id sid tid token lemma pos fnp-5983 1 1 a a DET fnp-5983 1 2 novel novel ADJ fnp-5983 1 3 fus::bend2 fus::bend2 ADJ fnp-5983 1 4 fusion fusion NOUN fnp-5983 1 5 expanding expand VERB fnp-5983 1 6 the the DET fnp-5983 1 7 molecular molecular ADJ fnp-5983 1 8 spectrum spectrum NOUN fnp-5983 1 9 of of ADP fnp-5983 1 10 astroblastomas astroblastoma NOUN fnp-5983 1 11 feel feel VERB fnp-5983 1 12 free free ADJ fnp-5983 1 13 to to PART fnp-5983 1 14 add add VERB fnp-5983 1 15 comments comment NOUN fnp-5983 1 16 by by ADP fnp-5983 1 17 clicking click VERB fnp-5983 1 18 these these DET fnp-5983 1 19 icons icon NOUN fnp-5983 1 20 on on ADP fnp-5983 1 21 the the DET fnp-5983 1 22 sidebar sidebar NOUN fnp-5983 1 23 free free ADJ fnp-5983 1 24 neuropathology neuropathology NOUN fnp-5983 1 25 5:34 5:34 NUM fnp-5983 1 26 ( ( PUNCT fnp-5983 1 27 2024 2024 NUM fnp-5983 1 28 ) ) PUNCT fnp-5983 1 29 letter letter NOUN fnp-5983 1 30 a a DET fnp-5983 1 31 novel novel ADJ fnp-5983 1 32 fus::bend2 fus::bend2 ADJ fnp-5983 1 33 fusion fusion NOUN fnp-5983 1 34 expanding expand VERB fnp-5983 1 35 the the DET fnp-5983 1 36 molecular molecular ADJ fnp-5983 1 37 spectrum spectrum NOUN fnp-5983 1 38 of of ADP fnp-5983 1 39 astroblastomas astroblastomas PROPN fnp-5983 1 40 arnault arnault VERB fnp-5983 1 41 tauziède tauziède VERB fnp-5983 1 42 - - PUNCT fnp-5983 1 43 espariat1,2 espariat1,2 PROPN fnp-5983 1 44 , , PUNCT fnp-5983 1 45 benjamin benjamin PROPN fnp-5983 1 46 bonhomme3 bonhomme3 PROPN fnp-5983 1 47 , , PUNCT fnp-5983 1 48 nathalène nathalène PROPN fnp-5983 1 49 truffaux3 truffaux3 PROPN fnp-5983 1 50 , , PUNCT fnp-5983 1 51 volodia volodia NOUN fnp-5983 1 52 dangouloff dangouloff NOUN fnp-5983 1 53 - - PUNCT fnp-5983 1 54 ros4 ros4 NOUN fnp-5983 1 55 , , PUNCT fnp-5983 1 56 nathalie nathalie PROPN fnp-5983 1 57 boddaert4 boddaert4 PROPN fnp-5983 1 58 , , PUNCT fnp-5983 1 59 kévin kévin NOUN fnp-5983 1 60 beccaria5 beccaria5 NOUN fnp-5983 1 61 , , PUNCT fnp-5983 1 62 lauren lauren PROPN fnp-5983 1 63 hasty1 hasty1 PROPN fnp-5983 1 64 , , PUNCT fnp-5983 1 65 alice alice PROPN fnp-5983 1 66 métais1,2 métais1,2 PROPN fnp-5983 1 67 , , PUNCT fnp-5983 1 68 pascale pascale PROPN fnp-5983 1 69 varlet1,2 varlet1,2 PROPN fnp-5983 1 70 department department NOUN fnp-5983 1 71 of of ADP fnp-5983 1 72 neuropathology neuropathology NOUN fnp-5983 1 73 , , PUNCT fnp-5983 1 74 ghu ghu PROPN fnp-5983 1 75 paris paris PROPN fnp-5983 1 76 psychiatry psychiatry NOUN fnp-5983 1 77 and and CCONJ fnp-5983 1 78 neuroscience neuroscience NOUN fnp-5983 1 79 , , PUNCT fnp-5983 1 80 sainte sainte PROPN fnp-5983 1 81 - - PUNCT fnp-5983 1 82 anne anne PROPN fnp-5983 1 83 hospital hospital PROPN fnp-5983 1 84 , , PUNCT fnp-5983 1 85 paris paris PROPN fnp-5983 1 86 , , PUNCT fnp-5983 1 87 france france PROPN fnp-5983 1 88 institut institut PROPN fnp-5983 1 89 de de PROPN fnp-5983 1 90 psychiatrie psychiatrie PROPN fnp-5983 1 91 et et PROPN fnp-5983 1 92 neurosciences neurosciences PROPN fnp-5983 1 93 de de X fnp-5983 1 94 paris paris PROPN fnp-5983 1 95 ( ( PUNCT fnp-5983 1 96 ipnp ipnp PROPN fnp-5983 1 97 ) ) PUNCT fnp-5983 1 98 , , PUNCT fnp-5983 1 99 umr umr PROPN fnp-5983 1 100 s1266 s1266 PROPN fnp-5983 1 101 , , PUNCT fnp-5983 1 102 inserm inserm NOUN fnp-5983 1 103 , , PUNCT fnp-5983 1 104 ima ima PROPN fnp-5983 1 105 - - PUNCT fnp-5983 1 106 brain brain PROPN fnp-5983 1 107 , , PUNCT fnp-5983 1 108 paris paris PROPN fnp-5983 1 109 , , PUNCT fnp-5983 1 110 france france PROPN fnp-5983 1 111 department department PROPN fnp-5983 1 112 of of ADP fnp-5983 1 113 biopathology biopathology PROPN fnp-5983 1 114 , , PUNCT fnp-5983 1 115 institut institut PROPN fnp-5983 1 116 bergonié bergonié PROPN fnp-5983 1 117 , , PUNCT fnp-5983 1 118 bordeaux bordeaux NOUN fnp-5983 1 119 , , PUNCT fnp-5983 1 120 france france PROPN fnp-5983 1 121 pediatric pediatric ADJ fnp-5983 1 122 radiology radiology NOUN fnp-5983 1 123 department department PROPN fnp-5983 1 124 , , PUNCT fnp-5983 1 125 hôpital hôpital PROPN fnp-5983 1 126 necker necker PROPN fnp-5983 1 127 enfants enfants X fnp-5983 1 128 malades malades PROPN fnp-5983 1 129 , , PUNCT fnp-5983 1 130 ap ap PROPN fnp-5983 1 131 - - PUNCT fnp-5983 1 132 hp hp PROPN fnp-5983 1 133 , , PUNCT fnp-5983 1 134 university university PROPN fnp-5983 1 135 de de X fnp-5983 1 136 paris paris PROPN fnp-5983 1 137 , , PUNCT fnp-5983 1 138 paris paris PROPN fnp-5983 1 139 , , PUNCT fnp-5983 1 140 france france PROPN fnp-5983 1 141 department department PROPN fnp-5983 1 142 of of ADP fnp-5983 1 143 pediatric pediatric ADJ fnp-5983 1 144 neurosurgery neurosurgery NOUN fnp-5983 1 145 , , PUNCT fnp-5983 1 146 necker necker NOUN fnp-5983 1 147 hospital hospital NOUN fnp-5983 1 148 , , PUNCT fnp-5983 1 149 aphp aphp VERB fnp-5983 1 150 , , PUNCT fnp-5983 1 151 université université PROPN fnp-5983 1 152 paris paris PROPN fnp-5983 1 153 descartes descartes PROPN fnp-5983 1 154 , , PUNCT fnp-5983 1 155 sorbonne sorbonne PROPN fnp-5983 1 156 paris paris PROPN fnp-5983 1 157 cité cité PROPN fnp-5983 1 158 , , PUNCT fnp-5983 1 159 paris paris PROPN fnp-5983 1 160 , , PUNCT fnp-5983 1 161 france france PROPN fnp-5983 1 162 corresponding corresponding ADJ fnp-5983 1 163 author author NOUN fnp-5983 1 164 : : PUNCT fnp-5983 1 165 arnault arnault VERB fnp-5983 1 166 tauziède tauziède VERB fnp-5983 1 167 - - PUNCT fnp-5983 1 168 espariat espariat NOUN fnp-5983 1 169 · · PUNCT fnp-5983 1 170 department department NOUN fnp-5983 1 171 of of ADP fnp-5983 1 172 neuropathology neuropathology NOUN fnp-5983 1 173 · · PUNCT fnp-5983 1 174 sainte sainte PROPN fnp-5983 1 175 - - PUNCT fnp-5983 1 176 anne anne PROPN fnp-5983 1 177 hospital hospital PROPN fnp-5983 1 178 · · PUNCT fnp-5983 1 179 1 1 NUM fnp-5983 1 180 , , PUNCT fnp-5983 1 181 rue rue NOUN fnp-5983 1 182 cabanis cabani NOUN fnp-5983 1 183 , , PUNCT fnp-5983 1 184 75014 75014 NUM fnp-5983 1 185 · · PUNCT fnp-5983 1 186 paris paris PROPN fnp-5983 1 187 · · PUNCT fnp-5983 1 188 france france PROPN fnp-5983 1 189 a.tauziede-espariat@ghu-paris.fr a.tauziede-espariat@ghu-paris.fr VERB fnp-5983 1 190 additional additional ADJ fnp-5983 1 191 resources resource NOUN fnp-5983 1 192 and and CCONJ fnp-5983 1 193 electronic electronic ADJ fnp-5983 1 194 supplementary supplementary ADJ fnp-5983 1 195 material material NOUN fnp-5983 1 196 : : PUNCT fnp-5983 1 197 supplementary supplementary ADJ fnp-5983 1 198 material material NOUN fnp-5983 1 199 submitted submit VERB fnp-5983 1 200 : : PUNCT fnp-5983 1 201 23 23 NUM fnp-5983 1 202 october october NOUN fnp-5983 1 203 2024 2024 NUM fnp-5983 1 204 accepted accept VERB fnp-5983 1 205 : : PUNCT fnp-5983 1 206 21 21 NUM fnp-5983 1 207 november november PROPN fnp-5983 1 208 2024 2024 NUM fnp-5983 1 209 copyedited copyedit VERB fnp-5983 1 210 by by ADP fnp-5983 1 211 : : PUNCT fnp-5983 1 212 shino shino PROPN fnp-5983 1 213 magaki magaki PROPN fnp-5983 1 214 published publish VERB fnp-5983 1 215 : : PUNCT fnp-5983 1 216 10 10 NUM fnp-5983 1 217 december december PROPN fnp-5983 1 218 2024 2024 NUM fnp-5983 1 219 https://doi.org/10.17879/freeneuropathology-2024-5983 https://doi.org/10.17879/freeneuropathology-2024-5983 PROPN fnp-5983 1 220 keywords keyword NOUN fnp-5983 1 221 : : PUNCT fnp-5983 1 222 fus fus PROPN fnp-5983 1 223 , , PUNCT fnp-5983 1 224 bend2 bend2 PROPN fnp-5983 1 225 , , PUNCT fnp-5983 1 226 astroblastoma astroblastoma NOUN fnp-5983 1 227 introduction introduction NOUN fnp-5983 1 228 the the DET fnp-5983 1 229 name name NOUN fnp-5983 1 230 astroblastoma astroblastoma NOUN fnp-5983 1 231 was be AUX fnp-5983 1 232 modified modify VERB fnp-5983 1 233 to to PART fnp-5983 1 234 include include VERB fnp-5983 1 235 “ " PUNCT fnp-5983 1 236 mn1 mn1 NOUN fnp-5983 1 237 - - PUNCT fnp-5983 1 238 altered alter VERB fnp-5983 1 239 ” " PUNCT fnp-5983 1 240 in in ADP fnp-5983 1 241 the the DET fnp-5983 1 242 latest late ADJ fnp-5983 1 243 world world NOUN fnp-5983 1 244 health health NOUN fnp-5983 1 245 organization organization NOUN fnp-5983 1 246 ( ( PUNCT fnp-5983 1 247 who who PRON fnp-5983 1 248 ) ) PUNCT fnp-5983 1 249 classification classification NOUN fnp-5983 1 250 of of ADP fnp-5983 1 251 tumors tumor NOUN fnp-5983 1 252 of of ADP fnp-5983 1 253 the the DET fnp-5983 1 254 central central ADJ fnp-5983 1 255 nervous nervous ADJ fnp-5983 1 256 system system NOUN fnp-5983 1 257 ( ( PUNCT fnp-5983 1 258 2021 2021 NUM fnp-5983 1 259 ) ) PUNCT fnp-5983 2 1 [ [ X fnp-5983 2 2 1 1 NUM fnp-5983 2 3 ] ] PUNCT fnp-5983 2 4 , , PUNCT fnp-5983 2 5 after after ADP fnp-5983 2 6 the the DET fnp-5983 2 7 discovery discovery NOUN fnp-5983 2 8 of of ADP fnp-5983 2 9 mn1 mn1 PROPN fnp-5983 2 10 fusions fusion NOUN fnp-5983 2 11 ( ( PUNCT fnp-5983 2 12 with with ADP fnp-5983 2 13 bend2 bend2 NOUN fnp-5983 2 14 as as ADP fnp-5983 2 15 the the DET fnp-5983 2 16 main main ADJ fnp-5983 2 17 partner partner NOUN fnp-5983 2 18 gene gene NOUN fnp-5983 2 19 ) ) PUNCT fnp-5983 3 1 [ [ X fnp-5983 3 2 2 2 NUM fnp-5983 3 3 ] ] PUNCT fnp-5983 3 4 . . PUNCT fnp-5983 4 1 the the DET fnp-5983 4 2 presence presence NOUN fnp-5983 4 3 of of ADP fnp-5983 4 4 this this DET fnp-5983 4 5 alteration alteration NOUN fnp-5983 4 6 constitutes constitute VERB fnp-5983 4 7 an an DET fnp-5983 4 8 essential essential ADJ fnp-5983 4 9 diagnostic diagnostic ADJ fnp-5983 4 10 criterion criterion NOUN fnp-5983 4 11 for for ADP fnp-5983 4 12 this this DET fnp-5983 4 13 tumor tumor NOUN fnp-5983 4 14 type type NOUN fnp-5983 4 15 , , PUNCT fnp-5983 4 16 and and CCONJ fnp-5983 4 17 for for ADP fnp-5983 4 18 unresolved unresolved ADJ fnp-5983 4 19 lesions lesion NOUN fnp-5983 4 20 , , PUNCT fnp-5983 4 21 a a DET fnp-5983 4 22 dna dna NOUN fnp-5983 4 23 - - PUNCT fnp-5983 4 24 methylation methylation NOUN fnp-5983 4 25 profile profile NOUN fnp-5983 4 26 is be AUX fnp-5983 4 27 necessary necessary ADJ fnp-5983 4 28 to to PART fnp-5983 4 29 confirm confirm VERB fnp-5983 4 30 this this DET fnp-5983 4 31 diagnosis diagnosis NOUN fnp-5983 4 32 . . PUNCT fnp-5983 5 1 the the DET fnp-5983 5 2 recent recent ADJ fnp-5983 5 3 literature literature NOUN fnp-5983 5 4 has have AUX fnp-5983 5 5 concluded conclude VERB fnp-5983 5 6 that that SCONJ fnp-5983 5 7 bend2 bend2 NOUN fnp-5983 5 8 fusions fusion NOUN fnp-5983 5 9 ( ( PUNCT fnp-5983 5 10 without without ADP fnp-5983 5 11 the the DET fnp-5983 5 12 mn1 mn1 PROPN fnp-5983 5 13 gene gene NOUN fnp-5983 5 14 ) ) PUNCT fnp-5983 5 15 may may AUX fnp-5983 5 16 occur occur VERB fnp-5983 5 17 in in ADP fnp-5983 5 18 this this DET fnp-5983 5 19 tumor tumor NOUN fnp-5983 5 20 type type NOUN fnp-5983 5 21 . . PUNCT fnp-5983 6 1 herein herein NOUN fnp-5983 6 2 , , PUNCT fnp-5983 6 3 we we PRON fnp-5983 6 4 report report VERB fnp-5983 6 5 one one NUM fnp-5983 6 6 case case NOUN fnp-5983 6 7 of of ADP fnp-5983 6 8 astroblastoma astroblastoma NOUN fnp-5983 6 9 with with ADP fnp-5983 6 10 a a DET fnp-5983 6 11 novel novel ADJ fnp-5983 6 12 fus::bend2 fus::bend2 ADJ fnp-5983 6 13 fusion fusion NOUN fnp-5983 6 14 . . PUNCT fnp-5983 7 1 we we PRON fnp-5983 7 2 compare compare VERB fnp-5983 7 3 its its PRON fnp-5983 7 4 clinical clinical ADJ fnp-5983 7 5 , , PUNCT fnp-5983 7 6 histopathological histopathological ADJ fnp-5983 7 7 , , PUNCT fnp-5983 7 8 immunophenotypic immunophenotypic ADJ fnp-5983 7 9 , , PUNCT fnp-5983 7 10 genetic genetic ADJ fnp-5983 7 11 , , PUNCT fnp-5983 7 12 and and CCONJ fnp-5983 7 13 epigenetic epigenetic ADJ fnp-5983 7 14 features feature NOUN fnp-5983 7 15 with with ADP fnp-5983 7 16 those those PRON fnp-5983 7 17 previously previously ADV fnp-5983 7 18 described describe VERB fnp-5983 7 19 in in ADP fnp-5983 7 20 astroblastomas astroblastoma NOUN fnp-5983 7 21 , , PUNCT fnp-5983 7 22 mn1 mn1 X fnp-5983 7 23 and/or and/or CCONJ fnp-5983 7 24 bend2 bend2 VERB fnp-5983 7 25 fusion fusion NOUN fnp-5983 7 26 - - PUNCT fnp-5983 7 27 positive positive ADJ fnp-5983 7 28 . . PUNCT fnp-5983 8 1 figure figure NOUN fnp-5983 8 2 1 1 NUM fnp-5983 8 3 : : PUNCT fnp-5983 8 4 radiological radiological ADJ fnp-5983 8 5 and and CCONJ fnp-5983 8 6 histopathological histopathological ADJ fnp-5983 8 7 features feature NOUN fnp-5983 8 8 of of ADP fnp-5983 8 9 the the DET fnp-5983 8 10 tumor tumor NOUN fnp-5983 8 11 ( ( PUNCT fnp-5983 8 12 a a DET fnp-5983 8 13 – – PUNCT fnp-5983 8 14 b b NOUN fnp-5983 8 15 ) ) PUNCT fnp-5983 8 16 axial axial ADJ fnp-5983 8 17 unenhanced unenhance VERB fnp-5983 8 18 computerized computerized ADJ fnp-5983 8 19 tomodensitometry tomodensitometry NOUN fnp-5983 8 20 images image NOUN fnp-5983 8 21 of of ADP fnp-5983 8 22 the the DET fnp-5983 8 23 patient patient NOUN fnp-5983 8 24 , , PUNCT fnp-5983 8 25 showing show VERB fnp-5983 8 26 a a DET fnp-5983 8 27 hyperdense hyperdense NOUN fnp-5983 8 28 and and CCONJ fnp-5983 8 29 calcified calcify VERB fnp-5983 8 30 mass mass NOUN fnp-5983 8 31 extending extend VERB fnp-5983 8 32 from from ADP fnp-5983 8 33 the the DET fnp-5983 8 34 third third NOUN fnp-5983 8 35 to to ADP fnp-5983 8 36 the the DET fnp-5983 8 37 fourth fourth ADJ fnp-5983 8 38 ventricle ventricle NOUN fnp-5983 8 39 with with ADP fnp-5983 8 40 hydrocephalus hydrocephalus ADJ fnp-5983 8 41 and and CCONJ fnp-5983 8 42 intraventricular intraventricular ADJ fnp-5983 8 43 hemorrhage hemorrhage NOUN fnp-5983 8 44 . . PUNCT fnp-5983 9 1 ( ( PUNCT fnp-5983 9 2 c c X fnp-5983 9 3 ) ) PUNCT fnp-5983 9 4 an an DET fnp-5983 9 5 ependymoma ependymoma NOUN fnp-5983 9 6 - - PUNCT fnp-5983 9 7 like like ADJ fnp-5983 9 8 tumor tumor NOUN fnp-5983 9 9 with with ADP fnp-5983 9 10 astroblastic astroblastic ADJ fnp-5983 9 11 pseudorosettes pseudorosette NOUN fnp-5983 9 12 ( ( PUNCT fnp-5983 9 13 hps hps NOUN fnp-5983 9 14 , , PUNCT fnp-5983 9 15 magnification magnification NOUN fnp-5983 9 16 x100 x100 PROPN fnp-5983 9 17 and and CCONJ fnp-5983 9 18 x400 x400 PROPN fnp-5983 9 19 for for ADP fnp-5983 9 20 insert insert NOUN fnp-5983 9 21 ) ) PUNCT fnp-5983 9 22 . . PUNCT fnp-5983 10 1 ( ( PUNCT fnp-5983 10 2 d d X fnp-5983 10 3 ) ) PUNCT fnp-5983 10 4 expression expression NOUN fnp-5983 10 5 of of ADP fnp-5983 10 6 gfap gfap NOUN fnp-5983 10 7 by by ADP fnp-5983 10 8 tumor tumor NOUN fnp-5983 10 9 cells cell NOUN fnp-5983 10 10 ( ( PUNCT fnp-5983 10 11 magnification magnification NOUN fnp-5983 10 12 x400 x400 PROPN fnp-5983 10 13 ) ) PUNCT fnp-5983 10 14 . . PUNCT fnp-5983 11 1 ( ( PUNCT fnp-5983 11 2 e e X fnp-5983 11 3 ) ) PUNCT fnp-5983 11 4 ema ema NOUN fnp-5983 11 5 immunoexpression immunoexpression NOUN fnp-5983 11 6 by by ADP fnp-5983 11 7 tumor tumor NOUN fnp-5983 11 8 cells cell NOUN fnp-5983 11 9 ( ( PUNCT fnp-5983 11 10 magnification magnification NOUN fnp-5983 11 11 x400 x400 PROPN fnp-5983 11 12 ) ) PUNCT fnp-5983 11 13 . . PUNCT fnp-5983 12 1 scale scale NOUN fnp-5983 12 2 bars bar NOUN fnp-5983 12 3 represent represent VERB fnp-5983 12 4 60 60 NUM fnp-5983 12 5     SPACE fnp-5983 12 6 μm μm NOUN fnp-5983 12 7 for for ADP fnp-5983 12 8 figures figure NOUN fnp-5983 12 9 c c X fnp-5983 12 10 – – PUNCT fnp-5983 12 11 e. e. PROPN fnp-5983 12 12 hps hps NOUN fnp-5983 12 13 : : PUNCT fnp-5983 12 14 hematoxylin hematoxylin PROPN fnp-5983 12 15 phloxin phloxin PROPN fnp-5983 12 16 saffron saffron NOUN fnp-5983 12 17 . . PUNCT fnp-5983 13 1 case case NOUN fnp-5983 13 2 presentation presentation NOUN fnp-5983 13 3 in in ADP fnp-5983 13 4 2007 2007 NUM fnp-5983 13 5 , , PUNCT fnp-5983 13 6 a a DET fnp-5983 13 7 4 4 NUM fnp-5983 13 8 - - PUNCT fnp-5983 13 9 year year NOUN fnp-5983 13 10 - - PUNCT fnp-5983 13 11 old old ADJ fnp-5983 13 12 girl girl NOUN fnp-5983 13 13 presented present VERB fnp-5983 13 14 with with ADP fnp-5983 13 15 a a DET fnp-5983 13 16 hyperdense hyperdense NOUN fnp-5983 13 17 and and CCONJ fnp-5983 13 18 calcified calcify VERB fnp-5983 13 19 mass mass NOUN fnp-5983 13 20 extending extend VERB fnp-5983 13 21 from from ADP fnp-5983 13 22 the the DET fnp-5983 13 23 third third NOUN fnp-5983 13 24 to to ADP fnp-5983 13 25 the the DET fnp-5983 13 26 fourth fourth ADJ fnp-5983 13 27 ventricle ventricle NOUN fnp-5983 13 28 with with ADP fnp-5983 13 29 hydrocephalus hydrocephalus ADJ fnp-5983 13 30 and and CCONJ fnp-5983 13 31 intraventricular intraventricular ADJ fnp-5983 13 32 hemorrhage hemorrhage NOUN fnp-5983 13 33 ( ( PUNCT fnp-5983 13 34 figure figure NOUN fnp-5983 13 35     SPACE fnp-5983 13 36 1 1 NUM fnp-5983 13 37 a a DET fnp-5983 13 38 – – PUNCT fnp-5983 13 39 b b NOUN fnp-5983 13 40 ) ) PUNCT fnp-5983 13 41 . . PUNCT fnp-5983 14 1 the the DET fnp-5983 14 2 tumor tumor NOUN fnp-5983 14 3 was be AUX fnp-5983 14 4 partially partially ADV fnp-5983 14 5 resected resect VERB fnp-5983 14 6 , , PUNCT fnp-5983 14 7 and and CCONJ fnp-5983 14 8 a a DET fnp-5983 14 9 diagnosis diagnosis NOUN fnp-5983 14 10 of of ADP fnp-5983 14 11 ependymoma ependymoma NOUN fnp-5983 14 12 was be AUX fnp-5983 14 13 made make VERB fnp-5983 14 14 according accord VERB fnp-5983 14 15 to to ADP fnp-5983 14 16 the the DET fnp-5983 14 17 2007 2007 NUM fnp-5983 14 18 who who PRON fnp-5983 14 19 classification classification VERB fnp-5983 14 20 . . PUNCT fnp-5983 15 1 the the DET fnp-5983 15 2 tumor tumor NOUN fnp-5983 15 3 recurred recur VERB fnp-5983 15 4 14 14 NUM fnp-5983 15 5 months month NOUN fnp-5983 15 6 later later ADV fnp-5983 15 7 , , PUNCT fnp-5983 15 8 and and CCONJ fnp-5983 15 9 the the DET fnp-5983 15 10 patient patient NOUN fnp-5983 15 11 died die VERB fnp-5983 15 12 69 69 NUM fnp-5983 15 13 months month NOUN fnp-5983 15 14 after after ADP fnp-5983 15 15 the the DET fnp-5983 15 16 initial initial ADJ fnp-5983 15 17 diagnosis diagnosis NOUN fnp-5983 15 18 . . PUNCT fnp-5983 16 1 in in ADP fnp-5983 16 2 2024 2024 NUM fnp-5983 16 3 , , PUNCT fnp-5983 16 4 a a DET fnp-5983 16 5 review review NOUN fnp-5983 16 6 of of ADP fnp-5983 16 7 the the DET fnp-5983 16 8 diagnosis diagnosis NOUN fnp-5983 16 9 was be AUX fnp-5983 16 10 performed perform VERB fnp-5983 16 11 . . PUNCT fnp-5983 17 1 microscopically microscopically ADV fnp-5983 17 2 , , PUNCT fnp-5983 17 3 the the DET fnp-5983 17 4 re re NOUN fnp-5983 17 5 - - NOUN fnp-5983 17 6 examination examination NOUN fnp-5983 17 7 showed show VERB fnp-5983 17 8 a a DET fnp-5983 17 9 tumor tumor NOUN fnp-5983 17 10 having have VERB fnp-5983 17 11 an an DET fnp-5983 17 12 ependymoma ependymoma NOUN fnp-5983 17 13 - - PUNCT fnp-5983 17 14 like like ADJ fnp-5983 17 15 pattern pattern NOUN fnp-5983 17 16 with with ADP fnp-5983 17 17 astroblastic astroblastic ADJ fnp-5983 17 18 pseudorosettes pseudorosette NOUN fnp-5983 17 19 ( ( PUNCT fnp-5983 17 20 figure figure NOUN fnp-5983 17 21     SPACE fnp-5983 17 22 1c 1c NOUN fnp-5983 17 23 ) ) PUNCT fnp-5983 17 24 . . PUNCT fnp-5983 18 1 there there PRON fnp-5983 18 2 was be VERB fnp-5983 18 3 no no DET fnp-5983 18 4 clear clear ADJ fnp-5983 18 5 cell cell NOUN fnp-5983 18 6 component component NOUN fnp-5983 18 7 , , PUNCT fnp-5983 18 8 no no DET fnp-5983 18 9 hyalinized hyalinize VERB fnp-5983 18 10 fibrous fibrous ADJ fnp-5983 18 11 stroma stroma NOUN fnp-5983 18 12 nor nor CCONJ fnp-5983 18 13 pas pas NOUN fnp-5983 18 14 - - PUNCT fnp-5983 18 15 positive positive ADJ fnp-5983 18 16 eosinophilic eosinophilic ADJ fnp-5983 18 17 granular granular ADJ fnp-5983 18 18 bodies body NOUN fnp-5983 18 19 . . PUNCT fnp-5983 19 1 there there PRON fnp-5983 19 2 was be VERB fnp-5983 19 3 no no DET fnp-5983 19 4 microvascular microvascular ADJ fnp-5983 19 5 proliferation proliferation NOUN fnp-5983 19 6 or or CCONJ fnp-5983 19 7 necrosis necrosis NOUN fnp-5983 19 8 . . PUNCT fnp-5983 20 1 mitotic mitotic ADJ fnp-5983 20 2 figures figure NOUN fnp-5983 20 3 were be AUX fnp-5983 20 4 scarce scarce ADJ fnp-5983 20 5 , , PUNCT fnp-5983 20 6 and and CCONJ fnp-5983 20 7 the the DET fnp-5983 20 8 mib1 mib1 NOUN fnp-5983 20 9 - - PUNCT fnp-5983 20 10 labeling labeling NOUN fnp-5983 20 11 index index NOUN fnp-5983 20 12 was be AUX fnp-5983 20 13 low low ADJ fnp-5983 20 14 ( ( PUNCT fnp-5983 20 15 5 5 NUM fnp-5983 20 16     SPACE fnp-5983 20 17 % % NOUN fnp-5983 20 18 ) ) PUNCT fnp-5983 20 19 . . PUNCT fnp-5983 21 1 the the DET fnp-5983 21 2 expression expression NOUN fnp-5983 21 3 of of ADP fnp-5983 21 4 brg1 brg1 PROPN fnp-5983 21 5 , , PUNCT fnp-5983 21 6 ini1 ini1 PROPN fnp-5983 21 7 and and CCONJ fnp-5983 21 8 h3k27me3 h3k27me3 PROPN fnp-5983 21 9 was be AUX fnp-5983 21 10 retained retain VERB fnp-5983 21 11 . . PUNCT fnp-5983 22 1 the the DET fnp-5983 22 2 tumor tumor NOUN fnp-5983 22 3 cells cell NOUN fnp-5983 22 4 expressed express VERB fnp-5983 22 5 gfap gfap ADJ fnp-5983 22 6 and and CCONJ fnp-5983 22 7 ema ema PROPN fnp-5983 22 8 with with ADP fnp-5983 22 9 a a DET fnp-5983 22 10 dot dot NOUN fnp-5983 22 11 - - PUNCT fnp-5983 22 12 like like NOUN fnp-5983 22 13 and and CCONJ fnp-5983 22 14 a a DET fnp-5983 22 15 microlumen microlumen NOUN fnp-5983 22 16 pattern pattern NOUN fnp-5983 22 17 ( ( PUNCT fnp-5983 22 18 figure figure NOUN fnp-5983 22 19     SPACE fnp-5983 22 20 1 1 NUM fnp-5983 22 21 d d PROPN fnp-5983 22 22 – – PUNCT fnp-5983 22 23 e e NOUN fnp-5983 22 24 ) ) PUNCT fnp-5983 22 25 . . PUNCT fnp-5983 23 1 there there PRON fnp-5983 23 2 was be VERB fnp-5983 23 3 no no DET fnp-5983 23 4 immunoreactivity immunoreactivity NOUN fnp-5983 23 5 for for ADP fnp-5983 23 6 olig2 olig2 NOUN fnp-5983 23 7 , , PUNCT fnp-5983 23 8 ck18 ck18 PROPN fnp-5983 23 9 , , PUNCT fnp-5983 23 10 lin28a lin28a PROPN fnp-5983 23 11 , , PUNCT fnp-5983 23 12 nfκb nfκb NOUN fnp-5983 23 13 , , PUNCT fnp-5983 23 14 l1cam l1cam PRON fnp-5983 23 15 or or CCONJ fnp-5983 23 16 neurofilaments neurofilament NOUN fnp-5983 23 17 . . PUNCT fnp-5983 24 1 fish fish NOUN fnp-5983 24 2 analysis analysis NOUN fnp-5983 24 3 of of ADP fnp-5983 24 4 the the DET fnp-5983 24 5 mn1 mn1 PROPN fnp-5983 24 6 gene gene NOUN fnp-5983 24 7 failed fail VERB fnp-5983 24 8 to to PART fnp-5983 24 9 reveal reveal VERB fnp-5983 24 10 a a DET fnp-5983 24 11 rearrangement rearrangement NOUN fnp-5983 24 12 , , PUNCT fnp-5983 24 13 and and CCONJ fnp-5983 24 14 rna rna NOUN fnp-5983 24 15 sequencing sequencing NOUN fnp-5983 24 16 evidenced evidence VERB fnp-5983 24 17 a a DET fnp-5983 24 18 fus::bend2 fus::bend2 ADJ fnp-5983 24 19 gene gene NOUN fnp-5983 24 20 fusion fusion NOUN fnp-5983 24 21 ( ( PUNCT fnp-5983 24 22 figure figure NOUN fnp-5983 24 23     SPACE fnp-5983 24 24 2a 2a NUM fnp-5983 24 25 – – PUNCT fnp-5983 24 26 b b NOUN fnp-5983 24 27 ) ) PUNCT fnp-5983 24 28 . . PUNCT fnp-5983 25 1 additionally additionally ADV fnp-5983 25 2 , , PUNCT fnp-5983 25 3 dna dna NOUN fnp-5983 25 4 - - PUNCT fnp-5983 25 5 methylation methylation NOUN fnp-5983 25 6 analysis analysis NOUN fnp-5983 25 7 was be AUX fnp-5983 25 8 conducted conduct VERB fnp-5983 25 9 . . PUNCT fnp-5983 26 1 the the DET fnp-5983 26 2 tumor tumor NOUN fnp-5983 26 3 was be AUX fnp-5983 26 4 not not PART fnp-5983 26 5 classifiable classifiable ADJ fnp-5983 26 6 using use VERB fnp-5983 26 7 the the DET fnp-5983 26 8 heidelberg heidelberg NOUN fnp-5983 26 9 brain brain NOUN fnp-5983 26 10 tumor tumor NOUN fnp-5983 26 11 classifier classifier NOUN fnp-5983 26 12 ( ( PUNCT fnp-5983 26 13 v12.8 v12.8 NUM fnp-5983 26 14 ) ) PUNCT fnp-5983 26 15 and and CCONJ fnp-5983 26 16 the the DET fnp-5983 26 17 bethesda bethesda PROPN fnp-5983 26 18 brain brain PROPN fnp-5983 26 19 tumor tumor NOUN fnp-5983 26 20 classifier classifier NOUN fnp-5983 26 21 ( ( PUNCT fnp-5983 26 22 v2 v2 PROPN fnp-5983 26 23 ) ) PUNCT fnp-5983 26 24 , , PUNCT fnp-5983 26 25 but but CCONJ fnp-5983 26 26 clustered cluster VERB fnp-5983 26 27 within within ADP fnp-5983 26 28 astroblastoma astroblastoma NOUN fnp-5983 26 29 , , PUNCT fnp-5983 26 30 ewsr1::bend2 ewsr1::bend2 NOUN fnp-5983 26 31 methylation methylation NOUN fnp-5983 26 32 class class NOUN fnp-5983 26 33 using use VERB fnp-5983 26 34 the the DET fnp-5983 26 35 uniform uniform ADJ fnp-5983 26 36 manifold manifold ADJ fnp-5983 26 37 approximation approximation NOUN fnp-5983 26 38 and and CCONJ fnp-5983 26 39 projection projection NOUN fnp-5983 26 40 ( ( PUNCT fnp-5983 26 41 umap umap ADJ fnp-5983 26 42 ) ) PUNCT fnp-5983 26 43 method method NOUN fnp-5983 26 44 ( ( PUNCT fnp-5983 26 45 supplementary supplementary ADJ fnp-5983 26 46 figure figure NOUN fnp-5983 26 47     SPACE fnp-5983 26 48 1 1 NUM fnp-5983 26 49 ) ) PUNCT fnp-5983 26 50 . . PUNCT fnp-5983 27 1 because because SCONJ fnp-5983 27 2 of of ADP fnp-5983 27 3 the the DET fnp-5983 27 4 histopathological histopathological ADJ fnp-5983 27 5 features feature NOUN fnp-5983 27 6 and and CCONJ fnp-5983 27 7 the the DET fnp-5983 27 8 presence presence NOUN fnp-5983 27 9 of of ADP fnp-5983 27 10 a a DET fnp-5983 27 11 bend2 bend2 NOUN fnp-5983 27 12 fusion fusion NOUN fnp-5983 27 13 , , PUNCT fnp-5983 27 14 the the DET fnp-5983 27 15 integrated integrated ADJ fnp-5983 27 16 diagnosis diagnosis NOUN fnp-5983 27 17 was be AUX fnp-5983 27 18 an an DET fnp-5983 27 19 astroblastoma astroblastoma NOUN fnp-5983 27 20 , , PUNCT fnp-5983 27 21 bend2 bend2 NOUN fnp-5983 27 22 fusion fusion NOUN fnp-5983 27 23 - - PUNCT fnp-5983 27 24 positive positive ADJ fnp-5983 27 25 . . PUNCT fnp-5983 28 1 figure figure NOUN fnp-5983 28 2 2 2 NUM fnp-5983 28 3 : : PUNCT fnp-5983 28 4 genetic genetic ADJ fnp-5983 28 5 features feature NOUN fnp-5983 28 6 ( ( PUNCT fnp-5983 28 7 a a PRON fnp-5983 28 8 ) ) PUNCT fnp-5983 28 9 rnaseq rnaseq NOUN fnp-5983 28 10 analysis analysis NOUN fnp-5983 28 11 highlights highlight NOUN fnp-5983 28 12 a a DET fnp-5983 28 13 fusion fusion NOUN fnp-5983 28 14 between between ADP fnp-5983 28 15 fus fus PROPN fnp-5983 28 16 ( ( PUNCT fnp-5983 28 17 pink pink ADJ fnp-5983 28 18 ) ) PUNCT fnp-5983 28 19 and and CCONJ fnp-5983 28 20 bend2 bend2 NOUN fnp-5983 28 21 ( ( PUNCT fnp-5983 28 22 blue blue ADJ fnp-5983 28 23 ) ) PUNCT fnp-5983 28 24 genes gene NOUN fnp-5983 28 25 , , PUNCT fnp-5983 28 26 respectively respectively ADV fnp-5983 28 27 located locate VERB fnp-5983 28 28 on on ADP fnp-5983 28 29 chr16p11.2 chr16p11.2 ADJ fnp-5983 28 30 and and CCONJ fnp-5983 28 31 chrxp22.13 chrxp22.13 PROPN fnp-5983 28 32 . . PUNCT fnp-5983 29 1 ( ( PUNCT fnp-5983 29 2 b b X fnp-5983 29 3 ) ) PUNCT fnp-5983 29 4 chimeric chimeric ADJ fnp-5983 29 5 protein protein NOUN fnp-5983 29 6 between between ADP fnp-5983 29 7 fus fus PROPN fnp-5983 29 8 and and CCONJ fnp-5983 29 9 bend2 bend2 NOUN fnp-5983 29 10 with with ADP fnp-5983 29 11 two two NUM fnp-5983 29 12 retained retain VERB fnp-5983 29 13 ben ben PROPN fnp-5983 29 14 protein protein NOUN fnp-5983 29 15 domains domain NOUN fnp-5983 29 16 of of ADP fnp-5983 29 17 bend2 bend2 NOUN fnp-5983 29 18 . . PUNCT fnp-5983 30 1 discussion discussion NOUN fnp-5983 30 2 and and CCONJ fnp-5983 30 3 conclusions conclusion NOUN fnp-5983 30 4 the the DET fnp-5983 30 5 current current ADJ fnp-5983 30 6 literature literature NOUN fnp-5983 30 7 review review NOUN fnp-5983 30 8 includes include VERB fnp-5983 30 9 92 92 NUM fnp-5983 30 10 cases case NOUN fnp-5983 30 11 of of ADP fnp-5983 30 12 astroblastomas astroblastoma NOUN fnp-5983 30 13 that that SCONJ fnp-5983 30 14 either either CCONJ fnp-5983 30 15 carried carry VERB fnp-5983 30 16 a a DET fnp-5983 30 17 mn1 mn1 NOUN fnp-5983 30 18 fusion fusion NOUN fnp-5983 30 19 or or CCONJ fnp-5983 30 20 had have VERB fnp-5983 30 21 a a DET fnp-5983 30 22 methylation methylation NOUN fnp-5983 30 23 profile profile NOUN fnp-5983 30 24 compatible compatible ADJ fnp-5983 30 25 with with ADP fnp-5983 30 26 astroblastoma astroblastoma NOUN fnp-5983 30 27 , , PUNCT fnp-5983 30 28 mn1 mn1 PROPN fnp-5983 30 29 - - PUNCT fnp-5983 30 30 altered alter VERB fnp-5983 30 31 [ [ X fnp-5983 30 32 2–28 2–28 NUM fnp-5983 30 33 ] ] PUNCT fnp-5983 30 34 ( ( PUNCT fnp-5983 30 35 see see VERB fnp-5983 30 36 supplementary supplementary ADJ fnp-5983 30 37 table table NOUN fnp-5983 30 38     SPACE fnp-5983 30 39 1 1 NUM fnp-5983 30 40 for for ADP fnp-5983 30 41 literature literature NOUN fnp-5983 30 42 review review PROPN fnp-5983 30 43 ) ) PUNCT fnp-5983 30 44 . . PUNCT fnp-5983 31 1 the the DET fnp-5983 31 2 majority majority NOUN fnp-5983 31 3 of of ADP fnp-5983 31 4 cases case NOUN fnp-5983 31 5 are be AUX fnp-5983 31 6 supratentorial supratentorial ADJ fnp-5983 31 7 ( ( PUNCT fnp-5983 31 8 84 84 NUM fnp-5983 31 9     SPACE fnp-5983 31 10 % % NOUN fnp-5983 31 11 , , PUNCT fnp-5983 31 12 72/86 72/86 NUM fnp-5983 31 13 tumors tumor NOUN fnp-5983 31 14 with with ADP fnp-5983 31 15 available available ADJ fnp-5983 31 16 data datum NOUN fnp-5983 31 17 ) ) PUNCT fnp-5983 32 1 [ [ X fnp-5983 32 2 2–28 2–28 NUM fnp-5983 32 3 ] ] PUNCT fnp-5983 32 4 . . PUNCT fnp-5983 33 1 most most ADJ fnp-5983 33 2 patients patient NOUN fnp-5983 33 3 are be AUX fnp-5983 33 4 pediatric pediatric ADJ fnp-5983 33 5 ( ( PUNCT fnp-5983 33 6 78 78 NUM fnp-5983 33 7     SPACE fnp-5983 33 8 % % NOUN fnp-5983 33 9 , , PUNCT fnp-5983 33 10 67/86 67/86 NUM fnp-5983 33 11 cases case NOUN fnp-5983 33 12 with with ADP fnp-5983 33 13 available available ADJ fnp-5983 33 14 data datum NOUN fnp-5983 33 15 ) ) PUNCT fnp-5983 34 1 [ [ X fnp-5983 34 2 2–28 2–28 NUM fnp-5983 34 3 ] ] PUNCT fnp-5983 34 4 . . PUNCT fnp-5983 35 1 however however ADV fnp-5983 35 2 , , PUNCT fnp-5983 35 3 this this DET fnp-5983 35 4 tumor tumor NOUN fnp-5983 35 5 occurs occur VERB fnp-5983 35 6 in in ADP fnp-5983 35 7 a a DET fnp-5983 35 8 wide wide ADJ fnp-5983 35 9 age age NOUN fnp-5983 35 10 range range NOUN fnp-5983 35 11 ( ( PUNCT fnp-5983 35 12 0–60 0–60 NOUN fnp-5983 35 13 years year NOUN fnp-5983 35 14 ) ) PUNCT fnp-5983 36 1 [ [ X fnp-5983 36 2 11,23 11,23 NOUN fnp-5983 36 3 ] ] PUNCT fnp-5983 36 4 . . PUNCT fnp-5983 37 1 typical typical ADJ fnp-5983 37 2 histopathological histopathological ADJ fnp-5983 37 3 features feature NOUN fnp-5983 37 4 include include VERB fnp-5983 37 5 an an DET fnp-5983 37 6 ependymoma ependymoma NOUN fnp-5983 37 7 - - PUNCT fnp-5983 37 8 like like ADJ fnp-5983 37 9 pattern pattern NOUN fnp-5983 37 10 , , PUNCT fnp-5983 37 11 astroblastic astroblastic ADJ fnp-5983 37 12 pseudorosettes pseudorosette NOUN fnp-5983 37 13 and and CCONJ fnp-5983 37 14 stromal stromal ADJ fnp-5983 37 15 sclerosis sclerosis NOUN fnp-5983 37 16 . . PUNCT fnp-5983 38 1 as as ADP fnp-5983 38 2 ependymomas ependymoma NOUN fnp-5983 38 3 , , PUNCT fnp-5983 38 4 tumor tumor NOUN fnp-5983 38 5 cells cell NOUN fnp-5983 38 6 frequently frequently ADV fnp-5983 38 7 express express VERB fnp-5983 38 8 gfap gfap ADJ fnp-5983 38 9 [ [ X fnp-5983 38 10 3,4,6–11,14–19,22–25,27 3,4,6–11,14–19,22–25,27 NUM fnp-5983 38 11 ] ] PUNCT fnp-5983 38 12 and and CCONJ fnp-5983 38 13 ema ema X fnp-5983 39 1 [ [ X fnp-5983 39 2 3,4,6,8–11,14,16–19,21,22,25,28 3,4,6,8–11,14,16–19,21,22,25,28 X fnp-5983 39 3 ] ] X fnp-5983 39 4 with with ADP fnp-5983 39 5 a a DET fnp-5983 39 6 variable variable ADJ fnp-5983 39 7 olig2 olig2 NOUN fnp-5983 39 8 immunopositivity immunopositivity NOUN fnp-5983 39 9 [ [ X fnp-5983 39 10 3,4,7,9–11,11,13,15–17,19,21–25,28 3,4,7,9–11,11,13,15–17,19,21–25,28 NUM fnp-5983 39 11 ] ] X fnp-5983 39 12 . . PUNCT fnp-5983 40 1 a a DET fnp-5983 40 2 mn1 mn1 PROPN fnp-5983 40 3 gene gene NOUN fnp-5983 40 4 fusion fusion NOUN fnp-5983 40 5 is be AUX fnp-5983 40 6 found find VERB fnp-5983 40 7 in in ADP fnp-5983 40 8 84 84 NUM fnp-5983 40 9     SPACE fnp-5983 40 10 % % NOUN fnp-5983 40 11 of of ADP fnp-5983 40 12 astroblastomas astroblastoma NOUN fnp-5983 40 13 ( ( PUNCT fnp-5983 40 14 54/64 54/64 NUM fnp-5983 40 15 reported report VERB fnp-5983 40 16 cases case NOUN fnp-5983 40 17 with with ADP fnp-5983 40 18 genetic genetic ADJ fnp-5983 40 19 analyses analysis NOUN fnp-5983 40 20 , , PUNCT fnp-5983 40 21 the the DET fnp-5983 40 22 28 28 NUM fnp-5983 40 23 remaining remain VERB fnp-5983 40 24 cases case NOUN fnp-5983 40 25 being be AUX fnp-5983 40 26 only only ADV fnp-5983 40 27 diagnosed diagnose VERB fnp-5983 40 28 using use VERB fnp-5983 40 29 dna dna PROPN fnp-5983 40 30 - - PUNCT fnp-5983 40 31 methylation methylation NOUN fnp-5983 40 32 profiling profiling NOUN fnp-5983 40 33 analysis analysis NOUN fnp-5983 40 34 ) ) PUNCT fnp-5983 40 35 , , PUNCT fnp-5983 40 36 mainly mainly ADV fnp-5983 40 37 in in ADP fnp-5983 40 38 association association NOUN fnp-5983 40 39 with with ADP fnp-5983 40 40 the the DET fnp-5983 40 41 bend2 bend2 NOUN fnp-5983 40 42 gene gene NOUN fnp-5983 40 43 ( ( PUNCT fnp-5983 40 44 94 94 NUM fnp-5983 40 45     SPACE fnp-5983 40 46 % % NOUN fnp-5983 40 47 , , PUNCT fnp-5983 40 48 17/18 17/18 NUM fnp-5983 40 49 cases case NOUN fnp-5983 40 50 with with ADP fnp-5983 40 51 rna rna NOUN fnp-5983 40 52 - - PUNCT fnp-5983 40 53 sequencing sequence VERB fnp-5983 40 54 data datum NOUN fnp-5983 40 55 , , PUNCT fnp-5983 40 56 the the DET fnp-5983 40 57 36 36 NUM fnp-5983 40 58 remaining remain VERB fnp-5983 40 59 cases case NOUN fnp-5983 40 60 being be AUX fnp-5983 40 61 only only ADV fnp-5983 40 62 diagnosed diagnose VERB fnp-5983 40 63 using use VERB fnp-5983 40 64 fish fish NOUN fnp-5983 40 65 mn1 mn1 PROPN fnp-5983 40 66 ) ) PUNCT fnp-5983 41 1 [ [ X fnp-5983 41 2 2–4,6–16,18–28 2–4,6–16,18–28 X fnp-5983 41 3 ] ] PUNCT fnp-5983 41 4 . . PUNCT fnp-5983 42 1 one one NUM fnp-5983 42 2 tumor tumor NOUN fnp-5983 42 3 harbored harbor VERB fnp-5983 42 4 a a DET fnp-5983 42 5 mn1::cxxc5 mn1::cxxc5 NOUN fnp-5983 42 6 fusion fusion NOUN fnp-5983 42 7 [ [ X fnp-5983 42 8 2 2 NUM fnp-5983 42 9 ] ] PUNCT fnp-5983 42 10 . . PUNCT fnp-5983 43 1 alternative alternative ADJ fnp-5983 43 2 fusions fusion NOUN fnp-5983 43 3 including include VERB fnp-5983 43 4 the the DET fnp-5983 43 5 bend2 bend2 NOUN fnp-5983 43 6 gene gene NOUN fnp-5983 43 7 without without ADP fnp-5983 43 8 mn1 mn1 PROPN fnp-5983 43 9 have have AUX fnp-5983 43 10 been be AUX fnp-5983 43 11 reported report VERB fnp-5983 43 12 in in ADP fnp-5983 43 13 ten ten NUM fnp-5983 43 14 tumors tumor NOUN fnp-5983 43 15 ( ( PUNCT fnp-5983 43 16 7 7 NUM fnp-5983 43 17 with with ADP fnp-5983 43 18 ewsr1 ewsr1 PROPN fnp-5983 43 19 , , PUNCT fnp-5983 43 20 2 2 NUM fnp-5983 43 21 with with ADP fnp-5983 43 22 mamld1 mamld1 ADJ fnp-5983 43 23 , , PUNCT fnp-5983 43 24 and and CCONJ fnp-5983 43 25 one one NUM fnp-5983 43 26 with with ADP fnp-5983 43 27 yap1 yap1 PROPN fnp-5983 43 28 ) ) PUNCT fnp-5983 44 1 [ [ X fnp-5983 44 2 3,4,8,19,22,23,27 3,4,8,19,22,23,27 NUM fnp-5983 44 3 ] ] PUNCT fnp-5983 44 4 . . PUNCT fnp-5983 45 1 moreover moreover ADV fnp-5983 45 2 , , PUNCT fnp-5983 45 3 an an DET fnp-5983 45 4 ewsr1::ezhip ewsr1::ezhip NOUN fnp-5983 45 5 fusion fusion NOUN fnp-5983 45 6 was be AUX fnp-5983 45 7 identified identify VERB fnp-5983 45 8 in in ADP fnp-5983 45 9 an an DET fnp-5983 45 10 astroblastoma astroblastoma NOUN fnp-5983 45 11 ; ; PUNCT fnp-5983 45 12 however however ADV fnp-5983 45 13 , , PUNCT fnp-5983 45 14 no no DET fnp-5983 45 15 methylation methylation NOUN fnp-5983 45 16 - - PUNCT fnp-5983 45 17 based base VERB fnp-5983 45 18 classification classification NOUN fnp-5983 45 19 was be AUX fnp-5983 45 20 available available ADJ fnp-5983 45 21 for for ADP fnp-5983 45 22 this this DET fnp-5983 45 23 tumor tumor NOUN fnp-5983 46 1 [ [ X fnp-5983 46 2 29 29 NUM fnp-5983 46 3 ] ] PUNCT fnp-5983 46 4 . . PUNCT fnp-5983 47 1 in in ADP fnp-5983 47 2 this this DET fnp-5983 47 3 study study NOUN fnp-5983 47 4 , , PUNCT fnp-5983 47 5 we we PRON fnp-5983 47 6 report report VERB fnp-5983 47 7 for for ADP fnp-5983 47 8 the the DET fnp-5983 47 9 first first ADJ fnp-5983 47 10 time time NOUN fnp-5983 47 11 a a DET fnp-5983 47 12 fus::bend2 fus::bend2 ADJ fnp-5983 47 13 fusion fusion NOUN fnp-5983 47 14 in in ADP fnp-5983 47 15 astroblastoma astroblastoma NOUN fnp-5983 47 16 . . PUNCT fnp-5983 48 1 this this DET fnp-5983 48 2 novel novel ADJ fnp-5983 48 3 gene gene NOUN fnp-5983 48 4 rearrangement rearrangement NOUN fnp-5983 48 5 results result NOUN fnp-5983 48 6 in in ADP fnp-5983 48 7 an an DET fnp-5983 48 8 in in ADP fnp-5983 48 9 - - PUNCT fnp-5983 48 10 frame frame NOUN fnp-5983 48 11 fusion fusion NOUN fnp-5983 48 12 of of ADP fnp-5983 48 13 exons exon NOUN fnp-5983 48 14 1 1 NUM fnp-5983 48 15 to to PART fnp-5983 48 16 5 5 NUM fnp-5983 48 17 of of ADP fnp-5983 48 18 the the DET fnp-5983 48 19 fus fus PROPN fnp-5983 48 20 gene gene NOUN fnp-5983 48 21 and and CCONJ fnp-5983 48 22 exons exon NOUN fnp-5983 48 23 2 2 NUM fnp-5983 48 24 to to ADP fnp-5983 48 25 14 14 NUM fnp-5983 48 26 of of ADP fnp-5983 48 27 the the DET fnp-5983 48 28 bend2 bend2 NOUN fnp-5983 48 29 gene gene NOUN fnp-5983 48 30 , , PUNCT fnp-5983 48 31 the the DET fnp-5983 48 32 same same ADJ fnp-5983 48 33 breakpoint breakpoint NOUN fnp-5983 48 34 as as SCONJ fnp-5983 48 35 previously previously ADV fnp-5983 48 36 reported report VERB fnp-5983 48 37 [ [ PUNCT fnp-5983 48 38 3,4 3,4 NUM fnp-5983 48 39 ] ] PUNCT fnp-5983 48 40 . . PUNCT fnp-5983 49 1 in in ADP fnp-5983 49 2 the the DET fnp-5983 49 3 literature literature NOUN fnp-5983 49 4 , , PUNCT fnp-5983 49 5 we we PRON fnp-5983 49 6 identified identify VERB fnp-5983 49 7 two two NUM fnp-5983 49 8 reports report NOUN fnp-5983 49 9 of of ADP fnp-5983 49 10 a a DET fnp-5983 49 11 nasopharyngeal nasopharyngeal ADJ fnp-5983 49 12 and and CCONJ fnp-5983 49 13 soft soft ADJ fnp-5983 49 14 tissue tissue NOUN fnp-5983 49 15 sarcoma sarcoma NOUN fnp-5983 49 16 harboring harbor VERB fnp-5983 49 17 a a DET fnp-5983 49 18 fus::bend8 fus::bend8 PROPN fnp-5983 49 19 ( ( PUNCT fnp-5983 49 20 another another DET fnp-5983 49 21 gene gene NOUN fnp-5983 49 22 encoding encode VERB fnp-5983 49 23 a a DET fnp-5983 49 24 ben ben PROPN fnp-5983 49 25 domain domain NOUN fnp-5983 49 26 containing contain VERB fnp-5983 49 27 protein protein NOUN fnp-5983 49 28 ) ) PUNCT fnp-5983 49 29 fusion fusion NOUN fnp-5983 50 1 [ [ X fnp-5983 50 2 30,31 30,31 NOUN fnp-5983 50 3 ] ] PUNCT fnp-5983 50 4 . . PUNCT fnp-5983 51 1 the the DET fnp-5983 51 2 fus fus PROPN fnp-5983 51 3 gene gene NOUN fnp-5983 51 4 belongs belong VERB fnp-5983 51 5 to to ADP fnp-5983 51 6 the the DET fnp-5983 51 7 fet fet PROPN fnp-5983 51 8 family family NOUN fnp-5983 51 9 of of ADP fnp-5983 51 10 genes gene NOUN fnp-5983 51 11 which which PRON fnp-5983 51 12 encode encode VERB fnp-5983 51 13 for for ADP fnp-5983 51 14 rna rna NOUN fnp-5983 51 15 - - PUNCT fnp-5983 51 16 binding bind VERB fnp-5983 51 17 proteins protein NOUN fnp-5983 51 18 , , PUNCT fnp-5983 51 19 like like ADP fnp-5983 51 20 ewsr1 ewsr1 NOUN fnp-5983 51 21 [ [ X fnp-5983 51 22 32 32 NUM fnp-5983 51 23 ] ] PUNCT fnp-5983 51 24 . . PUNCT fnp-5983 52 1 the the DET fnp-5983 52 2 predicted predict VERB fnp-5983 52 3 fus fus PROPN fnp-5983 52 4 - - PUNCT fnp-5983 52 5 bend2 bend2 NOUN fnp-5983 52 6 chimeric chimeric ADJ fnp-5983 52 7 protein protein NOUN fnp-5983 52 8 maintained maintain VERB fnp-5983 52 9 two two NUM fnp-5983 52 10 ben ben PROPN fnp-5983 52 11 domains domain NOUN fnp-5983 52 12 in in ADP fnp-5983 52 13 the the DET fnp-5983 52 14 c c NOUN fnp-5983 52 15 - - PUNCT fnp-5983 52 16 terminus terminus NOUN fnp-5983 52 17 encoded encode VERB fnp-5983 52 18 by by ADP fnp-5983 52 19 bend2 bend2 PROPN fnp-5983 52 20 , , PUNCT fnp-5983 52 21 which which PRON fnp-5983 52 22 are be AUX fnp-5983 52 23 involved involve VERB fnp-5983 52 24 in in ADP fnp-5983 52 25 transcription transcription NOUN fnp-5983 52 26 and and CCONJ fnp-5983 52 27 chromatin chromatin NOUN fnp-5983 52 28 regulation regulation NOUN fnp-5983 52 29 [ [ X fnp-5983 52 30 33 33 NUM fnp-5983 52 31 ] ] PUNCT fnp-5983 52 32 . . PUNCT fnp-5983 53 1 as as SCONJ fnp-5983 53 2 was be AUX fnp-5983 53 3 found find VERB fnp-5983 53 4 for for ADP fnp-5983 53 5 our our PRON fnp-5983 53 6 case case NOUN fnp-5983 53 7 , , PUNCT fnp-5983 53 8 clinical clinical ADJ fnp-5983 53 9 findings finding NOUN fnp-5983 53 10 seem seem VERB fnp-5983 53 11 to to PART fnp-5983 53 12 be be AUX fnp-5983 53 13 different different ADJ fnp-5983 53 14 for for ADP fnp-5983 53 15 patients patient NOUN fnp-5983 53 16 who who PRON fnp-5983 53 17 have have VERB fnp-5983 53 18 an an DET fnp-5983 53 19 astroblastoma astroblastoma NOUN fnp-5983 53 20 , , PUNCT fnp-5983 53 21 bend2 bend2 NOUN fnp-5983 53 22 fusion fusion NOUN fnp-5983 53 23 - - PUNCT fnp-5983 53 24 positive positive ADJ fnp-5983 53 25 . . PUNCT fnp-5983 54 1 they they PRON fnp-5983 54 2 tend tend VERB fnp-5983 54 3 to to PART fnp-5983 54 4 present present VERB fnp-5983 54 5 in in ADP fnp-5983 54 6 a a DET fnp-5983 54 7 younger young ADJ fnp-5983 54 8 population population NOUN fnp-5983 54 9 ( ( PUNCT fnp-5983 54 10 median median ADJ fnp-5983 54 11 age age NOUN fnp-5983 54 12 of of ADP fnp-5983 54 13 6 6 NUM fnp-5983 54 14 years year NOUN fnp-5983 54 15 - - PUNCT fnp-5983 54 16 old old ADJ fnp-5983 54 17 at at ADP fnp-5983 54 18 diagnosis diagnosis NOUN fnp-5983 54 19 ) ) PUNCT fnp-5983 54 20 , , PUNCT fnp-5983 54 21 affect affect VERB fnp-5983 54 22 females female NOUN fnp-5983 54 23 less less ADV fnp-5983 54 24 frequently frequently ADV fnp-5983 54 25 ( ( PUNCT fnp-5983 54 26 with with ADP fnp-5983 54 27 a a DET fnp-5983 54 28 female female NOUN fnp-5983 54 29 - - PUNCT fnp-5983 54 30 to to ADP fnp-5983 54 31 - - PUNCT fnp-5983 54 32 male male NOUN fnp-5983 54 33 ratio ratio NOUN fnp-5983 54 34 of of ADP fnp-5983 54 35 1.75 1.75 NUM fnp-5983 54 36 ) ) PUNCT fnp-5983 54 37 , , PUNCT fnp-5983 54 38 and and CCONJ fnp-5983 54 39 be be AUX fnp-5983 54 40 mainly mainly ADV fnp-5983 54 41 infratentorial infratentorial ADJ fnp-5983 54 42 ( ( PUNCT fnp-5983 54 43 73 73 NUM fnp-5983 54 44     SPACE fnp-5983 54 45 % % NOUN fnp-5983 54 46 of of ADP fnp-5983 54 47 cases case NOUN fnp-5983 54 48 ) ) PUNCT fnp-5983 54 49 compared compare VERB fnp-5983 54 50 to to ADP fnp-5983 54 51 the the DET fnp-5983 54 52 astroblastomas astroblastoma NOUN fnp-5983 54 53 , , PUNCT fnp-5983 54 54 mn1 mn1 PROPN fnp-5983 54 55 - - PUNCT fnp-5983 54 56 altered altered ADJ fnp-5983 54 57 ( ( PUNCT fnp-5983 54 58 presenting present VERB fnp-5983 54 59 at at ADP fnp-5983 54 60 a a DET fnp-5983 54 61 median median ADJ fnp-5983 54 62 age age NOUN fnp-5983 54 63 of of ADP fnp-5983 54 64 10 10 NUM fnp-5983 54 65 years year NOUN fnp-5983 54 66 , , PUNCT fnp-5983 54 67 a a DET fnp-5983 54 68 female female NOUN fnp-5983 54 69 - - PUNCT fnp-5983 54 70 to to ADP fnp-5983 54 71 - - PUNCT fnp-5983 54 72 male male NOUN fnp-5983 54 73 ratio ratio NOUN fnp-5983 54 74 of of ADP fnp-5983 54 75 7.5 7.5 NUM fnp-5983 54 76 and and CCONJ fnp-5983 54 77 only only ADV fnp-5983 54 78 making make VERB fnp-5983 54 79 up up ADP fnp-5983 54 80 8 8 NUM fnp-5983 54 81     SPACE fnp-5983 54 82 % % NOUN fnp-5983 54 83 of of ADP fnp-5983 54 84 infratentorial infratentorial ADJ fnp-5983 54 85 tumors tumor NOUN fnp-5983 54 86 ) ) PUNCT fnp-5983 55 1 [ [ X fnp-5983 55 2 2–4,6–16,18–28 2–4,6–16,18–28 X fnp-5983 55 3 ] ] PUNCT fnp-5983 55 4 . . PUNCT fnp-5983 56 1 most most ADV fnp-5983 56 2 likely likely ADJ fnp-5983 56 3 due due ADP fnp-5983 56 4 to to ADP fnp-5983 56 5 the the DET fnp-5983 56 6 tumor tumor NOUN fnp-5983 56 7 location location NOUN fnp-5983 56 8 , , PUNCT fnp-5983 56 9 the the DET fnp-5983 56 10 prognosis prognosis NOUN fnp-5983 56 11 of of ADP fnp-5983 56 12 patients patient NOUN fnp-5983 56 13 with with ADP fnp-5983 56 14 astroblastomas astroblastoma NOUN fnp-5983 56 15 , , PUNCT fnp-5983 56 16 bend2 bend2 NOUN fnp-5983 56 17 fusion fusion NOUN fnp-5983 56 18 - - PUNCT fnp-5983 56 19 positive positive ADJ fnp-5983 56 20 is be AUX fnp-5983 56 21 worse bad ADJ fnp-5983 56 22 ( ( PUNCT fnp-5983 56 23 33 33 NUM fnp-5983 56 24     SPACE fnp-5983 56 25 % % NOUN fnp-5983 56 26 , , PUNCT fnp-5983 56 27 3/9 3/9 NUM fnp-5983 56 28 , , PUNCT fnp-5983 56 29 patients patient NOUN fnp-5983 56 30 died die VERB fnp-5983 56 31 with with ADP fnp-5983 56 32 a a DET fnp-5983 56 33 median median ADJ fnp-5983 56 34 overall overall ADJ fnp-5983 56 35 survival survival NOUN fnp-5983 56 36 of of ADP fnp-5983 56 37 25 25 NUM fnp-5983 56 38 months month NOUN fnp-5983 56 39 [ [ X fnp-5983 56 40 1;276 1;276 NUM fnp-5983 56 41 ] ] X fnp-5983 56 42 ) ) PUNCT fnp-5983 56 43 than than ADP fnp-5983 56 44 those those PRON fnp-5983 56 45 with with ADP fnp-5983 56 46 astroblastomas astroblastoma NOUN fnp-5983 56 47 , , PUNCT fnp-5983 56 48 mn1 mn1 PROPN fnp-5983 56 49 - - PUNCT fnp-5983 56 50 altered altered ADJ fnp-5983 56 51 ( ( PUNCT fnp-5983 56 52 14 14 NUM fnp-5983 56 53     SPACE fnp-5983 56 54 % % NOUN fnp-5983 56 55 of of ADP fnp-5983 56 56 patients patient NOUN fnp-5983 56 57 , , PUNCT fnp-5983 56 58 9/62 9/62 NUM fnp-5983 56 59 , , PUNCT fnp-5983 56 60 died die VERB fnp-5983 56 61 with with ADP fnp-5983 56 62 a a DET fnp-5983 56 63 median median ADJ fnp-5983 56 64 overall overall ADJ fnp-5983 56 65 survival survival NOUN fnp-5983 56 66 of of ADP fnp-5983 56 67 70 70 NUM fnp-5983 56 68 months month NOUN fnp-5983 56 69 [ [ X fnp-5983 56 70 3;324 3;324 NUM fnp-5983 56 71 ] ] PUNCT fnp-5983 56 72 ) ) PUNCT fnp-5983 56 73 . . PUNCT fnp-5983 57 1 the the DET fnp-5983 57 2 analysis analysis NOUN fnp-5983 57 3 of of ADP fnp-5983 57 4 the the DET fnp-5983 57 5 recent recent ADJ fnp-5983 57 6 literature literature NOUN fnp-5983 57 7 seems seem VERB fnp-5983 57 8 to to PART fnp-5983 57 9 suggest suggest VERB fnp-5983 57 10 that that SCONJ fnp-5983 57 11 it it PRON fnp-5983 57 12 may may AUX fnp-5983 57 13 be be AUX fnp-5983 57 14 bend2 bend2 NOUN fnp-5983 57 15 , , PUNCT fnp-5983 57 16 rather rather ADV fnp-5983 57 17 than than ADP fnp-5983 57 18 mn1 mn1 PROPN fnp-5983 57 19 , , PUNCT fnp-5983 57 20 which which PRON fnp-5983 57 21 has have VERB fnp-5983 57 22 a a DET fnp-5983 57 23 more more ADV fnp-5983 57 24 critical critical ADJ fnp-5983 57 25 functional functional ADJ fnp-5983 57 26 role role NOUN fnp-5983 57 27 in in ADP fnp-5983 57 28 the the DET fnp-5983 57 29 oncogenesis oncogenesis NOUN fnp-5983 57 30 of of ADP fnp-5983 57 31 astroblastomas astroblastoma NOUN fnp-5983 58 1 [ [ X fnp-5983 58 2 34 34 NUM fnp-5983 58 3 ] ] PUNCT fnp-5983 58 4 . . PUNCT fnp-5983 59 1 in in ADP fnp-5983 59 2 conclusion conclusion NOUN fnp-5983 59 3 , , PUNCT fnp-5983 59 4 we we PRON fnp-5983 59 5 expanded expand VERB fnp-5983 59 6 the the DET fnp-5983 59 7 astroblastoma astroblastoma NOUN fnp-5983 59 8 genetic genetic ADJ fnp-5983 59 9 spectrum spectrum NOUN fnp-5983 59 10 with with ADP fnp-5983 59 11 one one NUM fnp-5983 59 12 novel novel ADJ fnp-5983 59 13 fusion fusion NOUN fnp-5983 59 14 fus::bend2 fus::bend2 PROPN fnp-5983 59 15 . . PUNCT fnp-5983 60 1 reminiscent reminiscent ADJ fnp-5983 60 2 of of ADP fnp-5983 60 3 the the DET fnp-5983 60 4 terminological terminological ADJ fnp-5983 60 5 history history NOUN fnp-5983 60 6 of of ADP fnp-5983 60 7 supratentorial supratentorial ADJ fnp-5983 60 8 ependymomas ependymoma NOUN fnp-5983 60 9 , , PUNCT fnp-5983 60 10 originally originally ADV fnp-5983 60 11 referred refer VERB fnp-5983 60 12 to to ADP fnp-5983 60 13 as as ADP fnp-5983 60 14 “ " PUNCT fnp-5983 60 15 rela rela ADJ fnp-5983 60 16 - - PUNCT fnp-5983 60 17 fusion fusion NOUN fnp-5983 60 18 positive positive NOUN fnp-5983 60 19 ” " PUNCT fnp-5983 60 20 and and CCONJ fnp-5983 60 21 afterward afterward ADV fnp-5983 60 22 “ " PUNCT fnp-5983 60 23 zfta zfta NOUN fnp-5983 60 24 - - PUNCT fnp-5983 60 25 fused fuse VERB fnp-5983 60 26 ” " PUNCT fnp-5983 60 27 , , PUNCT fnp-5983 60 28 our our PRON fnp-5983 60 29 case case NOUN fnp-5983 60 30 supports support VERB fnp-5983 60 31 the the DET fnp-5983 60 32 consideration consideration NOUN fnp-5983 60 33 of of ADP fnp-5983 60 34 a a DET fnp-5983 60 35 bend2 bend2 NOUN fnp-5983 60 36 fusion fusion NOUN fnp-5983 60 37 as as ADP fnp-5983 60 38 the the DET fnp-5983 60 39 defining define VERB fnp-5983 60 40 alteration alteration NOUN fnp-5983 60 41 for for ADP fnp-5983 60 42 astroblastoma astroblastoma NOUN fnp-5983 60 43 , , PUNCT fnp-5983 60 44 rather rather ADV fnp-5983 60 45 than than ADP fnp-5983 60 46 the the DET fnp-5983 60 47 mn1 mn1 PROPN fnp-5983 60 48 rearrangement rearrangement NOUN fnp-5983 60 49 . . PUNCT fnp-5983 61 1 ethics ethic NOUN fnp-5983 61 2 approval approval NOUN fnp-5983 61 3 this this DET fnp-5983 61 4 study study NOUN fnp-5983 61 5 was be AUX fnp-5983 61 6 approved approve VERB fnp-5983 61 7 by by ADP fnp-5983 61 8 the the DET fnp-5983 61 9 ghu ghu NOUN fnp-5983 61 10 paris paris PROPN fnp-5983 61 11 psychiatrie psychiatrie NOUN fnp-5983 61 12 neurosciences neuroscience NOUN fnp-5983 61 13 , , PUNCT fnp-5983 61 14 sainte sainte PROPN fnp-5983 61 15 - - PUNCT fnp-5983 61 16 anne anne PROPN fnp-5983 61 17 hospital hospital PROPN fnp-5983 61 18 ’s ’s PART fnp-5983 61 19 local local ADJ fnp-5983 61 20 ethic ethic ADJ fnp-5983 61 21 committee committee NOUN fnp-5983 61 22 . . PUNCT fnp-5983 62 1 consent consent NOUN fnp-5983 62 2 for for ADP fnp-5983 62 3 publication publication NOUN fnp-5983 62 4 the the DET fnp-5983 62 5 patient patient NOUN fnp-5983 62 6 signed sign VERB fnp-5983 62 7 informed informed ADJ fnp-5983 62 8 consent consent NOUN fnp-5983 62 9 forms form NOUN fnp-5983 62 10 before before SCONJ fnp-5983 62 11 treatment treatment NOUN fnp-5983 62 12 was be AUX fnp-5983 62 13 started start VERB fnp-5983 62 14 . . PUNCT fnp-5983 63 1 competing compete VERB fnp-5983 63 2 interests interest NOUN fnp-5983 63 3 the the DET fnp-5983 63 4 authors author NOUN fnp-5983 63 5 declare declare VERB fnp-5983 63 6 that that SCONJ fnp-5983 63 7 they they PRON fnp-5983 63 8 have have VERB fnp-5983 63 9 no no DET fnp-5983 63 10 conflicts conflict NOUN fnp-5983 63 11 of of ADP fnp-5983 63 12 interest interest NOUN fnp-5983 63 13 directly directly ADV fnp-5983 63 14 related relate VERB fnp-5983 63 15 to to ADP fnp-5983 63 16 the the DET fnp-5983 63 17 topic topic NOUN fnp-5983 63 18 of of ADP fnp-5983 63 19 this this DET fnp-5983 63 20 article article NOUN fnp-5983 63 21 . . PUNCT fnp-5983 64 1 funding funding NOUN fnp-5983 64 2 statement statement NOUN fnp-5983 64 3 the the DET fnp-5983 64 4 authors author NOUN fnp-5983 64 5 declare declare VERB fnp-5983 64 6 that that SCONJ fnp-5983 64 7 they they PRON fnp-5983 64 8 have have AUX fnp-5983 64 9 not not PART fnp-5983 64 10 received receive VERB fnp-5983 64 11 any any DET fnp-5983 64 12 funding funding NOUN fnp-5983 64 13 . . PUNCT fnp-5983 65 1 authors author NOUN fnp-5983 65 2 ’ ’ PART fnp-5983 65 3 contributions contribution NOUN fnp-5983 65 4 ate eat VERB fnp-5983 65 5 , , PUNCT fnp-5983 65 6 vdr vdr NOUN fnp-5983 65 7 , , PUNCT fnp-5983 65 8 kb kb PROPN fnp-5983 65 9 and and CCONJ fnp-5983 65 10 nb nb PROPN fnp-5983 65 11 compiled compile VERB fnp-5983 65 12 the the DET fnp-5983 65 13 mri mri NOUN fnp-5983 65 14 and and CCONJ fnp-5983 65 15 clinical clinical ADJ fnp-5983 65 16 records record NOUN fnp-5983 65 17 ; ; PUNCT fnp-5983 65 18 ate eat VERB fnp-5983 65 19 , , PUNCT fnp-5983 65 20 am be AUX fnp-5983 65 21 and and CCONJ fnp-5983 65 22 pv pv PROPN fnp-5983 65 23 conducted conduct VERB fnp-5983 65 24 the the DET fnp-5983 65 25 neuropathological neuropathological ADJ fnp-5983 65 26 examinations examination NOUN fnp-5983 65 27 ; ; PUNCT fnp-5983 65 28 bb bb PRON fnp-5983 65 29 conducted conduct VERB fnp-5983 65 30 the the DET fnp-5983 65 31 molecular molecular ADJ fnp-5983 65 32 studies study NOUN fnp-5983 65 33 ; ; PUNCT fnp-5983 65 34 ate eat VERB fnp-5983 65 35 , , PUNCT fnp-5983 65 36 lh lh PROPN fnp-5983 65 37 , , PUNCT fnp-5983 65 38 and and CCONJ fnp-5983 65 39 pv pv INTJ fnp-5983 65 40 drafted draft VERB fnp-5983 65 41 the the DET fnp-5983 65 42 manuscript manuscript NOUN fnp-5983 65 43 . . PUNCT fnp-5983 66 1 all all DET fnp-5983 66 2 authors author NOUN fnp-5983 66 3 reviewed review VERB fnp-5983 66 4 the the DET fnp-5983 66 5 manuscript manuscript NOUN fnp-5983 66 6 . . PUNCT fnp-5983 67 1 acknowledgements acknowledgement NOUN fnp-5983 67 2 we we PRON fnp-5983 67 3 would would AUX fnp-5983 67 4 like like VERB fnp-5983 67 5 to to PART fnp-5983 67 6 thank thank VERB fnp-5983 67 7 the the DET fnp-5983 67 8 laboratory laboratory NOUN fnp-5983 67 9 technicians technician NOUN fnp-5983 67 10 at at ADP fnp-5983 67 11 the the DET fnp-5983 67 12 ghu ghu NOUN fnp-5983 67 13 paris paris PROPN fnp-5983 67 14 neuro neuro PROPN fnp-5983 67 15 sainte sainte PROPN fnp-5983 67 16 - - PUNCT fnp-5983 67 17 anne anne PROPN fnp-5983 67 18 for for ADP fnp-5983 67 19 their their PRON fnp-5983 67 20 assistance assistance NOUN fnp-5983 67 21 . . PUNCT fnp-5983 67 22     SPACE fnp-5983 68 1 supplementary supplementary ADJ fnp-5983 68 2 material material NOUN fnp-5983 68 3 supplementary supplementary ADJ fnp-5983 68 4 table table NOUN fnp-5983 68 5 01 01 NUM fnp-5983 68 6 ( ( PUNCT fnp-5983 68 7 download download NOUN fnp-5983 68 8 ) ) PUNCT fnp-5983 68 9 literature literature PROPN fnp-5983 68 10 review review PROPN fnp-5983 68 11 ( ( PUNCT fnp-5983 68 12 pdf pdf NOUN fnp-5983 68 13 ) ) PUNCT fnp-5983 68 14 supplementary supplementary ADJ fnp-5983 68 15 figure figure NOUN fnp-5983 68 16 01 01 NUM fnp-5983 68 17 ( ( PUNCT fnp-5983 68 18 download download NOUN fnp-5983 68 19 ) ) PUNCT fnp-5983 68 20 uniform uniform NOUN fnp-5983 68 21 manifold manifold ADJ fnp-5983 68 22 approximation approximation NOUN fnp-5983 68 23 and and CCONJ fnp-5983 68 24 projection projection NOUN fnp-5983 68 25 ( ( PUNCT fnp-5983 68 26 umap umap ADJ fnp-5983 68 27 ) ) PUNCT fnp-5983 68 28 analysis analysis NOUN fnp-5983 68 29 ( ( PUNCT fnp-5983 68 30 pdf pdf NOUN fnp-5983 68 31 ) ) PUNCT fnp-5983 68 32 references reference NOUN fnp-5983 68 33 1 1 NUM fnp-5983 68 34 . . PUNCT fnp-5983 69 1 brat brat PROPN fnp-5983 69 2 dj dj PROPN fnp-5983 69 3 , , PUNCT fnp-5983 69 4 solomon solomon PROPN fnp-5983 69 5 da da PROPN fnp-5983 69 6 , , PUNCT fnp-5983 69 7 rosenblum rosenblum PROPN fnp-5983 69 8 mk mk PROPN fnp-5983 69 9 , , PUNCT fnp-5983 69 10 aldape aldape PROPN fnp-5983 69 11 kd kd PROPN fnp-5983 69 12 , , PUNCT fnp-5983 69 13 idbaih idbaih VERB fnp-5983 69 14 a a DET fnp-5983 69 15 , , PUNCT fnp-5983 69 16 kool kool NOUN fnp-5983 69 17 m m PROPN fnp-5983 69 18 , , PUNCT fnp-5983 69 19 et et PROPN fnp-5983 69 20 al al PROPN fnp-5983 69 21 . . PROPN fnp-5983 69 22 astroblastoma astroblastoma PROPN fnp-5983 69 23 , , PUNCT fnp-5983 69 24 mn1 mn1 PROPN fnp-5983 69 25 - - PUNCT fnp-5983 69 26 altered alter VERB fnp-5983 69 27 . . PUNCT fnp-5983 70 1 in in ADP fnp-5983 70 2 : : PUNCT fnp-5983 70 3 who who PRON fnp-5983 70 4 classification classification VERB fnp-5983 70 5 tumours tumours PROPN fnp-5983 70 6 editorial editorial PROPN fnp-5983 70 7 board board PROPN fnp-5983 70 8 . . PUNCT fnp-5983 71 1 central central ADJ fnp-5983 71 2 nervous nervous ADJ fnp-5983 71 3 system system NOUN fnp-5983 71 4 tumours tumour VERB fnp-5983 71 5 . . PUNCT fnp-5983 72 1 lyon lyon PROPN fnp-5983 72 2 ( ( PUNCT fnp-5983 72 3 france france PROPN fnp-5983 72 4 ): ): PUNCT fnp-5983 72 5 international international ADJ fnp-5983 72 6 agency agency NOUN fnp-5983 72 7 for for ADP fnp-5983 72 8 research research NOUN fnp-5983 72 9 on on ADP fnp-5983 72 10 cancer cancer NOUN fnp-5983 72 11 ; ; PUNCT fnp-5983 72 12 2021 2021 NUM fnp-5983 72 13 . . PUNCT fnp-5983 73 1 ( ( PUNCT fnp-5983 73 2 who who PRON fnp-5983 73 3 classification classification NOUN fnp-5983 73 4 of of ADP fnp-5983 73 5 tumours tumours PROPN fnp-5983 73 6 series series NOUN fnp-5983 73 7 , , PUNCT fnp-5983 73 8 5th 5th ADJ fnp-5983 73 9 ed ed NOUN fnp-5983 73 10 . . PUNCT fnp-5983 73 11 ; ; PUNCT fnp-5983 74 1 vol vol NOUN fnp-5983 74 2 . . PROPN fnp-5983 74 3 6 6 NUM fnp-5983 74 4 ) ) PUNCT fnp-5983 74 5 . . PUNCT fnp-5983 75 1 https://publications.iarc.fr/601 https://publications.iarc.fr/601 X fnp-5983 76 1 2 2 X fnp-5983 76 2 . . X fnp-5983 76 3 sturm sturm PROPN fnp-5983 76 4 d d PROPN fnp-5983 76 5 , , PUNCT fnp-5983 76 6 orr orr PROPN fnp-5983 76 7 ba ba PROPN fnp-5983 76 8 , , PUNCT fnp-5983 76 9 toprak toprak NOUN fnp-5983 76 10 uh uh INTJ fnp-5983 76 11 , , PUNCT fnp-5983 76 12 hovestadt hovestadt ADJ fnp-5983 76 13 v v NOUN fnp-5983 76 14 , , PUNCT fnp-5983 76 15 jones jones PROPN fnp-5983 76 16 dtw dtw PROPN fnp-5983 76 17 , , PUNCT fnp-5983 76 18 capper capper NOUN fnp-5983 76 19 d d PROPN fnp-5983 76 20 , , PUNCT fnp-5983 76 21 et et PROPN fnp-5983 76 22 al al PROPN fnp-5983 76 23 . . PUNCT fnp-5983 77 1 new new ADJ fnp-5983 77 2 brain brain NOUN fnp-5983 77 3 tumor tumor NOUN fnp-5983 77 4 entities entity NOUN fnp-5983 77 5 emerge emerge VERB fnp-5983 77 6 from from ADP fnp-5983 77 7 molecular molecular ADJ fnp-5983 77 8 classification classification NOUN fnp-5983 77 9 of of ADP fnp-5983 77 10 cns cns NOUN fnp-5983 77 11 - - PUNCT fnp-5983 77 12 pnets pnet NOUN fnp-5983 77 13 . . PUNCT fnp-5983 78 1 cell cell NOUN fnp-5983 78 2 . . PUNCT fnp-5983 79 1 2016;164:1060–72 2016;164:1060–72 NUM fnp-5983 79 2 . . PUNCT fnp-5983 80 1 https://doi.org/10.1016/j.cell.2016.01.015 https://doi.org/10.1016/j.cell.2016.01.015 PROPN fnp-5983 80 2 3 3 NUM fnp-5983 80 3 . . PUNCT fnp-5983 80 4 lucas lucas PROPN fnp-5983 80 5 c c PROPN fnp-5983 80 6 - - PUNCT fnp-5983 80 7 hg hg NOUN fnp-5983 80 8 , , PUNCT fnp-5983 80 9 gupta gupta PROPN fnp-5983 80 10 r r PROPN fnp-5983 80 11 , , PUNCT fnp-5983 80 12 wu wu PROPN fnp-5983 80 13 j j PROPN fnp-5983 80 14 , , PUNCT fnp-5983 80 15 shah shah PROPN fnp-5983 80 16 k k PROPN fnp-5983 80 17 , , PUNCT fnp-5983 80 18 ravindranathan ravindranathan PROPN fnp-5983 80 19 a a PROPN fnp-5983 80 20 , , PUNCT fnp-5983 80 21 barreto barreto PROPN fnp-5983 80 22 j j PROPN fnp-5983 80 23 , , PUNCT fnp-5983 80 24 et et PROPN fnp-5983 80 25 al al PROPN fnp-5983 80 26 . . PUNCT fnp-5983 80 27 ewsr1 ewsr1 PROPN fnp-5983 80 28 - - PUNCT fnp-5983 80 29 bend2 bend2 NOUN fnp-5983 80 30 fusion fusion NOUN fnp-5983 80 31 defines define VERB fnp-5983 80 32 an an DET fnp-5983 80 33 epigenetically epigenetically ADV fnp-5983 80 34 distinct distinct ADJ fnp-5983 80 35 subtype subtype NOUN fnp-5983 80 36 of of ADP fnp-5983 80 37 astroblastoma astroblastoma NOUN fnp-5983 80 38 . . PUNCT fnp-5983 81 1 acta acta PROPN fnp-5983 81 2 neuropathol neuropathol PROPN fnp-5983 81 3 . . PUNCT fnp-5983 82 1 2022;143:109–13 2022;143:109–13 X fnp-5983 82 2 . . NOUN fnp-5983 82 3 https://doi.org/10.1007/s00401-021-02388-y https://doi.org/10.1007/s00401-021-02388-y PROPN fnp-5983 82 4 4 4 NUM fnp-5983 82 5 . . PUNCT fnp-5983 83 1 tsutsui tsutsui PROPN fnp-5983 83 2 t t PROPN fnp-5983 83 3 , , PUNCT fnp-5983 83 4 arakawa arakawa PROPN fnp-5983 83 5 y y PROPN fnp-5983 83 6 , , PUNCT fnp-5983 83 7 makino makino PROPN fnp-5983 83 8 y y PROPN fnp-5983 83 9 , , PUNCT fnp-5983 83 10 kataoka kataoka PROPN fnp-5983 83 11 h h PROPN fnp-5983 83 12 , , PUNCT fnp-5983 83 13 mineharu mineharu PROPN fnp-5983 83 14 y y PROPN fnp-5983 83 15 , , PUNCT fnp-5983 83 16 naito naito PROPN fnp-5983 83 17 k k PROPN fnp-5983 83 18 , , PUNCT fnp-5983 83 19 et et PROPN fnp-5983 83 20 al al PROPN fnp-5983 83 21 . . PUNCT fnp-5983 84 1 spinal spinal PROPN fnp-5983 84 2 cord cord NOUN fnp-5983 84 3 astroblastoma astroblastoma NOUN fnp-5983 84 4 with with ADP fnp-5983 84 5 ewsr1 ewsr1 ADJ fnp-5983 84 6 - - PUNCT fnp-5983 84 7 bend2 bend2 NOUN fnp-5983 84 8 fusion fusion NOUN fnp-5983 84 9 classified classify VERB fnp-5983 84 10 as as ADP fnp-5983 84 11 hgnet hgnet NOUN fnp-5983 84 12 - - PUNCT fnp-5983 84 13 mn1 mn1 NOUN fnp-5983 84 14 by by ADP fnp-5983 84 15 methylation methylation NOUN fnp-5983 84 16 classification classification NOUN fnp-5983 84 17 : : PUNCT fnp-5983 84 18 a a DET fnp-5983 84 19 case case NOUN fnp-5983 84 20 report report NOUN fnp-5983 84 21 . . PUNCT fnp-5983 85 1 brain brain NOUN fnp-5983 85 2 tumor tumor NOUN fnp-5983 85 3 pathol pathol NOUN fnp-5983 85 4 . . PUNCT fnp-5983 86 1 2021;38:283–9 2021;38:283–9 X fnp-5983 86 2 . . PUNCT fnp-5983 87 1 https://doi.org/10.1007/s10014-021-00412-3 https://doi.org/10.1007/s10014-021-00412-3 NUM fnp-5983 87 2 5 5 NUM fnp-5983 87 3 . . PUNCT fnp-5983 87 4 baroni baroni PROPN fnp-5983 87 5 lv lv PROPN fnp-5983 87 6 , , PUNCT fnp-5983 87 7 rugilo rugilo PROPN fnp-5983 87 8 c c NOUN fnp-5983 87 9 , , PUNCT fnp-5983 87 10 lubieniecki lubieniecki NOUN fnp-5983 87 11 f f NOUN fnp-5983 87 12 , , PUNCT fnp-5983 87 13 sampor sampor ADP fnp-5983 87 14 c c NOUN fnp-5983 87 15 , , PUNCT fnp-5983 87 16 freytes freyte VERB fnp-5983 87 17 c c PROPN fnp-5983 87 18 , , PUNCT fnp-5983 87 19 nobre nobre PROPN fnp-5983 87 20 l l NOUN fnp-5983 87 21 , , PUNCT fnp-5983 87 22 et et PROPN fnp-5983 87 23 al al PROPN fnp-5983 87 24 . . PUNCT fnp-5983 88 1 treatment treatment NOUN fnp-5983 88 2 response response NOUN fnp-5983 88 3 of of ADP fnp-5983 88 4 cns cns PROPN fnp-5983 88 5 high high ADJ fnp-5983 88 6 - - PUNCT fnp-5983 88 7 grade grade NOUN fnp-5983 88 8 neuroepithelial neuroepithelial ADJ fnp-5983 88 9 tumors tumor NOUN fnp-5983 88 10 with with ADP fnp-5983 88 11 mn1 mn1 PROPN fnp-5983 88 12 alteration alteration NOUN fnp-5983 88 13 . . PUNCT fnp-5983 89 1 pediatr pediatr ADJ fnp-5983 89 2 blood blood NOUN fnp-5983 89 3 cancer cancer NOUN fnp-5983 89 4 . . PUNCT fnp-5983 90 1 2020;67 2020;67 NUM fnp-5983 90 2 : : PUNCT fnp-5983 90 3 e28627 e28627 NOUN fnp-5983 90 4 . . PUNCT fnp-5983 91 1 https://doi.org/10.1002/pbc.28627 https://doi.org/10.1002/pbc.28627 PROPN fnp-5983 91 2 6 6 NUM fnp-5983 91 3 . . PUNCT fnp-5983 92 1 burford burford PROPN fnp-5983 92 2 a a PROPN fnp-5983 92 3 , , PUNCT fnp-5983 92 4 mackay mackay PROPN fnp-5983 92 5 a a PROPN fnp-5983 92 6 , , PUNCT fnp-5983 92 7 popov popov PROPN fnp-5983 92 8 s s PROPN fnp-5983 92 9 , , PUNCT fnp-5983 92 10 vinci vinci PROPN fnp-5983 92 11 m m PROPN fnp-5983 92 12 , , PUNCT fnp-5983 92 13 carvalho carvalho PROPN fnp-5983 92 14 d d PROPN fnp-5983 92 15 , , PUNCT fnp-5983 92 16 clarke clarke PROPN fnp-5983 92 17 m m PROPN fnp-5983 92 18 , , PUNCT fnp-5983 92 19 et et PROPN fnp-5983 92 20 al al PROPN fnp-5983 92 21 . . PUNCT fnp-5983 93 1 the the DET fnp-5983 93 2 ten ten NUM fnp-5983 93 3 - - PUNCT fnp-5983 93 4 year year NOUN fnp-5983 93 5 evolutionary evolutionary ADJ fnp-5983 93 6 trajectory trajectory NOUN fnp-5983 93 7 of of ADP fnp-5983 93 8 a a DET fnp-5983 93 9 highly highly ADV fnp-5983 93 10 recurrent recurrent ADJ fnp-5983 93 11 paediatric paediatric ADJ fnp-5983 93 12 high high ADJ fnp-5983 93 13 grade grade NOUN fnp-5983 93 14 neuroepithelial neuroepithelial ADJ fnp-5983 93 15 tumour tumour NOUN fnp-5983 93 16 with with ADP fnp-5983 93 17 mn1 mn1 PROPN fnp-5983 93 18 : : PUNCT fnp-5983 93 19 bend2 bend2 NOUN fnp-5983 93 20 fusion fusion NOUN fnp-5983 93 21 . . PUNCT fnp-5983 94 1 sci sci PROPN fnp-5983 94 2 rep rep PROPN fnp-5983 94 3 . . PROPN fnp-5983 94 4 2018;8:1032 2018;8:1032 NUM fnp-5983 94 5 . . PUNCT fnp-5983 95 1 https://doi.org/10.1038/s41598-018-19389-9 https://doi.org/10.1038/s41598-018-19389-9 NUM fnp-5983 95 2 7 7 NUM fnp-5983 95 3 . . PUNCT fnp-5983 96 1 chou chou PROPN fnp-5983 96 2 s s PROPN fnp-5983 96 3 , , PUNCT fnp-5983 96 4 nael nael PROPN fnp-5983 96 5 a a X fnp-5983 96 6 , , PUNCT fnp-5983 96 7 crawford crawford PROPN fnp-5983 96 8 jr jr PROPN fnp-5983 96 9 , , PUNCT fnp-5983 96 10 sato sato NOUN fnp-5983 96 11 m. m. NOUN fnp-5983 96 12 a a DET fnp-5983 96 13 rare rare ADJ fnp-5983 96 14 case case NOUN fnp-5983 96 15 of of ADP fnp-5983 96 16 pediatric pediatric ADJ fnp-5983 96 17 mn1 mn1 PROPN fnp-5983 96 18 - - PUNCT fnp-5983 96 19 altered alter VERB fnp-5983 96 20 astroblastoma astroblastoma NOUN fnp-5983 96 21 with with ADP fnp-5983 96 22 concomitant concomitant PROPN fnp-5983 96 23 atm atm PROPN fnp-5983 96 24 germline germline NOUN fnp-5983 96 25 mutation mutation NOUN fnp-5983 96 26 . . PUNCT fnp-5983 97 1 pediatr pediatr ADJ fnp-5983 97 2 blood blood NOUN fnp-5983 97 3 cancer cancer NOUN fnp-5983 97 4 . . PUNCT fnp-5983 98 1 2023;70 2023;70 NUM fnp-5983 98 2 : : PUNCT fnp-5983 98 3 e30502 e30502 PROPN fnp-5983 98 4 . . PUNCT fnp-5983 99 1 https://doi.org/10.1002/pbc.30502 https://doi.org/10.1002/pbc.30502 PROPN fnp-5983 99 2 8 8 NUM fnp-5983 99 3 . . PUNCT fnp-5983 100 1 cuoco cuoco PROPN fnp-5983 100 2 ja ja PROPN fnp-5983 100 3 , , PUNCT fnp-5983 100 4 williams williams PROPN fnp-5983 100 5 s s PROPN fnp-5983 100 6 , , PUNCT fnp-5983 100 7 klein klein PROPN fnp-5983 100 8 bj bj PROPN fnp-5983 100 9 , , PUNCT fnp-5983 100 10 borowicz borowicz PROPN fnp-5983 100 11 vm vm PROPN fnp-5983 100 12 , , PUNCT fnp-5983 100 13 ho ho PROPN fnp-5983 100 14 h h PROPN fnp-5983 100 15 , , PUNCT fnp-5983 100 16 stump stump NOUN fnp-5983 100 17 ms ms NOUN fnp-5983 100 18 , , PUNCT fnp-5983 100 19 et et PROPN fnp-5983 100 20 al al PROPN fnp-5983 100 21 . . PROPN fnp-5983 100 22 astroblastoma astroblastoma PROPN fnp-5983 100 23 with with ADP fnp-5983 100 24 a a DET fnp-5983 100 25 novel novel ADJ fnp-5983 100 26 yap1::bend2 yap1::bend2 NOUN fnp-5983 100 27 fusion fusion NOUN fnp-5983 100 28 : : PUNCT fnp-5983 100 29 a a DET fnp-5983 100 30 case case NOUN fnp-5983 100 31 report report NOUN fnp-5983 100 32 . . PUNCT fnp-5983 101 1 j j PROPN fnp-5983 101 2 pediatr pediatr PROPN fnp-5983 101 3 hematol hematol PROPN fnp-5983 101 4 oncol oncol ADJ fnp-5983 101 5 . . PUNCT fnp-5983 102 1 2024;46 2024;46 NUM fnp-5983 102 2 : : PUNCT fnp-5983 102 3 e313–6 e313–6 NOUN fnp-5983 102 4 . . PUNCT fnp-5983 103 1 https://doi.org/10.1097/mph.0000000000002885 https://doi.org/10.1097/mph.0000000000002885 PROPN fnp-5983 103 2 9 9 NUM fnp-5983 103 3 . . PUNCT fnp-5983 104 1 frederico frederico PROPN fnp-5983 104 2 sc sc PROPN fnp-5983 104 3 , , PUNCT fnp-5983 104 4 vera vera NOUN fnp-5983 104 5 e e NOUN fnp-5983 104 6 , , PUNCT fnp-5983 104 7 abdullaev abdullaev PROPN fnp-5983 104 8 z z PROPN fnp-5983 104 9 , , PUNCT fnp-5983 104 10 acquaye acquaye VERB fnp-5983 104 11 a a DET fnp-5983 104 12 , , PUNCT fnp-5983 104 13 aldape aldape NOUN fnp-5983 104 14 k k PROPN fnp-5983 104 15 , , PUNCT fnp-5983 104 16 boris boris PROPN fnp-5983 104 17 l l PROPN fnp-5983 104 18 , , PUNCT fnp-5983 104 19 et et PROPN fnp-5983 104 20 al al PROPN fnp-5983 104 21 . . PROPN fnp-5983 104 22 heterogeneous heterogeneous ADJ fnp-5983 104 23 clinicopathological clinicopathological ADJ fnp-5983 104 24 findings finding NOUN fnp-5983 104 25 and and CCONJ fnp-5983 104 26 patient patient NOUN fnp-5983 104 27 - - PUNCT fnp-5983 104 28 reported report VERB fnp-5983 104 29 outcomes outcome NOUN fnp-5983 104 30 in in ADP fnp-5983 104 31 adults adult NOUN fnp-5983 104 32 with with ADP fnp-5983 104 33 mn1 mn1 NOUN fnp-5983 104 34 - - PUNCT fnp-5983 104 35 altered alter VERB fnp-5983 104 36 cns cns NOUN fnp-5983 104 37 tumors tumor NOUN fnp-5983 104 38 : : PUNCT fnp-5983 104 39 a a DET fnp-5983 104 40 case case NOUN fnp-5983 104 41 report report NOUN fnp-5983 104 42 and and CCONJ fnp-5983 104 43 systematic systematic ADJ fnp-5983 104 44 literature literature PROPN fnp-5983 104 45 review review PROPN fnp-5983 104 46 . . PUNCT fnp-5983 105 1 front front ADJ fnp-5983 105 2 oncol oncol ADJ fnp-5983 105 3 . . PUNCT fnp-5983 106 1 2023;13:1099618 2023;13:1099618 NUM fnp-5983 106 2 . . PUNCT fnp-5983 107 1 https://doi.org/10.3389/fonc.2023.1099618 https://doi.org/10.3389/fonc.2023.1099618 PROPN fnp-5983 107 2 10 10 NUM fnp-5983 107 3 . . PUNCT fnp-5983 108 1 fudaba fudaba PROPN fnp-5983 108 2 h h PROPN fnp-5983 108 3 , , PUNCT fnp-5983 108 4 momii momii PROPN fnp-5983 108 5 y y PROPN fnp-5983 108 6 , , PUNCT fnp-5983 108 7 kawasaki kawasaki PROPN fnp-5983 108 8 y y PROPN fnp-5983 108 9 , , PUNCT fnp-5983 108 10 goto goto ADJ fnp-5983 108 11 h h NOUN fnp-5983 108 12 , , PUNCT fnp-5983 108 13 nobusawa nobusawa PROPN fnp-5983 108 14 s s PROPN fnp-5983 108 15 , , PUNCT fnp-5983 108 16 fujiki fujiki ADJ fnp-5983 108 17 m. m. NOUN fnp-5983 108 18 well well ADV fnp-5983 108 19 - - PUNCT fnp-5983 108 20 differentiated differentiate VERB fnp-5983 108 21 astroblastoma astroblastoma NOUN fnp-5983 108 22 with with ADP fnp-5983 108 23 both both CCONJ fnp-5983 108 24 focal focal ADJ fnp-5983 108 25 anaplastic anaplastic ADJ fnp-5983 108 26 features feature NOUN fnp-5983 108 27 and and CCONJ fnp-5983 108 28 a a DET fnp-5983 108 29 meningioma meningioma NOUN fnp-5983 108 30 1 1 NUM fnp-5983 108 31 gene gene NOUN fnp-5983 108 32 alteration alteration NOUN fnp-5983 108 33 . . PUNCT fnp-5983 109 1 nmc nmc PROPN fnp-5983 109 2 case case NOUN fnp-5983 109 3 rep rep PROPN fnp-5983 109 4 j. j. PROPN fnp-5983 109 5 2020;7:205–10 2020;7:205–10 PROPN fnp-5983 109 6 . . PUNCT fnp-5983 110 1 https://doi.org/10.2176/nmccrj.cr.2020-0028 https://doi.org/10.2176/nmccrj.cr.2020-0028 ADJ fnp-5983 110 2 11 11 NUM fnp-5983 110 3 . . PUNCT fnp-5983 110 4 hirose hirose PROPN fnp-5983 110 5 t t PROPN fnp-5983 110 6 , , PUNCT fnp-5983 110 7 nobusawa nobusawa PROPN fnp-5983 110 8 s s PROPN fnp-5983 110 9 , , PUNCT fnp-5983 110 10 sugiyama sugiyama NOUN fnp-5983 110 11 k k PROPN fnp-5983 110 12 , , PUNCT fnp-5983 110 13 amatya amatya PROPN fnp-5983 110 14 vj vj PROPN fnp-5983 110 15 , , PUNCT fnp-5983 110 16 fujimoto fujimoto PROPN fnp-5983 110 17 n n CCONJ fnp-5983 110 18 , , PUNCT fnp-5983 110 19 sasaki sasaki PROPN fnp-5983 110 20 a a PROPN fnp-5983 110 21 , , PUNCT fnp-5983 110 22 et et PROPN fnp-5983 110 23 al al PROPN fnp-5983 110 24 . . PUNCT fnp-5983 110 25 astroblastoma astroblastoma PROPN fnp-5983 110 26 : : PUNCT fnp-5983 110 27 a a DET fnp-5983 110 28 distinct distinct ADJ fnp-5983 110 29 tumor tumor NOUN fnp-5983 110 30 entity entity NOUN fnp-5983 110 31 characterized characterize VERB fnp-5983 110 32 by by ADP fnp-5983 110 33 alterations alteration NOUN fnp-5983 110 34 of of ADP fnp-5983 110 35 the the DET fnp-5983 110 36 x x NOUN fnp-5983 110 37 chromosome chromosome NOUN fnp-5983 110 38 and and CCONJ fnp-5983 110 39 mn1 mn1 PROPN fnp-5983 110 40 rearrangement rearrangement NOUN fnp-5983 110 41 . . PUNCT fnp-5983 111 1 brain brain NOUN fnp-5983 111 2 pathol pathol NOUN fnp-5983 111 3 . . PUNCT fnp-5983 112 1 2018;28:684–94 2018;28:684–94 X fnp-5983 112 2 . . PUNCT fnp-5983 113 1 https://doi.org/10.1111/bpa.12565 https://doi.org/10.1111/bpa.12565 PROPN fnp-5983 113 2 12 12 NUM fnp-5983 113 3 . . PUNCT fnp-5983 114 1 łastowska łastowska PROPN fnp-5983 114 2 m m PROPN fnp-5983 114 3 , , PUNCT fnp-5983 114 4 trubicka trubicka PROPN fnp-5983 114 5 j j PROPN fnp-5983 114 6 , , PUNCT fnp-5983 114 7 sobocińska sobocińska PROPN fnp-5983 114 8 a a X fnp-5983 114 9 , , PUNCT fnp-5983 114 10 wojtas wojtas PROPN fnp-5983 114 11 b b PROPN fnp-5983 114 12 , , PUNCT fnp-5983 114 13 niemira niemira PROPN fnp-5983 114 14 m m PROPN fnp-5983 114 15 , , PUNCT fnp-5983 114 16 szałkowska szałkowska VERB fnp-5983 114 17 a a PRON fnp-5983 114 18 , , PUNCT fnp-5983 114 19 et et PROPN fnp-5983 114 20 al al PROPN fnp-5983 114 21 . . PROPN fnp-5983 115 1 molecular molecular ADJ fnp-5983 115 2 identification identification NOUN fnp-5983 115 3 of of ADP fnp-5983 115 4 cns cns PROPN fnp-5983 115 5 nb nb PROPN fnp-5983 115 6 - - PUNCT fnp-5983 115 7 foxr2 foxr2 PROPN fnp-5983 115 8 , , PUNCT fnp-5983 115 9 cns cns PROPN fnp-5983 115 10 eft eft PROPN fnp-5983 115 11 - - PUNCT fnp-5983 115 12 cic cic PROPN fnp-5983 115 13 , , PUNCT fnp-5983 115 14 cns cns PROPN fnp-5983 115 15 hgnet hgnet PROPN fnp-5983 115 16 - - PUNCT fnp-5983 115 17 mn1 mn1 PROPN fnp-5983 115 18 and and CCONJ fnp-5983 115 19 cns cns PROPN fnp-5983 115 20 hgnet hgnet NOUN fnp-5983 115 21 - - PUNCT fnp-5983 115 22 bcor bcor NOUN fnp-5983 115 23 pediatric pediatric ADJ fnp-5983 115 24 brain brain NOUN fnp-5983 115 25 tumors tumor NOUN fnp-5983 115 26 using use VERB fnp-5983 115 27 tumor tumor NOUN fnp-5983 115 28 - - PUNCT fnp-5983 115 29 specific specific ADJ fnp-5983 115 30 signature signature NOUN fnp-5983 115 31 genes gene NOUN fnp-5983 115 32 . . PUNCT fnp-5983 116 1 acta acta PROPN fnp-5983 116 2 neuropathol neuropathol PROPN fnp-5983 116 3 commun commun PROPN fnp-5983 116 4 . . PUNCT fnp-5983 117 1 2020;8:105 2020;8:105 NOUN fnp-5983 117 2 . . PUNCT fnp-5983 118 1 https://doi.org/10.1186/s40478-020-00984-9 https://doi.org/10.1186/s40478-020-00984-9 ADJ fnp-5983 118 2 13 13 NUM fnp-5983 118 3 . . PUNCT fnp-5983 119 1 lehman lehman PROPN fnp-5983 119 2 nl nl PROPN fnp-5983 119 3 , , PUNCT fnp-5983 119 4 usubalieva usubalieva VERB fnp-5983 119 5 a a PRON fnp-5983 119 6 , , PUNCT fnp-5983 119 7 lin lin PROPN fnp-5983 119 8 t t PROPN fnp-5983 119 9 , , PUNCT fnp-5983 119 10 allen allen PROPN fnp-5983 119 11 sj sj PROPN fnp-5983 119 12 , , PUNCT fnp-5983 119 13 tran tran PROPN fnp-5983 119 14 qt qt PROPN fnp-5983 119 15 , , PUNCT fnp-5983 119 16 mobley mobley PROPN fnp-5983 119 17 bc bc PROPN fnp-5983 119 18 , , PUNCT fnp-5983 119 19 et et PROPN fnp-5983 119 20 al al PROPN fnp-5983 119 21 . . PUNCT fnp-5983 120 1 genomic genomic ADJ fnp-5983 120 2 analysis analysis NOUN fnp-5983 120 3 demonstrates demonstrate VERB fnp-5983 120 4 that that SCONJ fnp-5983 120 5 histologically histologically ADV fnp-5983 120 6 - - PUNCT fnp-5983 120 7 defined define VERB fnp-5983 120 8 astroblastomas astroblastoma NOUN fnp-5983 120 9 are be AUX fnp-5983 120 10 molecularly molecularly ADV fnp-5983 120 11 heterogeneous heterogeneous ADJ fnp-5983 120 12 and and CCONJ fnp-5983 120 13 that that SCONJ fnp-5983 120 14 tumors tumor NOUN fnp-5983 120 15 with with ADP fnp-5983 120 16 mn1 mn1 PROPN fnp-5983 120 17 rearrangement rearrangement NOUN fnp-5983 120 18 exhibit exhibit VERB fnp-5983 120 19 the the DET fnp-5983 120 20 most most ADV fnp-5983 120 21 favorable favorable ADJ fnp-5983 120 22 prognosis prognosis NOUN fnp-5983 120 23 . . PUNCT fnp-5983 121 1 acta acta PROPN fnp-5983 121 2 neuropathol neuropathol PROPN fnp-5983 121 3 commun commun PROPN fnp-5983 121 4 . . PUNCT fnp-5983 122 1 2019;7:42 2019;7:42 ADJ fnp-5983 122 2 . . PUNCT fnp-5983 123 1 https://doi.org/10.1186/s40478-019-0689-3 https://doi.org/10.1186/s40478-019-0689-3 NUM fnp-5983 123 2 14 14 NUM fnp-5983 123 3 . . PUNCT fnp-5983 124 1 mhatre mhatre NOUN fnp-5983 124 2 r r NOUN fnp-5983 124 3 , , PUNCT fnp-5983 124 4 sugur sugur PROPN fnp-5983 124 5 hs hs PROPN fnp-5983 124 6 , , PUNCT fnp-5983 124 7 nandeesh nandeesh NOUN fnp-5983 124 8 bn bn NOUN fnp-5983 124 9 , , PUNCT fnp-5983 124 10 chickabasaviah chickabasaviah PROPN fnp-5983 124 11 y y PROPN fnp-5983 124 12 , , PUNCT fnp-5983 124 13 saini saini PROPN fnp-5983 124 14 j j PROPN fnp-5983 124 15 , , PUNCT fnp-5983 124 16 santosh santosh PROPN fnp-5983 124 17 v. v. ADP fnp-5983 124 18 mn1 mn1 PROPN fnp-5983 124 19 rearrangement rearrangement NOUN fnp-5983 124 20 in in ADP fnp-5983 124 21 astroblastoma astroblastoma NOUN fnp-5983 124 22 : : PUNCT fnp-5983 124 23 study study NOUN fnp-5983 124 24 of of ADP fnp-5983 124 25 eight eight NUM fnp-5983 124 26 cases case NOUN fnp-5983 124 27 and and CCONJ fnp-5983 124 28 review review NOUN fnp-5983 124 29 of of ADP fnp-5983 124 30 literature literature NOUN fnp-5983 124 31 . . PUNCT fnp-5983 125 1 brain brain NOUN fnp-5983 125 2 tumor tumor NOUN fnp-5983 125 3 pathol pathol NOUN fnp-5983 125 4 . . PUNCT fnp-5983 126 1 2019;36:112 2019;36:112 NUM fnp-5983 126 2 - - SYM fnp-5983 126 3 20 20 NUM fnp-5983 126 4 . . PUNCT fnp-5983 127 1 https://doi.org/10.1007/s10014-019-00346-x https://doi.org/10.1007/s10014-019-00346-x NOUN fnp-5983 127 2 15 15 NUM fnp-5983 127 3 . . PUNCT fnp-5983 128 1 mugge mugge PROPN fnp-5983 128 2 l l PROPN fnp-5983 128 3 , , PUNCT fnp-5983 128 4 dang dang PROPN fnp-5983 128 5 dd dd PROPN fnp-5983 128 6 , , PUNCT fnp-5983 128 7 stabingas stabingas PROPN fnp-5983 128 8 k k PROPN fnp-5983 128 9 , , PUNCT fnp-5983 128 10 keating keate VERB fnp-5983 128 11 g g PROPN fnp-5983 128 12 , , PUNCT fnp-5983 128 13 rossi rossi PROPN fnp-5983 128 14 c c X fnp-5983 128 15 , , PUNCT fnp-5983 128 16 keating keating PROPN fnp-5983 128 17 r. r. PROPN fnp-5983 128 18 mn1 mn1 PROPN fnp-5983 128 19 altered alter VERB fnp-5983 128 20 astroblastoma astroblastoma NOUN fnp-5983 128 21 with with ADP fnp-5983 128 22 apc apc PROPN fnp-5983 128 23 and and CCONJ fnp-5983 128 24 lrp1b lrp1b PROPN fnp-5983 128 25 gene gene NOUN fnp-5983 128 26 mutations mutation NOUN fnp-5983 128 27 : : PUNCT fnp-5983 128 28 a a DET fnp-5983 128 29 unique unique ADJ fnp-5983 128 30 variant variant NOUN fnp-5983 128 31 in in ADP fnp-5983 128 32 the the DET fnp-5983 128 33 cervical cervical ADJ fnp-5983 128 34 spine spine NOUN fnp-5983 128 35 of of ADP fnp-5983 128 36 a a DET fnp-5983 128 37 pediatric pediatric ADJ fnp-5983 128 38 patient patient NOUN fnp-5983 128 39 . . PUNCT fnp-5983 129 1 childs child VERB fnp-5983 129 2 nerv nerv PROPN fnp-5983 129 3 syst syst PROPN fnp-5983 129 4 . . PUNCT fnp-5983 130 1 2023;39:1309–15 2023;39:1309–15 NUM fnp-5983 130 2 . . PUNCT fnp-5983 131 1 https://doi.org/10.1007/s00381-022-05795-y https://doi.org/10.1007/s00381-022-05795-y PRON fnp-5983 131 2 16 16 NUM fnp-5983 131 3 . . PUNCT fnp-5983 131 4 panda panda PROPN fnp-5983 131 5 ak ak PROPN fnp-5983 131 6 , , PUNCT fnp-5983 131 7 das das PROPN fnp-5983 131 8 s s PROPN fnp-5983 131 9 , , PUNCT fnp-5983 131 10 singh singh PROPN fnp-5983 131 11 a a X fnp-5983 131 12 , , PUNCT fnp-5983 131 13 vaishya vaishya PROPN fnp-5983 131 14 s s PROPN fnp-5983 131 15 , , PUNCT fnp-5983 131 16 gupta gupta PROPN fnp-5983 131 17 rk rk PRON fnp-5983 131 18 , , PUNCT fnp-5983 131 19 sharma sharma PROPN fnp-5983 131 20 mc mc PROPN fnp-5983 131 21 , , PUNCT fnp-5983 131 22 et et PROPN fnp-5983 131 23 al al PROPN fnp-5983 131 24 . . PUNCT fnp-5983 132 1 spinal spinal PROPN fnp-5983 132 2 astroblastoma astroblastoma NOUN fnp-5983 132 3 , , PUNCT fnp-5983 132 4 mn1 mn1 PROPN fnp-5983 132 5 altered alter VERB fnp-5983 132 6 in in ADP fnp-5983 132 7 3 3 NUM fnp-5983 132 8 - - PUNCT fnp-5983 132 9 year year NOUN fnp-5983 132 10 - - PUNCT fnp-5983 132 11 old old ADJ fnp-5983 132 12 child child NOUN fnp-5983 132 13 : : PUNCT fnp-5983 132 14 an an DET fnp-5983 132 15 uncommon uncommon ADJ fnp-5983 132 16 tumor tumor NOUN fnp-5983 132 17 at at ADP fnp-5983 132 18 an an DET fnp-5983 132 19 unusual unusual ADJ fnp-5983 132 20 site site NOUN fnp-5983 132 21 . . PUNCT fnp-5983 133 1 neuropathology neuropathology NOUN fnp-5983 133 2 . . PUNCT fnp-5983 134 1 2024;44:314 2024;44:314 NUM fnp-5983 134 2 - - SYM fnp-5983 134 3 8 8 NUM fnp-5983 134 4 . . PUNCT fnp-5983 134 5 https://doi.org/10.1111/neup.12965 https://doi.org/10.1111/neup.12965 NOUN fnp-5983 134 6 17 17 NUM fnp-5983 134 7 . . PUNCT fnp-5983 135 1 petruzzellis petruzzellis PROPN fnp-5983 135 2 g g PROPN fnp-5983 135 3 , , PUNCT fnp-5983 135 4 alessi alessi PROPN fnp-5983 135 5 i i PRON fnp-5983 135 6 , , PUNCT fnp-5983 135 7 colafati colafati PROPN fnp-5983 135 8 gs gs PROPN fnp-5983 135 9 , , PUNCT fnp-5983 135 10 diomedi diomedi PROPN fnp-5983 135 11 - - PUNCT fnp-5983 135 12 camassei camassei PROPN fnp-5983 135 13 f f PROPN fnp-5983 135 14 , , PUNCT fnp-5983 135 15 ciolfi ciolfi VERB fnp-5983 135 16 a a DET fnp-5983 135 17 , , PUNCT fnp-5983 135 18 pedace pedace NOUN fnp-5983 135 19 l l NOUN fnp-5983 135 20 , , PUNCT fnp-5983 135 21 et et PROPN fnp-5983 135 22 al al PROPN fnp-5983 135 23 . . PUNCT fnp-5983 136 1 role role NOUN fnp-5983 136 2 of of ADP fnp-5983 136 3 dna dna PROPN fnp-5983 136 4 methylation methylation NOUN fnp-5983 136 5 profile profile NOUN fnp-5983 136 6 in in ADP fnp-5983 136 7 diagnosing diagnose VERB fnp-5983 136 8 astroblastoma astroblastoma NOUN fnp-5983 136 9 : : PUNCT fnp-5983 136 10 a a DET fnp-5983 136 11 case case NOUN fnp-5983 136 12 report report NOUN fnp-5983 136 13 and and CCONJ fnp-5983 136 14 literature literature PROPN fnp-5983 136 15 review review PROPN fnp-5983 136 16 . . PUNCT fnp-5983 137 1 front front ADJ fnp-5983 137 2 genet genet NOUN fnp-5983 137 3 . . PUNCT fnp-5983 138 1 2019;10:391 2019;10:391 X fnp-5983 138 2 . . PUNCT fnp-5983 139 1 https://doi.org/10.3389/fgene.2019.00391 https://doi.org/10.3389/fgene.2019.00391 PROPN fnp-5983 139 2 18 18 NUM fnp-5983 139 3 . . PUNCT fnp-5983 139 4 price price NOUN fnp-5983 139 5 a a DET fnp-5983 139 6 , , PUNCT fnp-5983 139 7 o’leary o’leary PROPN fnp-5983 139 8 s s PROPN fnp-5983 139 9 , , PUNCT fnp-5983 139 10 malkova malkova PROPN fnp-5983 139 11 k k PROPN fnp-5983 139 12 , , PUNCT fnp-5983 139 13 d’souza d’souza PROPN fnp-5983 139 14 p p NOUN fnp-5983 139 15 , , PUNCT fnp-5983 139 16 ogasawara ogasawara ADJ fnp-5983 139 17 c c NOUN fnp-5983 139 18 , , PUNCT fnp-5983 139 19 felicella felicella NOUN fnp-5983 139 20 mm mm PROPN fnp-5983 139 21 , , PUNCT fnp-5983 139 22 et et PROPN fnp-5983 139 23 al al PROPN fnp-5983 139 24 . . PUNCT fnp-5983 139 25 awake awake ADJ fnp-5983 139 26 resection resection NOUN fnp-5983 139 27 of of ADP fnp-5983 139 28 recurrent recurrent ADJ fnp-5983 139 29 astroblastoma astroblastoma NOUN fnp-5983 139 30 with with ADP fnp-5983 139 31 intraoperative intraoperative ADJ fnp-5983 139 32 5 5 NUM fnp-5983 139 33 - - PUNCT fnp-5983 139 34 ala ala ADV fnp-5983 139 35 - - PUNCT fnp-5983 139 36 induced induce VERB fnp-5983 139 37 fluorescence fluorescence NOUN fnp-5983 139 38 : : PUNCT fnp-5983 139 39 illustrative illustrative ADJ fnp-5983 139 40 case case NOUN fnp-5983 139 41 . . PUNCT fnp-5983 140 1 j j PROPN fnp-5983 140 2 neurosurg neurosurg PROPN fnp-5983 140 3 case case NOUN fnp-5983 140 4 lessons lesson NOUN fnp-5983 140 5 . . PUNCT fnp-5983 141 1 2023;6 2023;6 X fnp-5983 141 2 : : PUNCT fnp-5983 141 3 case23526 case23526 PROPN fnp-5983 141 4 . . PUNCT fnp-5983 142 1 https://doi.org/10.3171/case23526 https://doi.org/10.3171/case23526 NOUN fnp-5983 142 2 19 19 NUM fnp-5983 142 3 . . PUNCT fnp-5983 143 1 rossi rossi PROPN fnp-5983 143 2 s s PROPN fnp-5983 143 3 , , PUNCT fnp-5983 143 4 barresi barresi PROPN fnp-5983 143 5 s s PROPN fnp-5983 143 6 , , PUNCT fnp-5983 143 7 colafati colafati PROPN fnp-5983 143 8 gs gs PROPN fnp-5983 143 9 , , PUNCT fnp-5983 143 10 giovannoni giovannoni PROPN fnp-5983 143 11 i i PROPN fnp-5983 143 12 , , PUNCT fnp-5983 143 13 miele miele PROPN fnp-5983 143 14 e e PROPN fnp-5983 143 15 , , PUNCT fnp-5983 143 16 alesi alesi PROPN fnp-5983 143 17 v v PROPN fnp-5983 143 18 , , PUNCT fnp-5983 143 19 et et PROPN fnp-5983 143 20 al al PROPN fnp-5983 143 21 . . PROPN fnp-5983 143 22 paediatric paediatric ADJ fnp-5983 143 23 astroblastoma astroblastoma NOUN fnp-5983 143 24 - - PUNCT fnp-5983 143 25 like like ADJ fnp-5983 143 26 neuroepithelial neuroepithelial ADJ fnp-5983 143 27 tumour tumour NOUN fnp-5983 143 28 of of ADP fnp-5983 143 29 the the DET fnp-5983 143 30 spinal spinal ADJ fnp-5983 143 31 cord cord NOUN fnp-5983 143 32 with with ADP fnp-5983 143 33 a a DET fnp-5983 143 34 mamld1 mamld1 ADJ fnp-5983 143 35 - - PUNCT fnp-5983 143 36 bend2 bend2 NOUN fnp-5983 143 37 rearrangement rearrangement NOUN fnp-5983 143 38 . . PUNCT fnp-5983 144 1 neuropathol neuropathol PROPN fnp-5983 144 2 appl appl PROPN fnp-5983 144 3 neurobiol neurobiol PROPN fnp-5983 144 4 . . PUNCT fnp-5983 145 1 2022;48 2022;48 X fnp-5983 145 2 : : PUNCT fnp-5983 145 3 e12814 e12814 NOUN fnp-5983 145 4 . . PUNCT fnp-5983 146 1 https://doi.org/10.1111/nan.12814 https://doi.org/10.1111/nan.12814 PROPN fnp-5983 146 2 20 20 NUM fnp-5983 146 3 . . PUNCT fnp-5983 147 1 sari sari ADJ fnp-5983 147 2 r r PROPN fnp-5983 147 3 , , PUNCT fnp-5983 147 4 altinoz altinoz PROPN fnp-5983 147 5 ma ma PROPN fnp-5983 147 6 , , PUNCT fnp-5983 147 7 ozyar ozyar PROPN fnp-5983 147 8 e e NOUN fnp-5983 147 9 , , PUNCT fnp-5983 147 10 danyeli danyeli INTJ fnp-5983 147 11 ae ae PROPN fnp-5983 147 12 , , PUNCT fnp-5983 147 13 elmaci elmaci NOUN fnp-5983 147 14 i. i. PROPN fnp-5983 147 15 a a DET fnp-5983 147 16 pediatric pediatric ADJ fnp-5983 147 17 cerebral cerebral ADJ fnp-5983 147 18 tumor tumor NOUN fnp-5983 147 19 with with ADP fnp-5983 147 20 mn1 mn1 PROPN fnp-5983 147 21 alteration alteration NOUN fnp-5983 147 22 and and CCONJ fnp-5983 147 23 pathological pathological ADJ fnp-5983 147 24 features feature NOUN fnp-5983 147 25 mimicking mimic VERB fnp-5983 147 26 carcinoma carcinoma NOUN fnp-5983 147 27 metastasis metastasis NOUN fnp-5983 147 28 : : PUNCT fnp-5983 147 29 may may AUX fnp-5983 147 30 the the DET fnp-5983 147 31 terminology terminology NOUN fnp-5983 147 32 “ " PUNCT fnp-5983 147 33 high high ADJ fnp-5983 147 34 grade grade NOUN fnp-5983 147 35 neuroepithelial neuroepithelial ADJ fnp-5983 147 36 tumor tumor NOUN fnp-5983 147 37 with with ADP fnp-5983 147 38 mn1 mn1 PROPN fnp-5983 147 39 alteration alteration NOUN fnp-5983 147 40 ” " PUNCT fnp-5983 147 41 still still ADV fnp-5983 147 42 be be AUX fnp-5983 147 43 relevant relevant ADJ fnp-5983 147 44 ? ? PUNCT fnp-5983 148 1 childs child VERB fnp-5983 148 2 nerv nerv PROPN fnp-5983 148 3 syst syst PROPN fnp-5983 148 4 . . PUNCT fnp-5983 149 1 2021;37:2967–74 2021;37:2967–74 NUM fnp-5983 149 2 . . PUNCT fnp-5983 149 3 https://doi.org/10.1007/s00381-021-05289-3 https://doi.org/10.1007/s00381-021-05289-3 PROPN fnp-5983 149 4 21 21 NUM fnp-5983 149 5 . . PUNCT fnp-5983 149 6 shin shin PROPN fnp-5983 149 7 sa sa PROPN fnp-5983 149 8 , , PUNCT fnp-5983 149 9 ahn ahn PROPN fnp-5983 149 10 b b PROPN fnp-5983 149 11 , , PUNCT fnp-5983 149 12 kim kim PROPN fnp-5983 149 13 s s PROPN fnp-5983 149 14 - - PROPN fnp-5983 149 15 k k PROPN fnp-5983 149 16 , , PUNCT fnp-5983 149 17 kang kang PROPN fnp-5983 149 18 hj hj PROPN fnp-5983 149 19 , , PUNCT fnp-5983 149 20 nobusawa nobusawa PROPN fnp-5983 149 21 s s PROPN fnp-5983 149 22 , , PUNCT fnp-5983 149 23 komori komori PROPN fnp-5983 149 24 t t PROPN fnp-5983 149 25 , , PUNCT fnp-5983 149 26 et et PROPN fnp-5983 149 27 al al PROPN fnp-5983 149 28 . . PUNCT fnp-5983 150 1 brainstem brainstem NOUN fnp-5983 150 2 astroblastoma astroblastoma NOUN fnp-5983 150 3 with with ADP fnp-5983 150 4 mn1 mn1 PROPN fnp-5983 150 5 translocation translocation NOUN fnp-5983 150 6 . . PUNCT fnp-5983 151 1 neuropathology neuropathology NOUN fnp-5983 151 2 . . PUNCT fnp-5983 152 1 2018;38:631–7 2018;38:631–7 NUM fnp-5983 152 2 . . PUNCT fnp-5983 153 1 https://doi.org/10.1111/neup.12514 https://doi.org/10.1111/neup.12514 NOUN fnp-5983 153 2 22 22 NUM fnp-5983 153 3 . . PUNCT fnp-5983 154 1 smith smith PROPN fnp-5983 154 2 - - PUNCT fnp-5983 154 3 cohn cohn PROPN fnp-5983 154 4 ma ma PROPN fnp-5983 154 5 , , PUNCT fnp-5983 154 6 abdullaev abdullaev PROPN fnp-5983 154 7 z z PROPN fnp-5983 154 8 , , PUNCT fnp-5983 154 9 aldape aldape PROPN fnp-5983 154 10 kd kd PROPN fnp-5983 154 11 , , PUNCT fnp-5983 154 12 quezado quezado PROPN fnp-5983 154 13 m m PROPN fnp-5983 154 14 , , PUNCT fnp-5983 154 15 rosenblum rosenblum PROPN fnp-5983 154 16 mk mk PROPN fnp-5983 154 17 , , PUNCT fnp-5983 154 18 vanderbilt vanderbilt PROPN fnp-5983 154 19 cm cm PROPN fnp-5983 154 20 , , PUNCT fnp-5983 154 21 et et PROPN fnp-5983 154 22 al al PROPN fnp-5983 154 23 . . PUNCT fnp-5983 155 1 molecular molecular ADJ fnp-5983 155 2 clarification clarification NOUN fnp-5983 155 3 of of ADP fnp-5983 155 4 brainstem brainstem NOUN fnp-5983 155 5 astroblastoma astroblastoma NOUN fnp-5983 155 6 with with ADP fnp-5983 155 7 ewsr1 ewsr1 ADJ fnp-5983 155 8 - - PUNCT fnp-5983 155 9 bend2 bend2 NOUN fnp-5983 155 10 fusion fusion NOUN fnp-5983 155 11 in in ADP fnp-5983 155 12 a a DET fnp-5983 155 13 38 38 NUM fnp-5983 155 14 - - PUNCT fnp-5983 155 15 year year NOUN fnp-5983 155 16 - - PUNCT fnp-5983 155 17 old old ADJ fnp-5983 155 18 man man NOUN fnp-5983 155 19 . . PUNCT fnp-5983 156 1 free free ADJ fnp-5983 156 2 neuropathol neuropathol NOUN fnp-5983 156 3 . . PUNCT fnp-5983 157 1 2021;2:2–16 2021;2:2–16 NOUN fnp-5983 157 2 . . PUNCT fnp-5983 158 1 https://doi.org/10.17879/freeneuropathology-2021-3334 https://doi.org/10.17879/freeneuropathology-2021-3334 PROPN fnp-5983 158 2 23 23 NUM fnp-5983 158 3 . . PUNCT fnp-5983 159 1 yamasaki yamasaki PROPN fnp-5983 159 2 k k PROPN fnp-5983 159 3 , , PUNCT fnp-5983 159 4 nakano nakano PROPN fnp-5983 159 5 y y PROPN fnp-5983 159 6 , , PUNCT fnp-5983 159 7 nobusawa nobusawa PROPN fnp-5983 159 8 s s PART fnp-5983 159 9 , , PUNCT fnp-5983 159 10 okuhiro okuhiro PROPN fnp-5983 159 11 y y PROPN fnp-5983 159 12 , , PUNCT fnp-5983 159 13 fukushima fukushima PROPN fnp-5983 159 14 h h PROPN fnp-5983 159 15 , , PUNCT fnp-5983 159 16 inoue inoue PROPN fnp-5983 159 17 t t PROPN fnp-5983 159 18 , , PUNCT fnp-5983 159 19 et et PROPN fnp-5983 159 20 al al PROPN fnp-5983 159 21 . . PUNCT fnp-5983 160 1 spinal spinal PROPN fnp-5983 160 2 cord cord NOUN fnp-5983 160 3 astroblastoma astroblastoma NOUN fnp-5983 160 4 with with ADP fnp-5983 160 5 an an DET fnp-5983 160 6 ewsr1 ewsr1 ADJ fnp-5983 160 7 - - PUNCT fnp-5983 160 8 bend2 bend2 NOUN fnp-5983 160 9 fusion fusion NOUN fnp-5983 160 10 classified classify VERB fnp-5983 160 11 as as ADP fnp-5983 160 12 a a DET fnp-5983 160 13 high high ADJ fnp-5983 160 14 - - PUNCT fnp-5983 160 15 grade grade NOUN fnp-5983 160 16 neuroepithelial neuroepithelial ADJ fnp-5983 160 17 tumour tumour NOUN fnp-5983 160 18 with with ADP fnp-5983 160 19 mn1 mn1 PROPN fnp-5983 160 20 alteration alteration NOUN fnp-5983 160 21 . . PUNCT fnp-5983 161 1 neuropathol neuropathol NOUN fnp-5983 161 2 appl appl PROPN fnp-5983 161 3 neurobiol neurobiol PROPN fnp-5983 161 4 . . PUNCT fnp-5983 162 1 2020;46:190–3 2020;46:190–3 NUM fnp-5983 162 2 . . PUNCT fnp-5983 163 1 https://doi.org/10.1111/nan.12593 https://doi.org/10.1111/nan.12593 PROPN fnp-5983 163 2 24 24 NUM fnp-5983 163 3 . . PUNCT fnp-5983 164 1 sun sun PROPN fnp-5983 164 2 d d PROPN fnp-5983 164 3 , , PUNCT fnp-5983 164 4 liu liu PROPN fnp-5983 164 5 j j PROPN fnp-5983 164 6 , , PUNCT fnp-5983 164 7 xiao xiao PROPN fnp-5983 164 8 l l PROPN fnp-5983 164 9 , , PUNCT fnp-5983 164 10 guan guan PROPN fnp-5983 164 11 h. h. PROPN fnp-5983 164 12 recurrent recurrent VERB fnp-5983 164 13 high high ADJ fnp-5983 164 14 - - PUNCT fnp-5983 164 15 grade grade NOUN fnp-5983 164 16 astroblastoma astroblastoma NOUN fnp-5983 164 17 with with ADP fnp-5983 164 18 mn1 mn1 PROPN fnp-5983 164 19 - - PUNCT fnp-5983 164 20 bend2 bend2 NOUN fnp-5983 164 21 fusion fusion NOUN fnp-5983 164 22 in in ADP fnp-5983 164 23 spinal spinal ADJ fnp-5983 164 24 cord cord NOUN fnp-5983 164 25 and and CCONJ fnp-5983 164 26 literature literature PROPN fnp-5983 164 27 review review PROPN fnp-5983 164 28 . . PUNCT fnp-5983 165 1 clin clin PROPN fnp-5983 165 2 neuropathol neuropathol PROPN fnp-5983 165 3 . . PUNCT fnp-5983 166 1 2023;42:30–9 2023;42:30–9 NUM fnp-5983 166 2 . . PUNCT fnp-5983 167 1 https://doi.org/10.5414/np301497 https://doi.org/10.5414/np301497 PROPN fnp-5983 168 1 25 25 NUM fnp-5983 168 2 . . PUNCT fnp-5983 169 1 tauziède tauziède VERB fnp-5983 169 2 - - PUNCT fnp-5983 169 3 espariat espariat PROPN fnp-5983 169 4 a a PROPN fnp-5983 169 5 , , PUNCT fnp-5983 169 6 pagès pagès PROPN fnp-5983 169 7 m m PROPN fnp-5983 169 8 , , PUNCT fnp-5983 169 9 roux roux VERB fnp-5983 169 10 a a PRON fnp-5983 169 11 , , PUNCT fnp-5983 169 12 siegfried siegfrie VERB fnp-5983 169 13 a a DET fnp-5983 169 14 , , PUNCT fnp-5983 169 15 uro uro NOUN fnp-5983 169 16 - - PUNCT fnp-5983 169 17 coste coste NOUN fnp-5983 169 18 e e NOUN fnp-5983 169 19 , , PUNCT fnp-5983 169 20 nicaise nicaise PROPN fnp-5983 169 21 y y PROPN fnp-5983 169 22 , , PUNCT fnp-5983 169 23 et et PROPN fnp-5983 169 24 al al PROPN fnp-5983 169 25 . . PROPN fnp-5983 169 26 pediatric pediatric ADJ fnp-5983 169 27 methylation methylation NOUN fnp-5983 169 28 class class NOUN fnp-5983 169 29 hgnet hgnet NOUN fnp-5983 169 30 - - PUNCT fnp-5983 169 31 mn1 mn1 NOUN fnp-5983 169 32 : : PUNCT fnp-5983 169 33 unresolved unresolved ADJ fnp-5983 169 34 issues issue NOUN fnp-5983 169 35 with with ADP fnp-5983 169 36 terminology terminology NOUN fnp-5983 169 37 and and CCONJ fnp-5983 169 38 grading grading NOUN fnp-5983 169 39 . . PUNCT fnp-5983 170 1 acta acta PROPN fnp-5983 170 2 neuropathol neuropathol PROPN fnp-5983 170 3 commun commun PROPN fnp-5983 170 4 . . PUNCT fnp-5983 171 1 2019;7:176 2019;7:176 PROPN fnp-5983 171 2 . . PUNCT fnp-5983 172 1 https://doi.org/10.1186/s40478-019-0834-z https://doi.org/10.1186/s40478-019-0834-z PROPN fnp-5983 172 2 26 26 NUM fnp-5983 172 3 . . PUNCT fnp-5983 173 1 ujihara ujihara PROPN fnp-5983 173 2 m m PROPN fnp-5983 173 3 , , PUNCT fnp-5983 173 4 mishima mishima PROPN fnp-5983 173 5 k k PROPN fnp-5983 173 6 , , PUNCT fnp-5983 173 7 sasaki sasaki PROPN fnp-5983 173 8 a a X fnp-5983 173 9 , , PUNCT fnp-5983 173 10 adach adach ADP fnp-5983 173 11 j j PROPN fnp-5983 173 12 - - PUNCT fnp-5983 173 13 i i PROPN fnp-5983 173 14 , , PUNCT fnp-5983 173 15 shirahata shirahata PROPN fnp-5983 173 16 m m PROPN fnp-5983 173 17 , , PUNCT fnp-5983 173 18 suzuki suzuki PROPN fnp-5983 173 19 t t PROPN fnp-5983 173 20 , , PUNCT fnp-5983 173 21 et et PROPN fnp-5983 173 22 al al PROPN fnp-5983 173 23 . . PROPN fnp-5983 174 1 unique unique ADJ fnp-5983 174 2 pathological pathological ADJ fnp-5983 174 3 findings finding NOUN fnp-5983 174 4 of of ADP fnp-5983 174 5 astroblastoma astroblastoma NOUN fnp-5983 174 6 with with ADP fnp-5983 174 7 mn1 mn1 PROPN fnp-5983 174 8 alteration alteration NOUN fnp-5983 174 9 in in ADP fnp-5983 174 10 a a DET fnp-5983 174 11 patient patient NOUN fnp-5983 174 12 with with ADP fnp-5983 174 13 late late ADJ fnp-5983 174 14 recurrence recurrence NOUN fnp-5983 174 15 . . PUNCT fnp-5983 175 1 brain brain NOUN fnp-5983 175 2 tumor tumor NOUN fnp-5983 175 3 pathol pathol NOUN fnp-5983 175 4 . . PUNCT fnp-5983 176 1 2021;38:243–9 2021;38:243–9 NUM fnp-5983 176 2 . . PUNCT fnp-5983 177 1 https://doi.org/10.1007/s10014-021-00401-6 https://doi.org/10.1007/s10014-021-00401-6 PROPN fnp-5983 177 2 27 27 NUM fnp-5983 177 3 . . PUNCT fnp-5983 178 1 walker walker PROPN fnp-5983 178 2 en en PROPN fnp-5983 178 3 , , PUNCT fnp-5983 178 4 laws laws PROPN fnp-5983 178 5 mt mt PROPN fnp-5983 178 6 , , PUNCT fnp-5983 178 7 cozzi cozzi PROPN fnp-5983 178 8 f f PROPN fnp-5983 178 9 , , PUNCT fnp-5983 178 10 quezado quezado PROPN fnp-5983 178 11 m m PROPN fnp-5983 178 12 , , PUNCT fnp-5983 178 13 brown brown PROPN fnp-5983 178 14 da da PROPN fnp-5983 178 15 , , PUNCT fnp-5983 178 16 burton burton PROPN fnp-5983 178 17 ec ec PROPN fnp-5983 178 18 . . PUNCT fnp-5983 179 1 a a DET fnp-5983 179 2 case case NOUN fnp-5983 179 3 of of ADP fnp-5983 179 4 disseminated disseminate VERB fnp-5983 179 5 spinal spinal ADJ fnp-5983 179 6 astroblastoma astroblastoma NOUN fnp-5983 179 7 harboring harbor VERB fnp-5983 179 8 a a DET fnp-5983 179 9 mamld1::bend2 mamld1::bend2 NOUN fnp-5983 179 10 fusion fusion NOUN fnp-5983 179 11 . . PUNCT fnp-5983 180 1 neuropathology neuropathology NOUN fnp-5983 180 2 . . PUNCT fnp-5983 181 1 2024;44:278 2024;44:278 NOUN fnp-5983 181 2 - - PUNCT fnp-5983 181 3 84 84 NUM fnp-5983 181 4 . . PUNCT fnp-5983 182 1 https://doi.org/10.1111/neup.12960 https://doi.org/10.1111/neup.12960 NUM fnp-5983 182 2 28 28 NUM fnp-5983 182 3 . . PUNCT fnp-5983 183 1 wood wood PROPN fnp-5983 183 2 md md PROPN fnp-5983 183 3 , , PUNCT fnp-5983 183 4 tihan tihan PROPN fnp-5983 183 5 t t PROPN fnp-5983 183 6 , , PUNCT fnp-5983 183 7 perry perry PROPN fnp-5983 183 8 a a PRON fnp-5983 183 9 , , PUNCT fnp-5983 183 10 chacko chacko NOUN fnp-5983 183 11 g g NOUN fnp-5983 183 12 , , PUNCT fnp-5983 183 13 turner turner PROPN fnp-5983 183 14 c c PROPN fnp-5983 183 15 , , PUNCT fnp-5983 183 16 pu pu PROPN fnp-5983 183 17 c c PROPN fnp-5983 183 18 , , PUNCT fnp-5983 183 19 et et PROPN fnp-5983 183 20 al al PROPN fnp-5983 183 21 . . PUNCT fnp-5983 184 1 multimodal multimodal ADJ fnp-5983 184 2 molecular molecular ADJ fnp-5983 184 3 analysis analysis NOUN fnp-5983 184 4 of of ADP fnp-5983 184 5 astroblastoma astroblastoma NOUN fnp-5983 184 6 enables enable VERB fnp-5983 184 7 reclassification reclassification NOUN fnp-5983 184 8 of of ADP fnp-5983 184 9 most most ADJ fnp-5983 184 10 cases case NOUN fnp-5983 184 11 into into ADP fnp-5983 184 12 more more ADV fnp-5983 184 13 specific specific ADJ fnp-5983 184 14 molecular molecular ADJ fnp-5983 184 15 entities entity NOUN fnp-5983 184 16 . . PUNCT fnp-5983 185 1 brain brain NOUN fnp-5983 185 2 pathol pathol NOUN fnp-5983 185 3 . . PUNCT fnp-5983 186 1 2018;28:192–202 2018;28:192–202 NOUN fnp-5983 186 2 . . PUNCT fnp-5983 187 1 https://doi.org/10.1111/bpa.12561 https://doi.org/10.1111/bpa.12561 PROPN fnp-5983 187 2 29 29 NUM fnp-5983 187 3 . . PUNCT fnp-5983 188 1 liu liu PROPN fnp-5983 188 2 j j PROPN fnp-5983 188 3 , , PUNCT fnp-5983 188 4 sun sun PROPN fnp-5983 188 5 d d PROPN fnp-5983 188 6 , , PUNCT fnp-5983 188 7 lin lin PROPN fnp-5983 188 8 f f PROPN fnp-5983 188 9 , , PUNCT fnp-5983 188 10 li li PROPN fnp-5983 188 11 y y PROPN fnp-5983 188 12 , , PUNCT fnp-5983 188 13 wu wu PROPN fnp-5983 188 14 t t PROPN fnp-5983 188 15 , , PUNCT fnp-5983 188 16 liu liu PROPN fnp-5983 188 17 x. x. PROPN fnp-5983 189 1 an an DET fnp-5983 189 2 ewsr1 ewsr1 ADJ fnp-5983 189 3 - - PUNCT fnp-5983 189 4 ezhip ezhip NOUN fnp-5983 189 5 fusion fusion NOUN fnp-5983 189 6 in in ADP fnp-5983 189 7 a a DET fnp-5983 189 8 cerebral cerebral ADJ fnp-5983 189 9 hemisphere hemisphere ADJ fnp-5983 189 10 astroblastoma astroblastoma NOUN fnp-5983 189 11 . . PUNCT fnp-5983 190 1 neuropathology neuropathology NOUN fnp-5983 190 2 . . PUNCT fnp-5983 191 1 2023;43:340–4 2023;43:340–4 NUM fnp-5983 191 2 . . PUNCT fnp-5983 192 1 https://doi.org/10.1111/neup.12893 https://doi.org/10.1111/neup.12893 ADJ fnp-5983 192 2 30 30 NUM fnp-5983 192 3 . . PUNCT fnp-5983 193 1 antonescu antonescu PROPN fnp-5983 193 2 cr cr PROPN fnp-5983 193 3 , , PUNCT fnp-5983 193 4 dickson dickson PROPN fnp-5983 193 5 bc bc PROPN fnp-5983 193 6 , , PUNCT fnp-5983 193 7 zhang zhang PROPN fnp-5983 193 8 l l PROPN fnp-5983 193 9 , , PUNCT fnp-5983 193 10 sung sing VERB fnp-5983 193 11 y y PROPN fnp-5983 193 12 - - PUNCT fnp-5983 193 13 s s PROPN fnp-5983 193 14 , , PUNCT fnp-5983 193 15 fletcher fletcher PROPN fnp-5983 193 16 cd cd PROPN fnp-5983 193 17 . . PROPN fnp-5983 194 1 unclassified unclassified ADJ fnp-5983 194 2 low low ADJ fnp-5983 194 3 grade grade NOUN fnp-5983 194 4 spindle spindle NOUN fnp-5983 194 5 cell cell NOUN fnp-5983 194 6 sarcoma sarcoma NOUN fnp-5983 194 7 with with ADP fnp-5983 194 8 storiform storiform NOUN fnp-5983 194 9 pattern pattern NOUN fnp-5983 194 10 characterized characterize VERB fnp-5983 194 11 by by ADP fnp-5983 194 12 recurrent recurrent ADJ fnp-5983 194 13 novel novel NOUN fnp-5983 194 14 ewsr1 ewsr1 PROPN fnp-5983 194 15 / / SYM fnp-5983 194 16 fus fus ADJ fnp-5983 194 17 - - PUNCT fnp-5983 194 18 nacc1 nacc1 NOUN fnp-5983 194 19 fusions fusion NOUN fnp-5983 194 20 . . PUNCT fnp-5983 195 1 mod mod PROPN fnp-5983 195 2 pathol pathol PROPN fnp-5983 195 3 . . PUNCT fnp-5983 196 1 2021;34:1541–6 2021;34:1541–6 X fnp-5983 196 2 . . PUNCT fnp-5983 197 1 https://doi.org/10.1038/s41379-021-00805-x https://doi.org/10.1038/s41379-021-00805-x PROPN fnp-5983 197 2 31 31 NUM fnp-5983 197 3 . . PUNCT fnp-5983 198 1 rooper rooper PROPN fnp-5983 198 2 lm lm PROPN fnp-5983 198 3 , , PUNCT fnp-5983 198 4 gagan gagan PROPN fnp-5983 198 5 j j PROPN fnp-5983 198 6 , , PUNCT fnp-5983 198 7 bishop bishop PROPN fnp-5983 198 8 ja ja PROPN fnp-5983 198 9 . . PUNCT fnp-5983 199 1 a a DET fnp-5983 199 2 low low ADJ fnp-5983 199 3 grade grade NOUN fnp-5983 199 4 nasopharyngeal nasopharyngeal ADJ fnp-5983 199 5 sarcoma sarcoma NOUN fnp-5983 199 6 with with ADP fnp-5983 199 7 fus::nacc1 fus::nacc1 ADJ fnp-5983 199 8 fusion fusion NOUN fnp-5983 199 9 and and CCONJ fnp-5983 199 10 immunohistochemical immunohistochemical ADJ fnp-5983 199 11 evidence evidence NOUN fnp-5983 199 12 of of ADP fnp-5983 199 13 epithelial epithelial ADJ fnp-5983 199 14 differentiation differentiation NOUN fnp-5983 199 15 : : PUNCT fnp-5983 199 16 expanding expand VERB fnp-5983 199 17 the the DET fnp-5983 199 18 clinicopathologic clinicopathologic ADJ fnp-5983 199 19 spectrum spectrum NOUN fnp-5983 199 20 of of ADP fnp-5983 199 21 an an DET fnp-5983 199 22 emerging emerge VERB fnp-5983 199 23 entity entity NOUN fnp-5983 199 24 . . PUNCT fnp-5983 200 1 head head NOUN fnp-5983 200 2 neck neck NOUN fnp-5983 200 3 pathol pathol NOUN fnp-5983 200 4 . . PUNCT fnp-5983 201 1 2023;17:253–8 2023;17:253–8 X fnp-5983 201 2 . . PUNCT fnp-5983 202 1 https://doi.org/10.1007/s12105-022-01488-9 https://doi.org/10.1007/s12105-022-01488-9 NOUN fnp-5983 202 2 32 32 NUM fnp-5983 202 3 . . PUNCT fnp-5983 203 1 schwartz schwartz PROPN fnp-5983 203 2 jc jc PROPN fnp-5983 203 3 , , PUNCT fnp-5983 203 4 cech cech NOUN fnp-5983 203 5 tr tr VERB fnp-5983 203 6 , , PUNCT fnp-5983 203 7 parker parker PROPN fnp-5983 203 8 rr rr PROPN fnp-5983 203 9 . . PUNCT fnp-5983 204 1 biochemical biochemical ADJ fnp-5983 204 2 properties property NOUN fnp-5983 204 3 and and CCONJ fnp-5983 204 4 biological biological ADJ fnp-5983 204 5 functions function NOUN fnp-5983 204 6 of of ADP fnp-5983 204 7 fet fet PROPN fnp-5983 204 8 proteins protein NOUN fnp-5983 204 9 . . PUNCT fnp-5983 205 1 annu annu PROPN fnp-5983 205 2 rev rev VERB fnp-5983 205 3 biochem biochem PROPN fnp-5983 205 4 . . PUNCT fnp-5983 206 1 2015;84:355–79 2015;84:355–79 ADV fnp-5983 206 2 . . PUNCT fnp-5983 207 1 https://doi.org/10.1146/annurev-biochem-060614-034325 https://doi.org/10.1146/annurev-biochem-060614-034325 PROPN fnp-5983 207 2 33 33 NUM fnp-5983 207 3 . . PUNCT fnp-5983 208 1 dai dai PROPN fnp-5983 208 2 q q PROPN fnp-5983 208 3 , , PUNCT fnp-5983 208 4 ren ren PROPN fnp-5983 208 5 a a PRON fnp-5983 208 6 , , PUNCT fnp-5983 208 7 westholm westholm PROPN fnp-5983 208 8 jo jo PROPN fnp-5983 208 9 , , PUNCT fnp-5983 208 10 serganov serganov PROPN fnp-5983 208 11 aa aa PROPN fnp-5983 208 12 , , PUNCT fnp-5983 208 13 patel patel PROPN fnp-5983 208 14 dj dj PROPN fnp-5983 208 15 , , PUNCT fnp-5983 208 16 lai lai PROPN fnp-5983 208 17 ec ec PROPN fnp-5983 208 18 . . PUNCT fnp-5983 209 1 the the DET fnp-5983 209 2 ben ben PROPN fnp-5983 209 3 domain domain PROPN fnp-5983 209 4 is be AUX fnp-5983 209 5 a a DET fnp-5983 209 6 novel novel ADJ fnp-5983 209 7 sequence sequence NOUN fnp-5983 209 8 - - PUNCT fnp-5983 209 9 specific specific ADJ fnp-5983 209 10 dna dna NOUN fnp-5983 209 11 - - PUNCT fnp-5983 209 12 binding bind VERB fnp-5983 209 13 domain domain NOUN fnp-5983 209 14 conserved conserve VERB fnp-5983 209 15 in in ADP fnp-5983 209 16 neural neural ADJ fnp-5983 209 17 transcriptional transcriptional ADJ fnp-5983 209 18 repressors repressor NOUN fnp-5983 209 19 . . PUNCT fnp-5983 210 1 genes gene NOUN fnp-5983 210 2 dev dev PROPN fnp-5983 210 3 . . PUNCT fnp-5983 211 1 2013;27:602–14 2013;27:602–14 X fnp-5983 211 2 . . PUNCT fnp-5983 212 1 https://doi.org/10.1101/gad.213314.113 https://doi.org/10.1101/gad.213314.113 PROPN fnp-5983 212 2 34 34 NUM fnp-5983 212 3 . . PUNCT fnp-5983 213 1 lehman lehman PROPN fnp-5983 213 2 nl nl PROPN fnp-5983 213 3 . . PUNCT fnp-5983 214 1 early early ADJ fnp-5983 214 2 ependymal ependymal ADJ fnp-5983 214 3 tumor tumor NOUN fnp-5983 214 4 with with ADP fnp-5983 214 5 mn1 mn1 PROPN fnp-5983 214 6 - - PUNCT fnp-5983 214 7 bend2 bend2 NOUN fnp-5983 214 8 fusion fusion NOUN fnp-5983 214 9 : : PUNCT fnp-5983 214 10 a a DET fnp-5983 214 11 mostly mostly ADV fnp-5983 214 12 cerebral cerebral ADJ fnp-5983 214 13 tumor tumor NOUN fnp-5983 214 14 of of ADP fnp-5983 214 15 female female ADJ fnp-5983 214 16 children child NOUN fnp-5983 214 17 with with ADP fnp-5983 214 18 a a DET fnp-5983 214 19 good good ADJ fnp-5983 214 20 prognosis prognosis NOUN fnp-5983 214 21 that that PRON fnp-5983 214 22 is be AUX fnp-5983 214 23 distinct distinct ADJ fnp-5983 214 24 from from ADP fnp-5983 214 25 classical classical ADJ fnp-5983 214 26 astroblastoma astroblastoma NOUN fnp-5983 214 27 . . PUNCT fnp-5983 215 1 j j PROPN fnp-5983 215 2 neurooncol neurooncol PROPN fnp-5983 215 3 . . PUNCT fnp-5983 216 1 2023;161:425–39 2023;161:425–39 NUM fnp-5983 216 2 . . PUNCT fnp-5983 217 1 https://doi.org/10.1007/s11060-022-04222-1 https://doi.org/10.1007/s11060-022-04222-1 PROPN fnp-5983 217 2 copyright copyright NOUN fnp-5983 217 3 : : PUNCT fnp-5983 217 4 © © PROPN fnp-5983 217 5 2024 2024 NUM fnp-5983 217 6 the the DET fnp-5983 217 7 author(s author(s NOUN fnp-5983 217 8 ) ) PUNCT fnp-5983 217 9 . . PUNCT fnp-5983 218 1 this this PRON fnp-5983 218 2 is be AUX fnp-5983 218 3 an an DET fnp-5983 218 4 open open ADJ fnp-5983 218 5 access access NOUN fnp-5983 218 6 article article NOUN fnp-5983 218 7 distributed distribute VERB fnp-5983 218 8 under under ADP fnp-5983 218 9 the the DET fnp-5983 218 10 terms term NOUN fnp-5983 218 11 of of ADP fnp-5983 218 12 the the DET fnp-5983 218 13 creative creative ADJ fnp-5983 218 14 commons common NOUN fnp-5983 218 15 attribution attribution NOUN fnp-5983 218 16 4.0 4.0 NUM fnp-5983 218 17 international international ADJ fnp-5983 218 18 license license NOUN fnp-5983 218 19 ( ( PUNCT fnp-5983 218 20 https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/ PROPN fnp-5983 218 21 ) ) PUNCT fnp-5983 218 22 , , PUNCT fnp-5983 218 23 which which PRON fnp-5983 218 24 permits permit VERB fnp-5983 218 25 unrestricted unrestricted ADJ fnp-5983 218 26 use use NOUN fnp-5983 218 27 , , PUNCT fnp-5983 218 28 distribution distribution NOUN fnp-5983 218 29 , , PUNCT fnp-5983 218 30 and and CCONJ fnp-5983 218 31 reproduction reproduction NOUN fnp-5983 218 32 in in ADP fnp-5983 218 33 any any DET fnp-5983 218 34 medium medium NOUN fnp-5983 218 35 , , PUNCT fnp-5983 218 36 provided provide VERB fnp-5983 218 37 the the DET fnp-5983 218 38 original original ADJ fnp-5983 218 39 author author NOUN fnp-5983 218 40 and and CCONJ fnp-5983 218 41 source source NOUN fnp-5983 218 42 are be AUX fnp-5983 218 43 credited credit VERB fnp-5983 218 44 , , PUNCT fnp-5983 218 45 a a DET fnp-5983 218 46 link link NOUN fnp-5983 218 47 to to ADP fnp-5983 218 48 the the DET fnp-5983 218 49 creative creative ADJ fnp-5983 218 50 commons common NOUN fnp-5983 218 51 license license NOUN fnp-5983 218 52 is be AUX fnp-5983 218 53 provided provide VERB fnp-5983 218 54 , , PUNCT fnp-5983 218 55 and and CCONJ fnp-5983 218 56 any any DET fnp-5983 218 57 changes change NOUN fnp-5983 218 58 are be AUX fnp-5983 218 59 indicated indicate VERB fnp-5983 218 60 . . PUNCT fnp-5983 219 1 the the DET fnp-5983 219 2 creative creative ADJ fnp-5983 219 3 commons common NOUN fnp-5983 219 4 public public ADJ fnp-5983 219 5 domain domain NOUN fnp-5983 219 6 dedication dedication NOUN fnp-5983 219 7 waiver waiver NOUN fnp-5983 219 8 ( ( PUNCT fnp-5983 219 9 https://creativecommons.org/publicdomain/zero/1.0/ https://creativecommons.org/publicdomain/zero/1.0/ PROPN fnp-5983 219 10 ) ) PUNCT fnp-5983 219 11 applies apply VERB fnp-5983 219 12 to to ADP fnp-5983 219 13 the the DET fnp-5983 219 14 data datum NOUN fnp-5983 219 15 made make VERB fnp-5983 219 16 available available ADJ fnp-5983 219 17 in in ADP fnp-5983 219 18 this this DET fnp-5983 219 19 article article NOUN fnp-5983 219 20 , , PUNCT fnp-5983 219 21 unless unless SCONJ fnp-5983 219 22 otherwise otherwise ADV fnp-5983 219 23 stated state VERB fnp-5983 219 24 . . PUNCT