id sid tid token lemma pos ffhd-56 1 1 inhibition inhibition NOUN ffhd-56 1 2 of of ADP ffhd-56 1 3 sirt1 sirt1 NOUN ffhd-56 1 4 transcription transcription NOUN ffhd-56 1 5 in in ADP ffhd-56 1 6 resveratrol resveratrol NOUN ffhd-56 1 7 - - PUNCT ffhd-56 1 8 differentiated differentiate VERB ffhd-56 1 9 medulloblastoma medulloblastoma NOUN ffhd-56 1 10 cells cell NOUN ffhd-56 1 11 | | ADV ffhd-56 1 12 functional functional ADJ ffhd-56 1 13 foods food NOUN ffhd-56 1 14 in in ADP ffhd-56 1 15 health health NOUN ffhd-56 1 16 and and CCONJ ffhd-56 1 17 disease disease PROPN ffhd-56 1 18 online online PROPN ffhd-56 1 19 issn issn PROPN ffhd-56 1 20 : : PUNCT ffhd-56 1 21 2160 2160 NUM ffhd-56 1 22 - - SYM ffhd-56 1 23 3855 3855 NUM ffhd-56 1 24 ; ; PUNCT ffhd-56 1 25 print print NOUN ffhd-56 1 26 issn issn PROPN ffhd-56 1 27 : : PUNCT ffhd-56 1 28 2378 2378 NUM ffhd-56 1 29 - - SYM ffhd-56 1 30 7007 7007 NUM ffhd-56 1 31 skip skip NOUN ffhd-56 1 32 to to ADP ffhd-56 1 33 main main ADJ ffhd-56 1 34 content content NOUN ffhd-56 1 35 skip skip ADJ ffhd-56 1 36 to to ADP ffhd-56 1 37 main main ADJ ffhd-56 1 38 navigation navigation NOUN ffhd-56 1 39 menu menu NOUN ffhd-56 1 40 skip skip VERB ffhd-56 1 41 to to PART ffhd-56 1 42 site site VERB ffhd-56 1 43 footer footer ADJ ffhd-56 1 44 open open ADJ ffhd-56 1 45 menu menu NOUN ffhd-56 1 46 functional functional ADJ ffhd-56 1 47 foods food NOUN ffhd-56 1 48 in in ADP ffhd-56 1 49 health health NOUN ffhd-56 1 50 and and CCONJ ffhd-56 1 51 disease disease PROPN ffhd-56 1 52 online online PROPN ffhd-56 1 53 issn issn PROPN ffhd-56 1 54 : : PUNCT ffhd-56 1 55 2160 2160 NUM ffhd-56 1 56 - - SYM ffhd-56 1 57 3855 3855 NUM ffhd-56 1 58 ; ; PUNCT ffhd-56 1 59 print print NOUN ffhd-56 1 60 issn issn PROPN ffhd-56 1 61 : : PUNCT ffhd-56 1 62 2378 2378 NUM ffhd-56 1 63 - - SYM ffhd-56 1 64 7007 7007 NUM ffhd-56 1 65 home home NOUN ffhd-56 1 66 food food NOUN ffhd-56 1 67 science science NOUN ffhd-56 1 68 publisher publisher NOUN ffhd-56 1 69 functional functional ADJ ffhd-56 1 70 food food NOUN ffhd-56 1 71 center center NOUN ffhd-56 1 72 current current ADJ ffhd-56 1 73 archives archive NOUN ffhd-56 1 74 about about ADP ffhd-56 1 75 about about ADP ffhd-56 1 76 the the DET ffhd-56 1 77 journal journal NOUN ffhd-56 1 78 aims aim VERB ffhd-56 1 79 and and CCONJ ffhd-56 1 80 scope scope NOUN ffhd-56 1 81 contact contact NOUN ffhd-56 1 82 editing edit VERB ffhd-56 1 83 services service NOUN ffhd-56 1 84 editorial editorial ADJ ffhd-56 1 85 team team NOUN ffhd-56 1 86 express express VERB ffhd-56 1 87 peer peer NOUN ffhd-56 1 88 review review NOUN ffhd-56 1 89 graphical graphical ADJ ffhd-56 1 90 abstract abstract ADJ ffhd-56 1 91 journal journal NOUN ffhd-56 1 92 insights insight VERB ffhd-56 1 93 privacy privacy NOUN ffhd-56 1 94 statement statement NOUN ffhd-56 1 95 submissions submission NOUN ffhd-56 1 96 announcements announcement NOUN ffhd-56 1 97 search search NOUN ffhd-56 1 98 search search NOUN ffhd-56 1 99 register register NOUN ffhd-56 1 100 login login NOUN ffhd-56 1 101 home home NOUN ffhd-56 1 102 / / SYM ffhd-56 1 103 archives archive NOUN ffhd-56 1 104 / / SYM ffhd-56 1 105 vol vol NOUN ffhd-56 1 106 . . PROPN ffhd-56 2 1 3 3 NUM ffhd-56 3 1 no no NOUN ffhd-56 3 2 . . NOUN ffhd-56 3 3 5 5 NUM ffhd-56 3 4 ( ( PUNCT ffhd-56 3 5 2013 2013 NUM ffhd-56 3 6 ): ): PUNCT ffhd-56 3 7 may may PROPN ffhd-56 3 8 2013 2013 NUM ffhd-56 3 9 / / SYM ffhd-56 3 10 research research NOUN ffhd-56 3 11 articles article NOUN ffhd-56 3 12 inhibition inhibition NOUN ffhd-56 3 13 of of ADP ffhd-56 3 14 sirt1 sirt1 NOUN ffhd-56 3 15 transcription transcription NOUN ffhd-56 3 16 in in ADP ffhd-56 3 17 resveratrol resveratrol NOUN ffhd-56 3 18 - - PUNCT ffhd-56 3 19 differentiated differentiate VERB ffhd-56 3 20 medulloblastoma medulloblastoma NOUN ffhd-56 3 21 cells cell NOUN ffhd-56 3 22 authors author NOUN ffhd-56 3 23 jing je VERB ffhd-56 3 24 - - PUNCT ffhd-56 3 25 xin xin PROPN ffhd-56 3 26 ma ma PROPN ffhd-56 3 27 liaoning liaoning PROPN ffhd-56 3 28 laboratory laboratory PROPN ffhd-56 3 29 of of ADP ffhd-56 3 30 cancer cancer NOUN ffhd-56 3 31 genetics genetic NOUN ffhd-56 3 32 and and CCONJ ffhd-56 3 33 epigenetics epigenetic NOUN ffhd-56 3 34 and and CCONJ ffhd-56 3 35 department department NOUN ffhd-56 3 36 of of ADP ffhd-56 3 37 cell cell NOUN ffhd-56 3 38 biology biology NOUN ffhd-56 3 39 , , PUNCT ffhd-56 3 40 dalian dalian PROPN ffhd-56 3 41 medical medical PROPN ffhd-56 3 42 university university PROPN ffhd-56 3 43 , , PUNCT ffhd-56 3 44 dalian dalian PROPN ffhd-56 3 45 116044 116044 NUM ffhd-56 3 46 hong hong PROPN ffhd-56 3 47 li li PROPN ffhd-56 3 48 liaoning liaoning PROPN ffhd-56 3 49 laboratory laboratory PROPN ffhd-56 3 50 of of ADP ffhd-56 3 51 cancer cancer NOUN ffhd-56 3 52 genetics genetic NOUN ffhd-56 3 53 and and CCONJ ffhd-56 3 54 epigenetics epigenetic NOUN ffhd-56 3 55 and and CCONJ ffhd-56 3 56 department department NOUN ffhd-56 3 57 of of ADP ffhd-56 3 58 cell cell NOUN ffhd-56 3 59 biology biology NOUN ffhd-56 3 60 , , PUNCT ffhd-56 3 61 dalian dalian PROPN ffhd-56 3 62 medical medical PROPN ffhd-56 3 63 university university PROPN ffhd-56 3 64 , , PUNCT ffhd-56 3 65 dalian dalian PROPN ffhd-56 3 66 116044 116044 NUM ffhd-56 3 67 xiao xiao PROPN ffhd-56 3 68 - - PUNCT ffhd-56 3 69 xin xin PROPN ffhd-56 3 70 cheng cheng PROPN ffhd-56 3 71 liaoning liaoning PROPN ffhd-56 3 72 laboratory laboratory PROPN ffhd-56 3 73 of of ADP ffhd-56 3 74 cancer cancer NOUN ffhd-56 3 75 genetics genetic NOUN ffhd-56 3 76 and and CCONJ ffhd-56 3 77 epigenetics epigenetic NOUN ffhd-56 3 78 and and CCONJ ffhd-56 3 79 department department NOUN ffhd-56 3 80 of of ADP ffhd-56 3 81 cell cell NOUN ffhd-56 3 82 biology biology NOUN ffhd-56 3 83 , , PUNCT ffhd-56 3 84 dalian dalian PROPN ffhd-56 3 85 medical medical PROPN ffhd-56 3 86 university university PROPN ffhd-56 3 87 , , PUNCT ffhd-56 3 88 dalian dalian PROPN ffhd-56 3 89 116044 116044 NUM ffhd-56 3 90 mo mo PROPN ffhd-56 3 91 - - PUNCT ffhd-56 3 92 li li PROPN ffhd-56 3 93 wu wu PROPN ffhd-56 3 94 liaoning liaoning PROPN ffhd-56 3 95 laboratory laboratory PROPN ffhd-56 3 96 of of ADP ffhd-56 3 97 cancer cancer NOUN ffhd-56 3 98 genetics genetic NOUN ffhd-56 3 99 and and CCONJ ffhd-56 3 100 epigenetics epigenetic NOUN ffhd-56 3 101 and and CCONJ ffhd-56 3 102 department department NOUN ffhd-56 3 103 of of ADP ffhd-56 3 104 cell cell NOUN ffhd-56 3 105 biology biology NOUN ffhd-56 3 106 , , PUNCT ffhd-56 3 107 dalian dalian PROPN ffhd-56 3 108 medical medical PROPN ffhd-56 3 109 university university PROPN ffhd-56 3 110 , , PUNCT ffhd-56 3 111 dalian dalian PROPN ffhd-56 3 112 116044 116044 NUM ffhd-56 3 113 li li PROPN ffhd-56 3 114 - - PROPN ffhd-56 3 115 jun jun PROPN ffhd-56 3 116 yu yu PROPN ffhd-56 3 117 liaoning liaoning PROPN ffhd-56 3 118 laboratory laboratory PROPN ffhd-56 3 119 of of ADP ffhd-56 3 120 cancer cancer NOUN ffhd-56 3 121 genetics genetic NOUN ffhd-56 3 122 and and CCONJ ffhd-56 3 123 epigenetics epigenetic NOUN ffhd-56 3 124 and and CCONJ ffhd-56 3 125 department department NOUN ffhd-56 3 126 of of ADP ffhd-56 3 127 cell cell NOUN ffhd-56 3 128 biology biology NOUN ffhd-56 3 129 , , PUNCT ffhd-56 3 130 dalian dalian PROPN ffhd-56 3 131 medical medical PROPN ffhd-56 3 132 university university PROPN ffhd-56 3 133 , , PUNCT ffhd-56 3 134 dalian dalian PROPN ffhd-56 3 135 116044 116044 NUM ffhd-56 3 136 qing qing NOUN ffhd-56 3 137 - - PUNCT ffhd-56 3 138 you you PRON ffhd-56 3 139 kong kong PROPN ffhd-56 3 140 liaoning liaoning PROPN ffhd-56 3 141 laboratory laboratory PROPN ffhd-56 3 142 of of ADP ffhd-56 3 143 cancer cancer NOUN ffhd-56 3 144 genetics genetic NOUN ffhd-56 3 145 and and CCONJ ffhd-56 3 146 epigenetics epigenetic NOUN ffhd-56 3 147 and and CCONJ ffhd-56 3 148 department department NOUN ffhd-56 3 149 of of ADP ffhd-56 3 150 cell cell NOUN ffhd-56 3 151 biology biology NOUN ffhd-56 3 152 , , PUNCT ffhd-56 3 153 dalian dalian PROPN ffhd-56 3 154 medical medical PROPN ffhd-56 3 155 university university PROPN ffhd-56 3 156 , , PUNCT ffhd-56 3 157 dalian dalian PROPN ffhd-56 3 158 116044 116044 NUM ffhd-56 3 159 ming ming PROPN ffhd-56 3 160 liu liu PROPN ffhd-56 3 161 liaoning liaoning PROPN ffhd-56 3 162 laboratory laboratory PROPN ffhd-56 3 163 of of ADP ffhd-56 3 164 cancer cancer NOUN ffhd-56 3 165 genetics genetic NOUN ffhd-56 3 166 and and CCONJ ffhd-56 3 167 epigenetics epigenetic NOUN ffhd-56 3 168 and and CCONJ ffhd-56 3 169 department department NOUN ffhd-56 3 170 of of ADP ffhd-56 3 171 cell cell NOUN ffhd-56 3 172 biology biology NOUN ffhd-56 3 173 , , PUNCT ffhd-56 3 174 dalian dalian PROPN ffhd-56 3 175 medical medical PROPN ffhd-56 3 176 university university PROPN ffhd-56 3 177 , , PUNCT ffhd-56 3 178 dalian dalian PROPN ffhd-56 3 179 116044 116044 NUM ffhd-56 3 180 jia jia PROPN ffhd-56 3 181 liu liu PROPN ffhd-56 3 182 liaoning liaoning PROPN ffhd-56 3 183 laboratory laboratory PROPN ffhd-56 3 184 of of ADP ffhd-56 3 185 cancer cancer NOUN ffhd-56 3 186 genetics genetic NOUN ffhd-56 3 187 and and CCONJ ffhd-56 3 188 epigenetics epigenetic NOUN ffhd-56 3 189 and and CCONJ ffhd-56 3 190 department department NOUN ffhd-56 3 191 of of ADP ffhd-56 3 192 cell cell NOUN ffhd-56 3 193 biology biology NOUN ffhd-56 3 194 , , PUNCT ffhd-56 3 195 dalian dalian PROPN ffhd-56 3 196 medical medical PROPN ffhd-56 3 197 university university PROPN ffhd-56 3 198 , , PUNCT ffhd-56 3 199 dalian dalian PROPN ffhd-56 3 200 116044 116044 NUM ffhd-56 3 201 doi doi NOUN ffhd-56 3 202 : : PUNCT ffhd-56 3 203 https://doi.org/10.31989/ffhd.v3i5.56 https://doi.org/10.31989/ffhd.v3i5.56 VERB ffhd-56 3 204 abstract abstract ADJ ffhd-56 3 205 backgrounds background NOUN ffhd-56 3 206 : : PUNCT ffhd-56 3 207 medulloblastoma medulloblastoma ADJ ffhd-56 3 208 ( ( PUNCT ffhd-56 3 209 mb mb NOUN ffhd-56 3 210 ) ) PUNCT ffhd-56 3 211 is be AUX ffhd-56 3 212 the the DET ffhd-56 3 213 commonest commonest NOUN ffhd-56 3 214 brain brain NOUN ffhd-56 3 215 malignancy malignancy NOUN ffhd-56 3 216 in in ADP ffhd-56 3 217 childhood childhood NOUN ffhd-56 3 218 with with ADP ffhd-56 3 219 poor poor ADJ ffhd-56 3 220 prognosis prognosis NOUN ffhd-56 3 221 , , PUNCT ffhd-56 3 222 because because SCONJ ffhd-56 3 223 of of ADP ffhd-56 3 224 its its PRON ffhd-56 3 225 rapid rapid ADJ ffhd-56 3 226 aggressive aggressive ADJ ffhd-56 3 227 growth growth NOUN ffhd-56 3 228 and and CCONJ ffhd-56 3 229 frequent frequent ADJ ffhd-56 3 230 occurrence occurrence NOUN ffhd-56 3 231 . . PUNCT ffhd-56 4 1 the the DET ffhd-56 4 2 current current ADJ ffhd-56 4 3 chemotherapeutic chemotherapeutic ADJ ffhd-56 4 4 regimens regimen NOUN ffhd-56 4 5 for for ADP ffhd-56 4 6 medulloblastoma medulloblastoma ADJ ffhd-56 4 7 patients patient NOUN ffhd-56 4 8 involve involve VERB ffhd-56 4 9 a a DET ffhd-56 4 10 combination combination NOUN ffhd-56 4 11 of of ADP ffhd-56 4 12 lomustine lomustine NOUN ffhd-56 4 13 , , PUNCT ffhd-56 4 14 cisplatin cisplatin NOUN ffhd-56 4 15 , , PUNCT ffhd-56 4 16 carboplatin carboplatin NOUN ffhd-56 4 17 , , PUNCT ffhd-56 4 18 vincristine vincristine NOUN ffhd-56 4 19 or or CCONJ ffhd-56 4 20 cyclophosphamide cyclophosphamide NOUN ffhd-56 4 21 , , PUNCT ffhd-56 4 22 which which PRON ffhd-56 4 23 have have VERB ffhd-56 4 24 distinct distinct ADJ ffhd-56 4 25 shortand shortand NOUN ffhd-56 4 26 long long ADJ ffhd-56 4 27 - - PUNCT ffhd-56 4 28 term term NOUN ffhd-56 4 29 side side NOUN ffhd-56 4 30 - - PUNCT ffhd-56 4 31 effects effect NOUN ffhd-56 4 32 . . PUNCT ffhd-56 5 1 it it PRON ffhd-56 5 2 is be AUX ffhd-56 5 3 therefore therefore ADV ffhd-56 5 4 in in ADP ffhd-56 5 5 urgent urgent ADJ ffhd-56 5 6 need need NOUN ffhd-56 5 7 to to PART ffhd-56 5 8 explore explore VERB ffhd-56 5 9 safer safe ADJ ffhd-56 5 10 and and CCONJ ffhd-56 5 11 more more ADV ffhd-56 5 12 effective effective ADJ ffhd-56 5 13 adjuvant adjuvant ADJ ffhd-56 5 14 approach(s approach(s PROPN ffhd-56 5 15 ) ) PUNCT ffhd-56 5 16 . . PUNCT ffhd-56 6 1 resveratrol resveratrol NOUN ffhd-56 6 2 , , PUNCT ffhd-56 6 3 a a DET ffhd-56 6 4 polyphenol polyphenol NOUN ffhd-56 6 5 rich rich ADJ ffhd-56 6 6 in in ADP ffhd-56 6 7 numerous numerous ADJ ffhd-56 6 8 plants plant NOUN ffhd-56 6 9 , , PUNCT ffhd-56 6 10 has have VERB ffhd-56 6 11 multiple multiple ADJ ffhd-56 6 12 biological biological ADJ ffhd-56 6 13 activities activity NOUN ffhd-56 6 14 including include VERB ffhd-56 6 15 anticancer anticancer NOUN ffhd-56 6 16 effects effect NOUN ffhd-56 6 17 . . PUNCT ffhd-56 7 1 our our PRON ffhd-56 7 2 previous previous ADJ ffhd-56 7 3 data datum NOUN ffhd-56 7 4 confirmed confirm VERB ffhd-56 7 5 that that SCONJ ffhd-56 7 6 resveratrol resveratrol NOUN ffhd-56 7 7     SPACE ffhd-56 7 8 inhibited inhibit VERB ffhd-56 7 9 proliferation proliferation NOUN ffhd-56 7 10 and and CCONJ ffhd-56 7 11 induced induced ADJ ffhd-56 7 12 differentiation differentiation NOUN ffhd-56 7 13 and and CCONJ ffhd-56 7 14 apoptosis apoptosis NOUN ffhd-56 7 15 of of ADP ffhd-56 7 16 medulloblastoma medulloblastoma ADJ ffhd-56 7 17 cells cell NOUN ffhd-56 7 18 . . PUNCT ffhd-56 8 1 sirt1 sirt1 NOUN ffhd-56 8 2 is be AUX ffhd-56 8 3 a a DET ffhd-56 8 4 deacetylase deacetylase NOUN ffhd-56 8 5 of of ADP ffhd-56 8 6 class class NOUN ffhd-56 8 7 iii iii PROPN ffhd-56 8 8 hdacs hdac NOUN ffhd-56 8 9 and and CCONJ ffhd-56 8 10 the the DET ffhd-56 8 11 supposed suppose VERB ffhd-56 8 12 molecular molecular ADJ ffhd-56 8 13 effecter effecter NOUN ffhd-56 8 14 of of ADP ffhd-56 8 15 resveratrol resveratrol NOUN ffhd-56 8 16 . . PUNCT ffhd-56 9 1 sirt1 sirt1 NOUN ffhd-56 9 2 involves involve VERB ffhd-56 9 3 in in ADP ffhd-56 9 4 aging age VERB ffhd-56 9 5 prevention prevention NOUN ffhd-56 9 6 and and CCONJ ffhd-56 9 7 cancer cancer NOUN ffhd-56 9 8 formation formation NOUN ffhd-56 9 9 in in ADP ffhd-56 9 10 a a DET ffhd-56 9 11 cell cell NOUN ffhd-56 9 12 - - PUNCT ffhd-56 9 13 context context NOUN ffhd-56 9 14 specific specific ADJ ffhd-56 9 15 manner manner NOUN ffhd-56 9 16 . . PUNCT ffhd-56 9 17     SPACE ffhd-56 10 1 nevertheless nevertheless ADV ffhd-56 10 2 , , PUNCT ffhd-56 10 3 the the DET ffhd-56 10 4 datum datum NOUN ffhd-56 10 5 concerning concern VERB ffhd-56 10 6 the the DET ffhd-56 10 7 role(s role(s PROPN ffhd-56 10 8 ) ) PUNCT ffhd-56 10 9 of of ADP ffhd-56 10 10 sirt1 sirt1 NOUN ffhd-56 10 11 in in ADP ffhd-56 10 12 formation formation NOUN ffhd-56 10 13 and and CCONJ ffhd-56 10 14 prognosis prognosis NOUN ffhd-56 10 15 of of ADP ffhd-56 10 16 medulloblastoma medulloblastoma NOUN ffhd-56 10 17 is be AUX ffhd-56 10 18 still still ADV ffhd-56 10 19 missing miss VERB ffhd-56 10 20 . . PUNCT ffhd-56 11 1 objective objective NOUN ffhd-56 11 2 : : PUNCT ffhd-56 11 3 the the DET ffhd-56 11 4 present present ADJ ffhd-56 11 5 study study NOUN ffhd-56 11 6 aimed aim VERB ffhd-56 11 7 to to PART ffhd-56 11 8 address address VERB ffhd-56 11 9 the the DET ffhd-56 11 10 expression expression NOUN ffhd-56 11 11 patterna patterna NOUN ffhd-56 11 12 of of ADP ffhd-56 11 13 sirt1 sirt1 NOUN ffhd-56 11 14 in in ADP ffhd-56 11 15 medulloblastoma medulloblastoma ADJ ffhd-56 11 16 tissues tissue NOUN ffhd-56 11 17 and and CCONJ ffhd-56 11 18 non non ADJ ffhd-56 11 19 - - ADJ ffhd-56 11 20 cancerous cancerous ADJ ffhd-56 11 21 counterparts counterpart NOUN ffhd-56 11 22 and and CCONJ ffhd-56 11 23 to to PART ffhd-56 11 24 explore explore VERB ffhd-56 11 25 whether whether SCONJ ffhd-56 11 26 resveratrol resveratrol NOUN ffhd-56 11 27 exerts exert VERB ffhd-56 11 28 its its PRON ffhd-56 11 29 anti anti ADJ ffhd-56 11 30 - - ADJ ffhd-56 11 31 medulloblastoma medulloblastoma ADJ ffhd-56 11 32 effects effect NOUN ffhd-56 11 33 via via ADP ffhd-56 11 34 regulating regulate VERB ffhd-56 11 35 sirt1 sirt1 NOUN ffhd-56 11 36 expression expression NOUN ffhd-56 11 37 and and CCONJ ffhd-56 11 38 bioactivity bioactivity NOUN ffhd-56 11 39 . . PUNCT ffhd-56 12 1 methods method NOUN ffhd-56 12 2 : : PUNCT ffhd-56 12 3 the the DET ffhd-56 12 4 expression expression NOUN ffhd-56 12 5 of of ADP ffhd-56 12 6 sirt1 sirt1 NOUN ffhd-56 12 7 in in ADP ffhd-56 12 8 medulloblastoma medulloblastoma NOUN ffhd-56 12 9 and and CCONJ ffhd-56 12 10 non non ADJ ffhd-56 12 11 - - ADJ ffhd-56 12 12 cancerous cancerous ADJ ffhd-56 12 13 counterparts counterpart NOUN ffhd-56 12 14 was be AUX ffhd-56 12 15 elucidated elucidate VERB ffhd-56 12 16 by by ADP ffhd-56 12 17 immunohistochemical immunohistochemical ADJ ffhd-56 12 18 ataining ataining NOUN ffhd-56 12 19 ( ( PUNCT ffhd-56 12 20 ihc ihc PROPN ffhd-56 12 21 ) ) PUNCT ffhd-56 12 22 . . PUNCT ffhd-56 13 1 to to PART ffhd-56 13 2 clarify clarify VERB ffhd-56 13 3 the the DET ffhd-56 13 4 function function NOUN ffhd-56 13 5 of of ADP ffhd-56 13 6 sirt1 sirt1 NOUN ffhd-56 13 7 in in ADP ffhd-56 13 8 medulloblastomas medulloblastoma NOUN ffhd-56 13 9 , , PUNCT ffhd-56 13 10 sirt1 sirt1 NOUN ffhd-56 13 11 expression expression NOUN ffhd-56 13 12 in in ADP ffhd-56 13 13 uw228 uw228 PROPN ffhd-56 13 14 - - PUNCT ffhd-56 13 15 3 3 NUM ffhd-56 13 16 medulloblastoma medulloblastoma NOUN ffhd-56 13 17 cells cell NOUN ffhd-56 13 18 were be AUX ffhd-56 13 19 suppressed suppress VERB ffhd-56 13 20 by by ADP ffhd-56 13 21 rna rna NOUN ffhd-56 13 22 interference interference NOUN ffhd-56 13 23 ( ( PUNCT ffhd-56 13 24 rnai rnai PROPN ffhd-56 13 25 ) ) PUNCT ffhd-56 13 26 . . PUNCT ffhd-56 14 1 the the DET ffhd-56 14 2 influence influence NOUN ffhd-56 14 3 of of ADP ffhd-56 14 4 resveratrol resveratrol NOUN ffhd-56 14 5 in in ADP ffhd-56 14 6 sirt1 sirt1 NOUN ffhd-56 14 7 expressions expression NOUN ffhd-56 14 8 in in ADP ffhd-56 14 9 uw228 uw228 PROPN ffhd-56 14 10 - - PUNCT ffhd-56 14 11 3 3 NUM ffhd-56 14 12 cells cell NOUN ffhd-56 14 13 was be AUX ffhd-56 14 14 analyzed analyze VERB ffhd-56 14 15 by by ADP ffhd-56 14 16 reverse reverse ADJ ffhd-56 14 17 transcription transcription NOUN ffhd-56 14 18 - - PUNCT ffhd-56 14 19 polymerase polymerase NOUN ffhd-56 14 20 chain chain NOUN ffhd-56 14 21 reaction reaction NOUN ffhd-56 14 22 ( ( PUNCT ffhd-56 14 23 rt rt NOUN ffhd-56 14 24 - - PUNCT ffhd-56 14 25 pcr pcr NOUN ffhd-56 14 26 ) ) PUNCT ffhd-56 14 27 , , PUNCT ffhd-56 14 28     SPACE ffhd-56 14 29 immunocytochemistry immunocytochemistry NOUN ffhd-56 14 30 ( ( PUNCT ffhd-56 14 31 icc icc PROPN ffhd-56 14 32 ) ) PUNCT ffhd-56 14 33 and and CCONJ ffhd-56 14 34 western western ADJ ffhd-56 14 35 blotting blot VERB ffhd-56 14 36 ( ( PUNCT ffhd-56 14 37 wb wb PROPN ffhd-56 14 38 ) ) PUNCT ffhd-56 14 39 . . PUNCT ffhd-56 15 1 the the DET ffhd-56 15 2 catalytic catalytic ADJ ffhd-56 15 3 activity activity NOUN ffhd-56 15 4 of of ADP ffhd-56 15 5 deacetylase deacetylase PROPN ffhd-56 15 6 sirt1 sirt1 PROPN ffhd-56 15 7 was be AUX ffhd-56 15 8 examined examine VERB ffhd-56 15 9 by by ADP ffhd-56 15 10 measuring measure VERB ffhd-56 15 11 the the DET ffhd-56 15 12 acetylation acetylation NOUN ffhd-56 15 13 of of ADP ffhd-56 15 14 the the DET ffhd-56 15 15 main main ADJ ffhd-56 15 16 substrate substrate NOUN ffhd-56 15 17 p53 p53 NOUN ffhd-56 15 18 . . PUNCT ffhd-56 16 1 results result NOUN ffhd-56 16 2 : : PUNCT ffhd-56 16 3 ihc ihc PROPN ffhd-56 16 4 staining staining NOUN ffhd-56 16 5 revealed reveal VERB ffhd-56 16 6 that that SCONJ ffhd-56 16 7 sirt1 sirt1 NOUN ffhd-56 16 8 was be AUX ffhd-56 16 9 expressed express VERB ffhd-56 16 10 in in ADP ffhd-56 16 11 64.17 64.17 NUM ffhd-56 16 12 % % NOUN ffhd-56 16 13 of of ADP ffhd-56 16 14 mb mb ADJ ffhd-56 16 15 tissues tissue NOUN ffhd-56 16 16 , , PUNCT ffhd-56 16 17 which which PRON ffhd-56 16 18 was be AUX ffhd-56 16 19 higher high ADJ ffhd-56 16 20 than than ADP ffhd-56 16 21 that that PRON ffhd-56 16 22 in in ADP ffhd-56 16 23 noncancerous noncancerous ADJ ffhd-56 16 24 cerebellum cerebellum ADJ ffhd-56 16 25 tissues tissue NOUN ffhd-56 16 26 ( ( PUNCT ffhd-56 16 27 14.29 14.29 NUM ffhd-56 16 28 % % NOUN ffhd-56 16 29 ) ) PUNCT ffhd-56 16 30 . . PUNCT ffhd-56 17 1 the the DET ffhd-56 17 2 frequencies frequency NOUN ffhd-56 17 3 of of ADP ffhd-56 17 4 sirt1 sirt1 NOUN ffhd-56 17 5 expression expression NOUN ffhd-56 17 6 in in ADP ffhd-56 17 7 the the DET ffhd-56 17 8 nodular nodular ADJ ffhd-56 17 9 mb mb NOUN ffhd-56 17 10 ( ( PUNCT ffhd-56 17 11 22.22 22.22 NUM ffhd-56 17 12 % % NOUN ffhd-56 17 13 ) ) PUNCT ffhd-56 17 14 with with ADP ffhd-56 17 15 better well ADJ ffhd-56 17 16 prognosis prognosis NOUN ffhd-56 17 17 is be AUX ffhd-56 17 18 lower low ADJ ffhd-56 17 19 than than ADP ffhd-56 17 20 that that PRON ffhd-56 17 21 in in ADP ffhd-56 17 22 anaplastic anaplastic ADJ ffhd-56 17 23 mb mb ADP ffhd-56 17 24 ( ( PUNCT ffhd-56 17 25 79.07 79.07 NUM ffhd-56 17 26 % % NOUN ffhd-56 17 27 ) ) PUNCT ffhd-56 17 28 and and CCONJ ffhd-56 17 29 classic classic ADJ ffhd-56 17 30 mb mb ADP ffhd-56 17 31 ( ( PUNCT ffhd-56 17 32 60.29 60.29 NUM ffhd-56 17 33 % % NOUN ffhd-56 17 34 ; ; PUNCT ffhd-56 17 35 p<0.05 p<0.05 PROPN ffhd-56 17 36 ) ) PUNCT ffhd-56 17 37 . . PUNCT ffhd-56 18 1 the the DET ffhd-56 18 2 proliferation proliferation NOUN ffhd-56 18 3 of of ADP ffhd-56 18 4 uw228 uw228 PROPN ffhd-56 18 5 - - PUNCT ffhd-56 18 6 3 3 NUM ffhd-56 18 7 cells cell NOUN ffhd-56 18 8 was be AUX ffhd-56 18 9 remarkably remarkably ADV ffhd-56 18 10 suppressed suppress VERB ffhd-56 18 11 after after ADP ffhd-56 18 12 being be AUX ffhd-56 18 13 transfected transfecte VERB ffhd-56 18 14 with with ADP ffhd-56 18 15 sirt1 sirt1 PROPN ffhd-56 18 16 sirna sirna PROPN ffhd-56 18 17 , , PUNCT ffhd-56 18 18 accompanied accompany VERB ffhd-56 18 19 with with ADP ffhd-56 18 20 extensive extensive ADJ ffhd-56 18 21 cell cell NOUN ffhd-56 18 22 death death NOUN ffhd-56 18 23 . . PUNCT ffhd-56 19 1 the the DET ffhd-56 19 2 results result NOUN ffhd-56 19 3 of of ADP ffhd-56 19 4 rt rt NOUN ffhd-56 19 5 - - PUNCT ffhd-56 19 6 pcr pcr PROPN ffhd-56 19 7 and and CCONJ ffhd-56 19 8 wb wb PROPN ffhd-56 19 9 showed show VERB ffhd-56 19 10 that that SCONJ ffhd-56 19 11 after after ADP ffhd-56 19 12 48 48 NUM ffhd-56 19 13 hours hour NOUN ffhd-56 19 14 100 100 NUM ffhd-56 19 15 m m NOUN ffhd-56 19 16 resveratrol resveratrol NOUN ffhd-56 19 17 treatment treatment NOUN ffhd-56 19 18 , , PUNCT ffhd-56 19 19 sirt1 sirt1 NOUN ffhd-56 19 20 expression expression NOUN ffhd-56 19 21 in in ADP ffhd-56 19 22 uw228 uw228 PROPN ffhd-56 19 23 - - PUNCT ffhd-56 19 24 3 3 NUM ffhd-56 19 25 cells cell NOUN ffhd-56 19 26 was be AUX ffhd-56 19 27 down down ADV ffhd-56 19 28 - - PUNCT ffhd-56 19 29 regulated regulate VERB ffhd-56 19 30 at at ADP ffhd-56 19 31 both both CCONJ ffhd-56 19 32 transcriptional transcriptional ADJ ffhd-56 19 33 and and CCONJ ffhd-56 19 34 translational translational ADJ ffhd-56 19 35 levels level NOUN ffhd-56 19 36 . . PUNCT ffhd-56 20 1 however however ADV ffhd-56 20 2 , , PUNCT ffhd-56 20 3 resveratrol resveratrol NOUN ffhd-56 20 4 has have VERB ffhd-56 20 5 no no DET ffhd-56 20 6 effect effect NOUN ffhd-56 20 7 on on ADP ffhd-56 20 8 the the DET ffhd-56 20 9 deacetylase deacetylase NOUN ffhd-56 20 10 activity activity NOUN ffhd-56 20 11 of of ADP ffhd-56 20 12 sirt1 sirt1 PROPN ffhd-56 20 13 . . PUNCT ffhd-56 20 14 conclusion conclusion NOUN ffhd-56 20 15 : : PUNCT ffhd-56 20 16 the the DET ffhd-56 20 17 above above ADJ ffhd-56 20 18 findings finding NOUN ffhd-56 20 19 suggested suggest VERB ffhd-56 20 20 that that SCONJ ffhd-56 20 21 sirt1 sirt1 NOUN ffhd-56 20 22 expression expression NOUN ffhd-56 20 23 is be AUX ffhd-56 20 24 corrected correct VERB ffhd-56 20 25 with with ADP ffhd-56 20 26 the the DET ffhd-56 20 27 formation formation NOUN ffhd-56 20 28 and and CCONJ ffhd-56 20 29 prognosis prognosis NOUN ffhd-56 20 30 of of ADP ffhd-56 20 31 human human ADJ ffhd-56 20 32 mb mb PROPN ffhd-56 20 33 . . PUNCT ffhd-56 21 1 resveratrol resveratrol NOUN ffhd-56 21 2 influences influence VERB ffhd-56 21 3 sirt1 sirt1 NOUN ffhd-56 21 4 functioning function VERB ffhd-56 21 5 in in ADP ffhd-56 21 6 human human ADJ ffhd-56 21 7 mb mb NOUN ffhd-56 21 8 cells cell NOUN ffhd-56 21 9 through through ADP ffhd-56 21 10 inhibiting inhibit VERB ffhd-56 21 11 sirt1 sirt1 NOUN ffhd-56 21 12 expression expression NOUN ffhd-56 21 13 rather rather ADV ffhd-56 21 14 than than ADP ffhd-56 21 15 modulating modulate VERB ffhd-56 21 16 its its PRON ffhd-56 21 17 acetylation acetylation NOUN ffhd-56 21 18 activity activity NOUN ffhd-56 21 19 . . PUNCT ffhd-56 22 1 keywords keyword NOUN ffhd-56 22 2 : : PUNCT ffhd-56 22 3 resveratrol resveratrol NOUN ffhd-56 22 4 , , PUNCT ffhd-56 22 5 sirt1 sirt1 NOUN ffhd-56 22 6 , , PUNCT ffhd-56 22 7 rna rna NOUN ffhd-56 22 8 interference interference NOUN ffhd-56 22 9 , , PUNCT ffhd-56 22 10 deacetylase deacetylase NOUN ffhd-56 22 11 , , PUNCT ffhd-56 22 12 medulloblastoma medulloblastoma NOUN ffhd-56 22 13 downloads download NOUN ffhd-56 23 1 [ [ X ffhd-56 23 2 abstract abstract X ffhd-56 23 3 ] ] X ffhd-56 24 1 [ [ X ffhd-56 24 2 full full ADJ ffhd-56 24 3 article article NOUN ffhd-56 24 4 ] ] PUNCT ffhd-56 24 5 published publish VERB ffhd-56 24 6 2013 2013 NUM ffhd-56 24 7 - - SYM ffhd-56 24 8 05 05 NUM ffhd-56 24 9 - - PUNCT ffhd-56 24 10 31 31 NUM ffhd-56 24 11 issue issue NOUN ffhd-56 24 12 vol vol NOUN ffhd-56 24 13 . . PROPN ffhd-56 24 14 3 3 NUM ffhd-56 25 1 no no NOUN ffhd-56 25 2 . . NOUN ffhd-56 25 3 5 5 NUM ffhd-56 25 4 ( ( PUNCT ffhd-56 25 5 2013 2013 NUM ffhd-56 25 6 ): ): PUNCT ffhd-56 25 7 may may AUX ffhd-56 25 8 2013 2013 NUM ffhd-56 25 9 section section NOUN ffhd-56 25 10 research research NOUN ffhd-56 25 11 articles article NOUN ffhd-56 25 12 license license NOUN ffhd-56 25 13 authors author NOUN ffhd-56 25 14 retain retain VERB ffhd-56 25 15 the the DET ffhd-56 25 16 copyright copyright NOUN ffhd-56 25 17 of of ADP ffhd-56 25 18 their their PRON ffhd-56 25 19 articles article NOUN ffhd-56 25 20 and and CCONJ ffhd-56 25 21 grant grant VERB ffhd-56 25 22 the the DET ffhd-56 25 23 functional functional ADJ ffhd-56 25 24 food food NOUN ffhd-56 25 25 center center NOUN ffhd-56 25 26 ( ( PUNCT ffhd-56 25 27 ffc ffc NOUN ffhd-56 25 28 ) ) PUNCT ffhd-56 25 29 and and CCONJ ffhd-56 25 30 its its PRON ffhd-56 25 31 journals journal NOUN ffhd-56 25 32 the the DET ffhd-56 25 33 right right NOUN ffhd-56 25 34 of of ADP ffhd-56 25 35 first first ADJ ffhd-56 25 36 publication publication NOUN ffhd-56 25 37 under under ADP ffhd-56 25 38 the the DET ffhd-56 25 39 terms term NOUN ffhd-56 25 40 of of ADP ffhd-56 25 41 the the DET ffhd-56 25 42 creative creative ADJ ffhd-56 25 43 commons common NOUN ffhd-56 25 44 attribution attribution NOUN ffhd-56 25 45 4.0 4.0 NUM ffhd-56 25 46 international international ADJ ffhd-56 25 47 license license NOUN ffhd-56 25 48 . . PUNCT ffhd-56 26 1 this this DET ffhd-56 26 2 license license NOUN ffhd-56 26 3 permits permit VERB ffhd-56 26 4 unrestricted unrestricted ADJ ffhd-56 26 5 use use NOUN ffhd-56 26 6 , , PUNCT ffhd-56 26 7 distribution distribution NOUN ffhd-56 26 8 , , PUNCT ffhd-56 26 9 and and CCONJ ffhd-56 26 10 reproduction reproduction NOUN ffhd-56 26 11 in in ADP ffhd-56 26 12 any any DET ffhd-56 26 13 medium medium NOUN ffhd-56 26 14 , , PUNCT ffhd-56 26 15 including include VERB ffhd-56 26 16 commercial commercial ADJ ffhd-56 26 17 use use NOUN ffhd-56 26 18 , , PUNCT ffhd-56 26 19 provided provide VERB ffhd-56 26 20 the the DET ffhd-56 26 21 original original ADJ ffhd-56 26 22 author(s author(s NOUN ffhd-56 26 23 ) ) PUNCT ffhd-56 26 24 and and CCONJ ffhd-56 26 25 source source NOUN ffhd-56 26 26 are be AUX ffhd-56 26 27 properly properly ADV ffhd-56 26 28 credited credit VERB ffhd-56 26 29 . . PUNCT ffhd-56 27 1 authors author NOUN ffhd-56 27 2 may may AUX ffhd-56 27 3 post post VERB ffhd-56 27 4 and and CCONJ ffhd-56 27 5 share share VERB ffhd-56 27 6 their their PRON ffhd-56 27 7 published publish VERB ffhd-56 27 8 work work NOUN ffhd-56 27 9 freely freely ADV ffhd-56 27 10 , , PUNCT ffhd-56 27 11 provided provide VERB ffhd-56 27 12 that that SCONJ ffhd-56 27 13 the the DET ffhd-56 27 14 original original ADJ ffhd-56 27 15 publication publication NOUN ffhd-56 27 16 in in ADP ffhd-56 27 17 this this DET ffhd-56 27 18 journal journal NOUN ffhd-56 27 19 is be AUX ffhd-56 27 20 acknowledged acknowledge VERB ffhd-56 27 21 . . PUNCT ffhd-56 28 1 by by ADP ffhd-56 28 2 submitting submit VERB ffhd-56 28 3 to to ADP ffhd-56 28 4 this this DET ffhd-56 28 5 journal journal NOUN ffhd-56 28 6 , , PUNCT ffhd-56 28 7 authors author NOUN ffhd-56 28 8 confirm confirm VERB ffhd-56 28 9 that that SCONJ ffhd-56 28 10 their their PRON ffhd-56 28 11 manuscripts manuscript NOUN ffhd-56 28 12 are be AUX ffhd-56 28 13 original original ADJ ffhd-56 28 14 , , PUNCT ffhd-56 28 15 not not PART ffhd-56 28 16 under under ADP ffhd-56 28 17 consideration consideration NOUN ffhd-56 28 18 elsewhere elsewhere ADV ffhd-56 28 19 , , PUNCT ffhd-56 28 20 and and CCONJ ffhd-56 28 21 that that SCONJ ffhd-56 28 22 they they PRON ffhd-56 28 23 hold hold VERB ffhd-56 28 24 the the DET ffhd-56 28 25 necessary necessary ADJ ffhd-56 28 26 rights right NOUN ffhd-56 28 27 to to PART ffhd-56 28 28 grant grant VERB ffhd-56 28 29 this this DET ffhd-56 28 30 license license NOUN ffhd-56 28 31 . . PUNCT ffhd-56 29 1 the the DET ffhd-56 29 2 functional functional ADJ ffhd-56 29 3 food food NOUN ffhd-56 29 4 center center NOUN ffhd-56 29 5 encourages encourage VERB ffhd-56 29 6 open open ADJ ffhd-56 29 7 scientific scientific ADJ ffhd-56 29 8 exchange exchange NOUN ffhd-56 29 9 and and CCONJ ffhd-56 29 10 allows allow VERB ffhd-56 29 11 derivative derivative ADJ ffhd-56 29 12 and and CCONJ ffhd-56 29 13 extended extended ADJ ffhd-56 29 14 works work NOUN ffhd-56 29 15 , , PUNCT ffhd-56 29 16 provided provide VERB ffhd-56 29 17 attribution attribution NOUN ffhd-56 29 18 to to ADP ffhd-56 29 19 the the DET ffhd-56 29 20 original original ADJ ffhd-56 29 21 publication publication NOUN ffhd-56 29 22 is be AUX ffhd-56 29 23 maintained maintain VERB ffhd-56 29 24 . . PUNCT ffhd-56 30 1 about about ADP ffhd-56 30 2 the the DET ffhd-56 30 3 journal journal NOUN ffhd-56 30 4             SPACE ffhd-56 30 5 editing edit VERB ffhd-56 30 6 services service NOUN ffhd-56 30 7             SPACE ffhd-56 30 8 graphical graphical ADJ ffhd-56 30 9 abstract abstract ADJ ffhd-56 30 10             SPACE ffhd-56 30 11 journal journal NOUN ffhd-56 30 12 insights insight NOUN ffhd-56 30 13                 SPACE ffhd-56 30 14 submissions submission NOUN ffhd-56 30 15                 SPACE ffhd-56 30 16 editorial editorial ADJ ffhd-56 30 17 team team NOUN ffhd-56 30 18                 SPACE ffhd-56 30 19 privacy privacy NOUN ffhd-56 30 20 statement statement NOUN ffhd-56 30 21                 SPACE ffhd-56 30 22 contact contact NOUN ffhd-56 30 23                 SPACE ffhd-56 30 24 current current ADJ ffhd-56 30 25                 SPACE ffhd-56 30 26 archives archive NOUN ffhd-56 30 27     SPACE ffhd-56 30 28 open open ADJ ffhd-56 30 29 journal journal NOUN ffhd-56 30 30 systems system NOUN ffhd-56 30 31 hosting host VERB ffhd-56 30 32 and and CCONJ ffhd-56 30 33 support support NOUN ffhd-56 30 34 by by ADP ffhd-56 30 35 : : PUNCT ffhd-56 30 36 openjournalsystems.com openjournalsystems.com X