id	sid	tid	token	lemma	pos
fnp-5848	1	1	neurodegeneration	neurodegeneration	NOUN
fnp-5848	1	2	:	:	PUNCT
fnp-5848	1	3	2024	2024	NUM
fnp-5848	1	4	update	update	NOUN
fnp-5848	1	5	free	free	ADJ
fnp-5848	1	6	neuropathology	neuropathology	NOUN
fnp-5848	1	7	5:31	5:31	NUM
fnp-5848	1	8	(	(	PUNCT
fnp-5848	1	9	2024	2024	NUM
fnp-5848	1	10	)	)	PUNCT
fnp-5848	1	11	john	john	PROPN
fnp-5848	1	12	f.	f.	PROPN
fnp-5848	1	13	crary	crary	PROPN
fnp-5848	1	14	doi	doi	PROPN
fnp-5848	1	15	:	:	PUNCT
fnp-5848	1	16	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	1	17	page	page	NOUN
fnp-5848	1	18	1	1	NUM
fnp-5848	1	19	of	of	ADP
fnp-5848	1	20	12	12	NUM
fnp-5848	1	21	copyright	copyright	NOUN
fnp-5848	1	22	:	:	PUNCT
fnp-5848	1	23	©	©	PROPN
fnp-5848	1	24	2024	2024	NUM
fnp-5848	1	25	the	the	DET
fnp-5848	1	26	author(s	author(s	NOUN
fnp-5848	1	27	)	)	PUNCT
fnp-5848	1	28	.	.	PUNCT
fnp-5848	2	1	this	this	PRON
fnp-5848	2	2	is	be	AUX
fnp-5848	2	3	an	an	DET
fnp-5848	2	4	open	open	ADJ
fnp-5848	2	5	access	access	NOUN
fnp-5848	2	6	article	article	NOUN
fnp-5848	2	7	distributed	distribute	VERB
fnp-5848	2	8	under	under	ADP
fnp-5848	2	9	the	the	DET
fnp-5848	2	10	terms	term	NOUN
fnp-5848	2	11	of	of	ADP
fnp-5848	2	12	the	the	DET
fnp-5848	2	13	creative	creative	ADJ
fnp-5848	2	14	commons	common	NOUN
fnp-5848	2	15	attribution	attribution	NOUN
fnp-5848	2	16	4.0	4.0	NUM
fnp-5848	2	17	international	international	ADJ
fnp-5848	2	18	license	license	NOUN
fnp-5848	2	19	(	(	PUNCT
fnp-5848	2	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	2	21	)	)	PUNCT
fnp-5848	2	22	,	,	PUNCT
fnp-5848	2	23	which	which	PRON
fnp-5848	2	24	permits	permit	VERB
fnp-5848	2	25	unrestricted	unrestricted	ADJ
fnp-5848	2	26	use	use	NOUN
fnp-5848	2	27	,	,	PUNCT
fnp-5848	2	28	distribution	distribution	NOUN
fnp-5848	2	29	,	,	PUNCT
fnp-5848	2	30	and	and	CCONJ
fnp-5848	2	31	reproduction	reproduction	NOUN
fnp-5848	2	32	in	in	ADP
fnp-5848	2	33	any	any	DET
fnp-5848	2	34	medium	medium	NOUN
fnp-5848	2	35	,	,	PUNCT
fnp-5848	2	36	provided	provide	VERB
fnp-5848	2	37	the	the	DET
fnp-5848	2	38	original	original	ADJ
fnp-5848	2	39	author	author	NOUN
fnp-5848	2	40	and	and	CCONJ
fnp-5848	2	41	source	source	NOUN
fnp-5848	2	42	are	be	AUX
fnp-5848	2	43	credited	credit	VERB
fnp-5848	2	44	,	,	PUNCT
fnp-5848	2	45	a	a	DET
fnp-5848	2	46	link	link	NOUN
fnp-5848	2	47	to	to	ADP
fnp-5848	2	48	the	the	DET
fnp-5848	2	49	creative	creative	ADJ
fnp-5848	2	50	commons	common	NOUN
fnp-5848	2	51	license	license	NOUN
fnp-5848	2	52	is	be	AUX
fnp-5848	2	53	provided	provide	VERB
fnp-5848	2	54	,	,	PUNCT
fnp-5848	2	55	and	and	CCONJ
fnp-5848	2	56	any	any	DET
fnp-5848	2	57	changes	change	NOUN
fnp-5848	2	58	are	be	AUX
fnp-5848	2	59	indicated	indicate	VERB
fnp-5848	2	60	.	.	PUNCT
fnp-5848	3	1	the	the	DET
fnp-5848	3	2	creative	creative	ADJ
fnp-5848	3	3	commons	common	NOUN
fnp-5848	3	4	public	public	ADJ
fnp-5848	3	5	domain	domain	NOUN
fnp-5848	3	6	dedication	dedication	NOUN
fnp-5848	3	7	waiver	waiver	NOUN
fnp-5848	3	8	(	(	PUNCT
fnp-5848	3	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5848	3	10	)	)	PUNCT
fnp-5848	3	11	applies	apply	VERB
fnp-5848	3	12	to	to	ADP
fnp-5848	3	13	the	the	DET
fnp-5848	3	14	data	datum	NOUN
fnp-5848	3	15	made	make	VERB
fnp-5848	3	16	available	available	ADJ
fnp-5848	3	17	in	in	ADP
fnp-5848	3	18	this	this	DET
fnp-5848	3	19	article	article	NOUN
fnp-5848	3	20	,	,	PUNCT
fnp-5848	3	21	unless	unless	SCONJ
fnp-5848	3	22	otherwise	otherwise	ADV
fnp-5848	3	23	stated	state	VERB
fnp-5848	3	24	.	.	PUNCT
fnp-5848	4	1	neurodegeneration	neurodegeneration	NOUN
fnp-5848	4	2	:	:	PUNCT
fnp-5848	4	3	2024	2024	NUM
fnp-5848	4	4	update	update	NOUN
fnp-5848	4	5	john	john	PROPN
fnp-5848	4	6	f.	f.	PROPN
fnp-5848	4	7	crary	crary	PROPN
fnp-5848	4	8	department	department	PROPN
fnp-5848	4	9	of	of	ADP
fnp-5848	4	10	pathology	pathology	PROPN
fnp-5848	4	11	,	,	PUNCT
fnp-5848	4	12	nash	nash	PROPN
fnp-5848	4	13	family	family	PROPN
fnp-5848	4	14	department	department	PROPN
fnp-5848	4	15	of	of	ADP
fnp-5848	4	16	neuroscience	neuroscience	NOUN
fnp-5848	4	17	,	,	PUNCT
fnp-5848	4	18	department	department	NOUN
fnp-5848	4	19	of	of	ADP
fnp-5848	4	20	artificial	artificial	ADJ
fnp-5848	4	21	intelligence	intelligence	PROPN
fnp-5848	4	22	&	&	CCONJ
fnp-5848	4	23	human	human	PROPN
fnp-5848	4	24	health	health	PROPN
fnp-5848	4	25	,	,	PUNCT
fnp-5848	4	26	neuropathology	neuropathology	NOUN
fnp-5848	4	27	brain	brain	PROPN
fnp-5848	4	28	bank	bank	PROPN
fnp-5848	4	29	&	&	CCONJ
fnp-5848	4	30	research	research	PROPN
fnp-5848	4	31	core	core	NOUN
fnp-5848	4	32	,	,	PUNCT
fnp-5848	4	33	ronald	ronald	PROPN
fnp-5848	4	34	m.	m.	PROPN
fnp-5848	4	35	loeb	loeb	PROPN
fnp-5848	4	36	center	center	PROPN
fnp-5848	4	37	for	for	ADP
fnp-5848	4	38	alzheimer	alzheimer	PROPN
fnp-5848	4	39	's	's	PART
fnp-5848	4	40	disease	disease	NOUN
fnp-5848	4	41	,	,	PUNCT
fnp-5848	4	42	friedman	friedman	PROPN
fnp-5848	4	43	brain	brain	PROPN
fnp-5848	4	44	institute	institute	PROPN
fnp-5848	4	45	,	,	PUNCT
fnp-5848	4	46	icahn	icahn	PROPN
fnp-5848	4	47	school	school	PROPN
fnp-5848	4	48	of	of	ADP
fnp-5848	4	49	medicine	medicine	NOUN
fnp-5848	4	50	at	at	ADP
fnp-5848	4	51	mount	mount	PROPN
fnp-5848	4	52	sinai	sinai	PROPN
fnp-5848	4	53	,	,	PUNCT
fnp-5848	4	54	new	new	PROPN
fnp-5848	4	55	york	york	PROPN
fnp-5848	4	56	,	,	PUNCT
fnp-5848	4	57	ny	ny	PROPN
fnp-5848	4	58	,	,	PUNCT
fnp-5848	4	59	usa	usa	PROPN
fnp-5848	4	60	corresponding	corresponding	PROPN
fnp-5848	4	61	author	author	NOUN
fnp-5848	4	62	:	:	PUNCT
fnp-5848	5	1	john	john	PROPN
fnp-5848	5	2	f.	f.	PROPN
fnp-5848	5	3	crary	crary	PROPN
fnp-5848	5	4	·	·	PUNCT
fnp-5848	5	5	icahn	icahn	PROPN
fnp-5848	5	6	school	school	NOUN
fnp-5848	5	7	of	of	ADP
fnp-5848	5	8	medicine	medicine	NOUN
fnp-5848	5	9	at	at	ADP
fnp-5848	5	10	mount	mount	PROPN
fnp-5848	5	11	sinai	sinai	PROPN
fnp-5848	5	12	·	·	PUNCT
fnp-5848	5	13	1	1	NUM
fnp-5848	5	14	gustave	gustave	X
fnp-5848	5	15	l.	l.	PROPN
fnp-5848	5	16	levy	levy	PROPN
fnp-5848	5	17	place	place	PROPN
fnp-5848	5	18	box	box	PROPN
fnp-5848	5	19	1194	1194	NUM
fnp-5848	5	20	·	·	PUNCT
fnp-5848	5	21	new	new	PROPN
fnp-5848	5	22	york	york	PROPN
fnp-5848	5	23	,	,	PUNCT
fnp-5848	5	24	ny	ny	PROPN
fnp-5848	5	25	10029	10029	NUM
fnp-5848	5	26	·	·	PUNCT
fnp-5848	5	27	usa	usa	PROPN
fnp-5848	5	28	john.crary@mountsinai.org	john.crary@mountsinai.org	PROPN
fnp-5848	5	29	submitted	submit	VERB
fnp-5848	5	30	:	:	PUNCT
fnp-5848	5	31	09	09	NUM
fnp-5848	5	32	september	september	PROPN
fnp-5848	5	33	2024	2024	NUM
fnp-5848	5	34	·	·	PUNCT
fnp-5848	5	35	accepted	accept	VERB
fnp-5848	5	36	:	:	PUNCT
fnp-5848	5	37	18	18	NUM
fnp-5848	5	38	november	november	PROPN
fnp-5848	5	39	2024	2024	NUM
fnp-5848	5	40	·	·	PUNCT
fnp-5848	5	41	copyedited	copyedit	VERB
fnp-5848	5	42	by	by	ADP
fnp-5848	5	43	:	:	PUNCT
fnp-5848	5	44	jerry	jerry	PROPN
fnp-5848	5	45	lou	lou	PROPN
fnp-5848	5	46	·	·	PUNCT
fnp-5848	5	47	published	publish	VERB
fnp-5848	5	48	:	:	PUNCT
fnp-5848	5	49	09	09	NUM
fnp-5848	5	50	december	december	PROPN
fnp-5848	5	51	2024	2024	NUM
fnp-5848	5	52	abstract	abstract	NOUN
fnp-5848	5	53	this	this	DET
fnp-5848	5	54	review	review	NOUN
fnp-5848	5	55	highlights	highlight	VERB
fnp-5848	5	56	a	a	DET
fnp-5848	5	57	collection	collection	NOUN
fnp-5848	5	58	of	of	ADP
fnp-5848	5	59	both	both	CCONJ
fnp-5848	5	60	diverse	diverse	ADJ
fnp-5848	5	61	and	and	CCONJ
fnp-5848	5	62	highly	highly	ADV
fnp-5848	5	63	impactful	impactful	ADJ
fnp-5848	5	64	studies	study	NOUN
fnp-5848	5	65	published	publish	VERB
fnp-5848	5	66	in	in	ADP
fnp-5848	5	67	the	the	DET
fnp-5848	5	68	previous	previous	ADJ
fnp-5848	5	69	year	year	NOUN
fnp-5848	5	70	selected	select	VERB
fnp-5848	5	71	by	by	ADP
fnp-5848	5	72	the	the	DET
fnp-5848	5	73	author	author	NOUN
fnp-5848	5	74	from	from	ADP
fnp-5848	5	75	the	the	DET
fnp-5848	5	76	neurodegenerative	neurodegenerative	ADJ
fnp-5848	5	77	neuropathology	neuropathology	NOUN
fnp-5848	5	78	literature	literature	NOUN
fnp-5848	5	79	.	.	PUNCT
fnp-5848	6	1	as	as	ADP
fnp-5848	6	2	with	with	ADP
fnp-5848	6	3	previous	previous	ADJ
fnp-5848	6	4	reviews	review	NOUN
fnp-5848	6	5	in	in	ADP
fnp-5848	6	6	this	this	DET
fnp-5848	6	7	series	series	NOUN
fnp-5848	6	8	,	,	PUNCT
fnp-5848	6	9	the	the	DET
fnp-5848	6	10	focus	focus	NOUN
fnp-5848	6	11	is	be	AUX
fnp-5848	6	12	,	,	PUNCT
fnp-5848	6	13	to	to	ADP
fnp-5848	6	14	the	the	DET
fnp-5848	6	15	best	good	ADJ
fnp-5848	6	16	of	of	ADP
fnp-5848	6	17	my	my	PRON
fnp-5848	6	18	ability	ability	NOUN
fnp-5848	6	19	,	,	PUNCT
fnp-5848	6	20	to	to	PART
fnp-5848	6	21	highlight	highlight	VERB
fnp-5848	6	22	human	human	ADJ
fnp-5848	6	23	tissue	tissue	NOUN
fnp-5848	6	24	-	-	PUNCT
fnp-5848	6	25	based	base	VERB
fnp-5848	6	26	experimentation	experimentation	NOUN
fnp-5848	6	27	most	most	ADV
fnp-5848	6	28	relevant	relevant	ADJ
fnp-5848	6	29	to	to	ADP
fnp-5848	6	30	experimental	experimental	ADJ
fnp-5848	6	31	and	and	CCONJ
fnp-5848	6	32	clinical	clinical	ADJ
fnp-5848	6	33	neuropathologists	neuropathologist	NOUN
fnp-5848	6	34	.	.	PUNCT
fnp-5848	7	1	a	a	DET
fnp-5848	7	2	concerted	concerted	ADJ
fnp-5848	7	3	effort	effort	NOUN
fnp-5848	7	4	was	be	AUX
fnp-5848	7	5	made	make	VERB
fnp-5848	7	6	to	to	PART
fnp-5848	7	7	balance	balance	VERB
fnp-5848	7	8	the	the	DET
fnp-5848	7	9	selected	select	VERB
fnp-5848	7	10	studies	study	NOUN
fnp-5848	7	11	across	across	ADP
fnp-5848	7	12	neurodegenerative	neurodegenerative	ADJ
fnp-5848	7	13	disease	disease	NOUN
fnp-5848	7	14	categories	category	NOUN
fnp-5848	7	15	,	,	PUNCT
fnp-5848	7	16	approaches	approach	NOUN
fnp-5848	7	17	,	,	PUNCT
fnp-5848	7	18	and	and	CCONJ
fnp-5848	7	19	methodologies	methodology	NOUN
fnp-5848	7	20	to	to	PART
fnp-5848	7	21	capture	capture	VERB
fnp-5848	7	22	the	the	DET
fnp-5848	7	23	breadth	breadth	NOUN
fnp-5848	7	24	of	of	ADP
fnp-5848	7	25	the	the	DET
fnp-5848	7	26	research	research	NOUN
fnp-5848	7	27	landscape	landscape	NOUN
fnp-5848	7	28	.	.	PUNCT
fnp-5848	8	1	these	these	DET
fnp-5848	8	2	studies	study	NOUN
fnp-5848	8	3	employ	employ	VERB
fnp-5848	8	4	a	a	DET
fnp-5848	8	5	range	range	NOUN
fnp-5848	8	6	of	of	ADP
fnp-5848	8	7	classical	classical	ADJ
fnp-5848	8	8	and	and	CCONJ
fnp-5848	8	9	state	state	NOUN
fnp-5848	8	10	-	-	PUNCT
fnp-5848	8	11	of	of	ADP
fnp-5848	8	12	-	-	PUNCT
fnp-5848	8	13	the	the	DET
fnp-5848	8	14	-	-	PUNCT
fnp-5848	8	15	art	art	NOUN
fnp-5848	8	16	methodologies	methodology	NOUN
fnp-5848	8	17	ranging	range	VERB
fnp-5848	8	18	from	from	ADP
fnp-5848	8	19	clinical	clinical	ADJ
fnp-5848	8	20	pathoanatomical	pathoanatomical	ADJ
fnp-5848	8	21	correlative	correlative	ADJ
fnp-5848	8	22	studies	study	NOUN
fnp-5848	8	23	to	to	ADP
fnp-5848	8	24	single	single	ADJ
fnp-5848	8	25	-	-	PUNCT
fnp-5848	8	26	cell	cell	NOUN
fnp-5848	8	27	rna	rna	NOUN
fnp-5848	8	28	sequencing	sequencing	NOUN
fnp-5848	8	29	,	,	PUNCT
fnp-5848	8	30	artificial	artificial	ADJ
fnp-5848	8	31	intelligence	intelligence	NOUN
fnp-5848	8	32	,	,	PUNCT
fnp-5848	8	33	and	and	CCONJ
fnp-5848	8	34	patient	patient	NOUN
fnp-5848	8	35	-	-	PUNCT
fnp-5848	8	36	derived	derive	VERB
fnp-5848	8	37	human	human	ADJ
fnp-5848	8	38	induced	induce	VERB
fnp-5848	8	39	pluripotent	pluripotent	ADJ
fnp-5848	8	40	stem	stem	NOUN
fnp-5848	8	41	cell	cell	NOUN
fnp-5848	8	42	models	model	NOUN
fnp-5848	8	43	.	.	PUNCT
fnp-5848	9	1	key	key	ADJ
fnp-5848	9	2	studies	study	NOUN
fnp-5848	9	3	include	include	VERB
fnp-5848	9	4	demonstration	demonstration	NOUN
fnp-5848	9	5	of	of	ADP
fnp-5848	9	6	the	the	DET
fnp-5848	9	7	earliest	early	ADJ
fnp-5848	9	8	pathological	pathological	ADJ
fnp-5848	9	9	changes	change	NOUN
fnp-5848	9	10	in	in	ADP
fnp-5848	9	11	young	young	ADJ
fnp-5848	9	12	patients	patient	NOUN
fnp-5848	9	13	with	with	ADP
fnp-5848	9	14	repetitive	repetitive	ADJ
fnp-5848	9	15	head	head	NOUN
fnp-5848	9	16	impacts	impact	NOUN
fnp-5848	9	17	(	(	PUNCT
fnp-5848	9	18	rhi	rhi	NOUN
fnp-5848	9	19	)	)	PUNCT
fnp-5848	9	20	,	,	PUNCT
fnp-5848	9	21	elucidation	elucidation	NOUN
fnp-5848	9	22	of	of	ADP
fnp-5848	9	23	the	the	DET
fnp-5848	9	24	longitudinal	longitudinal	ADJ
fnp-5848	9	25	trajectory	trajectory	NOUN
fnp-5848	9	26	of	of	ADP
fnp-5848	9	27	extra	extra	ADJ
fnp-5848	9	28	pyramidal	pyramidal	ADJ
fnp-5848	9	29	symptoms	symptom	NOUN
fnp-5848	9	30	in	in	ADP
fnp-5848	9	31	lewy	lewy	ADJ
fnp-5848	9	32	body	body	NOUN
fnp-5848	9	33	disease	disease	NOUN
fnp-5848	9	34	subtypes	subtype	NOUN
fnp-5848	9	35	,	,	PUNCT
fnp-5848	9	36	mapping	mapping	NOUN
fnp-5848	9	37	of	of	ADP
fnp-5848	9	38	cell	cell	NOUN
fnp-5848	9	39	-	-	PUNCT
fnp-5848	9	40	type	type	NOUN
fnp-5848	9	41	specific	specific	ADJ
fnp-5848	9	42	polygenic	polygenic	ADJ
fnp-5848	9	43	risk	risk	NOUN
fnp-5848	9	44	in	in	ADP
fnp-5848	9	45	alzheimer	alzheimer	PROPN
fnp-5848	9	46	’s	’s	PART
fnp-5848	9	47	disease	disease	NOUN
fnp-5848	9	48	to	to	ADP
fnp-5848	9	49	neuropathology	neuropathology	NOUN
fnp-5848	9	50	,	,	PUNCT
fnp-5848	9	51	a	a	DET
fnp-5848	9	52	novel	novel	ADJ
fnp-5848	9	53	measure	measure	NOUN
fnp-5848	9	54	of	of	ADP
fnp-5848	9	55	histological	histological	ADJ
fnp-5848	9	56	brain	brain	NOUN
fnp-5848	9	57	age	age	NOUN
fnp-5848	9	58	acceleration	acceleration	NOUN
fnp-5848	9	59	using	use	VERB
fnp-5848	9	60	artificial	artificial	ADJ
fnp-5848	9	61	intelligence	intelligence	NOUN
fnp-5848	9	62	,	,	PUNCT
fnp-5848	9	63	trends	trend	NOUN
fnp-5848	9	64	in	in	ADP
fnp-5848	9	65	cerebrovascular	cerebrovascular	ADJ
fnp-5848	9	66	pathologies	pathology	NOUN
fnp-5848	9	67	over	over	ADP
fnp-5848	9	68	25	25	NUM
fnp-5848	9	69	years	year	NOUN
fnp-5848	9	70	,	,	PUNCT
fnp-5848	9	71	associations	association	NOUN
fnp-5848	9	72	between	between	ADP
fnp-5848	9	73	rhi	rhi	PROPN
fnp-5848	9	74	and	and	CCONJ
fnp-5848	9	75	tdp-43	tdp-43	PROPN
fnp-5848	9	76	 	 	SPACE
fnp-5848	9	77	/	/	SYM
fnp-5848	9	78	 	 	SPACE
fnp-5848	9	79	hippocampal	hippocampal	ADJ
fnp-5848	9	80	sclerosis	sclerosis	NOUN
fnp-5848	9	81	,	,	PUNCT
fnp-5848	9	82	microglia	microglia	NOUN
fnp-5848	9	83	 	 	SPACE
fnp-5848	9	84	/	/	SYM
fnp-5848	9	85	 	 	SPACE
fnp-5848	9	86	t	t	NOUN
fnp-5848	9	87	-	-	PUNCT
fnp-5848	9	88	cell	cell	NOUN
fnp-5848	9	89	interaction	interaction	NOUN
fnp-5848	9	90	in	in	ADP
fnp-5848	9	91	neurodegeneration	neurodegeneration	NOUN
fnp-5848	9	92	,	,	PUNCT
fnp-5848	9	93	the	the	DET
fnp-5848	9	94	impact	impact	NOUN
fnp-5848	9	95	of	of	ADP
fnp-5848	9	96	viral	viral	ADJ
fnp-5848	9	97	exposures	exposure	NOUN
fnp-5848	9	98	on	on	ADP
fnp-5848	9	99	neurodegenerative	neurodegenerative	ADJ
fnp-5848	9	100	disease	disease	NOUN
fnp-5848	9	101	risk	risk	NOUN
fnp-5848	9	102	,	,	PUNCT
fnp-5848	9	103	and	and	CCONJ
fnp-5848	9	104	polyglutamine	polyglutamine	NOUN
fnp-5848	9	105	repeat	repeat	VERB
fnp-5848	9	106	expansion	expansion	NOUN
fnp-5848	9	107	disorders	disorder	NOUN
fnp-5848	9	108	.	.	PUNCT
fnp-5848	10	1	this	this	DET
fnp-5848	10	2	sampling	sampling	NOUN
fnp-5848	10	3	of	of	ADP
fnp-5848	10	4	the	the	DET
fnp-5848	10	5	literature	literature	NOUN
fnp-5848	10	6	collectively	collectively	ADV
fnp-5848	10	7	displays	display	VERB
fnp-5848	10	8	the	the	DET
fnp-5848	10	9	breadth	breadth	NOUN
fnp-5848	10	10	of	of	ADP
fnp-5848	10	11	the	the	DET
fnp-5848	10	12	progress	progress	NOUN
fnp-5848	10	13	being	be	AUX
fnp-5848	10	14	made	make	VERB
fnp-5848	10	15	in	in	ADP
fnp-5848	10	16	the	the	DET
fnp-5848	10	17	neuropathology	neuropathology	NOUN
fnp-5848	10	18	of	of	ADP
fnp-5848	10	19	neurodegenerative	neurodegenerative	ADJ
fnp-5848	10	20	diseases	disease	NOUN
fnp-5848	10	21	.	.	PUNCT
fnp-5848	11	1	keywords	keyword	NOUN
fnp-5848	11	2	:	:	PUNCT
fnp-5848	11	3	neurodegeneration	neurodegeneration	NOUN
fnp-5848	11	4	,	,	PUNCT
fnp-5848	11	5	neuropathology	neuropathology	NOUN
fnp-5848	11	6	,	,	PUNCT
fnp-5848	11	7	aging	aging	NOUN
fnp-5848	11	8	,	,	PUNCT
fnp-5848	11	9	alzheimer	alzheimer	PROPN
fnp-5848	11	10	’s	’s	PART
fnp-5848	11	11	disease	disease	NOUN
fnp-5848	11	12	,	,	PUNCT
fnp-5848	11	13	tauopathy	tauopathy	NOUN
fnp-5848	11	14	,	,	PUNCT
fnp-5848	11	15	α	α	NOUN
fnp-5848	11	16	-	-	PUNCT
fnp-5848	11	17	synucleinopathy	synucleinopathy	ADJ
fnp-5848	11	18	,	,	PUNCT
fnp-5848	11	19	tdp-43	tdp-43	NOUN
fnp-5848	11	20	proteinopathy	proteinopathy	ADJ
fnp-5848	11	21	,	,	PUNCT
fnp-5848	11	22	traumatic	traumatic	ADJ
fnp-5848	11	23	brain	brain	NOUN
fnp-5848	11	24	injury	injury	PROPN
fnp-5848	11	25	review	review	NOUN
fnp-5848	11	26	https://doi.org/10.17879/freeneuropathology-2024https://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	11	27	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5848	11	28	mailto:john.crary@mountsinai.org	mailto:john.crary@mountsinai.org	PROPN
fnp-5848	11	29	free	free	ADJ
fnp-5848	11	30	neuropathology	neuropathology	NOUN
fnp-5848	11	31	5:31	5:31	NUM
fnp-5848	11	32	(	(	PUNCT
fnp-5848	11	33	2024	2024	NUM
fnp-5848	11	34	)	)	PUNCT
fnp-5848	11	35	john	john	PROPN
fnp-5848	11	36	f.	f.	PROPN
fnp-5848	11	37	crary	crary	PROPN
fnp-5848	11	38	doi	doi	PROPN
fnp-5848	11	39	:	:	PUNCT
fnp-5848	11	40	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	11	41	page	page	NOUN
fnp-5848	11	42	2	2	NUM
fnp-5848	11	43	of	of	ADP
fnp-5848	11	44	12	12	NUM
fnp-5848	11	45	1	1	NUM
fnp-5848	11	46	.	.	PUNCT
fnp-5848	11	47	 	 	SPACE
fnp-5848	11	48	chronic	chronic	ADJ
fnp-5848	11	49	traumatic	traumatic	ADJ
fnp-5848	11	50	encephalopathy	encephalopathy	NOUN
fnp-5848	11	51	in	in	ADP
fnp-5848	11	52	young	young	ADJ
fnp-5848	11	53	athletes	athlete	NOUN
fnp-5848	11	54	’	'	PUNCT
fnp-5848	11	55	post	post	ADJ
fnp-5848	11	56	-	-	ADJ
fnp-5848	11	57	repetitive	repetitive	ADJ
fnp-5848	11	58	head	head	NOUN
fnp-5848	11	59	impacts	impact	NOUN
fnp-5848	11	60	concussions	concussion	NOUN
fnp-5848	11	61	are	be	AUX
fnp-5848	11	62	extremely	extremely	ADV
fnp-5848	11	63	prevalent	prevalent	ADJ
fnp-5848	11	64	,	,	PUNCT
fnp-5848	11	65	especially	especially	ADV
fnp-5848	11	66	among	among	ADP
fnp-5848	11	67	individuals	individual	NOUN
fnp-5848	11	68	exposed	expose	VERB
fnp-5848	11	69	to	to	ADP
fnp-5848	11	70	repetitive	repetitive	ADJ
fnp-5848	11	71	head	head	NOUN
fnp-5848	11	72	impacts	impact	NOUN
fnp-5848	11	73	(	(	PUNCT
fnp-5848	11	74	rhis	rhis	NOUN
fnp-5848	11	75	)	)	PUNCT
fnp-5848	11	76	through	through	ADP
fnp-5848	11	77	contact	contact	NOUN
fnp-5848	11	78	sports	sport	NOUN
fnp-5848	11	79	,	,	PUNCT
fnp-5848	11	80	military	military	ADJ
fnp-5848	11	81	service	service	NOUN
fnp-5848	11	82	,	,	PUNCT
fnp-5848	11	83	intimate	intimate	ADJ
fnp-5848	11	84	partner	partner	NOUN
fnp-5848	11	85	violence	violence	NOUN
fnp-5848	11	86	,	,	PUNCT
fnp-5848	11	87	and	and	CCONJ
fnp-5848	11	88	other	other	ADJ
fnp-5848	11	89	means	mean	NOUN
fnp-5848	11	90	.	.	PUNCT
fnp-5848	12	1	while	while	SCONJ
fnp-5848	12	2	these	these	DET
fnp-5848	12	3	impacts	impact	NOUN
fnp-5848	12	4	may	may	AUX
fnp-5848	12	5	be	be	AUX
fnp-5848	12	6	symptomatic	symptomatic	ADJ
fnp-5848	12	7	or	or	CCONJ
fnp-5848	12	8	asymptomatic	asymptomatic	ADJ
fnp-5848	12	9	in	in	ADP
fnp-5848	12	10	the	the	DET
fnp-5848	12	11	short	short	ADJ
fnp-5848	12	12	term	term	NOUN
fnp-5848	12	13	,	,	PUNCT
fnp-5848	12	14	long	long	ADJ
fnp-5848	12	15	-	-	PUNCT
fnp-5848	12	16	term	term	NOUN
fnp-5848	12	17	exposure	exposure	NOUN
fnp-5848	12	18	can	can	AUX
fnp-5848	12	19	lead	lead	VERB
fnp-5848	12	20	to	to	ADP
fnp-5848	12	21	severe	severe	ADJ
fnp-5848	12	22	neurological	neurological	ADJ
fnp-5848	12	23	outcomes	outcome	NOUN
fnp-5848	12	24	,	,	PUNCT
fnp-5848	12	25	including	include	VERB
fnp-5848	12	26	chronic	chronic	ADJ
fnp-5848	12	27	traumatic	traumatic	ADJ
fnp-5848	12	28	encephalopathy	encephalopathy	NOUN
fnp-5848	12	29	(	(	PUNCT
fnp-5848	12	30	cte	cte	NOUN
fnp-5848	12	31	)	)	PUNCT
fnp-5848	12	32	,	,	PUNCT
fnp-5848	12	33	a	a	DET
fnp-5848	12	34	degenerative	degenerative	ADJ
fnp-5848	12	35	brain	brain	NOUN
fnp-5848	12	36	disease	disease	NOUN
fnp-5848	12	37	with	with	ADP
fnp-5848	12	38	varied	varied	ADJ
fnp-5848	12	39	clinical	clinical	ADJ
fnp-5848	12	40	and	and	CCONJ
fnp-5848	12	41	neuropathological	neuropathological	ADJ
fnp-5848	12	42	features	feature	NOUN
fnp-5848	12	43	.	.	PUNCT
fnp-5848	13	1	most	most	ADJ
fnp-5848	13	2	research	research	NOUN
fnp-5848	13	3	on	on	ADP
fnp-5848	13	4	rhi	rhi	PROPN
fnp-5848	13	5	has	have	AUX
fnp-5848	13	6	focused	focus	VERB
fnp-5848	13	7	on	on	ADP
fnp-5848	13	8	older	old	ADJ
fnp-5848	13	9	populations	population	NOUN
fnp-5848	13	10	,	,	PUNCT
fnp-5848	13	11	leaving	leave	VERB
fnp-5848	13	12	a	a	DET
fnp-5848	13	13	critical	critical	ADJ
fnp-5848	13	14	gap	gap	NOUN
fnp-5848	13	15	in	in	ADP
fnp-5848	13	16	our	our	PRON
fnp-5848	13	17	understanding	understanding	NOUN
fnp-5848	13	18	of	of	ADP
fnp-5848	13	19	how	how	SCONJ
fnp-5848	13	20	rhis	rhis	PROPN
fnp-5848	13	21	affect	affect	VERB
fnp-5848	13	22	younger	young	ADJ
fnp-5848	13	23	individuals	individual	NOUN
fnp-5848	13	24	.	.	PUNCT
fnp-5848	14	1	investigating	investigate	VERB
fnp-5848	14	2	changes	change	NOUN
fnp-5848	14	3	in	in	ADP
fnp-5848	14	4	young	young	ADJ
fnp-5848	14	5	athletes	athlete	NOUN
fnp-5848	14	6	is	be	AUX
fnp-5848	14	7	crucial	crucial	ADJ
fnp-5848	14	8	,	,	PUNCT
fnp-5848	14	9	as	as	SCONJ
fnp-5848	14	10	it	it	PRON
fnp-5848	14	11	may	may	AUX
fnp-5848	14	12	uncover	uncover	VERB
fnp-5848	14	13	underlying	underlying	ADJ
fnp-5848	14	14	mechanisms	mechanism	NOUN
fnp-5848	14	15	for	for	ADP
fnp-5848	14	16	neuropsychiatric	neuropsychiatric	ADJ
fnp-5848	14	17	symptoms	symptom	NOUN
fnp-5848	14	18	and	and	CCONJ
fnp-5848	14	19	identify	identify	VERB
fnp-5848	14	20	early	early	ADJ
fnp-5848	14	21	triggers	trigger	NOUN
fnp-5848	14	22	for	for	ADP
fnp-5848	14	23	tau	tau	PROPN
fnp-5848	14	24	accumulation	accumulation	NOUN
fnp-5848	14	25	and	and	CCONJ
fnp-5848	14	26	associated	associated	ADJ
fnp-5848	14	27	toxicity	toxicity	NOUN
fnp-5848	14	28	,	,	PUNCT
fnp-5848	14	29	potentially	potentially	ADV
fnp-5848	14	30	informing	inform	VERB
fnp-5848	14	31	preventive	preventive	ADJ
fnp-5848	14	32	strategies	strategy	NOUN
fnp-5848	14	33	and	and	CCONJ
fnp-5848	14	34	interventions	intervention	NOUN
fnp-5848	14	35	.	.	PUNCT
fnp-5848	15	1	a	a	DET
fnp-5848	15	2	study	study	NOUN
fnp-5848	15	3	by	by	ADP
fnp-5848	15	4	mckee	mckee	PROPN
fnp-5848	15	5	et	et	PROPN
fnp-5848	15	6	al	al	PROPN
fnp-5848	15	7	.	.	PROPN
fnp-5848	15	8	published	publish	VERB
fnp-5848	15	9	in	in	ADP
fnp-5848	15	10	jama	jama	PROPN
fnp-5848	15	11	neurology	neurology	NOUN
fnp-5848	15	12	investigates	investigate	VERB
fnp-5848	15	13	the	the	DET
fnp-5848	15	14	neuropathologic	neuropathologic	ADJ
fnp-5848	15	15	and	and	CCONJ
fnp-5848	15	16	clinical	clinical	ADJ
fnp-5848	15	17	consequences	consequence	NOUN
fnp-5848	15	18	of	of	ADP
fnp-5848	15	19	repetitive	repetitive	ADJ
fnp-5848	15	20	head	head	NOUN
fnp-5848	15	21	impacts	impact	NOUN
fnp-5848	15	22	(	(	PUNCT
fnp-5848	15	23	rhis	rhis	NOUN
fnp-5848	15	24	)	)	PUNCT
fnp-5848	15	25	in	in	ADP
fnp-5848	15	26	young	young	ADJ
fnp-5848	15	27	contact	contact	NOUN
fnp-5848	15	28	sport	sport	NOUN
fnp-5848	15	29	athletes	athlete	NOUN
fnp-5848	15	30	(	(	PUNCT
fnp-5848	15	31	mckee	mckee	NOUN
fnp-5848	15	32	et	et	PROPN
fnp-5848	15	33	al	al	PROPN
fnp-5848	15	34	.	.	PROPN
fnp-5848	15	35	,	,	PUNCT
fnp-5848	15	36	2023	2023	NUM
fnp-5848	15	37	)	)	PUNCT
fnp-5848	15	38	.	.	PUNCT
fnp-5848	16	1	analyzing	analyze	VERB
fnp-5848	16	2	data	datum	NOUN
fnp-5848	16	3	from	from	ADP
fnp-5848	16	4	152	152	NUM
fnp-5848	16	5	brain	brain	NOUN
fnp-5848	16	6	donors	donor	NOUN
fnp-5848	16	7	younger	young	ADJ
fnp-5848	16	8	than	than	ADP
fnp-5848	16	9	30	30	NUM
fnp-5848	16	10	years	year	NOUN
fnp-5848	16	11	from	from	ADP
fnp-5848	16	12	the	the	DET
fnp-5848	16	13	unite	unite	NOUN
fnp-5848	16	14	brain	brain	NOUN
fnp-5848	16	15	bank	bank	NOUN
fnp-5848	16	16	,	,	PUNCT
fnp-5848	16	17	the	the	DET
fnp-5848	16	18	study	study	NOUN
fnp-5848	16	19	characterized	characterize	VERB
fnp-5848	16	20	the	the	DET
fnp-5848	16	21	presence	presence	NOUN
fnp-5848	16	22	and	and	CCONJ
fnp-5848	16	23	extent	extent	NOUN
fnp-5848	16	24	of	of	ADP
fnp-5848	16	25	chronic	chronic	ADJ
fnp-5848	16	26	traumatic	traumatic	ADJ
fnp-5848	16	27	encephalopathy	encephalopathy	NOUN
fnp-5848	16	28	(	(	PUNCT
fnp-5848	16	29	cte	cte	NOUN
fnp-5848	16	30	)	)	PUNCT
fnp-5848	16	31	and	and	CCONJ
fnp-5848	16	32	other	other	ADJ
fnp-5848	16	33	neuropathologic	neuropathologic	ADJ
fnp-5848	16	34	abnormalities	abnormality	NOUN
fnp-5848	16	35	.	.	PUNCT
fnp-5848	17	1	the	the	DET
fnp-5848	17	2	authors	author	NOUN
fnp-5848	17	3	found	find	VERB
fnp-5848	17	4	that	that	SCONJ
fnp-5848	17	5	41.4	41.4	NUM
fnp-5848	17	6	 	 	SPACE
fnp-5848	17	7	%	%	NOUN
fnp-5848	17	8	of	of	ADP
fnp-5848	17	9	the	the	DET
fnp-5848	17	10	athletes	athlete	NOUN
fnp-5848	17	11	showed	show	VERB
fnp-5848	17	12	neuropathological	neuropathological	ADJ
fnp-5848	17	13	changes	change	NOUN
fnp-5848	17	14	diagnostic	diagnostic	ADJ
fnp-5848	17	15	for	for	ADP
fnp-5848	17	16	cte	cte	NOUN
fnp-5848	17	17	,	,	PUNCT
fnp-5848	17	18	predominantly	predominantly	ADV
fnp-5848	17	19	mild	mild	ADJ
fnp-5848	17	20	(	(	PUNCT
fnp-5848	17	21	stages	stage	NOUN
fnp-5848	17	22	i	i	PRON
fnp-5848	17	23	or	or	CCONJ
fnp-5848	17	24	ii	ii	NUM
fnp-5848	17	25	)	)	PUNCT
fnp-5848	17	26	.	.	PUNCT
fnp-5848	18	1	notably	notably	ADV
fnp-5848	18	2	,	,	PUNCT
fnp-5848	18	3	athletes	athlete	NOUN
fnp-5848	18	4	with	with	ADP
fnp-5848	18	5	cte	cte	PROPN
fnp-5848	18	6	were	be	AUX
fnp-5848	18	7	more	more	ADV
fnp-5848	18	8	likely	likely	ADJ
fnp-5848	18	9	to	to	PART
fnp-5848	18	10	be	be	AUX
fnp-5848	18	11	older	old	ADJ
fnp-5848	18	12	and	and	CCONJ
fnp-5848	18	13	have	have	VERB
fnp-5848	18	14	longer	long	ADJ
fnp-5848	18	15	exposure	exposure	NOUN
fnp-5848	18	16	to	to	ADP
fnp-5848	18	17	rhi	rhi	PROPN
fnp-5848	18	18	,	,	PUNCT
fnp-5848	18	19	particularly	particularly	ADV
fnp-5848	18	20	american	american	ADJ
fnp-5848	18	21	football	football	NOUN
fnp-5848	18	22	.	.	PUNCT
fnp-5848	19	1	cte	cte	PROPN
fnp-5848	19	2	positive	positive	ADJ
fnp-5848	19	3	subjects	subject	NOUN
fnp-5848	19	4	showed	show	VERB
fnp-5848	19	5	key	key	ADJ
fnp-5848	19	6	neuropathologic	neuropathologic	ADJ
fnp-5848	19	7	features	feature	NOUN
fnp-5848	19	8	,	,	PUNCT
fnp-5848	19	9	including	include	VERB
fnp-5848	19	10	ventricular	ventricular	ADJ
fnp-5848	19	11	enlargement	enlargement	NOUN
fnp-5848	19	12	,	,	PUNCT
fnp-5848	19	13	cavum	cavum	PROPN
fnp-5848	19	14	septum	septum	PROPN
fnp-5848	19	15	pellucidum	pellucidum	PROPN
fnp-5848	19	16	,	,	PUNCT
fnp-5848	19	17	thalamic	thalamic	ADJ
fnp-5848	19	18	notching	notching	NOUN
fnp-5848	19	19	,	,	PUNCT
fnp-5848	19	20	and	and	CCONJ
fnp-5848	19	21	the	the	DET
fnp-5848	19	22	presence	presence	NOUN
fnp-5848	19	23	of	of	ADP
fnp-5848	19	24	perivascular	perivascular	PROPN
fnp-5848	19	25	pigmentladen	pigmentladen	ADJ
fnp-5848	19	26	macrophages	macrophage	NOUN
fnp-5848	19	27	in	in	ADP
fnp-5848	19	28	the	the	DET
fnp-5848	19	29	frontal	frontal	ADJ
fnp-5848	19	30	white	white	ADJ
fnp-5848	19	31	matter	matter	NOUN
fnp-5848	19	32	(	(	PUNCT
fnp-5848	19	33	figure	figure	NOUN
fnp-5848	19	34	 	 	SPACE
fnp-5848	19	35	1	1	NUM
fnp-5848	19	36	)	)	PUNCT
fnp-5848	19	37	.	.	PUNCT
fnp-5848	20	1	further	far	ADV
fnp-5848	20	2	,	,	PUNCT
fnp-5848	20	3	the	the	DET
fnp-5848	20	4	study	study	NOUN
fnp-5848	20	5	also	also	ADV
fnp-5848	20	6	examined	examine	VERB
fnp-5848	20	7	the	the	DET
fnp-5848	20	8	clinical	clinical	ADJ
fnp-5848	20	9	symptoms	symptom	NOUN
fnp-5848	20	10	reported	report	VERB
fnp-5848	20	11	by	by	ADP
fnp-5848	20	12	informants	informant	NOUN
fnp-5848	20	13	using	use	VERB
fnp-5848	20	14	standardized	standardized	ADJ
fnp-5848	20	15	scales	scale	NOUN
fnp-5848	20	16	,	,	PUNCT
fnp-5848	20	17	showing	show	VERB
fnp-5848	20	18	that	that	PRON
fnp-5848	20	19	cognitive	cognitive	ADJ
fnp-5848	20	20	,	,	PUNCT
fnp-5848	20	21	behavioral	behavioral	ADJ
fnp-5848	20	22	,	,	PUNCT
fnp-5848	20	23	and	and	CCONJ
fnp-5848	20	24	mood	mood	NOUN
fnp-5848	20	25	disturbances	disturbance	NOUN
fnp-5848	20	26	were	be	AUX
fnp-5848	20	27	prevalent	prevalent	ADJ
fnp-5848	20	28	among	among	ADP
fnp-5848	20	29	the	the	DET
fnp-5848	20	30	brain	brain	NOUN
fnp-5848	20	31	donors	donor	NOUN
fnp-5848	20	32	,	,	PUNCT
fnp-5848	20	33	regardless	regardless	ADV
fnp-5848	20	34	of	of	ADP
fnp-5848	20	35	cte	cte	PROPN
fnp-5848	20	36	status	status	NOUN
fnp-5848	20	37	.	.	PUNCT
fnp-5848	21	1	common	common	ADJ
fnp-5848	21	2	symptoms	symptom	NOUN
fnp-5848	21	3	included	include	VERB
fnp-5848	21	4	executive	executive	ADJ
fnp-5848	21	5	dysfunction	dysfunction	NOUN
fnp-5848	21	6	,	,	PUNCT
fnp-5848	21	7	impulse	impulse	ADJ
fnp-5848	21	8	control	control	NOUN
fnp-5848	21	9	issues	issue	NOUN
fnp-5848	21	10	,	,	PUNCT
fnp-5848	21	11	depression	depression	NOUN
fnp-5848	21	12	,	,	PUNCT
fnp-5848	21	13	and	and	CCONJ
fnp-5848	21	14	apathy	apathy	NOUN
fnp-5848	21	15	.	.	PUNCT
fnp-5848	22	1	this	this	DET
fnp-5848	22	2	study	study	NOUN
fnp-5848	22	3	provides	provide	VERB
fnp-5848	22	4	critical	critical	ADJ
fnp-5848	22	5	insights	insight	NOUN
fnp-5848	22	6	into	into	ADP
fnp-5848	22	7	the	the	DET
fnp-5848	22	8	early	early	ADJ
fnp-5848	22	9	manifestations	manifestation	NOUN
fnp-5848	22	10	of	of	ADP
fnp-5848	22	11	cte	cte	NOUN
fnp-5848	22	12	and	and	CCONJ
fnp-5848	22	13	other	other	ADJ
fnp-5848	22	14	brain	brain	NOUN
fnp-5848	22	15	pathologies	pathology	NOUN
fnp-5848	22	16	in	in	ADP
fnp-5848	22	17	young	young	ADJ
fnp-5848	22	18	athletes	athlete	NOUN
fnp-5848	22	19	,	,	PUNCT
fnp-5848	22	20	emphasizing	emphasize	VERB
fnp-5848	22	21	the	the	DET
fnp-5848	22	22	need	need	NOUN
fnp-5848	22	23	for	for	ADP
fnp-5848	22	24	prospective	prospective	ADJ
fnp-5848	22	25	studies	study	NOUN
fnp-5848	22	26	to	to	PART
fnp-5848	22	27	better	well	ADV
fnp-5848	22	28	understand	understand	VERB
fnp-5848	22	29	the	the	DET
fnp-5848	22	30	specific	specific	ADJ
fnp-5848	22	31	impacts	impact	NOUN
fnp-5848	22	32	of	of	ADP
fnp-5848	22	33	rhis	rhis	NOUN
fnp-5848	22	34	.	.	PUNCT
fnp-5848	23	1	the	the	DET
fnp-5848	23	2	study	study	NOUN
fnp-5848	23	3	's	's	PART
fnp-5848	23	4	findings	finding	NOUN
fnp-5848	23	5	are	be	AUX
fnp-5848	23	6	potentially	potentially	ADV
fnp-5848	23	7	pivotal	pivotal	ADJ
fnp-5848	23	8	for	for	ADP
fnp-5848	23	9	developing	develop	VERB
fnp-5848	23	10	strategies	strategy	NOUN
fnp-5848	23	11	to	to	PART
fnp-5848	23	12	mitigate	mitigate	VERB
fnp-5848	23	13	the	the	DET
fnp-5848	23	14	long	long	ADJ
fnp-5848	23	15	-	-	PUNCT
fnp-5848	23	16	term	term	NOUN
fnp-5848	23	17	effects	effect	NOUN
fnp-5848	23	18	of	of	ADP
fnp-5848	23	19	rhis	rhis	NOUN
fnp-5848	23	20	in	in	ADP
fnp-5848	23	21	contact	contact	NOUN
fnp-5848	23	22	sports	sport	NOUN
fnp-5848	23	23	.	.	PUNCT
fnp-5848	24	1	figure	figure	NOUN
fnp-5848	24	2	 	 	SPACE
fnp-5848	24	3	1	1	NUM
fnp-5848	24	4	.	.	PUNCT
fnp-5848	24	5	neuropathological	neuropathological	ADJ
fnp-5848	24	6	changes	change	NOUN
fnp-5848	24	7	in	in	ADP
fnp-5848	24	8	young	young	ADJ
fnp-5848	24	9	contact	contact	NOUN
fnp-5848	24	10	sports	sport	NOUN
fnp-5848	24	11	athletes	athlete	NOUN
fnp-5848	24	12	.	.	PUNCT
fnp-5848	25	1	a.	a.	NOUN
fnp-5848	25	2	immunohistochemistry	immunohistochemistry	PROPN
fnp-5848	25	3	for	for	ADP
fnp-5848	25	4	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-5848	25	5	tau	tau	PROPN
fnp-5848	25	6	showing	show	VERB
fnp-5848	25	7	the	the	DET
fnp-5848	25	8	pathognomonic	pathognomonic	ADJ
fnp-5848	25	9	perivascular	perivascular	ADJ
fnp-5848	25	10	lesion	lesion	NOUN
fnp-5848	25	11	.	.	PUNCT
fnp-5848	26	1	b.	b.	PROPN
fnp-5848	26	2	lh&e	lh&e	PROPN
fnp-5848	26	3	showing	show	VERB
fnp-5848	26	4	robust	robust	ADJ
fnp-5848	26	5	perivascular	perivascular	ADJ
fnp-5848	26	6	hemosiderin	hemosiderin	ADJ
fnp-5848	26	7	deposition	deposition	NOUN
fnp-5848	26	8	in	in	ADP
fnp-5848	26	9	the	the	DET
fnp-5848	26	10	white	white	ADJ
fnp-5848	26	11	matter	matter	NOUN
fnp-5848	26	12	.	.	PUNCT
fnp-5848	27	1	c.	c.	PROPN
fnp-5848	27	2	lh&e	lh&e	PROPN
fnp-5848	27	3	demonstrating	demonstrate	VERB
fnp-5848	27	4	white	white	ADJ
fnp-5848	27	5	matter	matter	NOUN
fnp-5848	27	6	rarefaction	rarefaction	NOUN
fnp-5848	27	7	.	.	PUNCT
fnp-5848	28	1	d.	d.	PROPN
fnp-5848	28	2	activated	activate	VERB
fnp-5848	28	3	microglial	microglial	ADJ
fnp-5848	28	4	clusters	cluster	NOUN
fnp-5848	28	5	are	be	AUX
fnp-5848	28	6	prominent	prominent	ADJ
fnp-5848	28	7	.	.	PUNCT
fnp-5848	29	1	reproduced	reproduce	VERB
fnp-5848	29	2	with	with	ADP
fnp-5848	29	3	modifications	modification	NOUN
fnp-5848	29	4	under	under	ADP
fnp-5848	29	5	the	the	DET
fnp-5848	29	6	terms	term	NOUN
fnp-5848	29	7	of	of	ADP
fnp-5848	29	8	the	the	DET
fnp-5848	29	9	cc	cc	NOUN
fnp-5848	29	10	-	-	PUNCT
fnp-5848	29	11	by	by	ADJ
fnp-5848	29	12	license	license	NOUN
fnp-5848	29	13	(	(	PUNCT
fnp-5848	29	14	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	29	15	)	)	PUNCT
fnp-5848	29	16	.	.	PUNCT
fnp-5848	30	1	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	30	2	free	free	ADJ
fnp-5848	30	3	neuropathology	neuropathology	NOUN
fnp-5848	30	4	5:31	5:31	NUM
fnp-5848	30	5	(	(	PUNCT
fnp-5848	30	6	2024	2024	NUM
fnp-5848	30	7	)	)	PUNCT
fnp-5848	30	8	john	john	PROPN
fnp-5848	30	9	f.	f.	PROPN
fnp-5848	30	10	crary	crary	PROPN
fnp-5848	30	11	doi	doi	PROPN
fnp-5848	30	12	:	:	PUNCT
fnp-5848	30	13	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	30	14	page	page	NOUN
fnp-5848	30	15	3	3	NUM
fnp-5848	30	16	of	of	ADP
fnp-5848	30	17	12	12	NUM
fnp-5848	30	18	2	2	NUM
fnp-5848	30	19	.	.	PUNCT
fnp-5848	30	20	 	 	SPACE
fnp-5848	30	21	hippocampal	hippocampal	ADJ
fnp-5848	30	22	sclerosis	sclerosis	NOUN
fnp-5848	30	23	with	with	ADP
fnp-5848	30	24	tdp-43	tdp-43	NOUN
fnp-5848	30	25	inclusions	inclusion	NOUN
fnp-5848	30	26	following	follow	VERB
fnp-5848	30	27	repetitive	repetitive	ADJ
fnp-5848	30	28	head	head	NOUN
fnp-5848	30	29	impacts	impact	NOUN
fnp-5848	30	30	hippocampal	hippocampal	ADJ
fnp-5848	30	31	sclerosis	sclerosis	NOUN
fnp-5848	30	32	of	of	ADP
fnp-5848	30	33	aging	aging	NOUN
fnp-5848	30	34	,	,	PUNCT
fnp-5848	30	35	characterized	characterize	VERB
fnp-5848	30	36	by	by	ADP
fnp-5848	30	37	neuronal	neuronal	ADJ
fnp-5848	30	38	loss	loss	NOUN
fnp-5848	30	39	and	and	CCONJ
fnp-5848	30	40	gliosis	gliosis	NOUN
fnp-5848	30	41	primarily	primarily	ADV
fnp-5848	30	42	in	in	ADP
fnp-5848	30	43	the	the	DET
fnp-5848	30	44	ca1	ca1	PROPN
fnp-5848	30	45	region	region	NOUN
fnp-5848	30	46	and	and	CCONJ
fnp-5848	30	47	occurring	occur	VERB
fnp-5848	30	48	independently	independently	ADV
fnp-5848	30	49	of	of	ADP
fnp-5848	30	50	hypoxic	hypoxic	ADJ
fnp-5848	30	51	ischemic	ischemic	ADJ
fnp-5848	30	52	injury	injury	NOUN
fnp-5848	30	53	,	,	PUNCT
fnp-5848	30	54	is	be	AUX
fnp-5848	30	55	prevalent	prevalent	ADJ
fnp-5848	30	56	in	in	ADP
fnp-5848	30	57	the	the	DET
fnp-5848	30	58	aging	age	VERB
fnp-5848	30	59	population	population	NOUN
fnp-5848	30	60	.	.	PUNCT
fnp-5848	31	1	most	most	ADJ
fnp-5848	31	2	cases	case	NOUN
fnp-5848	31	3	also	also	ADV
fnp-5848	31	4	exhibit	exhibit	VERB
fnp-5848	31	5	inclusions	inclusion	NOUN
fnp-5848	31	6	positive	positive	ADJ
fnp-5848	31	7	for	for	ADP
fnp-5848	31	8	transactive	transactive	ADJ
fnp-5848	31	9	response	response	NOUN
fnp-5848	31	10	dna	dna	NOUN
fnp-5848	31	11	-	-	PUNCT
fnp-5848	31	12	binding	bind	VERB
fnp-5848	31	13	protein	protein	NOUN
fnp-5848	31	14	with	with	ADP
fnp-5848	31	15	43	43	NUM
fnp-5848	31	16	kda	kda	NOUN
fnp-5848	31	17	(	(	PUNCT
fnp-5848	31	18	tdp-43	tdp-43	PROPN
fnp-5848	31	19	)	)	PUNCT
fnp-5848	31	20	,	,	PUNCT
fnp-5848	31	21	a	a	DET
fnp-5848	31	22	protein	protein	NOUN
fnp-5848	31	23	that	that	PRON
fnp-5848	31	24	,	,	PUNCT
fnp-5848	31	25	since	since	SCONJ
fnp-5848	31	26	its	its	PRON
fnp-5848	31	27	identification	identification	NOUN
fnp-5848	31	28	as	as	ADP
fnp-5848	31	29	the	the	DET
fnp-5848	31	30	primary	primary	ADJ
fnp-5848	31	31	inclusion	inclusion	NOUN
fnp-5848	31	32	in	in	ADP
fnp-5848	31	33	amyotrophic	amyotrophic	ADJ
fnp-5848	31	34	lateral	lateral	ADJ
fnp-5848	31	35	sclerosis	sclerosis	NOUN
fnp-5848	31	36	(	(	PUNCT
fnp-5848	31	37	als	als	NOUN
fnp-5848	31	38	)	)	PUNCT
fnp-5848	31	39	and	and	CCONJ
fnp-5848	31	40	frontotemporal	frontotemporal	ADJ
fnp-5848	31	41	lobar	lobar	ADJ
fnp-5848	31	42	degeneration	degeneration	NOUN
fnp-5848	31	43	(	(	PUNCT
fnp-5848	31	44	ftld	ftld	ADJ
fnp-5848	31	45	)	)	PUNCT
fnp-5848	31	46	,	,	PUNCT
fnp-5848	31	47	has	have	AUX
fnp-5848	31	48	been	be	AUX
fnp-5848	31	49	linked	link	VERB
fnp-5848	31	50	to	to	ADP
fnp-5848	31	51	other	other	ADJ
fnp-5848	31	52	disorders	disorder	NOUN
fnp-5848	31	53	including	include	VERB
fnp-5848	31	54	alzheimer	alzheimer	PROPN
fnp-5848	31	55	's	's	PART
fnp-5848	31	56	disease	disease	NOUN
fnp-5848	31	57	(	(	PUNCT
fnp-5848	31	58	ad	ad	NOUN
fnp-5848	31	59	)	)	PUNCT
fnp-5848	31	60	,	,	PUNCT
fnp-5848	31	61	limbic	limbic	ADJ
fnp-5848	31	62	age	age	NOUN
fnp-5848	31	63	-	-	PUNCT
fnp-5848	31	64	related	relate	VERB
fnp-5848	31	65	tdp-43	tdp-43	NOUN
fnp-5848	31	66	encephalopathy	encephalopathy	ADJ
fnp-5848	31	67	neuropathologic	neuropathologic	ADJ
fnp-5848	31	68	change	change	NOUN
fnp-5848	31	69	(	(	PUNCT
fnp-5848	31	70	late	late	PROPN
fnp-5848	31	71	-	-	PUNCT
fnp-5848	31	72	nc	nc	NOUN
fnp-5848	31	73	)	)	PUNCT
fnp-5848	31	74	,	,	PUNCT
fnp-5848	31	75	and	and	CCONJ
fnp-5848	31	76	chronic	chronic	ADJ
fnp-5848	31	77	traumatic	traumatic	ADJ
fnp-5848	31	78	encephalopathy	encephalopathy	NOUN
fnp-5848	31	79	(	(	PUNCT
fnp-5848	31	80	cte	cte	NOUN
fnp-5848	31	81	)	)	PUNCT
fnp-5848	31	82	.	.	PUNCT
fnp-5848	32	1	the	the	DET
fnp-5848	32	2	association	association	NOUN
fnp-5848	32	3	with	with	ADP
fnp-5848	32	4	cte	cte	PROPN
fnp-5848	32	5	is	be	AUX
fnp-5848	32	6	particularly	particularly	ADV
fnp-5848	32	7	notable	notable	ADJ
fnp-5848	32	8	and	and	CCONJ
fnp-5848	32	9	understudied	understudied	ADJ
fnp-5848	32	10	,	,	PUNCT
fnp-5848	32	11	raising	raise	VERB
fnp-5848	32	12	questions	question	NOUN
fnp-5848	32	13	about	about	ADP
fnp-5848	32	14	whether	whether	SCONJ
fnp-5848	32	15	these	these	DET
fnp-5848	32	16	conditions	condition	NOUN
fnp-5848	32	17	represent	represent	VERB
fnp-5848	32	18	co	co	NOUN
fnp-5848	32	19	-	-	NOUN
fnp-5848	32	20	morbidities	morbidity	NOUN
fnp-5848	32	21	or	or	CCONJ
fnp-5848	32	22	if	if	SCONJ
fnp-5848	32	23	they	they	PRON
fnp-5848	32	24	have	have	VERB
fnp-5848	32	25	synergistic	synergistic	ADJ
fnp-5848	32	26	effects	effect	NOUN
fnp-5848	32	27	.	.	PUNCT
fnp-5848	33	1	a	a	DET
fnp-5848	33	2	study	study	NOUN
fnp-5848	33	3	by	by	ADP
fnp-5848	33	4	nicks	nick	NOUN
fnp-5848	33	5	et	et	PROPN
fnp-5848	33	6	al	al	PROPN
fnp-5848	33	7	.	.	PROPN
fnp-5848	33	8	published	publish	VERB
fnp-5848	33	9	in	in	ADP
fnp-5848	33	10	acta	acta	PROPN
fnp-5848	33	11	neuropathologica	neuropathologica	PROPN
fnp-5848	33	12	directly	directly	ADV
fnp-5848	33	13	addresses	address	VERB
fnp-5848	33	14	the	the	DET
fnp-5848	33	15	neuropatholo	neuropatholo	PROPN
fnp-5848	33	16	gical	gical	ADJ
fnp-5848	33	17	association	association	NOUN
fnp-5848	33	18	between	between	ADP
fnp-5848	33	19	repetitive	repetitive	ADJ
fnp-5848	33	20	head	head	NOUN
fnp-5848	33	21	impacts	impact	NOUN
fnp-5848	33	22	(	(	PUNCT
fnp-5848	33	23	rhi	rhi	NOUN
fnp-5848	33	24	)	)	PUNCT
fnp-5848	33	25	,	,	PUNCT
fnp-5848	33	26	chronic	chronic	ADJ
fnp-5848	33	27	traumatic	traumatic	ADJ
fnp-5848	33	28	encephalopathy	encephalopathy	NOUN
fnp-5848	33	29	(	(	PUNCT
fnp-5848	33	30	cte	cte	NOUN
fnp-5848	33	31	)	)	PUNCT
fnp-5848	33	32	,	,	PUNCT
fnp-5848	33	33	and	and	CCONJ
fnp-5848	33	34	the	the	DET
fnp-5848	33	35	presence	presence	NOUN
fnp-5848	33	36	of	of	ADP
fnp-5848	33	37	tdp-43	tdp-43	NOUN
fnp-5848	33	38	inclusions	inclusion	NOUN
fnp-5848	33	39	and	and	CCONJ
fnp-5848	33	40	hippocampal	hippocampal	ADJ
fnp-5848	33	41	sclerosis	sclerosis	NOUN
fnp-5848	33	42	(	(	PUNCT
fnp-5848	33	43	hs	hs	X
fnp-5848	33	44	)	)	PUNCT
fnp-5848	33	45	(	(	PUNCT
fnp-5848	33	46	nicks	nick	NOUN
fnp-5848	33	47	et	et	PROPN
fnp-5848	33	48	al	al	PROPN
fnp-5848	33	49	.	.	PROPN
fnp-5848	33	50	,	,	PUNCT
fnp-5848	33	51	2023	2023	NUM
fnp-5848	33	52	)	)	PUNCT
fnp-5848	33	53	.	.	PUNCT
fnp-5848	34	1	the	the	DET
fnp-5848	34	2	researchers	researcher	NOUN
fnp-5848	34	3	analyzed	analyze	VERB
fnp-5848	34	4	brain	brain	NOUN
fnp-5848	34	5	samples	sample	NOUN
fnp-5848	34	6	from	from	ADP
fnp-5848	34	7	401	401	NUM
fnp-5848	34	8	participants	participant	NOUN
fnp-5848	34	9	with	with	ADP
fnp-5848	34	10	a	a	DET
fnp-5848	34	11	history	history	NOUN
fnp-5848	34	12	of	of	ADP
fnp-5848	34	13	rhi	rhi	PROPN
fnp-5848	34	14	and	and	CCONJ
fnp-5848	34	15	neuropathologically	neuropathologically	ADV
fnp-5848	34	16	diagnosed	diagnose	VERB
fnp-5848	34	17	cte	cte	NOUN
fnp-5848	34	18	and	and	CCONJ
fnp-5848	34	19	compared	compare	VERB
fnp-5848	34	20	them	they	PRON
fnp-5848	34	21	with	with	ADP
fnp-5848	34	22	33	33	NUM
fnp-5848	34	23	individuals	individual	NOUN
fnp-5848	34	24	diagnosed	diagnose	VERB
fnp-5848	34	25	with	with	ADP
fnp-5848	34	26	hs	hs	PROPN
fnp-5848	34	27	without	without	ADP
fnp-5848	34	28	cte	cte	PROPN
fnp-5848	34	29	.	.	PUNCT
fnp-5848	35	1	the	the	DET
fnp-5848	35	2	study	study	NOUN
fnp-5848	35	3	found	find	VERB
fnp-5848	35	4	that	that	SCONJ
fnp-5848	35	5	hs	hs	PROPN
fnp-5848	35	6	was	be	AUX
fnp-5848	35	7	present	present	ADJ
fnp-5848	35	8	in	in	ADP
fnp-5848	35	9	23.4	23.4	NUM
fnp-5848	35	10	 	 	SPACE
fnp-5848	35	11	%	%	NOUN
fnp-5848	35	12	of	of	ADP
fnp-5848	35	13	the	the	DET
fnp-5848	35	14	cte	cte	NOUN
fnp-5848	35	15	cases	case	NOUN
fnp-5848	35	16	and	and	CCONJ
fnp-5848	35	17	that	that	SCONJ
fnp-5848	35	18	tdp-43	tdp-43	VERB
fnp-5848	35	19	inclusions	inclusion	NOUN
fnp-5848	35	20	were	be	AUX
fnp-5848	35	21	present	present	ADJ
fnp-5848	35	22	in	in	ADP
fnp-5848	35	23	43.3	43.3	NUM
fnp-5848	35	24	 	 	SPACE
fnp-5848	35	25	%	%	NOUN
fnp-5848	35	26	of	of	ADP
fnp-5848	35	27	the	the	DET
fnp-5848	35	28	cte	cte	PROPN
fnp-5848	35	29	cases	case	NOUN
fnp-5848	35	30	.	.	PUNCT
fnp-5848	36	1	notably	notably	ADV
fnp-5848	36	2	,	,	PUNCT
fnp-5848	36	3	hs	hs	PROPN
fnp-5848	36	4	in	in	ADP
fnp-5848	36	5	cte	cte	PROPN
fnp-5848	36	6	occurred	occur	VERB
fnp-5848	36	7	at	at	ADP
fnp-5848	36	8	a	a	DET
fnp-5848	36	9	younger	young	ADJ
fnp-5848	36	10	mean	mean	NOUN
fnp-5848	36	11	age	age	NOUN
fnp-5848	36	12	(	(	PUNCT
fnp-5848	36	13	77	77	NUM
fnp-5848	36	14	years	year	NOUN
fnp-5848	36	15	)	)	PUNCT
fnp-5848	36	16	and	and	CCONJ
fnp-5848	36	17	was	be	AUX
fnp-5848	36	18	significantly	significantly	ADV
fnp-5848	36	19	associated	associate	VERB
fnp-5848	36	20	with	with	ADP
fnp-5848	36	21	a	a	DET
fnp-5848	36	22	longer	long	ADJ
fnp-5848	36	23	history	history	NOUN
fnp-5848	36	24	of	of	ADP
fnp-5848	36	25	contact	contact	NOUN
fnp-5848	36	26	sports	sport	NOUN
fnp-5848	36	27	exposure	exposure	NOUN
fnp-5848	36	28	compared	compare	VERB
fnp-5848	36	29	to	to	ADP
fnp-5848	36	30	cte	cte	VERB
fnp-5848	36	31	without	without	ADP
fnp-5848	36	32	hs	hs	PROPN
fnp-5848	36	33	.	.	PROPN
fnp-5848	36	34	tdp-43	tdp-43	NOUN
fnp-5848	36	35	inclusions	inclusion	NOUN
fnp-5848	36	36	were	be	AUX
fnp-5848	36	37	frequently	frequently	ADV
fnp-5848	36	38	observed	observe	VERB
fnp-5848	36	39	in	in	ADP
fnp-5848	36	40	the	the	DET
fnp-5848	36	41	frontal	frontal	ADJ
fnp-5848	36	42	cortex	cortex	NOUN
fnp-5848	36	43	and	and	CCONJ
fnp-5848	36	44	often	often	ADV
fnp-5848	36	45	co	co	VERB
fnp-5848	36	46	-	-	VERB
fnp-5848	36	47	occurred	occur	VERB
fnp-5848	36	48	with	with	ADP
fnp-5848	36	49	limbic	limbic	ADJ
fnp-5848	36	50	tdp-43	tdp-43	PROPN
fnp-5848	36	51	pathology	pathology	PROPN
fnp-5848	36	52	.	.	PUNCT
fnp-5848	37	1	structural	structural	ADJ
fnp-5848	37	2	equation	equation	NOUN
fnp-5848	37	3	modeling	modeling	NOUN
fnp-5848	37	4	demonstrated	demonstrate	VERB
fnp-5848	37	5	a	a	DET
fnp-5848	37	6	significant	significant	ADJ
fnp-5848	37	7	association	association	NOUN
fnp-5848	37	8	between	between	ADP
fnp-5848	37	9	years	year	NOUN
fnp-5848	37	10	of	of	ADP
fnp-5848	37	11	rhi	rhi	PROPN
fnp-5848	37	12	exposure	exposure	NOUN
fnp-5848	37	13	and	and	CCONJ
fnp-5848	37	14	the	the	DET
fnp-5848	37	15	presence	presence	NOUN
fnp-5848	37	16	of	of	ADP
fnp-5848	37	17	hippocampal	hippocampal	ADJ
fnp-5848	37	18	tdp-43	tdp-43	NOUN
fnp-5848	37	19	inclusions	inclusion	NOUN
fnp-5848	37	20	through	through	ADP
fnp-5848	37	21	increased	increase	VERB
fnp-5848	37	22	cte	cte	NOUN
fnp-5848	37	23	stage	stage	NOUN
fnp-5848	37	24	.	.	PUNCT
fnp-5848	38	1	the	the	DET
fnp-5848	38	2	study	study	NOUN
fnp-5848	38	3	also	also	ADV
fnp-5848	38	4	showed	show	VERB
fnp-5848	38	5	that	that	SCONJ
fnp-5848	38	6	tdp-43	tdp-43	VERB
fnp-5848	38	7	inclusions	inclusion	NOUN
fnp-5848	38	8	in	in	ADP
fnp-5848	38	9	cte	cte	NOUN
fnp-5848	38	10	were	be	AUX
fnp-5848	38	11	predominantly	predominantly	ADV
fnp-5848	38	12	limbic	limbic	ADJ
fnp-5848	38	13	but	but	CCONJ
fnp-5848	38	14	also	also	ADV
fnp-5848	38	15	involved	involve	VERB
fnp-5848	38	16	the	the	DET
fnp-5848	38	17	frontal	frontal	ADJ
fnp-5848	38	18	cortex	cortex	NOUN
fnp-5848	38	19	,	,	PUNCT
fnp-5848	38	20	distinguishing	distinguish	VERB
fnp-5848	38	21	it	it	PRON
fnp-5848	38	22	from	from	ADP
fnp-5848	38	23	typical	typical	ADJ
fnp-5848	38	24	age	age	NOUN
fnp-5848	38	25	-	-	PUNCT
fnp-5848	38	26	related	relate	VERB
fnp-5848	38	27	tdp-43	tdp-43	NOUN
fnp-5848	38	28	patho	patho	PROPN
fnp-5848	38	29	logies	logie	VERB
fnp-5848	38	30	such	such	ADJ
fnp-5848	38	31	as	as	ADP
fnp-5848	38	32	late	late	ADJ
fnp-5848	38	33	-	-	PUNCT
fnp-5848	38	34	nc	nc	PROPN
fnp-5848	38	35	.	.	PUNCT
fnp-5848	39	1	the	the	DET
fnp-5848	39	2	presence	presence	NOUN
fnp-5848	39	3	of	of	ADP
fnp-5848	39	4	tdp-43	tdp-43	NOUN
fnp-5848	39	5	inclusions	inclusion	NOUN
fnp-5848	39	6	in	in	ADP
fnp-5848	39	7	the	the	DET
fnp-5848	39	8	hippocampus	hippocampus	NOUN
fnp-5848	39	9	was	be	AUX
fnp-5848	39	10	significantly	significantly	ADV
fnp-5848	39	11	associated	associate	VERB
fnp-5848	39	12	with	with	ADP
fnp-5848	39	13	hs	hs	PROPN
fnp-5848	39	14	in	in	ADP
fnp-5848	39	15	cte	cte	PROPN
fnp-5848	39	16	,	,	PUNCT
fnp-5848	39	17	suggesting	suggest	VERB
fnp-5848	39	18	a	a	DET
fnp-5848	39	19	pathogenic	pathogenic	ADJ
fnp-5848	39	20	link	link	NOUN
fnp-5848	39	21	between	between	ADP
fnp-5848	39	22	repetitive	repetitive	ADJ
fnp-5848	39	23	head	head	NOUN
fnp-5848	39	24	impacts	impact	NOUN
fnp-5848	39	25	,	,	PUNCT
fnp-5848	39	26	cte	cte	PROPN
fnp-5848	39	27	patho	patho	PROPN
fnp-5848	39	28	logy	logy	NOUN
fnp-5848	39	29	,	,	PUNCT
fnp-5848	39	30	and	and	CCONJ
fnp-5848	39	31	the	the	DET
fnp-5848	39	32	development	development	NOUN
fnp-5848	39	33	of	of	ADP
fnp-5848	39	34	tdp-43	tdp-43	PROPN
fnp-5848	39	35	proteinopathy	proteinopathy	ADJ
fnp-5848	39	36	and	and	CCONJ
fnp-5848	39	37	hs	hs	PROPN
fnp-5848	39	38	.	.	PUNCT
fnp-5848	40	1	these	these	DET
fnp-5848	40	2	findings	finding	NOUN
fnp-5848	40	3	highlight	highlight	VERB
fnp-5848	40	4	the	the	DET
fnp-5848	40	5	importance	importance	NOUN
fnp-5848	40	6	of	of	ADP
fnp-5848	40	7	considering	consider	VERB
fnp-5848	40	8	rhi	rhi	PROPN
fnp-5848	40	9	history	history	NOUN
fnp-5848	40	10	in	in	ADP
fnp-5848	40	11	the	the	DET
fnp-5848	40	12	assessment	assessment	NOUN
fnp-5848	40	13	of	of	ADP
fnp-5848	40	14	hippocampal	hippocampal	ADJ
fnp-5848	40	15	sclerosis	sclerosis	NOUN
fnp-5848	40	16	and	and	CCONJ
fnp-5848	40	17	suggest	suggest	VERB
fnp-5848	40	18	potential	potential	ADJ
fnp-5848	40	19	therapeutic	therapeutic	ADJ
fnp-5848	40	20	targets	target	NOUN
fnp-5848	40	21	for	for	ADP
fnp-5848	40	22	mitigating	mitigate	VERB
fnp-5848	40	23	the	the	DET
fnp-5848	40	24	effects	effect	NOUN
fnp-5848	40	25	of	of	ADP
fnp-5848	40	26	rhi	rhi	PROPN
fnp-5848	40	27	on	on	ADP
fnp-5848	40	28	neurodegeneration	neurodegeneration	NOUN
fnp-5848	40	29	.	.	PUNCT
fnp-5848	41	1	3	3	X
fnp-5848	41	2	.	.	X
fnp-5848	41	3	 	 	SPACE
fnp-5848	41	4	longitudinal	longitudinal	ADJ
fnp-5848	41	5	motor	motor	NOUN
fnp-5848	41	6	decline	decline	NOUN
fnp-5848	41	7	in	in	ADP
fnp-5848	41	8	diffuse	diffuse	PROPN
fnp-5848	41	9	lewy	lewy	ADJ
fnp-5848	41	10	body	body	NOUN
fnp-5848	41	11	disease	disease	NOUN
fnp-5848	41	12	,	,	PUNCT
fnp-5848	41	13	parkinson	parkinson	NOUN
fnp-5848	41	14	’s	’s	PART
fnp-5848	41	15	disease	disease	NOUN
fnp-5848	41	16	with	with	ADP
fnp-5848	41	17	dementia	dementia	NOUN
fnp-5848	41	18	,	,	PUNCT
fnp-5848	41	19	and	and	CCONJ
fnp-5848	41	20	alzheimer	alzheimer	PROPN
fnp-5848	41	21	’s	’s	PART
fnp-5848	41	22	disease	disease	NOUN
fnp-5848	41	23	lewy	lewy	PROPN
fnp-5848	41	24	bodies	bodies	PROPN
fnp-5848	41	25	,	,	PUNCT
fnp-5848	41	26	a	a	DET
fnp-5848	41	27	common	common	ADJ
fnp-5848	41	28	neuropathological	neuropathological	ADJ
fnp-5848	41	29	finding	finding	NOUN
fnp-5848	41	30	,	,	PUNCT
fnp-5848	41	31	are	be	AUX
fnp-5848	41	32	the	the	DET
fnp-5848	41	33	hallmark	hallmark	NOUN
fnp-5848	41	34	of	of	ADP
fnp-5848	41	35	parkinson	parkinson	NOUN
fnp-5848	41	36	's	's	PART
fnp-5848	41	37	disease	disease	NOUN
fnp-5848	41	38	(	(	PUNCT
fnp-5848	41	39	pd	pd	NOUN
fnp-5848	41	40	)	)	PUNCT
fnp-5848	41	41	when	when	SCONJ
fnp-5848	41	42	localized	localize	VERB
fnp-5848	41	43	to	to	ADP
fnp-5848	41	44	the	the	DET
fnp-5848	41	45	substantia	substantia	NOUN
fnp-5848	41	46	nigra	nigra	NOUN
fnp-5848	41	47	,	,	PUNCT
fnp-5848	41	48	but	but	CCONJ
fnp-5848	41	49	they	they	PRON
fnp-5848	41	50	can	can	AUX
fnp-5848	41	51	progress	progress	VERB
fnp-5848	41	52	to	to	ADP
fnp-5848	41	53	a	a	DET
fnp-5848	41	54	diffuse	diffuse	NOUN
fnp-5848	41	55	pattern	pattern	NOUN
fnp-5848	41	56	leading	lead	VERB
fnp-5848	41	57	to	to	ADP
fnp-5848	41	58	parkinson	parkinson	NOUN
fnp-5848	41	59	's	's	PART
fnp-5848	41	60	disease	disease	NOUN
fnp-5848	41	61	dementia	dementia	NOUN
fnp-5848	41	62	(	(	PUNCT
fnp-5848	41	63	pdd	pdd	NOUN
fnp-5848	41	64	)	)	PUNCT
fnp-5848	41	65	.	.	PUNCT
fnp-5848	42	1	when	when	SCONJ
fnp-5848	42	2	lewy	lewy	PROPN
fnp-5848	42	3	bodies	body	NOUN
fnp-5848	42	4	are	be	AUX
fnp-5848	42	5	found	find	VERB
fnp-5848	42	6	in	in	ADP
fnp-5848	42	7	the	the	DET
fnp-5848	42	8	neocortex	neocortex	NOUN
fnp-5848	42	9	and	and	CCONJ
fnp-5848	42	10	associated	associate	VERB
fnp-5848	42	11	with	with	ADP
fnp-5848	42	12	dementia	dementia	NOUN
fnp-5848	42	13	as	as	ADP
fnp-5848	42	14	the	the	DET
fnp-5848	42	15	presenting	presenting	NOUN
fnp-5848	42	16	symptom	symptom	NOUN
fnp-5848	42	17	,	,	PUNCT
fnp-5848	42	18	this	this	DET
fnp-5848	42	19	condition	condition	NOUN
fnp-5848	42	20	is	be	AUX
fnp-5848	42	21	termed	term	VERB
fnp-5848	42	22	diffuse	diffuse	PROPN
fnp-5848	42	23	lewy	lewy	ADJ
fnp-5848	42	24	body	body	NOUN
fnp-5848	42	25	disease	disease	NOUN
fnp-5848	42	26	(	(	PUNCT
fnp-5848	42	27	dlbd	dlbd	PROPN
fnp-5848	42	28	)	)	PUNCT
fnp-5848	42	29	.	.	PUNCT
fnp-5848	43	1	in	in	ADP
fnp-5848	43	2	patients	patient	NOUN
fnp-5848	43	3	with	with	ADP
fnp-5848	43	4	dlbd	dlbd	NOUN
fnp-5848	43	5	,	,	PUNCT
fnp-5848	43	6	extrapyramidal	extrapyramidal	ADJ
fnp-5848	43	7	parkinsonian	parkinsonian	ADJ
fnp-5848	43	8	features	feature	VERB
fnp-5848	43	9	may	may	AUX
fnp-5848	43	10	or	or	CCONJ
fnp-5848	43	11	may	may	AUX
fnp-5848	43	12	not	not	PART
fnp-5848	43	13	develop	develop	VERB
fnp-5848	43	14	.	.	PUNCT
fnp-5848	44	1	lewy	lewy	PROPN
fnp-5848	44	2	bodies	body	NOUN
fnp-5848	44	3	are	be	AUX
fnp-5848	44	4	also	also	ADV
fnp-5848	44	5	seen	see	VERB
fnp-5848	44	6	in	in	ADP
fnp-5848	44	7	alzheimer	alzheimer	PROPN
fnp-5848	44	8	's	's	PART
fnp-5848	44	9	disease	disease	NOUN
fnp-5848	44	10	(	(	PUNCT
fnp-5848	44	11	ad	ad	NOUN
fnp-5848	44	12	)	)	PUNCT
fnp-5848	44	13	.	.	PUNCT
fnp-5848	45	1	however	however	ADV
fnp-5848	45	2	,	,	PUNCT
fnp-5848	45	3	the	the	DET
fnp-5848	45	4	extent	extent	NOUN
fnp-5848	45	5	to	to	PART
fnp-5848	45	6	which	which	PRON
fnp-5848	45	7	the	the	DET
fnp-5848	45	8	rates	rate	NOUN
fnp-5848	45	9	of	of	ADP
fnp-5848	45	10	extrapyramidal	extrapyramidal	ADJ
fnp-5848	45	11	motor	motor	NOUN
fnp-5848	45	12	decline	decline	NOUN
fnp-5848	45	13	progress	progress	NOUN
fnp-5848	45	14	in	in	ADP
fnp-5848	45	15	these	these	DET
fnp-5848	45	16	different	different	ADJ
fnp-5848	45	17	contexts	contexts	NOUN
fnp-5848	45	18	is	be	AUX
fnp-5848	45	19	unclear	unclear	ADJ
fnp-5848	45	20	due	due	ADP
fnp-5848	45	21	to	to	ADP
fnp-5848	45	22	the	the	DET
fnp-5848	45	23	limited	limited	ADJ
fnp-5848	45	24	number	number	NOUN
fnp-5848	45	25	of	of	ADP
fnp-5848	45	26	longitudinal	longitudinal	ADJ
fnp-5848	45	27	studies	study	NOUN
fnp-5848	45	28	with	with	ADP
fnp-5848	45	29	neuropathological	neuropathological	ADJ
fnp-5848	45	30	endpoints	endpoint	NOUN
fnp-5848	45	31	,	,	PUNCT
fnp-5848	45	32	which	which	PRON
fnp-5848	45	33	are	be	AUX
fnp-5848	45	34	crucial	crucial	ADJ
fnp-5848	45	35	for	for	ADP
fnp-5848	45	36	prognostication	prognostication	NOUN
fnp-5848	45	37	,	,	PUNCT
fnp-5848	45	38	clinical	clinical	ADJ
fnp-5848	45	39	trial	trial	NOUN
fnp-5848	45	40	design	design	NOUN
fnp-5848	45	41	,	,	PUNCT
fnp-5848	45	42	and	and	CCONJ
fnp-5848	45	43	further	further	ADJ
fnp-5848	45	44	research	research	NOUN
fnp-5848	45	45	.	.	PUNCT
fnp-5848	46	1	a	a	DET
fnp-5848	46	2	study	study	NOUN
fnp-5848	46	3	by	by	ADP
fnp-5848	46	4	choudhury	choudhury	PROPN
fnp-5848	46	5	et	et	PROPN
fnp-5848	46	6	al	al	PROPN
fnp-5848	46	7	.	.	PROPN
fnp-5848	46	8	published	publish	VERB
fnp-5848	46	9	in	in	ADP
fnp-5848	46	10	alzheimer	alzheimer	PROPN
fnp-5848	46	11	’s	’s	PART
fnp-5848	46	12	&	&	CCONJ
fnp-5848	46	13	dementia	dementia	PROPN
fnp-5848	46	14	investigates	investigate	VERB
fnp-5848	46	15	the	the	DET
fnp-5848	46	16	progression	progression	NOUN
fnp-5848	46	17	of	of	ADP
fnp-5848	46	18	motor	motor	NOUN
fnp-5848	46	19	deficits	deficit	NOUN
fnp-5848	46	20	in	in	ADP
fnp-5848	46	21	dementia	dementia	NOUN
fnp-5848	46	22	with	with	ADP
fnp-5848	46	23	lewy	lewy	ADJ
fnp-5848	46	24	bodies	body	NOUN
fnp-5848	46	25	(	(	PUNCT
fnp-5848	46	26	dlb	dlb	PROPN
fnp-5848	46	27	)	)	PUNCT
fnp-5848	46	28	,	,	PUNCT
fnp-5848	46	29	parkinson	parkinson	NOUN
fnp-5848	46	30	’s	’s	PART
fnp-5848	46	31	disease	disease	NOUN
fnp-5848	46	32	dementia	dementia	NOUN
fnp-5848	46	33	(	(	PUNCT
fnp-5848	46	34	pdd	pdd	NOUN
fnp-5848	46	35	)	)	PUNCT
fnp-5848	46	36	,	,	PUNCT
fnp-5848	46	37	and	and	CCONJ
fnp-5848	46	38	alzheimer	alzheimer	PROPN
fnp-5848	46	39	’s	’s	PART
fnp-5848	46	40	disease	disease	NOUN
fnp-5848	46	41	dementia	dementia	NOUN
fnp-5848	46	42	(	(	PUNCT
fnp-5848	46	43	ad	ad	NOUN
fnp-5848	46	44	)	)	PUNCT
fnp-5848	46	45	using	use	VERB
fnp-5848	46	46	data	datum	NOUN
fnp-5848	46	47	from	from	ADP
fnp-5848	46	48	the	the	DET
fnp-5848	46	49	arizona	arizona	PROPN
fnp-5848	46	50	study	study	NOUN
fnp-5848	46	51	of	of	ADP
fnp-5848	46	52	aging	age	VERB
fnp-5848	46	53	and	and	CCONJ
fnp-5848	46	54	neurodegenerative	neurodegenerative	ADJ
fnp-5848	46	55	disorders	disorder	NOUN
fnp-5848	46	56	(	(	PUNCT
fnp-5848	46	57	choudhury	choudhury	PROPN
fnp-5848	46	58	et	et	PROPN
fnp-5848	46	59	al	al	PROPN
fnp-5848	46	60	.	.	PROPN
fnp-5848	46	61	,	,	PUNCT
fnp-5848	46	62	2023	2023	NUM
fnp-5848	46	63	)	)	PUNCT
fnp-5848	46	64	.	.	PUNCT
fnp-5848	47	1	the	the	DET
fnp-5848	47	2	study	study	NOUN
fnp-5848	47	3	included	include	VERB
fnp-5848	47	4	193	193	NUM
fnp-5848	47	5	participants	participant	NOUN
fnp-5848	47	6	with	with	ADP
fnp-5848	47	7	autopsy	autopsy	NOUN
fnp-5848	47	8	-	-	PUNCT
fnp-5848	47	9	confirmed	confirm	VERB
fnp-5848	47	10	diagnoses	diagnosis	NOUN
fnp-5848	47	11	:	:	PUNCT
fnp-5848	47	12	98	98	NUM
fnp-5848	47	13	with	with	ADP
fnp-5848	47	14	pdd	pdd	NOUN
fnp-5848	47	15	,	,	PUNCT
fnp-5848	47	16	48	48	NUM
fnp-5848	47	17	with	with	ADP
fnp-5848	47	18	dlb	dlb	NOUN
fnp-5848	47	19	,	,	PUNCT
fnp-5848	47	20	and	and	CCONJ
fnp-5848	47	21	47	47	NUM
fnp-5848	47	22	with	with	ADP
fnp-5848	47	23	ad	ad	NOUN
fnp-5848	47	24	.	.	PUNCT
fnp-5848	48	1	within	within	ADP
fnp-5848	48	2	the	the	DET
fnp-5848	48	3	dlb	dlb	NOUN
fnp-5848	48	4	cohort	cohort	NOUN
fnp-5848	48	5	,	,	PUNCT
fnp-5848	48	6	participants	participant	NOUN
fnp-5848	48	7	were	be	AUX
fnp-5848	48	8	further	far	ADV
fnp-5848	48	9	categorized	categorize	VERB
fnp-5848	48	10	into	into	ADP
fnp-5848	48	11	those	those	PRON
fnp-5848	48	12	with	with	ADP
fnp-5848	48	13	parkinsonism	parkinsonism	NOUN
fnp-5848	48	14	(	(	PUNCT
fnp-5848	48	15	dlb+	dlb+	NOUN
fnp-5848	48	16	)	)	PUNCT
fnp-5848	48	17	and	and	CCONJ
fnp-5848	48	18	without	without	ADP
fnp-5848	48	19	parkinsonism	parkinsonism	NOUN
fnp-5848	48	20	(	(	PUNCT
fnp-5848	48	21	dlb-	dlb-	ADJ
fnp-5848	48	22	)	)	PUNCT
fnp-5848	48	23	.	.	PUNCT
fnp-5848	49	1	the	the	DET
fnp-5848	49	2	researchers	researcher	NOUN
fnp-5848	49	3	utilized	utilize	VERB
fnp-5848	49	4	the	the	DET
fnp-5848	49	5	unified	unified	ADJ
fnp-5848	49	6	parkinson	parkinson	NOUN
fnp-5848	49	7	’s	’s	PART
fnp-5848	49	8	disease	disease	NOUN
fnp-5848	49	9	rating	rating	NOUN
fnp-5848	49	10	scale	scale	NOUN
fnp-5848	49	11	(	(	PUNCT
fnp-5848	49	12	updrs	updrs	PROPN
fnp-5848	49	13	)	)	PUNCT
fnp-5848	49	14	parts	part	NOUN
fnp-5848	49	15	ii	ii	PROPN
fnp-5848	49	16	and	and	CCONJ
fnp-5848	49	17	iii	iii	NOUN
fnp-5848	49	18	to	to	PART
fnp-5848	49	19	assess	assess	VERB
fnp-5848	49	20	motor	motor	NOUN
fnp-5848	49	21	function	function	NOUN
fnp-5848	49	22	over	over	ADP
fnp-5848	49	23	an	an	DET
fnp-5848	49	24	eight	eight	NUM
fnp-5848	49	25	-	-	PUNCT
fnp-5848	49	26	year	year	NOUN
fnp-5848	49	27	period	period	NOUN
fnp-5848	49	28	,	,	PUNCT
fnp-5848	49	29	employing	employ	VERB
fnp-5848	49	30	non	non	ADJ
fnp-5848	49	31	-	-	ADJ
fnp-5848	49	32	linear	linear	ADJ
fnp-5848	49	33	mixed	mixed	ADJ
fnp-5848	49	34	effects	effect	NOUN
fnp-5848	49	35	models	model	NOUN
fnp-5848	49	36	to	to	PART
fnp-5848	49	37	analyze	analyze	VERB
fnp-5848	49	38	the	the	DET
fnp-5848	49	39	data	datum	NOUN
fnp-5848	49	40	.	.	PUNCT
fnp-5848	50	1	the	the	DET
fnp-5848	50	2	results	result	NOUN
fnp-5848	50	3	revealed	reveal	VERB
fnp-5848	50	4	that	that	SCONJ
fnp-5848	50	5	motor	motor	NOUN
fnp-5848	50	6	deficits	deficit	NOUN
fnp-5848	50	7	progressed	progress	VERB
fnp-5848	50	8	most	most	ADV
fnp-5848	50	9	rapidly	rapidly	ADV
fnp-5848	50	10	https://doi.org/10.17879/freeneuropathology-2024free	https://doi.org/10.17879/freeneuropathology-2024free	NUM
fnp-5848	50	11	neuropathology	neuropathology	NOUN
fnp-5848	50	12	5:31	5:31	NUM
fnp-5848	50	13	(	(	PUNCT
fnp-5848	50	14	2024	2024	NUM
fnp-5848	50	15	)	)	PUNCT
fnp-5848	50	16	john	john	PROPN
fnp-5848	50	17	f.	f.	PROPN
fnp-5848	50	18	crary	crary	PROPN
fnp-5848	50	19	doi	doi	PROPN
fnp-5848	50	20	:	:	PUNCT
fnp-5848	50	21	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	50	22	page	page	NOUN
fnp-5848	50	23	4	4	NUM
fnp-5848	50	24	of	of	ADP
fnp-5848	50	25	12	12	NUM
fnp-5848	50	26	in	in	ADP
fnp-5848	50	27	the	the	DET
fnp-5848	50	28	dlb+	dlb+	NOUN
fnp-5848	50	29	group	group	NOUN
fnp-5848	50	30	,	,	PUNCT
fnp-5848	50	31	with	with	ADP
fnp-5848	50	32	significant	significant	ADJ
fnp-5848	50	33	worsening	worsening	NOUN
fnp-5848	50	34	in	in	ADP
fnp-5848	50	35	gait	gait	NOUN
fnp-5848	50	36	and	and	CCONJ
fnp-5848	50	37	limb	limb	PROPN
fnp-5848	50	38	bradykinesia	bradykinesia	NOUN
fnp-5848	50	39	compared	compare	VERB
fnp-5848	50	40	to	to	ADP
fnp-5848	50	41	pdd	pdd	NOUN
fnp-5848	50	42	and	and	CCONJ
fnp-5848	50	43	other	other	ADJ
fnp-5848	50	44	groups	group	NOUN
fnp-5848	50	45	(	(	PUNCT
fnp-5848	50	46	figure	figure	NOUN
fnp-5848	50	47	 	 	SPACE
fnp-5848	50	48	2	2	NUM
fnp-5848	50	49	)	)	PUNCT
fnp-5848	50	50	.	.	PUNCT
fnp-5848	51	1	the	the	DET
fnp-5848	51	2	study	study	NOUN
fnp-5848	51	3	found	find	VERB
fnp-5848	51	4	that	that	SCONJ
fnp-5848	51	5	baseline	baseline	VERB
fnp-5848	51	6	updrs	updr	NOUN
fnp-5848	51	7	-	-	NOUN
fnp-5848	51	8	ii	ii	NOUN
fnp-5848	51	9	and	and	CCONJ
fnp-5848	51	10	iii	iii	NUM
fnp-5848	51	11	scores	score	NOUN
fnp-5848	51	12	were	be	AUX
fnp-5848	51	13	highest	high	ADJ
fnp-5848	51	14	in	in	ADP
fnp-5848	51	15	the	the	DET
fnp-5848	51	16	pdd	pdd	NOUN
fnp-5848	51	17	group	group	NOUN
fnp-5848	51	18	,	,	PUNCT
fnp-5848	51	19	followed	follow	VERB
fnp-5848	51	20	by	by	ADP
fnp-5848	51	21	dlb+	dlb+	PROPN
fnp-5848	51	22	,	,	PUNCT
fnp-5848	51	23	ad	ad	NOUN
fnp-5848	51	24	,	,	PUNCT
fnp-5848	51	25	and	and	CCONJ
fnp-5848	51	26	dlb-	dlb-	ADJ
fnp-5848	51	27	.	.	PUNCT
fnp-5848	52	1	over	over	ADP
fnp-5848	52	2	time	time	NOUN
fnp-5848	52	3	,	,	PUNCT
fnp-5848	52	4	the	the	DET
fnp-5848	52	5	dlb+	dlb+	PROPN
fnp-5848	52	6	group	group	NOUN
fnp-5848	52	7	showed	show	VERB
fnp-5848	52	8	a	a	DET
fnp-5848	52	9	faster	fast	ADJ
fnp-5848	52	10	progression	progression	NOUN
fnp-5848	52	11	in	in	ADP
fnp-5848	52	12	updrs	updr	NOUN
fnp-5848	52	13	-	-	NOUN
fnp-5848	52	14	iii	iii	NUM
fnp-5848	52	15	scores	score	NOUN
fnp-5848	52	16	compared	compare	VERB
fnp-5848	52	17	to	to	ADP
fnp-5848	52	18	pdd	pdd	NOUN
fnp-5848	52	19	,	,	PUNCT
fnp-5848	52	20	driven	drive	VERB
fnp-5848	52	21	by	by	ADP
fnp-5848	52	22	significant	significant	ADJ
fnp-5848	52	23	declines	decline	NOUN
fnp-5848	52	24	in	in	ADP
fnp-5848	52	25	gait	gait	NOUN
fnp-5848	52	26	and	and	CCONJ
fnp-5848	52	27	limb	limb	PROPN
fnp-5848	52	28	bradykinesia	bradykinesia	PROPN
fnp-5848	52	29	.	.	PUNCT
fnp-5848	53	1	the	the	DET
fnp-5848	53	2	study	study	NOUN
fnp-5848	53	3	also	also	ADV
fnp-5848	53	4	highlighted	highlight	VERB
fnp-5848	53	5	that	that	SCONJ
fnp-5848	53	6	the	the	DET
fnp-5848	53	7	presence	presence	NOUN
fnp-5848	53	8	of	of	ADP
fnp-5848	53	9	parkinsonism	parkinsonism	NOUN
fnp-5848	53	10	in	in	ADP
fnp-5848	53	11	dlb	dlb	PROPN
fnp-5848	53	12	(	(	PUNCT
fnp-5848	53	13	dlb+	dlb+	PROPN
fnp-5848	53	14	)	)	PUNCT
fnp-5848	53	15	was	be	AUX
fnp-5848	53	16	associated	associate	VERB
fnp-5848	53	17	with	with	ADP
fnp-5848	53	18	more	more	ADV
fnp-5848	53	19	rapid	rapid	ADJ
fnp-5848	53	20	motor	motor	NOUN
fnp-5848	53	21	decline	decline	NOUN
fnp-5848	53	22	than	than	ADP
fnp-5848	53	23	in	in	ADP
fnp-5848	53	24	dlbor	dlbor	NOUN
fnp-5848	53	25	ad	ad	NOUN
fnp-5848	53	26	,	,	PUNCT
fnp-5848	53	27	emphasizing	emphasize	VERB
fnp-5848	53	28	the	the	DET
fnp-5848	53	29	importance	importance	NOUN
fnp-5848	53	30	of	of	ADP
fnp-5848	53	31	recognizing	recognize	VERB
fnp-5848	53	32	and	and	CCONJ
fnp-5848	53	33	monitoring	monitor	VERB
fnp-5848	53	34	these	these	DET
fnp-5848	53	35	symptoms	symptom	NOUN
fnp-5848	53	36	for	for	ADP
fnp-5848	53	37	better	well	ADJ
fnp-5848	53	38	clinical	clinical	ADJ
fnp-5848	53	39	management	management	NOUN
fnp-5848	53	40	and	and	CCONJ
fnp-5848	53	41	prognostication	prognostication	NOUN
fnp-5848	53	42	.	.	PUNCT
fnp-5848	54	1	the	the	DET
fnp-5848	54	2	findings	finding	NOUN
fnp-5848	54	3	underscore	underscore	VERB
fnp-5848	54	4	the	the	DET
fnp-5848	54	5	need	need	NOUN
fnp-5848	54	6	for	for	ADP
fnp-5848	54	7	targeted	target	VERB
fnp-5848	54	8	interventions	intervention	NOUN
fnp-5848	54	9	to	to	PART
fnp-5848	54	10	address	address	VERB
fnp-5848	54	11	motor	motor	NOUN
fnp-5848	54	12	deficits	deficit	NOUN
fnp-5848	54	13	and	and	CCONJ
fnp-5848	54	14	suggest	suggest	VERB
fnp-5848	54	15	that	that	SCONJ
fnp-5848	54	16	patients	patient	NOUN
fnp-5848	54	17	may	may	AUX
fnp-5848	54	18	benefit	benefit	VERB
fnp-5848	54	19	from	from	ADP
fnp-5848	54	20	specific	specific	ADJ
fnp-5848	54	21	therapeutic	therapeutic	ADJ
fnp-5848	54	22	strategies	strategy	NOUN
fnp-5848	54	23	aimed	aim	VERB
fnp-5848	54	24	at	at	ADP
fnp-5848	54	25	mitigating	mitigate	VERB
fnp-5848	54	26	motor	motor	NOUN
fnp-5848	54	27	decline	decline	NOUN
fnp-5848	54	28	.	.	PUNCT
fnp-5848	55	1	the	the	DET
fnp-5848	55	2	research	research	NOUN
fnp-5848	55	3	provides	provide	VERB
fnp-5848	55	4	valuable	valuable	ADJ
fnp-5848	55	5	insights	insight	NOUN
fnp-5848	55	6	into	into	ADP
fnp-5848	55	7	the	the	DET
fnp-5848	55	8	differential	differential	ADJ
fnp-5848	55	9	progression	progression	NOUN
fnp-5848	55	10	of	of	ADP
fnp-5848	55	11	motor	motor	NOUN
fnp-5848	55	12	impairments	impairment	NOUN
fnp-5848	55	13	in	in	ADP
fnp-5848	55	14	neurodegenerative	neurodegenerative	ADJ
fnp-5848	55	15	dementias	dementia	NOUN
fnp-5848	55	16	,	,	PUNCT
fnp-5848	55	17	with	with	ADP
fnp-5848	55	18	implications	implication	NOUN
fnp-5848	55	19	for	for	ADP
fnp-5848	55	20	clinical	clinical	ADJ
fnp-5848	55	21	trial	trial	NOUN
fnp-5848	55	22	design	design	NOUN
fnp-5848	55	23	and	and	CCONJ
fnp-5848	55	24	patient	patient	ADJ
fnp-5848	55	25	care	care	NOUN
fnp-5848	55	26	.	.	PUNCT
fnp-5848	56	1	figure	figure	NOUN
fnp-5848	56	2	 	 	SPACE
fnp-5848	56	3	2	2	NUM
fnp-5848	56	4	.	.	PUNCT
fnp-5848	56	5	updrs	updrs	PROPN
fnp-5848	56	6	-	-	NOUN
fnp-5848	56	7	iii	iii	NUM
fnp-5848	56	8	total	total	ADJ
fnp-5848	56	9	scores	score	NOUN
fnp-5848	56	10	during	during	ADP
fnp-5848	56	11	off	off	ADP
fnp-5848	56	12	stage	stage	NOUN
fnp-5848	56	13	examination	examination	NOUN
fnp-5848	56	14	for	for	ADP
fnp-5848	56	15	each	each	DET
fnp-5848	56	16	participant	participant	NOUN
fnp-5848	56	17	and	and	CCONJ
fnp-5848	56	18	their	their	PRON
fnp-5848	56	19	trajectories	trajectory	NOUN
fnp-5848	56	20	for	for	ADP
fnp-5848	56	21	groups	group	NOUN
fnp-5848	56	22	:	:	PUNCT
fnp-5848	56	23	pdd	pdd	X
fnp-5848	56	24	(	(	PUNCT
fnp-5848	56	25	a	a	NOUN
fnp-5848	56	26	)	)	PUNCT
fnp-5848	56	27	,	,	PUNCT
fnp-5848	56	28	dlb+	dlb+	PROPN
fnp-5848	56	29	(	(	PUNCT
fnp-5848	56	30	b	b	NOUN
fnp-5848	56	31	)	)	PUNCT
fnp-5848	56	32	,	,	PUNCT
fnp-5848	56	33	dlb−	dlb−	PROPN
fnp-5848	56	34	(	(	PUNCT
fnp-5848	56	35	c	c	NOUN
fnp-5848	56	36	)	)	PUNCT
fnp-5848	56	37	,	,	PUNCT
fnp-5848	56	38	and	and	CCONJ
fnp-5848	56	39	ad	ad	NOUN
fnp-5848	56	40	(	(	PUNCT
fnp-5848	56	41	d	d	NOUN
fnp-5848	56	42	)	)	PUNCT
fnp-5848	56	43	.	.	PUNCT
fnp-5848	57	1	each	each	DET
fnp-5848	57	2	point	point	NOUN
fnp-5848	57	3	represents	represent	VERB
fnp-5848	57	4	one	one	NUM
fnp-5848	57	5	movement	movement	NOUN
fnp-5848	57	6	exam	exam	NOUN
fnp-5848	57	7	visit	visit	NOUN
fnp-5848	57	8	and	and	CCONJ
fnp-5848	57	9	corresponding	correspond	VERB
fnp-5848	57	10	score	score	NOUN
fnp-5848	57	11	.	.	PUNCT
fnp-5848	58	1	blue	blue	ADJ
fnp-5848	58	2	lines	line	NOUN
fnp-5848	58	3	depict	depict	VERB
fnp-5848	58	4	each	each	DET
fnp-5848	58	5	participant	participant	NOUN
fnp-5848	58	6	.	.	PUNCT
fnp-5848	59	1	red	red	ADJ
fnp-5848	59	2	line	line	NOUN
fnp-5848	59	3	represents	represent	VERB
fnp-5848	59	4	a	a	DET
fnp-5848	59	5	mixed	mixed	ADJ
fnp-5848	59	6	model	model	NOUN
fnp-5848	59	7	fit	fit	ADJ
fnp-5848	59	8	line	line	NOUN
fnp-5848	59	9	.	.	PUNCT
fnp-5848	60	1	the	the	DET
fnp-5848	60	2	shaded	shaded	ADJ
fnp-5848	60	3	area	area	NOUN
fnp-5848	60	4	(	(	PUNCT
fnp-5848	60	5	funnel	funnel	NOUN
fnp-5848	60	6	)	)	PUNCT
fnp-5848	60	7	surrounding	surround	VERB
fnp-5848	60	8	red	red	ADJ
fnp-5848	60	9	fit	fit	ADJ
fnp-5848	60	10	line	line	NOUN
fnp-5848	60	11	represents	represent	VERB
fnp-5848	60	12	95	95	NUM
fnp-5848	60	13	 	 	SPACE
fnp-5848	60	14	%	%	NOUN
fnp-5848	60	15	confidence	confidence	NOUN
fnp-5848	60	16	interval	interval	NOUN
fnp-5848	60	17	for	for	ADP
fnp-5848	60	18	the	the	DET
fnp-5848	60	19	mixed	mixed	ADJ
fnp-5848	60	20	model	model	NOUN
fnp-5848	60	21	fitted	fit	VERB
fnp-5848	60	22	curves	curve	NOUN
fnp-5848	60	23	.	.	PUNCT
fnp-5848	61	1	ad	ad	NOUN
fnp-5848	61	2	,	,	PUNCT
fnp-5848	61	3	alzheimer	alzheimer	PROPN
fnp-5848	61	4	’s	’s	PART
fnp-5848	61	5	disease	disease	NOUN
fnp-5848	61	6	;	;	PUNCT
fnp-5848	61	7	dlb+	dlb+	PROPN
fnp-5848	61	8	,	,	PUNCT
fnp-5848	61	9	dlb	dlb	NOUN
fnp-5848	61	10	with	with	ADP
fnp-5848	61	11	parkinsonism	parkinsonism	NOUN
fnp-5848	61	12	;	;	PUNCT
fnp-5848	61	13	dlb−	dlb−	PROPN
fnp-5848	61	14	,	,	PUNCT
fnp-5848	61	15	dlb	dlb	NOUN
fnp-5848	61	16	without	without	ADP
fnp-5848	61	17	parkinsonism	parkinsonism	NOUN
fnp-5848	61	18	;	;	PUNCT
fnp-5848	61	19	dlb	dlb	PROPN
fnp-5848	61	20	,	,	PUNCT
fnp-5848	61	21	dementia	dementia	NOUN
fnp-5848	61	22	with	with	ADP
fnp-5848	61	23	lewy	lewy	PROPN
fnp-5848	61	24	bodies	body	NOUN
fnp-5848	61	25	;	;	PUNCT
fnp-5848	61	26	pdd	pdd	NOUN
fnp-5848	61	27	,	,	PUNCT
fnp-5848	61	28	parkinson	parkinson	NOUN
fnp-5848	61	29	’s	’s	PART
fnp-5848	61	30	disease	disease	NOUN
fnp-5848	61	31	dementia	dementia	NOUN
fnp-5848	61	32	.	.	PUNCT
fnp-5848	62	1	reproduced	reproduce	VERB
fnp-5848	62	2	with	with	ADP
fnp-5848	62	3	modifications	modification	NOUN
fnp-5848	62	4	under	under	ADP
fnp-5848	62	5	the	the	DET
fnp-5848	62	6	terms	term	NOUN
fnp-5848	62	7	of	of	ADP
fnp-5848	62	8	the	the	DET
fnp-5848	62	9	cc	cc	NOUN
fnp-5848	62	10	-	-	PUNCT
fnp-5848	62	11	by	by	ADJ
fnp-5848	62	12	license	license	NOUN
fnp-5848	62	13	(	(	PUNCT
fnp-5848	62	14	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	62	15	)	)	PUNCT
fnp-5848	62	16	.	.	PUNCT
fnp-5848	63	1	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	63	2	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	63	3	free	free	ADJ
fnp-5848	63	4	neuropathology	neuropathology	NOUN
fnp-5848	63	5	5:31	5:31	NUM
fnp-5848	63	6	(	(	PUNCT
fnp-5848	63	7	2024	2024	NUM
fnp-5848	63	8	)	)	PUNCT
fnp-5848	63	9	john	john	PROPN
fnp-5848	63	10	f.	f.	PROPN
fnp-5848	63	11	crary	crary	PROPN
fnp-5848	63	12	doi	doi	PROPN
fnp-5848	63	13	:	:	PUNCT
fnp-5848	63	14	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	63	15	page	page	NOUN
fnp-5848	63	16	5	5	NUM
fnp-5848	63	17	of	of	ADP
fnp-5848	63	18	12	12	NUM
fnp-5848	63	19	4	4	NUM
fnp-5848	63	20	.	.	PUNCT
fnp-5848	63	21	 	 	SPACE
fnp-5848	63	22	cell	cell	NOUN
fnp-5848	63	23	-	-	PUNCT
fnp-5848	63	24	type	type	NOUN
fnp-5848	63	25	-	-	PUNCT
fnp-5848	63	26	specific	specific	ADJ
fnp-5848	63	27	alzheimer	alzheimer	NOUN
fnp-5848	63	28	’s	’s	PART
fnp-5848	63	29	polygenic	polygenic	ADJ
fnp-5848	63	30	risk	risk	NOUN
fnp-5848	63	31	scores	score	VERB
fnp-5848	63	32	large	large	ADJ
fnp-5848	63	33	-	-	PUNCT
fnp-5848	63	34	scale	scale	NOUN
fnp-5848	63	35	genetic	genetic	ADJ
fnp-5848	63	36	studies	study	NOUN
fnp-5848	63	37	have	have	AUX
fnp-5848	63	38	uncovered	uncover	VERB
fnp-5848	63	39	numerous	numerous	ADJ
fnp-5848	63	40	genetic	genetic	ADJ
fnp-5848	63	41	loci	loci	NOUN
fnp-5848	63	42	associated	associate	VERB
fnp-5848	63	43	with	with	ADP
fnp-5848	63	44	alzheimer	alzheimer	PROPN
fnp-5848	63	45	's	's	PART
fnp-5848	63	46	disease	disease	NOUN
fnp-5848	63	47	(	(	PUNCT
fnp-5848	63	48	ad	ad	NOUN
fnp-5848	63	49	)	)	PUNCT
fnp-5848	63	50	,	,	PUNCT
fnp-5848	63	51	but	but	CCONJ
fnp-5848	63	52	understanding	understand	VERB
fnp-5848	63	53	how	how	SCONJ
fnp-5848	63	54	the	the	DET
fnp-5848	63	55	corresponding	corresponding	ADJ
fnp-5848	63	56	causal	causal	ADJ
fnp-5848	63	57	genes	gene	NOUN
fnp-5848	63	58	contribute	contribute	VERB
fnp-5848	63	59	to	to	ADP
fnp-5848	63	60	the	the	DET
fnp-5848	63	61	cellular	cellular	ADJ
fnp-5848	63	62	and	and	CCONJ
fnp-5848	63	63	molecular	molecular	ADJ
fnp-5848	63	64	mechanisms	mechanism	NOUN
fnp-5848	63	65	driving	drive	VERB
fnp-5848	63	66	ad	ad	NOUN
fnp-5848	63	67	remains	remain	VERB
fnp-5848	63	68	a	a	DET
fnp-5848	63	69	major	major	ADJ
fnp-5848	63	70	challenge	challenge	NOUN
fnp-5848	63	71	.	.	PUNCT
fnp-5848	64	1	since	since	SCONJ
fnp-5848	64	2	neurodegeneration	neurodegeneration	NOUN
fnp-5848	64	3	in	in	ADP
fnp-5848	64	4	ad	ad	NOUN
fnp-5848	64	5	is	be	AUX
fnp-5848	64	6	a	a	DET
fnp-5848	64	7	complex	complex	ADJ
fnp-5848	64	8	,	,	PUNCT
fnp-5848	64	9	non	non	ADJ
fnp-5848	64	10	-	-	ADJ
fnp-5848	64	11	cell	cell	ADJ
fnp-5848	64	12	autonomous	autonomous	ADJ
fnp-5848	64	13	process	process	NOUN
fnp-5848	64	14	involving	involve	VERB
fnp-5848	64	15	interactions	interaction	NOUN
fnp-5848	64	16	between	between	ADP
fnp-5848	64	17	multiple	multiple	ADJ
fnp-5848	64	18	cell	cell	NOUN
fnp-5848	64	19	types	type	NOUN
fnp-5848	64	20	,	,	PUNCT
fnp-5848	64	21	deciphering	decipher	VERB
fnp-5848	64	22	how	how	SCONJ
fnp-5848	64	23	these	these	DET
fnp-5848	64	24	genes	gene	NOUN
fnp-5848	64	25	act	act	VERB
fnp-5848	64	26	across	across	ADP
fnp-5848	64	27	different	different	ADJ
fnp-5848	64	28	cells	cell	NOUN
fnp-5848	64	29	is	be	AUX
fnp-5848	64	30	essential	essential	ADJ
fnp-5848	64	31	for	for	ADP
fnp-5848	64	32	identifying	identify	VERB
fnp-5848	64	33	therapeutic	therapeutic	ADJ
fnp-5848	64	34	targets	target	NOUN
fnp-5848	64	35	.	.	PUNCT
fnp-5848	65	1	genes	gene	NOUN
fnp-5848	65	2	expressed	express	VERB
fnp-5848	65	3	by	by	ADP
fnp-5848	65	4	microglia	microglia	NOUN
fnp-5848	65	5	and	and	CCONJ
fnp-5848	65	6	astrocytes	astrocyte	NOUN
fnp-5848	65	7	are	be	AUX
fnp-5848	65	8	notably	notably	ADV
fnp-5848	65	9	over	over	ADV
fnp-5848	65	10	-	-	PUNCT
fnp-5848	65	11	represented	represent	VERB
fnp-5848	65	12	in	in	ADP
fnp-5848	65	13	genome	genome	NOUN
fnp-5848	65	14	-	-	PUNCT
fnp-5848	65	15	wide	wide	ADJ
fnp-5848	65	16	association	association	NOUN
fnp-5848	65	17	studies	study	NOUN
fnp-5848	65	18	(	(	PUNCT
fnp-5848	65	19	gwas	gwas	PROPN
fnp-5848	65	20	)	)	PUNCT
fnp-5848	65	21	of	of	ADP
fnp-5848	65	22	ad	ad	NOUN
fnp-5848	65	23	.	.	PUNCT
fnp-5848	66	1	however	however	ADV
fnp-5848	66	2	,	,	PUNCT
fnp-5848	66	3	how	how	SCONJ
fnp-5848	66	4	these	these	DET
fnp-5848	66	5	cell	cell	NOUN
fnp-5848	66	6	-	-	PUNCT
fnp-5848	66	7	specific	specific	ADJ
fnp-5848	66	8	genetic	genetic	ADJ
fnp-5848	66	9	changes	change	NOUN
fnp-5848	66	10	connect	connect	VERB
fnp-5848	66	11	to	to	ADP
fnp-5848	66	12	the	the	DET
fnp-5848	66	13	neuropatholo	neuropatholo	ADJ
fnp-5848	66	14	gical	gical	ADJ
fnp-5848	66	15	hallmarks	hallmark	NOUN
fnp-5848	66	16	of	of	ADP
fnp-5848	66	17	ad	ad	NOUN
fnp-5848	66	18	,	,	PUNCT
fnp-5848	66	19	such	such	ADJ
fnp-5848	66	20	as	as	ADP
fnp-5848	66	21	neurofibrillary	neurofibrillary	ADJ
fnp-5848	66	22	tangles	tangle	NOUN
fnp-5848	66	23	and	and	CCONJ
fnp-5848	66	24	amyloid	amyloid	NOUN
fnp-5848	66	25	plaques	plaque	NOUN
fnp-5848	66	26	,	,	PUNCT
fnp-5848	66	27	and	and	CCONJ
fnp-5848	66	28	ultimately	ultimately	ADV
fnp-5848	66	29	to	to	ADP
fnp-5848	66	30	cognitive	cognitive	ADJ
fnp-5848	66	31	decline	decline	NOUN
fnp-5848	66	32	,	,	PUNCT
fnp-5848	66	33	remains	remain	VERB
fnp-5848	66	34	unclear	unclear	ADJ
fnp-5848	66	35	—	—	PUNCT
fnp-5848	66	36	a	a	DET
fnp-5848	66	37	critical	critical	ADJ
fnp-5848	66	38	gap	gap	NOUN
fnp-5848	66	39	in	in	ADP
fnp-5848	66	40	our	our	PRON
fnp-5848	66	41	knowledge	knowledge	NOUN
fnp-5848	66	42	.	.	PUNCT
fnp-5848	67	1	a	a	DET
fnp-5848	67	2	study	study	NOUN
fnp-5848	67	3	by	by	ADP
fnp-5848	67	4	yang	yang	PROPN
fnp-5848	67	5	et	et	PROPN
fnp-5848	67	6	al	al	PROPN
fnp-5848	67	7	.	.	PROPN
fnp-5848	67	8	published	publish	VERB
fnp-5848	67	9	in	in	ADP
fnp-5848	67	10	nature	nature	NOUN
fnp-5848	67	11	communications	communication	NOUN
fnp-5848	67	12	investigates	investigate	VERB
fnp-5848	67	13	how	how	SCONJ
fnp-5848	67	14	cell	cell	NOUN
fnp-5848	67	15	-	-	PUNCT
fnp-5848	67	16	type	type	NOUN
fnp-5848	67	17	-	-	PUNCT
fnp-5848	67	18	specific	specific	ADJ
fnp-5848	67	19	polygenic	polygenic	ADJ
fnp-5848	67	20	risk	risk	NOUN
fnp-5848	67	21	scores	score	NOUN
fnp-5848	67	22	(	(	PUNCT
fnp-5848	67	23	adprs	adprs	ADJ
fnp-5848	67	24	)	)	PUNCT
fnp-5848	67	25	for	for	ADP
fnp-5848	67	26	ad	ad	NOUN
fnp-5848	67	27	are	be	AUX
fnp-5848	67	28	associated	associate	VERB
fnp-5848	67	29	with	with	ADP
fnp-5848	67	30	distinct	distinct	ADJ
fnp-5848	67	31	pathological	pathological	ADJ
fnp-5848	67	32	processes	process	NOUN
fnp-5848	67	33	(	(	PUNCT
fnp-5848	67	34	yang	yang	PROPN
fnp-5848	67	35	et	et	PROPN
fnp-5848	67	36	al	al	PROPN
fnp-5848	67	37	.	.	PROPN
fnp-5848	67	38	,	,	PUNCT
fnp-5848	67	39	2023	2023	NUM
fnp-5848	67	40	)	)	PUNCT
fnp-5848	67	41	.	.	PUNCT
fnp-5848	68	1	by	by	ADP
fnp-5848	68	2	deriving	derive	VERB
fnp-5848	68	3	adprs	adprs	ADV
fnp-5848	68	4	from	from	ADP
fnp-5848	68	5	large	large	ADJ
fnp-5848	68	6	-	-	PUNCT
fnp-5848	68	7	scale	scale	NOUN
fnp-5848	68	8	genomewide	genomewide	NOUN
fnp-5848	68	9	association	association	NOUN
fnp-5848	68	10	studies	study	NOUN
fnp-5848	68	11	(	(	PUNCT
fnp-5848	68	12	gwas	gwas	PROPN
fnp-5848	68	13	)	)	PUNCT
fnp-5848	68	14	and	and	CCONJ
fnp-5848	68	15	leveraging	leverage	VERB
fnp-5848	68	16	single	single	ADJ
fnp-5848	68	17	nucleus	nucleus	NOUN
fnp-5848	68	18	rna	rna	NOUN
fnp-5848	68	19	sequencing	sequence	VERB
fnp-5848	68	20	(	(	PUNCT
fnp-5848	68	21	snrna	snrna	ADJ
fnp-5848	68	22	-	-	PUNCT
fnp-5848	68	23	seq	seq	NOUN
fnp-5848	68	24	)	)	PUNCT
fnp-5848	68	25	data	datum	NOUN
fnp-5848	68	26	,	,	PUNCT
fnp-5848	68	27	the	the	DET
fnp-5848	68	28	researchers	researcher	NOUN
fnp-5848	68	29	assessed	assess	VERB
fnp-5848	68	30	the	the	DET
fnp-5848	68	31	impact	impact	NOUN
fnp-5848	68	32	of	of	ADP
fnp-5848	68	33	genetic	genetic	ADJ
fnp-5848	68	34	risk	risk	NOUN
fnp-5848	68	35	localized	localize	VERB
fnp-5848	68	36	to	to	ADP
fnp-5848	68	37	different	different	ADJ
fnp-5848	68	38	brain	brain	NOUN
fnp-5848	68	39	cell	cell	NOUN
fnp-5848	68	40	types	type	NOUN
fnp-5848	68	41	,	,	PUNCT
fnp-5848	68	42	focusing	focus	VERB
fnp-5848	68	43	on	on	ADP
fnp-5848	68	44	microglia	microglia	ADJ
fnp-5848	68	45	and	and	CCONJ
fnp-5848	68	46	astrocytes	astrocyte	NOUN
fnp-5848	68	47	,	,	PUNCT
fnp-5848	68	48	on	on	ADP
fnp-5848	68	49	various	various	ADJ
fnp-5848	68	50	ad	ad	NOUN
fnp-5848	68	51	endophenotypes	endophenotype	NOUN
fnp-5848	68	52	.	.	PUNCT
fnp-5848	69	1	using	use	VERB
fnp-5848	69	2	data	datum	NOUN
fnp-5848	69	3	from	from	ADP
fnp-5848	69	4	the	the	DET
fnp-5848	69	5	religious	religious	ADJ
fnp-5848	69	6	orders	order	NOUN
fnp-5848	69	7	study	study	VERB
fnp-5848	69	8	and	and	CCONJ
fnp-5848	69	9	the	the	DET
fnp-5848	69	10	rush	rush	NOUN
fnp-5848	69	11	memory	memory	NOUN
fnp-5848	69	12	and	and	CCONJ
fnp-5848	69	13	aging	age	VERB
fnp-5848	69	14	project	project	NOUN
fnp-5848	69	15	(	(	PUNCT
fnp-5848	69	16	rosmap	rosmap	NOUN
fnp-5848	69	17	)	)	PUNCT
fnp-5848	69	18	,	,	PUNCT
fnp-5848	69	19	as	as	ADV
fnp-5848	69	20	well	well	ADV
fnp-5848	69	21	as	as	ADP
fnp-5848	69	22	the	the	DET
fnp-5848	69	23	anti	anti	ADJ
fnp-5848	69	24	-	-	ADJ
fnp-5848	69	25	amyloid	amyloid	ADJ
fnp-5848	69	26	treatment	treatment	NOUN
fnp-5848	69	27	in	in	ADP
fnp-5848	69	28	asymptomatic	asymptomatic	PROPN
fnp-5848	69	29	alzheimer	alzheimer	PROPN
fnp-5848	69	30	’s	’s	PART
fnp-5848	69	31	(	(	PUNCT
fnp-5848	69	32	a4	a4	NOUN
fnp-5848	69	33	)	)	PUNCT
fnp-5848	69	34	study	study	NOUN
fnp-5848	69	35	,	,	PUNCT
fnp-5848	69	36	the	the	DET
fnp-5848	69	37	study	study	NOUN
fnp-5848	69	38	found	find	VERB
fnp-5848	69	39	that	that	SCONJ
fnp-5848	69	40	astrocytic	astrocytic	ADJ
fnp-5848	69	41	adprs	adprs	NOUN
fnp-5848	69	42	were	be	AUX
fnp-5848	69	43	primarily	primarily	ADV
fnp-5848	69	44	associated	associate	VERB
fnp-5848	69	45	with	with	ADP
fnp-5848	69	46	amyloid	amyloid	NOUN
fnp-5848	69	47	-	-	PUNCT
fnp-5848	69	48	β	β	X
fnp-5848	69	49	(	(	PUNCT
fnp-5848	69	50	aβ	aβ	PROPN
fnp-5848	69	51	)	)	PUNCT
fnp-5848	69	52	pathology	pathology	NOUN
fnp-5848	69	53	,	,	PUNCT
fnp-5848	69	54	while	while	SCONJ
fnp-5848	69	55	microglial	microglial	ADJ
fnp-5848	69	56	adprs	adprs	NOUN
fnp-5848	69	57	were	be	AUX
fnp-5848	69	58	linked	link	VERB
fnp-5848	69	59	to	to	ADP
fnp-5848	69	60	both	both	PRON
fnp-5848	69	61	aβ	aβ	PROPN
fnp-5848	69	62	and	and	CCONJ
fnp-5848	69	63	tau	tau	PROPN
fnp-5848	69	64	pathologies	pathology	NOUN
fnp-5848	69	65	,	,	PUNCT
fnp-5848	69	66	as	as	ADV
fnp-5848	69	67	well	well	ADV
fnp-5848	69	68	as	as	ADP
fnp-5848	69	69	cognitive	cognitive	ADJ
fnp-5848	69	70	decline	decline	NOUN
fnp-5848	69	71	.	.	PUNCT
fnp-5848	70	1	the	the	DET
fnp-5848	70	2	findings	finding	NOUN
fnp-5848	70	3	suggest	suggest	VERB
fnp-5848	70	4	that	that	SCONJ
fnp-5848	70	5	genetic	genetic	ADJ
fnp-5848	70	6	risks	risk	NOUN
fnp-5848	70	7	associated	associate	VERB
fnp-5848	70	8	with	with	ADP
fnp-5848	70	9	astrocytes	astrocyte	NOUN
fnp-5848	70	10	contribute	contribute	VERB
fnp-5848	70	11	to	to	ADP
fnp-5848	70	12	early	early	ADJ
fnp-5848	70	13	aβ	aβ	NOUN
fnp-5848	70	14	accumulation	accumulation	NOUN
fnp-5848	70	15	,	,	PUNCT
fnp-5848	70	16	whereas	whereas	SCONJ
fnp-5848	70	17	microglial	microglial	ADJ
fnp-5848	70	18	genetic	genetic	ADJ
fnp-5848	70	19	risks	risk	NOUN
fnp-5848	70	20	drive	drive	VERB
fnp-5848	70	21	later	later	ADJ
fnp-5848	70	22	-	-	PUNCT
fnp-5848	70	23	stage	stage	NOUN
fnp-5848	70	24	pathological	pathological	ADJ
fnp-5848	70	25	changes	change	NOUN
fnp-5848	70	26	and	and	CCONJ
fnp-5848	70	27	cognitive	cognitive	ADJ
fnp-5848	70	28	impairment	impairment	NOUN
fnp-5848	70	29	.	.	PUNCT
fnp-5848	71	1	yang	yang	PROPN
fnp-5848	71	2	et	et	PROPN
fnp-5848	71	3	al	al	PROPN
fnp-5848	71	4	.	.	PROPN
fnp-5848	71	5	utilized	utilize	VERB
fnp-5848	71	6	causal	causal	PROPN
fnp-5848	71	7	modeling	modeling	NOUN
fnp-5848	71	8	to	to	PART
fnp-5848	71	9	map	map	VERB
fnp-5848	71	10	the	the	DET
fnp-5848	71	11	contributions	contribution	NOUN
fnp-5848	71	12	of	of	ADP
fnp-5848	71	13	cell	cell	NOUN
fnp-5848	71	14	-	-	PUNCT
fnp-5848	71	15	type	type	NOUN
fnp-5848	71	16	-	-	PUNCT
fnp-5848	71	17	specific	specific	ADJ
fnp-5848	71	18	adprs	adprs	NOUN
fnp-5848	71	19	to	to	ADP
fnp-5848	71	20	the	the	DET
fnp-5848	71	21	sequence	sequence	NOUN
fnp-5848	71	22	of	of	ADP
fnp-5848	71	23	ad	ad	NOUN
fnp-5848	71	24	pathophysiology	pathophysiology	NOUN
fnp-5848	71	25	.	.	PUNCT
fnp-5848	72	1	the	the	DET
fnp-5848	72	2	study	study	NOUN
fnp-5848	72	3	suggests	suggest	VERB
fnp-5848	72	4	that	that	SCONJ
fnp-5848	72	5	astrocytic	astrocytic	ADJ
fnp-5848	72	6	genetic	genetic	ADJ
fnp-5848	72	7	risks	risk	NOUN
fnp-5848	72	8	affect	affect	VERB
fnp-5848	72	9	ad	ad	NOUN
fnp-5848	72	10	primarily	primarily	ADV
fnp-5848	72	11	through	through	ADP
fnp-5848	72	12	aβ	aβ	PRON
fnp-5848	72	13	accumulation	accumulation	NOUN
fnp-5848	72	14	in	in	ADP
fnp-5848	72	15	diffuse	diffuse	NOUN
fnp-5848	72	16	and	and	CCONJ
fnp-5848	72	17	neuritic	neuritic	ADJ
fnp-5848	72	18	plaques	plaque	NOUN
fnp-5848	72	19	,	,	PUNCT
fnp-5848	72	20	whereas	whereas	SCONJ
fnp-5848	72	21	microglial	microglial	ADJ
fnp-5848	72	22	genetic	genetic	ADJ
fnp-5848	72	23	risks	risk	NOUN
fnp-5848	72	24	have	have	VERB
fnp-5848	72	25	broader	broad	ADJ
fnp-5848	72	26	effects	effect	NOUN
fnp-5848	72	27	on	on	ADP
fnp-5848	72	28	neuritic	neuritic	ADJ
fnp-5848	72	29	plaques	plaque	NOUN
fnp-5848	72	30	,	,	PUNCT
fnp-5848	72	31	tau	tau	PROPN
fnp-5848	72	32	neurofibrillary	neurofibrillary	ADJ
fnp-5848	72	33	tangles	tangle	NOUN
fnp-5848	72	34	,	,	PUNCT
fnp-5848	72	35	and	and	CCONJ
fnp-5848	72	36	cognitive	cognitive	ADJ
fnp-5848	72	37	decline	decline	NOUN
fnp-5848	72	38	.	.	PUNCT
fnp-5848	73	1	this	this	PRON
fnp-5848	73	2	was	be	AUX
fnp-5848	73	3	supported	support	VERB
fnp-5848	73	4	by	by	ADP
fnp-5848	73	5	data	datum	NOUN
fnp-5848	73	6	from	from	ADP
fnp-5848	73	7	the	the	DET
fnp-5848	73	8	a4	a4	NOUN
fnp-5848	73	9	study	study	NOUN
fnp-5848	73	10	,	,	PUNCT
fnp-5848	73	11	which	which	PRON
fnp-5848	73	12	showed	show	VERB
fnp-5848	73	13	that	that	SCONJ
fnp-5848	73	14	microglial	microglial	ADJ
fnp-5848	73	15	adprs	adprs	NOUN
fnp-5848	73	16	were	be	AUX
fnp-5848	73	17	significantly	significantly	ADV
fnp-5848	73	18	associated	associate	VERB
fnp-5848	73	19	with	with	ADP
fnp-5848	73	20	in	in	ADP
fnp-5848	73	21	vivo	vivo	NOUN
fnp-5848	73	22	tau	tau	PROPN
fnp-5848	73	23	pet	pet	NOUN
fnp-5848	73	24	measures	measure	NOUN
fnp-5848	73	25	,	,	PUNCT
fnp-5848	73	26	indicating	indicate	VERB
fnp-5848	73	27	an	an	DET
fnp-5848	73	28	early	early	ADJ
fnp-5848	73	29	role	role	NOUN
fnp-5848	73	30	in	in	ADP
fnp-5848	73	31	tau	tau	PROPN
fnp-5848	73	32	pathology	pathology	NOUN
fnp-5848	73	33	.	.	PUNCT
fnp-5848	74	1	the	the	DET
fnp-5848	74	2	research	research	NOUN
fnp-5848	74	3	underscores	underscore	VERB
fnp-5848	74	4	the	the	DET
fnp-5848	74	5	importance	importance	NOUN
fnp-5848	74	6	of	of	ADP
fnp-5848	74	7	considering	consider	VERB
fnp-5848	74	8	cell	cell	NOUN
fnp-5848	74	9	-	-	PUNCT
fnp-5848	74	10	type	type	NOUN
fnp-5848	74	11	-	-	PUNCT
fnp-5848	74	12	specific	specific	ADJ
fnp-5848	74	13	genetic	genetic	ADJ
fnp-5848	74	14	risks	risk	NOUN
fnp-5848	74	15	in	in	ADP
fnp-5848	74	16	understanding	understand	VERB
fnp-5848	74	17	the	the	DET
fnp-5848	74	18	progression	progression	NOUN
fnp-5848	74	19	of	of	ADP
fnp-5848	74	20	ad	ad	NOUN
fnp-5848	74	21	and	and	CCONJ
fnp-5848	74	22	highlights	highlight	NOUN
fnp-5848	74	23	potential	potential	ADJ
fnp-5848	74	24	targets	target	NOUN
fnp-5848	74	25	for	for	ADP
fnp-5848	74	26	therapeutic	therapeutic	ADJ
fnp-5848	74	27	interventions	intervention	NOUN
fnp-5848	74	28	.	.	PUNCT
fnp-5848	75	1	these	these	DET
fnp-5848	75	2	insights	insight	NOUN
fnp-5848	75	3	pave	pave	VERB
fnp-5848	75	4	the	the	DET
fnp-5848	75	5	way	way	NOUN
fnp-5848	75	6	for	for	SCONJ
fnp-5848	75	7	future	future	ADJ
fnp-5848	75	8	studies	study	NOUN
fnp-5848	75	9	to	to	PART
fnp-5848	75	10	explore	explore	VERB
fnp-5848	75	11	genetically	genetically	ADV
fnp-5848	75	12	guided	guide	VERB
fnp-5848	75	13	approaches	approach	NOUN
fnp-5848	75	14	to	to	ADP
fnp-5848	75	15	ad	ad	NOUN
fnp-5848	75	16	treatment	treatment	NOUN
fnp-5848	75	17	,	,	PUNCT
fnp-5848	75	18	focusing	focus	VERB
fnp-5848	75	19	on	on	ADP
fnp-5848	75	20	modulating	modulate	VERB
fnp-5848	75	21	specific	specific	ADJ
fnp-5848	75	22	glial	glial	ADJ
fnp-5848	75	23	cell	cell	NOUN
fnp-5848	75	24	functions	function	NOUN
fnp-5848	75	25	to	to	PART
fnp-5848	75	26	mitigate	mitigate	VERB
fnp-5848	75	27	disease	disease	NOUN
fnp-5848	75	28	progression	progression	NOUN
fnp-5848	75	29	.	.	PUNCT
fnp-5848	76	1	5	5	X
fnp-5848	76	2	.	.	X
fnp-5848	76	3	 	 	SPACE
fnp-5848	76	4	histological	histological	ADJ
fnp-5848	76	5	brain	brain	NOUN
fnp-5848	76	6	age	age	NOUN
fnp-5848	76	7	acceleration	acceleration	NOUN
fnp-5848	76	8	using	use	VERB
fnp-5848	76	9	digital	digital	ADJ
fnp-5848	76	10	neuropathology	neuropathology	NOUN
fnp-5848	76	11	and	and	CCONJ
fnp-5848	76	12	artificial	artificial	ADJ
fnp-5848	76	13	intelligence	intelligence	NOUN
fnp-5848	76	14	understanding	understanding	NOUN
fnp-5848	76	15	mechanisms	mechanism	NOUN
fnp-5848	76	16	of	of	ADP
fnp-5848	76	17	human	human	ADJ
fnp-5848	76	18	brain	brain	NOUN
fnp-5848	76	19	aging	aging	NOUN
fnp-5848	76	20	is	be	AUX
fnp-5848	76	21	increasingly	increasingly	ADV
fnp-5848	76	22	important	important	ADJ
fnp-5848	76	23	as	as	SCONJ
fnp-5848	76	24	the	the	DET
fnp-5848	76	25	elderly	elderly	ADJ
fnp-5848	76	26	population	population	NOUN
fnp-5848	76	27	grows	grow	VERB
fnp-5848	76	28	,	,	PUNCT
fnp-5848	76	29	given	give	VERB
fnp-5848	76	30	the	the	DET
fnp-5848	76	31	complexity	complexity	NOUN
fnp-5848	76	32	of	of	ADP
fnp-5848	76	33	structural	structural	ADJ
fnp-5848	76	34	changes	change	NOUN
fnp-5848	76	35	that	that	PRON
fnp-5848	76	36	arise	arise	VERB
fnp-5848	76	37	from	from	ADP
fnp-5848	76	38	a	a	DET
fnp-5848	76	39	spectrum	spectrum	NOUN
fnp-5848	76	40	of	of	ADP
fnp-5848	76	41	normal	normal	ADJ
fnp-5848	76	42	and	and	CCONJ
fnp-5848	76	43	pathological	pathological	ADJ
fnp-5848	76	44	processes	process	NOUN
fnp-5848	76	45	affecting	affect	VERB
fnp-5848	76	46	functional	functional	ADJ
fnp-5848	76	47	impairment	impairment	NOUN
fnp-5848	76	48	.	.	PUNCT
fnp-5848	77	1	one	one	NUM
fnp-5848	77	2	highly	highly	ADV
fnp-5848	77	3	effective	effective	ADJ
fnp-5848	77	4	approach	approach	NOUN
fnp-5848	77	5	to	to	ADP
fnp-5848	77	6	studying	study	VERB
fnp-5848	77	7	aging	aging	NOUN
fnp-5848	77	8	is	be	AUX
fnp-5848	77	9	through	through	ADP
fnp-5848	77	10	biological	biological	ADJ
fnp-5848	77	11	clocks	clock	NOUN
fnp-5848	77	12	,	,	PUNCT
fnp-5848	77	13	initially	initially	ADV
fnp-5848	77	14	developed	develop	VERB
fnp-5848	77	15	using	use	VERB
fnp-5848	77	16	dna	dna	PROPN
fnp-5848	77	17	methylation	methylation	NOUN
fnp-5848	77	18	analysis	analysis	NOUN
fnp-5848	77	19	.	.	PUNCT
fnp-5848	78	1	dna	dna	PROPN
fnp-5848	78	2	methylation	methylation	NOUN
fnp-5848	78	3	clocks	clock	NOUN
fnp-5848	78	4	estimate	estimate	VERB
fnp-5848	78	5	biological	biological	ADJ
fnp-5848	78	6	age	age	NOUN
fnp-5848	78	7	by	by	ADP
fnp-5848	78	8	measuring	measure	VERB
fnp-5848	78	9	methylation	methylation	NOUN
fnp-5848	78	10	patterns	pattern	NOUN
fnp-5848	78	11	at	at	ADP
fnp-5848	78	12	specific	specific	ADJ
fnp-5848	78	13	cpg	cpg	NOUN
fnp-5848	78	14	sites	site	NOUN
fnp-5848	78	15	in	in	ADP
fnp-5848	78	16	the	the	DET
fnp-5848	78	17	genome	genome	NOUN
fnp-5848	78	18	,	,	PUNCT
fnp-5848	78	19	reflecting	reflect	VERB
fnp-5848	78	20	cellular	cellular	ADJ
fnp-5848	78	21	aging	age	VERB
fnp-5848	78	22	processes	process	NOUN
fnp-5848	78	23	.	.	PUNCT
fnp-5848	79	1	this	this	DET
fnp-5848	79	2	method	method	NOUN
fnp-5848	79	3	can	can	AUX
fnp-5848	79	4	be	be	AUX
fnp-5848	79	5	used	use	VERB
fnp-5848	79	6	to	to	PART
fnp-5848	79	7	reveal	reveal	VERB
fnp-5848	79	8	discrepancies	discrepancy	NOUN
fnp-5848	79	9	between	between	ADP
fnp-5848	79	10	biological	biological	ADJ
fnp-5848	79	11	and	and	CCONJ
fnp-5848	79	12	chronological	chronological	ADJ
fnp-5848	79	13	age	age	NOUN
fnp-5848	79	14	,	,	PUNCT
fnp-5848	79	15	providing	provide	VERB
fnp-5848	79	16	insights	insight	NOUN
fnp-5848	79	17	into	into	ADP
fnp-5848	79	18	age	age	NOUN
fnp-5848	79	19	acceleration	acceleration	NOUN
fnp-5848	79	20	or	or	CCONJ
fnp-5848	79	21	deceleration	deceleration	NOUN
fnp-5848	79	22	that	that	PRON
fnp-5848	79	23	can	can	AUX
fnp-5848	79	24	be	be	AUX
fnp-5848	79	25	linked	link	VERB
fnp-5848	79	26	to	to	ADP
fnp-5848	79	27	environmental	environmental	ADJ
fnp-5848	79	28	and	and	CCONJ
fnp-5848	79	29	genetic	genetic	ADJ
fnp-5848	79	30	factors	factor	NOUN
fnp-5848	79	31	.	.	PUNCT
fnp-5848	80	1	in	in	ADP
fnp-5848	80	2	a	a	DET
fnp-5848	80	3	study	study	NOUN
fnp-5848	80	4	by	by	ADP
fnp-5848	80	5	marx	marx	PROPN
fnp-5848	80	6	et	et	PROPN
fnp-5848	80	7	al	al	PROPN
fnp-5848	80	8	.	.	PROPN
fnp-5848	80	9	published	publish	VERB
fnp-5848	80	10	in	in	ADP
fnp-5848	80	11	acta	acta	PROPN
fnp-5848	80	12	neuropathologica	neuropathologica	PROPN
fnp-5848	80	13	,	,	PUNCT
fnp-5848	80	14	and	and	CCONJ
fnp-5848	80	15	led	lead	VERB
fnp-5848	80	16	by	by	ADP
fnp-5848	80	17	the	the	DET
fnp-5848	80	18	author	author	NOUN
fnp-5848	80	19	of	of	ADP
fnp-5848	80	20	this	this	DET
fnp-5848	80	21	review	review	NOUN
fnp-5848	80	22	,	,	PUNCT
fnp-5848	80	23	the	the	DET
fnp-5848	80	24	authors	author	NOUN
fnp-5848	80	25	leverage	leverage	VERB
fnp-5848	80	26	digital	digital	ADJ
fnp-5848	80	27	pathology	pathology	NOUN
fnp-5848	80	28	to	to	PART
fnp-5848	80	29	deploy	deploy	VERB
fnp-5848	80	30	multiple	multiple	ADJ
fnp-5848	80	31	instance	instance	NOUN
fnp-5848	80	32	learning	learning	NOUN
fnp-5848	80	33	(	(	PUNCT
fnp-5848	80	34	mil	mil	NOUN
fnp-5848	80	35	)	)	PUNCT
fnp-5848	80	36	to	to	PART
fnp-5848	80	37	estimate	estimate	VERB
fnp-5848	80	38	brain	brain	NOUN
fnp-5848	80	39	age	age	NOUN
fnp-5848	80	40	from	from	ADP
fnp-5848	80	41	histopathological	histopathological	ADJ
fnp-5848	80	42	whole	whole	ADJ
fnp-5848	80	43	slide	slide	NOUN
fnp-5848	80	44	images	image	NOUN
fnp-5848	80	45	(	(	PUNCT
fnp-5848	80	46	marx	marx	PROPN
fnp-5848	80	47	et	et	PROPN
fnp-5848	80	48	al	al	PROPN
fnp-5848	80	49	.	.	PROPN
fnp-5848	80	50	,	,	PUNCT
fnp-5848	80	51	2023	2023	NUM
fnp-5848	80	52	)	)	PUNCT
fnp-5848	80	53	.	.	PUNCT
fnp-5848	81	1	employing	employ	VERB
fnp-5848	81	2	an	an	DET
fnp-5848	81	3	attention	attention	NOUN
fnp-5848	81	4	-	-	PUNCT
fnp-5848	81	5	based	base	VERB
fnp-5848	81	6	deep	deep	ADJ
fnp-5848	81	7	mil	mil	PROPN
fnp-5848	81	8	model	model	NOUN
fnp-5848	81	9	,	,	PUNCT
fnp-5848	81	10	the	the	DET
fnp-5848	81	11	team	team	NOUN
fnp-5848	81	12	analyzed	analyze	VERB
fnp-5848	81	13	digitized	digitize	VERB
fnp-5848	81	14	postmortem	postmortem	NOUN
fnp-5848	81	15	hippocampal	hippocampal	ADJ
fnp-5848	81	16	sections	section	NOUN
fnp-5848	81	17	to	to	PART
fnp-5848	81	18	develop	develop	VERB
fnp-5848	81	19	an	an	DET
fnp-5848	81	20	advanced	advanced	ADJ
fnp-5848	81	21	brain	brain	NOUN
fnp-5848	81	22	age	age	NOUN
fnp-5848	81	23	estimation	estimation	NOUN
fnp-5848	81	24	tool	tool	NOUN
fnp-5848	81	25	,	,	PUNCT
fnp-5848	81	26	achieving	achieve	VERB
fnp-5848	81	27	a	a	DET
fnp-5848	81	28	mean	mean	ADJ
fnp-5848	81	29	absolute	absolute	ADJ
fnp-5848	81	30	error	error	NOUN
fnp-5848	81	31	of	of	ADP
fnp-5848	81	32	5.45	5.45	NUM
fnp-5848	81	33	years	year	NOUN
fnp-5848	81	34	(	(	PUNCT
fnp-5848	81	35	figure	figure	NOUN
fnp-5848	81	36	 	 	SPACE
fnp-5848	81	37	4	4	NUM
fnp-5848	81	38	)	)	PUNCT
fnp-5848	81	39	.	.	PUNCT
fnp-5848	82	1	the	the	DET
fnp-5848	82	2	integration	integration	NOUN
fnp-5848	82	3	of	of	ADP
fnp-5848	82	4	spatially	spatially	ADV
fnp-5848	82	5	resolved	resolve	VERB
fnp-5848	82	6	graph	graph	NOUN
fnp-5848	82	7	convolutional	convolutional	ADJ
fnp-5848	82	8	networks	network	NOUN
fnp-5848	82	9	(	(	PUNCT
fnp-5848	82	10	gcns	gcns	PROPN
fnp-5848	82	11	)	)	PUNCT
fnp-5848	82	12	allowed	allow	VERB
fnp-5848	82	13	the	the	DET
fnp-5848	82	14	model	model	NOUN
fnp-5848	82	15	to	to	PART
fnp-5848	82	16	consider	consider	VERB
fnp-5848	82	17	neuro	neuro	PROPN
fnp-5848	82	18	https://doi.org/10.17879/freeneuropathology-2024free	https://doi.org/10.17879/freeneuropathology-2024free	PROPN
fnp-5848	82	19	neuropathology	neuropathology	PROPN
fnp-5848	82	20	5:31	5:31	NUM
fnp-5848	82	21	(	(	PUNCT
fnp-5848	82	22	2024	2024	NUM
fnp-5848	82	23	)	)	PUNCT
fnp-5848	83	1	john	john	PROPN
fnp-5848	83	2	f.	f.	PROPN
fnp-5848	83	3	crary	crary	PROPN
fnp-5848	83	4	doi	doi	PROPN
fnp-5848	83	5	:	:	PUNCT
fnp-5848	83	6	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	83	7	page	page	NOUN
fnp-5848	83	8	6	6	NUM
fnp-5848	83	9	of	of	ADP
fnp-5848	83	10	12	12	NUM
fnp-5848	83	11	figure	figure	NOUN
fnp-5848	83	12	 	 	SPACE
fnp-5848	83	13	3	3	NUM
fnp-5848	83	14	.	.	PUNCT
fnp-5848	83	15	association	association	NOUN
fnp-5848	83	16	of	of	ADP
fnp-5848	83	17	cell	cell	NOUN
fnp-5848	83	18	-	-	PUNCT
fnp-5848	83	19	type	type	NOUN
fnp-5848	83	20	-	-	PUNCT
fnp-5848	83	21	specific	specific	ADJ
fnp-5848	83	22	ad	ad	NOUN
fnp-5848	83	23	polygenic	polygenic	ADJ
fnp-5848	83	24	risk	risk	NOUN
fnp-5848	83	25	scores	score	NOUN
fnp-5848	83	26	.	.	PUNCT
fnp-5848	84	1	rosmap	rosmap	NOUN
fnp-5848	84	2	,	,	PUNCT
fnp-5848	84	3	religious	religious	ADJ
fnp-5848	84	4	orders	order	NOUN
fnp-5848	84	5	study	study	NOUN
fnp-5848	84	6	/	/	SYM
fnp-5848	84	7	memory	memory	NOUN
fnp-5848	84	8	and	and	CCONJ
fnp-5848	84	9	aging	age	VERB
fnp-5848	84	10	project	project	NOUN
fnp-5848	84	11	;	;	PUNCT
fnp-5848	84	12	ad	ad	NOUN
fnp-5848	84	13	,	,	PUNCT
fnp-5848	84	14	alzheimer	alzheimer	NOUN
fnp-5848	84	15	disease	disease	NOUN
fnp-5848	84	16	;	;	PUNCT
fnp-5848	84	17	prs	prs	NOUN
fnp-5848	84	18	,	,	PUNCT
fnp-5848	84	19	polygenic	polygenic	ADJ
fnp-5848	84	20	risk	risk	NOUN
fnp-5848	84	21	score	score	NOUN
fnp-5848	84	22	;	;	PUNCT
fnp-5848	84	23	ex	ex	X
fnp-5848	84	24	,	,	PUNCT
fnp-5848	84	25	exitatory	exitatory	ADJ
fnp-5848	84	26	neurons	neuron	NOUN
fnp-5848	84	27	;	;	PUNCT
fnp-5848	84	28	in	in	ADP
fnp-5848	84	29	,	,	PUNCT
fnp-5848	84	30	inhibatory	inhibatory	NOUN
fnp-5848	84	31	neurons	neuron	NOUN
fnp-5848	84	32	;	;	PUNCT
fnp-5848	84	33	ast	ast	X
fnp-5848	84	34	,	,	PUNCT
fnp-5848	84	35	astrocytes	astrocyte	NOUN
fnp-5848	84	36	;	;	PUNCT
fnp-5848	84	37	mic	mic	ADJ
fnp-5848	84	38	,	,	PUNCT
fnp-5848	84	39	microglia	microglia	ADJ
fnp-5848	84	40	;	;	PUNCT
fnp-5848	84	41	oli	oli	ADJ
fnp-5848	84	42	,	,	PUNCT
fnp-5848	84	43	oligodendrocytes	oligodendrocyte	NOUN
fnp-5848	84	44	;	;	PUNCT
fnp-5848	84	45	opc	opc	PROPN
fnp-5848	84	46	,	,	PUNCT
fnp-5848	84	47	oligodendrocyte	oligodendrocyte	ADJ
fnp-5848	84	48	precursors	precursor	NOUN
fnp-5848	84	49	.	.	PUNCT
fnp-5848	84	50	reproduced	reproduce	VERB
fnp-5848	84	51	in	in	ADP
fnp-5848	84	52	under	under	ADP
fnp-5848	84	53	a	a	DET
fnp-5848	84	54	creative	creative	ADJ
fnp-5848	84	55	commons	common	NOUN
fnp-5848	84	56	attribution	attribution	NOUN
fnp-5848	84	57	4.0	4.0	NUM
fnp-5848	84	58	international	international	ADJ
fnp-5848	84	59	license	license	NOUN
fnp-5848	84	60	(	(	PUNCT
fnp-5848	84	61	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	84	62	)	)	PUNCT
fnp-5848	84	63	anatomical	anatomical	ADJ
fnp-5848	84	64	context	context	NOUN
fnp-5848	84	65	,	,	PUNCT
fnp-5848	84	66	resulting	result	VERB
fnp-5848	84	67	in	in	ADP
fnp-5848	84	68	a	a	DET
fnp-5848	84	69	significant	significant	ADJ
fnp-5848	84	70	improvement	improvement	NOUN
fnp-5848	84	71	over	over	ADP
fnp-5848	84	72	traditional	traditional	ADJ
fnp-5848	84	73	methods	method	NOUN
fnp-5848	84	74	.	.	PUNCT
fnp-5848	85	1	marx	marx	PROPN
fnp-5848	85	2	et	et	PROPN
fnp-5848	85	3	al	al	PROPN
fnp-5848	85	4	.	.	PROPN
fnp-5848	85	5	identified	identify	VERB
fnp-5848	85	6	robust	robust	ADJ
fnp-5848	85	7	associations	association	NOUN
fnp-5848	85	8	between	between	ADP
fnp-5848	85	9	histopathologic	histopathologic	ADJ
fnp-5848	85	10	brain	brain	NOUN
fnp-5848	85	11	age	age	NOUN
fnp-5848	85	12	acceleration	acceleration	NOUN
fnp-5848	85	13	and	and	CCONJ
fnp-5848	85	14	clinical	clinical	ADJ
fnp-5848	85	15	and	and	CCONJ
fnp-5848	85	16	pathological	pathological	ADJ
fnp-5848	85	17	outcomes	outcome	NOUN
fnp-5848	85	18	,	,	PUNCT
fnp-5848	85	19	which	which	PRON
fnp-5848	85	20	were	be	AUX
fnp-5848	85	21	not	not	PART
fnp-5848	85	22	evident	evident	ADJ
fnp-5848	85	23	with	with	ADP
fnp-5848	85	24	gold	gold	ADJ
fnp-5848	85	25	standard	standard	ADJ
fnp-5848	85	26	epigenetic	epigenetic	ADJ
fnp-5848	85	27	measures	measure	NOUN
fnp-5848	85	28	.	.	PUNCT
fnp-5848	86	1	attention	attention	NOUN
fnp-5848	86	2	heatmaps	heatmap	NOUN
fnp-5848	86	3	generated	generate	VERB
fnp-5848	86	4	by	by	ADP
fnp-5848	86	5	the	the	DET
fnp-5848	86	6	model	model	NOUN
fnp-5848	86	7	highlighted	highlight	VERB
fnp-5848	86	8	aging	age	VERB
fnp-5848	86	9	-	-	PUNCT
fnp-5848	86	10	vulnerable	vulnerable	ADJ
fnp-5848	86	11	brain	brain	NOUN
fnp-5848	86	12	regions	region	NOUN
fnp-5848	86	13	,	,	PUNCT
fnp-5848	86	14	such	such	ADJ
fnp-5848	86	15	as	as	ADP
fnp-5848	86	16	specific	specific	ADJ
fnp-5848	86	17	white	white	ADJ
fnp-5848	86	18	matter	matter	NOUN
fnp-5848	86	19	areas	area	NOUN
fnp-5848	86	20	and	and	CCONJ
fnp-5848	86	21	hippocampal	hippocampal	ADJ
fnp-5848	86	22	subfields	subfield	NOUN
fnp-5848	86	23	,	,	PUNCT
fnp-5848	86	24	as	as	ADV
fnp-5848	86	25	critical	critical	ADJ
fnp-5848	86	26	for	for	ADP
fnp-5848	86	27	accurate	accurate	ADJ
fnp-5848	86	28	age	age	NOUN
fnp-5848	86	29	estimation	estimation	NOUN
fnp-5848	86	30	.	.	PUNCT
fnp-5848	87	1	this	this	DET
fnp-5848	87	2	study	study	NOUN
fnp-5848	87	3	emphasizes	emphasize	VERB
fnp-5848	87	4	the	the	DET
fnp-5848	87	5	potential	potential	NOUN
fnp-5848	87	6	of	of	ADP
fnp-5848	87	7	histopathological	histopathological	ADJ
fnp-5848	87	8	markers	marker	NOUN
fnp-5848	87	9	to	to	PART
fnp-5848	87	10	provide	provide	VERB
fnp-5848	87	11	deeper	deep	ADJ
fnp-5848	87	12	insights	insight	NOUN
fnp-5848	87	13	into	into	ADP
fnp-5848	87	14	brain	brain	NOUN
fnp-5848	87	15	aging	age	VERB
fnp-5848	87	16	mechanisms	mechanism	NOUN
fnp-5848	87	17	.	.	PUNCT
fnp-5848	88	1	additionally	additionally	ADV
fnp-5848	88	2	,	,	PUNCT
fnp-5848	88	3	the	the	DET
fnp-5848	88	4	combination	combination	NOUN
fnp-5848	88	5	of	of	ADP
fnp-5848	88	6	mil	mil	NOUN
fnp-5848	88	7	with	with	ADP
fnp-5848	88	8	gcns	gcns	PROPN
fnp-5848	88	9	presents	present	VERB
fnp-5848	88	10	a	a	DET
fnp-5848	88	11	novel	novel	ADJ
fnp-5848	88	12	methodology	methodology	NOUN
fnp-5848	88	13	for	for	ADP
fnp-5848	88	14	predicting	predict	VERB
fnp-5848	88	15	brain	brain	NOUN
fnp-5848	88	16	age	age	NOUN
fnp-5848	88	17	,	,	PUNCT
fnp-5848	88	18	offering	offer	VERB
fnp-5848	88	19	promising	promising	ADJ
fnp-5848	88	20	implications	implication	NOUN
fnp-5848	88	21	for	for	ADP
fnp-5848	88	22	understanding	understanding	NOUN
fnp-5848	88	23	and	and	CCONJ
fnp-5848	88	24	diagnosing	diagnose	VERB
fnp-5848	88	25	neurodegenerative	neurodegenerative	ADJ
fnp-5848	88	26	diseases	disease	NOUN
fnp-5848	88	27	and	and	CCONJ
fnp-5848	88	28	their	their	PRON
fnp-5848	88	29	progression	progression	NOUN
fnp-5848	88	30	.	.	PUNCT
fnp-5848	89	1	this	this	DET
fnp-5848	89	2	innovative	innovative	ADJ
fnp-5848	89	3	approach	approach	NOUN
fnp-5848	89	4	paves	pave	VERB
fnp-5848	89	5	the	the	DET
fnp-5848	89	6	way	way	NOUN
fnp-5848	89	7	for	for	ADP
fnp-5848	89	8	more	more	ADV
fnp-5848	89	9	precise	precise	ADJ
fnp-5848	89	10	and	and	CCONJ
fnp-5848	89	11	informative	informative	ADJ
fnp-5848	89	12	assessments	assessment	NOUN
fnp-5848	89	13	of	of	ADP
fnp-5848	89	14	age	age	NOUN
fnp-5848	89	15	-	-	PUNCT
fnp-5848	89	16	related	relate	VERB
fnp-5848	89	17	neuropathological	neuropathological	ADJ
fnp-5848	89	18	changes	change	NOUN
fnp-5848	89	19	.	.	PUNCT
fnp-5848	90	1	in	in	ADP
fnp-5848	90	2	this	this	DET
fnp-5848	90	3	context	context	NOUN
fnp-5848	90	4	,	,	PUNCT
fnp-5848	90	5	histoage	histoage	NOUN
fnp-5848	90	6	represents	represent	VERB
fnp-5848	90	7	a	a	DET
fnp-5848	90	8	cutting	cut	VERB
fnp-5848	90	9	-	-	PUNCT
fnp-5848	90	10	edge	edge	NOUN
fnp-5848	90	11	advancement	advancement	NOUN
fnp-5848	90	12	—	—	PUNCT
fnp-5848	90	13	an	an	DET
fnp-5848	90	14	ai	ai	NOUN
fnp-5848	90	15	-	-	PUNCT
fnp-5848	90	16	driven	drive	VERB
fnp-5848	90	17	digital	digital	ADJ
fnp-5848	90	18	neuropathology	neuropathology	NOUN
fnp-5848	90	19	tool	tool	NOUN
fnp-5848	90	20	designed	design	VERB
fnp-5848	90	21	to	to	PART
fnp-5848	90	22	study	study	VERB
fnp-5848	90	23	brain	brain	NOUN
fnp-5848	90	24	aging	aging	NOUN
fnp-5848	90	25	more	more	ADV
fnp-5848	90	26	precisely	precisely	ADV
fnp-5848	90	27	,	,	PUNCT
fnp-5848	90	28	leveraging	leverage	VERB
fnp-5848	90	29	advanced	advanced	ADJ
fnp-5848	90	30	computational	computational	ADJ
fnp-5848	90	31	techniques	technique	NOUN
fnp-5848	90	32	to	to	PART
fnp-5848	90	33	enhance	enhance	VERB
fnp-5848	90	34	our	our	PRON
fnp-5848	90	35	understanding	understanding	NOUN
fnp-5848	90	36	of	of	ADP
fnp-5848	90	37	age	age	NOUN
fnp-5848	90	38	-	-	PUNCT
fnp-5848	90	39	related	relate	VERB
fnp-5848	90	40	changes	change	NOUN
fnp-5848	90	41	in	in	ADP
fnp-5848	90	42	the	the	DET
fnp-5848	90	43	brain	brain	NOUN
fnp-5848	90	44	.	.	PUNCT
fnp-5848	91	1	6	6	NUM
fnp-5848	91	2	.	.	PUNCT
fnp-5848	91	3	 	 	SPACE
fnp-5848	91	4	decline	decline	NOUN
fnp-5848	91	5	in	in	ADP
fnp-5848	91	6	cerebrovascular	cerebrovascular	ADJ
fnp-5848	91	7	pathologies	pathology	NOUN
fnp-5848	91	8	over	over	ADP
fnp-5848	91	9	25	25	NUM
fnp-5848	91	10	years	year	NOUN
fnp-5848	91	11	recently	recently	ADV
fnp-5848	91	12	,	,	PUNCT
fnp-5848	91	13	several	several	ADJ
fnp-5848	91	14	studies	study	NOUN
fnp-5848	91	15	have	have	AUX
fnp-5848	91	16	suggested	suggest	VERB
fnp-5848	91	17	that	that	SCONJ
fnp-5848	91	18	the	the	DET
fnp-5848	91	19	incidence	incidence	ADJ
fnp-5848	91	20	rate	rate	NOUN
fnp-5848	91	21	of	of	ADP
fnp-5848	91	22	dementia	dementia	NOUN
fnp-5848	91	23	may	may	AUX
fnp-5848	91	24	be	be	AUX
fnp-5848	91	25	declining	decline	VERB
fnp-5848	91	26	,	,	PUNCT
fnp-5848	91	27	offering	offer	VERB
fnp-5848	91	28	hope	hope	NOUN
fnp-5848	91	29	that	that	PRON
fnp-5848	91	30	improved	improve	VERB
fnp-5848	91	31	healthcare	healthcare	NOUN
fnp-5848	91	32	and	and	CCONJ
fnp-5848	91	33	lifestyle	lifestyle	NOUN
fnp-5848	91	34	factors	factor	NOUN
fnp-5848	91	35	are	be	AUX
fnp-5848	91	36	influencing	influence	VERB
fnp-5848	91	37	this	this	DET
fnp-5848	91	38	global	global	ADJ
fnp-5848	91	39	challenge	challenge	NOUN
fnp-5848	91	40	.	.	PUNCT
fnp-5848	92	1	however	however	ADV
fnp-5848	92	2	,	,	PUNCT
fnp-5848	92	3	dementia	dementia	NOUN
fnp-5848	92	4	remains	remain	VERB
fnp-5848	92	5	a	a	DET
fnp-5848	92	6	highly	highly	ADV
fnp-5848	92	7	complex	complex	ADJ
fnp-5848	92	8	disease	disease	NOUN
fnp-5848	92	9	with	with	ADP
fnp-5848	92	10	multiple	multiple	ADJ
fnp-5848	92	11	underlying	underlying	ADJ
fnp-5848	92	12	causes	cause	NOUN
fnp-5848	92	13	that	that	PRON
fnp-5848	92	14	are	be	AUX
fnp-5848	92	15	difficult	difficult	ADJ
fnp-5848	92	16	to	to	PART
fnp-5848	92	17	diagnose	diagnose	VERB
fnp-5848	92	18	in	in	ADP
fnp-5848	92	19	the	the	DET
fnp-5848	92	20	clinical	clinical	ADJ
fnp-5848	92	21	setting	setting	NOUN
fnp-5848	92	22	.	.	PUNCT
fnp-5848	93	1	both	both	CCONJ
fnp-5848	93	2	genetic	genetic	ADJ
fnp-5848	93	3	and	and	CCONJ
fnp-5848	93	4	environmental	environmental	ADJ
fnp-5848	93	5	risk	risk	NOUN
fnp-5848	93	6	factors	factor	NOUN
fnp-5848	93	7	play	play	VERB
fnp-5848	93	8	significant	significant	ADJ
fnp-5848	93	9	roles	role	NOUN
fnp-5848	93	10	in	in	ADP
fnp-5848	93	11	the	the	DET
fnp-5848	93	12	development	development	NOUN
fnp-5848	93	13	of	of	ADP
fnp-5848	93	14	dementia	dementia	NOUN
fnp-5848	93	15	,	,	PUNCT
fnp-5848	93	16	and	and	CCONJ
fnp-5848	93	17	understanding	understand	VERB
fnp-5848	93	18	their	their	PRON
fnp-5848	93	19	interplay	interplay	NOUN
fnp-5848	93	20	over	over	ADP
fnp-5848	93	21	time	time	NOUN
fnp-5848	93	22	is	be	AUX
fnp-5848	93	23	critical	critical	ADJ
fnp-5848	93	24	.	.	PUNCT
fnp-5848	94	1	across	across	ADP
fnp-5848	94	2	birth	birth	NOUN
fnp-5848	94	3	epochs	epoch	NOUN
fnp-5848	94	4	,	,	PUNCT
fnp-5848	94	5	an	an	DET
fnp-5848	94	6	enormous	enormous	ADJ
fnp-5848	94	7	number	number	NOUN
fnp-5848	94	8	of	of	ADP
fnp-5848	94	9	factors	factor	NOUN
fnp-5848	94	10	have	have	AUX
fnp-5848	94	11	changed	change	VERB
fnp-5848	94	12	,	,	PUNCT
fnp-5848	94	13	any	any	PRON
fnp-5848	94	14	of	of	ADP
fnp-5848	94	15	which	which	PRON
fnp-5848	94	16	could	could	AUX
fnp-5848	94	17	potentially	potentially	ADV
fnp-5848	94	18	influence	influence	VERB
fnp-5848	94	19	dementia	dementia	NOUN
fnp-5848	94	20	risk	risk	NOUN
fnp-5848	94	21	.	.	PUNCT
fnp-5848	95	1	these	these	PRON
fnp-5848	95	2	include	include	VERB
fnp-5848	95	3	environmental	environmental	ADJ
fnp-5848	95	4	exposures	exposure	NOUN
fnp-5848	95	5	(	(	PUNCT
fnp-5848	95	6	e.g.	e.g.	ADV
fnp-5848	95	7	,	,	PUNCT
fnp-5848	95	8	air	air	NOUN
fnp-5848	95	9	pollution	pollution	NOUN
fnp-5848	95	10	,	,	PUNCT
fnp-5848	95	11	pesticides	pesticide	NOUN
fnp-5848	95	12	)	)	PUNCT
fnp-5848	95	13	,	,	PUNCT
fnp-5848	95	14	infectious	infectious	ADJ
fnp-5848	95	15	diseases	disease	NOUN
fnp-5848	95	16	(	(	PUNCT
fnp-5848	95	17	e.g.	e.g.	ADV
fnp-5848	95	18	,	,	PUNCT
fnp-5848	95	19	herpes	herpe	NOUN
fnp-5848	95	20	,	,	PUNCT
fnp-5848	95	21	hiv	hiv	PROPN
fnp-5848	95	22	)	)	PUNCT
fnp-5848	95	23	,	,	PUNCT
fnp-5848	95	24	socioeconomic	socioeconomic	ADJ
fnp-5848	95	25	shifts	shift	NOUN
fnp-5848	95	26	(	(	PUNCT
fnp-5848	95	27	e.g.	e.g.	ADV
fnp-5848	95	28	,	,	PUNCT
fnp-5848	95	29	malnutrition	malnutrition	NOUN
fnp-5848	95	30	)	)	PUNCT
fnp-5848	95	31	,	,	PUNCT
fnp-5848	95	32	medical	medical	ADJ
fnp-5848	95	33	advances	advance	NOUN
fnp-5848	95	34	,	,	PUNCT
fnp-5848	95	35	dietary	dietary	ADJ
fnp-5848	95	36	and	and	CCONJ
fnp-5848	95	37	lifestyle	lifestyle	NOUN
fnp-5848	95	38	trends	trend	NOUN
fnp-5848	95	39	,	,	PUNCT
fnp-5848	95	40	technological	technological	ADJ
fnp-5848	95	41	changes	change	NOUN
fnp-5848	95	42	,	,	PUNCT
fnp-5848	95	43	genetic	genetic	ADJ
fnp-5848	95	44	variations	variation	NOUN
fnp-5848	95	45	,	,	PUNCT
fnp-5848	95	46	access	access	NOUN
fnp-5848	95	47	to	to	ADP
fnp-5848	95	48	healthcare	healthcare	PROPN
fnp-5848	95	49	,	,	PUNCT
fnp-5848	95	50	longevity	longevity	NOUN
fnp-5848	95	51	,	,	PUNCT
fnp-5848	95	52	and	and	CCONJ
fnp-5848	95	53	even	even	ADV
fnp-5848	95	54	epigenetic	epigenetic	ADJ
fnp-5848	95	55	modifications	modification	NOUN
fnp-5848	95	56	.	.	PUNCT
fnp-5848	96	1	despite	despite	SCONJ
fnp-5848	96	2	recent	recent	ADJ
fnp-5848	96	3	findings	finding	NOUN
fnp-5848	96	4	pointing	point	VERB
fnp-5848	96	5	toward	toward	ADP
fnp-5848	96	6	declining	decline	VERB
fnp-5848	96	7	dementia	dementia	NOUN
fnp-5848	96	8	rates	rate	NOUN
fnp-5848	96	9	,	,	PUNCT
fnp-5848	96	10	the	the	DET
fnp-5848	96	11	precise	precise	ADJ
fnp-5848	96	12	neuropathological	neuropathological	ADJ
fnp-5848	96	13	underpinnings	underpinning	NOUN
fnp-5848	96	14	of	of	ADP
fnp-5848	96	15	these	these	DET
fnp-5848	96	16	trends	trend	NOUN
fnp-5848	96	17	remain	remain	VERB
fnp-5848	96	18	unclear	unclear	ADJ
fnp-5848	96	19	.	.	PUNCT
fnp-5848	97	1	this	this	DET
fnp-5848	97	2	gap	gap	NOUN
fnp-5848	97	3	in	in	ADP
fnp-5848	97	4	knowledge	knowledge	NOUN
fnp-5848	97	5	presents	present	VERB
fnp-5848	97	6	a	a	DET
fnp-5848	97	7	major	major	ADJ
fnp-5848	97	8	barrier	barrier	NOUN
fnp-5848	97	9	to	to	ADP
fnp-5848	97	10	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	97	11	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	97	12	free	free	ADJ
fnp-5848	97	13	neuropathology	neuropathology	NOUN
fnp-5848	97	14	5:31	5:31	NUM
fnp-5848	97	15	(	(	PUNCT
fnp-5848	97	16	2024	2024	NUM
fnp-5848	97	17	)	)	PUNCT
fnp-5848	97	18	john	john	PROPN
fnp-5848	97	19	f.	f.	PROPN
fnp-5848	97	20	crary	crary	PROPN
fnp-5848	97	21	doi	doi	PROPN
fnp-5848	97	22	:	:	PUNCT
fnp-5848	97	23	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	97	24	page	page	NOUN
fnp-5848	97	25	7	7	NUM
fnp-5848	97	26	of	of	ADP
fnp-5848	97	27	12	12	NUM
fnp-5848	97	28	figure	figure	NOUN
fnp-5848	97	29	 	 	SPACE
fnp-5848	97	30	4	4	NUM
fnp-5848	97	31	.	.	PUNCT
fnp-5848	98	1	the	the	DET
fnp-5848	98	2	“	"	PUNCT
fnp-5848	98	3	histoage	histoage	NOUN
fnp-5848	98	4	”	"	PUNCT
fnp-5848	98	5	pipeline	pipeline	NOUN
fnp-5848	98	6	.	.	PUNCT
fnp-5848	99	1	a.	a.	PROPN
fnp-5848	99	2	digital	digital	PROPN
fnp-5848	99	3	whole	whole	ADJ
fnp-5848	99	4	slide	slide	NOUN
fnp-5848	99	5	images	image	NOUN
fnp-5848	99	6	were	be	AUX
fnp-5848	99	7	broken	break	VERB
fnp-5848	99	8	up	up	ADP
fnp-5848	99	9	into	into	ADP
fnp-5848	99	10	smaller	small	ADJ
fnp-5848	99	11	tiles	tile	NOUN
fnp-5848	99	12	,	,	PUNCT
fnp-5848	99	13	then	then	ADV
fnp-5848	99	14	run	run	VERB
fnp-5848	99	15	through	through	ADP
fnp-5848	99	16	a	a	DET
fnp-5848	99	17	neural	neural	ADJ
fnp-5848	99	18	network	network	NOUN
fnp-5848	99	19	that	that	PRON
fnp-5848	99	20	extracts	extract	VERB
fnp-5848	99	21	features	feature	NOUN
fnp-5848	99	22	.	.	PUNCT
fnp-5848	100	1	these	these	DET
fnp-5848	100	2	features	feature	NOUN
fnp-5848	100	3	were	be	AUX
fnp-5848	100	4	linked	link	VERB
fnp-5848	100	5	to	to	ADP
fnp-5848	100	6	adjoining	adjoining	ADJ
fnp-5848	100	7	tiles	tile	NOUN
fnp-5848	100	8	using	use	VERB
fnp-5848	100	9	graph	graph	NOUN
fnp-5848	100	10	structure	structure	NOUN
fnp-5848	100	11	.	.	PUNCT
fnp-5848	101	1	b.	b.	PROPN
fnp-5848	102	1	the	the	DET
fnp-5848	102	2	features	feature	NOUN
fnp-5848	102	3	were	be	AUX
fnp-5848	102	4	then	then	ADV
fnp-5848	102	5	used	use	VERB
fnp-5848	102	6	to	to	PART
fnp-5848	102	7	train	train	VERB
fnp-5848	102	8	a	a	DET
fnp-5848	102	9	new	new	ADJ
fnp-5848	102	10	neural	neural	ADJ
fnp-5848	102	11	network	network	NOUN
fnp-5848	102	12	that	that	PRON
fnp-5848	102	13	predicted	predict	VERB
fnp-5848	102	14	age	age	NOUN
fnp-5848	102	15	,	,	PUNCT
fnp-5848	102	16	which	which	PRON
fnp-5848	102	17	was	be	AUX
fnp-5848	102	18	compared	compare	VERB
fnp-5848	102	19	to	to	ADP
fnp-5848	102	20	chronological	chronological	ADJ
fnp-5848	102	21	age	age	NOUN
fnp-5848	102	22	to	to	PART
fnp-5848	102	23	estimate	estimate	VERB
fnp-5848	102	24	age	age	NOUN
fnp-5848	102	25	acceleration	acceleration	NOUN
fnp-5848	102	26	.	.	PUNCT
fnp-5848	103	1	reproduced	reproduce	VERB
fnp-5848	103	2	under	under	ADP
fnp-5848	103	3	the	the	DET
fnp-5848	103	4	creative	creative	ADJ
fnp-5848	103	5	commons	common	NOUN
fnp-5848	103	6	attribution	attribution	NOUN
fnp-5848	103	7	4.0	4.0	NUM
fnp-5848	103	8	international	international	ADJ
fnp-5848	103	9	license	license	NOUN
fnp-5848	103	10	(	(	PUNCT
fnp-5848	103	11	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	103	12	)	)	PUNCT
fnp-5848	103	13	.	.	PUNCT
fnp-5848	104	1	developing	develop	VERB
fnp-5848	104	2	targeted	target	VERB
fnp-5848	104	3	interventions	intervention	NOUN
fnp-5848	104	4	and	and	CCONJ
fnp-5848	104	5	public	public	ADJ
fnp-5848	104	6	health	health	NOUN
fnp-5848	104	7	strategies	strategy	NOUN
fnp-5848	104	8	,	,	PUNCT
fnp-5848	104	9	particularly	particularly	ADV
fnp-5848	104	10	as	as	SCONJ
fnp-5848	104	11	the	the	DET
fnp-5848	104	12	population	population	NOUN
fnp-5848	104	13	continues	continue	VERB
fnp-5848	104	14	to	to	PART
fnp-5848	104	15	age	age	NOUN
fnp-5848	104	16	and	and	CCONJ
fnp-5848	104	17	the	the	DET
fnp-5848	104	18	global	global	ADJ
fnp-5848	104	19	burden	burden	NOUN
fnp-5848	104	20	of	of	ADP
fnp-5848	104	21	dementia	dementia	NOUN
fnp-5848	104	22	grows	grow	VERB
fnp-5848	104	23	.	.	PUNCT
fnp-5848	105	1	a	a	DET
fnp-5848	105	2	study	study	NOUN
fnp-5848	105	3	by	by	ADP
fnp-5848	105	4	grodstein	grodstein	PROPN
fnp-5848	105	5	et	et	PROPN
fnp-5848	105	6	al	al	PROPN
fnp-5848	105	7	.	.	PROPN
fnp-5848	105	8	published	publish	VERB
fnp-5848	105	9	in	in	ADP
fnp-5848	105	10	jama	jama	PROPN
fnp-5848	105	11	neurology	neurology	NOUN
fnp-5848	105	12	examines	examine	VERB
fnp-5848	105	13	trends	trend	NOUN
fnp-5848	105	14	in	in	ADP
fnp-5848	105	15	postmortem	postmortem	NOUN
fnp-5848	105	16	neurodegenerative	neurodegenerative	ADJ
fnp-5848	105	17	and	and	CCONJ
fnp-5848	105	18	cerebrovascular	cerebrovascular	ADJ
fnp-5848	105	19	neuropathologies	neuropathologie	NOUN
fnp-5848	105	20	over	over	ADP
fnp-5848	105	21	25	25	NUM
fnp-5848	105	22	years	year	NOUN
fnp-5848	105	23	using	use	VERB
fnp-5848	105	24	data	datum	NOUN
fnp-5848	105	25	from	from	ADP
fnp-5848	105	26	the	the	DET
fnp-5848	105	27	religious	religious	ADJ
fnp-5848	105	28	orders	order	NOUN
fnp-5848	105	29	study	study	VERB
fnp-5848	105	30	and	and	CCONJ
fnp-5848	105	31	the	the	DET
fnp-5848	105	32	rush	rush	NOUN
fnp-5848	105	33	memory	memory	NOUN
fnp-5848	105	34	and	and	CCONJ
fnp-5848	105	35	aging	age	VERB
fnp-5848	105	36	project	project	NOUN
fnp-5848	105	37	(	(	PUNCT
fnp-5848	105	38	grodstein	grodstein	NOUN
fnp-5848	105	39	et	et	PROPN
fnp-5848	105	40	al	al	PROPN
fnp-5848	105	41	.	.	PROPN
fnp-5848	105	42	,	,	PUNCT
fnp-5848	105	43	2023	2023	NUM
fnp-5848	105	44	)	)	PUNCT
fnp-5848	105	45	.	.	PUNCT
fnp-5848	106	1	this	this	DET
fnp-5848	106	2	comprehensive	comprehensive	ADJ
fnp-5848	106	3	investigation	investigation	NOUN
fnp-5848	106	4	includes	include	VERB
fnp-5848	106	5	1,554	1,554	NUM
fnp-5848	106	6	deceased	deceased	ADJ
fnp-5848	106	7	participants	participant	NOUN
fnp-5848	106	8	with	with	ADP
fnp-5848	106	9	complete	complete	ADJ
fnp-5848	106	10	brain	brain	NOUN
fnp-5848	106	11	autopsies	autopsy	NOUN
fnp-5848	106	12	and	and	CCONJ
fnp-5848	106	13	neuropathologic	neuropathologic	ADJ
fnp-5848	106	14	evaluations	evaluation	NOUN
fnp-5848	106	15	.	.	PUNCT
fnp-5848	107	1	the	the	DET
fnp-5848	107	2	study	study	NOUN
fnp-5848	107	3	analyzes	analyze	VERB
fnp-5848	107	4	four	four	NUM
fnp-5848	107	5	birth	birth	NOUN
fnp-5848	107	6	cohorts	cohort	NOUN
fnp-5848	107	7	spanning	span	VERB
fnp-5848	107	8	from	from	ADP
fnp-5848	107	9	1905	1905	NUM
fnp-5848	107	10	to	to	ADP
fnp-5848	107	11	1930	1930	NUM
fnp-5848	107	12	to	to	PART
fnp-5848	107	13	assess	assess	VERB
fnp-5848	107	14	changes	change	NOUN
fnp-5848	107	15	in	in	ADP
fnp-5848	107	16	neuropathological	neuropathological	ADJ
fnp-5848	107	17	outcomes	outcome	NOUN
fnp-5848	107	18	such	such	ADJ
fnp-5848	107	19	as	as	ADP
fnp-5848	107	20	alzheimer	alzheimer	PROPN
fnp-5848	107	21	's	's	PART
fnp-5848	107	22	disease	disease	NOUN
fnp-5848	107	23	(	(	PUNCT
fnp-5848	107	24	ad	ad	NOUN
fnp-5848	107	25	)	)	PUNCT
fnp-5848	107	26	,	,	PUNCT
fnp-5848	107	27	amyloid	amyloid	NOUN
fnp-5848	107	28	load	load	NOUN
fnp-5848	107	29	,	,	PUNCT
fnp-5848	107	30	tau	tau	PROPN
fnp-5848	107	31	tangles	tangle	NOUN
fnp-5848	107	32	,	,	PUNCT
fnp-5848	107	33	neocortical	neocortical	ADJ
fnp-5848	107	34	lewy	lewy	ADJ
fnp-5848	107	35	bodies	body	NOUN
fnp-5848	107	36	,	,	PUNCT
fnp-5848	107	37	limbic	limbic	NOUN
fnp-5848	107	38	-	-	PUNCT
fnp-5848	107	39	predominant	predominant	ADJ
fnp-5848	107	40	age	age	NOUN
fnp-5848	107	41	-	-	PUNCT
fnp-5848	107	42	related	relate	VERB
fnp-5848	107	43	tdp-43	tdp-43	NOUN
fnp-5848	107	44	encephalopathy	encephalopathy	NOUN
fnp-5848	107	45	,	,	PUNCT
fnp-5848	107	46	atherosclerosis	atherosclerosis	NOUN
fnp-5848	107	47	,	,	PUNCT
fnp-5848	107	48	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-5848	107	49	,	,	PUNCT
fnp-5848	107	50	and	and	CCONJ
fnp-5848	107	51	brain	brain	NOUN
fnp-5848	107	52	infarcts	infarct	NOUN
fnp-5848	107	53	.	.	PUNCT
fnp-5848	108	1	strikingly	strikingly	ADV
fnp-5848	108	2	,	,	PUNCT
fnp-5848	108	3	they	they	PRON
fnp-5848	108	4	found	find	VERB
fnp-5848	108	5	no	no	DET
fnp-5848	108	6	significant	significant	ADJ
fnp-5848	108	7	differences	difference	NOUN
fnp-5848	108	8	in	in	ADP
fnp-5848	108	9	the	the	DET
fnp-5848	108	10	prevalence	prevalence	NOUN
fnp-5848	108	11	of	of	ADP
fnp-5848	108	12	pathologic	pathologic	ADJ
fnp-5848	108	13	ad	ad	NOUN
fnp-5848	108	14	diagnoses	diagnosis	NOUN
fnp-5848	108	15	across	across	ADP
fnp-5848	108	16	birth	birth	NOUN
fnp-5848	108	17	cohorts	cohort	NOUN
fnp-5848	108	18	,	,	PUNCT
fnp-5848	108	19	with	with	ADP
fnp-5848	108	20	age	age	NOUN
fnp-5848	108	21	-	-	PUNCT
fnp-5848	108	22	standardized	standardize	VERB
fnp-5848	108	23	prevalence	prevalence	NOUN
fnp-5848	108	24	ranging	range	VERB
fnp-5848	108	25	between	between	ADP
fnp-5848	108	26	62	62	NUM
fnp-5848	108	27	 	 	SPACE
fnp-5848	108	28	%	%	NOUN
fnp-5848	108	29	and	and	CCONJ
fnp-5848	108	30	68	68	NUM
fnp-5848	108	31	 	 	SPACE
fnp-5848	108	32	%	%	NOUN
fnp-5848	108	33	.	.	PUNCT
fnp-5848	109	1	similarly	similarly	ADV
fnp-5848	109	2	,	,	PUNCT
fnp-5848	109	3	there	there	PRON
fnp-5848	109	4	were	be	VERB
fnp-5848	109	5	no	no	DET
fnp-5848	109	6	marked	mark	VERB
fnp-5848	109	7	changes	change	NOUN
fnp-5848	109	8	in	in	ADP
fnp-5848	109	9	global	global	ADJ
fnp-5848	109	10	ad	ad	NOUN
fnp-5848	109	11	pathology	pathology	NOUN
fnp-5848	109	12	or	or	CCONJ
fnp-5848	109	13	other	other	ADJ
fnp-5848	109	14	neurodegenerative	neurodegenerative	ADJ
fnp-5848	109	15	pathologies	pathology	NOUN
fnp-5848	109	16	over	over	ADP
fnp-5848	109	17	time	time	NOUN
fnp-5848	109	18	.	.	PUNCT
fnp-5848	110	1	however	however	ADV
fnp-5848	110	2	,	,	PUNCT
fnp-5848	110	3	an	an	DET
fnp-5848	110	4	increase	increase	NOUN
fnp-5848	110	5	in	in	ADP
fnp-5848	110	6	tau	tau	PROPN
fnp-5848	110	7	tangle	tangle	NOUN
fnp-5848	110	8	density	density	NOUN
fnp-5848	110	9	was	be	AUX
fnp-5848	110	10	noted	note	VERB
fnp-5848	110	11	in	in	ADP
fnp-5848	110	12	more	more	ADV
fnp-5848	110	13	recent	recent	ADJ
fnp-5848	110	14	birth	birth	NOUN
fnp-5848	110	15	cohorts	cohort	NOUN
fnp-5848	110	16	,	,	PUNCT
fnp-5848	110	17	suggesting	suggest	VERB
fnp-5848	110	18	a	a	DET
fnp-5848	110	19	potential	potential	ADJ
fnp-5848	110	20	rise	rise	NOUN
fnp-5848	110	21	in	in	ADP
fnp-5848	110	22	this	this	DET
fnp-5848	110	23	specific	specific	ADJ
fnp-5848	110	24	pathology	pathology	NOUN
fnp-5848	110	25	.	.	PUNCT
fnp-5848	111	1	in	in	ADP
fnp-5848	111	2	contrast	contrast	NOUN
fnp-5848	111	3	,	,	PUNCT
fnp-5848	111	4	the	the	DET
fnp-5848	111	5	authors	author	NOUN
fnp-5848	111	6	found	find	VERB
fnp-5848	111	7	a	a	DET
fnp-5848	111	8	dramatic	dramatic	ADJ
fnp-5848	111	9	decrease	decrease	NOUN
fnp-5848	111	10	in	in	ADP
fnp-5848	111	11	cerebrovascular	cerebrovascular	ADJ
fnp-5848	111	12	pathologies	pathology	NOUN
fnp-5848	111	13	,	,	PUNCT
fnp-5848	111	14	particularly	particularly	ADV
fnp-5848	111	15	atherosclerosis	atherosclerosis	NOUN
fnp-5848	111	16	and	and	CCONJ
fnp-5848	111	17	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-5848	111	18	,	,	PUNCT
fnp-5848	111	19	over	over	ADP
fnp-5848	111	20	the	the	DET
fnp-5848	111	21	observed	observed	ADJ
fnp-5848	111	22	period	period	NOUN
fnp-5848	111	23	.	.	PUNCT
fnp-5848	112	1	age	age	NOUN
fnp-5848	112	2	-	-	PUNCT
fnp-5848	112	3	standardized	standardize	VERB
fnp-5848	112	4	prevalence	prevalence	NOUN
fnp-5848	112	5	of	of	ADP
fnp-5848	112	6	moderate	moderate	ADJ
fnp-5848	112	7	to	to	ADP
fnp-5848	112	8	severe	severe	ADJ
fnp-5848	112	9	atherosclerosis	atherosclerosis	NOUN
fnp-5848	112	10	decreased	decrease	VERB
fnp-5848	112	11	from	from	ADP
fnp-5848	112	12	54	54	NUM
fnp-5848	112	13	 	 	SPACE
fnp-5848	112	14	%	%	NOUN
fnp-5848	112	15	in	in	ADP
fnp-5848	112	16	the	the	DET
fnp-5848	112	17	earliest	early	ADJ
fnp-5848	112	18	cohort	cohort	NOUN
fnp-5848	112	19	(	(	PUNCT
fnp-5848	112	20	1905–1914	1905–1914	NUM
fnp-5848	112	21	)	)	PUNCT
fnp-5848	112	22	to	to	ADP
fnp-5848	112	23	22	22	NUM
fnp-5848	112	24	 	 	SPACE
fnp-5848	112	25	%	%	NOUN
fnp-5848	112	26	in	in	ADP
fnp-5848	112	27	the	the	DET
fnp-5848	112	28	latest	late	ADJ
fnp-5848	112	29	cohort	cohort	NOUN
fnp-5848	112	30	(	(	PUNCT
fnp-5848	112	31	1925–1930	1925–1930	NUM
fnp-5848	112	32	)	)	PUNCT
fnp-5848	112	33	.	.	PUNCT
fnp-5848	113	1	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-5848	113	2	showed	show	VERB
fnp-5848	113	3	a	a	DET
fnp-5848	113	4	similar	similar	ADJ
fnp-5848	113	5	decline	decline	NOUN
fnp-5848	113	6	.	.	PUNCT
fnp-5848	114	1	these	these	DET
fnp-5848	114	2	findings	finding	NOUN
fnp-5848	114	3	highlight	highlight	VERB
fnp-5848	114	4	the	the	DET
fnp-5848	114	5	impact	impact	NOUN
fnp-5848	114	6	of	of	ADP
fnp-5848	114	7	improved	improved	ADJ
fnp-5848	114	8	vascular	vascular	ADJ
fnp-5848	114	9	health	health	NOUN
fnp-5848	114	10	on	on	ADP
fnp-5848	114	11	brain	brain	NOUN
fnp-5848	114	12	aging	aging	NOUN
fnp-5848	114	13	and	and	CCONJ
fnp-5848	114	14	suggest	suggest	VERB
fnp-5848	114	15	that	that	SCONJ
fnp-5848	114	16	reductions	reduction	NOUN
fnp-5848	114	17	in	in	ADP
fnp-5848	114	18	clinical	clinical	ADJ
fnp-5848	114	19	dementia	dementia	NOUN
fnp-5848	114	20	observed	observe	VERB
fnp-5848	114	21	in	in	ADP
fnp-5848	114	22	other	other	ADJ
fnp-5848	114	23	studies	study	NOUN
fnp-5848	114	24	may	may	AUX
fnp-5848	114	25	be	be	AUX
fnp-5848	114	26	associated	associate	VERB
fnp-5848	114	27	with	with	ADP
fnp-5848	114	28	enhanced	enhanced	ADJ
fnp-5848	114	29	resilience	resilience	NOUN
fnp-5848	114	30	to	to	ADP
fnp-5848	114	31	neuropathology	neuropathology	NOUN
fnp-5848	114	32	rather	rather	ADV
fnp-5848	114	33	than	than	ADP
fnp-5848	114	34	a	a	DET
fnp-5848	114	35	decrease	decrease	NOUN
fnp-5848	114	36	in	in	ADP
fnp-5848	114	37	the	the	DET
fnp-5848	114	38	underlying	underlying	ADJ
fnp-5848	114	39	neurodegenerative	neurodegenerative	ADJ
fnp-5848	114	40	pathologies	pathology	NOUN
fnp-5848	114	41	.	.	PUNCT
fnp-5848	115	1	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	115	2	free	free	ADJ
fnp-5848	115	3	neuropathology	neuropathology	NOUN
fnp-5848	115	4	5:31	5:31	NUM
fnp-5848	115	5	(	(	PUNCT
fnp-5848	115	6	2024	2024	NUM
fnp-5848	115	7	)	)	PUNCT
fnp-5848	115	8	john	john	PROPN
fnp-5848	115	9	f.	f.	PROPN
fnp-5848	115	10	crary	crary	PROPN
fnp-5848	115	11	doi	doi	PROPN
fnp-5848	115	12	:	:	PUNCT
fnp-5848	115	13	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	115	14	page	page	NOUN
fnp-5848	115	15	8	8	NUM
fnp-5848	115	16	of	of	ADP
fnp-5848	115	17	12	12	NUM
fnp-5848	115	18	additionally	additionally	ADV
fnp-5848	115	19	,	,	PUNCT
fnp-5848	115	20	the	the	DET
fnp-5848	115	21	study	study	NOUN
fnp-5848	115	22	emphasizes	emphasize	VERB
fnp-5848	115	23	the	the	DET
fnp-5848	115	24	importance	importance	NOUN
fnp-5848	115	25	of	of	ADP
fnp-5848	115	26	considering	consider	VERB
fnp-5848	115	27	both	both	CCONJ
fnp-5848	115	28	neurodegenerative	neurodegenerative	ADJ
fnp-5848	115	29	and	and	CCONJ
fnp-5848	115	30	cerebrovascular	cerebrovascular	ADJ
fnp-5848	115	31	factors	factor	NOUN
fnp-5848	115	32	in	in	ADP
fnp-5848	115	33	understanding	understand	VERB
fnp-5848	115	34	dementia	dementia	NOUN
fnp-5848	115	35	trends	trend	NOUN
fnp-5848	115	36	and	and	CCONJ
fnp-5848	115	37	developing	develop	VERB
fnp-5848	115	38	public	public	ADJ
fnp-5848	115	39	health	health	NOUN
fnp-5848	115	40	strategies	strategy	NOUN
fnp-5848	115	41	to	to	PART
fnp-5848	115	42	address	address	VERB
fnp-5848	115	43	the	the	DET
fnp-5848	115	44	growing	grow	VERB
fnp-5848	115	45	aging	age	VERB
fnp-5848	115	46	population	population	NOUN
fnp-5848	115	47	.	.	PUNCT
fnp-5848	116	1	the	the	DET
fnp-5848	116	2	results	result	NOUN
fnp-5848	116	3	underscore	underscore	VERB
fnp-5848	116	4	the	the	DET
fnp-5848	116	5	need	need	NOUN
fnp-5848	116	6	for	for	ADP
fnp-5848	116	7	continued	continued	ADJ
fnp-5848	116	8	efforts	effort	NOUN
fnp-5848	116	9	to	to	PART
fnp-5848	116	10	improve	improve	VERB
fnp-5848	116	11	vascular	vascular	ADJ
fnp-5848	116	12	health	health	NOUN
fnp-5848	116	13	as	as	ADP
fnp-5848	116	14	a	a	DET
fnp-5848	116	15	means	means	NOUN
fnp-5848	116	16	to	to	PART
fnp-5848	116	17	mitigate	mitigate	VERB
fnp-5848	116	18	the	the	DET
fnp-5848	116	19	impact	impact	NOUN
fnp-5848	116	20	of	of	ADP
fnp-5848	116	21	dementia	dementia	NOUN
fnp-5848	116	22	.	.	PUNCT
fnp-5848	117	1	7	7	X
fnp-5848	117	2	.	.	PUNCT
fnp-5848	117	3	 	 	SPACE
fnp-5848	117	4	microglia	microglia	PROPN
fnp-5848	117	5	-	-	PUNCT
fnp-5848	117	6	t	t	NOUN
fnp-5848	117	7	cell	cell	NOUN
fnp-5848	117	8	interaction	interaction	NOUN
fnp-5848	117	9	in	in	ADP
fnp-5848	117	10	alzheimer	alzheimer	PROPN
fnp-5848	117	11	’s	’s	PART
fnp-5848	117	12	disease	disease	NOUN
fnp-5848	117	13	and	and	CCONJ
fnp-5848	117	14	tauopathy	tauopathy	VERB
fnp-5848	117	15	the	the	DET
fnp-5848	117	16	immune	immune	ADJ
fnp-5848	117	17	system	system	NOUN
fnp-5848	117	18	's	's	PART
fnp-5848	117	19	involvement	involvement	NOUN
fnp-5848	117	20	in	in	ADP
fnp-5848	117	21	neurodegeneration	neurodegeneration	NOUN
fnp-5848	117	22	continues	continue	VERB
fnp-5848	117	23	to	to	PART
fnp-5848	117	24	gain	gain	VERB
fnp-5848	117	25	increasing	increase	VERB
fnp-5848	117	26	attention	attention	NOUN
fnp-5848	117	27	,	,	PUNCT
fnp-5848	117	28	with	with	ADP
fnp-5848	117	29	compelling	compelling	ADJ
fnp-5848	117	30	evidence	evidence	NOUN
fnp-5848	117	31	pointing	point	VERB
fnp-5848	117	32	to	to	ADP
fnp-5848	117	33	its	its	PRON
fnp-5848	117	34	critical	critical	ADJ
fnp-5848	117	35	role	role	NOUN
fnp-5848	117	36	in	in	ADP
fnp-5848	117	37	disease	disease	NOUN
fnp-5848	117	38	progression	progression	NOUN
fnp-5848	117	39	.	.	PUNCT
fnp-5848	118	1	the	the	DET
fnp-5848	118	2	innate	innate	ADJ
fnp-5848	118	3	immune	immune	ADJ
fnp-5848	118	4	system	system	NOUN
fnp-5848	118	5	,	,	PUNCT
fnp-5848	118	6	particularly	particularly	ADV
fnp-5848	118	7	through	through	ADP
fnp-5848	118	8	the	the	DET
fnp-5848	118	9	activation	activation	NOUN
fnp-5848	118	10	of	of	ADP
fnp-5848	118	11	microglia	microglia	NOUN
fnp-5848	118	12	,	,	PUNCT
fnp-5848	118	13	has	have	AUX
fnp-5848	118	14	been	be	AUX
fnp-5848	118	15	at	at	ADP
fnp-5848	118	16	the	the	DET
fnp-5848	118	17	forefront	forefront	NOUN
fnp-5848	118	18	of	of	ADP
fnp-5848	118	19	research	research	NOUN
fnp-5848	118	20	efforts	effort	NOUN
fnp-5848	118	21	,	,	PUNCT
fnp-5848	118	22	with	with	ADP
fnp-5848	118	23	these	these	DET
fnp-5848	118	24	cells	cell	NOUN
fnp-5848	118	25	being	be	AUX
fnp-5848	118	26	implicated	implicate	VERB
fnp-5848	118	27	in	in	ADP
fnp-5848	118	28	the	the	DET
fnp-5848	118	29	inflammatory	inflammatory	ADJ
fnp-5848	118	30	processes	process	NOUN
fnp-5848	118	31	that	that	PRON
fnp-5848	118	32	contribute	contribute	VERB
fnp-5848	118	33	to	to	ADP
fnp-5848	118	34	neuronal	neuronal	ADJ
fnp-5848	118	35	damage	damage	NOUN
fnp-5848	118	36	.	.	PUNCT
fnp-5848	119	1	however	however	ADV
fnp-5848	119	2	,	,	PUNCT
fnp-5848	119	3	a	a	DET
fnp-5848	119	4	significant	significant	ADJ
fnp-5848	119	5	gap	gap	NOUN
fnp-5848	119	6	remains	remain	VERB
fnp-5848	119	7	in	in	ADP
fnp-5848	119	8	understanding	understand	VERB
fnp-5848	119	9	the	the	DET
fnp-5848	119	10	role	role	NOUN
fnp-5848	119	11	of	of	ADP
fnp-5848	119	12	the	the	DET
fnp-5848	119	13	adaptive	adaptive	ADJ
fnp-5848	119	14	immune	immune	ADJ
fnp-5848	119	15	system	system	NOUN
fnp-5848	119	16	,	,	PUNCT
fnp-5848	119	17	which	which	PRON
fnp-5848	119	18	,	,	PUNCT
fnp-5848	119	19	despite	despite	SCONJ
fnp-5848	119	20	being	be	AUX
fnp-5848	119	21	central	central	ADJ
fnp-5848	119	22	in	in	ADP
fnp-5848	119	23	autoimmune	autoimmune	ADJ
fnp-5848	119	24	and	and	CCONJ
fnp-5848	119	25	infectious	infectious	ADJ
fnp-5848	119	26	diseases	disease	NOUN
fnp-5848	119	27	,	,	PUNCT
fnp-5848	119	28	has	have	AUX
fnp-5848	119	29	been	be	AUX
fnp-5848	119	30	comparatively	comparatively	ADV
fnp-5848	119	31	understudied	understudied	ADJ
fnp-5848	119	32	in	in	ADP
fnp-5848	119	33	neurodegenerative	neurodegenerative	ADJ
fnp-5848	119	34	disorders	disorder	NOUN
fnp-5848	119	35	.	.	PUNCT
fnp-5848	120	1	t	t	NOUN
fnp-5848	120	2	cells	cell	NOUN
fnp-5848	120	3	,	,	PUNCT
fnp-5848	120	4	key	key	ADJ
fnp-5848	120	5	players	player	NOUN
fnp-5848	120	6	in	in	ADP
fnp-5848	120	7	the	the	DET
fnp-5848	120	8	adaptive	adaptive	ADJ
fnp-5848	120	9	immune	immune	ADJ
fnp-5848	120	10	response	response	NOUN
fnp-5848	120	11	,	,	PUNCT
fnp-5848	120	12	have	have	AUX
fnp-5848	120	13	received	receive	VERB
fnp-5848	120	14	far	far	ADV
fnp-5848	120	15	less	less	ADJ
fnp-5848	120	16	focus	focus	NOUN
fnp-5848	120	17	in	in	ADP
fnp-5848	120	18	neurodegenerative	neurodegenerative	ADJ
fnp-5848	120	19	diseases	disease	NOUN
fnp-5848	120	20	like	like	ADP
fnp-5848	120	21	alzheimer	alzheimer	NOUN
fnp-5848	120	22	's	's	PART
fnp-5848	120	23	.	.	PUNCT
fnp-5848	121	1	this	this	DET
fnp-5848	121	2	oversight	oversight	NOUN
fnp-5848	121	3	represents	represent	VERB
fnp-5848	121	4	a	a	DET
fnp-5848	121	5	critical	critical	ADJ
fnp-5848	121	6	barrier	barrier	NOUN
fnp-5848	121	7	to	to	ADP
fnp-5848	121	8	fully	fully	ADV
fnp-5848	121	9	understanding	understand	VERB
fnp-5848	121	10	the	the	DET
fnp-5848	121	11	immune	immune	NOUN
fnp-5848	121	12	-	-	PUNCT
fnp-5848	121	13	mediated	mediate	VERB
fnp-5848	121	14	mechanisms	mechanism	NOUN
fnp-5848	121	15	of	of	ADP
fnp-5848	121	16	neurodegeneration	neurodegeneration	NOUN
fnp-5848	121	17	.	.	PUNCT
fnp-5848	122	1	although	although	SCONJ
fnp-5848	122	2	not	not	PART
fnp-5848	122	3	as	as	ADV
fnp-5848	122	4	abundant	abundant	ADJ
fnp-5848	122	5	as	as	ADP
fnp-5848	122	6	in	in	ADP
fnp-5848	122	7	conditions	condition	NOUN
fnp-5848	122	8	such	such	ADJ
fnp-5848	122	9	as	as	ADP
fnp-5848	122	10	multiple	multiple	ADJ
fnp-5848	122	11	sclerosis	sclerosis	NOUN
fnp-5848	122	12	,	,	PUNCT
fnp-5848	122	13	t	t	PROPN
fnp-5848	122	14	cells	cell	NOUN
fnp-5848	122	15	may	may	AUX
fnp-5848	122	16	still	still	ADV
fnp-5848	122	17	play	play	VERB
fnp-5848	122	18	an	an	DET
fnp-5848	122	19	important	important	ADJ
fnp-5848	122	20	role	role	NOUN
fnp-5848	122	21	in	in	ADP
fnp-5848	122	22	these	these	DET
fnp-5848	122	23	diseases	disease	NOUN
fnp-5848	122	24	,	,	PUNCT
fnp-5848	122	25	offering	offer	VERB
fnp-5848	122	26	a	a	DET
fnp-5848	122	27	potential	potential	ADJ
fnp-5848	122	28	but	but	CCONJ
fnp-5848	122	29	underexplored	underexplored	ADJ
fnp-5848	122	30	therapeutic	therapeutic	ADJ
fnp-5848	122	31	target	target	NOUN
fnp-5848	122	32	.	.	PUNCT
fnp-5848	123	1	a	a	DET
fnp-5848	123	2	study	study	NOUN
fnp-5848	123	3	by	by	ADP
fnp-5848	123	4	chen	chen	PROPN
fnp-5848	123	5	et	et	PROPN
fnp-5848	123	6	al	al	PROPN
fnp-5848	123	7	.	.	PROPN
fnp-5848	124	1	at	at	ADP
fnp-5848	124	2	the	the	DET
fnp-5848	124	3	washington	washington	PROPN
fnp-5848	124	4	university	university	PROPN
fnp-5848	124	5	school	school	NOUN
fnp-5848	124	6	of	of	ADP
fnp-5848	124	7	medicine	medicine	NOUN
fnp-5848	124	8	published	publish	VERB
fnp-5848	124	9	in	in	ADP
fnp-5848	124	10	nature	nature	NOUN
fnp-5848	124	11	investigated	investigate	VERB
fnp-5848	124	12	the	the	DET
fnp-5848	124	13	relationship	relationship	NOUN
fnp-5848	124	14	between	between	ADP
fnp-5848	124	15	microglia	microglia	NOUN
fnp-5848	124	16	,	,	PUNCT
fnp-5848	124	17	t	t	NOUN
fnp-5848	124	18	cells	cell	NOUN
fnp-5848	124	19	,	,	PUNCT
fnp-5848	124	20	and	and	CCONJ
fnp-5848	124	21	tau	tau	NOUN
fnp-5848	124	22	-	-	PUNCT
fnp-5848	124	23	mediated	mediate	VERB
fnp-5848	124	24	neurodegeneration	neurodegeneration	NOUN
fnp-5848	124	25	(	(	PUNCT
fnp-5848	124	26	chen	chen	PROPN
fnp-5848	124	27	et	et	PROPN
fnp-5848	124	28	al	al	PROPN
fnp-5848	124	29	.	.	PROPN
fnp-5848	124	30	,	,	PUNCT
fnp-5848	124	31	2023	2023	NUM
fnp-5848	124	32	)	)	PUNCT
fnp-5848	124	33	.	.	PUNCT
fnp-5848	125	1	using	use	VERB
fnp-5848	125	2	mouse	mouse	NOUN
fnp-5848	125	3	models	model	NOUN
fnp-5848	125	4	of	of	ADP
fnp-5848	125	5	amyloid	amyloid	NOUN
fnp-5848	125	6	deposition	deposition	NOUN
fnp-5848	125	7	and	and	CCONJ
fnp-5848	125	8	tau	tau	PROPN
fnp-5848	125	9	aggregation	aggregation	NOUN
fnp-5848	125	10	,	,	PUNCT
fnp-5848	125	11	they	they	PRON
fnp-5848	125	12	systematically	systematically	ADV
fnp-5848	125	13	compared	compare	VERB
fnp-5848	125	14	the	the	DET
fnp-5848	125	15	immune	immune	ADJ
fnp-5848	125	16	responses	response	NOUN
fnp-5848	125	17	in	in	ADP
fnp-5848	125	18	the	the	DET
fnp-5848	125	19	brains	brain	NOUN
fnp-5848	125	20	of	of	ADP
fnp-5848	125	21	transgenic	transgenic	NOUN
fnp-5848	125	22	mice	mouse	NOUN
fnp-5848	125	23	and	and	CCONJ
fnp-5848	125	24	humans	human	NOUN
fnp-5848	125	25	,	,	PUNCT
fnp-5848	125	26	revealing	reveal	VERB
fnp-5848	125	27	that	that	SCONJ
fnp-5848	125	28	tauopathy	tauopathy	NOUN
fnp-5848	125	29	,	,	PUNCT
fnp-5848	125	30	but	but	CCONJ
fnp-5848	125	31	not	not	PART
fnp-5848	125	32	amyloid	amyloid	NOUN
fnp-5848	125	33	deposition	deposition	NOUN
fnp-5848	125	34	,	,	PUNCT
fnp-5848	125	35	triggers	trigger	VERB
fnp-5848	125	36	a	a	DET
fnp-5848	125	37	unique	unique	ADJ
fnp-5848	125	38	adaptive	adaptive	ADJ
fnp-5848	125	39	immune	immune	ADJ
fnp-5848	125	40	response	response	NOUN
fnp-5848	125	41	.	.	PUNCT
fnp-5848	126	1	depletion	depletion	NOUN
fnp-5848	126	2	of	of	ADP
fnp-5848	126	3	either	either	PRON
fnp-5848	126	4	microglia	microglia	NOUN
fnp-5848	126	5	or	or	CCONJ
fnp-5848	126	6	t	t	NOUN
fnp-5848	126	7	cells	cell	NOUN
fnp-5848	126	8	significantly	significantly	ADV
fnp-5848	126	9	blocked	block	VERB
fnp-5848	126	10	tau	tau	PROPN
fnp-5848	126	11	-	-	PUNCT
fnp-5848	126	12	mediated	mediate	VERB
fnp-5848	126	13	neurodegeneration	neurodegeneration	NOUN
fnp-5848	126	14	,	,	PUNCT
fnp-5848	126	15	suggesting	suggest	VERB
fnp-5848	126	16	a	a	DET
fnp-5848	126	17	critical	critical	ADJ
fnp-5848	126	18	role	role	NOUN
fnp-5848	126	19	these	these	DET
fnp-5848	126	20	immune	immune	ADJ
fnp-5848	126	21	cells	cell	NOUN
fnp-5848	126	22	play	play	VERB
fnp-5848	126	23	in	in	ADP
fnp-5848	126	24	the	the	DET
fnp-5848	126	25	disease	disease	NOUN
fnp-5848	126	26	process	process	NOUN
fnp-5848	126	27	.	.	PUNCT
fnp-5848	127	1	the	the	DET
fnp-5848	127	2	study	study	NOUN
fnp-5848	127	3	identified	identify	VERB
fnp-5848	127	4	a	a	DET
fnp-5848	127	5	marked	mark	VERB
fnp-5848	127	6	increase	increase	NOUN
fnp-5848	127	7	in	in	ADP
fnp-5848	127	8	t	t	NOUN
fnp-5848	127	9	cells	cell	NOUN
fnp-5848	127	10	,	,	PUNCT
fnp-5848	127	11	especially	especially	ADV
fnp-5848	127	12	cytotoxic	cytotoxic	ADJ
fnp-5848	127	13	t	t	NOUN
fnp-5848	127	14	cells	cell	NOUN
fnp-5848	127	15	,	,	PUNCT
fnp-5848	127	16	in	in	ADP
fnp-5848	127	17	regions	region	NOUN
fnp-5848	127	18	with	with	ADP
fnp-5848	127	19	tau	tau	PROPN
fnp-5848	127	20	pathology	pathology	NOUN
fnp-5848	127	21	in	in	ADP
fnp-5848	127	22	both	both	DET
fnp-5848	127	23	mice	mouse	NOUN
fnp-5848	127	24	and	and	CCONJ
fnp-5848	127	25	human	human	PROPN
fnp-5848	127	26	alzheimer	alzheimer	PROPN
fnp-5848	127	27	's	's	PART
fnp-5848	127	28	disease	disease	NOUN
fnp-5848	127	29	brains	brain	NOUN
fnp-5848	127	30	,	,	PUNCT
fnp-5848	127	31	correlating	correlate	VERB
fnp-5848	127	32	with	with	ADP
fnp-5848	127	33	neuronal	neuronal	ADJ
fnp-5848	127	34	loss	loss	NOUN
fnp-5848	127	35	and	and	CCONJ
fnp-5848	127	36	dynamic	dynamic	ADJ
fnp-5848	127	37	transformations	transformation	NOUN
fnp-5848	127	38	from	from	ADP
fnp-5848	127	39	activated	activate	VERB
fnp-5848	127	40	to	to	ADP
fnp-5848	127	41	exhausted	exhausted	ADJ
fnp-5848	127	42	states	state	NOUN
fnp-5848	127	43	.	.	PUNCT
fnp-5848	128	1	the	the	DET
fnp-5848	128	2	researchers	researcher	NOUN
fnp-5848	128	3	utilized	utilize	VERB
fnp-5848	128	4	single	single	ADJ
fnp-5848	128	5	-	-	PUNCT
fnp-5848	128	6	cell	cell	NOUN
fnp-5848	128	7	rna	rna	NOUN
fnp-5848	128	8	sequencing	sequence	VERB
fnp-5848	128	9	(	(	PUNCT
fnp-5848	128	10	scrna	scrna	NOUN
fnp-5848	128	11	-	-	PUNCT
fnp-5848	128	12	seq	seq	NOUN
fnp-5848	128	13	)	)	PUNCT
fnp-5848	128	14	and	and	CCONJ
fnp-5848	128	15	single	single	ADJ
fnp-5848	128	16	-	-	PUNCT
fnp-5848	128	17	cell	cell	NOUN
fnp-5848	128	18	tcr	tcr	NOUN
fnp-5848	128	19	sequencing	sequence	VERB
fnp-5848	128	20	(	(	PUNCT
fnp-5848	128	21	sctcrseq	sctcrseq	NOUN
fnp-5848	128	22	)	)	PUNCT
fnp-5848	128	23	to	to	PART
fnp-5848	128	24	map	map	VERB
fnp-5848	128	25	the	the	DET
fnp-5848	128	26	cellular	cellular	ADJ
fnp-5848	128	27	and	and	CCONJ
fnp-5848	128	28	molecular	molecular	ADJ
fnp-5848	128	29	signatures	signature	NOUN
fnp-5848	128	30	of	of	ADP
fnp-5848	128	31	immune	immune	ADJ
fnp-5848	128	32	cells	cell	NOUN
fnp-5848	128	33	in	in	ADP
fnp-5848	128	34	the	the	DET
fnp-5848	128	35	brain	brain	NOUN
fnp-5848	128	36	.	.	PUNCT
fnp-5848	129	1	they	they	PRON
fnp-5848	129	2	found	find	VERB
fnp-5848	129	3	that	that	SCONJ
fnp-5848	129	4	in	in	ADP
fnp-5848	129	5	tauopathy	tauopathy	NOUN
fnp-5848	129	6	,	,	PUNCT
fnp-5848	129	7	t	t	NOUN
fnp-5848	129	8	cells	cell	NOUN
fnp-5848	129	9	and	and	CCONJ
fnp-5848	129	10	microglia	microglia	NOUN
fnp-5848	129	11	formed	form	VERB
fnp-5848	129	12	an	an	DET
fnp-5848	129	13	immune	immune	ADJ
fnp-5848	129	14	hub	hub	NOUN
fnp-5848	129	15	characterized	characterize	VERB
fnp-5848	129	16	by	by	ADP
fnp-5848	129	17	increased	increase	VERB
fnp-5848	129	18	expression	expression	NOUN
fnp-5848	129	19	of	of	ADP
fnp-5848	129	20	interferon	interferon	ADJ
fnp-5848	129	21	-	-	PUNCT
fnp-5848	129	22	γ	γ	NOUN
fnp-5848	129	23	and	and	CCONJ
fnp-5848	129	24	pdcd1	pdcd1	NOUN
fnp-5848	129	25	signaling	signal	VERB
fnp-5848	129	26	pathways	pathway	NOUN
fnp-5848	129	27	.	.	PUNCT
fnp-5848	130	1	notably	notably	ADV
fnp-5848	130	2	,	,	PUNCT
fnp-5848	130	3	inhibiting	inhibit	VERB
fnp-5848	130	4	these	these	DET
fnp-5848	130	5	pathways	pathway	NOUN
fnp-5848	130	6	significantly	significantly	ADV
fnp-5848	130	7	reduced	reduce	VERB
fnp-5848	130	8	brain	brain	NOUN
fnp-5848	130	9	atrophy	atrophy	NOUN
fnp-5848	130	10	.	.	PUNCT
fnp-5848	131	1	the	the	DET
fnp-5848	131	2	study	study	NOUN
fnp-5848	131	3	also	also	ADV
fnp-5848	131	4	highlighted	highlight	VERB
fnp-5848	131	5	the	the	DET
fnp-5848	131	6	role	role	NOUN
fnp-5848	131	7	of	of	ADP
fnp-5848	131	8	microglia	microglia	NOUN
fnp-5848	131	9	in	in	ADP
fnp-5848	131	10	presenting	present	VERB
fnp-5848	131	11	antigens	antigen	NOUN
fnp-5848	131	12	to	to	ADP
fnp-5848	131	13	t	t	NOUN
fnp-5848	131	14	cells	cell	NOUN
fnp-5848	131	15	,	,	PUNCT
fnp-5848	131	16	promoting	promote	VERB
fnp-5848	131	17	their	their	PRON
fnp-5848	131	18	infiltration	infiltration	NOUN
fnp-5848	131	19	and	and	CCONJ
fnp-5848	131	20	activation	activation	NOUN
fnp-5848	131	21	.	.	PUNCT
fnp-5848	132	1	this	this	DET
fnp-5848	132	2	interaction	interaction	NOUN
fnp-5848	132	3	was	be	AUX
fnp-5848	132	4	found	find	VERB
fnp-5848	132	5	to	to	PART
fnp-5848	132	6	be	be	AUX
fnp-5848	132	7	critical	critical	ADJ
fnp-5848	132	8	in	in	ADP
fnp-5848	132	9	driving	drive	VERB
fnp-5848	132	10	neurodegeneration	neurodegeneration	NOUN
fnp-5848	132	11	,	,	PUNCT
fnp-5848	132	12	as	as	SCONJ
fnp-5848	132	13	evidenced	evidence	VERB
fnp-5848	132	14	by	by	ADP
fnp-5848	132	15	the	the	DET
fnp-5848	132	16	reduction	reduction	NOUN
fnp-5848	132	17	in	in	ADP
fnp-5848	132	18	tau	tau	PROPN
fnp-5848	132	19	pathology	pathology	NOUN
fnp-5848	132	20	and	and	CCONJ
fnp-5848	132	21	brain	brain	NOUN
fnp-5848	132	22	atrophy	atrophy	NOUN
fnp-5848	132	23	upon	upon	SCONJ
fnp-5848	132	24	depletion	depletion	NOUN
fnp-5848	132	25	of	of	ADP
fnp-5848	132	26	t	t	NOUN
fnp-5848	132	27	cells	cell	NOUN
fnp-5848	132	28	.	.	PUNCT
fnp-5848	133	1	these	these	DET
fnp-5848	133	2	findings	finding	NOUN
fnp-5848	133	3	underscore	underscore	VERB
fnp-5848	133	4	the	the	DET
fnp-5848	133	5	potential	potential	NOUN
fnp-5848	133	6	of	of	ADP
fnp-5848	133	7	targeting	target	VERB
fnp-5848	133	8	microglia	microglia	NOUN
fnp-5848	133	9	and	and	CCONJ
fnp-5848	133	10	t	t	NOUN
fnp-5848	133	11	cell	cell	NOUN
fnp-5848	133	12	interactions	interaction	NOUN
fnp-5848	133	13	as	as	ADP
fnp-5848	133	14	a	a	DET
fnp-5848	133	15	therapeutic	therapeutic	ADJ
fnp-5848	133	16	strategy	strategy	NOUN
fnp-5848	133	17	for	for	ADP
fnp-5848	133	18	tauopathies	tauopathie	NOUN
fnp-5848	133	19	and	and	CCONJ
fnp-5848	133	20	alzheimer	alzheimer	PROPN
fnp-5848	133	21	's	's	PART
fnp-5848	133	22	disease	disease	NOUN
fnp-5848	133	23	,	,	PUNCT
fnp-5848	133	24	offering	offer	VERB
fnp-5848	133	25	new	new	ADJ
fnp-5848	133	26	avenues	avenue	NOUN
fnp-5848	133	27	for	for	ADP
fnp-5848	133	28	treatment	treatment	NOUN
fnp-5848	133	29	by	by	ADP
fnp-5848	133	30	modulating	modulate	VERB
fnp-5848	133	31	the	the	DET
fnp-5848	133	32	immune	immune	ADJ
fnp-5848	133	33	response	response	NOUN
fnp-5848	133	34	.	.	PUNCT
fnp-5848	134	1	8	8	X
fnp-5848	134	2	.	.	X
fnp-5848	134	3	 	 	SPACE
fnp-5848	134	4	viral	viral	ADJ
fnp-5848	134	5	exposures	exposure	NOUN
fnp-5848	134	6	linked	link	VERB
fnp-5848	134	7	to	to	ADP
fnp-5848	134	8	neurodegeneration	neurodegeneration	NOUN
fnp-5848	134	9	growing	grow	VERB
fnp-5848	134	10	evidence	evidence	NOUN
fnp-5848	134	11	has	have	AUX
fnp-5848	134	12	increasingly	increasingly	ADV
fnp-5848	134	13	spotlighted	spotlight	VERB
fnp-5848	134	14	the	the	DET
fnp-5848	134	15	potential	potential	ADJ
fnp-5848	134	16	causal	causal	ADJ
fnp-5848	134	17	role	role	NOUN
fnp-5848	134	18	of	of	ADP
fnp-5848	134	19	viruses	virus	NOUN
fnp-5848	134	20	in	in	ADP
fnp-5848	134	21	neurodegenerative	neurodegenerative	ADJ
fnp-5848	134	22	diseases	disease	NOUN
fnp-5848	134	23	(	(	PUNCT
fnp-5848	134	24	ndds	ndds	PROPN
fnp-5848	134	25	)	)	PUNCT
fnp-5848	134	26	.	.	PUNCT
fnp-5848	135	1	historical	historical	ADJ
fnp-5848	135	2	examples	example	NOUN
fnp-5848	135	3	,	,	PUNCT
fnp-5848	135	4	such	such	ADJ
fnp-5848	135	5	as	as	ADP
fnp-5848	135	6	post	post	ADJ
fnp-5848	135	7	-	-	ADJ
fnp-5848	135	8	encephalitic	encephalitic	ADJ
fnp-5848	135	9	parkinsonism	parkinsonism	NOUN
fnp-5848	135	10	,	,	PUNCT
fnp-5848	135	11	first	first	ADV
fnp-5848	135	12	hinted	hint	VERB
fnp-5848	135	13	at	at	ADP
fnp-5848	135	14	this	this	DET
fnp-5848	135	15	link	link	NOUN
fnp-5848	135	16	,	,	PUNCT
fnp-5848	135	17	and	and	CCONJ
fnp-5848	135	18	subsequent	subsequent	ADJ
fnp-5848	135	19	research	research	NOUN
fnp-5848	135	20	has	have	AUX
fnp-5848	135	21	suggested	suggest	VERB
fnp-5848	135	22	associations	association	NOUN
fnp-5848	135	23	with	with	ADP
fnp-5848	135	24	viruses	virus	NOUN
fnp-5848	135	25	like	like	ADP
fnp-5848	135	26	herpes	herpe	NOUN
fnp-5848	135	27	simplex	simplex	NOUN
fnp-5848	135	28	virus	virus	NOUN
fnp-5848	135	29	(	(	PUNCT
fnp-5848	135	30	hsv	hsv	PROPN
fnp-5848	135	31	)	)	PUNCT
fnp-5848	135	32	.	.	PUNCT
fnp-5848	136	1	the	the	PRON
fnp-5848	136	2	covid-19	covid-19	PROPN
fnp-5848	136	3	pandemic	pandemic	NOUN
fnp-5848	136	4	further	far	ADV
fnp-5848	136	5	intensified	intensify	VERB
fnp-5848	136	6	speculation	speculation	NOUN
fnp-5848	136	7	regarding	regard	VERB
fnp-5848	136	8	viral	viral	ADJ
fnp-5848	136	9	contributions	contribution	NOUN
fnp-5848	136	10	to	to	ADP
fnp-5848	136	11	neurodegeneration	neurodegeneration	NOUN
fnp-5848	136	12	.	.	PUNCT
fnp-5848	137	1	most	most	ADV
fnp-5848	137	2	notably	notably	ADV
fnp-5848	137	3	,	,	PUNCT
fnp-5848	137	4	recent	recent	ADJ
fnp-5848	137	5	studies	study	NOUN
fnp-5848	137	6	have	have	AUX
fnp-5848	137	7	strongly	strongly	ADV
fnp-5848	137	8	linked	link	VERB
fnp-5848	137	9	epstein	epstein	PROPN
fnp-5848	137	10	-	-	PUNCT
fnp-5848	137	11	barr	barr	PROPN
fnp-5848	137	12	virus	virus	PROPN
fnp-5848	137	13	(	(	PUNCT
fnp-5848	137	14	ebv	ebv	NOUN
fnp-5848	137	15	)	)	PUNCT
fnp-5848	137	16	to	to	ADP
fnp-5848	137	17	multiple	multiple	ADJ
fnp-5848	137	18	sclerosis	sclerosis	NOUN
fnp-5848	137	19	(	(	PUNCT
fnp-5848	137	20	ms	ms	NOUN
fnp-5848	137	21	)	)	PUNCT
fnp-5848	137	22	.	.	PUNCT
fnp-5848	138	1	this	this	DET
fnp-5848	138	2	connection	connection	NOUN
fnp-5848	138	3	is	be	AUX
fnp-5848	138	4	significant	significant	ADJ
fnp-5848	138	5	because	because	SCONJ
fnp-5848	138	6	viral	viral	ADJ
fnp-5848	138	7	infections	infection	NOUN
fnp-5848	138	8	can	can	AUX
fnp-5848	138	9	be	be	AUX
fnp-5848	138	10	mitigated	mitigate	VERB
fnp-5848	138	11	through	through	ADP
fnp-5848	138	12	vaccination	vaccination	NOUN
fnp-5848	138	13	or	or	CCONJ
fnp-5848	138	14	treated	treat	VERB
fnp-5848	138	15	with	with	ADP
fnp-5848	138	16	antivirals	antiviral	NOUN
fnp-5848	138	17	,	,	PUNCT
fnp-5848	138	18	presenting	present	VERB
fnp-5848	138	19	vast	vast	ADJ
fnp-5848	138	20	new	new	ADJ
fnp-5848	138	21	possibilities	possibility	NOUN
fnp-5848	138	22	for	for	ADP
fnp-5848	138	23	preventing	prevent	VERB
fnp-5848	138	24	or	or	CCONJ
fnp-5848	138	25	slowing	slow	VERB
fnp-5848	138	26	neurodegenerative	neurodegenerative	ADJ
fnp-5848	138	27	processes	process	NOUN
fnp-5848	138	28	.	.	PUNCT
fnp-5848	139	1	however	however	ADV
fnp-5848	139	2	,	,	PUNCT
fnp-5848	139	3	the	the	DET
fnp-5848	139	4	specific	specific	ADJ
fnp-5848	139	5	mechanisms	mechanism	NOUN
fnp-5848	139	6	by	by	ADP
fnp-5848	139	7	which	which	PRON
fnp-5848	139	8	viral	viral	ADJ
fnp-5848	139	9	exposures	exposure	NOUN
fnp-5848	139	10	contribute	contribute	VERB
fnp-5848	139	11	to	to	ADP
fnp-5848	139	12	ndds	ndd	NOUN
fnp-5848	139	13	remain	remain	VERB
fnp-5848	139	14	unclear	unclear	ADJ
fnp-5848	139	15	,	,	PUNCT
fnp-5848	139	16	representing	represent	VERB
fnp-5848	139	17	a	a	DET
fnp-5848	139	18	critical	critical	ADJ
fnp-5848	139	19	gap	gap	NOUN
fnp-5848	139	20	in	in	ADP
fnp-5848	139	21	our	our	PRON
fnp-5848	139	22	understanding	understanding	NOUN
fnp-5848	139	23	and	and	CCONJ
fnp-5848	139	24	a	a	DET
fnp-5848	139	25	barrier	barrier	NOUN
fnp-5848	139	26	to	to	ADP
fnp-5848	139	27	developing	develop	VERB
fnp-5848	139	28	targeted	target	VERB
fnp-5848	139	29	interventions	intervention	NOUN
fnp-5848	139	30	.	.	PUNCT
fnp-5848	140	1	a	a	DET
fnp-5848	140	2	study	study	NOUN
fnp-5848	140	3	published	publish	VERB
fnp-5848	140	4	in	in	ADP
fnp-5848	140	5	neuron	neuron	NOUN
fnp-5848	140	6	by	by	ADP
fnp-5848	140	7	levine	levine	PROPN
fnp-5848	140	8	et	et	PROPN
fnp-5848	140	9	al	al	PROPN
fnp-5848	140	10	.	.	PROPN
fnp-5848	140	11	examines	examine	VERB
fnp-5848	140	12	the	the	DET
fnp-5848	140	13	association	association	NOUN
fnp-5848	140	14	between	between	ADP
fnp-5848	140	15	viral	viral	ADJ
fnp-5848	140	16	exposures	exposure	NOUN
fnp-5848	140	17	https://doi.org/10.17879/freeneuropathology-2024free	https://doi.org/10.17879/freeneuropathology-2024free	PROPN
fnp-5848	140	18	neuropathology	neuropathology	NOUN
fnp-5848	140	19	5:31	5:31	NUM
fnp-5848	140	20	(	(	PUNCT
fnp-5848	140	21	2024	2024	NUM
fnp-5848	140	22	)	)	PUNCT
fnp-5848	140	23	john	john	PROPN
fnp-5848	140	24	f.	f.	PROPN
fnp-5848	140	25	crary	crary	PROPN
fnp-5848	140	26	doi	doi	PROPN
fnp-5848	140	27	:	:	PUNCT
fnp-5848	140	28	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	140	29	page	page	NOUN
fnp-5848	140	30	9	9	NUM
fnp-5848	140	31	of	of	ADP
fnp-5848	140	32	12	12	NUM
fnp-5848	140	33	and	and	CCONJ
fnp-5848	140	34	the	the	DET
fnp-5848	140	35	risk	risk	NOUN
fnp-5848	140	36	of	of	ADP
fnp-5848	140	37	developing	develop	VERB
fnp-5848	140	38	neurodegenerative	neurodegenerative	ADJ
fnp-5848	140	39	diseases	disease	NOUN
fnp-5848	140	40	(	(	PUNCT
fnp-5848	140	41	ndds	ndds	X
fnp-5848	140	42	)	)	PUNCT
fnp-5848	140	43	using	use	VERB
fnp-5848	140	44	large	large	ADJ
fnp-5848	140	45	-	-	PUNCT
fnp-5848	140	46	scale	scale	NOUN
fnp-5848	140	47	biobank	biobank	ADJ
fnp-5848	140	48	data	datum	NOUN
fnp-5848	140	49	from	from	ADP
fnp-5848	140	50	finngen	finngen	NOUN
fnp-5848	140	51	and	and	CCONJ
fnp-5848	140	52	the	the	DET
fnp-5848	140	53	uk	uk	PROPN
fnp-5848	140	54	biobank	biobank	PROPN
fnp-5848	140	55	(	(	PUNCT
fnp-5848	140	56	levine	levine	PROPN
fnp-5848	140	57	et	et	PROPN
fnp-5848	140	58	al	al	PROPN
fnp-5848	140	59	.	.	PROPN
fnp-5848	140	60	,	,	PUNCT
fnp-5848	140	61	2023	2023	NUM
fnp-5848	140	62	)	)	PUNCT
fnp-5848	140	63	.	.	PUNCT
fnp-5848	141	1	the	the	DET
fnp-5848	141	2	researchers	researcher	NOUN
fnp-5848	141	3	identified	identify	VERB
fnp-5848	141	4	45	45	NUM
fnp-5848	141	5	significant	significant	ADJ
fnp-5848	141	6	viral	viral	ADJ
fnp-5848	141	7	-	-	PUNCT
fnp-5848	141	8	ndd	ndd	NOUN
fnp-5848	141	9	associations	association	NOUN
fnp-5848	141	10	in	in	ADP
fnp-5848	141	11	the	the	DET
fnp-5848	141	12	discovery	discovery	NOUN
fnp-5848	141	13	phase	phase	NOUN
fnp-5848	141	14	with	with	ADP
fnp-5848	141	15	finngen	finngen	NOUN
fnp-5848	141	16	,	,	PUNCT
fnp-5848	141	17	and	and	CCONJ
fnp-5848	141	18	successfully	successfully	ADV
fnp-5848	141	19	replicated	replicate	VERB
fnp-5848	141	20	22	22	NUM
fnp-5848	141	21	of	of	ADP
fnp-5848	141	22	these	these	DET
fnp-5848	141	23	associations	association	NOUN
fnp-5848	141	24	in	in	ADP
fnp-5848	141	25	the	the	DET
fnp-5848	141	26	replication	replication	NOUN
fnp-5848	141	27	phase	phase	NOUN
fnp-5848	141	28	using	use	VERB
fnp-5848	141	29	the	the	DET
fnp-5848	141	30	uk	uk	PROPN
fnp-5848	141	31	biobank	biobank	NOUN
fnp-5848	141	32	.	.	PUNCT
fnp-5848	142	1	notably	notably	ADV
fnp-5848	142	2	,	,	PUNCT
fnp-5848	142	3	the	the	DET
fnp-5848	142	4	strongest	strong	ADJ
fnp-5848	142	5	association	association	NOUN
fnp-5848	142	6	was	be	AUX
fnp-5848	142	7	observed	observe	VERB
fnp-5848	142	8	between	between	ADP
fnp-5848	142	9	viral	viral	ADJ
fnp-5848	142	10	encephalitis	encephalitis	NOUN
fnp-5848	142	11	(	(	PUNCT
fnp-5848	142	12	not	not	PART
fnp-5848	142	13	elsewhere	elsewhere	ADV
fnp-5848	142	14	classified	classified	ADJ
fnp-5848	142	15	/	/	SYM
fnp-5848	142	16	unspecified	unspecified	ADJ
fnp-5848	142	17	)	)	PUNCT
fnp-5848	142	18	and	and	CCONJ
fnp-5848	142	19	alzheimer	alzheimer	PROPN
fnp-5848	142	20	’s	’s	PART
fnp-5848	142	21	disease	disease	NOUN
fnp-5848	142	22	(	(	PUNCT
fnp-5848	142	23	ad	ad	NOUN
fnp-5848	142	24	)	)	PUNCT
fnp-5848	142	25	,	,	PUNCT
fnp-5848	142	26	with	with	ADP
fnp-5848	142	27	a	a	DET
fnp-5848	142	28	hazard	hazard	NOUN
fnp-5848	142	29	ratio	ratio	NOUN
fnp-5848	142	30	of	of	ADP
fnp-5848	142	31	30.72	30.72	NUM
fnp-5848	142	32	in	in	ADP
fnp-5848	142	33	finngen	finngen	NOUN
fnp-5848	142	34	and	and	CCONJ
fnp-5848	142	35	an	an	DET
fnp-5848	142	36	odds	odd	NOUN
fnp-5848	142	37	ratio	ratio	NOUN
fnp-5848	142	38	of	of	ADP
fnp-5848	142	39	22.06	22.06	NUM
fnp-5848	142	40	in	in	ADP
fnp-5848	142	41	the	the	DET
fnp-5848	142	42	uk	uk	PROPN
fnp-5848	142	43	biobank	biobank	NOUN
fnp-5848	142	44	.	.	PUNCT
fnp-5848	143	1	other	other	ADJ
fnp-5848	143	2	significant	significant	ADJ
fnp-5848	143	3	associations	association	NOUN
fnp-5848	143	4	included	include	VERB
fnp-5848	143	5	influenza	influenza	NOUN
fnp-5848	143	6	with	with	ADP
fnp-5848	143	7	pneumonia	pneumonia	NOUN
fnp-5848	143	8	,	,	PUNCT
fnp-5848	143	9	which	which	PRON
fnp-5848	143	10	was	be	AUX
fnp-5848	143	11	linked	link	VERB
fnp-5848	143	12	to	to	ADP
fnp-5848	143	13	an	an	DET
fnp-5848	143	14	increased	increase	VERB
fnp-5848	143	15	risk	risk	NOUN
fnp-5848	143	16	of	of	ADP
fnp-5848	143	17	five	five	NUM
fnp-5848	143	18	of	of	ADP
fnp-5848	143	19	the	the	DET
fnp-5848	143	20	six	six	NUM
fnp-5848	143	21	studied	studied	ADJ
fnp-5848	143	22	ndds	ndd	NOUN
fnp-5848	143	23	,	,	PUNCT
fnp-5848	143	24	including	include	VERB
fnp-5848	143	25	ad	ad	NOUN
fnp-5848	143	26	,	,	PUNCT
fnp-5848	143	27	amyotrophic	amyotrophic	ADJ
fnp-5848	143	28	lateral	lateral	ADJ
fnp-5848	143	29	sclerosis	sclerosis	NOUN
fnp-5848	143	30	(	(	PUNCT
fnp-5848	143	31	als	als	NOUN
fnp-5848	143	32	)	)	PUNCT
fnp-5848	143	33	,	,	PUNCT
fnp-5848	143	34	dementia	dementia	NOUN
fnp-5848	143	35	,	,	PUNCT
fnp-5848	143	36	parkinson	parkinson	NOUN
fnp-5848	143	37	's	's	PART
fnp-5848	143	38	disease	disease	NOUN
fnp-5848	143	39	(	(	PUNCT
fnp-5848	143	40	pd	pd	NOUN
fnp-5848	143	41	)	)	PUNCT
fnp-5848	143	42	,	,	PUNCT
fnp-5848	143	43	and	and	CCONJ
fnp-5848	143	44	vascular	vascular	ADJ
fnp-5848	143	45	dementia	dementia	NOUN
fnp-5848	143	46	(	(	PUNCT
fnp-5848	143	47	vas	vas	NOUN
fnp-5848	143	48	)	)	PUNCT
fnp-5848	143	49	.	.	PUNCT
fnp-5848	144	1	the	the	DET
fnp-5848	144	2	analysis	analysis	NOUN
fnp-5848	144	3	highlighted	highlight	VERB
fnp-5848	144	4	the	the	DET
fnp-5848	144	5	long	long	ADJ
fnp-5848	144	6	-	-	PUNCT
fnp-5848	144	7	term	term	NOUN
fnp-5848	144	8	impact	impact	NOUN
fnp-5848	144	9	of	of	ADP
fnp-5848	144	10	viral	viral	ADJ
fnp-5848	144	11	exposures	exposure	NOUN
fnp-5848	144	12	,	,	PUNCT
fnp-5848	144	13	showing	show	VERB
fnp-5848	144	14	that	that	SCONJ
fnp-5848	144	15	some	some	DET
fnp-5848	144	16	associations	association	NOUN
fnp-5848	144	17	persisted	persist	VERB
fnp-5848	144	18	up	up	ADP
fnp-5848	144	19	to	to	PART
fnp-5848	144	20	15	15	NUM
fnp-5848	144	21	years	year	NOUN
fnp-5848	144	22	prior	prior	ADV
fnp-5848	144	23	to	to	ADP
fnp-5848	144	24	ndd	ndd	NOUN
fnp-5848	144	25	diagnosis	diagnosis	NOUN
fnp-5848	144	26	.	.	PUNCT
fnp-5848	145	1	the	the	DET
fnp-5848	145	2	study	study	NOUN
fnp-5848	145	3	also	also	ADV
fnp-5848	145	4	replicated	replicate	VERB
fnp-5848	145	5	the	the	DET
fnp-5848	145	6	association	association	NOUN
fnp-5848	145	7	between	between	ADP
fnp-5848	145	8	epstein	epstein	PROPN
fnp-5848	145	9	-	-	PUNCT
fnp-5848	145	10	barr	barr	PROPN
fnp-5848	145	11	virus	virus	PROPN
fnp-5848	145	12	(	(	PUNCT
fnp-5848	145	13	ebv	ebv	NOUN
fnp-5848	145	14	)	)	PUNCT
fnp-5848	145	15	and	and	CCONJ
fnp-5848	145	16	multiple	multiple	ADJ
fnp-5848	145	17	sclerosis	sclerosis	NOUN
fnp-5848	145	18	(	(	PUNCT
fnp-5848	145	19	ms	ms	NOUN
fnp-5848	145	20	)	)	PUNCT
fnp-5848	145	21	.	.	PUNCT
fnp-5848	146	1	importantly	importantly	ADV
fnp-5848	146	2	,	,	PUNCT
fnp-5848	146	3	the	the	DET
fnp-5848	146	4	findings	finding	NOUN
fnp-5848	146	5	suggest	suggest	VERB
fnp-5848	146	6	that	that	SCONJ
fnp-5848	146	7	vaccination	vaccination	NOUN
fnp-5848	146	8	against	against	ADP
fnp-5848	146	9	certain	certain	ADJ
fnp-5848	146	10	viruses	virus	NOUN
fnp-5848	146	11	,	,	PUNCT
fnp-5848	146	12	such	such	ADJ
fnp-5848	146	13	as	as	ADP
fnp-5848	146	14	influenza	influenza	NOUN
fnp-5848	146	15	and	and	CCONJ
fnp-5848	146	16	varicella	varicella	NOUN
fnp-5848	146	17	-	-	NOUN
fnp-5848	146	18	zoster	zoster	NOUN
fnp-5848	146	19	,	,	PUNCT
fnp-5848	146	20	might	might	AUX
fnp-5848	146	21	reduce	reduce	VERB
fnp-5848	146	22	the	the	DET
fnp-5848	146	23	risk	risk	NOUN
fnp-5848	146	24	of	of	ADP
fnp-5848	146	25	developing	develop	VERB
fnp-5848	146	26	ndds	ndd	NOUN
fnp-5848	146	27	.	.	PUNCT
fnp-5848	147	1	it	it	PRON
fnp-5848	147	2	is	be	AUX
fnp-5848	147	3	important	important	ADJ
fnp-5848	147	4	to	to	PART
fnp-5848	147	5	note	note	VERB
fnp-5848	147	6	that	that	SCONJ
fnp-5848	147	7	the	the	DET
fnp-5848	147	8	reverse	reverse	ADJ
fnp-5848	147	9	causality	causality	NOUN
fnp-5848	147	10	has	have	AUX
fnp-5848	147	11	not	not	PART
fnp-5848	147	12	been	be	AUX
fnp-5848	147	13	eliminated	eliminate	VERB
fnp-5848	147	14	.	.	PUNCT
fnp-5848	148	1	the	the	DET
fnp-5848	148	2	possibility	possibility	NOUN
fnp-5848	148	3	that	that	SCONJ
fnp-5848	148	4	patients	patient	NOUN
fnp-5848	148	5	in	in	ADP
fnp-5848	148	6	the	the	DET
fnp-5848	148	7	presymptomatic	presymptomatic	ADJ
fnp-5848	148	8	phases	phase	NOUN
fnp-5848	148	9	of	of	ADP
fnp-5848	148	10	neurodegenerative	neurodegenerative	ADJ
fnp-5848	148	11	disease	disease	NOUN
fnp-5848	148	12	might	might	AUX
fnp-5848	148	13	be	be	AUX
fnp-5848	148	14	at	at	ADP
fnp-5848	148	15	risk	risk	NOUN
fnp-5848	148	16	for	for	ADP
fnp-5848	148	17	viral	viral	ADJ
fnp-5848	148	18	infection	infection	NOUN
fnp-5848	148	19	needs	need	VERB
fnp-5848	148	20	to	to	PART
fnp-5848	148	21	be	be	AUX
fnp-5848	148	22	addressed	address	VERB
fnp-5848	148	23	more	more	ADV
fnp-5848	148	24	closely	closely	ADV
fnp-5848	148	25	.	.	PUNCT
fnp-5848	149	1	the	the	DET
fnp-5848	149	2	study	study	NOUN
fnp-5848	149	3	emphasizes	emphasize	VERB
fnp-5848	149	4	the	the	DET
fnp-5848	149	5	need	need	NOUN
fnp-5848	149	6	for	for	ADP
fnp-5848	149	7	more	more	ADJ
fnp-5848	149	8	research	research	NOUN
fnp-5848	149	9	into	into	ADP
fnp-5848	149	10	the	the	DET
fnp-5848	149	11	role	role	NOUN
fnp-5848	149	12	of	of	ADP
fnp-5848	149	13	viral	viral	ADJ
fnp-5848	149	14	infections	infection	NOUN
fnp-5848	149	15	in	in	ADP
fnp-5848	149	16	the	the	DET
fnp-5848	149	17	pathogenesis	pathogenesis	NOUN
fnp-5848	149	18	of	of	ADP
fnp-5848	149	19	neurodegenerative	neurodegenerative	ADJ
fnp-5848	149	20	diseases	disease	NOUN
fnp-5848	149	21	and	and	CCONJ
fnp-5848	149	22	suggests	suggest	VERB
fnp-5848	149	23	that	that	SCONJ
fnp-5848	149	24	leveraging	leverage	VERB
fnp-5848	149	25	vaccination	vaccination	NOUN
fnp-5848	149	26	and	and	CCONJ
fnp-5848	149	27	antiviral	antiviral	ADJ
fnp-5848	149	28	strategies	strategy	NOUN
fnp-5848	149	29	might	might	AUX
fnp-5848	149	30	offer	offer	VERB
fnp-5848	149	31	new	new	ADJ
fnp-5848	149	32	avenues	avenue	NOUN
fnp-5848	149	33	for	for	ADP
fnp-5848	149	34	prevention	prevention	NOUN
fnp-5848	149	35	and	and	CCONJ
fnp-5848	149	36	treatment	treatment	NOUN
fnp-5848	149	37	.	.	PUNCT
fnp-5848	150	1	these	these	DET
fnp-5848	150	2	findings	finding	NOUN
fnp-5848	150	3	underscore	underscore	VERB
fnp-5848	150	4	the	the	DET
fnp-5848	150	5	importance	importance	NOUN
fnp-5848	150	6	of	of	ADP
fnp-5848	150	7	considering	consider	VERB
fnp-5848	150	8	viral	viral	ADJ
fnp-5848	150	9	exposure	exposure	NOUN
fnp-5848	150	10	history	history	NOUN
fnp-5848	150	11	in	in	ADP
fnp-5848	150	12	ndd	ndd	PROPN
fnp-5848	150	13	risk	risk	NOUN
fnp-5848	150	14	assessments	assessment	NOUN
fnp-5848	150	15	and	and	CCONJ
fnp-5848	150	16	highlight	highlight	VERB
fnp-5848	150	17	the	the	DET
fnp-5848	150	18	potential	potential	NOUN
fnp-5848	150	19	for	for	ADP
fnp-5848	150	20	public	public	ADJ
fnp-5848	150	21	health	health	NOUN
fnp-5848	150	22	interventions	intervention	NOUN
fnp-5848	150	23	to	to	PART
fnp-5848	150	24	mitigate	mitigate	VERB
fnp-5848	150	25	these	these	DET
fnp-5848	150	26	risks	risk	NOUN
fnp-5848	150	27	.	.	PUNCT
fnp-5848	151	1	9	9	X
fnp-5848	151	2	.	.	X
fnp-5848	151	3	 	 	SPACE
fnp-5848	151	4	polyglutamine	polyglutamine	NOUN
fnp-5848	151	5	(	(	PUNCT
fnp-5848	151	6	polyq	polyq	NOUN
fnp-5848	151	7	)	)	PUNCT
fnp-5848	151	8	diseases	disease	NOUN
fnp-5848	151	9	:	:	PUNCT
fnp-5848	151	10	ribosomal	ribosomal	NOUN
fnp-5848	151	11	proteins	protein	NOUN
fnp-5848	151	12	and	and	CCONJ
fnp-5848	151	13	tauopathy	tauopathy	ADJ
fnp-5848	151	14	polyglutamine	polyglutamine	NOUN
fnp-5848	151	15	(	(	PUNCT
fnp-5848	151	16	polyq	polyq	NOUN
fnp-5848	151	17	)	)	PUNCT
fnp-5848	151	18	diseases	disease	NOUN
fnp-5848	151	19	,	,	PUNCT
fnp-5848	151	20	such	such	ADJ
fnp-5848	151	21	as	as	ADP
fnp-5848	151	22	huntington	huntington	PROPN
fnp-5848	151	23	's	's	PART
fnp-5848	151	24	disease	disease	NOUN
fnp-5848	151	25	(	(	PUNCT
fnp-5848	151	26	hd	hd	NOUN
fnp-5848	151	27	)	)	PUNCT
fnp-5848	151	28	and	and	CCONJ
fnp-5848	151	29	various	various	ADJ
fnp-5848	151	30	spinocerebellar	spinocerebellar	ADJ
fnp-5848	151	31	ataxias	ataxia	NOUN
fnp-5848	151	32	,	,	PUNCT
fnp-5848	151	33	represent	represent	VERB
fnp-5848	151	34	an	an	DET
fnp-5848	151	35	important	important	ADJ
fnp-5848	151	36	yet	yet	ADV
fnp-5848	151	37	understudied	understudied	ADJ
fnp-5848	151	38	group	group	NOUN
fnp-5848	151	39	of	of	ADP
fnp-5848	151	40	neurodegenerative	neurodegenerative	ADJ
fnp-5848	151	41	disorders	disorder	NOUN
fnp-5848	151	42	.	.	PUNCT
fnp-5848	152	1	these	these	DET
fnp-5848	152	2	diseases	disease	NOUN
fnp-5848	152	3	are	be	AUX
fnp-5848	152	4	caused	cause	VERB
fnp-5848	152	5	by	by	ADP
fnp-5848	152	6	cag	cag	PROPN
fnp-5848	152	7	-	-	PUNCT
fnp-5848	152	8	repeat	repeat	NOUN
fnp-5848	152	9	expansions	expansion	NOUN
fnp-5848	152	10	in	in	ADP
fnp-5848	152	11	different	different	ADJ
fnp-5848	152	12	genes	gene	NOUN
fnp-5848	152	13	and	and	CCONJ
fnp-5848	152	14	are	be	AUX
fnp-5848	152	15	characterized	characterize	VERB
fnp-5848	152	16	by	by	ADP
fnp-5848	152	17	neuronal	neuronal	ADJ
fnp-5848	152	18	intranuclear	intranuclear	NOUN
fnp-5848	152	19	inclusions	inclusion	NOUN
fnp-5848	152	20	(	(	PUNCT
fnp-5848	152	21	niis	niis	NOUN
fnp-5848	152	22	)	)	PUNCT
fnp-5848	152	23	,	,	PUNCT
fnp-5848	152	24	which	which	PRON
fnp-5848	152	25	play	play	VERB
fnp-5848	152	26	a	a	DET
fnp-5848	152	27	key	key	ADJ
fnp-5848	152	28	role	role	NOUN
fnp-5848	152	29	in	in	ADP
fnp-5848	152	30	disease	disease	NOUN
fnp-5848	152	31	pathology	pathology	NOUN
fnp-5848	152	32	.	.	PUNCT
fnp-5848	153	1	niis	niis	PROPN
fnp-5848	153	2	are	be	AUX
fnp-5848	153	3	not	not	PART
fnp-5848	153	4	only	only	ADV
fnp-5848	153	5	central	central	ADJ
fnp-5848	153	6	to	to	ADP
fnp-5848	153	7	polyq	polyq	NOUN
fnp-5848	153	8	disorders	disorder	NOUN
fnp-5848	153	9	but	but	CCONJ
fnp-5848	153	10	are	be	AUX
fnp-5848	153	11	also	also	ADV
fnp-5848	153	12	observed	observe	VERB
fnp-5848	153	13	in	in	ADP
fnp-5848	153	14	normal	normal	ADJ
fnp-5848	153	15	aging	aging	NOUN
fnp-5848	153	16	,	,	PUNCT
fnp-5848	153	17	as	as	SCONJ
fnp-5848	153	18	evidenced	evidence	VERB
fnp-5848	153	19	by	by	ADP
fnp-5848	153	20	marinesco	marinesco	ADJ
fnp-5848	153	21	bodies	body	NOUN
fnp-5848	153	22	in	in	ADP
fnp-5848	153	23	the	the	DET
fnp-5848	153	24	substantia	substantia	NOUN
fnp-5848	153	25	nigra	nigra	NOUN
fnp-5848	153	26	and	and	CCONJ
fnp-5848	153	27	locus	locus	NOUN
fnp-5848	153	28	coeruleus	coeruleus	NOUN
fnp-5848	153	29	.	.	PUNCT
fnp-5848	154	1	however	however	ADV
fnp-5848	154	2	,	,	PUNCT
fnp-5848	154	3	the	the	DET
fnp-5848	154	4	formation	formation	NOUN
fnp-5848	154	5	of	of	ADP
fnp-5848	154	6	niis	niis	NOUN
fnp-5848	154	7	and	and	CCONJ
fnp-5848	154	8	their	their	PRON
fnp-5848	154	9	precise	precise	ADJ
fnp-5848	154	10	role	role	NOUN
fnp-5848	154	11	in	in	ADP
fnp-5848	154	12	neurodegeneration	neurodegeneration	NOUN
fnp-5848	154	13	remain	remain	AUX
fnp-5848	154	14	poorly	poorly	ADV
fnp-5848	154	15	understood	understand	VERB
fnp-5848	154	16	,	,	PUNCT
fnp-5848	154	17	representing	represent	VERB
fnp-5848	154	18	a	a	DET
fnp-5848	154	19	critical	critical	ADJ
fnp-5848	154	20	gap	gap	NOUN
fnp-5848	154	21	in	in	ADP
fnp-5848	154	22	knowledge	knowledge	NOUN
fnp-5848	154	23	.	.	PUNCT
fnp-5848	155	1	addressing	address	VERB
fnp-5848	155	2	this	this	DET
fnp-5848	155	3	gap	gap	NOUN
fnp-5848	155	4	through	through	ADP
fnp-5848	155	5	focused	focused	ADJ
fnp-5848	155	6	research	research	NOUN
fnp-5848	155	7	on	on	ADP
fnp-5848	155	8	polyq	polyq	NOUN
fnp-5848	155	9	disorders	disorder	NOUN
fnp-5848	155	10	and	and	CCONJ
fnp-5848	155	11	related	related	ADJ
fnp-5848	155	12	inclusions	inclusion	NOUN
fnp-5848	155	13	is	be	AUX
fnp-5848	155	14	essential	essential	ADJ
fnp-5848	155	15	for	for	ADP
fnp-5848	155	16	advancing	advance	VERB
fnp-5848	155	17	our	our	PRON
fnp-5848	155	18	understanding	understanding	NOUN
fnp-5848	155	19	of	of	ADP
fnp-5848	155	20	these	these	DET
fnp-5848	155	21	complex	complex	ADJ
fnp-5848	155	22	diseases	disease	NOUN
fnp-5848	155	23	and	and	CCONJ
fnp-5848	155	24	their	their	PRON
fnp-5848	155	25	broader	broad	ADJ
fnp-5848	155	26	implications	implication	NOUN
fnp-5848	155	27	for	for	ADP
fnp-5848	155	28	neurodegeneration	neurodegeneration	NOUN
fnp-5848	155	29	.	.	PUNCT
fnp-5848	156	1	few	few	ADJ
fnp-5848	156	2	neuropathological	neuropathological	ADJ
fnp-5848	156	3	studies	study	NOUN
fnp-5848	156	4	focusing	focus	VERB
fnp-5848	156	5	specifically	specifically	ADV
fnp-5848	156	6	on	on	ADP
fnp-5848	156	7	polyq	polyq	NOUN
fnp-5848	156	8	disorders	disorder	NOUN
fnp-5848	156	9	are	be	AUX
fnp-5848	156	10	published	publish	VERB
fnp-5848	156	11	each	each	DET
fnp-5848	156	12	year	year	NOUN
fnp-5848	156	13	,	,	PUNCT
fnp-5848	156	14	but	but	CCONJ
fnp-5848	156	15	two	two	NUM
fnp-5848	156	16	notable	notable	ADJ
fnp-5848	156	17	studies	study	NOUN
fnp-5848	156	18	were	be	AUX
fnp-5848	156	19	recently	recently	ADV
fnp-5848	156	20	conducted	conduct	VERB
fnp-5848	156	21	.	.	PUNCT
fnp-5848	157	1	one	one	NUM
fnp-5848	157	2	study	study	NOUN
fnp-5848	157	3	by	by	ADP
fnp-5848	157	4	yagita	yagita	PROPN
fnp-5848	157	5	et	et	PROPN
fnp-5848	157	6	al	al	PROPN
fnp-5848	157	7	.	.	PROPN
fnp-5848	157	8	published	publish	VERB
fnp-5848	157	9	in	in	ADP
fnp-5848	157	10	neuropathology	neuropathology	NOUN
fnp-5848	157	11	investigated	investigate	VERB
fnp-5848	157	12	the	the	DET
fnp-5848	157	13	ribosomal	ribosomal	NOUN
fnp-5848	157	14	protein	protein	NOUN
fnp-5848	157	15	sa	sa	NOUN
fnp-5848	157	16	(	(	PUNCT
fnp-5848	157	17	rpsa	rpsa	PROPN
fnp-5848	157	18	)	)	PUNCT
fnp-5848	157	19	in	in	ADP
fnp-5848	157	20	neuronal	neuronal	ADJ
fnp-5848	157	21	intranuclear	intranuclear	NOUN
fnp-5848	157	22	inclusions	inclusion	NOUN
fnp-5848	157	23	(	(	PUNCT
fnp-5848	157	24	niis	niis	NOUN
fnp-5848	157	25	)	)	PUNCT
fnp-5848	157	26	associated	associate	VERB
fnp-5848	157	27	with	with	ADP
fnp-5848	157	28	polyglutamine	polyglutamine	NOUN
fnp-5848	157	29	(	(	PUNCT
fnp-5848	157	30	polyq	polyq	NOUN
fnp-5848	157	31	)	)	PUNCT
fnp-5848	157	32	diseases	disease	NOUN
fnp-5848	157	33	and	and	CCONJ
fnp-5848	157	34	marinesco	marinesco	ADJ
fnp-5848	157	35	bodies	body	NOUN
fnp-5848	157	36	(	(	PUNCT
fnp-5848	157	37	mbs	mb	NOUN
fnp-5848	157	38	)	)	PUNCT
fnp-5848	157	39	in	in	ADP
fnp-5848	157	40	normal	normal	ADJ
fnp-5848	157	41	aging	age	VERB
fnp-5848	157	42	brains	brain	NOUN
fnp-5848	157	43	(	(	PUNCT
fnp-5848	157	44	yagita	yagita	X
fnp-5848	157	45	et	et	PROPN
fnp-5848	157	46	al	al	PROPN
fnp-5848	157	47	.	.	PROPN
fnp-5848	157	48	,	,	PUNCT
fnp-5848	157	49	2024	2024	NUM
fnp-5848	157	50	)	)	PUNCT
fnp-5848	157	51	.	.	PUNCT
fnp-5848	158	1	utilizing	utilize	VERB
fnp-5848	158	2	immunohistochemical	immunohistochemical	ADJ
fnp-5848	158	3	and	and	CCONJ
fnp-5848	158	4	biochemical	biochemical	ADJ
fnp-5848	158	5	analyses	analysis	NOUN
fnp-5848	158	6	,	,	PUNCT
fnp-5848	158	7	the	the	DET
fnp-5848	158	8	researchers	researcher	NOUN
fnp-5848	158	9	examined	examine	VERB
fnp-5848	158	10	brain	brain	NOUN
fnp-5848	158	11	samples	sample	NOUN
fnp-5848	158	12	from	from	ADP
fnp-5848	158	13	patients	patient	NOUN
fnp-5848	158	14	with	with	ADP
fnp-5848	158	15	huntington	huntington	PROPN
fnp-5848	158	16	disease	disease	PROPN
fnp-5848	158	17	(	(	PUNCT
fnp-5848	158	18	hd	hd	NOUN
fnp-5848	158	19	)	)	PUNCT
fnp-5848	158	20	,	,	PUNCT
fnp-5848	158	21	spinocerebellar	spinocerebellar	ADJ
fnp-5848	158	22	ataxia	ataxia	NOUN
fnp-5848	158	23	type	type	NOUN
fnp-5848	158	24	3	3	NUM
fnp-5848	158	25	(	(	PUNCT
fnp-5848	158	26	sca3	sca3	PROPN
fnp-5848	158	27	)	)	PUNCT
fnp-5848	158	28	,	,	PUNCT
fnp-5848	158	29	and	and	CCONJ
fnp-5848	158	30	normal	normal	ADJ
fnp-5848	158	31	elderly	elderly	ADJ
fnp-5848	158	32	controls	control	NOUN
fnp-5848	158	33	(	(	PUNCT
fnp-5848	158	34	ncs	ncs	NOUN
fnp-5848	158	35	)	)	PUNCT
fnp-5848	158	36	.	.	PUNCT
fnp-5848	159	1	the	the	DET
fnp-5848	159	2	study	study	NOUN
fnp-5848	159	3	revealed	reveal	VERB
fnp-5848	159	4	that	that	SCONJ
fnp-5848	159	5	rpsa	rpsa	NOUN
fnp-5848	159	6	is	be	AUX
fnp-5848	159	7	a	a	DET
fnp-5848	159	8	common	common	ADJ
fnp-5848	159	9	component	component	NOUN
fnp-5848	159	10	of	of	ADP
fnp-5848	159	11	niis	niis	NOUN
fnp-5848	159	12	in	in	ADP
fnp-5848	159	13	polyq	polyq	NOUN
fnp-5848	159	14	diseases	disease	NOUN
fnp-5848	159	15	and	and	CCONJ
fnp-5848	159	16	mbs	mb	NOUN
fnp-5848	159	17	in	in	ADP
fnp-5848	159	18	normal	normal	ADJ
fnp-5848	159	19	aging	aging	NOUN
fnp-5848	159	20	.	.	PUNCT
fnp-5848	160	1	in	in	ADP
fnp-5848	160	2	polyq	polyq	NOUN
fnp-5848	160	3	diseases	disease	NOUN
fnp-5848	160	4	,	,	PUNCT
fnp-5848	160	5	rpsa	rpsa	ADJ
fnp-5848	160	6	co	co	VERB
fnp-5848	160	7	-	-	VERB
fnp-5848	160	8	localizes	localize	VERB
fnp-5848	160	9	with	with	ADP
fnp-5848	160	10	polyq	polyq	NOUN
fnp-5848	160	11	aggregations	aggregation	NOUN
fnp-5848	160	12	and	and	CCONJ
fnp-5848	160	13	other	other	ADJ
fnp-5848	160	14	proteins	protein	NOUN
fnp-5848	160	15	such	such	ADJ
fnp-5848	160	16	as	as	ADP
fnp-5848	160	17	p62	p62	NOUN
fnp-5848	160	18	,	,	PUNCT
fnp-5848	160	19	ubiquitin	ubiquitin	NOUN
fnp-5848	160	20	,	,	PUNCT
fnp-5848	160	21	and	and	CCONJ
fnp-5848	160	22	huntingtin	huntingtin	NOUN
fnp-5848	160	23	,	,	PUNCT
fnp-5848	160	24	forming	form	VERB
fnp-5848	160	25	a	a	DET
fnp-5848	160	26	mosaic	mosaic	ADJ
fnp-5848	160	27	-	-	PUNCT
fnp-5848	160	28	like	like	ADJ
fnp-5848	160	29	distribution	distribution	NOUN
fnp-5848	160	30	within	within	ADP
fnp-5848	160	31	the	the	DET
fnp-5848	160	32	niis	niis	NOUN
fnp-5848	160	33	.	.	PUNCT
fnp-5848	161	1	the	the	DET
fnp-5848	161	2	nuclear	nuclear	ADJ
fnp-5848	161	3	fraction	fraction	NOUN
fnp-5848	161	4	of	of	ADP
fnp-5848	161	5	hd	hd	NOUN
fnp-5848	161	6	patients	patient	NOUN
fnp-5848	161	7	'	'	PART
fnp-5848	161	8	brain	brain	NOUN
fnp-5848	161	9	samples	sample	NOUN
fnp-5848	161	10	contained	contain	VERB
fnp-5848	161	11	higher	high	ADJ
fnp-5848	161	12	levels	level	NOUN
fnp-5848	161	13	of	of	ADP
fnp-5848	161	14	rpsa	rpsa	NOUN
fnp-5848	161	15	compared	compare	VERB
fnp-5848	161	16	to	to	ADP
fnp-5848	161	17	ncs	ncs	PROPN
fnp-5848	161	18	,	,	PUNCT
fnp-5848	161	19	suggesting	suggest	VERB
fnp-5848	161	20	an	an	DET
fnp-5848	161	21	upregulation	upregulation	NOUN
fnp-5848	161	22	of	of	ADP
fnp-5848	161	23	rpsa	rpsa	NOUN
fnp-5848	161	24	in	in	ADP
fnp-5848	161	25	the	the	DET
fnp-5848	161	26	diseased	diseased	ADJ
fnp-5848	161	27	state	state	NOUN
fnp-5848	161	28	.	.	PUNCT
fnp-5848	162	1	in	in	ADP
fnp-5848	162	2	contrast	contrast	NOUN
fnp-5848	162	3	,	,	PUNCT
fnp-5848	162	4	cytoplasmic	cytoplasmic	ADJ
fnp-5848	162	5	rpsa	rpsa	NOUN
fnp-5848	162	6	expression	expression	NOUN
fnp-5848	162	7	was	be	AUX
fnp-5848	162	8	reduced	reduce	VERB
fnp-5848	162	9	in	in	ADP
fnp-5848	162	10	neurons	neuron	NOUN
fnp-5848	162	11	with	with	ADP
fnp-5848	162	12	niis	niis	NOUN
fnp-5848	162	13	,	,	PUNCT
fnp-5848	162	14	which	which	PRON
fnp-5848	162	15	could	could	AUX
fnp-5848	162	16	imply	imply	VERB
fnp-5848	162	17	sequestration	sequestration	NOUN
fnp-5848	162	18	of	of	ADP
fnp-5848	162	19	rpsa	rpsa	NOUN
fnp-5848	162	20	into	into	ADP
fnp-5848	162	21	the	the	DET
fnp-5848	162	22	inclusions	inclusion	NOUN
fnp-5848	162	23	,	,	PUNCT
fnp-5848	162	24	leading	lead	VERB
fnp-5848	162	25	to	to	ADP
fnp-5848	162	26	its	its	PRON
fnp-5848	162	27	depletion	depletion	NOUN
fnp-5848	162	28	in	in	ADP
fnp-5848	162	29	the	the	DET
fnp-5848	162	30	cytoplasm	cytoplasm	NOUN
fnp-5848	162	31	.	.	PUNCT
fnp-5848	163	1	the	the	DET
fnp-5848	163	2	study	study	NOUN
fnp-5848	163	3	also	also	ADV
fnp-5848	163	4	identified	identify	VERB
fnp-5848	163	5	that	that	SCONJ
fnp-5848	163	6	mbs	mb	NOUN
fnp-5848	163	7	in	in	ADP
fnp-5848	163	8	the	the	DET
fnp-5848	163	9	substantia	substantia	NOUN
fnp-5848	163	10	nigra	nigra	NOUN
fnp-5848	163	11	of	of	ADP
fnp-5848	163	12	ncs	ncs	PROPN
fnp-5848	163	13	share	share	VERB
fnp-5848	163	14	similar	similar	ADJ
fnp-5848	163	15	protein	protein	NOUN
fnp-5848	163	16	components	component	NOUN
fnp-5848	163	17	with	with	ADP
fnp-5848	163	18	niis	niis	NOUN
fnp-5848	163	19	,	,	PUNCT
fnp-5848	163	20	including	include	VERB
fnp-5848	163	21	rpsa	rpsa	NOUN
fnp-5848	163	22	and	and	CCONJ
fnp-5848	163	23	p62	p62	NOUN
fnp-5848	163	24	,	,	PUNCT
fnp-5848	163	25	indicating	indicate	VERB
fnp-5848	163	26	common	common	ADJ
fnp-5848	163	27	mechanisms	mechanism	NOUN
fnp-5848	163	28	may	may	AUX
fnp-5848	163	29	drive	drive	VERB
fnp-5848	163	30	the	the	DET
fnp-5848	163	31	formation	formation	NOUN
fnp-5848	163	32	of	of	ADP
fnp-5848	163	33	these	these	DET
fnp-5848	163	34	intranuclear	intranuclear	NOUN
fnp-5848	163	35	inclusions	inclusion	NOUN
fnp-5848	163	36	.	.	PUNCT
fnp-5848	164	1	these	these	DET
fnp-5848	164	2	findings	finding	NOUN
fnp-5848	164	3	highlight	highlight	VERB
fnp-5848	164	4	the	the	DET
fnp-5848	164	5	role	role	NOUN
fnp-5848	164	6	of	of	ADP
fnp-5848	164	7	ribosomal	ribosomal	ADJ
fnp-5848	164	8	dysfunction	dysfunction	NOUN
fnp-5848	164	9	in	in	ADP
fnp-5848	164	10	both	both	DET
fnp-5848	164	11	neurodegenerative	neurodegenerative	ADJ
fnp-5848	164	12	diseases	disease	NOUN
fnp-5848	164	13	and	and	CCONJ
fnp-5848	164	14	normal	normal	ADJ
fnp-5848	164	15	aging	aging	NOUN
fnp-5848	164	16	,	,	PUNCT
fnp-5848	164	17	providing	provide	VERB
fnp-5848	164	18	new	new	ADJ
fnp-5848	164	19	insights	insight	NOUN
fnp-5848	164	20	into	into	ADP
fnp-5848	164	21	the	the	DET
fnp-5848	164	22	pathogenesis	pathogenesis	NOUN
fnp-5848	164	23	of	of	ADP
fnp-5848	164	24	polyq	polyq	NOUN
fnp-5848	164	25	diseases	disease	NOUN
fnp-5848	164	26	and	and	CCONJ
fnp-5848	164	27	the	the	DET
fnp-5848	164	28	potential	potential	ADJ
fnp-5848	164	29	impact	impact	NOUN
fnp-5848	164	30	of	of	ADP
fnp-5848	164	31	ribosomal	ribosomal	NOUN
fnp-5848	164	32	proteins	protein	NOUN
fnp-5848	164	33	in	in	ADP
fnp-5848	164	34	neuronal	neuronal	ADJ
fnp-5848	164	35	health	health	NOUN
fnp-5848	164	36	and	and	CCONJ
fnp-5848	164	37	disease	disease	NOUN
fnp-5848	164	38	.	.	PUNCT
fnp-5848	165	1	https://doi.org/10.17879/freeneuropathology-2024free	https://doi.org/10.17879/freeneuropathology-2024free	PROPN
fnp-5848	165	2	neuropathology	neuropathology	PROPN
fnp-5848	165	3	5:31	5:31	NUM
fnp-5848	165	4	(	(	PUNCT
fnp-5848	165	5	2024	2024	NUM
fnp-5848	165	6	)	)	PUNCT
fnp-5848	165	7	john	john	PROPN
fnp-5848	165	8	f.	f.	PROPN
fnp-5848	165	9	crary	crary	PROPN
fnp-5848	165	10	doi	doi	PROPN
fnp-5848	165	11	:	:	PUNCT
fnp-5848	165	12	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	165	13	page	page	NOUN
fnp-5848	165	14	10	10	NUM
fnp-5848	165	15	of	of	ADP
fnp-5848	165	16	12	12	NUM
fnp-5848	165	17	figure	figure	NOUN
fnp-5848	165	18	 	 	SPACE
fnp-5848	165	19	5	5	NUM
fnp-5848	165	20	.	.	NOUN
fnp-5848	165	21	tauopathy	tauopathy	NOUN
fnp-5848	165	22	in	in	ADP
fnp-5848	165	23	sca8	sca8	PROPN
fnp-5848	165	24	.	.	PUNCT
fnp-5848	166	1	(	(	PUNCT
fnp-5848	166	2	a	a	X
fnp-5848	166	3	)	)	PUNCT
fnp-5848	166	4	in	in	ADP
fnp-5848	166	5	the	the	DET
fnp-5848	166	6	dentate	dentate	ADJ
fnp-5848	166	7	nucleus	nucleus	NOUN
fnp-5848	166	8	of	of	ADP
fnp-5848	166	9	the	the	DET
fnp-5848	166	10	cerebellum	cerebellum	NOUN
fnp-5848	166	11	,	,	PUNCT
fnp-5848	166	12	grumose	grumose	ADJ
fnp-5848	166	13	degeneration	degeneration	NOUN
fnp-5848	166	14	was	be	AUX
fnp-5848	166	15	observed	observe	VERB
fnp-5848	166	16	.	.	PUNCT
fnp-5848	167	1	(	(	PUNCT
fnp-5848	167	2	b	b	X
fnp-5848	167	3	–	–	PUNCT
fnp-5848	167	4	h	h	NOUN
fnp-5848	167	5	)	)	PUNCT
fnp-5848	167	6	immunohisto	immunohisto	NOUN
fnp-5848	167	7	chemistry	chemistry	NOUN
fnp-5848	167	8	for	for	ADP
fnp-5848	167	9	p	p	PROPN
fnp-5848	167	10	-	-	PUNCT
fnp-5848	167	11	tau	tau	PROPN
fnp-5848	167	12	demonstrateed	demonstrateed	VERB
fnp-5848	167	13	numerous	numerous	ADJ
fnp-5848	167	14	globose	globose	NOUN
fnp-5848	167	15	-	-	PUNCT
fnp-5848	167	16	type	type	NOUN
fnp-5848	167	17	nfts	nft	NOUN
fnp-5848	167	18	,	,	PUNCT
fnp-5848	167	19	threads	thread	NOUN
fnp-5848	167	20	,	,	PUNCT
fnp-5848	167	21	and	and	CCONJ
fnp-5848	167	22	tufted	tufte	VERB
fnp-5848	167	23	astrocytes	astrocyte	NOUN
fnp-5848	167	24	in	in	ADP
fnp-5848	167	25	the	the	DET
fnp-5848	167	26	dentate	dentate	ADJ
fnp-5848	167	27	nucleus	nucleus	NOUN
fnp-5848	167	28	(	(	PUNCT
fnp-5848	167	29	b	b	NOUN
fnp-5848	167	30	)	)	PUNCT
fnp-5848	167	31	,	,	PUNCT
fnp-5848	167	32	internal	internal	ADJ
fnp-5848	167	33	globus	globus	ADJ
fnp-5848	167	34	pallidus	pallidus	NOUN
fnp-5848	167	35	(	(	PUNCT
fnp-5848	167	36	c	c	NOUN
fnp-5848	167	37	)	)	PUNCT
fnp-5848	167	38	,	,	PUNCT
fnp-5848	167	39	subthalamic	subthalamic	ADJ
fnp-5848	167	40	nucleus	nucleus	NOUN
fnp-5848	167	41	(	(	PUNCT
fnp-5848	167	42	d	d	NOUN
fnp-5848	167	43	)	)	PUNCT
fnp-5848	167	44	,	,	PUNCT
fnp-5848	167	45	precentral	precentral	ADJ
fnp-5848	167	46	gyrus	gyrus	NOUN
fnp-5848	167	47	(	(	PUNCT
fnp-5848	167	48	e	e	NOUN
fnp-5848	167	49	,	,	PUNCT
fnp-5848	167	50	f	f	NOUN
fnp-5848	167	51	)	)	PUNCT
fnp-5848	167	52	,	,	PUNCT
fnp-5848	167	53	and	and	CCONJ
fnp-5848	167	54	cerebellum	cerebellum	ADJ
fnp-5848	167	55	(	(	PUNCT
fnp-5848	167	56	g	g	NOUN
fnp-5848	167	57	,	,	PUNCT
fnp-5848	167	58	h	h	NOUN
fnp-5848	167	59	)	)	PUNCT
fnp-5848	167	60	.	.	PUNCT
fnp-5848	168	1	in	in	ADP
fnp-5848	168	2	the	the	DET
fnp-5848	168	3	precentral	precentral	ADJ
fnp-5848	168	4	gyrus	gyrus	NOUN
fnp-5848	168	5	,	,	PUNCT
fnp-5848	168	6	betz	betz	PROPN
fnp-5848	168	7	cells	cell	NOUN
fnp-5848	168	8	were	be	AUX
fnp-5848	168	9	diffusely	diffusely	ADV
fnp-5848	168	10	granular	granular	ADJ
fnp-5848	168	11	positive	positive	ADJ
fnp-5848	168	12	for	for	ADP
fnp-5848	168	13	p	p	PROPN
fnp-5848	168	14	-	-	PUNCT
fnp-5848	168	15	tau	tau	PROPN
fnp-5848	168	16	(	(	PUNCT
fnp-5848	168	17	f	f	PROPN
fnp-5848	168	18	)	)	PUNCT
fnp-5848	168	19	.	.	PUNCT
fnp-5848	169	1	purkinje	purkinje	PROPN
fnp-5848	169	2	cells	cell	NOUN
fnp-5848	169	3	were	be	AUX
fnp-5848	169	4	also	also	ADV
fnp-5848	169	5	positive	positive	ADJ
fnp-5848	169	6	for	for	ADP
fnp-5848	169	7	p	p	PROPN
fnp-5848	169	8	-	-	PUNCT
fnp-5848	169	9	tau	tau	PROPN
fnp-5848	169	10	(	(	PUNCT
fnp-5848	169	11	h	h	NOUN
fnp-5848	169	12	)	)	PUNCT
fnp-5848	169	13	.	.	PUNCT
fnp-5848	170	1	he	he	PRON
fnp-5848	170	2	staining	stain	VERB
fnp-5848	170	3	(	(	PUNCT
fnp-5848	170	4	a	a	X
fnp-5848	170	5	)	)	PUNCT
fnp-5848	170	6	;	;	PUNCT
fnp-5848	170	7	immunohistochemistry	immunohistochemistry	NOUN
fnp-5848	170	8	for	for	ADP
fnp-5848	170	9	p	p	PROPN
fnp-5848	170	10	-	-	PUNCT
fnp-5848	170	11	tau	tau	PROPN
fnp-5848	170	12	(	(	PUNCT
fnp-5848	170	13	b	b	X
fnp-5848	170	14	–	–	PUNCT
fnp-5848	170	15	h	h	NOUN
fnp-5848	170	16	)	)	PUNCT
fnp-5848	170	17	.	.	PUNCT
fnp-5848	171	1	scale	scale	NOUN
fnp-5848	171	2	bars	bar	NOUN
fnp-5848	171	3	:	:	PUNCT
fnp-5848	171	4	100	100	NUM
fnp-5848	171	5	 	 	SPACE
fnp-5848	171	6	μm	μm	INTJ
fnp-5848	171	7	in	in	ADP
fnp-5848	171	8	(	(	PUNCT
fnp-5848	171	9	a	a	DET
fnp-5848	171	10	–	–	PUNCT
fnp-5848	171	11	d	d	NOUN
fnp-5848	171	12	)	)	PUNCT
fnp-5848	171	13	,	,	PUNCT
fnp-5848	171	14	500	500	NUM
fnp-5848	171	15	 	 	SPACE
fnp-5848	171	16	μm	μm	NOUN
fnp-5848	171	17	in	in	ADP
fnp-5848	171	18	(	(	PUNCT
fnp-5848	171	19	e	e	NOUN
fnp-5848	171	20	,	,	PUNCT
fnp-5848	171	21	g	g	NOUN
fnp-5848	171	22	)	)	PUNCT
fnp-5848	171	23	,	,	PUNCT
fnp-5848	171	24	25	25	NUM
fnp-5848	171	25	 	 	SPACE
fnp-5848	171	26	μm	μm	NOUN
fnp-5848	171	27	in	in	ADP
fnp-5848	171	28	(	(	PUNCT
fnp-5848	171	29	f	f	X
fnp-5848	171	30	,	,	PUNCT
fnp-5848	171	31	h	h	NOUN
fnp-5848	171	32	)	)	PUNCT
fnp-5848	171	33	.	.	PUNCT
fnp-5848	172	1	reproduced	reproduce	VERB
fnp-5848	172	2	under	under	ADP
fnp-5848	172	3	the	the	DET
fnp-5848	172	4	creative	creative	ADJ
fnp-5848	172	5	commons	common	NOUN
fnp-5848	172	6	attribution	attribution	NOUN
fnp-5848	172	7	4.0	4.0	NUM
fnp-5848	172	8	international	international	ADJ
fnp-5848	172	9	license	license	NOUN
fnp-5848	172	10	(	(	PUNCT
fnp-5848	172	11	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	172	12	)	)	PUNCT
fnp-5848	172	13	.	.	PUNCT
fnp-5848	173	1	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	https://doi.org/10.17879/freeneuropathology-2024http://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5848	173	2	free	free	ADJ
fnp-5848	173	3	neuropathology	neuropathology	NOUN
fnp-5848	173	4	5:31	5:31	NUM
fnp-5848	173	5	(	(	PUNCT
fnp-5848	173	6	2024	2024	NUM
fnp-5848	173	7	)	)	PUNCT
fnp-5848	173	8	john	john	PROPN
fnp-5848	173	9	f.	f.	PROPN
fnp-5848	173	10	crary	crary	PROPN
fnp-5848	173	11	doi	doi	PROPN
fnp-5848	173	12	:	:	PUNCT
fnp-5848	173	13	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	173	14	page	page	NOUN
fnp-5848	173	15	11	11	NUM
fnp-5848	173	16	of	of	ADP
fnp-5848	173	17	12	12	NUM
fnp-5848	173	18	a	a	DET
fnp-5848	173	19	second	second	ADJ
fnp-5848	173	20	study	study	NOUN
fnp-5848	173	21	also	also	ADV
fnp-5848	173	22	published	publish	VERB
fnp-5848	173	23	in	in	ADP
fnp-5848	173	24	neuropathology	neuropathology	NOUN
fnp-5848	173	25	by	by	ADP
fnp-5848	173	26	yonenobu	yonenobu	PROPN
fnp-5848	173	27	et	et	PROPN
fnp-5848	173	28	al	al	PROPN
fnp-5848	173	29	.	.	PROPN
fnp-5848	173	30	examined	examine	VERB
fnp-5848	173	31	tauopathy	tauopathy	NOUN
fnp-5848	173	32	in	in	ADP
fnp-5848	173	33	spinocerebellar	spinocerebellar	ADJ
fnp-5848	173	34	ataxia	ataxia	NOUN
fnp-5848	173	35	type	type	NOUN
fnp-5848	173	36	8	8	NUM
fnp-5848	173	37	(	(	PUNCT
fnp-5848	173	38	sca8	sca8	PROPN
fnp-5848	173	39	)	)	PUNCT
fnp-5848	173	40	,	,	PUNCT
fnp-5848	173	41	suggesting	suggest	VERB
fnp-5848	173	42	that	that	SCONJ
fnp-5848	173	43	this	this	DET
fnp-5848	173	44	variant	variant	NOUN
fnp-5848	173	45	might	might	AUX
fnp-5848	173	46	display	display	VERB
fnp-5848	173	47	unique	unique	ADJ
fnp-5848	173	48	tauopathic	tauopathic	ADJ
fnp-5848	173	49	features	feature	NOUN
fnp-5848	173	50	(	(	PUNCT
fnp-5848	173	51	yonenobu	yonenobu	NOUN
fnp-5848	173	52	et	et	PROPN
fnp-5848	173	53	al	al	PROPN
fnp-5848	173	54	.	.	PROPN
fnp-5848	173	55	,	,	PUNCT
fnp-5848	173	56	2023	2023	NUM
fnp-5848	173	57	)	)	PUNCT
fnp-5848	173	58	.	.	PUNCT
fnp-5848	174	1	the	the	DET
fnp-5848	174	2	researchers	researcher	NOUN
fnp-5848	174	3	analyzed	analyze	VERB
fnp-5848	174	4	post	post	ADJ
fnp-5848	174	5	-	-	ADJ
fnp-5848	174	6	mortem	mortem	ADJ
fnp-5848	174	7	brain	brain	NOUN
fnp-5848	174	8	samples	sample	NOUN
fnp-5848	174	9	from	from	ADP
fnp-5848	174	10	patients	patient	NOUN
fnp-5848	174	11	diagnosed	diagnose	VERB
fnp-5848	174	12	with	with	ADP
fnp-5848	174	13	sca8	sca8	PROPN
fnp-5848	174	14	.	.	PUNCT
fnp-5848	175	1	sca8	sca8	PROPN
fnp-5848	175	2	is	be	AUX
fnp-5848	175	3	characterized	characterize	VERB
fnp-5848	175	4	by	by	ADP
fnp-5848	175	5	neuronal	neuronal	ADJ
fnp-5848	175	6	loss	loss	NOUN
fnp-5848	175	7	and	and	CCONJ
fnp-5848	175	8	gliosis	gliosis	NOUN
fnp-5848	175	9	predominantly	predominantly	ADV
fnp-5848	175	10	in	in	ADP
fnp-5848	175	11	the	the	DET
fnp-5848	175	12	cerebellum	cerebellum	NOUN
fnp-5848	175	13	and	and	CCONJ
fnp-5848	175	14	brainstem	brainstem	NOUN
fnp-5848	175	15	,	,	PUNCT
fnp-5848	175	16	which	which	PRON
fnp-5848	175	17	aligns	align	VERB
fnp-5848	175	18	with	with	ADP
fnp-5848	175	19	the	the	DET
fnp-5848	175	20	clinical	clinical	ADJ
fnp-5848	175	21	manifestations	manifestation	NOUN
fnp-5848	175	22	of	of	ADP
fnp-5848	175	23	the	the	DET
fnp-5848	175	24	disease	disease	NOUN
fnp-5848	175	25	.	.	PUNCT
fnp-5848	176	1	additionally	additionally	ADV
fnp-5848	176	2	,	,	PUNCT
fnp-5848	176	3	purkinje	purkinje	PROPN
fnp-5848	176	4	cell	cell	NOUN
fnp-5848	176	5	loss	loss	NOUN
fnp-5848	176	6	is	be	AUX
fnp-5848	176	7	a	a	DET
fnp-5848	176	8	consistent	consistent	ADJ
fnp-5848	176	9	finding	finding	NOUN
fnp-5848	176	10	,	,	PUNCT
fnp-5848	176	11	accompanied	accompany	VERB
fnp-5848	176	12	by	by	ADP
fnp-5848	176	13	bergmann	bergmann	PROPN
fnp-5848	176	14	gliosis	gliosis	PROPN
fnp-5848	176	15	and	and	CCONJ
fnp-5848	176	16	dentate	dentate	VERB
fnp-5848	176	17	nucleus	nucleus	ADJ
fnp-5848	176	18	degeneration	degeneration	NOUN
fnp-5848	176	19	.	.	PUNCT
fnp-5848	177	1	intriguingly	intriguingly	ADV
fnp-5848	177	2	,	,	PUNCT
fnp-5848	177	3	the	the	DET
fnp-5848	177	4	investigators	investigator	NOUN
fnp-5848	177	5	uncovered	uncover	VERB
fnp-5848	177	6	a	a	DET
fnp-5848	177	7	unique	unique	ADJ
fnp-5848	177	8	tauopathy	tauopathy	NOUN
fnp-5848	177	9	.	.	PUNCT
fnp-5848	178	1	unlike	unlike	ADP
fnp-5848	178	2	other	other	ADJ
fnp-5848	178	3	spinocerebellar	spinocerebellar	ADJ
fnp-5848	178	4	ataxias	ataxia	NOUN
fnp-5848	178	5	,	,	PUNCT
fnp-5848	178	6	sca8	sca8	PROPN
fnp-5848	178	7	exhibited	exhibit	VERB
fnp-5848	178	8	tau	tau	NOUN
fnp-5848	178	9	-	-	PUNCT
fnp-5848	178	10	positive	positive	ADJ
fnp-5848	178	11	neuronal	neuronal	ADJ
fnp-5848	178	12	and	and	CCONJ
fnp-5848	178	13	glial	glial	ADJ
fnp-5848	178	14	inclusions	inclusion	NOUN
fnp-5848	178	15	,	,	PUNCT
fnp-5848	178	16	particularly	particularly	ADV
fnp-5848	178	17	in	in	ADP
fnp-5848	178	18	the	the	DET
fnp-5848	178	19	brainstem	brainstem	NOUN
fnp-5848	178	20	and	and	CCONJ
fnp-5848	178	21	cerebellum	cerebellum	NOUN
fnp-5848	178	22	.	.	PUNCT
fnp-5848	179	1	this	this	DET
fnp-5848	179	2	finding	find	VERB
fnp-5848	179	3	not	not	PART
fnp-5848	179	4	only	only	ADV
fnp-5848	179	5	expands	expand	VERB
fnp-5848	179	6	the	the	DET
fnp-5848	179	7	neuropathological	neuropathological	ADJ
fnp-5848	179	8	spectrum	spectrum	NOUN
fnp-5848	179	9	of	of	ADP
fnp-5848	179	10	sca8	sca8	NOUN
fnp-5848	179	11	but	but	CCONJ
fnp-5848	179	12	also	also	ADV
fnp-5848	179	13	provides	provide	VERB
fnp-5848	179	14	new	new	ADJ
fnp-5848	179	15	insights	insight	NOUN
fnp-5848	179	16	into	into	ADP
fnp-5848	179	17	its	its	PRON
fnp-5848	179	18	underlying	underlie	VERB
fnp-5848	179	19	mechanisms	mechanism	NOUN
fnp-5848	179	20	,	,	PUNCT
fnp-5848	179	21	paving	pave	VERB
fnp-5848	179	22	the	the	DET
fnp-5848	179	23	way	way	NOUN
fnp-5848	179	24	for	for	ADP
fnp-5848	179	25	future	future	ADJ
fnp-5848	179	26	research	research	NOUN
fnp-5848	179	27	on	on	ADP
fnp-5848	179	28	targeted	target	VERB
fnp-5848	179	29	therapeutic	therapeutic	ADJ
fnp-5848	179	30	strategies	strategy	NOUN
fnp-5848	179	31	.	.	PUNCT
fnp-5848	180	1	intriguingly	intriguingly	ADV
fnp-5848	180	2	,	,	PUNCT
fnp-5848	180	3	sca8	sca8	PROPN
fnp-5848	180	4	is	be	AUX
fnp-5848	180	5	an	an	DET
fnp-5848	180	6	atypical	atypical	ADJ
fnp-5848	180	7	polyglutamine	polyglutamine	NOUN
fnp-5848	180	8	disorder	disorder	NOUN
fnp-5848	180	9	,	,	PUNCT
fnp-5848	180	10	with	with	ADP
fnp-5848	180	11	the	the	DET
fnp-5848	180	12	polyq	polyq	NOUN
fnp-5848	180	13	tract	tract	NOUN
fnp-5848	180	14	encoded	encode	VERB
fnp-5848	180	15	from	from	ADP
fnp-5848	180	16	the	the	DET
fnp-5848	180	17	anti	anti	ADJ
fnp-5848	180	18	-	-	ADJ
fnp-5848	180	19	sense	sense	ADJ
fnp-5848	180	20	strand	strand	NOUN
fnp-5848	180	21	,	,	PUNCT
fnp-5848	180	22	raising	raise	VERB
fnp-5848	180	23	a	a	DET
fnp-5848	180	24	possible	possible	ADJ
fnp-5848	180	25	explanation	explanation	NOUN
fnp-5848	180	26	for	for	ADP
fnp-5848	180	27	why	why	SCONJ
fnp-5848	180	28	the	the	DET
fnp-5848	180	29	tauopathy	tauopathy	NOUN
fnp-5848	180	30	described	describe	VERB
fnp-5848	180	31	for	for	ADP
fnp-5848	180	32	sca8	sca8	NOUN
fnp-5848	180	33	might	might	AUX
fnp-5848	180	34	be	be	AUX
fnp-5848	180	35	unique	unique	ADJ
fnp-5848	180	36	.	.	PUNCT
fnp-5848	181	1	the	the	DET
fnp-5848	181	2	study	study	NOUN
fnp-5848	181	3	emphasizes	emphasize	VERB
fnp-5848	181	4	the	the	DET
fnp-5848	181	5	importance	importance	NOUN
fnp-5848	181	6	of	of	ADP
fnp-5848	181	7	recognizing	recognize	VERB
fnp-5848	181	8	these	these	DET
fnp-5848	181	9	unique	unique	ADJ
fnp-5848	181	10	pathological	pathological	ADJ
fnp-5848	181	11	features	feature	NOUN
fnp-5848	181	12	to	to	PART
fnp-5848	181	13	improve	improve	VERB
fnp-5848	181	14	the	the	DET
fnp-5848	181	15	diagnosis	diagnosis	NOUN
fnp-5848	181	16	and	and	CCONJ
fnp-5848	181	17	understanding	understanding	NOUN
fnp-5848	181	18	of	of	ADP
fnp-5848	181	19	sca8	sca8	PROPN
fnp-5848	181	20	.	.	PUNCT
fnp-5848	182	1	funding	funding	NOUN
fnp-5848	182	2	statement	statement	NOUN
fnp-5848	182	3	this	this	DET
fnp-5848	182	4	work	work	NOUN
fnp-5848	182	5	was	be	AUX
fnp-5848	182	6	supported	support	VERB
fnp-5848	182	7	by	by	ADP
fnp-5848	182	8	funding	funding	NOUN
fnp-5848	182	9	from	from	ADP
fnp-5848	182	10	the	the	DET
fnp-5848	182	11	nih	nih	PROPN
fnp-5848	182	12	(	(	PUNCT
fnp-5848	182	13	r01ag054008	r01ag054008	PROPN
fnp-5848	182	14	,	,	PUNCT
fnp-5848	182	15	r01ns095252	r01ns095252	NOUN
fnp-5848	182	16	,	,	PUNCT
fnp-5848	182	17	r01ag062348	r01ag062348	NOUN
fnp-5848	182	18	,	,	PUNCT
fnp-5848	182	19	r01ns086736	r01ns086736	NOUN
fnp-5848	182	20	,	,	PUNCT
fnp-5848	182	21	u54ns115266	u54ns115266	PROPN
fnp-5848	182	22	,	,	PUNCT
fnp-5848	182	23	u54ns115322	u54ns115322	NOUN
fnp-5848	182	24	)	)	PUNCT
fnp-5848	182	25	as	as	ADV
fnp-5848	182	26	well	well	ADV
fnp-5848	182	27	as	as	ADP
fnp-5848	182	28	the	the	DET
fnp-5848	182	29	rainwater	rainwater	NOUN
fnp-5848	182	30	charitable	charitable	PROPN
fnp-5848	182	31	trust	trust	NOUN
fnp-5848	182	32	 	 	SPACE
fnp-5848	182	33	/	/	SYM
fnp-5848	182	34	 	 	SPACE
fnp-5848	182	35	tau	tau	PROPN
fnp-5848	182	36	consortium	consortium	NOUN
fnp-5848	182	37	,	,	PUNCT
fnp-5848	182	38	the	the	DET
fnp-5848	182	39	alexander	alexander	PROPN
fnp-5848	182	40	saint	saint	PROPN
fnp-5848	182	41	amand	amand	PROPN
fnp-5848	182	42	scholar	scholar	PROPN
fnp-5848	182	43	award	award	PROPN
fnp-5848	182	44	,	,	PUNCT
fnp-5848	182	45	the	the	DET
fnp-5848	182	46	karen	karen	PROPN
fnp-5848	182	47	strauss	strauss	PROPN
fnp-5848	182	48	cook	cook	PROPN
fnp-5848	182	49	research	research	NOUN
fnp-5848	182	50	scholar	scholar	NOUN
fnp-5848	182	51	award	award	NOUN
fnp-5848	182	52	,	,	PUNCT
fnp-5848	182	53	and	and	CCONJ
fnp-5848	182	54	a	a	DET
fnp-5848	182	55	generous	generous	ADJ
fnp-5848	182	56	gift	gift	NOUN
fnp-5848	182	57	from	from	ADP
fnp-5848	182	58	stuart	stuart	PROPN
fnp-5848	182	59	katz	katz	PROPN
fnp-5848	182	60	and	and	CCONJ
fnp-5848	182	61	dr	dr	PROPN
fnp-5848	182	62	.	.	PROPN
fnp-5848	182	63	jane	jane	PROPN
fnp-5848	182	64	martin	martin	PROPN
fnp-5848	182	65	.	.	PUNCT
fnp-5848	183	1	conflict	conflict	NOUN
fnp-5848	183	2	of	of	ADP
fnp-5848	183	3	interest	interest	NOUN
fnp-5848	183	4	the	the	DET
fnp-5848	183	5	author	author	NOUN
fnp-5848	183	6	reports	report	VERB
fnp-5848	183	7	no	no	DET
fnp-5848	183	8	conflicts	conflict	NOUN
fnp-5848	183	9	of	of	ADP
fnp-5848	183	10	interest	interest	NOUN
fnp-5848	183	11	.	.	PUNCT
fnp-5848	184	1	disclosure	disclosure	NOUN
fnp-5848	184	2	statement	statement	NOUN
fnp-5848	184	3	generative	generative	VERB
fnp-5848	184	4	artificial	artificial	ADJ
fnp-5848	184	5	intelligence	intelligence	NOUN
fnp-5848	184	6	tools	tool	NOUN
fnp-5848	184	7	,	,	PUNCT
fnp-5848	184	8	specifically	specifically	ADV
fnp-5848	184	9	openai	openai	PROPN
fnp-5848	184	10	's	's	PART
fnp-5848	184	11	gpt-4	gpt-4	NOUN
fnp-5848	184	12	,	,	PUNCT
fnp-5848	184	13	were	be	AUX
fnp-5848	184	14	used	use	VERB
fnp-5848	184	15	in	in	ADP
fnp-5848	184	16	the	the	DET
fnp-5848	184	17	preparation	preparation	NOUN
fnp-5848	184	18	of	of	ADP
fnp-5848	184	19	this	this	DET
fnp-5848	184	20	manuscript	manuscript	NOUN
fnp-5848	184	21	.	.	PUNCT
fnp-5848	185	1	these	these	DET
fnp-5848	185	2	tools	tool	NOUN
fnp-5848	185	3	assisted	assist	VERB
fnp-5848	185	4	in	in	ADP
fnp-5848	185	5	drafting	drafting	NOUN
fnp-5848	185	6	and	and	CCONJ
fnp-5848	185	7	refining	refining	NOUN
fnp-5848	185	8	portions	portion	NOUN
fnp-5848	185	9	of	of	ADP
fnp-5848	185	10	the	the	DET
fnp-5848	185	11	text	text	NOUN
fnp-5848	185	12	.	.	PUNCT
fnp-5848	186	1	the	the	DET
fnp-5848	186	2	final	final	ADJ
fnp-5848	186	3	content	content	NOUN
fnp-5848	186	4	has	have	AUX
fnp-5848	186	5	been	be	AUX
fnp-5848	186	6	reviewed	review	VERB
fnp-5848	186	7	and	and	CCONJ
fnp-5848	186	8	edited	edit	VERB
fnp-5848	186	9	by	by	ADP
fnp-5848	186	10	the	the	DET
fnp-5848	186	11	author	author	NOUN
fnp-5848	186	12	to	to	PART
fnp-5848	186	13	ensure	ensure	VERB
fnp-5848	186	14	its	its	PRON
fnp-5848	186	15	accuracy	accuracy	NOUN
fnp-5848	186	16	,	,	PUNCT
fnp-5848	186	17	originality	originality	NOUN
fnp-5848	186	18	,	,	PUNCT
fnp-5848	186	19	and	and	CCONJ
fnp-5848	186	20	compliance	compliance	NOUN
fnp-5848	186	21	with	with	ADP
fnp-5848	186	22	the	the	DET
fnp-5848	186	23	journal	journal	NOUN
fnp-5848	186	24	's	's	PART
fnp-5848	186	25	authorship	authorship	NOUN
fnp-5848	186	26	and	and	CCONJ
fnp-5848	186	27	integrity	integrity	NOUN
fnp-5848	186	28	guidelines	guideline	NOUN
fnp-5848	186	29	.	.	PUNCT
fnp-5848	187	1	the	the	DET
fnp-5848	187	2	author	author	NOUN
fnp-5848	187	3	takes	take	VERB
fnp-5848	187	4	full	full	ADJ
fnp-5848	187	5	responsibility	responsibility	NOUN
fnp-5848	187	6	for	for	ADP
fnp-5848	187	7	the	the	DET
fnp-5848	187	8	content	content	NOUN
fnp-5848	187	9	of	of	ADP
fnp-5848	187	10	the	the	DET
fnp-5848	187	11	manuscript	manuscript	NOUN
fnp-5848	187	12	.	.	PUNCT
fnp-5848	188	1	references	reference	NOUN
fnp-5848	188	2	chen	chen	PROPN
fnp-5848	188	3	,	,	PUNCT
fnp-5848	188	4	x.	x.	PROPN
fnp-5848	188	5	,	,	PUNCT
fnp-5848	188	6	firulyova	firulyova	PROPN
fnp-5848	188	7	,	,	PUNCT
fnp-5848	188	8	m.	m.	NOUN
fnp-5848	188	9	,	,	PUNCT
fnp-5848	188	10	manis	manis	PROPN
fnp-5848	188	11	,	,	PUNCT
fnp-5848	188	12	m.	m.	NOUN
fnp-5848	188	13	,	,	PUNCT
fnp-5848	188	14	herz	herz	PROPN
fnp-5848	188	15	,	,	PUNCT
fnp-5848	188	16	j.	j.	PROPN
fnp-5848	188	17	,	,	PUNCT
fnp-5848	188	18	smirnov	smirnov	PROPN
fnp-5848	188	19	,	,	PUNCT
fnp-5848	188	20	i.	i.	PROPN
fnp-5848	188	21	,	,	PUNCT
fnp-5848	188	22	aladyeva	aladyeva	PROPN
fnp-5848	188	23	,	,	PUNCT
fnp-5848	188	24	e.	e.	PROPN
fnp-5848	188	25	,	,	PUNCT
fnp-5848	188	26	wang	wang	PROPN
fnp-5848	188	27	,	,	PUNCT
fnp-5848	188	28	c.	c.	PROPN
fnp-5848	188	29	,	,	PUNCT
fnp-5848	188	30	bao	bao	PROPN
fnp-5848	188	31	,	,	PUNCT
fnp-5848	188	32	x.	x.	PROPN
fnp-5848	188	33	,	,	PUNCT
fnp-5848	188	34	finn	finn	PROPN
fnp-5848	188	35	,	,	PUNCT
fnp-5848	188	36	m.	m.	PROPN
fnp-5848	188	37	b.	b.	PROPN
fnp-5848	188	38	,	,	PUNCT
fnp-5848	188	39	hu	hu	PROPN
fnp-5848	188	40	,	,	PUNCT
fnp-5848	188	41	h.	h.	PROPN
fnp-5848	188	42	,	,	PUNCT
fnp-5848	188	43	shchukina	shchukina	PROPN
fnp-5848	188	44	,	,	PUNCT
fnp-5848	188	45	i.	i.	PROPN
fnp-5848	188	46	,	,	PUNCT
fnp-5848	188	47	kim	kim	PROPN
fnp-5848	188	48	,	,	PUNCT
fnp-5848	188	49	m.	m.	PROPN
fnp-5848	188	50	w.	w.	PROPN
fnp-5848	188	51	,	,	PUNCT
fnp-5848	188	52	yuede	yuede	PROPN
fnp-5848	188	53	,	,	PUNCT
fnp-5848	188	54	c.	c.	NOUN
fnp-5848	188	55	m.	m.	NOUN
fnp-5848	188	56	,	,	PUNCT
fnp-5848	188	57	kipnis	kipnis	PROPN
fnp-5848	188	58	,	,	PUNCT
fnp-5848	188	59	j.	j.	PROPN
fnp-5848	188	60	,	,	PUNCT
fnp-5848	188	61	artyomov	artyomov	PROPN
fnp-5848	188	62	,	,	PUNCT
fnp-5848	188	63	m.	m.	NOUN
fnp-5848	188	64	n.	n.	PROPN
fnp-5848	188	65	,	,	PUNCT
fnp-5848	188	66	ulrich	ulrich	PROPN
fnp-5848	188	67	,	,	PUNCT
fnp-5848	188	68	j.	j.	PROPN
fnp-5848	188	69	d.	d.	PROPN
fnp-5848	188	70	,	,	PUNCT
fnp-5848	188	71	&	&	CCONJ
fnp-5848	188	72	holtzman	holtzman	PROPN
fnp-5848	188	73	,	,	PUNCT
fnp-5848	188	74	d.	d.	PROPN
fnp-5848	188	75	m.	m.	PROPN
fnp-5848	188	76	(	(	PUNCT
fnp-5848	188	77	2023	2023	NUM
fnp-5848	188	78	)	)	PUNCT
fnp-5848	188	79	.	.	PUNCT
fnp-5848	189	1	microglia	microglia	ADJ
fnp-5848	189	2	-	-	PUNCT
fnp-5848	189	3	mediated	mediate	VERB
fnp-5848	189	4	t	t	NOUN
fnp-5848	189	5	cell	cell	NOUN
fnp-5848	189	6	infiltration	infiltration	NOUN
fnp-5848	189	7	drives	drive	VERB
fnp-5848	189	8	neurodegeneration	neurodegeneration	NOUN
fnp-5848	189	9	in	in	ADP
fnp-5848	189	10	tauopathy	tauopathy	NOUN
fnp-5848	189	11	.	.	PUNCT
fnp-5848	190	1	nature	nature	NOUN
fnp-5848	190	2	,	,	PUNCT
fnp-5848	190	3	615(7953	615(7953	NUM
fnp-5848	190	4	)	)	PUNCT
fnp-5848	190	5	,	,	PUNCT
fnp-5848	190	6	668–677	668–677	NUM
fnp-5848	190	7	.	.	PUNCT
fnp-5848	191	1	https://doi.org/10.1038/s41586-023-05788-0	https://doi.org/10.1038/s41586-023-05788-0	PROPN
fnp-5848	191	2	choudhury	choudhury	PROPN
fnp-5848	191	3	,	,	PUNCT
fnp-5848	191	4	p.	p.	PROPN
fnp-5848	191	5	,	,	PUNCT
fnp-5848	191	6	zhang	zhang	PROPN
fnp-5848	191	7	,	,	PUNCT
fnp-5848	191	8	n.	n.	PROPN
fnp-5848	191	9	,	,	PUNCT
fnp-5848	191	10	adler	adler	PROPN
fnp-5848	191	11	,	,	PUNCT
fnp-5848	191	12	c.	c.	PROPN
fnp-5848	191	13	h.	h.	PROPN
fnp-5848	191	14	,	,	PUNCT
fnp-5848	191	15	chen	chen	PROPN
fnp-5848	191	16	,	,	PUNCT
fnp-5848	191	17	k.	k.	PROPN
fnp-5848	191	18	,	,	PUNCT
fnp-5848	191	19	belden	belden	PROPN
fnp-5848	191	20	,	,	PUNCT
fnp-5848	191	21	c.	c.	PROPN
fnp-5848	191	22	,	,	PUNCT
fnp-5848	191	23	driverdunckley	driverdunckley	PROPN
fnp-5848	191	24	,	,	PUNCT
fnp-5848	191	25	e.	e.	PROPN
fnp-5848	191	26	,	,	PUNCT
fnp-5848	191	27	mehta	mehta	PROPN
fnp-5848	191	28	,	,	PUNCT
fnp-5848	191	29	s.	s.	PROPN
fnp-5848	191	30	h.	h.	PROPN
fnp-5848	191	31	,	,	PUNCT
fnp-5848	191	32	shprecher	shprecher	PROPN
fnp-5848	191	33	,	,	PUNCT
fnp-5848	191	34	d.	d.	PROPN
fnp-5848	191	35	r.	r.	PROPN
fnp-5848	191	36	,	,	PUNCT
fnp-5848	191	37	serrano	serrano	PROPN
fnp-5848	191	38	,	,	PUNCT
fnp-5848	191	39	g.	g.	PROPN
fnp-5848	191	40	e.	e.	PROPN
fnp-5848	191	41	,	,	PUNCT
fnp-5848	191	42	shill	shill	PROPN
fnp-5848	191	43	,	,	PUNCT
fnp-5848	191	44	h.	h.	PROPN
fnp-5848	191	45	a.	a.	PROPN
fnp-5848	191	46	,	,	PUNCT
fnp-5848	191	47	beach	beach	NOUN
fnp-5848	191	48	,	,	PUNCT
fnp-5848	191	49	t.	t.	PROPN
fnp-5848	191	50	g.	g.	PROPN
fnp-5848	191	51	,	,	PUNCT
fnp-5848	191	52	&	&	CCONJ
fnp-5848	191	53	atri	atri	PROPN
fnp-5848	191	54	,	,	PUNCT
fnp-5848	191	55	a.	a.	NOUN
fnp-5848	191	56	(	(	PUNCT
fnp-5848	191	57	2023	2023	NUM
fnp-5848	191	58	)	)	PUNCT
fnp-5848	191	59	.	.	PUNCT
fnp-5848	192	1	longitudinal	longitudinal	ADJ
fnp-5848	192	2	motor	motor	NOUN
fnp-5848	192	3	decline	decline	NOUN
fnp-5848	192	4	in	in	ADP
fnp-5848	192	5	dementia	dementia	NOUN
fnp-5848	192	6	with	with	ADP
fnp-5848	192	7	lewy	lewy	PROPN
fnp-5848	192	8	bodies	body	NOUN
fnp-5848	192	9	,	,	PUNCT
fnp-5848	192	10	parkinson	parkinson	NOUN
fnp-5848	192	11	disease	disease	NOUN
fnp-5848	192	12	dementia	dementia	NOUN
fnp-5848	192	13	,	,	PUNCT
fnp-5848	192	14	and	and	CCONJ
fnp-5848	192	15	alzheimer	alzheimer	PROPN
fnp-5848	192	16	’s	’s	PART
fnp-5848	192	17	dementia	dementia	NOUN
fnp-5848	192	18	in	in	ADP
fnp-5848	192	19	a	a	DET
fnp-5848	192	20	community	community	NOUN
fnp-5848	192	21	autopsy	autopsy	ADJ
fnp-5848	192	22	cohort	cohort	NOUN
fnp-5848	192	23	.	.	PUNCT
fnp-5848	193	1	alzheimer	alzheimer	PROPN
fnp-5848	193	2	’s	’s	PART
fnp-5848	193	3	&	&	CCONJ
fnp-5848	193	4	dementia	dementia	PROPN
fnp-5848	193	5	:	:	PUNCT
fnp-5848	193	6	the	the	DET
fnp-5848	193	7	journal	journal	NOUN
fnp-5848	193	8	of	of	ADP
fnp-5848	193	9	the	the	DET
fnp-5848	193	10	alzheimer	alzheimer	PROPN
fnp-5848	193	11	’s	’s	PROPN
fnp-5848	193	12	association	association	NOUN
fnp-5848	193	13	,	,	PUNCT
fnp-5848	193	14	19(10	19(10	NUM
fnp-5848	193	15	)	)	PUNCT
fnp-5848	193	16	,	,	PUNCT
fnp-5848	193	17	4377–4387	4377–4387	NUM
fnp-5848	193	18	.	.	PUNCT
fnp-5848	194	1	https://doi.org/10.1002/alz.13357	https://doi.org/10.1002/alz.13357	PROPN
fnp-5848	194	2	grodstein	grodstein	PROPN
fnp-5848	194	3	,	,	PUNCT
fnp-5848	194	4	f.	f.	PROPN
fnp-5848	194	5	,	,	PUNCT
fnp-5848	194	6	leurgans	leurgans	PROPN
fnp-5848	194	7	,	,	PUNCT
fnp-5848	194	8	s.	s.	PROPN
fnp-5848	194	9	e.	e.	PROPN
fnp-5848	194	10	,	,	PUNCT
fnp-5848	194	11	capuano	capuano	PROPN
fnp-5848	194	12	,	,	PUNCT
fnp-5848	194	13	a.	a.	PROPN
fnp-5848	194	14	w.	w.	PROPN
fnp-5848	194	15	,	,	PUNCT
fnp-5848	194	16	schneider	schneider	PROPN
fnp-5848	194	17	,	,	PUNCT
fnp-5848	194	18	j.	j.	PROPN
fnp-5848	194	19	a.	a.	PROPN
fnp-5848	194	20	,	,	PUNCT
fnp-5848	194	21	&	&	CCONJ
fnp-5848	194	22	bennett	bennett	PROPN
fnp-5848	194	23	,	,	PUNCT
fnp-5848	194	24	d.	d.	PROPN
fnp-5848	194	25	a.	a.	PROPN
fnp-5848	194	26	(	(	PUNCT
fnp-5848	194	27	2023	2023	NUM
fnp-5848	194	28	)	)	PUNCT
fnp-5848	194	29	.	.	PUNCT
fnp-5848	195	1	trends	trend	NOUN
fnp-5848	195	2	in	in	ADP
fnp-5848	195	3	postmortem	postmortem	NOUN
fnp-5848	195	4	neurodegenerative	neurodegenerative	ADJ
fnp-5848	195	5	and	and	CCONJ
fnp-5848	195	6	cerebrovascular	cerebrovascular	ADJ
fnp-5848	195	7	neuropathologies	neuropathologie	NOUN
fnp-5848	195	8	over	over	ADP
fnp-5848	195	9	25	25	NUM
fnp-5848	195	10	years	year	NOUN
fnp-5848	195	11	.	.	PUNCT
fnp-5848	196	1	jama	jama	PROPN
fnp-5848	196	2	neurology	neurology	PROPN
fnp-5848	196	3	,	,	PUNCT
fnp-5848	196	4	80(4	80(4	NUM
fnp-5848	196	5	)	)	PUNCT
fnp-5848	196	6	,	,	PUNCT
fnp-5848	196	7	370–376	370–376	NUM
fnp-5848	196	8	.	.	PUNCT
fnp-5848	197	1	https://doi.org/10.1001/jamaneurol.2022.5416	https://doi.org/10.1001/jamaneurol.2022.5416	PROPN
fnp-5848	197	2	levine	levine	PROPN
fnp-5848	197	3	,	,	PUNCT
fnp-5848	197	4	k.	k.	PROPN
fnp-5848	197	5	s.	s.	PROPN
fnp-5848	197	6	,	,	PUNCT
fnp-5848	197	7	leonard	leonard	PROPN
fnp-5848	197	8	,	,	PUNCT
fnp-5848	197	9	h.	h.	PROPN
fnp-5848	197	10	l.	l.	PROPN
fnp-5848	197	11	,	,	PUNCT
fnp-5848	197	12	blauwendraat	blauwendraat	PROPN
fnp-5848	197	13	,	,	PUNCT
fnp-5848	197	14	c.	c.	PROPN
fnp-5848	197	15	,	,	PUNCT
fnp-5848	197	16	iwaki	iwaki	NOUN
fnp-5848	197	17	,	,	PUNCT
fnp-5848	197	18	h.	h.	PROPN
fnp-5848	197	19	,	,	PUNCT
fnp-5848	197	20	johnson	johnson	PROPN
fnp-5848	197	21	,	,	PUNCT
fnp-5848	197	22	n.	n.	PROPN
fnp-5848	197	23	,	,	PUNCT
fnp-5848	197	24	bandres	bandre	NOUN
fnp-5848	197	25	-	-	PUNCT
fnp-5848	197	26	ciga	ciga	NOUN
fnp-5848	197	27	,	,	PUNCT
fnp-5848	197	28	s.	s.	PROPN
fnp-5848	197	29	,	,	PUNCT
fnp-5848	197	30	ferrucci	ferrucci	PROPN
fnp-5848	197	31	,	,	PUNCT
fnp-5848	197	32	l.	l.	PROPN
fnp-5848	197	33	,	,	PUNCT
fnp-5848	197	34	faghri	faghri	PROPN
fnp-5848	197	35	,	,	PUNCT
fnp-5848	197	36	f.	f.	PROPN
fnp-5848	197	37	,	,	PUNCT
fnp-5848	197	38	singleton	singleton	PROPN
fnp-5848	197	39	,	,	PUNCT
fnp-5848	197	40	a.	a.	PROPN
fnp-5848	197	41	b.	b.	PROPN
fnp-5848	197	42	,	,	PUNCT
fnp-5848	197	43	&	&	CCONJ
fnp-5848	197	44	nalls	nalls	PROPN
fnp-5848	197	45	,	,	PUNCT
fnp-5848	197	46	m.	m.	NOUN
fnp-5848	197	47	a.	a.	NOUN
fnp-5848	197	48	(	(	PUNCT
fnp-5848	197	49	2023	2023	NUM
fnp-5848	197	50	)	)	PUNCT
fnp-5848	197	51	.	.	PUNCT
fnp-5848	198	1	virus	virus	NOUN
fnp-5848	198	2	exposure	exposure	NOUN
fnp-5848	198	3	and	and	CCONJ
fnp-5848	198	4	neurodegenerative	neurodegenerative	ADJ
fnp-5848	198	5	disease	disease	NOUN
fnp-5848	198	6	risk	risk	NOUN
fnp-5848	198	7	across	across	ADP
fnp-5848	198	8	national	national	ADJ
fnp-5848	198	9	biobanks	biobank	NOUN
fnp-5848	198	10	.	.	PUNCT
fnp-5848	199	1	neuron	neuron	PROPN
fnp-5848	199	2	,	,	PUNCT
fnp-5848	199	3	111(7	111(7	NUM
fnp-5848	199	4	)	)	PUNCT
fnp-5848	199	5	,	,	PUNCT
fnp-5848	199	6	1086	1086	NUM
fnp-5848	199	7	-	-	SYM
fnp-5848	199	8	1093.e2	1093.e2	NUM
fnp-5848	199	9	.	.	PUNCT
fnp-5848	200	1	https://doi.org/10.1016/j.neuron.2022.12.029	https://doi.org/10.1016/j.neuron.2022.12.029	PROPN
fnp-5848	200	2	marx	marx	PROPN
fnp-5848	200	3	,	,	PUNCT
fnp-5848	200	4	g.	g.	PROPN
fnp-5848	200	5	a.	a.	PROPN
fnp-5848	200	6	,	,	PUNCT
fnp-5848	200	7	kauffman	kauffman	PROPN
fnp-5848	200	8	,	,	PUNCT
fnp-5848	200	9	j.	j.	PROPN
fnp-5848	200	10	,	,	PUNCT
fnp-5848	200	11	mckenzie	mckenzie	PROPN
fnp-5848	200	12	,	,	PUNCT
fnp-5848	200	13	a.	a.	NOUN
fnp-5848	200	14	t.	t.	PROPN
fnp-5848	200	15	,	,	PUNCT
fnp-5848	200	16	koenigsberg	koenigsberg	PROPN
fnp-5848	200	17	,	,	PUNCT
fnp-5848	200	18	d.	d.	PROPN
fnp-5848	200	19	g.	g.	PROPN
fnp-5848	200	20	,	,	PUNCT
fnp-5848	200	21	mcmillan	mcmillan	PROPN
fnp-5848	200	22	,	,	PUNCT
fnp-5848	200	23	c.	c.	PROPN
fnp-5848	200	24	t.	t.	PROPN
fnp-5848	200	25	,	,	PUNCT
fnp-5848	200	26	morgello	morgello	PROPN
fnp-5848	200	27	,	,	PUNCT
fnp-5848	200	28	s.	s.	PROPN
fnp-5848	200	29	,	,	PUNCT
fnp-5848	200	30	karlovich	karlovich	PROPN
fnp-5848	200	31	,	,	PUNCT
fnp-5848	200	32	e.	e.	PROPN
fnp-5848	200	33	,	,	PUNCT
fnp-5848	200	34	insausti	insausti	PROPN
fnp-5848	200	35	,	,	PUNCT
fnp-5848	200	36	r.	r.	PROPN
fnp-5848	200	37	,	,	PUNCT
fnp-5848	200	38	richardson	richardson	PROPN
fnp-5848	200	39	,	,	PUNCT
fnp-5848	200	40	t.	t.	PROPN
fnp-5848	200	41	e.	e.	PROPN
fnp-5848	200	42	,	,	PUNCT
fnp-5848	200	43	walker	walker	PROPN
fnp-5848	200	44	,	,	PUNCT
fnp-5848	200	45	j.	j.	PROPN
fnp-5848	200	46	m.	m.	PROPN
fnp-5848	200	47	,	,	PUNCT
fnp-5848	200	48	white	white	PROPN
fnp-5848	200	49	,	,	PUNCT
fnp-5848	200	50	c.	c.	PROPN
fnp-5848	200	51	l.	l.	PROPN
fnp-5848	200	52	,	,	PUNCT
fnp-5848	200	53	babrowicz	babrowicz	PROPN
fnp-5848	200	54	,	,	PUNCT
fnp-5848	200	55	b.	b.	PROPN
fnp-5848	200	56	m.	m.	PROPN
fnp-5848	200	57	,	,	PUNCT
fnp-5848	200	58	shen	shen	PROPN
fnp-5848	200	59	,	,	PUNCT
fnp-5848	200	60	l.	l.	PROPN
fnp-5848	200	61	,	,	PUNCT
fnp-5848	200	62	mckee	mckee	PROPN
fnp-5848	200	63	,	,	PUNCT
fnp-5848	200	64	a.	a.	PROPN
fnp-5848	200	65	c.	c.	PROPN
fnp-5848	200	66	,	,	PUNCT
fnp-5848	200	67	stein	stein	PROPN
fnp-5848	200	68	,	,	PUNCT
fnp-5848	200	69	t.	t.	PROPN
fnp-5848	200	70	d.	d.	PROPN
fnp-5848	200	71	,	,	PUNCT
fnp-5848	200	72	part	part	NOUN
fnp-5848	200	73	working	working	NOUN
fnp-5848	200	74	group	group	NOUN
fnp-5848	200	75	,	,	PUNCT
fnp-5848	200	76	farrell	farrell	PROPN
fnp-5848	200	77	,	,	PUNCT
fnp-5848	200	78	k.	k.	PROPN
fnp-5848	200	79	,	,	PUNCT
fnp-5848	200	80	&	&	CCONJ
fnp-5848	200	81	crary	crary	PROPN
fnp-5848	200	82	,	,	PUNCT
fnp-5848	200	83	j.	j.	PROPN
fnp-5848	200	84	f.	f.	PROPN
fnp-5848	200	85	(	(	PUNCT
fnp-5848	200	86	2023	2023	NUM
fnp-5848	200	87	)	)	PUNCT
fnp-5848	200	88	.	.	PUNCT
fnp-5848	201	1	histopathologic	histopathologic	ADJ
fnp-5848	201	2	brain	brain	NOUN
fnp-5848	201	3	age	age	NOUN
fnp-5848	201	4	estimation	estimation	NOUN
fnp-5848	201	5	via	via	ADP
fnp-5848	201	6	multiple	multiple	ADJ
fnp-5848	201	7	instance	instance	NOUN
fnp-5848	201	8	learning	learning	NOUN
fnp-5848	201	9	.	.	PUNCT
fnp-5848	202	1	acta	acta	PROPN
fnp-5848	202	2	neuropathologica	neuropathologica	PROPN
fnp-5848	202	3	,	,	PUNCT
fnp-5848	202	4	146(6	146(6	NUM
fnp-5848	202	5	)	)	PUNCT
fnp-5848	202	6	,	,	PUNCT
fnp-5848	202	7	785–802	785–802	NUM
fnp-5848	202	8	.	.	PROPN
fnp-5848	202	9	https://doi.org/10.1007/s00401-023-02636-3	https://doi.org/10.1007/s00401-023-02636-3	NUM
fnp-5848	202	10	mckee	mckee	PROPN
fnp-5848	202	11	,	,	PUNCT
fnp-5848	202	12	a.	a.	PROPN
fnp-5848	202	13	c.	c.	PROPN
fnp-5848	202	14	,	,	PUNCT
fnp-5848	202	15	mez	mez	PROPN
fnp-5848	202	16	,	,	PUNCT
fnp-5848	202	17	j.	j.	PROPN
fnp-5848	202	18	,	,	PUNCT
fnp-5848	202	19	abdolmohammadi	abdolmohammadi	PROPN
fnp-5848	202	20	,	,	PUNCT
fnp-5848	202	21	b.	b.	PROPN
fnp-5848	202	22	,	,	PUNCT
fnp-5848	202	23	butler	butler	PROPN
fnp-5848	202	24	,	,	PUNCT
fnp-5848	202	25	m.	m.	NOUN
fnp-5848	202	26	,	,	PUNCT
fnp-5848	202	27	huber	huber	PROPN
fnp-5848	202	28	,	,	PUNCT
fnp-5848	202	29	b.	b.	PROPN
fnp-5848	202	30	r.	r.	PROPN
fnp-5848	202	31	,	,	PUNCT
fnp-5848	202	32	uretsky	uretsky	PROPN
fnp-5848	202	33	,	,	PUNCT
fnp-5848	202	34	m.	m.	NOUN
fnp-5848	202	35	,	,	PUNCT
fnp-5848	202	36	babcock	babcock	PROPN
fnp-5848	202	37	,	,	PUNCT
fnp-5848	202	38	k.	k.	PROPN
fnp-5848	202	39	,	,	PUNCT
fnp-5848	202	40	cherry	cherry	PROPN
fnp-5848	202	41	,	,	PUNCT
fnp-5848	202	42	j.	j.	PROPN
fnp-5848	202	43	d.	d.	PROPN
fnp-5848	202	44	,	,	PUNCT
fnp-5848	202	45	alvarez	alvarez	PROPN
fnp-5848	202	46	,	,	PUNCT
fnp-5848	202	47	v.	v.	PROPN
fnp-5848	202	48	e.	e.	PROPN
fnp-5848	202	49	,	,	PUNCT
fnp-5848	202	50	martin	martin	PROPN
fnp-5848	202	51	,	,	PUNCT
fnp-5848	202	52	b.	b.	PROPN
fnp-5848	202	53	,	,	PUNCT
fnp-5848	202	54	tripodis	tripodi	NOUN
fnp-5848	202	55	,	,	PUNCT
fnp-5848	202	56	y.	y.	PROPN
fnp-5848	202	57	,	,	PUNCT
fnp-5848	202	58	palmisano	palmisano	INTJ
fnp-5848	202	59	,	,	PUNCT
fnp-5848	202	60	j.	j.	PROPN
fnp-5848	202	61	n.	n.	PROPN
fnp-5848	202	62	,	,	PUNCT
fnp-5848	202	63	cormier	cormier	PROPN
fnp-5848	202	64	,	,	PUNCT
fnp-5848	202	65	k.	k.	PROPN
fnp-5848	202	66	a.	a.	PROPN
fnp-5848	202	67	,	,	PUNCT
fnp-5848	202	68	kubilus	kubilus	PROPN
fnp-5848	202	69	,	,	PUNCT
fnp-5848	202	70	c.	c.	PROPN
fnp-5848	202	71	a.	a.	PROPN
fnp-5848	202	72	,	,	PUNCT
fnp-5848	202	73	nicks	nick	NOUN
fnp-5848	202	74	,	,	PUNCT
fnp-5848	202	75	r.	r.	PROPN
fnp-5848	202	76	,	,	PUNCT
fnp-5848	202	77	kirsch	kirsch	PROPN
fnp-5848	202	78	,	,	PUNCT
fnp-5848	202	79	d.	d.	PROPN
fnp-5848	202	80	,	,	PUNCT
fnp-5848	202	81	mahar	mahar	PROPN
fnp-5848	202	82	,	,	PUNCT
fnp-5848	202	83	i.	i.	PROPN
fnp-5848	202	84	,	,	PUNCT
fnp-5848	202	85	mchale	mchale	PROPN
fnp-5848	202	86	,	,	PUNCT
fnp-5848	202	87	l.	l.	PROPN
fnp-5848	202	88	,	,	PUNCT
fnp-5848	202	89	nowinski	nowinski	NOUN
fnp-5848	202	90	,	,	PUNCT
fnp-5848	202	91	c.	c.	NOUN
fnp-5848	202	92	,	,	PUNCT
fnp-5848	202	93	…	…	PUNCT
fnp-5848	202	94	alosco	alosco	PROPN
fnp-5848	202	95	,	,	PUNCT
fnp-5848	202	96	m.	m.	NOUN
fnp-5848	202	97	l.	l.	PROPN
fnp-5848	202	98	(	(	PUNCT
fnp-5848	202	99	2023	2023	NUM
fnp-5848	202	100	)	)	PUNCT
fnp-5848	202	101	.	.	PUNCT
fnp-5848	203	1	neuropathologic	neuropathologic	ADJ
fnp-5848	203	2	and	and	CCONJ
fnp-5848	203	3	clinical	clinical	ADJ
fnp-5848	203	4	findings	finding	NOUN
fnp-5848	203	5	in	in	ADP
fnp-5848	203	6	young	young	ADJ
fnp-5848	203	7	contact	contact	NOUN
fnp-5848	203	8	sport	sport	NOUN
fnp-5848	203	9	athletes	athlete	NOUN
fnp-5848	203	10	exposed	expose	VERB
fnp-5848	203	11	to	to	ADP
fnp-5848	203	12	repetitive	repetitive	ADJ
fnp-5848	203	13	head	head	NOUN
fnp-5848	203	14	impacts	impact	NOUN
fnp-5848	203	15	.	.	PUNCT
fnp-5848	204	1	jama	jama	PROPN
fnp-5848	204	2	neurology	neurology	NOUN
fnp-5848	204	3	,	,	PUNCT
fnp-5848	204	4	80(10	80(10	NUM
fnp-5848	204	5	)	)	PUNCT
fnp-5848	204	6	,	,	PUNCT
fnp-5848	204	7	1037	1037	NUM
fnp-5848	204	8	–	–	PUNCT
fnp-5848	204	9	1050	1050	NUM
fnp-5848	204	10	.	.	PUNCT
fnp-5848	205	1	https://doi.org/10.1001/jamaneurol.2023.2907	https://doi.org/10.1001/jamaneurol.2023.2907	PROPN
fnp-5848	205	2	nicks	nick	NOUN
fnp-5848	205	3	,	,	PUNCT
fnp-5848	205	4	r.	r.	PROPN
fnp-5848	205	5	,	,	PUNCT
fnp-5848	205	6	clement	clement	PROPN
fnp-5848	205	7	,	,	PUNCT
fnp-5848	205	8	n.	n.	PROPN
fnp-5848	205	9	f.	f.	PROPN
fnp-5848	205	10	,	,	PUNCT
fnp-5848	205	11	alvarez	alvarez	PROPN
fnp-5848	205	12	,	,	PUNCT
fnp-5848	205	13	v.	v.	PROPN
fnp-5848	205	14	e.	e.	PROPN
fnp-5848	205	15	,	,	PUNCT
fnp-5848	205	16	tripodis	tripodi	NOUN
fnp-5848	205	17	,	,	PUNCT
fnp-5848	205	18	y.	y.	PROPN
fnp-5848	205	19	,	,	PUNCT
fnp-5848	205	20	baucom	baucom	PROPN
fnp-5848	205	21	,	,	PUNCT
fnp-5848	205	22	z.	z.	PROPN
fnp-5848	205	23	h.	h.	PROPN
fnp-5848	205	24	,	,	PUNCT
fnp-5848	205	25	huber	huber	PROPN
fnp-5848	205	26	,	,	PUNCT
fnp-5848	205	27	b.	b.	PROPN
fnp-5848	205	28	r.	r.	PROPN
fnp-5848	205	29	,	,	PUNCT
fnp-5848	205	30	mez	mez	PROPN
fnp-5848	205	31	,	,	PUNCT
fnp-5848	205	32	j.	j.	PROPN
fnp-5848	205	33	,	,	PUNCT
fnp-5848	205	34	alosco	alosco	PROPN
fnp-5848	205	35	,	,	PUNCT
fnp-5848	205	36	m.	m.	PROPN
fnp-5848	205	37	l.	l.	PROPN
fnp-5848	205	38	,	,	PUNCT
fnp-5848	205	39	aytan	aytan	PROPN
fnp-5848	205	40	,	,	PUNCT
fnp-5848	205	41	n.	n.	NOUN
fnp-5848	205	42	,	,	PUNCT
fnp-5848	205	43	cherry	cherry	PROPN
fnp-5848	205	44	,	,	PUNCT
fnp-5848	205	45	j.	j.	PROPN
fnp-5848	205	46	d.	d.	PROPN
fnp-5848	205	47	,	,	PUNCT
fnp-5848	205	48	cormier	cormier	PROPN
fnp-5848	205	49	,	,	PUNCT
fnp-5848	205	50	k.	k.	PROPN
fnp-5848	205	51	a.	a.	PROPN
fnp-5848	205	52	,	,	PUNCT
fnp-5848	205	53	kubilius	kubilius	PROPN
fnp-5848	205	54	,	,	PUNCT
fnp-5848	205	55	c.	c.	PROPN
fnp-5848	205	56	,	,	PUNCT
fnp-5848	205	57	mathias	mathias	PROPN
fnp-5848	205	58	,	,	PUNCT
fnp-5848	205	59	r.	r.	PROPN
fnp-5848	205	60	,	,	PUNCT
fnp-5848	205	61	svirsky	svirsky	PROPN
fnp-5848	205	62	,	,	PUNCT
fnp-5848	205	63	s.	s.	PROPN
fnp-5848	205	64	e.	e.	PROPN
fnp-5848	205	65	,	,	PUNCT
fnp-5848	205	66	pothast	pothast	NOUN
fnp-5848	205	67	,	,	PUNCT
fnp-5848	205	68	m.	m.	NOUN
fnp-5848	205	69	j.	j.	PROPN
fnp-5848	205	70	,	,	PUNCT
fnp-5848	205	71	hildebrandt	hildebrandt	PROPN
fnp-5848	205	72	,	,	PUNCT
fnp-5848	205	73	a.	a.	NOUN
fnp-5848	205	74	m.	m.	NOUN
fnp-5848	205	75	,	,	PUNCT
fnp-5848	205	76	chung	chung	PROPN
fnp-5848	205	77	,	,	PUNCT
fnp-5848	205	78	j.	j.	PROPN
fnp-5848	205	79	,	,	PUNCT
fnp-5848	205	80	han	han	PROPN
fnp-5848	205	81	,	,	PUNCT
fnp-5848	205	82	x.	x.	NOUN
fnp-5848	205	83	,	,	PUNCT
fnp-5848	205	84	crary	crary	PROPN
fnp-5848	205	85	,	,	PUNCT
fnp-5848	205	86	j.	j.	PROPN
fnp-5848	205	87	f.	f.	PROPN
fnp-5848	205	88	,	,	PUNCT
fnp-5848	205	89	…	…	PUNCT
fnp-5848	205	90	stein	stein	PROPN
fnp-5848	205	91	,	,	PUNCT
fnp-5848	205	92	t.	t.	PROPN
fnp-5848	205	93	d.	d.	PROPN
fnp-5848	205	94	(	(	PUNCT
fnp-5848	205	95	2023	2023	NUM
fnp-5848	205	96	)	)	PUNCT
fnp-5848	205	97	.	.	PUNCT
fnp-5848	206	1	repetitive	repetitive	ADJ
fnp-5848	206	2	head	head	NOUN
fnp-5848	206	3	impacts	impact	NOUN
fnp-5848	206	4	and	and	CCONJ
fnp-5848	206	5	chronic	chronic	ADJ
fnp-5848	206	6	traumatic	traumatic	ADJ
fnp-5848	206	7	encephalopathy	encephalopathy	NOUN
fnp-5848	206	8	are	be	AUX
fnp-5848	206	9	associated	associate	VERB
fnp-5848	206	10	with	with	ADP
fnp-5848	206	11	tdp-43	tdp-43	NOUN
fnp-5848	206	12	inclusions	inclusion	NOUN
fnp-5848	206	13	and	and	CCONJ
fnp-5848	206	14	hippocampal	hippocampal	ADJ
fnp-5848	206	15	sclerosis	sclerosis	NOUN
fnp-5848	206	16	.	.	PUNCT
fnp-5848	207	1	acta	acta	PROPN
fnp-5848	207	2	neuropathologica	neuropathologica	PROPN
fnp-5848	207	3	,	,	PUNCT
fnp-5848	207	4	145(4	145(4	NUM
fnp-5848	207	5	)	)	PUNCT
fnp-5848	207	6	,	,	PUNCT
fnp-5848	207	7	395–408	395–408	NUM
fnp-5848	207	8	.	.	PUNCT
fnp-5848	208	1	https://doi.org/10.1007/s00401-023-02539-3	https://doi.org/10.1007/s00401-023-02539-3	PROPN
fnp-5848	208	2	https://doi.org/10.17879/freeneuropathology-2024https://doi.org/10.1038/s41586-023-05788-0	https://doi.org/10.17879/freeneuropathology-2024https://doi.org/10.1038/s41586-023-05788-0	PROPN
fnp-5848	208	3	https://doi.org/10.1002/alz.13357	https://doi.org/10.1002/alz.13357	PROPN
fnp-5848	209	1	https://doi.org/10.1001/jamaneurol.2022.5416	https://doi.org/10.1001/jamaneurol.2022.5416	PROPN
fnp-5848	209	2	https://doi.org/10.1016/j.neuron.2022.12.029	https://doi.org/10.1016/j.neuron.2022.12.029	PROPN
fnp-5848	209	3	https://doi.org/10.1007/s00401-023-02636-3	https://doi.org/10.1007/s00401-023-02636-3	NUM
fnp-5848	209	4	https://doi.org/10.1001/jamaneurol.2023.2907	https://doi.org/10.1001/jamaneurol.2023.2907	PROPN
fnp-5848	209	5	https://doi.org/10.1007/s00401-023-02539-3	https://doi.org/10.1007/s00401-023-02539-3	NUM
fnp-5848	209	6	free	free	ADJ
fnp-5848	209	7	neuropathology	neuropathology	NOUN
fnp-5848	209	8	5:31	5:31	NUM
fnp-5848	209	9	(	(	PUNCT
fnp-5848	209	10	2024	2024	NUM
fnp-5848	209	11	)	)	PUNCT
fnp-5848	210	1	john	john	PROPN
fnp-5848	210	2	f.	f.	PROPN
fnp-5848	210	3	crary	crary	PROPN
fnp-5848	210	4	doi	doi	PROPN
fnp-5848	210	5	:	:	PUNCT
fnp-5848	210	6	https://doi.org/10.17879/freeneuropathology-2024-5848	https://doi.org/10.17879/freeneuropathology-2024-5848	NOUN
fnp-5848	210	7	page	page	NOUN
fnp-5848	210	8	12	12	NUM
fnp-5848	210	9	of	of	ADP
fnp-5848	210	10	12	12	NUM
fnp-5848	210	11	pomeshchik	pomeshchik	NOUN
fnp-5848	210	12	,	,	PUNCT
fnp-5848	210	13	y.	y.	PROPN
fnp-5848	210	14	,	,	PUNCT
fnp-5848	210	15	velasquez	velasquez	PROPN
fnp-5848	210	16	,	,	PUNCT
fnp-5848	210	17	e.	e.	PROPN
fnp-5848	210	18	,	,	PUNCT
fnp-5848	210	19	gil	gil	PROPN
fnp-5848	210	20	,	,	PUNCT
fnp-5848	210	21	j.	j.	PROPN
fnp-5848	210	22	,	,	PUNCT
fnp-5848	210	23	klementieva	klementieva	PROPN
fnp-5848	210	24	,	,	PUNCT
fnp-5848	210	25	o.	o.	NOUN
fnp-5848	210	26	,	,	PUNCT
fnp-5848	210	27	gidlöf	gidlöf	NOUN
fnp-5848	210	28	,	,	PUNCT
fnp-5848	210	29	r.	r.	PROPN
fnp-5848	210	30	,	,	PUNCT
fnp-5848	210	31	sydoff	sydoff	NOUN
fnp-5848	210	32	,	,	PUNCT
fnp-5848	210	33	m.	m.	NOUN
fnp-5848	210	34	,	,	PUNCT
fnp-5848	210	35	bagnoli	bagnoli	NOUN
fnp-5848	210	36	,	,	PUNCT
fnp-5848	210	37	s.	s.	PROPN
fnp-5848	210	38	,	,	PUNCT
fnp-5848	210	39	nacmias	nacmias	PROPN
fnp-5848	210	40	,	,	PUNCT
fnp-5848	210	41	b.	b.	PROPN
fnp-5848	210	42	,	,	PUNCT
fnp-5848	210	43	sorbi	sorbi	PROPN
fnp-5848	210	44	,	,	PUNCT
fnp-5848	210	45	s.	s.	PROPN
fnp-5848	210	46	,	,	PUNCT
fnp-5848	210	47	westergren	westergren	PROPN
fnp-5848	210	48	-	-	PUNCT
fnp-5848	210	49	thorsson	thorsson	PROPN
fnp-5848	210	50	,	,	PUNCT
fnp-5848	210	51	g.	g.	NOUN
fnp-5848	210	52	,	,	PUNCT
fnp-5848	210	53	gouras	gouras	NOUN
fnp-5848	210	54	,	,	PUNCT
fnp-5848	210	55	g.	g.	PROPN
fnp-5848	210	56	k.	k.	PROPN
fnp-5848	210	57	,	,	PUNCT
fnp-5848	210	58	rezeli	rezeli	PROPN
fnp-5848	210	59	,	,	PUNCT
fnp-5848	210	60	m.	m.	NOUN
fnp-5848	210	61	,	,	PUNCT
fnp-5848	210	62	&	&	CCONJ
fnp-5848	210	63	roybon	roybon	PROPN
fnp-5848	210	64	,	,	PUNCT
fnp-5848	210	65	l.	l.	PROPN
fnp-5848	210	66	(	(	PUNCT
fnp-5848	210	67	2023	2023	NUM
fnp-5848	210	68	)	)	PUNCT
fnp-5848	210	69	.	.	PUNCT
fnp-5848	211	1	proteomic	proteomic	ADJ
fnp-5848	211	2	analysis	analysis	NOUN
fnp-5848	211	3	across	across	ADP
fnp-5848	211	4	patient	patient	ADJ
fnp-5848	211	5	ipsc	ipsc	NOUN
fnp-5848	211	6	-	-	PUNCT
fnp-5848	211	7	based	base	VERB
fnp-5848	211	8	models	model	NOUN
fnp-5848	211	9	and	and	CCONJ
fnp-5848	211	10	human	human	ADJ
fnp-5848	211	11	post	post	ADJ
fnp-5848	211	12	-	-	ADJ
fnp-5848	211	13	mortem	mortem	ADJ
fnp-5848	211	14	hippocampal	hippocampal	ADJ
fnp-5848	211	15	tissue	tissue	NOUN
fnp-5848	211	16	reveals	reveal	VERB
fnp-5848	211	17	early	early	ADJ
fnp-5848	211	18	cellular	cellular	ADJ
fnp-5848	211	19	dysfunction	dysfunction	NOUN
fnp-5848	211	20	and	and	CCONJ
fnp-5848	211	21	progression	progression	NOUN
fnp-5848	211	22	of	of	ADP
fnp-5848	211	23	alzheimer	alzheimer	PROPN
fnp-5848	211	24	’s	’s	PART
fnp-5848	211	25	disease	disease	NOUN
fnp-5848	211	26	pathogenesis	pathogenesis	NOUN
fnp-5848	211	27	.	.	PUNCT
fnp-5848	212	1	acta	acta	PROPN
fnp-5848	212	2	neuropathologica	neuropathologica	PROPN
fnp-5848	212	3	communications	communications	PROPN
fnp-5848	212	4	,	,	PUNCT
fnp-5848	212	5	11(1	11(1	NUM
fnp-5848	212	6	)	)	PUNCT
fnp-5848	212	7	,	,	PUNCT
fnp-5848	212	8	150	150	NUM
fnp-5848	212	9	.	.	PUNCT
fnp-5848	213	1	https://doi.org/10.1186/s40478-023-01649-z	https://doi.org/10.1186/s40478-023-01649-z	PROPN
fnp-5848	213	2	yagita	yagita	PROPN
fnp-5848	213	3	,	,	PUNCT
fnp-5848	213	4	k.	k.	PROPN
fnp-5848	213	5	,	,	PUNCT
fnp-5848	213	6	sadashima	sadashima	PROPN
fnp-5848	213	7	,	,	PUNCT
fnp-5848	213	8	s.	s.	PROPN
fnp-5848	213	9	,	,	PUNCT
fnp-5848	213	10	koyama	koyama	PROPN
fnp-5848	213	11	,	,	PUNCT
fnp-5848	213	12	s.	s.	PROPN
fnp-5848	213	13	,	,	PUNCT
fnp-5848	213	14	noguchi	noguchi	PROPN
fnp-5848	213	15	,	,	PUNCT
fnp-5848	213	16	h.	h.	PROPN
fnp-5848	213	17	,	,	PUNCT
fnp-5848	213	18	hamasaki	hamasaki	PROPN
fnp-5848	213	19	,	,	PUNCT
fnp-5848	213	20	h.	h.	PROPN
fnp-5848	213	21	,	,	PUNCT
fnp-5848	213	22	sasagasako	sasagasako	PROPN
fnp-5848	213	23	,	,	PUNCT
fnp-5848	213	24	n.	n.	NOUN
fnp-5848	213	25	,	,	PUNCT
fnp-5848	213	26	&	&	CCONJ
fnp-5848	213	27	honda	honda	PROPN
fnp-5848	213	28	,	,	PUNCT
fnp-5848	213	29	h.	h.	PROPN
fnp-5848	213	30	(	(	PUNCT
fnp-5848	213	31	2024	2024	NUM
fnp-5848	213	32	)	)	PUNCT
fnp-5848	213	33	.	.	PUNCT
fnp-5848	214	1	ribosomal	ribosomal	NOUN
fnp-5848	214	2	protein	protein	NOUN
fnp-5848	214	3	sa	sa	PROPN
fnp-5848	214	4	is	be	AUX
fnp-5848	214	5	a	a	DET
fnp-5848	214	6	common	common	ADJ
fnp-5848	214	7	component	component	NOUN
fnp-5848	214	8	of	of	ADP
fnp-5848	214	9	neuronal	neuronal	ADJ
fnp-5848	214	10	intranuclear	intranuclear	NOUN
fnp-5848	214	11	inclusions	inclusion	NOUN
fnp-5848	214	12	in	in	ADP
fnp-5848	214	13	polyglutamine	polyglutamine	NOUN
fnp-5848	214	14	diseases	disease	NOUN
fnp-5848	214	15	and	and	CCONJ
fnp-5848	214	16	marinesco	marinesco	ADJ
fnp-5848	214	17	bodies	body	NOUN
fnp-5848	214	18	.	.	PUNCT
fnp-5848	215	1	neuropathology	neuropathology	NOUN
fnp-5848	215	2	:	:	PUNCT
fnp-5848	215	3	official	official	ADJ
fnp-5848	215	4	journal	journal	NOUN
fnp-5848	215	5	of	of	ADP
fnp-5848	215	6	the	the	DET
fnp-5848	215	7	japanese	japanese	ADJ
fnp-5848	215	8	society	society	NOUN
fnp-5848	215	9	of	of	ADP
fnp-5848	215	10	neuropathology	neuropathology	NOUN
fnp-5848	215	11	,	,	PUNCT
fnp-5848	215	12	44(1	44(1	PROPN
fnp-5848	215	13	)	)	PUNCT
fnp-5848	215	14	,	,	PUNCT
fnp-5848	215	15	31–40	31–40	NUM
fnp-5848	215	16	.	.	PUNCT
fnp-5848	216	1	https://doi.org/10.1111/neup.12927	https://doi.org/10.1111/neup.12927	X
fnp-5848	217	1	yang	yang	PROPN
fnp-5848	217	2	,	,	PUNCT
fnp-5848	217	3	h.-s	h.-s	PROPN
fnp-5848	217	4	.	.	PUNCT
fnp-5848	217	5	,	,	PUNCT
fnp-5848	217	6	teng	teng	PROPN
fnp-5848	217	7	,	,	PUNCT
fnp-5848	217	8	l.	l.	PROPN
fnp-5848	217	9	,	,	PUNCT
fnp-5848	217	10	kang	kang	PROPN
fnp-5848	217	11	,	,	PUNCT
fnp-5848	217	12	d.	d.	PROPN
fnp-5848	217	13	,	,	PUNCT
fnp-5848	217	14	menon	menon	PROPN
fnp-5848	217	15	,	,	PUNCT
fnp-5848	217	16	v.	v.	PROPN
fnp-5848	217	17	,	,	PUNCT
fnp-5848	217	18	ge	ge	PROPN
fnp-5848	217	19	,	,	PUNCT
fnp-5848	217	20	t.	t.	PROPN
fnp-5848	217	21	,	,	PUNCT
fnp-5848	217	22	finucane	finucane	NOUN
fnp-5848	217	23	,	,	PUNCT
fnp-5848	217	24	h.	h.	PROPN
fnp-5848	217	25	k.	k.	PROPN
fnp-5848	217	26	,	,	PUNCT
fnp-5848	217	27	schultz	schultz	PROPN
fnp-5848	217	28	,	,	PUNCT
fnp-5848	217	29	a.	a.	NOUN
fnp-5848	217	30	p.	p.	NOUN
fnp-5848	217	31	,	,	PUNCT
fnp-5848	217	32	properzi	properzi	NOUN
fnp-5848	217	33	,	,	PUNCT
fnp-5848	217	34	m.	m.	NOUN
fnp-5848	217	35	,	,	PUNCT
fnp-5848	217	36	klein	klein	PROPN
fnp-5848	217	37	,	,	PUNCT
fnp-5848	217	38	h.-u	h.-u	PROPN
fnp-5848	217	39	.	.	PUNCT
fnp-5848	217	40	,	,	PUNCT
fnp-5848	217	41	chibnik	chibnik	PROPN
fnp-5848	217	42	,	,	PUNCT
fnp-5848	217	43	l.	l.	PROPN
fnp-5848	217	44	b.	b.	PROPN
fnp-5848	217	45	,	,	PUNCT
fnp-5848	217	46	schneider	schneider	PROPN
fnp-5848	217	47	,	,	PUNCT
fnp-5848	217	48	j.	j.	PROPN
fnp-5848	217	49	a.	a.	PROPN
fnp-5848	217	50	,	,	PUNCT
fnp-5848	217	51	bennett	bennett	PROPN
fnp-5848	217	52	,	,	PUNCT
fnp-5848	217	53	d.	d.	PROPN
fnp-5848	217	54	a.	a.	PROPN
fnp-5848	217	55	,	,	PUNCT
fnp-5848	217	56	hohman	hohman	NOUN
fnp-5848	217	57	,	,	PUNCT
fnp-5848	217	58	t.	t.	PROPN
fnp-5848	217	59	j.	j.	PROPN
fnp-5848	217	60	,	,	PUNCT
fnp-5848	217	61	mayeux	mayeux	PROPN
fnp-5848	217	62	,	,	PUNCT
fnp-5848	217	63	r.	r.	PROPN
fnp-5848	217	64	p.	p.	PROPN
fnp-5848	217	65	,	,	PUNCT
fnp-5848	217	66	johnson	johnson	PROPN
fnp-5848	217	67	,	,	PUNCT
fnp-5848	217	68	k.	k.	PROPN
fnp-5848	217	69	a.	a.	PROPN
fnp-5848	217	70	,	,	PUNCT
fnp-5848	217	71	de	de	X
fnp-5848	217	72	jager	jager	PROPN
fnp-5848	217	73	,	,	PUNCT
fnp-5848	217	74	p.	p.	PROPN
fnp-5848	217	75	l.	l.	PROPN
fnp-5848	217	76	,	,	PUNCT
fnp-5848	217	77	&	&	CCONJ
fnp-5848	217	78	sperling	sperling	PROPN
fnp-5848	217	79	,	,	PUNCT
fnp-5848	217	80	r.	r.	PROPN
fnp-5848	217	81	a.	a.	PROPN
fnp-5848	217	82	(	(	PUNCT
fnp-5848	217	83	2023	2023	NUM
fnp-5848	217	84	)	)	PUNCT
fnp-5848	217	85	.	.	PUNCT
fnp-5848	218	1	cell	cell	NOUN
fnp-5848	218	2	-	-	PUNCT
fnp-5848	218	3	type	type	NOUN
fnp-5848	218	4	-	-	PUNCT
fnp-5848	218	5	specific	specific	ADJ
fnp-5848	218	6	alzheimer	alzheimer	NOUN
fnp-5848	218	7	’s	’s	PART
fnp-5848	218	8	disease	disease	NOUN
fnp-5848	218	9	polygenic	polygenic	ADJ
fnp-5848	218	10	risk	risk	NOUN
fnp-5848	218	11	scores	score	NOUN
fnp-5848	218	12	are	be	AUX
fnp-5848	218	13	associated	associate	VERB
fnp-5848	218	14	with	with	ADP
fnp-5848	218	15	distinct	distinct	ADJ
fnp-5848	218	16	disease	disease	NOUN
fnp-5848	218	17	processes	process	NOUN
fnp-5848	218	18	in	in	ADP
fnp-5848	218	19	alzheimer	alzheimer	PROPN
fnp-5848	218	20	’s	’s	PART
fnp-5848	218	21	disease	disease	NOUN
fnp-5848	218	22	.	.	PUNCT
fnp-5848	219	1	nature	nature	NOUN
fnp-5848	219	2	communications	communication	NOUN
fnp-5848	219	3	,	,	PUNCT
fnp-5848	219	4	14(1	14(1	NUM
fnp-5848	219	5	)	)	PUNCT
fnp-5848	219	6	,	,	PUNCT
fnp-5848	219	7	7659	7659	NUM
fnp-5848	219	8	.	.	PUNCT
fnp-5848	220	1	https://doi.org/10.1038/s41467-023-43132-2	https://doi.org/10.1038/s41467-023-43132-2	PROPN
fnp-5848	220	2	yonenobu	yonenobu	PROPN
fnp-5848	220	3	,	,	PUNCT
fnp-5848	220	4	y.	y.	PROPN
fnp-5848	220	5	,	,	PUNCT
fnp-5848	220	6	beck	beck	PROPN
fnp-5848	220	7	,	,	PUNCT
fnp-5848	220	8	g.	g.	PROPN
fnp-5848	220	9	,	,	PUNCT
fnp-5848	220	10	kido	kido	NOUN
fnp-5848	220	11	,	,	PUNCT
fnp-5848	220	12	k.	k.	PROPN
fnp-5848	220	13	,	,	PUNCT
fnp-5848	220	14	maeda	maeda	PROPN
fnp-5848	220	15	,	,	PUNCT
fnp-5848	220	16	n.	n.	PROPN
fnp-5848	220	17	,	,	PUNCT
fnp-5848	220	18	yamashita	yamashita	PROPN
fnp-5848	220	19	,	,	PUNCT
fnp-5848	220	20	r.	r.	PROPN
fnp-5848	220	21	,	,	PUNCT
fnp-5848	220	22	inoue	inoue	PROPN
fnp-5848	220	23	,	,	PUNCT
fnp-5848	220	24	k.	k.	PROPN
fnp-5848	220	25	,	,	PUNCT
fnp-5848	220	26	saito	saito	PROPN
fnp-5848	220	27	,	,	PUNCT
fnp-5848	220	28	y.	y.	PROPN
fnp-5848	220	29	,	,	PUNCT
fnp-5848	220	30	hasegawa	hasegawa	PROPN
fnp-5848	220	31	,	,	PUNCT
fnp-5848	220	32	m.	m.	NOUN
fnp-5848	220	33	,	,	PUNCT
fnp-5848	220	34	ito	ito	PROPN
fnp-5848	220	35	,	,	PUNCT
fnp-5848	220	36	h.	h.	PROPN
fnp-5848	220	37	,	,	PUNCT
fnp-5848	220	38	hasegawa	hasegawa	PROPN
fnp-5848	220	39	,	,	PUNCT
fnp-5848	220	40	k.	k.	PROPN
fnp-5848	220	41	,	,	PUNCT
fnp-5848	220	42	morii	morii	PROPN
fnp-5848	220	43	,	,	PUNCT
fnp-5848	220	44	e.	e.	PROPN
fnp-5848	220	45	,	,	PUNCT
fnp-5848	220	46	iwaki	iwaki	NOUN
fnp-5848	220	47	,	,	PUNCT
fnp-5848	220	48	t.	t.	NOUN
fnp-5848	220	49	,	,	PUNCT
fnp-5848	220	50	murayama	murayama	PROPN
fnp-5848	220	51	,	,	PUNCT
fnp-5848	220	52	s.	s.	PROPN
fnp-5848	220	53	,	,	PUNCT
fnp-5848	220	54	&	&	CCONJ
fnp-5848	220	55	mochizuki	mochizuki	PROPN
fnp-5848	220	56	,	,	PUNCT
fnp-5848	220	57	h.	h.	PROPN
fnp-5848	220	58	(	(	PUNCT
fnp-5848	220	59	2023	2023	NUM
fnp-5848	220	60	)	)	PUNCT
fnp-5848	220	61	.	.	PUNCT
fnp-5848	221	1	neuropathology	neuropathology	NOUN
fnp-5848	221	2	of	of	ADP
fnp-5848	221	3	spinocerebellar	spinocerebellar	ADJ
fnp-5848	221	4	ataxia	ataxia	NOUN
fnp-5848	221	5	type	type	NOUN
fnp-5848	221	6	8	8	NUM
fnp-5848	221	7	:	:	PUNCT
fnp-5848	221	8	common	common	ADJ
fnp-5848	221	9	features	feature	NOUN
fnp-5848	221	10	and	and	CCONJ
fnp-5848	221	11	unique	unique	ADJ
fnp-5848	221	12	tauopathy	tauopathy	NOUN
fnp-5848	221	13	.	.	PUNCT
fnp-5848	222	1	neuropathology	neuropathology	NOUN
fnp-5848	222	2	:	:	PUNCT
fnp-5848	222	3	official	official	ADJ
fnp-5848	222	4	journal	journal	NOUN
fnp-5848	222	5	of	of	ADP
fnp-5848	222	6	the	the	DET
fnp-5848	222	7	japanese	japanese	ADJ
fnp-5848	222	8	society	society	NOUN
fnp-5848	222	9	of	of	ADP
fnp-5848	222	10	neuropathology	neuropathology	NOUN
fnp-5848	222	11	,	,	PUNCT
fnp-5848	222	12	43(5	43(5	NUM
fnp-5848	222	13	)	)	PUNCT
fnp-5848	222	14	,	,	PUNCT
fnp-5848	222	15	351–361	351–361	NUM
fnp-5848	222	16	.	.	PUNCT
fnp-5848	222	17	https://doi.org/10.1111/neup.12894	https://doi.org/10.1111/neup.12894	ADJ
fnp-5848	222	18	https://doi.org/10.17879/freeneuropathology-2024https://doi.org/10.1186/s40478-023-01649-z	https://doi.org/10.17879/freeneuropathology-2024https://doi.org/10.1186/s40478-023-01649-z	PROPN
fnp-5848	222	19	https://doi.org/10.1111/neup.12927	https://doi.org/10.1111/neup.12927	PROPN
fnp-5848	222	20	https://doi.org/10.1038/s41467-023-43132-2	https://doi.org/10.1038/s41467-023-43132-2	PROPN
fnp-5848	222	21	https://doi.org/10.1111/neup.12894	https://doi.org/10.1111/neup.12894	ADJ
fnp-5848	222	22	rewiew	rewiew	NOUN
fnp-5848	222	23	1	1	NUM
fnp-5848	222	24	.	.	PUNCT
fnp-5848	222	25	 	 	SPACE
fnp-5848	222	26	chronic	chronic	ADJ
fnp-5848	222	27	traumatic	traumatic	ADJ
fnp-5848	222	28	encephalopathy	encephalopathy	NOUN
fnp-5848	222	29	in	in	ADP
fnp-5848	222	30	young	young	ADJ
fnp-5848	222	31	athletes	athlete	NOUN
fnp-5848	222	32	’	'	PUNCT
fnp-5848	222	33	post	post	ADJ
fnp-5848	222	34	-	-	ADJ
fnp-5848	222	35	repetitive	repetitive	ADJ
fnp-5848	222	36	head	head	NOUN
fnp-5848	222	37	impacts	impact	NOUN
fnp-5848	222	38	2	2	NUM
fnp-5848	222	39	.	.	PUNCT
fnp-5848	222	40	 	 	SPACE
fnp-5848	222	41	hippocampal	hippocampal	ADJ
fnp-5848	222	42	sclerosis	sclerosis	NOUN
fnp-5848	222	43	with	with	ADP
fnp-5848	222	44	tdp-43	tdp-43	NOUN
fnp-5848	222	45	inclusions	inclusion	NOUN
fnp-5848	222	46	following	follow	VERB
fnp-5848	222	47	repetitive	repetitive	ADJ
fnp-5848	222	48	head	head	NOUN
fnp-5848	222	49	impacts	impact	VERB
fnp-5848	222	50	3	3	NUM
fnp-5848	222	51	.	.	PUNCT
fnp-5848	222	52	 	 	SPACE
fnp-5848	222	53	longitudinal	longitudinal	ADJ
fnp-5848	222	54	motor	motor	NOUN
fnp-5848	222	55	decline	decline	NOUN
fnp-5848	222	56	in	in	ADP
fnp-5848	222	57	diffuse	diffuse	PROPN
fnp-5848	222	58	lewy	lewy	ADJ
fnp-5848	222	59	body	body	NOUN
fnp-5848	222	60	disease	disease	NOUN
fnp-5848	222	61	,	,	PUNCT
fnp-5848	222	62	parkinson	parkinson	NOUN
fnp-5848	222	63	’s	’s	PART
fnp-5848	222	64	disease	disease	NOUN
fnp-5848	222	65	with	with	ADP
fnp-5848	222	66	dementia	dementia	NOUN
fnp-5848	222	67	,	,	PUNCT
fnp-5848	222	68	and	and	CCONJ
fnp-5848	222	69	alzheimer	alzheimer	PROPN
fnp-5848	222	70	’s	’s	PART
fnp-5848	222	71	disease	disease	NOUN
fnp-5848	222	72	4	4	NUM
fnp-5848	222	73	.	.	PUNCT
fnp-5848	222	74	 	 	SPACE
fnp-5848	222	75	cell	cell	NOUN
fnp-5848	222	76	-	-	PUNCT
fnp-5848	222	77	type	type	NOUN
fnp-5848	222	78	-	-	PUNCT
fnp-5848	222	79	specific	specific	ADJ
fnp-5848	222	80	alzheimer	alzheimer	NOUN
fnp-5848	222	81	’s	’s	PART
fnp-5848	222	82	polygenic	polygenic	ADJ
fnp-5848	222	83	risk	risk	NOUN
fnp-5848	222	84	scores	score	VERB
fnp-5848	222	85	5	5	NUM
fnp-5848	222	86	.	.	PUNCT
fnp-5848	222	87	 	 	SPACE
fnp-5848	222	88	histological	histological	ADJ
fnp-5848	222	89	brain	brain	NOUN
fnp-5848	222	90	age	age	NOUN
fnp-5848	222	91	acceleration	acceleration	NOUN
fnp-5848	222	92	using	use	VERB
fnp-5848	222	93	digital	digital	ADJ
fnp-5848	222	94	neuropathology	neuropathology	NOUN
fnp-5848	222	95	and	and	CCONJ
fnp-5848	222	96	artificial	artificial	ADJ
fnp-5848	222	97	intelligence	intelligence	NOUN
fnp-5848	222	98	6	6	NUM
fnp-5848	222	99	.	.	PUNCT
fnp-5848	222	100	 	 	SPACE
fnp-5848	222	101	decline	decline	NOUN
fnp-5848	222	102	in	in	ADP
fnp-5848	222	103	cerebrovascular	cerebrovascular	ADJ
fnp-5848	222	104	pathologies	pathology	NOUN
fnp-5848	222	105	over	over	ADP
fnp-5848	222	106	25	25	NUM
fnp-5848	222	107	years	year	NOUN
fnp-5848	222	108	7	7	NUM
fnp-5848	222	109	.	.	PUNCT
fnp-5848	222	110	 	 	SPACE
fnp-5848	222	111	microglia	microglia	PROPN
fnp-5848	222	112	-	-	PUNCT
fnp-5848	222	113	t	t	NOUN
fnp-5848	222	114	cell	cell	NOUN
fnp-5848	222	115	interaction	interaction	NOUN
fnp-5848	222	116	in	in	ADP
fnp-5848	222	117	alzheimer	alzheimer	PROPN
fnp-5848	222	118	’s	’s	PART
fnp-5848	222	119	disease	disease	NOUN
fnp-5848	222	120	and	and	CCONJ
fnp-5848	222	121	tauopathy	tauopathy	ADJ
fnp-5848	222	122	8	8	NUM
fnp-5848	222	123	.	.	PUNCT
fnp-5848	222	124	 	 	SPACE
fnp-5848	222	125	viral	viral	ADJ
fnp-5848	222	126	exposures	exposure	NOUN
fnp-5848	222	127	linked	link	VERB
fnp-5848	222	128	to	to	ADP
fnp-5848	222	129	neurodegeneration	neurodegeneration	NOUN
fnp-5848	222	130	9	9	NUM
fnp-5848	222	131	.	.	PUNCT
fnp-5848	222	132	 	 	SPACE
fnp-5848	223	1	polyglutamine	polyglutamine	NOUN
fnp-5848	223	2	(	(	PUNCT
fnp-5848	223	3	polyq	polyq	NOUN
fnp-5848	223	4	)	)	PUNCT
fnp-5848	223	5	diseases	disease	NOUN
fnp-5848	223	6	:	:	PUNCT
fnp-5848	223	7	ribosomal	ribosomal	NOUN
fnp-5848	223	8	proteins	protein	NOUN
fnp-5848	223	9	and	and	CCONJ
fnp-5848	223	10	tauopathy	tauopathy	NOUN
fnp-5848	223	11	funding	fund	VERB
fnp-5848	223	12	statement	statement	NOUN
fnp-5848	223	13	conflict	conflict	NOUN
fnp-5848	223	14	of	of	ADP
fnp-5848	223	15	interest	interest	NOUN
fnp-5848	223	16	disclosure	disclosure	NOUN
fnp-5848	223	17	statement	statement	NOUN
fnp-5848	223	18	references	reference	NOUN