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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 3 No. 9 (2013): September 2013
				
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									Research Articles
							
		



	
		  	 

		
	
		The Potential Anti Helicobacter pylori and antioxidant effects of Artemisia Judaica
	


	
	
		

							
					Authors

						
							
								M. Adel El-Sayed
							
															
									Pharmacology department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA
																	
																																		
	
							
								Radwan BaAbbad
							
															
									Medical Microbiology departments, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA
																	
																																		
	
							
								Amal Balash
							
															
									Biochemistry department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA
																	
																																		
	
							
								Nasser A. Al-Hemdan
							
															
									Community Medicine department, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA
																	
																																		
	
							
								Abdullah Softah
							
															
									Undergraduate Medical Student, Faculty of Medicine, King Saud Bin Abdulaziz University for Health Sciences, KSA
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v3i9.42
						
					
				
			

						
										
					Abstract

					Artemisia judaica (AJ) is one of the common species of the genus Artemisia that grows in Saudi Arabia desert and Sinai, Egypt where animals graze on it. It is widely used in traditional medicine and by Bedouins there. (AJ) has anthelmintic, antibacterial, antiinflammatory, analgesic and antipyretic effects. The present study aimed to (1) elucidates the antibacterial action of AJ against H. pylori and different other bacterial species (2) delineate the potential antibacterial mechanism of action of AJ in comparison with tetracycline and cefotaxime (3) measure the trolox equivalent antioxidant capacity (TEAC) of the AJ water extract. Preparation of the (AJ) extracts was done by three different methods two of them are usually performed by population in Middle East by boiling of the shade-dried herb in water as tea (decoction), or soaked in tap water for over night (infusion), other method was done by concentrating the aqueous extract of Artemisia judaica under vacuum. The results of this study revealed that (AJ) has neither antibacterial effects either against H. pylorinor any other bacterial species. On the other hand the extract of AJ prepared by any of the above mentioned methods shows significant (p<0.005) antioxidant action as compared with blank and related to trolox antioxidant capacity.

				
			
			

						
																																															
						
		


		

						
										
					
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																			2013-09-26
																	

				
							

			
						
										

											
							
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									Vol. 3 No. 9 (2013): September 2013
								
							

						
					
											
							
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								Research Articles
							

						
					
									

			
						
										
					
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