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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 5 No. 5 (2015): May 2015
				
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									Short Report
							
		



	
		  	 

		
	
		Randomized, double-blind, placebo-controlled, crossover study to evaluate the  effects of beta-1,3/1,6 glucan on stress associated with daily lifestyle in healthy  subjects
	


	
	
		

							
					Authors

						
							
								Yoshihiko Ojiri
							
															
									Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan
																	
																																		
	
							
								Hiroshi Endoh
							
															
									Faculty of Education and Graduate School of Education, University of the Ryukyus, Nishihara, Okinawa 
903-0213, Japan
																	
																																		
	
							
								Tadashi Okumoto
							
															
									Faculty of Human Health Sciences, Meio University, Nago, Okinawa 905-8585, 
Japan
																	
																																		
	
							
								Kazushi Atsuta
							
															
									Chuko Awamori Distillery Co., Ltd., Tomigusuku, Okinawa 901-0235, Japan
																	
																																		
	
							
								Orie Yoshinari
							
															
									The Japanese 
Institute for Health Food Standards, 6-26-12 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
																	
																																		
	
							
								Hiroyoshi Moriyama
							
															
									The Japanese 
Institute for Health Food Standards, 6-26-12 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v5i5.179
						
					
				
			

						
										
					Abstract

					Background: Fatigue is attributable to physical and psychological stress. Fatigue is also a common symptom which occurs in both sick and healthy individuals. Although its mechanism of cause is complex, fatigue from stress is known to affect the existing equilibrium of the immune system. However, nutrition, such as beta-1,3/1,6 glucan, has been reported to play an important role in regulating stress and fatigue states, via modulating a weakened immune system. In this study, a popular and healthy beverage in Okinawa, Japan, containing a soluble baker’s yeast in black koji vinegar (Moromisu), was provided to healthy subjects with a non-strenuous daily lifestyle.
Results: By performing statistical analysis on the results of the Profile of Mood States (POMS) survey, we observed that overall study results (n=14) demonstrated significant differences in fatigue and confusion in the POMS factors.
Conclusions: In this study we confirmed that beta-1,3/1,6 glucan improved some of the factors related to stress and fatigue, as indicated by evaluation of POMS survey results.
Key Words: Beta-1,3/1,6-glucan, vinegar, POMS, stress

				
			
			

						
																																																						
						
		


		

						
										
					
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																			2015-05-27
																	

				
							

			
						
										

											
							
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									Vol. 5 No. 5 (2015): May 2015
								
							

						
					
											
							
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