





































































The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys  glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy  overweight participants
							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
	Skip to main content
	Skip to main navigation menu
		Skip to site footer


			

				
					
						Open Menu
					
										
																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
					Home
				
										
									
										Food Science Publisher
									
								
	
									
										Functional Food Center
									
								


							
	
				
					Current
				
							
	
				
					Archives
				
							
	
				
					About
				
										
									
										About the Journal
									
								
	
									
										Aims and Scope
									
								
	
									
										Contact
									
								
	
									
										Editing Services
									
								
	
									
										Editorial Team
									
								
	
									
										Express Peer Review
									
								
	
									
										Graphical Abstract
									
								
	
									
										Journal Insights
									
								
	
									
										Privacy Statement
									
								
	
									
										Submissions
									
								


							
	
				
					Announcements
				
							
	
				
					Search
				
							



				

																						
									
										
										Search
									
								

													

					

					
								
				
					Register
				
							
	
				
					Login
				
							



					

				
			

		

						
			
				


			
		
			
				Home
			
			/
		
	
			
				Archives
			
			/
		
	
				
					Vol. 5 No. 6 (2015): June 2015
				
				/
			
	
			
									Research Articles
							
		



	
		  	 

		
	
		The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys  glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy  overweight participants
	


	
	
		

							
					Authors

						
							
								Boris Azantsa
							
															
									Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, SW Region, Cameroon;Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon;
																	
																																		
	
							
								Dieudonne Kuate
							
															
									Program in Nutrition, School of Health Sciences Universiti Sains Malaysia, 16150 Kubang Kerian Kelantan, Malaysia;
																	
																																		
	
							
								Raoul Chakokam
							
															
									Department of Biochemistry, Faculty of 
Science, BP 812, University of Yaounde 1, Yaounde, Cameroon;
																	
																																		
	
							
								Ghislain Paka
							
															
									Department of Biochemistry, Faculty of 
Science, BP 812, University of Yaounde 1, Yaounde, Cameroon;
																	
																																		
	
							
								Barbara Bartholomew
							
															
									PhytoQuest Limited, Plas 
Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK
																	
																																		
	
							
								Robert Nash
							
															
									PhytoQuest Limited, Plas 
Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v5i6.184
						
					
				
			

						
										
					Abstract

					Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Considering the physio-metabolic changes that accompany obesity, the present study investigates the effects of these extracts on healthy overweight participants over an 8-week test period.
Methods: The study was an 8 week randomized double-blind, placebo controlled design involving 48 overweight (BMI 26 – 30) participants (27 females and 19 males), divided into 3 groups – placebo, 300 mg I. gabonensis extract (IGOB131), or 300 mg D. glomerata extract (DyglomeraTM). Capsules containing the placebo or the test formulations were administered once daily before the main meal of the day. No major dietary changes or changes in physical activity were demonstrated during the study. Weight and blood lipid parameters were measured at baseline, and at the 4 and 8 weeks interval.
Results: Compared to the placebo group, there were significant (p<0.05) reductions in weight of participants in both test groups over the 8 week period. However, these significant changes were not observed in the initial 4 weeks, even though the lipid parameters in the test groups changed significantly (p<0.05).
Conclusion: The extracts of Irvingia gabonensis and Dichrostachys glomerata, at a dose of 300 mg per day, were effective in reducing weight and positively modifying lipid parameters in healthy overweight participants.
Keywords: Overweight, Dichrostachys, Irvingia, waist-hip circumference, blood lipids.

				
			
			

						
																																																						
						
		


		

						
										
					
						Downloads
					

						
								
	
													


		
	[Abstract]

	
							
	
								
	
													


		
	[Full Article]

	
							


				

						
						
				
					
						Published
					

					
																			2015-06-09
																	

				
							

			
						
										

											
							
								Issue
							

							
								
									Vol. 5 No. 6 (2015): June 2015
								
							

						
					
											
							
								Section
							

							
								Research Articles
							

						
					
									

			
						
										
					
						License
					

										Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License.

This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged.

By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained.

				

			
			

		

	




	




	


							



	

	

					
				About the Journal      Editing Services      Graphical Abstract      Journal Insights        Submissions        Editorial Team       Privacy Statement        Contact        Current        Archives

 

			

		
		Open Journal Systems Hosting and Support by: OpenJournalSystems.com


	










