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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 1 No. 12 (2011): December 2011
				
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									Research Articles
							
		



	
		  	 

		
	
		Supplementation of Powdered Black Cumin (Nigella sativa) Seeds Reduces the Risk of Hypercholesterolemia
	


	
	
		

							
					Authors

						
							
								M. Tauseef Sultan
							
															
									Department of Food Sciences, Bahauddin Z akariya University Multan
																	
																																		
	
							
								Masood Sadiq Butt
							
															
									National Institute of Food Science and Technology, University of Agriculture, Faisalabad
																	
																																		
	
							
								Rabia Shabeer Ahmad
							
															
									Department of Food Sciences, GC University, Faisalabad
																	
																																		
	
							
								Rizwana Batool
							
															
									National Institute of Food Science and Technology, University of Agriculture, Faisalabad
																	
																																		
	
							
								Ambreen Naz
							
															
									National Institute of Food Science and Technology, University of Agriculture, Faisalabad
																	
																																		
	
							
								Hafiz Suleria
							
															
									National Institute of Food Science and Technology, University of Agriculture, Faisalabad
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v1i12.109
						
					
				
			

						
										
					Abstract

					Background: Functional and nutraceutical foods are gaining immense popularity among the masses. Plants and their bioactive molecules are of prime importance. Although various plants from different geographical areas have been tested in the past, many horizons still need to be addressed. Black cumin (Nigella sativa L.) is one such example that is quite popular in South Asia and the Middle East.
Context and purpose: The present research study was designed to expedite the role of black cumin seed in reducing the risk of hypercholesterolemia. For the purpose, thirty Sprague dawley rats were procured from the National Institute of Health (NIH) in Islamabad, Pakistan, and further split up into three groups, (10 rats each). Experimental diets were prepared using powdered black cumin (PBC) at 1% and 2%, and compared with the placebo. 
Results: The results revealed that PBC was effective in reducing the serum cholesterol, triglycerides, and low-density lipoproteins (LDL). Additionally, the experimental diets resulted in a non-significant increase in high-density lipoprotein (HDL). Overall, powdered black cumin at 1% and 2% reduced cholesterol level by 6.73, and 4.48%, LDL by 24.79, and 24.32% respectively. However, the supplementation of PBC at 2% resulted in marked variations as increasing tendency, which was recorded for cholesterol and triglycerides contents after 28 days of study. 
Conclusion: Present research investigation brightened the prospects of using powdered black cumin seed in diet based therapies to improve the lipid profile. Further studies are still required to assess the phytochemistry of the plants and indeed the functional ingredients responsible for such health benefits. Such studies would bring meticulousness for utilization of black cumin seeds as a functional food.
Keywords: Functional foods, black cumin, lipid profile, cholesterol, triglycerides

				
			
			

						
																																																						
						
		


		

						
										
					
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																			2011-12-30
																	

				
							

			
						
										

											
							
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									Vol. 1 No. 12 (2011): December 2011
								
							

						
					
											
							
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								Research Articles
							

						
					
									

			
						
										
					
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