The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy overweight participants | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 5 No. 6 (2015): June 2015 / Research Articles The effect of extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomeraâ„¢) on body weight and lipid parameters of healthy overweight participants Authors Boris Azantsa Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, SW Region, Cameroon;Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Dieudonne Kuate Program in Nutrition, School of Health Sciences Universiti Sains Malaysia, 16150 Kubang Kerian Kelantan, Malaysia; Raoul Chakokam Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Ghislain Paka Department of Biochemistry, Faculty of Science, BP 812, University of Yaounde 1, Yaounde, Cameroon; Barbara Bartholomew PhytoQuest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK Robert Nash PhytoQuest Limited, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK DOI: https://doi.org/10.31989/ffhd.v5i6.184 Abstract Background: Previous work reported the benefits of extracts of 2 Cameroonian spices – Irvingia gabonensis and Dichrostachys glomerata— on obese people with metabolic syndrome. Considering the physio-metabolic changes that accompany obesity, the present study investigates the effects of these extracts on healthy overweight participants over an 8-week test period. Methods: The study was an 8 week randomized double-blind, placebo controlled design involving 48 overweight (BMI 26 – 30) participants (27 females and 19 males), divided into 3 groups – placebo, 300 mg I. gabonensis extract (IGOB131), or 300 mg D. glomerata extract (DyglomeraTM). Capsules containing the placebo or the test formulations were administered once daily before the main meal of the day. No major dietary changes or changes in physical activity were demonstrated during the study. Weight and blood lipid parameters were measured at baseline, and at the 4 and 8 weeks interval. Results: Compared to the placebo group, there were significant (p<0.05) reductions in weight of participants in both test groups over the 8 week period. However, these significant changes were not observed in the initial 4 weeks, even though the lipid parameters in the test groups changed significantly (p<0.05). Conclusion: The extracts of Irvingia gabonensis and Dichrostachys glomerata, at a dose of 300 mg per day, were effective in reducing weight and positively modifying lipid parameters in healthy overweight participants. Keywords: Overweight, Dichrostachys, Irvingia, waist-hip circumference, blood lipids. Downloads [Abstract] [Full Article] Published 2015-06-09 Issue Vol. 5 No. 6 (2015): June 2015 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged. By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained. About the Journal      Editing Services      Graphical Abstract      Journal Insights        Submissions        Editorial Team       Privacy Statement        Contact        Current        Archives   Open Journal Systems Hosting and Support by: OpenJournalSystems.com