id	sid	tid	token	lemma	pos
fnp-6285	1	1	66th	66th	ADJ
fnp-6285	1	2	meeting	meeting	NOUN
fnp-6285	1	3	of	of	ADP
fnp-6285	1	4	the	the	DET
fnp-6285	1	5	french	french	ADJ
fnp-6285	1	6	society	society	NOUN
fnp-6285	1	7	of	of	ADP
fnp-6285	1	8	neuropathology	neuropathology	NOUN
fnp-6285	1	9	meeting	meeting	NOUN
fnp-6285	1	10	abstracts	abstract	NOUN
fnp-6285	1	11	,	,	PUNCT
fnp-6285	1	12	december	december	PROPN
fnp-6285	1	13	6th	6th	NOUN
fnp-6285	1	14	.	.	PUNCT
fnp-6285	2	1	2024	2024	NUM
fnp-6285	2	2	feel	feel	VERB
fnp-6285	2	3	free	free	ADJ
fnp-6285	2	4	to	to	PART
fnp-6285	2	5	add	add	VERB
fnp-6285	2	6	comments	comment	NOUN
fnp-6285	2	7	by	by	ADP
fnp-6285	2	8	clicking	click	VERB
fnp-6285	2	9	these	these	DET
fnp-6285	2	10	icons	icon	NOUN
fnp-6285	2	11	on	on	ADP
fnp-6285	2	12	the	the	DET
fnp-6285	2	13	sidebar	sidebar	NOUN
fnp-6285	2	14	free	free	ADJ
fnp-6285	2	15	neuropathology	neuropathology	NOUN
fnp-6285	2	16	6:2	6:2	NUM
fnp-6285	2	17	(	(	PUNCT
fnp-6285	2	18	2025	2025	NUM
fnp-6285	2	19	)	)	PUNCT
fnp-6285	2	20	meeting	meeting	NOUN
fnp-6285	2	21	abstracts	abstract	VERB
fnp-6285	2	22	66th	66th	ADJ
fnp-6285	2	23	meeting	meeting	NOUN
fnp-6285	2	24	of	of	ADP
fnp-6285	2	25	the	the	DET
fnp-6285	2	26	french	french	ADJ
fnp-6285	2	27	society	society	NOUN
fnp-6285	2	28	of	of	ADP
fnp-6285	2	29	neuropathology	neuropathology	NOUN
fnp-6285	2	30	meeting	meeting	NOUN
fnp-6285	2	31	abstracts	abstract	NOUN
fnp-6285	2	32	december	december	PROPN
fnp-6285	2	33	6th	6th	NOUN
fnp-6285	2	34	,	,	PUNCT
fnp-6285	2	35	2024	2024	NUM
fnp-6285	2	36	hôpital	hôpital	PROPN
fnp-6285	2	37	pitié	pitié	PROPN
fnp-6285	2	38	salpêtrière	salpêtrière	PROPN
fnp-6285	2	39	,	,	PUNCT
fnp-6285	2	40	amphithéâtre	amphithéâtre	PROPN
fnp-6285	2	41	charcot	charcot	PROPN
fnp-6285	2	42	the	the	DET
fnp-6285	2	43	french	french	ADJ
fnp-6285	2	44	society	society	NOUN
fnp-6285	2	45	of	of	ADP
fnp-6285	2	46	neuropathology	neuropathology	NOUN
fnp-6285	2	47	was	be	AUX
fnp-6285	2	48	created	create	VERB
fnp-6285	2	49	in	in	ADP
fnp-6285	2	50	1989	1989	NUM
fnp-6285	2	51	,	,	PUNCT
fnp-6285	2	52	succeeding	succeed	VERB
fnp-6285	2	53	the	the	DET
fnp-6285	2	54	french	french	ADJ
fnp-6285	2	55	club	club	NOUN
fnp-6285	2	56	of	of	ADP
fnp-6285	2	57	neuropathology	neuropathology	NOUN
fnp-6285	2	58	set	set	VERB
fnp-6285	2	59	up	up	ADP
fnp-6285	2	60	in	in	ADP
fnp-6285	2	61	1965	1965	NUM
fnp-6285	2	62	.	.	PUNCT
fnp-6285	2	63	  	  	SPACE
fnp-6285	3	1	submitted	submit	VERB
fnp-6285	3	2	:	:	PUNCT
fnp-6285	3	3	04	04	NUM
fnp-6285	3	4	december	december	PROPN
fnp-6285	3	5	2024	2024	NUM
fnp-6285	3	6	accepted	accept	VERB
fnp-6285	3	7	:	:	PUNCT
fnp-6285	3	8	05	05	NUM
fnp-6285	3	9	december	december	PROPN
fnp-6285	3	10	2024	2024	NUM
fnp-6285	3	11	published	publish	VERB
fnp-6285	3	12	:	:	PUNCT
fnp-6285	3	13	29	29	NUM
fnp-6285	3	14	january	january	NOUN
fnp-6285	3	15	2025	2025	NUM
fnp-6285	3	16	https://doi.org/10.17879/freeneuropathology-2025-6285	https://doi.org/10.17879/freeneuropathology-2025-6285	PUNCT
fnp-6285	4	1	keywords	keyword	NOUN
fnp-6285	4	2	:	:	PUNCT
fnp-6285	4	3	french	french	ADJ
fnp-6285	4	4	society	society	NOUN
fnp-6285	4	5	of	of	ADP
fnp-6285	4	6	neuropathology	neuropathology	NOUN
fnp-6285	4	7	,	,	PUNCT
fnp-6285	4	8	sfnp	sfnp	PROPN
fnp-6285	4	9	,	,	PUNCT
fnp-6285	4	10	meeting	meet	VERB
fnp-6285	4	11	abstracts	abstract	NOUN
fnp-6285	4	12	,	,	PUNCT
fnp-6285	4	13	66th	66th	ADJ
fnp-6285	4	14	meeting	meeting	NOUN
fnp-6285	4	15	dec	dec	PROPN
fnp-6285	4	16	.	.	PROPN
fnp-6285	4	17	2024	2024	NUM
fnp-6285	4	18	  	  	SPACE
fnp-6285	4	19	free	free	ADJ
fnp-6285	4	20	neuropathol	neuropathol	NOUN
fnp-6285	4	21	6:2:2	6:2:2	NUM
fnp-6285	4	22	cerebrospinal	cerebrospinal	ADJ
fnp-6285	4	23	fluid	fluid	NOUN
fnp-6285	4	24	processing	processing	NOUN
fnp-6285	4	25	in	in	ADP
fnp-6285	4	26	cytology	cytology	NOUN
fnp-6285	4	27	and	and	CCONJ
fnp-6285	4	28	pathology	pathology	NOUN
fnp-6285	4	29	laboratories	laboratory	NOUN
fnp-6285	4	30	:	:	PUNCT
fnp-6285	4	31	changes	change	NOUN
fnp-6285	4	32	of	of	ADP
fnp-6285	4	33	practice	practice	NOUN
fnp-6285	4	34	plu	plu	PROPN
fnp-6285	4	35	i1,2	i1,2	PROPN
fnp-6285	4	36	,	,	PUNCT
fnp-6285	4	37	tran	tran	NOUN
fnp-6285	4	38	s1	s1	PROPN
fnp-6285	4	39	,	,	PUNCT
fnp-6285	4	40	boluda	boluda	PROPN
fnp-6285	4	41	s1,2	s1,2	PROPN
fnp-6285	4	42	,	,	PUNCT
fnp-6285	4	43	privat	privat	ADJ
fnp-6285	4	44	n2	n2	NOUN
fnp-6285	4	45	,	,	PUNCT
fnp-6285	4	46	seilhean	seilhean	ADJ
fnp-6285	4	47	d1,2	d1,2	ADJ
fnp-6285	4	48	département	département	X
fnp-6285	4	49	de	de	X
fnp-6285	4	50	neuropathologie	neuropathologie	NOUN
fnp-6285	4	51	,	,	PUNCT
fnp-6285	4	52	hôpital	hôpital	PROPN
fnp-6285	4	53	pitié	pitié	PROPN
fnp-6285	4	54	salpêtrière	salpêtrière	PROPN
fnp-6285	4	55	,	,	PUNCT
fnp-6285	4	56	gh.ap	gh.ap	PROPN
fnp-6285	4	57	-	-	PUNCT
fnp-6285	4	58	hp	hp	PROPN
fnp-6285	4	59	sorbonne	sorbonne	PROPN
fnp-6285	4	60	université	université	PROPN
fnp-6285	4	61	,	,	PUNCT
fnp-6285	4	62	paris	paris	PROPN
fnp-6285	4	63	,	,	PUNCT
fnp-6285	4	64	france	france	PROPN
fnp-6285	4	65	sorbonne	sorbonne	PROPN
fnp-6285	4	66	université	université	PROPN
fnp-6285	4	67	,	,	PUNCT
fnp-6285	4	68	brain	brain	NOUN
fnp-6285	4	69	institute	institute	PROPN
fnp-6285	4	70	,	,	PUNCT
fnp-6285	4	71	inserm	inserm	PROPN
fnp-6285	4	72	,	,	PUNCT
fnp-6285	4	73	umrs	umrs	ADJ
fnp-6285	4	74	1127	1127	NUM
fnp-6285	4	75	;	;	PUNCT
fnp-6285	4	76	cnrs	cnrs	NOUN
fnp-6285	4	77	,	,	PUNCT
fnp-6285	4	78	umr	umr	PROPN
fnp-6285	4	79	7225	7225	NUM
fnp-6285	4	80	,	,	PUNCT
fnp-6285	4	81	paris	paris	PROPN
fnp-6285	4	82	,	,	PUNCT
fnp-6285	4	83	france	france	PROPN
fnp-6285	4	84	the	the	DET
fnp-6285	4	85	handling	handling	NOUN
fnp-6285	4	86	and	and	CCONJ
fnp-6285	4	87	analysis	analysis	NOUN
fnp-6285	4	88	of	of	ADP
fnp-6285	4	89	cerebrospinal	cerebrospinal	ADJ
fnp-6285	4	90	fluid	fluid	NOUN
fnp-6285	4	91	(	(	PUNCT
fnp-6285	4	92	csf	csf	NOUN
fnp-6285	4	93	)	)	PUNCT
fnp-6285	4	94	in	in	ADP
fnp-6285	4	95	cytology	cytology	NOUN
fnp-6285	4	96	and	and	CCONJ
fnp-6285	4	97	pathology	pathology	NOUN
fnp-6285	4	98	laboratories	laboratory	NOUN
fnp-6285	4	99	require	require	VERB
fnp-6285	4	100	safety	safety	NOUN
fnp-6285	4	101	measures	measure	NOUN
fnp-6285	4	102	,	,	PUNCT
fnp-6285	4	103	due	due	ADP
fnp-6285	4	104	to	to	ADP
fnp-6285	4	105	the	the	DET
fnp-6285	4	106	potential	potential	ADJ
fnp-6285	4	107	risk	risk	NOUN
fnp-6285	4	108	of	of	ADP
fnp-6285	4	109	infection	infection	NOUN
fnp-6285	4	110	.	.	PUNCT
fnp-6285	5	1	the	the	DET
fnp-6285	5	2	2004	2004	NUM
fnp-6285	5	3	french	french	ADJ
fnp-6285	5	4	safety	safety	NOUN
fnp-6285	5	5	regulations	regulation	NOUN
fnp-6285	5	6	recommended	recommend	VERB
fnp-6285	5	7	that	that	SCONJ
fnp-6285	5	8	the	the	DET
fnp-6285	5	9	csf	csf	NOUN
fnp-6285	5	10	of	of	ADP
fnp-6285	5	11	patients	patient	NOUN
fnp-6285	5	12	suspected	suspect	VERB
fnp-6285	5	13	of	of	ADP
fnp-6285	5	14	having	have	VERB
fnp-6285	5	15	creutzfeldt	creutzfeldt	ADJ
fnp-6285	5	16	-	-	PUNCT
fnp-6285	5	17	jakob	jakob	ADJ
fnp-6285	5	18	disease	disease	NOUN
fnp-6285	5	19	was	be	AUX
fnp-6285	5	20	subject	subject	ADJ
fnp-6285	5	21	to	to	ADP
fnp-6285	5	22	maximum	maximum	ADJ
fnp-6285	5	23	precautions	precaution	NOUN
fnp-6285	5	24	,	,	PUNCT
fnp-6285	5	25	generally	generally	ADV
fnp-6285	5	26	implemented	implement	VERB
fnp-6285	5	27	in	in	ADP
fnp-6285	5	28	specialized	specialized	ADJ
fnp-6285	5	29	laboratories	laboratory	NOUN
fnp-6285	5	30	.	.	PUNCT
fnp-6285	6	1	since	since	SCONJ
fnp-6285	6	2	2020	2020	NUM
fnp-6285	6	3	,	,	PUNCT
fnp-6285	6	4	following	follow	VERB
fnp-6285	6	5	accidental	accidental	ADJ
fnp-6285	6	6	occupational	occupational	ADJ
fnp-6285	6	7	contamination	contamination	NOUN
fnp-6285	6	8	in	in	ADP
fnp-6285	6	9	research	research	NOUN
fnp-6285	6	10	laboratories	laboratory	NOUN
fnp-6285	6	11	,	,	PUNCT
fnp-6285	6	12	new	new	ADJ
fnp-6285	6	13	procedures	procedure	NOUN
fnp-6285	6	14	are	be	AUX
fnp-6285	6	15	being	be	AUX
fnp-6285	6	16	developed	develop	VERB
fnp-6285	6	17	.	.	PUNCT
fnp-6285	7	1	in	in	ADP
fnp-6285	7	2	november	november	PROPN
fnp-6285	7	3	2021	2021	NUM
fnp-6285	7	4	,	,	PUNCT
fnp-6285	7	5	the	the	DET
fnp-6285	7	6	uk	uk	PROPN
fnp-6285	7	7	’s	’s	PART
fnp-6285	7	8	advisory	advisory	ADJ
fnp-6285	7	9	committee	committee	NOUN
fnp-6285	7	10	for	for	ADP
fnp-6285	7	11	dangerous	dangerous	ADJ
fnp-6285	7	12	pathogens	pathogen	NOUN
fnp-6285	7	13	revised	revise	VERB
fnp-6285	7	14	its	its	PRON
fnp-6285	7	15	guidance	guidance	NOUN
fnp-6285	7	16	and	and	CCONJ
fnp-6285	7	17	considers	consider	VERB
fnp-6285	7	18	csf	csf	ADJ
fnp-6285	7	19	to	to	PART
fnp-6285	7	20	be	be	AUX
fnp-6285	7	21	a	a	DET
fnp-6285	7	22	low	low	ADJ
fnp-6285	7	23	-	-	PUNCT
fnp-6285	7	24	risk	risk	NOUN
fnp-6285	7	25	biofluid	biofluid	NOUN
fnp-6285	7	26	,	,	PUNCT
fnp-6285	7	27	allowing	allow	VERB
fnp-6285	7	28	it	it	PRON
fnp-6285	7	29	to	to	PART
fnp-6285	7	30	be	be	AUX
fnp-6285	7	31	handled	handle	VERB
fnp-6285	7	32	with	with	ADP
fnp-6285	7	33	only	only	ADJ
fnp-6285	7	34	general	general	ADJ
fnp-6285	7	35	laboratory	laboratory	NOUN
fnp-6285	7	36	hygiene	hygiene	NOUN
fnp-6285	7	37	and	and	CCONJ
fnp-6285	7	38	safety	safety	NOUN
fnp-6285	7	39	rules	rule	NOUN
fnp-6285	7	40	.	.	PUNCT
fnp-6285	8	1	based	base	VERB
fnp-6285	8	2	on	on	ADP
fnp-6285	8	3	uk	uk	PROPN
fnp-6285	8	4	guidelines	guideline	NOUN
fnp-6285	8	5	,	,	PUNCT
fnp-6285	8	6	we	we	PRON
fnp-6285	8	7	have	have	AUX
fnp-6285	8	8	updated	update	VERB
fnp-6285	8	9	our	our	PRON
fnp-6285	8	10	csf	csf	ADJ
fnp-6285	8	11	handling	handling	NOUN
fnp-6285	8	12	procedure	procedure	NOUN
fnp-6285	8	13	with	with	ADP
fnp-6285	8	14	a	a	DET
fnp-6285	8	15	single	single	ADJ
fnp-6285	8	16	circuit	circuit	NOUN
fnp-6285	8	17	applicable	applicable	ADJ
fnp-6285	8	18	to	to	ADP
fnp-6285	8	19	all	all	DET
fnp-6285	8	20	clinical	clinical	ADJ
fnp-6285	8	21	situations	situation	NOUN
fnp-6285	8	22	and	and	CCONJ
fnp-6285	8	23	achievable	achievable	ADJ
fnp-6285	8	24	in	in	ADP
fnp-6285	8	25	all	all	DET
fnp-6285	8	26	laboratories	laboratory	NOUN
fnp-6285	8	27	,	,	PUNCT
fnp-6285	8	28	bearing	bear	VERB
fnp-6285	8	29	in	in	ADP
fnp-6285	8	30	mind	mind	NOUN
fnp-6285	8	31	that	that	SCONJ
fnp-6285	8	32	any	any	DET
fnp-6285	8	33	patient	patient	NOUN
fnp-6285	8	34	who	who	PRON
fnp-6285	8	35	develops	develop	VERB
fnp-6285	8	36	cognitive	cognitive	ADJ
fnp-6285	8	37	disorders	disorder	NOUN
fnp-6285	8	38	,	,	PUNCT
fnp-6285	8	39	suspected	suspect	VERB
fnp-6285	8	40	of	of	ADP
fnp-6285	8	41	suffering	suffer	VERB
fnp-6285	8	42	from	from	ADP
fnp-6285	8	43	a	a	DET
fnp-6285	8	44	neurodegenerative	neurodegenerative	ADJ
fnp-6285	8	45	disease	disease	NOUN
fnp-6285	8	46	,	,	PUNCT
fnp-6285	8	47	must	must	AUX
fnp-6285	8	48	be	be	AUX
fnp-6285	8	49	considered	consider	VERB
fnp-6285	8	50	as	as	ADP
fnp-6285	8	51	being	be	AUX
fnp-6285	8	52	at	at	ADP
fnp-6285	8	53	risk	risk	NOUN
fnp-6285	8	54	of	of	ADP
fnp-6285	8	55	prion	prion	NOUN
fnp-6285	8	56	disease	disease	NOUN
fnp-6285	8	57	.	.	PUNCT
fnp-6285	8	58	  	  	SPACE
fnp-6285	9	1	free	free	ADJ
fnp-6285	9	2	neuropathol	neuropathol	NOUN
fnp-6285	9	3	6:2:3	6:2:3	NUM
fnp-6285	9	4	neuropathological	neuropathological	ADJ
fnp-6285	9	5	analysis	analysis	NOUN
fnp-6285	9	6	of	of	ADP
fnp-6285	9	7	an	an	DET
fnp-6285	9	8	als	als	NOUN
fnp-6285	9	9	patient	patient	NOUN
fnp-6285	9	10	carrying	carry	VERB
fnp-6285	9	11	a	a	DET
fnp-6285	9	12	sod1	sod1	ADJ
fnp-6285	9	13	missense	missense	NOUN
fnp-6285	9	14	mutation	mutation	NOUN
fnp-6285	9	15	and	and	CCONJ
fnp-6285	9	16	a	a	DET
fnp-6285	9	17	c9orf72	c9orf72	PROPN
fnp-6285	9	18	repeat	repeat	NOUN
fnp-6285	9	19	expansion	expansion	NOUN
fnp-6285	9	20	miki	miki	PROPN
fnp-6285	9	21	tomoko1	tomoko1	PROPN
fnp-6285	9	22	,	,	PUNCT
fnp-6285	9	23	de	de	X
fnp-6285	9	24	bertier	bertier	NOUN
fnp-6285	9	25	sibylle2	sibylle2	PROPN
fnp-6285	9	26	,	,	PUNCT
fnp-6285	9	27	deret	deret	ADJ
fnp-6285	9	28	marion2	marion2	NOUN
fnp-6285	9	29	,	,	PUNCT
fnp-6285	9	30	amador	amador	PROPN
fnp-6285	9	31	maria	maria	PROPN
fnp-6285	9	32	-	-	PUNCT
fnp-6285	9	33	del	del	PROPN
fnp-6285	9	34	-	-	PUNCT
fnp-6285	9	35	mar2–4	mar2–4	NOUN
fnp-6285	9	36	,	,	PUNCT
fnp-6285	9	37	teyssou	teyssou	PROPN
fnp-6285	9	38	elisa2	elisa2	PROPN
fnp-6285	9	39	,	,	PUNCT
fnp-6285	9	40	muratet	muratet	NOUN
fnp-6285	9	41	françois2	françois2	PROPN
fnp-6285	9	42	,	,	PUNCT
fnp-6285	9	43	bohl	bohl	PROPN
fnp-6285	9	44	delphine2	delphine2	PROPN
fnp-6285	9	45	,	,	PUNCT
fnp-6285	9	46	lobsiger	lobsiger	PROPN
fnp-6285	9	47	christian2	christian2	PROPN
fnp-6285	9	48	,	,	PUNCT
fnp-6285	9	49	boillée	boillée	PROPN
fnp-6285	9	50	séverine2	séverine2	PROPN
fnp-6285	9	51	,	,	PUNCT
fnp-6285	9	52	salachas	salachas	PROPN
fnp-6285	9	53	françois2–4	françois2–4	PROPN
fnp-6285	9	54	,	,	PUNCT
fnp-6285	9	55	millecamps	millecamp	NOUN
fnp-6285	9	56	stéphanie2	stéphanie2	ADV
fnp-6285	9	57	,	,	PUNCT
fnp-6285	9	58	seilhean	seilhean	VERB
fnp-6285	9	59	danielle1,2,4	danielle1,2,4	PROPN
fnp-6285	9	60	department	department	PROPN
fnp-6285	9	61	of	of	ADP
fnp-6285	9	62	neuropathology	neuropathology	NOUN
fnp-6285	9	63	,	,	PUNCT
fnp-6285	9	64	pitié	pitié	NOUN
fnp-6285	9	65	-	-	PUNCT
fnp-6285	9	66	salpêtrière	salpêtrière	NOUN
fnp-6285	9	67	hospital	hospital	NOUN
fnp-6285	9	68	,	,	PUNCT
fnp-6285	9	69	assistance	assistance	NOUN
fnp-6285	9	70	publique	publique	PROPN
fnp-6285	9	71	hôpitaux	hôpitaux	PROPN
fnp-6285	9	72	de	de	X
fnp-6285	9	73	paris	paris	PROPN
fnp-6285	9	74	(	(	PUNCT
fnp-6285	9	75	aphp	aphp	PROPN
fnp-6285	9	76	)	)	PUNCT
fnp-6285	9	77	,	,	PUNCT
fnp-6285	9	78	sorbonne	sorbonne	PROPN
fnp-6285	9	79	university	university	PROPN
fnp-6285	9	80	,	,	PUNCT
fnp-6285	9	81	paris	paris	PROPN
fnp-6285	9	82	,	,	PUNCT
fnp-6285	9	83	france	france	PROPN
fnp-6285	9	84	institut	institut	PROPN
fnp-6285	9	85	du	du	PROPN
fnp-6285	9	86	cerveau	cerveau	PROPN
fnp-6285	9	87	‐	‐	PROPN
fnp-6285	9	88	paris	paris	PROPN
fnp-6285	9	89	brain	brain	PROPN
fnp-6285	9	90	institute	institute	PROPN
fnp-6285	9	91	‐	‐	PROPN
fnp-6285	9	92	icm	icm	PROPN
fnp-6285	9	93	,	,	PUNCT
fnp-6285	9	94	inserm	inserm	NOUN
fnp-6285	9	95	,	,	PUNCT
fnp-6285	9	96	cnrs	cnrs	NOUN
fnp-6285	9	97	,	,	PUNCT
fnp-6285	9	98	aphp	aphp	ADJ
fnp-6285	9	99	,	,	PUNCT
fnp-6285	9	100	sorbonne	sorbonne	PROPN
fnp-6285	9	101	university	university	PROPN
fnp-6285	9	102	,	,	PUNCT
fnp-6285	9	103	pitié	pitié	PROPN
fnp-6285	9	104	salpêtrière	salpêtrière	PROPN
fnp-6285	9	105	hospital	hospital	PROPN
fnp-6285	9	106	,	,	PUNCT
fnp-6285	9	107	paris	paris	PROPN
fnp-6285	9	108	,	,	PUNCT
fnp-6285	9	109	france	france	PROPN
fnp-6285	9	110	department	department	PROPN
fnp-6285	9	111	of	of	ADP
fnp-6285	9	112	neurology	neurology	NOUN
fnp-6285	9	113	,	,	PUNCT
fnp-6285	9	114	centre	centre	NOUN
fnp-6285	9	115	de	de	X
fnp-6285	9	116	référence	référence	PROPN
fnp-6285	9	117	sla	sla	PROPN
fnp-6285	9	118	ile	ile	PROPN
fnp-6285	9	119	de	de	PROPN
fnp-6285	9	120	france	france	PROPN
fnp-6285	9	121	,	,	PUNCT
fnp-6285	9	122	pitié	pitié	NOUN
fnp-6285	9	123	-	-	PUNCT
fnp-6285	9	124	salpêtrière	salpêtrière	NOUN
fnp-6285	9	125	hospital	hospital	NOUN
fnp-6285	9	126	,	,	PUNCT
fnp-6285	9	127	aphp	aphp	ADJ
fnp-6285	9	128	,	,	PUNCT
fnp-6285	9	129	paris	paris	PROPN
fnp-6285	9	130	,	,	PUNCT
fnp-6285	9	131	france	france	PROPN
fnp-6285	9	132	dmu	dmu	PROPN
fnp-6285	9	133	de	de	X
fnp-6285	9	134	neurosciences	neurosciences	PROPN
fnp-6285	9	135	,	,	PUNCT
fnp-6285	9	136	paris	paris	PROPN
fnp-6285	9	137	,	,	PUNCT
fnp-6285	9	138	france	france	PROPN
fnp-6285	9	139	mutations	mutation	NOUN
fnp-6285	9	140	in	in	ADP
fnp-6285	9	141	the	the	DET
fnp-6285	9	142	sod1	sod1	ADJ
fnp-6285	9	143	and	and	CCONJ
fnp-6285	9	144	c9orf72	c9orf72	ADJ
fnp-6285	9	145	genes	gene	NOUN
fnp-6285	9	146	are	be	AUX
fnp-6285	9	147	responsible	responsible	ADJ
fnp-6285	9	148	for	for	ADP
fnp-6285	9	149	around	around	ADV
fnp-6285	9	150	10	10	NUM
fnp-6285	9	151	%	%	NOUN
fnp-6285	9	152	of	of	ADP
fnp-6285	9	153	apparently	apparently	ADV
fnp-6285	9	154	sporadic	sporadic	ADJ
fnp-6285	9	155	cases	case	NOUN
fnp-6285	9	156	of	of	ADP
fnp-6285	9	157	amyotrophic	amyotrophic	ADJ
fnp-6285	9	158	lateral	lateral	ADJ
fnp-6285	9	159	sclerosis	sclerosis	NOUN
fnp-6285	9	160	(	(	PUNCT
fnp-6285	9	161	als	als	NOUN
fnp-6285	9	162	)	)	PUNCT
fnp-6285	9	163	.	.	PUNCT
fnp-6285	10	1	we	we	PRON
fnp-6285	10	2	report	report	VERB
fnp-6285	10	3	the	the	DET
fnp-6285	10	4	case	case	NOUN
fnp-6285	10	5	of	of	ADP
fnp-6285	10	6	a-63	a-63	NOUN
fnp-6285	10	7	-	-	PUNCT
fnp-6285	10	8	year	year	NOUN
fnp-6285	10	9	-	-	PUNCT
fnp-6285	10	10	old	old	ADJ
fnp-6285	10	11	man	man	NOUN
fnp-6285	10	12	,	,	PUNCT
fnp-6285	10	13	with	with	ADP
fnp-6285	10	14	no	no	DET
fnp-6285	10	15	family	family	NOUN
fnp-6285	10	16	history	history	NOUN
fnp-6285	10	17	of	of	ADP
fnp-6285	10	18	als	al	NOUN
fnp-6285	10	19	,	,	PUNCT
fnp-6285	10	20	carrying	carry	VERB
fnp-6285	10	21	both	both	CCONJ
fnp-6285	10	22	a	a	DET
fnp-6285	10	23	p.thr55ile	p.thr55ile	NOUN
fnp-6285	10	24	mutation	mutation	NOUN
fnp-6285	10	25	in	in	ADP
fnp-6285	10	26	the	the	DET
fnp-6285	10	27	sod1	sod1	ADJ
fnp-6285	10	28	gene	gene	NOUN
fnp-6285	10	29	and	and	CCONJ
fnp-6285	10	30	a	a	DET
fnp-6285	10	31	c9orf72	c9orf72	PROPN
fnp-6285	10	32	repeat	repeat	NOUN
fnp-6285	10	33	expansion	expansion	NOUN
fnp-6285	10	34	.	.	PUNCT
fnp-6285	11	1	he	he	PRON
fnp-6285	11	2	died	die	VERB
fnp-6285	11	3	15	15	NUM
fnp-6285	11	4	months	month	NOUN
fnp-6285	11	5	after	after	ADP
fnp-6285	11	6	developing	develop	VERB
fnp-6285	11	7	gait	gait	NOUN
fnp-6285	11	8	disturbances	disturbance	NOUN
fnp-6285	11	9	.	.	PUNCT
fnp-6285	12	1	post	post	ADJ
fnp-6285	12	2	-	-	ADJ
fnp-6285	12	3	mortem	mortem	ADJ
fnp-6285	12	4	examination	examination	NOUN
fnp-6285	12	5	confirmed	confirm	VERB
fnp-6285	12	6	typical	typical	ADJ
fnp-6285	12	7	features	feature	NOUN
fnp-6285	12	8	of	of	ADP
fnp-6285	12	9	als	al	NOUN
fnp-6285	12	10	,	,	PUNCT
fnp-6285	12	11	including	include	VERB
fnp-6285	12	12	severe	severe	ADJ
fnp-6285	12	13	loss	loss	NOUN
fnp-6285	12	14	of	of	ADP
fnp-6285	12	15	spinal	spinal	NOUN
fnp-6285	12	16	and	and	CCONJ
fnp-6285	12	17	medullar	medullar	ADJ
fnp-6285	12	18	motor	motor	NOUN
fnp-6285	12	19	neurons	neuron	NOUN
fnp-6285	12	20	.	.	PUNCT
fnp-6285	13	1	cerebral	cerebral	ADJ
fnp-6285	13	2	atrophy	atrophy	NOUN
fnp-6285	13	3	was	be	AUX
fnp-6285	13	4	mild	mild	ADJ
fnp-6285	13	5	,	,	PUNCT
fnp-6285	13	6	with	with	ADP
fnp-6285	13	7	preservation	preservation	NOUN
fnp-6285	13	8	of	of	ADP
fnp-6285	13	9	betz	betz	PROPN
fnp-6285	13	10	cells	cell	NOUN
fnp-6285	13	11	.	.	PUNCT
fnp-6285	14	1	in	in	ADP
fnp-6285	14	2	addition	addition	NOUN
fnp-6285	14	3	to	to	ADP
fnp-6285	14	4	the	the	DET
fnp-6285	14	5	widespread	widespread	ADJ
fnp-6285	14	6	tdp-43	tdp-43	NOUN
fnp-6285	14	7	-	-	PUNCT
fnp-6285	14	8	positive	positive	ADJ
fnp-6285	14	9	neuronal	neuronal	ADJ
fnp-6285	14	10	cytoplasmic	cytoplasmic	ADJ
fnp-6285	14	11	inclusions	inclusion	NOUN
fnp-6285	14	12	(	(	PUNCT
fnp-6285	14	13	nci	nci	NOUN
fnp-6285	14	14	)	)	PUNCT
fnp-6285	14	15	,	,	PUNCT
fnp-6285	14	16	p62	p62	NOUN
fnp-6285	14	17	-	-	PUNCT
fnp-6285	14	18	positive	positive	ADJ
fnp-6285	14	19	tdp-43	tdp-43	NOUN
fnp-6285	14	20	-	-	PUNCT
fnp-6285	14	21	negative	negative	ADJ
fnp-6285	14	22	numerous	numerous	ADJ
fnp-6285	14	23	nci	nci	PROPN
fnp-6285	14	24	were	be	AUX
fnp-6285	14	25	found	find	VERB
fnp-6285	14	26	in	in	ADP
fnp-6285	14	27	the	the	DET
fnp-6285	14	28	cerebellar	cerebellar	ADJ
fnp-6285	14	29	granule	granule	NOUN
fnp-6285	14	30	cells	cell	NOUN
fnp-6285	14	31	.	.	PUNCT
fnp-6285	15	1	abundant	abundant	ADJ
fnp-6285	15	2	poly	poly	ADJ
fnp-6285	15	3	-	-	PUNCT
fnp-6285	15	4	ga	ga	NOUN
fnp-6285	15	5	-	-	PUNCT
fnp-6285	15	6	positive	positive	ADJ
fnp-6285	15	7	inclusions	inclusion	NOUN
fnp-6285	15	8	were	be	AUX
fnp-6285	15	9	observed	observe	VERB
fnp-6285	15	10	in	in	ADP
fnp-6285	15	11	the	the	DET
fnp-6285	15	12	cerebellum	cerebellum	NOUN
fnp-6285	15	13	,	,	PUNCT
fnp-6285	15	14	neocortex	neocortex	NOUN
fnp-6285	15	15	and	and	CCONJ
fnp-6285	15	16	hippocampus	hippocampus	NOUN
fnp-6285	15	17	.	.	PUNCT
fnp-6285	16	1	this	this	DET
fnp-6285	16	2	neuropathology	neuropathology	NOUN
fnp-6285	16	3	was	be	AUX
fnp-6285	16	4	typical	typical	ADJ
fnp-6285	16	5	of	of	ADP
fnp-6285	16	6	c9orf72	c9orf72	PROPN
fnp-6285	16	7	repeat	repeat	NOUN
fnp-6285	16	8	expansion	expansion	NOUN
fnp-6285	16	9	.	.	PUNCT
fnp-6285	17	1	sod1	sod1	PROPN
fnp-6285	17	2	immunochemistry	immunochemistry	PROPN
fnp-6285	17	3	showed	show	VERB
fnp-6285	17	4	axonal	axonal	ADJ
fnp-6285	17	5	-	-	PUNCT
fnp-6285	17	6	sprouting	sprouting	NOUN
fnp-6285	17	7	but	but	CCONJ
fnp-6285	17	8	no	no	DET
fnp-6285	17	9	nci	nci	NOUN
fnp-6285	17	10	in	in	ADP
fnp-6285	17	11	motor	motor	NOUN
fnp-6285	17	12	neurons	neuron	NOUN
fnp-6285	17	13	.	.	PUNCT
fnp-6285	18	1	gene	gene	NOUN
fnp-6285	18	2	therapy	therapy	NOUN
fnp-6285	18	3	targeting	target	VERB
fnp-6285	18	4	sod1	sod1	NOUN
fnp-6285	18	5	may	may	AUX
fnp-6285	18	6	not	not	PART
fnp-6285	18	7	be	be	AUX
fnp-6285	18	8	beneficial	beneficial	ADJ
fnp-6285	18	9	to	to	ADP
fnp-6285	18	10	such	such	ADJ
fnp-6285	18	11	sod1	sod1	ADJ
fnp-6285	18	12	patients	patient	NOUN
fnp-6285	18	13	deprived	deprive	VERB
fnp-6285	18	14	of	of	ADP
fnp-6285	18	15	typical	typical	ADJ
fnp-6285	18	16	sod1	sod1	ADJ
fnp-6285	18	17	-	-	PUNCT
fnp-6285	18	18	positive	positive	ADJ
fnp-6285	18	19	nci	nci	NOUN
fnp-6285	18	20	.	.	PUNCT
fnp-6285	18	21	  	  	SPACE
fnp-6285	18	22	free	free	ADJ
fnp-6285	18	23	neuropathol	neuropathol	NOUN
fnp-6285	18	24	6:2:4	6:2:4	NUM
fnp-6285	18	25	polyradiculoneuritis	polyradiculoneuritis	PROPN
fnp-6285	18	26	with	with	ADP
fnp-6285	18	27	central	central	ADJ
fnp-6285	18	28	nervous	nervous	ADJ
fnp-6285	18	29	system	system	NOUN
fnp-6285	18	30	involvement	involvement	NOUN
fnp-6285	18	31	:	:	PUNCT
fnp-6285	18	32	contribution	contribution	NOUN
fnp-6285	18	33	of	of	ADP
fnp-6285	18	34	unbiased	unbiased	ADJ
fnp-6285	18	35	metagenomics	metagenomic	NOUN
fnp-6285	18	36	to	to	ADP
fnp-6285	18	37	the	the	DET
fnp-6285	18	38	diagnosis	diagnosis	NOUN
fnp-6285	18	39	boluda	boluda	NOUN
fnp-6285	18	40	s1	s1	PROPN
fnp-6285	18	41	,	,	PUNCT
fnp-6285	18	42	plu	plu	PROPN
fnp-6285	18	43	i1	i1	PROPN
fnp-6285	18	44	,	,	PUNCT
fnp-6285	18	45	miki	miki	PROPN
fnp-6285	18	46	t1	t1	PROPN
fnp-6285	18	47	,	,	PUNCT
fnp-6285	18	48	megarbane	megarbane	NOUN
fnp-6285	18	49	b2	b2	NOUN
fnp-6285	18	50	,	,	PUNCT
fnp-6285	18	51	malissin	malissin	PROPN
fnp-6285	18	52	i2	i2	PROPN
fnp-6285	18	53	,	,	PUNCT
fnp-6285	18	54	ferroni	ferroni	ADJ
fnp-6285	18	55	a3	a3	NOUN
fnp-6285	18	56	,	,	PUNCT
fnp-6285	18	57	jamet	jamet	NOUN
fnp-6285	18	58	a3	a3	NOUN
fnp-6285	18	59	,	,	PUNCT
fnp-6285	18	60	fourgeaud	fourgeaud	PROPN
fnp-6285	18	61	j3	j3	PROPN
fnp-6285	18	62	,	,	PUNCT
fnp-6285	18	63	pérot	pérot	ADJ
fnp-6285	18	64	p4	p4	ADJ
fnp-6285	18	65	,	,	PUNCT
fnp-6285	18	66	regnault	regnault	NOUN
fnp-6285	18	67	b4	b4	NOUN
fnp-6285	18	68	,	,	PUNCT
fnp-6285	18	69	dheilly	dheilly	ADV
fnp-6285	18	70	n4	n4	PROPN
fnp-6285	18	71	,	,	PUNCT
fnp-6285	18	72	seilhean	seilhean	NOUN
fnp-6285	18	73	d1	d1	PROPN
fnp-6285	18	74	department	department	NOUN
fnp-6285	18	75	of	of	ADP
fnp-6285	18	76	neuropathology	neuropathology	NOUN
fnp-6285	18	77	,	,	PUNCT
fnp-6285	18	78	pitié	pitié	NOUN
fnp-6285	18	79	-	-	PUNCT
fnp-6285	18	80	salpêtrière	salpêtrière	NOUN
fnp-6285	18	81	hospital	hospital	NOUN
fnp-6285	18	82	,	,	PUNCT
fnp-6285	18	83	aphp	aphp	NOUN
fnp-6285	18	84	-	-	PUNCT
fnp-6285	18	85	sorbonne	sorbonne	PROPN
fnp-6285	18	86	university	university	PROPN
fnp-6285	18	87	,	,	PUNCT
fnp-6285	18	88	paris	paris	PROPN
fnp-6285	18	89	,	,	PUNCT
fnp-6285	18	90	france	france	PROPN
fnp-6285	18	91	intensive	intensive	ADJ
fnp-6285	18	92	care	care	NOUN
fnp-6285	18	93	unit	unit	NOUN
fnp-6285	18	94	,	,	PUNCT
fnp-6285	18	95	lariboisière	lariboisière	PROPN
fnp-6285	18	96	hospital	hospital	PROPN
fnp-6285	18	97	,	,	PUNCT
fnp-6285	18	98	aphpparis	aphpparis	PROPN
fnp-6285	18	99	cité	cité	PROPN
fnp-6285	18	100	university	university	PROPN
fnp-6285	18	101	,	,	PUNCT
fnp-6285	18	102	paris	paris	PROPN
fnp-6285	18	103	,	,	PUNCT
fnp-6285	18	104	france	france	PROPN
fnp-6285	18	105	department	department	PROPN
fnp-6285	18	106	of	of	ADP
fnp-6285	18	107	microbiology	microbiology	NOUN
fnp-6285	18	108	,	,	PUNCT
fnp-6285	18	109	necker	necker	NOUN
fnp-6285	18	110	hospital	hospital	NOUN
fnp-6285	18	111	,	,	PUNCT
fnp-6285	18	112	aphp	aphp	VERB
fnp-6285	18	113	-	-	PUNCT
fnp-6285	18	114	paris	paris	PROPN
fnp-6285	18	115	cité	cité	PROPN
fnp-6285	18	116	university	university	PROPN
fnp-6285	18	117	,	,	PUNCT
fnp-6285	18	118	paris	paris	PROPN
fnp-6285	18	119	,	,	PUNCT
fnp-6285	18	120	france	france	PROPN
fnp-6285	18	121	pathogen	pathogen	PROPN
fnp-6285	18	122	discovery	discovery	PROPN
fnp-6285	18	123	,	,	PUNCT
fnp-6285	18	124	pasteur	pasteur	PROPN
fnp-6285	18	125	institute	institute	PROPN
fnp-6285	18	126	,	,	PUNCT
fnp-6285	18	127	paris	paris	PROPN
fnp-6285	18	128	,	,	PUNCT
fnp-6285	18	129	france	france	PROPN
fnp-6285	18	130	a	a	DET
fnp-6285	18	131	69	69	NUM
fnp-6285	18	132	-	-	PUNCT
fnp-6285	18	133	year	year	NOUN
fnp-6285	18	134	-	-	PUNCT
fnp-6285	18	135	old	old	ADJ
fnp-6285	18	136	male	male	NOUN
fnp-6285	18	137	died	die	VERB
fnp-6285	18	138	of	of	ADP
fnp-6285	18	139	rapidly	rapidly	ADV
fnp-6285	18	140	progressing	progress	VERB
fnp-6285	18	141	polyradiculoneuritis	polyradiculoneuritis	NOUN
fnp-6285	18	142	involving	involve	VERB
fnp-6285	18	143	the	the	DET
fnp-6285	18	144	central	central	ADJ
fnp-6285	18	145	nervous	nervous	ADJ
fnp-6285	18	146	system	system	NOUN
fnp-6285	18	147	.	.	PUNCT
fnp-6285	19	1	symptoms	symptom	NOUN
fnp-6285	19	2	had	have	AUX
fnp-6285	19	3	begun	begin	VERB
fnp-6285	19	4	three	three	NUM
fnp-6285	19	5	weeks	week	NOUN
fnp-6285	19	6	earlier	early	ADV
fnp-6285	19	7	,	,	PUNCT
fnp-6285	19	8	with	with	ADP
fnp-6285	19	9	asthenia	asthenia	PROPN
fnp-6285	19	10	,	,	PUNCT
fnp-6285	19	11	diarrhea	diarrhea	NOUN
fnp-6285	19	12	and	and	CCONJ
fnp-6285	19	13	weight	weight	NOUN
fnp-6285	19	14	loss	loss	NOUN
fnp-6285	19	15	.	.	PUNCT
fnp-6285	20	1	post	post	NOUN
fnp-6285	20	2	mortem	mortem	PROPN
fnp-6285	20	3	examination	examination	NOUN
fnp-6285	20	4	revealed	reveal	VERB
fnp-6285	20	5	cerebral	cerebral	ADJ
fnp-6285	20	6	edema	edema	NOUN
fnp-6285	20	7	,	,	PUNCT
fnp-6285	20	8	soft	soft	ADJ
fnp-6285	20	9	consistency	consistency	NOUN
fnp-6285	20	10	of	of	ADP
fnp-6285	20	11	the	the	DET
fnp-6285	20	12	cerebellum	cerebellum	NOUN
fnp-6285	20	13	,	,	PUNCT
fnp-6285	20	14	necrosis	necrosis	NOUN
fnp-6285	20	15	of	of	ADP
fnp-6285	20	16	the	the	DET
fnp-6285	20	17	midbrain	midbrain	NOUN
fnp-6285	20	18	and	and	CCONJ
fnp-6285	20	19	atrophy	atrophy	NOUN
fnp-6285	20	20	of	of	ADP
fnp-6285	20	21	the	the	DET
fnp-6285	20	22	gray	gray	ADJ
fnp-6285	20	23	matter	matter	NOUN
fnp-6285	20	24	of	of	ADP
fnp-6285	20	25	the	the	DET
fnp-6285	20	26	spinal	spinal	ADJ
fnp-6285	20	27	cord	cord	NOUN
fnp-6285	20	28	.	.	PUNCT
fnp-6285	21	1	microscopic	microscopic	ADJ
fnp-6285	21	2	evaluation	evaluation	NOUN
fnp-6285	21	3	revealed	reveal	VERB
fnp-6285	21	4	necrosis	necrosis	NOUN
fnp-6285	21	5	in	in	ADP
fnp-6285	21	6	the	the	DET
fnp-6285	21	7	anterior	anterior	ADJ
fnp-6285	21	8	horns	horn	NOUN
fnp-6285	21	9	,	,	PUNCT
fnp-6285	21	10	the	the	DET
fnp-6285	21	11	cerebellum	cerebellum	NOUN
fnp-6285	21	12	,	,	PUNCT
fnp-6285	21	13	brainstem	brainstem	NOUN
fnp-6285	21	14	and	and	CCONJ
fnp-6285	21	15	temporal	temporal	ADJ
fnp-6285	21	16	lobe	lobe	NOUN
fnp-6285	21	17	,	,	PUNCT
fnp-6285	21	18	associated	associate	VERB
fnp-6285	21	19	with	with	ADP
fnp-6285	21	20	severe	severe	ADJ
fnp-6285	21	21	neuronal	neuronal	ADJ
fnp-6285	21	22	loss	loss	NOUN
fnp-6285	21	23	.	.	PUNCT
fnp-6285	22	1	in	in	ADP
fnp-6285	22	2	the	the	DET
fnp-6285	22	3	cerebellum	cerebellum	NOUN
fnp-6285	22	4	,	,	PUNCT
fnp-6285	22	5	marked	mark	VERB
fnp-6285	22	6	neuronal	neuronal	ADJ
fnp-6285	22	7	loss	loss	NOUN
fnp-6285	22	8	was	be	AUX
fnp-6285	22	9	observed	observe	VERB
fnp-6285	22	10	in	in	ADP
fnp-6285	22	11	the	the	DET
fnp-6285	22	12	purkinje	purkinje	PROPN
fnp-6285	22	13	cell	cell	NOUN
fnp-6285	22	14	layer	layer	NOUN
fnp-6285	22	15	and	and	CCONJ
fnp-6285	22	16	in	in	ADP
fnp-6285	22	17	the	the	DET
fnp-6285	22	18	dentate	dentate	ADJ
fnp-6285	22	19	nucleus	nucleus	NOUN
fnp-6285	22	20	.	.	PUNCT
fnp-6285	23	1	microglial	microglial	ADJ
fnp-6285	23	2	activation	activation	NOUN
fnp-6285	23	3	associated	associate	VERB
fnp-6285	23	4	with	with	ADP
fnp-6285	23	5	t	t	NOUN
fnp-6285	23	6	-	-	PUNCT
fnp-6285	23	7	lymphocyte	lymphocyte	NOUN
fnp-6285	23	8	(	(	PUNCT
fnp-6285	23	9	cd3	cd3	VERB
fnp-6285	23	10	+	+	NOUN
fnp-6285	23	11	)	)	PUNCT
fnp-6285	23	12	infiltration	infiltration	NOUN
fnp-6285	23	13	with	with	ADP
fnp-6285	23	14	foci	focus	NOUN
fnp-6285	23	15	of	of	ADP
fnp-6285	23	16	neuronophagy	neuronophagy	ADJ
fnp-6285	23	17	and	and	CCONJ
fnp-6285	23	18	microglial	microglial	ADJ
fnp-6285	23	19	nodules	nodule	NOUN
fnp-6285	23	20	were	be	AUX
fnp-6285	23	21	observed	observe	VERB
fnp-6285	23	22	in	in	ADP
fnp-6285	23	23	the	the	DET
fnp-6285	23	24	most	most	ADV
fnp-6285	23	25	affected	affected	ADJ
fnp-6285	23	26	regions	region	NOUN
fnp-6285	23	27	.	.	PUNCT
fnp-6285	24	1	in	in	ADP
fnp-6285	24	2	peripheral	peripheral	ADJ
fnp-6285	24	3	nerves	nerve	NOUN
fnp-6285	24	4	,	,	PUNCT
fnp-6285	24	5	perivascular	perivascular	ADJ
fnp-6285	24	6	inflammatory	inflammatory	ADJ
fnp-6285	24	7	infiltrates	infiltrate	NOUN
fnp-6285	24	8	were	be	AUX
fnp-6285	24	9	seen	see	VERB
fnp-6285	24	10	in	in	ADP
fnp-6285	24	11	the	the	DET
fnp-6285	24	12	endoneurium	endoneurium	NOUN
fnp-6285	24	13	and	and	CCONJ
fnp-6285	24	14	perineurium	perineurium	NOUN
fnp-6285	24	15	.	.	PUNCT
fnp-6285	25	1	no	no	DET
fnp-6285	25	2	cytopathogenic	cytopathogenic	ADJ
fnp-6285	25	3	effects	effect	NOUN
fnp-6285	25	4	were	be	AUX
fnp-6285	25	5	observed	observe	VERB
fnp-6285	25	6	.	.	PUNCT
fnp-6285	26	1	anti	anti	ADJ
fnp-6285	26	2	-	-	ADJ
fnp-6285	26	3	rabies	rabie	NOUN
fnp-6285	26	4	antibodies	antibody	NOUN
fnp-6285	26	5	were	be	AUX
fnp-6285	26	6	negative	negative	ADJ
fnp-6285	26	7	.	.	PUNCT
fnp-6285	27	1	unbiased	unbiased	ADJ
fnp-6285	27	2	metagenomic	metagenomic	ADJ
fnp-6285	27	3	analysis	analysis	NOUN
fnp-6285	27	4	revealed	reveal	VERB
fnp-6285	27	5	the	the	DET
fnp-6285	27	6	presence	presence	NOUN
fnp-6285	27	7	of	of	ADP
fnp-6285	27	8	a	a	DET
fnp-6285	27	9	virus	virus	NOUN
fnp-6285	27	10	previously	previously	ADV
fnp-6285	27	11	unknown	unknown	ADJ
fnp-6285	27	12	in	in	ADP
fnp-6285	27	13	human	human	ADJ
fnp-6285	27	14	encephalitis	encephalitis	NOUN
fnp-6285	27	15	.	.	PUNCT
fnp-6285	27	16	  	  	SPACE
fnp-6285	28	1	free	free	ADJ
fnp-6285	28	2	neuropathol	neuropathol	NOUN
fnp-6285	28	3	6:2:5	6:2:5	NUM
fnp-6285	28	4	cytoskeleton	cytoskeleton	PROPN
fnp-6285	28	5	perturbation	perturbation	NOUN
fnp-6285	28	6	in	in	ADP
fnp-6285	28	7	a	a	DET
fnp-6285	28	8	large	large	ADJ
fnp-6285	28	9	spastic	spastic	ADJ
fnp-6285	28	10	ataxia	ataxia	NOUN
fnp-6285	28	11	family	family	NOUN
fnp-6285	28	12	jean	jean	PROPN
fnp-6285	28	13	-	-	PUNCT
fnp-6285	28	14	loup	loup	PROPN
fnp-6285	28	15	méreaux1	méreaux1	PROPN
fnp-6285	28	16	,	,	PUNCT
fnp-6285	28	17	*	*	PUNCT
fnp-6285	28	18	,	,	PUNCT
fnp-6285	28	19	mariacristina	mariacristina	NOUN
fnp-6285	28	20	capizzi1	capizzi1	NOUN
fnp-6285	28	21	,	,	PUNCT
fnp-6285	28	22	*	*	PROPN
fnp-6285	28	23	,	,	PUNCT
fnp-6285	28	24	marie	marie	PROPN
fnp-6285	28	25	coutelier1	coutelier1	PROPN
fnp-6285	28	26	,	,	PUNCT
fnp-6285	28	27	claire	claire	NOUN
fnp-6285	28	28	-	-	PUNCT
fnp-6285	28	29	sophie	sophie	PROPN
fnp-6285	28	30	davoine1	davoine1	PROPN
fnp-6285	28	31	,	,	PUNCT
fnp-6285	28	32	susana	susana	PROPN
fnp-6285	28	33	boluda1,2	boluda1,2	PROPN
fnp-6285	28	34	,	,	PUNCT
fnp-6285	28	35	léna	léna	VERB
fnp-6285	28	36	guillot	guillot	NOUN
fnp-6285	28	37	-	-	PUNCT
fnp-6285	28	38	noël1	noël1	NOUN
fnp-6285	28	39	,	,	PUNCT
fnp-6285	28	40	sabrina	sabrina	PROPN
fnp-6285	28	41	leclere	leclere	ADV
fnp-6285	28	42	-	-	PUNCT
fnp-6285	28	43	turbant1	turbant1	PROPN
fnp-6285	28	44	,	,	PUNCT
fnp-6285	28	45	franck	franck	PROPN
fnp-6285	28	46	letournel3	letournel3	PROPN
fnp-6285	28	47	,	,	PUNCT
fnp-6285	28	48	philippe	philippe	PROPN
fnp-6285	28	49	codron3	codron3	PROPN
fnp-6285	28	50	,	,	PUNCT
fnp-6285	28	51	badreddine	badreddine	PROPN
fnp-6285	28	52	mohand	mohand	NOUN
fnp-6285	28	53	oumoussa4	oumoussa4	NOUN
fnp-6285	28	54	,	,	PUNCT
fnp-6285	28	55	hélène	hélène	ADJ
fnp-6285	28	56	madry4	madry4	PROPN
fnp-6285	28	57	,	,	PUNCT
fnp-6285	28	58	ludmila	ludmila	PROPN
fnp-6285	28	59	jornea1	jornea1	PROPN
fnp-6285	28	60	,	,	PUNCT
fnp-6285	28	61	giovanni	giovanni	PROPN
fnp-6285	28	62	stevanin5	stevanin5	PROPN
fnp-6285	28	63	,	,	PUNCT
fnp-6285	28	64	marie	marie	PROPN
fnp-6285	28	65	-	-	PUNCT
fnp-6285	28	66	lorraine	lorraine	PROPN
fnp-6285	28	67	monin6	monin6	PROPN
fnp-6285	28	68	,	,	PUNCT
fnp-6285	28	69	sandrine	sandrine	PROPN
fnp-6285	28	70	humbert1	humbert1	PROPN
fnp-6285	28	71	,	,	PUNCT
fnp-6285	28	72	alexis	alexis	PROPN
fnp-6285	28	73	brice1	brice1	PROPN
fnp-6285	28	74	,	,	PUNCT
fnp-6285	28	75	danielle	danielle	PROPN
fnp-6285	28	76	seilhean1,2	seilhean1,2	PROPN
fnp-6285	28	77	,	,	PUNCT
fnp-6285	28	78	alexandra	alexandra	PROPN
fnp-6285	28	79	durr1,4	durr1,4	PROPN
fnp-6285	28	80	sorbonne	sorbonne	PROPN
fnp-6285	28	81	université	université	PROPN
fnp-6285	28	82	,	,	PUNCT
fnp-6285	28	83	institut	institut	PROPN
fnp-6285	28	84	du	du	PROPN
fnp-6285	28	85	cerveau	cerveau	PROPN
fnp-6285	28	86	paris	paris	PROPN
fnp-6285	28	87	brain	brain	PROPN
fnp-6285	28	88	instituteicm	instituteicm	PROPN
fnp-6285	28	89	,	,	PUNCT
fnp-6285	28	90	inserm	inserm	NOUN
fnp-6285	28	91	,	,	PUNCT
fnp-6285	28	92	cnrs	cnrs	NOUN
fnp-6285	28	93	,	,	PUNCT
fnp-6285	28	94	aphp	aphp	ADJ
fnp-6285	28	95	,	,	PUNCT
fnp-6285	28	96	university	university	NOUN
fnp-6285	28	97	hospital	hospital	NOUN
fnp-6285	28	98	pitié	pitié	PROPN
fnp-6285	28	99	-	-	PUNCT
fnp-6285	28	100	salpêtrière	salpêtrière	PROPN
fnp-6285	28	101	,	,	PUNCT
fnp-6285	28	102	paris	paris	PROPN
fnp-6285	28	103	,	,	PUNCT
fnp-6285	28	104	france	france	PROPN
fnp-6285	28	105	department	department	PROPN
fnp-6285	28	106	of	of	ADP
fnp-6285	28	107	neuropathology	neuropathology	NOUN
fnp-6285	28	108	,	,	PUNCT
fnp-6285	28	109	aphp	aphp	PROPN
fnp-6285	28	110	.	.	PUNCT
fnp-6285	29	1	sorbonne	sorbonne	PROPN
fnp-6285	29	2	university	university	PROPN
fnp-6285	29	3	,	,	PUNCT
fnp-6285	29	4	paris	paris	PROPN
fnp-6285	29	5	,	,	PUNCT
fnp-6285	29	6	france	france	PROPN
fnp-6285	29	7	centre	centre	PROPN
fnp-6285	29	8	de	de	X
fnp-6285	29	9	référence	référence	PROPN
fnp-6285	29	10	sur	sur	PROPN
fnp-6285	29	11	la	la	PROPN
fnp-6285	29	12	sla	sla	PROPN
fnp-6285	29	13	d'angers	d'anger	NOUN
fnp-6285	29	14	,	,	PUNCT
fnp-6285	29	15	centre	centre	NOUN
fnp-6285	29	16	hospitalier	hospitalier	ADJ
fnp-6285	29	17	universitaire	universitaire	ADJ
fnp-6285	29	18	d'angers	d'anger	NOUN
fnp-6285	29	19	,	,	PUNCT
fnp-6285	29	20	angers	anger	NOUN
fnp-6285	29	21	,	,	PUNCT
fnp-6285	29	22	france	france	PROPN
fnp-6285	29	23	;	;	PUNCT
fnp-6285	29	24	laboratoire	laboratoire	PROPN
fnp-6285	29	25	de	de	PROPN
fnp-6285	29	26	neurobiologie	neurobiologie	PROPN
fnp-6285	29	27	et	et	PROPN
fnp-6285	29	28	neuropathologie	neuropathologie	NOUN
fnp-6285	29	29	,	,	PUNCT
fnp-6285	29	30	centre	centre	NOUN
fnp-6285	29	31	hospitalier	hospitalier	ADJ
fnp-6285	29	32	universitaire	universitaire	ADJ
fnp-6285	29	33	d'angers	d'anger	NOUN
fnp-6285	29	34	,	,	PUNCT
fnp-6285	29	35	angers	anger	NOUN
fnp-6285	29	36	,	,	PUNCT
fnp-6285	29	37	france	france	PROPN
fnp-6285	29	38	;	;	PUNCT
fnp-6285	29	39	university	university	NOUN
fnp-6285	29	40	of	of	ADP
fnp-6285	29	41	angers	anger	NOUN
fnp-6285	29	42	,	,	PUNCT
fnp-6285	29	43	inserm	inserm	NOUN
fnp-6285	29	44	,	,	PUNCT
fnp-6285	29	45	cnrs	cnrs	NOUN
fnp-6285	29	46	,	,	PUNCT
fnp-6285	29	47	mitovasc	mitovasc	PROPN
fnp-6285	29	48	,	,	PUNCT
fnp-6285	29	49	sfr	sfr	ADJ
fnp-6285	29	50	icat	icat	NOUN
fnp-6285	29	51	,	,	PUNCT
fnp-6285	29	52	angers	anger	VERB
fnp-6285	29	53	,	,	PUNCT
fnp-6285	29	54	france	france	PROPN
fnp-6285	29	55	sorbonne	sorbonne	PROPN
fnp-6285	29	56	université	université	PROPN
fnp-6285	29	57	,	,	PUNCT
fnp-6285	29	58	inserm	inserm	NOUN
fnp-6285	29	59	,	,	PUNCT
fnp-6285	29	60	ums	ums	PROPN
fnp-6285	29	61	production	production	NOUN
fnp-6285	29	62	et	et	PROPN
fnp-6285	29	63	analyse	analyse	PROPN
fnp-6285	29	64	des	des	PROPN
fnp-6285	29	65	données	données	PROPN
fnp-6285	29	66	en	en	X
fnp-6285	29	67	sciences	sciences	PROPN
fnp-6285	29	68	de	de	X
fnp-6285	29	69	la	la	X
fnp-6285	29	70	vie	vie	X
fnp-6285	29	71	et	et	PROPN
fnp-6285	29	72	en	en	X
fnp-6285	29	73	santé	santé	PROPN
fnp-6285	29	74	,	,	PUNCT
fnp-6285	29	75	pass	pass	VERB
fnp-6285	29	76	,	,	PUNCT
fnp-6285	29	77	plateforme	plateforme	PROPN
fnp-6285	29	78	post	post	ADJ
fnp-6285	29	79	-	-	ADJ
fnp-6285	29	80	génomique	génomique	ADJ
fnp-6285	29	81	de	de	X
fnp-6285	29	82	la	la	X
fnp-6285	29	83	pitié	pitié	PROPN
fnp-6285	29	84	-	-	PUNCT
fnp-6285	29	85	salpêtrière	salpêtrière	PROPN
fnp-6285	29	86	,	,	PUNCT
fnp-6285	29	87	paris	paris	PROPN
fnp-6285	29	88	,	,	PUNCT
fnp-6285	29	89	france	france	PROPN
fnp-6285	29	90	bordeaux	bordeaux	PROPN
fnp-6285	29	91	university	university	PROPN
fnp-6285	29	92	(	(	PUNCT
fnp-6285	29	93	université	université	PROPN
fnp-6285	29	94	de	de	X
fnp-6285	29	95	bordeaux	bordeaux	PROPN
fnp-6285	29	96	)	)	PUNCT
fnp-6285	29	97	,	,	PUNCT
fnp-6285	29	98	equipe	equipe	ADJ
fnp-6285	29	99	«	«	PUNCT
fnp-6285	29	100	neurogénétique	neurogénétique	ADJ
fnp-6285	29	101	translationnelle	translationnelle	NOUN
fnp-6285	29	102	nrgen	nrgen	ADV
fnp-6285	29	103	»	»	ADV
fnp-6285	29	104	,	,	PUNCT
fnp-6285	29	105	incia	incia	NOUN
fnp-6285	29	106	cnrs	cnrs	NOUN
fnp-6285	29	107	umr5287	umr5287	NOUN
fnp-6285	29	108	,	,	PUNCT
fnp-6285	29	109	ephe	ephe	NOUN
fnp-6285	29	110	,	,	PUNCT
fnp-6285	29	111	33000	33000	NUM
fnp-6285	29	112	,	,	PUNCT
fnp-6285	29	113	bordeaux	bordeaux	NOUN
fnp-6285	29	114	,	,	PUNCT
fnp-6285	29	115	france	france	PROPN
fnp-6285	29	116	centre	centre	PROPN
fnp-6285	29	117	de	de	PROPN
fnp-6285	29	118	reference	reference	NOUN
fnp-6285	29	119	maladies	maladie	VERB
fnp-6285	29	120	rares	rare	NOUN
fnp-6285	29	121	«	«	PUNCT
fnp-6285	29	122	neurogénétique	neurogénétique	NOUN
fnp-6285	29	123	»	»	NOUN
fnp-6285	29	124	,	,	PUNCT
fnp-6285	29	125	service	service	PROPN
fnp-6285	29	126	de	de	X
fnp-6285	29	127	génétique	génétique	PROPN
fnp-6285	29	128	médicale	médicale	PROPN
fnp-6285	29	129	,	,	PUNCT
fnp-6285	29	130	bordeaux	bordeaux	PROPN
fnp-6285	29	131	university	university	NOUN
fnp-6285	29	132	hospital	hospital	NOUN
fnp-6285	29	133	(	(	PUNCT
fnp-6285	29	134	chu	chu	NOUN
fnp-6285	29	135	bordeaux	bordeaux	PROPN
fnp-6285	29	136	)	)	PUNCT
fnp-6285	29	137	,	,	PUNCT
fnp-6285	29	138	33000	33000	NUM
fnp-6285	29	139	,	,	PUNCT
fnp-6285	29	140	bordeaux	bordeaux	NOUN
fnp-6285	29	141	,	,	PUNCT
fnp-6285	29	142	france	france	PROPN
fnp-6285	29	143	*	*	PUNCT
fnp-6285	29	144	these	these	DET
fnp-6285	29	145	authors	author	NOUN
fnp-6285	29	146	share	share	VERB
fnp-6285	29	147	senior	senior	ADJ
fnp-6285	29	148	authorship	authorship	NOUN
fnp-6285	29	149	hereditary	hereditary	ADJ
fnp-6285	29	150	spastic	spastic	ADJ
fnp-6285	29	151	ataxias	ataxia	NOUN
fnp-6285	29	152	are	be	AUX
fnp-6285	29	153	a	a	DET
fnp-6285	29	154	clinically	clinically	ADV
fnp-6285	29	155	diverse	diverse	ADJ
fnp-6285	29	156	group	group	NOUN
fnp-6285	29	157	of	of	ADP
fnp-6285	29	158	neurodegenerative	neurodegenerative	ADJ
fnp-6285	29	159	disorders	disorder	NOUN
fnp-6285	29	160	,	,	PUNCT
fnp-6285	29	161	primarily	primarily	ADV
fnp-6285	29	162	characterized	characterize	VERB
fnp-6285	29	163	by	by	ADP
fnp-6285	29	164	spasticity	spasticity	NOUN
fnp-6285	29	165	in	in	ADP
fnp-6285	29	166	the	the	DET
fnp-6285	29	167	lower	low	ADJ
fnp-6285	29	168	limbs	limb	NOUN
fnp-6285	29	169	and	and	CCONJ
fnp-6285	29	170	generalized	generalized	ADJ
fnp-6285	29	171	ataxia	ataxia	NOUN
fnp-6285	29	172	.	.	PUNCT
fnp-6285	30	1	here	here	ADV
fnp-6285	30	2	,	,	PUNCT
fnp-6285	30	3	we	we	PRON
fnp-6285	30	4	report	report	VERB
fnp-6285	30	5	an	an	DET
fnp-6285	30	6	extensive	extensive	ADJ
fnp-6285	30	7	neuropathological	neuropathological	ADJ
fnp-6285	30	8	and	and	CCONJ
fnp-6285	30	9	functional	functional	ADJ
fnp-6285	30	10	study	study	NOUN
fnp-6285	30	11	on	on	ADP
fnp-6285	30	12	a	a	DET
fnp-6285	30	13	large	large	ADJ
fnp-6285	30	14	family	family	NOUN
fnp-6285	30	15	affected	affect	VERB
fnp-6285	30	16	by	by	ADP
fnp-6285	30	17	autosomal	autosomal	ADJ
fnp-6285	30	18	dominant	dominant	ADJ
fnp-6285	30	19	spastic	spastic	ADJ
fnp-6285	30	20	ataxia	ataxia	NOUN
fnp-6285	30	21	.	.	PUNCT
fnp-6285	31	1	the	the	DET
fnp-6285	31	2	disease	disease	NOUN
fnp-6285	31	3	manifests	manifest	VERB
fnp-6285	31	4	around	around	ADP
fnp-6285	31	5	the	the	DET
fnp-6285	31	6	age	age	NOUN
fnp-6285	31	7	of	of	ADP
fnp-6285	31	8	40	40	NUM
fnp-6285	31	9	,	,	PUNCT
fnp-6285	31	10	beginning	begin	VERB
fnp-6285	31	11	with	with	ADP
fnp-6285	31	12	intermittent	intermittent	ADJ
fnp-6285	31	13	dystonia	dystonia	NOUN
fnp-6285	31	14	in	in	ADP
fnp-6285	31	15	the	the	DET
fnp-6285	31	16	lower	low	ADJ
fnp-6285	31	17	limbs	limb	NOUN
fnp-6285	31	18	,	,	PUNCT
fnp-6285	31	19	followed	follow	VERB
fnp-6285	31	20	by	by	ADP
fnp-6285	31	21	severe	severe	ADJ
fnp-6285	31	22	,	,	PUNCT
fnp-6285	31	23	disabling	disable	VERB
fnp-6285	31	24	cerebellar	cerebellar	ADJ
fnp-6285	31	25	ataxia	ataxia	NOUN
fnp-6285	31	26	and	and	CCONJ
fnp-6285	31	27	spasticity	spasticity	NOUN
fnp-6285	31	28	.	.	PUNCT
fnp-6285	32	1	the	the	DET
fnp-6285	32	2	condition	condition	NOUN
fnp-6285	32	3	progresses	progress	VERB
fnp-6285	32	4	rapidly	rapidly	ADV
fnp-6285	32	5	,	,	PUNCT
fnp-6285	32	6	leading	lead	VERB
fnp-6285	32	7	to	to	ADP
fnp-6285	32	8	death	death	NOUN
fnp-6285	32	9	within	within	ADP
fnp-6285	32	10	15	15	NUM
fnp-6285	32	11	years	year	NOUN
fnp-6285	32	12	of	of	ADP
fnp-6285	32	13	the	the	DET
fnp-6285	32	14	onset	onset	NOUN
fnp-6285	32	15	age	age	NOUN
fnp-6285	32	16	.	.	PUNCT
fnp-6285	33	1	postmortem	postmortem	NOUN
fnp-6285	33	2	neuropathological	neuropathological	ADJ
fnp-6285	33	3	analysis	analysis	NOUN
fnp-6285	33	4	revealed	reveal	VERB
fnp-6285	33	5	purkinje	purkinje	PROPN
fnp-6285	33	6	cell	cell	NOUN
fnp-6285	33	7	loss	loss	NOUN
fnp-6285	33	8	,	,	PUNCT
fnp-6285	33	9	motor	motor	NOUN
fnp-6285	33	10	tract	tract	NOUN
fnp-6285	33	11	atrophy	atrophy	NOUN
fnp-6285	33	12	,	,	PUNCT
fnp-6285	33	13	and	and	CCONJ
fnp-6285	33	14	abnormalities	abnormality	NOUN
fnp-6285	33	15	in	in	ADP
fnp-6285	33	16	the	the	DET
fnp-6285	33	17	motile	motile	ADJ
fnp-6285	33	18	cilia	cilia	NOUN
fnp-6285	33	19	at	at	ADP
fnp-6285	33	20	the	the	DET
fnp-6285	33	21	ependymal	ependymal	ADJ
fnp-6285	33	22	border	border	NOUN
fnp-6285	33	23	.	.	PUNCT
fnp-6285	34	1	despite	despite	SCONJ
fnp-6285	34	2	these	these	DET
fnp-6285	34	3	findings	finding	NOUN
fnp-6285	34	4	,	,	PUNCT
fnp-6285	34	5	the	the	DET
fnp-6285	34	6	underlying	underlie	VERB
fnp-6285	34	7	molecular	molecular	ADJ
fnp-6285	34	8	mechanisms	mechanism	NOUN
fnp-6285	34	9	remain	remain	VERB
fnp-6285	34	10	unclear	unclear	ADJ
fnp-6285	34	11	.	.	PUNCT
fnp-6285	35	1	through	through	ADP
fnp-6285	35	2	a	a	DET
fnp-6285	35	3	combination	combination	NOUN
fnp-6285	35	4	of	of	ADP
fnp-6285	35	5	transcriptomic	transcriptomic	ADJ
fnp-6285	35	6	and	and	CCONJ
fnp-6285	35	7	cellular	cellular	ADJ
fnp-6285	35	8	analyses	analysis	NOUN
fnp-6285	35	9	,	,	PUNCT
fnp-6285	35	10	we	we	PRON
fnp-6285	35	11	identified	identify	VERB
fnp-6285	35	12	significant	significant	ADJ
fnp-6285	35	13	involvement	involvement	NOUN
fnp-6285	35	14	of	of	ADP
fnp-6285	35	15	cytoskeletal	cytoskeletal	ADJ
fnp-6285	35	16	pathways	pathway	NOUN
fnp-6285	35	17	involved	involve	VERB
fnp-6285	35	18	in	in	ADP
fnp-6285	35	19	the	the	DET
fnp-6285	35	20	organization	organization	NOUN
fnp-6285	35	21	of	of	ADP
fnp-6285	35	22	actin	actin	NOUN
fnp-6285	35	23	and	and	CCONJ
fnp-6285	35	24	microtubule	microtubule	NOUN
fnp-6285	35	25	networks	network	NOUN
fnp-6285	35	26	,	,	PUNCT
fnp-6285	35	27	which	which	PRON
fnp-6285	35	28	must	must	AUX
fnp-6285	35	29	be	be	AUX
fnp-6285	35	30	related	relate	VERB
fnp-6285	35	31	to	to	ADP
fnp-6285	35	32	the	the	DET
fnp-6285	35	33	molecular	molecular	ADJ
fnp-6285	35	34	cause	cause	NOUN
fnp-6285	35	35	of	of	ADP
fnp-6285	35	36	the	the	DET
fnp-6285	35	37	disease	disease	NOUN
fnp-6285	35	38	.	.	PUNCT
fnp-6285	35	39	  	  	SPACE
fnp-6285	36	1	free	free	ADJ
fnp-6285	36	2	neuropathol	neuropathol	NOUN
fnp-6285	36	3	6:2:6	6:2:6	NUM
fnp-6285	36	4	rna	rna	NOUN
fnp-6285	36	5	quality	quality	NOUN
fnp-6285	36	6	in	in	ADP
fnp-6285	36	7	postmortem	postmortem	NOUN
fnp-6285	36	8	brain	brain	NOUN
fnp-6285	36	9	tissue	tissue	NOUN
fnp-6285	36	10	.	.	PUNCT
fnp-6285	37	1	the	the	DET
fnp-6285	37	2	neuro	neuro	PROPN
fnp-6285	37	3	-	-	PUNCT
fnp-6285	37	4	ceb	ceb	PROPN
fnp-6285	37	5	experience	experience	NOUN
fnp-6285	37	6	.	.	PUNCT
fnp-6285	38	1	nasr	nasr	PROPN
fnp-6285	38	2	o1	o1	PROPN
fnp-6285	38	3	,	,	PUNCT
fnp-6285	38	4	leclère	leclère	NOUN
fnp-6285	38	5	s2	s2	PROPN
fnp-6285	38	6	,	,	PUNCT
fnp-6285	38	7	plu	plu	PROPN
fnp-6285	38	8	i1	i1	PROPN
fnp-6285	38	9	,	,	PUNCT
fnp-6285	38	10	maraña	maraña	NOUN
fnp-6285	38	11	s3	s3	PROPN
fnp-6285	38	12	,	,	PUNCT
fnp-6285	38	13	seilhean	seilhean	ADJ
fnp-6285	38	14	d1	d1	NOUN
fnp-6285	38	15	,	,	PUNCT
fnp-6285	38	16	boluda	boluda	NOUN
fnp-6285	38	17	s1	s1	PROPN
fnp-6285	38	18	department	department	PROPN
fnp-6285	38	19	of	of	ADP
fnp-6285	38	20	neuropathology	neuropathology	NOUN
fnp-6285	38	21	,	,	PUNCT
fnp-6285	38	22	pitié	pitié	NOUN
fnp-6285	38	23	-	-	PUNCT
fnp-6285	38	24	salpêtrière	salpêtrière	NOUN
fnp-6285	38	25	hospital	hospital	NOUN
fnp-6285	38	26	,	,	PUNCT
fnp-6285	38	27	aphp	aphp	NOUN
fnp-6285	38	28	-	-	PUNCT
fnp-6285	38	29	sorbonne	sorbonne	PROPN
fnp-6285	38	30	university	university	PROPN
fnp-6285	38	31	,	,	PUNCT
fnp-6285	38	32	paris	paris	PROPN
fnp-6285	38	33	,	,	PUNCT
fnp-6285	38	34	france	france	PROPN
fnp-6285	38	35	neuro	neuro	PROPN
fnp-6285	38	36	-	-	PUNCT
fnp-6285	38	37	ceb	ceb	PROPN
fnp-6285	38	38	brain	brain	PROPN
fnp-6285	38	39	bank	bank	PROPN
fnp-6285	38	40	,	,	PUNCT
fnp-6285	38	41	aphp	aphp	NOUN
fnp-6285	38	42	-	-	PUNCT
fnp-6285	38	43	sorbonne	sorbonne	PROPN
fnp-6285	38	44	university	university	PROPN
fnp-6285	38	45	,	,	PUNCT
fnp-6285	38	46	paris	paris	PROPN
fnp-6285	38	47	,	,	PUNCT
fnp-6285	38	48	france	france	PROPN
fnp-6285	38	49	paris	paris	PROPN
fnp-6285	38	50	brain	brain	PROPN
fnp-6285	38	51	institute	institute	PROPN
fnp-6285	38	52	,	,	PUNCT
fnp-6285	38	53	icm	icm	PROPN
fnp-6285	38	54	,	,	PUNCT
fnp-6285	38	55	cnrs	cnrs	NOUN
fnp-6285	38	56	umr7225	umr7225	ADJ
fnp-6285	38	57	–	–	PUNCT
fnp-6285	38	58	inserm	inserm	NOUN
fnp-6285	38	59	u1127	u1127	PROPN
fnp-6285	38	60	–	–	PUNCT
fnp-6285	38	61	upmc	upmc	PROPN
fnp-6285	38	62	,	,	PUNCT
fnp-6285	38	63	paris	paris	PROPN
fnp-6285	38	64	,	,	PUNCT
fnp-6285	38	65	france	france	PROPN
fnp-6285	38	66	molecular	molecular	ADJ
fnp-6285	38	67	research	research	NOUN
fnp-6285	38	68	is	be	AUX
fnp-6285	38	69	often	often	ADV
fnp-6285	38	70	carried	carry	VERB
fnp-6285	38	71	out	out	ADP
fnp-6285	38	72	on	on	ADP
fnp-6285	38	73	postmortem	postmortem	NOUN
fnp-6285	38	74	brain	brain	NOUN
fnp-6285	38	75	tissue	tissue	NOUN
fnp-6285	38	76	,	,	PUNCT
fnp-6285	38	77	whose	whose	DET
fnp-6285	38	78	usability	usability	NOUN
fnp-6285	38	79	must	must	AUX
fnp-6285	38	80	be	be	AUX
fnp-6285	38	81	guaranteed	guarantee	VERB
fnp-6285	38	82	.	.	PUNCT
fnp-6285	39	1	brain	brain	NOUN
fnp-6285	39	2	ph	ph	PROPN
fnp-6285	39	3	is	be	AUX
fnp-6285	39	4	a	a	DET
fnp-6285	39	5	good	good	ADJ
fnp-6285	39	6	indicator	indicator	NOUN
fnp-6285	39	7	of	of	ADP
fnp-6285	39	8	rna	rna	NOUN
fnp-6285	39	9	quality	quality	NOUN
fnp-6285	39	10	(	(	PUNCT
fnp-6285	39	11	rin	rin	NOUN
fnp-6285	39	12	)	)	PUNCT
fnp-6285	39	13	.	.	PUNCT
fnp-6285	40	1	however	however	ADV
fnp-6285	40	2	,	,	PUNCT
fnp-6285	40	3	the	the	DET
fnp-6285	40	4	procedure	procedure	NOUN
fnp-6285	40	5	is	be	AUX
fnp-6285	40	6	time	time	NOUN
fnp-6285	40	7	consuming	consume	VERB
fnp-6285	40	8	.	.	PUNCT
fnp-6285	41	1	ogata	ogata	PROPN
fnp-6285	41	2	et	et	PROPN
fnp-6285	41	3	al	al	PROPN
fnp-6285	41	4	(	(	PUNCT
fnp-6285	41	5	1986	1986	NUM
fnp-6285	41	6	)	)	PUNCT
fnp-6285	41	7	showed	show	VERB
fnp-6285	41	8	that	that	SCONJ
fnp-6285	41	9	the	the	DET
fnp-6285	41	10	severity	severity	NOUN
fnp-6285	41	11	of	of	ADP
fnp-6285	41	12	autolysis	autolysis	NOUN
fnp-6285	41	13	of	of	ADP
fnp-6285	41	14	the	the	DET
fnp-6285	41	15	cerebellar	cerebellar	ADJ
fnp-6285	41	16	granular	granular	ADJ
fnp-6285	41	17	layer	layer	NOUN
fnp-6285	41	18	(	(	PUNCT
fnp-6285	41	19	acgl	acgl	ADJ
fnp-6285	41	20	)	)	PUNCT
fnp-6285	41	21	correlates	correlate	VERB
fnp-6285	41	22	significantly	significantly	ADV
fnp-6285	41	23	with	with	ADP
fnp-6285	41	24	brain	brain	NOUN
fnp-6285	41	25	ph	ph	NOUN
fnp-6285	41	26	and	and	CCONJ
fnp-6285	41	27	rin1	rin1	NOUN
fnp-6285	41	28	.	.	PUNCT
fnp-6285	42	1	our	our	PRON
fnp-6285	42	2	aim	aim	NOUN
fnp-6285	42	3	was	be	AUX
fnp-6285	42	4	:	:	PUNCT
fnp-6285	42	5	a	a	X
fnp-6285	42	6	)	)	PUNCT
fnp-6285	42	7	to	to	PART
fnp-6285	42	8	evaluate	evaluate	VERB
fnp-6285	42	9	this	this	DET
fnp-6285	42	10	correlation	correlation	NOUN
fnp-6285	42	11	within	within	ADP
fnp-6285	42	12	the	the	DET
fnp-6285	42	13	neuro	neuro	PROPN
fnp-6285	42	14	-	-	PUNCT
fnp-6285	42	15	ceb	ceb	PROPN
fnp-6285	42	16	brain	brain	PROPN
fnp-6285	42	17	bank	bank	PROPN
fnp-6285	42	18	cohort	cohort	PROPN
fnp-6285	42	19	,	,	PUNCT
fnp-6285	42	20	b	b	NOUN
fnp-6285	42	21	)	)	PUNCT
fnp-6285	42	22	to	to	PART
fnp-6285	42	23	extend	extend	VERB
fnp-6285	42	24	the	the	DET
fnp-6285	42	25	study	study	NOUN
fnp-6285	42	26	to	to	PART
fnp-6285	42	27	frequently	frequently	ADV
fnp-6285	42	28	requested	request	VERB
fnp-6285	42	29	brain	brain	NOUN
fnp-6285	42	30	regions	region	NOUN
fnp-6285	42	31	other	other	ADJ
fnp-6285	42	32	than	than	ADP
fnp-6285	42	33	the	the	DET
fnp-6285	42	34	cerebellum	cerebellum	NOUN
fnp-6285	42	35	.	.	PUNCT
fnp-6285	43	1	we	we	PRON
fnp-6285	43	2	analyzed	analyze	VERB
fnp-6285	43	3	the	the	DET
fnp-6285	43	4	rin	rin	NOUN
fnp-6285	43	5	in	in	ADP
fnp-6285	43	6	six	six	NUM
fnp-6285	43	7	different	different	ADJ
fnp-6285	43	8	brain	brain	NOUN
fnp-6285	43	9	regions	region	NOUN
fnp-6285	43	10	(	(	PUNCT
fnp-6285	43	11	cerebellum	cerebellum	ADJ
fnp-6285	43	12	,	,	PUNCT
fnp-6285	43	13	frontal	frontal	ADJ
fnp-6285	43	14	cortex	cortex	NOUN
fnp-6285	43	15	,	,	PUNCT
fnp-6285	43	16	temporal	temporal	ADJ
fnp-6285	43	17	cortex	cortex	NOUN
fnp-6285	43	18	,	,	PUNCT
fnp-6285	43	19	hippocampus	hippocampus	NOUN
fnp-6285	43	20	,	,	PUNCT
fnp-6285	43	21	caudate	caudate	ADJ
fnp-6285	43	22	nucleus	nucleus	NOUN
fnp-6285	43	23	and	and	CCONJ
fnp-6285	43	24	substantia	substantia	NOUN
fnp-6285	43	25	nigra	nigra	PROPN
fnp-6285	43	26	)	)	PUNCT
fnp-6285	43	27	from	from	ADP
fnp-6285	43	28	20	20	NUM
fnp-6285	43	29	neuro	neuro	PROPN
fnp-6285	43	30	-	-	PUNCT
fnp-6285	43	31	ceb	ceb	NOUN
fnp-6285	43	32	postmortem	postmortem	NOUN
fnp-6285	43	33	cases	case	NOUN
fnp-6285	43	34	:	:	PUNCT
fnp-6285	43	35	acgl	acgl	ADJ
fnp-6285	43	36	grade	grade	NOUN
fnp-6285	43	37	0	0	NUM
fnp-6285	43	38	(	(	PUNCT
fnp-6285	43	39	n=10	n=10	NOUN
fnp-6285	43	40	)	)	PUNCT
fnp-6285	43	41	and	and	CCONJ
fnp-6285	43	42	acgl	acgl	ADJ
fnp-6285	43	43	grade	grade	NOUN
fnp-6285	43	44	4	4	NUM
fnp-6285	43	45	(	(	PUNCT
fnp-6285	43	46	n=10	n=10	NOUN
fnp-6285	43	47	)	)	PUNCT
fnp-6285	43	48	.	.	PUNCT
fnp-6285	44	1	our	our	PRON
fnp-6285	44	2	results	result	NOUN
fnp-6285	44	3	indicate	indicate	VERB
fnp-6285	44	4	:	:	PUNCT
fnp-6285	44	5	a	a	X
fnp-6285	44	6	)	)	PUNCT
fnp-6285	44	7	acgl	acgl	NOUN
fnp-6285	44	8	tend	tend	VERB
fnp-6285	44	9	to	to	PART
fnp-6285	44	10	correlate	correlate	VERB
fnp-6285	44	11	with	with	ADP
fnp-6285	44	12	the	the	DET
fnp-6285	44	13	rin	rin	NOUN
fnp-6285	44	14	in	in	ADP
fnp-6285	44	15	the	the	DET
fnp-6285	44	16	cerebellum	cerebellum	NOUN
fnp-6285	44	17	,	,	PUNCT
fnp-6285	44	18	but	but	CCONJ
fnp-6285	44	19	not	not	PART
fnp-6285	44	20	in	in	ADP
fnp-6285	44	21	the	the	DET
fnp-6285	44	22	other	other	ADJ
fnp-6285	44	23	brain	brain	NOUN
fnp-6285	44	24	regions	region	NOUN
fnp-6285	44	25	,	,	PUNCT
fnp-6285	44	26	b	b	X
fnp-6285	44	27	)	)	PUNCT
fnp-6285	44	28	there	there	PRON
fnp-6285	44	29	is	be	VERB
fnp-6285	44	30	a	a	DET
fnp-6285	44	31	different	different	ADJ
fnp-6285	44	32	susceptibility	susceptibility	NOUN
fnp-6285	44	33	to	to	PART
fnp-6285	44	34	rna	rna	VERB
fnp-6285	44	35	degradation	degradation	NOUN
fnp-6285	44	36	in	in	ADP
fnp-6285	44	37	distinct	distinct	ADJ
fnp-6285	44	38	brain	brain	NOUN
fnp-6285	44	39	regions	region	NOUN
fnp-6285	44	40	.	.	PUNCT
fnp-6285	44	41	  	  	SPACE
fnp-6285	45	1	free	free	ADJ
fnp-6285	45	2	neuropathol	neuropathol	NOUN
fnp-6285	45	3	6:2:7–8	6:2:7–8	DET
fnp-6285	45	4	ai	ai	NOUN
fnp-6285	45	5	-	-	PUNCT
fnp-6285	45	6	driven	drive	VERB
fnp-6285	45	7	digital	digital	ADJ
fnp-6285	45	8	pathology	pathology	NOUN
fnp-6285	45	9	for	for	ADP
fnp-6285	45	10	precision	precision	NOUN
fnp-6285	45	11	medicine	medicine	NOUN
fnp-6285	45	12	in	in	ADP
fnp-6285	45	13	primary	primary	ADJ
fnp-6285	45	14	cns	cns	NOUN
fnp-6285	45	15	lymphoma	lymphoma	NOUN
fnp-6285	45	16	noemie	noemie	VERB
fnp-6285	45	17	barillot1	barillot1	PROPN
fnp-6285	45	18	,	,	PUNCT
fnp-6285	45	19	isaias	isaias	PROPN
fnp-6285	45	20	hernández	hernández	PROPN
fnp-6285	45	21	verdin1	verdin1	PROPN
fnp-6285	45	22	,	,	PUNCT
fnp-6285	45	23	lucas	lucas	PROPN
fnp-6285	45	24	rincón	rincón	PROPN
fnp-6285	45	25	de	de	PROPN
fnp-6285	45	26	la	la	PROPN
fnp-6285	45	27	rosa1	rosa1	PROPN
fnp-6285	45	28	,	,	PUNCT
fnp-6285	45	29	roser	roser	PROPN
fnp-6285	45	30	velasco2	velasco2	NOUN
fnp-6285	45	31	,	,	PUNCT
fnp-6285	45	32	fanny	fanny	ADJ
fnp-6285	45	33	drieux3	drieux3	PROPN
fnp-6285	45	34	,	,	PUNCT
fnp-6285	45	35	elena	elena	NOUN
fnp-6285	45	36	-	-	PUNCT
fnp-6285	45	37	liana	liana	PROPN
fnp-6285	45	38	veresezan3	veresezan3	PROPN
fnp-6285	45	39	,	,	PUNCT
fnp-6285	45	40	bertrand	bertrand	PROPN
fnp-6285	45	41	mathon4	mathon4	PROPN
fnp-6285	45	42	,	,	PUNCT
fnp-6285	45	43	eva	eva	PROPN
fnp-6285	45	44	kirasic1	kirasic1	PROPN
fnp-6285	45	45	,	,	PUNCT
fnp-6285	45	46	noemí	noemí	ADJ
fnp-6285	45	47	vidal5	vidal5	PROPN
fnp-6285	45	48	,	,	PUNCT
fnp-6285	45	49	eva	eva	PROPN
fnp-6285	45	50	gonzález	gonzález	PROPN
fnp-6285	45	51	-	-	PUNCT
fnp-6285	45	52	barca6	barca6	PROPN
fnp-6285	45	53	,	,	PUNCT
fnp-6285	45	54	fina	fina	PROPN
fnp-6285	45	55	climent	climent	PROPN
fnp-6285	45	56	esteller7	esteller7	PROPN
fnp-6285	45	57	,	,	PUNCT
fnp-6285	45	58	patricia	patricia	PROPN
fnp-6285	45	59	lópez8	lópez8	PROPN
fnp-6285	45	60	,	,	PUNCT
fnp-6285	45	61	yah	yah	NOUN
fnp-6285	45	62	-	-	PUNCT
fnp-6285	45	63	se	se	PROPN
fnp-6285	45	64	abada4	abada4	PROPN
fnp-6285	45	65	,	,	PUNCT
fnp-6285	45	66	michael	michael	PROPN
fnp-6285	45	67	heming9	heming9	PROPN
fnp-6285	45	68	,	,	PUNCT
fnp-6285	45	69	gerd	gerd	NOUN
fnp-6285	45	70	meyer	meyer	PROPN
fnp-6285	45	71	zu	zu	PROPN
fnp-6285	45	72	hörste9	hörste9	PROPN
fnp-6285	45	73	,	,	PUNCT
fnp-6285	45	74	olivier	olivier	PROPN
fnp-6285	45	75	grauer10	grauer10	PROPN
fnp-6285	45	76	,	,	PUNCT
fnp-6285	45	77	magali	magali	PROPN
fnp-6285	45	78	le	le	X
fnp-6285	45	79	garff	garff	PROPN
fnp-6285	45	80	-	-	PUNCT
fnp-6285	45	81	tavernier11	tavernier11	PROPN
fnp-6285	45	82	,	,	PUNCT
fnp-6285	45	83	frédéric	frédéric	PROPN
fnp-6285	45	84	davi12	davi12	PROPN
fnp-6285	45	85	,	,	PUNCT
fnp-6285	45	86	albert	albert	PROPN
fnp-6285	45	87	pons	pons	PROPN
fnp-6285	45	88	-	-	PUNCT
fnp-6285	45	89	escoda13,lucia	escoda13,lucia	PROPN
fnp-6285	45	90	nichelli4,sylvain	nichelli4,sylvain	PUNCT
fnp-6285	46	1	choquet4,fabrice	choquet4,fabrice	PROPN
fnp-6285	46	2	jardin14,caroline	jardin14,caroline	PROPN
fnp-6285	46	3	houillier4,karima	houillier4,karima	NOUN
fnp-6285	46	4	mokhtari15	mokhtari15	NOUN
fnp-6285	46	5	,	,	PUNCT
fnp-6285	46	6	khe	khe	PROPN
fnp-6285	46	7	hoang	hoang	PROPN
fnp-6285	46	8	-	-	PUNCT
fnp-6285	46	9	xuan16	xuan16	PROPN
fnp-6285	46	10	,	,	PUNCT
fnp-6285	46	11	agusti	agusti	PROPN
fnp-6285	46	12	alentorn1	alentorn1	PROPN
fnp-6285	46	13	paris	paris	PROPN
fnp-6285	46	14	brain	brain	PROPN
fnp-6285	46	15	institute	institute	PROPN
fnp-6285	46	16	,	,	PUNCT
fnp-6285	46	17	paris	paris	PROPN
fnp-6285	46	18	,	,	PUNCT
fnp-6285	46	19	france	france	PROPN
fnp-6285	46	20	neuro	neuro	PROPN
fnp-6285	46	21	-	-	PUNCT
fnp-6285	46	22	oncology	oncology	NOUN
fnp-6285	46	23	unit	unit	NOUN
fnp-6285	46	24	,	,	PUNCT
fnp-6285	46	25	department	department	NOUN
fnp-6285	46	26	of	of	ADP
fnp-6285	46	27	neurology	neurology	NOUN
fnp-6285	46	28	,	,	PUNCT
fnp-6285	46	29	hospital	hospital	NOUN
fnp-6285	46	30	universitari	universitari	PROPN
fnp-6285	46	31	de	de	X
fnp-6285	46	32	bellvitge	bellvitge	VERB
fnp-6285	46	33	institut	institut	PROPN
fnp-6285	46	34	català	català	PROPN
fnp-6285	46	35	d'onco	d'onco	PROPN
fnp-6285	46	36	-	-	PUNCT
fnp-6285	46	37	logia	logia	PROPN
fnp-6285	46	38	(	(	PUNCT
fnp-6285	46	39	ico	ico	PROPN
fnp-6285	46	40	)	)	PUNCT
fnp-6285	46	41	,	,	PUNCT
fnp-6285	46	42	barcelona	barcelona	PROPN
fnp-6285	46	43	,	,	PUNCT
fnp-6285	46	44	spain	spain	PROPN
fnp-6285	46	45	centre	centre	PROPN
fnp-6285	46	46	henri	henri	PROPN
fnp-6285	46	47	becquerel	becquerel	PROPN
fnp-6285	46	48	,	,	PUNCT
fnp-6285	46	49	rouen	rouen	PROPN
fnp-6285	46	50	,	,	PUNCT
fnp-6285	46	51	france	france	PROPN
fnp-6285	46	52	groupe	groupe	PROPN
fnp-6285	46	53	hospitalier	hospitalier	PROPN
fnp-6285	46	54	pitié	pitié	PROPN
fnp-6285	46	55	salpêtrière	salpêtrière	PROPN
fnp-6285	46	56	,	,	PUNCT
fnp-6285	46	57	paris	paris	PROPN
fnp-6285	46	58	,	,	PUNCT
fnp-6285	46	59	france	france	PROPN
fnp-6285	46	60	pathology	pathology	PROPN
fnp-6285	46	61	department	department	PROPN
fnp-6285	46	62	,	,	PUNCT
fnp-6285	46	63	hospital	hospital	NOUN
fnp-6285	46	64	universitari	universitari	PROPN
fnp-6285	46	65	de	de	X
fnp-6285	46	66	bellvitge	bellvitge	VERB
fnp-6285	46	67	,	,	PUNCT
fnp-6285	46	68	barcelona	barcelona	PROPN
fnp-6285	46	69	,	,	PUNCT
fnp-6285	46	70	spain	spain	PROPN
fnp-6285	46	71	institut	institut	PROPN
fnp-6285	46	72	català	català	PROPN
fnp-6285	46	73	d'oncologia	d'oncologia	PROPN
fnp-6285	46	74	(	(	PUNCT
fnp-6285	46	75	ico	ico	PROPN
fnp-6285	46	76	)	)	PUNCT
fnp-6285	46	77	institut	institut	PROPN
fnp-6285	46	78	d'investigació	d'investigació	PROPN
fnp-6285	46	79	biomèdica	biomèdica	PROPN
fnp-6285	46	80	de	de	PROPN
fnp-6285	46	81	bellvitge	bellvitge	VERB
fnp-6285	46	82	(	(	PUNCT
fnp-6285	46	83	idibell	idibell	NOUN
fnp-6285	46	84	)	)	PUNCT
fnp-6285	46	85	,	,	PUNCT
fnp-6285	46	86	barcelona	barcelona	PROPN
fnp-6285	46	87	,	,	PUNCT
fnp-6285	46	88	spain	spain	PROPN
fnp-6285	46	89	hospital	hospital	PROPN
fnp-6285	46	90	universitari	universitari	PROPN
fnp-6285	46	91	de	de	X
fnp-6285	46	92	bellvitge	bellvitge	VERB
fnp-6285	46	93	,	,	PUNCT
fnp-6285	46	94	barcelona	barcelona	PROPN
fnp-6285	46	95	,	,	PUNCT
fnp-6285	46	96	spain	spain	PROPN
fnp-6285	46	97	clinical	clinical	PROPN
fnp-6285	46	98	hematology	hematology	PROPN
fnp-6285	46	99	department	department	PROPN
fnp-6285	46	100	,	,	PUNCT
fnp-6285	46	101	institut	institut	PROPN
fnp-6285	46	102	català	català	PROPN
fnp-6285	46	103	d'oncologia	d'oncologia	PROPN
fnp-6285	46	104	(	(	PUNCT
fnp-6285	46	105	ico	ico	PROPN
fnp-6285	46	106	)	)	PUNCT
fnp-6285	46	107	,	,	PUNCT
fnp-6285	46	108	barcelona	barcelona	PROPN
fnp-6285	46	109	,	,	PUNCT
fnp-6285	46	110	spain	spain	PROPN
fnp-6285	46	111	department	department	PROPN
fnp-6285	46	112	of	of	ADP
fnp-6285	46	113	neurology	neurology	NOUN
fnp-6285	46	114	with	with	ADP
fnp-6285	46	115	institute	institute	PROPN
fnp-6285	46	116	of	of	ADP
fnp-6285	46	117	translational	translational	ADJ
fnp-6285	46	118	neurology	neurology	NOUN
fnp-6285	46	119	,	,	PUNCT
fnp-6285	46	120	university	university	NOUN
fnp-6285	46	121	hospital	hospital	NOUN
fnp-6285	46	122	münster	münster	NOUN
fnp-6285	46	123	,	,	PUNCT
fnp-6285	46	124	germany	germany	PROPN
fnp-6285	46	125	department	department	PROPN
fnp-6285	46	126	of	of	ADP
fnp-6285	46	127	neurology	neurology	NOUN
fnp-6285	46	128	with	with	ADP
fnp-6285	46	129	institute	institute	PROPN
fnp-6285	46	130	of	of	ADP
fnp-6285	46	131	translational	translational	ADJ
fnp-6285	46	132	neurology	neurology	NOUN
fnp-6285	46	133	,	,	PUNCT
fnp-6285	46	134	university	university	NOUN
fnp-6285	46	135	hospital	hospital	NOUN
fnp-6285	46	136	münster	münster	NOUN
fnp-6285	46	137	,	,	PUNCT
fnp-6285	46	138	germany	germany	PROPN
fnp-6285	46	139	centre	centre	PROPN
fnp-6285	46	140	de	de	X
fnp-6285	46	141	recherche	recherche	X
fnp-6285	46	142	des	des	X
fnp-6285	46	143	cordeliers	cordelier	NOUN
fnp-6285	46	144	,	,	PUNCT
fnp-6285	46	145	cell	cell	NOUN
fnp-6285	46	146	death	death	NOUN
fnp-6285	46	147	and	and	CCONJ
fnp-6285	46	148	drug	drug	NOUN
fnp-6285	46	149	resistance	resistance	NOUN
fnp-6285	46	150	in	in	ADP
fnp-6285	46	151	lymphoproliferative	lymphoproliferative	ADJ
fnp-6285	46	152	disorders	disorder	NOUN
fnp-6285	46	153	team	team	NOUN
fnp-6285	46	154	,	,	PUNCT
fnp-6285	46	155	sorbonne	sorbonne	PROPN
fnp-6285	46	156	université	université	PROPN
fnp-6285	46	157	,	,	PUNCT
fnp-6285	46	158	department	department	NOUN
fnp-6285	46	159	of	of	ADP
fnp-6285	46	160	biological	biological	ADJ
fnp-6285	46	161	haematology	haematology	NOUN
fnp-6285	46	162	,	,	PUNCT
fnp-6285	46	163	ap	ap	PROPN
fnp-6285	46	164	-	-	PUNCT
fnp-6285	46	165	hp	hp	PROPN
fnp-6285	46	166	,	,	PUNCT
fnp-6285	46	167	pitiésalp	pitiésalp	PROPN
fnp-6285	46	168	,	,	PUNCT
fnp-6285	46	169	paris	paris	PROPN
fnp-6285	46	170	,	,	PUNCT
fnp-6285	46	171	france	france	PROPN
fnp-6285	46	172	hematology	hematology	PROPN
fnp-6285	46	173	department	department	PROPN
fnp-6285	46	174	,	,	PUNCT
fnp-6285	46	175	hôpital	hôpital	PROPN
fnp-6285	46	176	de	de	PROPN
fnp-6285	46	177	la	la	PROPN
fnp-6285	46	178	pitié	pitié	PROPN
fnp-6285	46	179	-	-	PUNCT
fnp-6285	46	180	salpêtrière	salpêtrière	PROPN
fnp-6285	46	181	,	,	PUNCT
fnp-6285	46	182	ap	ap	PROPN
fnp-6285	46	183	-	-	PUNCT
fnp-6285	46	184	hp	hp	PROPN
fnp-6285	46	185	,	,	PUNCT
fnp-6285	46	186	pitiésalp	pitiésalp	PROPN
fnp-6285	46	187	,	,	PUNCT
fnp-6285	46	188	paris	paris	PROPN
fnp-6285	46	189	,	,	PUNCT
fnp-6285	46	190	france	france	PROPN
fnp-6285	46	191	radiology	radiology	PROPN
fnp-6285	46	192	department	department	PROPN
fnp-6285	46	193	,	,	PUNCT
fnp-6285	46	194	institut	institut	PROPN
fnp-6285	46	195	de	de	PROPN
fnp-6285	46	196	diagnòstic	diagnòstic	PROPN
fnp-6285	46	197	per	per	ADP
fnp-6285	46	198	laimatge	laimatge	PROPN
fnp-6285	46	199	(	(	PUNCT
fnp-6285	46	200	idi	idi	PROPN
fnp-6285	46	201	)	)	PUNCT
fnp-6285	46	202	,	,	PUNCT
fnp-6285	46	203	hospital	hospital	NOUN
fnp-6285	46	204	universitari	universitari	PROPN
fnp-6285	46	205	de	de	X
fnp-6285	46	206	bellvitge	bellvitge	VERB
fnp-6285	46	207	,	,	PUNCT
fnp-6285	46	208	barce	barce	PROPN
fnp-6285	46	209	-	-	PUNCT
fnp-6285	46	210	lona	lona	PROPN
fnp-6285	46	211	,	,	PUNCT
fnp-6285	46	212	spain	spain	PROPN
fnp-6285	46	213	centre	centre	PROPN
fnp-6285	46	214	henri	henri	PROPN
fnp-6285	46	215	bequerel	bequerel	PROPN
fnp-6285	46	216	,	,	PUNCT
fnp-6285	46	217	rouen	rouen	PROPN
fnp-6285	46	218	,	,	PUNCT
fnp-6285	46	219	france	france	PROPN
fnp-6285	46	220	neuropathology	neuropathology	PROPN
fnp-6285	46	221	department	department	PROPN
fnp-6285	46	222	,	,	PUNCT
fnp-6285	46	223	assistance	assistance	NOUN
fnp-6285	46	224	publique	publique	ADJ
fnp-6285	46	225	-	-	PUNCT
fnp-6285	46	226	hôpitaux	hôpitaux	PROPN
fnp-6285	46	227	de	de	X
fnp-6285	46	228	paris	paris	PROPN
fnp-6285	46	229	,	,	PUNCT
fnp-6285	46	230	universitary	universitary	ADJ
fnp-6285	46	231	hospital	hospital	NOUN
fnp-6285	46	232	la	la	PROPN
fnp-6285	46	233	pitié	pitié	PROPN
fnp-6285	46	234	salpê	salpê	NOUN
fnp-6285	46	235	-	-	PUNCT
fnp-6285	46	236	trière	trière	NOUN
fnp-6285	46	237	-	-	PUNCT
fnp-6285	46	238	charles	charles	NOUN
fnp-6285	46	239	foix	foix	PROPN
fnp-6285	46	240	,	,	PUNCT
fnp-6285	46	241	and	and	CCONJ
fnp-6285	46	242	sorbonne	sorbonne	PROPN
fnp-6285	46	243	universités	universités	PROPN
fnp-6285	46	244	,	,	PUNCT
fnp-6285	46	245	paris	paris	PROPN
fnp-6285	46	246	,	,	PUNCT
fnp-6285	46	247	france	france	PROPN
fnp-6285	46	248	sorbonne	sorbonne	PROPN
fnp-6285	46	249	universités	universités	PROPN
fnp-6285	46	250	,	,	PUNCT
fnp-6285	46	251	upmc	upmc	PROPN
fnp-6285	46	252	univ	univ	PROPN
fnp-6285	46	253	paris	paris	PROPN
fnp-6285	46	254	06	06	NUM
fnp-6285	46	255	,	,	PUNCT
fnp-6285	46	256	umr	umr	PROPN
fnp-6285	46	257	s	s	PART
fnp-6285	46	258	1127	1127	NUM
fnp-6285	46	259	,	,	PUNCT
fnp-6285	46	260	paris	paris	PROPN
fnp-6285	46	261	,	,	PUNCT
fnp-6285	46	262	france	france	PROPN
fnp-6285	46	263	primary	primary	ADJ
fnp-6285	46	264	central	central	ADJ
fnp-6285	46	265	nervous	nervous	ADJ
fnp-6285	46	266	system	system	NOUN
fnp-6285	46	267	lymphoma	lymphoma	NOUN
fnp-6285	46	268	(	(	PUNCT
fnp-6285	46	269	pcnsl	pcnsl	NOUN
fnp-6285	46	270	)	)	PUNCT
fnp-6285	46	271	is	be	AUX
fnp-6285	46	272	an	an	DET
fnp-6285	46	273	aggressive	aggressive	ADJ
fnp-6285	46	274	subtype	subtype	NOUN
fnp-6285	46	275	of	of	ADP
fnp-6285	46	276	large	large	ADJ
fnp-6285	46	277	b	b	NOUN
fnp-6285	46	278	-	-	PUNCT
fnp-6285	46	279	cell	cell	NOUN
fnp-6285	46	280	lymphoma	lymphoma	NOUN
fnp-6285	46	281	(	(	PUNCT
fnp-6285	46	282	lbcl	lbcl	NOUN
fnp-6285	46	283	)	)	PUNCT
fnp-6285	46	284	with	with	ADP
fnp-6285	46	285	poor	poor	ADJ
fnp-6285	46	286	prognosis	prognosis	NOUN
fnp-6285	46	287	.	.	PUNCT
fnp-6285	47	1	we	we	PRON
fnp-6285	47	2	developed	develop	VERB
fnp-6285	47	3	a	a	DET
fnp-6285	47	4	novel	novel	ADJ
fnp-6285	47	5	digital	digital	ADJ
fnp-6285	47	6	pathology	pathology	NOUN
fnp-6285	47	7	approach	approach	NOUN
fnp-6285	47	8	to	to	PART
fnp-6285	47	9	classify	classify	VERB
fnp-6285	47	10	pcnsl	pcnsl	NOUN
fnp-6285	47	11	,	,	PUNCT
fnp-6285	47	12	detect	detect	VERB
fnp-6285	47	13	myd88	myd88	ADJ
fnp-6285	47	14	l265p	l265p	ADJ
fnp-6285	47	15	mutations	mutation	NOUN
fnp-6285	47	16	,	,	PUNCT
fnp-6285	47	17	and	and	CCONJ
fnp-6285	47	18	predict	predict	VERB
fnp-6285	47	19	outcomes	outcome	NOUN
fnp-6285	47	20	using	use	VERB
fnp-6285	47	21	hematoxylin	hematoxylin	NOUN
fnp-6285	47	22	-	-	PUNCT
fnp-6285	47	23	eosin	eosin	NOUN
fnp-6285	47	24	(	(	PUNCT
fnp-6285	47	25	h&e	h&e	PROPN
fnp-6285	47	26	)	)	PUNCT
fnp-6285	47	27	and	and	CCONJ
fnp-6285	47	28	immunohistochemistry	immunohistochemistry	NOUN
fnp-6285	47	29	(	(	PUNCT
fnp-6285	47	30	ihc	ihc	PROPN
fnp-6285	47	31	)	)	PUNCT
fnp-6285	47	32	samples	sample	NOUN
fnp-6285	47	33	.	.	PUNCT
fnp-6285	48	1	utilizing	utilize	VERB
fnp-6285	48	2	datasets	dataset	NOUN
fnp-6285	48	3	from	from	ADP
fnp-6285	48	4	over	over	ADP
fnp-6285	48	5	400	400	NUM
fnp-6285	48	6	patients	patient	NOUN
fnp-6285	48	7	,	,	PUNCT
fnp-6285	48	8	our	our	PRON
fnp-6285	48	9	deep	deep	ADJ
fnp-6285	48	10	learning	learning	NOUN
fnp-6285	48	11	models	model	NOUN
fnp-6285	48	12	achieved	achieve	VERB
fnp-6285	48	13	a	a	DET
fnp-6285	48	14	median	median	ADJ
fnp-6285	48	15	auroc	auroc	NOUN
fnp-6285	48	16	of	of	ADP
fnp-6285	48	17	0.9	0.9	NUM
fnp-6285	49	1	[	[	X
fnp-6285	49	2	iqr	iqr	NOUN
fnp-6285	49	3	0.85–0.93	0.85–0.93	NOUN
fnp-6285	49	4	]	]	X
fnp-6285	49	5	in	in	ADP
fnp-6285	49	6	categorizing	categorize	VERB
fnp-6285	49	7	pcnsl	pcnsl	NOUN
fnp-6285	49	8	molecular	molecular	ADJ
fnp-6285	49	9	clusters	cluster	NOUN
fnp-6285	49	10	.	.	PUNCT
fnp-6285	50	1	spatial	spatial	ADJ
fnp-6285	50	2	transcriptomics	transcriptomic	NOUN
fnp-6285	50	3	and	and	CCONJ
fnp-6285	50	4	single	single	ADJ
fnp-6285	50	5	-	-	PUNCT
fnp-6285	50	6	cell	cell	NOUN
fnp-6285	50	7	rna	rna	NOUN
fnp-6285	50	8	sequencing	sequencing	NOUN
fnp-6285	50	9	revealed	reveal	VERB
fnp-6285	50	10	significant	significant	ADJ
fnp-6285	50	11	intra	intra	ADJ
fnp-6285	50	12	-	-	ADJ
fnp-6285	50	13	tumoral	tumoral	ADJ
fnp-6285	50	14	heterogeneity	heterogeneity	NOUN
fnp-6285	50	15	.	.	PUNCT
fnp-6285	51	1	additionally	additionally	ADV
fnp-6285	51	2	,	,	PUNCT
fnp-6285	51	3	partial	partial	ADJ
fnp-6285	51	4	least	least	ADJ
fnp-6285	51	5	squares	square	NOUN
fnp-6285	51	6	(	(	PUNCT
fnp-6285	51	7	pls	pls	INTJ
fnp-6285	51	8	)	)	PUNCT
fnp-6285	51	9	cox	cox	PROPN
fnp-6285	51	10	models	model	NOUN
fnp-6285	51	11	integrating	integrate	VERB
fnp-6285	51	12	cell	cell	NOUN
fnp-6285	51	13	radiomics	radiomic	NOUN
fnp-6285	51	14	and	and	CCONJ
fnp-6285	51	15	clinical	clinical	ADJ
fnp-6285	51	16	features	feature	NOUN
fnp-6285	51	17	achieved	achieve	VERB
fnp-6285	51	18	a	a	DET
fnp-6285	51	19	c	c	NOUN
fnp-6285	51	20	-	-	PUNCT
fnp-6285	51	21	index	index	NOUN
fnp-6285	51	22	above	above	ADP
fnp-6285	51	23	0.9	0.9	NUM
fnp-6285	51	24	across	across	ADP
fnp-6285	51	25	datasets	dataset	NOUN
fnp-6285	51	26	.	.	PUNCT
fnp-6285	52	1	remarkably	remarkably	ADV
fnp-6285	52	2	,	,	PUNCT
fnp-6285	52	3	molecular	molecular	ADJ
fnp-6285	52	4	group	group	NOUN
fnp-6285	52	5	classifications	classification	NOUN
fnp-6285	52	6	derived	derive	VERB
fnp-6285	52	7	from	from	ADP
fnp-6285	52	8	multi	multi	ADJ
fnp-6285	52	9	-	-	ADJ
fnp-6285	52	10	omics	omics	ADJ
fnp-6285	52	11	data	datum	NOUN
fnp-6285	52	12	were	be	AUX
fnp-6285	52	13	accurately	accurately	ADV
fnp-6285	52	14	replicated	replicate	VERB
fnp-6285	52	15	using	use	VERB
fnp-6285	52	16	h&e	h&e	PROPN
fnp-6285	52	17	samples	sample	NOUN
fnp-6285	52	18	alone	alone	ADV
fnp-6285	52	19	.	.	PUNCT
fnp-6285	53	1	these	these	DET
fnp-6285	53	2	findings	finding	NOUN
fnp-6285	53	3	demonstrate	demonstrate	VERB
fnp-6285	53	4	the	the	DET
fnp-6285	53	5	potential	potential	NOUN
fnp-6285	53	6	of	of	ADP
fnp-6285	53	7	artificial	artificial	ADJ
fnp-6285	53	8	intelligence	intelligence	NOUN
fnp-6285	53	9	to	to	PART
fnp-6285	53	10	streamline	streamline	VERB
fnp-6285	53	11	the	the	DET
fnp-6285	53	12	clinical	clinical	ADJ
fnp-6285	53	13	implementation	implementation	NOUN
fnp-6285	53	14	of	of	ADP
fnp-6285	53	15	precision	precision	NOUN
fnp-6285	53	16	medicine	medicine	NOUN
fnp-6285	53	17	for	for	ADP
fnp-6285	53	18	lbcl	lbcl	NOUN
fnp-6285	53	19	and	and	CCONJ
fnp-6285	53	20	pcnsl	pcnsl	NOUN
fnp-6285	53	21	,	,	PUNCT
fnp-6285	53	22	enabling	enable	VERB
fnp-6285	53	23	more	more	ADV
fnp-6285	53	24	effective	effective	ADJ
fnp-6285	53	25	and	and	CCONJ
fnp-6285	53	26	tailored	tailor	VERB
fnp-6285	53	27	therapeutic	therapeutic	ADJ
fnp-6285	53	28	strategies	strategy	NOUN
fnp-6285	53	29	.	.	PUNCT
fnp-6285	53	30	  	  	SPACE
fnp-6285	54	1	free	free	ADJ
fnp-6285	54	2	neuropathol	neuropathol	NOUN
fnp-6285	54	3	6:2:9–10	6:2:9–10	NUM
fnp-6285	54	4	disease	disease	NOUN
fnp-6285	54	5	-	-	PUNCT
fnp-6285	54	6	defining	define	VERB
fnp-6285	54	7	catalytically	catalytically	ADV
fnp-6285	54	8	inactive	inactive	ADJ
fnp-6285	54	9	protein	protein	NOUN
fnp-6285	54	10	kinase	kinase	NOUN
fnp-6285	54	11	c	c	PROPN
fnp-6285	54	12	alpha	alpha	PROPN
fnp-6285	54	13	mutation	mutation	NOUN
fnp-6285	54	14	is	be	AUX
fnp-6285	54	15	a	a	DET
fnp-6285	54	16	driver	driver	NOUN
fnp-6285	54	17	in	in	ADP
fnp-6285	54	18	chordoid	chordoid	NOUN
fnp-6285	54	19	glioma	glioma	NOUN
fnp-6285	54	20	by	by	ADP
fnp-6285	54	21	pathway	pathway	NOUN
fnp-6285	54	22	rewiring	rewiring	PROPN
fnp-6285	54	23	charlotte	charlotte	PROPN
fnp-6285	54	24	bellamy1,$	bellamy1,$	PROPN
fnp-6285	54	25	,	,	PUNCT
fnp-6285	54	26	hannah	hannah	PROPN
fnp-6285	54	27	tovell2,$	tovell2,$	PROPN
fnp-6285	54	28	,	,	PUNCT
fnp-6285	54	29	selina	selina	PROPN
fnp-6285	54	30	schwaighofer3	schwaighofer3	PROPN
fnp-6285	54	31	,	,	PUNCT
fnp-6285	54	32	timothy	timothy	PROPN
fnp-6285	54	33	r.	r.	PROPN
fnp-6285	54	34	baffi2,4	baffi2,4	PROPN
fnp-6285	54	35	,	,	PUNCT
fnp-6285	54	36	*	*	PROPN
fnp-6285	54	37	,	,	PUNCT
fnp-6285	54	38	janan	janan	PROPN
fnp-6285	54	39	arslan1	arslan1	PROPN
fnp-6285	54	40	,	,	PUNCT
fnp-6285	54	41	quentin	quentin	PROPN
fnp-6285	54	42	letourneur5	letourneur5	PROPN
fnp-6285	54	43	,	,	PUNCT
fnp-6285	54	44	florent	florent	NOUN
fnp-6285	54	45	dingli6	dingli6	NOUN
fnp-6285	54	46	,	,	PUNCT
fnp-6285	54	47	damarys	damarys	PROPN
fnp-6285	54	48	loew6	loew6	NOUN
fnp-6285	54	49	,	,	PUNCT
fnp-6285	54	50	alexandr	alexandr	NOUN
fnp-6285	54	51	kornev2	kornev2	PROPN
fnp-6285	54	52	,	,	PUNCT
fnp-6285	54	53	*	*	PUNCT
fnp-6285	54	54	*	*	PUNCT
fnp-6285	54	55	,	,	PUNCT
fnp-6285	54	56	julie	julie	PROPN
fnp-6285	54	57	lerond1	lerond1	PROPN
fnp-6285	54	58	,	,	PUNCT
fnp-6285	54	59	tiffany	tiffany	PROPN
fnp-6285	54	60	kao2,4	kao2,4	PROPN
fnp-6285	54	61	,	,	PUNCT
fnp-6285	54	62	stephane	stephane	PROPN
fnp-6285	54	63	liva7	liva7	PROPN
fnp-6285	54	64	,	,	PUNCT
fnp-6285	54	65	brigitte	brigitte	PROPN
fnp-6285	54	66	izac8	izac8	PROPN
fnp-6285	54	67	,	,	PUNCT
fnp-6285	54	68	muriel	muriel	PROPN
fnp-6285	54	69	andrieu8	andrieu8	PROPN
fnp-6285	54	70	,	,	PUNCT
fnp-6285	54	71	homa	homa	PROPN
fnp-6285	54	72	adle	adle	PROPN
fnp-6285	54	73	-	-	PUNCT
fnp-6285	54	74	biassette9	biassette9	NOUN
fnp-6285	54	75	,	,	PUNCT
fnp-6285	54	76	jean	jean	PROPN
fnp-6285	54	77	-	-	PUNCT
fnp-6285	54	78	vianney	vianney	PROPN
fnp-6285	54	79	barnier10	barnier10	NOUN
fnp-6285	54	80	,	,	PUNCT
fnp-6285	54	81	eduard	eduard	PROPN
fnp-6285	54	82	stefan3	stefan3	PROPN
fnp-6285	54	83	,	,	PUNCT
fnp-6285	54	84	marc	marc	PROPN
fnp-6285	54	85	sanson1,11	sanson1,11	PROPN
fnp-6285	54	86	,	,	PUNCT
fnp-6285	54	87	&	&	CCONJ
fnp-6285	54	88	,	,	PUNCT
fnp-6285	54	89	alexandra	alexandra	PROPN
fnp-6285	54	90	c.	c.	PROPN
fnp-6285	54	91	newton2	newton2	PROPN
fnp-6285	54	92	,	,	PUNCT
fnp-6285	54	93	franck	franck	PROPN
fnp-6285	54	94	bielle1,12	bielle1,12	PROPN
fnp-6285	54	95	paris	paris	PROPN
fnp-6285	54	96	brain	brain	PROPN
fnp-6285	54	97	institute	institute	PROPN
fnp-6285	54	98	,	,	PUNCT
fnp-6285	54	99	paris	paris	PROPN
fnp-6285	54	100	,	,	PUNCT
fnp-6285	54	101	france	france	PROPN
fnp-6285	54	102	cruk	cruk	PROPN
fnp-6285	54	103	scotland	scotland	PROPN
fnp-6285	54	104	institute	institute	PROPN
fnp-6285	54	105	,	,	PUNCT
fnp-6285	54	106	glasgow	glasgow	PROPN
fnp-6285	54	107	,	,	PUNCT
fnp-6285	54	108	scotland	scotland	PROPN
fnp-6285	54	109	,	,	PUNCT
fnp-6285	54	110	united	united	PROPN
fnp-6285	54	111	kingdom	kingdom	PROPN
fnp-6285	54	112	leopold	leopold	PROPN
fnp-6285	54	113	-	-	PUNCT
fnp-6285	54	114	franzens	franzens	PROPN
fnp-6285	54	115	-	-	PUNCT
fnp-6285	54	116	universität	universität	NOUN
fnp-6285	54	117	innsbruck	innsbruck	NOUN
fnp-6285	54	118	,	,	PUNCT
fnp-6285	54	119	innsbruck	innsbruck	PROPN
fnp-6285	54	120	,	,	PUNCT
fnp-6285	54	121	tirol	tirol	PROPN
fnp-6285	54	122	,	,	PUNCT
fnp-6285	54	123	austria	austria	PROPN
fnp-6285	54	124	department	department	PROPN
fnp-6285	54	125	of	of	ADP
fnp-6285	54	126	pharmacology	pharmacology	NOUN
fnp-6285	54	127	,	,	PUNCT
fnp-6285	54	128	university	university	PROPN
fnp-6285	54	129	of	of	ADP
fnp-6285	54	130	california	california	PROPN
fnp-6285	54	131	at	at	ADP
fnp-6285	54	132	san	san	PROPN
fnp-6285	54	133	diego	diego	PROPN
fnp-6285	54	134	,	,	PUNCT
fnp-6285	54	135	california	california	PROPN
fnp-6285	54	136	,	,	PUNCT
fnp-6285	54	137	usa	usa	PROPN
fnp-6285	54	138	sorbonne	sorbonne	PROPN
fnp-6285	54	139	université	université	PROPN
fnp-6285	54	140	,	,	PUNCT
fnp-6285	54	141	ap	ap	PROPN
fnp-6285	54	142	-	-	PUNCT
fnp-6285	54	143	hp	hp	PROPN
fnp-6285	54	144	,	,	PUNCT
fnp-6285	54	145	siric	siric	ADJ
fnp-6285	54	146	curamus	curamus	NOUN
fnp-6285	54	147	,	,	PUNCT
fnp-6285	54	148	paris	paris	PROPN
fnp-6285	54	149	,	,	PUNCT
fnp-6285	54	150	france	france	PROPN
fnp-6285	54	151	institut	institut	PROPN
fnp-6285	54	152	curie	curie	PROPN
fnp-6285	54	153	,	,	PUNCT
fnp-6285	54	154	psl	psl	PROPN
fnp-6285	54	155	research	research	PROPN
fnp-6285	54	156	university	university	PROPN
fnp-6285	54	157	,	,	PUNCT
fnp-6285	54	158	centre	centre	NOUN
fnp-6285	54	159	de	de	X
fnp-6285	54	160	recherche	recherche	X
fnp-6285	54	161	,	,	PUNCT
fnp-6285	54	162	curiecoretech	curiecoretech	NOUN
fnp-6285	54	163	spectrométrie	spectrométrie	VERB
fnp-6285	54	164	de	de	X
fnp-6285	54	165	masse	masse	PROPN
fnp-6285	54	166	protéomique	protéomique	NOUN
fnp-6285	54	167	,	,	PUNCT
fnp-6285	54	168	paris	paris	PROPN
fnp-6285	54	169	,	,	PUNCT
fnp-6285	54	170	france	france	PROPN
fnp-6285	54	171	institut	institut	PROPN
fnp-6285	54	172	curie	curie	PROPN
fnp-6285	54	173	,	,	PUNCT
fnp-6285	54	174	service	service	NOUN
fnp-6285	54	175	bioinformatique	bioinformatique	NOUN
fnp-6285	54	176	,	,	PUNCT
fnp-6285	54	177	paris	paris	PROPN
fnp-6285	54	178	,	,	PUNCT
fnp-6285	54	179	france	france	PROPN
fnp-6285	54	180	institut	institut	PROPN
fnp-6285	54	181	cochin	cochin	PROPN
fnp-6285	54	182	,	,	PUNCT
fnp-6285	54	183	paris	paris	PROPN
fnp-6285	54	184	,	,	PUNCT
fnp-6285	54	185	france	france	PROPN
fnp-6285	54	186	service	service	PROPN
fnp-6285	54	187	d’anatomie	d’anatomie	VERB
fnp-6285	54	188	et	et	NOUN
fnp-6285	54	189	cytologie	cytologie	NOUN
fnp-6285	54	190	pathologiques	pathologique	NOUN
fnp-6285	54	191	,	,	PUNCT
fnp-6285	54	192	faculté	faculté	PROPN
fnp-6285	54	193	de	de	X
fnp-6285	54	194	médecine	médecine	PROPN
fnp-6285	54	195	,	,	PUNCT
fnp-6285	54	196	université	université	PROPN
fnp-6285	54	197	paris	paris	PROPN
fnp-6285	54	198	diderot	diderot	NOUN
fnp-6285	54	199	,	,	PUNCT
fnp-6285	54	200	paris	paris	PROPN
fnp-6285	54	201	,	,	PUNCT
fnp-6285	54	202	france	france	PROPN
fnp-6285	54	203	institut	institut	PROPN
fnp-6285	54	204	neuropsi	neuropsi	PROPN
fnp-6285	54	205	umr9197,cnrs	umr9197,cnrs	NOUN
fnp-6285	54	206	université	université	PROPN
fnp-6285	54	207	paris	paris	PROPN
fnp-6285	54	208	-	-	PUNCT
fnp-6285	54	209	saclay	saclay	NOUN
fnp-6285	54	210	,	,	PUNCT
fnp-6285	54	211	saclay	saclay	NOUN
fnp-6285	54	212	,	,	PUNCT
fnp-6285	54	213	france	france	PROPN
fnp-6285	54	214	sorbonne	sorbonne	PROPN
fnp-6285	54	215	université	université	PROPN
fnp-6285	54	216	,	,	PUNCT
fnp-6285	54	217	paris	paris	PROPN
fnp-6285	54	218	,	,	PUNCT
fnp-6285	54	219	france	france	PROPN
fnp-6285	54	220	centre	centre	PROPN
fnp-6285	54	221	de	de	X
fnp-6285	54	222	recherche	recherche	X
fnp-6285	54	223	de	de	X
fnp-6285	54	224	l'institut	l'institut	X
fnp-6285	54	225	du	du	PROPN
fnp-6285	54	226	cerveau	cerveau	PROPN
fnp-6285	54	227	et	et	PROPN
fnp-6285	54	228	de	de	PROPN
fnp-6285	54	229	la	la	PROPN
fnp-6285	54	230	moelle	moelle	PROPN
fnp-6285	54	231	epinière	epinière	PROPN
fnp-6285	54	232	,	,	PUNCT
fnp-6285	54	233	sorbonne	sorbonne	PROPN
fnp-6285	54	234	université	université	PROPN
fnp-6285	54	235	,	,	PUNCT
fnp-6285	54	236	paris	paris	PROPN
fnp-6285	54	237	,	,	PUNCT
fnp-6285	54	238	france	france	PROPN
fnp-6285	54	239	chordoid	chordoid	PROPN
fnp-6285	54	240	glioma	glioma	NOUN
fnp-6285	54	241	(	(	PUNCT
fnp-6285	54	242	chg	chg	NOUN
fnp-6285	54	243	)	)	PUNCT
fnp-6285	54	244	is	be	AUX
fnp-6285	54	245	a	a	DET
fnp-6285	54	246	rare	rare	ADJ
fnp-6285	54	247	low	low	ADJ
fnp-6285	54	248	-	-	PUNCT
fnp-6285	54	249	grade	grade	NOUN
fnp-6285	54	250	brain	brain	NOUN
fnp-6285	54	251	tumor	tumor	NOUN
fnp-6285	54	252	,	,	PUNCT
fnp-6285	54	253	characterized	characterize	VERB
fnp-6285	54	254	by	by	ADP
fnp-6285	54	255	a	a	DET
fnp-6285	54	256	novel	novel	ADJ
fnp-6285	54	257	recurrent	recurrent	NOUN
fnp-6285	54	258	point	point	NOUN
fnp-6285	54	259	mutation	mutation	NOUN
fnp-6285	54	260	,	,	PUNCT
fnp-6285	54	261	d463h	d463h	PROPN
fnp-6285	54	262	,	,	PUNCT
fnp-6285	54	263	in	in	ADP
fnp-6285	54	264	the	the	DET
fnp-6285	54	265	kinase	kinase	PROPN
fnp-6285	54	266	domain	domain	NOUN
fnp-6285	54	267	of	of	ADP
fnp-6285	54	268	protein	protein	NOUN
fnp-6285	54	269	kinase	kinase	NOUN
fnp-6285	54	270	c	c	PROPN
fnp-6285	54	271	alpha	alpha	NOUN
fnp-6285	54	272	(	(	PUNCT
fnp-6285	54	273	pkcα	pkcα	ADJ
fnp-6285	54	274	)	)	PUNCT
fnp-6285	54	275	.	.	PUNCT
fnp-6285	55	1	the	the	DET
fnp-6285	55	2	mutation	mutation	NOUN
fnp-6285	55	3	is	be	AUX
fnp-6285	55	4	always	always	ADV
fnp-6285	55	5	at	at	ADP
fnp-6285	55	6	this	this	DET
fnp-6285	55	7	position	position	NOUN
fnp-6285	55	8	and	and	CCONJ
fnp-6285	55	9	always	always	ADV
fnp-6285	55	10	to	to	ADP
fnp-6285	55	11	his	his	PRON
fnp-6285	55	12	suggesting	suggesting	NOUN
fnp-6285	55	13	it	it	PRON
fnp-6285	55	14	endows	endow	VERB
fnp-6285	55	15	a	a	DET
fnp-6285	55	16	unique	unique	ADJ
fnp-6285	55	17	function	function	NOUN
fnp-6285	55	18	beyond	beyond	ADP
fnp-6285	55	19	catalytic	catalytic	ADJ
fnp-6285	55	20	inactivation	inactivation	NOUN
fnp-6285	55	21	associated	associate	VERB
fnp-6285	55	22	with	with	ADP
fnp-6285	55	23	other	other	ADJ
fnp-6285	55	24	cancer	cancer	NOUN
fnp-6285	55	25	-	-	PUNCT
fnp-6285	55	26	associated	associate	VERB
fnp-6285	55	27	mutations	mutation	NOUN
fnp-6285	55	28	in	in	ADP
fnp-6285	55	29	pkcα	pkcα	NOUN
fnp-6285	55	30	.	.	PUNCT
fnp-6285	56	1	here	here	ADV
fnp-6285	56	2	we	we	PRON
fnp-6285	56	3	use	use	VERB
fnp-6285	56	4	in	in	ADP
fnp-6285	56	5	vitro	vitro	X
fnp-6285	56	6	and	and	CCONJ
fnp-6285	56	7	in	in	ADP
fnp-6285	56	8	cellulo	cellulo	ADJ
fnp-6285	56	9	activity	activity	NOUN
fnp-6285	56	10	assays	assay	NOUN
fnp-6285	56	11	to	to	PART
fnp-6285	56	12	show	show	VERB
fnp-6285	56	13	that	that	SCONJ
fnp-6285	56	14	d463h	d463h	PROPN
fnp-6285	56	15	is	be	AUX
fnp-6285	56	16	not	not	PART
fnp-6285	56	17	only	only	ADV
fnp-6285	56	18	catalytically	catalytically	ADV
fnp-6285	56	19	inactive	inactive	ADJ
fnp-6285	56	20	but	but	CCONJ
fnp-6285	56	21	is	be	AUX
fnp-6285	56	22	dominant	dominant	ADJ
fnp-6285	56	23	negative	negative	ADJ
fnp-6285	56	24	over	over	ADP
fnp-6285	56	25	endogenous	endogenous	ADJ
fnp-6285	56	26	pkcs	pkcs	NOUN
fnp-6285	56	27	and	and	CCONJ
fnp-6285	56	28	has	have	VERB
fnp-6285	56	29	a	a	DET
fnp-6285	56	30	rewired	rewire	VERB
fnp-6285	56	31	interactome	interactome	NOUN
fnp-6285	56	32	.	.	PUNCT
fnp-6285	57	1	specifically	specifically	ADV
fnp-6285	57	2	,	,	PUNCT
fnp-6285	57	3	phosphoproteomic	phosphoproteomic	NOUN
fnp-6285	57	4	,	,	PUNCT
fnp-6285	57	5	proximity	proximity	NOUN
fnp-6285	57	6	-	-	PUNCT
fnp-6285	57	7	driven	drive	VERB
fnp-6285	57	8	biotinylation	biotinylation	NOUN
fnp-6285	57	9	,	,	PUNCT
fnp-6285	57	10	and	and	CCONJ
fnp-6285	57	11	co	co	ADJ
fnp-6285	57	12	-	-	ADJ
fnp-6285	57	13	immunoprecipitation	immunoprecipitation	ADJ
fnp-6285	57	14	mass	mass	NOUN
fnp-6285	57	15	spectrometry	spectrometry	NOUN
fnp-6285	57	16	data	datum	NOUN
fnp-6285	57	17	from	from	ADP
fnp-6285	57	18	hek293	hek293	PROPN
fnp-6285	57	19	cells	cell	NOUN
fnp-6285	57	20	overexpressing	overexpresse	VERB
fnp-6285	57	21	pkcαd463h	pkcαd463h	NOUN
fnp-6285	57	22	identify	identify	VERB
fnp-6285	57	23	altered	alter	VERB
fnp-6285	57	24	phosphorylation	phosphorylation	NOUN
fnp-6285	57	25	of	of	ADP
fnp-6285	57	26	substrates	substrate	NOUN
fnp-6285	57	27	and	and	CCONJ
fnp-6285	57	28	binding	bind	VERB
fnp-6285	57	29	to	to	ADP
fnp-6285	57	30	multiple	multiple	ADJ
fnp-6285	57	31	proteins	protein	NOUN
fnp-6285	57	32	involved	involve	VERB
fnp-6285	57	33	in	in	ADP
fnp-6285	57	34	cell	cell	NOUN
fnp-6285	57	35	-	-	PUNCT
fnp-6285	57	36	cell	cell	NOUN
fnp-6285	57	37	junctions	junction	NOUN
fnp-6285	57	38	that	that	PRON
fnp-6285	57	39	wt	wt	ADP
fnp-6285	57	40	enzyme	enzyme	NOUN
fnp-6285	57	41	does	do	AUX
fnp-6285	57	42	not	not	PART
fnp-6285	57	43	interact	interact	VERB
fnp-6285	57	44	with	with	ADP
fnp-6285	57	45	.	.	PUNCT
fnp-6285	58	1	lastly	lastly	ADV
fnp-6285	58	2	,	,	PUNCT
fnp-6285	58	3	single	single	ADJ
fnp-6285	58	4	nuclei	nucleus	NOUN
fnp-6285	58	5	rnaseq	rnaseq	NOUN
fnp-6285	58	6	reveals	reveal	VERB
fnp-6285	58	7	that	that	SCONJ
fnp-6285	58	8	chgs	chgs	PROPN
fnp-6285	58	9	derive	derive	VERB
fnp-6285	58	10	from	from	ADP
fnp-6285	58	11	specialized	specialized	ADJ
fnp-6285	58	12	tanycytes	tanycyte	NOUN
fnp-6285	58	13	.	.	PUNCT
fnp-6285	59	1	our	our	PRON
fnp-6285	59	2	data	datum	NOUN
fnp-6285	59	3	suggest	suggest	VERB
fnp-6285	59	4	that	that	SCONJ
fnp-6285	59	5	this	this	DET
fnp-6285	59	6	fully	fully	ADV
fnp-6285	59	7	penetrant	penetrant	ADJ
fnp-6285	59	8	mutation	mutation	NOUN
fnp-6285	59	9	promotes	promote	VERB
fnp-6285	59	10	aberrant	aberrant	ADJ
fnp-6285	59	11	interaction	interaction	NOUN
fnp-6285	59	12	with	with	ADP
fnp-6285	59	13	unnatural	unnatural	ADJ
fnp-6285	59	14	partners	partner	NOUN
fnp-6285	59	15	to	to	PART
fnp-6285	59	16	impair	impair	VERB
fnp-6285	59	17	cell	cell	NOUN
fnp-6285	59	18	junction	junction	NOUN
fnp-6285	59	19	function	function	NOUN
fnp-6285	59	20	.	.	PUNCT
fnp-6285	59	21	  	  	SPACE
fnp-6285	60	1	free	free	ADJ
fnp-6285	60	2	neuropathol	neuropathol	NOUN
fnp-6285	60	3	6:2:11–12	6:2:11–12	NUM
fnp-6285	60	4	deciphering	decipher	VERB
fnp-6285	60	5	genetic	genetic	ADJ
fnp-6285	60	6	and	and	CCONJ
fnp-6285	60	7	epigenetic	epigenetic	ADJ
fnp-6285	60	8	of	of	ADP
fnp-6285	60	9	high	high	ADJ
fnp-6285	60	10	grade	grade	NOUN
fnp-6285	60	11	gliomas	glioma	NOUN
fnp-6285	60	12	with	with	ADP
fnp-6285	60	13	braf	braf	NOUN
fnp-6285	60	14	activating	activate	VERB
fnp-6285	60	15	alteration	alteration	NOUN
fnp-6285	60	16	is	be	AUX
fnp-6285	60	17	supporting	support	VERB
fnp-6285	60	18	the	the	DET
fnp-6285	60	19	discovery	discovery	NOUN
fnp-6285	60	20	of	of	ADP
fnp-6285	60	21	a	a	DET
fnp-6285	60	22	new	new	ADJ
fnp-6285	60	23	intracranial	intracranial	ADJ
fnp-6285	60	24	mpnst	mpnst	NOUN
fnp-6285	60	25	braf	braf	NOUN
fnp-6285	60	26	positive	positive	ADJ
fnp-6285	60	27	tumor	tumor	NOUN
fnp-6285	60	28	type	type	NOUN
fnp-6285	60	29	benoît	benoît	NOUN
fnp-6285	60	30	lhermitte1,2	lhermitte1,2	PROPN
fnp-6285	60	31	*	*	PROPN
fnp-6285	60	32	,	,	PUNCT
fnp-6285	60	33	thibaut	thibaut	PROPN
fnp-6285	60	34	wolf1,2	wolf1,2	PROPN
fnp-6285	60	35	*	*	PROPN
fnp-6285	60	36	,	,	PUNCT
fnp-6285	60	37	marlene	marlene	PROPN
fnp-6285	60	38	deschuyter2	deschuyter2	PROPN
fnp-6285	60	39	,	,	PUNCT
fnp-6285	60	40	damien	damien	PROPN
fnp-6285	60	41	reita2,4	reita2,4	PROPN
fnp-6285	60	42	,	,	PUNCT
fnp-6285	60	43	chinar	chinar	PROPN
fnp-6285	60	44	salmanli2	salmanli2	NOUN
fnp-6285	60	45	,	,	PUNCT
fnp-6285	60	46	agathe	agathe	PROPN
fnp-6285	60	47	chammas5	chammas5	PROPN
fnp-6285	60	48	,	,	PUNCT
fnp-6285	60	49	marie	marie	PROPN
fnp-6285	60	50	-	-	PUNCT
fnp-6285	60	51	pierre	pierre	PROPN
fnp-6285	60	52	chenard1,3	chenard1,3	PROPN
fnp-6285	60	53	,	,	PUNCT
fnp-6285	60	54	guillaume	guillaume	PROPN
fnp-6285	60	55	gauchotte6	gauchotte6	PROPN
fnp-6285	60	56	,	,	PUNCT
fnp-6285	60	57	stephanie	stephanie	PROPN
fnp-6285	60	58	lacomme7	lacomme7	PROPN
fnp-6285	60	59	,	,	PUNCT
fnp-6285	60	60	julien	julien	PROPN
fnp-6285	60	61	todeschi8	todeschi8	PROPN
fnp-6285	60	62	,	,	PUNCT
fnp-6285	60	63	andres	andres	PROPN
fnp-6285	60	64	coca8	coca8	PROPN
fnp-6285	60	65	,	,	PUNCT
fnp-6285	60	66	fabien	fabien	PROPN
fnp-6285	60	67	rech9	rech9	PROPN
fnp-6285	60	68	,	,	PUNCT
fnp-6285	60	69	romain	romain	PROPN
fnp-6285	60	70	appay10	appay10	ADJ
fnp-6285	60	71	,	,	PUNCT
fnp-6285	60	72	roland	roland	PROPN
fnp-6285	60	73	schott11	schott11	PROPN
fnp-6285	60	74	,	,	PUNCT
fnp-6285	60	75	georges	george	NOUN
fnp-6285	60	76	noel12	noel12	PROPN
fnp-6285	60	77	,	,	PUNCT
fnp-6285	60	78	sophie	sophie	PROPN
fnp-6285	60	79	martin2	martin2	PROPN
fnp-6285	60	80	,	,	PUNCT
fnp-6285	60	81	natacha	natacha	PROPN
fnp-6285	60	82	entz	entz	PROPN
fnp-6285	60	83	-	-	PUNCT
fnp-6285	60	84	werlé2,13	werlé2,13	PROPN
fnp-6285	60	85	department	department	NOUN
fnp-6285	60	86	of	of	ADP
fnp-6285	60	87	pathology	pathology	PROPN
fnp-6285	60	88	,	,	PUNCT
fnp-6285	60	89	university	university	NOUN
fnp-6285	60	90	hospitals	hospital	NOUN
fnp-6285	60	91	of	of	ADP
fnp-6285	60	92	strasbourg	strasbourg	NOUN
fnp-6285	60	93	,	,	PUNCT
fnp-6285	60	94	avenue	avenue	PROPN
fnp-6285	60	95	molière	molière	PROPN
fnp-6285	60	96	,	,	PUNCT
fnp-6285	60	97	67098	67098	NUM
fnp-6285	60	98	strasbourg	strasbourg	PROPN
fnp-6285	60	99	cedex	cedex	PROPN
fnp-6285	60	100	,	,	PUNCT
fnp-6285	60	101	france	france	PROPN
fnp-6285	60	102	umr	umr	PROPN
fnp-6285	60	103	cnrs	cnrs	PROPN
fnp-6285	60	104	7021	7021	NUM
fnp-6285	60	105	,	,	PUNCT
fnp-6285	60	106	laboratory	laboratory	NOUN
fnp-6285	60	107	bioimaging	bioimaging	NOUN
fnp-6285	60	108	and	and	CCONJ
fnp-6285	60	109	pathologies	pathology	NOUN
fnp-6285	60	110	,	,	PUNCT
fnp-6285	60	111	team	team	NOUN
fnp-6285	60	112	onko-3	onko-3	PROPN
fnp-6285	60	113	t	t	PROPN
fnp-6285	60	114	–	–	PUNCT
fnp-6285	60	115	translational	translational	ADJ
fnp-6285	60	116	,	,	PUNCT
fnp-6285	60	117	transversal	transversal	ADJ
fnp-6285	60	118	and	and	CCONJ
fnp-6285	60	119	therapeutic	therapeutic	ADJ
fnp-6285	60	120	oncology	oncology	NOUN
fnp-6285	60	121	,	,	PUNCT
fnp-6285	60	122	university	university	NOUN
fnp-6285	60	123	of	of	ADP
fnp-6285	60	124	strasbourg	strasbourg	PROPN
fnp-6285	60	125	university	university	PROPN
fnp-6285	60	126	,	,	PUNCT
fnp-6285	60	127	faculty	faculty	NOUN
fnp-6285	60	128	of	of	ADP
fnp-6285	60	129	pharmacy	pharmacy	NOUN
fnp-6285	60	130	,	,	PUNCT
fnp-6285	60	131	74	74	NUM
fnp-6285	60	132	route	route	NOUN
fnp-6285	60	133	du	du	PROPN
fnp-6285	60	134	rhin	rhin	PROPN
fnp-6285	60	135	,	,	PUNCT
fnp-6285	60	136	67405	67405	NUM
fnp-6285	60	137	,	,	PUNCT
fnp-6285	60	138	illkirch	illkirch	PROPN
fnp-6285	60	139	,	,	PUNCT
fnp-6285	60	140	france	france	PROPN
fnp-6285	60	141	centre	centre	PROPN
fnp-6285	60	142	de	de	X
fnp-6285	60	143	ressources	ressource	NOUN
fnp-6285	60	144	biologiques	biologique	NOUN
fnp-6285	60	145	,	,	PUNCT
fnp-6285	60	146	university	university	NOUN
fnp-6285	60	147	hospitals	hospital	NOUN
fnp-6285	60	148	of	of	ADP
fnp-6285	60	149	strasbourg	strasbourg	NOUN
fnp-6285	60	150	,	,	PUNCT
fnp-6285	60	151	avenue	avenue	PROPN
fnp-6285	60	152	molière	molière	PROPN
fnp-6285	60	153	,	,	PUNCT
fnp-6285	60	154	67098	67098	NUM
fnp-6285	60	155	strasbourg	strasbourg	PROPN
fnp-6285	60	156	cedex	cedex	PROPN
fnp-6285	60	157	,	,	PUNCT
fnp-6285	60	158	france	france	PROPN
fnp-6285	60	159	department	department	PROPN
fnp-6285	60	160	of	of	ADP
fnp-6285	60	161	cancer	cancer	PROPN
fnp-6285	60	162	molecular	molecular	ADJ
fnp-6285	60	163	genetics	genetic	NOUN
fnp-6285	60	164	laboratory	laboratory	NOUN
fnp-6285	60	165	of	of	ADP
fnp-6285	60	166	biochemistry	biochemistry	NOUN
fnp-6285	60	167	and	and	CCONJ
fnp-6285	60	168	molecular	molecular	ADJ
fnp-6285	60	169	biology	biology	NOUN
fnp-6285	60	170	,	,	PUNCT
fnp-6285	60	171	university	university	NOUN
fnp-6285	60	172	hospitals	hospital	NOUN
fnp-6285	60	173	of	of	ADP
fnp-6285	60	174	strasbourg	strasbourg	NOUN
fnp-6285	60	175	,	,	PUNCT
fnp-6285	60	176	france	france	PROPN
fnp-6285	60	177	department	department	PROPN
fnp-6285	60	178	of	of	ADP
fnp-6285	60	179	pediatric	pediatric	ADJ
fnp-6285	60	180	radiology	radiology	NOUN
fnp-6285	60	181	,	,	PUNCT
fnp-6285	60	182	university	university	NOUN
fnp-6285	60	183	hospitals	hospital	NOUN
fnp-6285	60	184	of	of	ADP
fnp-6285	60	185	strasbourg	strasbourg	NOUN
fnp-6285	60	186	,	,	PUNCT
fnp-6285	60	187	avenue	avenue	PROPN
fnp-6285	60	188	molière	molière	PROPN
fnp-6285	60	189	,	,	PUNCT
fnp-6285	60	190	67098	67098	NUM
fnp-6285	60	191	strasbourg	strasbourg	PROPN
fnp-6285	60	192	cedex	cedex	PROPN
fnp-6285	60	193	,	,	PUNCT
fnp-6285	60	194	france	france	PROPN
fnp-6285	60	195	department	department	PROPN
fnp-6285	60	196	of	of	ADP
fnp-6285	60	197	biopathology	biopathology	PROPN
fnp-6285	60	198	,	,	PUNCT
fnp-6285	60	199	chru	chru	PROPN
fnp-6285	60	200	nancy	nancy	PROPN
fnp-6285	60	201	,	,	PUNCT
fnp-6285	60	202	université	université	PROPN
fnp-6285	60	203	de	de	PROPN
fnp-6285	60	204	lorraine	lorraine	PROPN
fnp-6285	60	205	,	,	PUNCT
fnp-6285	60	206	inserm	inserm	PROPN
fnp-6285	60	207	u1256	u1256	PROPN
fnp-6285	60	208	,	,	PUNCT
fnp-6285	60	209	ngere	ngere	PROPN
fnp-6285	60	210	,	,	PUNCT
fnp-6285	60	211	f-54500	f-54500	PROPN
fnp-6285	60	212	vandoeuvre	vandoeuvre	PROPN
fnp-6285	60	213	-	-	PUNCT
fnp-6285	60	214	lès	lès	NOUN
fnp-6285	60	215	-	-	PUNCT
fnp-6285	60	216	nancy	nancy	PROPN
fnp-6285	60	217	,	,	PUNCT
fnp-6285	60	218	france	france	PROPN
fnp-6285	60	219	centre	centre	PROPN
fnp-6285	60	220	de	de	X
fnp-6285	60	221	ressources	ressource	NOUN
fnp-6285	60	222	biologiques	biologique	NOUN
fnp-6285	60	223	,	,	PUNCT
fnp-6285	60	224	bb-0033	bb-0033	NOUN
fnp-6285	60	225	-	-	PUNCT
fnp-6285	60	226	00035	00035	NUM
fnp-6285	60	227	,	,	PUNCT
fnp-6285	60	228	chru	chru	PROPN
fnp-6285	60	229	nancy	nancy	PROPN
fnp-6285	60	230	,	,	PUNCT
fnp-6285	60	231	f-54500	f-54500	PROPN
fnp-6285	60	232	vandoeuvre	vandoeuvre	PROPN
fnp-6285	60	233	-	-	PUNCT
fnp-6285	60	234	lès	lès	NOUN
fnp-6285	60	235	-	-	PUNCT
fnp-6285	60	236	nancy	nancy	PROPN
fnp-6285	60	237	,	,	PUNCT
fnp-6285	60	238	france	france	PROPN
fnp-6285	60	239	neurosurgery	neurosurgery	PROPN
fnp-6285	60	240	department	department	PROPN
fnp-6285	60	241	,	,	PUNCT
fnp-6285	60	242	university	university	NOUN
fnp-6285	60	243	hospital	hospital	NOUN
fnp-6285	60	244	of	of	ADP
fnp-6285	60	245	strasbourg	strasbourg	NOUN
fnp-6285	60	246	,	,	PUNCT
fnp-6285	60	247	67098	67098	NUM
fnp-6285	60	248	strasbourg	strasbourg	NOUN
fnp-6285	60	249	,	,	PUNCT
fnp-6285	60	250	france	france	PROPN
fnp-6285	60	251	department	department	PROPN
fnp-6285	60	252	of	of	ADP
fnp-6285	60	253	neurosurgery	neurosurgery	NOUN
fnp-6285	60	254	,	,	PUNCT
fnp-6285	60	255	chru	chru	NOUN
fnp-6285	60	256	-	-	PUNCT
fnp-6285	60	257	nancy	nancy	PROPN
fnp-6285	60	258	,	,	PUNCT
fnp-6285	60	259	université	université	PROPN
fnp-6285	60	260	de	de	PROPN
fnp-6285	60	261	lorraine	lorraine	PROPN
fnp-6285	60	262	,	,	PUNCT
fnp-6285	60	263	nancy	nancy	PROPN
fnp-6285	60	264	,	,	PUNCT
fnp-6285	60	265	france	france	PROPN
fnp-6285	60	266	department	department	PROPN
fnp-6285	60	267	of	of	ADP
fnp-6285	60	268	pathology	pathology	PROPN
fnp-6285	60	269	and	and	CCONJ
fnp-6285	60	270	neuropathology	neuropathology	NOUN
fnp-6285	60	271	,	,	PUNCT
fnp-6285	60	272	university	university	NOUN
fnp-6285	60	273	hospital	hospital	NOUN
fnp-6285	60	274	of	of	ADP
fnp-6285	60	275	timone	timone	ADJ
fnp-6285	60	276	marseille	marseille	NOUN
fnp-6285	60	277	,	,	PUNCT
fnp-6285	60	278	264	264	NUM
fnp-6285	60	279	rue	rue	X
fnp-6285	60	280	saint	saint	NOUN
fnp-6285	60	281	-	-	PUNCT
fnp-6285	60	282	pierre	pierre	NOUN
fnp-6285	60	283	,	,	PUNCT
fnp-6285	60	284	13005	13005	NUM
fnp-6285	60	285	,	,	PUNCT
fnp-6285	60	286	marseille	marseille	NOUN
fnp-6285	60	287	,	,	PUNCT
fnp-6285	60	288	france	france	PROPN
fnp-6285	60	289	oncology	oncology	PROPN
fnp-6285	60	290	department	department	PROPN
fnp-6285	60	291	,	,	PUNCT
fnp-6285	60	292	icans	ican	NOUN
fnp-6285	60	293	(	(	PUNCT
fnp-6285	60	294	institut	institut	PROPN
fnp-6285	60	295	de	de	PROPN
fnp-6285	60	296	cancérologie	cancérologie	PROPN
fnp-6285	60	297	strasbourg	strasbourg	PROPN
fnp-6285	60	298	europe	europe	PROPN
fnp-6285	60	299	)	)	PUNCT
fnp-6285	60	300	,	,	PUNCT
fnp-6285	60	301	17	17	NUM
fnp-6285	60	302	rue	rue	PROPN
fnp-6285	60	303	albert	albert	PROPN
fnp-6285	60	304	calmette	calmette	PROPN
fnp-6285	60	305	,	,	PUNCT
fnp-6285	60	306	67200	67200	NUM
fnp-6285	60	307	,	,	PUNCT
fnp-6285	60	308	strasbourg	strasbourg	NOUN
fnp-6285	60	309	,	,	PUNCT
fnp-6285	60	310	france	france	PROPN
fnp-6285	60	311	radiotherapy	radiotherapy	PROPN
fnp-6285	60	312	department	department	PROPN
fnp-6285	60	313	,	,	PUNCT
fnp-6285	60	314	icans	ican	NOUN
fnp-6285	60	315	(	(	PUNCT
fnp-6285	60	316	institut	institut	PROPN
fnp-6285	60	317	de	de	PROPN
fnp-6285	60	318	cancérologie	cancérologie	PROPN
fnp-6285	60	319	strasbourg	strasbourg	PROPN
fnp-6285	60	320	europe	europe	PROPN
fnp-6285	60	321	)	)	PUNCT
fnp-6285	60	322	,	,	PUNCT
fnp-6285	60	323	17	17	NUM
fnp-6285	60	324	rue	rue	PROPN
fnp-6285	60	325	albert	albert	PROPN
fnp-6285	60	326	calmette	calmette	PROPN
fnp-6285	60	327	,	,	PUNCT
fnp-6285	60	328	67200	67200	NUM
fnp-6285	60	329	,	,	PUNCT
fnp-6285	60	330	strasbourg	strasbourg	NOUN
fnp-6285	60	331	,	,	PUNCT
fnp-6285	60	332	france	france	PROPN
fnp-6285	60	333	pediatric	pediatric	ADJ
fnp-6285	60	334	onco	onco	NOUN
fnp-6285	60	335	-	-	PUNCT
fnp-6285	60	336	hematology	hematology	NOUN
fnp-6285	60	337	unit	unit	NOUN
fnp-6285	60	338	,	,	PUNCT
fnp-6285	60	339	university	university	NOUN
fnp-6285	60	340	hospitals	hospital	NOUN
fnp-6285	60	341	of	of	ADP
fnp-6285	60	342	strasbourg	strasbourg	NOUN
fnp-6285	60	343	,	,	PUNCT
fnp-6285	60	344	avenue	avenue	PROPN
fnp-6285	60	345	molière	molière	PROPN
fnp-6285	60	346	,	,	PUNCT
fnp-6285	60	347	67098	67098	NUM
fnp-6285	60	348	strasbourg	strasbourg	PROPN
fnp-6285	60	349	cedex	cedex	PROPN
fnp-6285	60	350	,	,	PUNCT
fnp-6285	60	351	france	france	PROPN
fnp-6285	60	352	*	*	PUNCT
fnp-6285	60	353	these	these	DET
fnp-6285	60	354	authors	author	NOUN
fnp-6285	60	355	share	share	VERB
fnp-6285	60	356	senior	senior	ADJ
fnp-6285	60	357	authorship	authorship	NOUN
fnp-6285	60	358	braf	braf	NOUN
fnp-6285	60	359	mutant	mutant	ADJ
fnp-6285	60	360	high	high	ADJ
fnp-6285	60	361	-	-	PUNCT
fnp-6285	60	362	grade	grade	NOUN
fnp-6285	60	363	gliomas	glioma	NOUN
fnp-6285	60	364	encompasses	encompass	VERB
fnp-6285	60	365	pxa	pxa	NOUN
fnp-6285	60	366	who	who	PRON
fnp-6285	60	367	grade	grade	VERB
fnp-6285	60	368	3	3	NUM
fnp-6285	60	369	,	,	PUNCT
fnp-6285	60	370	gbm	gbm	NOUN
fnp-6285	60	371	idh	idh	NOUN
fnp-6285	60	372	wt	wt	NOUN
fnp-6285	60	373	and	and	CCONJ
fnp-6285	60	374	hgap	hgap	NOUN
fnp-6285	60	375	.	.	PUNCT
fnp-6285	61	1	they	they	PRON
fnp-6285	61	2	share	share	VERB
fnp-6285	61	3	many	many	ADJ
fnp-6285	61	4	histomolecular	histomolecular	ADJ
fnp-6285	61	5	features	feature	NOUN
fnp-6285	61	6	making	make	VERB
fnp-6285	61	7	differential	differential	ADJ
fnp-6285	61	8	diagnosis	diagnosis	NOUN
fnp-6285	61	9	difficult	difficult	ADJ
fnp-6285	61	10	.	.	PUNCT
fnp-6285	62	1	dna	dna	PROPN
fnp-6285	62	2	methylation	methylation	NOUN
fnp-6285	62	3	profiling	profiling	NOUN
fnp-6285	62	4	is	be	AUX
fnp-6285	62	5	useful	useful	ADJ
fnp-6285	62	6	but	but	CCONJ
fnp-6285	62	7	some	some	DET
fnp-6285	62	8	tumors	tumor	NOUN
fnp-6285	62	9	fail	fail	VERB
fnp-6285	62	10	to	to	PART
fnp-6285	62	11	fall	fall	VERB
fnp-6285	62	12	in	in	ADP
fnp-6285	62	13	any	any	DET
fnp-6285	62	14	methylation	methylation	NOUN
fnp-6285	62	15	class	class	NOUN
fnp-6285	62	16	(	(	PUNCT
fnp-6285	62	17	mc	mc	PROPN
fnp-6285	62	18	)	)	PUNCT
fnp-6285	62	19	.	.	PUNCT
fnp-6285	63	1	we	we	PRON
fnp-6285	63	2	describe	describe	VERB
fnp-6285	63	3	a	a	DET
fnp-6285	63	4	cohort	cohort	NOUN
fnp-6285	63	5	of	of	ADP
fnp-6285	63	6	16	16	NUM
fnp-6285	63	7	intracranial	intracranial	ADJ
fnp-6285	63	8	braf	braf	NOUN
fnp-6285	63	9	-	-	PUNCT
fnp-6285	63	10	altered	alter	VERB
fnp-6285	63	11	tumors	tumor	NOUN
fnp-6285	63	12	with	with	ADP
fnp-6285	63	13	histological	histological	ADJ
fnp-6285	63	14	signs	sign	NOUN
fnp-6285	63	15	of	of	ADP
fnp-6285	63	16	malignancy	malignancy	NOUN
fnp-6285	63	17	.	.	PUNCT
fnp-6285	64	1	clinico	clinico	NOUN
fnp-6285	64	2	-	-	PUNCT
fnp-6285	64	3	radiological	radiological	ADJ
fnp-6285	64	4	,	,	PUNCT
fnp-6285	64	5	morphological	morphological	ADJ
fnp-6285	64	6	,	,	PUNCT
fnp-6285	64	7	genetic	genetic	ADJ
fnp-6285	64	8	,	,	PUNCT
fnp-6285	64	9	epigenetic	epigenetic	ADJ
fnp-6285	64	10	and	and	CCONJ
fnp-6285	64	11	trancriptomic	trancriptomic	ADJ
fnp-6285	64	12	features	feature	NOUN
fnp-6285	64	13	are	be	AUX
fnp-6285	64	14	comprehensively	comprehensively	ADV
fnp-6285	64	15	described	describe	VERB
fnp-6285	64	16	.	.	PUNCT
fnp-6285	65	1	if	if	SCONJ
fnp-6285	65	2	already	already	ADV
fnp-6285	65	3	known	know	VERB
fnp-6285	65	4	concomitant	concomitant	ADJ
fnp-6285	65	5	molecular	molecular	ADJ
fnp-6285	65	6	alterations	alteration	NOUN
fnp-6285	65	7	were	be	AUX
fnp-6285	65	8	frequently	frequently	ADV
fnp-6285	65	9	encountered	encounter	VERB
fnp-6285	65	10	,	,	PUNCT
fnp-6285	65	11	methylation	methylation	NOUN
fnp-6285	65	12	profiles	profile	NOUN
fnp-6285	65	13	seems	seem	VERB
fnp-6285	65	14	more	more	ADV
fnp-6285	65	15	diverse	diverse	ADJ
fnp-6285	65	16	than	than	SCONJ
fnp-6285	65	17	expected	expect	VERB
fnp-6285	65	18	.	.	PUNCT
fnp-6285	66	1	indeed	indeed	ADV
fnp-6285	66	2	,	,	PUNCT
fnp-6285	66	3	2	2	NUM
fnp-6285	66	4	cases	case	NOUN
fnp-6285	66	5	were	be	AUX
fnp-6285	66	6	assigned	assign	VERB
fnp-6285	66	7	to	to	ADP
fnp-6285	66	8	the	the	DET
fnp-6285	66	9	mpnst	mpnst	PROPN
fnp-6285	66	10	mc	mc	PROPN
fnp-6285	66	11	.	.	PUNCT
fnp-6285	67	1	these	these	DET
fnp-6285	67	2	cases	case	NOUN
fnp-6285	67	3	clustered	cluster	VERB
fnp-6285	67	4	in	in	ADP
fnp-6285	67	5	a	a	DET
fnp-6285	67	6	combined	combine	VERB
fnp-6285	67	7	t	t	PROPN
fnp-6285	67	8	-	-	PUNCT
fnp-6285	67	9	sne	sne	NOUN
fnp-6285	67	10	mixing	mix	VERB
fnp-6285	67	11	cns	cns	NOUN
fnp-6285	67	12	and	and	CCONJ
fnp-6285	67	13	sarcoma	sarcoma	PROPN
fnp-6285	67	14	mc	mc	PROPN
fnp-6285	67	15	in	in	ADP
fnp-6285	67	16	a	a	DET
fnp-6285	67	17	separate	separate	ADJ
fnp-6285	67	18	group	group	NOUN
fnp-6285	67	19	of	of	ADP
fnp-6285	67	20	high	high	ADJ
fnp-6285	67	21	-	-	PUNCT
fnp-6285	67	22	grade	grade	NOUN
fnp-6285	67	23	gliomas	glioma	NOUN
fnp-6285	67	24	located	locate	VERB
fnp-6285	67	25	in	in	ADP
fnp-6285	67	26	the	the	DET
fnp-6285	67	27	vicinity	vicinity	NOUN
fnp-6285	67	28	of	of	ADP
fnp-6285	67	29	the	the	DET
fnp-6285	67	30	mpnst	mpnst	NOUN
fnp-6285	67	31	-	-	PUNCT
fnp-6285	67	32	like	like	ADJ
fnp-6285	67	33	cluster	cluster	NOUN
fnp-6285	67	34	.	.	PUNCT
fnp-6285	68	1	transcriptomic	transcriptomic	ADJ
fnp-6285	68	2	data	datum	NOUN
fnp-6285	68	3	of	of	ADP
fnp-6285	68	4	these	these	DET
fnp-6285	68	5	tumors	tumor	NOUN
fnp-6285	68	6	also	also	ADV
fnp-6285	68	7	showed	show	VERB
fnp-6285	68	8	differences	difference	NOUN
fnp-6285	68	9	.	.	PUNCT
fnp-6285	69	1	these	these	DET
fnp-6285	69	2	data	datum	NOUN
fnp-6285	69	3	suggest	suggest	VERB
fnp-6285	69	4	the	the	DET
fnp-6285	69	5	existence	existence	NOUN
fnp-6285	69	6	of	of	ADP
fnp-6285	69	7	an	an	DET
fnp-6285	69	8	intracranial	intracranial	ADJ
fnp-6285	69	9	tumor	tumor	NOUN
fnp-6285	69	10	type	type	NOUN
fnp-6285	69	11	epigenetically	epigenetically	ADV
fnp-6285	69	12	and	and	CCONJ
fnp-6285	69	13	transcriptonomically	transcriptonomically	ADV
fnp-6285	69	14	close	close	ADJ
fnp-6285	69	15	to	to	ADP
fnp-6285	69	16	mpnst	mpnst	VERB
fnp-6285	69	17	whose	whose	DET
fnp-6285	69	18	frequency	frequency	NOUN
fnp-6285	69	19	and	and	CCONJ
fnp-6285	69	20	prognosis	prognosis	NOUN
fnp-6285	69	21	should	should	AUX
fnp-6285	69	22	be	be	AUX
fnp-6285	69	23	clarified	clarify	VERB
fnp-6285	69	24	in	in	ADP
fnp-6285	69	25	larger	large	ADJ
fnp-6285	69	26	series	series	NOUN
fnp-6285	69	27	.	.	PUNCT
fnp-6285	69	28	  	  	SPACE
fnp-6285	70	1	free	free	ADJ
fnp-6285	70	2	neuropathol	neuropathol	NOUN
fnp-6285	70	3	6:2:13	6:2:13	NUM
fnp-6285	70	4	high	high	ADJ
fnp-6285	70	5	level	level	NOUN
fnp-6285	70	6	of	of	ADP
fnp-6285	70	7	cdkn2a	cdkn2a	ADJ
fnp-6285	70	8	homozygous	homozygous	ADJ
fnp-6285	70	9	deletion	deletion	NOUN
fnp-6285	70	10	discrepancies	discrepancy	NOUN
fnp-6285	70	11	between	between	ADP
fnp-6285	70	12	fluorescent	fluorescent	NOUN
fnp-6285	70	13	in	in	ADP
fnp-6285	70	14	situ	situ	ADJ
fnp-6285	70	15	hybridization	hybridization	NOUN
fnp-6285	70	16	and	and	CCONJ
fnp-6285	70	17	dna	dna	PROPN
fnp-6285	70	18	methylation	methylation	NOUN
fnp-6285	70	19	-	-	PUNCT
fnp-6285	70	20	derived	derive	VERB
fnp-6285	70	21	copy	copy	NOUN
fnp-6285	70	22	number	number	NOUN
fnp-6285	70	23	in	in	ADP
fnp-6285	70	24	a	a	DET
fnp-6285	70	25	braf	braf	NOUN
fnp-6285	70	26	-	-	PUNCT
fnp-6285	70	27	mutant	mutant	NOUN
fnp-6285	70	28	glioma	glioma	NOUN
fnp-6285	70	29	cohort	cohort	NOUN
fnp-6285	70	30	how	how	SCONJ
fnp-6285	70	31	to	to	PART
fnp-6285	70	32	solve	solve	VERB
fnp-6285	70	33	the	the	DET
fnp-6285	70	34	dilemma	dilemma	NOUN
fnp-6285	70	35	?	?	PUNCT
fnp-6285	71	1	thibaut	thibaut	PROPN
fnp-6285	71	2	wolf1	wolf1	PROPN
fnp-6285	71	3	,	,	PUNCT
fnp-6285	71	4	 	 	SPACE
fnp-6285	71	5	damien	damien	PROPN
fnp-6285	71	6	reita2,3	reita2,3	PROPN
fnp-6285	71	7	,	,	PUNCT
fnp-6285	71	8	marlène	marlène	ADJ
fnp-6285	71	9	deschuyter3	deschuyter3	PROPN
fnp-6285	71	10	,	,	PUNCT
fnp-6285	71	11	julie	julie	PROPN
fnp-6285	71	12	buffa2	buffa2	PROPN
fnp-6285	71	13	,	,	PUNCT
fnp-6285	71	14	erwan	erwan	PROPN
fnp-6285	71	15	pencreach2	pencreach2	PROPN
fnp-6285	71	16	,	,	PUNCT
fnp-6285	71	17	 	 	SPACE
fnp-6285	71	18	eric	eric	PROPN
fnp-6285	71	19	jeandidier4	jeandidier4	PROPN
fnp-6285	71	20	,	,	PUNCT
fnp-6285	71	21	marie	marie	PROPN
fnp-6285	71	22	-	-	PUNCT
fnp-6285	71	23	pierre	pierre	PROPN
fnp-6285	71	24	chenard1	chenard1	NOUN
fnp-6285	71	25	,	,	PUNCT
fnp-6285	71	26	natacha	natacha	PROPN
fnp-6285	71	27	entz	entz	PROPN
fnp-6285	71	28	-	-	PUNCT
fnp-6285	71	29	werlé3–5,benoît	werlé3–5,benoît	PROPN
fnp-6285	71	30	lhermitte1,3	lhermitte1,3	PROPN
fnp-6285	71	31	pathology	pathology	PROPN
fnp-6285	71	32	department	department	PROPN
fnp-6285	71	33	,	,	PUNCT
fnp-6285	71	34	university	university	NOUN
fnp-6285	71	35	hospital	hospital	NOUN
fnp-6285	71	36	of	of	ADP
fnp-6285	71	37	strasbourg	strasbourg	NOUN
fnp-6285	71	38	,	,	PUNCT
fnp-6285	71	39	67098	67098	NUM
fnp-6285	71	40	strasbourg	strasbourg	NOUN
fnp-6285	71	41	,	,	PUNCT
fnp-6285	71	42	france	france	PROPN
fnp-6285	71	43	oncobiology	oncobiology	NOUN
fnp-6285	71	44	platform	platform	NOUN
fnp-6285	71	45	,	,	PUNCT
fnp-6285	71	46	laboratory	laboratory	NOUN
fnp-6285	71	47	of	of	ADP
fnp-6285	71	48	biochemistry	biochemistry	NOUN
fnp-6285	71	49	,	,	PUNCT
fnp-6285	71	50	university	university	NOUN
fnp-6285	71	51	hospital	hospital	NOUN
fnp-6285	71	52	of	of	ADP
fnp-6285	71	53	strasbourg	strasbourg	NOUN
fnp-6285	71	54	,	,	PUNCT
fnp-6285	71	55	67098	67098	NUM
fnp-6285	71	56	strasbourg	strasbourg	NOUN
fnp-6285	71	57	,	,	PUNCT
fnp-6285	71	58	france	france	PROPN
fnp-6285	71	59	umr	umr	PROPN
fnp-6285	71	60	cnrs	cnrs	PROPN
fnp-6285	71	61	7021	7021	NUM
fnp-6285	71	62	,	,	PUNCT
fnp-6285	71	63	laboratory	laboratory	NOUN
fnp-6285	71	64	bioimaging	bioimaging	NOUN
fnp-6285	71	65	and	and	CCONJ
fnp-6285	71	66	pathologies	pathology	NOUN
fnp-6285	71	67	,	,	PUNCT
fnp-6285	71	68	onko3	onko3	PROPN
fnp-6285	71	69	t	t	PROPN
fnp-6285	71	70	team	team	NOUN
fnp-6285	71	71	,	,	PUNCT
fnp-6285	71	72	faculty	faculty	NOUN
fnp-6285	71	73	of	of	ADP
fnp-6285	71	74	pharmacy	pharmacy	NOUN
fnp-6285	71	75	,	,	PUNCT
fnp-6285	71	76	67401	67401	NUM
fnp-6285	71	77	illkirch	illkirch	NOUN
fnp-6285	71	78	,	,	PUNCT
fnp-6285	71	79	france	france	PROPN
fnp-6285	71	80	cytogenetic	cytogenetic	ADJ
fnp-6285	71	81	departement	departement	NOUN
fnp-6285	71	82	,	,	PUNCT
fnp-6285	71	83	mulhouse	mulhouse	NOUN
fnp-6285	71	84	hospital	hospital	NOUN
fnp-6285	71	85	,	,	PUNCT
fnp-6285	71	86	68100	68100	NUM
fnp-6285	71	87	mulhouse	mulhouse	NOUN
fnp-6285	71	88	,	,	PUNCT
fnp-6285	71	89	france	france	PROPN
fnp-6285	71	90	pediatric	pediatric	ADJ
fnp-6285	71	91	oncology	oncology	NOUN
fnp-6285	71	92	department	department	PROPN
fnp-6285	71	93	,	,	PUNCT
fnp-6285	71	94	university	university	NOUN
fnp-6285	71	95	hospital	hospital	NOUN
fnp-6285	71	96	of	of	ADP
fnp-6285	71	97	strasbourg	strasbourg	NOUN
fnp-6285	71	98	,	,	PUNCT
fnp-6285	71	99	67098	67098	NUM
fnp-6285	71	100	strasbourg	strasbourg	NOUN
fnp-6285	71	101	,	,	PUNCT
fnp-6285	71	102	france	france	PROPN
fnp-6285	71	103	clarifying	clarify	VERB
fnp-6285	71	104	the	the	DET
fnp-6285	71	105	diagnosis	diagnosis	NOUN
fnp-6285	71	106	and	and	CCONJ
fnp-6285	71	107	prognosis	prognosis	NOUN
fnp-6285	71	108	of	of	ADP
fnp-6285	71	109	braf	braf	NOUN
fnp-6285	71	110	-	-	PUNCT
fnp-6285	71	111	mutant	mutant	ADJ
fnp-6285	71	112	gliomas	glioma	NOUN
fnp-6285	71	113	requires	require	VERB
fnp-6285	71	114	testing	test	VERB
fnp-6285	71	115	for	for	ADP
fnp-6285	71	116	cdkn2a	cdkn2a	ADJ
fnp-6285	71	117	homozygous	homozygous	ADJ
fnp-6285	71	118	deletion	deletion	NOUN
fnp-6285	71	119	(	(	PUNCT
fnp-6285	71	120	hd	hd	NOUN
fnp-6285	71	121	)	)	PUNCT
fnp-6285	71	122	.	.	PUNCT
fnp-6285	72	1	we	we	PRON
fnp-6285	72	2	herein	herein	VERB
fnp-6285	72	3	compare	compare	VERB
fnp-6285	72	4	the	the	DET
fnp-6285	72	5	performances	performance	NOUN
fnp-6285	72	6	of	of	ADP
fnp-6285	72	7	5	5	NUM
fnp-6285	72	8	different	different	ADJ
fnp-6285	72	9	techniques	technique	NOUN
fnp-6285	72	10	currently	currently	ADV
fnp-6285	72	11	available	available	ADJ
fnp-6285	72	12	to	to	PART
fnp-6285	72	13	detect	detect	VERB
fnp-6285	72	14	it	it	PRON
fnp-6285	72	15	on	on	ADP
fnp-6285	72	16	a	a	DET
fnp-6285	72	17	retrospective	retrospective	ADJ
fnp-6285	72	18	cohort	cohort	NOUN
fnp-6285	72	19	of	of	ADP
fnp-6285	72	20	20	20	NUM
fnp-6285	72	21	braf	braf	NOUN
fnp-6285	72	22	-	-	PUNCT
fnp-6285	72	23	altered	alter	VERB
fnp-6285	72	24	gliomas	glioma	NOUN
fnp-6285	72	25	,	,	PUNCT
fnp-6285	72	26	including	include	VERB
fnp-6285	72	27	fish	fish	NOUN
fnp-6285	72	28	and	and	CCONJ
fnp-6285	72	29	dna	dna	PROPN
fnp-6285	72	30	methylation	methylation	NOUN
fnp-6285	72	31	-	-	PUNCT
fnp-6285	72	32	derived	derive	VERB
fnp-6285	72	33	cnv	cnv	NOUN
fnp-6285	72	34	.	.	PUNCT
fnp-6285	73	1	a	a	DET
fnp-6285	73	2	high	high	ADJ
fnp-6285	73	3	level	level	NOUN
fnp-6285	73	4	of	of	ADP
fnp-6285	73	5	cdkn2a	cdkn2a	PROPN
fnp-6285	73	6	hd	hd	NOUN
fnp-6285	73	7	detection	detection	NOUN
fnp-6285	73	8	discrepancy	discrepancy	NOUN
fnp-6285	73	9	was	be	AUX
fnp-6285	73	10	observed	observe	VERB
fnp-6285	73	11	,	,	PUNCT
fnp-6285	73	12	especially	especially	ADV
fnp-6285	73	13	between	between	ADP
fnp-6285	73	14	fish	fish	NOUN
fnp-6285	73	15	and	and	CCONJ
fnp-6285	73	16	other	other	ADJ
fnp-6285	73	17	techniques	technique	NOUN
fnp-6285	73	18	suggesting	suggest	VERB
fnp-6285	73	19	low	low	ADJ
fnp-6285	73	20	sensitivity	sensitivity	NOUN
fnp-6285	73	21	of	of	ADP
fnp-6285	73	22	fish	fish	NOUN
fnp-6285	73	23	.	.	PUNCT
fnp-6285	74	1	to	to	PART
fnp-6285	74	2	solve	solve	VERB
fnp-6285	74	3	the	the	DET
fnp-6285	74	4	dilemma	dilemma	NOUN
fnp-6285	74	5	,	,	PUNCT
fnp-6285	74	6	an	an	DET
fnp-6285	74	7	original	original	ADJ
fnp-6285	74	8	approach	approach	NOUN
fnp-6285	74	9	using	use	VERB
fnp-6285	74	10	genomic	genomic	ADJ
fnp-6285	74	11	alignment	alignment	NOUN
fnp-6285	74	12	of	of	ADP
fnp-6285	74	13	dna	dna	PROPN
fnp-6285	74	14	methylation	methylation	NOUN
fnp-6285	74	15	-	-	PUNCT
fnp-6285	74	16	derived	derive	VERB
fnp-6285	74	17	cnv	cnv	PROPN
fnp-6285	74	18	raw	raw	ADJ
fnp-6285	74	19	data	datum	NOUN
fnp-6285	74	20	was	be	AUX
fnp-6285	74	21	performed	perform	VERB
fnp-6285	74	22	.	.	PUNCT
fnp-6285	75	1	this	this	PRON
fnp-6285	75	2	revealed	reveal	VERB
fnp-6285	75	3	a	a	DET
fnp-6285	75	4	high	high	ADJ
fnp-6285	75	5	rate	rate	NOUN
fnp-6285	75	6	of	of	ADP
fnp-6285	75	7	isolated	isolated	ADJ
fnp-6285	75	8	cdkn2a	cdkn2a	PROPN
fnp-6285	75	9	hd	hd	NOUN
fnp-6285	75	10	excluding	exclude	VERB
fnp-6285	75	11	mtap	mtap	NOUN
fnp-6285	75	12	among	among	ADP
fnp-6285	75	13	fish	fish	NOUN
fnp-6285	75	14	false	false	ADJ
fnp-6285	75	15	negative	negative	ADJ
fnp-6285	75	16	cases	case	NOUN
fnp-6285	75	17	,	,	PUNCT
fnp-6285	75	18	owing	owe	VERB
fnp-6285	75	19	to	to	ADP
fnp-6285	75	20	non	non	ADJ
fnp-6285	75	21	-	-	ADJ
fnp-6285	75	22	specific	specific	ADJ
fnp-6285	75	23	hybridization	hybridization	NOUN
fnp-6285	75	24	of	of	ADP
fnp-6285	75	25	the	the	DET
fnp-6285	75	26	probe	probe	NOUN
fnp-6285	75	27	,	,	PUNCT
fnp-6285	75	28	which	which	PRON
fnp-6285	75	29	is	be	AUX
fnp-6285	75	30	a	a	DET
fnp-6285	75	31	very	very	ADV
fnp-6285	75	32	commonly	commonly	ADV
fnp-6285	75	33	used	use	VERB
fnp-6285	75	34	probe	probe	NOUN
fnp-6285	75	35	targeting	target	VERB
fnp-6285	75	36	the	the	DET
fnp-6285	75	37	entire	entire	ADJ
fnp-6285	75	38	9p21	9p21	NOUN
fnp-6285	75	39	region	region	NOUN
fnp-6285	75	40	including	include	VERB
fnp-6285	75	41	cdkn2a	cdkn2a	PROPN
fnp-6285	75	42	and	and	CCONJ
fnp-6285	75	43	mtap	mtap	ADJ
fnp-6285	75	44	.	.	PUNCT
fnp-6285	76	1	we	we	PRON
fnp-6285	76	2	therefore	therefore	ADV
fnp-6285	76	3	report	report	VERB
fnp-6285	76	4	a	a	DET
fnp-6285	76	5	molecular	molecular	ADJ
fnp-6285	76	6	proof	proof	NOUN
fnp-6285	76	7	of	of	ADP
fnp-6285	76	8	a	a	DET
fnp-6285	76	9	previously	previously	ADV
fnp-6285	76	10	suspected	suspect	VERB
fnp-6285	76	11	low	low	ADJ
fnp-6285	76	12	sensitivity	sensitivity	NOUN
fnp-6285	76	13	of	of	ADP
fnp-6285	76	14	fish	fish	NOUN
fnp-6285	76	15	assay	assay	VERB
fnp-6285	76	16	among	among	ADP
fnp-6285	76	17	braf	braf	NOUN
fnp-6285	76	18	-	-	PUNCT
fnp-6285	76	19	altered	alter	VERB
fnp-6285	76	20	gliomas	glioma	NOUN
fnp-6285	76	21	with	with	ADP
fnp-6285	76	22	an	an	DET
fnp-6285	76	23	original	original	ADJ
fnp-6285	76	24	bioinformatic	bioinformatic	ADJ
fnp-6285	76	25	pipeline	pipeline	NOUN
fnp-6285	76	26	based	base	VERB
fnp-6285	76	27	on	on	ADP
fnp-6285	76	28	dna	dna	PROPN
fnp-6285	76	29	methylation	methylation	NOUN
fnp-6285	76	30	raw	raw	ADJ
fnp-6285	76	31	data	datum	NOUN
fnp-6285	76	32	.	.	PUNCT
fnp-6285	76	33	  	  	SPACE
fnp-6285	77	1	free	free	ADJ
fnp-6285	77	2	neuropathol	neuropathol	NOUN
fnp-6285	77	3	6:2:14	6:2:14	NUM
fnp-6285	77	4	fgfr1	fgfr1	PROPN
fnp-6285	77	5	wild	wild	ADJ
fnp-6285	77	6	-	-	PUNCT
fnp-6285	77	7	type	type	NOUN
fnp-6285	77	8	rosette	rosette	NOUN
fnp-6285	77	9	-	-	PUNCT
fnp-6285	77	10	forming	form	VERB
fnp-6285	77	11	glioneuronal	glioneuronal	ADJ
fnp-6285	77	12	tumours	tumour	NOUN
fnp-6285	77	13	mégane	mégane	NOUN
fnp-6285	77	14	le	le	ADP
fnp-6285	77	15	quang1	quang1	PROPN
fnp-6285	77	16	,	,	PUNCT
fnp-6285	77	17	 	 	SPACE
fnp-6285	77	18	emmanuelle	emmanuelle	PROPN
fnp-6285	77	19	uro	uro	PROPN
fnp-6285	77	20	-	-	PUNCT
fnp-6285	77	21	coste2–4	coste2–4	PROPN
fnp-6285	77	22	pathology	pathology	NOUN
fnp-6285	77	23	department	department	PROPN
fnp-6285	77	24	,	,	PUNCT
fnp-6285	77	25	bordeaux	bordeaux	NOUN
fnp-6285	77	26	university	university	NOUN
fnp-6285	77	27	hospital	hospital	NOUN
fnp-6285	77	28	,	,	PUNCT
fnp-6285	77	29	bordeaux	bordeaux	NOUN
fnp-6285	77	30	,	,	PUNCT
fnp-6285	77	31	france	france	PROPN
fnp-6285	77	32	pathology	pathology	PROPN
fnp-6285	77	33	department	department	PROPN
fnp-6285	77	34	,	,	PUNCT
fnp-6285	77	35	toulouse	toulouse	NOUN
fnp-6285	77	36	university	university	NOUN
fnp-6285	77	37	hospital	hospital	NOUN
fnp-6285	77	38	,	,	PUNCT
fnp-6285	77	39	toulouse	toulouse	NOUN
fnp-6285	77	40	,	,	PUNCT
fnp-6285	77	41	france	france	PROPN
fnp-6285	77	42	inserm	inserm	NOUN
fnp-6285	77	43	u1037	u1037	PROPN
fnp-6285	77	44	,	,	PUNCT
fnp-6285	77	45	toulouse	toulouse	NOUN
fnp-6285	77	46	cancer	cancer	NOUN
fnp-6285	77	47	research	research	NOUN
fnp-6285	77	48	centre	centre	NOUN
fnp-6285	77	49	(	(	PUNCT
fnp-6285	77	50	crct	crct	PROPN
fnp-6285	77	51	)	)	PUNCT
fnp-6285	77	52	,	,	PUNCT
fnp-6285	77	53	toulouse	toulouse	NOUN
fnp-6285	77	54	,	,	PUNCT
fnp-6285	77	55	france	france	PROPN
fnp-6285	77	56	service	service	PROPN
fnp-6285	77	57	d'anatomie	d'anatomie	PROPN
fnp-6285	77	58	et	et	PROPN
fnp-6285	77	59	cytologie	cytologie	PROPN
fnp-6285	77	60	pathologiques	pathologique	NOUN
fnp-6285	77	61	,	,	PUNCT
fnp-6285	77	62	institut	institut	PROPN
fnp-6285	77	63	universitaire	universitaire	PROPN
fnp-6285	77	64	du	du	PROPN
fnp-6285	77	65	cancer	cancer	NOUN
fnp-6285	77	66	-	-	PUNCT
fnp-6285	77	67	oncopole	oncopole	NOUN
fnp-6285	77	68	,	,	PUNCT
fnp-6285	77	69	toulouse	toulouse	NOUN
fnp-6285	77	70	cedex	cedex	NOUN
fnp-6285	77	71	9	9	NUM
fnp-6285	77	72	,	,	PUNCT
fnp-6285	77	73	france	france	PROPN
fnp-6285	77	74	we	we	PRON
fnp-6285	77	75	report	report	VERB
fnp-6285	77	76	three	three	NUM
fnp-6285	77	77	cases	case	NOUN
fnp-6285	77	78	of	of	ADP
fnp-6285	77	79	rosette	rosette	NOUN
fnp-6285	77	80	-	-	PUNCT
fnp-6285	77	81	forming	form	VERB
fnp-6285	77	82	glioneuronal	glioneuronal	ADJ
fnp-6285	77	83	tumours	tumour	NOUN
fnp-6285	77	84	(	(	PUNCT
fnp-6285	77	85	rgnt	rgnt	NOUN
fnp-6285	77	86	)	)	PUNCT
fnp-6285	77	87	,	,	PUNCT
fnp-6285	77	88	diagnosed	diagnose	VERB
fnp-6285	77	89	through	through	ADP
fnp-6285	77	90	dna	dna	PROPN
fnp-6285	77	91	-	-	PUNCT
fnp-6285	77	92	methylation	methylation	NOUN
fnp-6285	77	93	profiling	profiling	NOUN
fnp-6285	77	94	,	,	PUNCT
fnp-6285	77	95	without	without	ADP
fnp-6285	77	96	the	the	DET
fnp-6285	77	97	classical	classical	ADJ
fnp-6285	77	98	fgfr1	fgfr1	NOUN
fnp-6285	77	99	alteration	alteration	NOUN
fnp-6285	77	100	commonly	commonly	ADV
fnp-6285	77	101	reported	report	VERB
fnp-6285	77	102	in	in	ADP
fnp-6285	77	103	this	this	DET
fnp-6285	77	104	entity	entity	NOUN
fnp-6285	77	105	.	.	PUNCT
fnp-6285	78	1	desirable	desirable	ADJ
fnp-6285	78	2	criteria	criterion	NOUN
fnp-6285	78	3	include	include	VERB
fnp-6285	78	4	the	the	DET
fnp-6285	78	5	presence	presence	NOUN
fnp-6285	78	6	of	of	ADP
fnp-6285	78	7	a	a	DET
fnp-6285	78	8	fgfr1	fgfr1	NOUN
fnp-6285	78	9	mutation	mutation	NOUN
fnp-6285	78	10	with	with	ADP
fnp-6285	78	11	coexisting	coexist	VERB
fnp-6285	78	12	pik3ca	pik3ca	NOUN
fnp-6285	78	13	and/or	and/or	CCONJ
fnp-6285	78	14	nf1	nf1	NOUN
fnp-6285	78	15	mutation	mutation	NOUN
fnp-6285	78	16	.	.	PUNCT
fnp-6285	79	1	several	several	ADJ
fnp-6285	79	2	teams	team	NOUN
fnp-6285	79	3	have	have	AUX
fnp-6285	79	4	reported	report	VERB
fnp-6285	79	5	the	the	DET
fnp-6285	79	6	constant	constant	ADJ
fnp-6285	79	7	presence	presence	NOUN
fnp-6285	79	8	of	of	ADP
fnp-6285	79	9	fgfr1	fgfr1	NOUN
fnp-6285	79	10	mutation	mutation	NOUN
fnp-6285	79	11	in	in	ADP
fnp-6285	79	12	their	their	PRON
fnp-6285	79	13	rgnt	rgnt	ADJ
fnp-6285	79	14	series	series	NOUN
fnp-6285	79	15	,	,	PUNCT
fnp-6285	79	16	suggesting	suggest	VERB
fnp-6285	79	17	that	that	SCONJ
fnp-6285	79	18	this	this	DET
fnp-6285	79	19	criterion	criterion	NOUN
fnp-6285	79	20	should	should	AUX
fnp-6285	79	21	appear	appear	VERB
fnp-6285	79	22	as	as	ADP
fnp-6285	79	23	essential	essential	ADJ
fnp-6285	79	24	in	in	ADP
fnp-6285	79	25	the	the	DET
fnp-6285	79	26	next	next	ADJ
fnp-6285	79	27	classification	classification	NOUN
fnp-6285	79	28	.	.	PUNCT
fnp-6285	80	1	nevertheless	nevertheless	ADV
fnp-6285	80	2	,	,	PUNCT
fnp-6285	80	3	our	our	PRON
fnp-6285	80	4	three	three	NUM
fnp-6285	80	5	cases	case	NOUN
fnp-6285	80	6	of	of	ADP
fnp-6285	80	7	rgnt	rgnt	NOUN
fnp-6285	80	8	show	show	NOUN
fnp-6285	80	9	that	that	SCONJ
fnp-6285	80	10	the	the	DET
fnp-6285	80	11	absence	absence	NOUN
fnp-6285	80	12	of	of	ADP
fnp-6285	80	13	fgfr1	fgfr1	NOUN
fnp-6285	80	14	alteration	alteration	NOUN
fnp-6285	80	15	does	do	AUX
fnp-6285	80	16	not	not	PART
fnp-6285	80	17	eliminate	eliminate	VERB
fnp-6285	80	18	this	this	DET
fnp-6285	80	19	diagnosis	diagnosis	NOUN
fnp-6285	80	20	.	.	PUNCT
fnp-6285	81	1	our	our	PRON
fnp-6285	81	2	finding	finding	NOUN
fnp-6285	81	3	is	be	AUX
fnp-6285	81	4	also	also	ADV
fnp-6285	81	5	important	important	ADJ
fnp-6285	81	6	from	from	ADP
fnp-6285	81	7	a	a	DET
fnp-6285	81	8	therapeutic	therapeutic	ADJ
fnp-6285	81	9	point	point	NOUN
fnp-6285	81	10	of	of	ADP
fnp-6285	81	11	view	view	NOUN
fnp-6285	81	12	since	since	SCONJ
fnp-6285	81	13	two	two	NUM
fnp-6285	81	14	of	of	ADP
fnp-6285	81	15	our	our	PRON
fnp-6285	81	16	cases	case	NOUN
fnp-6285	81	17	have	have	VERB
fnp-6285	81	18	genetic	genetic	ADJ
fnp-6285	81	19	alterations	alteration	NOUN
fnp-6285	81	20	likely	likely	ADJ
fnp-6285	81	21	to	to	PART
fnp-6285	81	22	be	be	AUX
fnp-6285	81	23	treated	treat	VERB
fnp-6285	81	24	by	by	ADP
fnp-6285	81	25	targeted	target	VERB
fnp-6285	81	26	therapy	therapy	NOUN
fnp-6285	81	27	:	:	PUNCT
fnp-6285	81	28	akt2	akt2	NOUN
fnp-6285	81	29	e17k	e17k	ADJ
fnp-6285	81	30	mutation	mutation	NOUN
fnp-6285	81	31	by	by	ADP
fnp-6285	81	32	akt	akt	PROPN
fnp-6285	81	33	inhibitors	inhibitor	NOUN
fnp-6285	81	34	currently	currently	ADV
fnp-6285	81	35	involved	involve	VERB
fnp-6285	81	36	in	in	ADP
fnp-6285	81	37	clinical	clinical	ADJ
fnp-6285	81	38	trials	trial	NOUN
fnp-6285	81	39	and	and	CCONJ
fnp-6285	81	40	kiff5::erbb4	kiff5::erbb4	VERB
fnp-6285	81	41	fusion	fusion	NOUN
fnp-6285	81	42	by	by	ADP
fnp-6285	81	43	second	second	ADJ
fnp-6285	81	44	-	-	PUNCT
fnp-6285	81	45	generation	generation	NOUN
fnp-6285	81	46	pan	pan	ADJ
fnp-6285	81	47	-	-	ADJ
fnp-6285	81	48	erbb	erbb	ADJ
fnp-6285	81	49	tyrosine	tyrosine	NOUN
fnp-6285	81	50	kinase	kinase	PROPN
fnp-6285	81	51	inhibitors	inhibitor	NOUN
fnp-6285	81	52	.	.	PUNCT
fnp-6285	81	53	  	  	SPACE
fnp-6285	82	1	free	free	ADJ
fnp-6285	82	2	neuropathol	neuropathol	NOUN
fnp-6285	82	3	6:2:15	6:2:15	NUM
fnp-6285	82	4	cerebral	cerebral	ADJ
fnp-6285	82	5	inflammation	inflammation	NOUN
fnp-6285	82	6	in	in	ADP
fnp-6285	82	7	a	a	DET
fnp-6285	82	8	patient	patient	NOUN
fnp-6285	82	9	with	with	ADP
fnp-6285	82	10	kabuki	kabuki	NOUN
fnp-6285	82	11	syndrome	syndrome	PROPN
fnp-6285	82	12	tommaso	tommaso	PROPN
fnp-6285	82	13	nicoletti1,2	nicoletti1,2	PROPN
fnp-6285	82	14	,	,	PUNCT
fnp-6285	82	15	magdeldin	magdeldin	PROPN
fnp-6285	82	16	elgizouli3	elgizouli3	PROPN
fnp-6285	82	17	,	,	PUNCT
fnp-6285	82	18	klaus	klaus	PROPN
fnp-6285	82	19	warnatz4,5	warnatz4,5	PROPN
fnp-6285	82	20	,	,	PUNCT
fnp-6285	82	21	patrick	patrick	PROPN
fnp-6285	82	22	roth1	roth1	PROPN
fnp-6285	82	23	,	,	PUNCT
fnp-6285	82	24	regina	regina	PROPN
fnp-6285	82	25	reimann6	reimann6	PROPN
fnp-6285	82	26	department	department	PROPN
fnp-6285	82	27	of	of	ADP
fnp-6285	82	28	neurology	neurology	NOUN
fnp-6285	82	29	,	,	PUNCT
fnp-6285	82	30	university	university	NOUN
fnp-6285	82	31	hospital	hospital	NOUN
fnp-6285	82	32	zurich	zurich	PROPN
fnp-6285	82	33	and	and	CCONJ
fnp-6285	82	34	university	university	PROPN
fnp-6285	82	35	of	of	ADP
fnp-6285	82	36	zurich	zurich	PROPN
fnp-6285	82	37	,	,	PUNCT
fnp-6285	82	38	zurich	zurich	PROPN
fnp-6285	82	39	,	,	PUNCT
fnp-6285	82	40	switzerland	switzerland	PROPN
fnp-6285	82	41	department	department	PROPN
fnp-6285	82	42	of	of	ADP
fnp-6285	82	43	neuropathology	neuropathology	NOUN
fnp-6285	82	44	,	,	PUNCT
fnp-6285	82	45	university	university	NOUN
fnp-6285	82	46	hospital	hospital	NOUN
fnp-6285	82	47	essen	essen	PROPN
fnp-6285	82	48	,	,	PUNCT
fnp-6285	82	49	essen	essen	PROPN
fnp-6285	82	50	,	,	PUNCT
fnp-6285	82	51	germany	germany	PROPN
fnp-6285	82	52	institute	institute	PROPN
fnp-6285	82	53	of	of	ADP
fnp-6285	82	54	medical	medical	ADJ
fnp-6285	82	55	genetics	genetic	NOUN
fnp-6285	82	56	,	,	PUNCT
fnp-6285	82	57	university	university	NOUN
fnp-6285	82	58	of	of	ADP
fnp-6285	82	59	zurich	zurich	PROPN
fnp-6285	82	60	,	,	PUNCT
fnp-6285	82	61	zurich	zurich	PROPN
fnp-6285	82	62	,	,	PUNCT
fnp-6285	82	63	switzerland	switzerland	PROPN
fnp-6285	82	64	department	department	PROPN
fnp-6285	82	65	of	of	ADP
fnp-6285	82	66	clinical	clinical	ADJ
fnp-6285	82	67	immunology	immunology	NOUN
fnp-6285	82	68	,	,	PUNCT
fnp-6285	82	69	university	university	NOUN
fnp-6285	82	70	hospital	hospital	NOUN
fnp-6285	82	71	zurich	zurich	PROPN
fnp-6285	82	72	,	,	PUNCT
fnp-6285	82	73	zurich	zurich	PROPN
fnp-6285	82	74	,	,	PUNCT
fnp-6285	82	75	switzerland	switzerland	PROPN
fnp-6285	82	76	department	department	PROPN
fnp-6285	82	77	of	of	ADP
fnp-6285	82	78	rheumatology	rheumatology	NOUN
fnp-6285	82	79	and	and	CCONJ
fnp-6285	82	80	clinical	clinical	ADJ
fnp-6285	82	81	immunology	immunology	NOUN
fnp-6285	82	82	,	,	PUNCT
fnp-6285	82	83	medical	medical	ADJ
fnp-6285	82	84	center	center	NOUN
fnp-6285	82	85	university	university	PROPN
fnp-6285	82	86	of	of	ADP
fnp-6285	82	87	freiburg	freiburg	PROPN
fnp-6285	82	88	,	,	PUNCT
fnp-6285	82	89	freiburg	freiburg	PROPN
fnp-6285	82	90	,	,	PUNCT
fnp-6285	82	91	germany	germany	PROPN
fnp-6285	82	92	institute	institute	PROPN
fnp-6285	82	93	of	of	ADP
fnp-6285	82	94	neuropathology	neuropathology	NOUN
fnp-6285	82	95	,	,	PUNCT
fnp-6285	82	96	university	university	NOUN
fnp-6285	82	97	hospital	hospital	NOUN
fnp-6285	82	98	zurich	zurich	PROPN
fnp-6285	82	99	,	,	PUNCT
fnp-6285	82	100	zurich	zurich	PROPN
fnp-6285	82	101	,	,	PUNCT
fnp-6285	82	102	switzerland	switzerland	PROPN
fnp-6285	82	103	here	here	ADV
fnp-6285	82	104	we	we	PRON
fnp-6285	82	105	report	report	VERB
fnp-6285	82	106	a	a	DET
fnp-6285	82	107	35	35	NUM
fnp-6285	82	108	-	-	PUNCT
fnp-6285	82	109	year	year	NOUN
fnp-6285	82	110	-	-	PUNCT
fnp-6285	82	111	old	old	ADJ
fnp-6285	82	112	man	man	NOUN
fnp-6285	82	113	with	with	ADP
fnp-6285	82	114	common	common	ADJ
fnp-6285	82	115	variable	variable	ADJ
fnp-6285	82	116	immunodeficiency	immunodeficiency	NOUN
fnp-6285	82	117	(	(	PUNCT
fnp-6285	82	118	cvid	cvid	NOUN
fnp-6285	82	119	)	)	PUNCT
fnp-6285	82	120	who	who	PRON
fnp-6285	82	121	presented	present	VERB
fnp-6285	82	122	after	after	ADP
fnp-6285	82	123	a	a	DET
fnp-6285	82	124	seizure	seizure	NOUN
fnp-6285	82	125	.	.	PUNCT
fnp-6285	83	1	he	he	PRON
fnp-6285	83	2	had	have	AUX
fnp-6285	83	3	undergone	undergo	VERB
fnp-6285	83	4	surgery	surgery	NOUN
fnp-6285	83	5	for	for	ADP
fnp-6285	83	6	a	a	DET
fnp-6285	83	7	congenital	congenital	ADJ
fnp-6285	83	8	heart	heart	NOUN
fnp-6285	83	9	defect	defect	NOUN
fnp-6285	83	10	at	at	ADP
fnp-6285	83	11	the	the	DET
fnp-6285	83	12	age	age	NOUN
fnp-6285	83	13	of	of	ADP
fnp-6285	83	14	seven	seven	NUM
fnp-6285	83	15	and	and	CCONJ
fnp-6285	83	16	had	have	AUX
fnp-6285	83	17	developed	develop	VERB
fnp-6285	83	18	splenomegaly	splenomegaly	ADJ
fnp-6285	83	19	,	,	PUNCT
fnp-6285	83	20	lymphadenopathy	lymphadenopathy	ADJ
fnp-6285	83	21	,	,	PUNCT
fnp-6285	83	22	interstitial	interstitial	ADJ
fnp-6285	83	23	lung	lung	NOUN
fnp-6285	83	24	disease	disease	NOUN
fnp-6285	83	25	and	and	CCONJ
fnp-6285	83	26	autoimmune	autoimmune	ADJ
fnp-6285	83	27	cytopenias	cytopenia	NOUN
fnp-6285	83	28	since	since	SCONJ
fnp-6285	83	29	the	the	DET
fnp-6285	83	30	age	age	NOUN
fnp-6285	83	31	of	of	ADP
fnp-6285	83	32	28	28	NUM
fnp-6285	83	33	.	.	PUNCT
fnp-6285	84	1	clinical	clinical	ADJ
fnp-6285	84	2	examination	examination	NOUN
fnp-6285	84	3	revealed	reveal	VERB
fnp-6285	84	4	subtle	subtle	ADJ
fnp-6285	84	5	facial	facial	ADJ
fnp-6285	84	6	dysmorphic	dysmorphic	ADJ
fnp-6285	84	7	features	feature	NOUN
fnp-6285	84	8	but	but	CCONJ
fnp-6285	84	9	no	no	DET
fnp-6285	84	10	focal	focal	ADJ
fnp-6285	84	11	neurological	neurological	ADJ
fnp-6285	84	12	deficits	deficit	NOUN
fnp-6285	84	13	.	.	PUNCT
fnp-6285	85	1	brain	brain	NOUN
fnp-6285	85	2	magnetic	magnetic	ADJ
fnp-6285	85	3	resonance	resonance	NOUN
fnp-6285	85	4	imaging	imaging	NOUN
fnp-6285	85	5	showed	show	VERB
fnp-6285	85	6	a	a	DET
fnp-6285	85	7	right	right	ADJ
fnp-6285	85	8	frontal	frontal	ADJ
fnp-6285	85	9	-	-	PUNCT
fnp-6285	85	10	insular	insular	ADJ
fnp-6285	85	11	lesion	lesion	NOUN
fnp-6285	85	12	with	with	ADP
fnp-6285	85	13	contrast	contrast	NOUN
fnp-6285	85	14	enhancement	enhancement	NOUN
fnp-6285	85	15	.	.	PUNCT
fnp-6285	86	1	a	a	DET
fnp-6285	86	2	biopsy	biopsy	NOUN
fnp-6285	86	3	confirmed	confirm	VERB
fnp-6285	86	4	histological	histological	ADJ
fnp-6285	86	5	evidence	evidence	NOUN
fnp-6285	86	6	of	of	ADP
fnp-6285	86	7	microgranulomatous	microgranulomatous	ADJ
fnp-6285	86	8	inflammation	inflammation	NOUN
fnp-6285	86	9	.	.	PUNCT
fnp-6285	87	1	polymorphic	polymorphic	ADJ
fnp-6285	87	2	ebv	ebv	NOUN
fnp-6285	87	3	-	-	PUNCT
fnp-6285	87	4	positive	positive	ADJ
fnp-6285	87	5	lymphoproliferation	lymphoproliferation	NOUN
fnp-6285	87	6	(	(	PUNCT
fnp-6285	87	7	formerly	formerly	ADV
fnp-6285	87	8	lymphomatoid	lymphomatoid	ADJ
fnp-6285	87	9	granulomatosis	granulomatosis	NOUN
fnp-6285	87	10	)	)	PUNCT
fnp-6285	87	11	and	and	CCONJ
fnp-6285	87	12	lymphoma	lymphoma	NOUN
fnp-6285	87	13	were	be	AUX
fnp-6285	87	14	excluded	exclude	VERB
fnp-6285	87	15	.	.	PUNCT
fnp-6285	88	1	a	a	DET
fnp-6285	88	2	multigene	multigene	ADJ
fnp-6285	88	3	panel	panel	NOUN
fnp-6285	88	4	identified	identify	VERB
fnp-6285	88	5	a	a	DET
fnp-6285	88	6	de	de	X
fnp-6285	88	7	novo	novo	NOUN
fnp-6285	88	8	pathogenic	pathogenic	ADJ
fnp-6285	88	9	variant	variant	NOUN
fnp-6285	88	10	c.7411del	c.7411del	ADP
fnp-6285	88	11	p.(arg2471aspfs*14	p.(arg2471aspfs*14	NOUN
fnp-6285	88	12	)	)	PUNCT
fnp-6285	88	13	in	in	ADP
fnp-6285	88	14	the	the	DET
fnp-6285	88	15	kmt2d	kmt2d	PROPN
fnp-6285	88	16	gene	gene	NOUN
fnp-6285	88	17	associated	associate	VERB
fnp-6285	88	18	with	with	ADP
fnp-6285	88	19	kabuki	kabuki	NOUN
fnp-6285	88	20	syndrome	syndrome	NOUN
fnp-6285	88	21	.	.	PUNCT
fnp-6285	89	1	cerebral	cerebral	ADJ
fnp-6285	89	2	inflammatory	inflammatory	ADJ
fnp-6285	89	3	lesions	lesion	NOUN
fnp-6285	89	4	are	be	AUX
fnp-6285	89	5	a	a	DET
fnp-6285	89	6	rare	rare	ADJ
fnp-6285	89	7	complication	complication	NOUN
fnp-6285	89	8	of	of	ADP
fnp-6285	89	9	kabuki	kabuki	NOUN
fnp-6285	89	10	syndrome	syndrome	NOUN
fnp-6285	89	11	and	and	CCONJ
fnp-6285	89	12	other	other	ADJ
fnp-6285	89	13	genetic	genetic	ADJ
fnp-6285	89	14	conditions	condition	NOUN
fnp-6285	89	15	associated	associate	VERB
fnp-6285	89	16	with	with	ADP
fnp-6285	89	17	cvid	cvid	PROPN
fnp-6285	89	18	,	,	PUNCT
fnp-6285	89	19	such	such	ADJ
fnp-6285	89	20	as	as	ADP
fnp-6285	89	21	ctla-4	ctla-4	NOUN
fnp-6285	89	22	deficiency	deficiency	NOUN
fnp-6285	89	23	.	.	PUNCT
fnp-6285	90	1	although	although	SCONJ
fnp-6285	90	2	neuroimaging	neuroimaging	NOUN
fnp-6285	90	3	may	may	AUX
fnp-6285	90	4	suggest	suggest	VERB
fnp-6285	90	5	demyelinating	demyelinate	VERB
fnp-6285	90	6	lesions	lesion	NOUN
fnp-6285	90	7	or	or	CCONJ
fnp-6285	90	8	neurosarcoidosis	neurosarcoidosis	ADJ
fnp-6285	90	9	,	,	PUNCT
fnp-6285	90	10	the	the	DET
fnp-6285	90	11	histologic	histologic	ADJ
fnp-6285	90	12	pattern	pattern	NOUN
fnp-6285	90	13	of	of	ADP
fnp-6285	90	14	t	t	NOUN
fnp-6285	90	15	-	-	PUNCT
fnp-6285	90	16	cell	cell	NOUN
fnp-6285	90	17	dominant	dominant	ADJ
fnp-6285	90	18	angiocentric	angiocentric	PROPN
fnp-6285	90	19	infiltrates	infiltrate	VERB
fnp-6285	90	20	shares	share	NOUN
fnp-6285	90	21	similarities	similarity	NOUN
fnp-6285	90	22	with	with	ADP
fnp-6285	90	23	cerebral	cerebral	ADJ
fnp-6285	90	24	lymphocytic	lymphocytic	ADJ
fnp-6285	90	25	vasculitis	vasculitis	NOUN
fnp-6285	90	26	.	.	PUNCT
fnp-6285	90	27	  	  	SPACE
fnp-6285	91	1	free	free	ADJ
fnp-6285	91	2	neuropathol	neuropathol	NOUN
fnp-6285	91	3	6:2:16	6:2:16	NUM
fnp-6285	91	4	dna	dna	PROPN
fnp-6285	91	5	methylation	methylation	NOUN
fnp-6285	91	6	profile	profile	NOUN
fnp-6285	91	7	in	in	ADP
fnp-6285	91	8	the	the	DET
fnp-6285	91	9	human	human	ADJ
fnp-6285	91	10	hypothalamus	hypothalamus	PROPN
fnp-6285	91	11	:	:	PUNCT
fnp-6285	91	12	comparison	comparison	NOUN
fnp-6285	91	13	of	of	ADP
fnp-6285	91	14	the	the	DET
fnp-6285	91	15	profiles	profile	NOUN
fnp-6285	91	16	of	of	ADP
fnp-6285	91	17	covid-19	covid-19	PROPN
fnp-6285	91	18	,	,	PUNCT
fnp-6285	91	19	alzheimer	alzheimer	PROPN
fnp-6285	91	20	’s	’s	PART
fnp-6285	91	21	and	and	CCONJ
fnp-6285	91	22	control	control	NOUN
fnp-6285	91	23	patients	patient	NOUN
fnp-6285	91	24	dewisme	dewisme	PROPN
fnp-6285	91	25	julie1,2	julie1,2	PROPN
fnp-6285	91	26	,	,	PUNCT
fnp-6285	91	27	sreekala	sreekala	PROPN
fnp-6285	91	28	nampoothiri1	nampoothiri1	PROPN
fnp-6285	91	29	,	,	PUNCT
fnp-6285	91	30	laurence	laurence	PROPN
fnp-6285	91	31	stechly3	stechly3	PROPN
fnp-6285	91	32	,	,	PUNCT
fnp-6285	91	33	florent	florent	PROPN
fnp-6285	91	34	sauvé1	sauvé1	PROPN
fnp-6285	91	35	,	,	PUNCT
fnp-6285	91	36	fabienne	fabienne	PROPN
fnp-6285	91	37	escande3	escande3	PROPN
fnp-6285	91	38	,	,	PUNCT
fnp-6285	91	39	claude	claude	PROPN
fnp-6285	91	40	-	-	PUNCT
fnp-6285	91	41	alain	alain	PROPN
fnp-6285	91	42	maurage1,2	maurage1,2	PROPN
fnp-6285	91	43	,	,	PUNCT
fnp-6285	91	44	vincent	vincent	PROPN
fnp-6285	91	45	prevot1	prevot1	PROPN
fnp-6285	91	46	univ	univ	PROPN
fnp-6285	91	47	.	.	PUNCT
fnp-6285	92	1	lille	lille	PROPN
fnp-6285	92	2	,	,	PUNCT
fnp-6285	92	3	inserm	inserm	PROPN
fnp-6285	92	4	,	,	PUNCT
fnp-6285	92	5	chu	chu	PROPN
fnp-6285	92	6	lille	lille	PROPN
fnp-6285	92	7	,	,	PUNCT
fnp-6285	92	8	lille	lille	PROPN
fnp-6285	92	9	neuroscience	neuroscience	NOUN
fnp-6285	92	10	&	&	CCONJ
fnp-6285	92	11	cognition	cognition	NOUN
fnp-6285	92	12	,	,	PUNCT
fnp-6285	92	13	umr	umr	PROPN
fnp-6285	92	14	-	-	PUNCT
fnp-6285	92	15	s	s	PART
fnp-6285	92	16	1172	1172	NUM
fnp-6285	92	17	,	,	PUNCT
fnp-6285	92	18	lille	lille	PROPN
fnp-6285	92	19	,	,	PUNCT
fnp-6285	92	20	france	france	PROPN
fnp-6285	92	21	pathology	pathology	PROPN
fnp-6285	92	22	department	department	PROPN
fnp-6285	92	23	,	,	PUNCT
fnp-6285	92	24	lille	lille	PROPN
fnp-6285	92	25	university	university	PROPN
fnp-6285	92	26	,	,	PUNCT
fnp-6285	92	27	medical	medical	ADJ
fnp-6285	92	28	centre	centre	NOUN
fnp-6285	92	29	,	,	PUNCT
fnp-6285	92	30	lille	lille	PROPN
fnp-6285	92	31	,	,	PUNCT
fnp-6285	92	32	france	france	PROPN
fnp-6285	92	33	molecular	molecular	ADJ
fnp-6285	92	34	biology	biology	NOUN
fnp-6285	92	35	department	department	NOUN
fnp-6285	92	36	,	,	PUNCT
fnp-6285	92	37	lille	lille	PROPN
fnp-6285	92	38	university	university	PROPN
fnp-6285	92	39	,	,	PUNCT
fnp-6285	92	40	medical	medical	ADJ
fnp-6285	92	41	centre	centre	NOUN
fnp-6285	92	42	,	,	PUNCT
fnp-6285	92	43	lille	lille	PROPN
fnp-6285	92	44	,	,	PUNCT
fnp-6285	92	45	france	france	PROPN
fnp-6285	92	46	introduction	introduction	NOUN
fnp-6285	92	47	:	:	PUNCT
fnp-6285	92	48	sars	sar	NOUN
fnp-6285	92	49	-	-	PUNCT
fnp-6285	92	50	cov-2	cov-2	NUM
fnp-6285	92	51	could	could	AUX
fnp-6285	92	52	be	be	AUX
fnp-6285	92	53	associated	associate	VERB
fnp-6285	92	54	with	with	ADP
fnp-6285	92	55	neurological	neurological	ADJ
fnp-6285	92	56	and	and	CCONJ
fnp-6285	92	57	endocrine	endocrine	ADJ
fnp-6285	92	58	symptoms	symptom	NOUN
fnp-6285	92	59	,	,	PUNCT
fnp-6285	92	60	linked	link	VERB
fnp-6285	92	61	to	to	ADP
fnp-6285	92	62	the	the	DET
fnp-6285	92	63	infection	infection	NOUN
fnp-6285	92	64	of	of	ADP
fnp-6285	92	65	the	the	DET
fnp-6285	92	66	central	central	ADJ
fnp-6285	92	67	nervous	nervous	ADJ
fnp-6285	92	68	system	system	NOUN
fnp-6285	92	69	,	,	PUNCT
fnp-6285	92	70	particularly	particularly	ADV
fnp-6285	92	71	via	via	ADP
fnp-6285	92	72	circumventricular	circumventricular	ADJ
fnp-6285	92	73	organs	organ	NOUN
fnp-6285	92	74	,	,	PUNCT
fnp-6285	92	75	including	include	VERB
fnp-6285	92	76	the	the	DET
fnp-6285	92	77	median	median	ADJ
fnp-6285	92	78	eminence	eminence	NOUN
fnp-6285	92	79	of	of	ADP
fnp-6285	92	80	the	the	DET
fnp-6285	92	81	hypothalamus	hypothalamus	NOUN
fnp-6285	92	82	.	.	PUNCT
fnp-6285	93	1	it	it	PRON
fnp-6285	93	2	may	may	AUX
fnp-6285	93	3	also	also	ADV
fnp-6285	93	4	interfere	interfere	VERB
fnp-6285	93	5	with	with	ADP
fnp-6285	93	6	the	the	DET
fnp-6285	93	7	progression	progression	NOUN
fnp-6285	93	8	of	of	ADP
fnp-6285	93	9	alzheimer	alzheimer	PROPN
fnp-6285	93	10	's	's	PART
fnp-6285	93	11	disease	disease	NOUN
fnp-6285	93	12	.	.	PUNCT
fnp-6285	94	1	our	our	PRON
fnp-6285	94	2	objective	objective	NOUN
fnp-6285	94	3	was	be	AUX
fnp-6285	94	4	to	to	PART
fnp-6285	94	5	compare	compare	VERB
fnp-6285	94	6	the	the	DET
fnp-6285	94	7	dna	dna	PROPN
fnp-6285	94	8	methylation	methylation	NOUN
fnp-6285	94	9	profile	profile	NOUN
fnp-6285	94	10	of	of	ADP
fnp-6285	94	11	post	post	ADJ
fnp-6285	94	12	-	-	ADJ
fnp-6285	94	13	mortem	mortem	ADJ
fnp-6285	94	14	hypothalamic	hypothalamic	ADJ
fnp-6285	94	15	tissue	tissue	NOUN
fnp-6285	94	16	from	from	ADP
fnp-6285	94	17	covid-19	covid-19	PROPN
fnp-6285	94	18	patients	patient	NOUN
fnp-6285	94	19	with	with	ADP
fnp-6285	94	20	that	that	PRON
fnp-6285	94	21	of	of	ADP
fnp-6285	94	22	controls	control	NOUN
fnp-6285	94	23	and	and	CCONJ
fnp-6285	94	24	of	of	ADP
fnp-6285	94	25	patients	patient	NOUN
fnp-6285	94	26	who	who	PRON
fnp-6285	94	27	died	die	VERB
fnp-6285	94	28	in	in	ADP
fnp-6285	94	29	the	the	DET
fnp-6285	94	30	context	context	NOUN
fnp-6285	94	31	of	of	ADP
fnp-6285	94	32	alzheimer	alzheimer	PROPN
fnp-6285	94	33	’s	’s	PART
fnp-6285	94	34	disease	disease	NOUN
fnp-6285	94	35	.	.	PUNCT
fnp-6285	95	1	methods	method	NOUN
fnp-6285	95	2	:	:	PUNCT
fnp-6285	95	3	we	we	PRON
fnp-6285	95	4	studied	study	VERB
fnp-6285	95	5	the	the	DET
fnp-6285	95	6	dna	dna	PROPN
fnp-6285	95	7	methylation	methylation	NOUN
fnp-6285	95	8	profile	profile	NOUN
fnp-6285	95	9	of	of	ADP
fnp-6285	95	10	formalin	formalin	NOUN
fnp-6285	95	11	-	-	PUNCT
fnp-6285	95	12	fixed	fix	VERB
fnp-6285	95	13	and	and	CCONJ
fnp-6285	95	14	frozen	frozen	ADJ
fnp-6285	95	15	hypothalamic	hypothalamic	ADJ
fnp-6285	95	16	tissue	tissue	NOUN
fnp-6285	95	17	from	from	ADP
fnp-6285	95	18	4	4	NUM
fnp-6285	95	19	covid-19	covid-19	PROPN
fnp-6285	95	20	patients	patient	NOUN
fnp-6285	95	21	,	,	PUNCT
fnp-6285	95	22	6	6	NUM
fnp-6285	95	23	controls	control	NOUN
fnp-6285	95	24	,	,	PUNCT
fnp-6285	95	25	and	and	CCONJ
fnp-6285	95	26	6	6	NUM
fnp-6285	95	27	alzheimer	alzheimer	NOUN
fnp-6285	95	28	's	's	PART
fnp-6285	95	29	patients	patient	NOUN
fnp-6285	95	30	using	use	VERB
fnp-6285	95	31	illumina	illumina	PROPN
fnp-6285	95	32	®	®	PROPN
fnp-6285	95	33	infinium	infinium	PROPN
fnp-6285	95	34	methylationepi	methylationepi	PROPN
fnp-6285	95	35	ctechnology	ctechnology	PROPN
fnp-6285	95	36	.	.	PUNCT
fnp-6285	96	1	results	result	NOUN
fnp-6285	96	2	:	:	PUNCT
fnp-6285	96	3	the	the	DET
fnp-6285	96	4	comparison	comparison	NOUN
fnp-6285	96	5	of	of	ADP
fnp-6285	96	6	the	the	DET
fnp-6285	96	7	cpg	cpg	NOUN
fnp-6285	96	8	methylation	methylation	NOUN
fnp-6285	96	9	profile	profile	NOUN
fnp-6285	96	10	of	of	ADP
fnp-6285	96	11	covid-19	covid-19	PROPN
fnp-6285	96	12	patients	patient	NOUN
fnp-6285	96	13	to	to	ADP
fnp-6285	96	14	controls	control	NOUN
fnp-6285	96	15	revealed	reveal	VERB
fnp-6285	96	16	only	only	ADV
fnp-6285	96	17	4	4	NUM
fnp-6285	96	18	differentially	differentially	ADV
fnp-6285	96	19	methylated	methylate	VERB
fnp-6285	96	20	sites	site	NOUN
fnp-6285	96	21	.	.	PUNCT
fnp-6285	97	1	in	in	ADP
fnp-6285	97	2	contrast	contrast	NOUN
fnp-6285	97	3	,	,	PUNCT
fnp-6285	97	4	we	we	PRON
fnp-6285	97	5	observed	observe	VERB
fnp-6285	97	6	numerous	numerous	ADJ
fnp-6285	97	7	dna	dna	PROPN
fnp-6285	97	8	methylation	methylation	NOUN
fnp-6285	97	9	differences	difference	NOUN
fnp-6285	97	10	between	between	ADP
fnp-6285	97	11	alzheimer	alzheimer	PROPN
fnp-6285	97	12	's	's	PART
fnp-6285	97	13	patients	patient	NOUN
fnp-6285	97	14	and	and	CCONJ
fnp-6285	97	15	both	both	DET
fnp-6285	97	16	covid-19	covid-19	PROPN
fnp-6285	97	17	patients	patient	NOUN
fnp-6285	97	18	and	and	CCONJ
fnp-6285	97	19	controls	control	NOUN
fnp-6285	97	20	.	.	PUNCT
fnp-6285	98	1	conclusion	conclusion	NOUN
fnp-6285	98	2	:	:	PUNCT
fnp-6285	98	3	our	our	PRON
fnp-6285	98	4	results	result	NOUN
fnp-6285	98	5	suggest	suggest	VERB
fnp-6285	98	6	that	that	SCONJ
fnp-6285	98	7	hypothalamic	hypothalamic	ADJ
fnp-6285	98	8	epigenetic	epigenetic	ADJ
fnp-6285	98	9	modifications	modification	NOUN
fnp-6285	98	10	are	be	AUX
fnp-6285	98	11	more	more	ADV
fnp-6285	98	12	pronounced	pronounce	VERB
fnp-6285	98	13	in	in	ADP
fnp-6285	98	14	alzheimer	alzheimer	PROPN
fnp-6285	98	15	's	's	PART
fnp-6285	98	16	patients	patient	NOUN
fnp-6285	98	17	than	than	ADP
fnp-6285	98	18	in	in	ADP
fnp-6285	98	19	covid-19	covid-19	PROPN
fnp-6285	98	20	patients	patient	NOUN
fnp-6285	98	21	compared	compare	VERB
fnp-6285	98	22	to	to	ADP
fnp-6285	98	23	controls	control	NOUN
fnp-6285	98	24	,	,	PUNCT
fnp-6285	98	25	highlighting	highlight	VERB
fnp-6285	98	26	numerous	numerous	ADJ
fnp-6285	98	27	candidate	candidate	NOUN
fnp-6285	98	28	cpg	cpg	NOUN
fnp-6285	98	29	sites	site	NOUN
fnp-6285	98	30	in	in	ADP
fnp-6285	98	31	alzheimer	alzheimer	PROPN
fnp-6285	98	32	's	's	PART
fnp-6285	98	33	patients	patient	NOUN
fnp-6285	98	34	.	.	PUNCT
fnp-6285	99	1	the	the	DET
fnp-6285	99	2	study	study	NOUN
fnp-6285	99	3	will	will	AUX
fnp-6285	99	4	continue	continue	VERB
fnp-6285	99	5	with	with	ADP
fnp-6285	99	6	1	1	NUM
fnp-6285	99	7	)	)	PUNCT
fnp-6285	99	8	the	the	DET
fnp-6285	99	9	inclusion	inclusion	NOUN
fnp-6285	99	10	of	of	ADP
fnp-6285	99	11	new	new	ADJ
fnp-6285	99	12	patients	patient	NOUN
fnp-6285	99	13	,	,	PUNCT
fnp-6285	99	14	2	2	X
fnp-6285	99	15	)	)	PUNCT
fnp-6285	99	16	a	a	DET
fnp-6285	99	17	more	more	ADV
fnp-6285	99	18	specific	specific	ADJ
fnp-6285	99	19	study	study	NOUN
fnp-6285	99	20	of	of	ADP
fnp-6285	99	21	cpg	cpg	PROPN
fnp-6285	99	22	islands	island	NOUN
fnp-6285	99	23	in	in	ADP
fnp-6285	99	24	gene	gene	NOUN
fnp-6285	99	25	promoter	promoter	NOUN
fnp-6285	99	26	regions	region	NOUN
fnp-6285	99	27	.	.	PUNCT
fnp-6285	99	28	  	  	SPACE
fnp-6285	100	1	free	free	ADJ
fnp-6285	100	2	neuropathol	neuropathol	NOUN
fnp-6285	100	3	6:2:17	6:2:17	NUM
fnp-6285	100	4	neuropathology	neuropathology	NOUN
fnp-6285	100	5	of	of	ADP
fnp-6285	100	6	the	the	DET
fnp-6285	100	7	first	first	ADJ
fnp-6285	100	8	experimental	experimental	ADJ
fnp-6285	100	9	transmission	transmission	NOUN
fnp-6285	100	10	of	of	ADP
fnp-6285	100	11	the	the	DET
fnp-6285	100	12	atypical	atypical	ADJ
fnp-6285	100	13	prionopathy	prionopathy	ADJ
fnp-6285	100	14	vpspr	vpspr	NOUN
fnp-6285	100	15	(	(	PUNCT
fnp-6285	100	16	variably	variably	ADV
fnp-6285	100	17	protease	protease	NOUN
fnp-6285	100	18	sensitive	sensitive	NOUN
fnp-6285	100	19	)	)	PUNCT
fnp-6285	100	20	to	to	ADP
fnp-6285	100	21	non	non	ADJ
fnp-6285	100	22	-	-	ADJ
fnp-6285	100	23	human	human	ADJ
fnp-6285	100	24	primate	primate	NOUN
fnp-6285	100	25	j.	j.	PROPN
fnp-6285	100	26	mikol1	mikol1	PROPN
fnp-6285	100	27	,	,	PUNCT
fnp-6285	100	28	j.	j.	PROPN
fnp-6285	100	29	delmotte1	delmotte1	PROPN
fnp-6285	100	30	,	,	PUNCT
fnp-6285	100	31	w.	w.	PROPN
fnp-6285	100	32	zou2	zou2	PROPN
fnp-6285	100	33	,	,	PUNCT
fnp-6285	100	34	j.p	j.p	PROPN
fnp-6285	100	35	.	.	PROPN
fnp-6285	100	36	deslys1	deslys1	PROPN
fnp-6285	100	37	,	,	PUNCT
fnp-6285	100	38	e.	e.	PROPN
fnp-6285	100	39	comoy1	comoy1	PROPN
fnp-6285	100	40	cea	cea	PROPN
fnp-6285	100	41	/	/	SYM
fnp-6285	100	42	drf	drf	PROPN
fnp-6285	100	43	/	/	SYM
fnp-6285	100	44	jacol	jacol	PROPN
fnp-6285	100	45	/	/	SYM
fnp-6285	100	46	sepia	sepia	NOUN
fnp-6285	100	47	,	,	PUNCT
fnp-6285	100	48	18	18	NUM
fnp-6285	100	49	route	route	NOUN
fnp-6285	100	50	du	du	PROPN
fnp-6285	100	51	panorama	panorama	NOUN
fnp-6285	100	52	,	,	PUNCT
fnp-6285	100	53	bp6	bp6	NOUN
fnp-6285	100	54	92265	92265	NUM
fnp-6285	100	55	,	,	PUNCT
fnp-6285	100	56	fontenay	fontenay	PROPN
fnp-6285	100	57	aux	aux	PROPN
fnp-6285	100	58	roses	roses	PROPN
fnp-6285	100	59	,	,	PUNCT
fnp-6285	100	60	france	france	PROPN
fnp-6285	100	61	the	the	DET
fnp-6285	100	62	first	first	ADJ
fnp-6285	100	63	affiliated	affiliate	VERB
fnp-6285	100	64	hospital	hospital	NOUN
fnp-6285	100	65	of	of	ADP
fnp-6285	100	66	nanchang	nanchang	PROPN
fnp-6285	100	67	university	university	PROPN
fnp-6285	100	68	,	,	PUNCT
fnp-6285	100	69	17	17	NUM
fnp-6285	100	70	yongwaizheng	yongwaizheng	PROPN
fnp-6285	100	71	street	street	PROPN
fnp-6285	100	72	330006	330006	NUM
fnp-6285	100	73	,	,	PUNCT
fnp-6285	100	74	nanchang	nanchang	PROPN
fnp-6285	100	75	,	,	PUNCT
fnp-6285	100	76	jiangxi	jiangxi	PROPN
fnp-6285	100	77	,	,	PUNCT
fnp-6285	100	78	china	china	PROPN
fnp-6285	100	79	presumed	presume	VERB
fnp-6285	100	80	to	to	PART
fnp-6285	100	81	be	be	AUX
fnp-6285	100	82	the	the	DET
fnp-6285	100	83	sporadic	sporadic	ADJ
fnp-6285	100	84	form	form	NOUN
fnp-6285	100	85	of	of	ADP
fnp-6285	100	86	genetic	genetic	ADJ
fnp-6285	100	87	cjd	cjd	NOUN
fnp-6285	100	88	v180i	v180i	PROPN
fnp-6285	100	89	,	,	PUNCT
fnp-6285	100	90	vpspr	vpspr	NOUN
fnp-6285	100	91	is	be	AUX
fnp-6285	100	92	classically	classically	ADV
fnp-6285	100	93	considered	consider	VERB
fnp-6285	100	94	as	as	ADP
fnp-6285	100	95	an	an	DET
fnp-6285	100	96	atypical	atypical	ADJ
fnp-6285	100	97	dementia	dementia	NOUN
fnp-6285	100	98	,	,	PUNCT
fnp-6285	100	99	incompletely	incompletely	ADV
fnp-6285	100	100	,	,	PUNCT
fnp-6285	100	101	if	if	SCONJ
fnp-6285	100	102	any	any	PRON
fnp-6285	100	103	-	-	PUNCT
fnp-6285	100	104	transmissible	transmissible	NOUN
fnp-6285	100	105	in	in	ADP
fnp-6285	100	106	experimental	experimental	ADJ
fnp-6285	100	107	rodent	rodent	NOUN
fnp-6285	100	108	models	model	NOUN
fnp-6285	100	109	and	and	CCONJ
fnp-6285	100	110	often	often	ADV
fnp-6285	100	111	firstly	firstly	ADV
fnp-6285	100	112	misdiagnosed	misdiagnose	VERB
fnp-6285	100	113	.	.	PUNCT
fnp-6285	101	1	we	we	PRON
fnp-6285	101	2	report	report	VERB
fnp-6285	101	3	here	here	ADV
fnp-6285	101	4	the	the	DET
fnp-6285	101	5	first	first	ADJ
fnp-6285	101	6	transmission	transmission	NOUN
fnp-6285	101	7	of	of	ADP
fnp-6285	101	8	vpspr	vpspr	NOUN
fnp-6285	101	9	in	in	ADP
fnp-6285	101	10	a	a	DET
fnp-6285	101	11	cynomolgus	cynomolgus	ADJ
fnp-6285	101	12	macaque	macaque	NOUN
fnp-6285	101	13	,	,	PUNCT
fnp-6285	101	14	8.5	8.5	NUM
fnp-6285	101	15	years	year	NOUN
fnp-6285	101	16	after	after	ADP
fnp-6285	101	17	intracerebral	intracerebral	ADJ
fnp-6285	101	18	inoculation	inoculation	NOUN
fnp-6285	101	19	of	of	ADP
fnp-6285	101	20	a	a	DET
fnp-6285	101	21	brain	brain	NOUN
fnp-6285	101	22	homogenate	homogenate	NOUN
fnp-6285	101	23	from	from	ADP
fnp-6285	101	24	a	a	DET
fnp-6285	101	25	75	75	NUM
fnp-6285	101	26	-	-	PUNCT
fnp-6285	101	27	years	year	NOUN
fnp-6285	101	28	-	-	PUNCT
fnp-6285	101	29	old	old	ADJ
fnp-6285	101	30	mv	mv	PROPN
fnp-6285	101	31	patient	patient	NOUN
fnp-6285	101	32	.	.	PUNCT
fnp-6285	102	1	neuropathology	neuropathology	NOUN
fnp-6285	102	2	showed	show	VERB
fnp-6285	102	3	all	all	DET
fnp-6285	102	4	the	the	DET
fnp-6285	102	5	elements	element	NOUN
fnp-6285	102	6	of	of	ADP
fnp-6285	102	7	the	the	DET
fnp-6285	102	8	triad	triad	NOUN
fnp-6285	102	9	,	,	PUNCT
fnp-6285	102	10	with	with	ADP
fnp-6285	102	11	a	a	DET
fnp-6285	102	12	specific	specific	ADJ
fnp-6285	102	13	profile	profile	NOUN
fnp-6285	102	14	.	.	PUNCT
fnp-6285	103	1	notably	notably	ADV
fnp-6285	103	2	,	,	PUNCT
fnp-6285	103	3	immunostaining	immunostaining	NOUN
fnp-6285	103	4	showed	show	VERB
fnp-6285	103	5	very	very	ADV
fnp-6285	103	6	thin	thin	ADJ
fnp-6285	103	7	synaptic	synaptic	ADJ
fnp-6285	103	8	and	and	CCONJ
fnp-6285	103	9	neocortical	neocortical	ADJ
fnp-6285	103	10	fuzzy	fuzzy	ADJ
fnp-6285	103	11	deposits	deposit	NOUN
fnp-6285	103	12	of	of	ADP
fnp-6285	103	13	prpd	prpd	NOUN
fnp-6285	103	14	and	and	CCONJ
fnp-6285	103	15	biochemistry	biochemistry	NOUN
fnp-6285	103	16	revealed	reveal	VERB
fnp-6285	103	17	lower	low	ADJ
fnp-6285	103	18	amounts	amount	NOUN
fnp-6285	103	19	of	of	ADP
fnp-6285	103	20	prpres	prpre	NOUN
fnp-6285	103	21	than	than	ADP
fnp-6285	103	22	in	in	ADP
fnp-6285	103	23	other	other	ADJ
fnp-6285	103	24	prion	prion	NOUN
fnp-6285	103	25	strains	strain	NOUN
fnp-6285	103	26	,	,	PUNCT
fnp-6285	103	27	with	with	ADP
fnp-6285	103	28	a	a	DET
fnp-6285	103	29	specific	specific	ADJ
fnp-6285	103	30	ladder	ladder	NOUN
fnp-6285	103	31	-	-	PUNCT
fnp-6285	103	32	like	like	ADJ
fnp-6285	103	33	glycophoretic	glycophoretic	ADJ
fnp-6285	103	34	profile	profile	NOUN
fnp-6285	103	35	.	.	PUNCT
fnp-6285	104	1	in	in	ADP
fnp-6285	104	2	addition	addition	NOUN
fnp-6285	104	3	,	,	PUNCT
fnp-6285	104	4	we	we	PRON
fnp-6285	104	5	observed	observe	VERB
fnp-6285	104	6	unusual	unusual	ADJ
fnp-6285	104	7	massive	massive	ADJ
fnp-6285	104	8	neocortical	neocortical	ADJ
fnp-6285	104	9	aβ	aβ	NOUN
fnp-6285	104	10	deposits	deposit	NOUN
fnp-6285	104	11	that	that	PRON
fnp-6285	104	12	are	be	AUX
fnp-6285	104	13	absent	absent	ADJ
fnp-6285	104	14	in	in	ADP
fnp-6285	104	15	mid	mid	ADJ
fnp-6285	104	16	-	-	ADJ
fnp-6285	104	17	aged	aged	ADJ
fnp-6285	104	18	controls	control	NOUN
fnp-6285	104	19	(	(	PUNCT
fnp-6285	104	20	13.5	13.5	NUM
fnp-6285	104	21	years	year	NOUN
fnp-6285	104	22	)	)	PUNCT
fnp-6285	104	23	,	,	PUNCT
fnp-6285	104	24	and	and	CCONJ
fnp-6285	104	25	different	different	ADJ
fnp-6285	104	26	from	from	ADP
fnp-6285	104	27	those	those	PRON
fnp-6285	104	28	observed	observe	VERB
fnp-6285	104	29	in	in	ADP
fnp-6285	104	30	two	two	NUM
fnp-6285	104	31	-	-	PUNCT
fnp-6285	104	32	fold	fold	VERB
fnp-6285	104	33	older	old	ADJ
fnp-6285	104	34	animals	animal	NOUN
fnp-6285	104	35	.	.	PUNCT
fnp-6285	105	1	secondary	secondary	ADJ
fnp-6285	105	2	transmission	transmission	NOUN
fnp-6285	105	3	was	be	AUX
fnp-6285	105	4	observed	observe	VERB
fnp-6285	105	5	in	in	ADP
fnp-6285	105	6	a	a	DET
fnp-6285	105	7	limited	limited	ADJ
fnp-6285	105	8	number	number	NOUN
fnp-6285	105	9	of	of	ADP
fnp-6285	105	10	transgenic	transgenic	NOUN
fnp-6285	105	11	mice	mouse	NOUN
fnp-6285	105	12	.	.	PUNCT
fnp-6285	106	1	the	the	DET
fnp-6285	106	2	transmission	transmission	NOUN
fnp-6285	106	3	between	between	ADP
fnp-6285	106	4	vpspr	vpspr	NOUN
fnp-6285	106	5	and	and	CCONJ
fnp-6285	106	6	amyloidosis	amyloidosis	NOUN
fnp-6285	106	7	will	will	AUX
fnp-6285	106	8	be	be	AUX
fnp-6285	106	9	discussed	discuss	VERB
fnp-6285	106	10	.	.	PUNCT
fnp-6285	107	1	copyright	copyright	NOUN
fnp-6285	107	2	:	:	PUNCT
fnp-6285	107	3	©	©	PROPN
fnp-6285	107	4	2025	2025	NUM
fnp-6285	107	5	the	the	DET
fnp-6285	107	6	author(s	author(s	NOUN
fnp-6285	107	7	)	)	PUNCT
fnp-6285	107	8	.	.	PUNCT
fnp-6285	108	1	this	this	PRON
fnp-6285	108	2	is	be	AUX
fnp-6285	108	3	an	an	DET
fnp-6285	108	4	open	open	ADJ
fnp-6285	108	5	access	access	NOUN
fnp-6285	108	6	article	article	NOUN
fnp-6285	108	7	distributed	distribute	VERB
fnp-6285	108	8	under	under	ADP
fnp-6285	108	9	the	the	DET
fnp-6285	108	10	terms	term	NOUN
fnp-6285	108	11	of	of	ADP
fnp-6285	108	12	the	the	DET
fnp-6285	108	13	creative	creative	ADJ
fnp-6285	108	14	commons	common	NOUN
fnp-6285	108	15	attribution	attribution	NOUN
fnp-6285	108	16	4.0	4.0	NUM
fnp-6285	108	17	international	international	ADJ
fnp-6285	108	18	license	license	NOUN
fnp-6285	108	19	(	(	PUNCT
fnp-6285	108	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-6285	108	21	)	)	PUNCT
fnp-6285	108	22	,	,	PUNCT
fnp-6285	108	23	which	which	PRON
fnp-6285	108	24	permits	permit	VERB
fnp-6285	108	25	unrestricted	unrestricted	ADJ
fnp-6285	108	26	use	use	NOUN
fnp-6285	108	27	,	,	PUNCT
fnp-6285	108	28	distribution	distribution	NOUN
fnp-6285	108	29	,	,	PUNCT
fnp-6285	108	30	and	and	CCONJ
fnp-6285	108	31	reproduction	reproduction	NOUN
fnp-6285	108	32	in	in	ADP
fnp-6285	108	33	any	any	DET
fnp-6285	108	34	medium	medium	NOUN
fnp-6285	108	35	,	,	PUNCT
fnp-6285	108	36	provided	provide	VERB
fnp-6285	108	37	the	the	DET
fnp-6285	108	38	original	original	ADJ
fnp-6285	108	39	author	author	NOUN
fnp-6285	108	40	and	and	CCONJ
fnp-6285	108	41	source	source	NOUN
fnp-6285	108	42	are	be	AUX
fnp-6285	108	43	credited	credit	VERB
fnp-6285	108	44	,	,	PUNCT
fnp-6285	108	45	a	a	DET
fnp-6285	108	46	link	link	NOUN
fnp-6285	108	47	to	to	ADP
fnp-6285	108	48	the	the	DET
fnp-6285	108	49	creative	creative	ADJ
fnp-6285	108	50	commons	common	NOUN
fnp-6285	108	51	license	license	NOUN
fnp-6285	108	52	is	be	AUX
fnp-6285	108	53	provided	provide	VERB
fnp-6285	108	54	,	,	PUNCT
fnp-6285	108	55	and	and	CCONJ
fnp-6285	108	56	any	any	DET
fnp-6285	108	57	changes	change	NOUN
fnp-6285	108	58	are	be	AUX
fnp-6285	108	59	indicated	indicate	VERB
fnp-6285	108	60	.	.	PUNCT
fnp-6285	109	1	the	the	DET
fnp-6285	109	2	creative	creative	ADJ
fnp-6285	109	3	commons	common	NOUN
fnp-6285	109	4	public	public	ADJ
fnp-6285	109	5	domain	domain	NOUN
fnp-6285	109	6	dedication	dedication	NOUN
fnp-6285	109	7	waiver	waiver	NOUN
fnp-6285	109	8	(	(	PUNCT
fnp-6285	109	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-6285	109	10	)	)	PUNCT
fnp-6285	109	11	applies	apply	VERB
fnp-6285	109	12	to	to	ADP
fnp-6285	109	13	the	the	DET
fnp-6285	109	14	data	datum	NOUN
fnp-6285	109	15	made	make	VERB
fnp-6285	109	16	available	available	ADJ
fnp-6285	109	17	in	in	ADP
fnp-6285	109	18	this	this	DET
fnp-6285	109	19	article	article	NOUN
fnp-6285	109	20	,	,	PUNCT
fnp-6285	109	21	unless	unless	SCONJ
fnp-6285	109	22	otherwise	otherwise	ADV
fnp-6285	109	23	stated	state	VERB
fnp-6285	109	24	.	.	PUNCT