ffhd: A Pathfinder

This is a computer-generated pathfinder created against the Distant Reader study called ffhd.

Each Distant Reader study carrel is composed of many individual items. Each item is bibliographically described with author, title, date, summary, and keyword values. Below is a list of the items' most signficant keywords as well as lists of the items themselves. Purpusing the content of this pathfinder provides the student, researcher, or scholar with one way to get their heads around the scope of the carrel. The keywords include:

Food; Health; Cancer; Foods; Extract; Protein; Group; Fatigue; Disease; Cells; Sciences; Activity; Glucose; Acid; Blood; Milk; Vitamin; Department; Gut; Placebo; Antioxidant; Oil; Medicine; Extracts; Diet; Sleep; Liver; Weight; Center; Microbiota; Japan; Probiotics; Powder; Curcumin; Insulin; Soy; Diabetes; Cell; Muscle; Auckland; Aminoacylase; Acacia; Metabolic; Products; Yogurt; Whey; Regensburg; Obesity; Sucrose; Fruits; Dag; Phayao; Fpp; Egcg; Body; Bacillus; Fatty; Vegetables; Peel; Processing; Rockford; Iron; Rats; Ginger; Obese; Mice; Flavonoids; Co.; Cholesterol; Levels; Rice; Soil; Cherry; Plant; Sprouts; Coffee; N1487; Ala; Tokyo; Compounds; Plants; Diseases; Spirulina; Juice; Stress; Women; Mekabu; Science; Citrus; Berries; Groups; Peptide; Mothers; Growth; Serum; Technology; Collagen; Universidad; Bioactives; Compound; Hypercholesterolemia; Ibs; Ashwagandha; Colitis; Pdx; Level; Arginine; Wheatgrass; Astana; Dark; Discomfort; Fiber; Senticosus; Pectin; Flour; Hong; Safety; Metabolism; Boiled; Vispo; Fruit; Flexibility; Ldl; Fish; Ferritin; Environment; Fsl; Hydroponic; Feeding; Drying; Coriander; Anggur; Expression; Butyricum; Ginseng; Lifestyle; Bso; Hela; Grapevine; Cerevisiae; Analysis; Outcomes; Bph; Degranulation; Adiponectin; Capillaries; Antibodies; Vitalutein; Aging; Nutraceuticals; Dhc; Hla; Review; Cl22209; Dogwood; Longifolia; Armeniacae; Pigmentation; Officinale; Brucellosis; Amcn; Components; Illnesses; Encapsulation; Bergen; Carolina; Development; Cho; Biophenols; Ahcc; Brain; Wroclaw; Ascalonicum; Flavocoxid; Resveratrol; Bari; Beam; Adherence; Ceramide; Hat; Manila; Calafate; Index; Miami; Cookies; Linseed; Ciliatum; Density; Austria; Fibromyalgia; Iran; Glutathione; Batatas

Depending on how this pathfinder was created, many of the bibliographic sections will include elaborations on the meaning(s) of the given keywords. These elaborations were generated by feeding the items' summaries to a large langauge model and asking the model to address the question, "What is X?", where "X" is the keyword. The result will be a few sentences of elaboration. Be forewarned. The elaborations are often plausible, but they should not be take as truth. Instead, they should be taken as points for consideration.

• Use of probiotics for nutritional enrichment of dairy products by Hati, Subrota; Prajapati, JB (2022) - This review intends to compile and analyze the literature pertaining to the use of probiotics as food products, especially for nutritional enrichment. Keywords: Probiotics, prebiotics, nutritional enrichment, fermented foods, bioavailability, efficacy, regulatory, safety, synbiotic, functional food Downloads Keywords: food; issn
• Lipid Replacement Therapy Functional Food Formulation with NT Factor for Reducing Weight, Girth, Body Mass, Appetite and Fatigue While Improving Blood Lipid Profiles by Ellithorpe, Rita R.; Settineri, Robert; Jacques, Brett; Mitchell, Cyndee A.; Nicolson, Garth L. (2012) - No. 1 (2012): January 2012 / Research Articles Lipid Replacement Therapy Functional Food Formulation with NT Factor for Reducing Weight, Girth, Body Mass, Appetite and Fatigue While Improving Blood Lipid Profiles Authors Rita R. Ellithorpe Tustin Longevity Center, Tustin, California 92780 Robert Settineri Sierra Research, Irvine, California 92606 Brett Jacques Tustin Longevity Center, Tustin, California 92780 Cyndee A. Mitchell Tustin Longevity Center, Tustin, California 92780 Garth L. Nicolson Department of Molecular Pathology, The Institute for Molecular Medicine, Huntington Beach, California 92647 DOI: https://doi.org/10.31989/ffhd.v2i1.102 Abstract Background: Lipid Replacement Therapy using NT Factor® plus kidney bean alpha-amylase inhibitor (Healthy Curb®) was used in a two month weight loss clinical trial to reduce weight and improve fatigue without changing easting or exercise patterns and without use of drugs, stimulants or herbs. Lipid Replacement Therapy Functional Food Formulation with NT Factor for Reducing Weight, Girth, Body Mass, Appetite and Fatigue While Improving Blood Lipid Profiles | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 Keywords: fatigue; food; weight
• A “PAKU-PAKU KOUBO-KUN” containing yeast and mulberry extract postprandial glycemic control in healthy Japanese men and women: a randomized, placebo-controlled, crossover study by Takizawa, Junyoo; Baba, Asami; Takara, Tsuyoshi (2023) - In 2005, he founded the electronic commerce company for health food products, MAINICHIGENKI.CO., LTD. Later in 2011, he founded the electronic commerce company for health food products, MAINICHIEGAO.CO., LTD. Keywords: food; min; paku; takara
• Protective effects of Quercus salicina blume leaves aqueous extracts against cadmium-induced oxidative stress and cell cytotoxicity in HK-2 cells by Kim, Yun Jeong; Jung, Kim Yu; Lee, Joo-Won; Om, Ae-son (2023) - Furthermore, the considerable increase in sub-G1 phase with the addition of cadmium was diminished under QS treatment indicating the ability of QS to reduce the degree of apoptosis related cell cycle phase. Conclusions: QS is a highly effective antioxidant and reduces cell cytotoxicity caused by cadmium through antioxidant functions and anti-apoptotic capabilities. Keywords: department; food
• An assessment of clinical trials used in functional food science by Marecek, Samantha; Martirosyan, Danik (2023) - In this article, we aim to achieve two major goals: the first is analyzing various types of clinical trials and the second is using this analysis to figure out which type of clinical trial is ideally suited for research related to food and nutrition.  Particularly with clinical trials used in food studies, there is an added complexity of food chemistry and food behavior as well as unique ethical issues related to clinical nutrition trials such as a potential violation of the right to be fed, disruption of food culture, and the need for food security. Keywords: food; trials
• The blockade of Artsakh causing long-term food, nutrition shortage and starvation: How functional food education can help resolve health related conditions by Williams, Kelly; Fielding, Lauren; Davis, Jessica; Martirosyan, Danik (2023) - Keywords: food shortage, Starvation, genocide,Artsakh (Nagorno-Karabakh), blockade, Berdzor (Lachin) corridor, bioactive compounds, functional foods   Downloads [Abstract] [Full Article] Published 2023-03-10 Issue Vol. 13 Although prolonged starvation has more profound impacts on the body, metabolic processes and increased stress levels can cause serious harm to someone who hasn’t consumed food for even only a few days. Keywords: artsakh; food; starvation
• Supplementation of Powdered Black Cumin (Nigella sativa) Seeds Reduces the Risk of Hypercholesterolemia by Sultan, M. Tauseef; Butt, Masood Sadiq; Ahmad, Rabia Shabeer; Batool, Rizwana; Naz, Ambreen; Suleria, Hafiz (2011) - Conclusion: Present research investigation brightened the prospects of using powdered black cumin seed in diet based therapies to improve the lipid profile. Context and purpose: The present research study was designed to expedite the role of black cumin seed in reducing the risk of hypercholesterolemia. Keywords: cumin; food; university
• Red beetroot betalains as a novel source of colorent in ice-cream as compared with Red Dye 40 (E129) by Ali, Ruaa Tariq Mohamed; Jameel, Qaswaa Yousif (2023) - Objective: The purpose of this study was to evaluate the effect of betalain (natural pigment) and red dye 40 (synthetic pigment), on the chemical, microbiological, and sensory properties of ice cream.  Materials and Methods: Betalain and red dye 40 were added into ice cream at variable concentrations of 50 mg/mL, 100 mg/mL, and 200 mg/mL. Specimens were stored for 70 days and evaluated every ten days.  Keywords: dye; food
• Spermidine content of selected dietary supplements: potential for improvement? by Steichen, Philipp; Gruber, Karin; Hippe, Berit; Haslberger, Alexander (2023) - Currently, there are ongoing proceedings regarding the novelty of a certain manufacturing process of spermidine supplements, but many other plant extracts with high spermidine content from different sources are marketed without the need for novel food authorization.  In humans, high dietary spermidine intake is associated with a lifespan increase of 5.7 years. Keywords: food; spermidine
• Food and medicinal plants from Nigeria with anti-Helicobacter pylori activities induce apoptosis in colon and gastric cancer cell lines by Lawal, Temitope O.; Patel, Shitalben R.; Mahady, Gail B. (2023) - Methods: Cancer cells were grown in appropriate media and CellTiter-Glo® 2.0 and ApoTox-Glo™ Triplex assays were used to measure cell growth and apoptosis in SW480, SW620, HCT116, Caco2 cell lines, as well as  AGS and NCI-N87 gastric cancer cells. Running Title: Inhibitory Effects of Nigerian food plants on GIT Cancers Keywords: African birch, AGS, Apoptosis, Anogeissus leiocarpus, Dillenia indica, Elephant apple, Terminalia glaucescens, Nigerian chewing sticks, HCT-116, SW480, SW620 Downloads Keywords: cancer; cells; food
• Chemical composition and effective compounds of dates and their use in a snack to give energy to athletes by Hadi, Sara Thamer; Shaban, Doaa Muthanna; Morgab, Mohammed Abd Hemed; Jasim, Safa Mohammed (2023) - Chemical composition and effective compounds of dates and their use in a snack to give energy to athletes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 8 (2023): August 2023 / Research Articles Chemical composition and effective compounds of dates and their use in a snack to give energy to athletes Authors Sara Thamer Hadi Doaa Muthanna Shaban Mohammed Abd Hemed Morgab Safa Mohammed Jasim DOI: https://doi.org/10.31989/ffhd.v13i8.1147 Abstract Background: Dates are recognized as a rich source of nutrients, so they are considered a complementary food element positioning them as functional food for athletes. Materials and Methods: Date fruits from five cultivars (Dekel Nour, Barhi, zahdi, khlas, sukari) were collected from the orchards of Baghdad Governorate. Keywords: dates; food; issn
• Effect of Poly Phenols in Enhancing the Swimming Capacity of Rats by Swamy, Mahadevappa Siddalinga; Sivanna, Naveen; Tamatam, Anand; Khanum, Farhath (2011) - No. 11 (2011): November 2011 / Research Articles Effect of Poly Phenols in Enhancing the Swimming Capacity of Rats Authors Mahadevappa Siddalinga Swamy Biochemistry and Nutrition Discipline, Defence Food Research Laboratory, Mysore-570011 Naveen Sivanna Biochemistry and Nutrition Discipline, Defence Food Research Laboratory, Mysore-570011 Anand Tamatam Biochemistry and Nutrition Discipline, Defence Food Research Laboratory, Mysore-570011 Farhath Khanum Biochemistry and Nutrition Discipline, Defence Food Research Laboratory, Mysore-570011 DOI: https://doi.org/10.31989/ffhd.v1i11.115 Abstract Background: Increased physical activities elevate reactive oxygen species (ROS) leading to dysfunction and integrity of cells thus inducing oxidative stress which intern may affect overall physical performance. In this study, the effect of selected polyphenols with established health benefits viz., catachin, chlorogenic acid, ellagic acid and quercetin was investigated with respect to swimming performance in rats. Keywords: food; issn
• Fermentation by gut microbiota cultured in a simulator of the human intestinal microbial ecosystem is improved by probiotic Enterococcus faecium CRL 183 by Sivieri, Katia; Bianchi, Fernanda; Tallarico, Maria A.; Rossi, Elizeu A. (2011) - Fermentation by gut microbiota cultured in a simulator of the human intestinal microbial ecosystem is improved by probiotic Enterococcus faecium CRL 183 | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 Conclusions: Results showed that the major effect of E. faecium CRL 183 was found in the ascendant and transverse colon.  Keywords: araraquara; food; microbiota
• Tartaric acid new derivatives as prospective and safe alternative to antimicrobials for food products packing by Mikaelyan, Aram R.; Babayan, Bella G.; Grigoryan, Armen L.; Grigoryan, Anna M.; Asatryan, Nona L.; Melkumyan, Marina A. (2024) - Search Search Register Login Home / Archives / Vol. 14 No. 1 (2024): January 2024 / Research Articles Tartaric acid new derivatives as prospective and safe alternative to antimicrobials for food products packing Authors Aram R. Mikaelyan Bella G. Babayan Armen L. Grigoryan Anna M. Grigoryan Nona L. Asatryan Marina A. Melkumyan DOI: https://doi.org/10.31989/ffhd.v14i1.1195 Abstract Introduction: Multi-drug resistance of pathogens and food spoilage bacteria is one of the most prevalent problems in contemporary science because the microbial adaptation potential is permanently being stimulated by the excessive antibiotic usage by mankind. Keywords: tartaric acid imides, tartaric acid complex aminosalts, spoilage microorganisms, antimicrobial activity, multi-drug resistance.  Keywords: food; issn; journal
• Characterization of glucose Oxidase from Penicillium chrysogenum MDC 8358: Prospects for application in food industry by Paloyan, Ani M.; Dukova, Karine G.; Hambardzumyan, Artur A. (2023) - Prospects for application in food industry Authors Ani M. Paloyan Karine G. Dukova Artur A. Hambardzumyan DOI: https://doi.org/10.31989/ffhd.v13i11.1216 Abstract Backgrounds: Food enzymes play a crucial role in enhancing specific food attributes, such as improving texture, eliminating toxins and allergens, producing carbohydrates, and enhancing flavor and appearance characteristics. Keywords:Penicillium chrysogenum MDC 8358, surface fermentation, glucose oxidase, purification, characterization, functional food preservation Downloads [Abstract] [Full Article] Published 2023-11-15 Issue Vol. 13 Keywords: food; glucose
• Comparing the FDA's process for health claim submission and the FFC's guidelines for regulating functional foods by Stratton, Sarah; Martirosyan, Danik (2023) - Compliance with regulatory guidelines, adherence to scientific standards, and clear communication of health claims contribute to a more informed and health-conscious society. Keywords: Health claims, health outcomes, regulatory requirements, functional foods, health benefits Downloads While the FDA focuses on evaluating health claims, the FFC emphasizes the safe and effective use of functional foods. Keywords: food; health
• Kombucha: Probiotic beverage or ultra-processed food: A global review using nutritional classification by Aulesa, Carlos; Gongora, Carmen (2023) - Keywords: Kombucha, Probiotic fermented food, SCOBY, Nutri-Score food classification, Nova food classification, ultra-processed food. Kombucha: Probiotic beverage or ultra-processed food: A global review using nutritional classification | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 Keywords: food; kombucha
• Dietary Supplementation of Fructooligosaccharides Reduces Hepatic Steatosis Associated with Insulin Resistance in Obese Zucker Rats by Kaume, Lydia; Gilbert, William; Gadang, Vidya; Devareddy, Latha (2011) - Key words: Dietary fiber, Fructooligosaccharide, Hepatosteatosis, Liver lipids, Non-alcoholic fatty liver disease (NAFLD), Zucker. Gravimetric quantification of liver lipids was performed and peroxisome proliferator-activated receptor-γ (PPAR-γ) gene expression was determined in white adipose tissue by qRT-PCR. Keywords: food; fos
• A Nutritional Approach to the Metabolic Syndrome by Lerman, Robert H. (2011) - The modified Mediterranean diet with medical food was superior in reducing markers of MetS and CVD risk. At the completion of the study, 43% of participants receiving medical food and phytochemicals exhibited net resolution of MetS compared with only 22% of those on diet and exercise alone. Keywords: food; issn
• Strategic food reserves storage, safety and risk minimization: Problems and perspectives by Shahinyan, Samvel; Badasyan, Ani; Babayan, Bella; Melkumyan, Marina; Yesayan, Tigran; Yesayan, Alexander (2024) - Keywords: Magellan Cave (Magill cave), underground constructions, food strategic reserve storage, biological safety, spoilage, psychrophilic microbes Downloads Results: The preliminary results from Magellan Cave (Magill Cave) in the Areni region of the Republic of Armenia indicate that the cave has suitable conditions for use as a potential site for strategic food storage, particularly for cereal grains. Keywords: cave; food; storage
• The epigenetic impact of daily diet food choices on human health and chronic diseases by Yesayan, Alexander; Chetta, Massimiliano; Babayan, Bella; Yesayan, Tigran A. Yesayan; Esoyan, Syuzanna; Sevoyan, Garegin (2024) - Thus, dietary treatments may provide an epigenetic regulation, emphasizing nutrition role in preserving health and preventing illness via epigenetics Keywords: human epigenetics, epigenetic regulation of diseases, daily food ration, healthy food Downloads [Abstract] [Full Article] Published 2024-10-25 Issue Vol. 14 No. 10 (2024): October 2024 Section Research Articles License Copyright (c) 2024 Functional Foods in Health and Disease This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. The epigenetic impact of daily diet food choices on human health and chronic diseases | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 Keywords: food; issn
• The Safety of Animal-derived Food Products in Areas of Technogenic Pollution by Sevoyan, Garegin; Minasyan, Seyran; Yesayan, Tigran; Babayan, Bella; Avetisyan, Syuzanna; Yesayan, Alexander (2024) - Keywords: food safety, animal-sourced food, heavy metals, technogenic pollution, remediation. Although the detected levels are below the maximum permissible concentrations established by the World Health Organization (WHO), continuous monitoring of heavy metal concentrations in this area is recommended to mitigate potential health risks associated with chronic consumption of locally produced eggs.  Keywords: animal; concentrations; food
• Rose hip (Rosa canina L): A functional food perspective by Fan, Cui; Pacier, Callen; M. Martirosyan, Danik (2014) - Rose hip (Rosa canina L): A functional food perspective | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 4 No. 12 (2014): December 2014 / Review Articles Rose hip (Rosa canina L): A functional food perspective Authors Cui Fan Functional Food Center/Functional Food Institute, Dallas, TX, USA Callen Pacier Functional Food Center/Functional Food Institute, Dallas, TX, USA Danik M. Martirosyan Functional Food Center/Functional Food Institute, Dallas, TX, USA DOI: https://doi.org/10.31989/ffhd.v4i12.159 Abstract Background: Rose hip (Rosa canina L.) is the pseudo-fruit of the rose plant, which is widely known as a valuable source of polyphenols and vitamin C. Both in vivo and in vitro studies have demonstrated that this fruit exhibits anti-inflammatory, antioxidant, and antiobesogenic activities. The health benefits of Rose hip (RH) have been attributed to its wide range of bioactive compounds including the anti-inflammatory galactolipid: (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O- β-D-galactopyranosyl glycerol (GOPO), vitamin C, phenolics, lycopene, lutein, zeaxanthin, and other carotenoids. Keywords: food; issn
• Antimicrobial zein/glucomannan edible films with pomegranate polyphenols and meadow sage essential oil for enhanced food preservation by Ismoilov, Ikromjon; Yuldasheva, Durdona; Kodirova, Gulru; Bobokalonov, Jamshed; Muhidinov, Zayniddin; Liu, LinShu (2025) - Natural polymers, such as proteins and polysaccharides, are widely used to develop edible films with favorable mechanical strength and gas barrier properties. Keywords: glucomannan, zein, edible films, polyphenols, essential oils, antibacterial activity. Keywords: films; food; issn
• Algal biomass as a food and feed supplement: Process engineering analysis by Harutyunyan, Baghish; Mühlstädt, Gunnar; Seibel, Leander; Hilpmann, Gerd; Sayadyan, Angelina; Aghabekyan, Ani; Zakoyan, Anna; Khachatryan, Gayane; Hovhannisyan, Ruzanna; Stepanyan, Tamara; Harutyunyan, Seda; Goginyan, Vigen (2025) - Conclusion: Near-infrared spectroscopy has proven to be an effective method for non-destructive biomass analysis. Novelty: The study uniquely integrates comparative biochemical profiling of algal and cyanobacterial biomass with a cost-efficiency analysis of semi-industrial biomass production. Keywords: biomass; food; issn
• Nodule bacteria and cyanobacterial symbionts: Biological drivers of sustainable crop production and healthy nutrition by Harutyunyan, Seda; Khachatryan, Gayane; Stepanyan, Tamara; Goginyan, Vigen (2025) - Nodule bacteria and cyanobacterial symbionts: Biological drivers of sustainable crop production and healthy nutrition | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 10 (2025): October 2025 / Research Articles Nodule bacteria and cyanobacterial symbionts: Biological drivers of sustainable crop production and healthy nutrition Authors Seda Harutyunyan Gayane Khachatryan Tamara Stepanyan Vigen Goginyan DOI: https://doi.org/10.31989/ffhd.v15i10.1718 Abstract Background: Chemical fertilizers negatively impact soil health and biodiversity, highlighting the urgent need for sustainable biological alternatives. Total yield rose by as much as 67%, highlighting the strong synergistic potential of microbial consortia for sustainable crop production and nutritionally enriched food sources. Keywords: bacteria; food; nodule
• Water-soluble low-molecular-weight b-(1, 3–1, 6) D-Glucan inhibit cedar pollinosis by Jippo, Tomoko; Suzuki, Toshio; Sato, Harumi; Kobayashi, Yuko; Shigekawa, Munekazu (2015) - Water-soluble low-molecular-weight b-(1, 3–1, 6) D-Glucan inhibit cedar pollinosis | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 2 (2015): February 2015 / Short Report Water-soluble low-molecular-weight b-(1, 3–1, 6) D-Glucan inhibit cedar pollinosis Authors Tomoko Jippo Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University, 5-25-1 Fujishirodai, Suita, Osaka 565-0873, Japan; Toshio Suzuki Department of Applied Chemistry and Bioengineering, Graduate School of Engineering, Osaka City University, Sugimoto 3-3-138, Sumiyoshi-ku, Osaka 558-8585, Japan Harumi Sato Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University, 5-25-1 Fujishirodai, Suita, Osaka 565-0873, Japan; Yuko Kobayashi Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University, 5-25-1 Fujishirodai, Suita, Osaka 565-0873, Japan; Munekazu Shigekawa Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University, 5-25-1 Fujishirodai, Suita, Osaka 565-0873, Japan; DOI: https://doi.org/10.31989/ffhd.v5i2.173 Abstract Background: The incidences of allergenic diseases such as allergenic rhinitis, atopic dermatitis, asthma, and food allergies have increased in several countries. Mast cells have critical roles in various biological processes related to allergenic diseases. Keywords: food; glucan
• Anti-type 2 diabetes mellitus activity of Citrus reticulata-derived materials: Mechanistic insights from integrated network pharmacology, molecular docking, and in vitro assays by Wang, Hanhua; Li, Mingyue; Wang, Yanyue (2025) - Novelty: This study is the first to integrate multi-approach validation—combining in vitro bioactivity, network pharmacology, molecular docking, and ADMET profiling—to systematically reveal that CRDMM exerts anti-T2DM effects via a multi-component, multi-target mechanism.  Anti-type 2 diabetes mellitus activity of Citrus reticulata -derived materials: Mechanistic insights from integrated network pharmacology, molecular docking, and in vitro assays | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: food; issn
• Modulation of Protein Quality Control Systems as Novel Mechanisms Underlying Functionality of Food Phytochemicals by Ohnishi, Kohta; Irie, Kazuhiro; Murakami, Akira (2013) - Many recent studies have indicated that protein quality control (PQC) systems play key roles in counteracting ‘proteo-stress’, which is comprised of several processes, including protein refolding by heat shock proteins (HSPs) and degradation of abnormal proteins by the ubiquitin-proteasome system as well as autophagy. Objective: Phytochemicals are xenobiotics, thus their biochemical interactions with animal proteins are considered to occur in a non-specific manner, which raises the possibility that some phytochemicals cause proteo-stress for activating PQC systems. Keywords: food; phytochemicals; systems; zer
• Nutritional Proteomics: Investigating molecular mechanisms underlying the health beneficial effect of functional foods by Kawashima, Yusuke; Singh, Anil; Kodera, Yoshio; Matsumoto, Hiroyuki (2013) - We wish to develop nutritional proteomics to promote a new area in functional food studies for a better understanding of the role of functional foods in health and disease. Keywords: Nutritional proteomics, functional foods, mass spectrometry, genome database, cellular signaling, omega-3 and omega-6 polyunsaturated fatty acids Downloads Keywords: food; health; proteomics
• Producing micron- and nano-size formulations for functional foods applications by Panagiotou, Thomai; Fisher, Robert J. (2013) - The goal is to develop large scale manufacturing systems that implement efficient platform technologies, with their respective operational maps, to produce functional food formulations, with particle sizes of these specially formulated nutraceutical ingredients in the micron-and nano- range. Objective: Demonstrating that stable micron- and nano-size emulsions, liposomes, and aqueous suspensions of functional food formulations can be produced using both “top down” and “bottom up” methods is our main objective. Keywords: food; formulations; processing; size
• Astaxanthin as a Medical Food by Yamashita, Eiji (2013) - Various important benefits to date have suggested for human health such as immunomodulation, anti-stress, anti-inflammation, LDL cholesterol oxidation suppression, enhanced skin health, improved semen quality, attenuating eye fatigue, sport performance and endurance, limiting exercised induced muscle damage, suppressing the development of life-style related diseases such as obesity, atherosclerosis, diabetes, hyperlipidemia and hypertension. Nowadays, the research and demand for natural astaxanthin in human health application are explosively growing worldwide. Keywords: astaxanthin; food; issn
• Impact of dietary intervention with a functional food supplement to combat anemia - the blood iron metabolic disorder among the coffee plantation laborers by Rani, Vasantha Esther; Paulraj, Samuel (2013) - The outcome of this study on the dietary intervention, based on nutritional picture of coffee plantation laborers, will have a nationwide application because of the simplified, stable coffee plantation operations throughout India. Impact of dietary intervention with a functional food supplement to combat anemia - the blood iron metabolic disorder among the coffee plantation laborers | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 Keywords: food; intervention; iron
• “Weak direct” and “Strong indirect” interactions are the mode of action of food factors by Konishi, Tetsuya (2014) - In this article, the functional properties of food factors and drugs are comparatively reviewed and the characteristic features of food factor function is discussed, based on the idea of “weak direct” and “strong indirect” actions of food factors to their receptors. “Weak direct” and “Strong indirect” interactions are the mode of action of food factors | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: food; issn
• Content validity and reliability of a food frequency questionnaire to measure eicosapentaenoic acid and docosahexaenoic acid intakes in young adults: A pilot study by Hanson, Jennifer A.; Rosenkranz, Richard R.; Holcomb, Carol Ann; Haub, Mark D. (2012) - Keywords: Functional foods, n-3 fatty acids, dietary assessment, seafood, eicosapentaenoic acid, docosahexaenoic acid Downloads The purpose of this pilot study was to assess the content validity and reliability of a novel 14-item food frequency questionnaire (FFQ) designed to measure contemporary sources of eicosapentaenoic aid (EPA) and docosahexaenoic acid (DHA). Keywords: acid; food; reliability
• Angiotensin-converting enzyme inhibitory effects of dairy- and soy-derived peptides in pre-hypertensive overweight men and women by Munn, Melissa S.; Sibley, Shalamar; Brundage, Richard; Ismail, Baraem; Earthman, Carrie P. (2013) - Conclusions: The results of this pilot study support a discrepancy between in vitro and human-based in vivo ACE-inhibitory acute effects of whey and soy protein hydrolysates, underscoring the need for further research to better understand potential explanations for these findings.    Findings: Using a randomized crossover design, four initial subjects received five treatments (unhydrolyzed casein, whey protein isolate, whey protein hydrolysate, soy protein isolate, soy protein hydrolysate) at different testing visits separated by three-day washout periods. Keywords: food; protein; soy
• Can functional foods reduce the risk of disease? Advancement of functional food definition and steps to create functional food products by Martirosyan, Danik; Kanya, Hunter; Nadalet, Camila (2021) - Advancement of functional food definition and steps to create functional food products | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Keywords: functional foods, bioactive compounds, biomarkers, functional food science, functional food products, epidemiological studies Downloads Keywords: ffc; food
• Marketing strategies for functional food products by Chen, Stella; Martirosyan, Danik (2021) - Marketing strategies for functional food products | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Of the 15 steps the Functional Food Center has outlined for development of functional food products, marketing a product to educate people is closely related to consumer acceptance and is therefore an important step to study to increase success of functional food products. Keywords: food; issn
• Effect of 12 weeks of continuous burdock sprout extract intake on oxidized LDL: A placebo-controlled, randomized, double-blind, parallel-groups study by Ito, Naohito; Ohno, Akiko; Yomoda, Satoshi; Inamasu, Satoshi; Hattori, Hiroki; Nishihira, Jun (2021) - No. 9 (2021): September 2021 / Research Articles Effect of 12 weeks of continuous burdock sprout extract intake on oxidized LDL: A placebo-controlled, randomized, double-blind, parallel-groups study Authors Naohito Ito Hokkaido Information University Akiko Ohno R&D Innovation Group, Corporate Planning Division, Kracie Holdings Satoshi Yomoda R&D Innovation Group, Corporate Planning Division, Kracie Holdings Satoshi Inamasu R&D Innovation Group, Corporate Planning Division, Kracie Holdings Hiroki Hattori Hokkaido Information University Jun Nishihira Hokkaido Information University DOI: https://doi.org/10.31989/ffhd.v11i9.820 Abstract Background: Arctigenin, a lignan polyphenol found in burdock sprout, is a potent activator of AMP-activated protein kinase (AMPK) and has beneficial effects on metabolic disorders in mice. Clinical trial registration: UMIN000036664 Keywords: arctigenin, burdock sprout, oxidized LDL, FIB-4 index, randomized controlled study Author Biography Jun Nishihira, Hokkaido Information University President, Professor Downloads Keywords: burdock; food; sprout
• Functional food science: Differences and similarities with food science by Martirosyan, Danik; von Brugger, Jessica; Bialow, Sarina (2021) - The field of functional food science (FFS) has been introduced to combat this. Functional foods are foods with added bioactive compounds which provide a clinically proven health benefit. Keywords: food; science
• Review on physicochemical, medicinal and nutraceutical properties of poppy seeds: a potential functional food ingredient by Muhammad, Aleem; Akhtar, Aqsa; Aslam, Sadia; Khan, Rao Sanaullah; Ahmed, Zaheer; Khalid, Nauman (2021) - Review on physicochemical, medicinal and nutraceutical properties of poppy seeds: a potential functional food ingredient | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 No. 10 (2021): October 2021 / Review Articles Review on physicochemical, medicinal and nutraceutical properties of poppy seeds: a potential functional food ingredient Authors Aleem Muhammad Punjab Food Authority, Lahore Aqsa Akhtar School of Food and Agricultural Sciences, University of Management and Technology, Lahore, Punjab, Pakistan Sadia Aslam School of Food and Agricultural Sciences, University of Management and Technology, Lahore, Punjab, Pakistan Rao Sanaullah Khan School of Food and Agricultural Sciences, University of Management and Technology, Lahore, Punjab, Pakistan Zaheer Ahmed Department of Home and Health Sciences, Allama Iqbal Open University, Islamabad, Pakistan Nauman Khalid School of Food and Agricultural Sciences, University of Management and Technology, Lahore, Punjab, Pakistan DOI: https://doi.org/10.31989/ffhd.v11i10.836 Abstract The poppy seed plant (Papaver somniferum L.) is well known for its health benefits. Keywords: food; issn; poppy
• Effect of combining sleep-promoting food intake and electric field application on sleep in healthy participants: A pilot study by Nedachi, Takaki; Haketa, Kaoru; Harakawa, Shinji; Miura, Naoki; Wakame, Koji (2021) - Thus, this study aimed to investigate the cointervention effect of sleep-promoting functional food intake and EF application on sleep quality in healthy participants.  Conclusions: Food mixture containing known sleep-promoting ingredients such as GABA and lafma can improve sleep quality, and the improvement effect can be enhanced when administered in combination with an EF. Keywords: electric field therapy, Kumasasa (Sasa senanensis), electric fields, sleep quality, electroencephalography Clinical trial registration: Keywords: food; sleep
• Lowbush blueberries, Vaccinium angustifolium, modulate the functional potential of nutrient utilization and DNA maintenance mechanisms in the rat proximal colon microbiota by Lacombe, Alison; Li, Robert W.; Klimis-Zacas, Dorothy; Kristo, Aleksandra S.; Tadepalli, Shravani; Krauss, Emily; Young, Ryan; Wu, Vivian C. H. (2012) - Functional profiles and metabolic potential of the colon microbiota in response to diet were analyzed using deep whole genome sequencing (WGS). This study helps unravel diverse mechanisms of microbial adaptation to LWBs in the diet of mammals and can provide guidance in optimizing functional diets. Keywords: food; hall; maine; university
• Phenotype microarray profiling of the antibacterial activity of red cabbage by Abu Bakar, F.; Hafidh, R. R.; Abdulamir, A. S. (2012) - Moreover, extracts of functional food can exert antibacterial activity by hitting a wide range of metabolic pathways, at the same time leading to very difficult condition for bacteria to rapidly develop resistance. Phenotype microarray profiling of the antibacterial activity of red cabbage | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 6 (2012): June 2012 / Research Articles Phenotype microarray profiling of the antibacterial activity of red cabbage Authors F. Abu Bakar Insititute of Bioscience, University Putra Malaysia, Serdang R. R. Hafidh Microbiology Department, College of Medicine, Baghdad University A. S. Abdulamir Insititute of Bioscience, University Putra Malaysia, Serdang DOI: https://doi.org/10.31989/ffhd.v2i6.88 Abstract Background: Functional food can be a potent source of wide array of biocomonents with antimicrobial activity. Keywords: activity; food; issn
• Effect of incorporating plant-based quercetin on physicochemical properties, consumer acceptability and sensory profiling of nutrition bars by Bansal, Uma; Bhardwaj, Aastha; Singh, Som Nath; Khubber, Sucheta; Sharma, Nitya; Bansal, Vasudha (2022) - Effect of incorporating plant-based quercetin on physicochemical properties, consumer acceptability and sensory profiling of nutrition bars | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 3 (2022): March 2022 / Research Articles Effect of incorporating plant-based quercetin on physicochemical properties, consumer acceptability and sensory profiling of nutrition bars Authors Uma Bansal Research Scholar (Ph.D), Dept. of Food Technology, Jiwaji University, Madhya Pradesh, India Aastha Bhardwaj Lecturer, Dept. of Food Technology, Jamia Hamdard New Delhi, India Som Nath Singh Scientist ‘F”, DRDO - Defence Institute of Physiology and Allied Sciences (DIPAS), Delhi, India Sucheta Khubber Scientist II, General Mills, Mumbai, India Nitya Sharma Post-Doctoral Fellow, Centre for Rural Development & Technology, Indian Institute of Technology (IIT), New Delhi, India Vasudha Bansal Government Home Science College, Sector-10, Affiliated to Panjab University, Chandigarh, India DOI: https://doi.org/10.31989/ffhd.v12i3.888 Abstract Abstract Background: Plant-based quercetin is usually produced using fruit and vegetable wastes and is sold in the market in powdered form. With the increase in the quercetin content, a significant decrease in the water activity and increase in the lightness (L*) and hardness values of nutrition bar samples was observed. Keywords: food; india; quercetin; technology
• Development of functional food products in relation to obesity by Choudhary, Monika; Grover, Kiran (2012) - Development of functional food products in relation to obesity | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 6 (2012): June 2012 / Review Articles Development of functional food products in relation to obesity Authors Monika Choudhary Department of Food and Nutrition, College of Home Science, Punjab Agricultural University, Ludhiana, 141004 Kiran Grover Department of Food and Nutrition, College of Home Science, Punjab Agricultural University, Ludhiana, 141004 DOI: https://doi.org/10.31989/ffhd.v2i6.90 Abstract The development of new eating habits, as well as actual trends in production and consumption, has a health, environmental and social impact. Keywords: food; issn
• Anti-allergic activity of an ethanol extract of bunching onion (Allium fistulosum), a traditional vegetable from Osaka by Jippo, Tomoko; Kobayashi, Yuko; Kitada, Kosuke; Kitsuda, Koji (2022) - Conclusion: An Osakan traditional vegetable, bunching onion (Allium fistulosum), exhibited anti-allergic activity, and should be explored further as a possible treatment for allergic diseases. Anti-allergic activity of an ethanol extract of bunching onion (Allium fistulosum), a traditional vegetable from Osaka | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 3 (2022): March 2022 / Research Articles Anti-allergic activity of an ethanol extract of bunching onion (Allium fistulosum), a traditional vegetable from Osaka Authors Tomoko Jippo Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University Yuko Kobayashi Department of Food and Nutrition, Faculty of Human Life Sciences, Senri Kinran University Kosuke Kitada Research Institute of Environment, Agriculture and Fisheries, Osaka Prefecture Koji Kitsuda Research Institute of Environment, Agriculture and Fisheries, Osaka Prefecture DOI: https://doi.org/10.31989/ffhd.v12i3.900 Abstract Introduction: The incidences of allergic diseases such as allergic rhinitis, atopic dermatitis, asthma, and food allergies are rising in developed countries. Keywords: food; issn; osaka
• Effect of inoculation of Lactobacillus acidophilus on the level of nitrite and nitrate in yogurt containing spinach during refrigeration in 21 days by Keshavarz, Mitra; Barati-Boldaji, Reza; Mazloomi, Seyed Mohammad; Yousefi, Mohammad Hashem (2022) - Effect of inoculation of Lactobacillus acidophilus on the level of nitrite and nitrate in yogurt containing spinach during refrigeration in 21 days | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 4 (2022): April 2022 / Research Articles Effect of inoculation of Lactobacillus acidophilus on the level of nitrite and nitrate in yogurt containing spinach during refrigeration in 21 days Authors Mitra Keshavarz Department of Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran Reza Barati-Boldaji Department of Nutrition, School of Nutrition and Food Sciences, Nutrition and Food Sciences Research, Center Shiraz University of Medical Sciences, Shiraz, Iran Seyed Mohammad Mazloomi Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Nutrition and Food Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad Hashem Yousefi Department of Food Hygiene and Public Health, Faculty of Veterinary Medicine, Shiraz University, Shiraz, Iran DOI: https://doi.org/10.31989/ffhd.v12i4.907 Abstract Introduction: Yogurt is mixed with spinach in some countries. Keywords: food; sciences
• Nutritional and anti-gastro ulcerative role of the gum Arabic (Acacia senegal L.) compared to a reference drug by Yousif Jameel, Qaswaa; Abdullah Ajeel, Mohammed; Khairullah Mohammed, Nameer (2022) - As alcohol consumption increases, ethanol impacts ulcers as a factor that causes stomach mucosal invasion, which leads to stomach ulcers. Conclusion: These findings demonstrate that GA plays a protective role toward gastric mucosal injury in rats induced by ethanol, which in turn reduced the inflammatory response, and significantly reduced the hemorrhagic gastric lesions and the pH of the gastric contents.   Keywords: food; issn; stomach
• Chemical composition of water buffalo milk and its low-fat symbiotic yogurt development by Han, Xue; Lee, Frank L.; Zhang, Lanwei; Guo, M. R. (2012) - While typical average milk compositions are readily available, information on seasonal variation in chemical composition of buffalo milk is limited -especially in the Northeastern region of the United States. Data collected in this study can be useful for the manufacture of a wide variety of specialty dairy products such as symbiotic buffalo milk yogurt. Keywords: buffalo; food; milk
• Evaluation of dietary Intake and Food Patterns of Adolescent Girls in Sistan and Baluchistan Province, Iran by Montazerifar, Farzaneh; Karajibani, Mansour; Dashipour, Ali Reza (2012) - Results: The analysis of dietary intakes showed that energy, calcium, zinc, vitamin C and folate intake, compared to the Dietary Reference Intake (DRI), were found to be lower. Objective: This study assessed the dietary intake and habits of high school girls in Sistan and Bluchistan province, in southeastern Iran. Keywords: food; intake
• A review of the health benefits of Strychnos decussata (Pappe) Gilg (Loganiaceae): a potential functional food by Maroyi, Alfred (2022) - S. decussata has diverse uses as a food plant and also has medicinal uses such as charm and ritual, scorpion and snake bite antidote, ethnoveterinary medicine, and traditional medicine for fever, gastro-intestinal problems, headache, respiratory infections, wounds, venereal diseases and infections. A critical appraisal of the medicinal, pharmacological and socio-economic properties of S. decussata are provided. Keywords: decussata; food
• Preclinical study of goat milk kefir as an antihyperglycemic food by Susanti, Siti; Nurwantoro, Nurwantoro; Elto, Jessen Juan; Nugroho, Trilaksana; Suryani, Ade Erma; Rizqiati, Heni (2022) - This study compared goat milk kefir products to other processed milk products considered to be capable of controlling and reducing blood sugar levels.  Objective:This study aimed to compare goat milk kefir products to other processed food products considered to be capable of controlling and reducing blood sugar levels. Keywords: agriculture; blood; food

• The effect of daily peanut consumption on cognitive function and indicators of mental health among healthy young women by Reeder, Nicole; Tolar-Peterson, Terezie; Adegoye, Grace A.; Dickinson, Erin; McFatter, Emily (2022) - The effect of daily peanut consumption on cognitive function and indicators of mental health among healthy young women | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 12 (2022): December 2022 / Research Articles The effect of daily peanut consumption on cognitive function and indicators of mental health among healthy young women Authors Nicole Reeder Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, Mississippi, 39762, USA http://orcid.org/0000-0002-7392-5464 Terezie Tolar-Peterson Department of Health Science and Human Ecology, California State University San Bernardino, San Bernardino, California, 92359 Grace A. Adegoye Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, Mississippi, 39762, USA Erin Dickinson Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, Mississippi, 39762, USA Emily McFatter Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, Mississippi, 39762, USA DOI: https://doi.org/10.31989/ffhd.v12i12.1010 Abstract Background: Peanuts and tree nuts contain many bioactive compounds that may provide health benefits. Methods:This was a pre-post test study of 65 women (n = 32 in peanut group, n = 29 in control group). Keywords: health; mississippi state; state university
• Health Promotion by Antioxidants by Nishino, Hoyoku; Murakoshi, Michiaki; Satomi, Yoshiko (2011) - Key words: beta-Cryptoxanthin, Health promotion, Liver cancer prevention, Prevention of alcohol-induced gamma-GTP elevation, Prevention of obesity. Health Promotion by Antioxidants | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 Keywords: health; issn
• Reproductive health-promoting effects of functional foods by Kayode, Omowumi; Ohanaka, Nkechinyere J.; Kolawole, Ikeoluwa O.; Afolabi, Olatayo A.; Iyobhebhe, Matthew E. (2023) - Reproductive health-promoting effects of functional foods | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 9 (2023): September 2023 / Review Articles Reproductive health-promoting effects of functional foods Authors Omowumi Kayode Nkechinyere J. Ohanaka Ikeoluwa O. Kolawole Olatayo A. Afolabi Matthew E. Iyobhebhe DOI: https://doi.org/10.31989/ffhd.v13i9.1130 Abstract Functional foods are foods that, in addition to providing basic nutrients, have health-promoting effects when ingested consistently over a period of time. Oxidative stress-related infertility can be managed by functional foods rich in antioxidants and other phytochemicals with modulatory effects on reproductive tissues. Keywords: foods; health
• The effect of daily peanut consumption on indicators of metabolic health among healthy young women by Reeder, Nicole; Tolar-Peterson, Terezie; Adegoye, Grace A.; Dickinson, Erin; McFatter, Emily (2023) - The effect of daily peanut consumption on indicators of metabolic health among healthy young women | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 12 (2023): December 2023 / Research Articles The effect of daily peanut consumption on indicators of metabolic health among healthy young women Authors Nicole Reeder http://orcid.org/0000-0002-7392-5464 Terezie Tolar-Peterson Grace A. Adegoye Erin Dickinson Emily McFatter DOI: https://doi.org/10.31989/ffhd.v13i12.1193 Abstract Background:Regular consumption of nuts and peanuts may reduce the risk of cardiovascular disease due to the bioactive compounds found within them. Further research is needed to fully elucidate the effect of peanut consumption on indicators of cardiovascular health in different populations.  Keywords: health; issn
• A comparison of the gene expression profiles and pathway network analyses after treatment of Prostate cancer cell lines with different Ganoderma lucidum based extracts by Kao, Chi H.J.; Bishop, Karen S; Han, Dug Yeo; Murray, Pamela M; Glucina, Marcus P.; Marlow, Gareth J.; Ferguson, Lynnette R (2014) - G. lucidum grows under conditions which range from tropical to temperate and has a different physiology depending on the geographical region in which it is grown. A comparison of the gene expression profiles and pathway network analyses after treatment of Prostate cancer cell lines with different Ganoderma lucidum based extracts | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: auckland; health; university
• Functional food availability, a limitation to peoples’ health on Islands by Kramadhati, Rameshwar; Dinh, Tuyetha; Mekamkwe, Judith; Ndungu, Patrick; Nguyen, Erick (2011) - Food availability 2. Results: All the foods were imported and the time taken for the food (including protective foods) to reach the island was about 3 weeks. Keywords: foods; health; plaza juliana
• Synbiotic-supplemented organic formula enhances infant gut health: a randomized controlled trial by Sheng, Xiaoyang; Gu, Zhendong; Li, Xuelian; Ni, Jiayi (2025) - Methods: Seventy-five healthy full-term infants were enrolled and divided equally into three groups: breastfeeding, organic protein milk formula, and organic protein milk with BB-12® and prebiotics DiGenix® formula. Novelty of the study: This study is among the first randomized controlled trials comparing organic protein milk formula enriched with Bifidobacterium animalis subsp. Keywords: health; milk
• Protein hydrolysates and recovery of muscle damage following eccentric exercise by M.J, Dale; R.L, Thomson; A.M, Coates; P.R.C, Howe; A, Brown; J.D, Buckley (2015) - Protein hydrolysates and recovery of muscle damage following eccentric exercise | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 1 (2015): January 2015 / Research Articles Protein hydrolysates and recovery of muscle damage following eccentric exercise Authors Dale M.J Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research and School of Health Sciences, University of South Australia, Adelaide, Australia; Thomson R.L Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research and School of Health Sciences, University of South Australia, Adelaide, Australia; Coates A.M Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research and School of Health Sciences, University of South Australia, Adelaide, Australia; Howe P.R.C Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research and School of Health Sciences, University of South Australia, Adelaide, Australia; Clinical Nutrition Research Centre, University of Newcastle, Newcastle, Australia; Brown A Murray Goulburn Co-operative Co. Ltd, Melbourne, Australia Buckley J.D Alliance for Research in Exercise, Nutrition and Activity (ARENA), Sansom Institute for Health Research and School of Health Sciences, University of South Australia, Adelaide, Australia; DOI: https://doi.org/10.31989/ffhd.v5i1.164 Abstract Background: A whey protein hydrolysate (NatraBoost XR; WPHNB) has been shown to speed repair muscle damage. Isometric knee extensor strength was measured in 39 sedentary male participants before and after 100 maximal eccentric contractions of the knee extensors to induce muscle damage. Keywords: australia; health; research
• European Health Claims for Small and Medium-Sized Companies – Utopian Dream or Future Reality? by Brandenburger, Sonja; Birringer, Marc (2015) - Keywords: health claims, European Legislation, SME Downloads [Abstract] [Full Article] Untitled Published 2015-02-11 Issue Vol. 5 No. 2 (2015): February 2015 Section Review Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Nevertheless, health claims for small and medium-sized enterprises will inevitably be the future to keep the European food and drink market competitive. Keywords: claims; health
• Apricot leaf: A new source of bioactive compounds – an overview by Grigoryan, Anna; Hanisyan, Ruzanna; Mirzoyan, Varsik (2025) - Objectives: This review summarizes current knowledge on the biochemical composition, phytochemical diversity, and health-promoting effects of apricot leaves, highlighting their potential applications in functional foods and natural health products. Keywords: apricot leaves, bioactive compounds, functional food, bioactive properties, applications in functional Downloads [Abstract] [Full Article] Published 2025-10-15 Issue Vol. 15 Keywords: apricot; health; leaves
• Anti-atherosclerotic effects of konjac by Yanai, Hidekatsu; Adachi, Hiroki; Katsuyama, Hisayuki; Hamasaki, Hidetaka; Sako, Akahito (2015) - Anti-atherosclerotic effects of konjac | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 4 (2015): April 2015 / Review Articles Anti-atherosclerotic effects of konjac Authors Hidekatsu Yanai Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan Hiroki Adachi Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan Hisayuki Katsuyama Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan Hidetaka Hamasaki Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan Akahito Sako Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba, Japan DOI: https://doi.org/10.31989/ffhd.v5i4.178 Abstract Definition: The Konjac plant comes from the genus Amorphophallus. Here, we reviewed possible anti-atherosclerotic effects of konjac, using the search Pubmed ®. Keywords: health; medicine
• Inhibition of atherosclerotic plaque formation in ApoE-deficient mice by dietary supplementation with Lactobacillus casei by Tang, Zhihong; Ma, Jing; Zeng, Zhen; Wu, Siping; Hou, Mengjun (2014) - Addition of lactobacillus casei also ameliorated serum lipid profile by decreasing total serum cholesterol and increasing HDL cholesterol concentration. Lactobacillus casei has been demonstrated to have the potential to reduce human serum cholesterol levels. Keywords: casei; health
• Functional Foods and Active molecules with relevance to Health and Chronic disease by Martins, Ian James (2017) - https://doi.org/10.31989/ffhd.v7i10.387 Keywords: calorie sensitive gene, nutrition, mitophagy, senescence, active biomolecules, diabetes, functional foods, caffeine, chronic disease EDITORIAL In recent years, food scientists have published several articles which state how functional foods contain known, effective biologically-active compounds Nutritional science provides functional foods with the required amount of natural antioxidants, vitamins, fats, proteins, carbohydrates, and other components required to maintain the immune system and for the survival of cells [4-6]. Keywords: diabetes; disease; foods; health; martins
• Chemoprevention of HBV-related hepatocellular carcinoma by the combined product of resveratrol and silymarin in transgenic mice by Hsieh, Wen-Chuan; Yang, Ching-Wen; Haung, Yi-Sheng; Chao, Ting-Wei; Tsai, Tin-Fen; Su, Ih-Jen (2013) - No. 9 (2013): September 2013 / Research Articles Chemoprevention of HBV-related hepatocellular carcinoma by the combined product of resveratrol and silymarin in transgenic mice Authors Wen-Chuan Hsieh National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan Ching-Wen Yang Institute of Basic Medical Research, National Cheng Kung University Medical School, Tainan Yi-Sheng Haung National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan Ting-Wei Chao National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan Tin-Fen Tsai Faculty of Life Sciences and Institute of Genetics, National Yang-Ming University, Taipei Ih-Jen Su National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan DOI: https://doi.org/10.31989/ffhd.v3i9.41 Abstract Background: Patients with chronic hepatitis B virus (HBV) infection are at a high risk to develop hepatocellular carcinoma (HCC). Conclusions: The combined silymarin and resveratrol product exhibits a synergistic effect on the reduction of HCC development in transgenic mice model and may represent a potential agent for the prevention of HCC in high risk chronic HBV carriers. Keywords: hbv; health; national
• The Potential Anti Helicobacter pylori and antioxidant effects of Artemisia Judaica by El-Sayed, M. Adel; BaAbbad, Radwan; Balash, Amal; Al-Hemdan, Nasser A.; Softah, Abdullah (2013) - The Potential Anti Helicobacter pylori and antioxidant effects of Artemisia Judaica | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 9 (2013): September 2013 / Research Articles The Potential Anti Helicobacter pylori and antioxidant effects of Artemisia Judaica Authors M. Adel El-Sayed Pharmacology department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA Radwan BaAbbad Medical Microbiology departments, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA Amal Balash Biochemistry department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA Nasser A. Al-Hemdan Community Medicine department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA Abdullah Softah Undergraduate Medical Student, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA DOI: https://doi.org/10.31989/ffhd.v3i9.42 Abstract Artemisia judaica (AJ) is one of the common species of the genus Artemisia that grows in Saudi Arabia desert and Sinai, Egypt where animals graze on it. (AJ) has anthelmintic, antibacterial, antiinflammatory, analgesic and antipyretic effects. Keywords: abdulaziz; health; king
• Effect of grape seed extract on postprandial oxidative status and metabolic responses in men and women with the metabolic syndrome - randomized, cross-over, placebo-controlled study by Edirisinghe, Indika; Randolph, Jody; Cheema, Mandeep; Tadapaneni, Ravi; Park, Eunyoung; Burton-Freeman, Britt; Kappagoda, Tissa (2013) - This investigation was undertaken to determine whether a grape seed extract (GSE) that is rich in mono-, oligo- and poly- meric polyphenols would modify postprandial oxidative stress and inflammation in individuals with the metabolic syndrome (MetS). Search Search Register Login Home / Archives / Vol. 2 No. 12 (2012): December 2012 / Research Articles Effect of grape seed extract on postprandial oxidative status and metabolic responses in men and women with the metabolic syndrome - randomized, cross-over, placebo-controlled study Authors Indika Edirisinghe Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL 60501 Jody Randolph Department of Nutrition, University of California Davis, Davis, CA 95616 Mandeep Cheema Department of Nutrition, University of California Davis, Davis, CA 95616 Ravi Tadapaneni Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL 60501 Eunyoung Park Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL 60501 Britt Burton-Freeman Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL 60501 Tissa Kappagoda Department of Internal Medicine, University of California Davis, Davis, CA 95616 DOI: https://doi.org/10.31989/ffhd.v2i12.68 Abstract Objective: Keywords: davis; health; institute
• Agaricus blazei Murill - immunomodulatory properties and health benefits by Biedron, R.; Tangen, J. M.; Maresz, K.; Hetland, G. (2012) - Keywords: Agaricus blazei, AndoSanTM, allergy, asthma, cancer, infection, inflammation, immunomodulation. Agaricus blazei Murill - immunomodulatory properties and health benefits | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 11 (2012): November 2012 / Review Articles Agaricus blazei Murill - immunomodulatory properties and health benefits Authors R. Biedron International Science and Health Foundation, Cracow J. M. Tangen Departmentts of Hematology and 4Cellular Therapy, Oslo University Hospital, Oslo K. Maresz International Science and Health Foundation, Cracow G. Hetland Cellular Therapy, Oslo University Hospital, Oslo DOI: https://doi.org/10.31989/ffhd.v2i11.72 Abstract The Agaricus blazei Murill (AbM), also known as Agaricus brasiliensis L. due to its origin in Brazilian rain forest, is an edible mushroom of the Basidiomycetes family, which also comprises medicinal mushrooms such as Hericium erinaceus and Grifola frondosa. Keywords: health; issn
• Green tea for the prevention of cancer: evidence of field epidemiology by Zhang, Min; Li, Lin; Liu, Ping; Holman, C. D’Arcy J. (2012) - The adjusted HR and 95% CI for case mortality from ovarian cancer was 0.40(0.18-0.90) in the patients who consumed green tea at the highest level compared with non-tea drinkers. Objective: To investigate if green tea consumption was associated with longer survival rates in ovarian cancer patients, and a lower risk of ovarian, breast, and colorectal cancer, in addition to adult leukemia Methods: We have conducted one prospective cohort study in ovarian cancer patients, and five case-control studies in ovarian, breast, and colorectal cancers, and leukemia over the past decade. Keywords: cancer; health; issn; tea
• Health communication to reduce sugar consumption in Thailand by Muangsri, Kanokpong; Tokaew, Wittayatorn; Sridee, Supaporn; Chaiyasit, Kamon (2021) - Keywords: health communication, sugar consumption, sugar, sweetener, sugar tax, social media, non-communicable diseases, NCDs, nutrition label, GDA label, IoT Downloads [Abstract] [Full Article] Published 2021-10-04 Issue Vol. 11 Therefore, health communication to raise awareness and modify the sugar consumption behavior in Thailand focuses on integrative communication in terms of public policies in accordance with the National NCDs Strategic Plan, guidelines and knowledge in sugar consumption including healthy and unhealthy sugar sources, sugar substitutes and their use in functional foods, health problems related to sugar consumption, the use of GDA Nutrition label, and the application of Healthier Choices standards with appropriate sugar content. Keywords: health; sugar
• Voluntary Ingestion of Natural Cocoa Extenuated Hepatic Damage in Rats with Experimentally Induced Chronic Alcoholic Toxicity by Sokpor, Godwin; Addai, Frederick Kwaku; Gyasi, Richard Kwasi; Bugyei, Kwasi Agyei; Ahenkorah, John; Hottor, Bismarck (2012) - The antioxidant and anti-inflammatory properties of polyphenols in NCP are postulated in mitigating the damage of rat liver due to chronic ethanol consumption. No. 5 (2012): May 2012 / Research Articles Voluntary Ingestion of Natural Cocoa Extenuated Hepatic Damage in Rats with Experimentally Induced Chronic Alcoholic Toxicity Authors Godwin Sokpor Department of Anatomy, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra Frederick Kwaku Addai Department of Anatomy, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra Richard Kwasi Gyasi Department of Pathology, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra Kwasi Agyei Bugyei Department of Pharmacology, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra John Ahenkorah Department of Anatomy, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra Bismarck Hottor Department of Anatomy, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra DOI: https://doi.org/10.31989/ffhd.v2i5.91 Abstract Background: Chronic ethanol ingestion causes hepatic damage imputable to an increased oxidative stress engendered by alcoholic toxicity. Keywords: ethanol; health; sciences
• Beneficial effects of gymnemic acid on three-dimensional vascular architecture and expression of vascular endothelial growth factor of intrarenal segmental and interlobar arteries in diabetic rat kidney by Komolkriengkrai, Manaras; Jangchart, Rawipa; Sandech, Nichawadee; Vongvatcharanon, Uraporn; Khimmaktong, Wipapan (2022) - Methods: Rats were divided into five groups including the control group (C), control treated with gymnemic acid (CGM), diabetic animals (DM group) that were rendered diabetic by a single dose [60 mg/kg body weight (BW)] of a streptozotocin (STZ) injection, diabetic rats treated with gymnemic acid (400 mg/kg BW) (GM), and diabetic rats treated with glibenclamide (4 mg/kg BW) (GR). Beneficial effects of gymnemic acid on three-dimensional vascular architecture and expression of vascular endothelial growth factor of intrarenal segmental and interlobar arteries in diabetic rat kidney | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: health; prince; sciences faculty

• Combinations of vitamin A and D are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways by Kanabar, Pinal N.; Los, Nina S.; Lawal, Temitope O.; Patel, Shitalben M.; Raut, Nisikant A.; Maienschein-Cline, Mark; Arbieva, Zarema; Mahady, Gail (2023) - Combinations of vitamin A and D are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 3 (2023): March 2023 / Review Articles Combinations of vitamin A and D are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways Authors Pinal N. Kanabar Nina S. Los Temitope O. Lawal Shitalben M. Patel Nisikant A. Raut Mark Maienschein-Cline Zarema Arbieva Gail Mahady DOI: https://doi.org/10.31989/ffhd.v13i3.1069 Abstract Introduction: Numerous studies over the past 30 years have shown that bioactive compounds present in functional foods, including vitamins, minerals and phytochemicals reduce cancer risk. Keywords: breast; cancer; cells
• Lipid Replacement Therapy: a Functional Food Approach with New Formulations for Reducing Cellular Oxidative Damage, Cancer-Associated Fatigue and the Adverse Effects of Cancer Therapy by Nicolson, Garth L.; Settineri, Robert (2011) - In other diseases, such as chronic fatigue syndrome, fibromyalgia syndrome and other chronic fatiguing illnesses, LRT reduced fatigue by 35.5-43.1% in different clinical trials and increased mitochondrial function. Keywords: nutritional supplements, NT factor®, Coenzyme Q10, cancer fatigue, mitochondria Downloads Keywords: cancer; fatigue
• Molecular basis of the anti-cancer effects of genistein isoflavone in LNCaP prostate cancer cells by Merchant, K.; Kumi-Diaka, J.; Rathinavelu, A.; Esiobu, N.; Zoeller, R.; Hartmann, J.; Johnson, M. (2011) - Molecular basis of the anti-cancer effects of genistein isoflavone in LNCaP prostate cancer cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 Ave Miami Shores FL 33161 J. Kumi-Diaka Department of Biological Sciences, Florida Atlantic University, 3200 College Ave Davie FL 33314 A. Rathinavelu Rumbaugh Goodwin Institute for Cancer Research, Nova Southeastern University, Plantation Fl, 33322 N. Esiobu Department of Biological Sciences, Florida Atlantic University, 3200 College Ave Davie FL 33314 R. Zoeller Department of Health & Exercise Sci, Florida Atlantic University, 3200 College Ave Davie FL 33314 J. Hartmann Department of Biological Sciences, Florida Atlantic University, 3200 College Ave Davie FL 33314 M. Johnson Department of Biological Sciences, Florida Atlantic University, 3200 College Ave Davie FL 33314 DOI: https://doi.org/10.31989/ffhd.v1i3.137 Abstract Background: Prostate cancer is the most common form of non-skin cancer within the United States and the second leading cause of cancer deaths. Keywords: atlantic; cancer; university
• Magnolol Affects Cellular Proliferation, Polyamine Biosynthesis and Catabolism-Linked Protein Expression and Associated Cellular Signaling Pathways in Human Prostate Cancer Cells in vitro by T. McKeown, Brendan; A. R. Hurta, Robert (2015) - Key Words: prostate cancer cells, magnolol, polyamines, MAPK, PI3K, NFκB Downloads Context and purpose of this study: This study investigated the effects of magnolol, a compound found in the roots and bark of the magnolia tree Magnolia officinalis, on cellular proliferation and proliferation-linked activities of PC3 human prostate cancer cells in vitro. Keywords: cancer; prostate; protein
• Precise nutritional modulation of cancer biomarkers through the employment of functional foods and bioactive compounds by McCarthy, Jacqueline; Martirosyan, Danik (2025) - Precise nutritional modulation of cancer biomarkers through the employment of functional foods and bioactive compounds | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 7 (2025): July 2025 / Research Articles Precise nutritional modulation of cancer biomarkers through the employment of functional foods and bioactive compounds Authors Jacqueline McCarthy Danik Martirosyan DOI: https://doi.org/10.31989/ffhd.v15i7.1686 Abstract Cancer remains a leading cause of morbidity and mortality worldwide, prompting growing interest in preventive strategies that target early molecular changes. Keywords: Functional foods, Bioactive Compounds, cancer biomarkers, chemoprevention, epigenetics, metabolomics, personalized nutrition, sulforaphane, bioavailability, dietary intervention, early detection. Keywords: cancer; foods
• Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) Induce Cell Cycle Alterations in DU145 Human Prostate Cancer Cells in Vitro by Affecting the Expression of Cell Cycle-Associated Proteins by Kim, Joseph; McKeown, Brendan; Patel, Kunal; Catalli, Adriana; Kulka, Marianna; Neto, Catherine; Hurta, Robert (2014) - Results: Following treatment of DU145 human prostate cancer cells with 25 µg/mL of PACs for six hours, PACs significantly decreased the cellular viability of DU145 cells. Conclusions: These findings demonstrate that proanthocyanidins from the American cranberry can affect the behaviour of human prostate cancer cells in vitro and further support the potential health benefits associated with cranberries. Keywords: cancer; cells; prostate
• In vivo anti-carcinogenic property of a formulated citrus peel extract by Suzawa, Michiko; Guo, Limin; Pan, Min-Hsiung; Ho, Chi-Tang; Li, Shiming (2014) - Keywords: gold lotion, citrus peel extracts, skin cancer, colon cancer, prostate cancer  Downloads [Abstract] [Full Article] Published 2014-03-31 Issue Vol. 4 No. 3 (2014): March 2014 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Results: The results of these studies demonstrated the efficacy of Gold Lotion (GL), an extract of multiple varieties of citrus peels that contains abundant flavonoids, including a high percentage of polymethoxylflavones (PMFs), which can protect against skin cancer, colon cancer, and prostate cancer in mice. Keywords: cancer; citrus; issn
• Intravenous ascorbic acid protocol for cancer patients: scientific rationale, pharmacology, and clinical experience by Mikirova, N. A.; Casciari, J. J.; Hunninghake, R. E.; Riordan, N. H. (2013) - Intravenous ascorbic acid protocol for cancer patients: scientific rationale, pharmacology, and clinical experience | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 8 (2013): August 2013 / Review Articles Intravenous ascorbic acid protocol for cancer patients: scientific rationale, pharmacology, and clinical experience Authors N. A. Mikirova Riordan Clinic, 3100 N Hillside, Wichita, KS J. J. Casciari Riordan Clinic, 3100 N Hillside, Wichita, KS R. E. Hunninghake Riordan Clinic, 3100 N Hillside, Wichita, KS N. H. Riordan Riordan Clinic, 3100 N Hillside, Wichita, KS DOI: https://doi.org/10.31989/ffhd.v3i8.43 Abstract Background: Ascorbic acid (vitamin C, ascorbate) has been shown to protect cells against various types of oxidant injury at physiologically relevant concentrations. Cancer patients are often deficient in vitamin C, and require large doses to replenish depleted stores. Keywords: cancer; vitamin
• Cancer-specific Therapeutic Potential of Resveratrol: Metabolic Approach against Hallmarks of Cancer by Suh, Dong Hoon; Kim, Mi-Kyung; Kim, Hee Seung; Chung, Hyun Hoon; Song, Yong Sang (2013) - No. 8 (2013): August 2013 / Review Articles Cancer-specific Therapeutic Potential of Resveratrol: Metabolic Approach against Hallmarks of Cancer Authors Dong Hoon Suh Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam Mi-Kyung Kim Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul Hee Seung Kim Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul Hyun Hoon Chung Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul Yong Sang Song Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul DOI: https://doi.org/10.31989/ffhd.v3i8.44 Abstract Cancer hallmarks include evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis. Resveratrol, a polyphenolic phytoalexin, is known to exhibit pleiotropic anti-cancer effects most of which are linked to metabolic reprogramming in cancer cells. Keywords: cancer; seoul
• Interactive effects of 1, 25-dihydroxyvitamin D3 and soy protein extract (SPE) on oral cancer growth in vitro: evidence for potential functional relationships. by Kingsley, Karl; Keiserman, Mark A.; Bergman, Christine J. (2013) - Preliminary work by this group has now demonstrated whole soy protein extract (SPE) inhibits oral cancer cell growth specifically and selectively, through independent cell-cycle and apoptotic pathways. Interactive effects of 1, 25-dihydroxyvitamin D3 and soy protein extract (SPE) on oral cancer growth in vitro: evidence for potential functional relationships. Keywords: cancer; effects; soy
• The influence of obesity in patients with prostate cancer - Review of the literature by Goris Gbenou, Maximilien C. (2013) - Despite, the beneficial role of nutriment in prostate cancer control, the use of functional foods in prostate cancer is not recommended for lack of large epidemiological studies. The influence of obesity in patients with prostate cancer - Review of the literature | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 4 (2013): April 2013 / Review Articles The influence of obesity in patients with prostate cancer - Review of the literature Authors Maximilien C. Goris Gbenou Valence Hospital, Department of Urology, Valence DOI: https://doi.org/10.31989/ffhd.v3i4.63 Abstract Recent studies have demonstrated an association between higher body mass index and increased aggressiveness in prostate cancer. Keywords: cancer; prostate
• Activation of the intrinsic-apoptotic pathway in LNCaP prostate cancer cells by genistein- topotecan combination treatments by Hörmann, Vanessa; Dhandayuthapani, Sivanesan; Kumi-Diaka, James; Rathinavelu, Appu (2013) - Activation of the intrinsic-apoptotic pathway in LNCaP prostate cancer cells by genistein- topotecan combination treatments | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 3 (2013): March 2013 / Research Articles Activation of the intrinsic-apoptotic pathway in LNCaP prostate cancer cells by genistein- topotecan combination treatments Authors Vanessa Hörmann Department of Biological Sciences, Florida Atlantic University, Davie FL 33314 Sivanesan Dhandayuthapani Rumbaugh Goodwin Institute for Cancer Research, Nova Southeastern University, Plantation FL, 33322 James Kumi-Diaka Department of Biological Sciences, Florida Atlantic University, Davie FL 33314 Appu Rathinavelu Rumbaugh Goodwin Institute for Cancer Research, Nova Southeastern University, Plantation FL, 33322 DOI: https://doi.org/10.31989/ffhd.v3i3.64 Abstract Background: Prostate cancer is the second most common cancer in American men. Keywords: cancer; cells; issn
• Anti-cancer activities of Ganoderma lucidum: active ingredients and pathways by Kao, Chi; Jesuthasan, Amalini C.; Bishop, Karen S.; Glucina, Marcus P.; Ferguson, Lynnette R. (2013) - This suggests Ganoderma’s bioactive pathways may compliment that of anti-cancer agents. In this paper we present several potential anti-cancer mechanisms of Ganoderma triterpenes and polysaccharides which can be used for the development of Ganoderma as an anti-cancer agent. Keywords: auckland; cancer
• Functional foods’ bioactive components and their chemoprevention mechanism in cervical, breast, and liver cancers: A systematic review by Teibo, John Oluwafemi; Ayinde, Kehinde Sulaimon; Olaoba, Olamide Tosin; Adelusi, Temitope Isaac; Teibo, Titilade Kehinde Ayandeyi; Bamikunle, Makinde Victor; Jimoh, Yomade Ayodeji; Alghamdi, Saad; Abdulaziz, Osama; Rauf, Abdur; Batiha, Gaber El-Saber (2021) - Keywords: Cervical cancer, Breast cancer, Liver cancer, Cancer prevention, Functional foods, Bioactive compounds Downloads In recent times, emergent studies have provided evidence that functional foods and their bioactive components serve roles as potential agents in the prevention and treatment of cancers. Keywords: breast; cancer; foods
• Anti-Cancer Effect of Angelica Sinensis on Women’s Reproductive Cancer by Zhu, Hong-Hong; Huang, Guo-Hui; Tate, Patricia L.; Larcom, Lyndon L. (2012) - Average viability of MCF-7 was 69.5%, 18.4%, 5.7%, 5.7%, and 5.0% of control for Danggui doses 0.07, 0.14, 0.21, 0.32, and 0.64 ug/ul, respectively, with a Ptrend < 0.0001. Half maximal inhibitory dose (ID50) of Danggui for cancer cell lines MCF-7, CaSki, SiHa and CRL-7368 was 0.10, 0.09, 0.10 and 0.07 ug/ul, respectively. Keywords: cancer; clemson; department
• Combination of vitamins A, D2 and D3 reduce tumor load and alter the expression of miRNAs that regulate genes involved with apoptosis, tumor suppression, and the epithelial-mesenchymal transition in HCT-116 colon cancer cells by Garay Buenrostro, Karen D.; Ostos Mendoza, Keila C.; Kanabar, Pinal N.; Los, Nina S.; Lawal, Temitope O.; Patel, Shitalben M.; López, Alice M.; Cabada-Aguirre, Paulina; Mahady, Gail B.; Maienschein-Cline, Mark; Arbieva, Zarema; Raut, Nishikant A. (2022) - Combination of vitamins A, D2 and D3 reduce tumor load and alter the expression of miRNAs that regulate genes involved with apoptosis, tumor suppression, and the epithelial-mesenchymal transition in HCT-116 colon cancer cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements In Crl:NU(NCr)-Foxn1nu mice injected with HCT-116 colon tumor cells, treatment with vitamin A (25,000 IU) and vitamin D (4,000 IU) or vitamin A (35,000 IU) and vitamin D (5,000 IU) for 21 days significantly reduced tumor growth by ~38% and ~58%, respectively (p < 0.001). Keywords: cancer; cells; hct-116; tumor

• Comparison of Nitrogen Bioaccessibility from Salmon and Whey Protein Hydrolysates using a Human Gastrointestinal Model (TIM-1) by Framroze, Bomi; Savard, Patricia; Gagnon, Diane; Richard, Véronique; Gauthier, Sylvie F (2014) - Keywords: Salmon protein hydrolysate, Whey protein, Nitrogen bioaccessibility, TIM-1 Downloads [Abstract] [Full Article] Published 2014-07-27 Issue Vol. 4 All the products were compared in terms of kinetics of nitrogen absorption through the semipermeable membranes (bioaccessible nitrogen) and nitrogen distribution throughout the intestinal compartments at the end of the 2 hour digestion. Keywords: foods; nitrogen; protein
• Transforming olive pits into functional foods: evaluation of phenolic, antioxidant, nutritional and microbiological properties by Galitsopoulou, Avgoustina; Salepi, Chrisa; Karagianni, Foteini (2022) - Transforming olive pits into functional foods: evaluation of phenolic, antioxidant, nutritional and microbiological properties | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 11 (2022): November 2022 / Research Articles Transforming olive pits into functional foods: evaluation of phenolic, antioxidant, nutritional and microbiological properties Authors Avgoustina Galitsopoulou Dr. Avgoustina Galitsopoulou, Head of Research and Development Department http://orcid.org/0000-0003-2912-9003 Chrisa Salepi Foteini Karagianni DOI: https://doi.org/10.31989/ffhd.v12i10.1011 Abstract Background: The research aims to propose a new potential role for the olive pits as new functional foods for supporting human nutrition, health and wellbeing. The experimental research has been focused on developing a new method to suitably process the by-products of table olives (olive pits) and investigating the health-related and nutritional components of the final products. Keywords: foods; olive; research
• Functional foods in the treatment of type 2 diabetes: olive leaf extract, turmeric and fenugreek, a qualitative review by Boaz, Mona; Leibovitz, Eyal; Dayan, Yosefa Bar; Wainstein, Julio (2011) - Search Search Register Login Home / Archives / Vol. 1 No. 11 (2011): November 2011 / Review Articles Functional foods in the treatment of type 2 diabetes: olive leaf extract, turmeric and fenugreek, a qualitative review Authors Mona Boaz Epidemiology and Research Unit, E. Wolfson Medical Center, Holon, 58100 Eyal Leibovitz Internal Medicine Department A, E. Wolfson Medical Center, Holon, 58100 Yosefa Bar Dayan Diabetes Unit, E. Wolfson Medical Center, Holon, 58100 Julio Wainstein Diabetes Unit, E. Wolfson Medical Center, Holon, 58100 DOI: https://doi.org/10.31989/ffhd.v1i11.114 Abstract Almost 30% of US residents ages 65 and older have diabetes. Many individuals with diabetes make use of functional foods, nutritional supplements, and/or herbal remedies to manage their disease. Keywords: diabetes; foods
• Foods and beverages made from Mexican Purple Corn: a means to increase anthocyanins’ intake by Mendoza-Mendoza, Carmen Gabriela; Soto-Hernánde, Ramón Marcos; Mendoza-Castillo, Ma. del Carmen; Delgado-Alvarado, Adriana; Sánchez-Ramírez, Francisco Javier (2023) - Foods consisted of elote (Mexican street corn or corn on a cob), a snack, and tortillas, while beverages involved what we named functional beverages, infusions, and hot teas. We overlook that the preparation of foods and beverages from these raw materials may represent the development of potential functional foods and a means to increase the dietary intake of AAs.  Keywords: beverages; corn; foods
• Comparative analysis of functional components in Sakekasu (Sake lees) by Nishidono, Yuto; Misaka, Shingen; Maejima, Yuko; Shimomura, Kenju; Tanaka, Ken (2024) - Especially, Figure 2 (f) illustrates the mass chromatograms monitored by the M+ ion of GPC (4, m/z 258.1102), while Table 1 lists the quantitation results of GPC in Sakekasu samples. Concentrations of glycerophosphocholine and S-adenosylmethionine in Sakekasu samples. Keywords: doi; figure; foods; fructose; ion; sakekasu; samples
• Functional foods for weight management: Dietary Fiber – a systematic review by Boaz, Mona; Leibovitz, Eyal; Wainstein, Julio (2013) - However, weight loss management has proven notoriously difficult. Functional foods for weight management: Dietary Fiber – a systematic review | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: foods; weight
• Black tea decreases postprandial blood glucose levels in healthy humans and contains high-molecular-weight polyphenols that inhibit α-glucosidase and α-amylase in vitro: a randomized, double blind, placebo-controlled, crossover trial by Isono, Yoshikazu; Watanabe, Hisako; Kumada, Masafumi; Takara, Tsuyoshi; Iio, Shin-ichiro (2021) - Objective: To investigate the effects of black tea on postprandial blood glucose levels in healthy humans and to identify the components of black tea that inhibit digestive enzymes. Healthy Japanese adults ingested 200 ml of black tea, and its effect on postprandial blood glucose and insulin levels were investigated.  Keywords: foods; tea
• Novel concepts on functional foods and nutrigenomics in healthy aging and chronic diseases: a review of fermented papaya preparation research progress by Marotta, Francesco; Celep, Gulcin Sagdicoglu; Cabeca, Anna; Polimeni, Ascanio (2012) - Novel concepts on functional foods and nutrigenomics in healthy aging and chronic diseases: a review of fermented papaya preparation research progress | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 5 (2012): May 2012 / Review Articles Novel concepts on functional foods and nutrigenomics in healthy aging and chronic diseases: a review of fermented papaya preparation research progress Authors Francesco Marotta ReGenera Research Group for Aging Intervention, Milano, Italy and WHO-Center for Traditional Medicine and Biotechnology, University of Milano Gulcin Sagdicoglu Celep Gazi University, Family and Consumer Sciences Department, Food and Nutrition Technology, Ankara Anna Cabeca Woman’s Health Care Center, Brunswick, GA Ascanio Polimeni ReGenera Research Group for Aging Intervention, Milano, Italy and WHO-Center for Traditional Medicine and Biotechnology, University of Milano DOI: https://doi.org/10.31989/ffhd.v2i5.94 Abstract Functional foods are an emerging research field corresponding with genomical, epidemiological and clinical studies integrated with the food industry in accordance with the consumer demands. Keywords: functional foods, fermented papaya preparation, nutrigenomics Downloads [Abstract] [Full Article] Published 2012-05-19 Issue Vol. 2 Keywords: foods; issn; papaya
• Effect of substituting oats and soybeans on the physicochemical composition of burgers and obtaining functional foods by Hadi, Sara Thamer; Jameel, Firas Riyadh; Hamid, Mohammed Majed (2022) - Effect of substituting oats and soybeans on the physicochemical composition of burgers and obtaining functional foods | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 10 (2022): October 2022 / Research Articles Effect of substituting oats and soybeans on the physicochemical composition of burgers and obtaining functional foods Authors Sara Thamer Hadi Department of Food Sciences/College of Agriculture/University of Anbar/Iraq Firas Riyadh Jameel Mohammed Majed Hamid DOI: https://doi.org/10.31989/ffhd.v12i10.996 Abstract Background: Plant foods, as functional foods, provide not only the essential nutrients needed to sustain life but also low-energy foods for health promotion and disease prevention, the burger, made of several types of meat, contains soy and oats in varying proportions to enhance its chemical and physical properties, as well as to test the efficacy of soy and oat flour as fat alternatives. Objective: The goal of this study was to conduct chemical and physical analyses to Calculation of proportions to determine whether use this type of hamburger Fast food energy reduction might be used for the manufacturing of low- fat beef burgers, the treatment of obesity and autism, Materials and Methods: For both oats and soybeans, there were three burger treatments made of beef, chicken, and lamb, with a ratio of 5, 10, and 15% of each utilized to construct the model items. Keywords: foods; issn

• Potential of multi-strain probiotics extract as an anti-inflammatory agent through inhibition of macrophage migration inhibitory factor activity by Nyotohadi, Denny; Kok, Tjie (2023) - This study aims to evaluate the potential inhibitory effect of the extract of multi-strain probiotics consisting of Lactobacillus casei EMRO 002, L. casei EMRO 213, L. plantarum EMRO 009, L. fermentum EMRO 211, L. rhamnosus EMRO 014, L. bulgaricus EMRO 212,and Rhodopseudomonas palustris EMRO 201 on MIF tautomerase activity, the reversibility, and the mechanism of inhibition. Hence, the scope of this study is the evaluation of the functional characteristics of multi-strain probiotics extract on MIF activity. Keywords: extract; probiotics
• Hypoglycemic and hypolipidemic activity of moringa grown in hydroponics and soil in Ararat Valley by Tadevosyan, Anna; Hakobjanyan, Anahit; Tovmasyan, Anahit; Asatryan, Armenuhi; Roosta, Hamid Reza; Daryadar, Mahsa (2023) - Results: Our results showed that after a 21-day period of stress, the increased level of glucose stays at a high level in control groups, while the use of a hydroponic Moringa extract developed stress tolerance in animals and in soil Moringa extract stabilizes glucose levels in the blood. Materials and Methods: The study was done with the usage of a rabbit model, using water extract of Moringa leaves made with a 150 mg count of leaves on 1 kg weight of the animal. Keywords: extract; glucose; moringa
• The possible anti-inflammatory properties of hydro-ethanolic extract of Oregano by Moghrovyan, Armenuhi; Ginovyan, Mikayel; Avtandilyan, Nikolay; Parseghyan, Lilya; Voskanyan, Armen; Sahakyan, Naira; Darbinyan, Anna (2023) - This study aimed to examine the chemical composition and impact of the Origanum vulgare hydro-ethanolic extract on nociceptive behavior and anti-inflammatory properties in in vivo mice models. Moreover, the Carrageenan test revealed pronounced anti-inflammatory properties of the O. vulgare extract. Keywords: extract; issn
• Phytochemical profile and antioxidant activity of torch ginger (Etlingera elatior) inflorescence extract after in vitro simulated digestion by Mutmainah, Miftah ; Mayangsari, Yunika ; Santoso, Umar ; Chansuwan, Worrapanit ; Sirinupong, Nualpun (2024) - However, investigation on the phytochemical profile and antioxidant activity of torch ginger inflorescence extract following simulated gastrointesinal digestion is still limited. Phytochemical profile and antioxidant activity of torch ginger (Etlingera elatior) inflorescence extract after in vitro simulated digestion | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: activity; extract; inflorescence
• Improving the sensory and chemical characteristics of functional yogurt fortified with cardamom extract (Elettaria cardamomum L.) by Ismael, Firas; Alameri, Zainab ; Kadhim, Ali; Hussein, Ahmed; Mahdi, Saleh; Awda, Jasim; Hadi, Sara (2024) - No. 10 (2024): October 2024 / Research Articles Improving the sensory and chemical characteristics of functional yogurt fortified with cardamom extract (Elettaria cardamomum L.) Authors Firas Najm Ismael Zainab Hadi Abbas Alameri Ali Abdulraheem Kadhim Ahmed Abdulameer Hussein Saleh Abed Al Wahed Mahdi Jasim Mohammed Awda Sara Thamer Hadi DOI: https://doi.org/10.31989/ffhd.v14i10.1454 Abstract Abstract: This study aimed to assess the effects of aqueous cardamom extract on chemical and sensory qualities of yogurt fortified with cardamom extract. Whole milk yogurt was fortified with four different concentrations of aqueous cardamom extract. Keywords: cardamom; extract; yogurt
• Functional evaluation of spirulina extract: antioxidant properties and immune regulation in aged mice models by Liu, Chi-Hsien; Ho, Yi-Chien; Wang, Jing-Ping (2025) - Functional evaluation of spirulina extract: antioxidant properties and immune regulation in aged mice models | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 6 (2025): June 2025 / Research Articles Functional evaluation of spirulina extract: antioxidant properties and immune regulation in aged mice models Authors Chi-Hsien Liu Yi-Chien Ho Jing-Ping Wang DOI: https://doi.org/10.31989/ffhd.v15i6.1634 Abstract Background: Spirulina platensis is a cyanobacterium rich in protein, commonly regarded as a functional food due to its exceptional nutritional profile. Keywords: antioxidant; extract; spirulina
• Effects of Ginger Extract Powder E on attention as a Cognitive Function: A randomized, double-blind, and placebo-controlled parallel study by Nakamura, Naoki; Sano, Yuichi; Suzuki, Naoko; Takara, Tsuyoshi (2025) - Results: At 12 weeks of intervention, the primary outcome—Complex Attention score on the Cognitrax assessment—was significantly higher in the Ginger Extract Powder E group compared with the placebo group, with values exceeding the mean. Conclusions: The results suggest that continuous intake of Ginger Extract Powder E prevents attention decline induced by VDT work and helps maintain concentration. However, there is a lack of research investigating the effects of Ginger Extract Powder E on cognitive function. Keywords: extract; ginger
• Production of citric acid from fermentation solution by cultivation Aspergillus niger-1 strain on an extract obtained from topinambur (Helianthus tuberosus) artichoke tubers by Melkumyan, Inna; Harutyunyan, Baghish; Manukyan, Luiza; Stepanyan, Samvel; Oganezova, Gohar; Avetisyan, Nelly; Melkumyan, Marina (2025) - Production of citric acid from fermentation solution by cultivation Aspergillus niger-1 strain on an extract obtained from topinambur ( Helianthus tuberosus ) artichoke tubers | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Production of citric acid from fermentation solution by cultivation Aspergillus niger-1 strain on an extract obtained from topinambur (Helianthus tuberosus) artichoke tubers Authors Inna E. Melkumyan Baghish A. Harutyunyan Luiza S. Manukyan Samvel Kh. Abstract Background: Citric acid is an organic hydroxycarboxylic tribasic acid. Keywords: acid; extract; tubers
• Novel functional confectionery: incorporating blueberry extract for nutritional enhancement and quality improvement by Dadayan, Slavik; Arstamyan, Lilit; Martirosyan, Danik; Badalyan, Аsya ; Mkhitaryan, Hegine; Abrahamyan, Syuzanna; Khanamiryan, Kristine; Petrosyan, Galust; Grigoryan, Liana; Grigoryan, Valery; Solomonyan, Armen; Dadayan, Ani; Hovhannisyan, Narine (2025) - Literature shows the beneficial role of blueberries and blueberry extract in human consumption, highlighting their importance in promoting a healthy diet. Objective: This research aimed to utilize blueberry extract as a functional ingredient for the development of a novel confectionery product. Keywords: blueberry; extract; issn; products
• Regulation of a synbiotic herbal-probiotic formula (HBF) on alcohol metabolism in human: A randomized controlled trial by Sun, Chenxiang; Li, Feng ; Zhao, Hongyan; Zhang, Pinfeng; Zhang, Yingxin; Jiang, Lulu; Zhao, Tingting; Chen, Lishui; Li, Qiang; Lin, Donglei (2025) - Objectives: This study aims to evaluate the impact of clove bud extract on BSA glycation and elucidate its mechanism of action through molecular simulations. Methods: The antiglycation effects of clove bud extract were evaluated by quantifying glycation-induced changes in BSA structure and aggregation following glucose-mediated glycation and subsequent treatment with varying extract concentrations. Keywords: clove; extract; glycation
• Clove bud extract inhibits glycation of bovine serum albumin: Insights from in vitro and molecular dynamics simulation analysis by Almatroodi, Saleh A Almatroodi (2025) - Objectives: This study aims to evaluate the impact of clove bud extract on BSA glycation and elucidate its mechanism of action through molecular simulations. Methods: The antiglycation effects of clove bud extract were evaluated by quantifying glycation-induced changes in BSA structure and aggregation following glucose-mediated glycation and subsequent treatment with varying extract concentrations. Keywords: clove; extract; glycation
• An extract from date seeds stimulates endogenous insulin secretion in streptozotocin-induced type I diabetic rats by El Fouhil, Ahmed F.; Ahmed, Aly M.; Atteya, Muhammad; Mohamed, Raeesa A.; Moustafa, Amr S.; Darwish, Hasem H. (2013) - A suggestion that date seed extract could stimulate certain cells to differentiate into insulin-secreting cells has been proposed. In order to investigate such a possibility, this study was conducted to measure C-peptide levels in the serum of type 1 diabetic rats treated with date seed extract. Keywords: extract; group; medicine
• Antioxidant and anti-diabetic activities of crude ethanolic extract from the banana inflorescence of musa (ABB group) namwa maliong by Aiemcharoen, Piyapat; Wichienchot, Santad; Sermwittayawong, Decha (2022) - It is well-known to have antioxidants and anti-diabetic potential health benefits.  Keywords: antioxidant activity; banana inflorescence; glucose uptake; anti-diabetic; C2C12 myotubes Downloads Keywords: antioxidant; banana; extract

• Antioxidant potential of gamma ray irradiated winged bean (Psophocarpus tetragonolobus) seed protein hydrolysate by Hlosrichok, Anirut; Aunpad, Ratchaneewan (2023) - Methods:WB seeds were irradiated with gamma ray (WB-G) and total protein were extracted by acid-base extraction method. Keywords:Psophocarpus tetragonolobus; Gamma rays; Protein hydrolysate; Antioxidant activity; Cytoprotective effect Downloads Keywords: gamma; protein
• Bio-active compounds of bitter melon genotypes (Momordica charantia L.) in relation to their physiological functions by Islam, Shahidul; Jalaluddin, Mohammad; Hettiarachchy, Navam S. (2011) - Results: Moisture contents across the four varieties of Bitter Melon flesh ranged between 92.4 and 93.5%, and that of seed ranged between 53.3 and 75.9%. Some amino acids such as Alanine, Glycine, and Valanine were relatively higher in Bitter Melon flesh than in soy protein. Keywords: melon; protein; varieties
• Optimization of Hydrolysis Conditions and Bio-functional Properties of Whey Protein Hydrolysate Obtained from Ash Gourd (Benincasa hispida) Protease by Khadka, Dambar Bahadur; Adhikari , Laxmi ; Khadka, Pragya; Karki, Dhan Bahadur (2024) - AGP hydrolyzed whey protein compared to un-hydrolysed whey protein had significantly higher degree of hydrolysis, DPPH radical scavenging and ACE inhibition activity. Overall, the study showed that the AGP employed whey protein hydrolysate has potential for use as a natural antioxidant and ACE inhibition agent. Keywords: hydrolysis; protein; whey
• Secretion of angiopoietin-like 4 protein from intestinal cells by Nielsen, Soren Drud; Jessen, Randi; Kastrup Dalsgaard, Trine; Young, Jette Feveile (2015) - Possible feedback from ANGPTL4 protein was investigated by adding 0.25 ng/ml recombinant ANGPTL4 protein to culture media. Cells were treated with 9 mM butyrate and the time dependent gene expression and protein secretion to the apical and basolateral side was analysed over a time-course of 24 hours. Keywords: angptl4; protein
• Cost-effectiveness analysis for the treatment of chronic kidney disease with low-protein diet by Mennini, F. S.; Russo, S.; Marcellusi, A.; Palazzo, F.; Quintaliani, P. (2013) - Results: Treatment with a low-protein diet was more effective in terms of QALYs: the difference was always in favour of dietary treatment from a 0.09 QALYS after the first two years, 0.16 after three years, 0.36 after five years and up to a differential of 0.93 year after the first 10 years of treatment. Method: A Markov model was developed to estimate costs and QALYs associated with low protein diet versus no treatment for patients with CKD stage 4-5. Keywords: diet; protein; treatment
• Blood amino acid dynamics after ingestion of chicken-derived peptides in healthy subjects by Guo, Hang; Yamamura, Akihiro; Sato, Mikako (2022) - Keywords: chicken-derived peptides, blood amino acid dynamics, branched-chain amino acid, muscle protein synthesis Downloads {Abstract} {Full Article} Furthermore, it is necessary to consider the timing of protein ingestion, along with its quantity and quality, to regulate the blood AA concentration. Keywords: protein
• Development Sangyod rice protein-based formula for cow milk allergic infant and its gut microbiota modulation by Madtohsoh, Mareeya; Detarun, Preeyabhorn; Wichienchot, Santad (2022) - Materials and methods: The development of infant formula based on Sangyod rice protein and fortified with IMO from Sangyod rice flour was studied on nutrition composition, microbiology, anti-allergenic activity, and effect on gut microbiota. Keywords: Sangyod rice, Infant formula, rice protein-based formula, hypoallergenic formula Downloads {Abstract} {Full Article} Published 2022-07-28 Issue Vol. 12 No. 7 (2022): July 2022 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Keywords: formula; protein; rice
• Amino acid profile of raw and locally processed seeds of Prosopis africana and Ricinus communis: potential antidotes to protein malnutrition by Igwe, Chidi U.; Ojiako, Okey A.; Anugweje, Ken C.; Nwaogu, Linus A.; Ujowundu, Cosmas O. (2012) - Conclusion: P. africana and R. communis seeds are potentially important plant sources of protein and essential amino acids, and so could be of great importance in combating malnutrition and food security problems generally. Threonine was the limiting EAA in raw and fermented P. africana, whereas lysine was the limiting EAA in R. communis raw sample. Keywords: africana; communis; protein

• Effects of sulforaphane glucosinolates from broccoli seed extract on the immune system of healthy Japanese adults by Kouno, Naoyuki; Suzuki, Naoko; Takara, Tsuyoshi (2023) - No. 6 (2023): June 2023 / Research Articles Effects of sulforaphane glucosinolates from broccoli seed extract on the immune system of healthy Japanese adults Authors Naoyuki Kouno Murakami Farm Co., Ltd. Naoko Suzuki ORTHOMEDICO Inc. Tsuyoshi Takara Medical Corporation Seishinkai, Takara Clinic DOI: https://doi.org/10.31989/ffhd.v13i6.1089 Abstract Background: The Purpose of this study was to investigate the effects of sulforaphane glucosinolate (SGS) from broccoli seed extracts on immune function and common cold symptoms in healthy Japanese adults. Conclusion: A period of 8 weeks of SGS intake was shown to alleviate the onset of common cold symptoms in healthy Japanese adults who were prone to catching colds and had a low subjective sense of wellness. Keywords: group; issn; sgs
• The effects of cyclodextran on plaque accumulation in healthy Japanese adults: A randomized, placebo-controlled, double-blind, parallel-group comparison study by Teshima, Hikaru; Kato, Hikaru; Nakamura, Yasuyuki; Suzuki, Naoko; Horiuchi, Masahiko (2024) - The effects of cyclodextran on plaque accumulation in healthy Japanese adults: A randomized, placebo-controlled, double-blind, parallel-group comparison study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 2 (2024): February 2024 / Research Articles The effects of cyclodextran on plaque accumulation in healthy Japanese adults: A randomized, placebo-controlled, double-blind, parallel-group comparison study Authors Hikaru Teshima Hikaru Kato Yasuyuki Nakamura Naoko Suzuki Masahiko Horiuchi DOI: https://doi.org/10.31989/ffhd.v14i2.1324 Abstract Background: Cyclo-isomalto-oligosaccharides (CI) have been reported to inhibit glucosyltransferases (GTF) in vitro. However, there are few clinical studies to investigate the effect of CI on oral plaque via inhibiting GTF activity. Keywords: group; plaque
• Antioxidant Protection against Pathological Mycotoxins Alterations on Proximal Tubules in Rat Kidney by Ali, Awatef; Abdu, Susan (2011) - Animals were gavage administrated and divided into four groups: first group received (sodium bicarbonate), second group received (289 µg OTA /kg B.W. /day), third group received (1mg Ajwa/kg B.W. / day) and fourth group received (289 µg OTA /kg B.W./day+ 1 Results: After 28 days, a significant decrease in body weight, kidney weight and relative weight was detected in OTA treated group. Keywords: group; issn; journal
• Anti-inflammatory, anthropometric and lipomodulatory effects Dyglomera® (aqueous extract of Dichrostachys glomerata) in obese patients with metabolic syndrome by Kuate, Dieudonne; Etoundi, Blanche C.; Ngondi, Judith L.; Muda, Wan; Oben, Julius E. (2013) - The purpose of the present study was to evaluate the effects of Dyglomera®, an aqueous extract of DG (standardized to NLT 10% polyphenols) on certain anthropometric, biochemical (including pro-inflammatory and pro-thrombotic states) and hemodynamic parameters in obese patients with metabolic syndrome. The results confirm the hypothesis that Dyglomera®, the aqueous extract of DG, has anti- inflammatory properties, and is effective in reducing cardiovascular disease risk factors associated with metabolic syndrome in obese human subjects. Keywords: baseline; blood; disease; dyglomera; effects; group; metabolic; obese; placebo; study; syndrome; weight
• Improvement of glucose metabolism and safety of acacia bark-derived proanthocyanidins in healthy Japanese adults: A Randomized, Double-blind, Placebo-controlled, Parallel-group Trial by Baba, Asami; Hoshino, Tomohiro; Ogawa, Sosuke; Takara, Tsuyoshi (2021) - Keywords: Acacia bark extract, Proanthocyanidins, Fasting blood glucose level, HbA1c Downloads [Abstract] [Full Article] Published 2021-09-03 Issue Vol. 11 Herein, we evaluated the effects of acacia bark-derived proanthocyanidins on fasting and postprandial blood glucose levels in healthy Japanese adults with fasting blood glucose (FBG) levels between 110–125 mg/dL. Methods: Subjects were randomly allocated into 2 groups (n = 33 per group) and consumed 6 tablets/day of either tablets of acacia bark extract containing proanthocyanidins (Acacia group) or placebo for 12 weeks. Keywords: acacia; group
• Impact effect of lycopene and tomato-based products network on cardio-protective biomarkers in vivo by El-Nashar, Nermin N.; Abduljawad, Soha Hashim (2012) - Recent studies suggest that the dietary intake of tomatoes and tomato products containing lycopene are associated with a decreased risk of cardiovascular disease. In order to substantiate these facts, the present study was undertaken to investigate the effectiveness of lycopene from tomato products on the potential effects of oxidative stress and atherosclerosis in vivo, focusing on early atherosclerotic events. Keywords: group; issn; tomato
• Anti-obesity effect of eucalyptus leaf extract containing oenothein B in healthy Japanese adults: a randomized, placebo-controlled, double-blind, parallel-group study by Sugimoto, Keiichiro; Fujisawa, Hiroyuki; Nakagawa, Kazuya; Yamamoto, Kazuo; Suzuki, Naoko; Yamashita, Shin-ichiro; Takahashi, Yuta; Kakinuma, Toshihiro; Baba, Asami; Takara, Tsuyoshi; Yamanouchi, Toshikazu (2022) - Baseline 2 323.1 7.8 − − − 　 325.4 8.3 − − − 　 2.3 −20.2 24.8 0.840 4 weeks 3 322.4 8.1 323.5 318.0 329.0 　 321.0 8.2 319.9 314.4 325.5 　 −3.5 −11.4 4.3 0.374 8 weeks 3 322.4 8.3 323.5 318.0 329.0 　 322.1 8.1 321.0 315.4 326.5 　 −2.6 −10.4 5.3 0.521 12 weeks 3 323.8 8.4 324.9 319.4 330.4 　 321.9 8.6 320.7 315.2 326.3 　 −4.2 −12.0 3.6 0.292 ΔTFA (cm 2 ) 4 weeks 3 −0.8 2.8 −0.8 −6.3 4.7 　 −4.4 2.7 −4.3 −9.9 1.2 　 −3.5 −11.4 4.3 0.374 8 weeks 3 −0.7 2.9 −0.8 −6.3 4.7 　 −3.4 2.7 −3.3 −8.9 2.2 　 −2.6 −10.4 5.3 0.521 12 weeks 3 0.6 2.8 0.6 −4.9 6.2 　 −3.6 2.9 −3.6 −9.1 2.0 　 −4.2 −12.0 3.6 0.292 Appendix 4. − − 　 − − 　 −0.1 0.1 −0.1 −0.2 0.1 　 −0.1 0.1 −0.1 −0.3 0.0 　 −0.1 0.1 −0.1 −0.3 0.1 　 −0.2 0.1 −0.2 −0.4 −0.1 　 −0.2 0.1 −0.2 −0.4 0.0 　 −0.5 0.2 −0.5 −0.7 −0.3 Abdominal circumference 4 (cm) 92.1 0.6 　 92.0 0.7 　 91.7 0.6 91.7 90.9 92.5 　 91.6 0.7 91.6 90.8 92.3 　 92.0 0.7 91.9 91.2 92.7 　 91.5 0.7 91.5 90.7 92.3 　 91.4 0.7 91.4 90.6 92.2 　 91.3 0.7 91.3 90.5 92.0 ΔAbdominal circumference 4 (cm) Keywords: group; − −
• Adjuvant benefit of a peptide-rich marine biology formula (LD- 1227) in rheumatoid arthritis: a randomized, double-blind, controlled study by Aldo, Lorenzetti; Umberto, Solimene; Reza, Rastmanesh; Marotta, Francesco; HE, Fang; S, Rasulova; Cristiana, Aperio; Nevenka, Anzulovic; Nicola, Zerbinati (2022) - At 12 weeks, ACR20 beneficial response was 81.0 % in LD-1227 group and 44 % in omega-3 group, (p< 0.01). The superiority of LD-1227 appeared also when considering the ACR50 response at 12 weeks (62% in LD-1227 group as compared to 31 % in omega-3 group, p< 0.01). Keywords: group; issn; journal; ld-1227
• Maltose consumption exacerbates high-fat diet-induced overweight and related parameters in mice by Shibazaki, Nanaka; Tanaka, Wataru; Suzuki, Yusuke; Matsuyama, Hiroki; Kubota, Hibiki; Ogawa, Kenjiro; Yokoyama, Daigo; Sakakibara, Hiroyuki (2022) - Conclusion: The results of this study suggest that daily consumption of maltose exacerbated the development of obesity and related parameters, including body mass index and plasma cholesterol levels, under the high-fat diet consumption. The body mass index rose steadily and was significantly higher in the HFD+Mal group (5.03 ± 0.22), compared to the CD (3.32 ± 0.30) and HFD (4.57 ± 0.40) groups at 12 weeks. Keywords: diet; group; maltose

• Glycophospholipid Formulation with NADH and CoQ10 Significantly Reduces Intractable Fatigue in Western Blot-Positive ‘Chronic Lyme Disease’ Patients: Preliminary Report by Nicolson, Garth L.; Settineri, Robert; Ellithorpe, Rita (2012) - No. 3 (2012): March 2012 / Research Articles Glycophospholipid Formulation with NADH and CoQ10 Significantly Reduces Intractable Fatigue in Western Blot-Positive ‘Chronic Lyme Disease’ Patients: Preliminary Report Authors Garth L. Nicolson Department of Molecular Pathology, The Institute for Molecular Medicine, Huntington Beach, California 92647 Robert Settineri Sierra Research, Irvine, California 92606 Rita Ellithorpe Tustin Longevity Center, Tustin, California 92780 DOI: https://doi.org/10.31989/ffhd.v2i3.100 Abstract Background: An open label 8-week preliminary study was conducted in a small number of patients to determine if a combination oral supplement containing a mixture of phosphoglycolipids, coenzyme Q10 and microencapsulated NADH and other nutrients could affect fatigue levels in long-term, Western blot-positive, multi-symptom ‘chronic Lyme disease’ patients (also called ‘post-treatment Lyme disease’ or ‘post Lyme syndrome’) with intractable fatigue. Methods: The subjects in this study were 6 males (mean age = 45.1 ± 12.4 years) and 10 females (mean age = 54.6 ± 7.4 years) with ‘chronic Lyme disease’ (determined by multiple symptoms and positive Western blot analysis) that had been symptomatic with chronic fatigue for an average of 12.7 ± 6.6 years. Keywords: disease; fatigue; lyme
• Lipid Replacement Therapy Drink Containing a Glycophospholipid Formulation Rapidly and Significantly Reduces Fatigue While Improving Energy and Mental Clarity by Ellithorpe, Rita R.; Settineri, Robert; Mitchell, Cyndee A.; Jacques, Brett; Ellithorpe, Erin; Nicolson, Garth L. (2011) - Recent clinical trials using patients with chronic fatigue have shown the benefit of Lipid Replacement Therapy in restoring mitochondrial electron transport function and reducing moderate to severe chronic fatigue. Keywords: functional food drink, NT Factor®, NT Factor Lipids®, fatigue, mitochondrial function, mental function Downloads [Abstract] [Full Article] Published 2011-08-29 Issue Vol. 1 Keywords: drink; fatigue; tustin
• Effects of seabuckthorn juice consumption on erythropoietin production, fatigue, and quality of life in women: a randomized, placebo-controlled, double-blind, parallel-group study by Jianbiao, Yang; Sofue, Moritsune; Sakamoto, Naomi; Matsumoto, Masako; Duanyang, Wang; Nagata, Maki; Shimizu, Kuniyoshi; Tanaka, Shiori; Nibun, Shigenori; Takeda, Ryuji (2025) - Effects of seabuckthorn juice consumption on erythropoietin production, fatigue, and quality of life in women: a randomized, placebo-controlled, double-blind, parallel-group study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 10 (2025): October 2025 / Research Articles Effects of seabuckthorn juice consumption on erythropoietin production, fatigue, and quality of life in women: a randomized, placebo-controlled, double-blind, parallel-group study Authors Yang Jianbiao Moritsune Sofue Naomi Sakamoto Masako Matsumoto Wang Duanyang Maki Nagata Kuniyoshi Shimizu Shiori Tanaka Shigenori Nibun Ryuji Takeda DOI: https://doi.org/10.31989/ffhd.v15i10.1710 Abstract Background: Seabuckthorn (Hippophae rhamnoides L.) has attracted interest for mitigating transient fatigue, but clinical evidence remains limited. Sixty healthy premenopausal women (20–50 years) with stable menstrual cycles, desk-bound jobs, and transient fatigue with decreased vitality were randomized 1:1 to seabuckthorn juice or a matched control juice. Keywords: fatigue; juice; quality
• Effects of Leu-Asp-Gln-Trp-enriched whey protein hydrolysate on mood and fatigue in healthy adults: A randomized, double-blind, placebo-controlled trial by Nakatsuka, Mayu ; Nabeshima, Kazumi; Sakiyama, Ryo; Sato, Soichiro; Nakano, Manabu; Tanaka, Miyuki; Nakamura, Masahiko (2025) - Conclusions: Daily intake of the WPH enriched with LDQW improved mood state, reduced fatigue, and relieved shoulder discomfort, providing benefits for both mental and physical health. This study evaluated the effects of whey protein hydrolysate (WPH) enriched with the functional tetrapeptide Leu-Asp-Gln-Trp (LDQW) on mood state and fatigue. Keywords: fatigue; mood; placebo
• Effects of Theracurmin® consumption on liver function, fatigue, and sleep: a randomized, double-blind, placebo- controlled, parallel-comparison study by Kuwabara, Yoshitaka; Hirose, Akiko; Lee, Hyunjin; Hashimoto, Daisuke; Iio, Shin-ichiro; Takara, Tsuyoshi (2021) - No. 6 (2021): June 2021 / Research Articles Effects of Theracurmin® consumption on liver function, fatigue, and sleep: a randomized, double-blind, placebo- controlled, parallel-comparison study Authors Yoshitaka Kuwabara Akiko Hirose Hyunjin Lee Daisuke Hashimoto Shin-ichiro Iio Tsuyoshi Takara DOI: https://doi.org/10.31989/ffhd.v11i6.794 Abstract Objective: To evaluate the effects of the eight-week consumption of Theracurmin® on liver function, fatigue, and sleep. Conclusions: These results suggest that the consumption of Theracurmin® or eight weeks improved liver function and fatigue recovery at awakening in healthy Japanese adults. Keywords: fatigue; function; liver
• Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep by Nakano, Masahiko; Yamamoto, Tetsuro; Okamura, Hisayoshi; Tsuda, Akira; Kowatari, Yasuyuki (2012) - The results of the Oguri-Shirakawa-Azumi Sleep Inventory (Middle Aged and Aged version) showed significant improvement in sleepiness at awakening, sleep onset and maintenance, and sleep duration. Furthermore, the changes in these global scores were correlated with changes in the cortisol awakening response (R = -0.55), i.e. the effects of PQQ on improvement of sleep quality are supported by a biomarker. Keywords: fatigue; issn; sleep
• The improvement of daily fatigue in women following the intake of maca (Lepidium meyenii) extract containing benzyl glucosinolate by Honma, Atsushi; Fujiwara, Yumi; Takei, Shin; Kino, Takao (2022) - The improvement of daily fatigue in women following the intake of maca (Lepidium meyenii) extract containing benzyl glucosinolate | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 4 (2022): April 2022 / Research Articles The improvement of daily fatigue in women following the intake of maca (Lepidium meyenii) extract containing benzyl glucosinolate Authors Atsushi Honma Kinos, Inc., 1-3-17 Shinkawa, Chuo-ku, Tokyo, 104-0033, Japan Yumi Fujiwara Department of Kampo Pharmaceutical Science, Nihon Pharmaceutical University, 10281 Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan Shin Takei Kinos, Inc., 1-3-17 Shinkawa, Chuo-ku, Tokyo, 104-0033, Japan Takao Kino Kinos, Inc., 1-3-17 Shinkawa, Chuo-ku, Tokyo, 104-0033, Japan DOI: https://doi.org/10.31989/ffhd.v12i4.912 Abstract Background: Daily fatigue is a problem for many people because of its association with other illnesses. Keywords: maca, Lepidium meyenii, benzyl glucosinolate, daily fatigue, visual analogue scale Downloads [Abstract] [Full Article] Published 2022-04-28 Issue Vol. 12 No. 4 (2022): April 2022 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Keywords: fatigue; maca

• Dialysis Free Protocol for Some End Stage Renal Disease Patients (Khosroshahi Protocol) by Khosroshahi, Hamid Tayebi; Kalantar-zadeh, Kamyar (2012) - Given recent outcome data of the timing of dialysis treatment and the expenses and logistics of hemodialysis procedure have stimulated research on alternative strategies. Conclusion: We conclude that our proposed dialysis free protocol reduces the need for dialysis treatment at least transiently. Keywords: dialysis; disease; protocol
• Neuroprotective and immune effects of active forms of vitamin D3 and docosahexaenoic acid in Alzheimer disease patients by Fiala, Milan; Mizwicki, Mathew T. (2011) - Neuroprotective and immune effects of active forms of vitamin D3 and docosahexaenoic acid in Alzheimer disease patients | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Key words: Alzheimer disease, vitamin D3, DHA, fish oil Downloads Keywords: disease; issn
• Effects of dietary supplementation with fermented papaya on oxidative stress, symptoms, and microbiome in Parkinson's disease by Bolner, Andrea; Bertoldi, Loris; Benvenuto, Giuseppe; Sattin, Eleonora; Bosello, Ottavio; Nordera, Giampietro (2023) - No. 4 (2023): April 2023 / Research Articles Effects of dietary supplementation with fermented papaya on oxidative stress, symptoms, and microbiome in Parkinson's disease Authors Andrea Bolner Loris Bertoldi Giuseppe Benvenuto Eleonora Sattin Ottavio Bosello Giampietro Nordera DOI: https://doi.org/10.31989/ffhd.v13i4.1092 Abstract Background: Oxidative stress, understood as the alteration of the physiological equilibrium between the production of oxygen and nitrogen free radicals and their metabolic neutralization (redox imbalance), is a typical condition of several pathologies, including neurodegenerative ones. Effects of dietary supplementation with fermented papaya on oxidative stress, symptoms, and microbiome in Parkinson's disease | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 Keywords: disease; fpp; issn
• Passiflora ligularis extract improved acetylcholinesterase activity, oxidative stress markers, and neurocognitive outcomes in scopolamine-induced Alzheimer's model in zebrafish by Perez Gutierrez, Rosa Martha; Tellez Gómez, Julio; Hernández Martínez , Diana Maylet ; Muñiz Ramirez, Alethia ; Mota Flores , José María (2025) - Passiflora ligularis extract improved acetylcholinesterase activity, oxidative stress markers, and neurocognitive outcomes in scopolamine-induced Alzheimer's model in zebrafish | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 7 (2025): July 2025 / Research Articles Passiflora ligularis extract improved acetylcholinesterase activity, oxidative stress markers, and neurocognitive outcomes in scopolamine-induced Alzheimer's model in zebrafish Authors Rosa Martha Perez Gutierrez Julio Tellez Gómez Diana Maylet Hernández Martínez Alethia Muñiz Ramirez José María Mota Flores DOI: https://doi.org/10.31989/ffhd.v15i7.1668 Abstract Background: Passiflora ligularis (granadilla) is known for its health benefits, including its potential in managing obesity.  inflammation, and diabetes. PAS treatment significantly improved acetylcholinesterase (AChE) activity, oxidative stress markers, and neurocognitive impairments, demonstrating effects comparable to the donepezil group.  Keywords: disease; issn; ligularis
• Brassicaceae: nutrient analysis and investigation of tolerability in people with Crohn’s disease in a New Zealand study by Campbell, Bobbi; Han, Dug; Triggs, Christopher M.; Fraser, Alan G.; Ferguson, Lynnette R. (2012) - No. 11 (2012): November 2012 / Research Articles Brassicaceae: nutrient analysis and investigation of tolerability in people with Crohn’s disease in a New Zealand study Authors Bobbi Campbell Nutrigenomics New Zealand, Auckland University Dug Han Nutrigenomics New Zealand, Auckland University Christopher M. Triggs Statistics Department, Auckland University Alan G. Fraser Department of Medicine, The University of Auckland Lynnette R. Ferguson Nutrigenomics New Zealand, Auckland University DOI: https://doi.org/10.31989/ffhd.v2i11.70 Abstract Background: Nutrition is an important environmental factor influencing symptoms of Crohn’s disease, one of the two main expressions of inflammatory bowel disease. Brassicaceae: nutrient analysis and investigation of tolerability in people with Crohn’s disease in a New Zealand study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 Keywords: crohn; disease

• Therapeutic Application of Diacylglycerol Oil for Obesity: Serotonin Hypothesis by Yanai, Hidekatsu; Yoshida, Hiroshi; Hirowatari, Yuji; Tada, Norio (2012) - Our study demonstrated that DAG suppresses postprandial increase in TG-rich lipoprotein, very low-density lipoprotein (VLDL), and insulin, as compared with TAG in young, healthy individuals. Our other study demonstrated that DAG suppresses postprandial increase in TG, VLDL-C, and remnant-like particle-cholesterol, in comparison with TAG in an apolipoprotein C-II deficient subject, suggesting that DAG suppresses postprandial TG-rich lipoprotein independently of lipoprotein lipase. Keywords: cells; dag; serotonin
• Nonculturable forms of bacteria in lyophilized probiotic preparations by Blinkova, Larisa; Martirosyan, Danik M; Pakhomov, Yury; Dmitrieva, Olga; Vaughan, Rachel; Altshuler, Michael (2014) - Nonculturable forms of bacteria in lyophilized probiotic preparations | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 4 No. 2 (2014): February 2014 / Research Articles Nonculturable forms of bacteria in lyophilized probiotic preparations Authors Larisa Blinkova FGBU “Mechnikov Research Institute of Vaccines and Sera”, Russian Academy of Medical Sciences, Moscow, 105064 Danik M Martirosyan Functional Food Center Inc., Richardson, TX 75080 Yury Pakhomov FGBU “Mechnikov Research Institute of Vaccines and Sera”, Russian Academy of Medical Sciences, Moscow, 105064 Olga Dmitrieva FGBU “Mechnikov Research Institute of Vaccines and Sera”, Russian Academy of Medical Sciences, Moscow, 105064 Rachel Vaughan Functional Food Center Inc., Richardson, TX 75080 Michael Altshuler FGBU “Mechnikov Research Institute of Vaccines and Sera”, Russian Academy of Medical Sciences, Moscow, 105064 R DOI: https://doi.org/10.31989/ffhd.v4i2.29 Abstract Background: Nonculturable cells are formed under stress. Conclusion: We demonstrated the presence of VBNC cells in lyophilized probiotic preparations that contained live bacteria. Keywords: cells; research; vbnc
• Differential Effects of Tea Extracts on Growth and Cytokine Production by Normal and Leukemic Human Leukocytes by Bayer, Diana; Jansen, Jonathon; Beltz, Lisa A. (2012) - This study compares the effects of different types of tea extracts on viability and cytokine production by normal and leukemic human T lymphocytes. Levels of H2O2 generated by tea extracts were determined using the xylenol-orange method. Keywords: cells; extracts; tea

• Screening and characterization of antioxidant, anti-aging, andanti-microbial activity of herbal extracts by Khonthun, Chakkraphong; Khoothiam, Krissana; Chumphukam, Orada; Thongboontho, Rungthip; Oonlao, Panida; Nuntaboon, Piyawan; Phromnoi, Kanokkarn (2023) - Conclusion: Preliminary studies showed that P. granatum and T. bellirica leaf extracts have antioxidants, anti-aging, and anti-bacterial activitiesand have potential for use as active ingredients for the development of functional foods and cosmetic products. Therefore, the inhibition of these processes can exacerbate anti-aging agents. Keywords: phayao; sciences; university
• The Enhancing Effect of γ-Cyclodextrin Inclusion on γ-Tocotrienol-dependent Negative Growth Control of Mesothelioma Cells in a Xenograft Model by Yano, T.; Sato, A.; Sekine, M.; Kashiwagi, K.; Ota, M. (2011) - In linked with this observation, the level of vascular endothelial growth factor mRNA required for in vivo tumor growth in γ-T3 inclusion with γ-CD group was lower than that in γ-T3 group, on the contrary, the level of γ-T3 level showed an opposite tendency. Findings: Using nude mice bearing MSTO-211H cells (a human malignant mesothelioma cell line), the effect of γ-T3 inclusion with γ-CD on γ-T3 level in tumor tissues, tumor growth, and its related mRNA levels were examined. Keywords: sciences
• Effects of Portabella mushrooms on collagen-induced arthritis, inflammatory cytokines, and body composition in dilute brown non-agouti (DBA1) mice by Peterson, Sandra; Lucas, Edralin A.; Traore, Djibril; Christopher, Lawrance; French, Christine; Clarke, Stephen L.; Lightfoot, Stanley A.; Smith, Brenda J.; Kuvibidila, Solo (2011) - No. 9 (2011): September 2011 / Research Articles Effects of Portabella mushrooms on collagen-induced arthritis, inflammatory cytokines, and body composition in dilute brown non-agouti (DBA1) mice Authors Sandra Peterson Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Edralin A. Lucas Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Djibril Traore Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Lawrance Christopher Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Christine French Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Stephen L. Clarke Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Stanley A. Lightfoot VA Hospital, Oklahoma University Health Sciences Center, Oklahoma City, OK, 73104 Brenda J. Smith Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 Solo Kuvibidila Department of Nutritional Sciences, College of Human Environmental Sciences, Oklahoma State University, Stillwater; OK 74078 DOI: https://doi.org/10.31989/ffhd.v1i9.123 Abstract Background: Exotic mushrooms have long been used in Asia for treatment and/or prevention of chronic diseases due to their immunomodulatory properties. Effects of Portabella mushrooms on collagen-induced arthritis, inflammatory cytokines, and body composition in dilute brown non-agouti (DBA1) mice | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 Keywords: oklahoma state; sciences; state university
• Supplementation of selenium-enriched yeast attenuates age-dependent transcriptional changes of heart in mitochondrial DNA mutator mice by Xiao, Rijin; Spangler, Leya; Routt, Katie; Lan, Zijian; Johnson, Carrie; Prolla, Tomas A; Power, Ronan F (2014) - SP supplementation also caused significant transcriptional changes in the heart, especially in old mice where many age-dependent transcriptional changes were totally or partially reversed by SP. Results: Aging led to significant transcriptional changes, where the expression of 1942 genes in old animals was changed by a fold change larger than 2.0, when compared to young animals. Keywords: alltech; nicholasville; sciences
• Investigation of potential antiviral natural products with an effect on HPV18 E6 protein by molecular docking method by Fazeli, Mehdi; Sarvazad, Hosna; Rahnejat, Nasrin; Rostampour, Rezvan; rad, Mahtab Ghanbari; Eskandari-Roozbahani, Narges (2021) - Results: The docking of HPV18 E6 protein with 19 selected ligands resulted in four compounds, curcumin, silymarin, saikosaponin c, and lactupicrin, showing the best docking scores; they had better binding free energies with HPV E6 protein. No. 11 (2021): November 2021 / Research Articles Investigation of potential antiviral natural products with an effect on HPV18 E6 protein by molecular docking method Authors Mehdi Fazeli Professor of Pharmacology, Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Hosna Sarvazad M.Sc. of Microbiology, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Nasrin Rahnejat M.Sc. of Midwifery Consulting, Kermanshah University of Medical Sciences, Faculty of Nursing and Midwifery, Kermanshah, Iran Rezvan Rostampour M.Sc. of Medical Biochemistry, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Mahtab Ghanbari rad Ph.D. student in Medical Physiology, Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Narges Eskandari-Roozbahani Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran http://orcid.org/0000-0003-2509-9177 DOI: https://doi.org/10.31989/ffhd.v11i11.840 Abstract Background: Infection with the Human Papillomavirus (HPV) causes cellular dysplasia, which leads to cervical cancers in women and penile or rectal cancers in men. Keywords: kermanshah; sciences; university
• Therapeutic efficacy of Genistein-Cytoreg® combination in breast cancer cells by Johnson, M. M.; Kumi-Diaka, K. J.; Zoeller, R.; Graves, B. S.; Merchant, K. T.; Hörmann, V. P.; Hassanhi, M. (2012) - Purpose of the Study: In this study, we investigated the therapeutic efficacy of Cytoreg®-genistein combination on growth inhibition in the MCF-7 human breast cancer cells. Therapeutic efficacy of Genistein-Cytoreg® combination in breast cancer cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: college; davie; sciences

• Evaluation of antioxidant potential, DNA damage and hepatoprotective properties of Lagenaria siceraria plant against acetaminophen induced hepatotoxicity by Singh, Upma; Singh, Pankaj; Singh, Pradeep Kumar; Shukla, Shikha; Singh, Ram Lakhan; Mondal, Sukanta (2023) - Context and purpose of the study: The aim of the present study was to evaluate the phytochemical content, antioxidant activity, DNA damage and hepatoprotective activities of Lagenaria siceraria (LS)plant’s parts to explore their nutraceutical value. Methods: Phytochemical content was measured by the estimation of total phenolics, carotenoids, ascorbic acid, protein and carbohydrates while antioxidant activities were investigated by assaying the parameters of free radical scavenging activity, lipid peroxidation, superoxide anion radical scavenging activity, reducing power, and DNA damage protection assay. Keywords: activity; antioxidant; damage
• Helichrysum arenarium as a source of flavonoids: Evaluation of antimicrobial activity and flavonoid content of extracts of Helichrysum flowers in vitro by Badalyan, Asya; Abrahamyan, Syuzanna; Abovyan, Arevik; Badalyan, Armen; Semerjyan, Gayane; Hovhannisyan, Narine (2024) - Helichrysum arenarium as a source of flavonoids: Evaluation of antimicrobial activity and flavonoid content of extracts of Helichrysum flowers in vitro | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 1 (2024): January 2024 / Research Articles Helichrysum arenarium as a source of flavonoids: Evaluation of antimicrobial activity and flavonoid content of extracts of Helichrysum flowers in vitro Authors Asya Badalyan Syuzanna Abrahamyan Arevik Abovyan Armen Badalyan Gayane Semerjyan Narine Hovhannisyan DOI: https://doi.org/10.31989/ffhd.v14i1.1257 Abstract Background: Helichrysum (family Asteraceae, kind of H. armenium, subfamily of Asteroideae) is known in Armenian traditional medicine for its diuretic, antioxidant, choleretic and anti-inflammatory properties. Keywords: activity; helichrysum
• The study of stabilizing food enzymes using b-cyclodextrins by Karavaeva, Lolita; Kucherenko (Sercova), A.; Rudi, R.; Bulanov, M.; N.V. Glazova, N.V. Glazova; E.I.Kiprushkina, E.I.Kiprushkina (2024) - The study of stabilizing food enzymes using b-cyclodextrins | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 9 (2024): September 2024 / Research Articles The study of stabilizing food enzymes using b-cyclodextrins Authors L.I. Karavaeva A.N.Kucherenko (Sercova) R.V.Rudi M. D.Bulanov N.V. Glazova E.I.Kiprushkina DOI: https://doi.org/10.31989/ffhd.v14i9.1384 Abstract Background: Today, biologically active additives, which contain hydrolytic enzymes (amylase, lipase, protease), are widely used in the digestive industry. Identify the relationship at which the negative influence of external environmental factors is leveled and, as a result, enzymatic activity is maintained for a certain period of time. Keywords: activity; enzymes
• Sedative effects of roasted green tea aroma on autonomic nervous activity, central nervous activity, and subjective mood state in healthy adults by Sugimoto, Akio; Tatsumi, Yuka; Ichitani, Masaki (2025) - Sedative effects of roasted green tea aroma on autonomic nervous activity, central nervous activity, and subjective mood state in healthy adults | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 1 (2025): January 2025 / Research Articles Sedative effects of roasted green tea aroma on autonomic nervous activity, central nervous activity, and subjective mood state in healthy adults Authors Akio Sugimoto Yuka Tatsumi Masaki Ichitani DOI: https://doi.org/10.31989/ffhd.v15i1.1467 Abstract Introduction: To clarify the physiological and psychological effects of roasted green tea aroma, this study examined the effects of roasted green tea extract and its major aromatic components on autonomic nervous activity, central nervous activity, and subjective mood state. The study samples comprised a roasted green tea extract from Shizuoka first-growth green tea (Test I) and three pyrazines, which are the main aromatic components of roasted green tea (Test III). Keywords: activity; tea
• Approaches to studying the increase in the activity and stability of the recombinant aminoacylase from Escherichia coli LGE 36 by Yepremyan, Hasmik (2025) - Novelty: This study uniquely demonstrates the synergistic effect of dithiothreitol (DTT) and cobalt ions (Co+2) in significantly enhancing both the activity and stability of recombinant intracellular aminoacylase from Escherichia coli LGE 36. Keywords: recombinant aminoacylase, Escherichia coli, enzyme, ion metal, reagents, biologically active supplements, functional food industry. Keywords: activity; aminoacylase
• Oleuropein exhibits anticancer effects by inducing apoptosis and inhibiting cell motility in MCF7 and MDA-MB231 breast cancer cells by Haffani, Yosr; Torkhani, Montassar; Ben Halim , Nizar ; Chrigui, Souhaieb ; Ben Mami, Naira; Boudhrioua, Nourhene ; Safra, Ines; Darmoul, Dalila (2025) - Novelty: This study uniquely demonstrates the synergistic effect of dithiothreitol (DTT) and cobalt ions (Co+2) in significantly enhancing both the activity and stability of recombinant intracellular aminoacylase from Escherichia coli LGE 36. Keywords: recombinant aminoacylase, Escherichia coli, enzyme, ion metal, reagents, biologically active supplements, functional food industry. Keywords: activity; aminoacylase

• Effect of sorghum intake on postprandial blood glucose levels: A randomized, double-blind, crossover study by Miyazaki, Hitomi; Nagae, Masumi; Uchida, Hiroshi; Shimizu, Kuniyoshi (2024) - Effect of sorghum intake on postprandial blood glucose levels: A randomized, double-blind, crossover study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 1 (2024): January 2024 / Research Articles Effect of sorghum intake on postprandial blood glucose levels: A randomized, double-blind, crossover study Authors Hitomi Miyazaki Kyushu University Masumi Nagae Kyushu University Hiroshi Uchida BEST AMENITY Co.,Ltd. Keywords: blood; glucose
• Polysaccharides from split gill mushrooms (Schizophyllum commune Fr.) improve glucose metabolism and reduce muscleinflammation in a rat model of type 2 diabetes by Khimmaktong, Wipapan; Matsathit, Udomlak; Nuinamwong, Supada; Sermwittayawong, Decha; Chubuathong, Patranis ; Sukpondma, Yaowapa; Radenahmad, Nisaudah; Komolkriengkrai, Manaras (2025) - Treatment with S. commune polysaccharides significantly lowered blood glucose levels, reduced inflammatory markers, and restored the expression of GLUT4 and GLP-1R, with results comparable to metformin-treated rats. Methods: Male Wistar rats were divided into five groups: normal diet (ND), ND with 240 mg/kg body weight (BW) S. commune polysaccharides (ND240), high-fat diet-induced diabetic rats (HFD+DM), HFD+DM treated with S. commune polysaccharides (HFD+S240), and HFD+DM treated with metformin (HFD+Met). Keywords: commune; glucose; polysaccharides
• Suppressive effect of a single dose of monoglucosyl rutin on postprandial blood glucose elevation: A randomized, placebo-controlled, double-blind crossover study by Hashizume, Yushi; Tandia, Mahamadou (2021) - Foundation: Toyo Sugar Refining Co., Ltd. Keywords: monoglucosyl rutin, blood glucose level, incremental area under the curve, α-amylase, α-glucosidase, crossover study Downloads Conclusions: We suggest that MR has a suppressive effect on the elevation of postprandial blood glucose in healthy adults with relatively high fasting blood glucose levels. Keywords: blood; glucose; issn
• Hypoglycemic effects of antioxidant-rich plant extracts on postprandial glycemic responses in participants with prediabetes (GLARE study) by Lim, Wen Xin Janice; Gammon, Cheryl S.; von Hurst, Pamela R.; Chepulis, Lynne; Mugridge, Owen; Page, Rachel A. (2021) - Hypoglycemic effects of antioxidant-rich plant extracts on postprandial glycemic responses in participants with prediabetes (GLARE study) | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 No. 11 (2021): November 2021 / Research Articles Hypoglycemic effects of antioxidant-rich plant extracts on postprandial glycemic responses in participants with prediabetes (GLARE study) Authors Wen Xin Janice Lim Massey University https://orcid.org/0000-0002-0222-6324 Cheryl S. Gammon Massey University Pamela R. von Hurst Massey University Lynne Chepulis Waikato Medical Research Centre, University of Waikato Owen Mugridge Massey University Rachel A. Page Massey University DOI: https://doi.org/10.31989/ffhd.v11i11.829 Abstract Background: Plant extracts may help to improve glycemic control in individuals with poor glycemic control. Trial Registration ID: ACTRN12617000837325 Keywords: grape seed extract; rooibos tea extract; olive leaf extract; impaired glycemic control; hyperglycemia; hypoglycemic effects; insulin sensitivity; beta-cell function Downloads Keywords: extracts; glucose; insulin
• Effect of Raphanus sativus on Glucose, Cholesterol and Triglycerides Levels in Glucose Loaded Rats by Elnour, Rehab Omer; EzzEldin, Omar Musa; Mariod, Abdalbasit Adam; Ahmed, Reem Hassan; Eltahir, Ahlam Salih (2022) - No significant difference was seen in triglyceride level after 2 weeks of administration of Radish extract compared with start point. Effect of Raphanus sativus on Glucose, Cholesterol and Triglycerides Levels in Glucose Loaded Rats | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 3 (2022): March 2022 / Research Articles Effect of Raphanus sativus on Glucose, Cholesterol and Triglycerides Levels in Glucose Loaded Rats Authors Rehab Omer Elnour Omar Musa EzzEldin Abdalbasit Adam Mariod Reem Hassan Ahmed Ahlam Salih Eltahir DOI: https://doi.org/10.31989/ffhd.v12i3.883 Abstract Background: In fact, diabetes is now a serious health concern, and the import of medications from other countries consumes a significant amount of foreign cash each year. Keywords: glucose; radish; raphanus
• Suppression of blood glucose level elevation and promotion of GLP-1 secretion by ingestion of Undaria pinnatifida sporophylls (Mekabu): Open-label crossover design by Takano, Shiori; Yoshizumi, Kazuma; Kobayashi, Hitomi; Iwamoto, Naoki; Taga, Masaki (2022) - Suppression of blood glucose level elevation and promotion of GLP-1 secretion by ingestion of Undaria pinnatifida sporophylls (Mekabu): Open-label crossover design | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 2 (2022): February 2022 / Research Articles Suppression of blood glucose level elevation and promotion of GLP-1 secretion by ingestion of Undaria pinnatifida sporophylls (Mekabu): Open-label crossover design Authors Shiori Takano Faculty of Human Ecology, Wayo Women’s University Kazuma Yoshizumi Kaneryo Sea Vegetable Corporation Hitomi Kobayashi Faculty of Human Nutrition, Seitoku University Naoki Iwamoto Faculty of Contemporary Human Life Science, Tokyo Kasei Gakuin University Masaki Taga Faculty of Human Ecology, Wayo Women’s University DOI: https://doi.org/10.31989/ffhd.v12i2.891 Abstract Background: It has been confirmed that the daily consumption of seaweed such as Wakame (Undaria pinnatifida) and Kombu (Saccharina japonica) has an inhibitory effect on the rise in postprandial blood glucose levels. In this study, we examined the effects of preprandial intake of Mekabu on postprandial blood glucose levels and blood glucose regulation-related hormones in healthy young women. Keywords: blood; glucose; mekabu

• Dynamics of bioactive substances accumulation during cauliflower maturation as a way to ensure functional crop properties by Tadevosyan, Laura; Martirosyan, Gayane; Tsereteli, Irina; Vardanyan, Irina; Zadayan, Meruzhan; Avagyan, Alvina (2023) - Ascorbic acid content in cauliflower heads was determined by the titration method. Objective: To determine the dependence of the content of bioactive components (ascorbic acid, B vitamins, macronutrients) on the stage of maturity of cauliflower heads and on the growing period. Keywords: acid; cauliflower
• New generation of functional yogurts fermented with probiotic lactic acid bacteria isolated from human milk by Danielyan, Lusine; Hovhannisyan, Hrachya; Baghdasaryan, Lusine; Barseghyan, Andranik (2024) - New generation of functional yogurts fermented with probiotic lactic acid bacteria isolated from human milk | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 4 (2024): April 2024 / Research Articles New generation of functional yogurts fermented with probiotic lactic acid bacteria isolated from human milk Authors Lusine Danielyan Hrachya Hovhannisyan Lusine Baghdasaryan Andranik Barseghyan DOI: https://doi.org/10.31989/ffhd.v14i4.1347 Abstract Background: The cultures used in the production of bio-yoghurts typically consist of a blend of traditional yogurt starters, such as S. thermophilus and L. delbrueckii subsp. Objective: This research aims to develop a new generation of sustainable functional yoghurts suitable for consumers of all ages using as starters predominant probiotic lactic acid bacteria isolated from the breast milk of healthy women. Keywords: acid; milk
• Changes of volatile flavored compounds during lactic acid fermentation in cereal-based products by Sah, Sagnik; Putatunda, Shyarshree; Majumder, Rajib; Das, Arpita (2024) - Keywords: Cereal-based food, Volatile flavor compounds, Lactic acid bacteria, Fermentation, Amino acid metabolism, HPLC, GC-MS Downloads Changes of volatile flavored compounds during lactic acid fermentation in cereal-based products | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 11 (2024): November 2024 / Review Articles Changes of volatile flavored compounds during lactic acid fermentation in cereal-based products Authors Sagnik Sah Shyarshree Putatunda Rajib Majumder Arpita Das DOI: https://doi.org/10.31989/ffhd.v14i11.1503 Abstract Lactic acid bacteria (LAB)-mediated fermentation of cereals is a preservation technique that enhances food flavor, nutrition, and safety. Keywords: acid; fermentation
• Seaberry ursolic acid improves daytime frequency and urgency of urination in healthy Japanese subjects: A randomized, placebo-controlled, double-blind trial by Shimizu, Norihito; Shimizu, Ryoma; Yagihashi, Masahiro; Goto, Kazunori; Shimoda, Hiroshi; Hirano, Marina; Shimizu, Hiroyuki ; Yamada, Shizuo (2025) - Conclusions: The intake of ursolic acid (0.2 mg/day) reduced daytime urination frequency and urgency. Daytime urination frequency significantly decreased after 3 weeks of ursolic acid supplementation, and a significant correlation between the number of daytime urinations and time was detected in the ursolic acid group. Keywords: acid; subjects; urination
• Maternal diet, LCPUFA status and prematurity in Indian mothers: A cross-sectional study by Ranade, Prachi S.; Rao, Shobha S. (2012) - Results: The frequency of intake of n-3 fatty acid rich varieties of fish was higher (p<0.05) in FT mothers compared to PT mothers. Among age, parity, and neonatal sex matched case-control pairs, PT mothers had significantly (p<0.01) higher levels of n-6 ARA, but lower (p<0.01) levels of n-3 DHA and total n-3 fatty acids compared to FT mothers irrespective of socioeconomic group. Keywords: acid; issn; mothers
• Effects of luteolin-rich chrysanthemum flower extract on purine base absorption and blood uric acid in Japanese subjects by Takara, Tsuyoshi; Yamamoto, Kazuo; Suzuki, Naoko; Yamashita, Shin-ichiro; Iio, Shin-ichiro; Kakinuma, Toshihiro; Baba, Asami; Takeda, Shogo; Yamada, Wakana; Nagata, Masafumi; Shimoda, Hiroshi (2022) - Serum uric acid levels after 12 weeks were assessed as the primary outcome, and uric acid were measured before and after 4 weeks of the intervention as secondary outcomes. We previously demonstrated that the ingestion of Chrysanthemum flower extract (CFE) for 1 month reduced serum uric acid levels. Keywords: acid; cfe; serum

• Blood homocysteine and fasting insulin levels are reduced and erythrocyte sedimentation rates increased with a glycophospholipid-vitamin formulation: a retrospective study in older subjects by Ellithorpe, Rita R.; Settineri, Robert; Ellithorpe, Talon; Nicolson, Garth L. (2015) - Conclusions: The test formulation was an effective method to reduce Hcys and fasting insulin blood levels and increase ESR rates in older subjects without adverse effects. Differences were also found in fasting insulin levels (from 12.80±3.11 to 5.30±1.77 µIU/mL, 58.6% reduction, t-test, p<0.005) and erythrocyte sedimentation rate (ESR). Keywords: blood; study; test
• Effect of 1-O-Alcylglycerols from sea hydrobionts on the metabolic status of rats with alimentary dyslipidemia by Karaman, Yulia K.; Novgorodtseva, Tatyana P.; Gvozdenko, Tatyana A.; Kasynov, Sergey P. (2013) - The content of initial and final products of lipid peroxidation – hydroperoxides of lipids (HPL), malondialdehydes (MDA) in the blood were investigated. These data suggest the widespread use of AG from lipid liver squid Berryteuthis magister in rehabilitation practice of various pathologies. Keywords: blood; rats; vladivostok
• Effects of the consumption of proanthocyanidins derived from acacia bark on blood pressure in healthy Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparison study by Baba, Asami; Hoshino, Tomohiro; Ogawa, Sosuke; Takara, Tsuyoshi (2021) - Furthermore, “the ratio of the number of subjects whose sitting systolic blood pressure <130 mmHg and diastolic blood pressure ≤89 mmHg at 12 weeks” of the Acacia group was significantly higher than that of the placebo group.  The primary outcome was the measured value of sitting systolic blood pressure at 12 weeks, whereas the secondary outcomes were sitting systolic and diastolic blood pressures, superoxide dismutase activity in blood, and blood flow. Keywords: acacia; blood

• Comparative analysis of the effect of fermented derivatives from Bactrian milk on the gut microbiome by Samat, Kozhakhmetov; Tamara, Tultabayeva; Maxat, Suieubayev; Nurislam, Muhanbetganov; Zhanel, Pernebek; Dinar, Tarzhanova; Indira, Uyzbayeva; Zhanagul, Khassenbekova; Akmaral, Zhantureyeva; Zharkyn, Jarmukhanov; Saniya, Kozhakhmetova; Almagul, Kushugulova (2023) - Results:After 4 weeks of intervention, the relative abundance of bacterial taxa varied significantly in the BCM and Bactrian milk derivative groups. Keywords: Bactrian camel milk, gut microbiota, rats, yogurt, soft cheese Author Biography Kozhakhmetov Samat, National Laboratory Astana, Nazarbayev University, Astana, Z05H0P9, Kazakhstan Leading Researcher of Microbiome Laboratory Downloads Keywords: gut; issn; milk
• Improvement of functional and sensory properties of fermented dairy drink Narine using raw apricot gum by Hovhannisyan, Hrachya G.; Danielyan, Lusine ; Chichoyan, Naira; Pashayan, Maria; Baghdasaryan, Lusine; Melkumyan, Inna; Barseghyan, Andranik (2024) - Subsequently, the samples were inoculated with L. helveticus culture at a concentration of 5% and incubated at 37°C. The stimulation of L. helveticus growth leads to a significant increase in the rate of coagulation and acidification of milk, improving the consistency and viscosity of Narine. Keywords: apricot; milk; properties
• Bioactive proteins against pathogenic and spoilage bacteria by Sitohy, Mahmoud Z; Osman, Ali O; Mahgoub, Samir A (2014) - It is concluded that supplementation with MSP (0.5%) can prolong the shelf life of pasteurized milk from 6 to 16 days when stored under cold conditions and from 8 to 18 h when stored at room temperature based on milk total bacterial count, acidity, and pH measurements- as well as the intact status of milk proteins visualized by SDS electrophoresis Previous reports indicated that basic proteins or peptides can have antimicrobial activity [9]. Keywords: action; bacteria; cell; glycinin; milk; proteins
• Effects of kefir consumption on carbohydrate profile of mother’s milk by Kurt, Tuğçe Tok; Gökırmaklı, Çağlar; Guzel-Seydim, Zeynep B (2021) - No. 9 (2021): September 2021 / Research Articles Effects of kefir consumption on carbohydrate profile of mother’s milk Authors Tuğçe Tok Kurt Suleyman Demirel University, Department of Food Engineering Isparta 32260 Turkey Çağlar Gökırmaklı Suleyman Demirel University, Department of Food Engineering Isparta 32260 Turkey Zeynep B Guzel-Seydim Suleyman Demirel University, Department of Food Engineering Isparta 32260 Turkey DOI: https://doi.org/10.31989/ffhd.v11i9.819 Abstract Background: Human milk contains the nutrients necessary for the growth and development of babies as it contains essential bioactive components to support the immune system. Effects of kefir consumption on carbohydrate profile of mother’s milk | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Keywords: milk; mother

• The Effects of Intravenous Vitamin C Administration on hs-CRP and Tumor Necrosis Factor-α Levels in Haemodialysis Patients by Khosroshahi, Hamid Taiebi; Talebi, Yashar; Ahmadzadeh, Siamak; Habibzadeh, Afshin; Mousavi, Seyyed Ehsan; Khalilzadeh, Mohammadreza (2011) - Objectives: The aim of this study is to determine the changes of hs-CRP and Tumor Necrosis Factor-α (TNF-α) levels after administration of vitamin C in End Stage Renal Disease patients (ESRD) on Hemodialysis Methods and Materials: Besides hs-CRP and TNF-α, detailed laboratory results were evaluated before and after the study. Keywords: crp; vitamin
• Vitamin A and D3 combinations reduce breast cancer tumor load in a postmenopausal MCF-7 xenograft mouse model in a dose- and time- dependent manner by Raut, Nishikant; Lawal, Temitope; Adeniyi, Bolanle; Kanabar, Pinal; Maienschein-Cline, Mark; Los, Nina; Arbieva, Zarema; Mahady, Gail (2024) - Methods: MCF-7 breast cancer cells were grown in culture for the xenograft experiments. Transcriptomic analysis of treated MCF-7 cells also showed that the combination significantly upregulated the apoptosis and unfolded protein response canonical pathways, and reduced estrogen signaling. Keywords: mcf-7; tumor; vitamin
• Vitamin C: optimal dosages, supplementation and use in disease prevention by Pacier, Callen; M. Martirosyan, Danik (2015) - Vitamin C: optimal dosages, supplementation and use in disease prevention | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 3 (2015): March 2015 / Review Articles Vitamin C: optimal dosages, supplementation and use in disease prevention Authors Callen Pacier Functional Food Center/Functional Food Institute, Dallas, TX 75252, USA Danik M. Martirosyan Functional Food Center/Functional Food Institute, Dallas, TX 75252, USA DOI: https://doi.org/10.31989/ffhd.v5i3.174 Abstract Background: The importance of vitamin C as a way to prevent scurvy has been known for centuries. This review of scientific literature will evaluate many aspects of vitamin C including deficient versus optimal blood plasma levels, adequate daily amounts necessary to maintain ideal levels, and the safety of higher doses. Keywords: vitamin
• Superiority of the body roundness index over BMI in linking central adiposity with vitamin D3: A cross-sectional study in Iraqi adults by Kadhim, Sura; Al-Atta, Duaa ; Samarraee, Monaf (2025) - The Body Roundness Index may be a better measure, although data for Middle Eastern adults are limited.  Objectives: To investigate the association of animal-fat consumption with adiposity indices as well as vitamin D3, and compare BRI with BMI as a marker of body fat in Iraqi adults.  Superiority of the body roundness index over BMI in linking central adiposity with vitamin D3: A cross-sectional study in Iraqi adults | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 11 (2025): November 2025 / Research Articles Superiority of the body roundness index over BMI in linking central adiposity with vitamin D3: A cross-sectional study in Iraqi adults Authors Sura Talal Kadhim Duaa Mohammed Al-Atta Monaf Faik Ahmeed Al Samarraee DOI: https://doi.org/10.31989/ffhd.v15i11.1798 Abstract Background: Body mass index is a poor measure of central adiposity. Keywords: adiposity; vitamin
• Serum levels of vitamin D, calcium, phosphorus, and oxidative parameters in healthy and diabetic people by Barghi, Maryam; Sadeghipoor Ranjbar, Amir; Moazen, Homa; Eskandari-Roozbahani, Narges (2021) - According to our results, the mean of vitamin D in T2DM was significantly lower than healthy people and MDA in T2DM significantly increased compared to the control group, suggesting that increasing the activity of this enzyme in the development of secondary complications in diabetic patients is a predisposing factor. Serum levels of vitamin D, calcium, phosphorus, and oxidative parameters in healthy and diabetic people | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Keywords: issn; vitamin
• The effect of vitamin D deficiency state on oxidized low-density lipoprotein alteration in patients with type 2 diabetes by Salehi, Salome Sadat; Karimpour, Sahar; Rabizadeh, Soghra; Esteghamati, Alireza; Rajab, Armin; Salehi, Sousan Sadat; Nakhjavani, Manouchehr; Mirmiranpour, Hossein (2021) - ROC curve analysis of FBS, PPG, HbA1C, and oxLDL showed these markers are independent predictors of severe vitamin D deficiency and significantly discriminate between very low and low levels of vitamin D deficiency in patients with diabetes.  Results: Patients with severe vitamin D deficiency had higher FBS, PPG, HbA1C, and oxLDL than the vitamin D deficient group (P<0.05). Keywords: deficiency; vitamin

• Nutrigenomics of Neuradaptogen Amino-Acid-Therapy and Neurometabolic Optimizers: Overcoming carbohydrate bingeing and overeating through neurometabolic mechanisms by Blum, Kenneth; Bagchi, Debasis; Bowirrat, Abdalla; Downs, B. William; Waite, Roger L.; Giordano, John; Morse, Siohban; Madigan, Margaret; Downs, Jaclyn M.; Braverman, Eric R.; Polanin, Margaret; Barh, Debmayla; Fornari, Frank; Simpatico, Thomas (2011) - No. 9 (2011): September 2011 / Review Articles Nutrigenomics of Neuradaptogen Amino-Acid-Therapy and Neurometabolic Optimizers: Overcoming carbohydrate bingeing and overeating through neurometabolic mechanisms Authors Kenneth Blum Department of Psychiatry, University of Florida, College of Medicine, Mcknight Brain Institute, Gainesville, Florida Debasis Bagchi Innovative Research and Clinical Trials, Iovate Inc., Toronto Abdalla Bowirrat Clinical Neuroscience and Population Genetics, Ziv Government Medical Center B. William Downs Department of Personalized Medicine, Reward Deficiency Solutions, LLC, San Diego, California Roger L. Waite Department of Personalized Medicine, Reward Deficiency Solutions, LLC, San Diego, California John Giordano Deaprtment of Holistic Medicine, G and G Hoistic Addiction Treatment Center, North Miami Beach Siohban Morse Deaprtment of Holistic Medicine, G and G Hoistic Addiction Treatment Center, North Miami Beach Margaret Madigan Department of Personalized Medicine, Reward Deficiency Solutions, LLC, San Diego, California Jaclyn M. Downs Department of Personalized Medicine, Reward Deficiency Solutions, LLC, San Diego, California Eric R. Braverman Department of Clinical Neurology, Path Foundation NY, New York, New York Margaret Polanin Department of Neurological Surgery, Weill Cornell College of Medicine, New York, New York Debmayla Barh Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology (IIOAB), Nonakuri, Purba Medinipur, West Bengal 721172 Frank Fornari Dominion Diagnostics Inc. This review will provide significant evidence to substantiate the existence of Reward Deficiency Syndrome in Obesity and the role of catecholaminergic pathways in aberrant substance seeking behavior, in particular cravings for carbohydrates. Keywords: deficiency; department; medicine; reward
• Inhibition of SIRT1 Transcription in Resveratrol-differentiated Medulloblastoma Cells by Ma, Jing-Xin; Li, Hong; Cheng, Xiao-Xin; Wu, Mo-Li; Yu, Li-Jun; Kong, Qing-You; Liu, Ming; Liu, Jia (2013) - Objective: The present study aimed to address the expression patterna of SIRT1 in medulloblastoma tissues and non-cancerous counterparts and to explore whether resveratrol exerts its anti-medulloblastoma effects via regulating SIRT1 expression and bioactivity. To clarify the function of SIRT1 in medulloblastomas, SIRT1 expression in UW228-3 medulloblastoma cells were suppressed by RNA interference (RNAi). Keywords: biology; dalian; department
• Bioactive form of resveratrol in glioblastoma cells and its safety for normal brain cells by Shu, Xiao-Hong; Li, Hong; Sun, Xiao-Xin; Sun, Zheng; Wang, Li-Li; Song, Xue; Shi, Shun; Wu, Mo-Li; Chen, Xiao-Yan; Kong, Qing-You; Jia, Liu (2013) - Bioactive form of resveratrol in glioblastoma cells and its safety for normal brain cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 5 (2013): May 2013 / Research Articles Bioactive form of resveratrol in glioblastoma cells and its safety for normal brain cells Authors Xiao-Hong Shu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Hong Li Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Xiao-Xin Sun Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Zheng Sun Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Li-Li Wang Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Xue Song Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Shun Shi Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Mo-Li Wu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Xiao-Yan Chen Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Qing-You Kong Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 Liu Jia Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, Dalian Medical University, Dalian 116044 DOI: https://doi.org/10.31989/ffhd.v3i5.57 Abstract Background: Resveratrol, a plant polyphenol existing in grapes and many other natural foods, possesses a wide range of biological activities including cancer prevention. The findings from PBCs suggest that an effective anti-glioblastoma dose of resveratrol may not exert side-effect on normal brain cells, providing a strong evidence for practical use of resveratrol in the management of human brain malignancies. Keywords: cell biology; dalian; department
• Hepatoprotective and anti-inflammatory profile of sokeikakketsuto and makyoyokukanto in primary cultured rat hepatocytes by Sakaguchi, Tatsuma; Okuyama, Tetsuya; Kotsuka, Masaya; Yoshida, Terufumi; Okumura, Tadayoshi; Nishizawa, Mikio; Kaibori, Masaki; Sekimoto, Mitsugu (2022) - Search Search Register Login Home / Archives / Vol. 12 No. 2 (2022): February 2022 / Research Articles Hepatoprotective and anti-inflammatory profile of sokeikakketsuto and makyoyokukanto in primary cultured rat hepatocytes Authors Tatsuma Sakaguchi Kansai Medical University, Department of Surgery Tetsuya Okuyama Kansai Medical University, Department of Surgery Masaya Kotsuka Kansai Medical University, Department of Surgery Terufumi Yoshida Kansai Medical University, Department of Surgery Tadayoshi Okumura Kansai Medical University, Department of Surgery, Research Organization of Science and Technology, Ritsumeikan University Mikio Nishizawa Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Japan Masaki Kaibori Kansai Medical University, Department of Surgery Mitsugu Sekimoto Kansai Medical University, Department of Surgery DOI: https://doi.org/10.31989/ffhd.v12i2.887 Abstract Background: Hepatoprotective and anti-inflammatory profile of sokeikakketsuto and makyoyokukanto in primary cultured rat hepatocytes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: department; medical; university

• Gut Microbiome modulation in patients treated with an enriched nutraceutical composition: a multi target strategy by Natale, Francesco; Fusco, Chiara; Limatola, Mirella; Cante, Luigi; Alfieri, Roberta; Mollo, Noemi; Franzese, Rosa; D'Elia, Saverio; Cimmino, Giovanni (2024) - Search Search Register Login Home / Archives / Vol. 14 No. 12 (2024): December 2024 / Research Articles Gut Microbiome modulation in patients treated with an enriched nutraceutical composition: a multi target strategy Authors Francesco Natale Chiara Fusco Mirella Limatola Luigi Cante Roberta Alfieri Noemi Mollo Rosa Franzese Saverio D'Elia Giovanni Cimmino DOI: https://doi.org/10.31989/ffhd.v14i12.1437 Abstract Introduction: The contribution of gut microbiota to health and disease is now well accepted and under continuous investigation. However, if these effects are attributed to gut microbiota remain unknown. Keywords: gut; issn; microbiota
• Microalgae and the gut microbiome: Insights from animal models to human trials by Paterson, Samuel; Olasehinde, Tosin; Gómez-Cortés, Pilar ; Hernández-Ledesma, Blanca (2025) - Microalgal-rich diets have shown promise by modulating fatty acid metabolism, inhibiting gut inflammation, and improving gut health. Keywords: microalgae, gut microbiome, animal models, clinical trials, prebiotics Downloads [Abstract] [Full Article] Published 2025-12-05 Issue Vol. 15 Keywords: gut; microalgae
• Ultra-low-dose lactulose modulates the gut microbiota in healthy adults: A double-blind, randomized, placebo-controlled crossover trial by Sakiyama, Ryo; Miyashita, Seiya; Nakano, Manabu; Tanaka, Miyuki (2025) - Keywords: Lactulose; Prebiotics; Bifidobacterium; Improving gut microbiota, Gastrointestinal health Downloads Non-digestible oligosaccharides are established prebiotics that stimulate beneficial gut bacteria; however, excessive intake may cause gastrointestinal discomfort. Keywords: gut; lactulose
• Effect of nutritionally complete formula on gut microbiota and their metabolite in fecal batch fermentation system by Wichienchot, Santad; Keawyok, Kridsada (2021) - Methods:  Fecal fermentation (in vitro) using batch culture in an environment mimicking human large intestine was used to study the change of gut microbiota by next generation sequencing (NGS) during fermentation of the developed formula (Synplus), commercial formula (Nepro®) and control. Effect of nutritionally complete formula on gut microbiota and their metabolite in fecal batch fermentation system | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Keywords: fermentation; gut; microbiota
• Modulation of gut microbiota and their metabolites by functional mulberry juice non-thermally pasteurized using microfiltration by Kaewsedam, Thitirat; Youravong, Wirote; Li, Zhenyu; Wichienchot, Santad (2022) - Modulation of gut microbiota and their metabolites by functional mulberry juice non-thermally pasteurized using microfiltration | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 9 (2022): September 2022 / Research Articles Modulation of gut microbiota and their metabolites by functional mulberry juice non-thermally pasteurized using microfiltration Authors Thitirat Kaewsedam n/a Wirote Youravong n/a Zhenyu Li n/a Santad Wichienchot n/a DOI: https://doi.org/10.31989/ffhd.v12i9.980 Abstract Background: Mulberry fruit is a source of phenolic compounds and has biological properties. Materials and methods: Functional mulberry juices were prepared with three different levels of isomaltooligosaccharide (IMO), namely 0% (MBI0), 2% (MBI2), and 8% (MBI8). Keywords: gut; mulberry

• A combination of various functional food ingredients as a weight management program: randomized, placebo-controlled, and double-blind human clinical studies by Amagase, Harunobu (2011) - For PPEE evaluation, 12 participants consumed a single bout of TAIslim System products or placebo, and took part in 6 study sessions. Negative energy balance caused by the systematic procedure (TAIslim® System), including increasing metabolic rate through physical activity, use of Lycium barbarum-containing TAIslim (Product A), and decreasing caloric intake by consuming a chewable confection (TAIslim SKINNY=Product B), and a meal replacement shake (TAIslim SHAKE=Product C), would be successful for weight loss. Keywords: placebo; system; taislim
• Clinical evaluation of a novel gallotannin-enriched Galla Rhois extract (GRE) on vital cognitive functions in healthy volunteers: A randomized, double-blind, placebo-controlled study by Heuer, Marvin; Baker, Christopher; Sedlak, Michael; Woo, Kim Jin; Kee, Kim Hyun; Bagchi, Debasis (2023) - Clinical evaluation of a novel gallotannin-enriched Galla Rhois extract (GRE) on vital cognitive functions in healthy volunteers: A randomized, double-blind, placebo-controlled study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 10 (2023): October 2023 / Research Articles Clinical evaluation of a novel gallotannin-enriched Galla Rhois extract (GRE) on vital cognitive functions in healthy volunteers: A randomized, double-blind, placebo-controlled study Authors Marvin Heuer Christopher Baker Michael Sedlak Kim Jin Woo Kim Hyun Kee Debasis Bagchi DOI: https://doi.org/10.31989/ffhd.v13i10.1213 Abstract Background: Oxidative damage has emerged as one of the significant factors in the onset of neurodegenerative disorders, primarily owing to a) higher usage of oxygen by brain cells and b) higher amounts of lipids in the neuronal membranes. Keywords: gre; issn; journal; placebo
• Effects of consuming S-allyl-L-cysteine enriched garlic extract on sleep quality in Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparative study by Hideshima, Wakana; Suzuki, Naoko; Takara, Tsuyoshi; Maru, Isafumi (2025) - Effects of consuming S-allyl-L-cysteine enriched garlic extract on sleep quality in Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparative study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 1 (2025): January 2025 / Research Articles Effects of consuming S-allyl-L-cysteine enriched garlic extract on sleep quality in Japanese adults: A randomized, double-blind, placebo-controlled, parallel-group comparative study Authors Wakana Hideshima Naoko Suzuki Tsuyoshi Takara Isafumi Maru DOI: https://doi.org/10.31989/ffhd.v15i1.1493 Abstract Introduction: Sleep promotes well-being, which includes physical and mental health, but many people suffer from sleep deprivation. One of the functional components of garlic, S-allyl-L-cysteine (SAC), can reportedly improve mental fatigue and is expected to regulate the autonomic nervous system and improve sleep quality. Keywords: placebo; sac; sleep

• Antioxidant Activity and Mechanism of Protocatechuic Acid in vitro by Li, Xican; Wang, Xiaozhen; Chen, Dongfeng; Chen, Shuzhi (2011) - Methods: In the study, the antioxidant activities of protocatechuic acid were measured in vitro using various antioxidant assays including 1,1-diphenyl-2-picryl-hydrazyl (DPPH•), 2,2’-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS+•), superoxide anion radicals (•O2-) and hydroxyl radical (•OH) scavenging activity, ferric ions (Fe3+) and cupric ions (Cu2+) reducing power, ferrous ions (Fe2+) and cupric ions (Cu2+) chelating activity, compared with the positive controls Trolox or BHT. It may exhibit antioxidant activity by both chelating metal transition ions as well as by scavenging free radicals via donating hydrogen atom (H•) or electron (e). Keywords: antioxidant; chinese
• Volatile signatures and antioxidant potentials of white mugwort (Artemisia lactiflora) extracts in emulsions: The influence of pH on functionality and stability by Kittipongpittaya, Ketinun; Panya, Atikorn; Phonsatta, Natthaporn; Puangploy, Premsak; Aoumtes, Kittipat; Sangpetch, Pennapa; Puangsawai, Nattathida; Wongkasikorn, Pimvalee (2025) - Volatile signatures and antioxidant potentials of white mugwort (Artemisia lactiflora) extracts in emulsions: The influence of pH on functionality and stability | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Volatile signatures and antioxidant potentials of white mugwort (Artemisia lactiflora) extracts in emulsions: The influence of pH on functionality and stability Authors Kittipongpittaya Ketinun Panya Atikorn Phonsatta Natthaporn Puangploy Premsak Aoumtes Kittipat Sangpetch Pennapa Puangsawai Nattathida Wongkasikorn Pimvalee DOI: https://doi.org/10.31989/ffhd.v15i9.1706 Abstract Background: White mugwort (Artemisia lactiflora), a medicinal plant native to several Asian countries, is known for its antioxidant-rich compounds and aromatic volatiles, making it a promising natural additive in food and cosmetic emulsions. Methods: Volatile compounds were analyzed using GC-MS. Keywords: antioxidant; mugwort

• Estimating peppermint essential oil levels: water-stream and classical hydroponic systems by Daryadar, Mahsa; Alexanyan, Juletta; Mayrapetyan, Stepan; Mayrapetyan, Khachatur; Tovmasyan, Anahit; Tadevosyan, Anna (2023) - The chemical content of essential oil is quite complex. The content of essential oil in flowers is 4-6%; in leaves – 2.4-2.8%, and in stems 0.3%. Keywords: hydroponics; oil; stream
• Acrylamide content and quality characteristics of French fries influenced by different frying methods by Ahmed, Zahraa Adil; Mohammed, Nameer Khairullah; Meor Hussin, Anis Shobirin (2023) - +964-7725322522 Anis Shobirin Meor Hussin Faculty of Food Science and Technology, Universiti Putra Malaysia 43400 UPM Serdang, Selangor, Malaysia DOI: https://doi.org/10.31989/ffhd.v13i6.1126 Abstract Background: This study aimed to compare the effects of three different frying methods, namely air frying (AF), microwave frying (MF), and deep frying (DF) in corn oil, on the moisture and texture, as well as the content and absorption of oil, carbohydrates and acrylamide  in French fries.  Materials and Methods: For the DF, the fresh potatoes were fully dipped in corn oil and the oil temperature was set at 160 °C for three intervals of 3, 5, and 7 minutes.  Keywords: frying; oil
• Perilla seed oil as an adjunctive treatment with statins improves lipid profiles in elderly patients: a post hoc data analysis by Chanapuk, Rapeebhorn; Mungtaweepongsa, Sombat; Sriyakul, Kusuma; Tungsukruthai, Parunkul; Pattaraarchachai, Junya; Kamalashiran, Chuntida (2023) - Our study aimed to determine if the lipid-lowering effects of P. frutescens seed oil occur on their own or alongside statin treatments by conducting a retrospective analysis of existing data to assess its efficacy in improving lipid profiles among the elderly. Conclusion: P. frutescens seed oil, particularly when used alongside statins, exhibits the potential to improve lipid profiles and may also offer liver protection. Keywords: medicine; oil; seed
• The Effect of thyme, rosemary, and lemongrass oils on extension of the shelf life and qualitative characteristics of Iraqi soft cheese by Ismael, Firas Najm; Hadi, Sara Thamer (2024) - The Effect of thyme, rosemary, and lemongrass oils on extension of the shelf life and qualitative characteristics of Iraqi soft cheese | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 1 (2024): January 2024 / Research Articles The Effect of thyme, rosemary, and lemongrass oils on extension of the shelf life and qualitative characteristics of Iraqi soft cheese Authors Firas Najm Ismael [email protected] Sara Thamer Hadi DOI: https://doi.org/10.31989/ffhd.v14i1.1262 Abstract Background: In the case of Iraqi soft cheeses, researchers have noted that the moisture content of these cheeses decreases over time in storage and reaches its maximum depletion in the final storage period. Keywords: cheese; oil
• Antimicrobial activity of moringa peregrina seed oil: chemical composition and effect of extraction procedure by Mariod, Abdalbasit Adam; Osmana, Nahla Abd Elrhman Elsayed; Ahmad, Essa Esmail Mohammad (2022) - Search Search Register Login Home / Archives / Vol. 12 No. 6 (2022): June 2022 / Research Articles Antimicrobial activity of moringa peregrina seed oil: chemical composition and effect of extraction procedure Authors Abdalbasit Adam Mariod College of Sciences and Arts-Alkamil, University of Jeddah Nahla Abd Elrhman Elsayed Osmana Department of Chemistry, Sudan University of Science and Technology, Khartoum, Sudan Essa Esmail Mohammad Ahmad aDepartment of Chemistry, Sudan University of Science and Technology, Khartoum, Sudan DOI: https://doi.org/10.31989/ffhd.v12i6.911 Abstract Background and objective: The importance of new sources of oils has recently emerged, one such source being Moringa. Antimicrobial activity of moringa peregrina seed oil: chemical composition and effect of extraction procedure | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: issn; moringa; oil

• Morinda citrifolia L. (noni) improves the Quality of Life in adults with Osteoarthritis by Wang, Mian-Ying; Lutfiyya, M. Nawal; Weidenbacher-Hoper, Vicki; Peng, Lin; Lipsky, Martin S.; Anderson, Gary (2011) - NJ has the potential to become an adjunctive therapy for OA patients. Data were collected by pre/post intervention survey and laboratory testing. Keywords: medicine; parkview avenue; rockford

• A comparative study of the effect of extracts extracted from Ocimum basilicum leaves using organic extract and essential oil by Sultan, Linh Jaafar; Fadhil, Wafaa Ghazi; Hamid, Mohammed Majid; Hadi, Sara Thamer (2024) - A comparative study of the effect of extracts extracted from Ocimum basilicum leaves using organic extract and essential oil | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 6 (2024): June 2024 / Research Articles A comparative study of the effect of extracts extracted from Ocimum basilicum leaves using organic extract and essential oil Authors Linh Jaafar Sultan Wafaa Ghazi Fadhil Mohammed Majid Hamid Sara Thamer Hadi DOI: https://doi.org/10.31989/ffhd.v14i6.1304 Abstract Background: Medicinal plants that possess antimicrobial and antioxidant properties have garnered significant attention for their role in maintaining food quality, improving safety, and impeding spoilage. Ethanolic alcohol, chloroform, and essential oil extracts were prepared; the tablets were then immersed in these solutions to test their efficacy. Keywords: extracts; issn
• Comparison of the antihypertensive effect of maguey (Agave salmiana) sap concentrate extracts by in vitro and in vivo tests by Mendoza Mendoza, Bethsua; Estrada Fernández , Ana Guadalupe ; Calderon, Zuli Guadalupe; Almaguer Vargas, Georgina ; Alanís García, Ernesto (2025) - This research demonstrates for the first time the antihypertensive effect of methanolic and butanolic extracts obtained from maguey sap concentrate, opening the possibility of using them in the production of functional foods, as well as promoting the production and consumption of maguey sap, adding value to this natural resource. For the in vivo tests, 48 male Wistar rats were divided into 6 groups: negative control (C), positive control (E): enalapril (25 mg/kg/day), BE1 and BE2: butanolic extracts (250 and 500 mg/kg/day) and ME1 and ME2: methanolic extracts (500 and 750 mg/kg/day). Keywords: extracts; issn; journal
• Almond Skin Polyphenol Extracts Stimulate the Activation of Diacylglycerol Kinase alpha via a 67 kDa Laminin Receptor by Chinthammit, Boonyaporn; Okamoto, Seika; Shirai, Yasuhito (2022) - Almond Skin Polyphenol Extracts Stimulate the Activation of Diacylglycerol Kinase alpha via a 67 kDa Laminin Receptor | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 4 (2022): April 2022 / Research Articles Almond Skin Polyphenol Extracts Stimulate the Activation of Diacylglycerol Kinase alpha via a 67 kDa Laminin Receptor Authors Boonyaporn Chinthammit Department of Agrobioscience, Graduate School of Agriculture, Kobe University, Japan Seika Okamoto Department of Agrobioscience, Graduate School of Agriculture, Kobe University, Japan Yasuhito Shirai Department of Agrobioscience, Graduate School of Agriculture, Kobe University, Japan DOI: https://doi.org/10.31989/ffhd.v12i4.894 Abstract Background: Almond skins are the byproduct of the almond industry that are rich in dietary fibers and polyphenols. Therefore, in this study, we investigated whether almond skin polyphenol extracts can also induce the activation of DGKα.  Keywords: almond; extracts

• Metabolic syndrome and the components of the Mediterranean diet by Fernandez, Maria Luz (2011) - Lfestyle factors including smoking, lack of exercise, poor dietary habits as well as low socioeconomic status are associated with the development of MetS. Diet is considered one of the major contributors to MetS. Adherence to the Mediterranean diet (high intake of whole grains, fruits and vegetables, olive oil, fish, low-fat dairy products, and moderate wine consumption) has been associated with lower prevalence of MetS. Interventions utilizing this dietary approach have proven to be successful in reducing some of the associated metabolic abnormalities. Metabolic syndrome and the components of the Mediterranean diet | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 No. 2 (2011): February 2011 / Review Articles Metabolic syndrome and the components of the Mediterranean diet Authors Maria Luz Fernandez Department of Nutritional Sciences, the University of Connecticut 3624 Horsebarn Road Extension, Storrs, CT 06269 DOI: https://doi.org/10.31989/ffhd.v1i2.142 Abstract Metabolic Syndrome (MetS) is a cluster of metabolic abnormalities known to increase heart disease risk by two-fold and type 2 diabetes risk by five-fold. Keywords: diet; journal
• Chemometric analysis of ketogenic diet formulated from low-cost dietary fibers by Kayode, Omowumi Titilola; Kayode, Abolanle A.A; Oyebode, Teniola (2022) - The developed cabbage and coconut fiber is an appropriate fiber source for ketogenic diet preparation. RESULTS: Carbohydrate content of the samples were (3.35, 4.00, 3.16 and 2.08%) for cabbage feed, coconut feed, coconut fiber, and cabbage fibers, respectively. Keywords: diet; issn; journal
• Mediterranean diet and health – a narrative review by Kaufman-Shriqui, Vered; Navarro, Daniela Abigail; Salem, Hagit; Boaz, Mona (2022) - To examine associations between adherence to the Mediterranean Diet and non-communicable disease risk. This dietary pattern has been associated with reduced risk for non-communicable diseases, including cardiovascular disease, type 2 diabetes mellitus, certain cancers, and dementia. Keywords: diet; mediterranean

• An extract from asparagus improves sleep quality and reduces sleepiness and fatigue on awakening: A pilot randomized controlled trial by Takahashi, Tsukasa; Seol, Jaehoon; Kokubo, Toshio; Goto, Kazunori; Takanari, Jun (2025) - An extract from asparagus improves sleep quality and reduces sleepiness and fatigue on awakening: A pilot randomized controlled trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 4 (2025): April 2025 / Research Articles An extract from asparagus improves sleep quality and reduces sleepiness and fatigue on awakening: A pilot randomized controlled trial Authors Tsukasa Takahashi Jaehoon Seol Toshio Kokubo Kazunori Goto Jun Takanari DOI: https://doi.org/10.31989/ffhd.v15i4.1574 Abstract Background: Good sleep is essential for a healthy, active life that supports disease prevention. Keywords: quality; sleep
• Safety and efficacy of dietary freshwater clam (Corbicula fluminea) extract in clinical research by Shimazoe, Takao; Kobayashi, Daisuke; Kawashiri, Takehiro; Chijimatsu, Takeshi; Umeki, Miki; Mochizuki, Satoshi (2022) - A sleep evaluation comparing the placebo and normal FCE dose groups was also conducted. Thus, we also assessed sleep quality after FCE intake using the Oguri-Shirakawa-Azumi (OSA) sleep inventory middle-aged and aged (MA) version and a Likert scale in a randomized controlled clinical trial.  Keywords: dose; fce; sleep

• Therapeutic potential of resveratrol, a polyphenol in the prevention of liver injury induced by diethylnitrosamine (DEN) through the regulation of inflammation and oxidative stress by RAHMANI, ARSHAD HUSAIN; Alharbi , Hajed Obaid A ; Khan, Amjad Ali ; Babiker, Ali Yousif ; Rizvi, M. Moshahid Alam (2024) - However, the group treated with RES showed hepatoprotective potential with reduced liver tissue alterations and fibrosis. Objectives: This study was designed to measure RES hepatoprotective potential against Diethylnitrosamine (DEN)-induced liver injury. Keywords: den; liver; res
• Effects of heat killed Lactiplantibacillus plantarum N1487-7 intake in humans with impaired liver function: A randomized, double-blind, placebo-controlled, parallel-group study by Uehara, Eriko; Hokazono, Hideki; Miura, Naoki (2025) - Serum levels of liver function markers such as aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-c) increase as liver function declines. Objective: To investigate the effect of oral intake of N1487-7-HK on liver function in healthy subjects with elevated serum levels of liver function markers. Keywords: function; liver; n1487
• Curcumin exerts a protective effect against obesity and liver injury induced by an atherogenic diet by Antona, María Eugenia; González, Paula Mariela; Ramos, Cecilia; Cabrera, Joaquín; Olano, Carolina; Morales, Celina; Zago, Valeria; Steimetz, Tammy; Puntarulo, Susana; Friedman, Silvia María; Macri, Elisa Vanesa (2021) - Keywords: curcumin, liver injury, ROS, atherogenic diet, visceral fat, obesity  Downloads [Abstract] [Full Article] Published 2021-12-21 Issue Vol. 11 No. 12 (2021): December 2021 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. We hypothesized that some adverse effects of consuming atherogenic or high-fat diets (AD) can be ameliorated by Cur supplementation. Keywords: cur; issn; liver
• A blend of Sphaeranthus indicus flower head and Terminalia chebula fruit extracts reduces fatty liver and improves liver function in non-alcoholic, overweight adults by Rajendra, Vamsi Krishna Pothula; Kurapati, Sridhar; Balineni, Sai Krishna; Gogineni, Naga Tejaswi Tejaswi (2022) - A blend of Sphaeranthus indicus flower head and Terminalia chebula fruit extracts reduces fatty liver and improves liver function in non-alcoholic, overweight adults | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 7 (2022): July 2022 / Research Articles A blend of Sphaeranthus indicus flower head and Terminalia chebula fruit extracts reduces fatty liver and improves liver function in non-alcoholic, overweight adults Authors Vamsi Krishna Pothula Rajendra Krishna Institute of Medical Sciences Hospital, Nellore, Andhra Pradesh Sridhar Kurapati Krishna Institute of Medical Sciences Hospital, Nellore, Andhra Pradesh Sai Krishna Balineni Aditya Multi Speciality Hospital, Guntur, Andhra Pradesh Naga Tejaswi Tejaswi Gogineni General Medicine Department, Aditya Multi Speciality Hospital, Guntur, Andhra Pradesh, India DOI: https://doi.org/10.31989/ffhd.v12i7.958 Abstract Background: Excessive accumulation of fat in the liver is a common clinical presentation in non-alcoholic fatty liver disease (NAFLD). Keywords: Non-alcoholic fatty liver disease, Fatty liver index, CL16049F1, hepatoprotective botanical formulation.   Keywords: fatty; issn; liver

• Effective body recomposition vs. misconceptions of the traditional weight loss strategies: TRCAP21 - a novel technological breakthrough in body recomposition by Bagchi, Debasis; Downs, Bernard; Banik, Samudra; Bagchi, Manashi; Kushner, Steve; Chakraborty, Sanjoy; Morrison, Bruce; Hesson, Stephen (2022) - To investigate the feasibility of doing a 90-day randomized, double-blind placebo-controlled investigation, we conducted a 21-day concept validation pilot study on TRCAP21  in 9 subjects to assess changes in various body parts, including chest, upper arms, waist/belly, hips, and thighs, as well as body weight.  Objective: This physician-supervised 21-day concept validation pilot study on TRCAP21 was conducted on 9 subjects to determine changes in anthropometric parameters including chest, upper arms, waist/belly, hips, and thighs, as well as body weight, and determine the effect of TRCAP21 on energy, mood, satiety, and sugar cravings. Keywords: body; issn; trcap21; weight

• Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases by Zibaeenezhad, Mohammad Javad; Elyaspour, Zahra (2022) - Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 11 (2022): November 2022 / Review Articles Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases Authors Mohammad Javad Zibaeenezhad Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Zahra Elyaspour Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran https://orcid.org/0000-0001-5329-6667 DOI: https://doi.org/10.31989/ffhd.v12i11.1022 Abstract Background: Intervention and epidemiological studies have shown that nut consumption has beneficial effects on cardiovascular risk factors, such as hypertension, type 2 diabetes, body mass index, and hyperlipidemia. Keywords: center; factors; shiraz
• In-vitro screening of acetylcholinesterase inhibitory activity of extracts from Palestinian indigenous flora in relation to the treatment of Alzheimer’s disease by Ali-Shtayeh, Mohammed Saleem; Jamous, Rana Majed; Abu Zaitoun, Salam Yousef; Qasem, Iman Basem (2014) - Assay of AChE activity plays an important role in vitro characterization of drugs including potential treatments for AD. Methods: The effect on AChE activity of 92 extracts of 47 medicinal plants were evaluated using a new micro-well plate AChE activity (NA-FB) and Ellman’s assays. Keywords: biodiversity; center; research
• 9-cis β-carotene Inhibits Atherosclerosis Development in Female LDLR-/- Mice by Relevy, Noa Zolberg; Rühl, Ralph; Harari, Ayelet; Grosskopf, Itamar; Barshack, Iris; Ben-Amotz, Ami; Nir, Uri; Gottlieb, Hugo; Kamari, Yehuda; Harats, Dror; Shaish, Aviv (2015) - Yehuda Kamari The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel; Sackler Faculty of Medicine, Tel-Aviv University, Israel; Dror Harats The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel; Sackler Faculty of Medicine, Tel-Aviv University, Israel; Aviv Shaish The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel DOI: https://doi.org/10.31989/ffhd.v5i2.172 Abstract Background: Several epidemiological studies have shown that diets rich in carotenoids are associated with a reduced risk of cardiovascular disease. 9-cis β-carotene Inhibits Atherosclerosis Development in Female LDLR-/- Mice | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 2 (2015): February 2015 / Research Articles 9-cis β-carotene Inhibits Atherosclerosis Development in Female LDLR-/- Mice Authors Noa Zolberg Relevy The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel; The Mina and Everard Goodman Faculty of Life Science, Bar-Ilan University, Ramat-Gan, Israel Ralph Rühl Department of Biochemistry and Molecular Biology, University of Debrecen, Debrecen, Hungary Ayelet Harari The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel Itamar Grosskopf The Bert W. Strassburger Lipid Center; Sheba Medical Center, Tel-Hashomer, 5265601 Israel Iris Barshack Institute of Pathology, Sheba Medical Center, Tel-Hashomer; Sackler Faculty of Medicine, Tel-Aviv University, Israel Ami Ben-Amotz N.B.T Israel Uri Nir The Mina and Everard Goodman Faculty of Life Science, Bar-Ilan University, Ramat-Gan, Israel Hugo Gottlieb Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel. Keywords: center; israel; tel
• Structural basis for bitter taste receptor activation and its potential role in targeting diabetes by Abrol, Ravinder; Tan, Jun; Hui, Hongxiang; Goddard III, William A.; Pandol, Stephen J. (2015) - Structural basis for bitter taste receptor activation and its potential role in targeting diabetes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 3 (2015): March 2015 / Research Articles Structural basis for bitter taste receptor activation and its potential role in targeting diabetes Authors Ravinder Abrol Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Materials and Process Simulation Center, California Institute of Technology, Pasadena, CA, USA; Jun Tan Materials and Process Simulation Center, California Institute of Technology, Pasadena, CA, USA; Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, 400030, China; Hongxiang Hui International Center for Metabolic Diseases, Southern Medical University, Guangzhou, China; Department of Medicine, University of California, Los Angeles, CA, USA William A. Goddard III Materials and Process Simulation Center, California Institute of Technology, Pasadena, CA, USA; Stephen J. Pandol Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;Department of Medicine, University of California, Los Angeles, CA, USA DOI: https://doi.org/10.31989/ffhd.v5i3.176 Abstract Background: Taste receptors are G protein-coupled receptors that, besides being present in the taste buds, have also been shown to be present in the gastrointestinal (GI) system, respiratory system, and brain, though their function at these locations is not well understood. Methods: The atomic-level structure of bitter taste receptor TAS2R38 was predicted using GEnSeMBLE, a first-principle based GPCR structure prediction method. Keywords: center; receptor; taste

• A five patient’s case study on the influence of two different probiotics on individual intestinal microbiota by Uchiyama-Tanaka, Yoko (2013) - However, as there are so many probiotics, it is unknown which probiotics might have more of an impact upon intestinal microbiota. Objective: To understand how two different types of probiotics influence human intestinal microbiota, we analyzed human fecal microbiota after taking each of the probiotics. Keywords: microbiota; probiotics

• Safety test of a supplement, 5-aminolevulinic acid phosphate with sodium ferrous citrate, in diabetic patients treated with oral hypoglycemic agents by Yamashita, Naohide; Watanabe, Atai; Kondo, Hikaru; Kawata, Satofumi; Tanaka, Tohru; Nakajima, Motowo (2014) - Safety test of a supplement, 5-aminolevulinic acid phosphate with sodium ferrous citrate, in diabetic patients treated with oral hypoglycemic agents | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 4 No. 9 (2014): September 2014 / Research Articles Safety test of a supplement, 5-aminolevulinic acid phosphate with sodium ferrous citrate, in diabetic patients treated with oral hypoglycemic agents Authors Naohide Yamashita Department of Advanced Medical Science, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Atai Watanabe Department of Advanced Medical Science, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Hikaru Kondo SBI Pharmaceuticals Co., Ltd., Tokyo, Japan Satofumi Kawata SBI Pharmaceuticals Co., Ltd., Tokyo, Japan Tohru Tanaka SBI Pharmaceuticals Co., Ltd., Tokyo, Japan Motowo Nakajima SBI Pharmaceuticals Co., Ltd., Tokyo, Japan DOI: https://doi.org/10.31989/ffhd.v4i9.151 Abstract Objective: This study aimed to examine the safety of 5-aminolevulinic acid phosphate (5-ALA) with sodium ferrous citrate (SFC) in diabetic patients treated with one or more oral hypoglycemic agents (OHAs). Keywords: ala; japan; tokyo
• Randomized, double-blind, placebo-controlled, crossover study to evaluate the effects of beta-1,3/1,6 glucan on stress associated with daily lifestyle in healthy subjects by Ojiri, Yoshihiko; Endoh, Hiroshi; Okumoto, Tadashi; Atsuta, Kazushi; Yoshinari, Orie; Moriyama, Hiroyoshi (2015) - Randomized, double-blind, placebo-controlled, crossover study to evaluate the effects of beta-1,3/1,6 glucan on stress associated with daily lifestyle in healthy subjects | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 5 (2015): May 2015 / Short Report Randomized, double-blind, placebo-controlled, crossover study to evaluate the effects of beta-1,3/1,6 glucan on stress associated with daily lifestyle in healthy subjects Authors Yoshihiko Ojiri Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan Hiroshi Endoh Faculty of Education and Graduate School of Education, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan Tadashi Okumoto Faculty of Human Health Sciences, Meio University, Nago, Okinawa 905-8585, Japan Kazushi Atsuta Chuko Awamori Distillery Co., Ltd., Tomigusuku, Okinawa 901-0235, Japan Orie Yoshinari The Japanese Institute for Health Food Standards, 6-26-12 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Hiroyoshi Moriyama The Japanese Institute for Health Food Standards, 6-26-12 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan DOI: https://doi.org/10.31989/ffhd.v5i5.179 Abstract Background: In this study, a popular and healthy beverage in Okinawa, Japan, containing a soluble baker’s yeast in black koji vinegar (Moromisu), was provided to healthy subjects with a non-strenuous daily lifestyle. Keywords: japan; stress
• Effects of taurine intake on serum lipids in young women by Matsui, Sadako; Maruyama, Chizuko; Arai, Hiroe; Hashimoto, Sachie; Asakusa, Tamami; Yoshida, Hiroshi; Ishikawa, Toshitsugu (2015) - Effects of taurine intake on serum lipids in young women | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 5 (2015): May 2015 / Research Articles Effects of taurine intake on serum lipids in young women Authors Sadako Matsui Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan Chizuko Maruyama Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan Hiroe Arai Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan Sachie Hashimoto Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan Tamami Asakusa Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681, Japan Hiroshi Yoshida Department of Laboratory Medicine, The Jikei University School of Medicine, 163-1, Kashiwashita, Kashiwa-shi, Chiba, 277-8567, Japan Toshitsugu Ishikawa Department of Nutrition and Life Science, Faculty of Applied Bioscience, Kanagawa Institute of Technology, 1030, Shimo-ogino, Atsugi, Kanagawa, 243-0292, Japan DOI: https://doi.org/10.31989/ffhd.v5i5.180 Abstract Background: Taurine is an abundant amino acid in human cells, promoting ocular and biliary health, which is also used to treat congestive heart failure, hypertension, and hepatitis. Conclusion: These results suggest that high taurine intake affects lipoprotein metabolism and increases serum lipids in slightly lean young women. Keywords: japan; taurine; women
• A water-soluble high molecular weight substance isolated from Hyuganatsu orange (Citrus tamurana), suspected to be a polysaccharide, inhibits rat osteoclast cell formation by Hata, Hiroko; Yamaguchi, Masatoshi; Sameshima, Hiroshi; Ikenoue, Tsuyomu; Matsubara, Junko; Tsuboi, Makoto; Tanaka, Takashi (2015) - Methods: We isolated five fractions from a Hyuganatsu orange extract according to molecular weight. inhibits rat osteoclast cell formation Authors Hiroko Hata Department of Obstetrics and Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki 889-1692, Japan Masatoshi Yamaguchi Department of Obstetrics and Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki 889-1692, Japan Hiroshi Sameshima Department of Obstetrics and Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki 889-1692, Japan Tsuyomu Ikenoue Department of Obstetrics and Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki 889-1692, Japan Junko Matsubara Ichimaru Phalcos Company, 318-1, Asagi, Motosu City, Gifu 501-0475, Japan Makoto Tsuboi Ichimaru Phalcos Company, 318-1, Asagi, Motosu City, Gifu 501-0475, Japan Takashi Tanaka Laboratory of Natural Product Chemistry, Nagasaki University Graduate School of Biomedical Sciences, 1-14 Bunkyo-cho, Nagasaki City, Nagasaki 852-8521, Japan DOI: https://doi.org/10.31989/ffhd.v5i6.182 Abstract Background: Osteoporosis is detrimental to aged women’s health care. Keywords: city; japan; miyazaki

• Probiotics as regulators of inflammation: A review by Lescheid, David W. (2014) - They also stimulate the differentiation and activity of important immune cells (e.g., dendritic cells, T cells), and subsequently increase production of important regulatory cytokines, including interleukin-10 (IL-10) and transforming growth factor-beta (TGF-b). In particular, by preventing or repairing ‘leaky’ epithelial barriers, probiotics can indirectly affect the inflammatory response by negating the source of pro-inflammatory stimuli associated with low-grade endotoxemia. Keywords: issn; probiotics

• In vivo evaluation of holocellulose and cellulose isolated from kumaizasa (Sasa senanensis) powder on bowel movements in rats by Hara, Hideo; Mifuru, Ryusuke; Ishikura, Yoshiro; Yokotani, Ryo; Ishida, Naobumi; Hara, Takaaki; Ozaw, Shuji (2023) - Results: Among the intervention groups (kumaizasa powder, holocellulose, cellulose group) and control group (water), no significant differences were observed with changes in body weight and food consumption. In vivo evaluation of holocellulose and cellulose isolated from kumaizasa (Sasa senanensis) powder on bowel movements in rats | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 3 (2023): March 2023 / Research Articles In vivo evaluation of holocellulose and cellulose isolated from kumaizasa (Sasa senanensis) powder on bowel movements in rats Authors Hideo Hara Ryusuke Mifuru Yoshiro Ishikura Ryo Yokotani Naobumi Ishida Clinical Support Corporation, Ltd. Takaaki Hara Shuji Ozaw DOI: https://doi.org/10.31989/ffhd.v13i3.1078 Abstract Background: Kumaizasa (Sasa senanensis Rehder) is a representative natural plant growing in Hokkaido, Japan, and has a history of being used in herbal medicine and as a health food option. Keywords: cellulose; kumaizasa; powder
• Influence of pretreatment methods and addition of fragrant plants on Gnetum gnemon var tenerum powder tea by anankarnkit, rungnapa; Muneewan, Suppakarn; Usawakesmanee, Worapong; Siripongvutikorn, Sunisa (2025) - Conclusion: The steaming-rolling treatment of Liang powder had the highest antioxidant activity, and then adding Chrysanthemum indicum L flowers powder at a ratio of 60:40 improved flavor, total polyphenol content, and antioxidant activity. The highest sensory score was recorded in tea made from a mixture of Liang leaf powder, P. amaryllifolius leaf powder, and C. indicum flower powder at a ratio of 60:0:40. Keywords: liang; powder; rolling
• Assessment of the quality of Polygonati Odorait Rhizoma powder prepared by different processes and investigation of its additive properties in steamed buns by Xu, Yao; Li, Huimin; Jia, Fan; Wu, Yuhang; Jiang, Jiani; Zheng, Hui; Zheng, Tao; He, Kai; Yang, Yong (2025) - Objective: The aim of this study was to investigate the effect of different processing methods on the physicochemical properties of PO powders, especially enzymatically modified PO powder (EM). In addition, the study investigated the additive properties of PO powder in steamed buns. Keywords: buns; powder

• Curcumin and EGCG Suppress Apurinic/Apyrimidinic Endonuclease 1 and Induce Complete Remission in B-cell Non-Hodgkin's lymphoma Patients by Bassiouny, Ahmad R.; Atteya, Mona A.; El-Rashidy, Fatma H.; Neenaa, Hashem M. (2011) - The combination of curcumin with EGCG resulted in a synergistic antitumor activity and that with CHOP agents in additivity or sub-additivity, down-regulated the expression of all NF-κB regulated gene products, leading to the suppression of angiogenesis, metastasis and entering in complete remission as indicated by β2-microglobulin and lactate dehydrogenase (LDH) levels. Objective: We examined the role of human apurinic/apyrimidinic endonuclease 1 (APE1) in resistance and prognosis in patients with FL. Keywords: curcumin; egcg; patients
• The role of curcumin in periodontal therapy: An update by Al-Kattan, Reem (2024) - The role of curcumin in periodontal therapy: An update | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 5 (2024): May 2024 / Review Articles The role of curcumin in periodontal therapy: An update Authors Reem Al-Kattan King Saud University DOI: https://doi.org/10.31989/ffhd.v14i4.1327 Abstract Background: Periodontal diseases, including gingivitis and periodontitis, present a significant global health burden, particularly affecting adults and especially the aging population. Keywords: periodontal diseases; curcumin; bioactive compounds, inflammatory response, microbial dysbiosis Downloads [Abstract] [Full Article] Published 2024-05-06 Issue Vol. 14 No. 5 (2024): May 2024 Section Review Articles License Copyright (c) 2024 Functional Foods in Health and Disease This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Keywords: curcumin; issn
• Long-term safety study of the highly absorbable curcumin formulation TS-P1 in healthy Japanese adults: a randomized, placebo-controlled, double-blind, parallel-group comparative study by Lee, Hyunjin; Kuwabara, Yoshitaka; Hirose, Akiko; Makino, Yuji; Hashimoto, Kyohei; Sakata, Misaki; Watanabe, Tadashi (2024) - Keyword: Highly bioavailable curcumin; TS-P1: Theracurmin Super; Body index (BMI); Body weight (UMIN ID: UMIN000050377) Downloads We have developed a novel curcumin formulation, TS-P1, which exhibits an 85.2-fold higher bioavailability than raw curcumin. Keywords: curcumin

• Immunodetection and quantification of insulin-like antigens in sprouts: development of an efficient functional food by Pathak, Manju; Martirosyan, Danik M. (2011) - Key words: Germination, insulin, seed embryo development, sprouts. Dry mature dormant seeds and the seeds germinated for 24 hours, 48 hours, 72 hours, and 96 hours of Glycine max, Vigna radiata and Vigna unguiculata, were investigated for expression of insulin through immunodetection using anti-insulin antibodies. Keywords: hours; insulin; issn
• A novel amino acid mixture containing isoleucine, glycine, and cystine improves insulin sensitivity with restoring mitochondrial oxygen consumption in C2C12 myotubes by Miura, Kyoko; Hasumura, Mai; Kitahara, Yoshiro; Nishitani, Shinobu; Yamada, Yoji (2025) - No. 4 (2025): April 2025 / Research Articles A novel amino acid mixture containing isoleucine, glycine, and cystine improves insulin sensitivity with restoring mitochondrial oxygen consumption in C2C12 myotubes Authors Kyoko Miura Mai Hasumura Yoshiro Kitahara Shinobu Nishitani Yoji Yamada DOI: https://doi.org/10.31989/ffhd.v15i4.1582 Abstract Background: Saturated fatty acids facilitate insulin insensitivity within peripheral tissues, which have been linked to the development of metabolic syndrome. A novel amino acid mixture containing isoleucine, glycine, and cystine improves insulin sensitivity with restoring mitochondrial oxygen consumption in C2C12 myotubes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 Keywords: amino; insulin; issn

• The protective effect of soybean phytochemicals on androgen responsive human prostate cancer cells LNCaP is likely mediated through modulation of hormone/cytokine-dependent pathways by Wang, Thomas; Boue, Stephen M.; Krishnan, Hari B. (2011) - No. 11 (2011): November 2011 / Research Articles The protective effect of soybean phytochemicals on androgen responsive human prostate cancer cells LNCaP is likely mediated through modulation of hormone/cytokine-dependent pathways Authors Thomas Wang USDA, ARS, BHNRC, Diet, Genomics, and Immunology Laboratory, Beltsville, MD 20854 Stephen M. Boue USDA, Southern Regional Research Center, New Orleans, LA 70124 Hari B. Krishnan USDA, Plant Genetics Research Unit, ARS, Columbia, MO 65211 DOI: https://doi.org/10.31989/ffhd.v1i11.113 Abstract Background: Results: Soy phytochemicals inhibit growth of androgen responsive prostate cancer cells. Keywords: pathways; soy

• Mushrooms as a functional food mediator in Preventing and ameliorating diabetes by Perera, Pathirage Kamal; Li, Yunman (2011) - The present paper reviewed scientific information on mushrooms with regards to its anti-diabetic active compounds and/or pharmacological test results, which are commonly used as functional foods and ingredients used in the traditional medical system and which have demonstrated experimental or/and clinical anti-diabetic effectiveness. Keywords: Diabetes, Mushrooms, Functional foods, Hypoglycemic, and Nutraceuticals Downloads Keywords: diabetes; issn

• Perch essence prevents cell death to improve skeletal muscle mass and strength: Evidence from in vitro and human model by Lin, Chih-Cheng; Hsieh, Chih-Yu; Chen, Ling-Ni; Lee, Mao-Hsiang; Ting, Yi-Han; Wang, Ting-Ming; Chang, Jia-Feng (2023) - No. 10 (2023): October 2023 / Short Communication Perch essence prevents cell death to improve skeletal muscle mass and strength: Evidence from in vitro and human model Authors Chih-Cheng Lin https://orcid.org/0000-0003-1842-666X Chih-Yu Hsieh Ling-Ni Chen Mao-Hsiang Lee Yi-Han Ting Ting-Ming Wang Jia-Feng Chang DOI: https://doi.org/10.31989/ffhd.v13i10.1177 Abstract Background:Fish protein supplementation may maintain muscle strength and prevent sarcopenia as it contains a complex array of macro- and micronutrients essential for building the skeletal muscle.  The cell model results demonstrated that PE could effectively prevent skeletal muscle cell from death induced by dexamethasone.  Keywords: cell; journal; muscle
• Anti-proliferative activity of yerba mate (Ilex paraguariensis) aqueous extracts on human colorectal cancer cell lines by Jason Saleh, Ali; Othman, Leen; Elchoueiry, Michel; Ghanem, Rita; Bazzi, Samer; El-Sabban, Marwan; Abdel-Massih, Roula M (2021) - Results: Cytotoxicity of aqueous yerba mate extract was studied and a dose-dependent decrease in viability was observed in all the tested cell lines. At 24 hrs., viability decreased to 19.7% with Caco-2 cells, 2.7% with HCT116, and 8.4% with HT-29 cells at a concentration of 4.8 mg/mL of yerba mate extract. Keywords: cell; mate; yerba

• Effects of γ-aminobutyric acid (GABA) intake in combination with exercise on muscle strength in humans with decreased mobility: a randomized, double-blind, placebo-controlled, parallel-group study by Uehara, Eriko; Hokazono, Hideki; Tomonaga, Akihito; Fukagawa, Mitsuhiko (2024) - Effects of γ-aminobutyric acid (GABA) intake in combination with exercise on muscle strength in humans with decreased mobility: a randomized, double-blind, placebo-controlled, parallel-group study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 4 (2024): April 2024 / Research Articles Effects of γ-aminobutyric acid (GABA) intake in combination with exercise on muscle strength in humans with decreased mobility: a randomized, double-blind, placebo-controlled, parallel-group study Authors Eriko Uehara Sanwa Shurui Co., Ltd. Hideki Hokazono Akihito Tomonaga Mitsuhiko Fukagawa DOI: https://doi.org/10.31989/ffhd.v14i4.1334 Abstract Background: Aging-related declines in skeletal muscle mass, muscle strength, and physical function are related to instability, falls, and frailty in older people, resulting in the need for nursing care. Keywords: gaba; muscle
• Effect of resistance training and lemon myrtle extract on muscle size of older adults: A pilot randomized controlled trial by Shuji Sawada; Azusa Nishino; Shinichi Honda; Yuji Tominaga; Shiori Makio; Hayao Ozaki; Shuichi Machida (2024) - This research examined the impact of combining LM extract supplementation with resistance training on muscle hypertrophy in older adults. Muscle thickness at the anterior thigh (AT) was assessed using B-mode ultrasound at baseline, 6 weeks, and 12 weeks to evaluate muscle hypertrophy. Keywords: journal; muscle

• Enhanced Antibacterial Activity of MGOTM Manuka Honey complexed with a- cyclodextrin (Manuka Honey with CycloPowerTM) by Swift, Simon; Chepulis, Lynne M.; Uy, Benedict; Radcliff, Fiona J (2014) - No. 5 (2014): May 2014 / Research Articles Enhanced Antibacterial Activity of MGOTM Manuka Honey complexed with a- cyclodextrin (Manuka Honey with CycloPowerTM) Authors Simon Swift Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland Lynne M. Chepulis Faculty of Heath, Education and Humanities, Waiariki Institute of Technology, Rotorua Benedict Uy Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland Fiona J Radcliff Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland DOI: https://doi.org/10.31989/ffhd.v4i5.13 Abstract Background: Manuka honey is recognized for it’s health-promoting properties Methods: The antibacterial properties of Manuka honey complexed with a-cyclodextrin (Manuka honey with CyclopowerTM) were compared to uncomplexed Manuka honey against a range of common organisms using standard measurements of minimum inhibitory (MIC) and bactericidal (MBC) concentrations. Keywords: auckland; honey; manuka

• Some selected properties of the recombinant aminoacylase from   Escherichia coli LGE 36 by Yepremyan, Hasmik (2024) - Keywords:  ion, metals, inhibitors, acetylmethionine, glycylmethionine, recombinant aminoacylase from Escherichia coli, enzyme. The effect of metal ions and inhibitors on the enzyme activity of recombinant intracellular aminoacylase of Escherichia coli LGE 36 was studied. Keywords: aminoacylase; coli

• Effects of the consumption of Acacia bark-derived proanthocyanidins on visceral fat: A randomized, double-blind, placebo-controlled, parallel-group comparative study by Baba, Asami; Ogawa, Sosuke; Yokosho, Kengo; Suzuki, Naoko; Takara, Tsuyoshi (2024) - Conclusions: Acacia proanthocyanidins were found to reduce visceral fat. Keywords: Acacia bark extract, proanthocyanidins, polyphenol, visceral fat, obesity Downloads [Abstract] [Full Article] [Supplementary] Published 2024-12-12 Issue Vol. 14 Keywords: acacia; fat

• Metabolic Syndrome: The Complex Relationship of Diet to Conditions of Disturbed Metabolism by Bland, Jeffrey S. (2011) - Clinical studies investigating the effects of specific phytochemicals in metabolic syndrome patients have produced encouraging results, including normalization of metabolic function, reduction of cardiovascular risk, and resolution of metabolic syndrome. Abstract The widespread prevalence and deleterious effects of metabolic syndrome have become a major public health challenge as it is associated with the development of type 2 diabetes and cardiovascular disease. Keywords: issn; metabolic
• Metabolic correction for attention deficit/hyperactivity disorder: A biochemical-physiological therapeutic approach by Mikirova, N. A.; Rogers, A. M.; Taylor, P. R.; Hunninghake, R. E.; Miranda-Massari, J. R.; Gonzalez, M. J. (2013) - Key words: Attention deficit hyperactivity disorder, metabolic correction, fatty acid composition, essential metals, toxic metals, pyrroles, vitamins and minerals. Conclusion: In the studied population it was demonstrated that metabolic correction of biochemical disturbances using essential fatty acids, amino acids, and minerals can improve fatty acid profiles and metabolic stress levels. Keywords: adhd; metabolic; patients; years

• Phytochemicals, antioxidant activity and nutritional profile of pulp, peel and peel fiber of mango (Mangifera indica l.) cultivar Ataulfo by Rocha, Rosabel; Barajas, Josefa; Quiroz, Cristobal; Cárdenas Torres, Feliznando Isidro; Terán Cabanillas, Elí; Vergara Jiménez, Marcela de Jesus (2024) - Methods: Ripe Ataulfo mango products (pulp, peel, and peel fiber) were evaluated for nutritional composition by AOAC methods. Results: Ripe Ataulfo mango products (pulp, peel, and peel fiber) were evaluated for nutritional, antioxidant, and phytochemical characteristics. Keywords: mango; peel; products
• Epigenetic effects of four nutraceutical products on human liver cells by Davis, Catherine; Davis, Paul; Gubler, Daniel (2025) - The use of nutraceutical products, either as a complement or as a substitute for pharmaceuticals, has been receiving increased attention for maintaining good health. Epigenetic effects of four nutraceutical products on human liver cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 1 (2025): January 2025 / Research Articles Epigenetic effects of four nutraceutical products on human liver cells Authors Catherine E. Davis Paul F. Davis Daniel A. Gubler DOI: https://doi.org/10.31989/ffhd.v15i1.1524 Abstract Background: There are numerous botanical extracts and fractions that have been shown to have a diverse range of bioactivities. Keywords: genes; products

• Chemical composition, physicochemical evaluation and sensory analysis of yogurt added with extract of polyphenolic compounds from Quercus crassifolia oak bark by Valencia-Avilés, Eréndira; García-Pérez, Martha Estrella; Garnica-Romo, Ma. Guadalupe; Figueroa-Cárdenas, Juan de Dios; Paciulli, Maria; Martinez-Flores, Hector Eduardo (2022) - Chemical composition, physicochemical evaluation and sensory analysis of yogurt added with extract of polyphenolic compounds from Quercus crassifolia oak bark | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 9 (2022): September 2022 / Research Articles Chemical composition, physicochemical evaluation and sensory analysis of yogurt added with extract of polyphenolic compounds from Quercus crassifolia oak bark Authors Eréndira Valencia-Avilés Programa Institucional de Doctorado en Ciencias Biológicas, Universidad Michoacana de San Nicolás Hidalgo, Ciudad Universitaria, Morelia, Michoacán, México Martha Estrella García-Pérez Ma. Universidad Michoacana de San Nicolás de Hidalgo Juan de Dios Figueroa-Cárdenas Centro de Investigación y de Estudios Avanzados del IPN. Keywords: issn; universidad; yogurt
• Effects of low lactose mare's milk yogurt consumption on gut microbiota function by Samat, Kozhakhmetov; Nurislam, Muhanbetganov; Zhanel, Pernebek; Dmitriy, Babenko; Dinar, Tarzhanova; Indira, Uyzbaeva; Zhanagul, Khassenbekova; Akmaral, Zhantureyeva; Zharkyn, Jarmukhanov; Saniya, Kozhakhmetova; Tamara, Tultabayeva; Almagul, Kushugulova (2022) - Effects of low lactose mare's milk yogurt consumption on gut microbiota function | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 8 (2022): August 2022 / Research Articles Effects of low lactose mare's milk yogurt consumption on gut microbiota function Authors Kozhakhmetov Samat National Laboratory Astana, Nazarbayev University, Nur-Sultan, Z05H0P9, Kazakhstan. Purpose of the study: To study the effect of low-lactose drinking yogurt from a combination of mare's and cow's milk on the composition and functional repertoire of the fecal microbiota of rats. Keywords: lactose; yogurt

• Yeast whey-enriched bread: nutritional profile and potential functional relevance by Bagiyan, Valeri ; Zakoyan, Anna; Verdyan, Arshaluys; Ghazanchyan, Narine; Kinosyan, Marina; Davidyan, Tamara; Harutyunyan, Baghish; Hovhannisyan, Susanna; Soghomonyan, Tigran; Goginyan, Vigen; Tsaturyan, Avetis; Chitchyan, Karine (2025) - Novelty: This work advances prototype of enriched bread development by leveraging a two-stage co-cultivation of indigenous yeast and lactic acid bacteria in whey, yielding high yeast biomass and improving shelf life and spoilage resistance versus commercial yeast controls—while maintaining comparable physicochemical quality. Objective: The study aims to isolate indigenous yeasts from ttkhmor and explore their potential for developing prototype of enriched bread for health. Keywords: bread; issn; whey; yeast
• Differential protective effects of whole and skimmed whey on LPS-induced barrier dysfunction and inflammation in Caco-2/TC7 cells by Layunta, Elena; García, Laura; Gimeno, Sofía; Martínez, Jaime; Sánchez, Lourdes; Gras, Laura (2025) - Conclusion: Both whey fractions reinforce epithelial barrier function under LPS challenge, but only whole whey (BWW) provides dual protection by also attenuating inflammatory responses. These findings support the potential of whole whey as a functional food ingredient for intestinal health by targeting both physical and immunological aspects of barrier dysfunction. Keywords: barrier; lps; whey

• The effects of dietary omega-3 polyunsaturated fatty acid supplementation on attention and impulsivity in an animal model of attention deficit/hyperactivity disorder (ADHD) by Makulska-Gertruda, Ewelina; Hauser, Joachim; Sontag, Thomas A; Lange, Klaus W (2014) - Our results regarding dietary n-3 PUFA supply may support the positive findings in human studies demonstrating that n-3 PUFA administration can improve the cognitive or behavioral symptoms in children with ADHD. A possible explanation for these results is that the attention displayed by SHR may not be linked to n-3 PUFA supply. Keywords: attention; regensburg
• Dietary omega-3 fatty acids and locomotor activity in an animal model of attention deficit hyperactivity disorder (ADHD) by Lange, Klaus W.; Makulska-Gertruda, Ewelina; Reisinger, Jakob; Sontag, Thomas-A.; Hauser, Joachim (2013) - Dietary omega-3 fatty acids and locomotor activity in an animal model of attention deficit hyperactivity disorder (ADHD) | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 6 (2013): June 2013 / Research Articles Dietary omega-3 fatty acids and locomotor activity in an animal model of attention deficit hyperactivity disorder (ADHD) Authors Klaus W. Lange Department of Experimental Psychology, University of Regensburg, 93040 Regensburg Ewelina Makulska-Gertruda Department of Experimental Psychology, University of Regensburg, 93040 Regensburg Jakob Reisinger Department of Experimental Psychology, University of Regensburg, 93040 Regensburg Thomas-A. Sontag Department of Experimental Psychology, University of Regensburg, 93040 Regensburg Joachim Hauser Department of Experimental Psychology, University of Regensburg, 93040 Regensburg DOI: https://doi.org/10.31989/ffhd.v3i6.52 Abstract Background: Attention deficit hyperactivity disorder (ADHD) is the most frequent behavioral disorder of childhood and is characterized by hyperactivity, attention problems and impulsivity. Objective: To investigate the effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on locomotor activity in the spontaneously hypertensive rat (SHR) which has been proposed as an animal model of ADHD. Keywords: regensburg; university
• Polyunsaturated fatty acids in the treatment of attention deficit hyperactivity disorder by Lange, Klaus W.; Hauser, Joachim; Kanaya, Shigehiko; Kaunzinger, Ivo; Lange, Katharina M; Makulska-Gertruda, Ewelina; Nakamura, Yukiko; Sontag, Thomas A; Tucha, Lara (2014) - Results: Dietary PUFA supplementation appears to have beneficial effects on ADHD symptoms although these effects are small. These findings suggest that PUFA supplementation may reduce the attention and behavior problems associated with ADHD. Keywords: adhd; regensburg; university

• Anti-obesity effect of Microalga, Melosira nummuloieds ethanolic extract in high-fat-diet-induced obesity C57BL/6J mice by Yun, Injue; Choi, Jiwon; Choe, Hyeonjeong; Kim, Ki-ok; Go, Gyung min; Lee, Dae-Hee; Kim, Mi-Yeon (2022) - Methods: C57BL/6J mice fed a high-fat diet (HFD) were treated over 8 weeks with Melosira ethanolic extract. Keywords: Melosira nummuloides; C57BL/6J mice; obesity: weight loss; fatty acid synthesis Downloads Keywords: journal; melosira; obesity
• Effects of fisetin on mouse lipid metabolism in vitro and in vivo by Yonesaka, Tomoaki; Yoshida, Kaoru; Iizuka, Shunsuke; Hagiwara, Hiromi (2014) - No. 10 (2014): October 2014 / Research Articles Effects of fisetin on mouse lipid metabolism in vitro and in vivo Authors Tomoaki Yonesaka Department of Biomedical Engineering, Kaoru Yoshida Biomedical Engineering Center, Toin University of Yokohama, 1614 Kurogane-cho, Aoba-ku, Yokohama 225-8502, Japan Shunsuke Iizuka Department of Biomedical Engineering Hiromi Hagiwara Department of Biomedical Engineering, DOI: https://doi.org/10.31989/ffhd.v4i10.152 Abstract Objective: The aim of this study was to investigate the anti-obesity effects of the polyphenol fisetin in 3T3-L1 preadipocytes and C57BL/6 female mice that were fed a high-fat diet (HFD). Furthermore, green tea, apple, and molokheiya polyphenols exhibit anti-obesity activities in HFD-treated obese rats or mice. Keywords: fisetin; obesity

• Agave syrup as a replacement for sucrose: An exploratory review by Yargatti, Rizwan; Muley, Arti (2022) - We explore the possibility of Agave, a native plant from Mexico, and its by-products (Agumiel, Agave syrup, etc) as a healthy alternative to sucrose in the food industry in this paper. Chemical, physical, and biological properties are explored of the two most widely used varieties (Agave Tequilana & Agave Salmiana). Keywords: agave; sucrose
• Sensory characteristics of selective traditional Indian sweets using agave syrup and stevia : An observatory study by Yargatti, Rizwan; Muley, Arti (2022) - Sensory characteristics of selective traditional Indian sweets using agave syrup and stevia : An observatory study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 12 (2022): December 2022 / Research Articles Sensory characteristics of selective traditional Indian sweets using agave syrup and stevia : An observatory study Authors Rizwan Yargatti Arti Muley DOI: https://doi.org/10.31989/ffhd.v12i12.1042 Abstract Background:   Indian sweets largely contribute to the rising graph of obesity and cardiovascular diseases in India. Replacement of sucrose with natural sweeteners in traditional Indian sweets is one way of dealing with the consequences of high sucrose consumption. Keywords: sucrose; sweets

• Glycemic Index values of some Jaffna fruits by Pirasath, Selladurai; Thayananthan, Kulasingam; Balakumar, Sandrasekarampillai; Arasaratnam, Vasanthy (2012) - Conclusion: The three varieties of plantains and papaya were low GI fruits, and jack fruit was found to be an intermediate GI fruit. Scientific data on glycemic index values of common meals is essential to modify the diets for diabetes mellitus patients. Keywords: fruits; issn; jaffna
• Assessment of vitamin- and mineral-content stability of tomato fruits as a potential raw material to produce functional food by Irina, Zharkova; Irina, Pochitskaya; Dmitriy, Efremov; Inessa, Plotnikova; Alla, Chusova; Alena, Pronkina; Natalya, Harutyunyan (2024) - Assessment of vitamin- and mineral-content stability of tomato fruits as a potential raw material to produce functional food | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 1 (2024): January 2024 / Research Articles Assessment of vitamin- and mineral-content stability of tomato fruits as a potential raw material to produce functional food Authors Zharkova Irina Pochitskaya Irina Efremov Dmitriy Plotnikova Inessa Chusova Alla Pronkina Alena Harutyunyan Natalya DOI: https://doi.org/10.31989/ffhd.v14i1.1259 Abstract Background: Tomatoes are a valuable source of biologically active substances (vitamin C, lycopene, lutein, macro- and microelements) and can be used to produce functional foods. Keywords: bull; fruits; heart

• Study of changes of antioxidant activity during fermentation of various types of legumes as a possible functional food ingredient by Kim, Anastasia; Balanov, Petr; Smotraeva, Irina (2024) - We found that DAG ingestion increases plasma serotonin levels by approximately 50% compared to TAG ingestion. Up-regulated mRNA expressions associated with EE by DAG in the small intestine may explain increased postprandial EE. Keywords: dag; mog; serotonin

• Proximate composition and sensory attributes of gluten-free pasta made from jackfruit seeds by Thatsanasuwan, Natthaphon; Duangjai, Acharaporn; Suttirak, Pannatat; Phanthurat, Naritsara (2023) - The addition of jackfruit seeds resulted in a reduction in the flavour, cohesiveness, taste, and colour characteristics compared to wheat flour pasta. Replacing wheat flour with jackfruit seeds in pasta represents a potential alternative food for those with gluten sensitivities. Keywords: pasta; phayao

• Interim report from a 2-year double-blind rct testing fermented papaya preparation on immune enhancement, endothelial health and qol in elderly adults by Lorenzetti, Aldo; Osato, Maki; He, Fang; Aperio, Cristiana; Ayala, Antonio; Rasulova, Saida; Barbagallo, Mario (2023) - There was also at significant and comparable positive effect for time on vitality shown in both AA and FPP® groups. ADMA values were not affected by AA supplementation whereas FPP® treatment was associated with a significant decrease beginning with observation during Visit III (P<0.05 vs baseline and vs AA administration). Keywords: fpp; issn

• Maternal EGCG intervention mitigates chronic hypertension during pregnancy in spontaneously hypertensive rats without adverse effects on pregnancy outcomes by Shao, Yang; Lee, Siew-Keah; Chua, Ang-Lim; Chew, Yik-Ling; Liew, Kai Bin (2024) - Objective: This study aims to investigate the effects of maternal EGCG supplementation on elevated blood pressure and pregnancy outcomes in a rodent model of chronic hypertension, specifically using spontaneously hypertensive rats (SHR). Maternal EGCG intervention mitigates chronic hypertension during pregnancy in spontaneously hypertensive rats without adverse effects on pregnancy outcomes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 11 (2024): November 2024 / Research Articles Maternal EGCG intervention mitigates chronic hypertension during pregnancy in spontaneously hypertensive rats without adverse effects on pregnancy outcomes Authors Yang Shao Siew-Keah Lee Ang-Lim Chua Yik-Ling Chew Kai Bin Liew DOI: https://doi.org/10.31989/ffhd.v14i11.1453 Abstract Background: Chronic hypertension during pregnancy is a significant concern, associated with increased risks of maternal-fetal morbidity and mortality. Keywords: egcg; hypertension; pregnancy

• The effects of Dyglomera (Dichrostachys glomerata extract) on body fat percentage and body weight: a randomized, double- blind, placebo-controlled clinical trial by Youovop, Janvier; Takuissu, Guy; Mbopda, Christelle; Nwang, Felix; Ntentié, Raissa; Mbong, Mary-Ann; Azantsa, Boris; Singh, Harinder; Oben, Julius (2023) - The effects of Dyglomera (Dichrostachys glomerata extract) on body fat percentage and body weight: a randomized, double- blind, placebo-controlled clinical trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 6 (2023): June 2023 / Research Articles The effects of Dyglomera (Dichrostachys glomerata extract) on body fat percentage and body weight: a randomized, double- blind, placebo-controlled clinical trial Authors Janvier Youovop Guy Takuissu Ministry of Scientific Research, Cameroon Christelle Mbopda Felix Nwang Raissa Ntentié Mary-Ann Mbong Boris Azantsa Harinder Singh Julius Oben DOI: https://doi.org/10.31989/ffhd.v13i6.1088 Abstract Introduction: Previous studies have shown the beneficial effects of Dyglomera®, a hydroethanolic extract of Dichrostachys glomerata, on inflammation as well as parameters linked to metabolic syndrome. Keywords: Dichrostachys glomerata, Dyglomera®, body fat percentage, body weight, clinical trials. Keywords: body; dyglomera; fat

• Biofilm formation and auto-aggregation abilities of novel targeted aqua-probiotics by Manvelyan, Anahit; Balayan, Marine; Miralimova, Shakhlo; Chistyakov, Vladimir; Pepoyan, Astghik (2023) - 1R, Bacillus amyloliquefaciens str. 4R, Bacillus amyloliquefaciens str. Keywords: bacillus; biofilm; str
• Heat-inactivated Bacillus subtilis subsp. natto strain QOL (QOLbacillus natto) improves negative mood states: A randomized,double-blind, and placebo-controlled parallel study by Nakamura, Naoki; Sano, Yuichi; Suzuki, Naoko; Takara, Tsuyoshi (2025) - QOL bacillus natto has been reported to improve sleep quality in healthy adults, and to improve depression-like behavior caused by social defeat stress in animal models. However, there is a lack of research investigating the effects of QOL bacillus natto on psychological stress related to desk work. Keywords: bacillus; natto; qol

• In Vitro Regulation of Enzymes of the Renin-angiotensin-aldosterone System by Isoquercitrin, Phloridzin and their Long Chain Fatty Acid Derivatives by Bhullar, Khushwant S; Ziaullah, Ziaullah; Rupasinghe, Vasantha (2014) - The potential use of PZ derivatives as natural health products to treat hypertension needs to be further evaluated. Objective: The current study is designed to investigate the antihypertensive activity of isoquercitrin (quercetin-3-O-glucoside, Q3G) and phloridzin (PZ) in comparison to their twelve long chain fatty acid derivatives via enzymatic inhibition of renin angiotensin aldosterone system (RAAS) enzymes. Keywords: fatty

• Evaluation of the antioxidant activity and nitric oxide production effect of formulated crispy vegetables from thermal processing of Amaranthus viridis and Sauropus androgynous by Madardam, Juwainee; Wattanachant, Saowakon; Yupanqui, Chutha Takahashi (2023) - Methods: A. viridis and S. androgynous fresh vegetable leaves were dried, processed and formulated into crispy vegetables: A. viridis crispy vegetables, S. androgynous crispy vegetables and 50:50% (w/w) mixture of A. viridis and S. androgynous  crispy vegetables. Results: S. androgynous crispy vegetable had higher phenolic (36.55 ± 0.01 mg GAE/g) and flavonoid (81.17±0.00 mg QE/g) contents than A. viridis crispy vegetables (16.55±0.00 mg GAE/g and 40.58±0.01 QE/g respectively) and 50:50% mixed crispy vegetable formula of A. viridis and S. androgynous (26.01 ± 0.00 mg GAE/g; 59.38±0.00 QE/g respectively). Keywords: crispy; vegetables
• Phytochemicals in commonly consumed foods in malawian diets by Ndolo, Victoria; Maoni, Margaret; Mwamatope, Bonface; Tembo, David Tryson (2022) - TPC of uncooked vegetables ranged from 522.22 mgGAE/g (pumpkin leaves) to 33, 684.66 mgGAE/g (ntoriro), while in cooked vegetables it ranged from 135.93 mgQE/g (bonongwe) to 6817.86 mgQE/g (chisoso). Objective of the study: The aim of this research was to screen phytochemicals in commonly consumed fruits and vegetables in Malawi. Keywords: malawi; phytochemicals; university; vegetables

• Wound healing activity of Ipomoea batatas tubers (sweet potato) by Panda, Vandana; Sonkamble, Madhav; Patil, Swati (2011) - To check their effects on wound healing, the peels and peel bandage were tested on various injury models in rats in the present study. Methods: The methanolic extracts of the peels and peel bandage of Ipomoea batatas tubers (sweet potato) were screened for wound healing by excision and incision wound models on Wistar rats. Keywords: issn; peel; wound

• Unlocking the potential of carrot pomace: Enzymatic and impact-disintegrator-activator processing for elevated beta-carotene concentration in carrot powder by Baskovtceva, Angelina; Barakova, Nadezhda; Samodelkin, Evgeniy; Kiprushkina, Elena; Alkhateeb, Reem; Tochilnikov, Grigory (2023) - Unlocking the potential of carrot pomace: Enzymatic and impact-disintegrator-activator processing for elevated beta-carotene concentration in carrot powder | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 10 (2023): October 2023 / Research Articles Unlocking the potential of carrot pomace: Enzymatic and impact-disintegrator-activator processing for elevated beta-carotene concentration in carrot powder Authors Angelina Baskovtceva Nadezhda Barakova Evgeniy Samodelkin Elena Kiprushkina Reem Alkhateeb Grigory Tochilnikov DOI: https://doi.org/10.31989/ffhd.v13i10.1184 Abstract Backgrounds: Carrot pomace is a by-product of the juice industry, which quickly spoils due to its high moisture content and is usually considered waste. Context and purpose of this study:In this study, we aimed to develop a technology for obtaining carrot powder from carrot pomace with an increased availability of beta-carotene. Keywords: carrot; processing

• Anti-jugular vein thrombotic effect of Morinda citrifolia L. [noni] in male SD rats by Ayanbule, Funmi; Li, Guodong; Peng, Lin; Nowicki, Jacob; Anderson, Gary; Wang, Mian-Ying (2011) - The mechanisms for anti-venous thrombotic effects of NJ needs further study. Anti-venous thrombotic activities of 5% NJ, 10% NJ, heparin, and 10% NJ plus heparin were examined and compared with the positive and blank controls. Keywords: heparin; rockford

• Efficacy of an iron-fortified gummy on iron-deficiency anemia in young women by Xiao, Yan; Yang, Bingjie; Ni, Jiayi; Hu, Ran (2024) - Conclusion:Daily consumption of the iron-fortified gummy over eight weeks could help build up blood iron levels to generate hemoglobin, relieve iron-deficiency anemia and related symptoms in young Chinese women. Intake of iron through gummy on a daily basis is an effective method to gradually increase the participants’ iron levels, leading to sustainable long-term benefits. Keywords: gummy; iron; issn

• Effect of dietary fiber in lowering serum glucose and body weight in sprague dawley rats by Butt, Masood Sadiq; Shahzadi, Naureen; Suleria, Hafiz; Sultan, Tauseef; Chohan, Muhammad Imran (2011) - Effect of dietary fiber in lowering serum glucose and body weight in sprague dawley rats | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 1 No. 8 (2011): August 2011 / Research Articles Effect of dietary fiber in lowering serum glucose and body weight in sprague dawley rats Authors Masood Sadiq Butt National Institute of Food Science and Technology, University of Agriculture Faisalabad Naureen Shahzadi National Institute of Food Science and Technology, University of Agriculture Faisalabad Hafiz Suleria National Institute of Food Science and Technology, University of Agriculture Faisalabad Tauseef Sultan National Institute of Food Science and Technology, University of Agriculture Faisalabad Muhammad Imran Chohan National Institute of Food Science and Technology, University of Agriculture Faisalabad DOI: https://doi.org/10.31989/ffhd.v1i8.124 Abstract Introduction: The present study evaluated the hypoglycemic perspectives and weight loss significance of dietary fiber. Keywords: guar; gum; rats

• In vitro assessment of thrombolytic potential of red and white ginger (Zingiber officinale) by Pinontoan, Reinhard; Leke, Patricia Ansyra Injilia; Lesmana, Jevon Aaron; Purnomo, Jonathan Suciono; Dikson, Dikson; Samantha, Ariela (2024) - Results: Red and white ginger extracts were found to have strong thrombolytic properties via high total liberated erythrocyte count from the erythrocyte liberation assay. rubrum) and white ginger (Zingiber officinale var. Keywords: ginger; issn; pelita

• Metabolic syndrome among obese patients attending the medical clinics of the three teaching hospitals at Sana’s City, Yemen by Bamashmoos, Mohammed A.; Al Serouri, Abdul W. (2011) - Conclusion: Prevalence of MS is high among obese Yemeni patients and high BP was the commonest co-morbidity. 85 mm Hg or on treatment for high BP, fasting glucose ≥110 mg/dl or on diabetes treatment, triglycerides ≥150 mg/dl, and HDL cholesterol <40 mg/dl in men and <50 mg/dl in women. Keywords: issn; journal; obese

• Atractylodin, β-eudesmol, and (+)-hinesol in Atractylodes chinensis rhizomes improve glomerular injuries in high immunoglobulin A mice by Nishizawa, Mikio ; Ishii, Toshinari; Nishidono, Yuto; Shirako, Saki; Tanaka, Ken; Ikeya, Yukinobu (2024) - Objective: The aim of this study is to identify the compounds that reduce IgA deposition in an EtOAc-soluble fraction of A. chinensis rhizomes. A standard diet including each compound was fed to HIGA and BALB/c mice for 20 weeks to evaluate the improvement of glomerular IgA deposition. Keywords: chinensis; iga; mice
• Correction of metabolic disturbances by functional food compositions in experimental obesity in CD-1 and agouti-yellow mice by Lebedev, Petr; Peresypkina, Anna; Gustinovich, Vasiliy; Godunov, Oleg; Gustinovich, Vladimir; Zatolokina, Maria; Goliusov, Artem; Pokrovskii, Mikhail (2022) - Correction of metabolic disturbances by functional food compositions in experimental obesity in CD-1 and agouti-yellow mice | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 1 (2022): January 2022 / Research Articles Correction of metabolic disturbances by functional food compositions in experimental obesity in CD-1 and agouti-yellow mice Authors Petr Lebedev Anna Peresypkina Belgorod State National Research University https://orcid.org/0000-0003-2829-9860 Vasiliy Gustinovich Oleg Godunov Vladimir Gustinovich Maria Zatolokina Artem Goliusov Mikhail Pokrovskii DOI: https://doi.org/10.31989/ffhd.v12i1.874 Abstract Background:  To determine the most promising composition, the possibility of correction of metabolic disturbances was investigated with the use of functional food compositions in CD1 and agouti-yellow mice in experimental obesity. Keywords: composition; groups; mice

• Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension by Nileeka Balasuriya, B. W.; Vasantha Rupasinghe, H. P. (2011) - As the over expression of RAAS is associated with vascular hypertension, ACE inhibition has become a major target control for hypertension. The results also revealed that the major contributing compounds of ASE for ACE inhibition belong to flavonoids. Keywords: ace; flavonoids; inhibition
• Flavonoids and phenolic acids from pearl millet (Pennisetum glaucum) based foods and their functional implications by Nambiar, Vanisha S.; Sareen, Neha; Daniel, Mammen; Gallego, Erick B. (2012) - Five phenolic acids were identified: namely vanilic acid, syringic acid, melilotic acid, para-hydroxyl benzoic acid, and salicylic acid. Flavonoids and phenolic acids from pearl millet (Pennisetum glaucum) based foods and their functional implications | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 Keywords: flavonoids; millet; pearl

• Safety evaluation of excessive intake of Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex in Healthy Japanese Subjects by Moriwaki, Masamitsu; Abe, Aya; Kapoor, Mahendra P; Yamaguchi, Akiko; Okamoto, Saki; Ozeki, Makoto (2024) - Search Search Register Login Home / Archives / Vol. 14 No. 3 (2024): March 2024 / Research Articles Safety evaluation of excessive intake of Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex in Healthy Japanese Subjects Authors Masamitsu Moriwaki TAIYOKAGAKU Co.,LTD Aya Abe TAIYOKAGAKU Co.,LTD Mahendra P Kapoor TAIYOKAGAKU Co.,LTD Akiko Yamaguchi TAIYOKAGAKU Co.,LTD Saki Okamoto TAIYOKAGAKU Co.,LTD Makoto Ozeki TAIYOKAGAKU Co.,LTD DOI: https://doi.org/10.31989/ffhd.v14i3.1325 Abstract Background: Hesperidin, a flavonoid glycoside, is widely found in the peels and rinds of citrus fruits, offering various physiological benefits. Safety evaluation of excessive intake of Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex in Healthy Japanese Subjects | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: co.; hcd
• Effect of a dietary supplement containing kurozu (a Japanese traditional health drink) concentrate on several obesity-related parameters in obese Japanese adults: a randomized, double-blind, placebo-controlled trial by Hamadate, Naobumi; Nakamura, Ken-ichiro; Hirai, Motoko; Yamamoto, Tetsuro; Yamaguchi, Hideyo; Iizuka, Muneaki; Yamamoto, Etsushi; Iwama, Yoshitaka; Yazawa, Kazunaga (2013) - Conclusion: Although the results are not definitive, KC supplementation may have potential for improving some obesity-related parameters in obese subjects, particularly females. This study was undertaken to examine the Kurozu concentrate (KC) based dietary supplement on several obesity-related parameters in obese Japanese male and female adults. Keywords: co.; ltd

• Monoglucosyl rutin, a flavonoid glycoside, improves low-density lipoprotein-cholesterol levels in healthy adults: A randomized controlled trial by Hashizume, Yushi; Tandia, Mahamadou (2024) - The reduction in LDL-C levels coincided with statistically significant decreases in total cholesterol levels, non HDL-C levels, and the LDL-C/HDL-C ratio. Results: There were 54 (27 in each group) participants in the per-protocol set (PPS) and 53 (placebo group, 26; MR group, 27) participants in the modified PPS (mPPS). Keywords: cholesterol; levels
• Effect of Mixed-Tocotrienols in Hypercholesterolemic Subjects by Yuen, Kah Hay; Wong, Jia Woei; Lim, Ai Beoy; Ng, Bee Hong; Choy, Wai Peng (2011) - Keywords: tocotrienols, cholesterol-lowering, total cholesterol, LDL cholesterol, tocopherols Downloads On the other hand, the serum cholesterol, total tocotrienol and α-tocopherol concentrations of subjects in the placebo group remained essentially unchanged. Keywords: cholesterol; university

• Cerebrovascular and antihyperlipidemic properties of sour cherry (Prunus cerasus) fruit by Knarik, Shamilyan; Hakob, Topchyan; Arusyak, Zhamharyan; Varduhi, Poghosyan; Artur, Melkonyan; Melina, Avetyan; Marine, Balasanyan (2025) - Objectives: The purpose of this observation was to investigate the antihyperlipidemic activity and discover the new cerebrovascular effects of sour cherry fruits. Assessment of sour cherry fruits on triglyceride levels showed a significant reduction on days 7 and 14 by 17.86 ± 5.57% and 21.01 ± 9.25%, respectively, compared to baseline. Keywords: cherry; issn; levels

• Antioxidant activity of fractionated pigmented Thai Hawm Gra Dang Ngah 59 rice bran hydrolysates: Pretreatment-assisted enzymatic extraction by Panomwan, Pornpen; Tatiyaborworntham, Nantawat (2024) - Keywords: Thai Hawm Gra Dang Ngah 59 rice bran, fractionated rice bran hydrolysates, pretreatment-assisted enzymatic extraction, antioxidant activity Downloads [Abstract] [Full Article] Published 2024-06-21 Issue Vol. 14 The whole RBH and three MW fractions were assessed to determine protein yield, protein recovery, total phenolic content, and the following antioxidative assays: 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ferrous ion chelating activity, and ferric ion reducing antioxidation power (FRAP). Keywords: bran; hgdn; rice

• Some parameters of hydroponic and soil Rhubarb cultivated in the Ararat Valley of Armenia by Daryadar, Mahsa; Matevosyan, Artur; Roosta, Hamid; Ghorbanpour, Mansour; Stepanyan, Anjelika; Ghahramanyan, Aristakes; Tadevosyan, Anna (2024) - Total titratable acidity showed seasonal variations: the highest acidity (1.2 to 1.3-fold higher) of hydroponic rhubarb juice was observed in July compared to other months. The research focuses on identifying the optimal growth period to maximize key quality indicators of rhubarb stalks and juice for food and medicinal applications: Brix value, juice density, total titratable acidity, and vitamin C content. Keywords: issn; rhubarb; soil
• The study of biologically active compounds and gross β-radioactivity of some vegetables and medicinal plants in conditions of outdoor hydroponic systems and soil culture in Ararat Valley by Ghalachyan, Laura; Mairapetyan, Stepan; Tadevosyan, Anna; Hovhannisyan, Lusya; Vardanyan, Anush; Mairapetyan, Khachatur; Daryadar, Mahsa; Siseryan, Ruben; Tovmasyan, Anahit ; Stepanyan, Anjelika; Asatryan, Armenuhi; Hakobjanyan, Anahit (2024) - The study of biologically active compounds and gross β-radioactivity of some vegetables and medicinal plants in conditions of outdoor hydroponic systems and soil culture in Ararat Valley | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 8 (2024): August 2024 / Research Articles The study of biologically active compounds and gross β-radioactivity of some vegetables and medicinal plants in conditions of outdoor hydroponic systems and soil culture in Ararat Valley Authors Laura Ghalachyan Stepan Mairapetyan Anna Tadevosyan Lusya Hovhannisyan Anush Vardanyan Khachatur Mairapetyan Mahsa Daryadar Ruben Siseryan Anahit Tovmasyan Anjelika Stepanyan Armenuhi Asatryan Anahit Hakobjanyan DOI: https://doi.org/10.31989/ffhd.v14i8.1415 Abstract Background: It is known that various natural (40K, 234Th, 231Th, etc.) and technogenic (90Sr, 89Sr, 137Cs, 134Cs, etc.) radionuclides (RN) may enter into the biosphere during the operation of nuclear power plants (NPP). Thus, monitoring the gross β-radioactivity of plant materials (such as vegetables, medicinal plants, fruits, etc.) and ensuring the production of radioecologically safe plant raw materials is a contemporary challenge. Keywords: plant; radioactivity; soil

• Effects of sour cherry fruits on platelet aggregation and arterialblood pressure by Knarik, Shamilyan; Hakob, Topchyan; Arusyak, Zhamharyan; Varduhi, Poghosyan; Taguhi, Pstikyan; Melina, Avetyan ; Arthur, Melkonyan; Marine, Balasanyan (2024) - Systolic blood pressure values after administration of Sour Cherry fruits began reducing from the 10th minute of the experiment and reached maximal reduction at the 40th minute by 15.3%. Conclusion: The presented investigation proves Sour Cherry fruits as functional foods with antiplatelet and antihypertensive effects which opens up perspectives in the search for new, safe agents in the prevention and treatment of cardiovascular diseases and stroke based on functional food properties. Keywords: cherry; issn; minute

• A combination of multi-strain probiotics, prebiotic, and plant extracts improves ethanol-induced hangover outcomes in a zebrafish model by Ou, Yangwenshan; Zhang, Weiguo; Lan, Jiaxun; Huang, Xiaodan; Li, Nan (2024) - Objective: Our main goal is to assess behavioral responses and alcohol metabolism in zebrafish treated with a combination of multi-strain probiotics, prebiotic, and plant extracts after ethanol administration. No. 10 (2024): October 2024 / Research Articles A combination of multi-strain probiotics, prebiotic, and plant extracts improves ethanol-induced hangover outcomes in a zebrafish model Authors Yangwenshan Ou Weiguo Zhang Jiaxun Lan Xiaodan Huang Nan Li DOI: https://doi.org/10.31989/ffhd.v14i10.1462 Abstract Background: Alcohol use, even in moderation, causes hangover discomforts. Keywords: ethanol; plant

• Dietary intake of sulforaphane-rich broccoli sprouts decreases fecal calprotectin levels in patients with ulcerative colitis by Yanaka, Akinori; Ohmori, Toshihide; Ochi, Masanori; Suzuki, Hideo (2024) - In this study, we examined if dietary intake of sulforaphane-rich broccoli sprouts decreases fecal calprotectin levels in patients with ulcerative colitis Methods: This study was registered with the University hospital Medical Information Network (UMIN) in Japan under the Clinical Trial Registration Number, UMIN000041972. Sulforaphane, which is abundant in broccoli sprouts (BS), has been shown to enhance antioxidant activity by up-regulating nrf2-mediated antioxidant enzymes. Keywords: sprouts; sulforaphane
• Steamed broccoli sprouts diet alleviates inflammatory bowel disease by increasing anti-inflammatory, antioxidant, and gut protective metabolites in an ulcerative colitis mouse model by Alaba, Tolu; Zhang, Tao; Li, Yanyan; Ishaq, Suzanne (2025) - Steamed broccoli sprouts diet alleviates inflammatory bowel disease by increasing anti-inflammatory, antioxidant, and gut protective metabolites in an ulcerative colitis mouse model | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 5 (2025): May 2025 / Research Articles Steamed broccoli sprouts diet alleviates inflammatory bowel disease by increasing anti-inflammatory, antioxidant, and gut protective metabolites in an ulcerative colitis mouse model Authors Tolu E. Alaba Tao Zhang Yanyan Li Suzanne L. Ishaq DOI: https://doi.org/10.31989/ffhd.v15i5.1603 Abstract Background: Broccoli is a cruciferous vegetable rich in bioactive compounds that may be beneficial against inflammatory bowel disease. Conclusions: These data suggest that broccoli sprouts may positively affect metabolites and microbial interactions. Keywords: broccoli; metabolites; sprouts

• Mineral composition and antioxidant activity of partially digested coffee “Kopi Luwak” by Ismayawati, Ayu Diawi; Yokoyama, Daigo; Goto, Ryui; Oya, Yuki; Watanabe, Izumi; Horai, Sawako; Sakakibara, Hiroyuki (2024) - Methods: Twenty-one regular type of coffee bean and 17 of Kopi Luwak bean were purchased from local markets or Kopi Luwak production company in Indonesia.  Results: Of these 23 minerals, the concentrations of Mn and Ba were significantly lower in Kopi Luwak than in regular coffee. Keywords: coffee; kopi; luwak
• Processed coffee alleviates DSS-induced colitis in mice by Fiebich, Bernd L.; Vinuesa, Amaya G.; Sanchez-Duffhues, Gonzalo; Collado, Juan A.; Rose, Thorsten; Menthe, Jörn; Muñoz, Eduardo (2013) - Objectives: The aim of this study was to study the anti-inflammatory and gastro-protective effects of processed coffee (Idee-Kaffee) on in LPS-treated human primary monocytes and in a murine model of colon inflammation (IBD model). Conclusions: This work identified processed coffee as an anti-inflammatory beverage with the capacity to reduce substantially DSS-induced colitis as well as the colitis-associated cellular inflammatory events. Keywords: coffee; córdoba

• Heat-killed Lactiplantibacillus plantarum N1487-7 induces IL-10 production and enhances skin barrier function by Uehara, Eriko; Hokazono, Hideki (2024) - plantarum N1487-7 (N1487-7-HK) on IL-10 production in Caco-2 cells and macrophages, and skin barrier function in physically stressed mice was investigated. Interleukin (IL)-10, an anti-inflammatory cytokine, suppresses the release of inflammatory cytokines, such as IL-6, and inhibits the decline in skin barrier function. Keywords: il-10; n1487

• Effects of 5-aminolevulinic acid on production of antibodies against classical swine fever live vaccine by Kobayashi, Eiji (2021) - Next, using male micro miniature pigs, the change in body weight was measured from the time before inoculation with the live vaccine to 28 days after inoculation, and the pattern of IgM and IgG antibody production after 5-ALA administration was examined.  The CSF vaccine had a low inducing effect on antibody production in females, which improved after administration of 5-ALA by enhancing Th2 immunity as indicated by elevated interleukin-10 levels. Keywords: ala

• Novel ELISA technology in assessing undenatured type II collagen in functional foods and dietary supplements used for knee joint health care: its sensitivity, precision, and accuracy by Shiojima, Yoshiaki; Moriyama, Hiroyoshi; Takahashi, Megumi; Takahashi, Ryohei; Maruyama, Kazuo; Bagchi, Manashi; Bagchi, Debasis (2022) - Keywords: Undenatured type II collagen, NEXT-II®, ELISA method, Pepsin Downloads [Abstract] [Full Article] Published 2022-05-13 Issue Vol. 12 No. 5 (2022): May 2022 Section Short Report License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Novel ELISA technology in assessing undenatured type II collagen in functional foods and dietary supplements used for knee joint health care: its sensitivity, precision, and accuracy | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: collagen; tokyo; type

• Phenolic compounds and antimicrobial activity of extracts ofapricot leaves derived from the trees treated with pesticides by Grigoryan, Anna; Mirzoyan, Varsik; Hanisyan, Ruzanna; Sahakyan, Naira; Karapetyan, Tamara (2024) - Phenolic compounds and antimicrobial activity of extracts ofapricot leaves derived from the trees treated with pesticides | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 12 (2024): December 2024 / Research Articles Phenolic compounds and antimicrobial activity of extracts ofapricot leaves derived from the trees treated with pesticides Authors Anna M. Grigoryan Varsik S. Mirzoyan Ruzanna M. Hanisyan Naira Zh. Keywords: compounds; issn; leaves
• Enhancing the functional value of watermelon through study of bioactive compounds and grafting potential in Armenia by Martirosyan, Gayane ; Avagyan, Alvina; Mavlyanova, Ravza; Sargsyan, Gayane; Harutunyan, Zara; Terteryan, Hasmik; Nazaretyan, Aregnaz; Santrosyan, Gagik; Vardanian, Iryna (2025) - Objective: This study aimed to evaluate the impact of grafting on watermelon yield, disease resistance, and the content of key bioactive compounds, with the goal of enhancing its functional value. Enhancing the functional value of watermelon through study of bioactive compounds and grafting potential in Armenia | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 Keywords: compounds; grafting; issn; watermelon

• Pharmacochemical investigation of Rosmarinus officinalis L. cultivated by clonal micropropagation and hydroponic combined method by Vardanyan, Anush; Mairapetyan, Stepan; Tadevosyan, Anna; Asatryan, Armenuhi; Matevosyan, Artur; Ghalachyan, Laura (2025) - Vitamin C content was 1.3 times higher in hydroponic plants of R. officinalis than in soil-grown plants, while the content of β-carotene showed no significant differences. Conclusion: The combined method of clonal micropropagation and hydroponics can produce healthy rosemary plant material, which can serve as a rich source of BAC and essential oil for use in antioxidant herbal teas, spices, food supplements, cosmetics, etc. Keywords: officinalis; plants; rosemary; аnd
• The effect of different growth conditions on the content of bioactive compounds and gross β-radioactivity of some wild edible plants in the Republic of Armenia by Ghalachyan, Laura; Daryadar, Mahsa; Matevosyan, Artur; Roosta, Hamid; Ghorbanpour, Mansour; Ghahramanyan, Aristakes; Stepanyan, Anjelika; Tadevosyan, Anna (2025) - Methods: Total protein content was assessed using the Kjeldahl method, and tannin content was determined using a titrimetric method, while the total flavonoid content was quantified using a spectrophotometric method. The minimum flavonoid and tannin content in rhubarb petioles was recorded at 0.75N (0.2% and 2.1%, respectively), while the maximum content was observed at 1.25N (0.4% and 2.8%, respectively). Keywords: content; plants

• Nrf2 activation as a future target of therapy for chronic diseases by Taha, Rame; Blaise, Gilbert (2014) - No. 12 (2014): December 2014 / Review Articles Nrf2 activation as a future target of therapy for chronic diseases Authors Rame Taha Department of Anaesthesia, University Montreal, Montreal, Canada Gilbert Blaise Department of Anaesthesia, University Montreal, Montreal, Canada DOI: https://doi.org/10.31989/ffhd.v4i12.160 Abstract Background: Chronic inflammation integrally related to oxidative stress has been increasingly recognized as a contributing factor in various chronic diseases such as neurodegenerative diseases, pulmonary diseases, metabolic syndrome, and cardiovascular diseases as well as premature aging. In this review, we have discussed the role of oxidative stress in various chronic diseases. Keywords: diseases; issn
• Molecular mechanism of intracellular lipid accumulation: Suppressive effect of PycnogenolR in liver cells by Ikuyama, Shoichiro; Fan, Bin; Gu, Jian-Qiu; Mukae, Kumiko; Watanabe, Hideyuki (2013) - Molecular mechanism of intracellular lipid accumulation: Suppressive effect of PycnogenolR in liver cells | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 9 (2013): September 2013 / Review Articles Molecular mechanism of intracellular lipid accumulation: Suppressive effect of PycnogenolR in liver cells Authors Shoichiro Ikuyama Department of Metabolism, Hematology and Rheumatic Diseases (DMHRDs), Kyushu University Beppu Hospital, Beppu 874-0838 Bin Fan Department of Metabolism, Hematology and Rheumatic Diseases (DMHRDs), Kyushu University Beppu Hospital, Beppu 874-0838 Jian-Qiu Gu Department of Metabolism, Hematology and Rheumatic Diseases (DMHRDs), Kyushu University Beppu Hospital, Beppu 874-0838 Kumiko Mukae Department of Metabolism, Hematology and Rheumatic Diseases (DMHRDs), Kyushu University Beppu Hospital, Beppu 874-0838 Hideyuki Watanabe Department of Metabolism, Hematology and Rheumatic Diseases (DMHRDs), Kyushu University Beppu Hospital, Beppu 874-0838 DOI: https://doi.org/10.31989/ffhd.v3i9.40 Abstract Cells are physiologically ready to accumulate lipids such as triacylglycerides in the cytoplasm. Keywords: beppu; diseases; kyushu

• Spirulina, wakame or goji berries do not lower markers of low-grade systemic inflammation in healthy subjects by Driessche, Jose J. van den; Mensink, Ronald P.; Plat, Jogchum (2021) - We have earlier reported that consumption of the algae spirulina (Arthrospira platensis or maxima) and wakame (Undaria pinnatifida) for 17 days, and a single dose of goji berries (Lycium barbarum) did not affect fasting or postprandial CVD risk markers in healthy subjects. No. 12 (2021): December 2021 / Research Articles Spirulina, wakame or goji berries do not lower markers of low-grade systemic inflammation in healthy subjects Authors Jose J. van den Driessche Maastricht University Ronald P. Mensink Maastricht University Jogchum Plat Department Nutrition and Movement Sciences Maastricht University Maastricht, The Netherlands DOI: https://doi.org/10.31989/ffhd.v11i12.853 Abstract Introduction: Keywords: berries; goji; spirulina

• The Effect of Roselle (Hibiscus) Juice on Mood Improvement in Healthy Adults by Almoraie, Noha M.; Aljefree, Najlaa M.; Althaiban, Maha A.; Hanbazaza, Mahitab A.; Wazzan, Huda A.; Shatwan, Israa M (2022) - Drinking hibiscus juice enhanced mood status by increasing relaxation and decreasing fear of the future and heart palpitations in most participants. Conclusion: Drinking hibiscus juice had significant beneficial effects on mood. Keywords: hibiscus; juice; mood

• Bioactive compounds in potatoes: Accumulation under drought stress conditions by B. Wegener, Christina; Jansen, Gisela; Jürgens, Hans-Ulrich (2015) - The plants were grown in pots (from April to September) in a glasshouse with sufficient water supply and under drought stress conditions. Objective: The aim of this study is to determine the effect of drought stress on water, lipid soluble antioxidants, anthocyanins (Ac), soluble phenols, proteins, free AAS, peroxidase (POD) and lipid acyl hydrolase activity (LAH) in tuber tissue. Keywords: drought; research; stress

• Acceptability and tolerability of a Hibiscus sabdariffa L. beverage and effect on biomarkers of pregnant women: Phase I pilot trial by Alcantar-Rodríguez, Victor Eduardo; Osorio-Díaz, Perla; González-Vargas, Edmundo; Puga-Díaz, Ruben; Gutiérrez-Trujillo, Jesús; Saldo-Periago, Jordi (2025) - Participants consumed a daily dose of HS beverage, which provides 9.6 mg of total anthocyanins, and several metabolic parameters were recorded (diastolic and systolic blood pressure, plasma glucose, cholesterol, triglycerides, and creatinine concentrations, as well as urinary protein levels). Conclusion: HS beverage demonstrated acceptability and tolerability. Keywords: beverage; issn; women

• The second-meal effect of Undaria pinnatifida sporophylls (mekabu) in healthy young women: An open-label crossover study by Taga, Masaki; Kazuma Yohizumi; Hitomi Kobayashi; Naoki Iwamoto (2025) - Results: The findings indicated that mekabu consumption at breakfast significantly reduced postprandial blood glucose levels after lunch, compared to the control condition. Objective: This study aimed to investigate whether breakfast consumption of Undaria pinnatifida (mekabu), a seaweed rich in soluble fiber and sulfated polysaccharides, could attenuate postprandial glycemic response at a subsequent meal in healthy young women. Keywords: meal; mekabu

• The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy overweight participants by Azantsa, Boris; Kuate, Dieudonne; Chakokam, Raoul; Paka, Ghislain; Bartholomew, Barbara; Nash, Robert (2015) - The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy overweight participants | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 6 (2015): June 2015 / Research Articles The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy overweight participants Authors Boris Azantsa Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, SW Region, Cameroon;Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Dieudonne Kuate Program in Nutrition, School of Health Sciences Universiti Sains Malaysia, 16150 Kubang Kerian Kelantan, Malaysia; Raoul Chakokam Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Ghislain Paka Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Barbara Bartholomew PhytoQuest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK Robert Nash PhytoQuest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK DOI: https://doi.org/10.31989/ffhd.v5i6.184 Abstract Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Conclusion: The extracts of Irvingia gabonensis and Dichrostachys glomerata, at a dose of 300 mg per day, were effective in reducing weight and positively modifying lipid parameters in healthy overweight participants. Keywords: issn; science; yaounde

• Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages by Etoh, Tadahiro; Kim, Yong P.; Hayashi, Masahiko; Suzawa, Michiko; Li, Shiming; Ho, Chi-Tang; Komiyama, Kanki (2013) - Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 No. 6 (2013): June 2013 / Research Articles Inhibitory effect of a formulated extract from multiple citrus peels on LPS-induced inflammation in RAW 246.7 macrophages Authors Tadahiro Etoh Faculty of Pharmacy, Iwaki Meisei University, Iino, Chuo-dai, Iwaki, Fukushima 970-8551 Yong P. Kim Faculty of Pharmacy, Iwaki Meisei University, Iino, Chuo-dai, Iwaki, Fukushima 970-8551 Masahiko Hayashi Faculty of Pharmacy, Iwaki Meisei University, Iino, Chuo-dai, Iwaki, Fukushima 970-8551 Michiko Suzawa Miyauchi Citrus Research Center, Shigoka-Machi, Takasaki, Gunma, 370-0845 Shiming Li Department of Food Science, Rutgers University, New Brunswick, NJ 08901 Chi-Tang Ho Department of Food Science, Rutgers University, New Brunswick, NJ 08901 Kanki Komiyama Kitasato Research Center for Environmental Sciences, Kitasato, Sagamihara, Kanagawa, 252-0329 DOI: https://doi.org/10.31989/ffhd.v3i6.50 Abstract Background: Formulated Citrus Peel Extract (GL) made from the peels of six citrus fruits available in Japan, namely navel oranges, citrus hassaku, citrus limon, citrus natsudaidai, citrus miyauchi and satsuma, was initially developed as a cosmetic product to protect skin from UV irradiation. Anecdotal evidences of anti-cancer property of GL have been reported by consumers based on the cases such as topical application for melanoma, and oral ingestion for prostate, lung and liver cancers. Keywords: citrus; iwaki

• Characterization and functional properties of new everbearing strawberry (Fragaria x ananasa Duch.) cultivar, ‘Summertiara’ berries by Nagai, Takeshi; Tamai, Misuzu; Sato, Masato; Tanoue, Yasuhiro; Kai, Norihisa; Suzuki, Nobutaka (2014) - Results: The contents of water, proteins, lipids, carbohydrates, and ash were the same as those of other cultivar berries. Methods: Chemical analysis, colour measurement, and sensory evaluation of new everbearing strawberry cultivar, ‘Summertiara’ berries were performed. Keywords: berries; cultivar; summertiara

• Breast cancer prevention with Morinda citrifolia (noni) at the initiation stage by Wang, Mian-Ying; Peng, Lin; Anderson, Gary; Nowicki, Diane (2013) - The number of palpable tumors per group was significantly reduced by 73%, 72% and 80% in 3%, 5%, and 10% TNJ groups respectively when compared with positive controls at the end of 330 days after DMBA administration. When the animals were 55 days old, 25 mg/kg DMBA was fed to the animals in the DMBA group, placebo, and TNJ groups. Keywords: groups; issn; tnj

• Benzotropolone moiety in theaflavins is responsible for inhibiting peptide-transport and activating AMP-activated protein kinase in Caco-2 cells by Park, Ha-Young; Kunitake, Yuri; Matsui, Toshiro (2013) - Expression of PEPT1 protein in Caco-2 cells treated with or without 20 μM TF3’G in the presence or absence of inhibitor (10 μM compound C as AMPK inhibitor or 25 μM STO-609 as CaMKK inhibitor) was evaluated by Western blot. Absorption ability was measured with Caco-2 cell monolayers treated with or without 20 μM sample (TF3’G or its related compounds) in an Ussing Chamber. Keywords: pept1; peptide; transport
• Stability of an anticancer peptide isolated from Flathead by-products during in vitro gastrointestinal digestion by Nurdiani, Rahmi; Vasiljevic, Todor; Singh, Tanoj K; Donkor, Osaana N; Prihanto, Asep A; Kusuma, Titis S (2022) - Nonetheless, one of the most significant challenges in developing fish peptides as functional food ingredients is proving their efficacy as anticancer agents. Keywords: bioactive peptide; digestion; fish by-products; hydrolysis Author Biographies Rahmi Nurdiani, Universitas Brawijaya Department of Fish Product Technology, Faculty of Fisheries and Marine Science, Universitas Brawijaya Todor Vasiljevic, Victoria University Advanced Food Systems Research Unit, College of Health and Biomedicine, Victoria University Tanoj K Singh, CSIRO Keywords: brawijaya; peptide; universitas

• Impact of an extract from the bran layer of rice on the nutrition of lactating mothers and growth of their exclusively breastfed infants: a longitudinal study by Sanchez, Guillermo E.; Sullivan, Glenn H.; Miller, Larry R. (2022) - Infant growth was determined monthly following World Health Organization (WHO) guidelines, including weight-for-length (WHZ), weight-for-age (WAZ), length-for-age (LAZ), BMI-for-age (BAZ) and head circumference-for-age (HCZ). Following a student t-test analysis, infant growth indicators WHZ, WAZ and BAZ showed a highly significant (p<0.01) increase. Keywords: growth; issn; mothers

• Optimization of an effective growth medium for culturing probiotic bacteria for applications in strict vegetarian food products by Pathak, Manju; Martirosyan, Danik (2012) - The possibility of using vegetal protein from TM 2 extract in place of peptones and meat extract for the nitrogen supplementation of culture media for the growth of lactic acid bacteria has been demonstrated.  Methods: Lactobacillus lactis, a probiotic, was grown in standard MRS culture medium as well as in our various test media (TM) containing various vegetal source in place of beef extract, yeast extract and peptone as in case of MRS. Keywords: culture; growth; issn

• Enhancing nutritional care with egg white supplementation on serum albumin level for home-based bed-ridden elderly patients by Detarun, Preeyabhorn; Srichamnanturakit, Vatcharee; Isaramalai, Sang-arun; Rakpanusit, Thaparat (2022) - Enhancing nutritional care with egg white supplementation on serum albumin level for home-based bed-ridden elderly patients | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 6 (2022): June 2022 / Research Articles Enhancing nutritional care with egg white supplementation on serum albumin level for home-based bed-ridden elderly patients Authors Preeyabhorn Detarun Center of Excellence in Functional Food and Gastronomy, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand Vatcharee Srichamnanturakit Center of Excellence in Functional Food and Gastronomy, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand Sang-arun Isaramalai Faculty of Nursing, Prince of Songkla University, Hat Yai Campus, Hat Yai, Songkhla 90110, Thailand Thaparat Rakpanusit Faculty of Nursing, Prince of Songkla University, Pattani Campus, Muang, Pattani 94000, Thailand DOI: https://doi.org/10.31989/ffhd.v12i6.932 Abstract Background: Low serum albumin levels are one of the most common causes of morbidity and mortality in humans, particularly in older bed-ridden patients. Objective: This research aimed to investigate the effects of the egg white formula diet (EWFD) supplement on serum albumin levels in bed-ridden elderly patients with nasogastric tube feeding at home. Keywords: albumin; bed; serum

• Biochemical evaluation of the effects of Nigerian polyherbal preparation on Wistar rabbits by Anugweje, Ken C.; Ojiako, Okey A.; Igwe, Chidi U.; Nwachukwu, Winnifred A.; Ogbuji, Chiza A. (2012) - Biochemical evaluation of the effects of Nigerian polyherbal preparation on Wistar rabbits | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 6 (2012): June 2012 / Research Articles Biochemical evaluation of the effects of Nigerian polyherbal preparation on Wistar rabbits Authors Ken C. Anugweje Dept. of Health Services, University of Port Harcourt, Port Harcourt Okey A. Ojiako Department of Biochemistry, Federal Univ. of Technology, Owerri Chidi U. Igwe Department of Biochemistry, Federal Univ. of Technology, Owerri Winnifred A. Nwachukwu Department of Biochemistry, Federal Univ. of Technology, Owerri Chiza A. Ogbuji Department of Science Lab. Keywords: issn; journal; technology

• Safety of dietary undenatured type II collagen: a pilot open-label overdose clinical investigation by Shiojima, Yoshiaki; Takahashi, Megumi; Takahashi, Ryohei; Moriyama, Hiroyoshi; Maruyama, Kazuo; Bagchi, Debasis; Bagchi, Manashi (2022) - Supplementation of undenatured type II collagen powder (NEXT-II®) in hard capsules has been clinically proven to improve such joint functions fulfilling part of the FFC rigorous guidelines, while ensuring adequate safety as foods is a crucial prerequisite for filing FFC product dossier. Keywords: Undenatured type II collagen, NEXT-II®, Safety, Overdose supplementation, Clinical study, Foods with Function Claims (FFC) Downloads [Abstract] [Full Article] Published 2022-03-04 Issue Vol. 12 No. 3 (2022): March 2022 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Keywords: collagen

• Corozo (Bactris guineensis) fruit extract has antiviral activity in vitro against SARS-CoV-2 by Jaimes-Gualdrón, Tania; Flórez-Álvarez, Lizdany; Zapata-Cardona, María Isabel; Rojano, Benjamín Alberto; Rugeles, María Teresa; Zapata-Builes, Wildeman (2022) - This study aimed to evaluate the in vitro antiviral potential of Corozo fruit extract (Bactris guineensis) against SARS-CoV-2. Conclusion: This is the first report on the in vitro antiviral effect of Corozo fruit extract against SARS-CoV-2. Keywords: colombia; universidad

• Turmeric and Chinese goldthread synergistically inhibit prostate cancer cell proliferation and NF-kB signaling by Zhao, Yi; Collier, J. Jason; Huang, E-Chu; Whelan, Jay (2014) - The synergy of action of combinations of companion bioactives from the same herb (i.e., curcumin/ar-turmerone and berberine/coptisine) and bioactives from different herbs (i.e., curcumin/berberine) help to explain why turmeric and Chinese goldthread are more effective than their major bioactives in isolation. Turmeric and Chinese goldthread synergistically inhibit prostate cancer cell proliferation and NF-kB signaling | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 4 No. 7 (2014): July 2014 / Research Articles Turmeric and Chinese goldthread synergistically inhibit prostate cancer cell proliferation and NF-kB signaling Authors Yi Zhao Department of Nutrition University of Tennessee, Knoxville, TN 37996, J. Jason Collier Department of Nutrition University of Tennessee, Knoxville, TN 37996, E-Chu Huang Department of Nutrition University of Tennessee, Knoxville, TN 37996, Jay Whelan Department of Nutrition, Tennessee Agricultural Experiment Station University of Tennessee, Knoxville, TN 37996, DOI: https://doi.org/10.31989/ffhd.v4i7.1 Abstract Background: Pre-clinical studies using bioactive compounds from botanicals appear to offer some protection against cancer. Keywords: bioactives; issn; tennessee

• Anti-inflammatory effect of Phytomarine R-L compound against lipopolysaccharide- induced pulmonary injury in BALB/c mice by Gopi, Janani; Marotta, Francesco; Sriramulu, Sushmitha; Banerjee, Antara; Kanna, N.R. Rajesh; Palani, Vignesh; Ayala, Antonio; He, Fang; Vijayashree, R; Pathak, Surajit (2022) - Anti-inflammatory effect of Phytomarine R-L compound against lipopolysaccharide- induced pulmonary injury in BALB/c mice | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 11 (2022): November 2022 / Research Articles Anti-inflammatory effect of Phytomarine R-L compound against lipopolysaccharide- induced pulmonary injury in BALB/c mice Authors Janani Gopi Francesco Marotta Sushmitha Sriramulu Antara Banerjee N.R. Rajesh Kanna Vignesh Palani Antonio Ayala Fang He R Vijayashree Surajit Pathak DOI: https://doi.org/10.31989/ffhd.v12i11.1014 Abstract Background: This study deals with the induction of lipopolysaccharide induced inflammation in animal model and treating this condition using phytomarine R-L compound (Bloomin’Age, Science of Living, Milan Italy) that is known to possess the anti-inflammatory properties and eventually determine their characteristics through the in-vivo experimentation. Keywords: compound

• Effectiveness in the short-term of a novel nutraceutical for the management of hypercholesterolemia: an observational multicenter primary care experience by Natale, Francesco; Molinari, Riccardo; Covino, Simona; Piccinocchi, Gaetano; Salvetti, Andrea; Monda, Emanuele; Limongelli, Giuseppe; Cimmino, Giovanni (2022) - In this retrospective analysis, we evaluate the effects of dietary supplementation with a novel monacolin/berberine/bergamot nutraceutical formulation on plasma lipid levels of subjects with low-moderate hypercholesterolemia who are not treated with conventional drug or other dietary supplements.  Effectiveness in the short-term of a novel nutraceutical for the management of hypercholesterolemia: an observational multicenter primary care experience | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 11 (2022): November 2022 / Research Articles Effectiveness in the short-term of a novel nutraceutical for the management of hypercholesterolemia: an observational multicenter primary care experience Authors Francesco Natale Riccardo Molinari Simona Covino Gaetano Piccinocchi Andrea Salvetti Emanuele Monda Giuseppe Limongelli Giovanni Cimmino DOI: https://doi.org/10.31989/ffhd.v12i11.1023 Abstract Purpose: Increasing evidence reinforces the benefits of reduction of low-density lipoprotein (LDL-C) levels on cardiovascular outcomes. Keywords: hypercholesterolemia; issn; journal

• Role of a novel nutraceutical composition for irritable bowel syndrome management: symptoms relief and unexpected triglycerides-lowering effect by Santonicola, Antonella; Molinari, Riccardo; Piccinocchi, Gaetano; Salvetti, Andrea; Natale, Francesco; Cimmino, Giovanni (2023) - Moreover, an unexpected effect of this combination of micronutrients on tryglicerides, beyond IBS symptoms, was also found. Role of a novel nutraceutical composition for irritable bowel syndrome management: symptoms relief and unexpected triglycerides-lowering effect | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 Keywords: ibs; issn; journal

• Chemical, microbial and safety profiling of a standardized Withania somnifera (Ashwagandha) extract and Withaferin A, a potent novel phytotherapeutic of the millennium by Kumar, Pawan; Banik, Samudra P.; Goel, Apurva; Chakraborty, Sanjoy; Bagchi, Manashi; Bagchi, Debasis (2023) - Keywords: Ashwagandha, Withaferin A, phytotherapeutics, material safety; heavy metals; pesticides Downloads Chemical, microbial and safety profiling of a standardized Withania somnifera (Ashwagandha) extract and Withaferin A, a potent novel phytotherapeutic of the millennium | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 Keywords: ashwagandha; issn; journal

• The effects of probiotics in ulcerative colitis patients: a randomized controlled double blind clinical trial by Tamizifar, Babak; Feizi, Awat; Rahim khorasani, Marzieh; Kassaian, Nazila; Zamanimoghadam, Ali; Arbabnia, Shayan; Adibi Sede, Peyman (2023) - The effects of probiotics in ulcerative colitis patients: a randomized controlled double blind clinical trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 11 (2023): November 2023 / Clinical Trial The effects of probiotics in ulcerative colitis patients: a randomized controlled double blind clinical trial Authors Babak Tamizifar Awat Feizi Marzieh Rahim khorasani Nazila Kassaian Ali Zamanimoghadam Shayan Arbabnia Peyman Adibi Sede DOI: https://doi.org/10.31989/ffhd.v13i11.1098 Abstract Background: In the recent decade, ulcerative colitis (UC) as a chronic inflammatory bowel disease has a growing incidence and prevalence in the world. Probiotics might be a promising approach to improve ulcerative colitis by favorably modifying the gut microbiota.   Keywords: colitis; issn

• The effect of polydextrose on fecal bulk and bowel function in mildly constipated healthy adults: a double-blind, placebo controlled study by Risso, Davide; Laurie, Ieva; Sarkkinen, Essi; Karnik, Kavita (2023) - Material and Methods: We investigated the effects of PDX consumption by healthy subjects experiencing one or more symptoms of mild constipation on fecal bulk, defecation frequency, stool consistency, ease of stool passage, and total colonic transit time to further characterize and generate additional evidence regarding the potential beneficial effects of this fibre. The effect of polydextrose on fecal bulk and bowel function in mildly constipated healthy adults: a double-blind, placebo controlled study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 5 (2023): May 2023 / Research Articles The effect of polydextrose on fecal bulk and bowel function in mildly constipated healthy adults: a double-blind, placebo controlled study Authors Davide Risso Ieva Laurie Essi Sarkkinen Kavita Karnik DOI: https://doi.org/10.31989/ffhd.v13i5.1099 Abstract Background: Polydextrose (PDX) (8-30g/day) increases fecal bulk and consistency, helping to ease stool passage. Keywords: issn; pdx

• Marketability level of potato in Armenia: Potato functional properties by Tspnetsyan, Hrachya; Pepoyan, Elya; Pepoyan, Astghik; Abrahamyan, Syuzanna (2023) - Conclusion: The increase in metabolic/non-communicable diseases, increased consumer awareness of these diseases and their prevention, as well as developments in organic agriculture and functional food production require changes in economic research and calculations, also related to functional foods.   What’s also important is the profile of the company's personnel and the work of personnel in the market, advertising related to the quality of the product, which in recent times is especially based on the natural origin and functional value of the product․  Objective: The aim of the current study is to quantify the factors influencing the level of potato marketability through econometric analysis in Armenia. Keywords: level; marketability; potato

• Pharmacokinetic effect of Astragalus membranaceus and Panax notoginseng saponins on arginine absorption and nitric oxide production in healthy subjects by Lin, Ching-Pin; Lin, Chao-Tian; Wu, I-Chin; Pan, Ting-Yn; Shen, You-Cheng (2023) - Pharmacokinetic effect of Astragalus membranaceus and Panax notoginseng saponins on arginine absorption and nitric oxide production in healthy subjects | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 6 (2023): June 2023 / Research Articles Pharmacokinetic effect of Astragalus membranaceus and Panax notoginseng saponins on arginine absorption and nitric oxide production in healthy subjects Authors Ching-Pin Lin Chao-Tian Lin I-Chin Wu Ting-Yn Pan You-Cheng Shen https://orcid.org/0000-0002-3098-4712 DOI: https://doi.org/10.31989/ffhd.v13i6.1104 Therefore, this study aimed to examine whether the standardized intake of Astragalus membranaceus and Panax notoginseng saponins (APS) could increase NO production by enhancing arginine absorption and reducing levels of asymmetric dimethylarginine (AMDA). Keywords: arginine; issn

• Living life the natural way – Wheatgrass and Health by Rana, Satyavati; Kamboj, Jaspreet Kaur; Gandhi, Vandana (2011) - No. 11 (2011): November 2011 / Review Articles Living life the natural way – Wheatgrass and Health Authors Satyavati Rana Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh Jaspreet Kaur Kamboj Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh Vandana Gandhi Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh DOI: https://doi.org/10.31989/ffhd.v1i11.112 Abstract The Human diet is enriched with young parts of plants (so called “green foods”), which can improve nutrient balance intake in natural way. Wheatgrass juice helps in building red blood cells and stimulates healthy tissue cell growth. Keywords: issn; wheatgrass

• Development, quality and safety evaluation of a probiotic whey beverage by Abitayeva, Gulyaim; Bissenova, Gulmira; Mussabayeva, Botagoz; Naimanov, Yerassyl; Тultabayeva, Тamara; Sarmurzina, Zinigul (2023) - Keywords: Whey beverage, Formulation, Probiotic, Functional, Safety Assessment, Toxicity, Allergenic properties, In vivo Author Biographies Gulyaim Abitayeva, Republican Collection of Microorganisms LLP, Astana, Kazakhstan PhD, Leading Researcher  Gulmira Bissenova, Republican Collection of Microorganisms LLP, Astana, Kazakhstan PhD, Researcher Botagoz Mussabayeva, Republican Collection of Microorganisms LLP, Astana, Kazakhstan Ms, Researcher Yerassyl Naimanov, JSC Astana-onim, Astana, Kazakhstan Ms, Technologist Тamara Тultabayeva, NCJSC S. Seifullin Kazakh Agro Technical Research University Astana, Kazakhstan D.Sc., Principal investigator Zinigul Sarmurzina, Republican Collection of Microorganisms LLP, Astana, Kazakhstan PhD, Project manager Downloads No. 7 (2023): July 2023 / Research Articles Development, quality and safety evaluation of a probiotic whey beverage Authors Gulyaim Abitayeva Republican Collection of Microorganisms LLP, Astana, Kazakhstan https://orcid.org/0000-0001-6999-8807 Gulmira Bissenova Republican Collection of Microorganisms LLP, Astana, Kazakhstan Botagoz Mussabayeva Republican Collection of Microorganisms LLP, Astana, Kazakhstan Yerassyl Naimanov JSC Astana-onim, Astana, Kazakhstan Тamara Тultabayeva NCJSC S. Seifullin Kazakh Agro Technical Research University Astana, Kazakhstan Zinigul Sarmurzina Republican Collection of Microorganisms LLP, Astana, Kazakhstan DOI: https://doi.org/10.31989/ffhd.v13i7.1121 Abstract Background: This study was aimed at the development of a whey beverage enriched with a probiotic starter culture, prebiotics, vitamins, and minerals, and evaluation of microbiological, physico-chemical, and toxicological characteristics of the developed beverage. Keywords: astana; kazakhstan; microorganisms

• Evaluation of theobromine content and the relationship between cocoa percentages in dark chocolates by Eren, Fatma Hulyam; Kabaran, Seray (2023) - Results: Overall range for theobromine content varied from 1.9 to 9.6 mg/g. Of all, bittersweet dark chocolate had the highest (8.1±1.01 mg/g) concentration of theobromine in comparison to semisweet dark chocolate (6.4±0.79 mg/g). Objective: The present study aims to analyze the theobromine contents of commercial chocolates and evaluates the association between the labeled cocoa mass percentage (%), theobromine contents and evaluated non-fat cocoa solid (NFCS) parameters of dark chocolates.  Keywords: dark; theobromine

• Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel-group trial by Abe, Aya; Kapoor, Mahendra P.; Morishima, So; Timm, Derek; Nakajima, Atsushi; Ozeki, Makoto; Sato, Norio (2023) - Conclusion: MSE consumption has showed potential in lowering physical discomfort brought on by exhaustion, promoting overall QOL, and improving sleep quality. (UMIN000049070) Keywords:moringa; moringin; glucomoringin; physical discomfort; sleep quality; fatigue; pain Downloads Keywords: discomfort; issn; journal

• Total Dietary Fiber, and Selected Vegetable, Fruit, Legume and Cereal Fiber Intake and Risk of Heart Attack in Periodontitis Subjects by Wood, Nelson (2011) - Results: Individuals with periodontitis, that consumed low levels of the selected vegetables and fruits had a significantly increased risk of self-reported HA for: low total dietary fiber intake levels(P<0.005); low levels of selected vegetables - low broccoli and any other vegetables(P<0.01); Brussels sprouts, carrots, cabbages, spinach and tossed salads(P<0.05), and low selected fruits – citrus fruits, peaches/nectarines and any other fruits(P<0.05), adjusting for confounders of both diseases and energy (Kcal). Adjusting the model further for serum antioxidants, dietary cholesterol and other fat intake maintained a significantly higher HA risk for: low total dietary fiber intake levels(P<0.05); low levels of selected vegetables - low broccoli, spinach(P<0.05) and any other vegetables(P=0.05); but significantly increased HA risk with low all-bran cereal(P<0.05). Keywords: fiber; periodontitis; risk

• The phytochemical study of Eleutherococcus senticosus (Rupr. & Maxim) leaves in hydroponics and soil culture by Vardanyan, Anush; Ghalachyan, Laura; Tadevosyan, Anna; Baghdasaryan, Varduhi; Stepanyan, Anjelika; Daryadar, Mahsa (2023) - According to the results of a phytochemical study of E. senticosus leaves grown in outdoor hydroponics and soil culture in the Ararat Valley, the highest content of biologically active compounds (eleutherosides, phenols, phenolic acids, vitamins) is recorded in hydroponic plants in the flowering period. All parts of E. senticosus: roots, stems, leaves, and berries, have medicinal properties. Keywords: content; senticosus

• Juice yield and pectin indicators in apple and carrot pomace by Al-Yasari, Arkan; Barakova, Nadezhda; Alkhateeb, Reem; Hovhannisyan, Filipp; Baskovtcev, Angelina; Kiprushkina, Elena (2023) - Results: The results of our experiments revealed that for apple pomace processing, it is more beneficial to use the enzyme preparation Vegazym M with a dosage of 0.09% of the pomace mass, while for carrot pomace processing, the enzyme preparation Fructozym MA with a dosage of 0.07% of the pomace mass proved to be the most suitable. Our objectives were to select an enzymatic preparation for processing apple and carrot pomace and to study changes in the properties of pectins present in the pomace depending on the dosage of the enzyme preparation. Keywords: pectin; pomace

• The effect of phenolic compounds contained in flour from green buckwheat, flaxseed, grape and dogwood seeds on the fermentation activity of yeast S. cerevisiae by Grinvald, Svetlana A.; Barakova, Nadezhda; Kiprushkina, Elena; Jamaldinova, Birlant; Ushaeva, Irina; Tochilnikov, Grigory; Sadovoy, Vladimir; Gunkova, Polina (2024) - Keywords: dogwood seed flour, grape seed flour, green buckwheat flour, flaxseed flour, yeast fermentation activity, phenolic compounds Downloads [Abstract] [Full Article] Published 2024-03-29 Issue Vol. 14 The effect of phenolic compounds contained in flour from green buckwheat, flaxseed, grape and dogwood seeds on the fermentation activity of yeast S. cerevisiae | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 3 (2024): March 2024 / Research Articles The effect of phenolic compounds contained in flour from green buckwheat, flaxseed, grape and dogwood seeds on the fermentation activity of yeast S. cerevisiae Authors Svetlana A. Grinvald Nadezhda Barakova Elena Kiprushkina Birlant Jamaldinova Irina Ushaeva Grigory Tochilnikov Vladimir Sadovoy Polina Gunkova DOI: https://doi.org/10.31989/ffhd.v14i3.1191 Abstract Background: Bakery products are one of the most widely consumed in the world, but they have very low nutritional value and a short shelf life. Keywords: flour; phenolic; seeds

• Developing an Effective Food Supplement for the Prevention of Osteoporosis by Leung, Ping-chung; Ko, Erik Chun-hay; Siu, Sammy Wing-sum; Pang, Ellie Suet-yee; Cheng, King-fai; Chan, Yat-heung (2011) - Therefore it becomes clear now that prevention of bone mineral loss through a natural maintenance process will be more beneficial for those not under special risks. In the past twenty years, many pharmaceuticals are created to prevent bone loss. Keywords: hong; kong; university

• Safety evaluation of high bioavailability curcumin in Healthy Japanese Adults: A Randomized, placebo-controlled, double-blind, parallel-group comparison study by Lee, Hyunjin; Kuwabara, Yoshitaka; Hirose, Akiko; Kakinuma, Toshihiro; Baba, Asami; Takara, Tsuyoshi (2023) - Safety evaluation of high bioavailability curcumin in Healthy Japanese Adults: A Randomized, placebo-controlled, double-blind, parallel-group comparison study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 13 No. 12 (2023): December 2023 / Research Articles Safety evaluation of high bioavailability curcumin in Healthy Japanese Adults: A Randomized, placebo-controlled, double-blind, parallel-group comparison study Authors Hyunjin Lee Theravalues Corporation Yoshitaka Kuwabara Akiko Hirose Toshihiro Kakinuma Asami Baba Tsuyoshi Takara DOI: https://doi.org/10.31989/ffhd.v13i12.1207 Abstract Background:  Curcumin is the principal component responsible for the pharmacological action of Curcuma longa. Keywords: safety; trial

• Effect of dietary fiber-enriched brown rice crackers on suppressing elevation of blood glucose level by Suzuki, Hiroshi; Watanabe, Kenichi; Ikeda, Izumi; Takeda, Yasunaga; Hatta, Mariko; Horikawa, Chika; D’Avila Ferreira, Efrem; Sijia, Wu; Laymon, Khin; Sone, Hirohito (2023) - Incremental area under curves at 60 min and 120 min after intake of rice crackers were also significantly lower in dietary fiber-enhanced brown rice crackers than white rice crackers. Keywords: Brown rice crackers, Dietary fiber, Postprandial blood glucose Downloads [Abstract] [Full Article] Published 2023-11-14 Issue Vol. 13 No. 11 (2023): November 2023 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Keywords: graduate school; metabolism; university graduate

• Using Food Grade Lye “omushelekha” in the Formulation of Health Products from Commonly Consumed African Indigenous Vegetables and Vegetable Combinations by Walingo, Mary K.; Habwe, Florence O. (2011) - Iron content was high in the Solanum scabrum (281.1mg/100g), and Crotolaria occloreuca (110/100g), Amaranthus blitum (108mg/100g) boiled-fried with lye. This could be attributed different nutrient-nutrient interactions between different vegetables combinations. Keywords: boiled; copper; lye

• Clinical effect of phytosterol-enriched saw palmetto extract on urinary function in healthy middle-aged and older males: a double-blind, placebo-controlled randomized comparative study by Hisajima, Tatsuya; Waki, Hideaki; Suzuki, Takuya; Izumi, Takashi (2024) - Keywords: saw palmetto, VISPO™, β-sitosterol, fatty acids, healthy subjects, primary preventive, IPSS, OABSS, lower urinary tract symptoms (LUTS) Downloads β-sitosterol-enriched saw palmetto oil (VISPO™) contains more than 3% β-sitosterol and 85% total fatty acids and has been shown to improve symptoms in patients with BPH. Keywords: issn; vispo

• In vitro propagation of stone fruit rootstock cultivar Evrica 99 and its influence on some phytochemical traits of fresh apricot fruit by Melyan, Gayane; Santrosyan, Gagik (2024) - No. 2 (2024): February 2024 / Research Articles In vitro propagation of stone fruit rootstock cultivar Evrica 99 and its influence on some phytochemical traits of fresh apricot fruit Authors Gayane Melyan Gagik Santrosyan DOI: https://doi.org/10.31989/ffhd.v14i2.1317 Abstract Background: The cultivation of stone fruits is of primary importance in Armenia. In vitro propagation of stone fruit rootstock cultivar Evrica 99 and its influence on some phytochemical traits of fresh apricot fruit | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 Keywords: fruit; rootstock

• The beneficial effects of monoglucosyl hesperidin and monoglucosyl rutin on vascular flexibility: a randomized, placebo-controlled, double-blind, parallel-group study by Hashizume, Yushi; Tandia, Mahamadou (2024) - The beneficial effects of monoglucosyl hesperidin and monoglucosyl rutin on vascular flexibility: a randomized, placebo-controlled, double-blind, parallel-group study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 5 (2024): May 2024 / Research Articles The beneficial effects of monoglucosyl hesperidin and monoglucosyl rutin on vascular flexibility: a randomized, placebo-controlled, double-blind, parallel-group study Authors Yushi Hashizume Mahamadou Tandia DOI: https://doi.org/10.31989/ffhd.v14i5.1319 Abstract Background: There is mounting evidence that the intake of polyphenols can help prevent cardiovascular complications. Objective: The present study aimed to evaluate the efficacy of daily intake of 70 mg of monoglucosyl hesperidin (MH) alone, or in combination with 140 mg of monoglucosyl rutin (MR), in improving vascular flexibility. Keywords: flexibility; monoglucosyl

• Exploring the potential of pomegranate (Punica granatum) peel extract and punicalagin as novel anti-hypercholesterolemic agents by Dehghani, Parva; Masjedi, Motahareh; Shariati, Laleh; Vaseghi, Golnaz; Dana, Nasim; Zeinalian, Mehrdad; Asgary, Sedigheh (2024) - Conclusion: These findings suggest that pomegranate peel extract and punicalagin have the potential to serve as effective agents in managing hypercholesterolemia by enhancing LDL receptor expression and reducing PCSK9 expression in HepG2 cells. Objective: This study investigates the potential of pomegranate peel extract and punicalagin, a key pomegranate component, in lowering LDL cholesterol in HepG2 cells. Keywords: ldl; pomegranate; punicalagin

• The modulatory effect of Al-Assi river trout fish meal on OCD manifestations and molecular mechanisms in BALB/c Mice by Salloum, Fatima; Farran, Mohamad; Shaib, Houssam ; Jurjus, Abdo; Sleiman, Roni; Khalil, Mahmoud (2024) - Methods: OCD mice were divided into five groups: one control group without any treatment, one group treated with fluoxetine (a selective serotonin reuptake inhibitor), and three groups fed with different doses of trout fish meal (0, 7.5, and 15 g/kg body weight). For instance, in the marble test, OCD mice fed with 7.5 g of trout fish/kg body weight buried more marbles than those fed with 15 g/kg of trout fish (4.5 vs 3.33 out of 6, p>0.05). Keywords: fish; ocd; trout

• Restorative effect of bean ferritin iron on low hemoglobin level in premenopausal women with menstruation-induced anemia: A randomized, double-blind placebo-controlled intergroup trial by Takeda, Ryuji; Kuriyama, Yuji; Yoshida, Yasushi (2024) - Restorative effect of bean ferritin iron on low hemoglobin level in premenopausal women with menstruation-induced anemia: A randomized, double-blind placebo-controlled intergroup trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 14 No. 3 (2024): March 2024 / Research Articles Restorative effect of bean ferritin iron on low hemoglobin level in premenopausal women with menstruation-induced anemia: Keywords: ferritin; hemoglobin

• Effects of Lacticaseibacillus paracasei 327 intake on the intestinal environment in healthy adult Japanese: a randomized, double-blind, placebo-controlled, parallel-group trial by Senda-Sugimoto, Yoshie; Mihara, Toshihiro; Higuchi, Yuki; Uchiyama, Kimiko; Takara, Tsuyoshi; Takahashi, Hajime (2024) - No. 3 (2024): March 2024 / Research Articles Effects of Lacticaseibacillus paracasei 327 intake on the intestinal environment in healthy adult Japanese: a randomized, double-blind, placebo-controlled, parallel-group trial Authors Yoshie Senda-Sugimoto Toshihiro Mihara Yuki Higuchi Kimiko Uchiyama Tsuyoshi Takara Hajime Takahashi DOI: https://doi.org/10.31989/ffhd.v14i3.1336 Abstract Background: Lacticaseibacillus paracasei 327 (L. paracasei 327) is a lactic acid bacteria isolated from brown rice. Given the reported relationship between intestinal microbiota and bowel movement, we hypothesized that L. paracasei 327 also improves the intestinal environment through its involvement in fluctuations in the composition of the intestinal microbiota. Keywords: environment; paracasei

• Lactic acid-fermented Sake lees protect against nonalcoholic steatohepatitis in mice by Suzuki, Hiroshi; Watanabe, Kenichi; Arumugam, Somasundaram; Afrin, Rejina; Yamamoto, Masahiko; Matsubayashi, Yasuhiro; Sone, Hirohito (2024) - Objectives: The objectives of this study are to evaluate the hepatoprotective effects of lactic acid-fermented sake lees (FSL) in a mouse model of NASH-HCC, to assess the impact of FSL supplementation on blood glucose levels in mice with NASH, to analyze the expression of inflammatory markers in FSL-fed mice compared to controls, and to determine the overall efficacy of FSL in inhibiting the progression of NASH. Lactic acid-fermented sake lees (FSL) are a food produced by lactic acid fermentation and dealcoholization of sake lees. Keywords: fsl; sake

• Efficacy and selenium enrichment of Lycium barbarum in hydroponic and soil conditions in the Ararat valley by Babakhanyan, Michael; Ghalachyan, Laura; Chavushyan, Vergine; Simonyan, Karen; Darbinyan, Lilit; Gulnazaryan, Shushanik; Hovhannisyan, Lusya (2024) - The research focuses on the impact of adding exogenous Se on plant productivity,  Se accumulation, and the content of biologically active substances (BAS) in Lb berries and leaves.  Objective: This study investigates Se enrichment of Lycium barbarum (Lb) and its effectiveness in hydroponic and soil conditions in the Ararat Valley. Keywords: hydroponic

• Weight in relation to feeding practice among two years old children in Al-Hillah City by Talib Abed, Mohammed; Mohammed Kassim, Nuhad ; Nidhal Sajjad, Lina (2024) - Results: The study indicated that (76.7%) of mothers have bad feeding practices regarding child feeding, whereas (23.3%) have good feeding practices. There was a significant correlation between the type of feeding and infant weight and a strong association between the mother’s feeding practice and child weight. Keywords: feeding; issn

• Optimization of ultrasound-assisted extraction using box-Behnken design, method validation, and analysis of phytochemicals from drying treatments in the application of Etlingera elatior inflorescence by Firdhauzi, Amila ; Takahashi Yupanqui, Chutha ; Setyaningsih, Widiastuti ; Vatcharee (2024) - Results: The suggested condition of optimized UAE extraction was 70% ethanol, Keywords: Box-Behnken Design, drying treatment, tea, method validation, phenolic. Keywords: drying; uae

• In vitro antioxidant and alpha-glucosidase inhibitory activities of coriander (Coriandrum sativum L.) root extracts by Choochuntra, Lanlita; Nutmakul, Thanutchaporn; Chewchinda, Savita; Sirivarasai, Jintana; Chunhabundit, Rodjana (2024) - Objective: This research delved into the antioxidative capabilities and alpha-glucosidase inhibitory properties of coriander root extracts and assessed their phytochemical makeup.  Conclusion: Coriander roots, a common culinary ingredient, exhibited antioxidant and alpha-glucosidase inhibitory activities, suggesting potential as a functional food for preventing age- and lifestyle-related diseases, such as diabetes and certain cancers. Keywords: coriander; glucosidase

• Potential of Pandan anggur (Sararanga Sinuosa Hemsley) as immunomodulator by Lefaan, Paula; Muediati, Agnes; Fibri, Dwi Larasatie Nur; Nurliyani (2024) - No. 7 (2024): July 2024 / Research Articles Potential of Pandan anggur (Sararanga Sinuosa Hemsley) as immunomodulator Authors Paula Lefaan Agnes Murdiati Dwi Larasatie Nur Fibr Nurliyani DOI: https://doi.org/10.31989/ffhd.v14i7.1378 Abstract Background: Pandan Anggur plant is an endemic plant of the Papua archipelago in Indonesia, and the fruit called Pandan Anggur Fruit (PAF) is freshly consumed or prepared as a juice. The treatment lasted for seven weeks in total and the measurement of immunomodulator parameters was carried out at the end of the treatment period. Keywords: anggur; issn; paf

• Effects of black vinegar, Kurozu, on chromatin modifications and microRNA expression in the mouse liver by Shibayama, Yoshihiko; Fujii, Akira; Fujimoto, Yuki; Hamada, Kensaku (2024) - Conclusion: These results suggested that HFD affects miR expression levels by changing chromatin modification levels and that supplementation with CK suppressed HFD-induced increases in H3K4me2 levels. Kurozu has also been suggested to confer health benefits by altering gene expression; however, the molecular basis is not yet understood. Keywords: expression; hfd; issn

• Synergistic effect of partially hydrolyzed guar gum on Clostridium butyricum in a synbiotic combination for enhanced butyrate production during in-vitro fermentation by Matsumiya, Yoshiki ; Kapoor, Mahendra P; Yamaguchi, Akiko ; Abe, Aya ; Sato, Norio (2024) - Objective: The synergistic effects of commercially available prebiotic partially hydrolyzed guar gum (PHGG) dietary fiber as a carbon source on a butyrate-producing bacterial strain were evaluated during in-vitro fermentation with Clostridium butyricum bacterial strain in a basal medium. Methods: The examined functional dietary fiber substrates (PHGG, LMW-PHGG, indigestible dextrin, and inulin) demonstrated selective prebiotic effects on pH variation of a basal medium, leading to enhanced bacterial growth and butyrate production with Clostridium butyricum bacterial strains during in-vitro fermentation.  Keywords: butyricum; clostridium

• Red Panax ginseng root promotes neuronal plasticity in vitro and improves cognitive function in aged animals by Lelong, Camille; Mandoux, Antoine; Houyoux, Nicolas; Defrere, Sylvie; Mariage, Pierre-Antoine (2024) - Altogether, these results indicate that red Panax ginseng root promotes neuronal plasticity and synaptogenesis in in vitro models and improves short-term memory deficits in in vivo models of aging.  In aging mice, oral administration of red Panax ginseng root powder for 7 days significantly improved short-term memory deficit associated with aging. Keywords: ginseng; panax

• A Clinician’s Perspective on Incorporating Therapeutic Lifestyle Change into Clinical Practice by McIntosh, Mark S. (2011) - Key words: therapeutic lifestyle change, lifestyle counselor, lifestyle medicine, metabolic syndrome, dietary modification Downloads [Abstract] [Full Article] Published 2011-02-16 Issue Vol. 1 No. 2 (2011): February 2011 / Review Articles A Clinician’s Perspective on Incorporating Therapeutic Lifestyle Change into Clinical Practice Authors Mark S. McIntosh University of Florida College of Medicine, Jacksonville, FL 32209 DOI: https://doi.org/10.31989/ffhd.v1i2.140 Abstract This article describes the unique perspective of a clinician who was originally trained as an acute care specialist but in recent years had the opportunity to witness the positive impact of therapeutic lifestyle change (TLC) programs in managing chronic diseases. Keywords: issn; lifestyle

• Antiviral activity of Nigella sativa oil against two SARS-CoV-2surrogates in vitro as a dietary product by Jiang, Xiuping; Huang, Jinge; Wang, Jingxue (2024) - Our results also suggest that HCoV OC43 may be a more appropriate surrogate for SARS-CoV-2 to screen antiviral dietary products. Antiviral activity of Nigella sativa oil against two SARS-CoV-2surrogates in vitro as a dietary product | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: bso; sars

• Biologically active compounds from edible mushroom: Effect on HeLa cells by Avagyan, Inesa; Minasbekyan, Liya; Nanagulyan, Siranush (2024) - Results: Extracts of P. ostreatus mycelial culture significantly suppressed the growth of proliferative activity of human tumor cultures and completely suppressed the mitotic activity of continuous HeLa cell cultures to 72 hours. Our study revealed a significant increase in glutamic and aspartic acids in mycelial culture extracts treated by mm-waves. Keywords: hela; issn

• Effect of the culture liquid of Antarctic yeast Nadsoniella nigra on rooting, growth, and biochemical composition of in vitro grapevine (Vitis vinifera L.), cultivar 'Karmrahyut' by Melyan, Gayane; Sahakyan, Aghvan; Barseghyan, Andranik; Dangyan, Kima; Sahakyan, Narek ; Zadayan, Meruzhan; Martirosyan, Yuri (2024) - Chlorophyll content was higher in Nn culture liquid treated microcuttings, with a maximum total chlorophyll of 2.20 mg/g at 2.0 mg/L, compared to a peak of 2.05 mg/g in IBA-treated microcuttings at 1.0 mg/L. Sugar and vitamin C content increased with Nn culture liquid concentrations, whereas IBA showed a less consistent effect. Nn culture liquid was an effective natural alternative to IBA for promoting rooting in grapevine microcuttings. Keywords: grapevine; liquid; rooting

• Probiotic yeast Saccharomyces cerevisiae var. boulardii: properties and peculiarities of use in functional foods development by Manshin, Dmitrii; Kuntsova, Maria; Shilenko, Alexey; Andreeva, Anastasia (2025) - boulardii: properties and peculiarities of use in functional foods development Authors Dmitrii Manshin Maria Kuntsova Alexey Shilenko Anastasia Andreeva DOI: https://doi.org/10.31989/ffhd.v15i5.1482 Abstract The unconscious human consumption of probiotic microorganisms due to fermented foods in the daily diet has lasted for many centuries. boulardii, probiotics, functional food, fermented foods, yeast Downloads [Abstract] [Full Article] Published 2025-05-23 Issue Vol. 15 Keywords: cerevisiae; var

• Elemental analysis and ecological safety assessment of nutritive herb Ziziphora clinopodioides Lam. cultivated and wild growing in the South-Caucasian flora by Ulikhanyan, Greta; Hovhannisyan, Vahe; Arshakyan, Naira; Altunyan, Astghik; Ghukasyan, Nelli; Ghazaryan, Arshaluys; Dumanyan, Karine; Poghosyan, Gayane; Hovhannisyan, Hrachya; Danielyan, Lusine; Harutyunyan, Ruzanna; Feschyan, Sona; Hovsepyan, Maya; Mkrtchyan, Siranush; Kyslychenko, Viktoria; Chichoyan, Naira (2024) - Furthermore, hierarchical cluster analysis (HCA) enabled the categorization of plant raw material samples into three distinct groups, contingent on the geographical origins of the areas and the methods of cultivation. Conclusions: Chemometric analysis conclusively demonstrates that the variation in elemental composition within the examined samples, as well as the plant's capacity to accumulate biologically active compounds, is contingent not solely upon the altitude of the growth locations above sea level but also by the conditions of cultivation and introduction. Keywords: analysis; clinopodioides; journal

• Investigating the efficacy of 18-week salmon protein hydrolysate supplementation on metabolic inflammation, well-being, and cosmetic outcomes: A pilot clinical trial in healthy adults by Christian Bjerknes; Nicholas Framptom; Crawford Currie (2024) - Objective: The primary objective of this proof-of-concept clinical trial was to evaluate the effects of daily low-dose SPH supplementation on energy levels, oxidative stress, inflammation, and cosmetic outcomes in healthy adults, with a focus on potential gender-specific effects. Notably, women experienced greater improvements in both energy levels and cosmetic outcomes, suggesting SPH may be a beneficial supplement for enhancing overall well-being and cosmetic health, particularly among women. Keywords: issn; outcomes

• A clinical investigation to determine the safety and efficacy of a novel, patented prunus domestica extract in benign prostatic hyperplasia (BPH) by Sankhwar, S.N.; Verma, Narsingh; Patel, Naresh; Kumar, Pawan; Goel, Apurva; Rungta, Mehul (2025) - In contrast, conventional drugs are based on alpha-adrenergic receptor antagonists or Type 2 5-alpha reductase inhibitors; phototherapeutics —especially phytosterols from the plum family, Prunus domestica and Prunus africana—have shown promise in BPH treatment by lowering prolactin and cholesterol levels in the prostate. Objectives: This research aimed to conduct a robust clinical trial to evaluate the effects of Prosman™, a novel patented and standardized extract of Prunus domestica, in patients aged 40–65 suffering from BPH. Keywords: bph; domestica; prunus

• Urolithin A represses IgE-induced degranulation in RBL-2H3 cells by Hirate, Daiya; Higa, Miwa; Masuda, Yutaka; Takada, Kimihiko (2025) - However, the effect of urolithins on mast cell degranulation has not been reported. Novelty of the Study: This study is the first to report the effect of UA on mast cell degranulation. Keywords: degranulation

• Gum Acacia supplementation improves adiponectin levels and HbA1c/adiponectin ratio in women with type 2 diabetes: A randomized controlled trial by Babiker, Rasha; Ali , Ibrahim Abdelrhim ; Merghani , Tarig H. ; Banaga , Amin SI ; Hashim , Nada Tawfig ; Ahmed , Mohammed Seed ; Saeed , Amal M. (2025) - This study aimed to test the effects of oral GA consumption on serum adiponectin levels, glycemic parameters, and the glycosylated hemoglobin/adiponectin ratio in diabetic women. This study uniquely explores the impact of Gum Acacia (GA) on serum adiponectin levels and the HbA1c/adiponectin ratio in type 2 diabetic women. Keywords: adiponectin; hba1c; ratio

• The efficacy of an edible bird's nest in the restoration and enhancement of kidney glomeruli and peritubular capillaries in induced diabetic rats by increasing TGF-β and CD 31 by Komolkriengkrai, Manaras; Matsathit, Udomlak; Jangchart, Rawipa; Sirinupong, Nualpun; Radenahmad, Nisaudah; Khimmaktong, Wipapan (2025) - The efficacy of an edible bird's nest in the restoration and enhancement of kidney glomeruli and peritubular capillaries in induced diabetic rats by increasing TGF-β and CD 31 | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 5 (2025): May 2025 / Research Articles The efficacy of an edible bird's nest in the restoration and enhancement of kidney glomeruli and peritubular capillaries in induced diabetic rats by increasing TGF-β and CD 31 Authors Manaras Komolkriengkrai Udomlak Matsathit Rawipa Jangchart Nualpun Sirinupong Nisaudah Radenahmad Wipapan Khimmaktong DOI: https://doi.org/10.31989/ffhd.v15i5.1591 Abstract Background: Diabetic nephropathy (DN) is primarily caused by hyperglycemia-induced angiogenesis and fibrosis. This research investigated the impact of EDB on diabetic nephropathy of glomeruli and peritubular capillaries in induced diabetic rat models. Keywords: capillaries; edb; issn

• Bovine colostrum antibodies against human viral antigens by Shlykova, Darya; Yurkova, Maria; Burachevskii, Nikolay; Mayzel, Sergey; Fedorov, Alexey (2025) - BC significantly contributes to human nutrition and health, as its effectiveness against certain human viruses is well-studied. Methods: The study's goal was to determine whether BC fractions from cows contain antibodies with cross-reactivity against recombinant human proteins represented by receptor-binding domain (RBD) and nucleocapsid (NP) proteins of various strains of human SARS-CoV-2 coronavirus, including the Wuhan, Lambda, Mu, and Omicron variants. Keywords: antibodies; bovine

• Safety and efficacy study of Lutein (VitaLutein®) in healthy Japanese adults: A randomized, placebo-controlled, double-blind, parallel-group comparative study by Lee, Hyunjin; Itano, Takayuki; Mohamed, Faizal ; Suzuki, Naoko ; Takara, Tsuyoshi ; Yamada , Takahiro (2025) - Thirty-one healthy Japanese adults were randomized to either the placebo or VitaLutein® group. Conclusions: These results suggest that continuous ingestion of VitaLutein® supplements may reduce oxidative stress and maintain macular pigment. Keywords: vitalutein

• Regetting-18 complex powder (R-18CP) - A formulation of components from food-medicine and its anti-aging effects by Davis, Paul; Yuan, Lan (2025) - Novelty of the Study: This study is the first to report that an R-18CP can exert anti-aging effects through telomere protection and improved mitochondrial function in zebrafish models. Regetting-18 complex powder (R-18CP) - A formulation of components from food-medicine and its anti-aging effects | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 7 (2025): July 2025 / Research Articles Regetting-18 complex powder (R-18CP) - Keywords: aging; r-18cp

• The journey of Ayurvedic medicines to nutraceuticals by Kaur, Mehakpreet; Chakraborty, Tandra (2025) - The journey of Ayurvedic medicines to nutraceuticals | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 7 (2025): July 2025 / Review Articles The journey of Ayurvedic medicines to nutraceuticals Authors Mehakpreet Kaur Tandra Chakraborty DOI: https://doi.org/10.31989/ffhd.v15i7.1656 Abstract This review examines the historical evolution of the ancient Indian medical system, Ayurveda, through its precolonial, colonial, and postcolonial eras, along with its transformation into the modern framework of nutraceuticals. Nutraceuticals are  bioactive compounds derived from foods and herbs that provide health benefits by acting as preventive or therapeutic agents in managing chronic diseases, including cardiovascular disorders, neurodegenerative conditions, and cancer. Keywords: issn; nutraceuticals

• Effects of dihydrocapsiate on salivary secretion in healthy subjects: A randomized, double-blind, placebo-controlled, crossover study by Yoshida, Keisuke; Takeda, Ryuji; Sakai, Osamu (2025) - Results: DHC intake significantly increased salivary secretion relative to the placebo group (p < 0.05). Effects of dihydrocapsiate on salivary secretion in healthy subjects: A randomized, double-blind, placebo-controlled, crossover study | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 6 (2025): June 2025 / Research Articles Effects of dihydrocapsiate on salivary secretion in healthy subjects: A randomized, double-blind, placebo-controlled, crossover study Authors Keisuke Yoshida Ryuji Takeda Osamu Sakai DOI: https://doi.org/10.31989/ffhd.v15i6.1657 Abstract Purpose: We aimed to assess the effects of dihydrocapsiate (DHC), a non-pungent capsaicin analog, on salivary secretion in individuals experiencing mild dry mouth symptoms. Keywords: dhc; secretion

• Rice-derived glucosylceramides up-regulate HLA-DR expression on myeloid dendritic cells to activate innate immune responses in healthy Japanese subjects: A randomized, placebo-controlled, double-blind trial by Miyasaka, Kenchi; Takeda, Shogo; Yoneda, Akari; Kubo, Mizuki; Shimoda, Hiroshi (2025) - Rice-derived glucosylceramides up-regulate HLA-DR expression on myeloid dendritic cells to activate innate immune responses in healthy Japanese subjects: A randomized, placebo-controlled, double-blind trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 8 (2025): August 2025 / Research Articles Rice-derived glucosylceramides up-regulate HLA-DR expression on myeloid dendritic cells to activate innate immune responses in healthy Japanese subjects: A randomized, placebo-controlled, double-blind trial Authors Kenchi Miyasaka Shogo Takeda Akari Yoneda Mizuki Kubo Hiroshi Shimoda DOI: https://doi.org/10.31989/ffhd.v15i8.1666 Abstract Introduction: In a prior study, we found that rice-derived glucosylceramides (GlCer) improved overall health and alleviated common cold symptoms, including nasal congestion, sore throat, coughing, headache, muscle pain, and diarrhea. Trial Registration: UMIN-CTR: UMIN000055299 Keywords: rice; glucosylceramide; HLA-DR; dendritic cells; CD86 Downloads Keywords: hla; issn

• The influence of 2'-fucosyllactose on intestinal cell function: A comprehensive review of experimental studies by Sulistijono, Eko; Enggar Fitri, Loeki ; Subandiyah, Krisni; Khotimah, Husnul (2025) - This systematic review aims to analyze various experimental studies related to the administration of 2’-Fucosyllactose (2'FL) that have the potential to induce improvement and therapy in NEC cases through intestinal cell function. The influence of 2'-fucosyllactose on intestinal cell function: A comprehensive review of experimental studies | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 10 (2025): October 2025 / Review Articles The influence of 2'-fucosyllactose on intestinal cell function: A comprehensive review of experimental studies Authors Eko Sulistijono Loeki Enggar Fitri Krisni Subandiyah Husnul Khotimah DOI: https://doi.org/10.31989/ffhd.v15i10.1675 Abstract Necrotizing enterocolitis (NEC) is one of the most common gastrointestinal illnesses that causes preterm neonates to die. Keywords: issn; review

• Clinical assessment of CL22209, a standardized proprietary extract of Asparagus racemosus, for mitigating vasomotor and menstrual symptoms in perimenopausal women:  A randomized, double-blind, placebo-controlled study by Yadav , Poonam ; Yadav , Suman; Vedururu, Sai Sarada ; Kiumari, Gayatri (2025) - Precisely, it assessed the extract’s ability to alleviate vasomotor symptoms, menstrual discomfort, and hormonal dysregulation through a comprehensive evaluation of symptom scores, reproductive hormone levels, ovarian follicle counts, and patient-reported outcomes, and ensuring its safety and tolerability over a 120-day supplementation. Clinical assessment of CL22209, a standardized proprietary extract of Asparagus racemosus , for mitigating vasomotor and menstrual symptoms in perimenopausal women:  Keywords: cl22209; issn; symptoms

• Development of a waste-free technology for comprehensive processing of Cornus mas (dogwood) fruits: Production of natural viscous extract and medical suppositories with potential anti-hemorrhoidal activity by Dadayan, Slavik; Poghosyan, Artavazd; Arstamyan, Lilit; Chakhoyan, Ani; Mkrtchyan, Gohar; Hovhannisyan, Anahit; Hovhannisyan, Narine; Dadayan, Ani (2025) - Development of a waste-free technology for comprehensive processing of Cornus mas (dogwood) fruits: Production of natural viscous extract and medical suppositories with potential anti-hemorrhoidal activity | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Development of a waste-free technology for comprehensive processing of Cornus mas (dogwood) fruits: Production of natural viscous extract and medical suppositories with potential anti-hemorrhoidal activity Authors Slavik Dadayan Artavazd Poghosyan Lilit Arstamyan Ani Chakhoyan Gohar Mkrtchyan Anahit Hovhannisyan Narine Hovhannisyan Ani Dadayan DOI: https://doi.org/10.31989/ffhd.v15i9.1726 Abstract Background: Cornus mas (dogwood) is well known for its anti-inflammatory and analgesic properties, making it a promising candidate for hemorrhoid treatment. Results: A waste-free technology for complex utilization of dogwood fruits has been formulated, allowing the production of natural dogwood viscous extract, as well as mixtures of anthocyanins and fatty acids from primary production meals (pits and peel of pulp). Keywords: dogwood; issn; production

• Isolation and identification of the active compounds found in aromatic oils extracted from Mentha longifolia and their use in the extension shelf life of frozen beef patties by Hussien, Sari; Hussein, Suhair; Ismael, Firas; Khashan, Bilal (2025) - Isolation and identification of the active compounds found in aromatic oils extracted from Mentha longifolia and their use in the extension shelf life of frozen beef patties | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Isolation and identification of the active compounds found in aromatic oils extracted from Mentha longifolia and their use in the extension shelf life of frozen beef patties Authors Sari Ali Hussien Suhair Ali Hussein Firas Najm Ismael Bilal Materials and Methods: Our main goal was to use Mentha longifolia, extracted from the Stachys plant using a Clevenger apparatus, and a standardized burger mix was prepared from it. Keywords: issn; longifolia; mentha

• Evaluation and comparative studies of the dissolution profiles of gummi armeniacae and PVP-containing Acetaminophen tablets by Pstikyan, Lianna; Yenokyan, Bagrat; Ghazaryan, Hovhannes; Sargsyan, Felanna; Ghazaryan, Ani; Zhamharyan, Arusyak (2025) - Conclusions: Tablets containing Gummi Armeniacae as a binder possess pH-dependent drug substance release from tablets. Keywords: Gummi Armeniacae, Acetaminophen tablets, Binder, Dissolution profile, PVP Downloads Keywords: armeniacae; gummi; tablets

• Integrative effects of an oral supplement mixture containing melon, yeast extract, and licorice on skin pigmentation reduction: Insights from a zebrafish model and a randomized double-blind controlled pilot human trial by Zheng, Jiani; Sun, Jing; Zeng, Xinyi; Yu, Danyang; Chen, Peng; Zhang, Weiguo (2025) - Integrative effects of an oral supplement mixture containing melon, yeast extract, and licorice on skin pigmentation reduction: Insights from a zebrafish model and a randomized double-blind controlled pilot human trial | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Integrative effects of an oral supplement mixture containing melon, yeast extract, and licorice on skin pigmentation reduction: Insights from a zebrafish model and a randomized double-blind controlled pilot human trial Authors Jiani Zheng Jing Sun Xinyi Zeng Danyang Yu Peng Chen Weiguo Zhang DOI: https://doi.org/10.31989/ffhd.v15i9.1747 Abstract Introduction: Intrinsic aging (e.g., genetic and metabolic changes) and extrinsic factors (e.g., sun exposure and environmental pollution) contribute to skin pigmentation and aged facial appearance. Plant extracts, known for their antioxidant properties, may influence skin pigmentation both directly and indirectly through pigment metabolism in the liver, potentially mitigating the effects of aging. Keywords: issn; pigmentation; skin

• Genetic Changes In Common Dandelion (Taraxacum officinale) Induced by High Concentrations of Heavy Metals in Soil by Babayan, Bella; Yesayan, Alexander; Sevoyan, Garegin; Yesayan, Tigran (2025) - Genetic Changes In Common Dandelion ( Taraxacum officinale ) Induced by High Concentrations of Heavy Metals in Soil | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 No. 9 (2025): September 2025 / Research Articles Genetic Changes In Common Dandelion (Taraxacum officinale) Induced by High Concentrations of Heavy Metals in Soil Authors Bella Babayan Alexander Yesayan Garegin Sevoyan Tigran Yesayan DOI: https://doi.org/10.31989/ffhd.v15i9.1753 Abstract Background: Heavy metal contamination poses a significant environmental threat in developing regions such as the Syunik Province of Armenia, where agricultural lands coexist with metal mining operations. Context and purpose of this study: The relation between heavy metal contamination of environment and DNA polymorphisms of T. officinale from Syunik, Armenia was studied. Keywords: issn; officinale

• Expression ratio of PD-1 on the T cell surface and TGF-β levels in acute and chronic brucellosis: A marker of immune evasion by Al-Zamali, Sarah; Jallod, Iman; Mohammed, Shahad; Hassan, Sara (2025) - Results: Patients with acute brucellosis exhibited significantly higher levels of PD-1 on CD4⁺ and CD8⁺ T lymphocytes than that of chronic patients and healthy individuals (P < 0.05). Patients with chronic brucellosis also showed increased PD-1 levels compared with controls. Keywords: brucellosis; tgf

• Active medicinal-food homologous complex nutrients (AMCN) enhance immune systems in zebrafish by Yuan, Yinan; Xu, Fuqiao ; Liu, Heng ; Ren, Xiaoze; Yuan, Lan (2025) - Results: AMCN treatment significantly restored immune cell populations in immunodeficient zebrafish, increasing neutrophils, macrophages, and T cells compared with the model group. Active medicinal-food homologous complex nutrients (AMCN) enhance immune systems in zebrafish | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 15 Keywords: amcn; immune

• Preparation of function-enhanced vegetable oils by Maeda, Hiroshi; Satoh, Takao; Islam, Waliul (2016) - Keywords: antioxidative components, enrichment of edible oils, lipid oxidation, dried vegetable-waste-residues. In these few decades’ vegetable oils are considered not healthy dietary components. Keywords: components; oils; residues; waste

• Neurodegenerative and Fatiguing Illnesses, Infections and Mitochondrial Dysfunction: Use of Natural Supplements to Improve Mitochondrial Function. by Nicolson, Garth L.; Settineri, Robert; Ellithorpe, Rita R. (2014) - For example, in clinical studies on chronic fatigue syndrome, fibromyalgia syndrome and other chronic fatiguing illnesses where a large majority of patients have chronic infections, LRT significantly reduced fatigue by 35-43% in different clinical trials and increased mitochondrial function.  Conclusions:  LRT formulations designed to improve mitochondrial function appear to be useful as non-toxic dietary supplements for reducing fatigue and restoring mitochondrial and other cellular membrane functions in patients with chronic illnesses and multiple chronic infections. Keywords: illnesses; infections

• Stabilization of a functional refreshment from mango nectar and yacon (Smallanthus sonchifolius) through spray drying encapsulation by Sofía, Torres-Valenzuela Laura; Rafael, Villamizar; Sara, Angel-Rendon (2014) - Universidad La Gran Colombia, Complejo Científico José Galat Noumer, Armenia Villamizar Rafael Facultad de Ingeniería. Then, 4 formulations of MN with YS with concentrations of 33.3, 66.6, and 99.9% yacon-to-juice ratio were evaluated according to the quantity of TSS, which were analyzed over the acceptance of untrained judges. Keywords: encapsulation; issn; yacon

• Krill protein hydrolysate reduces plasma triacylglycerol level with concurrent increase in plasma bile acid level and hepatic fatty acid catabolism in high-fat fed mice by Ramsvik, Marie S.; Bjørndal, Bodil; Vik, Rita; Bruheim, Inge; Skorve, Jon; Berge, Rolf K. (2013) - No. 11 (2013): November 2013 / Research Articles Krill protein hydrolysate reduces plasma triacylglycerol level with concurrent increase in plasma bile acid level and hepatic fatty acid catabolism in high-fat fed mice Authors Marie S. Ramsvik Department of Clinical Science, University of Bergen, N-5020 Bergen Bodil Bjørndal Department of Clinical Science, University of Bergen, N-5020 Bergen Rita Vik Department of Clinical Science, University of Bergen, N-5020 Bergen Inge Bruheim Olympic Seafood AS, N-6080 Myrvaag Jon Skorve Department of Clinical Science, University of Bergen, N-5020 Bergen Rolf K. Berge Department of Clinical Science, University of Bergen, N-5020 Bergen DOI: https://doi.org/10.31989/ffhd.v3i11.34 Abstract Background: Krill powder, consisting of both lipids and proteins, has been reported to modulate hepatic lipid catabolism in animals. Krill protein hydrolysate reduces plasma triacylglycerol level with concurrent increase in plasma bile acid level and hepatic fatty acid catabolism in high-fat fed mice | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 Keywords: bergen; plasma; university

• A randomized, controlled trial to assess short-term black pepper consumption on 24-hour energy expenditure and substrate utilization by O’Connor, Annalouise; Corbin, Karen D.; Nieman, David C.; Swick, Andrew G. (2013) - In vitro and rodent work suggests that components of black pepper may impact energy expenditure, and in humans, other TPRV1 agonists e.g. capsaicin, augment EE. Objectives: To determine the impact of BP on 24-hour EE, respiratory quotient, and biochemical markers of metabolism and satiety, a randomized, controlled, cross-over study of black pepper (0.5mg/meal) versus no pepper control was conducted in post-menopausal women. Keywords: carolina; north; research

• Intake of Mung Bean Protein Isolate Reduces Plasma Triglyceride Level in Rats by Tachibana, Nobuhiko; Wanezaki, Satoshi; Nagata, Mayuko; Motoyama, Takayasu; Kohno, Mitsutaka; Kitagawa, Sayuri (2013) - No. 9 (2013): September 2013 / Research Articles Intake of Mung Bean Protein Isolate Reduces Plasma Triglyceride Level in Rats Authors Nobuhiko Tachibana Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd., 1-Sumiyoshi-cho, Izumisano-shi, Osaka 598-8540 Satoshi Wanezaki Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd. Mayuko Nagata Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd. Takayasu Motoyama Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd. Mitsutaka Kohno Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd. Sayuri Kitagawa Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd. DOI: https://doi.org/10.31989/ffhd.v3i9.39 Abstract Background: Mung bean is well known as a starch source, but the physiological effects of mung bean protein have received little attention. In this study, we isolated mung bean protein from de-starched mung bean solutions, and investigated its influence on lipid metabolism. Keywords: development; fuji; research

• Efficacy and safety of Citrus sudachi peel in obese adults: A randomized, double-blind, pilot study by Akaike, Masashi; Aihara, Ken-ichi; Yanagawa, Hiroaki; Iwase, Takashi; Yoshida, Sumiko; Sato, Chiho; Saijo, Tomoka; Mikasa, Hiroaki; Kashiwada, Yoshizaki; Takaishi, Yoshihisa; Tsuchiya, Koichiro; Tamaki, Toshiaki; Matsumoto, Toshio; Sata, Masataka (2014) - No. 7 (2014): July 2014 / Research Articles Efficacy and safety of Citrus sudachi peel in obese adults: A randomized, double-blind, pilot study Authors Masashi Akaike Department of Medical Education, The University of Tokushima, Graduate School of Medical Sciences, Kuramoto-cho, Tokushima 770-8503 Ken-ichi Aihara Department of Medicine and Bioregulatroy Sciences, The University of Tokushima, Graduate School of Medical Sciences, Kuramoto-cho, Tokushima 770-8503 Hiroaki Yanagawa Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Kuramoto-cho, Tokushima 770-8503 Takashi Iwase Department of Cardiovascular Medicine, Tokushima University Hospital, Kuramoto-cho, Tokushima 770-8503 Sumiko Yoshida Department of Medicine and Bioregulatroy Sciences, Tokushima University Hospital, Kuramoto-cho, Tokushima 770-8503 Chiho Sato Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Kuramoto-cho, Tokushima 770-8503 Tomoka Saijo Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Hiroaki Mikasa Support Center for Medical Education, School of Medicine, The University of Tokushima, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Yoshizaki Kashiwada Department of Natural Medicines, The University of Tokushima, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Yoshihisa Takaishi Department of Natural Medicines, The University of Tokushima, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Koichiro Tsuchiya Department of Medical Pharmacology, The University of Tokushima, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Toshiaki Tamaki Department of Pharmacology, The University of Tokushima, Graduate School of Medical Sciences, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Toshio Matsumoto Department of Medicine and Bioregulatroy Sciences, The University of Tokushima, 3-18-15, Kuramoto-cho, Tokushima 770-8503 Masataka Sata Department of Cardiovascular Medicine, The University of Tokushima, Graduate School of Medical Sciences, 3-18-15, Kuramoto-cho, Tokushima 770-8503 DOI: https://doi.org/10.31989/ffhd.v4i7.5 Abstract Objective: This study was undertaken to explore the efficacy and safety of Citrus sudachi peel for metabolic risk factors in obese male and female adults. Accession number of the Ethics Committee for Clinical Trials of Food in Tokushima University Hospital is F5. Keywords: cho; kuramoto; tokushima

• Biography of biophenols: past, present and future by Obied, Hassan K. (2013) - Biography of biophenols: past, present and future | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 3 In this article, the author is tracing the landmarks of the history of biophenol research; profiling contemporary research directions; highlighting research controversies and uncertainties; and presenting an outlook of the biophenols future research. Keywords: biophenols; issn

• Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of Nematodes by Okuyama, Tetsuya; Yoshigai, Emi; Ikeya, Yukinobu; Nishizawa, Mikio (2013) - Epistasis analyses showed that lifespan extension by AHCC at least partly required two longevity-promoting transcription factors: DAF-16 (C. elegans homolog of FOXO) and HSF-1 (C. elegans homolog of heat shock transcription factor 1). No. 6 (2013): June 2013 / Research Articles Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of Nematodes Authors Tetsuya Okuyama Ritsumeikan Global Innovation Research Organization (R-GIRO), Ritsumeikan University, Kusatsu, Shiga, 525-8577 Emi Yoshigai Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577 Yukinobu Ikeya Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577 Mikio Nishizawa Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577 DOI: https://doi.org/10.31989/ffhd.v3i6.55 Abstract Background: Active hexose correlated compound (AHCC) is the extract from cultured mycelia of Lentinula edodes, a species of Basidiomycetes mushroom. Keywords: ahcc; heat; lifespan

• N-alkylamides: from plant to brain by Veryser, Lieselotte; Wynendaele, Evelien; Taevernier, Lien; Verbeke, Frederick; Joshib, Tanmayee; Tatke, Pratima; Spiegeleer, Bart De (2014) - Search Search Register Login Home / Archives / Vol. 4 No. 6 (2014): June 2014 / Research Articles N-alkylamides: from plant to brain Authors Lieselotte Veryser Drug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, B-9000 Ghent Evelien Wynendaele Drug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, B-9000 Ghent Lien Taevernier Drug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, B-9000 Ghent Frederick Verbeke Drug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, B-9000 Ghent Tanmayee Joshib C.U. Shah College of Pharmacy, In order to reach their pharmacodynamic targets, they have to overcome several barriers of the body in the absorption phase. Keywords: brain; ghent; university

• Antioxidant and antimicrobial activity of lecithin free egg yolk protein preparation hydrolysates obtained with digestive enzymes by Zambrowicz, Aleksandra; Pokora, Marta; Eckert, Ewelina; Szołtysik, Marek; DÄ…browska, Anna; Chrzanowska, Józefa; Trziszka, Tadeusz (2012) - Antioxidant and antimicrobial activity of lecithin free egg yolk protein preparation hydrolysates obtained with digestive enzymes | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 12 (2012): December 2012 / Research Articles Antioxidant and antimicrobial activity of lecithin free egg yolk protein preparation hydrolysates obtained with digestive enzymes Authors Aleksandra Zambrowicz Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Marta Pokora Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Ewelina Eckert Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Marek Szołtysik Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Anna DÄ…browska Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Józefa Chrzanowska Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw Tadeusz Trziszka Wroclaw University of Environmental and Life Sciences, Department of Animal Products Technology and Quality Management; Chelmonskiego 37/41, 51-630 Wroclaw DOI: https://doi.org/10.31989/ffhd.v2i12.69 Abstract Several biological activities have now been associated with egg protein- derived peptides, including antihypertensive, antimicrobial, immunomodulatory, anticancer and antioxidant activities, highlighting the importance of these biopeptides in human health, and disease prevention and treatment. Furthermore, antimicrobial properties of obtained hydrolysates against Bacillus species were studied. Keywords: life sciences; quality management; wroclaw

• Anxiolytic activity of aerial part hydroethanolic extract of Allium ascalonicum Linn. (Liliaceae) in mice by Akindele, Abidemi J.; Sanni, Hakeem A.; Edeh, Pamela C. (2012) - Objective: To investigate the anxiolytic activity of aerial part hydroethanolic extract of A. ascalonicum. Groups of mice were treated orally with distilled water (10 ml/kg), diazepam (1 mg/kg), and A. ascalonicum (50-400 mg/kg). Keywords: ascalonicum; number

• Flavocoxid (Limbrel ®) manages osteoarthritis through modification of multiple inflammatory pathways: a review by Burnett, Bruce P.; Levy, Robert M. (2012) - Flavocoxid (Limbrel ®) manages osteoarthritis through modification of multiple inflammatory pathways: a review | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 11 (2012): November 2012 / Review Articles Flavocoxid (Limbrel ®) manages osteoarthritis through modification of multiple inflammatory pathways: a review Authors Bruce P. Burnett Primus Pharmaceuticals, Inc., 4725 N. Scottsdale Road, Suite 200, Scottsdale, AZ 85251 Robert M. Levy Primus Pharmaceuticals, Inc., 4725 N. Scottsdale Road, Suite 200, Scottsdale, AZ 85251 DOI: https://doi.org/10.31989/ffhd.v2i11.74 Abstract Limbrel (flavocoxid) is marketed as an FDA-regulated medical food for the clinical dietary management of osteoarthritis (OA) to be used under physician supervision. Keywords: flavocoxid; issn; journal

• Red wine extract, resveratrol, on maintenance of organ function following trauma-hemorrhage by Liu, Fu-Chao; Yu, Huang-Ping (2012) - No. 10 (2012): October 2012 / Review Articles Red wine extract, resveratrol, on maintenance of organ function following trauma-hemorrhage Authors Fu-Chao Liu Department of Anesthesiology, Chang Gung Memorial Hospital Huang-Ping Yu Department of Anesthesiology, Chang Gung Memorial Hospital DOI: https://doi.org/10.31989/ffhd.v2i10.76 Abstract Resveratrol, is a polyphenol that can be extracted from grapes and red wine, possess potential anti-inflammatory effects, which would result in the reduction of cytokine production, the alteration of the expression of adhesion molecule molecules, and the inhibition of neutrophil function. Moreover, through anti-inflammatory effects and antioxidant properties, the resveratrol is believed to maintain organ function following trauma-hemorrhage. Keywords: issn; resveratrol

• Health benefits of olive oil and by-products and possible innovative applications for industrial processes by Centrone, Mariangela; Ranieri, Marianna; Di Mise, Annarita; D'Agostino, Mariagrazia; Venneri, Maria; Valenti, Giovanna; Tamma, Grazia (2021) - Keywords: extra virgin olive oil, by-products, olive leaf extract, bioactive compounds, human health, and industrial application Author Biographies Mariangela Centrone, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Marianna Ranieri, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Annarita Di Mise, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Mariagrazia D'Agostino, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Maria Venneri, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Giovanna Valenti, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Grazia Tamma, University of Bari Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Italy Downloads [Abstract] [Full Article] Published 2021-07-16 Issue Vol. 11 Despite the already published studies, more research is necessary to valorize bioactive compounds in olive oil and by-products, as well as their potential use to improve human health and green applications in different industrial processes.                   Keywords: bari; university

• The effect of electron beam on oxidative stress and inflammatory factors in diabetes mellitus: An in vitro and in vivo study by Martirosyan, Danik; Shahnazari-Aval, Masoomeh; Reza Ashoori, Mohammad; Seyed Mikaeili, Afsaneh; Nakhjavani, Manouchehr; Mirmiranpour, Hossein (2021) - No. 7 (2021): July 2021 / Research Articles The effect of electron beam on oxidative stress and inflammatory factors in diabetes mellitus: An in vitro and in vivo study Authors Danik Martirosyan PhD, Functional Food Institute, Dallas, TX, United States Masoomeh Shahnazari-Aval Department of Radio-Oncology, Cancer Institute, Valiasr Hospital, School of Medicine, Tehran University of Medical Science, Tehran, Iran Mohammad Reza Ashoori Department of Laboratory Sciences, School of Allied Medical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran Afsaneh Seyed Mikaeili Department of Molecular and Cellular Sciences, Faculty of Advanced Sciences and Technology, Islamic Azad University, Pharmaceutical Sciences Branch, Tehran, Iran Manouchehr Nakhjavani Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Hossein Mirmiranpour Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran DOI: https://doi.org/10.31989/ffhd.v11i7.803 Abstract Background: The main purpose of this study was to investigate whether or not electron beam therapy (EBT) was an effective method in terms of moderating oxidative stress by reducing free radicals in BALB/c mice with type 1 diabetes mellitus. Results: The results of in vitro study showed that electron beam therapy could increase glutathione reductase activity, which was not significant. Keywords: beam; electron; tehran

• Adherence to the Mediterranean diet: An online questionnaire based-study in a Spanish population sample just before the Covid-19 lockdown by Bagues, Ana; Almagro, Andrea; Bermúdez, Teresa; López-Tofiño, Yolanda; González, Antonio; Abalo, Raquel (2021) - On the other hand, the higher adherence to MD was related to older age and a higher degree of education.   Adherence to MD improved as the age in the groups increased, but so did the BMI, especially in the oldest group. Keywords: adherence; issn

• Oryza Ceramide®, a rice-derived extract consisting of glucosylceramides and β-sitosterol glucoside, improves facial skin dehydration in Japanese subjects by Takara, Tsuyoshi; Yamamoto, Kazuo; Suzuki, Naoko; Yamashita, Shinichiro; Iio, Shin-ichiro; Noguchi, Hayata; Kakinuma, Toshihiro; Baba, Asami; Takeda, Shogo; Yamada, Wakana; Shrestha, Sarita; Manse, Yoshiaki; Morikawa, Toshio; Shimoda, Hiroshi (2021) - The combination of rice GlcCer and BSG appears to be beneficial for improving facial skin conditions. Oryza Ceramide® (type PCD, 40 mg daily) containing 1.2 mg of GlcCer and 40 mg of BSG was used as the active sample. Keywords: ceramide; oryza

• Anti-salmonella potential and antioxidant activity of fermented fruit-based juice by lactic acid bacteria and its biotransformation by Laosee, Wanida; Kantachote, Duangporn; Chansuwan, Worrapanit; Thongraung, Chakree; Sirinuipong, Nualpun (2021) - Anti-salmonella potential and antioxidant activity of fermented fruit-based juice by lactic acid bacteria and its biotransformation | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 11 Worrapanit Chansuwan Center of Excellence in Functional Foods and Gastronomy, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand. Keywords: hat; songkla; university

• Preliminary study on the In-Vitro Susceptibility of Mycobacterium tuberculosis Isolates to Virgin Coconut Oil by Dalmacion, Godofreda V.; Ortega, Adelwisa R.; Pena, Imelda G.; Ang, Concepcion F. (2012) - The goal of the study was to determine the in-vitro susceptibility of M. tuberculosis (TB) isolates to two commercial brands of VCOs each containing different amounts of lauric acid and produced by two different extraction processes. Conclusion: Different VCO preparations containing different amounts of lauric acid exhibited different degree of inhibition against M. tuberculosis. Keywords: issn; manila; tuberculosis

• Effect of calafate (Berberis microphylla) supplementation on lipid profile in rats with diet-induced obesity by Guzmán, Carla; Sánchez, Raúl (2021) - No. 10 (2021): October 2021 / Research Articles Effect of calafate (Berberis microphylla) supplementation on lipid profile in rats with diet-induced obesity Authors Carla Guzmán University San Sebastian Raúl Sánchez University of La Frontera DOI: https://doi.org/10.31989/ffhd.v11i10.823 Abstract Background:  Effect of calafate (Berberis microphylla) supplementation on lipid profile in rats with diet-induced obesity | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Keywords: calafate; issn

• Starch digestibility and predicted glycemic index of fried sweet potato cultivars by Odenigbo, Amaka; Rahimi, Jamshid; Ngadi, Michael; Amer, Somaia; Mustafa, Arif (2012) - The level of total starch (TS), resistant starch (RS), digestible starch (DS), and starch digestion index starch digestion index in the samples were evaluated. There is increased interest in starch digestibility and the prevention and management of metabolic diseases. Keywords: index; starch

• An open-label, randomized clinical trial to assess the immunomodulatory activity of a novel oligosaccharide compound in healthy adults by Ali, Karriem H.; Melillo, Angelica B.; Leonard, Susanna M.; Asthana, Deshratn; Woolger, Judi M.; Wolfson, Aaron H.; McDaniel, H.; Lewis, John E. (2012) - An open-label, randomized clinical trial to assess the immunomodulatory activity of a novel oligosaccharide compound in healthy adults | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 7 (2012): July 2012 / Research Articles An open-label, randomized clinical trial to assess the immunomodulatory activity of a novel oligosaccharide compound in healthy adults Authors Karriem H. Ali Pharmacognosia, P.O. Box 971, Rainier, WA 98576 Angelica B. Melillo Department of Psychiatry & Behavioral Sciences at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 Susanna M. Leonard Department of Psychiatry & Behavioral Sciences at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 Deshratn Asthana Department of Psychiatry & Behavioral Sciences at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 Judi M. Woolger Department of Medicine at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 Aaron H. Wolfson Department of Radiation Oncology at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 H. McDaniel Fisher Institute for Medical Research, 2701 Osler Dr Suite 6B Grand Prairie, TX 75051 John E. Lewis Department of Psychiatry & Behavioral Sciences at University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136 DOI: https://doi.org/10.31989/ffhd.v2i7.84 Abstract Background: Rice Bran Arabinoxylan Compound (RBAC) is a nutritional supplement produced by enzymatic hydrolysis of hemicellulose B derived from rice bran. RBAC may not only help to destroy tumor cells and viruses directly, but also increase the activity of immune cells, thereby optimizing the immune system, especially NKCC, which can increase the chance and speed of host recovery. Keywords: 14th street; miami; nw 14th

• In vitro Alpha-amylase inhibition, antioxidant, nutritional and sensory properties of functional spice-blend fortified cookies by Otunola, Gloria Aderonke; Afolayan, Anthony Jide (2022) - Keywords: cookies, functional foods, hyperglycemia, sensory, bioactive compounds Author Biographies Gloria Aderonke Otunola, University of Fort Hare, South Africa Medicinal Plants and Economic Development (MPED) Research Centre, Department of Botany, University of Fort Hare, Alice 5700, South Africa Anthony Jide Afolayan, University of Fort Hare, South Africa Medicinal Plants and Economic Development (MPED) Research Centre, Department of Botany, University of Fort Hare, Alice 5700, South Africa Downloads [Abstract] [Full Article] Published 2022-02-03 Issue Vol. 12 No. 2 (2022): February 2022 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. In vitro Alpha-amylase inhibition, antioxidant, nutritional and sensory properties of functional spice-blend fortified cookies | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 2 (2022): February 2022 / Research Articles In vitro Alpha-amylase inhibition, antioxidant, nutritional and sensory properties of functional spice-blend fortified cookies Authors Gloria Aderonke Otunola University of Fort Hare, South Africa http://orcid.org/0000-0003-2613-2741 Anthony Jide Afolayan University of Fort Hare, South Africa DOI: https://doi.org/10.31989/ffhd.v12i2.845 Abstract Introduction: Fortification of foods is often performed to formulate and develop functional foods that improve the nutritional and health status of consumers.      Keywords: cookies; fort; spice

• Functional and quality attributes of beef burgers fortified by brown linseed powder by Basiri, Sara; Yousefi, Mohamamd Hashem; Shekarforoush, Seyed Shahram (2022) - Functional and quality attributes of beef burgers fortified by brown linseed powder | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 1 (2022): January 2022 / Research Articles Functional and quality attributes of beef burgers fortified by brown linseed powder Authors Sara Basiri Mohamamd Hashem Yousefi Seyed Shahram Shekarforoush DOI: https://doi.org/10.31989/ffhd.v12i1.855 Abstract Background: Beef burgers are a popular food all over the world. Keywords: issn; linseed

• A review on the health benefits of Monechma ciliatum (Black mahlab): A potential functional food by Mariod, Abdalbasit Adam; Mustafa, Eshraga Mustafa A.; Yahia, Marwa Bushra (2022) - A review on the health benefits of Monechma ciliatum (Black mahlab): A potential functional food | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 2 (2022): February 2022 / Review Articles A review on the health benefits of Monechma ciliatum (Black mahlab): A potential functional food Authors Abdalbasit Adam Mariod Eshraga Mustafa A. Mustafa Marwa Bushra Yahia DOI: https://doi.org/10.31989/ffhd.v12i2.879 Abstract Background: Monechma ciliatum (MC) (Acanthaceae family) is a herb that grows in tropical and subtropical regions. Keywords: Monechma ciliatum, black mahlab, nutritional, antioxidants, Antimicrobial, oxytocic Downloads [Abstract] [Full Article] Published 2022-02-09 Issue Vol. 12 No. 2 (2022): February 2022 Section Review Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. Keywords: ciliatum; monechma

• Effect of an oral probiotic formula on scalp and facial skin condition, glucose, and lipid metabolism by Yu, Peng; Teng, Xiaoyue; Liu, Tingzhu; Li, Yuhan; Ni, Jiayi; Xue, Siliang; Wang, Juan (2022) - Teng Harbin Institute of Technology Tingzhu Liu Memoo (Beijing) Technology Co. Ltd. Yuhan Li Memoo (Beijing) Technology Co. Ltd. Jiayi Ni Sprim (China) Consulting Co. Ltd. Siliang Xue West China Hospital of Sichuan University Juan Wang Memoo (Beijing) Technology Co. Ltd. DOI: https://doi.org/10.31989/ffhd.v12i7.944 Abstract Objective: We conducted this study to explore the effect of oral probiotic supplementation on hair density as a primary outcome in subjects with hair loss and at high risk of metabolic syndrome. Keywords: hair density, hair loss, metabolic syndrome, oral probiotic supplementation Author Biographies Peng Yu, West China Hospital of Sichuan University Department of Dermatology Xiaoyue Teng, Harbin Institute of Technology School of Chemistry and Chemical Engineering Siliang Xue, West China Hospital of Sichuan University Department of Dermatology Downloads {Abstract} {Full Article} Keywords: density; hair; issn; loss

• Epigenetic active phytoceuticals activate immune relevant miRNAs important in virus response systems by Hippe, Berit; Krammer, Ulrike; Modder, Franziska; Mayer, Anna; Speich, Sandra; Gruber, Urs; Jacob, Ursula; Haslberger, Alexander (2022) - Methods: In a 2-month human intervention study (n=80), a mix of plant extracts (sage extract, green tea extract, berberine, apple extract, onion extract, elderberry extract, and grape skin extract) with proven activity against RNA viruses were examined for the change of miRNA and mRNA patterns involved in virus response systems. Functional foods as plant extracts (nutraceuticals) are epigenetically active, and multi-target antiviral compounds that affect several steps of the viral life cycle and host proteins. Keywords: austria; university; vienna

• A randomized, controlled trial on the effectiveness of a proprietary marine lipo-peptide formula vs omega-3 on cytokines profile, anxiety, and pain symptoms in patients with fibromyalgia by Rastmanesh, Reza; Solimene, Umberto; Lorenzetti, Aldo; Marotta, Francesco; Fang, HE; Aperio, Cristiana; Anzulovic, Nevenka; Cervi, Giuseppe; Zerbinati, Nicola (2022) - DOI: https://doi.org/10.31989/ffhd.v12i8.954 Abstract Objective: The aim of the present study in an RCT manner (physicians and patients) a novel lipo-peptide marine compound, LD-1227, on physical-, emotional- and functional-related symptomatic complaints in fibromyalgia patients as well as inflammatory cytokines profile and gene expression while using omega-3 as a control group. A randomized, controlled trial on the effectiveness of a proprietary marine lipo-peptide formula vs omega-3 on cytokines profile, anxiety, and pain symptoms in patients with fibromyalgia | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 8 (2022): August 2022 / Research Articles A randomized, controlled trial on the effectiveness of a proprietary marine lipo-peptide formula vs omega-3 on cytokines profile, anxiety, and pain symptoms in patients with fibromyalgia Authors Reza Rastmanesh The Nutrition Society, London, UK Umberto Solimene WHO-collaborating Center for WHO-cntr forTraditional Medicine & Biotechnology, University of Milano, Milano, Italy Aldo Lorenzetti Senior researcher, Regenera Intl. Keywords: fibromyalgia; issn; pain

• Mechanism Prediction of Gastro-protective Effects of the Biebersteinia multifida against Ethanol-Induced Gastric Ulcers; an Insilco study by Zarchi, Saeed Rezaei; Dousti, Mahdi; Rezazadeh, Davood; Sajadi, Elham; Rizvand, Sara; Roozbahani, Narges Eskandari (2022) - Molecular Medicine Department, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran Elham Sajadi Ph.D. of Physiology, Department of Basic Science, School of veterinary medicine, Shiraz University, Shiraz, Iran. Objective: This study was performed to predict the possible mechanism of action of BM bioactive compounds on ameliorating ethanolic PUD in an Insilico study by molecular docking. Keywords: iran; issn; university

• Effect of spinach-derived glutathione against carbon tetrachloride-induced stress in rats by Abdulkareem Abdulrazak, Enas; Jameel, Qaswaa Yousif (2022) - Administration of milk with glutathione derived from Iraqi spinach leaves exhibited favorable effects on oxidative stress, greatly enhanced the antioxidant system, and protected rats from liver damage brought on by carbon tetrachloride compared to milk with synthetic glutathione.  Keywords: Iraqi spinach, Functional food, Natural antioxidant, Oxidative stress, synthetic glutathione.  Keywords: glutathione; spinach

• Anti-ulcer activity of Ipomoea batatas tubers (sweet potato) by Panda, Vandana; Sonkamble, Madhav (2012) - Anti-ulcer activity of Ipomoea batatas tubers (sweet potato) | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 2 No. 3 (2012): March 2012 / Research Articles Anti-ulcer activity of Ipomoea batatas tubers (sweet potato) Authors Vandana Panda Department of Pharmacology & Toxicology, Prin. Ipomoea batatas tubers (sweet potato) contain ample amounts of antioxidants. Keywords: batatas; ipomoea; ulcer

Epilogue

For more detail, about this study carrel, see the computed home page. For more detail about study carrels in general, see the read me file.

Created: 2025-12-24