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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 2 No. 10 (2012): October 2012
				
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									Review Articles
							
		



	
		  	 

		
	
		Red wine extract, resveratrol, on maintenance of organ function following trauma-hemorrhage
	


	
	
		

							
					Authors

						
							
								Fu-Chao Liu
							
															
									Department of Anesthesiology, Chang Gung Memorial Hospital
																	
																																		
	
							
								Huang-Ping Yu
							
															
									Department of Anesthesiology, Chang Gung Memorial Hospital
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v2i10.76
						
					
				
			

						
										
					Abstract

					Resveratrol, is a polyphenol that can be extracted from grapes and red wine, possess potential anti-inflammatory effects, which would result in the reduction of cytokine production, the alteration of the expression of adhesion molecule molecules, and the inhibition of neutrophil function. Resveratrol might also act as an antioxidant, anti-aging, and control of cell cycle and apoptosis. Resveratrol has been shown to have protective effects for patients in shock-like states. Such protective phenomenon is reported to be implicated in a variety of intracellular signaling pathways including the regulation of the mitogen-activated protein kinases (MAPK)/ hemeoxygenase-1 (HO-1) pathway, activates estrogen receptor (ER), and the mediation of pro-inflammatory cytokines, reactive oxygen species (ROS) formation and reactive. Moreover, through anti-inflammatory effects and antioxidant properties, the resveratrol is believed to maintain organ function following trauma-hemorrhage.

Key words: resveratrol, anti-inflammatory, trauma-hemorrhage.

				
			
			

						
																										
						
		


		

						
										
					
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																			2012-10-23
																	

				
							

			
						
										

											
							
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									Vol. 2 No. 10 (2012): October 2012
								
							

						
					
											
							
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