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							| Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007



	

				
						
 
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																Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007
										

				


				
				
					
					
						
																					
				
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					Vol. 11 No. 12 (2021): December 2021
				
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									Research Articles
							
		



	
		  	 

		
	
		Effect of combining sleep-promoting food intake and electric field application on sleep in healthy participants: A pilot study
	


	
	
		

							
					Authors

						
							
								Takaki Nedachi
							
																																		
	
							
								Kaoru Haketa
							
																																		
	
							
								Shinji Harakawa
							
																																		
	
							
								Naoki Miura
							
																																		
	
							
								Koji Wakame
							
																																		


				
			
																	
					
												DOI:
					

					
						
							https://doi.org/10.31989/ffhd.v11i12.861
						
					
				
			

						
										
					Abstract

					Background: Functional foods and electric fields (EFs) have been previously reported as interventions for insomnia other than medications. As for functional foods, gamma-aminobutyric acid (GABA) and lafma have been reported to be related to sleep. EFs have also been reported to have a sleep-related, anti-stress effect in mouse model experiments. However, the effects of combining these two methods on the human body remain poorly studied. 
Objective: Thus, this study aimed to investigate the cointervention effect of sleep-promoting functional food intake and EF application on sleep quality in healthy participants. 
Methods: Fifteen healthy participants were divided into three groups. The Food and Placebo groups were given active tablets containing food mixture of GABA and lafma, and placebo tablets, respectively, for 4 weeks. Meanwhile, the Food plus EF group used an EF therapy device during sleep in addition to the active food tablets. Sleep quality was evaluated using electroencephalography and sleep questionnaires.
Results: Sleep efficiency (SE) was significantly higher in the Food group and the Food plus EF group than the Placebo group at 4 weeks. The Food plus EF group also had a significantly higher SE involving sleep latency. 
Conclusions: Food mixture containing known sleep-promoting ingredients such as GABA and lafma can improve sleep quality, and the improvement effect can be enhanced when administered in combination with an EF.
Keywords: electric field therapy, Kumasasa (Sasa senanensis), electric fields, sleep quality, electroencephalography
Clinical trial registration: Approval No.: R1812; Approval date: 21 Feb. 2019

				
			
			

						
																																															
						
		


		

						
										
					
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																			2021-12-16
																	

				
							

			
						
										

											
							
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									Vol. 11 No. 12 (2021): December 2021
								
							

						
					
											
							
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								Research Articles
							

						
					
									

			
						
										
					
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