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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 3 No. 9 (2013): September 2013
				
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									Research Articles
							
		



	
		  	 

		
	
		Intake of Mung Bean Protein Isolate Reduces Plasma Triglyceride Level in Rats
	


	
	
		

							
					Authors

						
							
								Nobuhiko Tachibana
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd., 1-Sumiyoshi-cho, Izumisano-shi, Osaka 598-8540
																	
																																		
	
							
								Satoshi Wanezaki
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd.
																	
																																		
	
							
								Mayuko Nagata
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd.
																	
																																		
	
							
								Takayasu Motoyama
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd.
																	
																																		
	
							
								Mitsutaka Kohno
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd.
																	
																																		
	
							
								Sayuri Kitagawa
							
															
									Basic Research Institute, Research and Development Division, Fuji Oil Co., Ltd.
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v3i9.39
						
					
				
			

						
										
					Abstract

					Background: Mung bean is well known as a starch source, but the physiological effects of mung bean protein have received little attention. In this study, we isolated mung bean protein from de-starched mung bean solutions, and investigated its influence on lipid metabolism.
 
Objective: The aim of this study is to clarify the influence of the lipid metabolism by consumption of mung bean protein isolate (MPI)

Methods: Diets containing either mung bean protein isolate (MPI) or casein were fed to normal rats for 28 days.

Results: Both groups ate the same amount of food, but the plasma triglyceride level, relative liver weight and liver lipid contents (cholesterol and triglyceride pool) in the MPI group were significantly lower than in the casein group. In the MPI group, the expression of sterol regulatory-element binding factor 1 (SREBF1) mRNA in the liver was significantly different when compared with the casein group. The significantly lower levels of insulin and free fatty acids in the MPI-fed rats may be due to the regulation of genes related to lipid metabolism in the liver.

Conclusions: These results suggest that MPI may improve the plasma lipid profile by normalizing insulin sensitivity.
Keywords: mung bean, Vigna radiata L., 8S globulin, triglyceride, β-conglycinin, 7S globulin, insulin sensitivity, SREBF1

				
			
			

						
																																																						
						
		


		

						
										
					
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																			2013-09-30
																	

				
							

			
						
										

											
							
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									Vol. 3 No. 9 (2013): September 2013
								
							

						
					
											
							
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								Research Articles
							

						
					
									

			
						
										
					
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