id	sid	tid	token	lemma	pos
fnp-6108	1	1	northern	northern	ADJ
fnp-6108	1	2	lights	light	NOUN
fnp-6108	1	3	neuroscience	neuroscience	NOUN
fnp-6108	1	4	symposium	symposium	NOUN
fnp-6108	1	5	2024	2024	NUM
fnp-6108	1	6	feel	feel	VERB
fnp-6108	1	7	free	free	ADJ
fnp-6108	1	8	to	to	PART
fnp-6108	1	9	add	add	VERB
fnp-6108	1	10	comments	comment	NOUN
fnp-6108	1	11	by	by	ADP
fnp-6108	1	12	clicking	click	VERB
fnp-6108	1	13	these	these	DET
fnp-6108	1	14	icons	icon	NOUN
fnp-6108	1	15	on	on	ADP
fnp-6108	1	16	the	the	DET
fnp-6108	1	17	sidebar	sidebar	NOUN
fnp-6108	1	18	free	free	ADJ
fnp-6108	1	19	neuropathology	neuropathology	NOUN
fnp-6108	1	20	5:30	5:30	NUM
fnp-6108	1	21	(	(	PUNCT
fnp-6108	1	22	2024	2024	NUM
fnp-6108	1	23	)	)	PUNCT
fnp-6108	1	24	meeting	meeting	NOUN
fnp-6108	1	25	abstracts	abstract	VERB
fnp-6108	1	26	northern	northern	ADJ
fnp-6108	1	27	lights	light	NOUN
fnp-6108	1	28	neuroscience	neuroscience	NOUN
fnp-6108	1	29	symposium	symposium	NOUN
fnp-6108	1	30	2024	2024	NUM
fnp-6108	1	31	expanding	expand	VERB
fnp-6108	1	32	spectrum	spectrum	NOUN
fnp-6108	1	33	of	of	ADP
fnp-6108	1	34	common	common	ADJ
fnp-6108	1	35	dementia	dementia	NOUN
fnp-6108	1	36	disorders	disorder	NOUN
fnp-6108	1	37	meeting	meet	VERB
fnp-6108	1	38	abstracts	abstract	NOUN
fnp-6108	1	39	september	september	PROPN
fnp-6108	1	40	26–27	26–27	PROPN
fnp-6108	1	41	,	,	PUNCT
fnp-6108	1	42	2024	2024	NUM
fnp-6108	1	43	  	  	SPACE
fnp-6108	1	44	the	the	DET
fnp-6108	1	45	northern	northern	ADJ
fnp-6108	1	46	lights	light	NOUN
fnp-6108	1	47	neuroscience	neuroscience	NOUN
fnp-6108	1	48	symposium	symposium	NOUN
fnp-6108	1	49	2024	2024	NUM
fnp-6108	1	50	“	"	PUNCT
fnp-6108	1	51	expanding	expand	VERB
fnp-6108	1	52	spectrum	spectrum	NOUN
fnp-6108	1	53	of	of	ADP
fnp-6108	1	54	common	common	ADJ
fnp-6108	1	55	dementia	dementia	NOUN
fnp-6108	1	56	disorders	disorder	NOUN
fnp-6108	1	57	”	"	PUNCT
fnp-6108	1	58	was	be	AUX
fnp-6108	1	59	held	hold	VERB
fnp-6108	1	60	in	in	ADP
fnp-6108	1	61	hanasaari	hanasaari	ADJ
fnp-6108	1	62	,	,	PUNCT
fnp-6108	1	63	helsinki	helsinki	PROPN
fnp-6108	1	64	(	(	PUNCT
fnp-6108	1	65	espoo	espoo	PROPN
fnp-6108	1	66	)	)	PUNCT
fnp-6108	1	67	,	,	PUNCT
fnp-6108	1	68	finland	finland	PROPN
fnp-6108	1	69	on	on	ADP
fnp-6108	1	70	september	september	PROPN
fnp-6108	1	71	26–27	26–27	PROPN
fnp-6108	1	72	,	,	PUNCT
fnp-6108	1	73	2024	2024	NUM
fnp-6108	1	74	.	.	PUNCT
fnp-6108	2	1	the	the	DET
fnp-6108	2	2	meeting	meeting	NOUN
fnp-6108	2	3	was	be	AUX
fnp-6108	2	4	jointly	jointly	ADV
fnp-6108	2	5	organised	organise	VERB
fnp-6108	2	6	by	by	ADP
fnp-6108	2	7	the	the	DET
fnp-6108	2	8	scandinavian	scandinavian	ADJ
fnp-6108	2	9	neuropathological	neuropathological	ADJ
fnp-6108	2	10	society	society	NOUN
fnp-6108	2	11	(	(	PUNCT
fnp-6108	2	12	chair	chair	PROPN
fnp-6108	2	13	olivera	olivera	PROPN
fnp-6108	2	14	casar	casar	PROPN
fnp-6108	2	15	-	-	NOUN
fnp-6108	2	16	borota	borota	NOUN
fnp-6108	2	17	)	)	PUNCT
fnp-6108	2	18	and	and	CCONJ
fnp-6108	2	19	university	university	PROPN
fnp-6108	2	20	of	of	ADP
fnp-6108	2	21	helsinki	helsinki	PROPN
fnp-6108	2	22	.	.	PUNCT
fnp-6108	3	1	drs	drs	PROPN
fnp-6108	3	2	.	.	PUNCT
fnp-6108	4	1	liisa	liisa	PROPN
fnp-6108	4	2	myllykangas	myllykangas	PROPN
fnp-6108	4	3	(	(	PUNCT
fnp-6108	4	4	chair	chair	NOUN
fnp-6108	4	5	)	)	PUNCT
fnp-6108	4	6	,	,	PUNCT
fnp-6108	4	7	olli	olli	PROPN
fnp-6108	4	8	tynninen	tynninen	PROPN
fnp-6108	4	9	,	,	PUNCT
fnp-6108	4	10	maria	maria	PROPN
fnp-6108	4	11	gardberg	gardberg	PROPN
fnp-6108	4	12	and	and	CCONJ
fnp-6108	4	13	tuomas	tuomas	PROPN
fnp-6108	4	14	rauramaa	rauramaa	NOUN
fnp-6108	4	15	made	make	VERB
fnp-6108	4	16	up	up	ADP
fnp-6108	4	17	the	the	DET
fnp-6108	4	18	organising	organise	VERB
fnp-6108	4	19	committee	committee	NOUN
fnp-6108	4	20	.	.	PUNCT
fnp-6108	5	1	the	the	DET
fnp-6108	5	2	event	event	NOUN
fnp-6108	5	3	brought	bring	VERB
fnp-6108	5	4	together	together	ADV
fnp-6108	5	5	neuropathologists	neuropathologist	NOUN
fnp-6108	5	6	,	,	PUNCT
fnp-6108	5	7	clinicians	clinician	NOUN
fnp-6108	5	8	and	and	CCONJ
fnp-6108	5	9	neuroscientists	neuroscientist	NOUN
fnp-6108	5	10	from	from	ADP
fnp-6108	5	11	nine	nine	NUM
fnp-6108	5	12	different	different	ADJ
fnp-6108	5	13	counties	county	NOUN
fnp-6108	5	14	.	.	PUNCT
fnp-6108	6	1	in	in	ADP
fnp-6108	6	2	total	total	ADJ
fnp-6108	6	3	,	,	PUNCT
fnp-6108	6	4	91	91	NUM
fnp-6108	6	5	people	people	NOUN
fnp-6108	6	6	had	have	AUX
fnp-6108	6	7	registered	register	VERB
fnp-6108	6	8	for	for	ADP
fnp-6108	6	9	the	the	DET
fnp-6108	6	10	meeting	meeting	NOUN
fnp-6108	6	11	,	,	PUNCT
fnp-6108	6	12	and	and	CCONJ
fnp-6108	6	13	there	there	PRON
fnp-6108	6	14	were	be	VERB
fnp-6108	6	15	29	29	NUM
fnp-6108	6	16	abstracts	abstract	NOUN
fnp-6108	6	17	.	.	PUNCT
fnp-6108	7	1	the	the	DET
fnp-6108	7	2	keynote	keynote	NOUN
fnp-6108	7	3	lectures	lecture	VERB
fnp-6108	7	4	on	on	ADP
fnp-6108	7	5	neuropathological	neuropathological	ADJ
fnp-6108	7	6	and	and	CCONJ
fnp-6108	7	7	clinical	clinical	ADJ
fnp-6108	7	8	aspects	aspect	NOUN
fnp-6108	7	9	of	of	ADP
fnp-6108	7	10	new	new	ADJ
fnp-6108	7	11	dementia	dementia	NOUN
fnp-6108	7	12	entities	entity	NOUN
fnp-6108	7	13	such	such	ADJ
fnp-6108	7	14	as	as	ADP
fnp-6108	7	15	late	late	ADJ
fnp-6108	7	16	and	and	CCONJ
fnp-6108	7	17	part	part	NOUN
fnp-6108	7	18	as	as	ADV
fnp-6108	7	19	well	well	ADV
fnp-6108	7	20	as	as	ADP
fnp-6108	7	21	subtypes	subtype	NOUN
fnp-6108	7	22	of	of	ADP
fnp-6108	7	23	ad	ad	NOUN
fnp-6108	7	24	and	and	CCONJ
fnp-6108	7	25	lbd	lbd	PROPN
fnp-6108	7	26	,	,	PUNCT
fnp-6108	7	27	vascular	vascular	ADJ
fnp-6108	7	28	and	and	CCONJ
fnp-6108	7	29	mixed	mixed	ADJ
fnp-6108	7	30	patologies	patologie	NOUN
fnp-6108	7	31	,	,	PUNCT
fnp-6108	7	32	were	be	AUX
fnp-6108	7	33	given	give	VERB
fnp-6108	7	34	by	by	ADP
fnp-6108	7	35	irina	irina	PROPN
fnp-6108	7	36	alafuzoff	alafuzoff	PROPN
fnp-6108	7	37	,	,	PUNCT
fnp-6108	7	38	peter	peter	PROPN
fnp-6108	7	39	nelson	nelson	PROPN
fnp-6108	7	40	,	,	PUNCT
fnp-6108	7	41	david	david	PROPN
fnp-6108	7	42	wolk	wolk	PROPN
fnp-6108	7	43	,	,	PUNCT
fnp-6108	7	44	gabor	gabor	PROPN
fnp-6108	7	45	kovacs	kovacs	PROPN
fnp-6108	7	46	,	,	PUNCT
fnp-6108	7	47	melissa	melissa	PROPN
fnp-6108	7	48	murray	murray	PROPN
fnp-6108	7	49	,	,	PUNCT
fnp-6108	7	50	jacob	jacob	PROPN
fnp-6108	7	51	vogel	vogel	PROPN
fnp-6108	7	52	,	,	PUNCT
fnp-6108	7	53	liisa	liisa	NOUN
fnp-6108	7	54	myllykangas	myllykanga	NOUN
fnp-6108	7	55	,	,	PUNCT
fnp-6108	7	56	per	per	ADP
fnp-6108	7	57	borghammer	borghammer	NOUN
fnp-6108	7	58	,	,	PUNCT
fnp-6108	7	59	johannes	johanne	NOUN
fnp-6108	7	60	attems	attem	NOUN
fnp-6108	7	61	and	and	CCONJ
fnp-6108	7	62	masafumi	masafumi	ADJ
fnp-6108	7	63	ihara	ihara	NOUN
fnp-6108	7	64	.	.	PUNCT
fnp-6108	8	1	the	the	DET
fnp-6108	8	2	patrick	patrick	PROPN
fnp-6108	8	3	sourander	sourander	PROPN
fnp-6108	8	4	lecture	lecture	VERB
fnp-6108	8	5	“	"	PUNCT
fnp-6108	8	6	investigating	investigate	VERB
fnp-6108	8	7	choroid	choroid	NOUN
fnp-6108	8	8	plexus	plexus	NOUN
fnp-6108	8	9	and	and	CCONJ
fnp-6108	8	10	cerebrospinal	cerebrospinal	ADJ
fnp-6108	8	11	fluid	fluid	ADJ
fnp-6108	8	12	roles	role	NOUN
fnp-6108	8	13	and	and	CCONJ
fnp-6108	8	14	functions	function	NOUN
fnp-6108	8	15	in	in	ADP
fnp-6108	8	16	neurologic	neurologic	ADJ
fnp-6108	8	17	disease	disease	NOUN
fnp-6108	8	18	“	"	PUNCT
fnp-6108	8	19	was	be	AUX
fnp-6108	8	20	presented	present	VERB
fnp-6108	8	21	by	by	ADP
fnp-6108	8	22	maria	maria	PROPN
fnp-6108	8	23	lehtinen	lehtinen	PROPN
fnp-6108	8	24	from	from	ADP
fnp-6108	8	25	harvard	harvard	PROPN
fnp-6108	8	26	medical	medical	PROPN
fnp-6108	8	27	school	school	PROPN
fnp-6108	8	28	.	.	PUNCT
fnp-6108	9	1	seven	seven	NUM
fnp-6108	9	2	additional	additional	ADJ
fnp-6108	9	3	oral	oral	ADJ
fnp-6108	9	4	presentations	presentation	NOUN
fnp-6108	9	5	(	(	PUNCT
fnp-6108	9	6	selected	select	VERB
fnp-6108	9	7	from	from	ADP
fnp-6108	9	8	submitted	submit	VERB
fnp-6108	9	9	abstracts	abstract	NOUN
fnp-6108	9	10	)	)	PUNCT
fnp-6108	9	11	were	be	AUX
fnp-6108	9	12	also	also	ADV
fnp-6108	9	13	given	give	VERB
fnp-6108	9	14	.	.	PUNCT
fnp-6108	10	1	the	the	DET
fnp-6108	10	2	participants	participant	NOUN
fnp-6108	10	3	were	be	AUX
fnp-6108	10	4	highly	highly	ADV
fnp-6108	10	5	appreciative	appreciative	ADJ
fnp-6108	10	6	of	of	ADP
fnp-6108	10	7	the	the	DET
fnp-6108	10	8	meeting	meeting	NOUN
fnp-6108	10	9	’s	’s	PART
fnp-6108	10	10	top	top	ADJ
fnp-6108	10	11	level	level	NOUN
fnp-6108	10	12	scientific	scientific	ADJ
fnp-6108	10	13	content	content	NOUN
fnp-6108	10	14	and	and	CCONJ
fnp-6108	10	15	of	of	ADP
fnp-6108	10	16	the	the	DET
fnp-6108	10	17	networking	network	VERB
fnp-6108	10	18	event	event	NOUN
fnp-6108	10	19	,	,	PUNCT
fnp-6108	10	20	which	which	PRON
fnp-6108	10	21	included	include	VERB
fnp-6108	10	22	a	a	DET
fnp-6108	10	23	finnish	finnish	ADJ
fnp-6108	10	24	sauna	sauna	NOUN
fnp-6108	10	25	,	,	PUNCT
fnp-6108	10	26	a	a	DET
fnp-6108	10	27	cruise	cruise	NOUN
fnp-6108	10	28	in	in	ADP
fnp-6108	10	29	the	the	DET
fnp-6108	10	30	helsinki	helsinki	PROPN
fnp-6108	10	31	archipelago	archipelago	PROPN
fnp-6108	10	32	and	and	CCONJ
fnp-6108	10	33	a	a	DET
fnp-6108	10	34	dinner	dinner	NOUN
fnp-6108	10	35	in	in	ADP
fnp-6108	10	36	the	the	DET
fnp-6108	10	37	center	center	NOUN
fnp-6108	10	38	of	of	ADP
fnp-6108	10	39	helsinki	helsinki	PROPN
fnp-6108	10	40	.	.	PUNCT
fnp-6108	10	41	  	  	SPACE
fnp-6108	11	1	https://doi.org/10.17879/freeneuropathology-2024-6108	https://doi.org/10.17879/freeneuropathology-2024-6108	PROPN
fnp-6108	11	2	keywords	keyword	NOUN
fnp-6108	11	3	:	:	PUNCT
fnp-6108	11	4	scandinavian	scandinavian	ADJ
fnp-6108	11	5	neuropathological	neuropathological	ADJ
fnp-6108	11	6	society	society	NOUN
fnp-6108	11	7	,	,	PUNCT
fnp-6108	11	8	meeting	meet	VERB
fnp-6108	11	9	abstracts	abstract	NOUN
fnp-6108	11	10	,	,	PUNCT
fnp-6108	11	11	northern	northern	ADJ
fnp-6108	11	12	lights	light	NOUN
fnp-6108	11	13	neuroscience	neuroscience	NOUN
fnp-6108	11	14	symposium	symposium	NOUN
fnp-6108	11	15	2024	2024	NUM
fnp-6108	11	16	meeting	meeting	NOUN
fnp-6108	11	17	abstracts	abstract	VERB
fnp-6108	11	18	irina	irina	PROPN
fnp-6108	11	19	alafuzoff	alafuzoff	PROPN
fnp-6108	11	20	expanding	expand	VERB
fnp-6108	11	21	spectrum	spectrum	NOUN
fnp-6108	11	22	of	of	ADP
fnp-6108	11	23	dementia	dementia	NOUN
fnp-6108	11	24	disorders	disorder	NOUN
fnp-6108	11	25	remarh	remarh	NOUN
fnp-6108	11	26	bsoul	bsoul	NOUN
fnp-6108	11	27	et	et	PROPN
fnp-6108	11	28	al	al	PROPN
fnp-6108	11	29	rt	rt	PROPN
fnp-6108	11	30	-	-	PUNCT
fnp-6108	11	31	quic	quic	PROPN
fnp-6108	11	32	with	with	ADP
fnp-6108	11	33	universal	universal	ADJ
fnp-6108	11	34	control	control	NOUN
fnp-6108	11	35	fluid	fluid	NOUN
fnp-6108	11	36	:	:	PUNCT
fnp-6108	11	37	standardized	standardized	ADJ
fnp-6108	11	38	detection	detection	NOUN
fnp-6108	11	39	of	of	ADP
fnp-6108	11	40	alpha	alpha	NOUN
fnp-6108	11	41	-	-	PUNCT
fnp-6108	11	42	synucleinopathies	synucleinopathie	NOUN
fnp-6108	11	43	johannes	johanne	NOUN
fnp-6108	11	44	attems	attem	VERB
fnp-6108	11	45	mixed	mixed	ADJ
fnp-6108	11	46	pathologies	pathology	NOUN
fnp-6108	11	47	of	of	ADP
fnp-6108	11	48	the	the	DET
fnp-6108	11	49	ageing	age	VERB
fnp-6108	11	50	brain	brain	NOUN
fnp-6108	11	51	emmilotta	emmilotta	PROPN
fnp-6108	11	52	backman	backman	PROPN
fnp-6108	11	53	et	et	PROPN
fnp-6108	11	54	al	al	PROPN
fnp-6108	11	55	nigral	nigral	PROPN
fnp-6108	11	56	neuroinflammation	neuroinflammation	PROPN
fnp-6108	11	57	and	and	CCONJ
fnp-6108	11	58	dopaminergic	dopaminergic	ADJ
fnp-6108	11	59	neurons	neuron	NOUN
fnp-6108	11	60	in	in	ADP
fnp-6108	11	61	pd	pd	PROPN
fnp-6108	11	62	,	,	PUNCT
fnp-6108	11	63	msa	msa	PROPN
fnp-6108	11	64	and	and	CCONJ
fnp-6108	11	65	psp	psp	PROPN
fnp-6108	11	66	:	:	PUNCT
fnp-6108	11	67	a	a	DET
fnp-6108	11	68	comparative	comparative	ADJ
fnp-6108	11	69	clinicopathological	clinicopathological	ADJ
fnp-6108	11	70	study	study	NOUN
fnp-6108	11	71	per	per	ADP
fnp-6108	11	72	borghammer	borghammer	NOUN
fnp-6108	11	73	brain	brain	PROPN
fnp-6108	11	74	-	-	PUNCT
fnp-6108	11	75	first	first	ADV
fnp-6108	11	76	vs.	vs.	ADP
fnp-6108	11	77	body	body	NOUN
fnp-6108	11	78	-	-	PUNCT
fnp-6108	11	79	first	first	ADJ
fnp-6108	11	80	types	type	NOUN
fnp-6108	11	81	of	of	ADP
fnp-6108	11	82	lewy	lewy	ADJ
fnp-6108	11	83	body	body	NOUN
fnp-6108	11	84	disease	disease	NOUN
fnp-6108	11	85	–	–	PUNCT
fnp-6108	11	86	clinical	clinical	ADJ
fnp-6108	11	87	,	,	PUNCT
fnp-6108	11	88	imaging	imaging	NOUN
fnp-6108	11	89	,	,	PUNCT
fnp-6108	11	90	and	and	CCONJ
fnp-6108	11	91	postmortem	postmortem	PROPN
fnp-6108	11	92	data	data	PROPN
fnp-6108	11	93	emilia	emilia	PROPN
fnp-6108	11	94	brandt	brandt	PROPN
fnp-6108	11	95	et	et	PROPN
fnp-6108	11	96	al	al	PROPN
fnp-6108	11	97	gut	gut	VERB
fnp-6108	11	98	microbiome	microbiome	NOUN
fnp-6108	11	99	changes	change	NOUN
fnp-6108	11	100	in	in	ADP
fnp-6108	11	101	patients	patient	NOUN
fnp-6108	11	102	with	with	ADP
fnp-6108	11	103	idiopathic	idiopathic	ADJ
fnp-6108	11	104	normal	normal	ADJ
fnp-6108	11	105	pressure	pressure	NOUN
fnp-6108	11	106	hydrocephalus	hydrocephalus	X
fnp-6108	11	107	kia	kia	PROPN
fnp-6108	11	108	colangelo	colangelo	PROPN
fnp-6108	11	109	et	et	PROPN
fnp-6108	11	110	al	al	PROPN
fnp-6108	11	111	artificial	artificial	ADJ
fnp-6108	11	112	intelligence	intelligence	NOUN
fnp-6108	11	113	algorithm	algorithm	NOUN
fnp-6108	11	114	for	for	ADP
fnp-6108	11	115	studying	study	VERB
fnp-6108	11	116	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	11	117	in	in	ADP
fnp-6108	11	118	a	a	DET
fnp-6108	11	119	finnish	finnish	ADJ
fnp-6108	11	120	population	population	NOUN
fnp-6108	11	121	-	-	PUNCT
fnp-6108	11	122	based	base	VERB
fnp-6108	11	123	study	study	NOUN
fnp-6108	11	124	of	of	ADP
fnp-6108	11	125	the	the	DET
fnp-6108	11	126	oldest	oldest	ADV
fnp-6108	11	127	-	-	PUNCT
fnp-6108	11	128	old	old	ADJ
fnp-6108	11	129	(	(	PUNCT
fnp-6108	11	130	vantaa85	vantaa85	NOUN
fnp-6108	11	131	+	+	NOUN
fnp-6108	11	132	)	)	PUNCT
fnp-6108	11	133	henric	henric	NOUN
fnp-6108	11	134	ek	ek	PROPN
fnp-6108	11	135	olofsson	olofsson	PROPN
fnp-6108	11	136	et	et	PROPN
fnp-6108	11	137	al	al	PROPN
fnp-6108	11	138	microvascular	microvascular	ADJ
fnp-6108	11	139	brain	brain	NOUN
fnp-6108	11	140	raspberries	raspberry	NOUN
fnp-6108	11	141	:	:	PUNCT
fnp-6108	11	142	a	a	DET
fnp-6108	11	143	clinicopathological	clinicopathological	ADJ
fnp-6108	11	144	study	study	NOUN
fnp-6108	11	145	elisabet	elisabet	PROPN
fnp-6108	11	146	englund	englund	PROPN
fnp-6108	11	147	et	et	PROPN
fnp-6108	11	148	al	al	PROPN
fnp-6108	11	149	cardiac	cardiac	PROPN
fnp-6108	11	150	alpha	alpha	PROPN
fnp-6108	11	151	-	-	PUNCT
fnp-6108	11	152	synuclein	synuclein	NOUN
fnp-6108	11	153	may	may	AUX
fnp-6108	11	154	promote	promote	VERB
fnp-6108	11	155	sudden	sudden	ADJ
fnp-6108	11	156	cardiac	cardiac	ADJ
fnp-6108	11	157	death	death	NOUN
fnp-6108	11	158	in	in	ADP
fnp-6108	11	159	cases	case	NOUN
fnp-6108	11	160	with	with	ADP
fnp-6108	11	161	lewy	lewy	ADJ
fnp-6108	11	162	body	body	NOUN
fnp-6108	11	163	disease	disease	NOUN
fnp-6108	11	164	benjamin	benjamin	PROPN
fnp-6108	11	165	englert	englert	PROPN
fnp-6108	11	166	et	et	PROPN
fnp-6108	11	167	al	al	PROPN
fnp-6108	11	168	ageing	age	VERB
fnp-6108	11	169	-	-	PUNCT
fnp-6108	11	170	related	relate	VERB
fnp-6108	11	171	tau	tau	NOUN
fnp-6108	11	172	astrogliopathy	astrogliopathy	ADJ
fnp-6108	11	173	in	in	ADP
fnp-6108	11	174	the	the	DET
fnp-6108	11	175	oldest	old	ADJ
fnp-6108	11	176	old	old	ADJ
fnp-6108	11	177	population	population	NOUN
fnp-6108	11	178	(	(	PUNCT
fnp-6108	11	179	vantaa	vantaa	NOUN
fnp-6108	11	180	85	85	NUM
fnp-6108	11	181	+	+	NUM
fnp-6108	11	182	)	)	PUNCT
fnp-6108	11	183	maria	maria	NOUN
fnp-6108	11	184	gotkiewicz	gotkiewicz	VERB
fnp-6108	11	185	et	et	PROPN
fnp-6108	11	186	al	al	PROPN
fnp-6108	11	187	3d	3d	PROPN
fnp-6108	11	188	microscopy	microscopy	NOUN
fnp-6108	11	189	unravels	unravel	VERB
fnp-6108	11	190	details	detail	NOUN
fnp-6108	11	191	in	in	ADP
fnp-6108	11	192	amyloid	amyloid	NOUN
fnp-6108	11	193	plaque	plaque	NOUN
fnp-6108	11	194	-	-	PUNCT
fnp-6108	11	195	microglia	microglia	NOUN
fnp-6108	11	196	interaction	interaction	NOUN
fnp-6108	11	197	in	in	ADP
fnp-6108	11	198	app	app	PROPN
fnp-6108	11	199	/	/	SYM
fnp-6108	11	200	ps1	ps1	NOUN
fnp-6108	11	201	mice	mouse	NOUN
fnp-6108	11	202	masafumi	masafumi	ADJ
fnp-6108	11	203	ihara	ihara	X
fnp-6108	11	204	et	et	PROPN
fnp-6108	11	205	al	al	PROPN
fnp-6108	11	206	cadasil	cadasil	PROPN
fnp-6108	11	207	,	,	PUNCT
fnp-6108	11	208	the	the	DET
fnp-6108	11	209	leading	lead	VERB
fnp-6108	11	210	genetic	genetic	ADJ
fnp-6108	11	211	cause	cause	NOUN
fnp-6108	11	212	of	of	ADP
fnp-6108	11	213	small	small	ADJ
fnp-6108	11	214	vessel	vessel	NOUN
fnp-6108	11	215	disease	disease	NOUN
fnp-6108	11	216	karri	karri	PROPN
fnp-6108	11	217	kaivola	kaivola	PROPN
fnp-6108	11	218	et	et	PROPN
fnp-6108	11	219	al	al	PROPN
fnp-6108	11	220	genetic	genetic	ADJ
fnp-6108	11	221	subgroups	subgroup	NOUN
fnp-6108	11	222	in	in	ADP
fnp-6108	11	223	lewy	lewy	PROPN
fnp-6108	11	224	body	body	NOUN
fnp-6108	11	225	dementia	dementia	NOUN
fnp-6108	11	226	:	:	PUNCT
fnp-6108	11	227	the	the	DET
fnp-6108	11	228	influence	influence	NOUN
fnp-6108	11	229	of	of	ADP
fnp-6108	11	230	alzheimer	alzheimer	PROPN
fnp-6108	11	231	's	's	PART
fnp-6108	11	232	pathology	pathology	PROPN
fnp-6108	11	233	ville	ville	PROPN
fnp-6108	11	234	kivistö	kivistö	PROPN
fnp-6108	11	235	et	et	PROPN
fnp-6108	11	236	al	al	PROPN
fnp-6108	11	237	association	association	PROPN
fnp-6108	11	238	of	of	ADP
fnp-6108	11	239	cardiac	cardiac	ADJ
fnp-6108	11	240	sympathetic	sympathetic	ADJ
fnp-6108	11	241	denervation	denervation	NOUN
fnp-6108	11	242	with	with	ADP
fnp-6108	11	243	lewy	lewy	PROPN
fnp-6108	11	244	pathology	pathology	PROPN
fnp-6108	11	245	and	and	CCONJ
fnp-6108	11	246	its	its	PRON
fnp-6108	11	247	progression	progression	NOUN
fnp-6108	11	248	patterns	pattern	NOUN
fnp-6108	11	249	eloise	eloise	PROPN
fnp-6108	11	250	kok	kok	PROPN
fnp-6108	11	251	et	et	PROPN
fnp-6108	11	252	al	al	PROPN
fnp-6108	11	253	lewy	lewy	PROPN
fnp-6108	11	254	-	-	PUNCT
fnp-6108	11	255	related	relate	VERB
fnp-6108	11	256	pathology	pathology	NOUN
fnp-6108	11	257	in	in	ADP
fnp-6108	11	258	the	the	DET
fnp-6108	11	259	tampere	tampere	NOUN
fnp-6108	11	260	sudden	sudden	ADJ
fnp-6108	11	261	death	death	NOUN
fnp-6108	11	262	study	study	NOUN
fnp-6108	11	263	gabor	gabor	PROPN
fnp-6108	11	264	g.	g.	PROPN
fnp-6108	11	265	kovacs	kovacs	PROPN
fnp-6108	11	266	update	update	PROPN
fnp-6108	11	267	on	on	ADP
fnp-6108	11	268	tau	tau	PROPN
fnp-6108	11	269	-	-	PUNCT
fnp-6108	11	270	related	relate	VERB
fnp-6108	11	271	conditions	condition	NOUN
fnp-6108	11	272	maria	maria	PROPN
fnp-6108	11	273	k.	k.	PROPN
fnp-6108	11	274	lehtinen	lehtinen	PROPN
fnp-6108	11	275	investigating	investigate	VERB
fnp-6108	11	276	choroid	choroid	NOUN
fnp-6108	11	277	plexus	plexus	NOUN
fnp-6108	11	278	and	and	CCONJ
fnp-6108	11	279	cerebrospinal	cerebrospinal	ADJ
fnp-6108	11	280	fluid	fluid	ADJ
fnp-6108	11	281	roles	role	NOUN
fnp-6108	11	282	and	and	CCONJ
fnp-6108	11	283	functions	function	NOUN
fnp-6108	11	284	in	in	ADP
fnp-6108	11	285	neurologic	neurologic	ADJ
fnp-6108	11	286	disease	disease	NOUN
fnp-6108	11	287	sylwia	sylwia	PROPN
fnp-6108	11	288	libard	libard	PROPN
fnp-6108	11	289	et	et	PROPN
fnp-6108	11	290	al	al	PROPN
fnp-6108	11	291	neuropathologic	neuropathologic	PROPN
fnp-6108	11	292	change	change	NOUN
fnp-6108	11	293	in	in	ADP
fnp-6108	11	294	olfactory	olfactory	ADJ
fnp-6108	11	295	bulb	bulb	NOUN
fnp-6108	11	296	and	and	CCONJ
fnp-6108	11	297	nerve	nerve	NOUN
fnp-6108	11	298	of	of	ADP
fnp-6108	11	299	subjects	subject	NOUN
fnp-6108	11	300	with	with	ADP
fnp-6108	11	301	covid19	covid19	NOUN
fnp-6108	11	302	infection	infection	NOUN
fnp-6108	11	303	elizaveta	elizaveta	PROPN
fnp-6108	11	304	mikhailenko	mikhailenko	PROPN
fnp-6108	11	305	et	et	PROPN
fnp-6108	11	306	al	al	PROPN
fnp-6108	11	307	late	late	PROPN
fnp-6108	11	308	-	-	PUNCT
fnp-6108	11	309	nc	nc	PROPN
fnp-6108	11	310	in	in	ADP
fnp-6108	11	311	the	the	DET
fnp-6108	11	312	very	very	ADV
fnp-6108	11	313	elderly	elderly	ADJ
fnp-6108	11	314	–	–	PUNCT
fnp-6108	12	1	the	the	DET
fnp-6108	12	2	population	population	NOUN
fnp-6108	12	3	-	-	PUNCT
fnp-6108	12	4	based	base	VERB
fnp-6108	12	5	vantaa	vantaa	ADJ
fnp-6108	12	6	85	85	NUM
fnp-6108	12	7	+	+	NUM
fnp-6108	12	8	study	study	NOUN
fnp-6108	12	9	sara	sara	PROPN
fnp-6108	12	10	r.	r.	PROPN
fnp-6108	12	11	dunlop	dunlop	PROPN
fnp-6108	12	12	et	et	PROPN
fnp-6108	12	13	al	al	PROPN
fnp-6108	12	14	glial	glial	ADJ
fnp-6108	12	15	activation	activation	NOUN
fnp-6108	12	16	and	and	CCONJ
fnp-6108	12	17	tdp-43	tdp-43	NOUN
fnp-6108	12	18	differences	difference	NOUN
fnp-6108	12	19	among	among	ADP
fnp-6108	12	20	neuropathologic	neuropathologic	ADJ
fnp-6108	12	21	subtypes	subtype	NOUN
fnp-6108	12	22	of	of	ADP
fnp-6108	12	23	alzheimer	alzheimer	PROPN
fnp-6108	12	24	’s	’s	PART
fnp-6108	12	25	disease	disease	NOUN
fnp-6108	12	26	liisa	liisa	VERB
fnp-6108	12	27	myllykangas	myllykangas	NOUN
fnp-6108	12	28	neuropathological	neuropathological	ADJ
fnp-6108	12	29	subtypes	subtype	NOUN
fnp-6108	12	30	of	of	ADP
fnp-6108	12	31	lewy	lewy	ADJ
fnp-6108	12	32	body	body	NOUN
fnp-6108	12	33	disease	disease	NOUN
fnp-6108	12	34	:	:	PUNCT
fnp-6108	12	35	evidence	evidence	NOUN
fnp-6108	12	36	from	from	ADP
fnp-6108	12	37	a	a	DET
fnp-6108	12	38	population	population	NOUN
fnp-6108	12	39	-	-	PUNCT
fnp-6108	12	40	based	base	VERB
fnp-6108	12	41	study	study	NOUN
fnp-6108	12	42	pete	pete	PROPN
fnp-6108	12	43	nelson	nelson	PROPN
fnp-6108	12	44	disease	disease	NOUN
fnp-6108	12	45	-	-	PUNCT
fnp-6108	12	46	driving	drive	VERB
fnp-6108	12	47	mechanisms	mechanism	NOUN
fnp-6108	12	48	of	of	ADP
fnp-6108	12	49	late	late	ADJ
fnp-6108	12	50	-	-	PUNCT
fnp-6108	12	51	nc	nc	PROPN
fnp-6108	12	52	mithilesh	mithilesh	PROPN
fnp-6108	12	53	prakash	prakash	PROPN
fnp-6108	12	54	et	et	PROPN
fnp-6108	12	55	al	al	PROPN
fnp-6108	12	56	evaluating	evaluate	VERB
fnp-6108	12	57	the	the	DET
fnp-6108	12	58	impact	impact	NOUN
fnp-6108	12	59	of	of	ADP
fnp-6108	12	60	data	datum	NOUN
fnp-6108	12	61	harmonization	harmonization	NOUN
fnp-6108	12	62	on	on	ADP
fnp-6108	12	63	multi	multi	ADJ
fnp-6108	12	64	-	-	ADJ
fnp-6108	12	65	site	site	ADJ
fnp-6108	12	66	simulated	simulate	VERB
fnp-6108	12	67	neurodegeneration	neurodegeneration	NOUN
fnp-6108	12	68	dataset	dataset	NOUN
fnp-6108	12	69	analysis	analysis	NOUN
fnp-6108	12	70	eino	eino	NOUN
fnp-6108	12	71	solje	solje	X
fnp-6108	12	72	et	et	PROPN
fnp-6108	12	73	al	al	PROPN
fnp-6108	12	74	tdp-43	tdp-43	PROPN
fnp-6108	12	75	pathology	pathology	PROPN
fnp-6108	12	76	in	in	ADP
fnp-6108	12	77	frontal	frontal	ADJ
fnp-6108	12	78	cortical	cortical	ADJ
fnp-6108	12	79	brain	brain	NOUN
fnp-6108	12	80	biopsies	biopsy	NOUN
fnp-6108	12	81	of	of	ADP
fnp-6108	12	82	normal	normal	ADJ
fnp-6108	12	83	pressure	pressure	NOUN
fnp-6108	12	84	hydrocephalus	hydrocephalus	NOUN
fnp-6108	12	85	patients	patient	NOUN
fnp-6108	12	86	pernilla	pernilla	NOUN
fnp-6108	12	87	syrjä	syrjä	VERB
fnp-6108	12	88	et	et	NOUN
fnp-6108	12	89	al	al	PROPN
fnp-6108	12	90	cns	cns	PROPN
fnp-6108	12	91	amyloid	amyloid	NOUN
fnp-6108	12	92	patterns	pattern	NOUN
fnp-6108	12	93	in	in	ADP
fnp-6108	12	94	aging	age	VERB
fnp-6108	12	95	canines	canine	NOUN
fnp-6108	12	96	–	–	PUNCT
fnp-6108	12	97	a	a	DET
fnp-6108	12	98	pilotstudy	pilotstudy	NOUN
fnp-6108	12	99	regarding	regard	VERB
fnp-6108	12	100	neuropathology	neuropathology	NOUN
fnp-6108	12	101	in	in	ADP
fnp-6108	12	102	canine	canine	NOUN
fnp-6108	12	103	cognitive	cognitive	ADJ
fnp-6108	12	104	dysfunction	dysfunction	NOUN
fnp-6108	12	105	matti	matti	NOUN
fnp-6108	12	106	tyrväinen	tyrväinen	NOUN
fnp-6108	12	107	et	et	NOUN
fnp-6108	12	108	al	al	PROPN
fnp-6108	12	109	common	common	ADJ
fnp-6108	12	110	associations	association	NOUN
fnp-6108	12	111	of	of	ADP
fnp-6108	12	112	transcranial	transcranial	ADJ
fnp-6108	12	113	magnetic	magnetic	ADJ
fnp-6108	12	114	stimulation	stimulation	NOUN
fnp-6108	12	115	(	(	PUNCT
fnp-6108	12	116	tms	tms	PROPN
fnp-6108	12	117	)	)	PUNCT
fnp-6108	12	118	parameters	parameter	NOUN
fnp-6108	12	119	and	and	CCONJ
fnp-6108	12	120	behavioral	behavioral	ADJ
fnp-6108	12	121	symptoms	symptom	NOUN
fnp-6108	12	122	in	in	ADP
fnp-6108	12	123	different	different	ADJ
fnp-6108	12	124	neurocognitive	neurocognitive	ADJ
fnp-6108	12	125	diseases	disease	NOUN
fnp-6108	12	126	vladyslav	vladyslav	NOUN
fnp-6108	12	127	vadymovych	vadymovych	PROPN
fnp-6108	12	128	tkach	tkach	VERB
fnp-6108	12	129	et	et	PROPN
fnp-6108	12	130	al	al	PROPN
fnp-6108	12	131	digital	digital	ADJ
fnp-6108	12	132	morphological	morphological	ADJ
fnp-6108	12	133	profiling	profiling	NOUN
fnp-6108	12	134	reveals	reveal	VERB
fnp-6108	12	135	regionaland	regionaland	NOUN
fnp-6108	12	136	disease	disease	NOUN
fnp-6108	12	137	-	-	PUNCT
fnp-6108	12	138	specific	specific	ADJ
fnp-6108	12	139	differences	difference	NOUN
fnp-6108	12	140	of	of	ADP
fnp-6108	12	141	glial	glial	ADJ
fnp-6108	12	142	cells	cell	NOUN
fnp-6108	12	143	in	in	ADP
fnp-6108	12	144	neurodegenerative	neurodegenerative	ADJ
fnp-6108	12	145	proteinopathies	proteinopathie	NOUN
fnp-6108	12	146	jacob	jacob	PROPN
fnp-6108	12	147	vogel	vogel	PROPN
fnp-6108	12	148	et	et	PROPN
fnp-6108	12	149	al	al	PROPN
fnp-6108	12	150	an	an	DET
fnp-6108	12	151	update	update	NOUN
fnp-6108	12	152	on	on	ADP
fnp-6108	12	153	alzheimer	alzheimer	PROPN
fnp-6108	12	154	’s	’s	PART
fnp-6108	12	155	disease	disease	NOUN
fnp-6108	12	156	tau	tau	PROPN
fnp-6108	12	157	subtypes	subtype	NOUN
fnp-6108	12	158	:	:	PUNCT
fnp-6108	12	159	clinical	clinical	ADJ
fnp-6108	12	160	and	and	CCONJ
fnp-6108	12	161	biological	biological	ADJ
fnp-6108	12	162	insights	insight	NOUN
fnp-6108	12	163	david	david	PROPN
fnp-6108	12	164	a.	a.	NOUN
fnp-6108	12	165	wolk	wolk	PROPN
fnp-6108	12	166	clinical	clinical	ADJ
fnp-6108	12	167	and	and	CCONJ
fnp-6108	12	168	imaging	imaging	NOUN
fnp-6108	12	169	signatures	signature	NOUN
fnp-6108	12	170	of	of	ADP
fnp-6108	12	171	late	late	ADV
fnp-6108	12	172	:	:	PUNCT
fnp-6108	12	173	developing	develop	VERB
fnp-6108	12	174	a	a	DET
fnp-6108	12	175	diagnostic	diagnostic	ADJ
fnp-6108	12	176	framework	framework	NOUN
fnp-6108	12	177	    	    	SPACE
fnp-6108	12	178	free	free	ADJ
fnp-6108	12	179	neuropathol	neuropathol	NOUN
fnp-6108	12	180	5:30:5	5:30:5	NUM
fnp-6108	12	181	expanding	expand	VERB
fnp-6108	12	182	spectrum	spectrum	NOUN
fnp-6108	12	183	of	of	ADP
fnp-6108	12	184	dementia	dementia	NOUN
fnp-6108	12	185	disorders	disorder	NOUN
fnp-6108	12	186	irina	irina	PROPN
fnp-6108	12	187	alafuzoff1	alafuzoff1	PROPN
fnp-6108	12	188	uppsala	uppsala	PROPN
fnp-6108	12	189	university	university	PROPN
fnp-6108	12	190	hospital	hospital	NOUN
fnp-6108	12	191	,	,	PUNCT
fnp-6108	12	192	uppsala	uppsala	PROPN
fnp-6108	12	193	,	,	PUNCT
fnp-6108	12	194	sweden	sweden	VERB
fnp-6108	12	195	during	during	ADP
fnp-6108	12	196	the	the	DET
fnp-6108	12	197	last	last	ADJ
fnp-6108	12	198	40–50	40–50	NUM
fnp-6108	12	199	years	year	NOUN
fnp-6108	12	200	our	our	PRON
fnp-6108	12	201	knowledge	knowledge	NOUN
fnp-6108	12	202	regarding	regard	VERB
fnp-6108	12	203	aging	age	VERB
fnp-6108	12	204	related	relate	VERB
fnp-6108	12	205	cognitive	cognitive	ADJ
fnp-6108	12	206	impairment	impairment	NOUN
fnp-6108	12	207	has	have	AUX
fnp-6108	12	208	evolved	evolve	VERB
fnp-6108	12	209	significantly	significantly	ADV
fnp-6108	12	210	.	.	PUNCT
fnp-6108	13	1	in	in	ADP
fnp-6108	13	2	80s	80	NOUN
fnp-6108	13	3	clinicians	clinician	NOUN
fnp-6108	13	4	primarily	primarily	ADV
fnp-6108	13	5	referred	refer	VERB
fnp-6108	13	6	to	to	ADP
fnp-6108	13	7	a	a	DET
fnp-6108	13	8	senile	senile	ADJ
fnp-6108	13	9	dementia	dementia	NOUN
fnp-6108	13	10	,	,	PUNCT
fnp-6108	13	11	a	a	DET
fnp-6108	13	12	malady	malady	NOUN
fnp-6108	13	13	of	of	ADP
fnp-6108	13	14	the	the	DET
fnp-6108	13	15	aged	age	VERB
fnp-6108	13	16	.	.	PUNCT
fnp-6108	14	1	the	the	DET
fnp-6108	14	2	cause	cause	NOUN
fnp-6108	14	3	of	of	ADP
fnp-6108	14	4	this	this	DET
fnp-6108	14	5	disease	disease	NOUN
fnp-6108	14	6	was	be	AUX
fnp-6108	14	7	mostly	mostly	ADV
fnp-6108	14	8	unknown	unknown	ADJ
fnp-6108	14	9	.	.	PUNCT
fnp-6108	15	1	first	first	ADJ
fnp-6108	15	2	international	international	ADJ
fnp-6108	15	3	conference	conference	NOUN
fnp-6108	15	4	on	on	ADP
fnp-6108	15	5	alzheimer	alzheimer	PROPN
fnp-6108	15	6	's	's	PART
fnp-6108	15	7	disease	disease	NOUN
fnp-6108	15	8	and	and	CCONJ
fnp-6108	15	9	related	related	ADJ
fnp-6108	15	10	disorders	disorder	NOUN
fnp-6108	15	11	was	be	AUX
fnp-6108	15	12	organized	organize	VERB
fnp-6108	15	13	by	by	ADP
fnp-6108	15	14	professors	professor	NOUN
fnp-6108	15	15	khalid	khalid	PROPN
fnp-6108	15	16	iqbal	iqbal	PROPN
fnp-6108	15	17	,	,	PUNCT
fnp-6108	15	18	henry	henry	PROPN
fnp-6108	15	19	wisniewski	wisniewski	PROPN
fnp-6108	15	20	and	and	CCONJ
fnp-6108	15	21	bengt	bengt	PROPN
fnp-6108	15	22	winblad	winblad	VERB
fnp-6108	15	23	in	in	ADP
fnp-6108	15	24	1988	1988	NUM
fnp-6108	15	25	in	in	ADP
fnp-6108	15	26	las	las	PROPN
fnp-6108	15	27	vegas	vegas	PROPN
fnp-6108	15	28	,	,	PUNCT
fnp-6108	15	29	usa	usa	PROPN
fnp-6108	15	30	.	.	PUNCT
fnp-6108	16	1	the	the	DET
fnp-6108	16	2	total	total	ADJ
fnp-6108	16	3	number	number	NOUN
fnp-6108	16	4	of	of	ADP
fnp-6108	16	5	participants	participant	NOUN
fnp-6108	16	6	was	be	AUX
fnp-6108	16	7	quite	quite	ADV
fnp-6108	16	8	sparse	sparse	ADJ
fnp-6108	16	9	,	,	PUNCT
fnp-6108	16	10	most	most	ADJ
fnp-6108	16	11	being	be	AUX
fnp-6108	16	12	clinicians	clinician	NOUN
fnp-6108	16	13	and	and	CCONJ
fnp-6108	16	14	neuropathologist	neuropathologist	NOUN
fnp-6108	16	15	.	.	PUNCT
fnp-6108	17	1	at	at	ADP
fnp-6108	17	2	this	this	DET
fnp-6108	17	3	time	time	NOUN
fnp-6108	17	4	from	from	ADP
fnp-6108	17	5	the	the	DET
fnp-6108	17	6	view	view	NOUN
fnp-6108	17	7	of	of	ADP
fnp-6108	17	8	a	a	DET
fnp-6108	17	9	neuropathologist	neuropathologist	NOUN
fnp-6108	17	10	the	the	DET
fnp-6108	17	11	primary	primary	ADJ
fnp-6108	17	12	topics	topic	NOUN
fnp-6108	17	13	discussed	discuss	VERB
fnp-6108	17	14	were	be	AUX
fnp-6108	17	15	1	1	NUM
fnp-6108	17	16	.	.	PUNCT
fnp-6108	18	1	how	how	SCONJ
fnp-6108	18	2	many	many	ADJ
fnp-6108	18	3	plaques	plaque	NOUN
fnp-6108	18	4	are	be	AUX
fnp-6108	18	5	needed	need	VERB
fnp-6108	18	6	for	for	ADP
fnp-6108	18	7	a	a	DET
fnp-6108	18	8	diagnosis	diagnosis	NOUN
fnp-6108	18	9	of	of	ADP
fnp-6108	18	10	alzheimer	alzheimer	PROPN
fnp-6108	18	11	’s	’s	PART
fnp-6108	18	12	disease	disease	NOUN
fnp-6108	18	13	and	and	CCONJ
fnp-6108	18	14	2	2	NUM
fnp-6108	18	15	.	.	NOUN
fnp-6108	18	16	which	which	PRON
fnp-6108	18	17	is	be	AUX
fnp-6108	18	18	the	the	DET
fnp-6108	18	19	primary	primary	ADJ
fnp-6108	18	20	lesion	lesion	NOUN
fnp-6108	18	21	seen	see	VERB
fnp-6108	18	22	in	in	ADP
fnp-6108	18	23	the	the	DET
fnp-6108	18	24	brain	brain	NOUN
fnp-6108	18	25	,	,	PUNCT
fnp-6108	18	26	amyloid	amyloid	NOUN
fnp-6108	18	27	β	β	NOUN
fnp-6108	18	28	-	-	NOUN
fnp-6108	18	29	protein	protein	NOUN
fnp-6108	18	30	or	or	CCONJ
fnp-6108	18	31	hyperphosphorylated	hyperphosphorylate	VERB
fnp-6108	18	32	τ	τ	X
fnp-6108	18	33	?	?	PUNCT
fnp-6108	18	34	currently	currently	ADV
fnp-6108	18	35	,	,	PUNCT
fnp-6108	18	36	several	several	ADJ
fnp-6108	18	37	different	different	ADJ
fnp-6108	18	38	conferences	conference	NOUN
fnp-6108	18	39	are	be	AUX
fnp-6108	18	40	organized	organize	VERB
fnp-6108	18	41	yearly	yearly	ADV
fnp-6108	18	42	with	with	ADP
fnp-6108	18	43	thousands	thousand	NOUN
fnp-6108	18	44	of	of	ADP
fnp-6108	18	45	participants	participant	NOUN
fnp-6108	18	46	from	from	ADP
fnp-6108	18	47	various	various	ADJ
fnp-6108	18	48	fields	field	NOUN
fnp-6108	18	49	of	of	ADP
fnp-6108	18	50	neuroscience	neuroscience	NOUN
fnp-6108	18	51	.	.	PUNCT
fnp-6108	19	1	our	our	PRON
fnp-6108	19	2	knowledge	knowledge	NOUN
fnp-6108	19	3	regarding	regard	VERB
fnp-6108	19	4	the	the	DET
fnp-6108	19	5	neuropathology	neuropathology	NOUN
fnp-6108	19	6	seen	see	VERB
fnp-6108	19	7	in	in	ADP
fnp-6108	19	8	subjects	subject	NOUN
fnp-6108	19	9	with	with	ADP
fnp-6108	19	10	aging	age	VERB
fnp-6108	19	11	related	relate	VERB
fnp-6108	19	12	cognitive	cognitive	ADJ
fnp-6108	19	13	impairment	impairment	NOUN
fnp-6108	19	14	has	have	AUX
fnp-6108	19	15	evolved	evolve	VERB
fnp-6108	19	16	significantly	significantly	ADV
fnp-6108	19	17	.	.	PUNCT
fnp-6108	20	1	this	this	PRON
fnp-6108	20	2	has	have	AUX
fnp-6108	20	3	been	be	AUX
fnp-6108	20	4	facilitated	facilitate	VERB
fnp-6108	20	5	by	by	ADP
fnp-6108	20	6	the	the	DET
fnp-6108	20	7	identification	identification	NOUN
fnp-6108	20	8	of	of	ADP
fnp-6108	20	9	proteins	protein	NOUN
fnp-6108	20	10	that	that	PRON
fnp-6108	20	11	are	be	AUX
fnp-6108	20	12	altered	alter	VERB
fnp-6108	20	13	in	in	ADP
fnp-6108	20	14	the	the	DET
fnp-6108	20	15	brain	brain	NOUN
fnp-6108	20	16	of	of	ADP
fnp-6108	20	17	aged	aged	ADJ
fnp-6108	20	18	.	.	PUNCT
fnp-6108	21	1	the	the	DET
fnp-6108	21	2	insight	insight	NOUN
fnp-6108	21	3	that	that	SCONJ
fnp-6108	21	4	these	these	DET
fnp-6108	21	5	protein	protein	NOUN
fnp-6108	21	6	alterations	alteration	NOUN
fnp-6108	21	7	are	be	AUX
fnp-6108	21	8	initially	initially	ADV
fnp-6108	21	9	seen	see	VERB
fnp-6108	21	10	in	in	ADP
fnp-6108	21	11	certain	certain	ADJ
fnp-6108	21	12	brain	brain	NOUN
fnp-6108	21	13	regions	region	NOUN
fnp-6108	21	14	and	and	CCONJ
fnp-6108	21	15	progress	progress	NOUN
fnp-6108	21	16	following	follow	VERB
fnp-6108	21	17	certain	certain	ADJ
fnp-6108	21	18	neuroanatomical	neuroanatomical	ADJ
fnp-6108	21	19	connections	connection	NOUN
fnp-6108	21	20	has	have	AUX
fnp-6108	21	21	broadened	broaden	VERB
fnp-6108	21	22	our	our	PRON
fnp-6108	21	23	understanding	understanding	NOUN
fnp-6108	21	24	.	.	PUNCT
fnp-6108	22	1	it	it	PRON
fnp-6108	22	2	has	have	AUX
fnp-6108	22	3	also	also	ADV
fnp-6108	22	4	been	be	AUX
fnp-6108	22	5	acknowledged	acknowledge	VERB
fnp-6108	22	6	that	that	SCONJ
fnp-6108	22	7	in	in	ADP
fnp-6108	22	8	some	some	DET
fnp-6108	22	9	cases	case	NOUN
fnp-6108	22	10	the	the	DET
fnp-6108	22	11	disease	disease	NOUN
fnp-6108	22	12	is	be	AUX
fnp-6108	22	13	inherited	inherit	VERB
fnp-6108	22	14	based	base	VERB
fnp-6108	22	15	on	on	ADP
fnp-6108	22	16	genetic	genetic	ADJ
fnp-6108	22	17	alterations	alteration	NOUN
fnp-6108	22	18	leading	lead	VERB
fnp-6108	22	19	to	to	ADP
fnp-6108	22	20	ample	ample	ADJ
fnp-6108	22	21	use	use	NOUN
fnp-6108	22	22	of	of	ADP
fnp-6108	22	23	transgenic	transgenic	NOUN
fnp-6108	22	24	animals	animal	NOUN
fnp-6108	22	25	in	in	ADP
fnp-6108	22	26	research	research	NOUN
fnp-6108	22	27	.	.	PUNCT
fnp-6108	23	1	sadly	sadly	ADV
fnp-6108	23	2	,	,	PUNCT
fnp-6108	23	3	we	we	PRON
fnp-6108	23	4	still	still	ADV
fnp-6108	23	5	are	be	AUX
fnp-6108	23	6	quite	quite	ADV
fnp-6108	23	7	far	far	ADV
fnp-6108	23	8	from	from	ADP
fnp-6108	23	9	curative	curative	ADJ
fnp-6108	23	10	treatments	treatment	NOUN
fnp-6108	23	11	of	of	ADP
fnp-6108	23	12	these	these	DET
fnp-6108	23	13	maladies	malady	NOUN
fnp-6108	23	14	.	.	PUNCT
fnp-6108	24	1	recently	recently	ADV
fnp-6108	24	2	it	it	PRON
fnp-6108	24	3	has	have	AUX
fnp-6108	24	4	become	become	VERB
fnp-6108	24	5	clear	clear	ADJ
fnp-6108	24	6	that	that	SCONJ
fnp-6108	24	7	in	in	ADP
fnp-6108	24	8	many	many	ADJ
fnp-6108	24	9	aged	aged	ADJ
fnp-6108	24	10	,	,	PUNCT
fnp-6108	24	11	not	not	PART
fnp-6108	24	12	few	few	ADJ
fnp-6108	24	13	but	but	CCONJ
fnp-6108	24	14	rather	rather	ADV
fnp-6108	24	15	several	several	ADJ
fnp-6108	24	16	protein	protein	NOUN
fnp-6108	24	17	alterations	alteration	NOUN
fnp-6108	24	18	are	be	AUX
fnp-6108	24	19	to	to	PART
fnp-6108	24	20	be	be	AUX
fnp-6108	24	21	found	find	VERB
fnp-6108	24	22	in	in	ADP
fnp-6108	24	23	the	the	DET
fnp-6108	24	24	brain	brain	NOUN
fnp-6108	24	25	and	and	CCONJ
fnp-6108	24	26	even	even	ADV
fnp-6108	24	27	this	this	DET
fnp-6108	24	28	tendency	tendency	NOUN
fnp-6108	24	29	seems	seem	VERB
fnp-6108	24	30	to	to	PART
fnp-6108	24	31	increase	increase	VERB
fnp-6108	24	32	with	with	ADP
fnp-6108	24	33	age	age	NOUN
fnp-6108	24	34	.	.	PUNCT
fnp-6108	25	1	a	a	DET
fnp-6108	25	2	major	major	ADJ
fnp-6108	25	3	obstacle	obstacle	NOUN
fnp-6108	25	4	today	today	NOUN
fnp-6108	25	5	is	be	AUX
fnp-6108	25	6	limited	limited	ADJ
fnp-6108	25	7	number	number	NOUN
fnp-6108	25	8	of	of	ADP
fnp-6108	25	9	human	human	ADJ
fnp-6108	25	10	brain	brain	NOUN
fnp-6108	25	11	tissue	tissue	NOUN
fnp-6108	25	12	available	available	ADJ
fnp-6108	25	13	for	for	ADP
fnp-6108	25	14	research	research	NOUN
fnp-6108	25	15	.	.	PUNCT
fnp-6108	26	1	the	the	DET
fnp-6108	26	2	autopsy	autopsy	ADJ
fnp-6108	26	3	frequencies	frequency	NOUN
fnp-6108	26	4	are	be	AUX
fnp-6108	26	5	extremely	extremely	ADV
fnp-6108	26	6	low	low	ADJ
fnp-6108	26	7	and	and	CCONJ
fnp-6108	26	8	moreover	moreover	ADV
fnp-6108	26	9	the	the	DET
fnp-6108	26	10	brain	brain	NOUN
fnp-6108	26	11	is	be	AUX
fnp-6108	26	12	seldom	seldom	ADV
fnp-6108	26	13	assessed	assessed	ADJ
fnp-6108	26	14	postmortem	postmortem	NOUN
fnp-6108	26	15	.	.	PUNCT
fnp-6108	27	1	many	many	ADJ
fnp-6108	27	2	studies	study	NOUN
fnp-6108	27	3	can	can	AUX
fnp-6108	27	4	certainly	certainly	ADV
fnp-6108	27	5	be	be	AUX
fnp-6108	27	6	carried	carry	VERB
fnp-6108	27	7	out	out	ADP
fnp-6108	27	8	in	in	ADP
fnp-6108	27	9	animal	animal	NOUN
fnp-6108	27	10	models	model	NOUN
fnp-6108	27	11	.	.	PUNCT
fnp-6108	28	1	however	however	ADV
fnp-6108	28	2	,	,	PUNCT
fnp-6108	28	3	in	in	ADP
fnp-6108	28	4	line	line	NOUN
fnp-6108	28	5	with	with	ADP
fnp-6108	28	6	the	the	DET
fnp-6108	28	7	fruitful	fruitful	ADJ
fnp-6108	28	8	research	research	NOUN
fnp-6108	28	9	carried	carry	VERB
fnp-6108	28	10	out	out	ADP
fnp-6108	28	11	on	on	ADP
fnp-6108	28	12	tumors	tumor	NOUN
fnp-6108	28	13	,	,	PUNCT
fnp-6108	28	14	where	where	SCONJ
fnp-6108	28	15	the	the	DET
fnp-6108	28	16	use	use	NOUN
fnp-6108	28	17	of	of	ADP
fnp-6108	28	18	surgical	surgical	ADJ
fnp-6108	28	19	human	human	ADJ
fnp-6108	28	20	samples	sample	NOUN
fnp-6108	28	21	has	have	AUX
fnp-6108	28	22	led	lead	VERB
fnp-6108	28	23	to	to	ADP
fnp-6108	28	24	substantial	substantial	ADJ
fnp-6108	28	25	results	result	NOUN
fnp-6108	28	26	,	,	PUNCT
fnp-6108	28	27	also	also	ADV
fnp-6108	28	28	neurodegeneration	neurodegeneration	NOUN
fnp-6108	28	29	needs	need	VERB
fnp-6108	28	30	to	to	PART
fnp-6108	28	31	be	be	AUX
fnp-6108	28	32	studied	study	VERB
fnp-6108	28	33	in	in	ADP
fnp-6108	28	34	human	human	ADJ
fnp-6108	28	35	setting	setting	NOUN
fnp-6108	28	36	.	.	PUNCT
fnp-6108	29	1	this	this	PRON
fnp-6108	29	2	is	be	AUX
fnp-6108	29	3	certainly	certainly	ADV
fnp-6108	29	4	needed	need	VERB
fnp-6108	29	5	to	to	PART
fnp-6108	29	6	decrypt	decrypt	VERB
fnp-6108	29	7	these	these	DET
fnp-6108	29	8	complex	complex	ADJ
fnp-6108	29	9	diseases	disease	NOUN
fnp-6108	29	10	and	and	CCONJ
fnp-6108	29	11	hopefully	hopefully	ADV
fnp-6108	29	12	find	find	VERB
fnp-6108	29	13	efficient	efficient	ADJ
fnp-6108	29	14	treatment	treatment	NOUN
fnp-6108	29	15	strategies	strategy	NOUN
fnp-6108	29	16	improving	improve	VERB
fnp-6108	29	17	the	the	DET
fnp-6108	29	18	life	life	NOUN
fnp-6108	29	19	quality	quality	NOUN
fnp-6108	29	20	of	of	ADP
fnp-6108	29	21	the	the	DET
fnp-6108	29	22	affected	affected	ADJ
fnp-6108	29	23	subjects	subject	NOUN
fnp-6108	29	24	.	.	PUNCT
fnp-6108	29	25	  	  	SPACE
fnp-6108	30	1	free	free	ADJ
fnp-6108	30	2	neuropathol	neuropathol	NOUN
fnp-6108	30	3	5:30:6	5:30:6	PROPN
fnp-6108	30	4	rt	rt	PROPN
fnp-6108	30	5	-	-	PUNCT
fnp-6108	30	6	quic	quic	PROPN
fnp-6108	30	7	with	with	ADP
fnp-6108	30	8	universal	universal	ADJ
fnp-6108	30	9	control	control	NOUN
fnp-6108	30	10	fluid	fluid	NOUN
fnp-6108	30	11	:	:	PUNCT
fnp-6108	30	12	standardized	standardized	ADJ
fnp-6108	30	13	detection	detection	NOUN
fnp-6108	30	14	of	of	ADP
fnp-6108	30	15	alpha	alpha	NOUN
fnp-6108	30	16	-	-	PUNCT
fnp-6108	30	17	synucleinopathies	synucleinopathie	NOUN
fnp-6108	30	18	remarh	remarh	ADJ
fnp-6108	30	19	bsoul1	bsoul1	PROPN
fnp-6108	30	20	,	,	PUNCT
fnp-6108	30	21	eva	eva	PROPN
fnp-6108	30	22	løbner	løbner	PROPN
fnp-6108	30	23	lund1	lund1	PROPN
fnp-6108	30	24	,	,	PUNCT
fnp-6108	30	25	kristian	kristian	PROPN
fnp-6108	30	26	steen	steen	PROPN
fnp-6108	30	27	frederiksen1	frederiksen1	PROPN
fnp-6108	30	28	,	,	PUNCT
fnp-6108	30	29	sara	sara	PROPN
fnp-6108	30	30	brynhild	brynhild	PROPN
fnp-6108	30	31	winther	winther	PROPN
fnp-6108	30	32	bech2	bech2	PROPN
fnp-6108	30	33	,	,	PUNCT
fnp-6108	30	34	anja	anja	PROPN
fnp-6108	30	35	hviid	hviid	PROPN
fnp-6108	30	36	simonsen1	simonsen1	PROPN
fnp-6108	30	37	,	,	PUNCT
fnp-6108	30	38	kirsten	kirsten	PROPN
fnp-6108	30	39	svenstrup2	svenstrup2	PROPN
fnp-6108	30	40	,	,	PUNCT
fnp-6108	31	1	aušrinė	aušrinė	ADJ
fnp-6108	31	2	areškevičiūtė1	areškevičiūtė1	PROPN
fnp-6108	31	3	copenhagen	copenhagen	PROPN
fnp-6108	31	4	university	university	PROPN
fnp-6108	31	5	hospital	hospital	NOUN
fnp-6108	31	6	,	,	PUNCT
fnp-6108	31	7	rigshospitalet	rigshospitalet	PROPN
fnp-6108	31	8	,	,	PUNCT
fnp-6108	31	9	copenhagen	copenhagen	PROPN
fnp-6108	31	10	,	,	PUNCT
fnp-6108	31	11	denmark	denmark	NOUN
fnp-6108	31	12	bispebjerg	bispebjerg	PROPN
fnp-6108	31	13	and	and	CCONJ
fnp-6108	31	14	frederiksberg	frederiksberg	PROPN
fnp-6108	31	15	hospital	hospital	PROPN
fnp-6108	31	16	,	,	PUNCT
fnp-6108	31	17	copenhagen	copenhagen	PROPN
fnp-6108	31	18	,	,	PUNCT
fnp-6108	31	19	denmark	denmark	VERB
fnp-6108	31	20	we	we	PRON
fnp-6108	31	21	present	present	VERB
fnp-6108	31	22	a	a	DET
fnp-6108	31	23	csf	csf	ADJ
fnp-6108	31	24	rt	rt	NOUN
fnp-6108	31	25	-	-	PUNCT
fnp-6108	31	26	quic	quic	NOUN
fnp-6108	31	27	-	-	ADJ
fnp-6108	31	28	αsyn	αsyn	ADJ
fnp-6108	31	29	protocol	protocol	NOUN
fnp-6108	31	30	that	that	PRON
fnp-6108	31	31	is	be	AUX
fnp-6108	31	32	relatively	relatively	ADV
fnp-6108	31	33	easy	easy	ADJ
fnp-6108	31	34	to	to	PART
fnp-6108	31	35	adapt	adapt	VERB
fnp-6108	31	36	,	,	PUNCT
fnp-6108	31	37	performs	perform	VERB
fnp-6108	31	38	stably	stably	ADV
fnp-6108	31	39	,	,	PUNCT
fnp-6108	31	40	and	and	CCONJ
fnp-6108	31	41	enables	enable	VERB
fnp-6108	31	42	a	a	DET
fnp-6108	31	43	uniform	uniform	ADJ
fnp-6108	31	44	preparation	preparation	NOUN
fnp-6108	31	45	of	of	ADP
fnp-6108	31	46	both	both	DET
fnp-6108	31	47	sample	sample	NOUN
fnp-6108	31	48	and	and	CCONJ
fnp-6108	31	49	control	control	NOUN
fnp-6108	31	50	reactions	reaction	NOUN
fnp-6108	31	51	.	.	PUNCT
fnp-6108	32	1	we	we	PRON
fnp-6108	32	2	adopted	adopt	VERB
fnp-6108	32	3	and	and	CCONJ
fnp-6108	32	4	modified	modify	VERB
fnp-6108	32	5	rt	rt	PROPN
fnp-6108	32	6	-	-	PUNCT
fnp-6108	32	7	quic	quic	NOUN
fnp-6108	32	8	-	-	ADJ
fnp-6108	32	9	αsyn	αsyn	ADJ
fnp-6108	32	10	method	method	NOUN
fnp-6108	32	11	described	describe	VERB
fnp-6108	32	12	by	by	ADP
fnp-6108	32	13	others	other	NOUN
fnp-6108	32	14	.	.	PUNCT
fnp-6108	33	1	our	our	PRON
fnp-6108	33	2	protocol	protocol	NOUN
fnp-6108	33	3	's	's	PART
fnp-6108	33	4	sensitivity	sensitivity	NOUN
fnp-6108	33	5	and	and	CCONJ
fnp-6108	33	6	specificity	specificity	NOUN
fnp-6108	33	7	was	be	AUX
fnp-6108	33	8	estimated	estimate	VERB
fnp-6108	33	9	by	by	ADP
fnp-6108	33	10	testing	test	VERB
fnp-6108	33	11	csf	csf	ADJ
fnp-6108	33	12	samples	sample	NOUN
fnp-6108	33	13	from	from	ADP
fnp-6108	33	14	parkinson´s	parkinson´	NOUN
fnp-6108	33	15	(	(	PUNCT
fnp-6108	33	16	pd	pd	NOUN
fnp-6108	33	17	)	)	PUNCT
fnp-6108	33	18	(	(	PUNCT
fnp-6108	33	19	n	n	CCONJ
fnp-6108	33	20	 	 	SPACE
fnp-6108	33	21	=	=	NOUN
fnp-6108	33	22	 	 	SPACE
fnp-6108	33	23	12	12	NUM
fnp-6108	33	24	)	)	PUNCT
fnp-6108	33	25	,	,	PUNCT
fnp-6108	33	26	dementia	dementia	NOUN
fnp-6108	33	27	with	with	ADP
fnp-6108	33	28	lewy	lewy	NOUN
fnp-6108	33	29	-	-	PUNCT
fnp-6108	33	30	body	body	NOUN
fnp-6108	33	31	(	(	PUNCT
fnp-6108	33	32	dlb	dlb	NOUN
fnp-6108	33	33	)	)	PUNCT
fnp-6108	33	34	(	(	PUNCT
fnp-6108	33	35	n	n	CCONJ
fnp-6108	33	36	 	 	SPACE
fnp-6108	33	37	=	=	NOUN
fnp-6108	33	38	 	 	SPACE
fnp-6108	33	39	12	12	NUM
fnp-6108	33	40	)	)	PUNCT
fnp-6108	33	41	,	,	PUNCT
fnp-6108	33	42	alzheimer´s	alzheimer´s	PROPN
fnp-6108	33	43	(	(	PUNCT
fnp-6108	33	44	ad	ad	NOUN
fnp-6108	33	45	)	)	PUNCT
fnp-6108	33	46	(	(	PUNCT
fnp-6108	33	47	n	n	CCONJ
fnp-6108	33	48	 	 	SPACE
fnp-6108	33	49	=	=	NOUN
fnp-6108	33	50	 	 	SPACE
fnp-6108	33	51	12	12	NUM
fnp-6108	33	52	)	)	PUNCT
fnp-6108	33	53	,	,	PUNCT
fnp-6108	33	54	motor	motor	NOUN
fnp-6108	33	55	neuron	neuron	PROPN
fnp-6108	33	56	disease	disease	PROPN
fnp-6108	33	57	(	(	PUNCT
fnp-6108	33	58	mnd	mnd	PROPN
fnp-6108	33	59	)	)	PUNCT
fnp-6108	33	60	(	(	PUNCT
fnp-6108	33	61	n	n	CCONJ
fnp-6108	33	62	 	 	SPACE
fnp-6108	33	63	=	=	NOUN
fnp-6108	33	64	 	 	SPACE
fnp-6108	33	65	15	15	NUM
fnp-6108	33	66	)	)	PUNCT
fnp-6108	33	67	,	,	PUNCT
fnp-6108	33	68	multiple	multiple	ADJ
fnp-6108	33	69	system	system	NOUN
fnp-6108	33	70	atrophy	atrophy	NOUN
fnp-6108	33	71	(	(	PUNCT
fnp-6108	33	72	msa	msa	PROPN
fnp-6108	33	73	)	)	PUNCT
fnp-6108	33	74	(	(	PUNCT
fnp-6108	33	75	n	n	CCONJ
fnp-6108	33	76	 	 	SPACE
fnp-6108	33	77	=	=	NOUN
fnp-6108	33	78	 	 	SPACE
fnp-6108	33	79	18	18	NUM
fnp-6108	33	80	)	)	PUNCT
fnp-6108	33	81	and	and	CCONJ
fnp-6108	33	82	healthy	healthy	ADJ
fnp-6108	33	83	controls	control	NOUN
fnp-6108	33	84	(	(	PUNCT
fnp-6108	33	85	hc	hc	NOUN
fnp-6108	33	86	)	)	PUNCT
fnp-6108	33	87	(	(	PUNCT
fnp-6108	33	88	n	n	CCONJ
fnp-6108	33	89	 	 	SPACE
fnp-6108	33	90	=	=	NOUN
fnp-6108	33	91	 	 	SPACE
fnp-6108	33	92	12	12	NUM
fnp-6108	33	93	)	)	PUNCT
fnp-6108	33	94	.	.	PUNCT
fnp-6108	34	1	we	we	PRON
fnp-6108	34	2	tested	test	VERB
fnp-6108	34	3	3	3	NUM
fnp-6108	34	4	volumes	volume	NOUN
fnp-6108	34	5	of	of	ADP
fnp-6108	34	6	each	each	DET
fnp-6108	34	7	csf	csf	ADJ
fnp-6108	34	8	sample	sample	NOUN
fnp-6108	34	9	in	in	ADP
fnp-6108	34	10	quadruplicates	quadruplicate	NOUN
fnp-6108	34	11	to	to	PART
fnp-6108	34	12	assess	assess	VERB
fnp-6108	34	13	the	the	DET
fnp-6108	34	14	correlation	correlation	NOUN
fnp-6108	34	15	between	between	ADP
fnp-6108	34	16	added	add	VERB
fnp-6108	34	17	to	to	ADP
fnp-6108	34	18	the	the	DET
fnp-6108	34	19	reaction	reaction	NOUN
fnp-6108	34	20	csf	csf	VERB
fnp-6108	34	21	volume	volume	NOUN
fnp-6108	34	22	and	and	CCONJ
fnp-6108	34	23	αsyn	αsyn	NOUN
fnp-6108	34	24	seeding	seeding	NOUN
fnp-6108	34	25	efficiency	efficiency	NOUN
fnp-6108	34	26	.	.	PUNCT
fnp-6108	35	1	furthermore	furthermore	ADV
fnp-6108	35	2	,	,	PUNCT
fnp-6108	35	3	we	we	PRON
fnp-6108	35	4	developed	develop	VERB
fnp-6108	35	5	a	a	DET
fnp-6108	35	6	universal	universal	ADJ
fnp-6108	35	7	control	control	NOUN
fnp-6108	35	8	fluid	fluid	NOUN
fnp-6108	35	9	(	(	PUNCT
fnp-6108	35	10	ucf	ucf	PROPN
fnp-6108	35	11	)	)	PUNCT
fnp-6108	35	12	to	to	PART
fnp-6108	35	13	standardize	standardize	VERB
fnp-6108	35	14	rt	rt	PROPN
fnp-6108	35	15	-	-	PUNCT
fnp-6108	35	16	quic	quic	NOUN
fnp-6108	35	17	reaction	reaction	NOUN
fnp-6108	35	18	environment	environment	NOUN
fnp-6108	35	19	across	across	ADP
fnp-6108	35	20	all	all	DET
fnp-6108	35	21	samples	sample	NOUN
fnp-6108	35	22	and	and	CCONJ
fnp-6108	35	23	controls	control	NOUN
fnp-6108	35	24	by	by	ADP
fnp-6108	35	25	creating	create	VERB
fnp-6108	35	26	and	and	CCONJ
fnp-6108	35	27	testing	test	VERB
fnp-6108	35	28	various	various	ADJ
fnp-6108	35	29	ucf	ucf	PROPN
fnp-6108	35	30	compositions	composition	NOUN
fnp-6108	35	31	and	and	CCONJ
fnp-6108	35	32	sample	sample	NOUN
fnp-6108	35	33	/	/	SYM
fnp-6108	35	34	control	control	NOUN
fnp-6108	35	35	reaction	reaction	NOUN
fnp-6108	35	36	settings	setting	NOUN
fnp-6108	35	37	.	.	PUNCT
fnp-6108	36	1	our	our	PRON
fnp-6108	36	2	rt	rt	PROPN
fnp-6108	36	3	-	-	PUNCT
fnp-6108	36	4	quic	quic	NOUN
fnp-6108	36	5	-	-	NOUN
fnp-6108	36	6	αsyn	αsyn	NOUN
fnp-6108	36	7	performs	perform	VERB
fnp-6108	36	8	with	with	ADP
fnp-6108	36	9	>	>	X
fnp-6108	36	10	 	 	SPACE
fnp-6108	36	11	95	95	NUM
fnp-6108	36	12	 	 	SPACE
fnp-6108	36	13	%	%	NOUN
fnp-6108	36	14	sensitivity	sensitivity	NOUN
fnp-6108	36	15	for	for	ADP
fnp-6108	36	16	pd	pd	PROPN
fnp-6108	36	17	and	and	CCONJ
fnp-6108	36	18	dlb	dlb	PROPN
fnp-6108	36	19	,	,	PUNCT
fnp-6108	36	20	>	>	PUNCT
fnp-6108	36	21	 	 	SPACE
fnp-6108	36	22	95	95	NUM
fnp-6108	36	23	 	 	SPACE
fnp-6108	36	24	%	%	NOUN
fnp-6108	36	25	specificity	specificity	NOUN
fnp-6108	36	26	when	when	SCONJ
fnp-6108	36	27	compared	compare	VERB
fnp-6108	36	28	to	to	ADP
fnp-6108	36	29	ad	ad	NOUN
fnp-6108	36	30	and	and	CCONJ
fnp-6108	36	31	mnd	mnd	NOUN
fnp-6108	36	32	,	,	PUNCT
fnp-6108	36	33	and	and	CCONJ
fnp-6108	36	34	100	100	NUM
fnp-6108	36	35	 	 	SPACE
fnp-6108	36	36	%	%	NOUN
fnp-6108	36	37	specificity	specificity	NOUN
fnp-6108	36	38	when	when	SCONJ
fnp-6108	36	39	compared	compare	VERB
fnp-6108	36	40	to	to	ADP
fnp-6108	36	41	nc	nc	PROPN
fnp-6108	36	42	;	;	PUNCT
fnp-6108	36	43	whereas	whereas	SCONJ
fnp-6108	36	44	αsyn	αsyn	NOUN
fnp-6108	36	45	in	in	ADP
fnp-6108	36	46	msa	msa	PROPN
fnp-6108	36	47	samples	sample	NOUN
fnp-6108	36	48	was	be	AUX
fnp-6108	36	49	undetectable	undetectable	ADJ
fnp-6108	36	50	.	.	PUNCT
fnp-6108	37	1	we	we	PRON
fnp-6108	37	2	have	have	AUX
fnp-6108	37	3	defined	define	VERB
fnp-6108	37	4	a	a	DET
fnp-6108	37	5	ucf	ucf	NOUN
fnp-6108	37	6	composition	composition	NOUN
fnp-6108	37	7	that	that	PRON
fnp-6108	37	8	does	do	AUX
fnp-6108	37	9	not	not	PART
fnp-6108	37	10	compromise	compromise	VERB
fnp-6108	37	11	rt	rt	PROPN
fnp-6108	37	12	-	-	PUNCT
fnp-6108	37	13	quic	quic	NOUN
fnp-6108	37	14	reactions	reaction	NOUN
fnp-6108	37	15	'	'	PART
fnp-6108	37	16	effectivity	effectivity	NOUN
fnp-6108	37	17	and	and	CCONJ
fnp-6108	37	18	gives	give	VERB
fnp-6108	37	19	100	100	NUM
fnp-6108	37	20	 	 	SPACE
fnp-6108	37	21	%	%	NOUN
fnp-6108	37	22	sensitivity	sensitivity	NOUN
fnp-6108	37	23	and	and	CCONJ
fnp-6108	37	24	specificity	specificity	NOUN
fnp-6108	37	25	when	when	SCONJ
fnp-6108	37	26	comparing	compare	VERB
fnp-6108	37	27	unseeded	unseede	VERB
fnp-6108	37	28	ucf	ucf	NOUN
fnp-6108	37	29	and	and	CCONJ
fnp-6108	37	30	ucf	ucf	PROPN
fnp-6108	37	31	seeded	seed	VERB
fnp-6108	37	32	with	with	ADP
fnp-6108	37	33	patient	patient	ADJ
fnp-6108	37	34	material	material	NOUN
fnp-6108	37	35	.	.	PUNCT
fnp-6108	38	1	the	the	DET
fnp-6108	38	2	ucf	ucf	PROPN
fnp-6108	38	3	has	have	AUX
fnp-6108	38	4	also	also	ADV
fnp-6108	38	5	been	be	AUX
fnp-6108	38	6	tested	test	VERB
fnp-6108	38	7	as	as	ADP
fnp-6108	38	8	a	a	DET
fnp-6108	38	9	csf	csf	ADJ
fnp-6108	38	10	diluent	diluent	NOUN
fnp-6108	38	11	and	and	CCONJ
fnp-6108	38	12	is	be	AUX
fnp-6108	38	13	suitable	suitable	ADJ
fnp-6108	38	14	for	for	ADP
fnp-6108	38	15	broadening	broaden	VERB
fnp-6108	38	16	the	the	DET
fnp-6108	38	17	seeding	seed	VERB
fnp-6108	38	18	detection	detection	NOUN
fnp-6108	38	19	range	range	NOUN
fnp-6108	38	20	while	while	SCONJ
fnp-6108	38	21	keeping	keep	VERB
fnp-6108	38	22	the	the	DET
fnp-6108	38	23	assay	assay	PROPN
fnp-6108	38	24	environment	environment	NOUN
fnp-6108	38	25	uniform	uniform	NOUN
fnp-6108	38	26	.	.	PUNCT
fnp-6108	39	1	rt	rt	NOUN
fnp-6108	39	2	-	-	PUNCT
fnp-6108	39	3	quic	quic	NOUN
fnp-6108	39	4	-	-	NOUN
fnp-6108	39	5	αsyn	αsyn	NOUN
fnp-6108	39	6	is	be	AUX
fnp-6108	39	7	a	a	DET
fnp-6108	39	8	highly	highly	ADV
fnp-6108	39	9	sensitive	sensitive	ADJ
fnp-6108	39	10	and	and	CCONJ
fnp-6108	39	11	specific	specific	ADJ
fnp-6108	39	12	clinical	clinical	ADJ
fnp-6108	39	13	biomarker	biomarker	NOUN
fnp-6108	39	14	providing	provide	VERB
fnp-6108	39	15	pd	pd	PROPN
fnp-6108	39	16	/	/	SYM
fnp-6108	39	17	dlb	dlb	PROPN
fnp-6108	39	18	diagnosis	diagnosis	NOUN
fnp-6108	39	19	within	within	ADP
fnp-6108	39	20	48	48	NUM
fnp-6108	39	21	hours	hour	NOUN
fnp-6108	39	22	,	,	PUNCT
fnp-6108	39	23	and	and	CCONJ
fnp-6108	39	24	distinguishing	distinguish	VERB
fnp-6108	39	25	it	it	PRON
fnp-6108	39	26	from	from	ADP
fnp-6108	39	27	msa	msa	PROPN
fnp-6108	39	28	.	.	PUNCT
fnp-6108	40	1	rt	rt	PROPN
fnp-6108	40	2	-	-	PUNCT
fnp-6108	40	3	quic	quic	NOUN
fnp-6108	40	4	-	-	NOUN
fnp-6108	40	5	αsyn	αsyn	NOUN
fnp-6108	40	6	with	with	ADP
fnp-6108	40	7	ucf	ucf	PROPN
fnp-6108	40	8	has	have	VERB
fnp-6108	40	9	the	the	DET
fnp-6108	40	10	potential	potential	NOUN
fnp-6108	40	11	for	for	ADP
fnp-6108	40	12	a	a	DET
fnp-6108	40	13	standardized	standardized	ADJ
fnp-6108	40	14	diagnostic	diagnostic	ADJ
fnp-6108	40	15	protocol	protocol	NOUN
fnp-6108	40	16	across	across	ADP
fnp-6108	40	17	laboratories	laboratory	NOUN
fnp-6108	40	18	.	.	PUNCT
fnp-6108	40	19	  	  	SPACE
fnp-6108	41	1	free	free	ADJ
fnp-6108	41	2	neuropathol	neuropathol	NOUN
fnp-6108	41	3	5:30:7	5:30:7	NUM
fnp-6108	41	4	mixed	mixed	ADJ
fnp-6108	41	5	pathologies	pathology	NOUN
fnp-6108	41	6	of	of	ADP
fnp-6108	41	7	the	the	DET
fnp-6108	41	8	ageing	age	VERB
fnp-6108	41	9	brain	brain	NOUN
fnp-6108	41	10	johannes	johannes	PROPN
fnp-6108	41	11	attems1	attems1	PROPN
fnp-6108	41	12	translational	translational	ADJ
fnp-6108	41	13	and	and	CCONJ
fnp-6108	41	14	clinical	clinical	ADJ
fnp-6108	41	15	research	research	PROPN
fnp-6108	41	16	institute	institute	PROPN
fnp-6108	41	17	,	,	PUNCT
fnp-6108	41	18	newcastle	newcastle	PROPN
fnp-6108	41	19	university	university	PROPN
fnp-6108	41	20	,	,	PUNCT
fnp-6108	41	21	newcastle	newcastle	PROPN
fnp-6108	41	22	upon	upon	SCONJ
fnp-6108	41	23	tyne	tyne	PROPN
fnp-6108	41	24	,	,	PUNCT
fnp-6108	41	25	united	united	PROPN
fnp-6108	41	26	kingdom	kingdom	PROPN
fnp-6108	41	27	the	the	DET
fnp-6108	41	28	defining	define	VERB
fnp-6108	41	29	neuropathological	neuropathological	ADJ
fnp-6108	41	30	features	feature	NOUN
fnp-6108	41	31	of	of	ADP
fnp-6108	41	32	age	age	NOUN
fnp-6108	41	33	associated	associate	VERB
fnp-6108	41	34	neurodegenerative	neurodegenerative	ADJ
fnp-6108	41	35	diseases	disease	NOUN
fnp-6108	41	36	are	be	AUX
fnp-6108	41	37	aggregations	aggregation	NOUN
fnp-6108	41	38	of	of	ADP
fnp-6108	41	39	misfolded	misfolde	VERB
fnp-6108	41	40	proteins	protein	NOUN
fnp-6108	41	41	and	and	CCONJ
fnp-6108	41	42	the	the	DET
fnp-6108	41	43	neuropathological	neuropathological	ADJ
fnp-6108	41	44	diagnosis	diagnosis	NOUN
fnp-6108	41	45	is	be	AUX
fnp-6108	41	46	based	base	VERB
fnp-6108	41	47	on	on	ADP
fnp-6108	41	48	the	the	DET
fnp-6108	41	49	semiquantitative	semiquantitative	ADJ
fnp-6108	41	50	assessment	assessment	NOUN
fnp-6108	41	51	of	of	ADP
fnp-6108	41	52	these	these	DET
fnp-6108	41	53	misfolded	misfolde	VERB
fnp-6108	41	54	proteins	protein	NOUN
fnp-6108	41	55	that	that	PRON
fnp-6108	41	56	constitute	constitute	VERB
fnp-6108	41	57	the	the	DET
fnp-6108	41	58	neuropathological	neuropathological	ADJ
fnp-6108	41	59	hallmark	hallmark	ADJ
fnp-6108	41	60	lesion	lesion	NOUN
fnp-6108	41	61	for	for	ADP
fnp-6108	41	62	the	the	DET
fnp-6108	41	63	respective	respective	ADJ
fnp-6108	41	64	disease	disease	NOUN
fnp-6108	41	65	:	:	PUNCT
fnp-6108	41	66	e.g.	e.g.	ADV
fnp-6108	41	67	alzheimer	alzheimer	PROPN
fnp-6108	41	68	's	's	PART
fnp-6108	41	69	disease	disease	NOUN
fnp-6108	41	70	(	(	PUNCT
fnp-6108	41	71	ad	ad	NOUN
fnp-6108	41	72	)	)	PUNCT
fnp-6108	41	73	,	,	PUNCT
fnp-6108	41	74	amyloid	amyloid	NOUN
fnp-6108	41	75	-	-	PUNCT
fnp-6108	41	76	β	β	X
fnp-6108	41	77	(	(	PUNCT
fnp-6108	41	78	aβ	aβ	NOUN
fnp-6108	41	79	)	)	PUNCT
fnp-6108	41	80	hyperphosphorylated	hyperphosphorylate	VERB
fnp-6108	41	81	tau	tau	PROPN
fnp-6108	41	82	(	(	PUNCT
fnp-6108	41	83	tau	tau	PROPN
fnp-6108	41	84	)	)	PUNCT
fnp-6108	41	85	;	;	PUNCT
fnp-6108	42	1	lewy	lewy	PROPN
fnp-6108	42	2	body	body	NOUN
fnp-6108	42	3	diseases	disease	NOUN
fnp-6108	42	4	,	,	PUNCT
fnp-6108	42	5	α	α	X
fnp-6108	42	6	-	-	PUNCT
fnp-6108	42	7	synuclein	synuclein	NOUN
fnp-6108	42	8	(	(	PUNCT
fnp-6108	42	9	α	α	NOUN
fnp-6108	42	10	-	-	PUNCT
fnp-6108	42	11	syn	syn	NOUN
fnp-6108	42	12	)	)	PUNCT
fnp-6108	42	13	;	;	PUNCT
fnp-6108	42	14	limbic	limbic	ADJ
fnp-6108	42	15	-	-	PUNCT
fnp-6108	42	16	predominant	predominant	ADJ
fnp-6108	42	17	age	age	NOUN
fnp-6108	42	18	-	-	PUNCT
fnp-6108	42	19	related	relate	VERB
fnp-6108	42	20	tdp-43	tdp-43	NOUN
fnp-6108	42	21	encephalopathy	encephalopathy	ADJ
fnp-6108	42	22	(	(	PUNCT
fnp-6108	42	23	late	late	ADJ
fnp-6108	42	24	)	)	PUNCT
fnp-6108	42	25	,	,	PUNCT
fnp-6108	42	26	tdp-43	tdp-43	PROPN
fnp-6108	42	27	;	;	PUNCT
fnp-6108	42	28	frontotemporal	frontotemporal	ADJ
fnp-6108	42	29	lobar	lobar	ADJ
fnp-6108	42	30	degeneration	degeneration	NOUN
fnp-6108	42	31	,	,	PUNCT
fnp-6108	42	32	tau	tau	PROPN
fnp-6108	42	33	or	or	CCONJ
fnp-6108	42	34	tdp-43	tdp-43	PROPN
fnp-6108	42	35	or	or	CCONJ
fnp-6108	42	36	ubiquitin	ubiquitin	NOUN
fnp-6108	42	37	or	or	CCONJ
fnp-6108	42	38	fus	fus	NOUN
fnp-6108	42	39	.	.	PUNCT
fnp-6108	43	1	in	in	ADP
fnp-6108	43	2	addition	addition	NOUN
fnp-6108	43	3	,	,	PUNCT
fnp-6108	43	4	cerebrovascular	cerebrovascular	ADJ
fnp-6108	43	5	lesions	lesion	NOUN
fnp-6108	43	6	are	be	AUX
fnp-6108	43	7	assessed	assess	VERB
fnp-6108	43	8	for	for	ADP
fnp-6108	43	9	the	the	DET
fnp-6108	43	10	diagnosis	diagnosis	NOUN
fnp-6108	43	11	of	of	ADP
fnp-6108	43	12	cerebrovascular	cerebrovascular	ADJ
fnp-6108	43	13	disease	disease	NOUN
fnp-6108	43	14	.	.	PUNCT
fnp-6108	44	1	however	however	ADV
fnp-6108	44	2	,	,	PUNCT
fnp-6108	44	3	in	in	ADP
fnp-6108	44	4	brains	brain	NOUN
fnp-6108	44	5	of	of	ADP
fnp-6108	44	6	elderly	elderly	ADJ
fnp-6108	44	7	patients	patient	NOUN
fnp-6108	44	8	suffering	suffer	VERB
fnp-6108	44	9	from	from	ADP
fnp-6108	44	10	neurodegenerative	neurodegenerative	ADJ
fnp-6108	44	11	diseases	disease	NOUN
fnp-6108	44	12	mixed	mixed	ADJ
fnp-6108	44	13	pathologies	pathology	NOUN
fnp-6108	44	14	are	be	AUX
fnp-6108	44	15	usually	usually	ADV
fnp-6108	44	16	present	present	ADJ
fnp-6108	44	17	and	and	CCONJ
fnp-6108	44	18	various	various	ADJ
fnp-6108	44	19	amounts	amount	NOUN
fnp-6108	44	20	of	of	ADP
fnp-6108	44	21	neurodegenerative	neurodegenerative	ADJ
fnp-6108	44	22	and	and	CCONJ
fnp-6108	44	23	cerebrovascular	cerebrovascular	ADJ
fnp-6108	44	24	pathology	pathology	NOUN
fnp-6108	44	25	are	be	AUX
fnp-6108	44	26	frequently	frequently	ADV
fnp-6108	44	27	seen	see	VERB
fnp-6108	44	28	even	even	ADV
fnp-6108	44	29	in	in	ADP
fnp-6108	44	30	brains	brain	NOUN
fnp-6108	44	31	of	of	ADP
fnp-6108	44	32	non	non	ADJ
fnp-6108	44	33	-	-	ADJ
fnp-6108	44	34	demented	demented	ADJ
fnp-6108	44	35	elderly	elderly	ADJ
fnp-6108	44	36	.	.	PUNCT
fnp-6108	45	1	it	it	PRON
fnp-6108	45	2	does	do	AUX
fnp-6108	45	3	indeed	indeed	ADV
fnp-6108	45	4	become	become	VERB
fnp-6108	45	5	increasingly	increasingly	ADV
fnp-6108	45	6	clear	clear	ADJ
fnp-6108	45	7	that	that	SCONJ
fnp-6108	45	8	the	the	DET
fnp-6108	45	9	clinical	clinical	ADJ
fnp-6108	45	10	picture	picture	NOUN
fnp-6108	45	11	of	of	ADP
fnp-6108	45	12	dementia	dementia	NOUN
fnp-6108	45	13	in	in	ADP
fnp-6108	45	14	most	most	ADV
fnp-6108	45	15	aged	aged	ADJ
fnp-6108	45	16	patients	patient	NOUN
fnp-6108	45	17	results	result	VERB
fnp-6108	45	18	from	from	ADP
fnp-6108	45	19	mixed	mixed	ADJ
fnp-6108	45	20	pathologies	pathology	NOUN
fnp-6108	45	21	rather	rather	ADV
fnp-6108	45	22	than	than	ADP
fnp-6108	45	23	from	from	ADP
fnp-6108	45	24	one	one	NUM
fnp-6108	45	25	single	single	ADJ
fnp-6108	45	26	disease	disease	NOUN
fnp-6108	45	27	.	.	PUNCT
fnp-6108	46	1	importantly	importantly	ADV
fnp-6108	46	2	,	,	PUNCT
fnp-6108	46	3	these	these	DET
fnp-6108	46	4	mixed	mixed	ADJ
fnp-6108	46	5	pathologies	pathology	NOUN
fnp-6108	46	6	are	be	AUX
fnp-6108	46	7	often	often	ADV
fnp-6108	46	8	not	not	PART
fnp-6108	46	9	detected	detect	VERB
fnp-6108	46	10	clinically	clinically	ADV
fnp-6108	46	11	,	,	PUNCT
fnp-6108	46	12	which	which	PRON
fnp-6108	46	13	has	have	VERB
fnp-6108	46	14	a	a	DET
fnp-6108	46	15	detrimental	detrimental	ADJ
fnp-6108	46	16	impact	impact	NOUN
fnp-6108	46	17	on	on	ADP
fnp-6108	46	18	clinical	clinical	ADJ
fnp-6108	46	19	studies	study	NOUN
fnp-6108	46	20	since	since	SCONJ
fnp-6108	46	21	apparently	apparently	ADV
fnp-6108	46	22	homogeneous	homogeneous	ADJ
fnp-6108	46	23	study	study	NOUN
fnp-6108	46	24	cohorts	cohort	NOUN
fnp-6108	46	25	(	(	PUNCT
fnp-6108	46	26	e.g.	e.g.	ADV
fnp-6108	46	27	ad	ad	NOUN
fnp-6108	46	28	)	)	PUNCT
fnp-6108	46	29	are	be	AUX
fnp-6108	46	30	likely	likely	ADJ
fnp-6108	46	31	to	to	PART
fnp-6108	46	32	be	be	AUX
fnp-6108	46	33	heterogeneous	heterogeneous	ADJ
fnp-6108	46	34	(	(	PUNCT
fnp-6108	46	35	e.g.	e.g.	ADV
fnp-6108	46	36	ad	ad	NOUN
fnp-6108	46	37	only	only	ADV
fnp-6108	46	38	,	,	PUNCT
fnp-6108	46	39	ad	ad	NOUN
fnp-6108	46	40	and	and	CCONJ
fnp-6108	46	41	α	α	NOUN
fnp-6108	46	42	-	-	PUNCT
fnp-6108	46	43	syn	syn	NOUN
fnp-6108	46	44	,	,	PUNCT
fnp-6108	46	45	ad	ad	NOUN
fnp-6108	46	46	and	and	CCONJ
fnp-6108	46	47	tdp-43	tdp-43	NOUN
fnp-6108	46	48	)	)	PUNCT
fnp-6108	46	49	,	,	PUNCT
fnp-6108	46	50	which	which	PRON
fnp-6108	46	51	in	in	ADP
fnp-6108	46	52	turn	turn	NOUN
fnp-6108	46	53	introduces	introduce	VERB
fnp-6108	46	54	a	a	DET
fnp-6108	46	55	bias	bias	NOUN
fnp-6108	46	56	into	into	ADP
fnp-6108	46	57	therapeutic	therapeutic	ADJ
fnp-6108	46	58	trials	trial	NOUN
fnp-6108	46	59	and	and	CCONJ
fnp-6108	46	60	biomarker/	biomarker/	NUM
fnp-6108	46	61	imaging	imaging	NOUN
fnp-6108	46	62	studies	study	NOUN
fnp-6108	46	63	.	.	PUNCT
fnp-6108	47	1	hence	hence	ADV
fnp-6108	47	2	,	,	PUNCT
fnp-6108	47	3	wherever	wherever	SCONJ
fnp-6108	47	4	possible	possible	ADJ
fnp-6108	47	5	clinical	clinical	ADJ
fnp-6108	47	6	studies	study	NOUN
fnp-6108	47	7	should	should	AUX
fnp-6108	47	8	ideally	ideally	ADV
fnp-6108	47	9	involve	involve	VERB
fnp-6108	47	10	neuropathological	neuropathological	ADJ
fnp-6108	47	11	post	post	NOUN
fnp-6108	47	12	mortem	mortem	X
fnp-6108	47	13	assessment	assessment	NOUN
fnp-6108	47	14	to	to	PART
fnp-6108	47	15	correlate	correlate	VERB
fnp-6108	47	16	clinical	clinical	ADJ
fnp-6108	47	17	with	with	ADP
fnp-6108	47	18	neuropathological	neuropathological	ADJ
fnp-6108	47	19	data	datum	NOUN
fnp-6108	47	20	as	as	SCONJ
fnp-6108	47	21	this	this	PRON
fnp-6108	47	22	will	will	AUX
fnp-6108	47	23	enable	enable	VERB
fnp-6108	47	24	a	a	DET
fnp-6108	47	25	more	more	ADV
fnp-6108	47	26	accurate	accurate	ADJ
fnp-6108	47	27	stratification	stratification	NOUN
fnp-6108	47	28	of	of	ADP
fnp-6108	47	29	clinical	clinical	ADJ
fnp-6108	47	30	cohorts	cohort	NOUN
fnp-6108	47	31	according	accord	VERB
fnp-6108	47	32	to	to	ADP
fnp-6108	47	33	the	the	DET
fnp-6108	47	34	presence	presence	NOUN
fnp-6108	47	35	of	of	ADP
fnp-6108	47	36	multiple	multiple	ADJ
fnp-6108	47	37	pathologies	pathology	NOUN
fnp-6108	47	38	.	.	PUNCT
fnp-6108	48	1	this	this	PRON
fnp-6108	48	2	is	be	AUX
fnp-6108	48	3	crucial	crucial	ADJ
fnp-6108	48	4	for	for	ADP
fnp-6108	48	5	a	a	DET
fnp-6108	48	6	meaningful	meaningful	ADJ
fnp-6108	48	7	interpretation	interpretation	NOUN
fnp-6108	48	8	of	of	ADP
fnp-6108	48	9	clinical	clinical	ADJ
fnp-6108	48	10	data	datum	NOUN
fnp-6108	48	11	on	on	ADP
fnp-6108	48	12	biomarkers	biomarker	NOUN
fnp-6108	48	13	and	and	CCONJ
fnp-6108	48	14	therapeutic	therapeutic	ADJ
fnp-6108	48	15	effects	effect	NOUN
fnp-6108	48	16	.	.	PUNCT
fnp-6108	48	17	  	  	SPACE
fnp-6108	49	1	free	free	ADJ
fnp-6108	49	2	neuropathol	neuropathol	NOUN
fnp-6108	49	3	5:30:8	5:30:8	NUM
fnp-6108	49	4	nigral	nigral	ADJ
fnp-6108	49	5	neuroinflammation	neuroinflammation	NOUN
fnp-6108	49	6	and	and	CCONJ
fnp-6108	49	7	dopaminergic	dopaminergic	ADJ
fnp-6108	49	8	neurons	neuron	NOUN
fnp-6108	49	9	in	in	ADP
fnp-6108	49	10	pd	pd	PROPN
fnp-6108	49	11	,	,	PUNCT
fnp-6108	49	12	msa	msa	PROPN
fnp-6108	49	13	and	and	CCONJ
fnp-6108	49	14	psp	psp	PROPN
fnp-6108	49	15	:	:	PUNCT
fnp-6108	49	16	a	a	DET
fnp-6108	49	17	comparative	comparative	ADJ
fnp-6108	49	18	clinicopathological	clinicopathological	ADJ
fnp-6108	49	19	study	study	NOUN
fnp-6108	49	20	emmilotta	emmilotta	PROPN
fnp-6108	49	21	backman1,2	backman1,2	PROPN
fnp-6108	49	22	,	,	PUNCT
fnp-6108	49	23	maria	maria	PROPN
fnp-6108	49	24	gardberg3	gardberg3	PROPN
fnp-6108	49	25	,	,	PUNCT
fnp-6108	49	26	laura	laura	PROPN
fnp-6108	49	27	luntamo1,2	luntamo1,2	PROPN
fnp-6108	49	28	,	,	PUNCT
fnp-6108	49	29	markus	markus	PROPN
fnp-6108	49	30	peurla4	peurla4	NOUN
fnp-6108	49	31	,	,	PUNCT
fnp-6108	49	32	tero	tero	PROPN
fnp-6108	49	33	vahlberg5	vahlberg5	PROPN
fnp-6108	49	34	,	,	PUNCT
fnp-6108	49	35	per	per	ADP
fnp-6108	49	36	borghammer6,7	borghammer6,7	PROPN
fnp-6108	49	37	,	,	PUNCT
fnp-6108	49	38	nadia	nadia	PROPN
fnp-6108	49	39	stefanova8	stefanova8	PROPN
fnp-6108	49	40	,	,	PUNCT
fnp-6108	49	41	gregor	gregor	PROPN
fnp-6108	49	42	wenning8	wenning8	PROPN
fnp-6108	49	43	,	,	PUNCT
fnp-6108	49	44	valtteri	valtteri	NOUN
fnp-6108	49	45	kaasinen1,2	kaasinen1,2	PROPN
fnp-6108	49	46	clinical	clinical	ADJ
fnp-6108	49	47	neurosciences	neuroscience	NOUN
fnp-6108	49	48	,	,	PUNCT
fnp-6108	49	49	university	university	NOUN
fnp-6108	49	50	of	of	ADP
fnp-6108	49	51	turku	turku	PROPN
fnp-6108	49	52	,	,	PUNCT
fnp-6108	49	53	turku	turku	PROPN
fnp-6108	49	54	,	,	PUNCT
fnp-6108	49	55	finland	finland	PROPN
fnp-6108	49	56	neurocenter	neurocenter	PROPN
fnp-6108	49	57	,	,	PUNCT
fnp-6108	49	58	turku	turku	PROPN
fnp-6108	49	59	university	university	PROPN
fnp-6108	49	60	hospital	hospital	NOUN
fnp-6108	49	61	,	,	PUNCT
fnp-6108	49	62	turku	turku	PROPN
fnp-6108	49	63	,	,	PUNCT
fnp-6108	49	64	finland	finland	PROPN
fnp-6108	49	65	tyks	tyks	VERB
fnp-6108	49	66	laboratories	laboratory	NOUN
fnp-6108	49	67	,	,	PUNCT
fnp-6108	49	68	pathology	pathology	NOUN
fnp-6108	49	69	,	,	PUNCT
fnp-6108	49	70	turku	turku	PROPN
fnp-6108	49	71	university	university	PROPN
fnp-6108	49	72	hospital	hospital	NOUN
fnp-6108	49	73	and	and	CCONJ
fnp-6108	49	74	institute	institute	PROPN
fnp-6108	49	75	of	of	ADP
fnp-6108	49	76	biomedicine	biomedicine	NOUN
fnp-6108	49	77	,	,	PUNCT
fnp-6108	49	78	university	university	PROPN
fnp-6108	49	79	of	of	ADP
fnp-6108	49	80	turku	turku	PROPN
fnp-6108	49	81	,	,	PUNCT
fnp-6108	49	82	turku	turku	PROPN
fnp-6108	49	83	,	,	PUNCT
fnp-6108	49	84	finland	finland	PROPN
fnp-6108	49	85	institute	institute	PROPN
fnp-6108	49	86	of	of	ADP
fnp-6108	49	87	biomedicine	biomedicine	NOUN
fnp-6108	49	88	,	,	PUNCT
fnp-6108	49	89	university	university	PROPN
fnp-6108	49	90	of	of	ADP
fnp-6108	49	91	turku	turku	PROPN
fnp-6108	49	92	,	,	PUNCT
fnp-6108	49	93	turku	turku	PROPN
fnp-6108	49	94	,	,	PUNCT
fnp-6108	49	95	finland	finland	PROPN
fnp-6108	49	96	department	department	PROPN
fnp-6108	49	97	of	of	ADP
fnp-6108	49	98	biostatistics	biostatistic	NOUN
fnp-6108	49	99	,	,	PUNCT
fnp-6108	49	100	university	university	NOUN
fnp-6108	49	101	of	of	ADP
fnp-6108	49	102	turku	turku	PROPN
fnp-6108	49	103	and	and	CCONJ
fnp-6108	49	104	turku	turku	PROPN
fnp-6108	49	105	university	university	PROPN
fnp-6108	49	106	hospital	hospital	NOUN
fnp-6108	49	107	,	,	PUNCT
fnp-6108	49	108	turku	turku	PROPN
fnp-6108	49	109	,	,	PUNCT
fnp-6108	49	110	finland	finland	PROPN
fnp-6108	49	111	department	department	PROPN
fnp-6108	49	112	of	of	ADP
fnp-6108	49	113	nuclear	nuclear	ADJ
fnp-6108	49	114	medicine	medicine	NOUN
fnp-6108	49	115	and	and	CCONJ
fnp-6108	49	116	pet	pet	NOUN
fnp-6108	49	117	,	,	PUNCT
fnp-6108	49	118	aarhus	aarhus	PROPN
fnp-6108	49	119	university	university	PROPN
fnp-6108	49	120	hospital	hospital	NOUN
fnp-6108	49	121	,	,	PUNCT
fnp-6108	49	122	aarhus	aarhus	PROPN
fnp-6108	49	123	,	,	PUNCT
fnp-6108	49	124	denmark	denmark	PROPN
fnp-6108	49	125	department	department	NOUN
fnp-6108	49	126	of	of	ADP
fnp-6108	49	127	clinical	clinical	ADJ
fnp-6108	49	128	medicine	medicine	NOUN
fnp-6108	49	129	,	,	PUNCT
fnp-6108	49	130	aarhus	aarhus	PROPN
fnp-6108	49	131	university	university	PROPN
fnp-6108	49	132	,	,	PUNCT
fnp-6108	49	133	aarhus	aarhus	PROPN
fnp-6108	49	134	,	,	PUNCT
fnp-6108	49	135	denmark	denmark	NOUN
fnp-6108	49	136	division	division	NOUN
fnp-6108	49	137	of	of	ADP
fnp-6108	49	138	neurobiology	neurobiology	NOUN
fnp-6108	49	139	,	,	PUNCT
fnp-6108	49	140	department	department	NOUN
fnp-6108	49	141	of	of	ADP
fnp-6108	49	142	neurology	neurology	NOUN
fnp-6108	49	143	,	,	PUNCT
fnp-6108	49	144	medical	medical	ADJ
fnp-6108	49	145	university	university	NOUN
fnp-6108	49	146	innsbruck	innsbruck	PROPN
fnp-6108	49	147	,	,	PUNCT
fnp-6108	49	148	innsbruck	innsbruck	PROPN
fnp-6108	49	149	,	,	PUNCT
fnp-6108	49	150	austria	austria	PROPN
fnp-6108	49	151	objective	objective	NOUN
fnp-6108	49	152	:	:	PUNCT
fnp-6108	49	153	to	to	PART
fnp-6108	49	154	understand	understand	VERB
fnp-6108	49	155	the	the	DET
fnp-6108	49	156	complex	complex	ADJ
fnp-6108	49	157	interplay	interplay	NOUN
fnp-6108	49	158	between	between	ADP
fnp-6108	49	159	neuroinflammation	neuroinflammation	NOUN
fnp-6108	49	160	and	and	CCONJ
fnp-6108	49	161	clinical	clinical	ADJ
fnp-6108	49	162	characteristics	characteristic	NOUN
fnp-6108	49	163	in	in	ADP
fnp-6108	49	164	parkinson	parkinson	NOUN
fnp-6108	49	165	’s	’s	PART
fnp-6108	49	166	disease	disease	NOUN
fnp-6108	49	167	(	(	PUNCT
fnp-6108	49	168	pd	pd	NOUN
fnp-6108	49	169	)	)	PUNCT
fnp-6108	49	170	,	,	PUNCT
fnp-6108	49	171	multiple	multiple	ADJ
fnp-6108	49	172	system	system	NOUN
fnp-6108	49	173	atrophy	atrophy	NOUN
fnp-6108	49	174	(	(	PUNCT
fnp-6108	49	175	msa	msa	PROPN
fnp-6108	49	176	)	)	PUNCT
fnp-6108	49	177	and	and	CCONJ
fnp-6108	49	178	progressive	progressive	ADJ
fnp-6108	49	179	supranuclear	supranuclear	ADJ
fnp-6108	49	180	palsy	palsy	ADJ
fnp-6108	49	181	(	(	PUNCT
fnp-6108	49	182	psp	psp	NOUN
fnp-6108	49	183	)	)	PUNCT
fnp-6108	49	184	.	.	PUNCT
fnp-6108	50	1	materials	material	NOUN
fnp-6108	50	2	and	and	CCONJ
fnp-6108	50	3	methods	method	NOUN
fnp-6108	50	4	:	:	PUNCT
fnp-6108	50	5	postmortem	postmortem	NOUN
fnp-6108	50	6	neuropathological	neuropathological	ADJ
fnp-6108	50	7	samples	sample	NOUN
fnp-6108	50	8	were	be	AUX
fnp-6108	50	9	obtained	obtain	VERB
fnp-6108	50	10	from	from	ADP
fnp-6108	50	11	79	79	NUM
fnp-6108	50	12	individuals	individual	NOUN
fnp-6108	50	13	(	(	PUNCT
fnp-6108	50	14	pd	pd	NOUN
fnp-6108	50	15	,	,	PUNCT
fnp-6108	50	16	n	n	CCONJ
fnp-6108	50	17	 	 	SPACE
fnp-6108	50	18	=	=	NOUN
fnp-6108	50	19	 	 	SPACE
fnp-6108	50	20	38	38	NUM
fnp-6108	50	21	;	;	PUNCT
fnp-6108	50	22	psp	psp	NOUN
fnp-6108	50	23	,	,	PUNCT
fnp-6108	50	24	n	n	CCONJ
fnp-6108	50	25	 	 	SPACE
fnp-6108	50	26	=	=	NOUN
fnp-6108	50	27	 	 	SPACE
fnp-6108	50	28	15	15	NUM
fnp-6108	50	29	;	;	PUNCT
fnp-6108	50	30	msa	msa	PROPN
fnp-6108	50	31	,	,	PUNCT
fnp-6108	50	32	n	n	CCONJ
fnp-6108	50	33	 	 	SPACE
fnp-6108	50	34	=	=	NOUN
fnp-6108	50	35	 	 	SPACE
fnp-6108	50	36	14	14	NUM
fnp-6108	50	37	;	;	PUNCT
fnp-6108	50	38	and	and	CCONJ
fnp-6108	50	39	controls	control	NOUN
fnp-6108	50	40	,	,	PUNCT
fnp-6108	50	41	n	n	CCONJ
fnp-6108	50	42	 	 	SPACE
fnp-6108	50	43	=	=	NOUN
fnp-6108	50	44	 	 	SPACE
fnp-6108	50	45	12	12	NUM
fnp-6108	50	46	)	)	PUNCT
fnp-6108	50	47	.	.	PUNCT
fnp-6108	51	1	the	the	DET
fnp-6108	51	2	numbers	number	NOUN
fnp-6108	51	3	and	and	CCONJ
fnp-6108	51	4	densities	density	NOUN
fnp-6108	51	5	of	of	ADP
fnp-6108	51	6	snc	snc	PROPN
fnp-6108	51	7	tyrosine	tyrosine	PROPN
fnp-6108	51	8	hydroxylase	hydroxylase	PROPN
fnp-6108	51	9	(	(	PUNCT
fnp-6108	51	10	th)-positive	th)-positive	ADJ
fnp-6108	51	11	neurons	neuron	NOUN
fnp-6108	51	12	and	and	CCONJ
fnp-6108	51	13	t	t	NOUN
fnp-6108	51	14	cells	cell	NOUN
fnp-6108	51	15	(	(	PUNCT
fnp-6108	51	16	cd3	cd3	VERB
fnp-6108	51	17	+	+	PROPN
fnp-6108	51	18	,	,	PUNCT
fnp-6108	51	19	cd4	cd4	PROPN
fnp-6108	51	20	+	+	PROPN
fnp-6108	51	21	and	and	CCONJ
fnp-6108	51	22	cd8	cd8	PROPN
fnp-6108	51	23	+	+	PROPN
fnp-6108	51	24	)	)	PUNCT
fnp-6108	51	25	and	and	CCONJ
fnp-6108	51	26	iba1	iba1	NOUN
fnp-6108	51	27	expression	expression	NOUN
fnp-6108	51	28	(	(	PUNCT
fnp-6108	51	29	a	a	DET
fnp-6108	51	30	microglial	microglial	ADJ
fnp-6108	51	31	marker	marker	NOUN
fnp-6108	51	32	)	)	PUNCT
fnp-6108	51	33	were	be	AUX
fnp-6108	51	34	assessed	assess	VERB
fnp-6108	51	35	in	in	ADP
fnp-6108	51	36	both	both	CCONJ
fnp-6108	51	37	the	the	DET
fnp-6108	51	38	snc	snc	NOUN
fnp-6108	51	39	and	and	CCONJ
fnp-6108	51	40	crus	crus	NOUN
fnp-6108	51	41	cerebri	cerebri	NOUN
fnp-6108	51	42	.	.	PUNCT
fnp-6108	52	1	clinical	clinical	ADJ
fnp-6108	52	2	data	datum	NOUN
fnp-6108	52	3	were	be	AUX
fnp-6108	52	4	collected	collect	VERB
fnp-6108	52	5	from	from	ADP
fnp-6108	52	6	patient	patient	ADJ
fnp-6108	52	7	histories	history	NOUN
fnp-6108	52	8	.	.	PUNCT
fnp-6108	53	1	results	result	NOUN
fnp-6108	53	2	:	:	PUNCT
fnp-6108	53	3	psp	psp	NOUN
fnp-6108	53	4	patients	patient	NOUN
fnp-6108	53	5	had	have	VERB
fnp-6108	53	6	89	89	NUM
fnp-6108	53	7	-	-	SYM
fnp-6108	53	8	212	212	NUM
fnp-6108	53	9	 	 	SPACE
fnp-6108	53	10	%	%	NOUN
fnp-6108	53	11	more	more	ADJ
fnp-6108	53	12	nigral	nigral	NOUN
fnp-6108	53	13	cd3	cd3	VERB
fnp-6108	53	14	+	+	PROPN
fnp-6108	53	15	,	,	PUNCT
fnp-6108	53	16	cd4	cd4	PROPN
fnp-6108	53	17	+	+	PROPN
fnp-6108	53	18	,	,	PUNCT
fnp-6108	53	19	and	and	CCONJ
fnp-6108	53	20	cd8	cd8	PROPN
fnp-6108	53	21	+	+	PROPN
fnp-6108	53	22	t	t	PROPN
fnp-6108	53	23	cells	cell	NOUN
fnp-6108	53	24	than	than	ADP
fnp-6108	53	25	msa	msa	PROPN
fnp-6108	53	26	patients	patient	NOUN
fnp-6108	53	27	(	(	PUNCT
fnp-6108	53	28	p	p	X
fnp-6108	53	29	 	 	SPACE
fnp-6108	53	30	<	<	X
fnp-6108	53	31	 	 	SPACE
fnp-6108	53	32	0.04	0.04	NUM
fnp-6108	53	33	)	)	PUNCT
fnp-6108	53	34	,	,	PUNCT
fnp-6108	53	35	125–178	125–178	NUM
fnp-6108	53	36	 	 	SPACE
fnp-6108	53	37	%	%	NOUN
fnp-6108	53	38	more	more	ADV
fnp-6108	53	39	cd3	cd3	ADJ
fnp-6108	53	40	+	+	PROPN
fnp-6108	53	41	and	and	CCONJ
fnp-6108	53	42	cd4	cd4	PROPN
fnp-6108	53	43	+	+	PROPN
fnp-6108	53	44	t	t	NOUN
fnp-6108	53	45	cells	cell	NOUN
fnp-6108	53	46	than	than	ADP
fnp-6108	53	47	healthy	healthy	ADJ
fnp-6108	53	48	controls	control	NOUN
fnp-6108	53	49	(	(	PUNCT
fnp-6108	53	50	p	p	X
fnp-6108	53	51	 	 	SPACE
fnp-6108	53	52	<	<	X
fnp-6108	53	53	 	 	SPACE
fnp-6108	53	54	0.002	0.002	NUM
fnp-6108	53	55	)	)	PUNCT
fnp-6108	53	56	,	,	PUNCT
fnp-6108	53	57	and	and	CCONJ
fnp-6108	53	58	95	95	NUM
fnp-6108	53	59	 	 	SPACE
fnp-6108	53	60	%	%	NOUN
fnp-6108	53	61	more	more	ADV
fnp-6108	53	62	cd4	cd4	PROPN
fnp-6108	53	63	+	+	PROPN
fnp-6108	53	64	t	t	NOUN
fnp-6108	53	65	cells	cell	NOUN
fnp-6108	53	66	than	than	ADP
fnp-6108	53	67	pd	pd	NOUN
fnp-6108	53	68	patients	patient	NOUN
fnp-6108	53	69	(	(	PUNCT
fnp-6108	53	70	p	p	X
fnp-6108	53	71	 	 	SPACE
fnp-6108	53	72	=	=	NOUN
fnp-6108	53	73	 	 	SPACE
fnp-6108	53	74	0.001	0.001	NUM
fnp-6108	53	75	)	)	PUNCT
fnp-6108	53	76	.	.	PUNCT
fnp-6108	54	1	iba1	iba1	PROPN
fnp-6108	54	2	expression	expression	NOUN
fnp-6108	54	3	in	in	ADP
fnp-6108	54	4	the	the	DET
fnp-6108	54	5	snc	snc	NOUN
fnp-6108	54	6	was	be	AUX
fnp-6108	54	7	significantly	significantly	ADV
fnp-6108	54	8	higher	high	ADJ
fnp-6108	54	9	in	in	ADP
fnp-6108	54	10	pd	pd	PROPN
fnp-6108	54	11	patients	patient	NOUN
fnp-6108	54	12	than	than	ADP
fnp-6108	54	13	in	in	ADP
fnp-6108	54	14	msa	msa	PROPN
fnp-6108	54	15	patients	patient	NOUN
fnp-6108	54	16	(	(	PUNCT
fnp-6108	54	17	p	p	X
fnp-6108	54	18	 	 	SPACE
fnp-6108	54	19	=	=	NOUN
fnp-6108	54	20	 	 	SPACE
fnp-6108	54	21	0.004	0.004	NUM
fnp-6108	54	22	)	)	PUNCT
fnp-6108	54	23	,	,	PUNCT
fnp-6108	54	24	while	while	SCONJ
fnp-6108	54	25	no	no	DET
fnp-6108	54	26	significant	significant	ADJ
fnp-6108	54	27	variations	variation	NOUN
fnp-6108	54	28	were	be	AUX
fnp-6108	54	29	observed	observe	VERB
fnp-6108	54	30	across	across	ADP
fnp-6108	54	31	other	other	ADJ
fnp-6108	54	32	conditions	condition	NOUN
fnp-6108	54	33	.	.	PUNCT
fnp-6108	55	1	psp	psp	NOUN
fnp-6108	55	2	and	and	CCONJ
fnp-6108	55	3	msa	msa	PROPN
fnp-6108	55	4	patients	patient	NOUN
fnp-6108	55	5	had	have	VERB
fnp-6108	55	6	58–67	58–67	NUM
fnp-6108	55	7	 	 	SPACE
fnp-6108	55	8	%	%	NOUN
fnp-6108	55	9	fewer	few	ADJ
fnp-6108	55	10	snc	snc	PROPN
fnp-6108	55	11	th+	th+	NOUN
fnp-6108	55	12	neurons	neuron	NOUN
fnp-6108	55	13	than	than	ADP
fnp-6108	55	14	pd	pd	NOUN
fnp-6108	55	15	patients	patient	NOUN
fnp-6108	55	16	(	(	PUNCT
fnp-6108	55	17	p	p	X
fnp-6108	55	18	 	 	SPACE
fnp-6108	55	19	<	<	X
fnp-6108	55	20	 	 	SPACE
fnp-6108	55	21	0.05	0.05	NUM
fnp-6108	55	22	)	)	PUNCT
fnp-6108	55	23	and	and	CCONJ
fnp-6108	55	24	73–78	73–78	NUM
fnp-6108	55	25	 	 	SPACE
fnp-6108	55	26	%	%	NOUN
fnp-6108	55	27	fewer	few	ADJ
fnp-6108	55	28	than	than	ADP
fnp-6108	55	29	healthy	healthy	ADJ
fnp-6108	55	30	controls	control	NOUN
fnp-6108	55	31	(	(	PUNCT
fnp-6108	55	32	p	p	X
fnp-6108	55	33	 	 	SPACE
fnp-6108	55	34	<	<	X
fnp-6108	55	35	 	 	SPACE
fnp-6108	55	36	0.001	0.001	NUM
fnp-6108	55	37	)	)	PUNCT
fnp-6108	55	38	.	.	PUNCT
fnp-6108	56	1	disease	disease	NOUN
fnp-6108	56	2	duration	duration	NOUN
fnp-6108	56	3	from	from	ADP
fnp-6108	56	4	symptom	symptom	NOUN
fnp-6108	56	5	onset	onset	NOUN
fnp-6108	56	6	to	to	ADP
fnp-6108	56	7	death	death	NOUN
fnp-6108	56	8	was	be	AUX
fnp-6108	56	9	negatively	negatively	ADV
fnp-6108	56	10	associated	associate	VERB
fnp-6108	56	11	with	with	ADP
fnp-6108	56	12	snc	snc	PROPN
fnp-6108	56	13	cd3	cd3	PROPN
fnp-6108	56	14	+	+	PROPN
fnp-6108	56	15	t	t	NOUN
fnp-6108	56	16	-	-	PUNCT
fnp-6108	56	17	cell	cell	NOUN
fnp-6108	56	18	density	density	NOUN
fnp-6108	56	19	across	across	ADP
fnp-6108	56	20	groups	group	NOUN
fnp-6108	56	21	(	(	PUNCT
fnp-6108	56	22	p	p	X
fnp-6108	56	23	 	 	SPACE
fnp-6108	56	24	=	=	NOUN
fnp-6108	56	25	 	 	SPACE
fnp-6108	56	26	0.002	0.002	NUM
fnp-6108	56	27	)	)	PUNCT
fnp-6108	56	28	.	.	PUNCT
fnp-6108	57	1	nigral	nigral	ADJ
fnp-6108	57	2	dopaminergic	dopaminergic	ADJ
fnp-6108	57	3	neuronal	neuronal	ADJ
fnp-6108	57	4	density	density	NOUN
fnp-6108	57	5	correlated	correlate	VERB
fnp-6108	57	6	positively	positively	ADV
fnp-6108	57	7	with	with	ADP
fnp-6108	57	8	neuroinflammatory	neuroinflammatory	ADJ
fnp-6108	57	9	markers	marker	NOUN
fnp-6108	57	10	in	in	ADP
fnp-6108	57	11	pd	pd	PROPN
fnp-6108	57	12	.	.	PROPN
fnp-6108	57	13	conclusions	conclusion	NOUN
fnp-6108	57	14	:	:	PUNCT
fnp-6108	57	15	our	our	PRON
fnp-6108	57	16	findings	finding	NOUN
fnp-6108	57	17	reveal	reveal	VERB
fnp-6108	57	18	significant	significant	ADJ
fnp-6108	57	19	and	and	CCONJ
fnp-6108	57	20	distinctive	distinctive	ADJ
fnp-6108	57	21	t	t	NOUN
fnp-6108	57	22	-	-	PUNCT
fnp-6108	57	23	cell	cell	NOUN
fnp-6108	57	24	-	-	PUNCT
fnp-6108	57	25	mediated	mediate	VERB
fnp-6108	57	26	neuroinflammatory	neuroinflammatory	ADJ
fnp-6108	57	27	activity	activity	NOUN
fnp-6108	57	28	within	within	ADP
fnp-6108	57	29	the	the	DET
fnp-6108	57	30	snc	snc	NOUN
fnp-6108	57	31	in	in	ADP
fnp-6108	57	32	psp	psp	NOUN
fnp-6108	57	33	patients	patient	NOUN
fnp-6108	57	34	,	,	PUNCT
fnp-6108	57	35	and	and	CCONJ
fnp-6108	57	36	substantial	substantial	ADJ
fnp-6108	57	37	losses	loss	NOUN
fnp-6108	57	38	of	of	ADP
fnp-6108	57	39	snc	snc	NOUN
fnp-6108	57	40	dopaminergic	dopaminergic	ADJ
fnp-6108	57	41	neurons	neuron	NOUN
fnp-6108	57	42	in	in	ADP
fnp-6108	57	43	msa	msa	PROPN
fnp-6108	57	44	and	and	CCONJ
fnp-6108	57	45	psp	psp	NOUN
fnp-6108	57	46	compared	compare	VERB
fnp-6108	57	47	with	with	ADP
fnp-6108	57	48	pd	pd	PROPN
fnp-6108	57	49	patients	patient	NOUN
fnp-6108	57	50	.	.	PUNCT
fnp-6108	58	1	the	the	DET
fnp-6108	58	2	results	result	NOUN
fnp-6108	58	3	highlight	highlight	VERB
fnp-6108	58	4	distinct	distinct	ADJ
fnp-6108	58	5	neuroinflammatory	neuroinflammatory	NOUN
fnp-6108	58	6	patterns	pattern	NOUN
fnp-6108	58	7	in	in	ADP
fnp-6108	58	8	the	the	DET
fnp-6108	58	9	snc	snc	NOUN
fnp-6108	58	10	among	among	ADP
fnp-6108	58	11	different	different	ADJ
fnp-6108	58	12	parkinsonian	parkinsonian	ADJ
fnp-6108	58	13	disorders	disorder	NOUN
fnp-6108	58	14	,	,	PUNCT
fnp-6108	58	15	indicating	indicate	VERB
fnp-6108	58	16	potential	potential	ADJ
fnp-6108	58	17	implications	implication	NOUN
fnp-6108	58	18	for	for	ADP
fnp-6108	58	19	disease	disease	NOUN
fnp-6108	58	20	progression	progression	NOUN
fnp-6108	58	21	and	and	CCONJ
fnp-6108	58	22	therapeutic	therapeutic	ADJ
fnp-6108	58	23	strategies	strategy	NOUN
fnp-6108	58	24	.	.	PUNCT
fnp-6108	58	25	  	  	SPACE
fnp-6108	59	1	free	free	ADJ
fnp-6108	59	2	neuropathol	neuropathol	NOUN
fnp-6108	59	3	5:30:9	5:30:9	NUM
fnp-6108	59	4	brain	brain	NOUN
fnp-6108	59	5	-	-	PUNCT
fnp-6108	59	6	first	first	ADV
fnp-6108	59	7	vs.	vs.	ADP
fnp-6108	59	8	body	body	NOUN
fnp-6108	59	9	-	-	PUNCT
fnp-6108	59	10	first	first	ADJ
fnp-6108	59	11	types	type	NOUN
fnp-6108	59	12	of	of	ADP
fnp-6108	59	13	lewy	lewy	ADJ
fnp-6108	59	14	body	body	NOUN
fnp-6108	59	15	disease	disease	NOUN
fnp-6108	59	16	–	–	PUNCT
fnp-6108	59	17	clinical	clinical	ADJ
fnp-6108	59	18	,	,	PUNCT
fnp-6108	59	19	imaging	imaging	NOUN
fnp-6108	59	20	,	,	PUNCT
fnp-6108	59	21	and	and	CCONJ
fnp-6108	59	22	postmortem	postmortem	NOUN
fnp-6108	59	23	data	datum	NOUN
fnp-6108	59	24	per	per	ADP
fnp-6108	59	25	borghammer1	borghammer1	PROPN
fnp-6108	59	26	aarhus	aarhus	PROPN
fnp-6108	59	27	university	university	PROPN
fnp-6108	59	28	,	,	PUNCT
fnp-6108	59	29	aarhus	aarhus	PROPN
fnp-6108	59	30	,	,	PUNCT
fnp-6108	59	31	denmark	denmark	VERB
fnp-6108	59	32	within	within	ADP
fnp-6108	59	33	lewy	lewy	ADJ
fnp-6108	59	34	body	body	NOUN
fnp-6108	59	35	disorders	disorder	NOUN
fnp-6108	59	36	(	(	PUNCT
fnp-6108	59	37	lbd	lbd	PROPN
fnp-6108	59	38	)	)	PUNCT
fnp-6108	59	39	,	,	PUNCT
fnp-6108	59	40	accumulating	accumulate	VERB
fnp-6108	59	41	evidence	evidence	NOUN
fnp-6108	59	42	support	support	NOUN
fnp-6108	59	43	that	that	DET
fnp-6108	59	44	aggregation	aggregation	NOUN
fnp-6108	59	45	and	and	CCONJ
fnp-6108	59	46	neuron	neuron	NOUN
fnp-6108	59	47	-	-	PUNCT
fnp-6108	59	48	to	to	ADP
fnp-6108	59	49	-	-	PUNCT
fnp-6108	59	50	neuron	neuron	NOUN
fnp-6108	59	51	propagation	propagation	NOUN
fnp-6108	59	52	of	of	ADP
fnp-6108	59	53	alpha	alpha	NOUN
fnp-6108	59	54	-	-	PUNCT
fnp-6108	59	55	synuclein	synuclein	NOUN
fnp-6108	59	56	aggregates	aggregate	NOUN
fnp-6108	59	57	may	may	AUX
fnp-6108	59	58	be	be	AUX
fnp-6108	59	59	a	a	DET
fnp-6108	59	60	core	core	ADJ
fnp-6108	59	61	pathogenic	pathogenic	ADJ
fnp-6108	59	62	feature	feature	NOUN
fnp-6108	59	63	.	.	PUNCT
fnp-6108	60	1	the	the	DET
fnp-6108	60	2	brain	brain	NOUN
fnp-6108	60	3	-	-	PUNCT
fnp-6108	60	4	first	first	ADV
fnp-6108	60	5	vs.	vs.	ADP
fnp-6108	60	6	body	body	NOUN
fnp-6108	60	7	-	-	PUNCT
fnp-6108	60	8	first	first	ADV
fnp-6108	60	9	(	(	PUNCT
fnp-6108	60	10	bvb	bvb	NOUN
fnp-6108	60	11	)	)	PUNCT
fnp-6108	60	12	model	model	NOUN
fnp-6108	60	13	proposes	propose	VERB
fnp-6108	60	14	that	that	SCONJ
fnp-6108	60	15	,	,	PUNCT
fnp-6108	60	16	in	in	ADP
fnp-6108	60	17	most	most	ADJ
fnp-6108	60	18	lbd	lbd	PROPN
fnp-6108	60	19	patients	patient	NOUN
fnp-6108	60	20	,	,	PUNCT
fnp-6108	60	21	the	the	DET
fnp-6108	60	22	first	first	ADJ
fnp-6108	60	23	alpha	alpha	NOUN
fnp-6108	60	24	-	-	PUNCT
fnp-6108	60	25	synuclein	synuclein	NOUN
fnp-6108	60	26	aggregates	aggregate	NOUN
fnp-6108	60	27	initially	initially	ADV
fnp-6108	60	28	form	form	VERB
fnp-6108	60	29	in	in	ADP
fnp-6108	60	30	a	a	DET
fnp-6108	60	31	single	single	ADJ
fnp-6108	60	32	location	location	NOUN
fnp-6108	60	33	and	and	CCONJ
fnp-6108	60	34	then	then	ADV
fnp-6108	60	35	propagate	propagate	VERB
fnp-6108	60	36	through	through	ADP
fnp-6108	60	37	vulnerable	vulnerable	ADJ
fnp-6108	60	38	parts	part	NOUN
fnp-6108	60	39	of	of	ADP
fnp-6108	60	40	the	the	DET
fnp-6108	60	41	connectome	connectome	NOUN
fnp-6108	60	42	.	.	PUNCT
fnp-6108	61	1	the	the	DET
fnp-6108	61	2	most	most	ADV
fnp-6108	61	3	common	common	ADJ
fnp-6108	61	4	sites	site	NOUN
fnp-6108	61	5	of	of	ADP
fnp-6108	61	6	origin	origin	NOUN
fnp-6108	61	7	are	be	AUX
fnp-6108	61	8	the	the	DET
fnp-6108	61	9	olfactory	olfactory	ADJ
fnp-6108	61	10	system	system	NOUN
fnp-6108	61	11	and	and	CCONJ
fnp-6108	61	12	the	the	DET
fnp-6108	61	13	enteric	enteric	ADJ
fnp-6108	61	14	nervous	nervous	ADJ
fnp-6108	61	15	system	system	NOUN
fnp-6108	61	16	.	.	PUNCT
fnp-6108	62	1	the	the	DET
fnp-6108	62	2	bvb	bvb	NOUN
fnp-6108	62	3	model	model	NOUN
fnp-6108	62	4	suggests	suggest	VERB
fnp-6108	62	5	that	that	SCONJ
fnp-6108	62	6	when	when	SCONJ
fnp-6108	62	7	pathology	pathology	NOUN
fnp-6108	62	8	begins	begin	VERB
fnp-6108	62	9	in	in	ADP
fnp-6108	62	10	the	the	DET
fnp-6108	62	11	gut	gut	NOUN
fnp-6108	62	12	,	,	PUNCT
fnp-6108	62	13	it	it	PRON
fnp-6108	62	14	results	result	VERB
fnp-6108	62	15	in	in	ADP
fnp-6108	62	16	a	a	DET
fnp-6108	62	17	clinical	clinical	ADJ
fnp-6108	62	18	body	body	NOUN
fnp-6108	62	19	-	-	PUNCT
fnp-6108	62	20	first	first	ADJ
fnp-6108	62	21	subtype	subtype	NOUN
fnp-6108	62	22	marked	mark	VERB
fnp-6108	62	23	by	by	ADP
fnp-6108	62	24	early	early	ADJ
fnp-6108	62	25	autonomic	autonomic	ADJ
fnp-6108	62	26	symptoms	symptom	NOUN
fnp-6108	62	27	and	and	CCONJ
fnp-6108	62	28	rem	rem	VERB
fnp-6108	62	29	sleep	sleep	NOUN
fnp-6108	62	30	behavior	behavior	NOUN
fnp-6108	62	31	disorder	disorder	NOUN
fnp-6108	62	32	.	.	PUNCT
fnp-6108	63	1	on	on	ADP
fnp-6108	63	2	the	the	DET
fnp-6108	63	3	other	other	ADJ
fnp-6108	63	4	hand	hand	NOUN
fnp-6108	63	5	,	,	PUNCT
fnp-6108	63	6	when	when	SCONJ
fnp-6108	63	7	pathology	pathology	NOUN
fnp-6108	63	8	starts	start	VERB
fnp-6108	63	9	within	within	ADP
fnp-6108	63	10	the	the	DET
fnp-6108	63	11	olfactory	olfactory	ADJ
fnp-6108	63	12	system	system	NOUN
fnp-6108	63	13	,	,	PUNCT
fnp-6108	63	14	it	it	PRON
fnp-6108	63	15	leads	lead	VERB
fnp-6108	63	16	to	to	ADP
fnp-6108	63	17	a	a	DET
fnp-6108	63	18	brain	brain	NOUN
fnp-6108	63	19	-	-	PUNCT
fnp-6108	63	20	first	first	ADJ
fnp-6108	63	21	subtype	subtype	NOUN
fnp-6108	63	22	with	with	ADP
fnp-6108	63	23	fewer	few	ADJ
fnp-6108	63	24	non	non	ADJ
fnp-6108	63	25	-	-	ADJ
fnp-6108	63	26	motor	motor	ADJ
fnp-6108	63	27	symptoms	symptom	NOUN
fnp-6108	63	28	appearing	appear	VERB
fnp-6108	63	29	before	before	ADP
fnp-6108	63	30	diagnosis	diagnosis	NOUN
fnp-6108	63	31	.	.	PUNCT
fnp-6108	64	1	the	the	DET
fnp-6108	64	2	bvb	bvb	NOUN
fnp-6108	64	3	model	model	NOUN
fnp-6108	64	4	also	also	ADV
fnp-6108	64	5	predicts	predict	VERB
fnp-6108	64	6	that	that	SCONJ
fnp-6108	64	7	body	body	NOUN
fnp-6108	64	8	-	-	PUNCT
fnp-6108	64	9	first	first	ADJ
fnp-6108	64	10	lbd	lbd	PROPN
fnp-6108	64	11	patients	patient	NOUN
fnp-6108	64	12	tend	tend	VERB
fnp-6108	64	13	to	to	PART
fnp-6108	64	14	be	be	AUX
fnp-6108	64	15	older	old	ADJ
fnp-6108	64	16	,	,	PUNCT
fnp-6108	64	17	are	be	AUX
fnp-6108	64	18	more	more	ADV
fnp-6108	64	19	likely	likely	ADJ
fnp-6108	64	20	to	to	PART
fnp-6108	64	21	experience	experience	VERB
fnp-6108	64	22	symmetric	symmetric	ADJ
fnp-6108	64	23	dopaminergic	dopaminergic	ADJ
fnp-6108	64	24	degeneration	degeneration	NOUN
fnp-6108	64	25	,	,	PUNCT
fnp-6108	64	26	and	and	CCONJ
fnp-6108	64	27	face	face	VERB
fnp-6108	64	28	a	a	DET
fnp-6108	64	29	higher	high	ADJ
fnp-6108	64	30	risk	risk	NOUN
fnp-6108	64	31	of	of	ADP
fnp-6108	64	32	developing	develop	VERB
fnp-6108	64	33	dementia	dementia	NOUN
fnp-6108	64	34	compared	compare	VERB
fnp-6108	64	35	to	to	ADP
fnp-6108	64	36	brain	brain	NOUN
fnp-6108	64	37	-	-	PUNCT
fnp-6108	64	38	first	first	ADJ
fnp-6108	64	39	patients	patient	NOUN
fnp-6108	64	40	.	.	PUNCT
fnp-6108	65	1	thus	thus	ADV
fnp-6108	65	2	,	,	PUNCT
fnp-6108	65	3	the	the	DET
fnp-6108	65	4	bvb	bvb	NOUN
fnp-6108	65	5	model	model	NOUN
fnp-6108	65	6	proposes	propose	VERB
fnp-6108	65	7	that	that	SCONJ
fnp-6108	65	8	most	most	ADJ
fnp-6108	65	9	patients	patient	NOUN
fnp-6108	65	10	with	with	ADP
fnp-6108	65	11	dementia	dementia	NOUN
fnp-6108	65	12	with	with	ADP
fnp-6108	65	13	lewy	lewy	ADJ
fnp-6108	65	14	bodies	body	NOUN
fnp-6108	65	15	are	be	AUX
fnp-6108	65	16	body	body	NOUN
fnp-6108	65	17	-	-	PUNCT
fnp-6108	65	18	first	first	ADV
fnp-6108	65	19	,	,	PUNCT
fnp-6108	65	20	whereas	whereas	SCONJ
fnp-6108	65	21	most	most	ADJ
fnp-6108	65	22	patients	patient	NOUN
fnp-6108	65	23	with	with	ADP
fnp-6108	65	24	parkinson	parkinson	NOUN
fnp-6108	65	25	’s	’s	PART
fnp-6108	65	26	disease	disease	NOUN
fnp-6108	65	27	are	be	AUX
fnp-6108	65	28	brain	brain	NOUN
fnp-6108	65	29	-	-	PUNCT
fnp-6108	65	30	first	first	ADV
fnp-6108	65	31	.	.	PUNCT
fnp-6108	66	1	this	this	DET
fnp-6108	66	2	presentation	presentation	NOUN
fnp-6108	66	3	will	will	AUX
fnp-6108	66	4	outline	outline	VERB
fnp-6108	66	5	the	the	DET
fnp-6108	66	6	theoretical	theoretical	ADJ
fnp-6108	66	7	framework	framework	NOUN
fnp-6108	66	8	underlying	underlie	VERB
fnp-6108	66	9	the	the	DET
fnp-6108	66	10	bvb	bvb	NOUN
fnp-6108	66	11	model	model	NOUN
fnp-6108	66	12	and	and	CCONJ
fnp-6108	66	13	review	review	VERB
fnp-6108	66	14	supporting	support	VERB
fnp-6108	66	15	evidence	evidence	NOUN
fnp-6108	66	16	from	from	ADP
fnp-6108	66	17	clinical	clinical	ADJ
fnp-6108	66	18	,	,	PUNCT
fnp-6108	66	19	imaging	imaging	NOUN
fnp-6108	66	20	,	,	PUNCT
fnp-6108	66	21	animal	animal	NOUN
fnp-6108	66	22	,	,	PUNCT
fnp-6108	66	23	and	and	CCONJ
fnp-6108	66	24	postmortem	postmortem	NOUN
fnp-6108	66	25	studies	study	NOUN
fnp-6108	66	26	.	.	PUNCT
fnp-6108	66	27	  	  	SPACE
fnp-6108	67	1	free	free	ADJ
fnp-6108	67	2	neuropathol	neuropathol	NOUN
fnp-6108	67	3	5:30:10	5:30:10	NUM
fnp-6108	67	4	gut	gut	VERB
fnp-6108	67	5	microbiome	microbiome	NOUN
fnp-6108	67	6	changes	change	NOUN
fnp-6108	67	7	in	in	ADP
fnp-6108	67	8	patients	patient	NOUN
fnp-6108	67	9	with	with	ADP
fnp-6108	67	10	idiopathic	idiopathic	ADJ
fnp-6108	67	11	normal	normal	ADJ
fnp-6108	67	12	pressure	pressure	NOUN
fnp-6108	67	13	hydrocephalus	hydrocephalus	X
fnp-6108	67	14	emilia	emilia	PROPN
fnp-6108	67	15	brandt1,3	brandt1,3	PROPN
fnp-6108	67	16	,	,	PUNCT
fnp-6108	67	17	anne	anne	PROPN
fnp-6108	67	18	koivisto3,4,5	koivisto3,4,5	PROPN
fnp-6108	67	19	,	,	PUNCT
fnp-6108	67	20	pedro	pedro	PROPN
fnp-6108	67	21	pereira6	pereira6	PROPN
fnp-6108	67	22	,	,	PUNCT
fnp-6108	67	23	ella	ella	PROPN
fnp-6108	67	24	mustanoja7	mustanoja7	PROPN
fnp-6108	67	25	,	,	PUNCT
fnp-6108	67	26	petri	petri	ADJ
fnp-6108	67	27	auvinen7	auvinen7	PROPN
fnp-6108	67	28	,	,	PUNCT
fnp-6108	67	29	toni	toni	PROPN
fnp-6108	67	30	saari8	saari8	PROPN
fnp-6108	67	31	,	,	PUNCT
fnp-6108	67	32	juha	juha	PROPN
fnp-6108	67	33	-	-	PUNCT
fnp-6108	67	34	matti	matti	PROPN
fnp-6108	67	35	lehtola1,10	lehtola1,10	PROPN
fnp-6108	67	36	,	,	PUNCT
fnp-6108	67	37	sanna	sanna	PROPN
fnp-6108	67	38	hannonen1,3	hannonen1,3	PROPN
fnp-6108	67	39	,	,	PUNCT
fnp-6108	67	40	minna	minna	PROPN
fnp-6108	67	41	rusanen1,3	rusanen1,3	PROPN
fnp-6108	67	42	,	,	PUNCT
fnp-6108	67	43	ville	ville	PROPN
fnp-6108	67	44	leinonen2,3	leinonen2,3	PROPN
fnp-6108	67	45	,	,	PUNCT
fnp-6108	67	46	filip	filip	PROPN
fnp-6108	67	47	scheperjans6,9	scheperjans6,9	PROPN
fnp-6108	67	48	,	,	PUNCT
fnp-6108	67	49	virve	virve	VERB
fnp-6108	67	50	kärkkäinen2,3	kärkkäinen2,3	PROPN
fnp-6108	67	51	neurology	neurology	NOUN
fnp-6108	67	52	,	,	PUNCT
fnp-6108	67	53	institute	institute	NOUN
fnp-6108	67	54	of	of	ADP
fnp-6108	67	55	clinical	clinical	ADJ
fnp-6108	67	56	medicine	medicine	NOUN
fnp-6108	67	57	,	,	PUNCT
fnp-6108	67	58	school	school	NOUN
fnp-6108	67	59	of	of	ADP
fnp-6108	67	60	medicine	medicine	NOUN
fnp-6108	67	61	,	,	PUNCT
fnp-6108	67	62	university	university	NOUN
fnp-6108	67	63	of	of	ADP
fnp-6108	67	64	eastern	eastern	PROPN
fnp-6108	67	65	finland	finland	PROPN
fnp-6108	67	66	,	,	PUNCT
fnp-6108	67	67	kuopio	kuopio	PROPN
fnp-6108	67	68	,	,	PUNCT
fnp-6108	67	69	finland	finland	PROPN
fnp-6108	67	70	neurosurgery	neurosurgery	NOUN
fnp-6108	67	71	,	,	PUNCT
fnp-6108	67	72	institute	institute	NOUN
fnp-6108	67	73	of	of	ADP
fnp-6108	67	74	clinical	clinical	ADJ
fnp-6108	67	75	medicine	medicine	NOUN
fnp-6108	67	76	,	,	PUNCT
fnp-6108	67	77	school	school	NOUN
fnp-6108	67	78	of	of	ADP
fnp-6108	67	79	medicine	medicine	NOUN
fnp-6108	67	80	,	,	PUNCT
fnp-6108	67	81	university	university	NOUN
fnp-6108	67	82	of	of	ADP
fnp-6108	67	83	eastern	eastern	PROPN
fnp-6108	67	84	finland	finland	PROPN
fnp-6108	67	85	,	,	PUNCT
fnp-6108	67	86	kuopio	kuopio	PROPN
fnp-6108	67	87	,	,	PUNCT
fnp-6108	67	88	finland	finland	PROPN
fnp-6108	67	89	neurocenter	neurocenter	PROPN
fnp-6108	67	90	,	,	PUNCT
fnp-6108	67	91	kuopio	kuopio	PROPN
fnp-6108	67	92	university	university	NOUN
fnp-6108	67	93	hospital	hospital	NOUN
fnp-6108	67	94	,	,	PUNCT
fnp-6108	67	95	kuopio	kuopio	PROPN
fnp-6108	67	96	,	,	PUNCT
fnp-6108	67	97	finland	finland	PROPN
fnp-6108	67	98	department	department	PROPN
fnp-6108	67	99	of	of	ADP
fnp-6108	67	100	neurosciences	neuroscience	NOUN
fnp-6108	67	101	,	,	PUNCT
fnp-6108	67	102	faculty	faculty	NOUN
fnp-6108	67	103	of	of	ADP
fnp-6108	67	104	medicine	medicine	NOUN
fnp-6108	67	105	,	,	PUNCT
fnp-6108	67	106	university	university	PROPN
fnp-6108	67	107	of	of	ADP
fnp-6108	67	108	helsinki	helsinki	PROPN
fnp-6108	67	109	,	,	PUNCT
fnp-6108	67	110	helsinki	helsinki	PROPN
fnp-6108	67	111	,	,	PUNCT
fnp-6108	67	112	finland	finland	PROPN
fnp-6108	67	113	department	department	PROPN
fnp-6108	67	114	of	of	ADP
fnp-6108	67	115	geriatrics	geriatrics	PROPN
fnp-6108	67	116	,	,	PUNCT
fnp-6108	67	117	helsinki	helsinki	PROPN
fnp-6108	67	118	university	university	PROPN
fnp-6108	67	119	hospital	hospital	NOUN
fnp-6108	67	120	,	,	PUNCT
fnp-6108	67	121	helsinki	helsinki	PROPN
fnp-6108	67	122	,	,	PUNCT
fnp-6108	67	123	finland	finland	PROPN
fnp-6108	67	124	department	department	PROPN
fnp-6108	67	125	of	of	ADP
fnp-6108	67	126	neurology	neurology	PROPN
fnp-6108	67	127	,	,	PUNCT
fnp-6108	67	128	helsinki	helsinki	PROPN
fnp-6108	67	129	university	university	PROPN
fnp-6108	67	130	hospital	hospital	NOUN
fnp-6108	67	131	,	,	PUNCT
fnp-6108	67	132	helsinki	helsinki	PROPN
fnp-6108	67	133	,	,	PUNCT
fnp-6108	67	134	finland	finland	PROPN
fnp-6108	67	135	institute	institute	PROPN
fnp-6108	67	136	of	of	ADP
fnp-6108	67	137	biotechnology	biotechnology	NOUN
fnp-6108	67	138	,	,	PUNCT
fnp-6108	67	139	university	university	PROPN
fnp-6108	67	140	of	of	ADP
fnp-6108	67	141	helsinki	helsinki	PROPN
fnp-6108	67	142	,	,	PUNCT
fnp-6108	67	143	helsinki	helsinki	PROPN
fnp-6108	67	144	,	,	PUNCT
fnp-6108	67	145	finland	finland	PROPN
fnp-6108	67	146	institute	institute	PROPN
fnp-6108	67	147	for	for	ADP
fnp-6108	67	148	molecular	molecular	ADJ
fnp-6108	67	149	medicine	medicine	NOUN
fnp-6108	67	150	finland	finland	PROPN
fnp-6108	67	151	(	(	PUNCT
fnp-6108	67	152	fimm	fimm	NOUN
fnp-6108	67	153	)	)	PUNCT
fnp-6108	67	154	,	,	PUNCT
fnp-6108	67	155	helsinki	helsinki	PROPN
fnp-6108	67	156	institute	institute	PROPN
fnp-6108	67	157	of	of	ADP
fnp-6108	67	158	life	life	PROPN
fnp-6108	67	159	sciences	sciences	PROPN
fnp-6108	67	160	,	,	PUNCT
fnp-6108	67	161	university	university	NOUN
fnp-6108	67	162	of	of	ADP
fnp-6108	67	163	helsinki	helsinki	PROPN
fnp-6108	67	164	,	,	PUNCT
fnp-6108	67	165	helsinki	helsinki	PROPN
fnp-6108	67	166	,	,	PUNCT
fnp-6108	67	167	finland	finland	PROPN
fnp-6108	67	168	clinicum	clinicum	PROPN
fnp-6108	67	169	,	,	PUNCT
fnp-6108	67	170	university	university	PROPN
fnp-6108	67	171	of	of	ADP
fnp-6108	67	172	helsinki	helsinki	PROPN
fnp-6108	67	173	,	,	PUNCT
fnp-6108	67	174	helsinki	helsinki	PROPN
fnp-6108	67	175	,	,	PUNCT
fnp-6108	67	176	finland	finland	PROPN
fnp-6108	67	177	department	department	PROPN
fnp-6108	67	178	of	of	ADP
fnp-6108	67	179	psychiatry	psychiatry	PROPN
fnp-6108	67	180	,	,	PUNCT
fnp-6108	67	181	turku	turku	PROPN
fnp-6108	67	182	university	university	PROPN
fnp-6108	67	183	hospital	hospital	NOUN
fnp-6108	67	184	,	,	PUNCT
fnp-6108	67	185	turku	turku	PROPN
fnp-6108	67	186	,	,	PUNCT
fnp-6108	67	187	finland	finland	PROPN
fnp-6108	67	188	background	background	NOUN
fnp-6108	67	189	:	:	PUNCT
fnp-6108	67	190	the	the	DET
fnp-6108	67	191	gut	gut	NOUN
fnp-6108	67	192	microbiome	microbiome	NOUN
fnp-6108	67	193	is	be	AUX
fnp-6108	67	194	a	a	DET
fnp-6108	67	195	complex	complex	ADJ
fnp-6108	67	196	system	system	NOUN
fnp-6108	67	197	within	within	ADP
fnp-6108	67	198	the	the	DET
fnp-6108	67	199	human	human	ADJ
fnp-6108	67	200	gastrointestinal	gastrointestinal	ADJ
fnp-6108	67	201	tract	tract	NOUN
fnp-6108	67	202	.	.	PUNCT
fnp-6108	68	1	the	the	DET
fnp-6108	68	2	bacteria	bacteria	NOUN
fnp-6108	68	3	play	play	VERB
fnp-6108	68	4	a	a	DET
fnp-6108	68	5	significant	significant	ADJ
fnp-6108	68	6	role	role	NOUN
fnp-6108	68	7	in	in	ADP
fnp-6108	68	8	human	human	ADJ
fnp-6108	68	9	health	health	NOUN
fnp-6108	68	10	,	,	PUNCT
fnp-6108	68	11	and	and	CCONJ
fnp-6108	68	12	some	some	PRON
fnp-6108	68	13	can	can	AUX
fnp-6108	68	14	promote	promote	VERB
fnp-6108	68	15	inflammation	inflammation	NOUN
fnp-6108	68	16	and	and	CCONJ
fnp-6108	68	17	pathologic	pathologic	ADJ
fnp-6108	68	18	processes	process	NOUN
fnp-6108	68	19	through	through	ADP
fnp-6108	68	20	chemical	chemical	ADJ
fnp-6108	68	21	interactions	interaction	NOUN
fnp-6108	68	22	or	or	CCONJ
fnp-6108	68	23	metabolites	metabolite	NOUN
fnp-6108	68	24	.	.	PUNCT
fnp-6108	69	1	gut	gut	VERB
fnp-6108	69	2	microbiome	microbiome	ADJ
fnp-6108	69	3	dysbiosis	dysbiosis	NOUN
fnp-6108	69	4	has	have	AUX
fnp-6108	69	5	been	be	AUX
fnp-6108	69	6	linked	link	VERB
fnp-6108	69	7	to	to	ADP
fnp-6108	69	8	some	some	DET
fnp-6108	69	9	neurological	neurological	ADJ
fnp-6108	69	10	and	and	CCONJ
fnp-6108	69	11	other	other	ADJ
fnp-6108	69	12	diseases	disease	NOUN
fnp-6108	69	13	.	.	PUNCT
fnp-6108	70	1	here	here	ADV
fnp-6108	70	2	we	we	PRON
fnp-6108	70	3	aimed	aim	VERB
fnp-6108	70	4	to	to	PART
fnp-6108	70	5	examine	examine	VERB
fnp-6108	70	6	microbiome	microbiome	ADJ
fnp-6108	70	7	differences	difference	NOUN
fnp-6108	70	8	between	between	ADP
fnp-6108	70	9	patients	patient	NOUN
fnp-6108	70	10	with	with	ADP
fnp-6108	70	11	a	a	DET
fnp-6108	70	12	progressive	progressive	ADJ
fnp-6108	70	13	neurological	neurological	ADJ
fnp-6108	70	14	disorder	disorder	NOUN
fnp-6108	70	15	,	,	PUNCT
fnp-6108	70	16	idiopathic	idiopathic	ADJ
fnp-6108	70	17	normal	normal	ADJ
fnp-6108	70	18	pressure	pressure	NOUN
fnp-6108	70	19	hydrocephalus	hydrocephalus	X
fnp-6108	70	20	(	(	PUNCT
fnp-6108	70	21	inph	inph	PROPN
fnp-6108	70	22	)	)	PUNCT
fnp-6108	70	23	,	,	PUNCT
fnp-6108	70	24	compared	compare	VERB
fnp-6108	70	25	with	with	ADP
fnp-6108	70	26	healthy	healthy	ADJ
fnp-6108	70	27	controls	control	NOUN
fnp-6108	70	28	(	(	PUNCT
fnp-6108	70	29	co	co	NOUN
fnp-6108	70	30	)	)	PUNCT
fnp-6108	70	31	.	.	PUNCT
fnp-6108	71	1	methods	method	NOUN
fnp-6108	71	2	:	:	PUNCT
fnp-6108	71	3	we	we	PRON
fnp-6108	71	4	recruited	recruit	VERB
fnp-6108	71	5	37	37	NUM
fnp-6108	71	6	neurologically	neurologically	ADV
fnp-6108	71	7	healthy	healthy	ADJ
fnp-6108	71	8	co	co	NOUN
fnp-6108	71	9	and	and	CCONJ
fnp-6108	71	10	10	10	NUM
fnp-6108	71	11	patients	patient	NOUN
fnp-6108	71	12	with	with	ADP
fnp-6108	71	13	shunted	shunt	VERB
fnp-6108	71	14	inph	inph	NOUN
fnp-6108	71	15	.	.	PUNCT
fnp-6108	72	1	we	we	PRON
fnp-6108	72	2	evaluated	evaluate	VERB
fnp-6108	72	3	these	these	DET
fnp-6108	72	4	participants	participant	NOUN
fnp-6108	72	5	’	'	PUNCT
fnp-6108	72	6	cognition	cognition	NOUN
fnp-6108	72	7	using	use	VERB
fnp-6108	72	8	the	the	DET
fnp-6108	72	9	cerad	cerad	PROPN
fnp-6108	72	10	-	-	PUNCT
fnp-6108	72	11	nb	nb	PROPN
fnp-6108	72	12	test	test	NOUN
fnp-6108	72	13	battery	battery	NOUN
fnp-6108	72	14	and	and	CCONJ
fnp-6108	72	15	cdr	cdr	PROPN
fnp-6108	72	16	test	test	NOUN
fnp-6108	72	17	,	,	PUNCT
fnp-6108	72	18	and	and	CCONJ
fnp-6108	72	19	collected	collect	VERB
fnp-6108	72	20	a	a	DET
fnp-6108	72	21	variety	variety	NOUN
fnp-6108	72	22	of	of	ADP
fnp-6108	72	23	information	information	NOUN
fnp-6108	72	24	,	,	PUNCT
fnp-6108	72	25	including	include	VERB
fnp-6108	72	26	about	about	ADP
fnp-6108	72	27	dietary	dietary	ADJ
fnp-6108	72	28	habits	habit	NOUN
fnp-6108	72	29	and	and	CCONJ
fnp-6108	72	30	health	health	NOUN
fnp-6108	72	31	.	.	PUNCT
fnp-6108	73	1	we	we	PRON
fnp-6108	73	2	also	also	ADV
fnp-6108	73	3	collected	collect	VERB
fnp-6108	73	4	fecal	fecal	ADJ
fnp-6108	73	5	samples	sample	NOUN
fnp-6108	73	6	,	,	PUNCT
fnp-6108	73	7	which	which	PRON
fnp-6108	73	8	were	be	AUX
fnp-6108	73	9	subjected	subject	VERB
fnp-6108	73	10	to	to	ADP
fnp-6108	73	11	16s	16	NOUN
fnp-6108	73	12	amplicon	amplicon	NOUN
fnp-6108	73	13	sequencing	sequence	VERB
fnp-6108	73	14	to	to	PART
fnp-6108	73	15	analyze	analyze	VERB
fnp-6108	73	16	differences	difference	NOUN
fnp-6108	73	17	in	in	ADP
fnp-6108	73	18	gut	gut	NOUN
fnp-6108	73	19	microbiome	microbiome	NOUN
fnp-6108	73	20	composition	composition	NOUN
fnp-6108	73	21	.	.	PUNCT
fnp-6108	74	1	results	result	NOUN
fnp-6108	74	2	:	:	PUNCT
fnp-6108	74	3	we	we	PRON
fnp-6108	74	4	found	find	VERB
fnp-6108	74	5	that	that	SCONJ
fnp-6108	74	6	the	the	DET
fnp-6108	74	7	inph	inph	PROPN
fnp-6108	74	8	group	group	NOUN
fnp-6108	74	9	exhibited	exhibit	VERB
fnp-6108	74	10	significantly	significantly	ADV
fnp-6108	74	11	different	different	ADJ
fnp-6108	74	12	abundances	abundance	NOUN
fnp-6108	74	13	of	of	ADP
fnp-6108	74	14	10	10	NUM
fnp-6108	74	15	bacterial	bacterial	ADJ
fnp-6108	74	16	genera	genera	NOUN
fnp-6108	74	17	compared	compare	VERB
fnp-6108	74	18	with	with	ADP
fnp-6108	74	19	the	the	DET
fnp-6108	74	20	co	co	NOUN
fnp-6108	74	21	group	group	NOUN
fnp-6108	74	22	.	.	PUNCT
fnp-6108	75	1	the	the	DET
fnp-6108	75	2	escherichia	escherichia	PROPN
fnp-6108	75	3	/	/	SYM
fnp-6108	75	4	shigella	shigella	PROPN
fnp-6108	75	5	and	and	CCONJ
fnp-6108	75	6	anaeromassilibacillus	anaeromassilibacillus	ADJ
fnp-6108	75	7	genera	genera	NOUN
fnp-6108	75	8	were	be	AUX
fnp-6108	75	9	most	most	ADV
fnp-6108	75	10	remarkably	remarkably	ADV
fnp-6108	75	11	increased	increase	VERB
fnp-6108	75	12	.	.	PUNCT
fnp-6108	76	1	other	other	ADJ
fnp-6108	76	2	increased	increase	VERB
fnp-6108	76	3	genera	genera	NOUN
fnp-6108	76	4	were	be	AUX
fnp-6108	76	5	butyrivibrio	butyrivibrio	ADJ
fnp-6108	76	6	,	,	PUNCT
fnp-6108	76	7	duncaniella	duncaniella	NOUN
fnp-6108	76	8	,	,	PUNCT
fnp-6108	76	9	and	and	CCONJ
fnp-6108	76	10	an	an	DET
fnp-6108	76	11	unidentified	unidentified	ADJ
fnp-6108	76	12	genus	genus	NOUN
fnp-6108	76	13	.	.	PUNCT
fnp-6108	77	1	the	the	DET
fnp-6108	77	2	decreased	decrease	VERB
fnp-6108	77	3	genera	genera	NOUN
fnp-6108	77	4	were	be	AUX
fnp-6108	77	5	agathobaculum	agathobaculum	NOUN
fnp-6108	77	6	,	,	PUNCT
fnp-6108	77	7	paramuribaculum	paramuribaculum	NOUN
fnp-6108	77	8	,	,	PUNCT
fnp-6108	77	9	catenibacterium	catenibacterium	NOUN
fnp-6108	77	10	,	,	PUNCT
fnp-6108	77	11	and	and	CCONJ
fnp-6108	77	12	2	2	NUM
fnp-6108	77	13	unidentified	unidentified	ADJ
fnp-6108	77	14	genera	genera	NOUN
fnp-6108	77	15	.	.	PUNCT
fnp-6108	78	1	conclusions	conclusion	NOUN
fnp-6108	78	2	:	:	PUNCT
fnp-6108	78	3	here	here	ADV
fnp-6108	78	4	we	we	PRON
fnp-6108	78	5	report	report	VERB
fnp-6108	78	6	the	the	DET
fnp-6108	78	7	first	first	ADJ
fnp-6108	78	8	identified	identify	VERB
fnp-6108	78	9	microbiome	microbiome	NOUN
fnp-6108	78	10	differences	difference	NOUN
fnp-6108	78	11	in	in	ADP
fnp-6108	78	12	inph	inph	ADJ
fnp-6108	78	13	patients	patient	NOUN
fnp-6108	78	14	compared	compare	VERB
fnp-6108	78	15	with	with	ADP
fnp-6108	78	16	healthy	healthy	ADJ
fnp-6108	78	17	controls	control	NOUN
fnp-6108	78	18	.	.	PUNCT
fnp-6108	78	19	  	  	SPACE
fnp-6108	79	1	free	free	ADJ
fnp-6108	79	2	neuropathol	neuropathol	NOUN
fnp-6108	79	3	5:30:11	5:30:11	NUM
fnp-6108	79	4	artificial	artificial	ADJ
fnp-6108	79	5	intelligence	intelligence	NOUN
fnp-6108	79	6	algorithm	algorithm	NOUN
fnp-6108	79	7	for	for	ADP
fnp-6108	79	8	studying	study	VERB
fnp-6108	79	9	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	79	10	in	in	ADP
fnp-6108	79	11	a	a	DET
fnp-6108	79	12	finnish	finnish	ADJ
fnp-6108	79	13	population	population	NOUN
fnp-6108	79	14	-	-	PUNCT
fnp-6108	79	15	based	base	VERB
fnp-6108	79	16	study	study	NOUN
fnp-6108	79	17	of	of	ADP
fnp-6108	79	18	the	the	DET
fnp-6108	79	19	oldest	oldest	ADV
fnp-6108	79	20	-	-	PUNCT
fnp-6108	79	21	old	old	ADJ
fnp-6108	79	22	(	(	PUNCT
fnp-6108	79	23	vantaa85	vantaa85	NOUN
fnp-6108	79	24	+	+	NOUN
fnp-6108	79	25	)	)	PUNCT
fnp-6108	79	26	kia	kia	PROPN
fnp-6108	79	27	colangelo1	colangelo1	PROPN
fnp-6108	79	28	,	,	PUNCT
fnp-6108	79	29	eloise	eloise	PROPN
fnp-6108	79	30	h.	h.	PROPN
fnp-6108	79	31	kok1	kok1	PROPN
fnp-6108	79	32	,	,	PUNCT
fnp-6108	79	33	henri	henri	PROPN
fnp-6108	79	34	puttonen1,2	puttonen1,2	PROPN
fnp-6108	79	35	,	,	PUNCT
fnp-6108	79	36	mikko	mikko	PROPN
fnp-6108	79	37	i.	i.	PROPN
fnp-6108	79	38	mäyränpää1,2	mäyränpää1,2	PROPN
fnp-6108	79	39	,	,	PUNCT
fnp-6108	79	40	olli	olli	PROPN
fnp-6108	79	41	tynninen1,2	tynninen1,2	PROPN
fnp-6108	79	42	,	,	PUNCT
fnp-6108	79	43	tuomo	tuomo	PROPN
fnp-6108	79	44	polvikoski3	polvikoski3	PROPN
fnp-6108	79	45	,	,	PUNCT
fnp-6108	79	46	liisa	liisa	VERB
fnp-6108	79	47	myllykangas1,2	myllykangas1,2	PROPN
fnp-6108	79	48	department	department	NOUN
fnp-6108	79	49	of	of	ADP
fnp-6108	79	50	pathology	pathology	PROPN
fnp-6108	79	51	,	,	PUNCT
fnp-6108	79	52	university	university	PROPN
fnp-6108	79	53	of	of	ADP
fnp-6108	79	54	helsinki	helsinki	PROPN
fnp-6108	79	55	,	,	PUNCT
fnp-6108	79	56	helsinki	helsinki	PROPN
fnp-6108	79	57	,	,	PUNCT
fnp-6108	79	58	finland	finland	PROPN
fnp-6108	79	59	department	department	PROPN
fnp-6108	79	60	of	of	ADP
fnp-6108	79	61	pathology	pathology	PROPN
fnp-6108	79	62	,	,	PUNCT
fnp-6108	79	63	hus	hus	CCONJ
fnp-6108	79	64	diagnostic	diagnostic	ADJ
fnp-6108	79	65	center	center	NOUN
fnp-6108	79	66	,	,	PUNCT
fnp-6108	79	67	helsinki	helsinki	PROPN
fnp-6108	79	68	university	university	PROPN
fnp-6108	79	69	hospital	hospital	NOUN
fnp-6108	79	70	,	,	PUNCT
fnp-6108	79	71	helsinki	helsinki	PROPN
fnp-6108	79	72	,	,	PUNCT
fnp-6108	79	73	finland	finland	PROPN
fnp-6108	79	74	translational	translational	ADJ
fnp-6108	79	75	and	and	CCONJ
fnp-6108	79	76	clinical	clinical	ADJ
fnp-6108	79	77	research	research	PROPN
fnp-6108	79	78	institute	institute	PROPN
fnp-6108	79	79	,	,	PUNCT
fnp-6108	79	80	newcastle	newcastle	PROPN
fnp-6108	79	81	university	university	PROPN
fnp-6108	79	82	,	,	PUNCT
fnp-6108	79	83	newcastle	newcastle	PROPN
fnp-6108	79	84	upon	upon	SCONJ
fnp-6108	79	85	tyne	tyne	PROPN
fnp-6108	79	86	,	,	PUNCT
fnp-6108	79	87	united	united	PROPN
fnp-6108	79	88	kingdom	kingdom	PROPN
fnp-6108	79	89	brain	brain	NOUN
fnp-6108	79	90	arteriolosclerosis	arteriolosclerosis	PROPN
fnp-6108	79	91	,	,	PUNCT
fnp-6108	79	92	marked	mark	VERB
fnp-6108	79	93	by	by	ADP
fnp-6108	79	94	thickening	thickening	NOUN
fnp-6108	79	95	of	of	ADP
fnp-6108	79	96	the	the	DET
fnp-6108	79	97	arteriolar	arteriolar	ADJ
fnp-6108	79	98	walls	wall	NOUN
fnp-6108	79	99	,	,	PUNCT
fnp-6108	79	100	is	be	AUX
fnp-6108	79	101	a	a	DET
fnp-6108	79	102	common	common	ADJ
fnp-6108	79	103	finding	finding	NOUN
fnp-6108	79	104	in	in	ADP
fnp-6108	79	105	autopsies	autopsy	NOUN
fnp-6108	79	106	of	of	ADP
fnp-6108	79	107	elderly	elderly	ADJ
fnp-6108	79	108	individuals	individual	NOUN
fnp-6108	79	109	and	and	CCONJ
fnp-6108	79	110	is	be	AUX
fnp-6108	79	111	known	know	VERB
fnp-6108	79	112	to	to	PART
fnp-6108	79	113	be	be	AUX
fnp-6108	79	114	linked	link	VERB
fnp-6108	79	115	to	to	ADP
fnp-6108	79	116	cognitive	cognitive	ADJ
fnp-6108	79	117	impairment	impairment	NOUN
fnp-6108	79	118	.	.	PUNCT
fnp-6108	80	1	the	the	DET
fnp-6108	80	2	aim	aim	NOUN
fnp-6108	80	3	of	of	ADP
fnp-6108	80	4	this	this	DET
fnp-6108	80	5	study	study	NOUN
fnp-6108	80	6	was	be	AUX
fnp-6108	80	7	to	to	PART
fnp-6108	80	8	create	create	VERB
fnp-6108	80	9	an	an	DET
fnp-6108	80	10	artificial	artificial	ADJ
fnp-6108	80	11	intelligence	intelligence	NOUN
fnp-6108	80	12	algorithm	algorithm	NOUN
fnp-6108	80	13	that	that	PRON
fnp-6108	80	14	measures	measure	VERB
fnp-6108	80	15	the	the	DET
fnp-6108	80	16	arteriolar	arteriolar	ADJ
fnp-6108	80	17	thickness	thickness	NOUN
fnp-6108	80	18	and	and	CCONJ
fnp-6108	80	19	to	to	PART
fnp-6108	80	20	use	use	VERB
fnp-6108	80	21	this	this	DET
fnp-6108	80	22	data	datum	NOUN
fnp-6108	80	23	to	to	PART
fnp-6108	80	24	analyse	analyse	VERB
fnp-6108	80	25	associations	association	NOUN
fnp-6108	80	26	between	between	ADP
fnp-6108	80	27	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	80	28	and	and	CCONJ
fnp-6108	80	29	vascular	vascular	ADJ
fnp-6108	80	30	risk	risk	NOUN
fnp-6108	80	31	factors	factor	NOUN
fnp-6108	80	32	,	,	PUNCT
fnp-6108	80	33	cognition	cognition	NOUN
fnp-6108	80	34	parameters	parameter	NOUN
fnp-6108	80	35	,	,	PUNCT
fnp-6108	80	36	and	and	CCONJ
fnp-6108	80	37	other	other	ADJ
fnp-6108	80	38	neuropathologies	neuropathologie	NOUN
fnp-6108	80	39	.	.	PUNCT
fnp-6108	81	1	the	the	DET
fnp-6108	81	2	vantaa	vantaa	ADJ
fnp-6108	81	3	85	85	NUM
fnp-6108	81	4	+	+	NUM
fnp-6108	81	5	study	study	NOUN
fnp-6108	81	6	cohort	cohort	NOUN
fnp-6108	81	7	,	,	PUNCT
fnp-6108	81	8	comprising	comprise	VERB
fnp-6108	81	9	601	601	NUM
fnp-6108	81	10	individuals	individual	NOUN
fnp-6108	81	11	aged	age	VERB
fnp-6108	81	12	>	>	PUNCT
fnp-6108	81	13	 	 	SPACE
fnp-6108	81	14	85	85	NUM
fnp-6108	81	15	years	year	NOUN
fnp-6108	81	16	residing	reside	VERB
fnp-6108	81	17	in	in	ADP
fnp-6108	81	18	vantaa	vantaa	PROPN
fnp-6108	81	19	,	,	PUNCT
fnp-6108	81	20	finland	finland	PROPN
fnp-6108	81	21	in	in	ADP
fnp-6108	81	22	1991	1991	NUM
fnp-6108	81	23	,	,	PUNCT
fnp-6108	81	24	forms	form	VERB
fnp-6108	81	25	the	the	DET
fnp-6108	81	26	basis	basis	NOUN
fnp-6108	81	27	of	of	ADP
fnp-6108	81	28	our	our	PRON
fnp-6108	81	29	study	study	NOUN
fnp-6108	81	30	.	.	PUNCT
fnp-6108	82	1	hematoxylin	hematoxylin	PROPN
fnp-6108	82	2	and	and	CCONJ
fnp-6108	82	3	eosin	eosin	NOUN
fnp-6108	82	4	(	(	PUNCT
fnp-6108	82	5	he	he	PRON
fnp-6108	82	6	)	)	PUNCT
fnp-6108	82	7	staining	stain	VERB
fnp-6108	82	8	of	of	ADP
fnp-6108	82	9	amygdala	amygdala	NOUN
fnp-6108	82	10	,	,	PUNCT
fnp-6108	82	11	hippocampus	hippocampus	NOUN
fnp-6108	82	12	and	and	CCONJ
fnp-6108	82	13	frontal	frontal	ADJ
fnp-6108	82	14	white	white	ADJ
fnp-6108	82	15	matter	matter	NOUN
fnp-6108	82	16	tissue	tissue	NOUN
fnp-6108	82	17	samples	sample	NOUN
fnp-6108	82	18	were	be	AUX
fnp-6108	82	19	used	use	VERB
fnp-6108	82	20	for	for	ADP
fnp-6108	82	21	the	the	DET
fnp-6108	82	22	analysis	analysis	NOUN
fnp-6108	82	23	.	.	PUNCT
fnp-6108	83	1	aiforia	aiforia	ADJ
fnp-6108	83	2	algorithms	algorithm	NOUN
fnp-6108	83	3	were	be	AUX
fnp-6108	83	4	used	use	VERB
fnp-6108	83	5	to	to	PART
fnp-6108	83	6	detect	detect	VERB
fnp-6108	83	7	vessels	vessel	NOUN
fnp-6108	83	8	and	and	CCONJ
fnp-6108	83	9	to	to	PART
fnp-6108	83	10	acquire	acquire	VERB
fnp-6108	83	11	sclerotic	sclerotic	ADJ
fnp-6108	83	12	indexes	index	NOUN
fnp-6108	83	13	(	(	PUNCT
fnp-6108	83	14	si	si	NOUN
fnp-6108	83	15	)	)	PUNCT
fnp-6108	83	16	from	from	ADP
fnp-6108	83	17	each	each	DET
fnp-6108	83	18	brain	brain	NOUN
fnp-6108	83	19	region	region	NOUN
fnp-6108	83	20	.	.	PUNCT
fnp-6108	84	1	cognitive	cognitive	ADJ
fnp-6108	84	2	parameters	parameter	NOUN
fnp-6108	84	3	and	and	CCONJ
fnp-6108	84	4	other	other	ADJ
fnp-6108	84	5	neuropathologies	neuropathologie	NOUN
fnp-6108	84	6	have	have	AUX
fnp-6108	84	7	been	be	AUX
fnp-6108	84	8	assessed	assess	VERB
fnp-6108	84	9	in	in	ADP
fnp-6108	84	10	previous	previous	ADJ
fnp-6108	84	11	studies	study	NOUN
fnp-6108	84	12	.	.	PUNCT
fnp-6108	85	1	all	all	DET
fnp-6108	85	2	three	three	NUM
fnp-6108	85	3	brain	brain	NOUN
fnp-6108	85	4	areas	area	NOUN
fnp-6108	85	5	were	be	AUX
fnp-6108	85	6	found	find	VERB
fnp-6108	85	7	to	to	PART
fnp-6108	85	8	have	have	VERB
fnp-6108	85	9	borderline	borderline	NOUN
fnp-6108	85	10	moderate	moderate	ADJ
fnp-6108	85	11	to	to	ADP
fnp-6108	85	12	severe	severe	ADJ
fnp-6108	85	13	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	85	14	according	accord	VERB
fnp-6108	85	15	to	to	ADP
fnp-6108	85	16	si	si	PROPN
fnp-6108	85	17	values	value	NOUN
fnp-6108	85	18	.	.	PUNCT
fnp-6108	86	1	we	we	PRON
fnp-6108	86	2	could	could	AUX
fnp-6108	86	3	not	not	PART
fnp-6108	86	4	find	find	VERB
fnp-6108	86	5	strong	strong	ADJ
fnp-6108	86	6	associations	association	NOUN
fnp-6108	86	7	between	between	ADP
fnp-6108	86	8	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	86	9	and	and	CCONJ
fnp-6108	86	10	known	know	VERB
fnp-6108	86	11	vascular	vascular	ADJ
fnp-6108	86	12	risk	risk	NOUN
fnp-6108	86	13	factors	factor	NOUN
fnp-6108	86	14	,	,	PUNCT
fnp-6108	86	15	such	such	ADJ
fnp-6108	86	16	as	as	ADP
fnp-6108	86	17	hypertension	hypertension	NOUN
fnp-6108	86	18	,	,	PUNCT
fnp-6108	86	19	diabetes	diabetes	NOUN
fnp-6108	86	20	and	and	CCONJ
fnp-6108	86	21	cholesterol	cholesterol	NOUN
fnp-6108	86	22	levels	level	NOUN
fnp-6108	86	23	.	.	PUNCT
fnp-6108	87	1	however	however	ADV
fnp-6108	87	2	,	,	PUNCT
fnp-6108	87	3	we	we	PRON
fnp-6108	87	4	found	find	VERB
fnp-6108	87	5	significant	significant	ADJ
fnp-6108	87	6	associations	association	NOUN
fnp-6108	87	7	between	between	ADP
fnp-6108	87	8	cognitive	cognitive	ADJ
fnp-6108	87	9	parameters	parameter	NOUN
fnp-6108	87	10	(	(	PUNCT
fnp-6108	87	11	dementia	dementia	NOUN
fnp-6108	87	12	and	and	CCONJ
fnp-6108	87	13	mmse	mmse	ADJ
fnp-6108	87	14	scores	score	NOUN
fnp-6108	87	15	)	)	PUNCT
fnp-6108	87	16	and	and	CCONJ
fnp-6108	87	17	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	87	18	in	in	ADP
fnp-6108	87	19	all	all	DET
fnp-6108	87	20	3	3	NUM
fnp-6108	87	21	brain	brain	NOUN
fnp-6108	87	22	areas	area	NOUN
fnp-6108	87	23	.	.	PUNCT
fnp-6108	88	1	furthermore	furthermore	ADV
fnp-6108	88	2	,	,	PUNCT
fnp-6108	88	3	adnc	adnc	ADJ
fnp-6108	88	4	,	,	PUNCT
fnp-6108	88	5	late	late	PROPN
fnp-6108	88	6	-	-	PUNCT
fnp-6108	88	7	nc	nc	PROPN
fnp-6108	88	8	and	and	CCONJ
fnp-6108	88	9	small	small	ADJ
fnp-6108	88	10	brain	brain	NOUN
fnp-6108	88	11	infarcts	infarct	NOUN
fnp-6108	88	12	were	be	AUX
fnp-6108	88	13	significantly	significantly	ADV
fnp-6108	88	14	associated	associate	VERB
fnp-6108	88	15	with	with	ADP
fnp-6108	88	16	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	88	17	in	in	ADP
fnp-6108	88	18	amygdala	amygdala	NOUN
fnp-6108	88	19	and	and	CCONJ
fnp-6108	88	20	frontal	frontal	ADJ
fnp-6108	88	21	white	white	ADJ
fnp-6108	88	22	matter	matter	NOUN
fnp-6108	88	23	.	.	PUNCT
fnp-6108	89	1	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	89	2	may	may	AUX
fnp-6108	89	3	be	be	AUX
fnp-6108	89	4	involved	involve	VERB
fnp-6108	89	5	in	in	ADP
fnp-6108	89	6	the	the	DET
fnp-6108	89	7	pathogenesis	pathogenesis	NOUN
fnp-6108	89	8	of	of	ADP
fnp-6108	89	9	dementia	dementia	PROPN
fnp-6108	89	10	,	,	PUNCT
fnp-6108	89	11	alzheimer	alzheimer	PROPN
fnp-6108	89	12	’s	’s	PART
fnp-6108	89	13	disease	disease	NOUN
fnp-6108	89	14	and	and	CCONJ
fnp-6108	89	15	late	late	PROPN
fnp-6108	89	16	-	-	PUNCT
fnp-6108	89	17	nc	nc	PROPN
fnp-6108	89	18	.	.	PROPN
fnp-6108	89	19	vascular	vascular	ADJ
fnp-6108	89	20	risk	risk	NOUN
fnp-6108	89	21	factors	factor	NOUN
fnp-6108	89	22	for	for	ADP
fnp-6108	89	23	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	89	24	may	may	AUX
fnp-6108	89	25	be	be	AUX
fnp-6108	89	26	different	different	ADJ
fnp-6108	89	27	from	from	ADP
fnp-6108	89	28	those	those	PRON
fnp-6108	89	29	of	of	ADP
fnp-6108	89	30	large	large	ADJ
fnp-6108	89	31	vessel	vessel	NOUN
fnp-6108	89	32	atherosclerosis	atherosclerosis	NOUN
fnp-6108	89	33	in	in	ADP
fnp-6108	89	34	the	the	DET
fnp-6108	89	35	very	very	ADV
fnp-6108	89	36	elderly	elderly	ADJ
fnp-6108	89	37	age	age	NOUN
fnp-6108	89	38	group	group	NOUN
fnp-6108	89	39	.	.	PUNCT
fnp-6108	89	40	  	  	SPACE
fnp-6108	90	1	free	free	ADJ
fnp-6108	90	2	neuropathol	neuropathol	NOUN
fnp-6108	90	3	5:30:12	5:30:12	NUM
fnp-6108	90	4	microvascular	microvascular	ADJ
fnp-6108	90	5	brain	brain	NOUN
fnp-6108	90	6	raspberries	raspberry	NOUN
fnp-6108	90	7	:	:	PUNCT
fnp-6108	90	8	a	a	DET
fnp-6108	90	9	clinicopathological	clinicopathological	ADJ
fnp-6108	90	10	study	study	NOUN
fnp-6108	90	11	henric	henric	NOUN
fnp-6108	90	12	ek	ek	PROPN
fnp-6108	90	13	olofsson1	olofsson1	PROPN
fnp-6108	90	14	,	,	PUNCT
fnp-6108	90	15	elisabet	elisabet	ADJ
fnp-6108	90	16	englund1	englund1	PROPN
fnp-6108	90	17	division	division	NOUN
fnp-6108	90	18	of	of	ADP
fnp-6108	90	19	pathology	pathology	PROPN
fnp-6108	90	20	,	,	PUNCT
fnp-6108	90	21	clinical	clinical	PROPN
fnp-6108	90	22	sciences	sciences	PROPN
fnp-6108	90	23	lund	lund	PROPN
fnp-6108	90	24	,	,	PUNCT
fnp-6108	90	25	lund	lund	PROPN
fnp-6108	90	26	university	university	PROPN
fnp-6108	90	27	,	,	PUNCT
fnp-6108	90	28	lund	lund	PROPN
fnp-6108	90	29	,	,	PUNCT
fnp-6108	90	30	sweden	sweden	PROPN
fnp-6108	90	31	objectives	objective	NOUN
fnp-6108	90	32	:	:	PUNCT
fnp-6108	90	33	a	a	DET
fnp-6108	90	34	raspberry	raspberry	NOUN
fnp-6108	90	35	is	be	AUX
fnp-6108	90	36	a	a	DET
fnp-6108	90	37	microvascular	microvascular	ADJ
fnp-6108	90	38	formation	formation	NOUN
fnp-6108	90	39	of	of	ADP
fnp-6108	90	40	the	the	DET
fnp-6108	90	41	human	human	ADJ
fnp-6108	90	42	brain	brain	NOUN
fnp-6108	90	43	,	,	PUNCT
fnp-6108	90	44	defined	define	VERB
fnp-6108	90	45	histopathologically	histopathologically	ADV
fnp-6108	90	46	as	as	SCONJ
fnp-6108	90	47	three	three	NUM
fnp-6108	90	48	or	or	CCONJ
fnp-6108	90	49	more	more	ADV
fnp-6108	90	50	transversally	transversally	ADV
fnp-6108	90	51	sectioned	section	VERB
fnp-6108	90	52	vascular	vascular	ADJ
fnp-6108	90	53	lumen	luman	NOUN
fnp-6108	90	54	within	within	ADP
fnp-6108	90	55	a	a	DET
fnp-6108	90	56	common	common	ADJ
fnp-6108	90	57	perivascular	perivascular	ADJ
fnp-6108	90	58	space	space	NOUN
fnp-6108	90	59	.	.	PUNCT
fnp-6108	91	1	the	the	DET
fnp-6108	91	2	aim	aim	NOUN
fnp-6108	91	3	of	of	ADP
fnp-6108	91	4	this	this	DET
fnp-6108	91	5	project	project	NOUN
fnp-6108	91	6	is	be	AUX
fnp-6108	91	7	to	to	PART
fnp-6108	91	8	specify	specify	VERB
fnp-6108	91	9	the	the	DET
fnp-6108	91	10	clinicopathological	clinicopathological	ADJ
fnp-6108	91	11	context	context	NOUN
fnp-6108	91	12	wherein	wherein	ADJ
fnp-6108	91	13	raspberries	raspberry	NOUN
fnp-6108	91	14	occur	occur	VERB
fnp-6108	91	15	.	.	PUNCT
fnp-6108	92	1	a	a	DET
fnp-6108	92	2	hypothesis	hypothesis	NOUN
fnp-6108	92	3	that	that	PRON
fnp-6108	92	4	has	have	AUX
fnp-6108	92	5	guided	guide	VERB
fnp-6108	92	6	our	our	PRON
fnp-6108	92	7	study	study	NOUN
fnp-6108	92	8	designs	design	NOUN
fnp-6108	92	9	is	be	AUX
fnp-6108	92	10	that	that	SCONJ
fnp-6108	92	11	raspberries	raspberry	NOUN
fnp-6108	92	12	form	form	VERB
fnp-6108	92	13	in	in	ADP
fnp-6108	92	14	a	a	DET
fnp-6108	92	15	setting	setting	NOUN
fnp-6108	92	16	of	of	ADP
fnp-6108	92	17	chronically	chronically	ADV
fnp-6108	92	18	recurrent	recurrent	ADJ
fnp-6108	92	19	hypoperfusion	hypoperfusion	NOUN
fnp-6108	92	20	.	.	PUNCT
fnp-6108	93	1	materials	material	NOUN
fnp-6108	93	2	and	and	CCONJ
fnp-6108	93	3	methods	method	NOUN
fnp-6108	93	4	:	:	PUNCT
fnp-6108	93	5	this	this	PRON
fnp-6108	93	6	is	be	AUX
fnp-6108	93	7	a	a	DET
fnp-6108	93	8	retrospective	retrospective	ADJ
fnp-6108	93	9	project	project	NOUN
fnp-6108	93	10	based	base	VERB
fnp-6108	93	11	on	on	ADP
fnp-6108	93	12	archival	archival	NOUN
fnp-6108	93	13	brain	brain	NOUN
fnp-6108	93	14	tissue	tissue	NOUN
fnp-6108	93	15	.	.	PUNCT
fnp-6108	94	1	the	the	DET
fnp-6108	94	2	raspberries	raspberry	NOUN
fnp-6108	94	3	are	be	AUX
fnp-6108	94	4	quantified	quantify	VERB
fnp-6108	94	5	manually	manually	ADV
fnp-6108	94	6	in	in	ADP
fnp-6108	94	7	haematoxylin	haematoxylin	NOUN
fnp-6108	94	8	and	and	CCONJ
fnp-6108	94	9	eosin	eosin	NOUN
fnp-6108	94	10	-	-	PUNCT
fnp-6108	94	11	stained	stain	VERB
fnp-6108	94	12	tissue	tissue	NOUN
fnp-6108	94	13	sections	section	NOUN
fnp-6108	94	14	from	from	ADP
fnp-6108	94	15	the	the	DET
fnp-6108	94	16	cerebral	cerebral	ADJ
fnp-6108	94	17	cortex	cortex	NOUN
fnp-6108	94	18	(	(	PUNCT
fnp-6108	94	19	mainly	mainly	ADV
fnp-6108	94	20	the	the	DET
fnp-6108	94	21	frontal	frontal	ADJ
fnp-6108	94	22	cortex	cortex	NOUN
fnp-6108	94	23	,	,	PUNCT
fnp-6108	94	24	since	since	SCONJ
fnp-6108	94	25	raspberries	raspberry	NOUN
fnp-6108	94	26	have	have	AUX
fnp-6108	94	27	been	be	AUX
fnp-6108	94	28	encountered	encounter	VERB
fnp-6108	94	29	frequently	frequently	ADV
fnp-6108	94	30	in	in	ADP
fnp-6108	94	31	this	this	DET
fnp-6108	94	32	region	region	NOUN
fnp-6108	94	33	)	)	PUNCT
fnp-6108	94	34	.	.	PUNCT
fnp-6108	95	1	we	we	PRON
fnp-6108	95	2	have	have	AUX
fnp-6108	95	3	examined	examine	VERB
fnp-6108	95	4	whether	whether	SCONJ
fnp-6108	95	5	the	the	DET
fnp-6108	95	6	raspberry	raspberry	NOUN
fnp-6108	95	7	density	density	NOUN
fnp-6108	95	8	varies	vary	VERB
fnp-6108	95	9	in	in	ADP
fnp-6108	95	10	relation	relation	NOUN
fnp-6108	95	11	to	to	ADP
fnp-6108	95	12	age	age	NOUN
fnp-6108	95	13	,	,	PUNCT
fnp-6108	95	14	large	large	ADJ
fnp-6108	95	15	vessel	vessel	NOUN
fnp-6108	95	16	disease	disease	NOUN
fnp-6108	95	17	,	,	PUNCT
fnp-6108	95	18	small	small	ADJ
fnp-6108	95	19	vessel	vessel	NOUN
fnp-6108	95	20	disease	disease	NOUN
fnp-6108	95	21	,	,	PUNCT
fnp-6108	95	22	vascular	vascular	ADJ
fnp-6108	95	23	brain	brain	NOUN
fnp-6108	95	24	injury	injury	NOUN
fnp-6108	95	25	,	,	PUNCT
fnp-6108	95	26	vascular	vascular	ADJ
fnp-6108	95	27	dementia	dementia	NOUN
fnp-6108	95	28	,	,	PUNCT
fnp-6108	95	29	neurodegenerative	neurodegenerative	ADJ
fnp-6108	95	30	disease	disease	NOUN
fnp-6108	95	31	,	,	PUNCT
fnp-6108	95	32	hypertension	hypertension	NOUN
fnp-6108	95	33	,	,	PUNCT
fnp-6108	95	34	and	and	CCONJ
fnp-6108	95	35	diabetes	diabetes	NOUN
fnp-6108	95	36	mellitus	mellitus	NOUN
fnp-6108	95	37	.	.	PUNCT
fnp-6108	96	1	results	result	NOUN
fnp-6108	96	2	:	:	PUNCT
fnp-6108	96	3	the	the	DET
fnp-6108	96	4	raspberry	raspberry	NOUN
fnp-6108	96	5	density	density	NOUN
fnp-6108	96	6	increases	increase	VERB
fnp-6108	96	7	with	with	ADP
fnp-6108	96	8	advancing	advance	VERB
fnp-6108	96	9	age	age	NOUN
fnp-6108	96	10	,	,	PUNCT
fnp-6108	96	11	independently	independently	ADV
fnp-6108	96	12	of	of	ADP
fnp-6108	96	13	potential	potential	ADJ
fnp-6108	96	14	confounding	confound	VERB
fnp-6108	96	15	factors	factor	NOUN
fnp-6108	96	16	.	.	PUNCT
fnp-6108	97	1	our	our	PRON
fnp-6108	97	2	findings	finding	NOUN
fnp-6108	97	3	further	far	ADV
fnp-6108	97	4	indicate	indicate	VERB
fnp-6108	97	5	an	an	DET
fnp-6108	97	6	increased	increase	VERB
fnp-6108	97	7	raspberry	raspberry	NOUN
fnp-6108	97	8	density	density	NOUN
fnp-6108	97	9	in	in	ADP
fnp-6108	97	10	patients	patient	NOUN
fnp-6108	97	11	with	with	ADP
fnp-6108	97	12	cerebral	cerebral	ADJ
fnp-6108	97	13	atherosclerosis	atherosclerosis	NOUN
fnp-6108	97	14	,	,	PUNCT
fnp-6108	97	15	hypertensive	hypertensive	ADJ
fnp-6108	97	16	organ	organ	NOUN
fnp-6108	97	17	damage	damage	NOUN
fnp-6108	97	18	(	(	PUNCT
fnp-6108	97	19	exploratory	exploratory	NOUN
fnp-6108	97	20	)	)	PUNCT
fnp-6108	97	21	,	,	PUNCT
fnp-6108	97	22	and	and	CCONJ
fnp-6108	97	23	vascular	vascular	ADJ
fnp-6108	97	24	dementia	dementia	NOUN
fnp-6108	97	25	.	.	PUNCT
fnp-6108	98	1	the	the	DET
fnp-6108	98	2	raspberry	raspberry	NOUN
fnp-6108	98	3	density	density	NOUN
fnp-6108	98	4	of	of	ADP
fnp-6108	98	5	the	the	DET
fnp-6108	98	6	frontal	frontal	ADJ
fnp-6108	98	7	cortex	cortex	NOUN
fnp-6108	98	8	is	be	AUX
fnp-6108	98	9	increased	increase	VERB
fnp-6108	98	10	in	in	ADP
fnp-6108	98	11	frontotemporal	frontotemporal	ADJ
fnp-6108	98	12	lobar	lobar	ADJ
fnp-6108	98	13	degeneration	degeneration	NOUN
fnp-6108	98	14	,	,	PUNCT
fnp-6108	98	15	but	but	CCONJ
fnp-6108	98	16	not	not	PART
fnp-6108	98	17	in	in	ADP
fnp-6108	98	18	alzheimer	alzheimer	PROPN
fnp-6108	98	19	’s	’s	PART
fnp-6108	98	20	disease	disease	NOUN
fnp-6108	98	21	or	or	CCONJ
fnp-6108	98	22	lewy	lewy	ADJ
fnp-6108	98	23	body	body	NOUN
fnp-6108	98	24	disease	disease	NOUN
fnp-6108	98	25	.	.	PUNCT
fnp-6108	99	1	conclusion	conclusion	NOUN
fnp-6108	99	2	:	:	PUNCT
fnp-6108	99	3	raspberries	raspberry	NOUN
fnp-6108	99	4	are	be	AUX
fnp-6108	99	5	a	a	DET
fnp-6108	99	6	partially	partially	ADV
fnp-6108	99	7	age	age	NOUN
fnp-6108	99	8	-	-	PUNCT
fnp-6108	99	9	related	relate	VERB
fnp-6108	99	10	phenomenon	phenomenon	NOUN
fnp-6108	99	11	that	that	PRON
fnp-6108	99	12	becomes	become	VERB
fnp-6108	99	13	more	more	ADV
fnp-6108	99	14	abundant	abundant	ADJ
fnp-6108	99	15	in	in	ADP
fnp-6108	99	16	a	a	DET
fnp-6108	99	17	setting	setting	NOUN
fnp-6108	99	18	of	of	ADP
fnp-6108	99	19	co	co	VERB
fnp-6108	99	20	-	-	ADJ
fnp-6108	99	21	occurring	occur	VERB
fnp-6108	99	22	vascular	vascular	ADJ
fnp-6108	99	23	disease	disease	NOUN
fnp-6108	99	24	.	.	PUNCT
fnp-6108	100	1	the	the	DET
fnp-6108	100	2	raspberry	raspberry	NOUN
fnp-6108	100	3	density	density	NOUN
fnp-6108	100	4	of	of	ADP
fnp-6108	100	5	the	the	DET
fnp-6108	100	6	frontal	frontal	ADJ
fnp-6108	100	7	cortex	cortex	NOUN
fnp-6108	100	8	is	be	AUX
fnp-6108	100	9	increased	increase	VERB
fnp-6108	100	10	in	in	ADP
fnp-6108	100	11	frontotemporal	frontotemporal	ADJ
fnp-6108	100	12	lobar	lobar	ADJ
fnp-6108	100	13	degeneration	degeneration	NOUN
fnp-6108	100	14	compared	compare	VERB
fnp-6108	100	15	to	to	ADP
fnp-6108	100	16	alzheimer	alzheimer	PROPN
fnp-6108	100	17	’s	’s	PART
fnp-6108	100	18	disease	disease	NOUN
fnp-6108	100	19	and	and	CCONJ
fnp-6108	100	20	lewy	lewy	ADJ
fnp-6108	100	21	body	body	NOUN
fnp-6108	100	22	disease	disease	NOUN
fnp-6108	100	23	.	.	PUNCT
fnp-6108	101	1	these	these	DET
fnp-6108	101	2	findings	finding	NOUN
fnp-6108	101	3	can	can	AUX
fnp-6108	101	4	be	be	AUX
fnp-6108	101	5	applied	apply	VERB
fnp-6108	101	6	to	to	PART
fnp-6108	101	7	direct	direct	VERB
fnp-6108	101	8	the	the	DET
fnp-6108	101	9	focus	focus	NOUN
fnp-6108	101	10	of	of	ADP
fnp-6108	101	11	future	future	ADJ
fnp-6108	101	12	research	research	NOUN
fnp-6108	101	13	on	on	ADP
fnp-6108	101	14	the	the	DET
fnp-6108	101	15	pathogenesis	pathogenesis	NOUN
fnp-6108	101	16	and	and	CCONJ
fnp-6108	101	17	consequences	consequence	NOUN
fnp-6108	101	18	of	of	ADP
fnp-6108	101	19	raspberries	raspberry	NOUN
fnp-6108	101	20	,	,	PUNCT
fnp-6108	101	21	including	include	VERB
fnp-6108	101	22	transcriptomics	transcriptomic	NOUN
fnp-6108	101	23	,	,	PUNCT
fnp-6108	101	24	imaging	imaging	NOUN
fnp-6108	101	25	,	,	PUNCT
fnp-6108	101	26	and	and	CCONJ
fnp-6108	101	27	animal	animal	NOUN
fnp-6108	101	28	models	model	NOUN
fnp-6108	101	29	.	.	PUNCT
fnp-6108	101	30	  	  	SPACE
fnp-6108	102	1	free	free	ADJ
fnp-6108	102	2	neuropathol	neuropathol	NOUN
fnp-6108	102	3	5:30:13	5:30:13	NUM
fnp-6108	102	4	cardiac	cardiac	ADJ
fnp-6108	102	5	alpha	alpha	NOUN
fnp-6108	102	6	-	-	PUNCT
fnp-6108	102	7	synuclein	synuclein	NOUN
fnp-6108	102	8	may	may	AUX
fnp-6108	102	9	promote	promote	VERB
fnp-6108	102	10	sudden	sudden	ADJ
fnp-6108	102	11	cardiac	cardiac	ADJ
fnp-6108	102	12	death	death	NOUN
fnp-6108	102	13	in	in	ADP
fnp-6108	102	14	cases	case	NOUN
fnp-6108	102	15	with	with	ADP
fnp-6108	102	16	lewy	lewy	ADJ
fnp-6108	102	17	body	body	NOUN
fnp-6108	102	18	disease	disease	PROPN
fnp-6108	102	19	elisabet	elisabet	PROPN
fnp-6108	102	20	englund1	englund1	PROPN
fnp-6108	102	21	,	,	PUNCT
fnp-6108	102	22	henric	henric	NOUN
fnp-6108	102	23	ek	ek	PROPN
fnp-6108	102	24	olofsson1	olofsson1	PROPN
fnp-6108	102	25	,	,	PUNCT
fnp-6108	102	26	mattias	mattias	PROPN
fnp-6108	102	27	haglund1	haglund1	PROPN
fnp-6108	102	28	,	,	PUNCT
fnp-6108	102	29	keivan	keivan	PROPN
fnp-6108	102	30	javanshiri1	javanshiri1	PROPN
fnp-6108	102	31	lund	lund	PROPN
fnp-6108	102	32	university	university	PROPN
fnp-6108	102	33	,	,	PUNCT
fnp-6108	102	34	lund	lund	PROPN
fnp-6108	102	35	,	,	PUNCT
fnp-6108	102	36	sweden	sweden	PROPN
fnp-6108	102	37	objectives	objective	NOUN
fnp-6108	102	38	:	:	PUNCT
fnp-6108	102	39	the	the	DET
fnp-6108	102	40	hallmark	hallmark	ADJ
fnp-6108	102	41	pathology	pathology	NOUN
fnp-6108	102	42	in	in	ADP
fnp-6108	102	43	lewy	lewy	PROPN
fnp-6108	102	44	body	body	NOUN
fnp-6108	102	45	disease	disease	NOUN
fnp-6108	102	46	(	(	PUNCT
fnp-6108	102	47	lbd	lbd	PROPN
fnp-6108	102	48	)	)	PUNCT
fnp-6108	102	49	is	be	AUX
fnp-6108	102	50	the	the	DET
fnp-6108	102	51	cns	cns	PROPN
fnp-6108	102	52	aggregates	aggregate	NOUN
fnp-6108	102	53	of	of	ADP
fnp-6108	102	54	alpha	alpha	NOUN
fnp-6108	102	55	-	-	PUNCT
fnp-6108	102	56	synuclein	synuclein	NOUN
fnp-6108	102	57	(	(	PUNCT
fnp-6108	102	58	α	α	NOUN
fnp-6108	102	59	-	-	PUNCT
fnp-6108	102	60	syn	syn	NOUN
fnp-6108	102	61	)	)	PUNCT
fnp-6108	102	62	.	.	PUNCT
fnp-6108	103	1	these	these	DET
fnp-6108	103	2	aggregates	aggregate	NOUN
fnp-6108	103	3	are	be	AUX
fnp-6108	103	4	seen	see	VERB
fnp-6108	103	5	in	in	ADP
fnp-6108	103	6	epicardial	epicardial	ADJ
fnp-6108	103	7	nerves	nerve	NOUN
fnp-6108	103	8	,	,	PUNCT
fnp-6108	103	9	in	in	ADP
fnp-6108	103	10	clinical	clinical	ADJ
fnp-6108	103	11	and	and	CCONJ
fnp-6108	103	12	preclinical	preclinical	ADJ
fnp-6108	103	13	stages	stage	NOUN
fnp-6108	103	14	of	of	ADP
fnp-6108	103	15	disease	disease	NOUN
fnp-6108	103	16	(	(	PUNCT
fnp-6108	103	17	1	1	NUM
fnp-6108	103	18	)	)	PUNCT
fnp-6108	103	19	.	.	PUNCT
fnp-6108	104	1	their	their	PRON
fnp-6108	104	2	effects	effect	NOUN
fnp-6108	104	3	on	on	ADP
fnp-6108	104	4	cardiac	cardiac	ADJ
fnp-6108	104	5	function	function	NOUN
fnp-6108	104	6	are	be	AUX
fnp-6108	104	7	not	not	PART
fnp-6108	104	8	fully	fully	ADV
fnp-6108	104	9	known	know	VERB
fnp-6108	104	10	,	,	PUNCT
fnp-6108	104	11	but	but	CCONJ
fnp-6108	104	12	they	they	PRON
fnp-6108	104	13	may	may	AUX
fnp-6108	104	14	trigger	trigger	VERB
fnp-6108	104	15	arrythmia	arrythmia	NOUN
fnp-6108	104	16	and	and	CCONJ
fnp-6108	104	17	cardiac	cardiac	ADJ
fnp-6108	104	18	arrest	arrest	NOUN
fnp-6108	104	19	(	(	PUNCT
fnp-6108	104	20	2	2	NUM
fnp-6108	104	21	)	)	PUNCT
fnp-6108	104	22	.	.	PUNCT
fnp-6108	105	1	our	our	PRON
fnp-6108	105	2	aim	aim	NOUN
fnp-6108	105	3	was	be	AUX
fnp-6108	105	4	to	to	PART
fnp-6108	105	5	investigate	investigate	VERB
fnp-6108	105	6	cause	cause	NOUN
fnp-6108	105	7	of	of	ADP
fnp-6108	105	8	death	death	NOUN
fnp-6108	105	9	and	and	CCONJ
fnp-6108	105	10	prevalence	prevalence	NOUN
fnp-6108	105	11	of	of	ADP
fnp-6108	105	12	cardiovascular	cardiovascular	ADJ
fnp-6108	105	13	disease	disease	NOUN
fnp-6108	105	14	in	in	ADP
fnp-6108	105	15	neuropathologically	neuropathologically	ADV
fnp-6108	105	16	confirmed	confirm	VERB
fnp-6108	105	17	lbd	lbd	PROPN
fnp-6108	105	18	.	.	PROPN
fnp-6108	105	19	method	method	PROPN
fnp-6108	105	20	:	:	PUNCT
fnp-6108	105	21	the	the	DET
fnp-6108	105	22	immediate	immediate	ADJ
fnp-6108	105	23	cause	cause	NOUN
fnp-6108	105	24	of	of	ADP
fnp-6108	105	25	death	death	NOUN
fnp-6108	105	26	was	be	AUX
fnp-6108	105	27	evaluated	evaluate	VERB
fnp-6108	105	28	in	in	ADP
fnp-6108	105	29	78	78	NUM
fnp-6108	105	30	neuropathologically	neuropathologically	ADV
fnp-6108	105	31	confirmed	confirm	VERB
fnp-6108	105	32	cases	case	NOUN
fnp-6108	105	33	of	of	ADP
fnp-6108	105	34	lbd	lbd	PROPN
fnp-6108	105	35	(	(	PUNCT
fnp-6108	105	36	brainstem	brainstem	NOUN
fnp-6108	105	37	,	,	PUNCT
fnp-6108	105	38	limbic	limbic	ADJ
fnp-6108	105	39	or	or	CCONJ
fnp-6108	105	40	cortical	cortical	ADJ
fnp-6108	105	41	)	)	PUNCT
fnp-6108	105	42	.	.	PUNCT
fnp-6108	106	1	all	all	DET
fnp-6108	106	2	cases	case	NOUN
fnp-6108	106	3	exhibited	exhibit	VERB
fnp-6108	106	4	cardiac	cardiac	ADJ
fnp-6108	106	5	α	α	PROPN
fnp-6108	106	6	-	-	PUNCT
fnp-6108	106	7	syn	syn	NOUN
fnp-6108	106	8	.	.	PUNCT
fnp-6108	107	1	cardiovascular	cardiovascular	ADJ
fnp-6108	107	2	data	datum	NOUN
fnp-6108	107	3	(	(	PUNCT
fnp-6108	107	4	i.e.	i.e.	X
fnp-6108	107	5	coronary	coronary	ADJ
fnp-6108	107	6	atherosclerosis	atherosclerosis	NOUN
fnp-6108	107	7	,	,	PUNCT
fnp-6108	107	8	cardiac	cardiac	ADJ
fnp-6108	107	9	hypertrophy	hypertrophy	NOUN
fnp-6108	107	10	,	,	PUNCT
fnp-6108	107	11	myocardial	myocardial	ADJ
fnp-6108	107	12	infarction	infarction	NOUN
fnp-6108	107	13	)	)	PUNCT
fnp-6108	107	14	and	and	CCONJ
fnp-6108	107	15	clinical	clinical	ADJ
fnp-6108	107	16	data	datum	NOUN
fnp-6108	107	17	on	on	ADP
fnp-6108	107	18	cardioand	cardioand	NOUN
fnp-6108	107	19	cerebrovascular	cerebrovascular	ADJ
fnp-6108	107	20	disease	disease	NOUN
fnp-6108	107	21	(	(	PUNCT
fnp-6108	107	22	arrhythmias	arrhythmia	NOUN
fnp-6108	107	23	,	,	PUNCT
fnp-6108	107	24	congestive	congestive	ADJ
fnp-6108	107	25	heart	heart	NOUN
fnp-6108	107	26	failure	failure	NOUN
fnp-6108	107	27	,	,	PUNCT
fnp-6108	107	28	elongated	elongate	VERB
fnp-6108	107	29	qtc	qtc	PROPN
fnp-6108	107	30	,	,	PUNCT
fnp-6108	107	31	stroke	stroke	NOUN
fnp-6108	107	32	)	)	PUNCT
fnp-6108	107	33	,	,	PUNCT
fnp-6108	107	34	and	and	CCONJ
fnp-6108	107	35	risk	risk	NOUN
fnp-6108	107	36	factors	factor	NOUN
fnp-6108	107	37	(	(	PUNCT
fnp-6108	107	38	hypertension	hypertension	NOUN
fnp-6108	107	39	and	and	CCONJ
fnp-6108	107	40	t2	t2	NOUN
fnp-6108	107	41	diabetes	diabetes	NOUN
fnp-6108	107	42	)	)	PUNCT
fnp-6108	107	43	were	be	AUX
fnp-6108	107	44	assessed	assess	VERB
fnp-6108	107	45	.	.	PUNCT
fnp-6108	108	1	controls	control	NOUN
fnp-6108	108	2	were	be	AUX
fnp-6108	108	3	53	53	NUM
fnp-6108	108	4	age	age	NOUN
fnp-6108	108	5	-	-	PUNCT
fnp-6108	108	6	matched	match	VERB
fnp-6108	108	7	subjects	subject	NOUN
fnp-6108	108	8	with	with	ADP
fnp-6108	108	9	other	other	ADJ
fnp-6108	108	10	major	major	ADJ
fnp-6108	108	11	neurocognitive	neurocognitive	ADJ
fnp-6108	108	12	disease	disease	NOUN
fnp-6108	108	13	.	.	PUNCT
fnp-6108	109	1	results	result	NOUN
fnp-6108	109	2	:	:	PUNCT
fnp-6108	109	3	the	the	DET
fnp-6108	109	4	incidence	incidence	NOUN
fnp-6108	109	5	of	of	ADP
fnp-6108	109	6	sudden	sudden	ADJ
fnp-6108	109	7	cardiac	cardiac	ADJ
fnp-6108	109	8	death	death	NOUN
fnp-6108	109	9	was	be	AUX
fnp-6108	109	10	51.3	51.3	NUM
fnp-6108	109	11	 	 	SPACE
fnp-6108	109	12	%	%	NOUN
fnp-6108	109	13	in	in	ADP
fnp-6108	109	14	the	the	DET
fnp-6108	109	15	lbd	lbd	PROPN
fnp-6108	109	16	group	group	PROPN
fnp-6108	109	17	compared	compare	VERB
fnp-6108	109	18	to	to	ADP
fnp-6108	109	19	22.6	22.6	NUM
fnp-6108	109	20	 	 	SPACE
fnp-6108	109	21	%	%	NOUN
fnp-6108	109	22	in	in	ADP
fnp-6108	109	23	the	the	DET
fnp-6108	109	24	control	control	NOUN
fnp-6108	109	25	group	group	NOUN
fnp-6108	109	26	(	(	PUNCT
fnp-6108	109	27	p	p	X
fnp-6108	109	28	 	 	SPACE
fnp-6108	109	29	<	<	X
fnp-6108	109	30	 	 	SPACE
fnp-6108	109	31	0.001	0.001	NUM
fnp-6108	109	32	)	)	PUNCT
fnp-6108	109	33	.	.	PUNCT
fnp-6108	110	1	these	these	DET
fnp-6108	110	2	cases	case	NOUN
fnp-6108	110	3	had	have	VERB
fnp-6108	110	4	terminal	terminal	ADJ
fnp-6108	110	5	cardiac	cardiac	ADJ
fnp-6108	110	6	failure	failure	NOUN
fnp-6108	110	7	without	without	ADP
fnp-6108	110	8	attributes	attribute	NOUN
fnp-6108	110	9	of	of	ADP
fnp-6108	110	10	ischemic	ischemic	ADJ
fnp-6108	110	11	heart	heart	NOUN
fnp-6108	110	12	disease	disease	NOUN
fnp-6108	110	13	.	.	PUNCT
fnp-6108	111	1	no	no	DET
fnp-6108	111	2	other	other	ADJ
fnp-6108	111	3	differences	difference	NOUN
fnp-6108	111	4	were	be	AUX
fnp-6108	111	5	identified	identify	VERB
fnp-6108	111	6	between	between	ADP
fnp-6108	111	7	the	the	DET
fnp-6108	111	8	groups	group	NOUN
fnp-6108	111	9	regarding	regard	VERB
fnp-6108	111	10	other	other	ADJ
fnp-6108	111	11	autopsy	autopsy	ADJ
fnp-6108	111	12	-	-	PUNCT
fnp-6108	111	13	reported	report	VERB
fnp-6108	111	14	cardiac	cardiac	ADJ
fnp-6108	111	15	findings	finding	NOUN
fnp-6108	111	16	or	or	CCONJ
fnp-6108	111	17	clinical	clinical	ADJ
fnp-6108	111	18	disease	disease	NOUN
fnp-6108	111	19	or	or	CCONJ
fnp-6108	111	20	risk	risk	NOUN
fnp-6108	111	21	factors	factor	NOUN
fnp-6108	111	22	.	.	PUNCT
fnp-6108	112	1	conclusions	conclusion	NOUN
fnp-6108	112	2	:	:	PUNCT
fnp-6108	112	3	sudden	sudden	ADJ
fnp-6108	112	4	cardiac	cardiac	ADJ
fnp-6108	112	5	death	death	NOUN
fnp-6108	112	6	may	may	AUX
fnp-6108	112	7	be	be	AUX
fnp-6108	112	8	the	the	DET
fnp-6108	112	9	leading	lead	VERB
fnp-6108	112	10	cause	cause	NOUN
fnp-6108	112	11	of	of	ADP
fnp-6108	112	12	death	death	NOUN
fnp-6108	112	13	in	in	ADP
fnp-6108	112	14	lbd	lbd	PROPN
fnp-6108	112	15	,	,	PUNCT
fnp-6108	112	16	especially	especially	ADV
fnp-6108	112	17	in	in	ADP
fnp-6108	112	18	the	the	DET
fnp-6108	112	19	early	early	ADJ
fnp-6108	112	20	phase	phase	NOUN
fnp-6108	112	21	,	,	PUNCT
fnp-6108	112	22	before	before	ADP
fnp-6108	112	23	clinically	clinically	ADV
fnp-6108	112	24	obvious	obvious	ADJ
fnp-6108	112	25	neurological	neurological	ADJ
fnp-6108	112	26	disease	disease	NOUN
fnp-6108	112	27	.	.	PUNCT
fnp-6108	113	1	there	there	PRON
fnp-6108	113	2	are	be	VERB
fnp-6108	113	3	possibly	possibly	ADV
fnp-6108	113	4	lethal	lethal	ADJ
fnp-6108	113	5	alterations	alteration	NOUN
fnp-6108	113	6	in	in	ADP
fnp-6108	113	7	cardiac	cardiac	ADJ
fnp-6108	113	8	function	function	NOUN
fnp-6108	113	9	caused	cause	VERB
fnp-6108	113	10	by	by	ADP
fnp-6108	113	11	α	α	NOUN
fnp-6108	113	12	-	-	PUNCT
fnp-6108	113	13	synuclein	synuclein	NOUN
fnp-6108	113	14	aggregates	aggregate	NOUN
fnp-6108	113	15	.	.	PUNCT
fnp-6108	114	1	references	reference	NOUN
fnp-6108	114	2	:	:	PUNCT
fnp-6108	114	3	1	1	NUM
fnp-6108	114	4	.	.	PUNCT
fnp-6108	114	5	 	 	SPACE
fnp-6108	115	1	javanshiri	javanshiri	PROPN
fnp-6108	115	2	k	k	PROPN
fnp-6108	115	3	et	et	PROPN
fnp-6108	115	4	al	al	PROPN
fnp-6108	115	5	.	.	PUNCT
fnp-6108	116	1	j	j	PROPN
fnp-6108	116	2	park	park	PROPN
fnp-6108	116	3	dis	dis	PROPN
fnp-6108	116	4	2022;12:1125	2022;12:1125	PROPN
fnp-6108	116	5	-	-	SYM
fnp-6108	116	6	1131	1131	NUM
fnp-6108	116	7	.	.	PUNCT
fnp-6108	117	1	https://doi.org/10.3233/jpd-223161	https://doi.org/10.3233/jpd-223161	NUM
fnp-6108	117	2	2	2	NUM
fnp-6108	117	3	.	.	PUNCT
fnp-6108	117	4	 	 	SPACE
fnp-6108	118	1	javanshiri	javanshiri	PROPN
fnp-6108	118	2	k	k	PROPN
fnp-6108	118	3	et	et	PROPN
fnp-6108	118	4	al	al	PROPN
fnp-6108	118	5	.	.	PROPN
fnp-6108	118	6	jnen	jnen	PROPN
fnp-6108	118	7	2023	2023	NUM
fnp-6108	118	8	feb	feb	PROPN
fnp-6108	118	9	21;82(3):242	21;82(3):242	PROPN
fnp-6108	118	10	-	-	SYM
fnp-6108	118	11	249	249	NUM
fnp-6108	118	12	.	.	PUNCT
fnp-6108	119	1	https://doi.org/10.1093/jnen/nlad001	https://doi.org/10.1093/jnen/nlad001	NOUN
fnp-6108	119	2	  	  	SPACE
fnp-6108	119	3	free	free	ADJ
fnp-6108	119	4	neuropathol	neuropathol	NOUN
fnp-6108	119	5	5:30:14	5:30:14	NUM
fnp-6108	119	6	ageing	age	VERB
fnp-6108	119	7	-	-	PUNCT
fnp-6108	119	8	related	relate	VERB
fnp-6108	119	9	tau	tau	NOUN
fnp-6108	119	10	astrogliopathy	astrogliopathy	ADJ
fnp-6108	119	11	in	in	ADP
fnp-6108	119	12	the	the	DET
fnp-6108	119	13	oldest	old	ADJ
fnp-6108	119	14	old	old	ADJ
fnp-6108	119	15	population	population	NOUN
fnp-6108	119	16	(	(	PUNCT
fnp-6108	119	17	vantaa	vantaa	NOUN
fnp-6108	119	18	85	85	NUM
fnp-6108	119	19	+	+	NUM
fnp-6108	119	20	)	)	PUNCT
fnp-6108	119	21	benjamin	benjamin	PROPN
fnp-6108	119	22	englert1	englert1	PROPN
fnp-6108	119	23	,	,	PUNCT
fnp-6108	119	24	sara	sara	PROPN
fnp-6108	119	25	savola1	savola1	PROPN
fnp-6108	119	26	,	,	PUNCT
fnp-6108	119	27	kia	kia	PROPN
fnp-6108	119	28	colangelo1	colangelo1	PROPN
fnp-6108	119	29	,	,	PUNCT
fnp-6108	119	30	tuomo	tuomo	ADJ
fnp-6108	119	31	polvikoski2	polvikoski2	NOUN
fnp-6108	119	32	,	,	PUNCT
fnp-6108	119	33	liisa	liisa	VERB
fnp-6108	119	34	myllykangas1	myllykangas1	PROPN
fnp-6108	119	35	hus	hus	PROPN
fnp-6108	119	36	helsinki	helsinki	PROPN
fnp-6108	119	37	university	university	PROPN
fnp-6108	119	38	hospital	hospital	NOUN
fnp-6108	119	39	,	,	PUNCT
fnp-6108	119	40	helsinki	helsinki	PROPN
fnp-6108	119	41	,	,	PUNCT
fnp-6108	119	42	finland	finland	PROPN
fnp-6108	119	43	translational	translational	ADJ
fnp-6108	119	44	and	and	CCONJ
fnp-6108	119	45	clinical	clinical	ADJ
fnp-6108	119	46	research	research	PROPN
fnp-6108	119	47	institute	institute	PROPN
fnp-6108	119	48	,	,	PUNCT
fnp-6108	119	49	newcastle	newcastle	PROPN
fnp-6108	119	50	university	university	PROPN
fnp-6108	119	51	,	,	PUNCT
fnp-6108	119	52	newcastle	newcastle	PROPN
fnp-6108	119	53	upon	upon	SCONJ
fnp-6108	119	54	tyne	tyne	PROPN
fnp-6108	119	55	,	,	PUNCT
fnp-6108	119	56	united	united	ADJ
fnp-6108	119	57	kingdom	kingdom	PROPN
fnp-6108	119	58	objectives	objective	NOUN
fnp-6108	119	59	:	:	PUNCT
fnp-6108	119	60	ageing	age	VERB
fnp-6108	119	61	-	-	PUNCT
fnp-6108	119	62	related	relate	VERB
fnp-6108	119	63	tau	tau	PROPN
fnp-6108	119	64	astrogliopathy	astrogliopathy	ADJ
fnp-6108	119	65	(	(	PUNCT
fnp-6108	119	66	artag	artag	ADJ
fnp-6108	119	67	)	)	PUNCT
fnp-6108	119	68	,	,	PUNCT
fnp-6108	119	69	the	the	DET
fnp-6108	119	70	occurrence	occurrence	NOUN
fnp-6108	119	71	of	of	ADP
fnp-6108	119	72	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-6108	119	73	tau	tau	PROPN
fnp-6108	119	74	in	in	ADP
fnp-6108	119	75	astrocytes	astrocyte	NOUN
fnp-6108	119	76	,	,	PUNCT
fnp-6108	119	77	is	be	AUX
fnp-6108	119	78	a	a	DET
fnp-6108	119	79	common	common	ADJ
fnp-6108	119	80	finding	finding	NOUN
fnp-6108	119	81	in	in	ADP
fnp-6108	119	82	the	the	DET
fnp-6108	119	83	ageing	age	VERB
fnp-6108	119	84	brain	brain	NOUN
fnp-6108	119	85	.	.	PUNCT
fnp-6108	120	1	however	however	ADV
fnp-6108	120	2	,	,	PUNCT
fnp-6108	120	3	its	its	PRON
fnp-6108	120	4	clinical	clinical	ADJ
fnp-6108	120	5	significance	significance	NOUN
fnp-6108	120	6	remains	remain	VERB
fnp-6108	120	7	elusive	elusive	ADJ
fnp-6108	120	8	and	and	CCONJ
fnp-6108	120	9	quantitative	quantitative	ADJ
fnp-6108	120	10	studies	study	NOUN
fnp-6108	120	11	are	be	AUX
fnp-6108	120	12	scarce	scarce	ADJ
fnp-6108	120	13	.	.	PUNCT
fnp-6108	121	1	here	here	ADV
fnp-6108	121	2	we	we	PRON
fnp-6108	121	3	assessed	assess	VERB
fnp-6108	121	4	the	the	DET
fnp-6108	121	5	frequency	frequency	NOUN
fnp-6108	121	6	and	and	CCONJ
fnp-6108	121	7	impact	impact	NOUN
fnp-6108	121	8	of	of	ADP
fnp-6108	121	9	artag	artag	NOUN
fnp-6108	121	10	in	in	ADP
fnp-6108	121	11	a	a	DET
fnp-6108	121	12	general	general	ADJ
fnp-6108	121	13	late	late	ADJ
fnp-6108	121	14	-	-	PUNCT
fnp-6108	121	15	life	life	NOUN
fnp-6108	121	16	aged	aged	ADJ
fnp-6108	121	17	population	population	NOUN
fnp-6108	121	18	.	.	PUNCT
fnp-6108	122	1	methods	method	NOUN
fnp-6108	122	2	:	:	PUNCT
fnp-6108	122	3	immunohistochemical	immunohistochemical	ADJ
fnp-6108	122	4	staining	staining	NOUN
fnp-6108	122	5	using	use	VERB
fnp-6108	122	6	at8	at8	PROPN
fnp-6108	122	7	tau	tau	PROPN
fnp-6108	122	8	antibody	antibody	NOUN
fnp-6108	122	9	were	be	AUX
fnp-6108	122	10	carried	carry	VERB
fnp-6108	122	11	out	out	ADP
fnp-6108	122	12	on	on	ADP
fnp-6108	122	13	the	the	DET
fnp-6108	122	14	vantaa	vantaa	ADJ
fnp-6108	122	15	85	85	NUM
fnp-6108	122	16	+	+	NUM
fnp-6108	122	17	study	study	NOUN
fnp-6108	122	18	,	,	PUNCT
fnp-6108	122	19	a	a	DET
fnp-6108	122	20	population	population	NOUN
fnp-6108	122	21	-	-	PUNCT
fnp-6108	122	22	based	base	VERB
fnp-6108	122	23	cohort	cohort	NOUN
fnp-6108	122	24	containing	contain	VERB
fnp-6108	122	25	over	over	ADP
fnp-6108	122	26	300	300	NUM
fnp-6108	122	27	brains	brain	NOUN
fnp-6108	122	28	of	of	ADP
fnp-6108	122	29	subjects	subject	NOUN
fnp-6108	122	30	older	old	ADJ
fnp-6108	122	31	than	than	ADP
fnp-6108	122	32	85	85	NUM
fnp-6108	122	33	years	year	NOUN
fnp-6108	122	34	with	with	ADP
fnp-6108	122	35	various	various	ADJ
fnp-6108	122	36	levels	level	NOUN
fnp-6108	122	37	of	of	ADP
fnp-6108	122	38	cognitive	cognitive	ADJ
fnp-6108	122	39	impairment	impairment	NOUN
fnp-6108	122	40	and	and	CCONJ
fnp-6108	122	41	neurodegenerative	neurodegenerative	ADJ
fnp-6108	122	42	pathologies	pathology	NOUN
fnp-6108	122	43	.	.	PUNCT
fnp-6108	123	1	we	we	PRON
fnp-6108	123	2	assessed	assess	VERB
fnp-6108	123	3	the	the	DET
fnp-6108	123	4	appearance	appearance	NOUN
fnp-6108	123	5	of	of	ADP
fnp-6108	123	6	pathognomonic	pathognomonic	ADJ
fnp-6108	123	7	astrocytic	astrocytic	ADJ
fnp-6108	123	8	tau	tau	PROPN
fnp-6108	123	9	deposits	deposit	NOUN
fnp-6108	123	10	(	(	PUNCT
fnp-6108	123	11	thorny	thorny	ADV
fnp-6108	123	12	-	-	PUNCT
fnp-6108	123	13	shaped	shape	VERB
fnp-6108	123	14	and	and	CCONJ
fnp-6108	123	15	granular	granular	ADJ
fnp-6108	123	16	/	/	SYM
fnp-6108	123	17	fuzzy	fuzzy	ADJ
fnp-6108	123	18	astrocytes	astrocyte	NOUN
fnp-6108	123	19	)	)	PUNCT
fnp-6108	123	20	and	and	CCONJ
fnp-6108	123	21	their	their	PRON
fnp-6108	123	22	regional	regional	ADJ
fnp-6108	123	23	distribution	distribution	NOUN
fnp-6108	123	24	in	in	ADP
fnp-6108	123	25	the	the	DET
fnp-6108	123	26	limbic	limbic	ADJ
fnp-6108	123	27	system	system	NOUN
fnp-6108	123	28	(	(	PUNCT
fnp-6108	123	29	amygdala	amygdala	NOUN
fnp-6108	123	30	and	and	CCONJ
fnp-6108	123	31	hippocampus	hippocampus	NOUN
fnp-6108	123	32	)	)	PUNCT
fnp-6108	123	33	of	of	ADP
fnp-6108	123	34	the	the	DET
fnp-6108	123	35	oldest	old	ADJ
fnp-6108	123	36	old	old	ADJ
fnp-6108	123	37	in	in	ADP
fnp-6108	123	38	a	a	DET
fnp-6108	123	39	quantitative	quantitative	ADJ
fnp-6108	123	40	manner	manner	NOUN
fnp-6108	123	41	using	use	VERB
fnp-6108	123	42	the	the	DET
fnp-6108	123	43	aiforia	aiforia	ADJ
fnp-6108	123	44	digital	digital	ADJ
fnp-6108	123	45	pathology	pathology	NOUN
fnp-6108	123	46	platform	platform	NOUN
fnp-6108	123	47	.	.	PUNCT
fnp-6108	124	1	we	we	PRON
fnp-6108	124	2	further	far	ADV
fnp-6108	124	3	evaluated	evaluate	VERB
fnp-6108	124	4	the	the	DET
fnp-6108	124	5	association	association	NOUN
fnp-6108	124	6	of	of	ADP
fnp-6108	124	7	artag	artag	ADJ
fnp-6108	124	8	with	with	ADP
fnp-6108	124	9	various	various	ADJ
fnp-6108	124	10	comorbid	comorbid	NOUN
fnp-6108	124	11	pathologies	pathology	NOUN
fnp-6108	124	12	(	(	PUNCT
fnp-6108	124	13	alzheimer	alzheimer	PROPN
fnp-6108	124	14	’s	’s	PART
fnp-6108	124	15	disease	disease	NOUN
fnp-6108	124	16	,	,	PUNCT
fnp-6108	124	17	lewy	lewy	PROPN
fnp-6108	124	18	-	-	PUNCT
fnp-6108	124	19	related	relate	VERB
fnp-6108	124	20	pathology	pathology	NOUN
fnp-6108	124	21	,	,	PUNCT
fnp-6108	124	22	late	late	ADJ
fnp-6108	124	23	,	,	PUNCT
fnp-6108	124	24	argyrophilic	argyrophilic	ADJ
fnp-6108	124	25	grains	grain	NOUN
fnp-6108	124	26	,	,	PUNCT
fnp-6108	124	27	vascular	vascular	ADJ
fnp-6108	124	28	alterations	alteration	NOUN
fnp-6108	124	29	,	,	PUNCT
fnp-6108	124	30	and	and	CCONJ
fnp-6108	124	31	hippocampal	hippocampal	ADJ
fnp-6108	124	32	sclerosis	sclerosis	NOUN
fnp-6108	124	33	)	)	PUNCT
fnp-6108	124	34	.	.	PUNCT
fnp-6108	125	1	moreover	moreover	ADV
fnp-6108	125	2	,	,	PUNCT
fnp-6108	125	3	the	the	DET
fnp-6108	125	4	artag	artag	ADJ
fnp-6108	125	5	burden	burden	NOUN
fnp-6108	125	6	was	be	AUX
fnp-6108	125	7	compared	compare	VERB
fnp-6108	125	8	to	to	ADP
fnp-6108	125	9	clinical	clinical	ADJ
fnp-6108	125	10	parameters	parameter	NOUN
fnp-6108	125	11	such	such	ADJ
fnp-6108	125	12	as	as	ADP
fnp-6108	125	13	age	age	NOUN
fnp-6108	125	14	at	at	ADP
fnp-6108	125	15	death	death	NOUN
fnp-6108	125	16	and	and	CCONJ
fnp-6108	125	17	sex	sex	NOUN
fnp-6108	125	18	,	,	PUNCT
fnp-6108	125	19	smoking	smoking	NOUN
fnp-6108	125	20	,	,	PUNCT
fnp-6108	125	21	hypertension	hypertension	NOUN
fnp-6108	125	22	and	and	CCONJ
fnp-6108	125	23	type	type	NOUN
fnp-6108	125	24	2	2	NUM
fnp-6108	125	25	diabetes	diabetes	NOUN
fnp-6108	125	26	mellitus	mellitus	NOUN
fnp-6108	125	27	medication	medication	NOUN
fnp-6108	125	28	,	,	PUNCT
fnp-6108	125	29	blood	blood	NOUN
fnp-6108	125	30	cholesterol	cholesterol	NOUN
fnp-6108	125	31	and	and	CCONJ
fnp-6108	125	32	cognitive	cognitive	ADJ
fnp-6108	125	33	capacity	capacity	NOUN
fnp-6108	125	34	(	(	PUNCT
fnp-6108	125	35	dementia	dementia	NOUN
fnp-6108	125	36	according	accord	VERB
fnp-6108	125	37	to	to	ADP
fnp-6108	125	38	dsm	dsm	PROPN
fnp-6108	125	39	iii	iii	PROPN
fnp-6108	125	40	-	-	PUNCT
fnp-6108	125	41	r	r	NOUN
fnp-6108	125	42	criteria	criterion	NOUN
fnp-6108	125	43	and	and	CCONJ
fnp-6108	125	44	mmse	mmse	ADJ
fnp-6108	125	45	scores	score	NOUN
fnp-6108	125	46	)	)	PUNCT
fnp-6108	125	47	,	,	PUNCT
fnp-6108	125	48	as	as	ADV
fnp-6108	125	49	well	well	ADV
fnp-6108	125	50	as	as	ADP
fnp-6108	125	51	genetic	genetic	ADJ
fnp-6108	125	52	parameters	parameter	NOUN
fnp-6108	125	53	(	(	PUNCT
fnp-6108	125	54	apoe	apoe	NOUN
fnp-6108	125	55	genotype	genotype	NOUN
fnp-6108	125	56	,	,	PUNCT
fnp-6108	125	57	tau	tau	PROPN
fnp-6108	125	58	h1	h1	PROPN
fnp-6108	125	59	/	/	SYM
fnp-6108	125	60	h2	h2	NOUN
fnp-6108	125	61	haplotypes	haplotype	NOUN
fnp-6108	125	62	)	)	PUNCT
fnp-6108	125	63	.	.	PUNCT
fnp-6108	126	1	expected	expect	VERB
fnp-6108	126	2	results	result	NOUN
fnp-6108	126	3	:	:	PUNCT
fnp-6108	126	4	we	we	PRON
fnp-6108	126	5	expect	expect	VERB
fnp-6108	126	6	a	a	DET
fnp-6108	126	7	detailed	detailed	ADJ
fnp-6108	126	8	assessment	assessment	NOUN
fnp-6108	126	9	of	of	ADP
fnp-6108	126	10	artag	artag	ADJ
fnp-6108	126	11	frequency	frequency	NOUN
fnp-6108	126	12	in	in	ADP
fnp-6108	126	13	the	the	DET
fnp-6108	126	14	general	general	ADJ
fnp-6108	126	15	late	late	ADJ
fnp-6108	126	16	-	-	PUNCT
fnp-6108	126	17	life	life	NOUN
fnp-6108	126	18	aged	aged	ADJ
fnp-6108	126	19	population	population	NOUN
fnp-6108	126	20	and	and	CCONJ
fnp-6108	126	21	its	its	PRON
fnp-6108	126	22	association	association	NOUN
fnp-6108	126	23	with	with	ADP
fnp-6108	126	24	various	various	ADJ
fnp-6108	126	25	clinicopathological	clinicopathological	ADJ
fnp-6108	126	26	parameters	parameter	NOUN
fnp-6108	126	27	.	.	PUNCT
fnp-6108	126	28	  	  	SPACE
fnp-6108	127	1	free	free	ADJ
fnp-6108	127	2	neuropathol	neuropathol	NOUN
fnp-6108	127	3	5:30:15	5:30:15	NUM
fnp-6108	127	4	3d	3d	NUM
fnp-6108	127	5	microscopy	microscopy	NOUN
fnp-6108	127	6	unravels	unravel	VERB
fnp-6108	127	7	details	detail	NOUN
fnp-6108	127	8	in	in	ADP
fnp-6108	127	9	amyloid	amyloid	NOUN
fnp-6108	127	10	plaque	plaque	NOUN
fnp-6108	127	11	-	-	PUNCT
fnp-6108	127	12	microglia	microglia	NOUN
fnp-6108	127	13	interaction	interaction	NOUN
fnp-6108	127	14	in	in	ADP
fnp-6108	127	15	app	app	PROPN
fnp-6108	127	16	/	/	SYM
fnp-6108	127	17	ps1	ps1	NOUN
fnp-6108	127	18	mice	mouse	NOUN
fnp-6108	127	19	maria	maria	PROPN
fnp-6108	127	20	gotkiewicz1	gotkiewicz1	PROPN
fnp-6108	127	21	,	,	PUNCT
fnp-6108	127	22	heikki	heikki	PROPN
fnp-6108	127	23	tanila1	tanila1	PROPN
fnp-6108	128	1	university	university	PROPN
fnp-6108	128	2	of	of	ADP
fnp-6108	128	3	eastern	eastern	PROPN
fnp-6108	128	4	finland	finland	PROPN
fnp-6108	128	5	,	,	PUNCT
fnp-6108	128	6	kuopio	kuopio	PROPN
fnp-6108	128	7	,	,	PUNCT
fnp-6108	128	8	finland	finland	PROPN
fnp-6108	128	9	objectives	objective	NOUN
fnp-6108	128	10	:	:	PUNCT
fnp-6108	128	11	microglia	microglia	NOUN
fnp-6108	128	12	clustering	cluster	VERB
fnp-6108	128	13	around	around	ADP
fnp-6108	128	14	amyloid	amyloid	NOUN
fnp-6108	128	15	plaques	plaque	NOUN
fnp-6108	128	16	is	be	AUX
fnp-6108	128	17	well	well	ADV
fnp-6108	128	18	established	establish	VERB
fnp-6108	128	19	but	but	CCONJ
fnp-6108	128	20	how	how	SCONJ
fnp-6108	128	21	their	their	PRON
fnp-6108	128	22	contact	contact	NOUN
fnp-6108	128	23	the	the	DET
fnp-6108	128	24	plaque	plaque	NOUN
fnp-6108	128	25	with	with	ADP
fnp-6108	128	26	their	their	PRON
fnp-6108	128	27	processes	process	NOUN
fnp-6108	128	28	is	be	AUX
fnp-6108	128	29	difficult	difficult	ADJ
fnp-6108	128	30	to	to	PART
fnp-6108	128	31	see	see	VERB
fnp-6108	128	32	in	in	ADP
fnp-6108	128	33	histological	histological	ADJ
fnp-6108	128	34	sections	section	NOUN
fnp-6108	128	35	.	.	PUNCT
fnp-6108	129	1	we	we	PRON
fnp-6108	129	2	aimed	aim	VERB
fnp-6108	129	3	to	to	PART
fnp-6108	129	4	visualize	visualize	VERB
fnp-6108	129	5	details	detail	NOUN
fnp-6108	129	6	of	of	ADP
fnp-6108	129	7	amyloid	amyloid	NOUN
fnp-6108	129	8	plaque	plaque	NOUN
fnp-6108	129	9	-	-	PUNCT
fnp-6108	129	10	microglia	microglia	NOUN
fnp-6108	129	11	interaction	interaction	NOUN
fnp-6108	129	12	in	in	ADP
fnp-6108	129	13	alzheimer	alzheimer	PROPN
fnp-6108	129	14	model	model	NOUN
fnp-6108	129	15	mice	mouse	NOUN
fnp-6108	129	16	at	at	ADP
fnp-6108	129	17	different	different	ADJ
fnp-6108	129	18	stages	stage	NOUN
fnp-6108	129	19	of	of	ADP
fnp-6108	129	20	the	the	DET
fnp-6108	129	21	amyloid	amyloid	NOUN
fnp-6108	129	22	plaque	plaque	NOUN
fnp-6108	129	23	formation	formation	NOUN
fnp-6108	129	24	through	through	ADP
fnp-6108	129	25	a	a	DET
fnp-6108	129	26	3d	3d	NUM
fnp-6108	129	27	imaging	imaging	NOUN
fnp-6108	129	28	approach	approach	NOUN
fnp-6108	129	29	.	.	PUNCT
fnp-6108	130	1	methods	method	NOUN
fnp-6108	130	2	:	:	PUNCT
fnp-6108	130	3	we	we	PRON
fnp-6108	130	4	cross	cross	VERB
fnp-6108	130	5	-	-	ADJ
fnp-6108	130	6	bred	breed	VERB
fnp-6108	130	7	amyloid	amyloid	NOUN
fnp-6108	130	8	plaque	plaque	NOUN
fnp-6108	130	9	forming	form	VERB
fnp-6108	130	10	app	app	ADJ
fnp-6108	130	11	/	/	SYM
fnp-6108	130	12	ps1	ps1	NOUN
fnp-6108	130	13	mice	mouse	NOUN
fnp-6108	130	14	with	with	ADP
fnp-6108	130	15	cxcr1	cxcr1	PROPN
fnp-6108	130	16	-	-	PUNCT
fnp-6108	130	17	gfp	gfp	PROPN
fnp-6108	130	18	mice	mouse	NOUN
fnp-6108	130	19	expressing	express	VERB
fnp-6108	130	20	gfp	gfp	PROPN
fnp-6108	130	21	microglia	microglia	NOUN
fnp-6108	130	22	which	which	PRON
fnp-6108	130	23	were	be	AUX
fnp-6108	130	24	examined	examine	VERB
fnp-6108	130	25	at	at	ADP
fnp-6108	130	26	age	age	NOUN
fnp-6108	130	27	of	of	ADP
fnp-6108	130	28	13	13	NUM
fnp-6108	130	29	months	month	NOUN
fnp-6108	130	30	.	.	PUNCT
fnp-6108	131	1	we	we	PRON
fnp-6108	131	2	took	take	VERB
fnp-6108	131	3	100	100	NUM
fnp-6108	131	4	 	 	SPACE
fnp-6108	131	5	μm	μm	NUM
fnp-6108	131	6	coronal	coronal	ADJ
fnp-6108	131	7	sections	section	NOUN
fnp-6108	131	8	at	at	ADP
fnp-6108	131	9	the	the	DET
fnp-6108	131	10	level	level	NOUN
fnp-6108	131	11	of	of	ADP
fnp-6108	131	12	dentate	dentate	ADJ
fnp-6108	131	13	gyrus	gyrus	NOUN
fnp-6108	131	14	and	and	CCONJ
fnp-6108	131	15	stained	stain	VERB
fnp-6108	131	16	them	they	PRON
fnp-6108	131	17	with	with	ADP
fnp-6108	131	18	antibodies	antibody	NOUN
fnp-6108	131	19	against	against	ADP
fnp-6108	131	20	amyloid	amyloid	NOUN
fnp-6108	131	21	-	-	PUNCT
fnp-6108	131	22	β	β	NOUN
fnp-6108	131	23	,	,	PUNCT
fnp-6108	131	24	galectin-3	galectin-3	PROPN
fnp-6108	131	25	and	and	CCONJ
fnp-6108	131	26	cd68	cd68	PROPN
fnp-6108	131	27	(	(	PUNCT
fnp-6108	131	28	marker	marker	NOUN
fnp-6108	131	29	of	of	ADP
fnp-6108	131	30	phagocytosis	phagocytosis	NOUN
fnp-6108	131	31	)	)	PUNCT
fnp-6108	131	32	protein	protein	NOUN
fnp-6108	131	33	.	.	PUNCT
fnp-6108	132	1	the	the	DET
fnp-6108	132	2	mounting	mount	VERB
fnp-6108	132	3	medium	medium	NOUN
fnp-6108	132	4	contained	contain	VERB
fnp-6108	132	5	dapi	dapi	ADV
fnp-6108	132	6	which	which	PRON
fnp-6108	132	7	besides	besides	SCONJ
fnp-6108	132	8	nuclei	nucleus	NOUN
fnp-6108	132	9	stains	stain	VERB
fnp-6108	132	10	the	the	DET
fnp-6108	132	11	amyloid	amyloid	NOUN
fnp-6108	132	12	plaque	plaque	NOUN
fnp-6108	132	13	core	core	NOUN
fnp-6108	132	14	.	.	PUNCT
fnp-6108	133	1	isolated	isolate	VERB
fnp-6108	133	2	clusters	cluster	NOUN
fnp-6108	133	3	of	of	ADP
fnp-6108	133	4	amyloid	amyloid	NOUN
fnp-6108	133	5	plaque	plaque	NOUN
fnp-6108	133	6	with	with	ADP
fnp-6108	133	7	the	the	DET
fnp-6108	133	8	surrounding	surround	VERB
fnp-6108	133	9	microglia	microglia	NOUN
fnp-6108	133	10	were	be	AUX
fnp-6108	133	11	imaged	image	VERB
fnp-6108	133	12	in	in	ADP
fnp-6108	133	13	a	a	DET
fnp-6108	133	14	35	35	NUM
fnp-6108	133	15	 	 	SPACE
fnp-6108	133	16	μm	μm	NUM
fnp-6108	133	17	stack	stack	NOUN
fnp-6108	133	18	with	with	ADP
fnp-6108	133	19	zeiss	zeiss	PROPN
fnp-6108	133	20	lsm	lsm	PROPN
fnp-6108	133	21	800	800	NUM
fnp-6108	133	22	confocal	confocal	ADJ
fnp-6108	133	23	microscope	microscope	NOUN
fnp-6108	133	24	and	and	CCONJ
fnp-6108	133	25	3d	3d	NUM
fnp-6108	133	26	rendered	render	VERB
fnp-6108	133	27	and	and	CCONJ
fnp-6108	133	28	analysed	analyse	VERB
fnp-6108	133	29	with	with	ADP
fnp-6108	133	30	imarisx64	imarisx64	NOUN
fnp-6108	133	31	10.0.1	10.0.1	NUM
fnp-6108	133	32	results	result	NOUN
fnp-6108	133	33	:	:	PUNCT
fnp-6108	133	34	we	we	PRON
fnp-6108	133	35	imaged	image	VERB
fnp-6108	133	36	61	61	NUM
fnp-6108	133	37	clusters	cluster	NOUN
fnp-6108	133	38	from	from	ADP
fnp-6108	133	39	three	three	NUM
fnp-6108	133	40	mice	mouse	NOUN
fnp-6108	133	41	.	.	PUNCT
fnp-6108	134	1	we	we	PRON
fnp-6108	134	2	observed	observe	VERB
fnp-6108	134	3	that	that	SCONJ
fnp-6108	134	4	microglia	microglia	ADJ
fnp-6108	134	5	processes	process	NOUN
fnp-6108	134	6	were	be	AUX
fnp-6108	134	7	not	not	PART
fnp-6108	134	8	attracted	attract	VERB
fnp-6108	134	9	to	to	PART
fnp-6108	134	10	diffuse	diffuse	VERB
fnp-6108	134	11	amyloid	amyloid	NOUN
fnp-6108	134	12	of	of	ADP
fnp-6108	134	13	the	the	DET
fnp-6108	134	14	plaque	plaque	NOUN
fnp-6108	134	15	shell	shell	NOUN
fnp-6108	134	16	but	but	CCONJ
fnp-6108	134	17	made	make	VERB
fnp-6108	134	18	contacts	contact	NOUN
fnp-6108	134	19	with	with	ADP
fnp-6108	134	20	the	the	DET
fnp-6108	134	21	dense	dense	ADJ
fnp-6108	134	22	dapi+	dapi+	X
fnp-6108	134	23	core	core	NOUN
fnp-6108	134	24	.	.	PUNCT
fnp-6108	135	1	as	as	SCONJ
fnp-6108	135	2	shown	show	VERB
fnp-6108	135	3	earlier	early	ADV
fnp-6108	135	4	,	,	PUNCT
fnp-6108	135	5	homeostatic	homeostatic	ADJ
fnp-6108	135	6	microglia	microglia	NOUN
fnp-6108	135	7	in	in	ADP
fnp-6108	135	8	wildtype	wildtype	NOUN
fnp-6108	135	9	littermates	littermate	NOUN
fnp-6108	135	10	were	be	AUX
fnp-6108	135	11	gal3while	gal3while	VERB
fnp-6108	135	12	a	a	DET
fnp-6108	135	13	subset	subset	NOUN
fnp-6108	135	14	of	of	ADP
fnp-6108	135	15	microglia	microglia	NOUN
fnp-6108	135	16	in	in	ADP
fnp-6108	135	17	amyloid	amyloid	NOUN
fnp-6108	135	18	plaque	plaque	NOUN
fnp-6108	135	19	expressing	express	VERB
fnp-6108	135	20	mice	mouse	NOUN
fnp-6108	135	21	was	be	AUX
fnp-6108	135	22	gal3	gal3	NOUN
fnp-6108	135	23	+	+	PROPN
fnp-6108	135	24	.	.	PUNCT
fnp-6108	136	1	some	some	DET
fnp-6108	136	2	microglia	microglia	NOUN
fnp-6108	136	3	around	around	ADP
fnp-6108	136	4	amyloid	amyloid	NOUN
fnp-6108	136	5	plaques	plaque	NOUN
fnp-6108	136	6	increased	increase	VERB
fnp-6108	136	7	phagocytosis	phagocytosis	NOUN
fnp-6108	136	8	as	as	SCONJ
fnp-6108	136	9	evidenced	evidence	VERB
fnp-6108	136	10	cd68	cd68	PROPN
fnp-6108	136	11	that	that	SCONJ
fnp-6108	136	12	stains	stain	VERB
fnp-6108	136	13	intracellular	intracellular	ADJ
fnp-6108	136	14	lysosomes	lysosome	NOUN
fnp-6108	136	15	.	.	PUNCT
fnp-6108	137	1	conclusions	conclusion	NOUN
fnp-6108	137	2	:	:	PUNCT
fnp-6108	137	3	combining	combine	VERB
fnp-6108	137	4	endogenous	endogenous	ADJ
fnp-6108	137	5	microglia	microglia	ADJ
fnp-6108	137	6	fluorescence	fluorescence	NOUN
fnp-6108	137	7	,	,	PUNCT
fnp-6108	137	8	confocal	confocal	ADJ
fnp-6108	137	9	3d	3d	NUM
fnp-6108	137	10	imaging	imaging	NOUN
fnp-6108	137	11	of	of	ADP
fnp-6108	137	12	thick	thick	ADJ
fnp-6108	137	13	sections	section	NOUN
fnp-6108	137	14	and	and	CCONJ
fnp-6108	137	15	digital	digital	ADJ
fnp-6108	137	16	reconstruction	reconstruction	NOUN
fnp-6108	137	17	gave	give	VERB
fnp-6108	137	18	us	we	PRON
fnp-6108	137	19	an	an	DET
fnp-6108	137	20	unprecedented	unprecedented	ADJ
fnp-6108	137	21	visibility	visibility	NOUN
fnp-6108	137	22	of	of	ADP
fnp-6108	137	23	microglia	microglia	ADJ
fnp-6108	137	24	interactions	interaction	NOUN
fnp-6108	137	25	with	with	ADP
fnp-6108	137	26	an	an	DET
fnp-6108	137	27	amyloid	amyloid	NOUN
fnp-6108	137	28	plaque	plaque	NOUN
fnp-6108	137	29	.	.	PUNCT
fnp-6108	138	1	this	this	DET
fnp-6108	138	2	approach	approach	NOUN
fnp-6108	138	3	help	help	VERB
fnp-6108	138	4	understand	understand	VERB
fnp-6108	138	5	the	the	DET
fnp-6108	138	6	role	role	NOUN
fnp-6108	138	7	of	of	ADP
fnp-6108	138	8	microglia	microglia	NOUN
fnp-6108	138	9	at	at	ADP
fnp-6108	138	10	different	different	ADJ
fnp-6108	138	11	stages	stage	NOUN
fnp-6108	138	12	of	of	ADP
fnp-6108	138	13	alzheimer	alzheimer	PROPN
fnp-6108	138	14	pathology	pathology	NOUN
fnp-6108	138	15	.	.	PUNCT
fnp-6108	138	16	  	  	SPACE
fnp-6108	139	1	free	free	ADJ
fnp-6108	139	2	neuropathol	neuropathol	NOUN
fnp-6108	139	3	5:30:16	5:30:16	NUM
fnp-6108	139	4	cadasil	cadasil	PROPN
fnp-6108	139	5	,	,	PUNCT
fnp-6108	139	6	the	the	DET
fnp-6108	139	7	leading	lead	VERB
fnp-6108	139	8	genetic	genetic	ADJ
fnp-6108	139	9	cause	cause	NOUN
fnp-6108	139	10	of	of	ADP
fnp-6108	139	11	small	small	ADJ
fnp-6108	139	12	vessel	vessel	NOUN
fnp-6108	139	13	disease	disease	NOUN
fnp-6108	139	14	masafumi	masafumi	PROPN
fnp-6108	139	15	ihara1	ihara1	PROPN
fnp-6108	139	16	department	department	PROPN
fnp-6108	139	17	of	of	ADP
fnp-6108	139	18	neurology	neurology	NOUN
fnp-6108	139	19	,	,	PUNCT
fnp-6108	139	20	national	national	ADJ
fnp-6108	139	21	cerebral	cerebral	ADJ
fnp-6108	139	22	and	and	CCONJ
fnp-6108	139	23	cardiovascular	cardiovascular	ADJ
fnp-6108	139	24	center	center	NOUN
fnp-6108	139	25	,	,	PUNCT
fnp-6108	139	26	osaka	osaka	PROPN
fnp-6108	139	27	,	,	PUNCT
fnp-6108	139	28	japan	japan	PROPN
fnp-6108	139	29	small	small	ADJ
fnp-6108	139	30	vessel	vessel	NOUN
fnp-6108	139	31	disease	disease	NOUN
fnp-6108	139	32	(	(	PUNCT
fnp-6108	139	33	svd	svd	PROPN
fnp-6108	139	34	)	)	PUNCT
fnp-6108	139	35	is	be	AUX
fnp-6108	139	36	a	a	DET
fnp-6108	139	37	term	term	NOUN
fnp-6108	139	38	that	that	PRON
fnp-6108	139	39	encompasses	encompass	VERB
fnp-6108	139	40	a	a	DET
fnp-6108	139	41	variety	variety	NOUN
fnp-6108	139	42	of	of	ADP
fnp-6108	139	43	diseases	disease	NOUN
fnp-6108	139	44	and	and	CCONJ
fnp-6108	139	45	syndromes	syndrome	NOUN
fnp-6108	139	46	caused	cause	VERB
fnp-6108	139	47	by	by	ADP
fnp-6108	139	48	pathological	pathological	ADJ
fnp-6108	139	49	changes	change	NOUN
fnp-6108	139	50	in	in	ADP
fnp-6108	139	51	the	the	DET
fnp-6108	139	52	small	small	ADJ
fnp-6108	139	53	blood	blood	NOUN
fnp-6108	139	54	vessels	vessel	NOUN
fnp-6108	139	55	of	of	ADP
fnp-6108	139	56	the	the	DET
fnp-6108	139	57	brain	brain	NOUN
fnp-6108	139	58	as	as	ADP
fnp-6108	139	59	a	a	DET
fnp-6108	139	60	result	result	NOUN
fnp-6108	139	61	of	of	ADP
fnp-6108	139	62	ageing	age	VERB
fnp-6108	139	63	,	,	PUNCT
fnp-6108	139	64	environmental	environmental	ADJ
fnp-6108	139	65	and	and	CCONJ
fnp-6108	139	66	genetic	genetic	ADJ
fnp-6108	139	67	factors	factor	NOUN
fnp-6108	139	68	.	.	PUNCT
fnp-6108	140	1	approximately	approximately	ADV
fnp-6108	140	2	30	30	NUM
fnp-6108	140	3	 	 	SPACE
fnp-6108	140	4	%	%	NOUN
fnp-6108	140	5	of	of	ADP
fnp-6108	140	6	ischaemic	ischaemic	ADJ
fnp-6108	140	7	strokes	stroke	NOUN
fnp-6108	140	8	,	,	PUNCT
fnp-6108	140	9	almost	almost	ADV
fnp-6108	140	10	all	all	PRON
fnp-6108	140	11	haemorrhagic	haemorrhagic	ADJ
fnp-6108	140	12	strokes	stroke	NOUN
fnp-6108	140	13	and	and	CCONJ
fnp-6108	140	14	almost	almost	ADV
fnp-6108	140	15	half	half	NOUN
fnp-6108	140	16	of	of	ADP
fnp-6108	140	17	vascular	vascular	ADJ
fnp-6108	140	18	dementia	dementia	NOUN
fnp-6108	140	19	are	be	AUX
fnp-6108	140	20	caused	cause	VERB
fnp-6108	140	21	by	by	ADP
fnp-6108	140	22	cerebral	cerebral	ADJ
fnp-6108	140	23	small	small	ADJ
fnp-6108	140	24	vessel	vessel	NOUN
fnp-6108	140	25	disease	disease	NOUN
fnp-6108	140	26	.	.	PUNCT
fnp-6108	141	1	therefore	therefore	ADV
fnp-6108	141	2	,	,	PUNCT
fnp-6108	141	3	there	there	PRON
fnp-6108	141	4	are	be	VERB
fnp-6108	141	5	no	no	DET
fnp-6108	141	6	comprehensive	comprehensive	ADJ
fnp-6108	141	7	diagnostic	diagnostic	ADJ
fnp-6108	141	8	criteria	criterion	NOUN
fnp-6108	141	9	for	for	ADP
fnp-6108	141	10	all	all	PRON
fnp-6108	141	11	of	of	ADP
fnp-6108	141	12	them	they	PRON
fnp-6108	141	13	,	,	PUNCT
fnp-6108	141	14	but	but	CCONJ
fnp-6108	141	15	diagnostic	diagnostic	ADJ
fnp-6108	141	16	criteria	criterion	NOUN
fnp-6108	141	17	have	have	AUX
fnp-6108	141	18	been	be	AUX
fnp-6108	141	19	developed	develop	VERB
fnp-6108	141	20	for	for	ADP
fnp-6108	141	21	some	some	DET
fnp-6108	141	22	inherited	inherit	VERB
fnp-6108	141	23	svds	svds	NOUN
fnp-6108	141	24	.	.	PUNCT
fnp-6108	142	1	among	among	ADP
fnp-6108	142	2	these	these	PRON
fnp-6108	142	3	,	,	PUNCT
fnp-6108	142	4	cadasil	cadasil	PROPN
fnp-6108	142	5	is	be	AUX
fnp-6108	142	6	the	the	DET
fnp-6108	142	7	most	most	ADV
fnp-6108	142	8	common	common	ADJ
fnp-6108	142	9	inherited	inherit	VERB
fnp-6108	142	10	svd	svd	PROPN
fnp-6108	142	11	caused	cause	VERB
fnp-6108	142	12	by	by	ADP
fnp-6108	142	13	notch3	notch3	ADJ
fnp-6108	142	14	mutations	mutation	NOUN
fnp-6108	142	15	,	,	PUNCT
fnp-6108	142	16	and	and	CCONJ
fnp-6108	142	17	recent	recent	ADJ
fnp-6108	142	18	genetic	genetic	ADJ
fnp-6108	142	19	analyses	analysis	NOUN
fnp-6108	142	20	show	show	VERB
fnp-6108	142	21	that	that	SCONJ
fnp-6108	142	22	the	the	DET
fnp-6108	142	23	frequency	frequency	NOUN
fnp-6108	142	24	of	of	ADP
fnp-6108	142	25	notch3	notch3	ADJ
fnp-6108	142	26	mutations	mutation	NOUN
fnp-6108	142	27	is	be	AUX
fnp-6108	142	28	0.2	0.2	NUM
fnp-6108	142	29	 	 	SPACE
fnp-6108	142	30	%	%	NOUN
fnp-6108	142	31	in	in	ADP
fnp-6108	142	32	the	the	DET
fnp-6108	142	33	uk	uk	PROPN
fnp-6108	142	34	general	general	ADJ
fnp-6108	142	35	population	population	NOUN
fnp-6108	142	36	and	and	CCONJ
fnp-6108	142	37	higher	high	ADJ
fnp-6108	142	38	in	in	ADP
fnp-6108	142	39	east	east	PROPN
fnp-6108	142	40	asia	asia	PROPN
fnp-6108	142	41	than	than	ADP
fnp-6108	142	42	in	in	ADP
fnp-6108	142	43	europe	europe	PROPN
fnp-6108	142	44	and	and	CCONJ
fnp-6108	142	45	the	the	DET
fnp-6108	142	46	usa	usa	PROPN
fnp-6108	142	47	.	.	PUNCT
fnp-6108	143	1	cadasil	cadasil	PROPN
fnp-6108	143	2	is	be	AUX
fnp-6108	143	3	characterised	characterise	VERB
fnp-6108	143	4	by	by	ADP
fnp-6108	143	5	ischaemic	ischaemic	ADJ
fnp-6108	143	6	changes	change	NOUN
fnp-6108	143	7	including	include	VERB
fnp-6108	143	8	temporopolar	temporopolar	ADJ
fnp-6108	143	9	white	white	ADJ
fnp-6108	143	10	matter	matter	NOUN
fnp-6108	143	11	changes	change	NOUN
fnp-6108	143	12	but	but	CCONJ
fnp-6108	143	13	some	some	DET
fnp-6108	143	14	notch3	notch3	ADJ
fnp-6108	143	15	mutations	mutation	NOUN
fnp-6108	143	16	are	be	AUX
fnp-6108	143	17	pro	pro	ADJ
fnp-6108	143	18	-	-	ADJ
fnp-6108	143	19	haemorrhagic	haemorrhagic	ADJ
fnp-6108	143	20	.	.	PUNCT
fnp-6108	144	1	for	for	ADP
fnp-6108	144	2	example	example	NOUN
fnp-6108	144	3	,	,	PUNCT
fnp-6108	144	4	an	an	DET
fnp-6108	144	5	east	east	ADJ
fnp-6108	144	6	asia	asia	NOUN
fnp-6108	144	7	-	-	PUNCT
fnp-6108	144	8	specific	specific	ADJ
fnp-6108	144	9	notch3	notch3	ADJ
fnp-6108	144	10	p.r75p	p.r75p	NOUN
fnp-6108	144	11	mutation	mutation	NOUN
fnp-6108	144	12	underlies	underlie	VERB
fnp-6108	144	13	haemorrhagic	haemorrhagic	ADJ
fnp-6108	144	14	presentations	presentation	NOUN
fnp-6108	144	15	with	with	ADP
fnp-6108	144	16	milder	mild	ADJ
fnp-6108	144	17	and	and	CCONJ
fnp-6108	144	18	even	even	ADV
fnp-6108	144	19	absent	absent	ADJ
fnp-6108	144	20	temporopolar	temporopolar	ADJ
fnp-6108	144	21	lesions	lesion	NOUN
fnp-6108	144	22	,	,	PUNCT
fnp-6108	144	23	based	base	VERB
fnp-6108	144	24	on	on	ADP
fnp-6108	144	25	different	different	ADJ
fnp-6108	144	26	properties	property	NOUN
fnp-6108	144	27	of	of	ADP
fnp-6108	144	28	mutant	mutant	NOUN
fnp-6108	144	29	notch3	notch3	PROPN
fnp-6108	144	30	.	.	PUNCT
fnp-6108	145	1	pathologically	pathologically	ADV
fnp-6108	145	2	,	,	PUNCT
fnp-6108	145	3	the	the	DET
fnp-6108	145	4	p.r75p	p.r75p	PROPN
fnp-6108	145	5	mutation	mutation	NOUN
fnp-6108	145	6	results	result	VERB
fnp-6108	145	7	in	in	ADP
fnp-6108	145	8	less	less	ADV
fnp-6108	145	9	vascular	vascular	ADJ
fnp-6108	145	10	notch3	notch3	ADJ
fnp-6108	145	11	extracellular	extracellular	ADJ
fnp-6108	145	12	domain	domain	NOUN
fnp-6108	145	13	accumulation	accumulation	NOUN
fnp-6108	145	14	,	,	PUNCT
fnp-6108	145	15	namely	namely	ADV
fnp-6108	145	16	granular	granular	ADJ
fnp-6108	145	17	osmiophilic	osmiophilic	NOUN
fnp-6108	145	18	material	material	NOUN
fnp-6108	145	19	,	,	PUNCT
fnp-6108	145	20	than	than	ADP
fnp-6108	145	21	the	the	DET
fnp-6108	145	22	other	other	ADJ
fnp-6108	145	23	conventional	conventional	ADJ
fnp-6108	145	24	mutations	mutation	NOUN
fnp-6108	145	25	.	.	PUNCT
fnp-6108	146	1	there	there	PRON
fnp-6108	146	2	are	be	VERB
fnp-6108	146	3	no	no	DET
fnp-6108	146	4	disease	disease	NOUN
fnp-6108	146	5	-	-	PUNCT
fnp-6108	146	6	modifying	modify	VERB
fnp-6108	146	7	treatments	treatment	NOUN
fnp-6108	146	8	for	for	ADP
fnp-6108	146	9	cadasil	cadasil	NOUN
fnp-6108	146	10	,	,	PUNCT
fnp-6108	146	11	but	but	CCONJ
fnp-6108	146	12	we	we	PRON
fnp-6108	146	13	have	have	AUX
fnp-6108	146	14	recently	recently	ADV
fnp-6108	146	15	completed	complete	VERB
fnp-6108	146	16	a	a	DET
fnp-6108	146	17	phase	phase	NOUN
fnp-6108	146	18	ii	ii	NOUN
fnp-6108	146	19	clinical	clinical	ADJ
fnp-6108	146	20	trial	trial	NOUN
fnp-6108	146	21	,	,	PUNCT
fnp-6108	146	22	the	the	DET
fnp-6108	146	23	amcad	amcad	PROPN
fnp-6108	146	24	trial	trial	NOUN
fnp-6108	146	25	,	,	PUNCT
fnp-6108	146	26	of	of	ADP
fnp-6108	146	27	a	a	DET
fnp-6108	146	28	peptide	peptide	ADJ
fnp-6108	146	29	hormone	hormone	NOUN
fnp-6108	146	30	,	,	PUNCT
fnp-6108	146	31	adrenomedullin	adrenomedullin	NOUN
fnp-6108	146	32	,	,	PUNCT
fnp-6108	146	33	in	in	ADP
fnp-6108	146	34	cadasil	cadasil	NOUN
fnp-6108	146	35	patients	patient	NOUN
fnp-6108	146	36	(	(	PUNCT
fnp-6108	146	37	https://clinicaltrials.gov/study/nct06072118	https://clinicaltrials.gov/study/nct06072118	PROPN
fnp-6108	146	38	)	)	PUNCT
fnp-6108	146	39	.	.	PUNCT
fnp-6108	147	1	an	an	DET
fnp-6108	147	2	east	east	ADJ
fnp-6108	147	3	asian	asian	ADJ
fnp-6108	147	4	cadasil	cadasil	PROPN
fnp-6108	147	5	registry	registry	NOUN
fnp-6108	147	6	has	have	AUX
fnp-6108	147	7	begun	begin	VERB
fnp-6108	147	8	enrolling	enrol	VERB
fnp-6108	147	9	1,000	1,000	NUM
fnp-6108	147	10	cadasil	cadasil	NOUN
fnp-6108	147	11	patients	patient	NOUN
fnp-6108	147	12	to	to	PART
fnp-6108	147	13	investigate	investigate	VERB
fnp-6108	147	14	the	the	DET
fnp-6108	147	15	exact	exact	ADJ
fnp-6108	147	16	mechanisms	mechanism	NOUN
fnp-6108	147	17	of	of	ADP
fnp-6108	147	18	cadasil	cadasil	NOUN
fnp-6108	147	19	and	and	CCONJ
fnp-6108	147	20	identify	identify	VERB
fnp-6108	147	21	effective	effective	ADJ
fnp-6108	147	22	treatments	treatment	NOUN
fnp-6108	147	23	.	.	PUNCT
fnp-6108	147	24	  	  	SPACE
fnp-6108	148	1	free	free	ADJ
fnp-6108	148	2	neuropathol	neuropathol	NOUN
fnp-6108	148	3	5:30:17	5:30:17	NUM
fnp-6108	148	4	genetic	genetic	ADJ
fnp-6108	148	5	subgroups	subgroup	NOUN
fnp-6108	148	6	in	in	ADP
fnp-6108	148	7	lewy	lewy	PROPN
fnp-6108	148	8	body	body	NOUN
fnp-6108	148	9	dementia	dementia	NOUN
fnp-6108	148	10	:	:	PUNCT
fnp-6108	148	11	the	the	DET
fnp-6108	148	12	influence	influence	NOUN
fnp-6108	148	13	of	of	ADP
fnp-6108	148	14	alzheimer	alzheimer	PROPN
fnp-6108	148	15	's	's	PART
fnp-6108	148	16	pathology	pathology	NOUN
fnp-6108	148	17	karri	karri	PROPN
fnp-6108	148	18	kaivola1,2	kaivola1,2	PROPN
fnp-6108	148	19	,	,	PUNCT
fnp-6108	148	20	ruth	ruth	PROPN
fnp-6108	148	21	chia3	chia3	PROPN
fnp-6108	148	22	,	,	PUNCT
fnp-6108	148	23	zalak	zalak	PROPN
fnp-6108	148	24	shah2	shah2	PROPN
fnp-6108	148	25	,	,	PUNCT
fnp-6108	148	26	international	international	PROPN
fnp-6108	148	27	lbd	lbd	PROPN
fnp-6108	148	28	genomics	genomics	PROPN
fnp-6108	148	29	consortium	consortium	PROPN
fnp-6108	148	30	,	,	PUNCT
fnp-6108	148	31	jinhui	jinhui	PROPN
fnp-6108	148	32	ding4	ding4	PROPN
fnp-6108	148	33	,	,	PUNCT
fnp-6108	148	34	raphael	raphael	PROPN
fnp-6108	148	35	gibbs4	gibbs4	PROPN
fnp-6108	148	36	,	,	PUNCT
fnp-6108	148	37	thomas	thomas	PROPN
fnp-6108	148	38	beach5	beach5	PROPN
fnp-6108	148	39	,	,	PUNCT
fnp-6108	148	40	sonja	sonja	PROPN
fnp-6108	148	41	scholz2	scholz2	PROPN
fnp-6108	148	42	university	university	PROPN
fnp-6108	148	43	of	of	ADP
fnp-6108	148	44	helsinki	helsinki	PROPN
fnp-6108	148	45	.	.	PUNCT
fnp-6108	149	1	helsinki	helsinki	PROPN
fnp-6108	149	2	,	,	PUNCT
fnp-6108	149	3	finland	finland	PROPN
fnp-6108	149	4	neurodegenerative	neurodegenerative	ADJ
fnp-6108	149	5	diseases	disease	NOUN
fnp-6108	149	6	research	research	NOUN
fnp-6108	149	7	unit	unit	NOUN
fnp-6108	149	8	,	,	PUNCT
fnp-6108	149	9	national	national	PROPN
fnp-6108	149	10	institute	institute	PROPN
fnp-6108	149	11	of	of	ADP
fnp-6108	149	12	neurological	neurological	ADJ
fnp-6108	149	13	disorders	disorder	NOUN
fnp-6108	149	14	and	and	CCONJ
fnp-6108	149	15	stroke	stroke	NOUN
fnp-6108	149	16	,	,	PUNCT
fnp-6108	149	17	bethesda	bethesda	NOUN
fnp-6108	149	18	,	,	PUNCT
fnp-6108	149	19	usa	usa	PROPN
fnp-6108	149	20	neuromuscular	neuromuscular	ADJ
fnp-6108	149	21	diseases	disease	NOUN
fnp-6108	149	22	research	research	NOUN
fnp-6108	149	23	section	section	NOUN
fnp-6108	149	24	,	,	PUNCT
fnp-6108	149	25	laboratory	laboratory	NOUN
fnp-6108	149	26	of	of	ADP
fnp-6108	149	27	neurogenetics	neurogenetic	NOUN
fnp-6108	149	28	,	,	PUNCT
fnp-6108	149	29	national	national	PROPN
fnp-6108	149	30	institute	institute	NOUN
fnp-6108	149	31	on	on	ADP
fnp-6108	149	32	aging	aging	NOUN
fnp-6108	149	33	,	,	PUNCT
fnp-6108	149	34	bethesda	bethesda	NOUN
fnp-6108	149	35	,	,	PUNCT
fnp-6108	149	36	usa	usa	PROPN
fnp-6108	149	37	computational	computational	ADJ
fnp-6108	149	38	biology	biology	NOUN
fnp-6108	149	39	group	group	NOUN
fnp-6108	149	40	,	,	PUNCT
fnp-6108	149	41	laboratory	laboratory	NOUN
fnp-6108	149	42	of	of	ADP
fnp-6108	149	43	neurogenetics	neurogenetic	NOUN
fnp-6108	149	44	,	,	PUNCT
fnp-6108	149	45	national	national	PROPN
fnp-6108	149	46	institute	institute	NOUN
fnp-6108	149	47	on	on	ADP
fnp-6108	149	48	aging	aging	NOUN
fnp-6108	149	49	,	,	PUNCT
fnp-6108	149	50	bethesda	bethesda	NOUN
fnp-6108	149	51	,	,	PUNCT
fnp-6108	149	52	usa	usa	PROPN
fnp-6108	149	53	banner	banner	PROPN
fnp-6108	149	54	sun	sun	PROPN
fnp-6108	149	55	health	health	PROPN
fnp-6108	149	56	research	research	PROPN
fnp-6108	149	57	institute	institute	PROPN
fnp-6108	149	58	,	,	PUNCT
fnp-6108	149	59	sun	sun	PROPN
fnp-6108	149	60	city	city	PROPN
fnp-6108	149	61	,	,	PUNCT
fnp-6108	149	62	arizona	arizona	PROPN
fnp-6108	149	63	,	,	PUNCT
fnp-6108	149	64	usa	usa	PROPN
fnp-6108	149	65	alzheimer	alzheimer	PROPN
fnp-6108	149	66	’s	’s	PART
fnp-6108	149	67	disease	disease	NOUN
fnp-6108	149	68	(	(	PUNCT
fnp-6108	149	69	ad	ad	NOUN
fnp-6108	149	70	)	)	PUNCT
fnp-6108	149	71	pathology	pathology	NOUN
fnp-6108	149	72	is	be	AUX
fnp-6108	149	73	common	common	ADJ
fnp-6108	149	74	in	in	ADP
fnp-6108	149	75	lewy	lewy	PROPN
fnp-6108	149	76	body	body	NOUN
fnp-6108	149	77	dementia	dementia	NOUN
fnp-6108	149	78	(	(	PUNCT
fnp-6108	149	79	lbd	lbd	PROPN
fnp-6108	149	80	)	)	PUNCT
fnp-6108	149	81	.	.	PUNCT
fnp-6108	150	1	how	how	SCONJ
fnp-6108	150	2	the	the	DET
fnp-6108	150	3	genetic	genetic	ADJ
fnp-6108	150	4	etiologies	etiology	NOUN
fnp-6108	150	5	of	of	ADP
fnp-6108	150	6	ad	ad	NOUN
fnp-6108	150	7	and	and	CCONJ
fnp-6108	150	8	lbd	lbd	PROPN
fnp-6108	150	9	overlap	overlap	NOUN
fnp-6108	150	10	is	be	AUX
fnp-6108	150	11	still	still	ADV
fnp-6108	150	12	incompletely	incompletely	ADV
fnp-6108	150	13	understood	understand	VERB
fnp-6108	150	14	.	.	PUNCT
fnp-6108	151	1	we	we	PRON
fnp-6108	151	2	aimed	aim	VERB
fnp-6108	151	3	to	to	PART
fnp-6108	151	4	elucidate	elucidate	VERB
fnp-6108	151	5	how	how	SCONJ
fnp-6108	151	6	ad	ad	NOUN
fnp-6108	151	7	pathology	pathology	NOUN
fnp-6108	151	8	affects	affect	VERB
fnp-6108	151	9	genetic	genetic	ADJ
fnp-6108	151	10	associations	association	NOUN
fnp-6108	151	11	in	in	ADP
fnp-6108	151	12	lbd	lbd	PROPN
fnp-6108	151	13	.	.	PUNCT
fnp-6108	152	1	we	we	PRON
fnp-6108	152	2	used	use	VERB
fnp-6108	152	3	two	two	NUM
fnp-6108	152	4	whole	whole	ADJ
fnp-6108	152	5	-	-	PUNCT
fnp-6108	152	6	genome	genome	NOUN
fnp-6108	152	7	sequenced	sequence	VERB
fnp-6108	152	8	cohorts	cohort	NOUN
fnp-6108	152	9	.	.	PUNCT
fnp-6108	153	1	the	the	DET
fnp-6108	153	2	first	first	ADJ
fnp-6108	153	3	cohort	cohort	NOUN
fnp-6108	153	4	was	be	AUX
fnp-6108	153	5	a	a	DET
fnp-6108	153	6	case	case	NOUN
fnp-6108	153	7	-	-	PUNCT
fnp-6108	153	8	control	control	NOUN
fnp-6108	153	9	cohort	cohort	NOUN
fnp-6108	153	10	with	with	ADP
fnp-6108	153	11	495	495	NUM
fnp-6108	153	12	neuropathologically	neuropathologically	ADV
fnp-6108	153	13	examined	examine	VERB
fnp-6108	153	14	lbd	lbd	PROPN
fnp-6108	153	15	patients	patient	NOUN
fnp-6108	153	16	and	and	CCONJ
fnp-6108	153	17	2928	2928	NUM
fnp-6108	153	18	controls	control	NOUN
fnp-6108	153	19	.	.	PUNCT
fnp-6108	154	1	the	the	DET
fnp-6108	154	2	second	second	ADJ
fnp-6108	154	3	was	be	AUX
fnp-6108	154	4	a	a	DET
fnp-6108	154	5	brain	brain	NOUN
fnp-6108	154	6	bank	bank	NOUN
fnp-6108	154	7	cohort	cohort	NOUN
fnp-6108	154	8	that	that	PRON
fnp-6108	154	9	consisted	consist	VERB
fnp-6108	154	10	of	of	ADP
fnp-6108	154	11	727	727	NUM
fnp-6108	154	12	brains	brain	NOUN
fnp-6108	154	13	with	with	ADP
fnp-6108	154	14	alpha	alpha	NOUN
fnp-6108	154	15	-	-	PUNCT
fnp-6108	154	16	synuclein	synuclein	NOUN
fnp-6108	154	17	,	,	PUNCT
fnp-6108	154	18	neuritic	neuritic	ADJ
fnp-6108	154	19	plaque	plaque	NOUN
fnp-6108	154	20	and	and	CCONJ
fnp-6108	154	21	neurofibrillary	neurofibrillary	ADJ
fnp-6108	154	22	tangle	tangle	NOUN
fnp-6108	154	23	scores	score	NOUN
fnp-6108	154	24	across	across	ADP
fnp-6108	154	25	regions	region	NOUN
fnp-6108	154	26	of	of	ADP
fnp-6108	154	27	the	the	DET
fnp-6108	154	28	brain	brain	NOUN
fnp-6108	154	29	.	.	PUNCT
fnp-6108	155	1	apoe	apoe	PROPN
fnp-6108	155	2	e4	e4	PROPN
fnp-6108	155	3	associated	associate	VERB
fnp-6108	155	4	with	with	ADP
fnp-6108	155	5	lbd	lbd	PROPN
fnp-6108	155	6	when	when	SCONJ
fnp-6108	155	7	there	there	PRON
fnp-6108	155	8	was	be	VERB
fnp-6108	155	9	strong	strong	ADJ
fnp-6108	155	10	(	(	PUNCT
fnp-6108	155	11	p	p	X
fnp-6108	155	12	 	 	SPACE
fnp-6108	155	13	=	=	VERB
fnp-6108	155	14	 	 	SPACE
fnp-6108	155	15	1.29	1.29	NUM
fnp-6108	155	16	 	 	SPACE
fnp-6108	155	17	x	x	NUM
fnp-6108	155	18	 	 	SPACE
fnp-6108	155	19	10−32	10−32	NUM
fnp-6108	155	20	,	,	PUNCT
fnp-6108	155	21	or	or	CCONJ
fnp-6108	155	22	 	 	SPACE
fnp-6108	155	23	=	=	NOUN
fnp-6108	155	24	 	 	SPACE
fnp-6108	155	25	4.25	4.25	NUM
fnp-6108	155	26	,	,	PUNCT
fnp-6108	155	27	95	95	NUM
fnp-6108	155	28	 	 	SPACE
fnp-6108	155	29	%	%	NOUN
fnp-6108	155	30	 	 	SPACE
fnp-6108	155	31	ci	ci	NOUN
fnp-6108	155	32	 	 	SPACE
fnp-6108	155	33	=	=	NOUN
fnp-6108	155	34	 	 	SPACE
fnp-6108	155	35	3.35–5.39	3.35–5.39	NUM
fnp-6108	155	36	)	)	PUNCT
fnp-6108	155	37	or	or	CCONJ
fnp-6108	155	38	intermediate	intermediate	ADJ
fnp-6108	155	39	ad	ad	NOUN
fnp-6108	155	40	pathology	pathology	NOUN
fnp-6108	155	41	(	(	PUNCT
fnp-6108	155	42	p	p	X
fnp-6108	155	43	 	 	SPACE
fnp-6108	155	44	=	=	NOUN
fnp-6108	155	45	 	 	SPACE
fnp-6108	155	46	0.0011	0.0011	NUM
fnp-6108	155	47	,	,	PUNCT
fnp-6108	155	48	or	or	CCONJ
fnp-6108	155	49	 	 	SPACE
fnp-6108	155	50	=	=	NOUN
fnp-6108	155	51	 	 	SPACE
fnp-6108	155	52	2.31	2.31	NUM
fnp-6108	155	53	,	,	PUNCT
fnp-6108	155	54	95	95	NUM
fnp-6108	155	55	 	 	SPACE
fnp-6108	155	56	%	%	NOUN
fnp-6108	155	57	 	 	SPACE
fnp-6108	155	58	ci	ci	NOUN
fnp-6108	155	59	 	 	SPACE
fnp-6108	155	60	=	=	NOUN
fnp-6108	155	61	 	 	SPACE
fnp-6108	155	62	1.40–3.83	1.40–3.83	NUM
fnp-6108	155	63	)	)	PUNCT
fnp-6108	155	64	but	but	CCONJ
fnp-6108	155	65	not	not	PART
fnp-6108	155	66	when	when	SCONJ
fnp-6108	155	67	there	there	PRON
fnp-6108	155	68	was	be	VERB
fnp-6108	155	69	no	no	DET
fnp-6108	155	70	ad	ad	NOUN
fnp-6108	155	71	pathology	pathology	NOUN
fnp-6108	155	72	(	(	PUNCT
fnp-6108	155	73	p	p	X
fnp-6108	155	74	 	 	SPACE
fnp-6108	155	75	=	=	NOUN
fnp-6108	155	76	 	 	SPACE
fnp-6108	155	77	0.31	0.31	NUM
fnp-6108	155	78	,	,	PUNCT
fnp-6108	155	79	or	or	CCONJ
fnp-6108	155	80	 	 	SPACE
fnp-6108	155	81	=	=	NOUN
fnp-6108	155	82	 	 	SPACE
fnp-6108	155	83	0.75	0.75	NUM
fnp-6108	155	84	,	,	PUNCT
fnp-6108	155	85	95	95	NUM
fnp-6108	155	86	 	 	SPACE
fnp-6108	155	87	%	%	NOUN
fnp-6108	155	88	 	 	SPACE
fnp-6108	155	89	ci	ci	NOUN
fnp-6108	155	90	 	 	SPACE
fnp-6108	155	91	=	=	NOUN
fnp-6108	155	92	 	 	SPACE
fnp-6108	155	93	0.43–1.30	0.43–1.30	NUM
fnp-6108	155	94	)	)	PUNCT
fnp-6108	155	95	.	.	PUNCT
fnp-6108	156	1	a	a	DET
fnp-6108	156	2	regional	regional	ADJ
fnp-6108	156	3	analysis	analysis	NOUN
fnp-6108	156	4	showed	show	VERB
fnp-6108	156	5	that	that	SCONJ
fnp-6108	156	6	the	the	DET
fnp-6108	156	7	association	association	NOUN
fnp-6108	156	8	of	of	ADP
fnp-6108	156	9	apoe	apoe	PROPN
fnp-6108	156	10	e4	e4	PROPN
fnp-6108	156	11	and	and	CCONJ
fnp-6108	156	12	ad	ad	NOUN
fnp-6108	156	13	polygenic	polygenic	ADJ
fnp-6108	156	14	risk	risk	NOUN
fnp-6108	156	15	score	score	NOUN
fnp-6108	156	16	with	with	ADP
fnp-6108	156	17	alpha	alpha	NOUN
fnp-6108	156	18	-	-	PUNCT
fnp-6108	156	19	synuclein	synuclein	NOUN
fnp-6108	156	20	pathology	pathology	NOUN
fnp-6108	156	21	was	be	AUX
fnp-6108	156	22	not	not	PART
fnp-6108	156	23	universal	universal	ADJ
fnp-6108	156	24	in	in	ADP
fnp-6108	156	25	the	the	DET
fnp-6108	156	26	brain	brain	NOUN
fnp-6108	156	27	.	.	PUNCT
fnp-6108	157	1	for	for	ADP
fnp-6108	157	2	example	example	NOUN
fnp-6108	157	3	,	,	PUNCT
fnp-6108	157	4	apoe	apoe	PROPN
fnp-6108	157	5	e4	e4	PROPN
fnp-6108	157	6	(	(	PUNCT
fnp-6108	157	7	p	p	X
fnp-6108	157	8	 	 	SPACE
fnp-6108	157	9	=	=	NOUN
fnp-6108	157	10	 	 	SPACE
fnp-6108	157	11	0.0016	0.0016	NUM
fnp-6108	157	12	,	,	PUNCT
fnp-6108	157	13	or	or	CCONJ
fnp-6108	157	14	 	 	SPACE
fnp-6108	157	15	=	=	NOUN
fnp-6108	157	16	 	 	SPACE
fnp-6108	157	17	1.60	1.60	NUM
fnp-6108	157	18	,	,	PUNCT
fnp-6108	157	19	95	95	NUM
fnp-6108	157	20	 	 	SPACE
fnp-6108	157	21	%	%	NOUN
fnp-6108	157	22	 	 	SPACE
fnp-6108	157	23	ci	ci	NOUN
fnp-6108	157	24	 	 	SPACE
fnp-6108	157	25	=	=	NOUN
fnp-6108	157	26	 	 	SPACE
fnp-6108	157	27	1.20–2.12	1.20–2.12	NUM
fnp-6108	157	28	)	)	PUNCT
fnp-6108	157	29	and	and	CCONJ
fnp-6108	157	30	ad	ad	NOUN
fnp-6108	157	31	polygenic	polygenic	ADJ
fnp-6108	157	32	risk	risk	NOUN
fnp-6108	157	33	score	score	NOUN
fnp-6108	157	34	without	without	ADP
fnp-6108	157	35	apoe	apoe	NOUN
fnp-6108	157	36	(	(	PUNCT
fnp-6108	157	37	p	p	NOUN
fnp-6108	157	38	 	 	SPACE
fnp-6108	157	39	=	=	NOUN
fnp-6108	157	40	 	 	SPACE
fnp-6108	157	41	0.028	0.028	NUM
fnp-6108	157	42	,	,	PUNCT
fnp-6108	157	43	or	or	CCONJ
fnp-6108	157	44	 	 	SPACE
fnp-6108	157	45	=	=	NOUN
fnp-6108	157	46	 	 	SPACE
fnp-6108	157	47	1.21	1.21	NUM
fnp-6108	157	48	,	,	PUNCT
fnp-6108	157	49	95	95	NUM
fnp-6108	157	50	 	 	SPACE
fnp-6108	157	51	%	%	NOUN
fnp-6108	157	52	 	 	SPACE
fnp-6108	157	53	ci	ci	NOUN
fnp-6108	157	54	 	 	SPACE
fnp-6108	157	55	=	=	NOUN
fnp-6108	157	56	 	 	SPACE
fnp-6108	157	57	1.02–1.44	1.02–1.44	NUM
fnp-6108	157	58	)	)	PUNCT
fnp-6108	157	59	predicted	predict	VERB
fnp-6108	157	60	the	the	DET
fnp-6108	157	61	presence	presence	NOUN
fnp-6108	157	62	of	of	ADP
fnp-6108	157	63	alpha	alpha	NOUN
fnp-6108	157	64	-	-	PUNCT
fnp-6108	157	65	synuclein	synuclein	NOUN
fnp-6108	157	66	in	in	ADP
fnp-6108	157	67	the	the	DET
fnp-6108	157	68	olfactory	olfactory	NOUN
fnp-6108	157	69	bulb	bulb	NOUN
fnp-6108	157	70	/	/	SYM
fnp-6108	157	71	tract	tract	NOUN
fnp-6108	157	72	,	,	PUNCT
fnp-6108	157	73	but	but	CCONJ
fnp-6108	157	74	neither	neither	DET
fnp-6108	157	75	apoe	apoe	PROPN
fnp-6108	157	76	e4	e4	PROPN
fnp-6108	157	77	(	(	PUNCT
fnp-6108	157	78	p	p	X
fnp-6108	157	79	 	 	SPACE
fnp-6108	157	80	=	=	NOUN
fnp-6108	157	81	 	 	SPACE
fnp-6108	157	82	0.24	0.24	NUM
fnp-6108	157	83	)	)	PUNCT
fnp-6108	157	84	nor	nor	CCONJ
fnp-6108	157	85	ad	ad	NOUN
fnp-6108	157	86	polygenic	polygenic	ADJ
fnp-6108	157	87	risk	risk	NOUN
fnp-6108	157	88	score	score	NOUN
fnp-6108	157	89	without	without	ADP
fnp-6108	157	90	apoe	apoe	NOUN
fnp-6108	157	91	(	(	PUNCT
fnp-6108	157	92	p	p	NOUN
fnp-6108	157	93	 	 	SPACE
fnp-6108	157	94	=	=	NOUN
fnp-6108	157	95	 	 	SPACE
fnp-6108	157	96	0.12	0.12	NUM
fnp-6108	157	97	)	)	PUNCT
fnp-6108	157	98	predicted	predict	VERB
fnp-6108	157	99	alpha	alpha	NOUN
fnp-6108	157	100	-	-	PUNCT
fnp-6108	157	101	synuclein	synuclein	NOUN
fnp-6108	157	102	in	in	ADP
fnp-6108	157	103	the	the	DET
fnp-6108	157	104	brainstem	brainstem	NOUN
fnp-6108	157	105	ix	ix	ADP
fnp-6108	157	106	/	/	SYM
fnp-6108	157	107	x	x	NOUN
fnp-6108	157	108	region	region	NOUN
fnp-6108	157	109	.	.	PUNCT
fnp-6108	158	1	in	in	ADP
fnp-6108	158	2	conclusion	conclusion	NOUN
fnp-6108	158	3	,	,	PUNCT
fnp-6108	158	4	ad	ad	NOUN
fnp-6108	158	5	pathology	pathology	NOUN
fnp-6108	158	6	affects	affect	VERB
fnp-6108	158	7	the	the	DET
fnp-6108	158	8	genetic	genetic	ADJ
fnp-6108	158	9	associations	association	NOUN
fnp-6108	158	10	of	of	ADP
fnp-6108	158	11	lbd	lbd	PROPN
fnp-6108	158	12	and	and	CCONJ
fnp-6108	158	13	demonstrates	demonstrate	VERB
fnp-6108	158	14	putative	putative	ADJ
fnp-6108	158	15	lbd	lbd	PROPN
fnp-6108	158	16	subgroups	subgroup	NOUN
fnp-6108	158	17	.	.	PUNCT
fnp-6108	158	18	  	  	SPACE
fnp-6108	159	1	free	free	ADJ
fnp-6108	159	2	neuropathol	neuropathol	NOUN
fnp-6108	159	3	5:30:18	5:30:18	PROPN
fnp-6108	159	4	association	association	NOUN
fnp-6108	159	5	of	of	ADP
fnp-6108	159	6	cardiac	cardiac	ADJ
fnp-6108	159	7	sympathetic	sympathetic	ADJ
fnp-6108	159	8	denervation	denervation	NOUN
fnp-6108	159	9	with	with	ADP
fnp-6108	159	10	lewy	lewy	PROPN
fnp-6108	159	11	pathology	pathology	PROPN
fnp-6108	159	12	and	and	CCONJ
fnp-6108	159	13	its	its	PRON
fnp-6108	159	14	progression	progression	NOUN
fnp-6108	159	15	patterns	pattern	NOUN
fnp-6108	159	16	ville	ville	X
fnp-6108	159	17	kivistö1	kivistö1	PROPN
fnp-6108	159	18	,	,	PUNCT
fnp-6108	159	19	eloise	eloise	PROPN
fnp-6108	159	20	kok1	kok1	PROPN
fnp-6108	159	21	,	,	PUNCT
fnp-6108	159	22	mikko	mikko	PROPN
fnp-6108	159	23	mäyränpää1,2	mäyränpää1,2	PROPN
fnp-6108	159	24	,	,	PUNCT
fnp-6108	159	25	tuomo	tuomo	PROPN
fnp-6108	159	26	polvikoski3	polvikoski3	PROPN
fnp-6108	159	27	,	,	PUNCT
fnp-6108	159	28	liisa	liisa	VERB
fnp-6108	159	29	myllykangas1,2	myllykangas1,2	PROPN
fnp-6108	159	30	department	department	NOUN
fnp-6108	159	31	of	of	ADP
fnp-6108	159	32	pathology	pathology	PROPN
fnp-6108	159	33	,	,	PUNCT
fnp-6108	159	34	university	university	PROPN
fnp-6108	159	35	of	of	ADP
fnp-6108	159	36	helsinki	helsinki	PROPN
fnp-6108	159	37	,	,	PUNCT
fnp-6108	159	38	helsinki	helsinki	PROPN
fnp-6108	159	39	,	,	PUNCT
fnp-6108	159	40	finland	finland	PROPN
fnp-6108	159	41	department	department	PROPN
fnp-6108	159	42	of	of	ADP
fnp-6108	159	43	pathology	pathology	PROPN
fnp-6108	159	44	,	,	PUNCT
fnp-6108	159	45	hus	hus	CCONJ
fnp-6108	159	46	diagnostic	diagnostic	ADJ
fnp-6108	159	47	center	center	NOUN
fnp-6108	159	48	,	,	PUNCT
fnp-6108	159	49	helsinki	helsinki	PROPN
fnp-6108	159	50	university	university	PROPN
fnp-6108	159	51	hospital	hospital	NOUN
fnp-6108	159	52	,	,	PUNCT
fnp-6108	159	53	helsinki	helsinki	PROPN
fnp-6108	159	54	,	,	PUNCT
fnp-6108	159	55	finland	finland	PROPN
fnp-6108	159	56	translational	translational	ADJ
fnp-6108	159	57	and	and	CCONJ
fnp-6108	159	58	clinical	clinical	ADJ
fnp-6108	159	59	research	research	PROPN
fnp-6108	159	60	institute	institute	PROPN
fnp-6108	159	61	,	,	PUNCT
fnp-6108	159	62	newcastle	newcastle	PROPN
fnp-6108	159	63	university	university	PROPN
fnp-6108	159	64	,	,	PUNCT
fnp-6108	159	65	newcastle	newcastle	PROPN
fnp-6108	159	66	upon	upon	SCONJ
fnp-6108	159	67	tyne	tyne	PROPN
fnp-6108	159	68	,	,	PUNCT
fnp-6108	159	69	united	united	ADJ
fnp-6108	159	70	kingdom	kingdom	PROPN
fnp-6108	159	71	objectives	objective	NOUN
fnp-6108	159	72	:	:	PUNCT
fnp-6108	159	73	neuropathological	neuropathological	ADJ
fnp-6108	159	74	and	and	CCONJ
fnp-6108	159	75	clinical	clinical	ADJ
fnp-6108	159	76	data	datum	NOUN
fnp-6108	159	77	have	have	AUX
fnp-6108	159	78	led	lead	VERB
fnp-6108	159	79	to	to	ADP
fnp-6108	159	80	hypotheses	hypothesis	NOUN
fnp-6108	159	81	of	of	ADP
fnp-6108	159	82	multiple	multiple	ADJ
fnp-6108	159	83	subtypes	subtype	NOUN
fnp-6108	159	84	underlying	underlie	VERB
fnp-6108	159	85	lewy	lewy	ADJ
fnp-6108	159	86	pathology	pathology	NOUN
fnp-6108	159	87	(	(	PUNCT
fnp-6108	159	88	lp	lp	NOUN
fnp-6108	159	89	)	)	PUNCT
fnp-6108	159	90	in	in	ADP
fnp-6108	159	91	parkinson	parkinson	NOUN
fnp-6108	159	92	’s	’s	PART
fnp-6108	159	93	disease	disease	NOUN
fnp-6108	159	94	and	and	CCONJ
fnp-6108	159	95	dementia	dementia	NOUN
fnp-6108	159	96	with	with	ADP
fnp-6108	159	97	lewy	lewy	PROPN
fnp-6108	159	98	bodies	body	NOUN
fnp-6108	159	99	.	.	PUNCT
fnp-6108	160	1	the	the	DET
fnp-6108	160	2	main	main	ADJ
fnp-6108	160	3	differentiating	differentiate	VERB
fnp-6108	160	4	factor	factor	NOUN
fnp-6108	160	5	is	be	AUX
fnp-6108	160	6	whether	whether	SCONJ
fnp-6108	160	7	the	the	DET
fnp-6108	160	8	starting	starting	NOUN
fnp-6108	160	9	point	point	NOUN
fnp-6108	160	10	is	be	AUX
fnp-6108	160	11	in	in	ADP
fnp-6108	160	12	the	the	DET
fnp-6108	160	13	peripheral	peripheral	ADJ
fnp-6108	160	14	nervous	nervous	ADJ
fnp-6108	160	15	system	system	NOUN
fnp-6108	160	16	or	or	CCONJ
fnp-6108	160	17	the	the	DET
fnp-6108	160	18	cerebrum	cerebrum	NOUN
fnp-6108	160	19	,	,	PUNCT
fnp-6108	160	20	leading	lead	VERB
fnp-6108	160	21	to	to	ADP
fnp-6108	160	22	a	a	DET
fnp-6108	160	23	caudo	caudo	NOUN
fnp-6108	160	24	-	-	PUNCT
fnp-6108	160	25	rostral	rostral	ADJ
fnp-6108	160	26	or	or	CCONJ
fnp-6108	160	27	amygdala	amygdala	NOUN
fnp-6108	160	28	-	-	PUNCT
fnp-6108	160	29	based	base	VERB
fnp-6108	160	30	distribution	distribution	NOUN
fnp-6108	160	31	of	of	ADP
fnp-6108	160	32	lp	lp	NOUN
fnp-6108	160	33	,	,	PUNCT
fnp-6108	160	34	respectively	respectively	ADV
fnp-6108	160	35	.	.	PUNCT
fnp-6108	161	1	a	a	DET
fnp-6108	161	2	unique	unique	ADJ
fnp-6108	161	3	feature	feature	NOUN
fnp-6108	161	4	of	of	ADP
fnp-6108	161	5	the	the	DET
fnp-6108	161	6	diseases	disease	NOUN
fnp-6108	161	7	is	be	AUX
fnp-6108	161	8	their	their	PRON
fnp-6108	161	9	peripheral	peripheral	ADJ
fnp-6108	161	10	manifestations	manifestation	NOUN
fnp-6108	161	11	,	,	PUNCT
fnp-6108	161	12	such	such	ADJ
fnp-6108	161	13	as	as	ADP
fnp-6108	161	14	cardiac	cardiac	ADJ
fnp-6108	161	15	sympathetic	sympathetic	ADJ
fnp-6108	161	16	denervation	denervation	NOUN
fnp-6108	161	17	,	,	PUNCT
fnp-6108	161	18	seen	see	VERB
fnp-6108	161	19	as	as	ADP
fnp-6108	161	20	diminished	diminish	VERB
fnp-6108	161	21	tyrosine	tyrosine	NOUN
fnp-6108	161	22	hydroxylase	hydroxylase	NOUN
fnp-6108	161	23	(	(	PUNCT
fnp-6108	161	24	th	th	NOUN
fnp-6108	161	25	)	)	PUNCT
fnp-6108	161	26	staining	staining	NOUN
fnp-6108	161	27	.	.	PUNCT
fnp-6108	162	1	materials	material	NOUN
fnp-6108	162	2	and	and	CCONJ
fnp-6108	162	3	methods	method	NOUN
fnp-6108	162	4	:	:	PUNCT
fnp-6108	162	5	to	to	PART
fnp-6108	162	6	quantify	quantify	VERB
fnp-6108	162	7	the	the	DET
fnp-6108	162	8	effect	effect	NOUN
fnp-6108	162	9	of	of	ADP
fnp-6108	162	10	lp	lp	NOUN
fnp-6108	162	11	in	in	ADP
fnp-6108	162	12	the	the	DET
fnp-6108	162	13	cns	cns	NOUN
fnp-6108	162	14	on	on	ADP
fnp-6108	162	15	cardiac	cardiac	ADJ
fnp-6108	162	16	sympathetic	sympathetic	ADJ
fnp-6108	162	17	innervation	innervation	NOUN
fnp-6108	162	18	and	and	CCONJ
fnp-6108	162	19	its	its	PRON
fnp-6108	162	20	relationship	relationship	NOUN
fnp-6108	162	21	to	to	ADP
fnp-6108	162	22	the	the	DET
fnp-6108	162	23	proposed	propose	VERB
fnp-6108	162	24	caudo	caudo	NOUN
fnp-6108	162	25	-	-	PUNCT
fnp-6108	162	26	rostral	rostral	ADJ
fnp-6108	162	27	and	and	CCONJ
fnp-6108	162	28	amygdala	amygdala	NOUN
fnp-6108	162	29	-	-	PUNCT
fnp-6108	162	30	based	base	VERB
fnp-6108	162	31	progression	progression	NOUN
fnp-6108	162	32	patterns	pattern	NOUN
fnp-6108	162	33	,	,	PUNCT
fnp-6108	162	34	we	we	PRON
fnp-6108	162	35	have	have	AUX
fnp-6108	162	36	developed	develop	VERB
fnp-6108	162	37	an	an	DET
fnp-6108	162	38	ai	ai	ADJ
fnp-6108	162	39	algorithm	algorithm	NOUN
fnp-6108	162	40	that	that	SCONJ
fnp-6108	162	41	quantifies	quantifie	NOUN
fnp-6108	162	42	th	th	VERB
fnp-6108	162	43	-	-	ADJ
fnp-6108	162	44	positive	positive	ADJ
fnp-6108	162	45	staining	staining	NOUN
fnp-6108	162	46	in	in	ADP
fnp-6108	162	47	heart	heart	NOUN
fnp-6108	162	48	tissue	tissue	NOUN
fnp-6108	162	49	and	and	CCONJ
fnp-6108	162	50	calculates	calculate	VERB
fnp-6108	162	51	its	its	PRON
fnp-6108	162	52	ratio	ratio	NOUN
fnp-6108	162	53	to	to	ADP
fnp-6108	162	54	the	the	DET
fnp-6108	162	55	analysed	analyse	VERB
fnp-6108	162	56	tissue	tissue	NOUN
fnp-6108	162	57	area	area	NOUN
fnp-6108	162	58	.	.	PUNCT
fnp-6108	163	1	preliminary	preliminary	ADJ
fnp-6108	163	2	data	datum	NOUN
fnp-6108	163	3	from	from	ADP
fnp-6108	163	4	left	left	ADJ
fnp-6108	163	5	ventricular	ventricular	ADJ
fnp-6108	163	6	samples	sample	NOUN
fnp-6108	163	7	of	of	ADP
fnp-6108	163	8	44	44	NUM
fnp-6108	163	9	subjects	subject	NOUN
fnp-6108	163	10	from	from	ADP
fnp-6108	163	11	helsinki	helsinki	PROPN
fnp-6108	163	12	biobank	biobank	PROPN
fnp-6108	163	13	and	and	CCONJ
fnp-6108	163	14	septal	septal	ADJ
fnp-6108	163	15	samples	sample	NOUN
fnp-6108	163	16	of	of	ADP
fnp-6108	163	17	135	135	NUM
fnp-6108	163	18	subjects	subject	NOUN
fnp-6108	163	19	from	from	ADP
fnp-6108	163	20	the	the	DET
fnp-6108	163	21	vantaa	vantaa	ADJ
fnp-6108	163	22	85	85	NUM
fnp-6108	163	23	+	+	SYM
fnp-6108	163	24	-study	-study	NOUN
fnp-6108	163	25	were	be	AUX
fnp-6108	163	26	analysed	analyse	VERB
fnp-6108	163	27	.	.	PUNCT
fnp-6108	164	1	results	result	NOUN
fnp-6108	164	2	:	:	PUNCT
fnp-6108	164	3	in	in	ADP
fnp-6108	164	4	the	the	DET
fnp-6108	164	5	biobank	biobank	ADJ
fnp-6108	164	6	subjects	subject	NOUN
fnp-6108	164	7	,	,	PUNCT
fnp-6108	164	8	more	more	ADV
fnp-6108	164	9	diffuse	diffuse	ADJ
fnp-6108	164	10	lp	lp	NOUN
fnp-6108	164	11	as	as	SCONJ
fnp-6108	164	12	defined	define	VERB
fnp-6108	164	13	by	by	ADP
fnp-6108	164	14	dlb	dlb	PROPN
fnp-6108	164	15	consortium	consortium	NOUN
fnp-6108	164	16	criteria	criterion	NOUN
fnp-6108	164	17	,	,	PUNCT
fnp-6108	164	18	was	be	AUX
fnp-6108	164	19	inversely	inversely	ADV
fnp-6108	164	20	correlated	correlate	VERB
fnp-6108	164	21	with	with	ADP
fnp-6108	164	22	the	the	DET
fnp-6108	164	23	th	th	NOUN
fnp-6108	164	24	-	-	PUNCT
fnp-6108	164	25	positivity	positivity	NOUN
fnp-6108	164	26	.	.	PUNCT
fnp-6108	165	1	in	in	ADP
fnp-6108	165	2	the	the	DET
fnp-6108	165	3	vantaa	vantaa	ADJ
fnp-6108	165	4	85	85	NUM
fnp-6108	165	5	+	+	SYM
fnp-6108	165	6	-subjects	-subject	NOUN
fnp-6108	165	7	,	,	PUNCT
fnp-6108	165	8	th	th	NOUN
fnp-6108	165	9	-	-	PUNCT
fnp-6108	165	10	positivity	positivity	NOUN
fnp-6108	165	11	was	be	AUX
fnp-6108	165	12	significantly	significantly	ADV
fnp-6108	165	13	lower	low	ADJ
fnp-6108	165	14	in	in	ADP
fnp-6108	165	15	subjects	subject	NOUN
fnp-6108	165	16	with	with	ADP
fnp-6108	165	17	a	a	DET
fnp-6108	165	18	caudo	caudo	NOUN
fnp-6108	165	19	-	-	PUNCT
fnp-6108	165	20	rostral	rostral	ADJ
fnp-6108	165	21	pattern	pattern	NOUN
fnp-6108	165	22	compared	compare	VERB
fnp-6108	165	23	to	to	ADP
fnp-6108	165	24	amygdala	amygdala	NOUN
fnp-6108	165	25	-	-	PUNCT
fnp-6108	165	26	based	base	VERB
fnp-6108	165	27	subjects	subject	NOUN
fnp-6108	165	28	and	and	CCONJ
fnp-6108	165	29	controls	control	NOUN
fnp-6108	165	30	with	with	ADP
fnp-6108	165	31	no	no	DET
fnp-6108	165	32	lp	lp	NOUN
fnp-6108	165	33	.	.	PUNCT
fnp-6108	166	1	th	th	NOUN
fnp-6108	166	2	-	-	PUNCT
fnp-6108	166	3	positivity	positivity	NOUN
fnp-6108	166	4	was	be	AUX
fnp-6108	166	5	not	not	PART
fnp-6108	166	6	associated	associate	VERB
fnp-6108	166	7	with	with	ADP
fnp-6108	166	8	myocardial	myocardial	ADJ
fnp-6108	166	9	infarcts	infarct	NOUN
fnp-6108	166	10	nor	nor	CCONJ
fnp-6108	166	11	with	with	ADP
fnp-6108	166	12	congo	congo	NOUN
fnp-6108	166	13	red	red	ADJ
fnp-6108	166	14	-	-	PUNCT
fnp-6108	166	15	positivity	positivity	NOUN
fnp-6108	166	16	in	in	ADP
fnp-6108	166	17	the	the	DET
fnp-6108	166	18	heart	heart	NOUN
fnp-6108	166	19	,	,	PUNCT
fnp-6108	166	20	a	a	DET
fnp-6108	166	21	marker	marker	NOUN
fnp-6108	166	22	for	for	ADP
fnp-6108	166	23	amyloidosis	amyloidosis	NOUN
fnp-6108	166	24	.	.	PUNCT
fnp-6108	167	1	conclusion	conclusion	NOUN
fnp-6108	167	2	:	:	PUNCT
fnp-6108	167	3	these	these	DET
fnp-6108	167	4	results	result	NOUN
fnp-6108	167	5	concur	concur	VERB
fnp-6108	167	6	with	with	ADP
fnp-6108	167	7	previous	previous	ADJ
fnp-6108	167	8	research	research	NOUN
fnp-6108	167	9	demonstrating	demonstrate	VERB
fnp-6108	167	10	the	the	DET
fnp-6108	167	11	degeneration	degeneration	NOUN
fnp-6108	167	12	of	of	ADP
fnp-6108	167	13	cardiac	cardiac	ADJ
fnp-6108	167	14	sympathetic	sympathetic	ADJ
fnp-6108	167	15	innervation	innervation	NOUN
fnp-6108	167	16	associated	associate	VERB
fnp-6108	167	17	with	with	ADP
fnp-6108	167	18	the	the	DET
fnp-6108	167	19	progression	progression	NOUN
fnp-6108	167	20	of	of	ADP
fnp-6108	167	21	lp	lp	NOUN
fnp-6108	167	22	in	in	ADP
fnp-6108	167	23	the	the	DET
fnp-6108	167	24	cns	cns	NOUN
fnp-6108	167	25	,	,	PUNCT
fnp-6108	167	26	and	and	CCONJ
fnp-6108	167	27	describe	describe	VERB
fnp-6108	167	28	for	for	ADP
fnp-6108	167	29	the	the	DET
fnp-6108	167	30	first	first	ADJ
fnp-6108	167	31	time	time	NOUN
fnp-6108	167	32	the	the	DET
fnp-6108	167	33	difference	difference	NOUN
fnp-6108	167	34	in	in	ADP
fnp-6108	167	35	cardiac	cardiac	ADJ
fnp-6108	167	36	pathology	pathology	NOUN
fnp-6108	167	37	manifestations	manifestation	NOUN
fnp-6108	167	38	between	between	ADP
fnp-6108	167	39	the	the	DET
fnp-6108	167	40	proposed	propose	VERB
fnp-6108	167	41	progression	progression	NOUN
fnp-6108	167	42	patterns	pattern	NOUN
fnp-6108	167	43	.	.	PUNCT
fnp-6108	167	44	  	  	SPACE
fnp-6108	168	1	free	free	ADJ
fnp-6108	168	2	neuropathol	neuropathol	NOUN
fnp-6108	168	3	5:30:19	5:30:19	NUM
fnp-6108	168	4	lewy	lewy	ADV
fnp-6108	168	5	-	-	PUNCT
fnp-6108	168	6	related	relate	VERB
fnp-6108	168	7	pathology	pathology	NOUN
fnp-6108	168	8	in	in	ADP
fnp-6108	168	9	the	the	DET
fnp-6108	168	10	tampere	tampere	NOUN
fnp-6108	168	11	sudden	sudden	ADJ
fnp-6108	168	12	death	death	NOUN
fnp-6108	168	13	study	study	NOUN
fnp-6108	168	14	eloise	eloise	PROPN
fnp-6108	168	15	kok1,2	kok1,2	PROPN
fnp-6108	168	16	,	,	PUNCT
fnp-6108	168	17	anders	anders	PROPN
fnp-6108	168	18	paetau1,3	paetau1,3	PROPN
fnp-6108	168	19	,	,	PUNCT
fnp-6108	168	20	mika	mika	PROPN
fnp-6108	168	21	martiskainen2,4	martiskainen2,4	PROPN
fnp-6108	168	22	,	,	PUNCT
fnp-6108	168	23	leo	leo	PROPN
fnp-6108	168	24	-	-	PUNCT
fnp-6108	168	25	pekka	pekka	PROPN
fnp-6108	168	26	lyytikäinen2,5	lyytikäinen2,5	PROPN
fnp-6108	168	27	,	,	PUNCT
fnp-6108	168	28	terho	terho	PROPN
fnp-6108	168	29	lehtimäki2,5	lehtimäki2,5	PROPN
fnp-6108	168	30	,	,	PUNCT
fnp-6108	168	31	pekka	pekka	PROPN
fnp-6108	168	32	karhunen2,5	karhunen2,5	PROPN
fnp-6108	168	33	,	,	PUNCT
fnp-6108	168	34	liisa	liisa	VERB
fnp-6108	168	35	myllykangas1,3	myllykangas1,3	PROPN
fnp-6108	168	36	university	university	PROPN
fnp-6108	168	37	of	of	ADP
fnp-6108	168	38	helsinki	helsinki	PROPN
fnp-6108	168	39	,	,	PUNCT
fnp-6108	168	40	helsinki	helsinki	PROPN
fnp-6108	168	41	,	,	PUNCT
fnp-6108	168	42	finland	finland	PROPN
fnp-6108	168	43	tampere	tampere	PROPN
fnp-6108	168	44	university	university	PROPN
fnp-6108	168	45	,	,	PUNCT
fnp-6108	168	46	tampere	tampere	PROPN
fnp-6108	168	47	,	,	PUNCT
fnp-6108	168	48	finland	finland	PROPN
fnp-6108	168	49	hus	hu	VERB
fnp-6108	168	50	diagnostic	diagnostic	ADJ
fnp-6108	168	51	center	center	NOUN
fnp-6108	168	52	,	,	PUNCT
fnp-6108	168	53	helsinki	helsinki	PROPN
fnp-6108	168	54	,	,	PUNCT
fnp-6108	168	55	helsinki	helsinki	PROPN
fnp-6108	168	56	,	,	PUNCT
fnp-6108	168	57	finland	finland	PROPN
fnp-6108	168	58	finnish	finnish	PROPN
fnp-6108	168	59	institute	institute	PROPN
fnp-6108	168	60	for	for	ADP
fnp-6108	168	61	health	health	NOUN
fnp-6108	168	62	and	and	CCONJ
fnp-6108	168	63	welfare	welfare	NOUN
fnp-6108	168	64	,	,	PUNCT
fnp-6108	168	65	helsinki	helsinki	PROPN
fnp-6108	168	66	,	,	PUNCT
fnp-6108	168	67	finland	finland	PROPN
fnp-6108	168	68	fimlab	fimlab	PROPN
fnp-6108	168	69	laboratories	laboratory	NOUN
fnp-6108	168	70	,	,	PUNCT
fnp-6108	168	71	tampere	tampere	NOUN
fnp-6108	168	72	,	,	PUNCT
fnp-6108	168	73	finland	finland	PROPN
fnp-6108	168	74	objectives	objective	NOUN
fnp-6108	168	75	:	:	PUNCT
fnp-6108	168	76	when	when	SCONJ
fnp-6108	168	77	treatments	treatment	NOUN
fnp-6108	168	78	against	against	ADP
fnp-6108	168	79	neurodegenerative	neurodegenerative	ADJ
fnp-6108	168	80	diseases	disease	NOUN
fnp-6108	168	81	eventuate	eventuate	VERB
fnp-6108	168	82	,	,	PUNCT
fnp-6108	168	83	the	the	DET
fnp-6108	168	84	most	most	ADV
fnp-6108	168	85	successful	successful	ADJ
fnp-6108	168	86	time	time	NOUN
fnp-6108	168	87	point	point	NOUN
fnp-6108	168	88	to	to	PART
fnp-6108	168	89	administer	administer	VERB
fnp-6108	168	90	therapies	therapy	NOUN
fnp-6108	168	91	will	will	AUX
fnp-6108	168	92	be	be	AUX
fnp-6108	168	93	the	the	DET
fnp-6108	168	94	early	early	ADJ
fnp-6108	168	95	stages	stage	NOUN
fnp-6108	168	96	,	,	PUNCT
fnp-6108	168	97	before	before	SCONJ
fnp-6108	168	98	symptoms	symptom	NOUN
fnp-6108	168	99	begin	begin	VERB
fnp-6108	168	100	to	to	PART
fnp-6108	168	101	show	show	VERB
fnp-6108	168	102	.	.	PUNCT
fnp-6108	169	1	previous	previous	ADJ
fnp-6108	169	2	studies	study	NOUN
fnp-6108	169	3	have	have	AUX
fnp-6108	169	4	found	find	VERB
fnp-6108	169	5	alpha	alpha	NOUN
fnp-6108	169	6	-	-	PUNCT
fnp-6108	169	7	synuclein	synuclein	NOUN
fnp-6108	169	8	pathology	pathology	NOUN
fnp-6108	169	9	in	in	ADP
fnp-6108	169	10	asymptomatic	asymptomatic	ADJ
fnp-6108	169	11	individuals	individual	NOUN
fnp-6108	169	12	aged	age	VERB
fnp-6108	169	13	62	62	NUM
fnp-6108	169	14	years	year	NOUN
fnp-6108	169	15	and	and	CCONJ
fnp-6108	169	16	above	above	ADV
fnp-6108	169	17	,	,	PUNCT
fnp-6108	169	18	with	with	ADP
fnp-6108	169	19	prevalences	prevalence	NOUN
fnp-6108	169	20	from	from	ADP
fnp-6108	169	21	8	8	NUM
fnp-6108	169	22	to	to	ADP
fnp-6108	169	23	17	17	NUM
fnp-6108	169	24	 	 	SPACE
fnp-6108	169	25	%	%	NOUN
fnp-6108	169	26	.	.	PUNCT
fnp-6108	170	1	materials	material	NOUN
fnp-6108	170	2	and	and	CCONJ
fnp-6108	170	3	methods	method	NOUN
fnp-6108	170	4	:	:	PUNCT
fnp-6108	170	5	we	we	PRON
fnp-6108	170	6	immunohistochemically	immunohistochemically	ADV
fnp-6108	170	7	stained	stain	VERB
fnp-6108	170	8	alpha	alpha	NOUN
fnp-6108	170	9	-	-	PUNCT
fnp-6108	170	10	synuclein	synuclein	NOUN
fnp-6108	170	11	(	(	PUNCT
fnp-6108	170	12	5g4	5g4	NUM
fnp-6108	170	13	antibody	antibody	NOUN
fnp-6108	170	14	)	)	PUNCT
fnp-6108	170	15	in	in	ADP
fnp-6108	170	16	brain	brain	NOUN
fnp-6108	170	17	tissue	tissue	NOUN
fnp-6108	170	18	samples	sample	NOUN
fnp-6108	170	19	from	from	ADP
fnp-6108	170	20	the	the	DET
fnp-6108	170	21	tampere	tampere	NOUN
fnp-6108	170	22	sudden	sudden	ADJ
fnp-6108	170	23	death	death	NOUN
fnp-6108	170	24	study	study	NOUN
fnp-6108	170	25	–	–	PUNCT
fnp-6108	170	26	a	a	DET
fnp-6108	170	27	collection	collection	NOUN
fnp-6108	170	28	of	of	ADP
fnp-6108	170	29	forensic	forensic	ADJ
fnp-6108	170	30	autopsies	autopsy	NOUN
fnp-6108	170	31	of	of	ADP
fnp-6108	170	32	individuals	individual	NOUN
fnp-6108	170	33	that	that	PRON
fnp-6108	170	34	lived	live	VERB
fnp-6108	170	35	outside	outside	ADJ
fnp-6108	170	36	hospitals	hospital	NOUN
fnp-6108	170	37	in	in	ADP
fnp-6108	170	38	tampere	tampere	NOUN
fnp-6108	170	39	and	and	CCONJ
fnp-6108	170	40	the	the	DET
fnp-6108	170	41	surrounding	surround	VERB
fnp-6108	170	42	regions	region	NOUN
fnp-6108	170	43	,	,	PUNCT
fnp-6108	170	44	finland	finland	PROPN
fnp-6108	170	45	.	.	PUNCT
fnp-6108	171	1	representative	representative	ADJ
fnp-6108	171	2	paraffin	paraffin	NOUN
fnp-6108	171	3	-	-	PUNCT
fnp-6108	171	4	embedded	embed	VERB
fnp-6108	171	5	brainstem	brainstem	NOUN
fnp-6108	171	6	tissue	tissue	NOUN
fnp-6108	171	7	regions	region	NOUN
fnp-6108	171	8	were	be	AUX
fnp-6108	171	9	available	available	ADJ
fnp-6108	171	10	from	from	ADP
fnp-6108	171	11	562	562	NUM
fnp-6108	171	12	cases	case	NOUN
fnp-6108	171	13	,	,	PUNCT
fnp-6108	171	14	aged	age	VERB
fnp-6108	171	15	16	16	NUM
fnp-6108	171	16	to	to	PART
fnp-6108	171	17	95	95	NUM
fnp-6108	171	18	years	year	NOUN
fnp-6108	171	19	,	,	PUNCT
fnp-6108	171	20	with	with	ADP
fnp-6108	171	21	a	a	DET
fnp-6108	171	22	majority	majority	NOUN
fnp-6108	171	23	males	male	NOUN
fnp-6108	171	24	(	(	PUNCT
fnp-6108	171	25	74	74	NUM
fnp-6108	171	26	 	 	SPACE
fnp-6108	171	27	%	%	NOUN
fnp-6108	171	28	vs	vs	ADP
fnp-6108	171	29	145	145	NUM
fnp-6108	171	30	females	female	NOUN
fnp-6108	171	31	)	)	PUNCT
fnp-6108	171	32	.	.	PUNCT
fnp-6108	172	1	hippocampal	hippocampal	ADJ
fnp-6108	172	2	regions	region	NOUN
fnp-6108	172	3	were	be	AUX
fnp-6108	172	4	available	available	ADJ
fnp-6108	172	5	in	in	ADP
fnp-6108	172	6	476	476	NUM
fnp-6108	172	7	cases	case	NOUN
fnp-6108	172	8	(	(	PUNCT
fnp-6108	172	9	87	87	NUM
fnp-6108	172	10	 	 	SPACE
fnp-6108	172	11	%	%	NOUN
fnp-6108	172	12	of	of	ADP
fnp-6108	172	13	brainstem	brainstem	NOUN
fnp-6108	172	14	cases	case	NOUN
fnp-6108	172	15	)	)	PUNCT
fnp-6108	172	16	.	.	PUNCT
fnp-6108	173	1	results	result	NOUN
fnp-6108	173	2	:	:	PUNCT
fnp-6108	173	3	alpha	alpha	NOUN
fnp-6108	173	4	-	-	PUNCT
fnp-6108	173	5	synuclein	synuclein	NOUN
fnp-6108	173	6	pathology	pathology	NOUN
fnp-6108	173	7	was	be	AUX
fnp-6108	173	8	seen	see	VERB
fnp-6108	173	9	in	in	ADP
fnp-6108	173	10	46	46	NUM
fnp-6108	173	11	individuals	individual	NOUN
fnp-6108	173	12	.	.	PUNCT
fnp-6108	174	1	the	the	DET
fnp-6108	174	2	youngest	young	ADJ
fnp-6108	174	3	(	(	PUNCT
fnp-6108	174	4	42y	42y	NOUN
fnp-6108	174	5	female	female	NOUN
fnp-6108	174	6	)	)	PUNCT
fnp-6108	174	7	had	have	VERB
fnp-6108	174	8	clinical	clinical	ADJ
fnp-6108	174	9	records	record	NOUN
fnp-6108	174	10	of	of	ADP
fnp-6108	174	11	parkinsonism	parkinsonism	NOUN
fnp-6108	174	12	and	and	CCONJ
fnp-6108	174	13	neuropathologically	neuropathologically	ADV
fnp-6108	174	14	determined	determine	VERB
fnp-6108	174	15	as	as	ADP
fnp-6108	174	16	multiple	multiple	ADJ
fnp-6108	174	17	system	system	NOUN
fnp-6108	174	18	atrophy	atrophy	NOUN
fnp-6108	174	19	(	(	PUNCT
fnp-6108	174	20	msa	msa	PROPN
fnp-6108	174	21	)	)	PUNCT
fnp-6108	174	22	.	.	PUNCT
fnp-6108	175	1	an	an	DET
fnp-6108	175	2	additional	additional	ADJ
fnp-6108	175	3	3	3	NUM
fnp-6108	175	4	cases	case	NOUN
fnp-6108	175	5	also	also	ADV
fnp-6108	175	6	showed	show	VERB
fnp-6108	175	7	msa	msa	PROPN
fnp-6108	175	8	-	-	PUNCT
fnp-6108	175	9	type	type	NOUN
fnp-6108	175	10	glial	glial	ADJ
fnp-6108	175	11	cytoplasmic	cytoplasmic	ADJ
fnp-6108	175	12	inclusions	inclusion	NOUN
fnp-6108	175	13	,	,	PUNCT
fnp-6108	175	14	without	without	ADP
fnp-6108	175	15	clinical	clinical	ADJ
fnp-6108	175	16	history	history	NOUN
fnp-6108	175	17	.	.	PUNCT
fnp-6108	176	1	42	42	NUM
fnp-6108	176	2	subjects	subject	NOUN
fnp-6108	176	3	showed	show	VERB
fnp-6108	176	4	lewy	lewy	ADJ
fnp-6108	176	5	-	-	PUNCT
fnp-6108	176	6	related	relate	VERB
fnp-6108	176	7	pathology	pathology	NOUN
fnp-6108	176	8	(	(	PUNCT
fnp-6108	176	9	lrp	lrp	PROPN
fnp-6108	176	10	)	)	PUNCT
fnp-6108	176	11	in	in	ADP
fnp-6108	176	12	brainstem	brainstem	NOUN
fnp-6108	176	13	.	.	PUNCT
fnp-6108	177	1	the	the	DET
fnp-6108	177	2	youngest	young	ADJ
fnp-6108	177	3	with	with	ADP
fnp-6108	177	4	lrp	lrp	PROPN
fnp-6108	177	5	was	be	AUX
fnp-6108	177	6	54	54	NUM
fnp-6108	177	7	years	year	NOUN
fnp-6108	177	8	with	with	ADP
fnp-6108	177	9	no	no	DET
fnp-6108	177	10	reported	report	VERB
fnp-6108	177	11	neurodegenerative	neurodegenerative	ADJ
fnp-6108	177	12	issues	issue	NOUN
fnp-6108	177	13	.	.	PUNCT
fnp-6108	178	1	9	9	NUM
fnp-6108	178	2	 	 	SPACE
fnp-6108	178	3	%	%	NOUN
fnp-6108	178	4	of	of	ADP
fnp-6108	178	5	those	those	PRON
fnp-6108	178	6	aged	aged	ADJ
fnp-6108	178	7	50	50	NUM
fnp-6108	178	8	years	year	NOUN
fnp-6108	178	9	or	or	CCONJ
fnp-6108	178	10	older	old	ADJ
fnp-6108	178	11	had	have	VERB
fnp-6108	178	12	lrp	lrp	NOUN
fnp-6108	178	13	with	with	ADP
fnp-6108	178	14	incidence	incidence	NOUN
fnp-6108	178	15	increasing	increase	VERB
fnp-6108	178	16	with	with	ADP
fnp-6108	178	17	age	age	NOUN
fnp-6108	178	18	.	.	PUNCT
fnp-6108	179	1	conclusion	conclusion	NOUN
fnp-6108	179	2	:	:	PUNCT
fnp-6108	179	3	this	this	PRON
fnp-6108	179	4	is	be	AUX
fnp-6108	179	5	the	the	DET
fnp-6108	179	6	first	first	ADJ
fnp-6108	179	7	investigation	investigation	NOUN
fnp-6108	179	8	of	of	ADP
fnp-6108	179	9	a	a	DET
fnp-6108	179	10	non	non	ADJ
fnp-6108	179	11	-	-	ADJ
fnp-6108	179	12	hospitalised	hospitalised	ADJ
fnp-6108	179	13	population	population	NOUN
fnp-6108	179	14	across	across	ADP
fnp-6108	179	15	the	the	DET
fnp-6108	179	16	adult	adult	NOUN
fnp-6108	179	17	life	life	NOUN
fnp-6108	179	18	span	span	NOUN
fnp-6108	179	19	showing	show	VERB
fnp-6108	179	20	the	the	DET
fnp-6108	179	21	prevalence	prevalence	NOUN
fnp-6108	179	22	of	of	ADP
fnp-6108	179	23	lrp	lrp	PROPN
fnp-6108	179	24	in	in	ADP
fnp-6108	179	25	individuals	individual	NOUN
fnp-6108	179	26	aged	age	VERB
fnp-6108	179	27	as	as	ADV
fnp-6108	179	28	young	young	ADJ
fnp-6108	179	29	as	as	ADP
fnp-6108	179	30	their	their	PRON
fnp-6108	179	31	50	50	NUM
fnp-6108	179	32	’s	’s	NOUN
fnp-6108	179	33	,	,	PUNCT
fnp-6108	179	34	suggesting	suggest	VERB
fnp-6108	179	35	lrp	lrp	PROPN
fnp-6108	179	36	starts	start	VERB
fnp-6108	179	37	earlier	early	ADV
fnp-6108	179	38	than	than	SCONJ
fnp-6108	179	39	previously	previously	ADV
fnp-6108	179	40	thought	think	VERB
fnp-6108	179	41	and	and	CCONJ
fnp-6108	179	42	is	be	AUX
fnp-6108	179	43	more	more	ADV
fnp-6108	179	44	common	common	ADJ
fnp-6108	179	45	than	than	SCONJ
fnp-6108	179	46	expected	expect	VERB
fnp-6108	179	47	in	in	ADP
fnp-6108	179	48	middle	middle	ADJ
fnp-6108	179	49	age	age	NOUN
fnp-6108	179	50	.	.	PUNCT
fnp-6108	179	51	  	  	SPACE
fnp-6108	180	1	free	free	ADJ
fnp-6108	180	2	neuropathol	neuropathol	NOUN
fnp-6108	180	3	5:30:20	5:30:20	NUM
fnp-6108	180	4	update	update	NOUN
fnp-6108	180	5	on	on	ADP
fnp-6108	180	6	tau	tau	PROPN
fnp-6108	180	7	-	-	PUNCT
fnp-6108	180	8	related	relate	VERB
fnp-6108	180	9	conditions	condition	NOUN
fnp-6108	180	10	gabor	gabor	PROPN
fnp-6108	180	11	g.	g.	PROPN
fnp-6108	180	12	kovacs1	kovacs1	PROPN
fnp-6108	181	1	university	university	PROPN
fnp-6108	181	2	of	of	ADP
fnp-6108	181	3	toronto	toronto	PROPN
fnp-6108	181	4	and	and	CCONJ
fnp-6108	181	5	university	university	PROPN
fnp-6108	181	6	health	health	NOUN
fnp-6108	181	7	network	network	NOUN
fnp-6108	181	8	,	,	PUNCT
fnp-6108	181	9	toronto	toronto	PROPN
fnp-6108	181	10	,	,	PUNCT
fnp-6108	181	11	canada	canada	PROPN
fnp-6108	181	12	assemblies	assembly	NOUN
fnp-6108	181	13	of	of	ADP
fnp-6108	181	14	the	the	DET
fnp-6108	181	15	microtubule	microtubule	NOUN
fnp-6108	181	16	-	-	PUNCT
fnp-6108	181	17	associated	associate	VERB
fnp-6108	181	18	protein	protein	NOUN
fnp-6108	181	19	tau	tau	PROPN
fnp-6108	181	20	characterise	characterise	VERB
fnp-6108	181	21	many	many	ADJ
fnp-6108	181	22	neurodegenerative	neurodegenerative	ADJ
fnp-6108	181	23	proteinopathies	proteinopathie	NOUN
fnp-6108	181	24	.	.	PUNCT
fnp-6108	182	1	tauopathies	tauopathie	NOUN
fnp-6108	182	2	are	be	AUX
fnp-6108	182	3	clinically	clinically	ADV
fnp-6108	182	4	,	,	PUNCT
fnp-6108	182	5	morphologically	morphologically	ADV
fnp-6108	182	6	and	and	CCONJ
fnp-6108	182	7	bio	bio	ADV
fnp-6108	182	8	-	-	PUNCT
fnp-6108	182	9	chemically	chemically	ADV
fnp-6108	182	10	heterogeneous	heterogeneous	ADJ
fnp-6108	182	11	neurodegenerative	neurodegenerative	ADJ
fnp-6108	182	12	diseases	disease	NOUN
fnp-6108	182	13	characterized	characterize	VERB
fnp-6108	182	14	by	by	ADP
fnp-6108	182	15	the	the	DET
fnp-6108	182	16	deposition	deposition	NOUN
fnp-6108	182	17	of	of	ADP
fnp-6108	182	18	abnormal	abnormal	ADJ
fnp-6108	182	19	tau	tau	NOUN
fnp-6108	182	20	protein	protein	NOUN
fnp-6108	182	21	in	in	ADP
fnp-6108	182	22	the	the	DET
fnp-6108	182	23	brain	brain	NOUN
fnp-6108	182	24	.	.	PUNCT
fnp-6108	183	1	the	the	DET
fnp-6108	183	2	neuropathological	neuropathological	ADJ
fnp-6108	183	3	phenotypes	phenotype	NOUN
fnp-6108	183	4	are	be	AUX
fnp-6108	183	5	distinguished	distinguish	VERB
fnp-6108	183	6	based	base	VERB
fnp-6108	183	7	on	on	ADP
fnp-6108	183	8	the	the	DET
fnp-6108	183	9	involvement	involvement	NOUN
fnp-6108	183	10	of	of	ADP
fnp-6108	183	11	different	different	ADJ
fnp-6108	183	12	anatomical	anatomical	ADJ
fnp-6108	183	13	areas	area	NOUN
fnp-6108	183	14	,	,	PUNCT
fnp-6108	183	15	cell	cell	NOUN
fnp-6108	183	16	types	type	NOUN
fnp-6108	183	17	and	and	CCONJ
fnp-6108	183	18	presence	presence	NOUN
fnp-6108	183	19	of	of	ADP
fnp-6108	183	20	distinct	distinct	ADJ
fnp-6108	183	21	isoforms	isoform	NOUN
fnp-6108	183	22	of	of	ADP
fnp-6108	183	23	tau	tau	PROPN
fnp-6108	183	24	in	in	ADP
fnp-6108	183	25	the	the	DET
fnp-6108	183	26	pathological	pathological	ADJ
fnp-6108	183	27	deposits	deposit	NOUN
fnp-6108	183	28	.	.	PUNCT
fnp-6108	184	1	electron	electron	PROPN
fnp-6108	184	2	cryo	cryo	NOUN
fnp-6108	184	3	-	-	PUNCT
fnp-6108	184	4	microscopy	microscopy	NOUN
fnp-6108	184	5	has	have	AUX
fnp-6108	184	6	revealed	reveal	VERB
fnp-6108	184	7	the	the	DET
fnp-6108	184	8	structures	structure	NOUN
fnp-6108	184	9	of	of	ADP
fnp-6108	184	10	tau	tau	PROPN
fnp-6108	184	11	protofilaments	protofilament	NOUN
fnp-6108	184	12	and	and	CCONJ
fnp-6108	184	13	the	the	DET
fnp-6108	184	14	propagation	propagation	NOUN
fnp-6108	184	15	of	of	ADP
fnp-6108	184	16	tau	tau	PROPN
fnp-6108	184	17	assemblies	assembly	NOUN
fnp-6108	184	18	has	have	AUX
fnp-6108	184	19	been	be	AUX
fnp-6108	184	20	demonstrated	demonstrate	VERB
fnp-6108	184	21	.	.	PUNCT
fnp-6108	185	1	this	this	PRON
fnp-6108	185	2	is	be	AUX
fnp-6108	185	3	essential	essential	ADJ
fnp-6108	185	4	for	for	ADP
fnp-6108	185	5	the	the	DET
fnp-6108	185	6	classification	classification	NOUN
fnp-6108	185	7	and	and	CCONJ
fnp-6108	185	8	diagnosis	diagnosis	NOUN
fnp-6108	185	9	of	of	ADP
fnp-6108	185	10	tau	tau	NOUN
fnp-6108	185	11	-	-	PUNCT
fnp-6108	185	12	related	relate	VERB
fnp-6108	185	13	conditions	condition	NOUN
fnp-6108	185	14	.	.	PUNCT
fnp-6108	186	1	mutations	mutation	NOUN
fnp-6108	186	2	in	in	ADP
fnp-6108	186	3	the	the	DET
fnp-6108	186	4	gene	gene	NOUN
fnp-6108	186	5	encoding	encode	VERB
fnp-6108	186	6	the	the	DET
fnp-6108	186	7	microtubule	microtubule	NOUN
fnp-6108	186	8	-	-	PUNCT
fnp-6108	186	9	associated	associate	VERB
fnp-6108	186	10	protein	protein	NOUN
fnp-6108	186	11	tau	tau	PROPN
fnp-6108	186	12	are	be	AUX
fnp-6108	186	13	associated	associate	VERB
fnp-6108	186	14	with	with	ADP
fnp-6108	186	15	frontotemporal	frontotemporal	ADJ
fnp-6108	186	16	dementia	dementia	NOUN
fnp-6108	186	17	and	and	CCONJ
fnp-6108	186	18	parkinsonism	parkinsonism	NOUN
fnp-6108	186	19	.	.	PUNCT
fnp-6108	187	1	main	main	ADJ
fnp-6108	187	2	tauopathy	tauopathy	ADJ
fnp-6108	187	3	forms	form	NOUN
fnp-6108	187	4	include	include	VERB
fnp-6108	187	5	pick	pick	NOUN
fnp-6108	187	6	’s	’s	PART
fnp-6108	187	7	disease	disease	NOUN
fnp-6108	187	8	,	,	PUNCT
fnp-6108	187	9	progressive	progressive	ADJ
fnp-6108	187	10	supranuclear	supranuclear	ADJ
fnp-6108	187	11	palsy	palsy	ADJ
fnp-6108	187	12	,	,	PUNCT
fnp-6108	187	13	corticobasal	corticobasal	NOUN
fnp-6108	187	14	degeneration	degeneration	NOUN
fnp-6108	187	15	,	,	PUNCT
fnp-6108	187	16	argyrophilic	argyrophilic	ADJ
fnp-6108	187	17	grain	grain	NOUN
fnp-6108	187	18	disease	disease	NOUN
fnp-6108	187	19	,	,	PUNCT
fnp-6108	187	20	primary	primary	ADJ
fnp-6108	187	21	age	age	NOUN
fnp-6108	187	22	-	-	PUNCT
fnp-6108	187	23	related	relate	VERB
fnp-6108	187	24	tauopathy	tauopathy	NOUN
fnp-6108	187	25	,	,	PUNCT
fnp-6108	187	26	formerly	formerly	ADV
fnp-6108	187	27	called	call	VERB
fnp-6108	187	28	also	also	ADV
fnp-6108	187	29	as	as	ADP
fnp-6108	187	30	neurofibrillary	neurofibrillary	ADJ
fnp-6108	187	31	tangle	tangle	NOUN
fnp-6108	187	32	-	-	PUNCT
fnp-6108	187	33	only	only	ADV
fnp-6108	187	34	dementia	dementia	NOUN
fnp-6108	187	35	,	,	PUNCT
fnp-6108	187	36	and	and	CCONJ
fnp-6108	187	37	globular	globular	ADJ
fnp-6108	187	38	glial	glial	ADJ
fnp-6108	187	39	tauopathy	tauopathy	NOUN
fnp-6108	187	40	.	.	PUNCT
fnp-6108	188	1	a	a	DET
fnp-6108	188	2	frequent	frequent	ADJ
fnp-6108	188	3	form	form	NOUN
fnp-6108	188	4	of	of	ADP
fnp-6108	188	5	tau	tau	PROPN
fnp-6108	188	6	pathology	pathology	NOUN
fnp-6108	188	7	is	be	AUX
fnp-6108	188	8	ageing	age	VERB
fnp-6108	188	9	-	-	PUNCT
fnp-6108	188	10	related	relate	VERB
fnp-6108	188	11	tau	tau	PROPN
fnp-6108	188	12	astrogliopathy	astrogliopathy	ADJ
fnp-6108	188	13	(	(	PUNCT
fnp-6108	188	14	artag	artag	ADJ
fnp-6108	188	15	)	)	PUNCT
fnp-6108	188	16	.	.	PUNCT
fnp-6108	189	1	in	in	ADP
fnp-6108	189	2	addition	addition	NOUN
fnp-6108	189	3	,	,	PUNCT
fnp-6108	189	4	further	far	ADV
fnp-6108	189	5	neurodegenerative	neurodegenerative	ADJ
fnp-6108	189	6	conditions	condition	NOUN
fnp-6108	189	7	with	with	ADP
fnp-6108	189	8	diverse	diverse	ADJ
fnp-6108	189	9	aetiologies	aetiology	NOUN
fnp-6108	189	10	may	may	AUX
fnp-6108	189	11	be	be	AUX
fnp-6108	189	12	associated	associate	VERB
fnp-6108	189	13	with	with	ADP
fnp-6108	189	14	tau	tau	PROPN
fnp-6108	189	15	pathologies	pathology	NOUN
fnp-6108	189	16	.	.	PUNCT
fnp-6108	190	1	thus	thus	ADV
fnp-6108	190	2	,	,	PUNCT
fnp-6108	190	3	the	the	DET
fnp-6108	190	4	spectrum	spectrum	NOUN
fnp-6108	190	5	of	of	ADP
fnp-6108	190	6	tau	tau	PROPN
fnp-6108	190	7	pathologies	pathology	NOUN
fnp-6108	190	8	and	and	CCONJ
fnp-6108	190	9	tauopathy	tauopathy	ADJ
fnp-6108	190	10	entities	entity	NOUN
fnp-6108	190	11	expands	expand	VERB
fnp-6108	190	12	beyond	beyond	ADP
fnp-6108	190	13	the	the	DET
fnp-6108	190	14	traditionally	traditionally	ADV
fnp-6108	190	15	discussed	discuss	VERB
fnp-6108	190	16	disease	disease	NOUN
fnp-6108	190	17	forms	form	NOUN
fnp-6108	190	18	.	.	PUNCT
fnp-6108	191	1	detailed	detailed	ADJ
fnp-6108	191	2	multidisciplinary	multidisciplinary	ADJ
fnp-6108	191	3	studies	study	NOUN
fnp-6108	191	4	are	be	AUX
fnp-6108	191	5	still	still	ADV
fnp-6108	191	6	required	require	VERB
fnp-6108	191	7	to	to	PART
fnp-6108	191	8	understand	understand	VERB
fnp-6108	191	9	their	their	PRON
fnp-6108	191	10	significance	significance	NOUN
fnp-6108	191	11	.	.	PUNCT
fnp-6108	191	12	  	  	SPACE
fnp-6108	192	1	free	free	ADJ
fnp-6108	192	2	neuropathol	neuropathol	NOUN
fnp-6108	192	3	5:30:21	5:30:21	NUM
fnp-6108	192	4	investigating	investigate	VERB
fnp-6108	192	5	choroid	choroid	NOUN
fnp-6108	192	6	plexus	plexus	NOUN
fnp-6108	192	7	and	and	CCONJ
fnp-6108	192	8	cerebrospinal	cerebrospinal	ADJ
fnp-6108	192	9	fluid	fluid	ADJ
fnp-6108	192	10	roles	role	NOUN
fnp-6108	192	11	and	and	CCONJ
fnp-6108	192	12	functions	function	NOUN
fnp-6108	192	13	in	in	ADP
fnp-6108	192	14	neurologic	neurologic	ADJ
fnp-6108	192	15	disease	disease	NOUN
fnp-6108	192	16	maria	maria	PROPN
fnp-6108	192	17	k.	k.	PROPN
fnp-6108	192	18	lehtinen1	lehtinen1	PROPN
fnp-6108	192	19	department	department	PROPN
fnp-6108	192	20	of	of	ADP
fnp-6108	192	21	pathology	pathology	PROPN
fnp-6108	192	22	,	,	PUNCT
fnp-6108	192	23	boston	boston	PROPN
fnp-6108	192	24	children	children	PROPN
fnp-6108	192	25	’s	’s	PART
fnp-6108	192	26	hospital	hospital	NOUN
fnp-6108	192	27	and	and	CCONJ
fnp-6108	192	28	harvard	harvard	PROPN
fnp-6108	192	29	medical	medical	PROPN
fnp-6108	192	30	school	school	PROPN
fnp-6108	192	31	,	,	PUNCT
fnp-6108	192	32	boston	boston	PROPN
fnp-6108	192	33	,	,	PUNCT
fnp-6108	192	34	usa	usa	PROPN
fnp-6108	192	35	the	the	DET
fnp-6108	192	36	choroid	choroid	PROPN
fnp-6108	192	37	plexus	plexus	NOUN
fnp-6108	192	38	(	(	PUNCT
fnp-6108	192	39	chp	chp	NOUN
fnp-6108	192	40	)	)	PUNCT
fnp-6108	192	41	is	be	AUX
fnp-6108	192	42	an	an	DET
fnp-6108	192	43	epithelium	epithelium	NOUN
fnp-6108	192	44	located	locate	VERB
fnp-6108	192	45	in	in	ADP
fnp-6108	192	46	each	each	DET
fnp-6108	192	47	ventricle	ventricle	NOUN
fnp-6108	192	48	in	in	ADP
fnp-6108	192	49	the	the	DET
fnp-6108	192	50	brain	brain	NOUN
fnp-6108	192	51	that	that	PRON
fnp-6108	192	52	produces	produce	VERB
fnp-6108	192	53	cerebrospinal	cerebrospinal	ADJ
fnp-6108	192	54	fluid	fluid	NOUN
fnp-6108	192	55	(	(	PUNCT
fnp-6108	192	56	csf	csf	NOUN
fnp-6108	192	57	)	)	PUNCT
fnp-6108	192	58	and	and	CCONJ
fnp-6108	192	59	secretes	secrete	VERB
fnp-6108	192	60	important	important	ADJ
fnp-6108	192	61	health	health	NOUN
fnp-6108	192	62	and	and	CCONJ
fnp-6108	192	63	growth	growth	NOUN
fnp-6108	192	64	promoting	promote	VERB
fnp-6108	192	65	factors	factor	NOUN
fnp-6108	192	66	for	for	ADP
fnp-6108	192	67	the	the	DET
fnp-6108	192	68	brain	brain	NOUN
fnp-6108	192	69	throughout	throughout	ADP
fnp-6108	192	70	life	life	NOUN
fnp-6108	192	71	.	.	PUNCT
fnp-6108	193	1	structural	structural	ADJ
fnp-6108	193	2	changes	change	NOUN
fnp-6108	193	3	in	in	ADP
fnp-6108	193	4	human	human	ADJ
fnp-6108	193	5	chp	chp	NOUN
fnp-6108	193	6	have	have	AUX
fnp-6108	193	7	been	be	AUX
fnp-6108	193	8	reported	report	VERB
fnp-6108	193	9	across	across	ADP
fnp-6108	193	10	various	various	ADJ
fnp-6108	193	11	diseases	disease	NOUN
fnp-6108	193	12	in	in	ADP
fnp-6108	193	13	case	case	NOUN
fnp-6108	193	14	reports	report	NOUN
fnp-6108	193	15	and	and	CCONJ
fnp-6108	193	16	descriptive	descriptive	ADJ
fnp-6108	193	17	work	work	NOUN
fnp-6108	193	18	.	.	PUNCT
fnp-6108	194	1	however	however	ADV
fnp-6108	194	2	,	,	PUNCT
fnp-6108	194	3	studies	study	NOUN
fnp-6108	194	4	have	have	AUX
fnp-6108	194	5	yet	yet	ADV
fnp-6108	194	6	to	to	PART
fnp-6108	194	7	pin	pin	VERB
fnp-6108	194	8	point	point	VERB
fnp-6108	194	9	the	the	DET
fnp-6108	194	10	physiological	physiological	ADJ
fnp-6108	194	11	relevance	relevance	NOUN
fnp-6108	194	12	of	of	ADP
fnp-6108	194	13	these	these	DET
fnp-6108	194	14	types	type	NOUN
fnp-6108	194	15	of	of	ADP
fnp-6108	194	16	changes	change	NOUN
fnp-6108	194	17	.	.	PUNCT
fnp-6108	195	1	for	for	ADP
fnp-6108	195	2	example	example	NOUN
fnp-6108	195	3	,	,	PUNCT
fnp-6108	195	4	the	the	DET
fnp-6108	195	5	chp	chp	NOUN
fnp-6108	195	6	forms	form	VERB
fnp-6108	195	7	a	a	DET
fnp-6108	195	8	critical	critical	ADJ
fnp-6108	195	9	brain	brain	NOUN
fnp-6108	195	10	barrier	barrier	NOUN
fnp-6108	195	11	implicated	implicate	VERB
fnp-6108	195	12	in	in	ADP
fnp-6108	195	13	coordinating	coordinate	VERB
fnp-6108	195	14	inflammatory	inflammatory	ADJ
fnp-6108	195	15	responses	response	NOUN
fnp-6108	195	16	in	in	ADP
fnp-6108	195	17	a	a	DET
fnp-6108	195	18	growing	grow	VERB
fnp-6108	195	19	number	number	NOUN
fnp-6108	195	20	of	of	ADP
fnp-6108	195	21	acute	acute	ADJ
fnp-6108	195	22	and	and	CCONJ
fnp-6108	195	23	chronic	chronic	ADJ
fnp-6108	195	24	neurologic	neurologic	ADJ
fnp-6108	195	25	conditions	condition	NOUN
fnp-6108	195	26	ranging	range	VERB
fnp-6108	195	27	from	from	ADP
fnp-6108	195	28	multiple	multiple	ADJ
fnp-6108	195	29	sclerosis	sclerosis	NOUN
fnp-6108	195	30	to	to	ADP
fnp-6108	195	31	age	age	NOUN
fnp-6108	195	32	-	-	PUNCT
fnp-6108	195	33	associated	associate	VERB
fnp-6108	195	34	neurodegenerative	neurodegenerative	ADJ
fnp-6108	195	35	diseases	disease	NOUN
fnp-6108	195	36	.	.	PUNCT
fnp-6108	196	1	we	we	PRON
fnp-6108	196	2	previously	previously	ADV
fnp-6108	196	3	developed	develop	VERB
fnp-6108	196	4	a	a	DET
fnp-6108	196	5	comprehensive	comprehensive	ADJ
fnp-6108	196	6	in	in	ADP
fnp-6108	196	7	vivo	vivo	NOUN
fnp-6108	196	8	platform	platform	NOUN
fnp-6108	196	9	using	use	VERB
fnp-6108	196	10	two	two	NUM
fnp-6108	196	11	-	-	PUNCT
fnp-6108	196	12	photon	photon	NOUN
fnp-6108	196	13	imaging	imaging	NOUN
fnp-6108	196	14	that	that	PRON
fnp-6108	196	15	enables	enable	VERB
fnp-6108	196	16	real	real	ADJ
fnp-6108	196	17	-	-	PUNCT
fnp-6108	196	18	time	time	NOUN
fnp-6108	196	19	tracking	tracking	NOUN
fnp-6108	196	20	of	of	ADP
fnp-6108	196	21	multiple	multiple	ADJ
fnp-6108	196	22	genetically	genetically	ADV
fnp-6108	196	23	accessible	accessible	ADJ
fnp-6108	196	24	chp	chp	NOUN
fnp-6108	196	25	cell	cell	NOUN
fnp-6108	196	26	types	type	NOUN
fnp-6108	196	27	.	.	PUNCT
fnp-6108	197	1	pairing	pair	VERB
fnp-6108	197	2	such	such	ADJ
fnp-6108	197	3	live	live	ADJ
fnp-6108	197	4	imaging	imaging	NOUN
fnp-6108	197	5	with	with	ADP
fnp-6108	197	6	single	single	ADJ
fnp-6108	197	7	cell	cell	NOUN
fnp-6108	197	8	transcriptomics	transcriptomic	NOUN
fnp-6108	197	9	analyses	analysis	NOUN
fnp-6108	197	10	has	have	AUX
fnp-6108	197	11	uncovered	uncover	VERB
fnp-6108	197	12	a	a	DET
fnp-6108	197	13	tightly	tightly	ADV
fnp-6108	197	14	choreographed	choreograph	VERB
fnp-6108	197	15	program	program	NOUN
fnp-6108	197	16	coordinated	coordinate	VERB
fnp-6108	197	17	by	by	ADP
fnp-6108	197	18	chp	chp	NOUN
fnp-6108	197	19	epithelial	epithelial	ADJ
fnp-6108	197	20	cells	cell	NOUN
fnp-6108	197	21	to	to	PART
fnp-6108	197	22	address	address	VERB
fnp-6108	197	23	and	and	CCONJ
fnp-6108	197	24	resolve	resolve	VERB
fnp-6108	197	25	cns	cns	NOUN
fnp-6108	197	26	infection	infection	NOUN
fnp-6108	197	27	.	.	PUNCT
fnp-6108	198	1	we	we	PRON
fnp-6108	198	2	anticipate	anticipate	VERB
fnp-6108	198	3	shared	shared	ADJ
fnp-6108	198	4	mechanisms	mechanism	NOUN
fnp-6108	198	5	are	be	AUX
fnp-6108	198	6	engaged	engage	VERB
fnp-6108	198	7	to	to	ADP
fnp-6108	198	8	varying	vary	VERB
fnp-6108	198	9	degrees	degree	NOUN
fnp-6108	198	10	across	across	ADP
fnp-6108	198	11	neurologic	neurologic	ADJ
fnp-6108	198	12	diseases	disease	NOUN
fnp-6108	198	13	where	where	SCONJ
fnp-6108	198	14	inflammation	inflammation	NOUN
fnp-6108	198	15	plays	play	VERB
fnp-6108	198	16	an	an	DET
fnp-6108	198	17	important	important	ADJ
fnp-6108	198	18	role	role	NOUN
fnp-6108	198	19	.	.	PUNCT
fnp-6108	199	1	our	our	PRON
fnp-6108	199	2	work	work	NOUN
fnp-6108	199	3	suggests	suggest	VERB
fnp-6108	199	4	the	the	DET
fnp-6108	199	5	chp	chp	NOUN
fnp-6108	199	6	acts	act	VERB
fnp-6108	199	7	as	as	ADP
fnp-6108	199	8	a	a	DET
fnp-6108	199	9	key	key	ADJ
fnp-6108	199	10	regulator	regulator	NOUN
fnp-6108	199	11	of	of	ADP
fnp-6108	199	12	brain	brain	NOUN
fnp-6108	199	13	development	development	NOUN
fnp-6108	199	14	and	and	CCONJ
fnp-6108	199	15	health	health	NOUN
fnp-6108	199	16	throughout	throughout	ADP
fnp-6108	199	17	life	life	NOUN
fnp-6108	199	18	.	.	PUNCT
fnp-6108	199	19	  	  	SPACE
fnp-6108	200	1	free	free	ADJ
fnp-6108	200	2	neuropathol	neuropathol	NOUN
fnp-6108	200	3	5:30:22	5:30:22	NUM
fnp-6108	200	4	neuropathologic	neuropathologic	ADJ
fnp-6108	200	5	change	change	NOUN
fnp-6108	200	6	in	in	ADP
fnp-6108	200	7	olfactory	olfactory	ADJ
fnp-6108	200	8	bulb	bulb	NOUN
fnp-6108	200	9	and	and	CCONJ
fnp-6108	200	10	nerve	nerve	NOUN
fnp-6108	200	11	of	of	ADP
fnp-6108	200	12	subjects	subject	NOUN
fnp-6108	200	13	with	with	ADP
fnp-6108	200	14	covid19	covid19	NOUN
fnp-6108	200	15	infection	infection	NOUN
fnp-6108	200	16	sylwia	sylwia	PROPN
fnp-6108	200	17	libard1,2	libard1,2	PROPN
fnp-6108	200	18	,	,	PUNCT
fnp-6108	200	19	irina	irina	PROPN
fnp-6108	200	20	alafuzoff1	alafuzoff1	PROPN
fnp-6108	200	21	uppsala	uppsala	PROPN
fnp-6108	200	22	university	university	PROPN
fnp-6108	200	23	hospital	hospital	NOUN
fnp-6108	200	24	,	,	PUNCT
fnp-6108	200	25	uppsala	uppsala	PROPN
fnp-6108	200	26	,	,	PUNCT
fnp-6108	200	27	sweden	sweden	PROPN
fnp-6108	200	28	uppsala	uppsala	PROPN
fnp-6108	200	29	university	university	PROPN
fnp-6108	200	30	,	,	PUNCT
fnp-6108	200	31	uppsala	uppsala	PROPN
fnp-6108	200	32	,	,	PUNCT
fnp-6108	200	33	sweden	sweden	PROPN
fnp-6108	200	34	objectives	objective	NOUN
fnp-6108	200	35	:	:	PUNCT
fnp-6108	200	36	to	to	PART
fnp-6108	200	37	study	study	VERB
fnp-6108	200	38	neuropathological	neuropathological	ADJ
fnp-6108	200	39	alterations	alteration	NOUN
fnp-6108	200	40	in	in	ADP
fnp-6108	200	41	olfactory	olfactory	ADJ
fnp-6108	200	42	bulb	bulb	NOUN
fnp-6108	200	43	/	/	SYM
fnp-6108	200	44	nerve	nerve	NOUN
fnp-6108	200	45	(	(	PUNCT
fnp-6108	200	46	ob	ob	NOUN
fnp-6108	200	47	/	/	SYM
fnp-6108	200	48	n	n	CCONJ
fnp-6108	200	49	)	)	PUNCT
fnp-6108	200	50	of	of	ADP
fnp-6108	200	51	subjects	subject	NOUN
fnp-6108	200	52	deceased	decease	VERB
fnp-6108	200	53	during	during	ADP
fnp-6108	200	54	ongoing	ongoing	ADJ
fnp-6108	200	55	covid19	covid19	NOUN
fnp-6108	200	56	infection	infection	NOUN
fnp-6108	200	57	materials	material	NOUN
fnp-6108	200	58	and	and	CCONJ
fnp-6108	200	59	methods	method	NOUN
fnp-6108	200	60	:	:	PUNCT
fnp-6108	200	61	post	post	ADJ
fnp-6108	200	62	-	-	ADJ
fnp-6108	200	63	mortem	mortem	ADJ
fnp-6108	200	64	brains	brain	NOUN
fnp-6108	200	65	and	and	CCONJ
fnp-6108	200	66	ob	ob	NOUN
fnp-6108	200	67	/	/	SYM
fnp-6108	200	68	n	n	NOUN
fnp-6108	200	69	from	from	ADP
fnp-6108	200	70	32	32	NUM
fnp-6108	200	71	subjects	subject	NOUN
fnp-6108	200	72	with	with	ADP
fnp-6108	200	73	ongoing	ongoing	ADJ
fnp-6108	200	74	covid19	covid19	NOUN
fnp-6108	200	75	infection	infection	NOUN
fnp-6108	200	76	and	and	CCONJ
fnp-6108	200	77	age	age	NOUN
fnp-6108	200	78	,	,	PUNCT
fnp-6108	200	79	gender	gender	NOUN
fnp-6108	200	80	and	and	CCONJ
fnp-6108	200	81	brain	brain	NOUN
fnp-6108	200	82	neuropathology	neuropathology	NOUN
fnp-6108	200	83	matched	match	VERB
fnp-6108	200	84	controls	control	NOUN
fnp-6108	200	85	were	be	AUX
fnp-6108	200	86	assessed	assess	VERB
fnp-6108	200	87	.	.	PUNCT
fnp-6108	201	1	the	the	DET
fnp-6108	201	2	proteinopathies	proteinopathie	NOUN
fnp-6108	201	3	in	in	ADP
fnp-6108	201	4	the	the	DET
fnp-6108	201	5	brain	brain	NOUN
fnp-6108	201	6	were	be	AUX
fnp-6108	201	7	assessed	assess	VERB
fnp-6108	201	8	in	in	ADP
fnp-6108	201	9	line	line	NOUN
fnp-6108	201	10	to	to	ADP
fnp-6108	201	11	the	the	DET
fnp-6108	201	12	international	international	ADJ
fnp-6108	201	13	consensus	consensus	NOUN
fnp-6108	201	14	criteria	criterion	NOUN
fnp-6108	201	15	.	.	PUNCT
fnp-6108	202	1	additionally	additionally	ADV
fnp-6108	202	2	,	,	PUNCT
fnp-6108	202	3	amyloid	amyloid	NOUN
fnp-6108	202	4	-	-	PUNCT
fnp-6108	202	5	β	β	X
fnp-6108	202	6	(	(	PUNCT
fnp-6108	202	7	aβ	aβ	NOUN
fnp-6108	202	8	)	)	PUNCT
fnp-6108	202	9	,	,	PUNCT
fnp-6108	202	10	hyperphosphorylated	hyperphosphorylate	VERB
fnp-6108	202	11	τ	τ	X
fnp-6108	202	12	(	(	PUNCT
fnp-6108	202	13	hpτ	hpτ	NOUN
fnp-6108	202	14	)	)	PUNCT
fnp-6108	202	15	,	,	PUNCT
fnp-6108	202	16	α	α	X
fnp-6108	202	17	-	-	PUNCT
fnp-6108	202	18	synuclein	synuclein	NOUN
fnp-6108	202	19	(	(	PUNCT
fnp-6108	202	20	α	α	NOUN
fnp-6108	202	21	-	-	PUNCT
fnp-6108	202	22	syn	syn	NOUN
fnp-6108	202	23	)	)	PUNCT
fnp-6108	202	24	,	,	PUNCT
fnp-6108	202	25	tar	tar	NOUN
fnp-6108	202	26	dna	dna	NOUN
fnp-6108	202	27	-	-	PUNCT
fnp-6108	202	28	binding	bind	VERB
fnp-6108	202	29	protein	protein	NOUN
fnp-6108	202	30	43	43	NUM
fnp-6108	202	31	(	(	PUNCT
fnp-6108	202	32	tdp43	tdp43	NOUN
fnp-6108	202	33	)	)	PUNCT
fnp-6108	202	34	as	as	ADV
fnp-6108	202	35	well	well	ADV
fnp-6108	202	36	as	as	ADP
fnp-6108	202	37	inflammatory	inflammatory	ADJ
fnp-6108	202	38	markers	marker	NOUN
fnp-6108	202	39	and	and	CCONJ
fnp-6108	202	40	an	an	DET
fnp-6108	202	41	antibody	antibody	NOUN
fnp-6108	202	42	against	against	ADP
fnp-6108	202	43	the	the	DET
fnp-6108	202	44	sars	sars	PROPN
fnp-6108	202	45	virus	virus	NOUN
fnp-6108	202	46	were	be	AUX
fnp-6108	202	47	assessed	assess	VERB
fnp-6108	202	48	within	within	ADP
fnp-6108	202	49	the	the	DET
fnp-6108	202	50	ob	ob	PROPN
fnp-6108	202	51	/	/	SYM
fnp-6108	202	52	n.	n.	NOUN
fnp-6108	202	53	results	result	NOUN
fnp-6108	202	54	:	:	PUNCT
fnp-6108	202	55	out	out	ADP
fnp-6108	202	56	of	of	ADP
fnp-6108	202	57	the	the	DET
fnp-6108	202	58	42	42	NUM
fnp-6108	202	59	cases	case	NOUN
fnp-6108	202	60	assessed	assess	VERB
fnp-6108	202	61	7	7	NUM
fnp-6108	202	62	lacked	lack	VERB
fnp-6108	202	63	proteinopathies	proteinopathie	NOUN
fnp-6108	202	64	in	in	ADP
fnp-6108	202	65	the	the	DET
fnp-6108	202	66	ob	ob	NOUN
fnp-6108	202	67	/	/	SYM
fnp-6108	202	68	n	n	NOUN
fnp-6108	202	69	whereas	whereas	SCONJ
fnp-6108	202	70	81	81	NUM
fnp-6108	202	71	 	 	SPACE
fnp-6108	202	72	%	%	NOUN
fnp-6108	202	73	displayed	display	VERB
fnp-6108	202	74	hpτ	hpτ	NOUN
fnp-6108	202	75	,	,	PUNCT
fnp-6108	202	76	41	41	NUM
fnp-6108	202	77	 	 	SPACE
fnp-6108	202	78	%	%	NOUN
fnp-6108	202	79	α	α	NOUN
fnp-6108	202	80	-	-	PUNCT
fnp-6108	202	81	syn	syn	NOUN
fnp-6108	202	82	,	,	PUNCT
fnp-6108	202	83	29	29	NUM
fnp-6108	202	84	 	 	SPACE
fnp-6108	202	85	%	%	NOUN
fnp-6108	202	86	tdp43	tdp43	NOUN
fnp-6108	202	87	and	and	CCONJ
fnp-6108	203	1	19	19	NUM
fnp-6108	203	2	 	 	SPACE
fnp-6108	203	3	%	%	NOUN
fnp-6108	203	4	aβ	aβ	NOUN
fnp-6108	203	5	.	.	PUNCT
fnp-6108	204	1	there	there	PRON
fnp-6108	204	2	was	be	VERB
fnp-6108	204	3	no	no	DET
fnp-6108	204	4	significant	significant	ADJ
fnp-6108	204	5	difference	difference	NOUN
fnp-6108	204	6	of	of	ADP
fnp-6108	204	7	incidence	incidence	NOUN
fnp-6108	204	8	of	of	ADP
fnp-6108	204	9	various	various	ADJ
fnp-6108	204	10	proteinopathies	proteinopathie	NOUN
fnp-6108	204	11	between	between	ADP
fnp-6108	204	12	the	the	DET
fnp-6108	204	13	groups	group	NOUN
fnp-6108	204	14	except	except	SCONJ
fnp-6108	204	15	for	for	ADP
fnp-6108	204	16	tdp43	tdp43	PROPN
fnp-6108	204	17	that	that	PRON
fnp-6108	204	18	was	be	AUX
fnp-6108	204	19	more	more	ADV
fnp-6108	204	20	common	common	ADJ
fnp-6108	204	21	in	in	ADP
fnp-6108	204	22	the	the	DET
fnp-6108	204	23	covid19	covid19	NOUN
fnp-6108	204	24	group	group	NOUN
fnp-6108	204	25	.	.	PUNCT
fnp-6108	205	1	the	the	DET
fnp-6108	205	2	hpτ	hpτ	NOUN
fnp-6108	205	3	,	,	PUNCT
fnp-6108	205	4	α	α	PROPN
fnp-6108	205	5	-	-	PUNCT
fnp-6108	205	6	syn	syn	PROPN
fnp-6108	205	7	and	and	CCONJ
fnp-6108	205	8	tdp43	tdp43	PROPN
fnp-6108	205	9	in	in	ADP
fnp-6108	205	10	the	the	DET
fnp-6108	205	11	brain	brain	NOUN
fnp-6108	205	12	correlated	correlate	VERB
fnp-6108	205	13	with	with	ADP
fnp-6108	205	14	hpτ	hpτ	NOUN
fnp-6108	205	15	,	,	PUNCT
fnp-6108	205	16	α	α	PROPN
fnp-6108	205	17	-	-	PUNCT
fnp-6108	205	18	syn	syn	PROPN
fnp-6108	205	19	and	and	CCONJ
fnp-6108	205	20	aβ	aβ	NOUN
fnp-6108	205	21	in	in	ADP
fnp-6108	205	22	ob	ob	NOUN
fnp-6108	205	23	/	/	SYM
fnp-6108	205	24	n	n	CCONJ
fnp-6108	205	25	,	,	PUNCT
fnp-6108	205	26	whereas	whereas	SCONJ
fnp-6108	205	27	brain	brain	NOUN
fnp-6108	205	28	aβ	aβ	PRON
fnp-6108	205	29	correlated	correlate	VERB
fnp-6108	205	30	with	with	ADP
fnp-6108	205	31	aβ	aβ	NOUN
fnp-6108	205	32	and	and	CCONJ
fnp-6108	205	33	hpτ	hpτ	NOUN
fnp-6108	205	34	in	in	ADP
fnp-6108	205	35	ob	ob	ADP
fnp-6108	205	36	/	/	SYM
fnp-6108	205	37	n.	n.	ADJ
fnp-6108	205	38	concomitant	concomitant	ADJ
fnp-6108	205	39	pathologies	pathology	NOUN
fnp-6108	205	40	in	in	ADP
fnp-6108	205	41	the	the	DET
fnp-6108	205	42	ob	ob	NOUN
fnp-6108	205	43	/	/	SYM
fnp-6108	205	44	n	n	CCONJ
fnp-6108	205	45	were	be	AUX
fnp-6108	205	46	seen	see	VERB
fnp-6108	205	47	in	in	ADP
fnp-6108	205	48	52	52	NUM
fnp-6108	205	49	 	 	SPACE
fnp-6108	205	50	%	%	NOUN
fnp-6108	205	51	of	of	ADP
fnp-6108	205	52	cases	case	NOUN
fnp-6108	205	53	.	.	PUNCT
fnp-6108	206	1	when	when	SCONJ
fnp-6108	206	2	studying	study	VERB
fnp-6108	206	3	inflammatory	inflammatory	ADJ
fnp-6108	206	4	markers	marker	NOUN
fnp-6108	206	5	there	there	PRON
fnp-6108	206	6	was	be	VERB
fnp-6108	206	7	a	a	DET
fnp-6108	206	8	pronounces	pronounce	NOUN
fnp-6108	206	9	microglial	microglial	ADJ
fnp-6108	206	10	activation	activation	NOUN
fnp-6108	206	11	within	within	ADP
fnp-6108	206	12	the	the	DET
fnp-6108	206	13	ob	ob	NOUN
fnp-6108	206	14	/	/	SYM
fnp-6108	206	15	n	n	NOUN
fnp-6108	206	16	but	but	CCONJ
fnp-6108	206	17	lymphocytosis	lymphocytosis	NOUN
fnp-6108	206	18	was	be	AUX
fnp-6108	206	19	sparse	sparse	ADJ
fnp-6108	206	20	.	.	PUNCT
fnp-6108	207	1	no	no	DET
fnp-6108	207	2	sars	sar	NOUN
fnp-6108	207	3	protein	protein	NOUN
fnp-6108	207	4	could	could	AUX
fnp-6108	207	5	be	be	AUX
fnp-6108	207	6	detected	detect	VERB
fnp-6108	207	7	within	within	ADP
fnp-6108	207	8	our	our	PRON
fnp-6108	207	9	cohort	cohort	NOUN
fnp-6108	207	10	.	.	PUNCT
fnp-6108	208	1	conclusion	conclusion	NOUN
fnp-6108	208	2	:	:	PUNCT
fnp-6108	208	3	all	all	PRON
fnp-6108	208	4	of	of	ADP
fnp-6108	208	5	the	the	DET
fnp-6108	208	6	most	most	ADV
fnp-6108	208	7	common	common	ADJ
fnp-6108	208	8	proteinopathies	proteinopathie	NOUN
fnp-6108	208	9	could	could	AUX
fnp-6108	208	10	be	be	AUX
fnp-6108	208	11	detected	detect	VERB
fnp-6108	208	12	within	within	ADP
fnp-6108	208	13	the	the	DET
fnp-6108	208	14	ob	ob	NOUN
fnp-6108	208	15	/	/	SYM
fnp-6108	208	16	n	n	PROPN
fnp-6108	208	17	but	but	CCONJ
fnp-6108	208	18	according	accord	VERB
fnp-6108	208	19	to	to	ADP
fnp-6108	208	20	our	our	PRON
fnp-6108	208	21	results	result	NOUN
fnp-6108	208	22	subjects	subject	NOUN
fnp-6108	208	23	with	with	ADP
fnp-6108	208	24	covid19	covid19	NOUN
fnp-6108	208	25	are	be	AUX
fnp-6108	208	26	predisposed	predispose	VERB
fnp-6108	208	27	to	to	PART
fnp-6108	208	28	tdp43	tdp43	VERB
fnp-6108	208	29	pathology	pathology	NOUN
fnp-6108	208	30	within	within	ADP
fnp-6108	208	31	their	their	PRON
fnp-6108	208	32	ob	ob	NOUN
fnp-6108	208	33	/	/	SYM
fnp-6108	208	34	n.	n.	NOUN
fnp-6108	208	35	there	there	PRON
fnp-6108	208	36	is	be	VERB
fnp-6108	208	37	a	a	DET
fnp-6108	208	38	substantial	substantial	ADJ
fnp-6108	208	39	microgliosis	microgliosis	NOUN
fnp-6108	208	40	within	within	ADP
fnp-6108	208	41	the	the	DET
fnp-6108	208	42	ob	ob	NOUN
fnp-6108	208	43	/	/	SYM
fnp-6108	208	44	n	n	PRON
fnp-6108	208	45	independently	independently	ADV
fnp-6108	208	46	of	of	ADP
fnp-6108	208	47	covid19	covid19	NOUN
fnp-6108	208	48	infection	infection	NOUN
fnp-6108	208	49	.	.	PUNCT
fnp-6108	209	1	the	the	DET
fnp-6108	209	2	sars	sars	PROPN
fnp-6108	209	3	virus	virus	NOUN
fnp-6108	209	4	could	could	AUX
fnp-6108	209	5	not	not	PART
fnp-6108	209	6	be	be	AUX
fnp-6108	209	7	detected	detect	VERB
fnp-6108	209	8	within	within	ADP
fnp-6108	209	9	the	the	DET
fnp-6108	209	10	ob	ob	PROPN
fnp-6108	209	11	/	/	SYM
fnp-6108	209	12	n.	n.	NOUN
fnp-6108	209	13	  	  	SPACE
fnp-6108	209	14	free	free	ADJ
fnp-6108	209	15	neuropathol	neuropathol	NOUN
fnp-6108	209	16	5:30:23	5:30:23	NUM
fnp-6108	209	17	late	late	PROPN
fnp-6108	209	18	-	-	PUNCT
fnp-6108	209	19	nc	nc	NOUN
fnp-6108	209	20	in	in	ADP
fnp-6108	209	21	the	the	DET
fnp-6108	209	22	very	very	ADV
fnp-6108	209	23	elderly	elderly	ADJ
fnp-6108	209	24	–	–	PUNCT
fnp-6108	209	25	the	the	DET
fnp-6108	209	26	population	population	NOUN
fnp-6108	209	27	-	-	PUNCT
fnp-6108	209	28	based	base	VERB
fnp-6108	209	29	vantaa	vantaa	NOUN
fnp-6108	209	30	 	 	SPACE
fnp-6108	209	31	85	85	NUM
fnp-6108	209	32	+	+	NUM
fnp-6108	209	33	study	study	NOUN
fnp-6108	209	34	elizaveta	elizaveta	PROPN
fnp-6108	209	35	mikhailenko1	mikhailenko1	PROPN
fnp-6108	209	36	,	,	PUNCT
fnp-6108	209	37	kia	kia	PROPN
fnp-6108	209	38	colangelo1	colangelo1	PROPN
fnp-6108	209	39	,	,	PUNCT
fnp-6108	209	40	jarno	jarno	PROPN
fnp-6108	209	41	tuimala1	tuimala1	PROPN
fnp-6108	209	42	,	,	PUNCT
fnp-6108	209	43	mia	mia	PROPN
fnp-6108	209	44	kero1,2	kero1,2	PROPN
fnp-6108	209	45	,	,	PUNCT
fnp-6108	209	46	sara	sara	PROPN
fnp-6108	209	47	savola1,2	savola1,2	PROPN
fnp-6108	209	48	,	,	PUNCT
fnp-6108	209	49	anna	anna	PROPN
fnp-6108	209	50	raunio1,2	raunio1,2	PROPN
fnp-6108	209	51	,	,	PUNCT
fnp-6108	209	52	eloise	eloise	PROPN
fnp-6108	209	53	h.	h.	PROPN
fnp-6108	209	54	kok1	kok1	PROPN
fnp-6108	209	55	,	,	PUNCT
fnp-6108	209	56	maarit	maarit	PROPN
fnp-6108	209	57	tanskanen1	tanskanen1	PROPN
fnp-6108	209	58	,	,	PUNCT
fnp-6108	209	59	mira	mira	PROPN
fnp-6108	209	60	mäkelä1	mäkelä1	PROPN
fnp-6108	209	61	,	,	PUNCT
fnp-6108	209	62	henri	henri	PROPN
fnp-6108	209	63	puttonen1,2	puttonen1,2	PROPN
fnp-6108	209	64	,	,	PUNCT
fnp-6108	209	65	mikko	mikko	PROPN
fnp-6108	209	66	i.	i.	PROPN
fnp-6108	209	67	mäyränpää1,2	mäyränpää1,2	PROPN
fnp-6108	209	68	,	,	PUNCT
fnp-6108	209	69	darshan	darshan	ADP
fnp-6108	209	70	kumar3	kumar3	PROPN
fnp-6108	209	71	,	,	PUNCT
fnp-6108	209	72	karri	karri	PROPN
fnp-6108	209	73	kaivola4,5	kaivola4,5	PROPN
fnp-6108	209	74	,	,	PUNCT
fnp-6108	209	75	anders	ander	NOUN
fnp-6108	209	76	paetau1,2	paetau1,2	PROPN
fnp-6108	209	77	,	,	PUNCT
fnp-6108	209	78	pentti	pentti	PROPN
fnp-6108	209	79	j.	j.	PROPN
fnp-6108	209	80	tienari4,5	tienari4,5	PROPN
fnp-6108	209	81	,	,	PUNCT
fnp-6108	209	82	tuomo	tuomo	ADJ
fnp-6108	209	83	polvikoski6	polvikoski6	NOUN
fnp-6108	209	84	,	,	PUNCT
fnp-6108	209	85	liisa	liisa	VERB
fnp-6108	209	86	myllykangas1,2	myllykangas1,2	PROPN
fnp-6108	209	87	department	department	NOUN
fnp-6108	209	88	of	of	ADP
fnp-6108	209	89	pathology	pathology	PROPN
fnp-6108	209	90	,	,	PUNCT
fnp-6108	209	91	university	university	PROPN
fnp-6108	209	92	of	of	ADP
fnp-6108	209	93	helsinki	helsinki	PROPN
fnp-6108	209	94	,	,	PUNCT
fnp-6108	209	95	helsinki	helsinki	PROPN
fnp-6108	209	96	,	,	PUNCT
fnp-6108	209	97	finland	finland	PROPN
fnp-6108	209	98	department	department	PROPN
fnp-6108	209	99	of	of	ADP
fnp-6108	209	100	pathology	pathology	PROPN
fnp-6108	209	101	,	,	PUNCT
fnp-6108	209	102	hus	hus	CCONJ
fnp-6108	209	103	diagnostic	diagnostic	ADJ
fnp-6108	209	104	center	center	NOUN
fnp-6108	209	105	,	,	PUNCT
fnp-6108	209	106	helsinki	helsinki	PROPN
fnp-6108	209	107	university	university	PROPN
fnp-6108	209	108	hospital	hospital	NOUN
fnp-6108	209	109	,	,	PUNCT
fnp-6108	209	110	helsinki	helsinki	PROPN
fnp-6108	209	111	,	,	PUNCT
fnp-6108	209	112	finland	finland	PROPN
fnp-6108	209	113	aiforia	aiforia	PROPN
fnp-6108	209	114	technologies	technologies	PROPN
fnp-6108	209	115	plc	plc	PROPN
fnp-6108	209	116	.	.	PROPN
fnp-6108	209	117	,	,	PUNCT
fnp-6108	209	118	helsinki	helsinki	PROPN
fnp-6108	209	119	,	,	PUNCT
fnp-6108	209	120	finland	finland	PROPN
fnp-6108	209	121	translational	translational	ADJ
fnp-6108	209	122	immunology	immunology	NOUN
fnp-6108	209	123	,	,	PUNCT
fnp-6108	209	124	research	research	NOUN
fnp-6108	209	125	programs	program	NOUN
fnp-6108	209	126	unit	unit	NOUN
fnp-6108	209	127	,	,	PUNCT
fnp-6108	209	128	university	university	PROPN
fnp-6108	209	129	of	of	ADP
fnp-6108	209	130	helsinki	helsinki	PROPN
fnp-6108	209	131	,	,	PUNCT
fnp-6108	209	132	helsinki	helsinki	PROPN
fnp-6108	209	133	,	,	PUNCT
fnp-6108	209	134	finland	finland	PROPN
fnp-6108	209	135	department	department	PROPN
fnp-6108	209	136	of	of	ADP
fnp-6108	209	137	neurology	neurology	NOUN
fnp-6108	209	138	,	,	PUNCT
fnp-6108	209	139	university	university	PROPN
fnp-6108	209	140	of	of	ADP
fnp-6108	209	141	helsinki	helsinki	PROPN
fnp-6108	209	142	and	and	CCONJ
fnp-6108	209	143	helsinki	helsinki	PROPN
fnp-6108	209	144	university	university	PROPN
fnp-6108	209	145	hospital	hospital	NOUN
fnp-6108	209	146	,	,	PUNCT
fnp-6108	209	147	helsinki	helsinki	PROPN
fnp-6108	209	148	,	,	PUNCT
fnp-6108	209	149	finland	finland	PROPN
fnp-6108	209	150	translational	translational	ADJ
fnp-6108	209	151	and	and	CCONJ
fnp-6108	209	152	clinical	clinical	ADJ
fnp-6108	209	153	research	research	PROPN
fnp-6108	209	154	institute	institute	PROPN
fnp-6108	209	155	,	,	PUNCT
fnp-6108	209	156	newcastle	newcastle	PROPN
fnp-6108	209	157	university	university	PROPN
fnp-6108	209	158	,	,	PUNCT
fnp-6108	209	159	newcastle	newcastle	PROPN
fnp-6108	209	160	upon	upon	SCONJ
fnp-6108	209	161	tyne	tyne	PROPN
fnp-6108	209	162	,	,	PUNCT
fnp-6108	209	163	united	united	PROPN
fnp-6108	209	164	kingdom	kingdom	PROPN
fnp-6108	209	165	population	population	NOUN
fnp-6108	209	166	-	-	PUNCT
fnp-6108	209	167	based	base	VERB
fnp-6108	209	168	cohort	cohort	NOUN
fnp-6108	209	169	studies	study	NOUN
fnp-6108	209	170	are	be	AUX
fnp-6108	209	171	essential	essential	ADJ
fnp-6108	209	172	for	for	ADP
fnp-6108	209	173	understanding	understand	VERB
fnp-6108	209	174	the	the	DET
fnp-6108	209	175	pathological	pathological	ADJ
fnp-6108	209	176	basis	basis	NOUN
fnp-6108	209	177	of	of	ADP
fnp-6108	209	178	dementia	dementia	NOUN
fnp-6108	209	179	in	in	ADP
fnp-6108	209	180	older	old	ADJ
fnp-6108	209	181	populations	population	NOUN
fnp-6108	209	182	.	.	PUNCT
fnp-6108	210	1	however	however	ADV
fnp-6108	210	2	,	,	PUNCT
fnp-6108	210	3	few	few	ADJ
fnp-6108	210	4	studies	study	NOUN
fnp-6108	210	5	have	have	AUX
fnp-6108	210	6	examined	examine	VERB
fnp-6108	210	7	limbic	limbic	ADJ
fnp-6108	210	8	-	-	PUNCT
fnp-6108	210	9	predominant	predominant	ADJ
fnp-6108	210	10	age	age	NOUN
fnp-6108	210	11	-	-	PUNCT
fnp-6108	210	12	related	relate	VERB
fnp-6108	210	13	tdp-43	tdp-43	NOUN
fnp-6108	210	14	encephalopathy	encephalopathy	ADJ
fnp-6108	210	15	(	(	PUNCT
fnp-6108	210	16	late	late	PROPN
fnp-6108	210	17	-	-	PUNCT
fnp-6108	210	18	nc	nc	NOUN
fnp-6108	210	19	)	)	PUNCT
fnp-6108	210	20	in	in	ADP
fnp-6108	210	21	a	a	DET
fnp-6108	210	22	population	population	NOUN
fnp-6108	210	23	-	-	PUNCT
fnp-6108	210	24	based	base	VERB
fnp-6108	210	25	setting	setting	NOUN
fnp-6108	210	26	.	.	PUNCT
fnp-6108	211	1	here	here	ADV
fnp-6108	211	2	we	we	PRON
fnp-6108	211	3	investigated	investigate	VERB
fnp-6108	211	4	late	late	ADJ
fnp-6108	211	5	-	-	PUNCT
fnp-6108	211	6	nc	nc	NOUN
fnp-6108	211	7	frequency	frequency	NOUN
fnp-6108	211	8	and	and	CCONJ
fnp-6108	211	9	its	its	PRON
fnp-6108	211	10	associations	association	NOUN
fnp-6108	211	11	with	with	ADP
fnp-6108	211	12	other	other	ADJ
fnp-6108	211	13	brain	brain	NOUN
fnp-6108	211	14	pathologies	pathology	NOUN
fnp-6108	211	15	and	and	CCONJ
fnp-6108	211	16	cognition	cognition	NOUN
fnp-6108	211	17	parameters	parameter	NOUN
fnp-6108	211	18	in	in	ADP
fnp-6108	211	19	a	a	DET
fnp-6108	211	20	population	population	NOUN
fnp-6108	211	21	aged	age	VERB
fnp-6108	211	22	≥	≥	NOUN
fnp-6108	211	23	 	 	SPACE
fnp-6108	211	24	85	85	NUM
fnp-6108	211	25	years	year	NOUN
fnp-6108	211	26	.	.	PUNCT
fnp-6108	212	1	the	the	DET
fnp-6108	212	2	population	population	NOUN
fnp-6108	212	3	-	-	PUNCT
fnp-6108	212	4	based	base	VERB
fnp-6108	212	5	vantaa	vantaa	NOUN
fnp-6108	212	6	 	 	SPACE
fnp-6108	212	7	85	85	NUM
fnp-6108	212	8	+	+	NUM
fnp-6108	212	9	study	study	NOUN
fnp-6108	212	10	includes	include	VERB
fnp-6108	212	11	all	all	DET
fnp-6108	212	12	601	601	NUM
fnp-6108	212	13	individuals	individual	NOUN
fnp-6108	212	14	aged	age	VERB
fnp-6108	212	15	≥	≥	NOUN
fnp-6108	212	16	 	 	SPACE
fnp-6108	212	17	85	85	NUM
fnp-6108	212	18	years	year	NOUN
fnp-6108	212	19	who	who	PRON
fnp-6108	212	20	were	be	AUX
fnp-6108	212	21	living	live	VERB
fnp-6108	212	22	in	in	ADP
fnp-6108	212	23	vantaa	vantaa	PROPN
fnp-6108	212	24	,	,	PUNCT
fnp-6108	212	25	finland	finland	PROPN
fnp-6108	212	26	,	,	PUNCT
fnp-6108	212	27	in	in	ADP
fnp-6108	212	28	1991	1991	NUM
fnp-6108	212	29	.	.	PUNCT
fnp-6108	213	1	neuropathological	neuropathological	ADJ
fnp-6108	213	2	examinations	examination	NOUN
fnp-6108	213	3	were	be	AUX
fnp-6108	213	4	performed	perform	VERB
fnp-6108	213	5	on	on	ADP
fnp-6108	213	6	304	304	NUM
fnp-6108	213	7	subjects	subject	NOUN
fnp-6108	213	8	(	(	PUNCT
fnp-6108	213	9	50.5	50.5	NUM
fnp-6108	213	10	 	 	SPACE
fnp-6108	213	11	%	%	NOUN
fnp-6108	213	12	)	)	PUNCT
fnp-6108	213	13	,	,	PUNCT
fnp-6108	213	14	with	with	ADP
fnp-6108	213	15	late	late	ADJ
fnp-6108	213	16	-	-	PUNCT
fnp-6108	213	17	nc	nc	NOUN
fnp-6108	213	18	staging	staging	NOUN
fnp-6108	213	19	possible	possible	ADJ
fnp-6108	213	20	in	in	ADP
fnp-6108	213	21	295	295	NUM
fnp-6108	213	22	.	.	PUNCT
fnp-6108	214	1	mmse	mmse	ADJ
fnp-6108	214	2	scores	score	NOUN
fnp-6108	214	3	were	be	AUX
fnp-6108	214	4	recorded	record	VERB
fnp-6108	214	5	at	at	ADP
fnp-6108	214	6	baseline	baseline	NOUN
fnp-6108	214	7	and	and	CCONJ
fnp-6108	214	8	in	in	ADP
fnp-6108	214	9	three	three	NUM
fnp-6108	214	10	follow	follow	NOUN
fnp-6108	214	11	-	-	PUNCT
fnp-6108	214	12	ups	up	NOUN
fnp-6108	214	13	(	(	PUNCT
fnp-6108	214	14	1994–99	1994–99	NUM
fnp-6108	214	15	)	)	PUNCT
fnp-6108	214	16	.	.	PUNCT
fnp-6108	215	1	late	late	PROPN
fnp-6108	215	2	-	-	PUNCT
fnp-6108	215	3	nc	nc	PROPN
fnp-6108	215	4	stages	stage	NOUN
fnp-6108	215	5	were	be	AUX
fnp-6108	215	6	determined	determine	VERB
fnp-6108	215	7	using	use	VERB
fnp-6108	215	8	tdp-43	tdp-43	PROPN
fnp-6108	215	9	immunohistochemistry	immunohistochemistry	NOUN
fnp-6108	215	10	.	.	PUNCT
fnp-6108	216	1	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	216	2	was	be	AUX
fnp-6108	216	3	assessed	assess	VERB
fnp-6108	216	4	digitally	digitally	ADV
fnp-6108	216	5	by	by	ADP
fnp-6108	216	6	calculating	calculate	VERB
fnp-6108	216	7	the	the	DET
fnp-6108	216	8	average	average	ADJ
fnp-6108	216	9	sclerotic	sclerotic	ADJ
fnp-6108	216	10	index	index	NOUN
fnp-6108	216	11	of	of	ADP
fnp-6108	216	12	five	five	NUM
fnp-6108	216	13	small	small	ADJ
fnp-6108	216	14	arterioles	arteriole	NOUN
fnp-6108	216	15	in	in	ADP
fnp-6108	216	16	the	the	DET
fnp-6108	216	17	amygdala	amygdala	NOUN
fnp-6108	216	18	,	,	PUNCT
fnp-6108	216	19	hippocampus	hippocampus	NOUN
fnp-6108	216	20	,	,	PUNCT
fnp-6108	216	21	and	and	CCONJ
fnp-6108	216	22	frontal	frontal	ADJ
fnp-6108	216	23	white	white	ADJ
fnp-6108	216	24	matter	matter	NOUN
fnp-6108	216	25	.	.	PUNCT
fnp-6108	217	1	associations	association	NOUN
fnp-6108	217	2	of	of	ADP
fnp-6108	217	3	late	late	PROPN
fnp-6108	217	4	-	-	PUNCT
fnp-6108	217	5	nc	nc	NOUN
fnp-6108	217	6	with	with	ADP
fnp-6108	217	7	previously	previously	ADV
fnp-6108	217	8	determined	determine	VERB
fnp-6108	217	9	neuropathological	neuropathological	ADJ
fnp-6108	217	10	variables	variable	NOUN
fnp-6108	217	11	such	such	ADJ
fnp-6108	217	12	as	as	ADP
fnp-6108	217	13	alzheimer	alzheimer	PROPN
fnp-6108	217	14	’s	’s	PART
fnp-6108	217	15	disease	disease	NOUN
fnp-6108	217	16	neuropathological	neuropathological	ADJ
fnp-6108	217	17	change	change	NOUN
fnp-6108	217	18	(	(	PUNCT
fnp-6108	217	19	adnc	adnc	ADJ
fnp-6108	217	20	)	)	PUNCT
fnp-6108	217	21	,	,	PUNCT
fnp-6108	217	22	lewy	lewy	PROPN
fnp-6108	217	23	-	-	PUNCT
fnp-6108	217	24	related	relate	VERB
fnp-6108	217	25	pathology	pathology	NOUN
fnp-6108	217	26	(	(	PUNCT
fnp-6108	217	27	lrp	lrp	PROPN
fnp-6108	217	28	)	)	PUNCT
fnp-6108	217	29	,	,	PUNCT
fnp-6108	217	30	hippocampal	hippocampal	ADJ
fnp-6108	217	31	sclerosis	sclerosis	NOUN
fnp-6108	217	32	(	(	PUNCT
fnp-6108	217	33	hs	hs	PROPN
fnp-6108	217	34	)	)	PUNCT
fnp-6108	217	35	,	,	PUNCT
fnp-6108	217	36	cerebral	cerebral	ADJ
fnp-6108	217	37	amyloid	amyloid	NOUN
fnp-6108	217	38	angiopathy	angiopathy	ADJ
fnp-6108	217	39	(	(	PUNCT
fnp-6108	217	40	caa	caa	NOUN
fnp-6108	217	41	)	)	PUNCT
fnp-6108	217	42	,	,	PUNCT
fnp-6108	217	43	and	and	CCONJ
fnp-6108	217	44	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	217	45	,	,	PUNCT
fnp-6108	217	46	as	as	ADV
fnp-6108	217	47	well	well	ADV
fnp-6108	217	48	as	as	ADP
fnp-6108	217	49	cognitive	cognitive	ADJ
fnp-6108	217	50	variables	variable	NOUN
fnp-6108	217	51	were	be	AUX
fnp-6108	217	52	analyzed	analyze	VERB
fnp-6108	217	53	using	use	VERB
fnp-6108	217	54	fisher	fisher	PROPN
fnp-6108	217	55	’s	’s	PART
fnp-6108	217	56	exact	exact	ADJ
fnp-6108	217	57	test	test	NOUN
fnp-6108	217	58	and	and	CCONJ
fnp-6108	217	59	regression	regression	NOUN
fnp-6108	217	60	models	model	NOUN
fnp-6108	217	61	.	.	PUNCT
fnp-6108	218	1	late	late	PROPN
fnp-6108	218	2	-	-	PUNCT
fnp-6108	218	3	nc	nc	PROPN
fnp-6108	218	4	was	be	AUX
fnp-6108	218	5	found	find	VERB
fnp-6108	218	6	in	in	ADP
fnp-6108	218	7	64.1	64.1	NUM
fnp-6108	218	8	 	 	SPACE
fnp-6108	218	9	%	%	NOUN
fnp-6108	218	10	of	of	ADP
fnp-6108	218	11	subjects	subject	NOUN
fnp-6108	218	12	,	,	PUNCT
fnp-6108	218	13	with	with	ADP
fnp-6108	218	14	stage	stage	NOUN
fnp-6108	218	15	2	2	NUM
fnp-6108	218	16	being	be	AUX
fnp-6108	218	17	the	the	DET
fnp-6108	218	18	most	most	ADV
fnp-6108	218	19	common	common	ADJ
fnp-6108	218	20	(	(	PUNCT
fnp-6108	218	21	28.5	28.5	NUM
fnp-6108	218	22	 	 	SPACE
fnp-6108	218	23	%	%	NOUN
fnp-6108	218	24	)	)	PUNCT
fnp-6108	218	25	.	.	PUNCT
fnp-6108	219	1	stages	stage	NOUN
fnp-6108	219	2	1a	1a	NOUN
fnp-6108	219	3	,	,	PUNCT
fnp-6108	219	4	2	2	NUM
fnp-6108	219	5	,	,	PUNCT
fnp-6108	219	6	and	and	CCONJ
fnp-6108	219	7	3	3	NUM
fnp-6108	219	8	were	be	AUX
fnp-6108	219	9	significantly	significantly	ADV
fnp-6108	219	10	associated	associate	VERB
fnp-6108	219	11	with	with	ADP
fnp-6108	219	12	dementia	dementia	NOUN
fnp-6108	219	13	and	and	CCONJ
fnp-6108	219	14	lower	low	ADJ
fnp-6108	219	15	mmse	mmse	ADJ
fnp-6108	219	16	scores	score	NOUN
fnp-6108	219	17	.	.	PUNCT
fnp-6108	220	1	late	late	PROPN
fnp-6108	220	2	-	-	PUNCT
fnp-6108	220	3	nc	nc	PROPN
fnp-6108	220	4	was	be	AUX
fnp-6108	220	5	significantly	significantly	ADV
fnp-6108	220	6	associated	associate	VERB
fnp-6108	220	7	with	with	ADP
fnp-6108	220	8	adnc	adnc	ADJ
fnp-6108	220	9	,	,	PUNCT
fnp-6108	220	10	hs	hs	PROPN
fnp-6108	220	11	,	,	PUNCT
fnp-6108	220	12	diffuse	diffuse	ADJ
fnp-6108	220	13	neocortical	neocortical	ADJ
fnp-6108	220	14	lrp	lrp	NOUN
fnp-6108	220	15	,	,	PUNCT
fnp-6108	220	16	and	and	CCONJ
fnp-6108	220	17	amygdala	amygdala	NOUN
fnp-6108	220	18	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	220	19	.	.	PUNCT
fnp-6108	221	1	in	in	ADP
fnp-6108	221	2	most	most	ADJ
fnp-6108	221	3	cases	case	NOUN
fnp-6108	221	4	late	late	ADJ
fnp-6108	221	5	-	-	PUNCT
fnp-6108	221	6	nc	nc	NOUN
fnp-6108	221	7	co	co	NOUN
fnp-6108	221	8	-	-	VERB
fnp-6108	221	9	occurred	occur	VERB
fnp-6108	221	10	with	with	ADP
fnp-6108	221	11	other	other	ADJ
fnp-6108	221	12	neuropathological	neuropathological	ADJ
fnp-6108	221	13	changes	change	NOUN
fnp-6108	221	14	.	.	PUNCT
fnp-6108	222	1	in	in	ADP
fnp-6108	222	2	all	all	DET
fnp-6108	222	3	multivariate	multivariate	NOUN
fnp-6108	222	4	models	model	NOUN
fnp-6108	222	5	late	late	ADJ
fnp-6108	222	6	-	-	PUNCT
fnp-6108	222	7	nc	nc	PROPN
fnp-6108	222	8	was	be	AUX
fnp-6108	222	9	among	among	ADP
fnp-6108	222	10	the	the	DET
fnp-6108	222	11	strongest	strong	ADJ
fnp-6108	222	12	independent	independent	ADJ
fnp-6108	222	13	predictors	predictor	NOUN
fnp-6108	222	14	of	of	ADP
fnp-6108	222	15	dementia	dementia	NOUN
fnp-6108	222	16	.	.	PUNCT
fnp-6108	223	1	this	this	DET
fnp-6108	223	2	study	study	NOUN
fnp-6108	223	3	provides	provide	VERB
fnp-6108	223	4	evidence	evidence	NOUN
fnp-6108	223	5	that	that	SCONJ
fnp-6108	223	6	late	late	ADJ
fnp-6108	223	7	-	-	PUNCT
fnp-6108	223	8	nc	nc	PROPN
fnp-6108	223	9	is	be	AUX
fnp-6108	223	10	common	common	ADJ
fnp-6108	223	11	and	and	CCONJ
fnp-6108	223	12	a	a	DET
fnp-6108	223	13	significant	significant	ADJ
fnp-6108	223	14	determinant	determinant	NOUN
fnp-6108	223	15	of	of	ADP
fnp-6108	223	16	dementia	dementia	NOUN
fnp-6108	223	17	in	in	ADP
fnp-6108	223	18	the	the	DET
fnp-6108	223	19	very	very	ADV
fnp-6108	223	20	elderly	elderly	ADJ
fnp-6108	223	21	population	population	NOUN
fnp-6108	223	22	.	.	PUNCT
fnp-6108	223	23	  	  	SPACE
fnp-6108	224	1	free	free	ADJ
fnp-6108	224	2	neuropathol	neuropathol	NOUN
fnp-6108	224	3	5:30:24	5:30:24	NUM
fnp-6108	224	4	glial	glial	ADJ
fnp-6108	224	5	activation	activation	NOUN
fnp-6108	224	6	and	and	CCONJ
fnp-6108	224	7	tdp-43	tdp-43	NOUN
fnp-6108	224	8	differences	difference	NOUN
fnp-6108	224	9	among	among	ADP
fnp-6108	224	10	neuropathologic	neuropathologic	ADJ
fnp-6108	224	11	subtypes	subtype	NOUN
fnp-6108	224	12	of	of	ADP
fnp-6108	224	13	alzheimer	alzheimer	PROPN
fnp-6108	224	14	’s	’s	PART
fnp-6108	224	15	disease	disease	NOUN
fnp-6108	224	16	sara	sara	PROPN
fnp-6108	224	17	r.	r.	PROPN
fnp-6108	224	18	dunlop1	dunlop1	PROPN
fnp-6108	224	19	,	,	PUNCT
fnp-6108	224	20	zhongwei	zhongwei	PROPN
fnp-6108	224	21	peng2	peng2	PROPN
fnp-6108	224	22	,	,	PUNCT
fnp-6108	224	23	baayla	baayla	PROPN
fnp-6108	224	24	d.c	d.c	PROPN
fnp-6108	224	25	.	.	PUNCT
fnp-6108	224	26	boon1	boon1	PROPN
fnp-6108	224	27	,	,	PUNCT
fnp-6108	224	28	christina	christina	PROPN
fnp-6108	224	29	m.	m.	PROPN
fnp-6108	224	30	moloney1	moloney1	PROPN
fnp-6108	224	31	,	,	PUNCT
fnp-6108	224	32	isabelle	isabelle	PROPN
fnp-6108	224	33	frankenhauser1,5	frankenhauser1,5	PROPN
fnp-6108	224	34	,	,	PUNCT
fnp-6108	224	35	sydney	sydney	PROPN
fnp-6108	224	36	a.	a.	PROPN
fnp-6108	224	37	labuzan1	labuzan1	PROPN
fnp-6108	224	38	,	,	PUNCT
fnp-6108	224	39	cyril	cyril	PROPN
fnp-6108	224	40	pottier1	pottier1	PROPN
fnp-6108	224	41	,	,	PUNCT
fnp-6108	224	42	daniel	daniel	PROPN
fnp-6108	224	43	p.	p.	PROPN
fnp-6108	224	44	wickland2	wickland2	PROPN
fnp-6108	224	45	,	,	PUNCT
fnp-6108	224	46	kelsey	kelsey	PROPN
fnp-6108	224	47	caetano	caetano	PROPN
fnp-6108	224	48	-	-	PUNCT
fnp-6108	224	49	anolles1	anolles1	PROPN
fnp-6108	224	50	,	,	PUNCT
fnp-6108	224	51	jessica	jessica	PROPN
fnp-6108	224	52	f.	f.	PROPN
fnp-6108	224	53	tranovich1	tranovich1	PROPN
fnp-6108	224	54	,	,	PUNCT
fnp-6108	224	55	ashley	ashley	PROPN
fnp-6108	224	56	c.	c.	PROPN
fnp-6108	224	57	wood1	wood1	PROPN
fnp-6108	224	58	,	,	PUNCT
fnp-6108	224	59	kelly	kelly	PROPN
fnp-6108	224	60	m.	m.	PROPN
fnp-6108	224	61	hinkle1	hinkle1	PROPN
fnp-6108	224	62	,	,	PUNCT
fnp-6108	224	63	sarah	sarah	PROPN
fnp-6108	224	64	j.	j.	PROPN
fnp-6108	224	65	lincoln1	lincoln1	PROPN
fnp-6108	224	66	,	,	PUNCT
fnp-6108	224	67	rain	rain	NOUN
fnp-6108	224	68	s.	s.	PROPN
fnp-6108	224	69	kwan2	kwan2	PROPN
fnp-6108	224	70	,	,	PUNCT
fnp-6108	224	71	owen	owen	PROPN
fnp-6108	224	72	a.	a.	PROPN
fnp-6108	224	73	ross1	ross1	PROPN
fnp-6108	224	74	,	,	PUNCT
fnp-6108	224	75	christian	christian	PROPN
fnp-6108	224	76	lachner3,4	lachner3,4	PROPN
fnp-6108	224	77	,	,	PUNCT
fnp-6108	224	78	nilüfer	nilüfer	VERB
fnp-6108	224	79	ertekin	ertekin	PROPN
fnp-6108	224	80	-	-	PUNCT
fnp-6108	224	81	taner1,4	taner1,4	PROPN
fnp-6108	224	82	,	,	PUNCT
fnp-6108	224	83	gregory	gregory	PROPN
fnp-6108	224	84	s.	s.	PROPN
fnp-6108	224	85	day4	day4	PROPN
fnp-6108	224	86	,	,	PUNCT
fnp-6108	224	87	ranjan	ranjan	PROPN
fnp-6108	224	88	duara6	duara6	PROPN
fnp-6108	224	89	,	,	PUNCT
fnp-6108	224	90	neill	neill	PROPN
fnp-6108	224	91	r.	r.	PROPN
fnp-6108	224	92	graff	graff	PROPN
fnp-6108	224	93	-	-	PUNCT
fnp-6108	224	94	radford4	radford4	NOUN
fnp-6108	224	95	,	,	PUNCT
fnp-6108	224	96	dennis	dennis	PROPN
fnp-6108	224	97	w.	w.	PROPN
fnp-6108	224	98	dickson1	dickson1	PROPN
fnp-6108	224	99	,	,	PUNCT
fnp-6108	224	100	rickey	rickey	PROPN
fnp-6108	224	101	e.	e.	PROPN
fnp-6108	224	102	carter2	carter2	PROPN
fnp-6108	224	103	,	,	PUNCT
fnp-6108	225	1	melissa	melissa	PROPN
fnp-6108	225	2	e.	e.	PROPN
fnp-6108	225	3	murray1	murray1	PROPN
fnp-6108	225	4	department	department	PROPN
fnp-6108	225	5	of	of	ADP
fnp-6108	225	6	neuroscience	neuroscience	NOUN
fnp-6108	225	7	,	,	PUNCT
fnp-6108	225	8	mayo	mayo	NOUN
fnp-6108	225	9	clinic	clinic	PROPN
fnp-6108	225	10	,	,	PUNCT
fnp-6108	225	11	jacksonville	jacksonville	PROPN
fnp-6108	225	12	,	,	PUNCT
fnp-6108	225	13	fl	fl	PROPN
fnp-6108	225	14	,	,	PUNCT
fnp-6108	225	15	usa	usa	PROPN
fnp-6108	225	16	department	department	PROPN
fnp-6108	225	17	of	of	ADP
fnp-6108	225	18	quantitative	quantitative	ADJ
fnp-6108	225	19	health	health	NOUN
fnp-6108	225	20	sciences	science	NOUN
fnp-6108	225	21	,	,	PUNCT
fnp-6108	225	22	mayo	mayo	NOUN
fnp-6108	225	23	clinic	clinic	PROPN
fnp-6108	225	24	,	,	PUNCT
fnp-6108	225	25	jacksonville	jacksonville	PROPN
fnp-6108	225	26	,	,	PUNCT
fnp-6108	225	27	fl	fl	PROPN
fnp-6108	225	28	,	,	PUNCT
fnp-6108	225	29	usa	usa	PROPN
fnp-6108	225	30	department	department	PROPN
fnp-6108	225	31	of	of	ADP
fnp-6108	225	32	psychiatry	psychiatry	NOUN
fnp-6108	225	33	and	and	CCONJ
fnp-6108	225	34	psychology	psychology	NOUN
fnp-6108	225	35	,	,	PUNCT
fnp-6108	225	36	mayo	mayo	NOUN
fnp-6108	225	37	clinic	clinic	PROPN
fnp-6108	225	38	,	,	PUNCT
fnp-6108	225	39	jacksonville	jacksonville	PROPN
fnp-6108	225	40	,	,	PUNCT
fnp-6108	225	41	fl	fl	PROPN
fnp-6108	225	42	,	,	PUNCT
fnp-6108	225	43	usa	usa	PROPN
fnp-6108	225	44	department	department	PROPN
fnp-6108	225	45	of	of	ADP
fnp-6108	225	46	neurology	neurology	NOUN
fnp-6108	225	47	,	,	PUNCT
fnp-6108	225	48	mayo	mayo	NOUN
fnp-6108	225	49	clinic	clinic	PROPN
fnp-6108	225	50	,	,	PUNCT
fnp-6108	225	51	jacksonville	jacksonville	PROPN
fnp-6108	225	52	,	,	PUNCT
fnp-6108	225	53	fl	fl	PROPN
fnp-6108	225	54	,	,	PUNCT
fnp-6108	225	55	usa	usa	PROPN
fnp-6108	225	56	paracelsus	paracelsus	PROPN
fnp-6108	225	57	medical	medical	PROPN
fnp-6108	225	58	private	private	PROPN
fnp-6108	225	59	university	university	PROPN
fnp-6108	225	60	,	,	PUNCT
fnp-6108	225	61	salzburg	salzburg	PROPN
fnp-6108	225	62	,	,	PUNCT
fnp-6108	225	63	austria	austria	PROPN
fnp-6108	225	64	wien	wien	PROPN
fnp-6108	225	65	center	center	PROPN
fnp-6108	225	66	for	for	ADP
fnp-6108	225	67	alzheimer	alzheimer	PROPN
fnp-6108	225	68	’s	’s	PART
fnp-6108	225	69	disease	disease	NOUN
fnp-6108	225	70	and	and	CCONJ
fnp-6108	225	71	memory	memory	NOUN
fnp-6108	225	72	disorders	disorder	NOUN
fnp-6108	225	73	,	,	PUNCT
fnp-6108	225	74	mount	mount	PROPN
fnp-6108	225	75	sinai	sinai	PROPN
fnp-6108	225	76	medical	medical	PROPN
fnp-6108	225	77	center	center	PROPN
fnp-6108	225	78	,	,	PUNCT
fnp-6108	225	79	miami	miami	PROPN
fnp-6108	225	80	beach	beach	PROPN
fnp-6108	225	81	,	,	PUNCT
fnp-6108	225	82	fl	fl	PROPN
fnp-6108	225	83	,	,	PUNCT
fnp-6108	225	84	usa	usa	PROPN
fnp-6108	225	85	selective	selective	ADJ
fnp-6108	225	86	corticolimbic	corticolimbic	NOUN
fnp-6108	225	87	vulnerability	vulnerability	NOUN
fnp-6108	225	88	to	to	ADP
fnp-6108	225	89	tau	tau	PROPN
fnp-6108	225	90	pathology	pathology	PROPN
fnp-6108	225	91	in	in	ADP
fnp-6108	225	92	alzheimer	alzheimer	PROPN
fnp-6108	225	93	’s	’s	PART
fnp-6108	225	94	disease	disease	NOUN
fnp-6108	225	95	(	(	PUNCT
fnp-6108	225	96	ad	ad	NOUN
fnp-6108	225	97	)	)	PUNCT
fnp-6108	225	98	underlies	underlie	VERB
fnp-6108	225	99	clinicopathologic	clinicopathologic	ADJ
fnp-6108	225	100	heterogeneity	heterogeneity	NOUN
fnp-6108	225	101	.	.	PUNCT
fnp-6108	226	1	we	we	PRON
fnp-6108	226	2	aimed	aim	VERB
fnp-6108	226	3	to	to	PART
fnp-6108	226	4	re	re	VERB
fnp-6108	226	5	-	-	VERB
fnp-6108	226	6	express	express	VERB
fnp-6108	226	7	the	the	DET
fnp-6108	226	8	ad	ad	NOUN
fnp-6108	226	9	subtype	subtype	NOUN
fnp-6108	226	10	algorithm	algorithm	NOUN
fnp-6108	226	11	as	as	ADP
fnp-6108	226	12	a	a	DET
fnp-6108	226	13	corticolimbic	corticolimbic	NOUN
fnp-6108	226	14	index	index	NOUN
fnp-6108	226	15	(	(	PUNCT
fnp-6108	226	16	clix	clix	NOUN
fnp-6108	226	17	)	)	PUNCT
fnp-6108	226	18	to	to	PART
fnp-6108	226	19	quantitatively	quantitatively	ADV
fnp-6108	226	20	examine	examine	VERB
fnp-6108	226	21	heterogeneity	heterogeneity	NOUN
fnp-6108	226	22	and	and	CCONJ
fnp-6108	226	23	deeply	deeply	ADV
fnp-6108	226	24	phenotype	phenotype	NOUN
fnp-6108	226	25	corticolimbic	corticolimbic	NOUN
fnp-6108	226	26	patterns	pattern	NOUN
fnp-6108	226	27	of	of	ADP
fnp-6108	226	28	ad	ad	NOUN
fnp-6108	226	29	pathology	pathology	NOUN
fnp-6108	226	30	and	and	CCONJ
fnp-6108	226	31	glial	glial	ADJ
fnp-6108	226	32	activation	activation	NOUN
fnp-6108	226	33	in	in	ADP
fnp-6108	226	34	neuropathologically	neuropathologically	ADV
fnp-6108	226	35	diagnosed	diagnose	VERB
fnp-6108	226	36	ad	ad	NOUN
fnp-6108	226	37	.	.	PUNCT
fnp-6108	227	1	clix	clix	PROPN
fnp-6108	227	2	was	be	AUX
fnp-6108	227	3	developed	develop	VERB
fnp-6108	227	4	(	(	PUNCT
fnp-6108	227	5	n	n	CCONJ
fnp-6108	227	6	 	 	SPACE
fnp-6108	227	7	=	=	NOUN
fnp-6108	227	8	 	 	SPACE
fnp-6108	227	9	1361	1361	NUM
fnp-6108	227	10	ad	ad	NOUN
fnp-6108	227	11	)	)	PUNCT
fnp-6108	227	12	to	to	PART
fnp-6108	227	13	collapse	collapse	VERB
fnp-6108	227	14	spatial	spatial	ADJ
fnp-6108	227	15	distribution	distribution	NOUN
fnp-6108	227	16	of	of	ADP
fnp-6108	227	17	thioflavin	thioflavin	PROPN
fnp-6108	227	18	-	-	PUNCT
fnp-6108	227	19	s	s	NOUN
fnp-6108	227	20	tangle	tangle	NOUN
fnp-6108	227	21	counts	count	NOUN
fnp-6108	227	22	to	to	PART
fnp-6108	227	23	assign	assign	VERB
fnp-6108	227	24	a	a	DET
fnp-6108	227	25	continuum	continuum	ADJ
fnp-6108	227	26	:	:	PUNCT
fnp-6108	227	27	hippocampal	hippocampal	NOUN
fnp-6108	227	28	sparing	sparing	NOUN
fnp-6108	227	29	(	(	PUNCT
fnp-6108	227	30	<	<	X
fnp-6108	227	31	 	 	SPACE
fnp-6108	227	32	10	10	NUM
fnp-6108	227	33	)	)	PUNCT
fnp-6108	227	34	,	,	PUNCT
fnp-6108	227	35	representative	representative	NOUN
fnp-6108	227	36	/	/	SYM
fnp-6108	227	37	typical	typical	ADJ
fnp-6108	227	38	(	(	PUNCT
fnp-6108	227	39	≥	≥	NOUN
fnp-6108	227	40	 	 	SPACE
fnp-6108	227	41	10	10	NUM
fnp-6108	227	42	to	to	PART
fnp-6108	227	43	<	<	NOUN
fnp-6108	227	44	 	 	SPACE
fnp-6108	227	45	30	30	NUM
fnp-6108	227	46	)	)	PUNCT
fnp-6108	227	47	,	,	PUNCT
fnp-6108	227	48	and	and	CCONJ
fnp-6108	227	49	limbic	limbic	ADJ
fnp-6108	227	50	predominant	predominant	ADJ
fnp-6108	227	51	(	(	PUNCT
fnp-6108	227	52	≥	≥	NOUN
fnp-6108	227	53	 	 	SPACE
fnp-6108	227	54	30	30	NUM
fnp-6108	227	55	)	)	PUNCT
fnp-6108	227	56	.	.	PUNCT
fnp-6108	228	1	presence	presence	NOUN
fnp-6108	228	2	of	of	ADP
fnp-6108	228	3	atypical	atypical	ADJ
fnp-6108	228	4	,	,	PUNCT
fnp-6108	228	5	non	non	ADJ
fnp-6108	228	6	-	-	ADJ
fnp-6108	228	7	amnestic	amnestic	ADJ
fnp-6108	228	8	clinical	clinical	ADJ
fnp-6108	228	9	presentation	presentation	NOUN
fnp-6108	228	10	and	and	CCONJ
fnp-6108	228	11	clinical	clinical	ADJ
fnp-6108	228	12	progression	progression	NOUN
fnp-6108	228	13	on	on	ADP
fnp-6108	228	14	mmse	mmse	ADJ
fnp-6108	228	15	were	be	AUX
fnp-6108	228	16	investigated	investigate	VERB
fnp-6108	228	17	.	.	PUNCT
fnp-6108	229	1	digital	digital	ADJ
fnp-6108	229	2	pathology	pathology	NOUN
fnp-6108	229	3	measures	measure	NOUN
fnp-6108	229	4	of	of	ADP
fnp-6108	229	5	ad	ad	NOUN
fnp-6108	229	6	(	(	PUNCT
fnp-6108	229	7	tau	tau	PROPN
fnp-6108	230	1	[	[	X
fnp-6108	230	2	at8	at8	PROPN
fnp-6108	230	3	,	,	PUNCT
fnp-6108	230	4	gt-38	gt-38	X
fnp-6108	230	5	]	]	X
fnp-6108	230	6	,	,	PUNCT
fnp-6108	230	7	amyloid	amyloid	NOUN
fnp-6108	230	8	-	-	PUNCT
fnp-6108	230	9	β	β	NOUN
fnp-6108	231	1	[	[	X
fnp-6108	231	2	6f/3d	6f/3d	NUM
fnp-6108	231	3	]	]	PUNCT
fnp-6108	231	4	)	)	PUNCT
fnp-6108	231	5	were	be	AUX
fnp-6108	231	6	performed	perform	VERB
fnp-6108	231	7	in	in	ADP
fnp-6108	231	8	hippocampus	hippocampus	NOUN
fnp-6108	231	9	and	and	CCONJ
fnp-6108	231	10	association	association	NOUN
fnp-6108	231	11	cortices	cortex	NOUN
fnp-6108	231	12	(	(	PUNCT
fnp-6108	231	13	n	n	CCONJ
fnp-6108	231	14	 	 	SPACE
fnp-6108	231	15	=	=	NOUN
fnp-6108	231	16	 	 	SPACE
fnp-6108	231	17	60	60	NUM
fnp-6108	231	18	)	)	PUNCT
fnp-6108	231	19	,	,	PUNCT
fnp-6108	231	20	which	which	PRON
fnp-6108	231	21	were	be	AUX
fnp-6108	231	22	modeled	model	VERB
fnp-6108	231	23	with	with	ADP
fnp-6108	231	24	late	late	ADJ
fnp-6108	231	25	-	-	PUNCT
fnp-6108	231	26	tdp-43	tdp-43	NOUN
fnp-6108	231	27	staging	staging	NOUN
fnp-6108	231	28	to	to	PART
fnp-6108	231	29	predict	predict	VERB
fnp-6108	231	30	glial	glial	ADJ
fnp-6108	231	31	activation	activation	NOUN
fnp-6108	231	32	burden	burden	NOUN
fnp-6108	231	33	(	(	PUNCT
fnp-6108	231	34	astroglial	astroglial	ADJ
fnp-6108	231	35	:	:	PUNCT
fnp-6108	231	36	gfap	gfap	ADJ
fnp-6108	231	37	,	,	PUNCT
fnp-6108	231	38	microglial	microglial	ADJ
fnp-6108	231	39	/	/	SYM
fnp-6108	231	40	macrophage	macrophage	NOUN
fnp-6108	231	41	:	:	PUNCT
fnp-6108	231	42	cd68	cd68	PROPN
fnp-6108	231	43	)	)	PUNCT
fnp-6108	231	44	.	.	PUNCT
fnp-6108	232	1	lower	low	ADJ
fnp-6108	232	2	clix	clix	ADJ
fnp-6108	232	3	score	score	NOUN
fnp-6108	232	4	correlated	correlate	VERB
fnp-6108	232	5	with	with	ADP
fnp-6108	232	6	younger	young	ADJ
fnp-6108	232	7	age	age	NOUN
fnp-6108	232	8	at	at	ADP
fnp-6108	232	9	onset	onset	NOUN
fnp-6108	232	10	(	(	PUNCT
fnp-6108	232	11	r	r	NOUN
fnp-6108	232	12	 	 	SPACE
fnp-6108	232	13	=	=	NOUN
fnp-6108	232	14	 	 	SPACE
fnp-6108	232	15	0.39	0.39	NUM
fnp-6108	232	16	,	,	PUNCT
fnp-6108	232	17	p	p	X
fnp-6108	232	18	 	 	SPACE
fnp-6108	232	19	<	<	X
fnp-6108	232	20	 	 	SPACE
fnp-6108	232	21	0.001	0.001	NUM
fnp-6108	232	22	)	)	PUNCT
fnp-6108	232	23	,	,	PUNCT
fnp-6108	232	24	faster	fast	ADV
fnp-6108	232	25	mmse	mmse	ADJ
fnp-6108	232	26	decline	decline	NOUN
fnp-6108	232	27	(	(	PUNCT
fnp-6108	232	28	r	r	NOUN
fnp-6108	232	29	 	 	SPACE
fnp-6108	232	30	=	=	NOUN
fnp-6108	232	31	 	 	SPACE
fnp-6108	232	32	0.27	0.27	NUM
fnp-6108	232	33	,	,	PUNCT
fnp-6108	232	34	p	p	X
fnp-6108	232	35	 	 	SPACE
fnp-6108	232	36	<	<	X
fnp-6108	232	37	 	 	SPACE
fnp-6108	232	38	0.001	0.001	NUM
fnp-6108	232	39	)	)	PUNCT
fnp-6108	232	40	,	,	PUNCT
fnp-6108	232	41	and	and	CCONJ
fnp-6108	232	42	associated	associate	VERB
fnp-6108	232	43	with	with	ADP
fnp-6108	232	44	non	non	ADJ
fnp-6108	232	45	-	-	ADJ
fnp-6108	232	46	amnestic	amnestic	ADJ
fnp-6108	232	47	clinical	clinical	ADJ
fnp-6108	232	48	presentations	presentation	NOUN
fnp-6108	232	49	(	(	PUNCT
fnp-6108	232	50	median	median	NOUN
fnp-6108	232	51	 	 	SPACE
fnp-6108	232	52	=	=	NOUN
fnp-6108	232	53	 	 	SPACE
fnp-6108	232	54	13	13	NUM
fnp-6108	232	55	vs.	vs.	ADP
fnp-6108	232	56	21	21	NUM
fnp-6108	232	57	,	,	PUNCT
fnp-6108	232	58	p	p	X
fnp-6108	232	59	 	 	SPACE
fnp-6108	232	60	<	<	X
fnp-6108	232	61	 	 	SPACE
fnp-6108	232	62	0.001	0.001	NUM
fnp-6108	232	63	)	)	PUNCT
fnp-6108	232	64	.	.	PUNCT
fnp-6108	233	1	advanced	advanced	ADJ
fnp-6108	233	2	tangle	tangle	NOUN
fnp-6108	233	3	maturity	maturity	NOUN
fnp-6108	233	4	burden	burden	NOUN
fnp-6108	233	5	(	(	PUNCT
fnp-6108	233	6	gt-38	gt-38	NOUN
fnp-6108	233	7	)	)	PUNCT
fnp-6108	233	8	differed	differ	VERB
fnp-6108	233	9	across	across	ADP
fnp-6108	233	10	all	all	DET
fnp-6108	233	11	regions	region	NOUN
fnp-6108	233	12	(	(	PUNCT
fnp-6108	233	13	p	p	X
fnp-6108	233	14	 	 	SPACE
fnp-6108	233	15	<	<	X
fnp-6108	233	16	 	 	SPACE
fnp-6108	233	17	0.001	0.001	NUM
fnp-6108	233	18	)	)	PUNCT
fnp-6108	233	19	.	.	PUNCT
fnp-6108	234	1	hippocampal	hippocampal	ADJ
fnp-6108	234	2	sparing	spare	VERB
fnp-6108	234	3	ad	ad	NOUN
fnp-6108	234	4	exhibited	exhibit	VERB
fnp-6108	234	5	higher	high	ADJ
fnp-6108	234	6	cortical	cortical	ADJ
fnp-6108	234	7	tau	tau	NOUN
fnp-6108	234	8	pathology	pathology	NOUN
fnp-6108	234	9	and	and	CCONJ
fnp-6108	234	10	reduced	reduce	VERB
fnp-6108	234	11	cortical	cortical	ADJ
fnp-6108	234	12	cd68	cd68	PROPN
fnp-6108	234	13	.	.	PUNCT
fnp-6108	235	1	regression	regression	NOUN
fnp-6108	235	2	modeling	modeling	NOUN
fnp-6108	235	3	of	of	ADP
fnp-6108	235	4	glial	glial	ADJ
fnp-6108	235	5	activation	activation	NOUN
fnp-6108	235	6	(	(	PUNCT
fnp-6108	235	7	gfap	gfap	NOUN
fnp-6108	235	8	[	[	X
fnp-6108	235	9	r2	r2	NOUN
fnp-6108	235	10	 	 	SPACE
fnp-6108	235	11	=	=	NOUN
fnp-6108	235	12	 	 	SPACE
fnp-6108	235	13	0.21–0.56	0.21–0.56	NUM
fnp-6108	235	14	]	]	PUNCT
fnp-6108	235	15	,	,	PUNCT
fnp-6108	235	16	cd68	cd68	PROPN
fnp-6108	235	17	[	[	X
fnp-6108	235	18	r2	r2	PROPN
fnp-6108	235	19	 	 	SPACE
fnp-6108	235	20	=	=	NOUN
fnp-6108	235	21	 	 	SPACE
fnp-6108	235	22	0.23–0.60	0.23–0.60	NUM
fnp-6108	235	23	]	]	PUNCT
fnp-6108	235	24	)	)	PUNCT
fnp-6108	235	25	found	find	VERB
fnp-6108	235	26	tau	tau	PROPN
fnp-6108	235	27	and	and	CCONJ
fnp-6108	235	28	amyloid	amyloid	NOUN
fnp-6108	235	29	-	-	PUNCT
fnp-6108	235	30	β	β	PRON
fnp-6108	235	31	similarly	similarly	ADV
fnp-6108	235	32	associated	associate	VERB
fnp-6108	235	33	with	with	ADP
fnp-6108	235	34	gfap	gfap	NOUN
fnp-6108	235	35	and	and	CCONJ
fnp-6108	235	36	cd68	cd68	PROPN
fnp-6108	235	37	,	,	PUNCT
fnp-6108	235	38	but	but	CCONJ
fnp-6108	235	39	tdp-43	tdp-43	NOUN
fnp-6108	235	40	stage	stage	NOUN
fnp-6108	235	41	associated	associate	VERB
fnp-6108	235	42	with	with	ADP
fnp-6108	235	43	the	the	DET
fnp-6108	235	44	greatest	great	ADJ
fnp-6108	235	45	glial	glial	ADJ
fnp-6108	235	46	change	change	NOUN
fnp-6108	235	47	.	.	PUNCT
fnp-6108	236	1	corticolimbic	corticolimbic	NOUN
fnp-6108	236	2	tangle	tangle	NOUN
fnp-6108	236	3	distribution	distribution	NOUN
fnp-6108	236	4	is	be	AUX
fnp-6108	236	5	correlated	correlate	VERB
fnp-6108	236	6	with	with	ADP
fnp-6108	236	7	ad	ad	NOUN
fnp-6108	236	8	clinical	clinical	ADJ
fnp-6108	236	9	phenotype	phenotype	NOUN
fnp-6108	236	10	and	and	CCONJ
fnp-6108	236	11	progression	progression	NOUN
fnp-6108	236	12	.	.	PUNCT
fnp-6108	237	1	reduced	reduce	VERB
fnp-6108	237	2	cd68	cd68	PROPN
fnp-6108	237	3	in	in	ADP
fnp-6108	237	4	association	association	NOUN
fnp-6108	237	5	cortices	cortex	NOUN
fnp-6108	237	6	of	of	ADP
fnp-6108	237	7	cases	case	NOUN
fnp-6108	237	8	with	with	ADP
fnp-6108	237	9	relative	relative	ADJ
fnp-6108	237	10	hippocampal	hippocampal	ADJ
fnp-6108	237	11	sparing	spare	VERB
fnp-6108	237	12	ad	ad	NOUN
fnp-6108	237	13	may	may	AUX
fnp-6108	237	14	account	account	VERB
fnp-6108	237	15	for	for	ADP
fnp-6108	237	16	higher	high	ADJ
fnp-6108	237	17	tau	tau	NOUN
fnp-6108	237	18	burden	burden	NOUN
fnp-6108	237	19	compared	compare	VERB
fnp-6108	237	20	to	to	ADP
fnp-6108	237	21	other	other	ADJ
fnp-6108	237	22	subtypes	subtype	NOUN
fnp-6108	237	23	.	.	PUNCT
fnp-6108	238	1	pending	pende	VERB
fnp-6108	238	2	replication	replication	NOUN
fnp-6108	238	3	,	,	PUNCT
fnp-6108	238	4	corticolimbic	corticolimbic	NOUN
fnp-6108	238	5	vulnerability	vulnerability	NOUN
fnp-6108	238	6	and	and	CCONJ
fnp-6108	238	7	tdp-43	tdp-43	NOUN
fnp-6108	238	8	co	co	NOUN
fnp-6108	238	9	-	-	NOUN
fnp-6108	238	10	pathology	pathology	NOUN
fnp-6108	238	11	should	should	AUX
fnp-6108	238	12	be	be	AUX
fnp-6108	238	13	considered	consider	VERB
fnp-6108	238	14	for	for	ADP
fnp-6108	238	15	incorporation	incorporation	NOUN
fnp-6108	238	16	into	into	ADP
fnp-6108	238	17	personalized	personalized	ADJ
fnp-6108	238	18	combination	combination	NOUN
fnp-6108	238	19	therapies	therapy	NOUN
fnp-6108	238	20	targeting	target	VERB
fnp-6108	238	21	chronic	chronic	ADJ
fnp-6108	238	22	immune	immune	ADJ
fnp-6108	238	23	dysregulation	dysregulation	NOUN
fnp-6108	238	24	.	.	PUNCT
fnp-6108	238	25	  	  	SPACE
fnp-6108	239	1	free	free	ADJ
fnp-6108	239	2	neuropathol	neuropathol	NOUN
fnp-6108	239	3	5:30:25	5:30:25	NUM
fnp-6108	239	4	neuropathological	neuropathological	ADJ
fnp-6108	239	5	subtypes	subtype	NOUN
fnp-6108	239	6	of	of	ADP
fnp-6108	239	7	lewy	lewy	ADJ
fnp-6108	239	8	body	body	NOUN
fnp-6108	239	9	disease	disease	NOUN
fnp-6108	239	10	:	:	PUNCT
fnp-6108	239	11	evidence	evidence	NOUN
fnp-6108	239	12	from	from	ADP
fnp-6108	239	13	a	a	DET
fnp-6108	239	14	population	population	NOUN
fnp-6108	239	15	-	-	PUNCT
fnp-6108	239	16	based	base	VERB
fnp-6108	239	17	study	study	NOUN
fnp-6108	239	18	liisa	liisa	PROPN
fnp-6108	239	19	myllykangas1	myllykangas1	PROPN
fnp-6108	239	20	department	department	PROPN
fnp-6108	239	21	of	of	ADP
fnp-6108	239	22	pathology	pathology	PROPN
fnp-6108	239	23	,	,	PUNCT
fnp-6108	239	24	university	university	PROPN
fnp-6108	239	25	of	of	ADP
fnp-6108	239	26	helsinki	helsinki	PROPN
fnp-6108	239	27	and	and	CCONJ
fnp-6108	239	28	hus	hus	CCONJ
fnp-6108	239	29	diagnostic	diagnostic	ADJ
fnp-6108	239	30	center	center	NOUN
fnp-6108	239	31	and	and	CCONJ
fnp-6108	239	32	helsinki	helsinki	PROPN
fnp-6108	239	33	university	university	PROPN
fnp-6108	239	34	hospital	hospital	NOUN
fnp-6108	239	35	,	,	PUNCT
fnp-6108	239	36	helsinki	helsinki	PROPN
fnp-6108	239	37	,	,	PUNCT
fnp-6108	239	38	finland	finland	PROPN
fnp-6108	239	39	evidence	evidence	NOUN
fnp-6108	239	40	from	from	ADP
fnp-6108	239	41	recent	recent	ADJ
fnp-6108	239	42	neuropathological	neuropathological	NOUN
fnp-6108	239	43	,	,	PUNCT
fnp-6108	239	44	imaging	imaging	NOUN
fnp-6108	239	45	and	and	CCONJ
fnp-6108	239	46	genetic	genetic	ADJ
fnp-6108	239	47	studies	study	NOUN
fnp-6108	239	48	has	have	AUX
fnp-6108	239	49	supported	support	VERB
fnp-6108	239	50	the	the	DET
fnp-6108	239	51	existence	existence	NOUN
fnp-6108	239	52	of	of	ADP
fnp-6108	239	53	at	at	ADV
fnp-6108	239	54	least	least	ADV
fnp-6108	239	55	two	two	NUM
fnp-6108	239	56	anatomically	anatomically	ADV
fnp-6108	239	57	distinct	distinct	ADJ
fnp-6108	239	58	lewy	lewy	PROPN
fnp-6108	239	59	-	-	PUNCT
fnp-6108	239	60	related	relate	VERB
fnp-6108	239	61	pathology	pathology	NOUN
fnp-6108	239	62	(	(	PUNCT
fnp-6108	239	63	lrp	lrp	PROPN
fnp-6108	239	64	)	)	PUNCT
fnp-6108	239	65	subtypes	subtype	NOUN
fnp-6108	239	66	consistent	consistent	ADJ
fnp-6108	239	67	with	with	ADP
fnp-6108	239	68	the	the	DET
fnp-6108	239	69	brain	brain	NOUN
fnp-6108	239	70	-	-	PUNCT
fnp-6108	239	71	first	first	ADV
fnp-6108	239	72	vs.	vs.	ADP
fnp-6108	239	73	body	body	NOUN
fnp-6108	239	74	-	-	PUNCT
fnp-6108	239	75	first	first	ADJ
fnp-6108	239	76	hypothesis	hypothesis	NOUN
fnp-6108	239	77	.	.	PUNCT
fnp-6108	240	1	one	one	NUM
fnp-6108	240	2	reason	reason	NOUN
fnp-6108	240	3	why	why	SCONJ
fnp-6108	240	4	the	the	DET
fnp-6108	240	5	anatomical	anatomical	ADJ
fnp-6108	240	6	heterogeneity	heterogeneity	NOUN
fnp-6108	240	7	of	of	ADP
fnp-6108	240	8	lrp	lrp	PROPN
fnp-6108	240	9	has	have	AUX
fnp-6108	240	10	been	be	AUX
fnp-6108	240	11	overlooked	overlook	VERB
fnp-6108	240	12	for	for	ADP
fnp-6108	240	13	a	a	DET
fnp-6108	240	14	long	long	ADJ
fnp-6108	240	15	time	time	NOUN
fnp-6108	240	16	,	,	PUNCT
fnp-6108	240	17	has	have	AUX
fnp-6108	240	18	been	be	AUX
fnp-6108	240	19	that	that	PRON
fnp-6108	240	20	research	research	NOUN
fnp-6108	240	21	has	have	AUX
fnp-6108	240	22	focused	focus	VERB
fnp-6108	240	23	on	on	ADP
fnp-6108	240	24	hypotheses	hypothesis	NOUN
fnp-6108	240	25	based	base	VERB
fnp-6108	240	26	on	on	ADP
fnp-6108	240	27	selected	select	VERB
fnp-6108	240	28	materials	material	NOUN
fnp-6108	240	29	,	,	PUNCT
fnp-6108	240	30	with	with	ADP
fnp-6108	240	31	very	very	ADV
fnp-6108	240	32	few	few	ADJ
fnp-6108	240	33	studies	study	NOUN
fnp-6108	240	34	conducted	conduct	VERB
fnp-6108	240	35	on	on	ADP
fnp-6108	240	36	unselected	unselected	ADJ
fnp-6108	240	37	population	population	NOUN
fnp-6108	240	38	-	-	PUNCT
fnp-6108	240	39	representative	representative	NOUN
fnp-6108	240	40	samples	sample	NOUN
fnp-6108	240	41	.	.	PUNCT
fnp-6108	241	1	recent	recent	ADJ
fnp-6108	241	2	studies	study	NOUN
fnp-6108	241	3	have	have	AUX
fnp-6108	241	4	also	also	ADV
fnp-6108	241	5	revealed	reveal	VERB
fnp-6108	241	6	that	that	SCONJ
fnp-6108	241	7	synucleinopathies	synucleinopathie	NOUN
fnp-6108	241	8	are	be	AUX
fnp-6108	241	9	one	one	NUM
fnp-6108	241	10	of	of	ADP
fnp-6108	241	11	the	the	DET
fnp-6108	241	12	very	very	ADV
fnp-6108	241	13	few	few	ADJ
fnp-6108	241	14	neurodegenerative	neurodegenerative	ADJ
fnp-6108	241	15	diseases	disease	NOUN
fnp-6108	241	16	that	that	PRON
fnp-6108	241	17	show	show	VERB
fnp-6108	241	18	significant	significant	ADJ
fnp-6108	241	19	involvement	involvement	NOUN
fnp-6108	241	20	of	of	ADP
fnp-6108	241	21	the	the	DET
fnp-6108	241	22	peripheral	peripheral	ADJ
fnp-6108	241	23	autonomous	autonomous	ADJ
fnp-6108	241	24	nervous	nervous	ADJ
fnp-6108	241	25	system	system	NOUN
fnp-6108	241	26	.	.	PUNCT
fnp-6108	242	1	studying	study	VERB
fnp-6108	242	2	the	the	DET
fnp-6108	242	3	spinal	spinal	ADJ
fnp-6108	242	4	cord	cord	NOUN
fnp-6108	242	5	and	and	CCONJ
fnp-6108	242	6	peripheral	peripheral	ADJ
fnp-6108	242	7	lrp	lrp	PROPN
fnp-6108	242	8	may	may	AUX
fnp-6108	242	9	therefore	therefore	ADV
fnp-6108	242	10	provide	provide	VERB
fnp-6108	242	11	a	a	DET
fnp-6108	242	12	unique	unique	ADJ
fnp-6108	242	13	window	window	NOUN
fnp-6108	242	14	into	into	ADP
fnp-6108	242	15	the	the	DET
fnp-6108	242	16	mechanisms	mechanism	NOUN
fnp-6108	242	17	for	for	ADP
fnp-6108	242	18	lewy	lewy	ADJ
fnp-6108	242	19	body	body	NOUN
fnp-6108	242	20	disorders	disorder	NOUN
fnp-6108	242	21	and	and	CCONJ
fnp-6108	242	22	the	the	DET
fnp-6108	242	23	origins	origin	NOUN
fnp-6108	242	24	of	of	ADP
fnp-6108	242	25	synuclein	synuclein	NOUN
fnp-6108	242	26	accumulation	accumulation	NOUN
fnp-6108	242	27	and	and	CCONJ
fnp-6108	242	28	spreading	spread	VERB
fnp-6108	242	29	patterns	pattern	NOUN
fnp-6108	242	30	.	.	PUNCT
fnp-6108	243	1	in	in	ADP
fnp-6108	243	2	this	this	DET
fnp-6108	243	3	presentation	presentation	NOUN
fnp-6108	243	4	,	,	PUNCT
fnp-6108	243	5	i	i	PRON
fnp-6108	243	6	review	review	VERB
fnp-6108	243	7	lrp	lrp	PROPN
fnp-6108	243	8	studies	study	NOUN
fnp-6108	243	9	in	in	ADP
fnp-6108	243	10	various	various	ADJ
fnp-6108	243	11	brain	brain	NOUN
fnp-6108	243	12	,	,	PUNCT
fnp-6108	243	13	spinal	spinal	ADJ
fnp-6108	243	14	cord	cord	NOUN
fnp-6108	243	15	and	and	CCONJ
fnp-6108	243	16	peripheral	peripheral	ADJ
fnp-6108	243	17	tissues	tissue	NOUN
fnp-6108	243	18	in	in	ADP
fnp-6108	243	19	the	the	DET
fnp-6108	243	20	unique	unique	ADJ
fnp-6108	243	21	population	population	NOUN
fnp-6108	243	22	-	-	PUNCT
fnp-6108	243	23	based	base	VERB
fnp-6108	243	24	vantaa	vantaa	ADJ
fnp-6108	243	25	85	85	NUM
fnp-6108	243	26	+	+	NUM
fnp-6108	243	27	sample	sample	NOUN
fnp-6108	243	28	set	set	NOUN
fnp-6108	243	29	(	(	PUNCT
fnp-6108	243	30	n	n	CCONJ
fnp-6108	243	31	 	 	SPACE
fnp-6108	243	32	=	=	NOUN
fnp-6108	243	33	 	 	SPACE
fnp-6108	243	34	304	304	NUM
fnp-6108	243	35	)	)	PUNCT
fnp-6108	243	36	.	.	PUNCT
fnp-6108	244	1	taken	take	VERB
fnp-6108	244	2	together	together	ADV
fnp-6108	244	3	,	,	PUNCT
fnp-6108	244	4	the	the	DET
fnp-6108	244	5	results	result	NOUN
fnp-6108	244	6	provide	provide	VERB
fnp-6108	244	7	support	support	NOUN
fnp-6108	244	8	for	for	ADP
fnp-6108	244	9	the	the	DET
fnp-6108	244	10	concept	concept	NOUN
fnp-6108	244	11	of	of	ADP
fnp-6108	244	12	at	at	ADV
fnp-6108	244	13	least	least	ADV
fnp-6108	244	14	two	two	NUM
fnp-6108	244	15	distinct	distinct	ADJ
fnp-6108	244	16	lrp	lrp	PROPN
fnp-6108	244	17	subtypes	subtype	NOUN
fnp-6108	244	18	common	common	ADJ
fnp-6108	244	19	in	in	ADP
fnp-6108	244	20	the	the	DET
fnp-6108	244	21	general	general	ADJ
fnp-6108	244	22	late	late	ADJ
fnp-6108	244	23	-	-	PUNCT
fnp-6108	244	24	life	life	NOUN
fnp-6108	244	25	population	population	NOUN
fnp-6108	244	26	.	.	PUNCT
fnp-6108	244	27	  	  	SPACE
fnp-6108	245	1	free	free	ADJ
fnp-6108	245	2	neuropathol	neuropathol	NOUN
fnp-6108	245	3	5:30:26	5:30:26	NUM
fnp-6108	245	4	disease	disease	NOUN
fnp-6108	245	5	-	-	PUNCT
fnp-6108	245	6	driving	drive	VERB
fnp-6108	245	7	mechanisms	mechanism	NOUN
fnp-6108	245	8	of	of	ADP
fnp-6108	245	9	late	late	ADJ
fnp-6108	245	10	-	-	PUNCT
fnp-6108	245	11	nc	nc	PROPN
fnp-6108	245	12	pete	pete	PROPN
fnp-6108	245	13	nelson1	nelson1	PROPN
fnp-6108	245	14	university	university	PROPN
fnp-6108	245	15	of	of	ADP
fnp-6108	245	16	kentucky	kentucky	PROPN
fnp-6108	245	17	,	,	PUNCT
fnp-6108	245	18	lexington	lexington	PROPN
fnp-6108	245	19	,	,	PUNCT
fnp-6108	245	20	ky	ky	PROPN
fnp-6108	245	21	,	,	PUNCT
fnp-6108	245	22	usa	usa	PROPN
fnp-6108	245	23	limbic	limbic	ADJ
fnp-6108	245	24	-	-	PUNCT
fnp-6108	245	25	predominant	predominant	ADJ
fnp-6108	245	26	age	age	NOUN
fnp-6108	245	27	-	-	PUNCT
fnp-6108	245	28	related	relate	VERB
fnp-6108	245	29	tdp-43	tdp-43	NOUN
fnp-6108	245	30	encephalopathy	encephalopathy	ADJ
fnp-6108	245	31	neuropathologic	neuropathologic	ADJ
fnp-6108	245	32	change	change	NOUN
fnp-6108	245	33	(	(	PUNCT
fnp-6108	245	34	late	late	PROPN
fnp-6108	245	35	-	-	PUNCT
fnp-6108	245	36	nc	nc	NOUN
fnp-6108	245	37	)	)	PUNCT
fnp-6108	245	38	is	be	AUX
fnp-6108	245	39	present	present	ADJ
fnp-6108	245	40	in	in	ADP
fnp-6108	245	41	∼30	∼30	NOUN
fnp-6108	245	42	 	 	SPACE
fnp-6108	245	43	%	%	NOUN
fnp-6108	245	44	of	of	ADP
fnp-6108	245	45	brains	brain	NOUN
fnp-6108	245	46	among	among	ADP
fnp-6108	245	47	people	people	NOUN
fnp-6108	245	48	over	over	ADP
fnp-6108	245	49	age	age	NOUN
fnp-6108	245	50	85	85	NUM
fnp-6108	245	51	at	at	ADP
fnp-6108	245	52	death	death	NOUN
fnp-6108	245	53	.	.	PUNCT
fnp-6108	246	1	consensus	consensus	NOUN
fnp-6108	246	2	-	-	PUNCT
fnp-6108	246	3	based	base	VERB
fnp-6108	246	4	classification	classification	NOUN
fnp-6108	246	5	of	of	ADP
fnp-6108	246	6	late	late	ADJ
fnp-6108	246	7	-	-	PUNCT
fnp-6108	246	8	nc	nc	PROPN
fnp-6108	246	9	has	have	AUX
fnp-6108	246	10	catalyzed	catalyze	VERB
fnp-6108	246	11	progress	progress	NOUN
fnp-6108	246	12	in	in	ADP
fnp-6108	246	13	worldwide	worldwide	ADJ
fnp-6108	246	14	efforts	effort	NOUN
fnp-6108	246	15	aimed	aim	VERB
fnp-6108	246	16	at	at	ADP
fnp-6108	246	17	conceptualizing	conceptualize	VERB
fnp-6108	246	18	,	,	PUNCT
fnp-6108	246	19	studying	study	VERB
fnp-6108	246	20	,	,	PUNCT
fnp-6108	246	21	diagnosing	diagnosing	NOUN
fnp-6108	246	22	,	,	PUNCT
fnp-6108	246	23	and	and	CCONJ
fnp-6108	246	24	ultimately	ultimately	ADV
fnp-6108	246	25	treating	treat	VERB
fnp-6108	246	26	the	the	DET
fnp-6108	246	27	condition	condition	NOUN
fnp-6108	246	28	.	.	PUNCT
fnp-6108	247	1	whereas	whereas	SCONJ
fnp-6108	247	2	late	late	PROPN
fnp-6108	247	3	-	-	PUNCT
fnp-6108	247	4	nc	nc	PROPN
fnp-6108	247	5	is	be	AUX
fnp-6108	247	6	associated	associate	VERB
fnp-6108	247	7	strongly	strongly	ADV
fnp-6108	247	8	with	with	ADP
fnp-6108	247	9	cognitive	cognitive	ADJ
fnp-6108	247	10	impairment	impairment	NOUN
fnp-6108	247	11	independent	independent	ADJ
fnp-6108	247	12	of	of	ADP
fnp-6108	247	13	other	other	ADJ
fnp-6108	247	14	pathologies	pathology	NOUN
fnp-6108	247	15	,	,	PUNCT
fnp-6108	247	16	a	a	DET
fnp-6108	247	17	subset	subset	NOUN
fnp-6108	247	18	of	of	ADP
fnp-6108	247	19	other	other	ADJ
fnp-6108	247	20	agingand	agingand	NOUN
fnp-6108	247	21	dementia	dementia	NOUN
fnp-6108	247	22	-	-	PUNCT
fnp-6108	247	23	related	relate	VERB
fnp-6108	247	24	brain	brain	NOUN
fnp-6108	247	25	pathologies	pathology	NOUN
fnp-6108	247	26	are	be	AUX
fnp-6108	247	27	seen	see	VERB
fnp-6108	247	28	with	with	ADP
fnp-6108	247	29	increased	increase	VERB
fnp-6108	247	30	frequency	frequency	NOUN
fnp-6108	247	31	in	in	ADP
fnp-6108	247	32	late	late	ADJ
fnp-6108	247	33	-	-	PUNCT
fnp-6108	247	34	nc	nc	NOUN
fnp-6108	247	35	brains	brain	NOUN
fnp-6108	247	36	.	.	PUNCT
fnp-6108	248	1	more	more	ADV
fnp-6108	248	2	specifically	specifically	ADV
fnp-6108	248	3	,	,	PUNCT
fnp-6108	248	4	hippocampal	hippocampal	ADJ
fnp-6108	248	5	sclerosis	sclerosis	NOUN
fnp-6108	248	6	(	(	PUNCT
fnp-6108	248	7	hs	hs	PROPN
fnp-6108	248	8	)	)	PUNCT
fnp-6108	248	9	,	,	PUNCT
fnp-6108	248	10	alzheimer	alzheimer	PROPN
fnp-6108	248	11	’s	’s	PART
fnp-6108	248	12	disease	disease	NOUN
fnp-6108	248	13	neuropathologic	neuropathologic	NOUN
fnp-6108	248	14	changes	change	NOUN
fnp-6108	248	15	(	(	PUNCT
fnp-6108	248	16	adnc	adnc	ADJ
fnp-6108	248	17	)	)	PUNCT
fnp-6108	248	18	,	,	PUNCT
fnp-6108	248	19	age	age	NOUN
fnp-6108	248	20	-	-	PUNCT
fnp-6108	248	21	related	relate	VERB
fnp-6108	248	22	tau	tau	PROPN
fnp-6108	248	23	astrogliopathy	astrogliopathy	ADJ
fnp-6108	248	24	(	(	PUNCT
fnp-6108	248	25	artag	artag	ADJ
fnp-6108	248	26	)	)	PUNCT
fnp-6108	248	27	,	,	PUNCT
fnp-6108	248	28	and	and	CCONJ
fnp-6108	248	29	brain	brain	NOUN
fnp-6108	248	30	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	248	31	are	be	AUX
fnp-6108	248	32	each	each	PRON
fnp-6108	248	33	relatively	relatively	ADV
fnp-6108	248	34	common	common	ADJ
fnp-6108	248	35	in	in	ADP
fnp-6108	248	36	brains	brain	NOUN
fnp-6108	248	37	with	with	ADP
fnp-6108	248	38	comorbid	comorbid	NOUN
fnp-6108	248	39	late	late	PROPN
fnp-6108	248	40	-	-	PUNCT
fnp-6108	248	41	nc	nc	PROPN
fnp-6108	248	42	(	(	PUNCT
fnp-6108	248	43	and	and	CCONJ
fnp-6108	248	44	vice	vice	ADV
fnp-6108	248	45	versa	versa	ADV
fnp-6108	248	46	!	!	PUNCT
fnp-6108	249	1	in	in	ADP
fnp-6108	249	2	community	community	NOUN
fnp-6108	249	3	-	-	PUNCT
fnp-6108	249	4	based	base	VERB
fnp-6108	249	5	autopsy	autopsy	ADJ
fnp-6108	249	6	cohorts	cohort	NOUN
fnp-6108	249	7	,	,	PUNCT
fnp-6108	249	8	“	"	PUNCT
fnp-6108	249	9	pure	pure	ADJ
fnp-6108	249	10	late	late	ADJ
fnp-6108	249	11	-	-	PUNCT
fnp-6108	249	12	nc	nc	PROPN
fnp-6108	249	13	”	"	PUNCT
fnp-6108	249	14	is	be	AUX
fnp-6108	249	15	unusual	unusual	ADJ
fnp-6108	249	16	,	,	PUNCT
fnp-6108	249	17	and	and	CCONJ
fnp-6108	249	18	“	"	PUNCT
fnp-6108	249	19	pure	pure	ADJ
fnp-6108	249	20	adnc	adnc	NOUN
fnp-6108	249	21	”	"	PUNCT
fnp-6108	249	22	also	also	ADV
fnp-6108	249	23	is	be	AUX
fnp-6108	249	24	unusual	unusual	ADJ
fnp-6108	249	25	,	,	PUNCT
fnp-6108	249	26	because	because	SCONJ
fnp-6108	249	27	mixed	mixed	ADJ
fnp-6108	249	28	pathologies	pathology	NOUN
fnp-6108	249	29	are	be	AUX
fnp-6108	249	30	the	the	DET
fnp-6108	249	31	norm	norm	NOUN
fnp-6108	249	32	.	.	PUNCT
fnp-6108	249	33	)	)	PUNCT
fnp-6108	249	34	.	.	PUNCT
fnp-6108	250	1	analyses	analysis	NOUN
fnp-6108	250	2	of	of	ADP
fnp-6108	250	3	high	high	ADJ
fnp-6108	250	4	-	-	PUNCT
fnp-6108	250	5	quality	quality	NOUN
fnp-6108	250	6	autopsy	autopsy	ADJ
fnp-6108	250	7	cohorts	cohort	NOUN
fnp-6108	250	8	’	'	PUNCT
fnp-6108	250	9	data	datum	NOUN
fnp-6108	250	10	provide	provide	VERB
fnp-6108	250	11	critical	critical	ADJ
fnp-6108	250	12	insights	insight	NOUN
fnp-6108	250	13	into	into	ADP
fnp-6108	250	14	underlying	underlie	VERB
fnp-6108	250	15	disease	disease	NOUN
fnp-6108	250	16	-	-	PUNCT
fnp-6108	250	17	associated	associate	VERB
fnp-6108	250	18	biologic	biologic	NOUN
fnp-6108	250	19	phenomena	phenomenon	NOUN
fnp-6108	250	20	,	,	PUNCT
fnp-6108	250	21	including	include	VERB
fnp-6108	250	22	evidence	evidence	NOUN
fnp-6108	250	23	of	of	ADP
fnp-6108	250	24	mechanistic	mechanistic	ADJ
fnp-6108	250	25	interactions	interaction	NOUN
fnp-6108	250	26	(	(	PUNCT
fnp-6108	250	27	“	"	PUNCT
fnp-6108	250	28	synergies	synergy	NOUN
fnp-6108	250	29	”	"	PUNCT
fnp-6108	250	30	)	)	PUNCT
fnp-6108	250	31	between	between	ADP
fnp-6108	250	32	the	the	DET
fnp-6108	250	33	different	different	ADJ
fnp-6108	250	34	pathologic	pathologic	ADJ
fnp-6108	250	35	subtypes	subtype	NOUN
fnp-6108	250	36	,	,	PUNCT
fnp-6108	250	37	while	while	SCONJ
fnp-6108	250	38	also	also	ADV
fnp-6108	250	39	suggesting	suggest	VERB
fnp-6108	250	40	common	common	ADJ
fnp-6108	250	41	upstream	upstream	ADJ
fnp-6108	250	42	influences	influence	NOUN
fnp-6108	250	43	.	.	PUNCT
fnp-6108	251	1	genes	gene	NOUN
fnp-6108	251	2	with	with	ADP
fnp-6108	251	3	variants	variant	NOUN
fnp-6108	251	4	associated	associate	VERB
fnp-6108	251	5	with	with	ADP
fnp-6108	251	6	late	late	ADJ
fnp-6108	251	7	-	-	PUNCT
fnp-6108	251	8	nc	nc	PROPN
fnp-6108	251	9	risk	risk	NOUN
fnp-6108	251	10	include	include	VERB
fnp-6108	251	11	tmem106by	tmem106by	NUM
fnp-6108	251	12	,	,	PUNCT
fnp-6108	251	13	grn	grn	PROPN
fnp-6108	251	14	,	,	PUNCT
fnp-6108	251	15	apoe	apoe	NOUN
fnp-6108	251	16	,	,	PUNCT
fnp-6108	251	17	sorl1	sorl1	PROPN
fnp-6108	251	18	,	,	PUNCT
fnp-6108	251	19	abcc9	abcc9	NOUN
fnp-6108	251	20	,	,	PUNCT
fnp-6108	251	21	and	and	CCONJ
fnp-6108	251	22	tpcn1	tpcn1	NOUN
fnp-6108	251	23	.	.	PUNCT
fnp-6108	252	1	among	among	ADP
fnp-6108	252	2	these	these	PRON
fnp-6108	252	3	,	,	PUNCT
fnp-6108	252	4	different	different	ADJ
fnp-6108	252	5	genetic	genetic	ADJ
fnp-6108	252	6	variants	variant	NOUN
fnp-6108	252	7	are	be	AUX
fnp-6108	252	8	specifically	specifically	ADV
fnp-6108	252	9	associated	associate	VERB
fnp-6108	252	10	with	with	ADP
fnp-6108	252	11	(	(	PUNCT
fnp-6108	252	12	i.e.	i.e.	X
fnp-6108	252	13	,	,	PUNCT
fnp-6108	252	14	appear	appear	VERB
fnp-6108	252	15	to	to	PART
fnp-6108	252	16	influence	influence	VERB
fnp-6108	252	17	biologically	biologically	ADV
fnp-6108	252	18	)	)	PUNCT
fnp-6108	253	1	distinct	distinct	ADJ
fnp-6108	253	2	components	component	NOUN
fnp-6108	253	3	of	of	ADP
fnp-6108	253	4	pathogenetic	pathogenetic	ADJ
fnp-6108	253	5	pathways	pathway	NOUN
fnp-6108	253	6	,	,	PUNCT
fnp-6108	253	7	and	and	CCONJ
fnp-6108	253	8	may	may	AUX
fnp-6108	253	9	help	help	VERB
fnp-6108	253	10	to	to	PART
fnp-6108	253	11	explain	explain	VERB
fnp-6108	253	12	why	why	SCONJ
fnp-6108	253	13	some	some	PRON
fnp-6108	253	14	but	but	CCONJ
fnp-6108	253	15	not	not	PART
fnp-6108	253	16	all	all	PRON
fnp-6108	253	17	late	late	ADJ
fnp-6108	253	18	-	-	PUNCT
fnp-6108	253	19	nc+	nc+	NOUN
fnp-6108	253	20	brains	brain	NOUN
fnp-6108	253	21	have	have	VERB
fnp-6108	253	22	comorbid	comorbid	NOUN
fnp-6108	253	23	hs	hs	PRON
fnp-6108	253	24	,	,	PUNCT
fnp-6108	253	25	and	and	CCONJ
fnp-6108	253	26	why	why	SCONJ
fnp-6108	253	27	some	some	PRON
fnp-6108	253	28	but	but	CCONJ
fnp-6108	253	29	not	not	PART
fnp-6108	253	30	all	all	PRON
fnp-6108	253	31	late	late	ADJ
fnp-6108	253	32	-	-	PUNCT
fnp-6108	253	33	nc+	nc+	NOUN
fnp-6108	253	34	brains	brain	NOUN
fnp-6108	253	35	have	have	VERB
fnp-6108	253	36	comorbid	comorbid	NOUN
fnp-6108	253	37	adnc	adnc	ADV
fnp-6108	253	38	.	.	PUNCT
fnp-6108	254	1	the	the	DET
fnp-6108	254	2	association	association	NOUN
fnp-6108	254	3	between	between	ADP
fnp-6108	254	4	late	late	PROPN
fnp-6108	254	5	-	-	PUNCT
fnp-6108	254	6	nc	nc	PROPN
fnp-6108	254	7	and	and	CCONJ
fnp-6108	254	8	brain	brain	NOUN
fnp-6108	254	9	arteriolosclerosis	arteriolosclerosis	NOUN
fnp-6108	254	10	also	also	ADV
fnp-6108	254	11	has	have	VERB
fnp-6108	254	12	intriguing	intriguing	ADJ
fnp-6108	254	13	implications	implication	NOUN
fnp-6108	254	14	.	.	PUNCT
fnp-6108	255	1	overall	overall	ADJ
fnp-6108	255	2	,	,	PUNCT
fnp-6108	255	3	salient	salient	ADJ
fnp-6108	255	4	late	late	ADJ
fnp-6108	255	5	-	-	PUNCT
fnp-6108	255	6	nc	nc	NOUN
fnp-6108	255	7	-	-	PUNCT
fnp-6108	255	8	associated	associate	VERB
fnp-6108	255	9	pathobiologic	pathobiologic	ADJ
fnp-6108	255	10	factors	factor	NOUN
fnp-6108	255	11	in	in	ADP
fnp-6108	255	12	aged	aged	ADJ
fnp-6108	255	13	brains	brain	NOUN
fnp-6108	255	14	include	include	VERB
fnp-6108	255	15	tau	tau	PROPN
fnp-6108	255	16	proteinopathy	proteinopathy	ADJ
fnp-6108	255	17	,	,	PUNCT
fnp-6108	255	18	endolysosomal	endolysosomal	ADJ
fnp-6108	255	19	pathways	pathway	NOUN
fnp-6108	255	20	,	,	PUNCT
fnp-6108	255	21	and	and	CCONJ
fnp-6108	255	22	blood	blood	NOUN
fnp-6108	255	23	-	-	PUNCT
fnp-6108	255	24	brain	brain	NOUN
fnp-6108	255	25	barrier	barrier	NOUN
fnp-6108	255	26	dysfunction	dysfunction	NOUN
fnp-6108	255	27	.	.	PUNCT
fnp-6108	256	1	we	we	PRON
fnp-6108	256	2	conclude	conclude	VERB
fnp-6108	256	3	that	that	SCONJ
fnp-6108	256	4	the	the	DET
fnp-6108	256	5	study	study	NOUN
fnp-6108	256	6	of	of	ADP
fnp-6108	256	7	neuropathologic	neuropathologic	ADJ
fnp-6108	256	8	phenomenology	phenomenology	NOUN
fnp-6108	256	9	provides	provide	VERB
fnp-6108	256	10	clues	clue	NOUN
fnp-6108	256	11	about	about	ADP
fnp-6108	256	12	disease	disease	NOUN
fnp-6108	256	13	-	-	PUNCT
fnp-6108	256	14	driving	drive	VERB
fnp-6108	256	15	mechanisms	mechanism	NOUN
fnp-6108	256	16	,	,	PUNCT
fnp-6108	256	17	and	and	CCONJ
fnp-6108	256	18	may	may	AUX
fnp-6108	256	19	also	also	ADV
fnp-6108	256	20	yield	yield	VERB
fnp-6108	256	21	insights	insight	NOUN
fnp-6108	256	22	into	into	ADP
fnp-6108	256	23	diagnostic	diagnostic	ADJ
fnp-6108	256	24	and	and	CCONJ
fnp-6108	256	25	therapeutic	therapeutic	ADJ
fnp-6108	256	26	targets	target	NOUN
fnp-6108	256	27	.	.	PUNCT
fnp-6108	256	28	  	  	SPACE
fnp-6108	257	1	free	free	ADJ
fnp-6108	257	2	neuropathol	neuropathol	NOUN
fnp-6108	257	3	5:30:27	5:30:27	NUM
fnp-6108	257	4	evaluating	evaluate	VERB
fnp-6108	257	5	the	the	DET
fnp-6108	257	6	impact	impact	NOUN
fnp-6108	257	7	of	of	ADP
fnp-6108	257	8	data	datum	NOUN
fnp-6108	257	9	harmonization	harmonization	NOUN
fnp-6108	257	10	on	on	ADP
fnp-6108	257	11	multi	multi	ADJ
fnp-6108	257	12	-	-	ADJ
fnp-6108	257	13	site	site	ADJ
fnp-6108	257	14	simulated	simulate	VERB
fnp-6108	257	15	neurodegeneration	neurodegeneration	NOUN
fnp-6108	257	16	dataset	dataset	NOUN
fnp-6108	257	17	analysis	analysis	NOUN
fnp-6108	257	18	mithilesh	mithilesh	NOUN
fnp-6108	257	19	prakash1	prakash1	NOUN
fnp-6108	257	20	,	,	PUNCT
fnp-6108	257	21	jussi	jussi	PROPN
fnp-6108	257	22	tohka1	tohka1	PROPN
fnp-6108	257	23	a.i	a.i	PROPN
fnp-6108	257	24	.	.	PROPN
fnp-6108	257	25	virtanen	virtanen	PROPN
fnp-6108	257	26	institute	institute	PROPN
fnp-6108	257	27	for	for	ADP
fnp-6108	257	28	molecular	molecular	ADJ
fnp-6108	257	29	sciences	science	NOUN
fnp-6108	257	30	,	,	PUNCT
fnp-6108	257	31	university	university	NOUN
fnp-6108	257	32	of	of	ADP
fnp-6108	257	33	eastern	eastern	PROPN
fnp-6108	257	34	finland	finland	PROPN
fnp-6108	257	35	,	,	PUNCT
fnp-6108	257	36	kuopio	kuopio	PROPN
fnp-6108	257	37	,	,	PUNCT
fnp-6108	257	38	finland	finland	PROPN
fnp-6108	257	39	a	a	DET
fnp-6108	257	40	study	study	NOUN
fnp-6108	257	41	was	be	AUX
fnp-6108	257	42	conducted	conduct	VERB
fnp-6108	257	43	to	to	PART
fnp-6108	257	44	evaluate	evaluate	VERB
fnp-6108	257	45	the	the	DET
fnp-6108	257	46	impact	impact	NOUN
fnp-6108	257	47	of	of	ADP
fnp-6108	257	48	raw	raw	ADJ
fnp-6108	257	49	and	and	CCONJ
fnp-6108	257	50	harmonized	harmonized	ADJ
fnp-6108	257	51	data	datum	NOUN
fnp-6108	257	52	on	on	ADP
fnp-6108	257	53	downstream	downstream	ADJ
fnp-6108	257	54	analysis	analysis	NOUN
fnp-6108	257	55	,	,	PUNCT
fnp-6108	257	56	employing	employ	VERB
fnp-6108	257	57	a	a	DET
fnp-6108	257	58	simulated	simulated	ADJ
fnp-6108	257	59	multi	multi	ADJ
fnp-6108	257	60	-	-	ADJ
fnp-6108	257	61	site	site	ADJ
fnp-6108	257	62	neurodegeneration	neurodegeneration	NOUN
fnp-6108	257	63	dataset	dataset	NOUN
fnp-6108	257	64	.	.	PUNCT
fnp-6108	258	1	the	the	DET
fnp-6108	258	2	synthetic	synthetic	ADJ
fnp-6108	258	3	dataset	dataset	NOUN
fnp-6108	258	4	,	,	PUNCT
fnp-6108	258	5	created	create	VERB
fnp-6108	258	6	using	use	VERB
fnp-6108	258	7	a	a	DET
fnp-6108	258	8	python	python	NOUN
fnp-6108	258	9	function	function	NOUN
fnp-6108	258	10	,	,	PUNCT
fnp-6108	258	11	included	include	VERB
fnp-6108	258	12	mri	mri	NOUN
fnp-6108	258	13	volumes	volume	NOUN
fnp-6108	258	14	,	,	PUNCT
fnp-6108	258	15	demographics	demographic	NOUN
fnp-6108	258	16	,	,	PUNCT
fnp-6108	258	17	and	and	CCONJ
fnp-6108	258	18	groupings	grouping	NOUN
fnp-6108	258	19	for	for	ADP
fnp-6108	258	20	5000	5000	NUM
fnp-6108	258	21	subjects	subject	NOUN
fnp-6108	258	22	across	across	ADP
fnp-6108	258	23	four	four	NUM
fnp-6108	258	24	simulated	simulated	ADJ
fnp-6108	258	25	sites	site	NOUN
fnp-6108	258	26	.	.	PUNCT
fnp-6108	259	1	the	the	DET
fnp-6108	259	2	data	datum	NOUN
fnp-6108	259	3	were	be	AUX
fnp-6108	259	4	modeled	model	VERB
fnp-6108	259	5	,	,	PUNCT
fnp-6108	259	6	with	with	ADP
fnp-6108	259	7	an	an	DET
fnp-6108	259	8	xgboost	xgboost	ADV
fnp-6108	259	9	classifier	classifier	NOUN
fnp-6108	259	10	,	,	PUNCT
fnp-6108	259	11	as	as	ADP
fnp-6108	259	12	either	either	CCONJ
fnp-6108	259	13	pooled	pooled	ADJ
fnp-6108	259	14	(	(	PUNCT
fnp-6108	259	15	raw	raw	ADJ
fnp-6108	259	16	)	)	PUNCT
fnp-6108	259	17	or	or	CCONJ
fnp-6108	259	18	harmonized	harmonized	ADJ
fnp-6108	259	19	using	use	VERB
fnp-6108	259	20	a	a	DET
fnp-6108	259	21	combat	combat	NOUN
fnp-6108	259	22	variant	variant	NOUN
fnp-6108	259	23	called	call	VERB
fnp-6108	259	24	neuroharmonize	neuroharmonize	NOUN
fnp-6108	259	25	.	.	PUNCT
fnp-6108	260	1	the	the	DET
fnp-6108	260	2	models	model	NOUN
fnp-6108	260	3	were	be	AUX
fnp-6108	260	4	evaluated	evaluate	VERB
fnp-6108	260	5	using	use	VERB
fnp-6108	260	6	a	a	DET
fnp-6108	260	7	“	"	PUNCT
fnp-6108	260	8	leave	leave	VERB
fnp-6108	260	9	one	one	NUM
fnp-6108	260	10	site	site	NOUN
fnp-6108	260	11	out	out	ADP
fnp-6108	260	12	”	"	PUNCT
fnp-6108	260	13	approach	approach	NOUN
fnp-6108	260	14	.	.	PUNCT
fnp-6108	261	1	two	two	NUM
fnp-6108	261	2	scenarios	scenario	NOUN
fnp-6108	261	3	were	be	AUX
fnp-6108	261	4	examined	examine	VERB
fnp-6108	261	5	.	.	PUNCT
fnp-6108	262	1	in	in	ADP
fnp-6108	262	2	scenario	scenario	NOUN
fnp-6108	262	3	1	1	NUM
fnp-6108	262	4	,	,	PUNCT
fnp-6108	262	5	certain	certain	ADJ
fnp-6108	262	6	volumes	volume	NOUN
fnp-6108	262	7	were	be	AUX
fnp-6108	262	8	atrophied	atrophy	VERB
fnp-6108	262	9	where	where	SCONJ
fnp-6108	262	10	the	the	DET
fnp-6108	262	11	label	label	NOUN
fnp-6108	262	12	was	be	AUX
fnp-6108	262	13	1	1	NUM
fnp-6108	262	14	.	.	PUNCT
fnp-6108	263	1	both	both	CCONJ
fnp-6108	263	2	raw	raw	ADJ
fnp-6108	263	3	and	and	CCONJ
fnp-6108	263	4	harmonized	harmonized	ADJ
fnp-6108	263	5	data	datum	NOUN
fnp-6108	263	6	overfit	overfit	VERB
fnp-6108	263	7	the	the	DET
fnp-6108	263	8	training	training	NOUN
fnp-6108	263	9	data	datum	NOUN
fnp-6108	263	10	(	(	PUNCT
fnp-6108	263	11	auc	auc	NOUN
fnp-6108	263	12	 	 	SPACE
fnp-6108	263	13	=	=	NOUN
fnp-6108	263	14	 	 	SPACE
fnp-6108	263	15	1.0	1.0	NUM
fnp-6108	263	16	)	)	PUNCT
fnp-6108	263	17	,	,	PUNCT
fnp-6108	263	18	but	but	CCONJ
fnp-6108	263	19	harmonization	harmonization	NOUN
fnp-6108	263	20	more	more	ADV
fnp-6108	263	21	accurately	accurately	ADV
fnp-6108	263	22	reflected	reflect	VERB
fnp-6108	263	23	the	the	DET
fnp-6108	263	24	classifier	classifier	NOUN
fnp-6108	263	25	’s	’s	PART
fnp-6108	263	26	performance	performance	NOUN
fnp-6108	263	27	in	in	ADP
fnp-6108	263	28	the	the	DET
fnp-6108	263	29	test	test	NOUN
fnp-6108	263	30	folds	fold	NOUN
fnp-6108	263	31	(	(	PUNCT
fnp-6108	263	32	auc	auc	NOUN
fnp-6108	263	33	:	:	PUNCT
fnp-6108	263	34	0.5	0.5	NUM
fnp-6108	263	35	vs.	vs.	ADP
fnp-6108	263	36	1.0	1.0	NUM
fnp-6108	263	37	for	for	ADP
fnp-6108	263	38	raw	raw	ADJ
fnp-6108	263	39	)	)	PUNCT
fnp-6108	263	40	.	.	PUNCT
fnp-6108	264	1	in	in	ADP
fnp-6108	264	2	scenario	scenario	NOUN
fnp-6108	264	3	2	2	NUM
fnp-6108	264	4	,	,	PUNCT
fnp-6108	264	5	with	with	ADP
fnp-6108	264	6	no	no	DET
fnp-6108	264	7	atrophy	atrophy	NOUN
fnp-6108	264	8	,	,	PUNCT
fnp-6108	264	9	both	both	DET
fnp-6108	264	10	data	datum	NOUN
fnp-6108	264	11	types	type	NOUN
fnp-6108	264	12	overfit	overfit	VERB
fnp-6108	264	13	the	the	DET
fnp-6108	264	14	training	training	NOUN
fnp-6108	264	15	data	datum	NOUN
fnp-6108	264	16	(	(	PUNCT
fnp-6108	264	17	auc	auc	NOUN
fnp-6108	264	18	:	:	PUNCT
fnp-6108	264	19	∼0.9	∼0.9	PROPN
fnp-6108	264	20	)	)	PUNCT
fnp-6108	264	21	,	,	PUNCT
fnp-6108	264	22	but	but	CCONJ
fnp-6108	264	23	the	the	DET
fnp-6108	264	24	test	test	NOUN
fnp-6108	264	25	data	datum	NOUN
fnp-6108	264	26	showed	show	VERB
fnp-6108	264	27	anticipated	anticipate	VERB
fnp-6108	264	28	results	result	NOUN
fnp-6108	264	29	(	(	PUNCT
fnp-6108	264	30	auc	auc	NOUN
fnp-6108	264	31	:	:	PUNCT
fnp-6108	264	32	∼0.5	∼0.5	NOUN
fnp-6108	264	33	)	)	PUNCT
fnp-6108	264	34	,	,	PUNCT
fnp-6108	264	35	with	with	ADP
fnp-6108	264	36	harmonized	harmonized	ADJ
fnp-6108	264	37	data	datum	NOUN
fnp-6108	264	38	showing	show	VERB
fnp-6108	264	39	less	less	ADJ
fnp-6108	264	40	variation	variation	NOUN
fnp-6108	264	41	.	.	PUNCT
fnp-6108	265	1	the	the	DET
fnp-6108	265	2	study	study	NOUN
fnp-6108	265	3	concluded	conclude	VERB
fnp-6108	265	4	that	that	SCONJ
fnp-6108	265	5	the	the	DET
fnp-6108	265	6	effectiveness	effectiveness	NOUN
fnp-6108	265	7	of	of	ADP
fnp-6108	265	8	harmonization	harmonization	NOUN
fnp-6108	265	9	compared	compare	VERB
fnp-6108	265	10	to	to	ADP
fnp-6108	265	11	pooling	pool	VERB
fnp-6108	265	12	of	of	ADP
fnp-6108	265	13	data	datum	NOUN
fnp-6108	265	14	is	be	AUX
fnp-6108	265	15	determined	determine	VERB
fnp-6108	265	16	by	by	ADP
fnp-6108	265	17	the	the	DET
fnp-6108	265	18	dataset	dataset	NOUN
fnp-6108	265	19	.	.	PUNCT
fnp-6108	266	1	harmonization	harmonization	NOUN
fnp-6108	266	2	is	be	AUX
fnp-6108	266	3	preferable	preferable	ADJ
fnp-6108	266	4	in	in	ADP
fnp-6108	266	5	multi	multi	ADJ
fnp-6108	266	6	-	-	ADJ
fnp-6108	266	7	site	site	ADJ
fnp-6108	266	8	data	datum	NOUN
fnp-6108	266	9	as	as	SCONJ
fnp-6108	266	10	it	it	PRON
fnp-6108	266	11	provides	provide	VERB
fnp-6108	266	12	results	result	NOUN
fnp-6108	266	13	closer	close	ADV
fnp-6108	266	14	to	to	ADP
fnp-6108	266	15	those	those	PRON
fnp-6108	266	16	anticipated	anticipate	VERB
fnp-6108	266	17	in	in	ADP
fnp-6108	266	18	controlled	control	VERB
fnp-6108	266	19	settings	setting	NOUN
fnp-6108	266	20	.	.	PUNCT
fnp-6108	267	1	however	however	ADV
fnp-6108	267	2	,	,	PUNCT
fnp-6108	267	3	in	in	ADP
fnp-6108	267	4	certain	certain	ADJ
fnp-6108	267	5	circumstances	circumstance	NOUN
fnp-6108	267	6	,	,	PUNCT
fnp-6108	267	7	such	such	ADJ
fnp-6108	267	8	as	as	ADP
fnp-6108	267	9	when	when	SCONJ
fnp-6108	267	10	the	the	DET
fnp-6108	267	11	predictors	predictor	NOUN
fnp-6108	267	12	and	and	CCONJ
fnp-6108	267	13	labels	label	NOUN
fnp-6108	267	14	are	be	AUX
fnp-6108	267	15	highly	highly	ADV
fnp-6108	267	16	correlated	correlate	VERB
fnp-6108	267	17	,	,	PUNCT
fnp-6108	267	18	raw	raw	ADJ
fnp-6108	267	19	data	datum	NOUN
fnp-6108	267	20	can	can	AUX
fnp-6108	267	21	outperform	outperform	VERB
fnp-6108	267	22	harmonized	harmonized	ADJ
fnp-6108	267	23	datasets	dataset	NOUN
fnp-6108	267	24	.	.	PUNCT
fnp-6108	268	1	further	further	ADJ
fnp-6108	268	2	research	research	NOUN
fnp-6108	268	3	is	be	AUX
fnp-6108	268	4	needed	need	VERB
fnp-6108	268	5	to	to	PART
fnp-6108	268	6	optimize	optimize	VERB
fnp-6108	268	7	the	the	DET
fnp-6108	268	8	use	use	NOUN
fnp-6108	268	9	of	of	ADP
fnp-6108	268	10	harmonization	harmonization	NOUN
fnp-6108	268	11	in	in	ADP
fnp-6108	268	12	multi	multi	ADJ
fnp-6108	268	13	-	-	ADJ
fnp-6108	268	14	site	site	ADJ
fnp-6108	268	15	neurodegeneration	neurodegeneration	NOUN
fnp-6108	268	16	studies	study	NOUN
fnp-6108	268	17	,	,	PUNCT
fnp-6108	268	18	particularly	particularly	ADV
fnp-6108	268	19	in	in	ADP
fnp-6108	268	20	the	the	DET
fnp-6108	268	21	context	context	NOUN
fnp-6108	268	22	of	of	ADP
fnp-6108	268	23	simulated	simulated	ADJ
fnp-6108	268	24	atrophy	atrophy	NOUN
fnp-6108	268	25	.	.	PUNCT
fnp-6108	268	26	  	  	SPACE
fnp-6108	269	1	free	free	ADJ
fnp-6108	269	2	neuropathol	neuropathol	NOUN
fnp-6108	269	3	5:30:28	5:30:28	PROPN
fnp-6108	269	4	tdp-43	tdp-43	PROPN
fnp-6108	269	5	pathology	pathology	NOUN
fnp-6108	269	6	in	in	ADP
fnp-6108	269	7	frontal	frontal	ADJ
fnp-6108	269	8	cortical	cortical	ADJ
fnp-6108	269	9	brain	brain	NOUN
fnp-6108	269	10	biopsies	biopsy	NOUN
fnp-6108	269	11	of	of	ADP
fnp-6108	269	12	normal	normal	ADJ
fnp-6108	269	13	pressure	pressure	NOUN
fnp-6108	269	14	hydrocephalus	hydrocephalus	NOUN
fnp-6108	269	15	patients	patient	NOUN
fnp-6108	269	16	eino	eino	PROPN
fnp-6108	269	17	solje1,2	solje1,2	PROPN
fnp-6108	269	18	,	,	PUNCT
fnp-6108	269	19	ville	ville	PROPN
fnp-6108	269	20	korhonen3,4	korhonen3,4	PROPN
fnp-6108	269	21	,	,	PUNCT
fnp-6108	269	22	anssi	anssi	PROPN
fnp-6108	269	23	lipponen5	lipponen5	PROPN
fnp-6108	269	24	,	,	PUNCT
fnp-6108	269	25	annakaisa	annakaisa	PROPN
fnp-6108	269	26	haapasalo6	haapasalo6	PROPN
fnp-6108	269	27	,	,	PUNCT
fnp-6108	269	28	mikko	mikko	PROPN
fnp-6108	269	29	hiltunen5	hiltunen5	PROPN
fnp-6108	269	30	,	,	PUNCT
fnp-6108	269	31	ville	ville	PROPN
fnp-6108	269	32	leinonen3,4	leinonen3,4	PROPN
fnp-6108	269	33	,	,	PUNCT
fnp-6108	269	34	tuomas	tuomas	PROPN
fnp-6108	269	35	rauramaa7,8	rauramaa7,8	PROPN
fnp-6108	269	36	institute	institute	PROPN
fnp-6108	269	37	of	of	ADP
fnp-6108	269	38	clinical	clinical	ADJ
fnp-6108	269	39	medicine	medicine	NOUN
fnp-6108	269	40	neurology	neurology	NOUN
fnp-6108	269	41	,	,	PUNCT
fnp-6108	269	42	university	university	NOUN
fnp-6108	269	43	of	of	ADP
fnp-6108	269	44	eastern	eastern	PROPN
fnp-6108	269	45	finland	finland	PROPN
fnp-6108	269	46	,	,	PUNCT
fnp-6108	269	47	kuopio	kuopio	PROPN
fnp-6108	269	48	,	,	PUNCT
fnp-6108	269	49	finland	finland	PROPN
fnp-6108	269	50	neuro	neuro	PROPN
fnp-6108	269	51	center	center	PROPN
fnp-6108	269	52	,	,	PUNCT
fnp-6108	269	53	neurology	neurology	NOUN
fnp-6108	269	54	,	,	PUNCT
fnp-6108	269	55	kuopio	kuopio	NOUN
fnp-6108	269	56	university	university	NOUN
fnp-6108	269	57	hospital	hospital	NOUN
fnp-6108	269	58	,	,	PUNCT
fnp-6108	269	59	kuopio	kuopio	PROPN
fnp-6108	269	60	,	,	PUNCT
fnp-6108	269	61	finland	finland	PROPN
fnp-6108	269	62	institute	institute	PROPN
fnp-6108	269	63	of	of	ADP
fnp-6108	269	64	clinical	clinical	ADJ
fnp-6108	269	65	medicine	medicine	NOUN
fnp-6108	269	66	neurosurgery	neurosurgery	NOUN
fnp-6108	269	67	,	,	PUNCT
fnp-6108	269	68	university	university	NOUN
fnp-6108	269	69	of	of	ADP
fnp-6108	269	70	eastern	eastern	PROPN
fnp-6108	269	71	finland	finland	PROPN
fnp-6108	269	72	,	,	PUNCT
fnp-6108	269	73	kuopio	kuopio	PROPN
fnp-6108	269	74	,	,	PUNCT
fnp-6108	269	75	finland	finland	PROPN
fnp-6108	269	76	department	department	PROPN
fnp-6108	269	77	of	of	ADP
fnp-6108	269	78	neurosurgery	neurosurgery	NOUN
fnp-6108	269	79	,	,	PUNCT
fnp-6108	269	80	kuopio	kuopio	PROPN
fnp-6108	269	81	university	university	NOUN
fnp-6108	269	82	hospital	hospital	NOUN
fnp-6108	269	83	,	,	PUNCT
fnp-6108	269	84	kuopio	kuopio	PROPN
fnp-6108	269	85	,	,	PUNCT
fnp-6108	269	86	finland	finland	PROPN
fnp-6108	269	87	institute	institute	PROPN
fnp-6108	269	88	of	of	ADP
fnp-6108	269	89	biomedicine	biomedicine	NOUN
fnp-6108	269	90	,	,	PUNCT
fnp-6108	269	91	faculty	faculty	NOUN
fnp-6108	269	92	of	of	ADP
fnp-6108	269	93	health	health	NOUN
fnp-6108	269	94	sciences	sciences	PROPN
fnp-6108	269	95	,	,	PUNCT
fnp-6108	269	96	university	university	NOUN
fnp-6108	269	97	of	of	ADP
fnp-6108	269	98	eastern	eastern	PROPN
fnp-6108	269	99	finland	finland	PROPN
fnp-6108	269	100	,	,	PUNCT
fnp-6108	269	101	kuopio	kuopio	PROPN
fnp-6108	269	102	,	,	PUNCT
fnp-6108	269	103	finland	finland	PROPN
fnp-6108	269	104	a.i	a.i	PROPN
fnp-6108	269	105	.	.	PROPN
fnp-6108	269	106	virtanen	virtanen	PROPN
fnp-6108	269	107	institute	institute	PROPN
fnp-6108	269	108	for	for	ADP
fnp-6108	269	109	molecular	molecular	ADJ
fnp-6108	269	110	sciences	science	NOUN
fnp-6108	269	111	,	,	PUNCT
fnp-6108	269	112	university	university	NOUN
fnp-6108	269	113	of	of	ADP
fnp-6108	269	114	eastern	eastern	PROPN
fnp-6108	269	115	finland	finland	PROPN
fnp-6108	269	116	,	,	PUNCT
fnp-6108	269	117	kuopio	kuopio	PROPN
fnp-6108	269	118	,	,	PUNCT
fnp-6108	269	119	finland	finland	PROPN
fnp-6108	269	120	institute	institute	PROPN
fnp-6108	269	121	of	of	ADP
fnp-6108	269	122	clinical	clinical	ADJ
fnp-6108	269	123	medicine	medicine	NOUN
fnp-6108	269	124	pathology	pathology	NOUN
fnp-6108	269	125	,	,	PUNCT
fnp-6108	269	126	university	university	PROPN
fnp-6108	269	127	of	of	ADP
fnp-6108	269	128	eastern	eastern	PROPN
fnp-6108	269	129	finland	finland	PROPN
fnp-6108	269	130	,	,	PUNCT
fnp-6108	269	131	kuopio	kuopio	PROPN
fnp-6108	269	132	,	,	PUNCT
fnp-6108	269	133	finland	finland	PROPN
fnp-6108	269	134	department	department	PROPN
fnp-6108	269	135	of	of	ADP
fnp-6108	269	136	clinical	clinical	ADJ
fnp-6108	269	137	pathology	pathology	NOUN
fnp-6108	269	138	,	,	PUNCT
fnp-6108	269	139	kuopio	kuopio	PROPN
fnp-6108	269	140	university	university	NOUN
fnp-6108	269	141	hospital	hospital	NOUN
fnp-6108	269	142	,	,	PUNCT
fnp-6108	269	143	kuopio	kuopio	PROPN
fnp-6108	269	144	,	,	PUNCT
fnp-6108	269	145	finland	finland	PROPN
fnp-6108	269	146	objectives	objective	NOUN
fnp-6108	269	147	:	:	PUNCT
fnp-6108	269	148	alzheimer	alzheimer	PROPN
fnp-6108	269	149	's	's	PART
fnp-6108	269	150	disease	disease	NOUN
fnp-6108	269	151	(	(	PUNCT
fnp-6108	269	152	ad)-related	ad)-relate	VERB
fnp-6108	269	153	pathologies	pathology	NOUN
fnp-6108	269	154	are	be	AUX
fnp-6108	269	155	frequent	frequent	ADJ
fnp-6108	269	156	comorbid	comorbid	NOUN
fnp-6108	269	157	findings	finding	NOUN
fnp-6108	269	158	in	in	ADP
fnp-6108	269	159	idiopathic	idiopathic	ADJ
fnp-6108	269	160	normal	normal	ADJ
fnp-6108	269	161	pressure	pressure	NOUN
fnp-6108	269	162	hydrocephalus	hydrocephalus	X
fnp-6108	269	163	(	(	PUNCT
fnp-6108	269	164	inph	inph	PROPN
fnp-6108	269	165	)	)	PUNCT
fnp-6108	269	166	.	.	PUNCT
fnp-6108	270	1	frontotemporal	frontotemporal	ADJ
fnp-6108	270	2	lobar	lobar	ADJ
fnp-6108	270	3	degeneration	degeneration	NOUN
fnp-6108	270	4	(	(	PUNCT
fnp-6108	270	5	ftld	ftld	ADJ
fnp-6108	270	6	)	)	PUNCT
fnp-6108	270	7	is	be	AUX
fnp-6108	270	8	another	another	DET
fnp-6108	270	9	important	important	ADJ
fnp-6108	270	10	but	but	CCONJ
fnp-6108	270	11	less	less	ADV
fnp-6108	270	12	studied	studied	ADJ
fnp-6108	270	13	potential	potential	ADJ
fnp-6108	270	14	comorbidity	comorbidity	NOUN
fnp-6108	270	15	,	,	PUNCT
fnp-6108	270	16	characterized	characterize	VERB
fnp-6108	270	17	by	by	ADP
fnp-6108	270	18	tdp-43	tdp-43	PROPN
fnp-6108	270	19	pathology	pathology	NOUN
fnp-6108	270	20	in	in	ADP
fnp-6108	270	21	approximately	approximately	ADV
fnp-6108	270	22	half	half	NOUN
fnp-6108	270	23	of	of	ADP
fnp-6108	270	24	the	the	DET
fnp-6108	270	25	cases	case	NOUN
fnp-6108	270	26	.	.	PUNCT
fnp-6108	271	1	to	to	ADP
fnp-6108	271	2	the	the	DET
fnp-6108	271	3	best	good	ADJ
fnp-6108	271	4	of	of	ADP
fnp-6108	271	5	our	our	PRON
fnp-6108	271	6	knowledge	knowledge	NOUN
fnp-6108	271	7	,	,	PUNCT
fnp-6108	271	8	tdp-43	tdp-43	PUNCT
fnp-6108	271	9	pathology	pathology	NOUN
fnp-6108	271	10	has	have	AUX
fnp-6108	271	11	not	not	PART
fnp-6108	271	12	been	be	AUX
fnp-6108	271	13	systematically	systematically	ADV
fnp-6108	271	14	studied	study	VERB
fnp-6108	271	15	in	in	ADP
fnp-6108	271	16	brain	brain	NOUN
fnp-6108	271	17	biopsies	biopsy	NOUN
fnp-6108	271	18	of	of	ADP
fnp-6108	271	19	patients	patient	NOUN
fnp-6108	271	20	with	with	ADP
fnp-6108	271	21	inph.our	inph.our	NOUN
fnp-6108	271	22	aim	aim	NOUN
fnp-6108	271	23	was	be	AUX
fnp-6108	271	24	to	to	PART
fnp-6108	271	25	evaluate	evaluate	VERB
fnp-6108	271	26	the	the	DET
fnp-6108	271	27	presence	presence	NOUN
fnp-6108	271	28	of	of	ADP
fnp-6108	271	29	tdp-43	tdp-43	PROPN
fnp-6108	271	30	pathology	pathology	PROPN
fnp-6108	271	31	in	in	ADP
fnp-6108	271	32	brain	brain	NOUN
fnp-6108	271	33	biopsies	biopsy	NOUN
fnp-6108	271	34	obtained	obtain	VERB
fnp-6108	271	35	during	during	ADP
fnp-6108	271	36	shunt	shunt	NOUN
fnp-6108	271	37	procedures	procedure	NOUN
fnp-6108	271	38	due	due	ADJ
fnp-6108	271	39	to	to	ADP
fnp-6108	271	40	inph	inph	NOUN
fnp-6108	271	41	.	.	PUNCT
fnp-6108	272	1	materials	material	NOUN
fnp-6108	272	2	and	and	CCONJ
fnp-6108	272	3	methods	method	NOUN
fnp-6108	272	4	:	:	PUNCT
fnp-6108	272	5	from	from	ADP
fnp-6108	272	6	2015	2015	NUM
fnp-6108	272	7	to	to	ADP
fnp-6108	272	8	the	the	DET
fnp-6108	272	9	end	end	NOUN
fnp-6108	272	10	of	of	ADP
fnp-6108	272	11	2023	2023	NUM
fnp-6108	272	12	,	,	PUNCT
fnp-6108	272	13	397	397	NUM
fnp-6108	272	14	patients	patient	NOUN
fnp-6108	272	15	with	with	ADP
fnp-6108	272	16	inph	inph	ADJ
fnp-6108	272	17	underwent	underwent	NOUN
fnp-6108	272	18	shunt	shunt	NOUN
fnp-6108	272	19	surgery	surgery	NOUN
fnp-6108	272	20	and	and	CCONJ
fnp-6108	272	21	right	right	ADJ
fnp-6108	272	22	frontal	frontal	ADJ
fnp-6108	272	23	brain	brain	NOUN
fnp-6108	272	24	biopsy	biopsy	NOUN
fnp-6108	272	25	at	at	ADP
fnp-6108	272	26	a	a	DET
fnp-6108	272	27	mean	mean	ADJ
fnp-6108	272	28	age	age	NOUN
fnp-6108	272	29	of	of	ADP
fnp-6108	272	30	74	74	NUM
fnp-6108	272	31	years	year	NOUN
fnp-6108	272	32	.	.	PUNCT
fnp-6108	273	1	brain	brain	NOUN
fnp-6108	273	2	biopsies	biopsy	NOUN
fnp-6108	273	3	were	be	AUX
fnp-6108	273	4	stained	stain	VERB
fnp-6108	273	5	for	for	ADP
fnp-6108	273	6	amyloid	amyloid	NOUN
fnp-6108	273	7	-	-	PUNCT
fnp-6108	273	8	β	β	X
fnp-6108	273	9	(	(	PUNCT
fnp-6108	273	10	6f/3d	6f/3d	NUM
fnp-6108	273	11	)	)	PUNCT
fnp-6108	273	12	,	,	PUNCT
fnp-6108	273	13	hyperphosphorylated	hyperphosphorylate	VERB
fnp-6108	273	14	tau	tau	PROPN
fnp-6108	273	15	(	(	PUNCT
fnp-6108	273	16	at8	at8	PROPN
fnp-6108	273	17	)	)	PUNCT
fnp-6108	273	18	,	,	PUNCT
fnp-6108	273	19	and	and	CCONJ
fnp-6108	273	20	tdp-43	tdp-43	PROPN
fnp-6108	273	21	(	(	PUNCT
fnp-6108	273	22	2e2	2e2	PROPN
fnp-6108	273	23	-	-	PUNCT
fnp-6108	273	24	d3	d3	PROPN
fnp-6108	273	25	)	)	PUNCT
fnp-6108	273	26	and	and	CCONJ
fnp-6108	273	27	evaluated	evaluate	VERB
fnp-6108	273	28	by	by	ADP
fnp-6108	273	29	a	a	DET
fnp-6108	273	30	neuropathologist	neuropathologist	NOUN
fnp-6108	273	31	.	.	PUNCT
fnp-6108	274	1	results	result	NOUN
fnp-6108	274	2	and	and	CCONJ
fnp-6108	274	3	conclusion	conclusion	NOUN
fnp-6108	274	4	:	:	PUNCT
fnp-6108	274	5	of	of	ADP
fnp-6108	274	6	the	the	DET
fnp-6108	274	7	397	397	NUM
fnp-6108	274	8	patients	patient	NOUN
fnp-6108	274	9	,	,	PUNCT
fnp-6108	274	10	16	16	NUM
fnp-6108	274	11	(	(	PUNCT
fnp-6108	274	12	4	4	NUM
fnp-6108	274	13	 	 	SPACE
fnp-6108	274	14	%	%	NOUN
fnp-6108	274	15	)	)	PUNCT
fnp-6108	274	16	had	have	VERB
fnp-6108	274	17	tdp-43	tdp-43	VERB
fnp-6108	274	18	positive	positive	ADJ
fnp-6108	274	19	neuronal	neuronal	ADJ
fnp-6108	274	20	cytoplasmic	cytoplasmic	ADJ
fnp-6108	274	21	inclusions	inclusion	NOUN
fnp-6108	274	22	or	or	CCONJ
fnp-6108	274	23	dystrophic	dystrophic	ADJ
fnp-6108	274	24	neurites	neurite	NOUN
fnp-6108	274	25	,	,	PUNCT
fnp-6108	274	26	with	with	ADP
fnp-6108	274	27	a	a	DET
fnp-6108	274	28	mean	mean	ADJ
fnp-6108	274	29	age	age	NOUN
fnp-6108	274	30	of	of	ADP
fnp-6108	274	31	74	74	NUM
fnp-6108	274	32	.	.	PUNCT
fnp-6108	275	1	of	of	ADP
fnp-6108	275	2	these	these	PRON
fnp-6108	275	3	,	,	PUNCT
fnp-6108	275	4	six	six	NUM
fnp-6108	275	5	patients	patient	NOUN
fnp-6108	275	6	had	have	VERB
fnp-6108	275	7	additional	additional	ADJ
fnp-6108	275	8	aβ	aβ	PRON
fnp-6108	276	1	pathology	pathology	NOUN
fnp-6108	277	1	(	(	PUNCT
fnp-6108	278	1	aβ+tdp-43	aβ+tdp-43	PROPN
fnp-6108	278	2	)	)	PUNCT
fnp-6108	279	1	and	and	CCONJ
fnp-6108	279	2	two	two	NUM
fnp-6108	279	3	had	have	VERB
fnp-6108	279	4	additional	additional	ADJ
fnp-6108	279	5	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-6108	279	6	tau	tau	PROPN
fnp-6108	279	7	pathology	pathology	NOUN
fnp-6108	279	8	(	(	PUNCT
fnp-6108	279	9	tau+tdp-43	tau+tdp-43	PROPN
fnp-6108	279	10	)	)	PUNCT
fnp-6108	279	11	.	.	PUNCT
fnp-6108	280	1	tdp-43	tdp-43	PROPN
fnp-6108	280	2	appears	appear	VERB
fnp-6108	280	3	to	to	PART
fnp-6108	280	4	be	be	AUX
fnp-6108	280	5	rather	rather	ADV
fnp-6108	280	6	rare	rare	ADJ
fnp-6108	280	7	but	but	CCONJ
fnp-6108	280	8	potentially	potentially	ADV
fnp-6108	280	9	clinically	clinically	ADV
fnp-6108	280	10	highly	highly	ADV
fnp-6108	280	11	relevant	relevant	ADJ
fnp-6108	280	12	comorbid	comorbid	NOUN
fnp-6108	280	13	pathology	pathology	NOUN
fnp-6108	280	14	in	in	ADP
fnp-6108	280	15	inph	inph	PROPN
fnp-6108	280	16	.	.	PUNCT
fnp-6108	280	17	  	  	SPACE
fnp-6108	281	1	free	free	ADJ
fnp-6108	281	2	neuropathol	neuropathol	NOUN
fnp-6108	281	3	5:30:29	5:30:29	NUM
fnp-6108	281	4	cns	cns	NOUN
fnp-6108	281	5	amyloid	amyloid	NOUN
fnp-6108	281	6	patterns	pattern	NOUN
fnp-6108	281	7	in	in	ADP
fnp-6108	281	8	aging	age	VERB
fnp-6108	281	9	canines	canine	NOUN
fnp-6108	281	10	–	–	PUNCT
fnp-6108	281	11	a	a	DET
fnp-6108	281	12	pilotstudy	pilotstudy	NOUN
fnp-6108	281	13	regarding	regard	VERB
fnp-6108	281	14	neuropathology	neuropathology	NOUN
fnp-6108	281	15	in	in	ADP
fnp-6108	281	16	canine	canine	NOUN
fnp-6108	281	17	cognitive	cognitive	ADJ
fnp-6108	281	18	dysfunction	dysfunction	NOUN
fnp-6108	281	19	pernilla	pernilla	NOUN
fnp-6108	281	20	syrjä1	syrjä1	PROPN
fnp-6108	281	21	,	,	PUNCT
fnp-6108	281	22	linda	linda	PROPN
fnp-6108	281	23	rasmus1	rasmus1	PROPN
fnp-6108	281	24	,	,	PUNCT
fnp-6108	281	25	tarja	tarja	PROPN
fnp-6108	281	26	pääkkönen2	pääkkönen2	PROPN
fnp-6108	281	27	department	department	PROPN
fnp-6108	281	28	of	of	ADP
fnp-6108	281	29	veterinary	veterinary	ADJ
fnp-6108	281	30	biosciences	bioscience	NOUN
fnp-6108	281	31	,	,	PUNCT
fnp-6108	281	32	veterinary	veterinary	ADJ
fnp-6108	281	33	pathology	pathology	NOUN
fnp-6108	281	34	and	and	CCONJ
fnp-6108	281	35	parasitology	parasitology	NOUN
fnp-6108	281	36	,	,	PUNCT
fnp-6108	281	37	faculty	faculty	NOUN
fnp-6108	281	38	of	of	ADP
fnp-6108	281	39	veterinary	veterinary	ADJ
fnp-6108	281	40	medicine	medicine	NOUN
fnp-6108	281	41	,	,	PUNCT
fnp-6108	281	42	university	university	PROPN
fnp-6108	281	43	of	of	ADP
fnp-6108	281	44	helsinki	helsinki	PROPN
fnp-6108	281	45	,	,	PUNCT
fnp-6108	281	46	helsinki	helsinki	PROPN
fnp-6108	281	47	,	,	PUNCT
fnp-6108	281	48	finland	finland	PROPN
fnp-6108	281	49	department	department	PROPN
fnp-6108	281	50	of	of	ADP
fnp-6108	281	51	equine	equine	NOUN
fnp-6108	281	52	and	and	CCONJ
fnp-6108	281	53	small	small	ADJ
fnp-6108	281	54	animal	animal	NOUN
fnp-6108	281	55	medicine	medicine	NOUN
fnp-6108	281	56	,	,	PUNCT
fnp-6108	281	57	faculty	faculty	NOUN
fnp-6108	281	58	of	of	ADP
fnp-6108	281	59	veterinary	veterinary	ADJ
fnp-6108	281	60	medicine	medicine	NOUN
fnp-6108	281	61	,	,	PUNCT
fnp-6108	281	62	university	university	PROPN
fnp-6108	281	63	of	of	ADP
fnp-6108	281	64	helsinki	helsinki	PROPN
fnp-6108	281	65	helsinki	helsinki	PROPN
fnp-6108	281	66	,	,	PUNCT
fnp-6108	281	67	finland	finland	PROPN
fnp-6108	281	68	the	the	DET
fnp-6108	281	69	objective	objective	NOUN
fnp-6108	281	70	of	of	ADP
fnp-6108	281	71	this	this	DET
fnp-6108	281	72	pilot	pilot	NOUN
fnp-6108	281	73	study	study	NOUN
fnp-6108	281	74	was	be	AUX
fnp-6108	281	75	to	to	PART
fnp-6108	281	76	characterize	characterize	VERB
fnp-6108	281	77	cns	cns	NOUN
fnp-6108	281	78	amyloid	amyloid	NOUN
fnp-6108	281	79	deposit	deposit	NOUN
fnp-6108	281	80	patterns	pattern	NOUN
fnp-6108	281	81	in	in	ADP
fnp-6108	281	82	aging	age	VERB
fnp-6108	281	83	canines	canine	NOUN
fnp-6108	281	84	,	,	PUNCT
fnp-6108	281	85	to	to	PART
fnp-6108	281	86	enable	enable	VERB
fnp-6108	281	87	correlating	correlate	VERB
fnp-6108	281	88	them	they	PRON
fnp-6108	281	89	with	with	ADP
fnp-6108	281	90	canine	canine	NOUN
fnp-6108	281	91	cognitive	cognitive	ADJ
fnp-6108	281	92	dysfunction	dysfunction	NOUN
fnp-6108	281	93	(	(	PUNCT
fnp-6108	281	94	ccd	ccd	NOUN
fnp-6108	281	95	)	)	PUNCT
fnp-6108	281	96	.	.	PUNCT
fnp-6108	282	1	the	the	DET
fnp-6108	282	2	pilot	pilot	NOUN
fnp-6108	282	3	starts	start	VERB
fnp-6108	282	4	a	a	DET
fnp-6108	282	5	larger	large	ADJ
fnp-6108	282	6	study	study	NOUN
fnp-6108	282	7	investigating	investigate	VERB
fnp-6108	282	8	cns	cns	NOUN
fnp-6108	282	9	amyloid	amyloid	NOUN
fnp-6108	282	10	deposition	deposition	NOUN
fnp-6108	282	11	,	,	PUNCT
fnp-6108	282	12	tauopathy	tauopathy	ADJ
fnp-6108	282	13	,	,	PUNCT
fnp-6108	282	14	microglial	microglial	ADJ
fnp-6108	282	15	changes	change	NOUN
fnp-6108	282	16	,	,	PUNCT
fnp-6108	282	17	blood	blood	NOUN
fnp-6108	282	18	-	-	PUNCT
fnp-6108	282	19	derived	derive	VERB
fnp-6108	282	20	macrophage	macrophage	ADJ
fnp-6108	282	21	response	response	NOUN
fnp-6108	282	22	,	,	PUNCT
fnp-6108	282	23	microbleeds	microbleed	NOUN
fnp-6108	282	24	and	and	CCONJ
fnp-6108	282	25	extraneural	extraneural	ADJ
fnp-6108	282	26	amyloid	amyloid	NOUN
fnp-6108	282	27	of	of	ADP
fnp-6108	282	28	aging	age	VERB
fnp-6108	282	29	dogs	dog	NOUN
fnp-6108	282	30	with	with	ADP
fnp-6108	282	31	ccd	ccd	NOUN
fnp-6108	282	32	in	in	ADP
fnp-6108	282	33	comparison	comparison	NOUN
fnp-6108	282	34	to	to	ADP
fnp-6108	282	35	aging	age	VERB
fnp-6108	282	36	dogs	dog	NOUN
fnp-6108	282	37	without	without	ADP
fnp-6108	282	38	ccd	ccd	PROPN
fnp-6108	282	39	.	.	PUNCT
fnp-6108	283	1	dogs	dog	NOUN
fnp-6108	283	2	share	share	VERB
fnp-6108	283	3	similar	similar	ADJ
fnp-6108	283	4	environment	environment	NOUN
fnp-6108	283	5	,	,	PUNCT
fnp-6108	283	6	basic	basic	ADJ
fnp-6108	283	7	neuropathological	neuropathological	ADJ
fnp-6108	283	8	mechanisms	mechanism	NOUN
fnp-6108	283	9	,	,	PUNCT
fnp-6108	283	10	and	and	CCONJ
fnp-6108	283	11	amyloid	amyloid	NOUN
fnp-6108	283	12	type	type	NOUN
fnp-6108	283	13	as	as	ADP
fnp-6108	283	14	man	man	NOUN
fnp-6108	283	15	.	.	PUNCT
fnp-6108	284	1	therefore	therefore	ADV
fnp-6108	284	2	,	,	PUNCT
fnp-6108	284	3	insights	insight	NOUN
fnp-6108	284	4	into	into	ADP
fnp-6108	284	5	why	why	SCONJ
fnp-6108	284	6	dogs	dog	NOUN
fnp-6108	284	7	do	do	AUX
fnp-6108	284	8	not	not	PART
fnp-6108	284	9	develop	develop	VERB
fnp-6108	284	10	mature	mature	ADJ
fnp-6108	284	11	ad	ad	NOUN
fnp-6108	284	12	pathology	pathology	NOUN
fnp-6108	284	13	would	would	AUX
fnp-6108	284	14	be	be	AUX
fnp-6108	284	15	of	of	ADP
fnp-6108	284	16	comparative	comparative	ADJ
fnp-6108	284	17	value	value	NOUN
fnp-6108	284	18	.	.	PUNCT
fnp-6108	285	1	the	the	DET
fnp-6108	285	2	formalin	formalin	NOUN
fnp-6108	285	3	-	-	PUNCT
fnp-6108	285	4	fixed	fix	VERB
fnp-6108	285	5	frontal	frontal	ADJ
fnp-6108	285	6	cortex	cortex	NOUN
fnp-6108	285	7	and	and	CCONJ
fnp-6108	285	8	hippocampus	hippocampus	NOUN
fnp-6108	285	9	from	from	ADP
fnp-6108	285	10	twenty	twenty	NUM
fnp-6108	285	11	dogs	dog	NOUN
fnp-6108	285	12	,	,	PUNCT
fnp-6108	285	13	average	average	ADJ
fnp-6108	285	14	11.2	11.2	NUM
fnp-6108	285	15	years	year	NOUN
fnp-6108	285	16	old	old	ADJ
fnp-6108	285	17	(	(	PUNCT
fnp-6108	285	18	sd	sd	ADP
fnp-6108	285	19	2.2	2.2	NUM
fnp-6108	285	20	years	year	NOUN
fnp-6108	285	21	)	)	PUNCT
fnp-6108	285	22	were	be	AUX
fnp-6108	285	23	retrieved	retrieve	VERB
fnp-6108	285	24	in	in	ADP
fnp-6108	285	25	retrospect	retrospect	NOUN
fnp-6108	285	26	from	from	ADP
fnp-6108	285	27	the	the	DET
fnp-6108	285	28	patient	patient	ADJ
fnp-6108	285	29	archives	archive	NOUN
fnp-6108	285	30	of	of	ADP
fnp-6108	285	31	the	the	DET
fnp-6108	285	32	section	section	NOUN
fnp-6108	285	33	for	for	ADP
fnp-6108	285	34	pathology	pathology	NOUN
fnp-6108	285	35	,	,	PUNCT
fnp-6108	285	36	faculty	faculty	NOUN
fnp-6108	285	37	of	of	ADP
fnp-6108	285	38	veterinary	veterinary	ADJ
fnp-6108	285	39	medicine	medicine	NOUN
fnp-6108	285	40	,	,	PUNCT
fnp-6108	285	41	university	university	NOUN
fnp-6108	285	42	of	of	ADP
fnp-6108	285	43	helsinki	helsinki	PROPN
fnp-6108	285	44	and	and	CCONJ
fnp-6108	285	45	stained	stain	VERB
fnp-6108	285	46	by	by	ADP
fnp-6108	285	47	ihc	ihc	PROPN
fnp-6108	285	48	for	for	ADP
fnp-6108	285	49	amyloid	amyloid	NOUN
fnp-6108	285	50	beta	beta	NOUN
fnp-6108	285	51	.	.	PUNCT
fnp-6108	286	1	amyloid	amyloid	NOUN
fnp-6108	286	2	was	be	AUX
fnp-6108	286	3	present	present	ADJ
fnp-6108	286	4	in	in	ADP
fnp-6108	286	5	the	the	DET
fnp-6108	286	6	cortical	cortical	ADJ
fnp-6108	286	7	neuropil	neuropil	NOUN
fnp-6108	286	8	,	,	PUNCT
fnp-6108	286	9	tunica	tunica	PROPN
fnp-6108	286	10	externa	externa	NOUN
fnp-6108	286	11	and	and	CCONJ
fnp-6108	286	12	media	medium	NOUN
fnp-6108	286	13	of	of	ADP
fnp-6108	286	14	meningeal	meningeal	ADJ
fnp-6108	286	15	vessels	vessel	NOUN
fnp-6108	286	16	,	,	PUNCT
fnp-6108	286	17	and	and	CCONJ
fnp-6108	286	18	in	in	ADP
fnp-6108	286	19	meningeal	meningeal	ADJ
fnp-6108	286	20	macrophages	macrophage	NOUN
fnp-6108	286	21	in	in	ADP
fnp-6108	286	22	11/20	11/20	NUM
fnp-6108	286	23	dogs	dog	NOUN
fnp-6108	286	24	.	.	PUNCT
fnp-6108	287	1	the	the	DET
fnp-6108	287	2	hippocampal	hippocampal	ADJ
fnp-6108	287	3	perforant	perforant	ADJ
fnp-6108	287	4	pathways	pathway	NOUN
fnp-6108	287	5	contained	contain	VERB
fnp-6108	287	6	amyloid	amyloid	NOUN
fnp-6108	287	7	in	in	ADP
fnp-6108	287	8	eight	eight	NUM
fnp-6108	287	9	of	of	ADP
fnp-6108	287	10	these	these	DET
fnp-6108	287	11	eleven	eleven	NUM
fnp-6108	287	12	dogs	dog	NOUN
fnp-6108	287	13	.	.	PUNCT
fnp-6108	288	1	cortical	cortical	ADJ
fnp-6108	288	2	capillary	capillary	ADJ
fnp-6108	288	3	amyloid	amyloid	NOUN
fnp-6108	288	4	deposits	deposit	NOUN
fnp-6108	288	5	were	be	AUX
fnp-6108	288	6	a	a	DET
fnp-6108	288	7	main	main	ADJ
fnp-6108	288	8	feature	feature	NOUN
fnp-6108	288	9	in	in	ADP
fnp-6108	288	10	6/20	6/20	NUM
fnp-6108	288	11	dogs	dog	NOUN
fnp-6108	288	12	.	.	PUNCT
fnp-6108	289	1	four	four	NUM
fnp-6108	289	2	dogs	dog	NOUN
fnp-6108	289	3	did	do	AUX
fnp-6108	289	4	not	not	PART
fnp-6108	289	5	show	show	VERB
fnp-6108	289	6	cns	cns	NOUN
fnp-6108	289	7	amyloid	amyloid	NOUN
fnp-6108	289	8	.	.	PUNCT
fnp-6108	290	1	aging	age	VERB
fnp-6108	290	2	dogs	dog	NOUN
fnp-6108	290	3	develop	develop	VERB
fnp-6108	290	4	amyloid	amyloid	NOUN
fnp-6108	290	5	deposits	deposit	NOUN
fnp-6108	290	6	at	at	ADP
fnp-6108	290	7	specific	specific	ADJ
fnp-6108	290	8	locations	location	NOUN
fnp-6108	290	9	in	in	ADP
fnp-6108	290	10	the	the	DET
fnp-6108	290	11	brain	brain	NOUN
fnp-6108	290	12	,	,	PUNCT
fnp-6108	290	13	in	in	ADP
fnp-6108	290	14	patterns	pattern	NOUN
fnp-6108	290	15	partially	partially	ADV
fnp-6108	290	16	comparable	comparable	ADJ
fnp-6108	290	17	to	to	ADP
fnp-6108	290	18	those	those	PRON
fnp-6108	290	19	of	of	ADP
fnp-6108	290	20	amyloid	amyloid	NOUN
fnp-6108	290	21	angiopathy	angiopathy	ADJ
fnp-6108	290	22	in	in	ADP
fnp-6108	290	23	man	man	NOUN
fnp-6108	290	24	.	.	PUNCT
fnp-6108	291	1	deposits	deposit	NOUN
fnp-6108	291	2	reminiscent	reminiscent	ADJ
fnp-6108	291	3	of	of	ADP
fnp-6108	291	4	dense	dense	ADJ
fnp-6108	291	5	core	core	NOUN
fnp-6108	291	6	plaques	plaque	NOUN
fnp-6108	291	7	were	be	AUX
fnp-6108	291	8	not	not	PART
fnp-6108	291	9	detected	detect	VERB
fnp-6108	291	10	in	in	ADP
fnp-6108	291	11	this	this	DET
fnp-6108	291	12	cohort	cohort	NOUN
fnp-6108	291	13	,	,	PUNCT
fnp-6108	291	14	consistent	consistent	ADJ
fnp-6108	291	15	with	with	ADP
fnp-6108	291	16	what	what	PRON
fnp-6108	291	17	is	be	AUX
fnp-6108	291	18	currently	currently	ADV
fnp-6108	291	19	known	know	VERB
fnp-6108	291	20	in	in	ADP
fnp-6108	291	21	dogs	dog	NOUN
fnp-6108	291	22	.	.	PUNCT
fnp-6108	292	1	this	this	PRON
fnp-6108	292	2	provides	provide	VERB
fnp-6108	292	3	a	a	DET
fnp-6108	292	4	starting	starting	NOUN
fnp-6108	292	5	point	point	NOUN
fnp-6108	292	6	to	to	PART
fnp-6108	292	7	assess	assess	VERB
fnp-6108	292	8	if	if	SCONJ
fnp-6108	292	9	a	a	DET
fnp-6108	292	10	distinct	distinct	ADJ
fnp-6108	292	11	amyloid	amyloid	NOUN
fnp-6108	292	12	deposition	deposition	NOUN
fnp-6108	292	13	pattern	pattern	NOUN
fnp-6108	292	14	is	be	AUX
fnp-6108	292	15	associated	associate	VERB
fnp-6108	292	16	with	with	ADP
fnp-6108	292	17	clinical	clinical	ADJ
fnp-6108	292	18	ccd	ccd	NOUN
fnp-6108	292	19	and	and	CCONJ
fnp-6108	292	20	to	to	PART
fnp-6108	292	21	further	far	ADV
fnp-6108	292	22	elucidate	elucidate	VERB
fnp-6108	292	23	the	the	DET
fnp-6108	292	24	neuropathology	neuropathology	NOUN
fnp-6108	292	25	of	of	ADP
fnp-6108	292	26	cognitive	cognitive	ADJ
fnp-6108	292	27	decline	decline	NOUN
fnp-6108	292	28	in	in	ADP
fnp-6108	292	29	dogs	dog	NOUN
fnp-6108	292	30	.	.	PUNCT
fnp-6108	292	31	  	  	SPACE
fnp-6108	293	1	free	free	ADJ
fnp-6108	293	2	neuropathol	neuropathol	NOUN
fnp-6108	293	3	5:30:30–31	5:30:30–31	NUM
fnp-6108	293	4	common	common	ADJ
fnp-6108	293	5	associations	association	NOUN
fnp-6108	293	6	of	of	ADP
fnp-6108	293	7	transcranial	transcranial	ADJ
fnp-6108	293	8	magnetic	magnetic	ADJ
fnp-6108	293	9	stimulation	stimulation	NOUN
fnp-6108	293	10	(	(	PUNCT
fnp-6108	293	11	tms	tms	PROPN
fnp-6108	293	12	)	)	PUNCT
fnp-6108	293	13	parameters	parameter	NOUN
fnp-6108	293	14	and	and	CCONJ
fnp-6108	293	15	behavioral	behavioral	ADJ
fnp-6108	293	16	symptoms	symptom	NOUN
fnp-6108	293	17	in	in	ADP
fnp-6108	293	18	different	different	ADJ
fnp-6108	293	19	neurocognitive	neurocognitive	ADJ
fnp-6108	293	20	diseases	disease	NOUN
fnp-6108	293	21	matti	matti	PROPN
fnp-6108	293	22	tyrväinen1	tyrväinen1	PROPN
fnp-6108	293	23	,	,	PUNCT
fnp-6108	293	24	laura	laura	PROPN
fnp-6108	293	25	säisänen1,2,3	säisänen1,2,3	PROPN
fnp-6108	293	26	,	,	PUNCT
fnp-6108	293	27	jelena	jelena	PROPN
fnp-6108	293	28	hyppönen1,3	hyppönen1,3	PROPN
fnp-6108	293	29	,	,	PUNCT
fnp-6108	293	30	sara	sara	PROPN
fnp-6108	293	31	määttä3	määttä3	PROPN
fnp-6108	293	32	,	,	PUNCT
fnp-6108	293	33	kaarlo	kaarlo	PROPN
fnp-6108	293	34	ylimäki2	ylimäki2	PROPN
fnp-6108	293	35	,	,	PUNCT
fnp-6108	293	36	kasper	kasper	PROPN
fnp-6108	293	37	katisko2	katisko2	PROPN
fnp-6108	293	38	,	,	PUNCT
fnp-6108	293	39	johanna	johanna	PROPN
fnp-6108	293	40	kruger4,5,6	kruger4,5,6	PROPN
fnp-6108	293	41	,	,	PUNCT
fnp-6108	293	42	noora	noora	PROPN
fnp-6108	293	43	-	-	PUNCT
fnp-6108	293	44	maria	maria	PROPN
fnp-6108	293	45	suhonen4,5,6	suhonen4,5,6	PROPN
fnp-6108	293	46	,	,	PUNCT
fnp-6108	293	47	päivi	päivi	PROPN
fnp-6108	293	48	hartikainen7	hartikainen7	PROPN
fnp-6108	293	49	,	,	PUNCT
fnp-6108	293	50	barbara	barbara	PROPN
fnp-6108	293	51	borroni8	borroni8	PROPN
fnp-6108	293	52	,	,	PUNCT
fnp-6108	293	53	annakaisa	annakaisa	PROPN
fnp-6108	293	54	haapasalo9	haapasalo9	PROPN
fnp-6108	293	55	,	,	PUNCT
fnp-6108	293	56	esa	esa	PROPN
fnp-6108	293	57	mervaala1,3	mervaala1,3	PROPN
fnp-6108	293	58	,	,	PUNCT
fnp-6108	293	59	eino	eino	PROPN
fnp-6108	293	60	solje2,7	solje2,7	PROPN
fnp-6108	293	61	institute	institute	PROPN
fnp-6108	293	62	of	of	ADP
fnp-6108	293	63	clinical	clinical	ADJ
fnp-6108	293	64	medicine	medicine	NOUN
fnp-6108	293	65	–	–	PUNCT
fnp-6108	293	66	clinical	clinical	ADJ
fnp-6108	293	67	neurophysiology	neurophysiology	NOUN
fnp-6108	293	68	,	,	PUNCT
fnp-6108	293	69	university	university	NOUN
fnp-6108	293	70	of	of	ADP
fnp-6108	293	71	eastern	eastern	PROPN
fnp-6108	293	72	finland	finland	PROPN
fnp-6108	293	73	,	,	PUNCT
fnp-6108	293	74	kuopio	kuopio	PROPN
fnp-6108	293	75	,	,	PUNCT
fnp-6108	293	76	finland	finland	PROPN
fnp-6108	293	77	institute	institute	PROPN
fnp-6108	293	78	of	of	ADP
fnp-6108	293	79	clinical	clinical	ADJ
fnp-6108	293	80	medicine	medicine	NOUN
fnp-6108	293	81	–	–	PUNCT
fnp-6108	293	82	neurology	neurology	NOUN
fnp-6108	293	83	,	,	PUNCT
fnp-6108	293	84	university	university	NOUN
fnp-6108	293	85	of	of	ADP
fnp-6108	293	86	eastern	eastern	PROPN
fnp-6108	293	87	finland	finland	PROPN
fnp-6108	293	88	,	,	PUNCT
fnp-6108	293	89	kuopio	kuopio	PROPN
fnp-6108	293	90	,	,	PUNCT
fnp-6108	293	91	finland	finland	PROPN
fnp-6108	293	92	department	department	PROPN
fnp-6108	293	93	of	of	ADP
fnp-6108	293	94	clinical	clinical	ADJ
fnp-6108	293	95	neurophysiology	neurophysiology	NOUN
fnp-6108	293	96	,	,	PUNCT
fnp-6108	293	97	kuopio	kuopio	NOUN
fnp-6108	293	98	university	university	NOUN
fnp-6108	293	99	hospital	hospital	NOUN
fnp-6108	293	100	,	,	PUNCT
fnp-6108	293	101	kuopio	kuopio	PROPN
fnp-6108	293	102	,	,	PUNCT
fnp-6108	293	103	finland	finland	PROPN
fnp-6108	293	104	research	research	NOUN
fnp-6108	293	105	unit	unit	NOUN
fnp-6108	293	106	of	of	ADP
fnp-6108	293	107	clinical	clinical	ADJ
fnp-6108	293	108	medicine	medicine	NOUN
fnp-6108	293	109	,	,	PUNCT
fnp-6108	293	110	neurology	neurology	NOUN
fnp-6108	293	111	,	,	PUNCT
fnp-6108	293	112	university	university	NOUN
fnp-6108	293	113	of	of	ADP
fnp-6108	293	114	oulu	oulu	PROPN
fnp-6108	293	115	,	,	PUNCT
fnp-6108	293	116	oulu	oulu	PROPN
fnp-6108	293	117	,	,	PUNCT
fnp-6108	293	118	finland	finland	PROPN
fnp-6108	293	119	mrc	mrc	PROPN
fnp-6108	293	120	,	,	PUNCT
fnp-6108	293	121	oulu	oulu	PROPN
fnp-6108	293	122	university	university	PROPN
fnp-6108	293	123	hospital	hospital	NOUN
fnp-6108	293	124	,	,	PUNCT
fnp-6108	293	125	oulu	oulu	PROPN
fnp-6108	293	126	,	,	PUNCT
fnp-6108	293	127	finland	finland	PROPN
fnp-6108	293	128	neurocenter	neurocenter	PROPN
fnp-6108	293	129	,	,	PUNCT
fnp-6108	293	130	neurology	neurology	NOUN
fnp-6108	293	131	,	,	PUNCT
fnp-6108	293	132	oulu	oulu	PROPN
fnp-6108	293	133	university	university	PROPN
fnp-6108	293	134	hospital	hospital	NOUN
fnp-6108	293	135	,	,	PUNCT
fnp-6108	293	136	oulu	oulu	PROPN
fnp-6108	293	137	,	,	PUNCT
fnp-6108	293	138	finland	finland	PROPN
fnp-6108	293	139	neuro	neuro	PROPN
fnp-6108	293	140	center	center	PROPN
fnp-6108	293	141	–	–	PUNCT
fnp-6108	293	142	neurology	neurology	NOUN
fnp-6108	293	143	,	,	PUNCT
fnp-6108	293	144	kuopio	kuopio	PROPN
fnp-6108	293	145	university	university	NOUN
fnp-6108	293	146	hospital	hospital	NOUN
fnp-6108	293	147	,	,	PUNCT
fnp-6108	293	148	kuopio	kuopio	PROPN
fnp-6108	293	149	,	,	PUNCT
fnp-6108	293	150	finland	finland	PROPN
fnp-6108	293	151	neurology	neurology	NOUN
fnp-6108	293	152	unit	unit	NOUN
fnp-6108	293	153	,	,	PUNCT
fnp-6108	293	154	centre	centre	NOUN
fnp-6108	293	155	for	for	ADP
fnp-6108	293	156	neurodegenerative	neurodegenerative	ADJ
fnp-6108	293	157	disorders	disorder	NOUN
fnp-6108	293	158	,	,	PUNCT
fnp-6108	293	159	department	department	NOUN
fnp-6108	293	160	of	of	ADP
fnp-6108	293	161	clinical	clinical	ADJ
fnp-6108	293	162	and	and	CCONJ
fnp-6108	293	163	experimental	experimental	ADJ
fnp-6108	293	164	sciences	science	NOUN
fnp-6108	293	165	,	,	PUNCT
fnp-6108	293	166	university	university	NOUN
fnp-6108	293	167	of	of	ADP
fnp-6108	293	168	brescia	brescia	PROPN
fnp-6108	293	169	,	,	PUNCT
fnp-6108	293	170	brescia	brescia	PROPN
fnp-6108	293	171	,	,	PUNCT
fnp-6108	293	172	italy	italy	PROPN
fnp-6108	293	173	a.i	a.i	PROPN
fnp-6108	293	174	.	.	PROPN
fnp-6108	293	175	virtanen	virtanen	PROPN
fnp-6108	293	176	institute	institute	PROPN
fnp-6108	293	177	for	for	ADP
fnp-6108	293	178	molecular	molecular	ADJ
fnp-6108	293	179	sciences	science	NOUN
fnp-6108	293	180	–	–	PUNCT
fnp-6108	293	181	university	university	NOUN
fnp-6108	293	182	of	of	ADP
fnp-6108	293	183	eastern	eastern	PROPN
fnp-6108	293	184	finland	finland	PROPN
fnp-6108	293	185	,	,	PUNCT
fnp-6108	293	186	kuopio	kuopio	PROPN
fnp-6108	293	187	,	,	PUNCT
fnp-6108	293	188	finland	finland	PROPN
fnp-6108	293	189	state	state	NOUN
fnp-6108	293	190	of	of	ADP
fnp-6108	293	191	the	the	DET
fnp-6108	293	192	art	art	NOUN
fnp-6108	293	193	:	:	PUNCT
fnp-6108	293	194	behavioral	behavioral	ADJ
fnp-6108	293	195	changes	change	NOUN
fnp-6108	293	196	are	be	AUX
fnp-6108	293	197	characteristic	characteristic	ADJ
fnp-6108	293	198	for	for	ADP
fnp-6108	293	199	frontotemporal	frontotemporal	ADJ
fnp-6108	293	200	dementia	dementia	NOUN
fnp-6108	293	201	(	(	PUNCT
fnp-6108	293	202	ftd	ftd	NOUN
fnp-6108	293	203	)	)	PUNCT
fnp-6108	293	204	and	and	CCONJ
fnp-6108	293	205	other	other	ADJ
fnp-6108	293	206	forms	form	NOUN
fnp-6108	293	207	of	of	ADP
fnp-6108	293	208	neurocognitive	neurocognitive	ADJ
fnp-6108	293	209	disorders	disorder	NOUN
fnp-6108	293	210	.	.	PUNCT
fnp-6108	294	1	transcranial	transcranial	ADJ
fnp-6108	294	2	magnetic	magnetic	ADJ
fnp-6108	294	3	stimulation	stimulation	NOUN
fnp-6108	294	4	(	(	PUNCT
fnp-6108	294	5	tms	tms	PROPN
fnp-6108	294	6	)	)	PUNCT
fnp-6108	294	7	can	can	AUX
fnp-6108	294	8	be	be	AUX
fnp-6108	294	9	used	use	VERB
fnp-6108	294	10	to	to	PART
fnp-6108	294	11	non	non	ADJ
fnp-6108	294	12	-	-	ADJ
fnp-6108	294	13	invasively	invasively	ADV
fnp-6108	294	14	assess	assess	NOUN
fnp-6108	294	15	disease	disease	NOUN
fnp-6108	294	16	-	-	PUNCT
fnp-6108	294	17	specific	specific	ADJ
fnp-6108	294	18	changes	change	NOUN
fnp-6108	294	19	in	in	ADP
fnp-6108	294	20	inhibitory	inhibitory	ADJ
fnp-6108	294	21	and	and	CCONJ
fnp-6108	294	22	excitatory	excitatory	NOUN
fnp-6108	294	23	processes	process	NOUN
fnp-6108	294	24	.	.	PUNCT
fnp-6108	295	1	we	we	PRON
fnp-6108	295	2	determined	determine	VERB
fnp-6108	295	3	the	the	DET
fnp-6108	295	4	association	association	NOUN
fnp-6108	295	5	of	of	ADP
fnp-6108	295	6	tms	tms	PROPN
fnp-6108	295	7	variables	variable	NOUN
fnp-6108	295	8	with	with	ADP
fnp-6108	295	9	ftd	ftd	NOUN
fnp-6108	295	10	-	-	PUNCT
fnp-6108	295	11	like	like	ADJ
fnp-6108	295	12	personality	personality	NOUN
fnp-6108	295	13	and	and	CCONJ
fnp-6108	295	14	behavioral	behavioral	ADJ
fnp-6108	295	15	changes	change	NOUN
fnp-6108	295	16	,	,	PUNCT
fnp-6108	295	17	captured	capture	VERB
fnp-6108	295	18	using	use	VERB
fnp-6108	295	19	the	the	DET
fnp-6108	295	20	modified	modify	VERB
fnp-6108	295	21	frontal	frontal	ADJ
fnp-6108	295	22	behavior	behavior	NOUN
fnp-6108	295	23	inventory	inventory	NOUN
fnp-6108	295	24	(	(	PUNCT
fnp-6108	295	25	fbi	fbi	PROPN
fnp-6108	295	26	-	-	PUNCT
fnp-6108	295	27	mod	mod	NOUN
fnp-6108	295	28	)	)	PUNCT
fnp-6108	295	29	questionnaire	questionnaire	NOUN
fnp-6108	295	30	,	,	PUNCT
fnp-6108	295	31	independently	independently	ADV
fnp-6108	295	32	from	from	ADP
fnp-6108	295	33	diagnostic	diagnostic	ADJ
fnp-6108	295	34	classification	classification	NOUN
fnp-6108	295	35	.	.	PUNCT
fnp-6108	296	1	methodology	methodology	NOUN
fnp-6108	296	2	:	:	PUNCT
fnp-6108	296	3	in	in	ADP
fnp-6108	296	4	total	total	ADJ
fnp-6108	296	5	,	,	PUNCT
fnp-6108	296	6	103	103	NUM
fnp-6108	296	7	patients	patient	NOUN
fnp-6108	296	8	(	(	PUNCT
fnp-6108	296	9	35	35	NUM
fnp-6108	296	10	 	 	SPACE
fnp-6108	296	11	%	%	NOUN
fnp-6108	296	12	female	female	NOUN
fnp-6108	296	13	,	,	PUNCT
fnp-6108	296	14	mean	mean	VERB
fnp-6108	296	15	age	age	NOUN
fnp-6108	296	16	68	68	NUM
fnp-6108	296	17	years	year	NOUN
fnp-6108	296	18	,	,	PUNCT
fnp-6108	296	19	28	28	NUM
fnp-6108	296	20	ftd	ftd	NOUN
fnp-6108	296	21	or	or	CCONJ
fnp-6108	296	22	ftd	ftd	PROPN
fnp-6108	296	23	-	-	PUNCT
fnp-6108	296	24	like	like	ADJ
fnp-6108	296	25	,	,	PUNCT
fnp-6108	296	26	17	17	NUM
fnp-6108	296	27	alzheimer	alzheimer	X
fnp-6108	296	28	’s	’s	PART
fnp-6108	296	29	continuum	continuum	ADJ
fnp-6108	296	30	disease	disease	NOUN
fnp-6108	296	31	,	,	PUNCT
fnp-6108	296	32	11	11	NUM
fnp-6108	296	33	dementia	dementia	NOUN
fnp-6108	296	34	with	with	ADP
fnp-6108	296	35	lewy	lewy	PROPN
fnp-6108	296	36	bodies	body	NOUN
fnp-6108	296	37	,	,	PUNCT
fnp-6108	296	38	8	8	NUM
fnp-6108	296	39	normal	normal	ADJ
fnp-6108	296	40	pressure	pressure	NOUN
fnp-6108	296	41	hydrocephalus	hydrocephalus	NOUN
fnp-6108	296	42	,	,	PUNCT
fnp-6108	296	43	27	27	NUM
fnp-6108	296	44	other	other	ADJ
fnp-6108	296	45	or	or	CCONJ
fnp-6108	296	46	undetermined	undetermined	ADJ
fnp-6108	296	47	neurocognitive	neurocognitive	ADJ
fnp-6108	296	48	disease	disease	NOUN
fnp-6108	296	49	,	,	PUNCT
fnp-6108	296	50	and	and	CCONJ
fnp-6108	296	51	12	12	NUM
fnp-6108	296	52	controls	control	NOUN
fnp-6108	296	53	)	)	PUNCT
fnp-6108	296	54	were	be	AUX
fnp-6108	296	55	included	include	VERB
fnp-6108	296	56	.	.	PUNCT
fnp-6108	297	1	for	for	ADP
fnp-6108	297	2	tms	tms	PROPN
fnp-6108	297	3	,	,	PUNCT
fnp-6108	297	4	short	short	ADJ
fnp-6108	297	5	interval	interval	NOUN
fnp-6108	297	6	intracortical	intracortical	ADJ
fnp-6108	297	7	inhibition	inhibition	NOUN
fnp-6108	297	8	(	(	PUNCT
fnp-6108	297	9	sici	sici	NOUN
fnp-6108	297	10	)	)	PUNCT
fnp-6108	297	11	,	,	PUNCT
fnp-6108	297	12	intracortical	intracortical	ADJ
fnp-6108	297	13	facilitation	facilitation	NOUN
fnp-6108	297	14	(	(	PUNCT
fnp-6108	297	15	icf	icf	PROPN
fnp-6108	297	16	)	)	PUNCT
fnp-6108	297	17	,	,	PUNCT
fnp-6108	297	18	long	long	ADJ
fnp-6108	297	19	-	-	PUNCT
fnp-6108	297	20	interval	interval	NOUN
fnp-6108	297	21	cortical	cortical	ADJ
fnp-6108	297	22	inhibition	inhibition	NOUN
fnp-6108	297	23	(	(	PUNCT
fnp-6108	297	24	lici	lici	NOUN
fnp-6108	297	25	)	)	PUNCT
fnp-6108	297	26	and	and	CCONJ
fnp-6108	297	27	short	short	ADJ
fnp-6108	297	28	-	-	PUNCT
fnp-6108	297	29	latency	latency	NOUN
fnp-6108	297	30	afferent	afferent	NOUN
fnp-6108	297	31	inhibition	inhibition	NOUN
fnp-6108	297	32	(	(	PUNCT
fnp-6108	297	33	sai	sai	ADJ
fnp-6108	297	34	)	)	PUNCT
fnp-6108	297	35	were	be	AUX
fnp-6108	297	36	measured	measure	VERB
fnp-6108	297	37	.	.	PUNCT
fnp-6108	298	1	the	the	DET
fnp-6108	298	2	22	22	NUM
fnp-6108	298	3	items	item	NOUN
fnp-6108	298	4	in	in	ADP
fnp-6108	298	5	fbi	fbi	PROPN
fnp-6108	298	6	-	-	PUNCT
fnp-6108	298	7	mod	mod	PROPN
fnp-6108	298	8	were	be	AUX
fnp-6108	298	9	filled	fill	VERB
fnp-6108	298	10	by	by	ADP
fnp-6108	298	11	a	a	DET
fnp-6108	298	12	relative	relative	NOUN
fnp-6108	298	13	of	of	ADP
fnp-6108	298	14	the	the	DET
fnp-6108	298	15	patient	patient	NOUN
fnp-6108	298	16	.	.	PUNCT
fnp-6108	299	1	the	the	DET
fnp-6108	299	2	total	total	ADJ
fnp-6108	299	3	score	score	NOUN
fnp-6108	299	4	as	as	ADV
fnp-6108	299	5	well	well	ADV
fnp-6108	299	6	as	as	ADP
fnp-6108	299	7	the	the	DET
fnp-6108	299	8	presence	presence	NOUN
fnp-6108	299	9	and	and	CCONJ
fnp-6108	299	10	severity	severity	NOUN
fnp-6108	299	11	of	of	ADP
fnp-6108	299	12	each	each	DET
fnp-6108	299	13	symptom	symptom	NOUN
fnp-6108	299	14	were	be	AUX
fnp-6108	299	15	analysed	analyse	VERB
fnp-6108	299	16	separately	separately	ADV
fnp-6108	299	17	.	.	PUNCT
fnp-6108	300	1	results	result	NOUN
fnp-6108	300	2	:	:	PUNCT
fnp-6108	300	3	multiple	multiple	ADJ
fnp-6108	300	4	associations	association	NOUN
fnp-6108	300	5	were	be	AUX
fnp-6108	300	6	found	find	VERB
fnp-6108	300	7	in	in	ADP
fnp-6108	300	8	the	the	DET
fnp-6108	300	9	symptom	symptom	NOUN
fnp-6108	300	10	-	-	PUNCT
fnp-6108	300	11	wise	wise	ADJ
fnp-6108	300	12	analysis	analysis	NOUN
fnp-6108	300	13	.	.	PUNCT
fnp-6108	301	1	the	the	DET
fnp-6108	301	2	presence	presence	NOUN
fnp-6108	301	3	of	of	ADP
fnp-6108	301	4	restlessness	restlessness	NOUN
fnp-6108	301	5	was	be	AUX
fnp-6108	301	6	associated	associate	VERB
fnp-6108	301	7	with	with	ADP
fnp-6108	301	8	stronger	strong	ADJ
fnp-6108	301	9	inhibition	inhibition	NOUN
fnp-6108	301	10	in	in	ADP
fnp-6108	301	11	sai	sai	ADJ
fnp-6108	301	12	and	and	CCONJ
fnp-6108	301	13	sici	sici	NOUN
fnp-6108	301	14	tests	test	NOUN
fnp-6108	301	15	,	,	PUNCT
fnp-6108	301	16	while	while	SCONJ
fnp-6108	301	17	impaired	impaired	ADJ
fnp-6108	301	18	sici	sici	NOUN
fnp-6108	301	19	was	be	AUX
fnp-6108	301	20	associated	associate	VERB
fnp-6108	301	21	with	with	ADP
fnp-6108	301	22	the	the	DET
fnp-6108	301	23	presence	presence	NOUN
fnp-6108	301	24	of	of	ADP
fnp-6108	301	25	irritability	irritability	NOUN
fnp-6108	301	26	,	,	PUNCT
fnp-6108	301	27	and	and	CCONJ
fnp-6108	301	28	impaired	impaired	ADJ
fnp-6108	301	29	icf	icf	PROPN
fnp-6108	301	30	with	with	ADP
fnp-6108	301	31	the	the	DET
fnp-6108	301	32	severity	severity	NOUN
fnp-6108	301	33	of	of	ADP
fnp-6108	301	34	inattention	inattention	NOUN
fnp-6108	301	35	(	(	PUNCT
fnp-6108	301	36	p	p	X
fnp-6108	301	37	 	 	SPACE
fnp-6108	301	38	<	<	NOUN
fnp-6108	301	39	 	 	SPACE
fnp-6108	301	40	0.01	0.01	NUM
fnp-6108	301	41	for	for	ADP
fnp-6108	301	42	all	all	PRON
fnp-6108	301	43	)	)	PUNCT
fnp-6108	301	44	.	.	PUNCT
fnp-6108	302	1	the	the	DET
fnp-6108	302	2	fbi	fbi	PROPN
fnp-6108	302	3	-	-	PUNCT
fnp-6108	302	4	mod	mod	PROPN
fnp-6108	302	5	total	total	NOUN
fnp-6108	302	6	and	and	CCONJ
fnp-6108	302	7	positive	positive	ADJ
fnp-6108	302	8	scores	score	NOUN
fnp-6108	302	9	correlated	correlate	VERB
fnp-6108	302	10	with	with	ADP
fnp-6108	302	11	sai	sai	PROPN
fnp-6108	302	12	(	(	PUNCT
fnp-6108	302	13	rho	rho	NOUN
fnp-6108	302	14	 	 	SPACE
fnp-6108	302	15	=	=	NUM
fnp-6108	302	16	 	 	SPACE
fnp-6108	302	17	-0.2	-0.2	NOUN
fnp-6108	302	18	,	,	PUNCT
fnp-6108	302	19	p	p	X
fnp-6108	302	20	 	 	SPACE
fnp-6108	302	21	=	=	NOUN
fnp-6108	302	22	 	 	SPACE
fnp-6108	302	23	0.02	0.02	NUM
fnp-6108	302	24	for	for	ADP
fnp-6108	302	25	both	both	PRON
fnp-6108	302	26	)	)	PUNCT
fnp-6108	302	27	.	.	PUNCT
fnp-6108	303	1	conclusion	conclusion	NOUN
fnp-6108	303	2	:	:	PUNCT
fnp-6108	303	3	changes	change	NOUN
fnp-6108	303	4	observed	observe	VERB
fnp-6108	303	5	in	in	ADP
fnp-6108	303	6	the	the	DET
fnp-6108	303	7	gabaergic	gabaergic	ADJ
fnp-6108	303	8	(	(	PUNCT
fnp-6108	303	9	sici	sici	NOUN
fnp-6108	303	10	)	)	PUNCT
fnp-6108	303	11	,	,	PUNCT
fnp-6108	303	12	glutamatergic	glutamatergic	ADJ
fnp-6108	303	13	(	(	PUNCT
fnp-6108	303	14	icf	icf	PROPN
fnp-6108	303	15	)	)	PUNCT
fnp-6108	303	16	and	and	CCONJ
fnp-6108	303	17	acetylcholinergic	acetylcholinergic	NOUN
fnp-6108	303	18	(	(	PUNCT
fnp-6108	303	19	sai	sai	ADJ
fnp-6108	303	20	)	)	PUNCT
fnp-6108	303	21	systems	system	NOUN
fnp-6108	303	22	were	be	AUX
fnp-6108	303	23	found	find	VERB
fnp-6108	303	24	to	to	PART
fnp-6108	303	25	correlate	correlate	VERB
fnp-6108	303	26	with	with	ADP
fnp-6108	303	27	specific	specific	ADJ
fnp-6108	303	28	behavioral	behavioral	ADJ
fnp-6108	303	29	symptoms	symptom	NOUN
fnp-6108	303	30	,	,	PUNCT
fnp-6108	303	31	independently	independently	ADV
fnp-6108	303	32	from	from	ADP
fnp-6108	303	33	the	the	DET
fnp-6108	303	34	underlying	underlie	VERB
fnp-6108	303	35	diagnostic	diagnostic	ADJ
fnp-6108	303	36	entity	entity	NOUN
fnp-6108	303	37	.	.	PUNCT
fnp-6108	304	1	these	these	DET
fnp-6108	304	2	results	result	NOUN
fnp-6108	304	3	and	and	CCONJ
fnp-6108	304	4	increasing	increase	VERB
fnp-6108	304	5	dataset	dataset	NOUN
fnp-6108	304	6	will	will	AUX
fnp-6108	304	7	enable	enable	VERB
fnp-6108	304	8	more	more	ADV
fnp-6108	304	9	comprehensive	comprehensive	ADJ
fnp-6108	304	10	understanding	understanding	NOUN
fnp-6108	304	11	of	of	ADP
fnp-6108	304	12	pathophysiology	pathophysiology	NOUN
fnp-6108	304	13	behind	behind	ADP
fnp-6108	304	14	distinct	distinct	ADJ
fnp-6108	304	15	behavioral	behavioral	ADJ
fnp-6108	304	16	symptoms	symptom	NOUN
fnp-6108	304	17	.	.	PUNCT
fnp-6108	304	18	  	  	SPACE
fnp-6108	305	1	free	free	ADJ
fnp-6108	305	2	neuropathol	neuropathol	NOUN
fnp-6108	305	3	5:30:32	5:30:32	PRON
fnp-6108	305	4	digital	digital	ADJ
fnp-6108	305	5	morphological	morphological	ADJ
fnp-6108	305	6	profiling	profiling	NOUN
fnp-6108	305	7	reveals	reveal	NOUN
fnp-6108	305	8	regionaland	regionaland	NOUN
fnp-6108	305	9	disease	disease	NOUN
fnp-6108	305	10	-	-	PUNCT
fnp-6108	305	11	specific	specific	ADJ
fnp-6108	305	12	differences	difference	NOUN
fnp-6108	305	13	of	of	ADP
fnp-6108	305	14	glial	glial	ADJ
fnp-6108	305	15	cells	cell	NOUN
fnp-6108	305	16	in	in	ADP
fnp-6108	305	17	neurodegenerative	neurodegenerative	ADJ
fnp-6108	305	18	proteinopathies	proteinopathie	NOUN
fnp-6108	305	19	vladyslav	vladyslav	NOUN
fnp-6108	305	20	vadymovych	vadymovych	NOUN
fnp-6108	305	21	tkach1	tkach1	PROPN
fnp-6108	305	22	,	,	PUNCT
fnp-6108	305	23	ausrine	ausrine	NOUN
fnp-6108	305	24	areskeviciute1	areskeviciute1	PROPN
fnp-6108	305	25	,	,	PUNCT
fnp-6108	305	26	remarh	remarh	ADJ
fnp-6108	305	27	bsoul1	bsoul1	PROPN
fnp-6108	305	28	,	,	PUNCT
fnp-6108	305	29	eva	eva	PROPN
fnp-6108	305	30	løbner	løbner	PROPN
fnp-6108	305	31	lund1	lund1	PROPN
fnp-6108	305	32	danish	danish	ADJ
fnp-6108	305	33	reference	reference	NOUN
fnp-6108	305	34	center	center	NOUN
fnp-6108	305	35	for	for	ADP
fnp-6108	305	36	prion	prion	NOUN
fnp-6108	305	37	diseases	disease	NOUN
fnp-6108	305	38	,	,	PUNCT
fnp-6108	305	39	department	department	NOUN
fnp-6108	305	40	of	of	ADP
fnp-6108	305	41	pathology	pathology	PROPN
fnp-6108	305	42	,	,	PUNCT
fnp-6108	305	43	copenhagen	copenhagen	PROPN
fnp-6108	305	44	university	university	PROPN
fnp-6108	305	45	hospital	hospital	NOUN
fnp-6108	305	46	,	,	PUNCT
fnp-6108	305	47	copenhagen	copenhagen	PROPN
fnp-6108	305	48	,	,	PUNCT
fnp-6108	305	49	denmark	denmark	NOUN
fnp-6108	305	50	objectives	objective	NOUN
fnp-6108	305	51	:	:	PUNCT
fnp-6108	305	52	the	the	DET
fnp-6108	305	53	importance	importance	NOUN
fnp-6108	305	54	of	of	ADP
fnp-6108	305	55	glial	glial	ADJ
fnp-6108	305	56	cells	cell	NOUN
fnp-6108	305	57	and	and	CCONJ
fnp-6108	305	58	neuroinflammation	neuroinflammation	NOUN
fnp-6108	305	59	has	have	AUX
fnp-6108	305	60	been	be	AUX
fnp-6108	305	61	established	establish	VERB
fnp-6108	305	62	in	in	ADP
fnp-6108	305	63	neurodegenerative	neurodegenerative	ADJ
fnp-6108	305	64	proteinopathies	proteinopathie	NOUN
fnp-6108	305	65	.	.	PUNCT
fnp-6108	306	1	this	this	DET
fnp-6108	306	2	study	study	NOUN
fnp-6108	306	3	aims	aim	VERB
fnp-6108	306	4	to	to	PART
fnp-6108	306	5	characterize	characterize	VERB
fnp-6108	306	6	regional	regional	ADJ
fnp-6108	306	7	differences	difference	NOUN
fnp-6108	306	8	in	in	ADP
fnp-6108	306	9	microglial	microglial	ADJ
fnp-6108	306	10	and	and	CCONJ
fnp-6108	306	11	astrocytic	astrocytic	ADJ
fnp-6108	306	12	reactivity	reactivity	NOUN
fnp-6108	306	13	in	in	ADP
fnp-6108	306	14	two	two	NUM
fnp-6108	306	15	different	different	ADJ
fnp-6108	306	16	neurodegenerative	neurodegenerative	ADJ
fnp-6108	306	17	proteinopathies	proteinopathie	NOUN
fnp-6108	306	18	alzheimer	alzheimer	PROPN
fnp-6108	306	19	’s	’s	PART
fnp-6108	306	20	disease	disease	NOUN
fnp-6108	306	21	(	(	PUNCT
fnp-6108	306	22	ad	ad	NOUN
fnp-6108	306	23	)	)	PUNCT
fnp-6108	306	24	and	and	CCONJ
fnp-6108	306	25	creutzfeldt	creutzfeldt	ADJ
fnp-6108	306	26	-	-	PUNCT
fnp-6108	306	27	jakob	jakob	PROPN
fnp-6108	306	28	’s	’s	PART
fnp-6108	306	29	disease	disease	NOUN
fnp-6108	306	30	(	(	PUNCT
fnp-6108	306	31	cjd	cjd	PROPN
fnp-6108	306	32	)	)	PUNCT
fnp-6108	306	33	.	.	PUNCT
fnp-6108	307	1	materials	material	NOUN
fnp-6108	307	2	and	and	CCONJ
fnp-6108	307	3	methods	method	NOUN
fnp-6108	307	4	:	:	PUNCT
fnp-6108	307	5	post	post	ADJ
fnp-6108	307	6	-	-	ADJ
fnp-6108	307	7	mortem	mortem	ADJ
fnp-6108	307	8	brain	brain	NOUN
fnp-6108	307	9	tissue	tissue	NOUN
fnp-6108	307	10	from	from	ADP
fnp-6108	307	11	both	both	CCONJ
fnp-6108	307	12	frontal	frontal	ADJ
fnp-6108	307	13	and	and	CCONJ
fnp-6108	307	14	occipital	occipital	ADJ
fnp-6108	307	15	neocortex	neocortex	NOUN
fnp-6108	307	16	was	be	AUX
fnp-6108	307	17	collected	collect	VERB
fnp-6108	307	18	from	from	ADP
fnp-6108	307	19	patients	patient	NOUN
fnp-6108	307	20	diagnosed	diagnose	VERB
fnp-6108	307	21	with	with	ADP
fnp-6108	307	22	either	either	DET
fnp-6108	307	23	ad	ad	NOUN
fnp-6108	307	24	,	,	PUNCT
fnp-6108	307	25	cjd	cjd	NOUN
fnp-6108	307	26	or	or	CCONJ
fnp-6108	307	27	with	with	ADP
fnp-6108	307	28	no	no	DET
fnp-6108	307	29	neuropathological	neuropathological	ADJ
fnp-6108	307	30	findings	finding	NOUN
fnp-6108	307	31	.	.	PUNCT
fnp-6108	308	1	the	the	DET
fnp-6108	308	2	brain	brain	NOUN
fnp-6108	308	3	tissue	tissue	NOUN
fnp-6108	308	4	was	be	AUX
fnp-6108	308	5	spatially	spatially	ADV
fnp-6108	308	6	divided	divide	VERB
fnp-6108	308	7	into	into	ADP
fnp-6108	308	8	white	white	ADJ
fnp-6108	308	9	matter	matter	NOUN
fnp-6108	308	10	,	,	PUNCT
fnp-6108	308	11	lower	low	ADJ
fnp-6108	308	12	grey	grey	NOUN
fnp-6108	308	13	matter	matter	NOUN
fnp-6108	308	14	,	,	PUNCT
fnp-6108	308	15	and	and	CCONJ
fnp-6108	308	16	an	an	DET
fnp-6108	308	17	upper	upper	ADJ
fnp-6108	308	18	grey	grey	NOUN
fnp-6108	308	19	matter	matter	NOUN
fnp-6108	308	20	area	area	NOUN
fnp-6108	308	21	.	.	PUNCT
fnp-6108	309	1	a	a	DET
fnp-6108	309	2	custom	custom	NOUN
fnp-6108	309	3	digital	digital	ADJ
fnp-6108	309	4	morphological	morphological	ADJ
fnp-6108	309	5	profiling	profiling	NOUN
fnp-6108	309	6	pipeline	pipeline	NOUN
fnp-6108	309	7	was	be	AUX
fnp-6108	309	8	applied	apply	VERB
fnp-6108	309	9	on	on	ADP
fnp-6108	309	10	immunofluorescence	immunofluorescence	NOUN
fnp-6108	309	11	images	image	NOUN
fnp-6108	309	12	of	of	ADP
fnp-6108	309	13	the	the	DET
fnp-6108	309	14	tissue	tissue	NOUN
fnp-6108	309	15	slides	slide	NOUN
fnp-6108	309	16	,	,	PUNCT
fnp-6108	309	17	which	which	PRON
fnp-6108	309	18	were	be	AUX
fnp-6108	309	19	stained	stain	VERB
fnp-6108	309	20	for	for	ADP
fnp-6108	309	21	both	both	PRON
fnp-6108	309	22	iba1	iba1	PROPN
fnp-6108	309	23	(	(	PUNCT
fnp-6108	309	24	microglia	microglia	NOUN
fnp-6108	309	25	)	)	PUNCT
fnp-6108	309	26	and	and	CCONJ
fnp-6108	309	27	gfap	gfap	ADJ
fnp-6108	309	28	(	(	PUNCT
fnp-6108	309	29	astrocytes	astrocyte	NOUN
fnp-6108	309	30	)	)	PUNCT
fnp-6108	309	31	.	.	PUNCT
fnp-6108	310	1	subsequent	subsequent	ADJ
fnp-6108	310	2	unsupervised	unsupervised	ADJ
fnp-6108	310	3	clustering	clustering	NOUN
fnp-6108	310	4	classified	classify	VERB
fnp-6108	310	5	the	the	DET
fnp-6108	310	6	segmented	segment	VERB
fnp-6108	310	7	cells	cell	NOUN
fnp-6108	310	8	based	base	VERB
fnp-6108	310	9	on	on	ADP
fnp-6108	310	10	measured	measure	VERB
fnp-6108	310	11	morphological	morphological	ADJ
fnp-6108	310	12	features	feature	NOUN
fnp-6108	310	13	.	.	PUNCT
fnp-6108	311	1	protein	protein	NOUN
fnp-6108	311	2	expression	expression	NOUN
fnp-6108	311	3	data	datum	NOUN
fnp-6108	311	4	was	be	AUX
fnp-6108	311	5	obtained	obtain	VERB
fnp-6108	311	6	using	use	VERB
fnp-6108	311	7	nanostring	nanostre	VERB
fnp-6108	311	8	protein	protein	NOUN
fnp-6108	311	9	assays	assay	NOUN
fnp-6108	311	10	and	and	CCONJ
fnp-6108	311	11	geomx	geomx	VERB
fnp-6108	311	12	spatial	spatial	ADJ
fnp-6108	311	13	profiling	profiling	NOUN
fnp-6108	311	14	.	.	PUNCT
fnp-6108	312	1	results	result	NOUN
fnp-6108	312	2	and	and	CCONJ
fnp-6108	312	3	conclusion	conclusion	NOUN
fnp-6108	312	4	:	:	PUNCT
fnp-6108	312	5	predominant	predominant	ADJ
fnp-6108	312	6	clusters	cluster	NOUN
fnp-6108	312	7	representing	represent	VERB
fnp-6108	312	8	reactive	reactive	ADJ
fnp-6108	312	9	states	state	NOUN
fnp-6108	312	10	(	(	PUNCT
fnp-6108	312	11	ameboid	ameboid	NOUN
fnp-6108	312	12	microglia	microglia	ADJ
fnp-6108	312	13	and	and	CCONJ
fnp-6108	312	14	ramified	ramified	ADJ
fnp-6108	312	15	astrocytes	astrocyte	NOUN
fnp-6108	312	16	)	)	PUNCT
fnp-6108	312	17	were	be	AUX
fnp-6108	312	18	identified	identify	VERB
fnp-6108	312	19	for	for	ADP
fnp-6108	312	20	both	both	DET
fnp-6108	312	21	cell	cell	NOUN
fnp-6108	312	22	types	type	NOUN
fnp-6108	312	23	respectively	respectively	ADV
fnp-6108	312	24	.	.	PUNCT
fnp-6108	313	1	the	the	DET
fnp-6108	313	2	disease	disease	NOUN
fnp-6108	313	3	groups	group	NOUN
fnp-6108	313	4	,	,	PUNCT
fnp-6108	313	5	and	and	CCONJ
fnp-6108	313	6	especially	especially	ADV
fnp-6108	313	7	cjd	cjd	NOUN
fnp-6108	313	8	patients	patient	NOUN
fnp-6108	313	9	,	,	PUNCT
fnp-6108	313	10	had	have	AUX
fnp-6108	313	11	increased	increase	VERB
fnp-6108	313	12	presence	presence	NOUN
fnp-6108	313	13	of	of	ADP
fnp-6108	313	14	reactive	reactive	ADJ
fnp-6108	313	15	microglia	microglia	NOUN
fnp-6108	313	16	compared	compare	VERB
fnp-6108	313	17	to	to	ADP
fnp-6108	313	18	controls	control	NOUN
fnp-6108	313	19	,	,	PUNCT
fnp-6108	313	20	which	which	PRON
fnp-6108	313	21	was	be	AUX
fnp-6108	313	22	a	a	DET
fnp-6108	313	23	specific	specific	ADJ
fnp-6108	313	24	finding	finding	NOUN
fnp-6108	313	25	found	find	VERB
fnp-6108	313	26	in	in	ADP
fnp-6108	313	27	grey	grey	PROPN
fnp-6108	313	28	matter	matter	NOUN
fnp-6108	313	29	but	but	CCONJ
fnp-6108	313	30	not	not	PART
fnp-6108	313	31	in	in	ADP
fnp-6108	313	32	white	white	ADJ
fnp-6108	313	33	matter	matter	NOUN
fnp-6108	313	34	.	.	PUNCT
fnp-6108	314	1	increased	increase	VERB
fnp-6108	314	2	presence	presence	NOUN
fnp-6108	314	3	of	of	ADP
fnp-6108	314	4	reactive	reactive	ADJ
fnp-6108	314	5	astrocytes	astrocyte	NOUN
fnp-6108	314	6	was	be	AUX
fnp-6108	314	7	apparent	apparent	ADJ
fnp-6108	314	8	for	for	ADP
fnp-6108	314	9	both	both	DET
fnp-6108	314	10	diseases	disease	NOUN
fnp-6108	314	11	and	and	CCONJ
fnp-6108	314	12	across	across	ADP
fnp-6108	314	13	all	all	DET
fnp-6108	314	14	cortex	cortex	NOUN
fnp-6108	314	15	layers	layer	NOUN
fnp-6108	314	16	,	,	PUNCT
fnp-6108	314	17	including	include	VERB
fnp-6108	314	18	white	white	ADJ
fnp-6108	314	19	matter	matter	NOUN
fnp-6108	314	20	.	.	PUNCT
fnp-6108	315	1	integration	integration	NOUN
fnp-6108	315	2	of	of	ADP
fnp-6108	315	3	the	the	DET
fnp-6108	315	4	morphological	morphological	ADJ
fnp-6108	315	5	data	datum	NOUN
fnp-6108	315	6	with	with	ADP
fnp-6108	315	7	protein	protein	NOUN
fnp-6108	315	8	expression	expression	NOUN
fnp-6108	315	9	data	datum	NOUN
fnp-6108	315	10	obtained	obtain	VERB
fnp-6108	315	11	from	from	ADP
fnp-6108	315	12	the	the	DET
fnp-6108	315	13	same	same	ADJ
fnp-6108	315	14	tissue	tissue	NOUN
fnp-6108	315	15	slides	slide	NOUN
fnp-6108	315	16	showed	show	VERB
fnp-6108	315	17	correlation	correlation	NOUN
fnp-6108	315	18	between	between	ADP
fnp-6108	315	19	cell	cell	NOUN
fnp-6108	315	20	morphology	morphology	NOUN
fnp-6108	315	21	and	and	CCONJ
fnp-6108	315	22	expression	expression	NOUN
fnp-6108	315	23	level	level	NOUN
fnp-6108	315	24	of	of	ADP
fnp-6108	315	25	different	different	ADJ
fnp-6108	315	26	proteins	protein	NOUN
fnp-6108	315	27	.	.	PUNCT
fnp-6108	316	1	these	these	DET
fnp-6108	316	2	results	result	NOUN
fnp-6108	316	3	illustrate	illustrate	VERB
fnp-6108	316	4	that	that	PRON
fnp-6108	316	5	morphological	morphological	ADJ
fnp-6108	316	6	profiling	profiling	NOUN
fnp-6108	316	7	can	can	AUX
fnp-6108	316	8	be	be	AUX
fnp-6108	316	9	applied	apply	VERB
fnp-6108	316	10	in	in	ADP
fnp-6108	316	11	a	a	DET
fnp-6108	316	12	digital	digital	ADJ
fnp-6108	316	13	pathology	pathology	NOUN
fnp-6108	316	14	setting	set	VERB
fnp-6108	316	15	to	to	PART
fnp-6108	316	16	study	study	VERB
fnp-6108	316	17	disease	disease	NOUN
fnp-6108	316	18	specific	specific	ADJ
fnp-6108	316	19	alterations	alteration	NOUN
fnp-6108	316	20	of	of	ADP
fnp-6108	316	21	cell	cell	NOUN
fnp-6108	316	22	morphology	morphology	NOUN
fnp-6108	316	23	.	.	PUNCT
fnp-6108	316	24	  	  	SPACE
fnp-6108	317	1	free	free	ADJ
fnp-6108	317	2	neuropathol	neuropathol	NOUN
fnp-6108	317	3	5:30:33	5:30:33	NUM
fnp-6108	317	4	an	an	DET
fnp-6108	317	5	update	update	NOUN
fnp-6108	317	6	on	on	ADP
fnp-6108	317	7	alzheimer	alzheimer	PROPN
fnp-6108	317	8	’s	’s	PART
fnp-6108	317	9	disease	disease	NOUN
fnp-6108	317	10	tau	tau	PROPN
fnp-6108	317	11	subtypes	subtype	NOUN
fnp-6108	317	12	:	:	PUNCT
fnp-6108	317	13	clinical	clinical	ADJ
fnp-6108	317	14	and	and	CCONJ
fnp-6108	317	15	biological	biological	ADJ
fnp-6108	317	16	insights	insight	NOUN
fnp-6108	317	17	jacob	jacob	PROPN
fnp-6108	317	18	vogel1	vogel1	PROPN
fnp-6108	317	19	,	,	PUNCT
fnp-6108	317	20	lyduine	lyduine	PROPN
fnp-6108	317	21	collij2,3	collij2,3	PROPN
fnp-6108	317	22	,	,	PUNCT
fnp-6108	317	23	sophie	sophie	PROPN
fnp-6108	317	24	mastenbroek2,3	mastenbroek2,3	PROPN
fnp-6108	317	25	,	,	PUNCT
fnp-6108	317	26	alexa	alexa	PROPN
fnp-6108	317	27	pichet	pichet	PROPN
fnp-6108	317	28	binette3	binette3	PROPN
fnp-6108	317	29	,	,	PUNCT
fnp-6108	317	30	ruben	ruben	PROPN
fnp-6108	317	31	smith3,4	smith3,4	PROPN
fnp-6108	317	32	,	,	PUNCT
fnp-6108	317	33	sebastian	sebastian	PROPN
fnp-6108	317	34	palmqvist3,4	palmqvist3,4	PROPN
fnp-6108	317	35	,	,	PUNCT
fnp-6108	317	36	niklas	niklas	PROPN
fnp-6108	317	37	mattsson	mattsson	PROPN
fnp-6108	317	38	-	-	PUNCT
fnp-6108	317	39	carlgren3,4	carlgren3,4	PROPN
fnp-6108	317	40	,	,	PUNCT
fnp-6108	317	41	olof	olof	NOUN
fnp-6108	317	42	strandberg3,4	strandberg3,4	PROPN
fnp-6108	317	43	,	,	PUNCT
fnp-6108	317	44	rik	rik	PROPN
fnp-6108	317	45	ossenkoppele3,5	ossenkoppele3,5	PROPN
fnp-6108	317	46	,	,	PUNCT
fnp-6108	317	47	oskar	oskar	PROPN
fnp-6108	317	48	hansson3,4	hansson3,4	PROPN
fnp-6108	317	49	department	department	PROPN
fnp-6108	317	50	of	of	ADP
fnp-6108	317	51	clinical	clinical	ADJ
fnp-6108	317	52	science	science	PROPN
fnp-6108	317	53	malmö	malmö	PROPN
fnp-6108	317	54	,	,	PUNCT
fnp-6108	317	55	scilifelab	scilifelab	PROPN
fnp-6108	317	56	,	,	PUNCT
fnp-6108	317	57	lund	lund	PROPN
fnp-6108	317	58	university	university	PROPN
fnp-6108	317	59	,	,	PUNCT
fnp-6108	317	60	lund	lund	PROPN
fnp-6108	317	61	,	,	PUNCT
fnp-6108	317	62	sweden	sweden	PROPN
fnp-6108	317	63	amsterdam	amsterdam	PROPN
fnp-6108	317	64	umc	umc	PROPN
fnp-6108	317	65	,	,	PUNCT
fnp-6108	317	66	department	department	NOUN
fnp-6108	317	67	of	of	ADP
fnp-6108	317	68	radiology	radiology	NOUN
fnp-6108	317	69	and	and	CCONJ
fnp-6108	317	70	nuclear	nuclear	ADJ
fnp-6108	317	71	medicine	medicine	NOUN
fnp-6108	317	72	,	,	PUNCT
fnp-6108	317	73	amsterdam	amsterdam	PROPN
fnp-6108	317	74	,	,	PUNCT
fnp-6108	317	75	the	the	DET
fnp-6108	317	76	netherlands	netherlands	PROPN
fnp-6108	317	77	clinical	clinical	ADJ
fnp-6108	317	78	memory	memory	NOUN
fnp-6108	317	79	research	research	NOUN
fnp-6108	317	80	unit	unit	NOUN
fnp-6108	317	81	,	,	PUNCT
fnp-6108	317	82	department	department	NOUN
fnp-6108	317	83	of	of	ADP
fnp-6108	317	84	clinical	clinical	ADJ
fnp-6108	317	85	sciences	sciences	PROPN
fnp-6108	317	86	malmö	malmö	PROPN
fnp-6108	317	87	,	,	PUNCT
fnp-6108	317	88	lund	lund	PROPN
fnp-6108	317	89	university	university	PROPN
fnp-6108	317	90	,	,	PUNCT
fnp-6108	317	91	lund	lund	PROPN
fnp-6108	317	92	,	,	PUNCT
fnp-6108	317	93	sweden	sweden	PROPN
fnp-6108	317	94	memory	memory	PROPN
fnp-6108	317	95	clinic	clinic	PROPN
fnp-6108	317	96	,	,	PUNCT
fnp-6108	317	97	skåne	skåne	PROPN
fnp-6108	317	98	university	university	PROPN
fnp-6108	317	99	hospital	hospital	NOUN
fnp-6108	317	100	,	,	PUNCT
fnp-6108	317	101	malmö	malmö	PROPN
fnp-6108	317	102	,	,	PUNCT
fnp-6108	317	103	sweden	sweden	PROPN
fnp-6108	317	104	amsterdam	amsterdam	PROPN
fnp-6108	317	105	umc	umc	PROPN
fnp-6108	317	106	,	,	PUNCT
fnp-6108	317	107	alzheimer	alzheimer	PROPN
fnp-6108	317	108	center	center	PROPN
fnp-6108	317	109	amsterdam	amsterdam	PROPN
fnp-6108	317	110	,	,	PUNCT
fnp-6108	317	111	department	department	NOUN
fnp-6108	317	112	of	of	ADP
fnp-6108	317	113	neurology	neurology	NOUN
fnp-6108	317	114	,	,	PUNCT
fnp-6108	317	115	amsterdam	amsterdam	PROPN
fnp-6108	317	116	,	,	PUNCT
fnp-6108	317	117	the	the	DET
fnp-6108	317	118	netherlands	netherlands	PROPN
fnp-6108	317	119	objectives	objective	VERB
fnp-6108	317	120	:	:	PUNCT
fnp-6108	317	121	using	use	VERB
fnp-6108	317	122	positron	positron	NOUN
fnp-6108	317	123	emission	emission	NOUN
fnp-6108	317	124	tomography	tomography	NOUN
fnp-6108	317	125	(	(	PUNCT
fnp-6108	317	126	pet	pet	NOUN
fnp-6108	317	127	)	)	PUNCT
fnp-6108	317	128	,	,	PUNCT
fnp-6108	317	129	we	we	PRON
fnp-6108	317	130	recently	recently	ADV
fnp-6108	317	131	characterized	characterize	VERB
fnp-6108	317	132	four	four	NUM
fnp-6108	317	133	subtypes	subtype	NOUN
fnp-6108	317	134	of	of	ADP
fnp-6108	317	135	tau	tau	PROPN
fnp-6108	317	136	accumulation	accumulation	NOUN
fnp-6108	317	137	within	within	ADP
fnp-6108	317	138	the	the	DET
fnp-6108	317	139	ad	ad	NOUN
fnp-6108	317	140	population	population	NOUN
fnp-6108	317	141	,	,	PUNCT
fnp-6108	317	142	each	each	PRON
fnp-6108	317	143	with	with	ADP
fnp-6108	317	144	distinct	distinct	ADJ
fnp-6108	317	145	clinicopathological	clinicopathological	ADJ
fnp-6108	317	146	profiles	profile	NOUN
fnp-6108	317	147	.	.	PUNCT
fnp-6108	318	1	validation	validation	NOUN
fnp-6108	318	2	and	and	CCONJ
fnp-6108	318	3	further	further	ADJ
fnp-6108	318	4	characterization	characterization	NOUN
fnp-6108	318	5	of	of	ADP
fnp-6108	318	6	these	these	DET
fnp-6108	318	7	subtypes	subtype	NOUN
fnp-6108	318	8	is	be	AUX
fnp-6108	318	9	critical	critical	ADJ
fnp-6108	318	10	to	to	PART
fnp-6108	318	11	better	well	ADV
fnp-6108	318	12	understand	understand	VERB
fnp-6108	318	13	their	their	PRON
fnp-6108	318	14	clinical	clinical	ADJ
fnp-6108	318	15	and	and	CCONJ
fnp-6108	318	16	therapeutic	therapeutic	ADJ
fnp-6108	318	17	relevance	relevance	NOUN
fnp-6108	318	18	.	.	PUNCT
fnp-6108	319	1	materials	material	NOUN
fnp-6108	319	2	and	and	CCONJ
fnp-6108	319	3	methods	method	NOUN
fnp-6108	319	4	:	:	PUNCT
fnp-6108	319	5	we	we	PRON
fnp-6108	319	6	applied	apply	VERB
fnp-6108	319	7	the	the	DET
fnp-6108	319	8	previously	previously	ADV
fnp-6108	319	9	established	establish	VERB
fnp-6108	319	10	subtype	subtype	NOUN
fnp-6108	319	11	and	and	CCONJ
fnp-6108	319	12	stage	stage	NOUN
fnp-6108	319	13	inference	inference	NOUN
fnp-6108	319	14	(	(	PUNCT
fnp-6108	319	15	sustain	sustain	VERB
fnp-6108	319	16	)	)	PUNCT
fnp-6108	319	17	model	model	NOUN
fnp-6108	319	18	to	to	ADP
fnp-6108	319	19	1252	1252	NUM
fnp-6108	319	20	biofinder-2	biofinder-2	ADP
fnp-6108	319	21	(	(	PUNCT
fnp-6108	319	22	bf2	bf2	NOUN
fnp-6108	319	23	)	)	PUNCT
fnp-6108	319	24	participants	participant	NOUN
fnp-6108	319	25	with	with	ADP
fnp-6108	319	26	available	available	ADJ
fnp-6108	319	27	[	[	PUNCT
fnp-6108	319	28	18f]ro948	18f]ro948	PROPN
fnp-6108	319	29	tau	tau	PROPN
fnp-6108	319	30	-	-	PUNCT
fnp-6108	319	31	pet	pet	NOUN
fnp-6108	319	32	.	.	PUNCT
fnp-6108	320	1	linear	linear	PROPN
fnp-6108	320	2	and	and	CCONJ
fnp-6108	320	3	mixed	mixed	ADJ
fnp-6108	320	4	-	-	PUNCT
fnp-6108	320	5	effects	effect	NOUN
fnp-6108	320	6	models	model	NOUN
fnp-6108	320	7	assessed	assess	VERB
fnp-6108	320	8	subtype	subtype	NOUN
fnp-6108	320	9	differences	difference	NOUN
fnp-6108	320	10	in	in	ADP
fnp-6108	320	11	csf	csf	ADJ
fnp-6108	320	12	-	-	PUNCT
fnp-6108	320	13	biomarkers	biomarker	NOUN
fnp-6108	320	14	regional	regional	ADJ
fnp-6108	320	15	,	,	PUNCT
fnp-6108	320	16	and	and	CCONJ
fnp-6108	320	17	brain	brain	NOUN
fnp-6108	320	18	atrophy	atrophy	NOUN
fnp-6108	320	19	and	and	CCONJ
fnp-6108	320	20	cognition	cognition	NOUN
fnp-6108	320	21	over	over	ADP
fnp-6108	320	22	time	time	NOUN
fnp-6108	320	23	,	,	PUNCT
fnp-6108	320	24	respectively	respectively	ADV
fnp-6108	320	25	.	.	PUNCT
fnp-6108	321	1	models	model	NOUN
fnp-6108	321	2	included	include	VERB
fnp-6108	321	3	age	age	NOUN
fnp-6108	321	4	,	,	PUNCT
fnp-6108	321	5	sex	sex	NOUN
fnp-6108	321	6	,	,	PUNCT
fnp-6108	321	7	and	and	CCONJ
fnp-6108	321	8	nuisance	nuisance	ADJ
fnp-6108	321	9	covariates	covariate	NOUN
fnp-6108	321	10	and	and	CCONJ
fnp-6108	321	11	were	be	AUX
fnp-6108	321	12	fdr	fdr	PROPN
fnp-6108	321	13	-	-	PUNCT
fnp-6108	321	14	corrected	correct	VERB
fnp-6108	321	15	.	.	PUNCT
fnp-6108	322	1	exploratory	exploratory	ADJ
fnp-6108	322	2	analysis	analysis	NOUN
fnp-6108	322	3	tested	test	VERB
fnp-6108	322	4	subtype	subtype	NOUN
fnp-6108	322	5	differences	difference	NOUN
fnp-6108	322	6	in	in	ADP
fnp-6108	322	7	global	global	ADJ
fnp-6108	322	8	and	and	CCONJ
fnp-6108	322	9	local	local	ADJ
fnp-6108	322	10	functional	functional	ADJ
fnp-6108	322	11	mri	mri	NOUN
fnp-6108	322	12	(	(	PUNCT
fnp-6108	322	13	fmri	fmri	ADJ
fnp-6108	322	14	)	)	PUNCT
fnp-6108	322	15	connectivity	connectivity	NOUN
fnp-6108	322	16	,	,	PUNCT
fnp-6108	322	17	as	as	ADV
fnp-6108	322	18	well	well	ADV
fnp-6108	322	19	as	as	ADP
fnp-6108	322	20	in	in	ADP
fnp-6108	322	21	prevalence	prevalence	NOUN
fnp-6108	322	22	of	of	ADP
fnp-6108	322	23	top	top	ADJ
fnp-6108	322	24	ad	ad	NOUN
fnp-6108	322	25	risk	risk	NOUN
fnp-6108	322	26	genes	gene	NOUN
fnp-6108	322	27	results	result	VERB
fnp-6108	322	28	:	:	PUNCT
fnp-6108	322	29	participants	participant	NOUN
fnp-6108	322	30	classified	classify	VERB
fnp-6108	322	31	to	to	ADP
fnp-6108	322	32	the	the	DET
fnp-6108	322	33	limbic	limbic	NOUN
fnp-6108	322	34	-	-	PUNCT
fnp-6108	322	35	subtype	subtype	NOUN
fnp-6108	322	36	were	be	AUX
fnp-6108	322	37	older	old	ADJ
fnp-6108	322	38	,	,	PUNCT
fnp-6108	322	39	while	while	SCONJ
fnp-6108	322	40	posterior	posterior	ADJ
fnp-6108	322	41	-	-	PUNCT
fnp-6108	322	42	subtype	subtype	NOUN
fnp-6108	322	43	participants	participant	NOUN
fnp-6108	322	44	were	be	AUX
fnp-6108	322	45	less	less	ADV
fnp-6108	322	46	often	often	ADV
fnp-6108	322	47	apoe	apoe	ADJ
fnp-6108	322	48	-	-	PUNCT
fnp-6108	322	49	ε4	ε4	NOUN
fnp-6108	322	50	carriers	carrier	NOUN
fnp-6108	322	51	.	.	PUNCT
fnp-6108	323	1	longitudinal	longitudinal	ADJ
fnp-6108	323	2	regional	regional	ADJ
fnp-6108	323	3	gray	gray	ADJ
fnp-6108	323	4	matter	matter	NOUN
fnp-6108	323	5	volume	volume	NOUN
fnp-6108	323	6	reduction	reduction	NOUN
fnp-6108	323	7	matched	match	VERB
fnp-6108	323	8	subtype	subtype	NOUN
fnp-6108	323	9	-	-	PUNCT
fnp-6108	323	10	specific	specific	ADJ
fnp-6108	323	11	tau	tau	NOUN
fnp-6108	323	12	patterns	pattern	NOUN
fnp-6108	323	13	.	.	PUNCT
fnp-6108	324	1	posterior	posterior	ADJ
fnp-6108	324	2	and	and	CCONJ
fnp-6108	324	3	lateral	lateral	ADJ
fnp-6108	324	4	-	-	PUNCT
fnp-6108	324	5	temporal	temporal	ADJ
fnp-6108	324	6	-	-	PUNCT
fnp-6108	324	7	subtype	subtype	NOUN
fnp-6108	324	8	participants	participant	NOUN
fnp-6108	324	9	had	have	VERB
fnp-6108	324	10	higher	high	ADJ
fnp-6108	324	11	levels	level	NOUN
fnp-6108	324	12	of	of	ADP
fnp-6108	324	13	nfl	nfl	PROPN
fnp-6108	324	14	,	,	PUNCT
fnp-6108	324	15	ykl40	ykl40	PROPN
fnp-6108	324	16	,	,	PUNCT
fnp-6108	324	17	and	and	CCONJ
fnp-6108	324	18	ngn	ngn	PROPN
fnp-6108	324	19	compared	compare	VERB
fnp-6108	324	20	to	to	ADP
fnp-6108	324	21	limbic	limbic	ADJ
fnp-6108	324	22	-	-	PUNCT
fnp-6108	324	23	subtype	subtype	NOUN
fnp-6108	324	24	participants	participant	NOUN
fnp-6108	324	25	.	.	PUNCT
fnp-6108	325	1	limbic	limbic	NOUN
fnp-6108	325	2	-	-	PUNCT
fnp-6108	325	3	subtype	subtype	NOUN
fnp-6108	325	4	and	and	CCONJ
fnp-6108	325	5	lateral	lateral	ADJ
fnp-6108	325	6	-	-	PUNCT
fnp-6108	325	7	temporal	temporal	ADJ
fnp-6108	325	8	-	-	PUNCT
fnp-6108	325	9	subtype	subtype	NOUN
fnp-6108	325	10	participants	participant	NOUN
fnp-6108	325	11	performed	perform	VERB
fnp-6108	325	12	worse	bad	ADJ
fnp-6108	325	13	on	on	ADP
fnp-6108	325	14	adas	adas	PROPN
fnp-6108	325	15	-	-	PUNCT
fnp-6108	325	16	cog	cog	PROPN
fnp-6108	325	17	delayed	delay	VERB
fnp-6108	325	18	recall	recall	NOUN
fnp-6108	325	19	and	and	CCONJ
fnp-6108	325	20	mmse	mmse	NOUN
fnp-6108	325	21	compared	compare	VERB
fnp-6108	325	22	to	to	ADP
fnp-6108	325	23	the	the	DET
fnp-6108	325	24	mtl	mtl	PROPN
fnp-6108	325	25	-	-	PUNCT
fnp-6108	325	26	sparing	sparing	ADJ
fnp-6108	325	27	and	and	CCONJ
fnp-6108	325	28	limbic	limbic	ADJ
fnp-6108	325	29	-	-	PUNCT
fnp-6108	325	30	subtype	subtype	NOUN
fnp-6108	325	31	over	over	ADP
fnp-6108	325	32	time	time	NOUN
fnp-6108	325	33	,	,	PUNCT
fnp-6108	325	34	respectively	respectively	ADV
fnp-6108	325	35	.	.	PUNCT
fnp-6108	326	1	subtype	subtype	NOUN
fnp-6108	326	2	-	-	PUNCT
fnp-6108	326	3	specific	specific	ADJ
fnp-6108	326	4	patterns	pattern	NOUN
fnp-6108	326	5	of	of	ADP
fnp-6108	326	6	local	local	ADJ
fnp-6108	326	7	and	and	CCONJ
fnp-6108	326	8	global	global	ADJ
fnp-6108	326	9	fmri	fmri	PROPN
fnp-6108	326	10	connectivity	connectivity	NOUN
fnp-6108	326	11	were	be	AUX
fnp-6108	326	12	evident	evident	ADJ
fnp-6108	326	13	,	,	PUNCT
fnp-6108	326	14	but	but	CCONJ
fnp-6108	326	15	no	no	DET
fnp-6108	326	16	genetic	genetic	ADJ
fnp-6108	326	17	risk	risk	NOUN
fnp-6108	326	18	factors	factor	NOUN
fnp-6108	326	19	survived	survive	VERB
fnp-6108	326	20	fdr	fdr	PROPN
fnp-6108	326	21	correction	correction	NOUN
fnp-6108	326	22	.	.	PUNCT
fnp-6108	327	1	conclusions	conclusion	NOUN
fnp-6108	327	2	:	:	PUNCT
fnp-6108	327	3	in	in	ADP
fnp-6108	327	4	a	a	DET
fnp-6108	327	5	large	large	ADJ
fnp-6108	327	6	single	single	ADJ
fnp-6108	327	7	-	-	PUNCT
fnp-6108	327	8	site	site	NOUN
fnp-6108	327	9	dataset	dataset	NOUN
fnp-6108	327	10	,	,	PUNCT
fnp-6108	327	11	we	we	PRON
fnp-6108	327	12	confirm	confirm	VERB
fnp-6108	327	13	and	and	CCONJ
fnp-6108	327	14	extend	extend	VERB
fnp-6108	327	15	findings	finding	NOUN
fnp-6108	327	16	that	that	SCONJ
fnp-6108	327	17	spatiotemporal	spatiotemporal	ADJ
fnp-6108	327	18	subtypes	subtype	NOUN
fnp-6108	327	19	of	of	ADP
fnp-6108	327	20	tau	tau	PROPN
fnp-6108	327	21	burden	burden	NOUN
fnp-6108	327	22	are	be	AUX
fnp-6108	327	23	differentiated	differentiate	VERB
fnp-6108	327	24	by	by	ADP
fnp-6108	327	25	demographics	demographic	NOUN
fnp-6108	327	26	and	and	CCONJ
fnp-6108	327	27	risk	risk	NOUN
fnp-6108	327	28	-	-	PUNCT
fnp-6108	327	29	factors	factor	NOUN
fnp-6108	327	30	.	.	PUNCT
fnp-6108	328	1	cortical	cortical	ADJ
fnp-6108	328	2	atrophy	atrophy	NOUN
fnp-6108	328	3	patterns	pattern	NOUN
fnp-6108	328	4	are	be	AUX
fnp-6108	328	5	mostly	mostly	ADV
fnp-6108	328	6	consistent	consistent	ADJ
fnp-6108	328	7	with	with	ADP
fnp-6108	328	8	the	the	DET
fnp-6108	328	9	distribution	distribution	NOUN
fnp-6108	328	10	of	of	ADP
fnp-6108	328	11	tau	tau	PROPN
fnp-6108	328	12	burden	burden	NOUN
fnp-6108	328	13	.	.	PUNCT
fnp-6108	329	1	the	the	DET
fnp-6108	329	2	lateral	lateral	ADJ
fnp-6108	329	3	-	-	PUNCT
fnp-6108	329	4	temporal	temporal	ADJ
fnp-6108	329	5	-	-	PUNCT
fnp-6108	329	6	subtype	subtype	NOUN
fnp-6108	329	7	showed	show	VERB
fnp-6108	329	8	higher	high	ADJ
fnp-6108	329	9	tau	tau	NOUN
fnp-6108	329	10	burden	burden	NOUN
fnp-6108	329	11	and	and	CCONJ
fnp-6108	329	12	increased	increase	VERB
fnp-6108	329	13	csf	csf	ADJ
fnp-6108	329	14	markers	marker	NOUN
fnp-6108	329	15	of	of	ADP
fnp-6108	329	16	neurodegeneration	neurodegeneration	NOUN
fnp-6108	329	17	,	,	PUNCT
fnp-6108	329	18	in	in	ADP
fnp-6108	329	19	line	line	NOUN
fnp-6108	329	20	with	with	ADP
fnp-6108	329	21	the	the	DET
fnp-6108	329	22	volume	volume	NOUN
fnp-6108	329	23	loss	loss	NOUN
fnp-6108	329	24	and	and	CCONJ
fnp-6108	329	25	cognitive	cognitive	ADJ
fnp-6108	329	26	decline	decline	NOUN
fnp-6108	329	27	.	.	PUNCT
fnp-6108	329	28	  	  	SPACE
fnp-6108	330	1	free	free	ADJ
fnp-6108	330	2	neuropathol	neuropathol	NOUN
fnp-6108	330	3	5:30:34	5:30:34	NUM
fnp-6108	330	4	clinical	clinical	ADJ
fnp-6108	330	5	and	and	CCONJ
fnp-6108	330	6	imaging	imaging	NOUN
fnp-6108	330	7	signatures	signature	NOUN
fnp-6108	330	8	of	of	ADP
fnp-6108	330	9	late	late	ADV
fnp-6108	330	10	:	:	PUNCT
fnp-6108	330	11	developing	develop	VERB
fnp-6108	330	12	a	a	DET
fnp-6108	330	13	diagnostic	diagnostic	ADJ
fnp-6108	330	14	framework	framework	NOUN
fnp-6108	330	15	david	david	PROPN
fnp-6108	330	16	a.	a.	PROPN
fnp-6108	330	17	wolk1–5	wolk1–5	PROPN
fnp-6108	330	18	alzheimer	alzheimer	PROPN
fnp-6108	330	19	’s	’s	PART
fnp-6108	330	20	disease	disease	PROPN
fnp-6108	330	21	research	research	NOUN
fnp-6108	330	22	center	center	NOUN
fnp-6108	330	23	,	,	PUNCT
fnp-6108	330	24	university	university	NOUN
fnp-6108	330	25	of	of	ADP
fnp-6108	330	26	pennsylvania	pennsylvania	PROPN
fnp-6108	330	27	,	,	PUNCT
fnp-6108	330	28	philadelphia	philadelphia	PROPN
fnp-6108	330	29	,	,	PUNCT
fnp-6108	330	30	pa	pa	PROPN
fnp-6108	330	31	,	,	PUNCT
fnp-6108	330	32	usa	usa	PROPN
fnp-6108	330	33	penn	penn	PROPN
fnp-6108	330	34	institute	institute	PROPN
fnp-6108	330	35	on	on	ADP
fnp-6108	330	36	aging	aging	NOUN
fnp-6108	330	37	,	,	PUNCT
fnp-6108	330	38	university	university	NOUN
fnp-6108	330	39	of	of	ADP
fnp-6108	330	40	pennsylvania	pennsylvania	PROPN
fnp-6108	330	41	,	,	PUNCT
fnp-6108	330	42	philadelphia	philadelphia	PROPN
fnp-6108	330	43	,	,	PUNCT
fnp-6108	330	44	pa	pa	PROPN
fnp-6108	330	45	,	,	PUNCT
fnp-6108	330	46	usa	usa	PROPN
fnp-6108	330	47	penn	penn	PROPN
fnp-6108	330	48	memory	memory	PROPN
fnp-6108	330	49	center	center	PROPN
fnp-6108	330	50	,	,	PUNCT
fnp-6108	330	51	university	university	NOUN
fnp-6108	330	52	of	of	ADP
fnp-6108	330	53	pennsylvania	pennsylvania	PROPN
fnp-6108	330	54	,	,	PUNCT
fnp-6108	330	55	philadelphia	philadelphia	PROPN
fnp-6108	330	56	,	,	PUNCT
fnp-6108	330	57	pa	pa	PROPN
fnp-6108	330	58	,	,	PUNCT
fnp-6108	330	59	usa	usa	PROPN
fnp-6108	330	60	cognitive	cognitive	ADJ
fnp-6108	330	61	neurology	neurology	NOUN
fnp-6108	330	62	,	,	PUNCT
fnp-6108	330	63	university	university	PROPN
fnp-6108	330	64	of	of	ADP
fnp-6108	330	65	pennsylvania	pennsylvania	PROPN
fnp-6108	330	66	,	,	PUNCT
fnp-6108	330	67	philadelphia	philadelphia	PROPN
fnp-6108	330	68	,	,	PUNCT
fnp-6108	330	69	pa	pa	PROPN
fnp-6108	330	70	,	,	PUNCT
fnp-6108	330	71	usa	usa	PROPN
fnp-6108	330	72	department	department	PROPN
fnp-6108	330	73	of	of	ADP
fnp-6108	330	74	neurology	neurology	NOUN
fnp-6108	330	75	,	,	PUNCT
fnp-6108	330	76	university	university	PROPN
fnp-6108	330	77	of	of	ADP
fnp-6108	330	78	pennsylvania	pennsylvania	PROPN
fnp-6108	330	79	,	,	PUNCT
fnp-6108	330	80	philadelphia	philadelphia	PROPN
fnp-6108	330	81	,	,	PUNCT
fnp-6108	330	82	pa	pa	PROPN
fnp-6108	330	83	,	,	PUNCT
fnp-6108	330	84	usa	usa	PROPN
fnp-6108	330	85	objective	objective	NOUN
fnp-6108	330	86	:	:	PUNCT
fnp-6108	330	87	the	the	DET
fnp-6108	330	88	goal	goal	NOUN
fnp-6108	330	89	of	of	ADP
fnp-6108	330	90	this	this	DET
fnp-6108	330	91	talk	talk	NOUN
fnp-6108	330	92	will	will	AUX
fnp-6108	330	93	be	be	AUX
fnp-6108	330	94	to	to	PART
fnp-6108	330	95	provide	provide	VERB
fnp-6108	330	96	a	a	DET
fnp-6108	330	97	brief	brief	ADJ
fnp-6108	330	98	review	review	NOUN
fnp-6108	330	99	of	of	ADP
fnp-6108	330	100	the	the	DET
fnp-6108	330	101	literature	literature	NOUN
fnp-6108	330	102	focused	focus	VERB
fnp-6108	330	103	on	on	ADP
fnp-6108	330	104	clinical	clinical	ADJ
fnp-6108	330	105	and	and	CCONJ
fnp-6108	330	106	biomarker	biomarker	NOUN
fnp-6108	330	107	features	feature	NOUN
fnp-6108	330	108	of	of	ADP
fnp-6108	330	109	limbic	limbic	ADJ
fnp-6108	330	110	-	-	PUNCT
fnp-6108	330	111	predominant	predominant	ADJ
fnp-6108	330	112	age	age	NOUN
fnp-6108	330	113	-	-	PUNCT
fnp-6108	330	114	related	relate	VERB
fnp-6108	330	115	tdp-43	tdp-43	NOUN
fnp-6108	330	116	encephalopathy	encephalopathy	ADJ
fnp-6108	330	117	(	(	PUNCT
fnp-6108	330	118	late	late	ADJ
fnp-6108	330	119	)	)	PUNCT
fnp-6108	330	120	.	.	PUNCT
fnp-6108	331	1	this	this	DET
fnp-6108	331	2	review	review	NOUN
fnp-6108	331	3	will	will	AUX
fnp-6108	331	4	emphasize	emphasize	VERB
fnp-6108	331	5	the	the	DET
fnp-6108	331	6	clinical	clinical	ADJ
fnp-6108	331	7	importance	importance	NOUN
fnp-6108	331	8	of	of	ADP
fnp-6108	331	9	this	this	DET
fnp-6108	331	10	condition	condition	NOUN
fnp-6108	331	11	,	,	PUNCT
fnp-6108	331	12	particularly	particularly	ADV
fnp-6108	331	13	in	in	ADP
fnp-6108	331	14	the	the	DET
fnp-6108	331	15	context	context	NOUN
fnp-6108	331	16	of	of	ADP
fnp-6108	331	17	alzheimer	alzheimer	PROPN
fnp-6108	331	18	’s	’s	PART
fnp-6108	331	19	disease	disease	NOUN
fnp-6108	331	20	immunotherapies	immunotherapie	VERB
fnp-6108	331	21	,	,	PUNCT
fnp-6108	331	22	as	as	ADV
fnp-6108	331	23	well	well	ADV
fnp-6108	331	24	as	as	ADP
fnp-6108	331	25	a	a	DET
fnp-6108	331	26	newly	newly	ADV
fnp-6108	331	27	proposed	propose	VERB
fnp-6108	331	28	framework	framework	NOUN
fnp-6108	331	29	for	for	ADP
fnp-6108	331	30	clinical	clinical	ADJ
fnp-6108	331	31	identification	identification	NOUN
fnp-6108	331	32	.	.	PUNCT
fnp-6108	332	1	materials	material	NOUN
fnp-6108	332	2	and	and	CCONJ
fnp-6108	332	3	methods	method	NOUN
fnp-6108	332	4	:	:	PUNCT
fnp-6108	332	5	the	the	DET
fnp-6108	332	6	speaker	speaker	NOUN
fnp-6108	332	7	will	will	AUX
fnp-6108	332	8	review	review	VERB
fnp-6108	332	9	the	the	DET
fnp-6108	332	10	existing	exist	VERB
fnp-6108	332	11	literature	literature	NOUN
fnp-6108	332	12	focused	focus	VERB
fnp-6108	332	13	primarily	primarily	ADV
fnp-6108	332	14	on	on	ADP
fnp-6108	332	15	clinical	clinical	ADJ
fnp-6108	332	16	and	and	CCONJ
fnp-6108	332	17	neuroimaging	neuroimaging	ADJ
fnp-6108	332	18	studies	study	NOUN
fnp-6108	332	19	in	in	ADP
fnp-6108	332	20	autopsy	autopsy	ADJ
fnp-6108	332	21	-	-	PUNCT
fnp-6108	332	22	confirmed	confirm	VERB
fnp-6108	332	23	cases	case	NOUN
fnp-6108	332	24	with	with	ADP
fnp-6108	332	25	an	an	DET
fnp-6108	332	26	emphasis	emphasis	NOUN
fnp-6108	332	27	on	on	ADP
fnp-6108	332	28	how	how	SCONJ
fnp-6108	332	29	these	these	DET
fnp-6108	332	30	features	feature	NOUN
fnp-6108	332	31	overlap	overlap	VERB
fnp-6108	332	32	and	and	CCONJ
fnp-6108	332	33	differ	differ	VERB
fnp-6108	332	34	from	from	ADP
fnp-6108	332	35	alzheimer	alzheimer	PROPN
fnp-6108	332	36	’s	’s	PART
fnp-6108	332	37	disease	disease	NOUN
fnp-6108	332	38	,	,	PUNCT
fnp-6108	332	39	for	for	ADP
fnp-6108	332	40	which	which	PRON
fnp-6108	332	41	it	it	PRON
fnp-6108	332	42	is	be	AUX
fnp-6108	332	43	a	a	DET
fnp-6108	332	44	frequent	frequent	ADJ
fnp-6108	332	45	mimic	mimic	NOUN
fnp-6108	332	46	.	.	PUNCT
fnp-6108	333	1	a	a	DET
fnp-6108	333	2	particular	particular	ADJ
fnp-6108	333	3	focus	focus	NOUN
fnp-6108	333	4	will	will	AUX
fnp-6108	333	5	be	be	AUX
fnp-6108	333	6	on	on	ADP
fnp-6108	333	7	work	work	NOUN
fnp-6108	333	8	from	from	ADP
fnp-6108	333	9	the	the	DET
fnp-6108	333	10	speaker	speaker	NOUN
fnp-6108	333	11	’s	’s	PART
fnp-6108	333	12	laboratory	laboratory	NOUN
fnp-6108	333	13	,	,	PUNCT
fnp-6108	333	14	including	include	VERB
fnp-6108	333	15	both	both	CCONJ
fnp-6108	333	16	ante	ante	NOUN
fnp-6108	333	17	-	-	PUNCT
fnp-6108	333	18	mortem	mortem	NOUN
fnp-6108	333	19	and	and	CCONJ
fnp-6108	333	20	post	post	ADJ
fnp-6108	333	21	-	-	ADJ
fnp-6108	333	22	mortem	mortem	ADJ
fnp-6108	333	23	mri	mri	NOUN
fnp-6108	333	24	imaging	imaging	NOUN
fnp-6108	333	25	to	to	PART
fnp-6108	333	26	determine	determine	VERB
fnp-6108	333	27	signatures	signature	NOUN
fnp-6108	333	28	of	of	ADP
fnp-6108	333	29	late	late	ADJ
fnp-6108	333	30	.	.	PUNCT
fnp-6108	334	1	results	result	NOUN
fnp-6108	334	2	:	:	PUNCT
fnp-6108	334	3	based	base	VERB
fnp-6108	334	4	on	on	ADP
fnp-6108	334	5	literature	literature	NOUN
fnp-6108	334	6	review	review	NOUN
fnp-6108	334	7	and	and	CCONJ
fnp-6108	334	8	consensus	consensus	NOUN
fnp-6108	334	9	from	from	ADP
fnp-6108	334	10	experts	expert	NOUN
fnp-6108	334	11	in	in	ADP
fnp-6108	334	12	the	the	DET
fnp-6108	334	13	field	field	NOUN
fnp-6108	334	14	,	,	PUNCT
fnp-6108	334	15	newly	newly	ADV
fnp-6108	334	16	proposed	propose	VERB
fnp-6108	334	17	diagnostic	diagnostic	ADJ
fnp-6108	334	18	criteria	criterion	NOUN
fnp-6108	334	19	will	will	AUX
fnp-6108	334	20	be	be	AUX
fnp-6108	334	21	presented	present	VERB
fnp-6108	334	22	for	for	ADP
fnp-6108	334	23	in	in	ADP
fnp-6108	334	24	vivo	vivo	ADJ
fnp-6108	334	25	detection	detection	NOUN
fnp-6108	334	26	of	of	ADP
fnp-6108	334	27	late	late	ADV
fnp-6108	334	28	in	in	ADP
fnp-6108	334	29	the	the	DET
fnp-6108	334	30	context	context	NOUN
fnp-6108	334	31	of	of	ADP
fnp-6108	334	32	it	it	PRON
fnp-6108	334	33	being	be	AUX
fnp-6108	334	34	the	the	DET
fnp-6108	334	35	primary	primary	ADJ
fnp-6108	334	36	driver	driver	NOUN
fnp-6108	334	37	of	of	ADP
fnp-6108	334	38	clinical	clinical	ADJ
fnp-6108	334	39	presentation	presentation	NOUN
fnp-6108	334	40	and	and	CCONJ
fnp-6108	334	41	when	when	SCONJ
fnp-6108	334	42	it	it	PRON
fnp-6108	334	43	is	be	AUX
fnp-6108	334	44	concomitant	concomitant	ADJ
fnp-6108	334	45	with	with	ADP
fnp-6108	334	46	alzheimer	alzheimer	PROPN
fnp-6108	334	47	’s	’s	PART
fnp-6108	334	48	disease	disease	NOUN
fnp-6108	334	49	pathology	pathology	PROPN
fnp-6108	334	50	.	.	PUNCT
fnp-6108	335	1	supportive	supportive	ADJ
fnp-6108	335	2	imaging	imaging	NOUN
fnp-6108	335	3	features	feature	NOUN
fnp-6108	335	4	,	,	PUNCT
fnp-6108	335	5	including	include	VERB
fnp-6108	335	6	topography	topography	NOUN
fnp-6108	335	7	of	of	ADP
fnp-6108	335	8	medial	medial	ADJ
fnp-6108	335	9	temporal	temporal	ADJ
fnp-6108	335	10	lobe	lobe	ADJ
fnp-6108	335	11	atrophy	atrophy	NOUN
fnp-6108	335	12	and	and	CCONJ
fnp-6108	335	13	relationship	relationship	NOUN
fnp-6108	335	14	to	to	ADP
fnp-6108	335	15	tau	tau	PROPN
fnp-6108	335	16	pathology	pathology	NOUN
fnp-6108	335	17	(	(	PUNCT
fnp-6108	335	18	i.e.	i.e.	X
fnp-6108	335	19	tau	tau	NOUN
fnp-6108	335	20	-	-	PUNCT
fnp-6108	335	21	neurodegeneration	neurodegeneration	NOUN
fnp-6108	335	22	mismatch	mismatch	NOUN
fnp-6108	335	23	)	)	PUNCT
fnp-6108	335	24	,	,	PUNCT
fnp-6108	335	25	will	will	AUX
fnp-6108	335	26	be	be	AUX
fnp-6108	335	27	highlighted	highlight	VERB
fnp-6108	335	28	.	.	PUNCT
fnp-6108	336	1	conclusion	conclusion	NOUN
fnp-6108	336	2	:	:	PUNCT
fnp-6108	336	3	emerging	emerge	VERB
fnp-6108	336	4	work	work	NOUN
fnp-6108	336	5	on	on	ADP
fnp-6108	336	6	the	the	DET
fnp-6108	336	7	recently	recently	ADV
fnp-6108	336	8	codified	codify	VERB
fnp-6108	336	9	pathological	pathological	ADJ
fnp-6108	336	10	entity	entity	NOUN
fnp-6108	336	11	of	of	ADP
fnp-6108	336	12	late	late	ADJ
fnp-6108	336	13	has	have	AUX
fnp-6108	336	14	matured	mature	VERB
fnp-6108	336	15	to	to	ADP
fnp-6108	336	16	where	where	SCONJ
fnp-6108	336	17	a	a	DET
fnp-6108	336	18	probabilistic	probabilistic	NOUN
fnp-6108	336	19	in	in	ADP
fnp-6108	336	20	vivo	vivo	ADJ
fnp-6108	336	21	diagnosis	diagnosis	NOUN
fnp-6108	336	22	can	can	AUX
fnp-6108	336	23	be	be	AUX
fnp-6108	336	24	made	make	VERB
fnp-6108	336	25	,	,	PUNCT
fnp-6108	336	26	providing	provide	VERB
fnp-6108	336	27	an	an	DET
fnp-6108	336	28	important	important	ADJ
fnp-6108	336	29	platform	platform	NOUN
fnp-6108	336	30	for	for	ADP
fnp-6108	336	31	future	future	ADJ
fnp-6108	336	32	research	research	NOUN
fnp-6108	336	33	.	.	PUNCT
fnp-6108	337	1	among	among	ADP
fnp-6108	337	2	other	other	ADJ
fnp-6108	337	3	benefits	benefit	NOUN
fnp-6108	337	4	,	,	PUNCT
fnp-6108	337	5	such	such	ADJ
fnp-6108	337	6	clinical	clinical	ADJ
fnp-6108	337	7	classification	classification	NOUN
fnp-6108	337	8	will	will	AUX
fnp-6108	337	9	help	help	VERB
fnp-6108	337	10	advance	advance	VERB
fnp-6108	337	11	development	development	NOUN
fnp-6108	337	12	of	of	ADP
fnp-6108	337	13	molecular	molecular	ADJ
fnp-6108	337	14	biomarkers	biomarker	NOUN
fnp-6108	337	15	for	for	ADP
fnp-6108	337	16	tdp-43	tdp-43	PROPN
fnp-6108	337	17	and	and	CCONJ
fnp-6108	337	18	therapeutic	therapeutic	ADJ
fnp-6108	337	19	trials	trial	NOUN
fnp-6108	337	20	specifically	specifically	ADV
fnp-6108	337	21	targeting	target	VERB
fnp-6108	337	22	this	this	DET
fnp-6108	337	23	condition	condition	NOUN
fnp-6108	337	24	.	.	PUNCT
fnp-6108	338	1	copyright	copyright	NOUN
fnp-6108	338	2	:	:	PUNCT
fnp-6108	338	3	©	©	PROPN
fnp-6108	338	4	2024	2024	NUM
fnp-6108	338	5	the	the	DET
fnp-6108	338	6	author(s	author(s	NOUN
fnp-6108	338	7	)	)	PUNCT
fnp-6108	338	8	.	.	PUNCT
fnp-6108	339	1	this	this	PRON
fnp-6108	339	2	is	be	AUX
fnp-6108	339	3	an	an	DET
fnp-6108	339	4	open	open	ADJ
fnp-6108	339	5	access	access	NOUN
fnp-6108	339	6	article	article	NOUN
fnp-6108	339	7	distributed	distribute	VERB
fnp-6108	339	8	under	under	ADP
fnp-6108	339	9	the	the	DET
fnp-6108	339	10	terms	term	NOUN
fnp-6108	339	11	of	of	ADP
fnp-6108	339	12	the	the	DET
fnp-6108	339	13	creative	creative	ADJ
fnp-6108	339	14	commons	common	NOUN
fnp-6108	339	15	attribution	attribution	NOUN
fnp-6108	339	16	4.0	4.0	NUM
fnp-6108	339	17	international	international	ADJ
fnp-6108	339	18	license	license	NOUN
fnp-6108	339	19	(	(	PUNCT
fnp-6108	339	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-6108	339	21	)	)	PUNCT
fnp-6108	339	22	,	,	PUNCT
fnp-6108	339	23	which	which	PRON
fnp-6108	339	24	permits	permit	VERB
fnp-6108	339	25	unrestricted	unrestricted	ADJ
fnp-6108	339	26	use	use	NOUN
fnp-6108	339	27	,	,	PUNCT
fnp-6108	339	28	distribution	distribution	NOUN
fnp-6108	339	29	,	,	PUNCT
fnp-6108	339	30	and	and	CCONJ
fnp-6108	339	31	reproduction	reproduction	NOUN
fnp-6108	339	32	in	in	ADP
fnp-6108	339	33	any	any	DET
fnp-6108	339	34	medium	medium	NOUN
fnp-6108	339	35	,	,	PUNCT
fnp-6108	339	36	provided	provide	VERB
fnp-6108	339	37	the	the	DET
fnp-6108	339	38	original	original	ADJ
fnp-6108	339	39	author	author	NOUN
fnp-6108	339	40	and	and	CCONJ
fnp-6108	339	41	source	source	NOUN
fnp-6108	339	42	are	be	AUX
fnp-6108	339	43	credited	credit	VERB
fnp-6108	339	44	,	,	PUNCT
fnp-6108	339	45	a	a	DET
fnp-6108	339	46	link	link	NOUN
fnp-6108	339	47	to	to	ADP
fnp-6108	339	48	the	the	DET
fnp-6108	339	49	creative	creative	ADJ
fnp-6108	339	50	commons	common	NOUN
fnp-6108	339	51	license	license	NOUN
fnp-6108	339	52	is	be	AUX
fnp-6108	339	53	provided	provide	VERB
fnp-6108	339	54	,	,	PUNCT
fnp-6108	339	55	and	and	CCONJ
fnp-6108	339	56	any	any	DET
fnp-6108	339	57	changes	change	NOUN
fnp-6108	339	58	are	be	AUX
fnp-6108	339	59	indicated	indicate	VERB
fnp-6108	339	60	.	.	PUNCT
fnp-6108	340	1	the	the	DET
fnp-6108	340	2	creative	creative	ADJ
fnp-6108	340	3	commons	common	NOUN
fnp-6108	340	4	public	public	ADJ
fnp-6108	340	5	domain	domain	NOUN
fnp-6108	340	6	dedication	dedication	NOUN
fnp-6108	340	7	waiver	waiver	NOUN
fnp-6108	340	8	(	(	PUNCT
fnp-6108	340	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-6108	340	10	)	)	PUNCT
fnp-6108	340	11	applies	apply	VERB
fnp-6108	340	12	to	to	ADP
fnp-6108	340	13	the	the	DET
fnp-6108	340	14	data	datum	NOUN
fnp-6108	340	15	made	make	VERB
fnp-6108	340	16	available	available	ADJ
fnp-6108	340	17	in	in	ADP
fnp-6108	340	18	this	this	DET
fnp-6108	340	19	article	article	NOUN
fnp-6108	340	20	,	,	PUNCT
fnp-6108	340	21	unless	unless	SCONJ
fnp-6108	340	22	otherwise	otherwise	ADV
fnp-6108	340	23	stated	state	VERB
fnp-6108	340	24	.	.	PUNCT