id sid tid token lemma pos ffhd-108 1 1 curcumin curcumin NOUN ffhd-108 1 2 and and CCONJ ffhd-108 1 3 egcg egcg VERB ffhd-108 1 4 suppress suppress VERB ffhd-108 1 5 apurinic apurinic ADJ ffhd-108 1 6 / / SYM ffhd-108 1 7 apyrimidinic apyrimidinic ADJ ffhd-108 1 8 endonuclease endonuclease NOUN ffhd-108 1 9 1 1 NUM ffhd-108 1 10 and and CCONJ ffhd-108 1 11 induce induce VERB ffhd-108 1 12 complete complete ADJ ffhd-108 1 13 remission remission NOUN ffhd-108 1 14 in in ADP ffhd-108 1 15 b b NOUN ffhd-108 1 16 - - PUNCT ffhd-108 1 17 cell cell NOUN ffhd-108 1 18 non non ADJ ffhd-108 1 19 - - ADJ ffhd-108 1 20 hodgkin hodgkin NOUN ffhd-108 1 21 's 's PART ffhd-108 1 22 lymphoma lymphoma NOUN ffhd-108 1 23 patients patient NOUN ffhd-108 1 24 | | ADV ffhd-108 1 25 functional functional ADJ ffhd-108 1 26 foods food NOUN ffhd-108 1 27 in in ADP ffhd-108 1 28 health health NOUN ffhd-108 1 29 and and CCONJ ffhd-108 1 30 disease disease PROPN ffhd-108 1 31 online online PROPN ffhd-108 1 32 issn issn PROPN ffhd-108 1 33 : : PUNCT ffhd-108 1 34 2160 2160 NUM ffhd-108 1 35 - - SYM ffhd-108 1 36 3855 3855 NUM ffhd-108 1 37 ; ; PUNCT ffhd-108 1 38 print print NOUN ffhd-108 1 39 issn issn PROPN ffhd-108 1 40 : : PUNCT ffhd-108 1 41 2378 2378 NUM ffhd-108 1 42 - - SYM ffhd-108 1 43 7007 7007 NUM ffhd-108 1 44 skip skip NOUN ffhd-108 1 45 to to ADP ffhd-108 1 46 main main ADJ ffhd-108 1 47 content content NOUN ffhd-108 1 48 skip skip ADJ ffhd-108 1 49 to to ADP ffhd-108 1 50 main main ADJ ffhd-108 1 51 navigation navigation NOUN ffhd-108 1 52 menu menu NOUN ffhd-108 1 53 skip skip VERB ffhd-108 1 54 to to PART ffhd-108 1 55 site site VERB ffhd-108 1 56 footer footer ADJ ffhd-108 1 57 open open ADJ ffhd-108 1 58 menu menu NOUN ffhd-108 1 59 functional functional ADJ ffhd-108 1 60 foods food NOUN ffhd-108 1 61 in in ADP ffhd-108 1 62 health health NOUN ffhd-108 1 63 and and CCONJ ffhd-108 1 64 disease disease PROPN ffhd-108 1 65 online online PROPN ffhd-108 1 66 issn issn PROPN ffhd-108 1 67 : : PUNCT ffhd-108 1 68 2160 2160 NUM ffhd-108 1 69 - - SYM ffhd-108 1 70 3855 3855 NUM ffhd-108 1 71 ; ; PUNCT ffhd-108 1 72 print print NOUN ffhd-108 1 73 issn issn PROPN ffhd-108 1 74 : : PUNCT ffhd-108 1 75 2378 2378 NUM ffhd-108 1 76 - - SYM ffhd-108 1 77 7007 7007 NUM ffhd-108 1 78 home home NOUN ffhd-108 1 79 food food NOUN ffhd-108 1 80 science science NOUN ffhd-108 1 81 publisher publisher NOUN ffhd-108 1 82 functional functional ADJ ffhd-108 1 83 food food NOUN ffhd-108 1 84 center center NOUN ffhd-108 1 85 current current ADJ ffhd-108 1 86 archives archive NOUN ffhd-108 1 87 about about ADP ffhd-108 1 88 about about ADP ffhd-108 1 89 the the DET ffhd-108 1 90 journal journal NOUN ffhd-108 1 91 aims aim VERB ffhd-108 1 92 and and CCONJ ffhd-108 1 93 scope scope NOUN ffhd-108 1 94 contact contact NOUN ffhd-108 1 95 editing edit VERB ffhd-108 1 96 services service NOUN ffhd-108 1 97 editorial editorial ADJ ffhd-108 1 98 team team NOUN ffhd-108 1 99 express express VERB ffhd-108 1 100 peer peer NOUN ffhd-108 1 101 review review NOUN ffhd-108 1 102 graphical graphical ADJ ffhd-108 1 103 abstract abstract ADJ ffhd-108 1 104 journal journal NOUN ffhd-108 1 105 insights insight VERB ffhd-108 1 106 privacy privacy NOUN ffhd-108 1 107 statement statement NOUN ffhd-108 1 108 submissions submission NOUN ffhd-108 1 109 announcements announcement NOUN ffhd-108 1 110 search search NOUN ffhd-108 1 111 search search NOUN ffhd-108 1 112 register register NOUN ffhd-108 1 113 login login NOUN ffhd-108 1 114 home home NOUN ffhd-108 1 115 / / SYM ffhd-108 1 116 archives archive NOUN ffhd-108 1 117 / / SYM ffhd-108 1 118 vol vol NOUN ffhd-108 1 119 . . NOUN ffhd-108 1 120 1 1 NUM ffhd-108 2 1 no no NOUN ffhd-108 2 2 . . PROPN ffhd-108 2 3 12 12 NUM ffhd-108 2 4 ( ( PUNCT ffhd-108 2 5 2011 2011 NUM ffhd-108 2 6 ): ): PUNCT ffhd-108 2 7 december december PROPN ffhd-108 2 8 2011 2011 NUM ffhd-108 2 9 / / SYM ffhd-108 2 10 research research NOUN ffhd-108 2 11 articles article NOUN ffhd-108 2 12 curcumin curcumin NOUN ffhd-108 2 13 and and CCONJ ffhd-108 2 14 egcg egcg VERB ffhd-108 2 15 suppress suppress VERB ffhd-108 2 16 apurinic apurinic ADJ ffhd-108 2 17 / / SYM ffhd-108 2 18 apyrimidinic apyrimidinic ADJ ffhd-108 2 19 endonuclease endonuclease NOUN ffhd-108 2 20 1 1 NUM ffhd-108 2 21 and and CCONJ ffhd-108 2 22 induce induce VERB ffhd-108 2 23 complete complete ADJ ffhd-108 2 24 remission remission NOUN ffhd-108 2 25 in in ADP ffhd-108 2 26 b b NOUN ffhd-108 2 27 - - PUNCT ffhd-108 2 28 cell cell NOUN ffhd-108 2 29 non non ADJ ffhd-108 2 30 - - ADJ ffhd-108 2 31 hodgkin hodgkin NOUN ffhd-108 2 32 's 's PART ffhd-108 2 33 lymphoma lymphoma NOUN ffhd-108 2 34 patients patient NOUN ffhd-108 2 35 authors author NOUN ffhd-108 2 36 ahmad ahmad PROPN ffhd-108 2 37 r. r. PROPN ffhd-108 2 38 bassiouny bassiouny PROPN ffhd-108 2 39 department department PROPN ffhd-108 2 40 of of ADP ffhd-108 2 41 biochemistry biochemistry NOUN ffhd-108 2 42 , , PUNCT ffhd-108 2 43 faculty faculty NOUN ffhd-108 2 44 of of ADP ffhd-108 2 45 science science NOUN ffhd-108 2 46 , , PUNCT ffhd-108 2 47 alexandria alexandria PROPN ffhd-108 2 48 university university PROPN ffhd-108 2 49 mona mona PROPN ffhd-108 2 50 a. a. PROPN ffhd-108 2 51 atteya atteya PROPN ffhd-108 2 52 department department PROPN ffhd-108 2 53 of of ADP ffhd-108 2 54 biochemistry biochemistry NOUN ffhd-108 2 55 , , PUNCT ffhd-108 2 56 faculty faculty NOUN ffhd-108 2 57 of of ADP ffhd-108 2 58 science science NOUN ffhd-108 2 59 , , PUNCT ffhd-108 2 60 alexandria alexandria PROPN ffhd-108 2 61 university university PROPN ffhd-108 2 62 fatma fatma PROPN ffhd-108 2 63 h. h. PROPN ffhd-108 2 64 el el PROPN ffhd-108 2 65 - - PUNCT ffhd-108 2 66 rashidy rashidy VERB ffhd-108 2 67 department department NOUN ffhd-108 2 68 of of ADP ffhd-108 2 69 biochemistry biochemistry NOUN ffhd-108 2 70 , , PUNCT ffhd-108 2 71 faculty faculty NOUN ffhd-108 2 72 of of ADP ffhd-108 2 73 science science NOUN ffhd-108 2 74 , , PUNCT ffhd-108 2 75 alexandria alexandria PROPN ffhd-108 2 76 university university PROPN ffhd-108 2 77 hashem hashem PROPN ffhd-108 2 78 m. m. PROPN ffhd-108 2 79 neenaa neenaa PROPN ffhd-108 2 80 department department PROPN ffhd-108 2 81 of of ADP ffhd-108 2 82 internal internal ADJ ffhd-108 2 83 medicine medicine NOUN ffhd-108 2 84 , , PUNCT ffhd-108 2 85 hematological hematological ADJ ffhd-108 2 86 disease disease NOUN ffhd-108 2 87 unit unit NOUN ffhd-108 2 88 , , PUNCT ffhd-108 2 89 faculty faculty NOUN ffhd-108 2 90 of of ADP ffhd-108 2 91 medicine medicine NOUN ffhd-108 2 92 , , PUNCT ffhd-108 2 93 alexandria alexandria PROPN ffhd-108 2 94 university university PROPN ffhd-108 2 95 doi doi PROPN ffhd-108 2 96 : : PUNCT ffhd-108 2 97 https://doi.org/10.31989/ffhd.v1i12.108 https://doi.org/10.31989/ffhd.v1i12.108 ADJ ffhd-108 2 98 abstract abstract ADJ ffhd-108 2 99 background background NOUN ffhd-108 2 100 : : PUNCT ffhd-108 2 101 follicular follicular ADJ ffhd-108 2 102 lymphoma lymphoma NOUN ffhd-108 2 103 ( ( PUNCT ffhd-108 2 104 fl fl NOUN ffhd-108 2 105 ) ) PUNCT ffhd-108 2 106 is be AUX ffhd-108 2 107 the the DET ffhd-108 2 108 most most ADV ffhd-108 2 109 common common ADJ ffhd-108 2 110 subtype subtype NOUN ffhd-108 2 111 of of ADP ffhd-108 2 112 indolent indolent ADJ ffhd-108 2 113 lymphoma lymphoma NOUN ffhd-108 2 114 . . PUNCT ffhd-108 3 1 fl fl PROPN ffhd-108 3 2 is be AUX ffhd-108 3 3 still still ADV ffhd-108 3 4 considered consider VERB ffhd-108 3 5 to to PART ffhd-108 3 6 be be AUX ffhd-108 3 7 an an DET ffhd-108 3 8 incurable incurable ADJ ffhd-108 3 9 disease disease NOUN ffhd-108 3 10 and and CCONJ ffhd-108 3 11 palliation palliation NOUN ffhd-108 3 12 of of ADP ffhd-108 3 13 symptoms symptom NOUN ffhd-108 3 14 is be AUX ffhd-108 3 15 an an DET ffhd-108 3 16 acceptable acceptable ADJ ffhd-108 3 17 approach approach NOUN ffhd-108 3 18 to to ADP ffhd-108 3 19 the the DET ffhd-108 3 20 expected expect VERB ffhd-108 3 21 pattern pattern NOUN ffhd-108 3 22 of of ADP ffhd-108 3 23 repeated repeat VERB ffhd-108 3 24 relapses relapse NOUN ffhd-108 3 25 due due ADJ ffhd-108 3 26 to to ADP ffhd-108 3 27 developing develop VERB ffhd-108 3 28 resistance resistance NOUN ffhd-108 3 29 to to ADP ffhd-108 3 30 chemotherapy chemotherapy NOUN ffhd-108 3 31 agents agent NOUN ffhd-108 3 32 . . PUNCT ffhd-108 4 1 apurinic apurinic ADJ ffhd-108 4 2 / / SYM ffhd-108 4 3 apyrimidinic apyrimidinic ADJ ffhd-108 4 4 endonuclease endonuclease NOUN ffhd-108 4 5 / / SYM ffhd-108 4 6 redox redox NOUN ffhd-108 4 7 factor-1 factor-1 PROPN ffhd-108 4 8 ( ( PUNCT ffhd-108 4 9 ape1 ape1 NOUN ffhd-108 4 10 / / SYM ffhd-108 4 11 ref-1 ref-1 PRON ffhd-108 4 12 ) ) PUNCT ffhd-108 4 13 is be AUX ffhd-108 4 14 a a DET ffhd-108 4 15 multifunctional multifunctional ADJ ffhd-108 4 16 protein protein NOUN ffhd-108 4 17 involved involve VERB ffhd-108 4 18 in in ADP ffhd-108 4 19 dna dna PROPN ffhd-108 4 20 base base NOUN ffhd-108 4 21 excision excision NOUN ffhd-108 4 22 repair repair NOUN ffhd-108 4 23 ( ( PUNCT ffhd-108 4 24 ber ber NOUN ffhd-108 4 25 ) ) PUNCT ffhd-108 4 26 of of ADP ffhd-108 4 27 oxidative oxidative ADJ ffhd-108 4 28 dna dna NOUN ffhd-108 4 29 damage damage NOUN ffhd-108 4 30 and and CCONJ ffhd-108 4 31 in in ADP ffhd-108 4 32 redox redox ADJ ffhd-108 4 33 regulation regulation NOUN ffhd-108 4 34 of of ADP ffhd-108 4 35 a a DET ffhd-108 4 36 number number NOUN ffhd-108 4 37 of of ADP ffhd-108 4 38 transcription transcription NOUN ffhd-108 4 39 factors factor NOUN ffhd-108 4 40 . . PUNCT ffhd-108 5 1 it it PRON ffhd-108 5 2 was be AUX ffhd-108 5 3 observed observe VERB ffhd-108 5 4 that that SCONJ ffhd-108 5 5 cytoplasmic cytoplasmic ADJ ffhd-108 5 6 ape1 ape1 NOUN ffhd-108 5 7 induced induce VERB ffhd-108 5 8 cox-2 cox-2 DET ffhd-108 5 9 expression expression NOUN ffhd-108 5 10 through through ADP ffhd-108 5 11 nf nf ADJ ffhd-108 5 12 - - PUNCT ffhd-108 5 13 κb κb NOUN ffhd-108 5 14 activation activation NOUN ffhd-108 5 15 . . PUNCT ffhd-108 6 1 it it PRON ffhd-108 6 2 has have AUX ffhd-108 6 3 been be AUX ffhd-108 6 4 shown show VERB ffhd-108 6 5 that that SCONJ ffhd-108 6 6 chemopreventive chemopreventive ADJ ffhd-108 6 7 agents agent NOUN ffhd-108 6 8 potentiate potentiate VERB ffhd-108 6 9 the the DET ffhd-108 6 10 efficacy efficacy NOUN ffhd-108 6 11 of of ADP ffhd-108 6 12 chemotherapy chemotherapy NOUN ffhd-108 6 13 through through ADP ffhd-108 6 14 the the DET ffhd-108 6 15 regulation regulation NOUN ffhd-108 6 16 of of ADP ffhd-108 6 17 multiple multiple ADJ ffhd-108 6 18 signaling signal VERB ffhd-108 6 19 pathways pathway NOUN ffhd-108 6 20 , , PUNCT ffhd-108 6 21 including include VERB ffhd-108 6 22 nf nf NOUN ffhd-108 6 23 - - PUNCT ffhd-108 6 24 κb κb NOUN ffhd-108 6 25 , , PUNCT ffhd-108 6 26 c c NOUN ffhd-108 6 27 - - PUNCT ffhd-108 6 28 myc myc NOUN ffhd-108 6 29 , , PUNCT ffhd-108 6 30 cyclooxygenase-2 cyclooxygenase-2 X ffhd-108 6 31 , , PUNCT ffhd-108 6 32 apoptosis apoptosis NOUN ffhd-108 6 33 , , PUNCT ffhd-108 6 34 and and CCONJ ffhd-108 6 35 others other NOUN ffhd-108 6 36 , , PUNCT ffhd-108 6 37 suggesting suggest VERB ffhd-108 6 38 a a DET ffhd-108 6 39 multitargeted multitargeted ADJ ffhd-108 6 40 nature nature NOUN ffhd-108 6 41 of of ADP ffhd-108 6 42 chemopreventive chemopreventive ADJ ffhd-108 6 43 agents agent NOUN ffhd-108 6 44 . . PUNCT ffhd-108 7 1 we we PRON ffhd-108 7 2 hypothesized hypothesize VERB ffhd-108 7 3 that that SCONJ ffhd-108 7 4 curcumin curcumin NOUN ffhd-108 7 5 , , PUNCT ffhd-108 7 6 a a DET ffhd-108 7 7 polyphenolic polyphenolic ADJ ffhd-108 7 8 antioxidant antioxidant NOUN ffhd-108 7 9 derived derive VERB ffhd-108 7 10 from from ADP ffhd-108 7 11 the the DET ffhd-108 7 12 spice spice NOUN ffhd-108 7 13 turmeric turmeric NOUN ffhd-108 7 14 , , PUNCT ffhd-108 7 15 and and CCONJ ffhd-108 7 16 epigallocatechin epigallocatechin PROPN ffhd-108 7 17 gallate gallate PROPN ffhd-108 7 18 ( ( PUNCT ffhd-108 7 19 egcg egcg NOUN ffhd-108 7 20 ) ) PUNCT ffhd-108 7 21 from from ADP ffhd-108 7 22 green green ADJ ffhd-108 7 23 tea tea NOUN ffhd-108 7 24 would would AUX ffhd-108 7 25 potentiate potentiate VERB ffhd-108 7 26 the the DET ffhd-108 7 27 effect effect NOUN ffhd-108 7 28 of of ADP ffhd-108 7 29 chemotherapy chemotherapy NOUN ffhd-108 7 30 in in ADP ffhd-108 7 31 b b NOUN ffhd-108 7 32 - - PUNCT ffhd-108 7 33 cell cell NOUN ffhd-108 7 34 lymphoma lymphoma NOUN ffhd-108 7 35 . . PUNCT ffhd-108 8 1 objective objective NOUN ffhd-108 8 2 : : PUNCT ffhd-108 9 1 we we PRON ffhd-108 9 2 examined examine VERB ffhd-108 9 3 the the DET ffhd-108 9 4 role role NOUN ffhd-108 9 5 of of ADP ffhd-108 9 6 human human ADJ ffhd-108 9 7 apurinic apurinic ADJ ffhd-108 9 8 / / SYM ffhd-108 9 9 apyrimidinic apyrimidinic ADJ ffhd-108 9 10 endonuclease endonuclease NOUN ffhd-108 9 11 1 1 NUM ffhd-108 9 12 ( ( PUNCT ffhd-108 9 13 ape1 ape1 NOUN ffhd-108 9 14 ) ) PUNCT ffhd-108 9 15 in in ADP ffhd-108 9 16 resistance resistance NOUN ffhd-108 9 17 and and CCONJ ffhd-108 9 18 prognosis prognosis NOUN ffhd-108 9 19 in in ADP ffhd-108 9 20 patients patient NOUN ffhd-108 9 21 with with ADP ffhd-108 9 22 fl fl PROPN ffhd-108 9 23 . . PUNCT ffhd-108 10 1 our our PRON ffhd-108 10 2 major major ADJ ffhd-108 10 3 objective objective NOUN ffhd-108 10 4 was be AUX ffhd-108 10 5 to to PART ffhd-108 10 6 update update VERB ffhd-108 10 7 the the DET ffhd-108 10 8 safety safety NOUN ffhd-108 10 9 and and CCONJ ffhd-108 10 10 efficacy efficacy NOUN ffhd-108 10 11 results result NOUN ffhd-108 10 12 of of ADP ffhd-108 10 13 the the DET ffhd-108 10 14 antitumor antitumor PROPN ffhd-108 10 15 effect effect NOUN ffhd-108 10 16 of of ADP ffhd-108 10 17 combination combination NOUN ffhd-108 10 18 of of ADP ffhd-108 10 19 curcumin curcumin NOUN ffhd-108 10 20 and and CCONJ ffhd-108 10 21 egcg egcg NOUN ffhd-108 10 22 therapy therapy NOUN ffhd-108 10 23 in in ADP ffhd-108 10 24 relapsed relapse VERB ffhd-108 10 25 or or CCONJ ffhd-108 10 26 resistant resistant ADJ ffhd-108 10 27 indolent indolent ADJ ffhd-108 10 28 or or CCONJ ffhd-108 10 29 transformed transform VERB ffhd-108 10 30 non non ADJ ffhd-108 10 31 - - ADJ ffhd-108 10 32 hodgkin hodgkin ADJ ffhd-108 10 33 follicular follicular ADJ ffhd-108 10 34 lymphoma lymphoma NOUN ffhd-108 10 35 patients patient NOUN ffhd-108 10 36 and and CCONJ ffhd-108 10 37 their their PRON ffhd-108 10 38     SPACE ffhd-108 10 39 peripheral peripheral ADJ ffhd-108 10 40 blood blood NOUN ffhd-108 10 41 mononuclear mononuclear ADJ ffhd-108 10 42 cells cell NOUN ffhd-108 10 43 ( ( PUNCT ffhd-108 10 44 pbmcs pbmcs NOUN ffhd-108 10 45 ) ) PUNCT ffhd-108 10 46 compared compare VERB ffhd-108 10 47 with with ADP ffhd-108 10 48 healthy healthy ADJ ffhd-108 10 49 donors donor NOUN ffhd-108 10 50 ’ ' PUNCT ffhd-108 10 51 controls control NOUN ffhd-108 10 52 . . PUNCT ffhd-108 11 1 methods method NOUN ffhd-108 11 2 : : PUNCT ffhd-108 11 3 thirty thirty NUM ffhd-108 11 4 patients patient NOUN ffhd-108 11 5 with with ADP ffhd-108 11 6 fl fl NUM ffhd-108 11 7 with with ADP ffhd-108 11 8 over over ADP ffhd-108 11 9 - - PUNCT ffhd-108 11 10 expression expression NOUN ffhd-108 11 11 of of ADP ffhd-108 11 12 constitutive constitutive ADJ ffhd-108 11 13 active active ADJ ffhd-108 11 14 nf nf NOUN ffhd-108 11 15 - - PUNCT ffhd-108 11 16 κb κb NOUN ffhd-108 11 17 in in ADP ffhd-108 11 18 their their PRON ffhd-108 11 19 pbmcs pbmcs NOUN ffhd-108 11 20 received receive VERB ffhd-108 11 21 regular regular ADJ ffhd-108 11 22 chop chop NOUN ffhd-108 11 23 and and CCONJ ffhd-108 11 24 consumed consume VERB ffhd-108 11 25 capsules capsule NOUN ffhd-108 11 26 compatible compatible ADJ ffhd-108 11 27 with with ADP ffhd-108 11 28 curcumin curcumin NOUN ffhd-108 11 29 doses dose NOUN ffhd-108 11 30     SPACE ffhd-108 11 31 between between ADP ffhd-108 11 32 0.9 0.9 NUM ffhd-108 11 33 and and CCONJ ffhd-108 11 34 5.4 5.4 NUM ffhd-108 11 35 g g NOUN ffhd-108 11 36 daily daily ADV ffhd-108 11 37 for for ADP ffhd-108 11 38 up up ADP ffhd-108 11 39 to to PART ffhd-108 11 40 9 9 NUM ffhd-108 11 41 months month NOUN ffhd-108 11 42 and and CCONJ ffhd-108 11 43 9.0 9.0 NUM ffhd-108 11 44 g g NOUN ffhd-108 11 45 / / SYM ffhd-108 11 46 day day NOUN ffhd-108 11 47 green green ADJ ffhd-108 11 48 tea tea PROPN ffhd-108 11 49 whole whole ADJ ffhd-108 11 50 extract extract NOUN ffhd-108 11 51 " " PUNCT ffhd-108 11 52 1000 1000 NUM ffhd-108 11 53 mg mg NOUN ffhd-108 11 54 tablets tablet NOUN ffhd-108 11 55 of of ADP ffhd-108 11 56 green green ADJ ffhd-108 11 57 tea tea NOUN ffhd-108 11 58 whole whole ADJ ffhd-108 11 59 extract extract NOUN ffhd-108 11 60 containing contain VERB ffhd-108 11 61 200 200 NUM ffhd-108 11 62 mg mg PROPN ffhd-108 11 63 egcg egcg NOUN ffhd-108 11 64 . . PUNCT ffhd-108 12 1 we we PRON ffhd-108 12 2 designed design VERB ffhd-108 12 3 a a DET ffhd-108 12 4 dose dose NOUN ffhd-108 12 5 - - PUNCT ffhd-108 12 6 escalation escalation NOUN ffhd-108 12 7     SPACE ffhd-108 12 8 study study NOUN ffhd-108 12 9 to to PART ffhd-108 12 10 explore explore VERB ffhd-108 12 11 the the DET ffhd-108 12 12 efficacy efficacy NOUN ffhd-108 12 13 of of ADP ffhd-108 12 14 chop chop NOUN ffhd-108 12 15 in in ADP ffhd-108 12 16 combination combination NOUN ffhd-108 12 17 with with ADP ffhd-108 12 18 curcumin curcumin NOUN ffhd-108 12 19 and and CCONJ ffhd-108 12 20 the the DET ffhd-108 12 21 green green ADJ ffhd-108 12 22 tea tea NOUN ffhd-108 12 23 extract extract NOUN ffhd-108 12 24 epigallocatechin-3 epigallocatechin-3 PROPN ffhd-108 12 25 gallate gallate NOUN ffhd-108 12 26 ( ( PUNCT ffhd-108 12 27 egcg egcg NOUN ffhd-108 12 28 ) ) PUNCT ffhd-108 12 29 on on ADP ffhd-108 12 30 the the DET ffhd-108 12 31 viability viability NOUN ffhd-108 12 32 of of ADP ffhd-108 12 33 patients patient NOUN ffhd-108 12 34 ’ ' PUNCT ffhd-108 12 35 peripheral peripheral ADJ ffhd-108 12 36 blood blood NOUN ffhd-108 12 37 mononuclear mononuclear ADJ ffhd-108 12 38 cells cell NOUN ffhd-108 12 39 ( ( PUNCT ffhd-108 12 40 pbmcs pbmcs NOUN ffhd-108 12 41 ) ) PUNCT ffhd-108 12 42 lymphocytes lymphocyte NOUN ffhd-108 12 43 . . PUNCT ffhd-108 13 1 results result NOUN ffhd-108 13 2 : : PUNCT ffhd-108 13 3 treatment treatment NOUN ffhd-108 13 4 of of ADP ffhd-108 13 5 patients patient NOUN ffhd-108 13 6 with with ADP ffhd-108 13 7 the the DET ffhd-108 13 8 combination combination NOUN ffhd-108 13 9 of of ADP ffhd-108 13 10 curcumin curcumin NOUN ffhd-108 13 11 and and CCONJ ffhd-108 13 12 egcg egcg NOUN ffhd-108 13 13 , , PUNCT ffhd-108 13 14 significantly significantly ADV ffhd-108 13 15 lower low ADJ ffhd-108 13 16 cytoplasmic cytoplasmic ADJ ffhd-108 13 17 ape1 ape1 NOUN ffhd-108 13 18 and and CCONJ ffhd-108 13 19 the the DET ffhd-108 13 20 levels level NOUN ffhd-108 13 21 of of ADP ffhd-108 13 22 the the DET ffhd-108 13 23 transcription transcription NOUN ffhd-108 13 24 factor factor NOUN ffhd-108 13 25 were be AUX ffhd-108 13 26 lower low ADJ ffhd-108 13 27 than than ADP ffhd-108 13 28 those those PRON ffhd-108 13 29 predicted predict VERB ffhd-108 13 30 from from ADP ffhd-108 13 31 the the DET ffhd-108 13 32 effects effect NOUN ffhd-108 13 33 of of ADP ffhd-108 13 34 the the DET ffhd-108 13 35 chop chop NOUN ffhd-108 13 36 agents agent NOUN ffhd-108 13 37 ( ( PUNCT ffhd-108 13 38 cyclophosphamide cyclophosphamide PROPN ffhd-108 13 39 , , PUNCT ffhd-108 13 40 doxorubicin doxorubicin PROPN ffhd-108 13 41 , , PUNCT ffhd-108 13 42 vincristine vincristine NOUN ffhd-108 13 43 , , PUNCT ffhd-108 13 44 and and CCONJ ffhd-108 13 45 prednisone prednisone NOUN ffhd-108 13 46 ) ) PUNCT ffhd-108 13 47 alone alone ADV ffhd-108 13 48 , , PUNCT ffhd-108 13 49 especially especially ADV ffhd-108 13 50 with with ADP ffhd-108 13 51 a a DET ffhd-108 13 52 blunting blunting NOUN ffhd-108 13 53 of of ADP ffhd-108 13 54 the the DET ffhd-108 13 55 remarkable remarkable ADJ ffhd-108 13 56 increases increase NOUN ffhd-108 13 57 in in ADP ffhd-108 13 58 nfκb nfκb ADJ ffhd-108 13 59 activation activation NOUN ffhd-108 13 60 induced induce VERB ffhd-108 13 61 by by ADP ffhd-108 13 62 chop chop NOUN ffhd-108 13 63 . . PUNCT ffhd-108 14 1 eighteen eighteen NUM ffhd-108 14 2 of of ADP ffhd-108 14 3 the the DET ffhd-108 14 4 patients patient NOUN ffhd-108 14 5 had have VERB ffhd-108 14 6 a a DET ffhd-108 14 7 cr cr NOUN ffhd-108 14 8 ( ( PUNCT ffhd-108 14 9 18/30 18/30 NUM ffhd-108 14 10 ) ) PUNCT ffhd-108 14 11 , , PUNCT ffhd-108 14 12 and and CCONJ ffhd-108 14 13 twelve twelve NUM ffhd-108 14 14 patients patient NOUN ffhd-108 14 15 had have AUX ffhd-108 14 16 pr pr X ffhd-108 14 17 ( ( PUNCT ffhd-108 14 18 12/30 12/30 NUM ffhd-108 14 19 ) ) PUNCT ffhd-108 14 20 within within ADP ffhd-108 14 21 9 9 NUM ffhd-108 14 22 month month NOUN ffhd-108 14 23 treatment treatment NOUN ffhd-108 14 24 and and CCONJ ffhd-108 14 25 followed follow VERB ffhd-108 14 26 up up ADP ffhd-108 14 27 to to PART ffhd-108 14 28 12 12 NUM ffhd-108 14 29 months month NOUN ffhd-108 14 30 . . PUNCT ffhd-108 15 1 they they PRON ffhd-108 15 2 remain remain VERB ffhd-108 15 3 disease disease NOUN ffhd-108 15 4 - - PUNCT ffhd-108 15 5 free free ADJ ffhd-108 15 6 a a DET ffhd-108 15 7 mean mean NOUN ffhd-108 15 8 of of ADP ffhd-108 15 9 8.6 8.6 NUM ffhd-108 15 10 y y PROPN ffhd-108 15 11 ( ( PUNCT ffhd-108 15 12 range range PROPN ffhd-108 15 13 , , PUNCT ffhd-108 15 14 7.9–9.2 7.9–9.2 NOUN ffhd-108 15 15 y y X ffhd-108 15 16 ) ) PUNCT ffhd-108 15 17 after after ADP ffhd-108 15 18 this this DET ffhd-108 15 19 combination combination NOUN ffhd-108 15 20 therapy therapy NOUN ffhd-108 15 21 . . PUNCT ffhd-108 16 1 conclusion conclusion NOUN ffhd-108 16 2 : : PUNCT ffhd-108 16 3 optimal optimal ADJ ffhd-108 16 4 patient patient ADJ ffhd-108 16 5 benefit benefit NOUN ffhd-108 16 6 might might AUX ffhd-108 16 7 be be AUX ffhd-108 16 8 obtained obtain VERB ffhd-108 16 9 in in ADP ffhd-108 16 10 follicular follicular ADJ ffhd-108 16 11 lymphoma lymphoma NOUN ffhd-108 16 12 when when SCONJ ffhd-108 16 13 administering administer VERB ffhd-108 16 14 curcumin curcumin NOUN ffhd-108 16 15 up up ADP ffhd-108 16 16 - - PUNCT ffhd-108 16 17 front front NOUN ffhd-108 16 18 in in ADP ffhd-108 16 19 combination combination NOUN ffhd-108 16 20 with with ADP ffhd-108 16 21 chemotherapy chemotherapy NOUN ffhd-108 16 22 and and CCONJ ffhd-108 16 23 egcg egcg NOUN ffhd-108 16 24 treatment treatment NOUN ffhd-108 16 25 . . PUNCT ffhd-108 17 1 the the DET ffhd-108 17 2 combination combination NOUN ffhd-108 17 3 of of ADP ffhd-108 17 4 curcumin curcumin NOUN ffhd-108 17 5 with with ADP ffhd-108 17 6 egcg egcg NOUN ffhd-108 17 7 resulted result VERB ffhd-108 17 8 in in ADP ffhd-108 17 9 a a DET ffhd-108 17 10 synergistic synergistic ADJ ffhd-108 17 11 antitumor antitumor NOUN ffhd-108 17 12 activity activity NOUN ffhd-108 17 13 and and CCONJ ffhd-108 17 14 that that SCONJ ffhd-108 17 15 with with ADP ffhd-108 17 16 chop chop NOUN ffhd-108 17 17 agents agent NOUN ffhd-108 17 18 in in ADP ffhd-108 17 19 additivity additivity NOUN ffhd-108 17 20 or or CCONJ ffhd-108 17 21 sub sub NOUN ffhd-108 17 22 - - ADJ ffhd-108 17 23 additivity additivity ADJ ffhd-108 17 24 , , PUNCT ffhd-108 17 25 down down ADV ffhd-108 17 26 - - PUNCT ffhd-108 17 27 regulated regulate VERB ffhd-108 17 28 the the DET ffhd-108 17 29 expression expression NOUN ffhd-108 17 30 of of ADP ffhd-108 17 31 all all DET ffhd-108 17 32 nf nf ADJ ffhd-108 17 33 - - PUNCT ffhd-108 17 34 κb κb NOUN ffhd-108 17 35 regulated regulated ADJ ffhd-108 17 36 gene gene NOUN ffhd-108 17 37 products product NOUN ffhd-108 17 38 , , PUNCT ffhd-108 17 39 leading lead VERB ffhd-108 17 40 to to ADP ffhd-108 17 41 the the DET ffhd-108 17 42 suppression suppression NOUN ffhd-108 17 43 of of ADP ffhd-108 17 44 angiogenesis angiogenesis NOUN ffhd-108 17 45 , , PUNCT ffhd-108 17 46 metastasis metastasis NOUN ffhd-108 17 47 and and CCONJ ffhd-108 17 48 entering enter VERB ffhd-108 17 49 in in ADP ffhd-108 17 50 complete complete ADJ ffhd-108 17 51 remission remission NOUN ffhd-108 17 52 as as SCONJ ffhd-108 17 53 indicated indicate VERB ffhd-108 17 54 by by ADP ffhd-108 17 55 β2 β2 PROPN ffhd-108 17 56 - - PUNCT ffhd-108 17 57 microglobulin microglobulin PROPN ffhd-108 17 58 and and CCONJ ffhd-108 17 59 lactate lactate PROPN ffhd-108 17 60 dehydrogenase dehydrogenase NOUN ffhd-108 17 61 ( ( PUNCT ffhd-108 17 62 ldh ldh PROPN ffhd-108 17 63 ) ) PUNCT ffhd-108 17 64 levels level NOUN ffhd-108 17 65 . . PUNCT ffhd-108 18 1 key key ADJ ffhd-108 18 2 words word NOUN ffhd-108 18 3 : : PUNCT ffhd-108 18 4 curcumin curcumin NOUN ffhd-108 18 5 , , PUNCT ffhd-108 18 6 egcg egcg NOUN ffhd-108 18 7 , , PUNCT ffhd-108 18 8 bcell bcell PROPN ffhd-108 18 9 nhl nhl PROPN ffhd-108 18 10 , , PUNCT ffhd-108 18 11 nf nf PROPN ffhd-108 18 12 - - PUNCT ffhd-108 18 13 κb κb PROPN ffhd-108 18 14 , , PUNCT ffhd-108 18 15 vegf vegf PROPN ffhd-108 18 16 , , PUNCT ffhd-108 18 17 ape1 ape1 PROPN ffhd-108 18 18 , , PUNCT ffhd-108 18 19 lymphoma lymphoma NOUN ffhd-108 18 20 downloads download VERB ffhd-108 19 1 [ [ X ffhd-108 19 2 abstract abstract X ffhd-108 19 3 ] ] X ffhd-108 20 1 [ [ X ffhd-108 20 2 full full ADJ ffhd-108 20 3 article article NOUN ffhd-108 20 4 ] ] PUNCT ffhd-108 20 5 published publish VERB ffhd-108 20 6 2011 2011 NUM ffhd-108 20 7 - - SYM ffhd-108 20 8 12 12 NUM ffhd-108 20 9 - - SYM ffhd-108 20 10 30 30 NUM ffhd-108 20 11 issue issue NOUN ffhd-108 20 12 vol vol NOUN ffhd-108 20 13 . . PROPN ffhd-108 20 14 1 1 NUM ffhd-108 21 1 no no NOUN ffhd-108 21 2 . . PROPN ffhd-108 21 3 12 12 NUM ffhd-108 21 4 ( ( PUNCT ffhd-108 21 5 2011 2011 NUM ffhd-108 21 6 ): ): PUNCT ffhd-108 21 7 december december PROPN ffhd-108 21 8 2011 2011 NUM ffhd-108 21 9 section section NOUN ffhd-108 21 10 research research NOUN ffhd-108 21 11 articles article NOUN ffhd-108 21 12 license license NOUN ffhd-108 21 13 authors author NOUN ffhd-108 21 14 retain retain VERB ffhd-108 21 15 the the DET ffhd-108 21 16 copyright copyright NOUN ffhd-108 21 17 of of ADP ffhd-108 21 18 their their PRON ffhd-108 21 19 articles article NOUN ffhd-108 21 20 and and CCONJ ffhd-108 21 21 grant grant VERB ffhd-108 21 22 the the DET ffhd-108 21 23 functional functional ADJ ffhd-108 21 24 food food NOUN ffhd-108 21 25 center center NOUN ffhd-108 21 26 ( ( PUNCT ffhd-108 21 27 ffc ffc NOUN ffhd-108 21 28 ) ) PUNCT ffhd-108 21 29 and and CCONJ ffhd-108 21 30 its its PRON ffhd-108 21 31 journals journal NOUN ffhd-108 21 32 the the DET ffhd-108 21 33 right right NOUN ffhd-108 21 34 of of ADP ffhd-108 21 35 first first ADJ ffhd-108 21 36 publication publication NOUN ffhd-108 21 37 under under ADP ffhd-108 21 38 the the DET ffhd-108 21 39 terms term NOUN ffhd-108 21 40 of of ADP ffhd-108 21 41 the the DET ffhd-108 21 42 creative creative ADJ ffhd-108 21 43 commons common NOUN ffhd-108 21 44 attribution attribution NOUN ffhd-108 21 45 4.0 4.0 NUM ffhd-108 21 46 international international ADJ ffhd-108 21 47 license license NOUN ffhd-108 21 48 . . PUNCT ffhd-108 22 1 this this DET ffhd-108 22 2 license license NOUN ffhd-108 22 3 permits permit VERB ffhd-108 22 4 unrestricted unrestricted ADJ ffhd-108 22 5 use use NOUN ffhd-108 22 6 , , PUNCT ffhd-108 22 7 distribution distribution NOUN ffhd-108 22 8 , , PUNCT ffhd-108 22 9 and and CCONJ ffhd-108 22 10 reproduction reproduction NOUN ffhd-108 22 11 in in ADP ffhd-108 22 12 any any DET ffhd-108 22 13 medium medium NOUN ffhd-108 22 14 , , PUNCT ffhd-108 22 15 including include VERB ffhd-108 22 16 commercial commercial ADJ ffhd-108 22 17 use use NOUN ffhd-108 22 18 , , PUNCT ffhd-108 22 19 provided provide VERB ffhd-108 22 20 the the DET ffhd-108 22 21 original original ADJ ffhd-108 22 22 author(s author(s NOUN ffhd-108 22 23 ) ) PUNCT ffhd-108 22 24 and and CCONJ ffhd-108 22 25 source source NOUN ffhd-108 22 26 are be AUX ffhd-108 22 27 properly properly ADV ffhd-108 22 28 credited credit VERB ffhd-108 22 29 . . PUNCT ffhd-108 23 1 authors author NOUN ffhd-108 23 2 may may AUX ffhd-108 23 3 post post VERB ffhd-108 23 4 and and CCONJ ffhd-108 23 5 share share VERB ffhd-108 23 6 their their PRON ffhd-108 23 7 published publish VERB ffhd-108 23 8 work work NOUN ffhd-108 23 9 freely freely ADV ffhd-108 23 10 , , PUNCT ffhd-108 23 11 provided provide VERB ffhd-108 23 12 that that SCONJ ffhd-108 23 13 the the DET ffhd-108 23 14 original original ADJ ffhd-108 23 15 publication publication NOUN ffhd-108 23 16 in in ADP ffhd-108 23 17 this this DET ffhd-108 23 18 journal journal NOUN ffhd-108 23 19 is be AUX ffhd-108 23 20 acknowledged acknowledge VERB ffhd-108 23 21 . . PUNCT ffhd-108 24 1 by by ADP ffhd-108 24 2 submitting submit VERB ffhd-108 24 3 to to ADP ffhd-108 24 4 this this DET ffhd-108 24 5 journal journal NOUN ffhd-108 24 6 , , PUNCT ffhd-108 24 7 authors author NOUN ffhd-108 24 8 confirm confirm VERB ffhd-108 24 9 that that SCONJ ffhd-108 24 10 their their PRON ffhd-108 24 11 manuscripts manuscript NOUN ffhd-108 24 12 are be AUX ffhd-108 24 13 original original ADJ ffhd-108 24 14 , , PUNCT ffhd-108 24 15 not not PART ffhd-108 24 16 under under ADP ffhd-108 24 17 consideration consideration NOUN ffhd-108 24 18 elsewhere elsewhere ADV ffhd-108 24 19 , , PUNCT ffhd-108 24 20 and and CCONJ ffhd-108 24 21 that that SCONJ ffhd-108 24 22 they they PRON ffhd-108 24 23 hold hold VERB ffhd-108 24 24 the the DET ffhd-108 24 25 necessary necessary ADJ ffhd-108 24 26 rights right NOUN ffhd-108 24 27 to to PART ffhd-108 24 28 grant grant VERB ffhd-108 24 29 this this DET ffhd-108 24 30 license license NOUN ffhd-108 24 31 . . PUNCT ffhd-108 25 1 the the DET ffhd-108 25 2 functional functional ADJ ffhd-108 25 3 food food NOUN ffhd-108 25 4 center center NOUN ffhd-108 25 5 encourages encourage VERB ffhd-108 25 6 open open ADJ ffhd-108 25 7 scientific scientific ADJ ffhd-108 25 8 exchange exchange NOUN ffhd-108 25 9 and and CCONJ ffhd-108 25 10 allows allow VERB ffhd-108 25 11 derivative derivative ADJ ffhd-108 25 12 and and CCONJ ffhd-108 25 13 extended extended ADJ ffhd-108 25 14 works work NOUN ffhd-108 25 15 , , PUNCT ffhd-108 25 16 provided provide VERB ffhd-108 25 17 attribution attribution NOUN ffhd-108 25 18 to to ADP ffhd-108 25 19 the the DET ffhd-108 25 20 original original ADJ ffhd-108 25 21 publication publication NOUN ffhd-108 25 22 is be AUX ffhd-108 25 23 maintained maintain VERB ffhd-108 25 24 . . PUNCT ffhd-108 26 1 about about ADP ffhd-108 26 2 the the DET ffhd-108 26 3 journal journal NOUN ffhd-108 26 4             SPACE ffhd-108 26 5 editing edit VERB ffhd-108 26 6 services service NOUN ffhd-108 26 7             SPACE ffhd-108 26 8 graphical graphical ADJ ffhd-108 26 9 abstract abstract ADJ ffhd-108 26 10             SPACE ffhd-108 26 11 journal journal NOUN ffhd-108 26 12 insights insight NOUN ffhd-108 26 13                 SPACE ffhd-108 26 14 submissions submission NOUN ffhd-108 26 15                 SPACE ffhd-108 26 16 editorial editorial ADJ ffhd-108 26 17 team team NOUN ffhd-108 26 18                 SPACE ffhd-108 26 19 privacy privacy NOUN ffhd-108 26 20 statement statement NOUN ffhd-108 26 21                 SPACE ffhd-108 26 22 contact contact NOUN ffhd-108 26 23                 SPACE ffhd-108 26 24 current current ADJ ffhd-108 26 25                 SPACE ffhd-108 26 26 archives archive NOUN ffhd-108 26 27     SPACE ffhd-108 26 28 open open ADJ ffhd-108 26 29 journal journal NOUN ffhd-108 26 30 systems system NOUN ffhd-108 26 31 hosting host VERB ffhd-108 26 32 and and CCONJ ffhd-108 26 33 support support NOUN ffhd-108 26 34 by by ADP ffhd-108 26 35 : : PUNCT ffhd-108 26 36 openjournalsystems.com openjournalsystems.com X