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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 1 No. 8 (2011): August 2011
				
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									Research Articles
							
		



	
		  	 

		
	
		Lipid Replacement Therapy Drink Containing a Glycophospholipid Formulation Rapidly and Significantly Reduces Fatigue While Improving Energy and Mental Clarity
	


	
	
		

							
					Authors

						
							
								Rita R. Ellithorpe
							
															
									Tustin Longevity Center, Tustin, California 92780
																	
																																		
	
							
								Robert Settineri
							
															
									Sierra Research, Irvine, California 92606
																	
																																		
	
							
								Cyndee A. Mitchell
							
															
									Tustin Longevity Center, Tustin, California 92780
																	
																																		
	
							
								Brett Jacques
							
															
									Tustin Longevity Center, Tustin, California 92780
																	
																																		
	
							
								Erin Ellithorpe
							
															
									Tustin Longevity Center, Tustin, California 92780
																	
																																		
	
							
								Garth L. Nicolson
							
															
									Department of Molecular Pathology, The Institute for Molecular Medicine, Huntington Beach, California 92647
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v1i8.126
						
					
				
			

						
										
					Abstract

					Background: Fatigue is the most common complaint of patients seeking general medical care and is often treated with stimulants. It is also important in various physical activities of relatively healthy men and women, such as sports performance. Recent clinical trials using patients with chronic fatigue have shown the benefit of Lipid Replacement Therapy in restoring mitochondrial electron transport function and reducing moderate to severe chronic fatigue. 
Methods: Lipid Replacement Therapy was administered for the first time as an all-natural functional food drink (60 ml) containing polyunsaturated glycophospholipids but devoid of stimulants or herbs to reduce fatigue. This preliminary study used the Piper Fatigue Survey instrument as well as a supplemental questionnaire to assess the effects of the glycophospholipid drink on fatigue and the acceptability of the test drink in adult men and women. A volunteer group of 29 subjects of mean age 56.2±4.5 years with various fatigue levels were randomly recruited in a clinical health fair setting to participate in an afternoon open label trial on the effects of the test drink. 
Results: Using the Piper Fatigue instrument overall fatigue among participants was reduced within the 3-hour seminar by a mean of 39.6% (p<0.0001). All of the subcategories of fatigue showed significant reductions. Some subjects responded within 15 minutes, and the majority responded within one hour with increased energy and activity and perceived improvements in cognitive function, mental clarity and focus. The test drink was determined to be quite acceptable in terms of taste and appearance. There were no adverse events from the energy drink during the study.
Conclusions: The Lipid Replacement Therapy functional food drink appeared to be a safe, acceptable and potentially useful new method to reduce fatigue, sustain energy and improve perceptions of mental function.
Keywords: functional food drink, NT Factor®, NT Factor Lipids®, fatigue, mitochondrial function, mental function

				
			
			

						
																																																						
						
		


		

						
										
					
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																			2011-08-29
																	

				
							

			
						
										

											
							
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									Vol. 1 No. 8 (2011): August 2011
								
							

						
					
											
							
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