







































































Effect of calafate (Berberis microphylla) supplementation on lipid profile in rats with diet-induced obesity
							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
	Skip to main content
	Skip to main navigation menu
		Skip to site footer


			

				
					
						Open Menu
					
										
																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
					Home
				
										
									
										Food Science Publisher
									
								
	
									
										Functional Food Center
									
								


							
	
				
					Current
				
							
	
				
					Archives
				
							
	
				
					About
				
										
									
										About the Journal
									
								
	
									
										Aims and Scope
									
								
	
									
										Contact
									
								
	
									
										Editing Services
									
								
	
									
										Editorial Team
									
								
	
									
										Express Peer Review
									
								
	
									
										Graphical Abstract
									
								
	
									
										Journal Insights
									
								
	
									
										Privacy Statement
									
								
	
									
										Submissions
									
								


							
	
				
					Announcements
				
							
	
				
					Search
				
							



				

																						
									
										
										Search
									
								

													

					

					
								
				
					Register
				
							
	
				
					Login
				
							



					

				
			

		

						
			
				


			
		
			
				Home
			
			/
		
	
			
				Archives
			
			/
		
	
				
					Vol. 11 No. 10 (2021): October 2021
				
				/
			
	
			
									Research Articles
							
		



	
		  	 

		
	
		Effect of calafate (Berberis microphylla) supplementation on lipid profile in rats with diet-induced obesity
	


	
	
		

							
					Authors

						
							
								Carla Guzmán
							
															
									University San Sebastian
																	
																																		
	
							
								Raúl Sánchez
							
															
									University of La Frontera
																	
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v11i10.823
						
					
				
			

						
										
					Abstract

					Background: Polyphenols represent a group of bioactive compounds of interest for their efficacy in the prevention and treatment of some diseases of a cardiovascular nature. Calafate (Berberis microphylla) is a native Chilean fruit, promising due to its high number of phenolic compounds, with predominance of anthocyanins delphinidin-3-hexoside and petunidin-3-hexoside. 
 
Methods: Sprague Dawley rats fed a high-fat diet (HFD) were supplemented with 350 mg/kg of freeze-dried calafate for 10 weeks. Dietary variables, plasma glucose, lipid profile, as well as atherogenic and cardiovascular risk indexes were measured. 
 
Results: Animals receiving calafate with their HFD diet compared to the HFD control was not associated with significant modifications in dietary variables or in total cholesterol and triglyceride concentrations. However, due to the modest elevation of high-density lipoproteins, the Atherogenic Index and the Cardiovascular Risk Index were significantly decreased. 
 
Conclusion: Based on these results, the calafate could have an antithrombotic function, favoring cardiovascular health.
 
Keywords: High-fat diet, polyphenols, calafate berry, HDL-cholesterol, Atherogenic Index
				
			
			

						
																																																
					
													Author Biographies
											

						
								
																																							Carla Guzmán,  University San Sebastian 
																	

								
									Faculty of Health Care Sciencies. University San Sebastian
Academic Nutrition and Dietetics Career
 
 
								

							
	
								
																																							Raúl Sánchez,  University of La Frontera 
																	

								
									Faculty of Medicine. University of La Frontera.
Academic Program in Medical Sciencies.

								

							


				
			
						
		


		

						
										
					
						Downloads
					

						
								
	
													


		
	[Abstract]

	
							
	
								
	
													


		
	[Full Article]

	
							


				

						
						
				
					
						Published
					

					
																			2021-10-05
																	

				
							

			
						
										

											
							
								Issue
							

							
								
									Vol. 11 No. 10 (2021): October 2021
								
							

						
					
											
							
								Section
							

							
								Research Articles
							

						
					
									

			
						
										
					
						License
					

										Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License.

This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged.

By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained.

				

			
			

		

	




	




	


							



	

	

					
				About the Journal      Editing Services      Graphical Abstract      Journal Insights        Submissions        Editorial Team       Privacy Statement        Contact        Current        Archives

 

			

		
		Open Journal Systems Hosting and Support by: OpenJournalSystems.com


	










