Preclinical study of goat milk kefir as an antihyperglycemic food | Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Skip to main content Skip to main navigation menu Skip to site footer Open Menu Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 Home Food Science Publisher Functional Food Center Current Archives About About the Journal Aims and Scope Contact Editing Services Editorial Team Express Peer Review Graphical Abstract Journal Insights Privacy Statement Submissions Announcements Search Search Register Login Home / Archives / Vol. 12 No. 12 (2022): December 2022 / Research Articles Preclinical study of goat milk kefir as an antihyperglycemic food Authors Siti Susanti Food Technology, Department of Agriculture, Faculty of Animal Sciences and Agriculture, Diponegoro University, Semarang, Indonesia Nurwantoro Nurwantoro Food Technology, Department of Agriculture, Faculty of Animal Sciences and Agriculture, Diponegoro University, Semarang, Indonesia Jessen Juan Elto Food Technology, Department of Agriculture, Faculty of Animal Sciences and Agriculture, Diponegoro University, Semarang, Indonesia Trilaksana Nugroho Faculty of Medicine, Diponegoro University, Semarang, Indonesia Ade Erma Suryani Research Center for Food Technology and Processing-National Research and Innovation Agenc Heni Rizqiati Food Technology, Department of Agriculture, Faculty of Animal Sciences and Agriculture, Diponegoro University, Semarang, Indonesia DOI: https://doi.org/10.31989/ffhd.v12i12.987 Abstract Background: Goat milk kefir is a functional food with numerous health benefits, including blood sugar control, cholesterol reduction, and improved digestive health. This study aims to determine the effect of kefir consumption on blood glucose levels in hyperglycaemic mice (Mus musculus) without affecting another blood chemistry.  This study compared goat milk kefir products to other processed milk products considered to be capable of controlling and reducing blood sugar levels.  Objective:This study aimed to compare goat milk kefir products to other processed food products considered to be capable of controlling and reducing blood sugar levels. Methods: Twenty-one mice, as experimental animals, were induced for 21 days with the high-fat and high fructose diet to increase blood sugar levels. After induction, mice were divided into 3 groups according to treatment, namely oral administration of additional distilled water (placebo), diabetasol® (positive control), and goat's milk kefir with each group consisting of 9 individuals.  Results: Treatment showed significant effect on the blood glucose and β-ketone level. Diabetasol®  and Goat kefir supplemented mice had a lower blood glucose level than control (p < 0.05) and goat kefir supplemented mice had lower blood β-ketone level than control and Diabetasol® (p< 0.05). Meanwhile, hematocrit and hemoglobin levels did not show significant differences between treatments. Conclusion: The results suggested that goat milk kefir has preclinical potential as an antihyperglycemic functional food without affecting other blood chemistry profiles. Keywords: Antihyperglycemic, blood sugar, goat kefir Downloads Abstract [Full Article] Published 2022-12-08 Issue Vol. 12 No. 12 (2022): December 2022 Section Research Articles License Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged. By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained. About the Journal      Editing Services      Graphical Abstract      Journal Insights        Submissions        Editorial Team       Privacy Statement        Contact        Current        Archives   Open Journal Systems Hosting and Support by: OpenJournalSystems.com