id	sid	tid	token	lemma	pos
gsrj-10	1	1	interplay	interplay	NOUN
gsrj-10	1	2	of	of	ADP
gsrj-10	1	3	nicotine	nicotine	NOUN
gsrj-10	1	4	and	and	CCONJ
gsrj-10	1	5	social	social	ADJ
gsrj-10	1	6	stress	stress	NOUN
gsrj-10	1	7	mediate	mediate	VERB
gsrj-10	1	8	dopaminergic	dopaminergic	ADJ
gsrj-10	1	9	neuron	neuron	NOUN
gsrj-10	1	10	firing	fire	VERB
gsrj-10	1	11	in	in	ADP
gsrj-10	1	12	the	the	DET
gsrj-10	1	13	ventral	ventral	ADJ
gsrj-10	1	14	tegmental	tegmental	ADJ
gsrj-10	1	15	area	area	NOUN
gsrj-10	1	16	—	—	PUNCT
gsrj-10	1	17	nucleus	nucleus	NOUN
gsrj-10	1	18	accumbens	accumben	NOUN
gsrj-10	1	19	pathway	pathway	NOUN
gsrj-10	1	20	,	,	PUNCT
gsrj-10	1	21	contributing	contribute	VERB
gsrj-10	1	22	to	to	ADP
gsrj-10	1	23	stress	stress	NOUN
gsrj-10	1	24	and	and	CCONJ
gsrj-10	1	25	depressive	depressive	ADJ
gsrj-10	1	26	mood	mood	NOUN
gsrj-10	1	27	disorders	disorder	NOUN
gsrj-10	1	28	danya	danya	PROPN
gsrj-10	1	29	adams	adams	PROPN
gsrj-10	1	30	,	,	PUNCT
gsrj-10	1	31	nicholas	nicholas	PROPN
gsrj-10	1	32	kaliss	kaliss	PROPN
gsrj-10	1	33	,	,	PUNCT
gsrj-10	1	34	alexander	alexander	PROPN
gsrj-10	1	35	missner	missner	PROPN
gsrj-10	1	36	,	,	PUNCT
gsrj-10	1	37	mary	mary	PROPN
gsrj-10	1	38	meg	meg	PROPN
gsrj-10	1	39	valentine	valentine	PROPN
gsrj-10	1	40	volume	volume	NOUN
gsrj-10	1	41	one	one	NUM
gsrj-10	1	42	edition	edition	NOUN
gsrj-10	1	43	one	one	NUM
gsrj-10	1	44	february	february	PROPN
gsrj-10	1	45	2021	2021	NUM
gsrj-10	1	46	georgetown	georgetown	PROPN
gsrj-10	1	47	scientific	scientific	PROPN
gsrj-10	1	48	research	research	PROPN
gsrj-10	1	49	journal	journal	PROPN
gsrj-10	1	50	70	70	NUM
gsrj-10	1	51	georgetown	georgetown	PROPN
gsrj-10	1	52	scientific	scientific	PROPN
gsrj-10	1	53	research	research	NOUN
gsrj-10	1	54	journal	journal	NOUN
gsrj-10	1	55	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	VERB
gsrj-10	1	56	the	the	DET
gsrj-10	1	57	interplay	interplay	NOUN
gsrj-10	1	58	of	of	ADP
gsrj-10	1	59	nicotine	nicotine	NOUN
gsrj-10	1	60	and	and	CCONJ
gsrj-10	1	61	social	social	ADJ
gsrj-10	1	62	stress	stress	NOUN
gsrj-10	1	63	mediate	mediate	VERB
gsrj-10	1	64	dopaminergic	dopaminergic	ADJ
gsrj-10	1	65	neuron	neuron	NOUN
gsrj-10	1	66	firing	fire	VERB
gsrj-10	1	67	in	in	ADP
gsrj-10	1	68	the	the	DET
gsrj-10	1	69	ventral	ventral	ADJ
gsrj-10	1	70	tegmental	tegmental	ADJ
gsrj-10	1	71	area	area	NOUN
gsrj-10	1	72	nucleus	nucleus	PROPN
gsrj-10	1	73	accumbens	accumben	VERB
gsrj-10	1	74	pathway	pathway	NOUN
gsrj-10	1	75	,	,	PUNCT
gsrj-10	1	76	contributing	contribute	VERB
gsrj-10	1	77	to	to	ADP
gsrj-10	1	78	stress	stress	NOUN
gsrj-10	1	79	and	and	CCONJ
gsrj-10	1	80	depressive	depressive	ADJ
gsrj-10	1	81	mood	mood	NOUN
gsrj-10	1	82	disorders	disorder	NOUN
gsrj-10	1	83	.	.	PUNCT
gsrj-10	2	1	danya	danya	PROPN
gsrj-10	2	2	adams	adams	PROPN
gsrj-10	2	3	*	*	PROPN
gsrj-10	2	4	,	,	PUNCT
gsrj-10	2	5	nicholas	nicholas	PROPN
gsrj-10	2	6	kaliss	kaliss	PROPN
gsrj-10	2	7	*	*	PROPN
gsrj-10	2	8	,	,	PUNCT
gsrj-10	2	9	alexander	alexander	PROPN
gsrj-10	2	10	missner	missner	PROPN
gsrj-10	2	11	*	*	PROPN
gsrj-10	2	12	,	,	PUNCT
gsrj-10	2	13	mary	mary	PROPN
gsrj-10	2	14	meg	meg	PROPN
gsrj-10	2	15	valentine	valentine	PROPN
gsrj-10	2	16	*	*	PROPN
gsrj-10	2	17	1	1	NUM
gsrj-10	2	18	department	department	NOUN
gsrj-10	2	19	of	of	ADP
gsrj-10	2	20	biology	biology	NOUN
gsrj-10	2	21	,	,	PUNCT
gsrj-10	2	22	georgetown	georgetown	PROPN
gsrj-10	2	23	university	university	PROPN
gsrj-10	2	24	,	,	PUNCT
gsrj-10	2	25	washington	washington	PROPN
gsrj-10	2	26	,	,	PUNCT
gsrj-10	2	27	dc	dc	PROPN
gsrj-10	2	28	,	,	PUNCT
gsrj-10	2	29	usa	usa	PROPN
gsrj-10	2	30	*	*	PUNCT
gsrj-10	2	31	indicates	indicate	VERB
gsrj-10	2	32	equal	equal	ADJ
gsrj-10	2	33	contribution	contribution	NOUN
gsrj-10	2	34	e	e	NOUN
gsrj-10	2	35	-	-	NOUN
gsrj-10	2	36	mail	mail	NOUN
gsrj-10	2	37	:	:	PUNCT
gsrj-10	3	1	daa112@georgetown.edu	daa112@georgetown.edu	PROPN
gsrj-10	3	2	,	,	PUNCT
gsrj-10	3	3	ndk14@georgetown.edu	ndk14@georgetown.edu	PROPN
gsrj-10	3	4	,	,	PUNCT
gsrj-10	3	5	am3212@georgetown.edu	am3212@georgetown.edu	PROPN
gsrj-10	3	6	,	,	PUNCT
gsrj-10	3	7	mmv57@georgetown.edu	mmv57@georgetown.edu	NUM
gsrj-10	3	8	abstract	abstract	ADJ
gsrj-10	3	9	nicotine	nicotine	NOUN
gsrj-10	3	10	use	use	NOUN
gsrj-10	3	11	and	and	CCONJ
gsrj-10	3	12	social	social	ADJ
gsrj-10	3	13	stress	stress	NOUN
gsrj-10	3	14	have	have	VERB
gsrj-10	3	15	a	a	DET
gsrj-10	3	16	complex	complex	ADJ
gsrj-10	3	17	interplay	interplay	NOUN
gsrj-10	3	18	,	,	PUNCT
gsrj-10	3	19	which	which	PRON
gsrj-10	3	20	has	have	AUX
gsrj-10	3	21	been	be	AUX
gsrj-10	3	22	shown	show	VERB
gsrj-10	3	23	to	to	PART
gsrj-10	3	24	be	be	AUX
gsrj-10	3	25	mediated	mediate	VERB
gsrj-10	3	26	by	by	ADP
gsrj-10	3	27	cholinergic	cholinergic	ADJ
gsrj-10	3	28	neurons	neuron	NOUN
gsrj-10	3	29	in	in	ADP
gsrj-10	3	30	the	the	DET
gsrj-10	3	31	ventral	ventral	ADJ
gsrj-10	3	32	tegmental	tegmental	ADJ
gsrj-10	3	33	area	area	NOUN
gsrj-10	3	34	(	(	PUNCT
gsrj-10	3	35	vta	vta	PROPN
gsrj-10	3	36	)	)	PUNCT
gsrj-10	3	37	.	.	PUNCT
gsrj-10	4	1	social	social	ADJ
gsrj-10	4	2	stress	stress	NOUN
gsrj-10	4	3	is	be	AUX
gsrj-10	4	4	often	often	ADV
gsrj-10	4	5	comorbid	comorbid	ADJ
gsrj-10	4	6	with	with	ADP
gsrj-10	4	7	nicotine	nicotine	NOUN
gsrj-10	4	8	consumption	consumption	NOUN
gsrj-10	4	9	,	,	PUNCT
gsrj-10	4	10	and	and	CCONJ
gsrj-10	4	11	the	the	DET
gsrj-10	4	12	presence	presence	NOUN
gsrj-10	4	13	of	of	ADP
gsrj-10	4	14	either	either	CCONJ
gsrj-10	4	15	stress	stress	NOUN
gsrj-10	4	16	or	or	CCONJ
gsrj-10	4	17	nicotine	nicotine	NOUN
gsrj-10	4	18	use	use	NOUN
gsrj-10	4	19	significantly	significantly	ADV
gsrj-10	4	20	increases	increase	VERB
gsrj-10	4	21	the	the	DET
gsrj-10	4	22	risk	risk	NOUN
gsrj-10	4	23	of	of	ADP
gsrj-10	4	24	developing	develop	VERB
gsrj-10	4	25	the	the	DET
gsrj-10	4	26	other	other	ADJ
gsrj-10	4	27	.	.	PUNCT
gsrj-10	5	1	in	in	ADP
gsrj-10	5	2	fact	fact	NOUN
gsrj-10	5	3	,	,	PUNCT
gsrj-10	5	4	it	it	PRON
gsrj-10	5	5	has	have	AUX
gsrj-10	5	6	been	be	AUX
gsrj-10	5	7	shown	show	VERB
gsrj-10	5	8	in	in	ADP
gsrj-10	5	9	mice	mouse	NOUN
gsrj-10	5	10	that	that	PRON
gsrj-10	5	11	nicotine	nicotine	VERB
gsrj-10	5	12	injection	injection	NOUN
gsrj-10	5	13	is	be	AUX
gsrj-10	5	14	sufficient	sufficient	ADJ
gsrj-10	5	15	to	to	PART
gsrj-10	5	16	increase	increase	VERB
gsrj-10	5	17	susceptibility	susceptibility	NOUN
gsrj-10	5	18	to	to	ADP
gsrj-10	5	19	social	social	ADJ
gsrj-10	5	20	defeat	defeat	NOUN
gsrj-10	5	21	,	,	PUNCT
gsrj-10	5	22	a	a	DET
gsrj-10	5	23	reliable	reliable	ADJ
gsrj-10	5	24	model	model	NOUN
gsrj-10	5	25	for	for	ADP
gsrj-10	5	26	stress	stress	NOUN
gsrj-10	5	27	and	and	CCONJ
gsrj-10	5	28	anxiety	anxiety	NOUN
gsrj-10	5	29	-	-	PUNCT
gsrj-10	5	30	like	like	ADJ
gsrj-10	5	31	behavior	behavior	NOUN
gsrj-10	5	32	.	.	PUNCT
gsrj-10	6	1	stressful	stressful	ADJ
gsrj-10	6	2	events	event	NOUN
gsrj-10	6	3	can	can	AUX
gsrj-10	6	4	molecularly	molecularly	ADV
gsrj-10	6	5	remodel	remodel	VERB
gsrj-10	6	6	cholinergic	cholinergic	ADJ
gsrj-10	6	7	synapses	synapsis	NOUN
gsrj-10	6	8	,	,	PUNCT
gsrj-10	6	9	inducing	induce	VERB
gsrj-10	6	10	the	the	DET
gsrj-10	6	11	production	production	NOUN
gsrj-10	6	12	of	of	ADP
gsrj-10	6	13	more	more	ADJ
gsrj-10	6	14	cholinergic	cholinergic	ADJ
gsrj-10	6	15	transporters	transporter	NOUN
gsrj-10	6	16	and	and	CCONJ
gsrj-10	6	17	increasing	increase	VERB
gsrj-10	6	18	the	the	DET
gsrj-10	6	19	number	number	NOUN
gsrj-10	6	20	of	of	ADP
gsrj-10	6	21	nicotinic	nicotinic	ADJ
gsrj-10	6	22	receptor	receptor	NOUN
gsrj-10	6	23	binding	bind	VERB
gsrj-10	6	24	sites	site	NOUN
gsrj-10	6	25	.	.	PUNCT
gsrj-10	7	1	one	one	NUM
gsrj-10	7	2	way	way	NOUN
gsrj-10	7	3	stress	stress	NOUN
gsrj-10	7	4	and	and	CCONJ
gsrj-10	7	5	nicotine	nicotine	VERB
gsrj-10	7	6	remodel	remodel	NOUN
gsrj-10	7	7	cholinergic	cholinergic	ADJ
gsrj-10	7	8	synapses	synapsis	NOUN
gsrj-10	7	9	are	be	AUX
gsrj-10	7	10	through	through	ADP
gsrj-10	7	11	long	long	ADJ
gsrj-10	7	12	-	-	PUNCT
gsrj-10	7	13	term	term	NOUN
gsrj-10	7	14	potentiation	potentiation	NOUN
gsrj-10	7	15	(	(	PUNCT
gsrj-10	7	16	ltp	ltp	NOUN
gsrj-10	7	17	)	)	PUNCT
gsrj-10	7	18	in	in	ADP
gsrj-10	7	19	cholinergic	cholinergic	ADJ
gsrj-10	7	20	pathways	pathway	NOUN
gsrj-10	7	21	in	in	ADP
gsrj-10	7	22	the	the	DET
gsrj-10	7	23	vta	vta	NOUN
gsrj-10	7	24	,	,	PUNCT
gsrj-10	7	25	enhancing	enhance	VERB
gsrj-10	7	26	the	the	DET
gsrj-10	7	27	experience	experience	NOUN
gsrj-10	7	28	of	of	ADP
gsrj-10	7	29	stress	stress	NOUN
gsrj-10	7	30	and	and	CCONJ
gsrj-10	7	31	the	the	DET
gsrj-10	7	32	effects	effect	NOUN
gsrj-10	7	33	of	of	ADP
gsrj-10	7	34	addiction	addiction	NOUN
gsrj-10	7	35	.	.	PUNCT
gsrj-10	8	1	despite	despite	SCONJ
gsrj-10	8	2	both	both	DET
gsrj-10	8	3	primarily	primarily	ADV
gsrj-10	8	4	acting	act	VERB
gsrj-10	8	5	on	on	ADP
gsrj-10	8	6	the	the	DET
gsrj-10	8	7	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	8	8	subtype	subtype	NOUN
gsrj-10	8	9	nicotine	nicotine	NOUN
gsrj-10	8	10	receptor	receptor	NOUN
gsrj-10	8	11	,	,	PUNCT
gsrj-10	8	12	nicotine	nicotine	NOUN
gsrj-10	8	13	and	and	CCONJ
gsrj-10	8	14	stress	stress	NOUN
gsrj-10	8	15	induce	induce	VERB
gsrj-10	8	16	ltp	ltp	NOUN
gsrj-10	8	17	in	in	ADP
gsrj-10	8	18	vastly	vastly	ADV
gsrj-10	8	19	different	different	ADJ
gsrj-10	8	20	ways	way	NOUN
gsrj-10	8	21	:	:	PUNCT
gsrj-10	8	22	nicotine	nicotine	NOUN
gsrj-10	8	23	acts	act	VERB
gsrj-10	8	24	quickly	quickly	ADV
gsrj-10	8	25	via	via	ADP
gsrj-10	8	26	ligand	ligand	NOUN
gsrj-10	8	27	-	-	PUNCT
gsrj-10	8	28	gated	gate	VERB
gsrj-10	8	29	ion	ion	NOUN
gsrj-10	8	30	channels	channel	NOUN
gsrj-10	8	31	while	while	SCONJ
gsrj-10	8	32	stress	stress	NOUN
gsrj-10	8	33	activates	activate	VERB
gsrj-10	8	34	a	a	DET
gsrj-10	8	35	slower	slow	ADJ
gsrj-10	8	36	hormonal	hormonal	NOUN
gsrj-10	8	37	-	-	PUNCT
gsrj-10	8	38	induced	induce	VERB
gsrj-10	8	39	g	g	NOUN
gsrj-10	8	40	-	-	PUNCT
gsrj-10	8	41	protein	protein	NOUN
gsrj-10	8	42	coupled	couple	VERB
gsrj-10	8	43	receptor	receptor	NOUN
gsrj-10	8	44	pathway	pathway	NOUN
gsrj-10	8	45	.	.	PUNCT
gsrj-10	9	1	these	these	DET
gsrj-10	9	2	findings	finding	NOUN
gsrj-10	9	3	suggest	suggest	VERB
gsrj-10	9	4	that	that	SCONJ
gsrj-10	9	5	dopaminergic	dopaminergic	ADJ
gsrj-10	9	6	vta	vta	NOUN
gsrj-10	9	7	neurons	neuron	NOUN
gsrj-10	9	8	may	may	AUX
gsrj-10	9	9	be	be	AUX
gsrj-10	9	10	a	a	DET
gsrj-10	9	11	useful	useful	ADJ
gsrj-10	9	12	therapeutic	therapeutic	ADJ
gsrj-10	9	13	target	target	NOUN
gsrj-10	9	14	for	for	ADP
gsrj-10	9	15	depression	depression	NOUN
gsrj-10	9	16	,	,	PUNCT
gsrj-10	9	17	anxiety	anxiety	NOUN
gsrj-10	9	18	,	,	PUNCT
gsrj-10	9	19	and	and	CCONJ
gsrj-10	9	20	other	other	ADJ
gsrj-10	9	21	stress	stress	NOUN
gsrj-10	9	22	-	-	PUNCT
gsrj-10	9	23	related	relate	VERB
gsrj-10	9	24	disorders	disorder	NOUN
gsrj-10	9	25	.	.	PUNCT
gsrj-10	10	1	deep	deep	ADJ
gsrj-10	10	2	brain	brain	NOUN
gsrj-10	10	3	stimulation	stimulation	NOUN
gsrj-10	10	4	has	have	AUX
gsrj-10	10	5	preliminarily	preliminarily	ADV
gsrj-10	10	6	shown	show	VERB
gsrj-10	10	7	to	to	PART
gsrj-10	10	8	be	be	AUX
gsrj-10	10	9	a	a	DET
gsrj-10	10	10	potential	potential	ADJ
gsrj-10	10	11	therapeutic	therapeutic	ADJ
gsrj-10	10	12	treatment	treatment	NOUN
gsrj-10	10	13	for	for	ADP
gsrj-10	10	14	untreatable	untreatable	ADJ
gsrj-10	10	15	depression	depression	NOUN
gsrj-10	10	16	,	,	PUNCT
gsrj-10	10	17	especially	especially	ADV
gsrj-10	10	18	when	when	SCONJ
gsrj-10	10	19	it	it	PRON
gsrj-10	10	20	targets	target	VERB
gsrj-10	10	21	the	the	DET
gsrj-10	10	22	medial	medial	ADJ
gsrj-10	10	23	forebrain	forebrain	NOUN
gsrj-10	10	24	bundle	bundle	NOUN
gsrj-10	10	25	within	within	ADP
gsrj-10	10	26	the	the	DET
gsrj-10	10	27	vta	vta	PROPN
gsrj-10	10	28	-	-	PUNCT
gsrj-10	10	29	nac	nac	PROPN
gsrj-10	10	30	pathway	pathway	NOUN
gsrj-10	10	31	.	.	PUNCT
gsrj-10	11	1	sleep	sleep	NOUN
gsrj-10	11	2	patterns	pattern	NOUN
gsrj-10	11	3	are	be	AUX
gsrj-10	11	4	also	also	ADV
gsrj-10	11	5	partially	partially	ADV
gsrj-10	11	6	regulated	regulate	VERB
gsrj-10	11	7	by	by	ADP
gsrj-10	11	8	dopaminergic	dopaminergic	ADJ
gsrj-10	11	9	vta	vta	NOUN
gsrj-10	11	10	neurons	neuron	NOUN
gsrj-10	11	11	,	,	PUNCT
gsrj-10	11	12	and	and	CCONJ
gsrj-10	11	13	sleep	sleep	VERB
gsrj-10	11	14	deficits	deficit	NOUN
gsrj-10	11	15	may	may	AUX
gsrj-10	11	16	contribute	contribute	VERB
gsrj-10	11	17	to	to	ADP
gsrj-10	11	18	social	social	ADJ
gsrj-10	11	19	stress	stress	NOUN
gsrj-10	11	20	and	and	CCONJ
gsrj-10	11	21	other	other	ADJ
gsrj-10	11	22	depressive	depressive	ADJ
gsrj-10	11	23	symptoms	symptom	NOUN
gsrj-10	11	24	.	.	PUNCT
gsrj-10	12	1	the	the	DET
gsrj-10	12	2	role	role	NOUN
gsrj-10	12	3	of	of	ADP
gsrj-10	12	4	nicotine	nicotine	ADJ
gsrj-10	12	5	dependence	dependence	NOUN
gsrj-10	12	6	in	in	ADP
gsrj-10	12	7	stress	stress	NOUN
gsrj-10	12	8	-	-	PUNCT
gsrj-10	12	9	related	relate	VERB
gsrj-10	12	10	mental	mental	ADJ
gsrj-10	12	11	illnesses	illness	NOUN
gsrj-10	12	12	is	be	AUX
gsrj-10	12	13	especially	especially	ADV
gsrj-10	12	14	important	important	ADJ
gsrj-10	12	15	to	to	PART
gsrj-10	12	16	consider	consider	VERB
gsrj-10	12	17	given	give	VERB
gsrj-10	12	18	the	the	DET
gsrj-10	12	19	recent	recent	ADJ
gsrj-10	12	20	increase	increase	NOUN
gsrj-10	12	21	in	in	ADP
gsrj-10	12	22	adolescent	adolescent	ADJ
gsrj-10	12	23	nicotine	nicotine	NOUN
gsrj-10	12	24	use	use	NOUN
gsrj-10	12	25	with	with	ADP
gsrj-10	12	26	the	the	DET
gsrj-10	12	27	advent	advent	NOUN
gsrj-10	12	28	of	of	ADP
gsrj-10	12	29	vaping	vaping	NOUN
gsrj-10	12	30	.	.	PUNCT
gsrj-10	13	1	adolescents	adolescent	NOUN
gsrj-10	13	2	already	already	ADV
gsrj-10	13	3	have	have	VERB
gsrj-10	13	4	an	an	DET
gsrj-10	13	5	increased	increase	VERB
gsrj-10	13	6	risk	risk	NOUN
gsrj-10	13	7	for	for	ADP
gsrj-10	13	8	developing	develop	VERB
gsrj-10	13	9	mental	mental	ADJ
gsrj-10	13	10	illnesses	illness	NOUN
gsrj-10	13	11	,	,	PUNCT
gsrj-10	13	12	and	and	CCONJ
gsrj-10	13	13	it	it	PRON
gsrj-10	13	14	is	be	AUX
gsrj-10	13	15	important	important	ADJ
gsrj-10	13	16	that	that	SCONJ
gsrj-10	13	17	young	young	ADJ
gsrj-10	13	18	people	people	NOUN
gsrj-10	13	19	are	be	AUX
gsrj-10	13	20	made	make	VERB
gsrj-10	13	21	aware	aware	ADJ
gsrj-10	13	22	of	of	ADP
gsrj-10	13	23	the	the	DET
gsrj-10	13	24	potential	potential	ADJ
gsrj-10	13	25	psychological	psychological	ADJ
gsrj-10	13	26	harms	harm	NOUN
gsrj-10	13	27	of	of	ADP
gsrj-10	13	28	nicotine	nicotine	NOUN
gsrj-10	13	29	use	use	NOUN
gsrj-10	13	30	.	.	PUNCT
gsrj-10	14	1	keywords	keyword	NOUN
gsrj-10	14	2	:	:	PUNCT
gsrj-10	14	3	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	14	4	subtype	subtype	NOUN
gsrj-10	14	5	nicotine	nicotine	NOUN
gsrj-10	14	6	receptor	receptor	NOUN
gsrj-10	14	7	,	,	PUNCT
gsrj-10	14	8	cholinergic	cholinergic	ADJ
gsrj-10	14	9	synapses	synapsis	NOUN
gsrj-10	14	10	,	,	PUNCT
gsrj-10	14	11	long	long	ADJ
gsrj-10	14	12	-	-	PUNCT
gsrj-10	14	13	term	term	NOUN
gsrj-10	14	14	potentiation	potentiation	NOUN
gsrj-10	14	15	,	,	PUNCT
gsrj-10	14	16	nicotine	nicotine	NOUN
gsrj-10	14	17	,	,	PUNCT
gsrj-10	14	18	stress	stress	NOUN
gsrj-10	14	19	,	,	PUNCT
gsrj-10	14	20	nucleus	nucleus	ADJ
gsrj-10	14	21	accumbens	accumben	NOUN
gsrj-10	14	22	,	,	PUNCT
gsrj-10	14	23	and	and	CCONJ
gsrj-10	14	24	ventral	ventral	ADJ
gsrj-10	14	25	tegmental	tegmental	ADJ
gsrj-10	14	26	area	area	NOUN
gsrj-10	14	27	71	71	NUM
gsrj-10	14	28	georgetown	georgetown	PROPN
gsrj-10	14	29	scientific	scientific	PROPN
gsrj-10	14	30	research	research	NOUN
gsrj-10	14	31	journal	journal	NOUN
gsrj-10	14	32	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	14	33	1	1	NUM
gsrj-10	14	34	.	.	PUNCT
gsrj-10	15	1	introduction	introduction	NOUN
gsrj-10	15	2	according	accord	VERB
gsrj-10	15	3	to	to	ADP
gsrj-10	15	4	the	the	DET
gsrj-10	15	5	national	national	PROPN
gsrj-10	15	6	institute	institute	PROPN
gsrj-10	15	7	on	on	ADP
gsrj-10	15	8	drug	drug	NOUN
gsrj-10	15	9	abuse	abuse	NOUN
gsrj-10	15	10	,	,	PUNCT
gsrj-10	15	11	nicotine	nicotine	NOUN
gsrj-10	15	12	is	be	AUX
gsrj-10	15	13	classified	classify	VERB
gsrj-10	15	14	as	as	ADP
gsrj-10	15	15	a	a	DET
gsrj-10	15	16	highly	highly	ADV
gsrj-10	15	17	addictive	addictive	ADJ
gsrj-10	15	18	substance	substance	NOUN
gsrj-10	15	19	,	,	PUNCT
gsrj-10	15	20	ranking	rank	VERB
gsrj-10	15	21	among	among	ADP
gsrj-10	15	22	other	other	ADJ
gsrj-10	15	23	drugs	drug	NOUN
gsrj-10	15	24	of	of	ADP
gsrj-10	15	25	abuse	abuse	NOUN
gsrj-10	15	26	such	such	ADJ
gsrj-10	15	27	as	as	ADP
gsrj-10	15	28	cocaine	cocaine	NOUN
gsrj-10	15	29	,	,	PUNCT
gsrj-10	15	30	amphetamines	amphetamine	NOUN
gsrj-10	15	31	,	,	PUNCT
gsrj-10	15	32	and	and	CCONJ
gsrj-10	15	33	heroin.1	heroin.1	NOUN
gsrj-10	15	34	the	the	DET
gsrj-10	15	35	us	us	PROPN
gsrj-10	15	36	department	department	PROPN
gsrj-10	15	37	of	of	ADP
gsrj-10	15	38	health	health	PROPN
gsrj-10	15	39	and	and	CCONJ
gsrj-10	15	40	human	human	ADJ
gsrj-10	15	41	services	service	NOUN
gsrj-10	15	42	estimates	estimate	VERB
gsrj-10	15	43	some	some	DET
gsrj-10	15	44	20	20	NUM
gsrj-10	15	45	%	%	NOUN
gsrj-10	15	46	of	of	ADP
gsrj-10	15	47	all	all	DET
gsrj-10	15	48	americans	american	NOUN
gsrj-10	15	49	are	be	AUX
gsrj-10	15	50	addicted	addict	VERB
gsrj-10	15	51	to	to	ADP
gsrj-10	15	52	nicotine	nicotine	VERB
gsrj-10	15	53	,	,	PUNCT
gsrj-10	15	54	whether	whether	SCONJ
gsrj-10	15	55	by	by	ADP
gsrj-10	15	56	smoking	smoke	VERB
gsrj-10	15	57	cigarettes	cigarette	NOUN
gsrj-10	15	58	,	,	PUNCT
gsrj-10	15	59	chewing	chew	VERB
gsrj-10	15	60	tobacco	tobacco	NOUN
gsrj-10	15	61	,	,	PUNCT
gsrj-10	15	62	or	or	CCONJ
gsrj-10	15	63	vaping.2	vaping.2	PROPN
gsrj-10	15	64	while	while	SCONJ
gsrj-10	15	65	many	many	ADJ
gsrj-10	15	66	—	—	PUNCT
gsrj-10	15	67	up	up	ADP
gsrj-10	15	68	to	to	PART
gsrj-10	15	69	seventy	seventy	NUM
gsrj-10	15	70	percent	percent	NOUN
gsrj-10	15	71	each	each	DET
gsrj-10	15	72	year	year	NOUN
gsrj-10	15	73	—	—	PUNCT
gsrj-10	15	74	will	will	AUX
gsrj-10	15	75	try	try	VERB
gsrj-10	15	76	to	to	PART
gsrj-10	15	77	quit	quit	VERB
gsrj-10	15	78	,	,	PUNCT
gsrj-10	15	79	only	only	ADV
gsrj-10	15	80	around	around	ADV
gsrj-10	15	81	three	three	NUM
gsrj-10	15	82	percent	percent	NOUN
gsrj-10	15	83	will	will	AUX
gsrj-10	15	84	succeed.3	succeed.3	VERB
gsrj-10	15	85	the	the	DET
gsrj-10	15	86	smoking	smoking	NOUN
gsrj-10	15	87	rate	rate	NOUN
gsrj-10	15	88	is	be	AUX
gsrj-10	15	89	doubled	double	VERB
gsrj-10	15	90	in	in	ADP
gsrj-10	15	91	individuals	individual	NOUN
gsrj-10	15	92	who	who	PRON
gsrj-10	15	93	have	have	VERB
gsrj-10	15	94	mood	mood	NOUN
gsrj-10	15	95	or	or	CCONJ
gsrj-10	15	96	stress	stress	NOUN
gsrj-10	15	97	disorders	disorder	NOUN
gsrj-10	15	98	,	,	PUNCT
gsrj-10	15	99	like	like	ADP
gsrj-10	15	100	clinical	clinical	ADJ
gsrj-10	15	101	depression	depression	NOUN
gsrj-10	15	102	,	,	PUNCT
gsrj-10	15	103	and	and	CCONJ
gsrj-10	15	104	although	although	SCONJ
gsrj-10	15	105	these	these	DET
gsrj-10	15	106	individuals	individual	NOUN
gsrj-10	15	107	will	will	AUX
gsrj-10	15	108	attempt	attempt	VERB
gsrj-10	15	109	to	to	PART
gsrj-10	15	110	quit	quit	VERB
gsrj-10	15	111	at	at	ADP
gsrj-10	15	112	the	the	DET
gsrj-10	15	113	same	same	ADJ
gsrj-10	15	114	rates	rate	NOUN
gsrj-10	15	115	,	,	PUNCT
gsrj-10	15	116	their	their	PRON
gsrj-10	15	117	chances	chance	NOUN
gsrj-10	15	118	of	of	ADP
gsrj-10	15	119	success	success	NOUN
gsrj-10	15	120	are	be	AUX
gsrj-10	15	121	even	even	ADV
gsrj-10	15	122	lower	low	ADJ
gsrj-10	15	123	than	than	ADP
gsrj-10	15	124	their	their	PRON
gsrj-10	15	125	neurotypical	neurotypical	ADJ
gsrj-10	15	126	counterparts.4	counterparts.4	NOUN
gsrj-10	15	127	each	each	DET
gsrj-10	15	128	condition	condition	NOUN
gsrj-10	15	129	heightens	heighten	VERB
gsrj-10	15	130	the	the	DET
gsrj-10	15	131	risk	risk	NOUN
gsrj-10	15	132	of	of	ADP
gsrj-10	15	133	developing	develop	VERB
gsrj-10	15	134	the	the	DET
gsrj-10	15	135	other	other	ADJ
gsrj-10	15	136	:	:	PUNCT
gsrj-10	15	137	depressed	depressed	ADJ
gsrj-10	15	138	individuals	individual	NOUN
gsrj-10	15	139	are	be	AUX
gsrj-10	15	140	more	more	ADV
gsrj-10	15	141	likely	likely	ADJ
gsrj-10	15	142	to	to	PART
gsrj-10	15	143	begin	begin	VERB
gsrj-10	15	144	smoking	smoking	NOUN
gsrj-10	15	145	and	and	CCONJ
gsrj-10	15	146	experience	experience	VERB
gsrj-10	15	147	more	more	ADV
gsrj-10	15	148	potent	potent	ADJ
gsrj-10	15	149	withdrawal	withdrawal	NOUN
gsrj-10	15	150	symptoms	symptom	NOUN
gsrj-10	15	151	when	when	SCONJ
gsrj-10	15	152	they	they	PRON
gsrj-10	15	153	try	try	VERB
gsrj-10	15	154	to	to	PART
gsrj-10	15	155	stop	stop	VERB
gsrj-10	15	156	,	,	PUNCT
gsrj-10	15	157	and	and	CCONJ
gsrj-10	15	158	smokers	smoker	NOUN
gsrj-10	15	159	have	have	VERB
gsrj-10	15	160	a	a	DET
gsrj-10	15	161	higher	high	ADJ
gsrj-10	15	162	chance	chance	NOUN
gsrj-10	15	163	of	of	ADP
gsrj-10	15	164	becoming	become	VERB
gsrj-10	15	165	depressed	depressed	ADJ
gsrj-10	15	166	at	at	ADP
gsrj-10	15	167	some	some	DET
gsrj-10	15	168	point	point	NOUN
gsrj-10	15	169	in	in	ADP
gsrj-10	15	170	their	their	PRON
gsrj-10	15	171	lifetimes	lifetime	NOUN
gsrj-10	15	172	than	than	ADP
gsrj-10	15	173	non	non	ADJ
gsrj-10	15	174	-	-	NOUN
gsrj-10	15	175	smokers.5	smokers.5	ADV
gsrj-10	15	176	this	this	DET
gsrj-10	15	177	pattern	pattern	NOUN
gsrj-10	15	178	seems	seem	VERB
gsrj-10	15	179	to	to	PART
gsrj-10	15	180	follow	follow	VERB
gsrj-10	15	181	for	for	ADP
gsrj-10	15	182	other	other	ADJ
gsrj-10	15	183	drugs	drug	NOUN
gsrj-10	15	184	of	of	ADP
gsrj-10	15	185	abuse	abuse	NOUN
gsrj-10	15	186	as	as	ADV
gsrj-10	15	187	well	well	ADV
gsrj-10	15	188	,	,	PUNCT
gsrj-10	15	189	as	as	SCONJ
gsrj-10	15	190	it	it	PRON
gsrj-10	15	191	has	have	AUX
gsrj-10	15	192	been	be	AUX
gsrj-10	15	193	reported	report	VERB
gsrj-10	15	194	in	in	ADP
gsrj-10	15	195	both	both	CCONJ
gsrj-10	15	196	human	human	ADJ
gsrj-10	15	197	and	and	CCONJ
gsrj-10	15	198	animal	animal	NOUN
gsrj-10	15	199	studies	study	NOUN
gsrj-10	15	200	that	that	PRON
gsrj-10	15	201	stress	stress	NOUN
gsrj-10	15	202	is	be	AUX
gsrj-10	15	203	sufficient	sufficient	ADJ
gsrj-10	15	204	enough	enough	ADV
gsrj-10	15	205	to	to	PART
gsrj-10	15	206	significantly	significantly	ADV
gsrj-10	15	207	increase	increase	VERB
gsrj-10	15	208	the	the	DET
gsrj-10	15	209	likelihood	likelihood	NOUN
gsrj-10	15	210	of	of	ADP
gsrj-10	15	211	drug	drug	NOUN
gsrj-10	15	212	self	self	NOUN
gsrj-10	15	213	-	-	PUNCT
gsrj-10	15	214	administration	administration	NOUN
gsrj-10	15	215	and/or	and/or	CCONJ
gsrj-10	15	216	relapse	relapse	NOUN
gsrj-10	15	217	following	follow	VERB
gsrj-10	15	218	a	a	DET
gsrj-10	15	219	period	period	NOUN
gsrj-10	15	220	of	of	ADP
gsrj-10	15	221	abstinence	abstinence	NOUN
gsrj-10	15	222	from	from	ADP
gsrj-10	15	223	the	the	DET
gsrj-10	15	224	drug.6	drug.6	NOUN
gsrj-10	15	225	the	the	DET
gsrj-10	15	226	difficulty	difficulty	NOUN
gsrj-10	15	227	that	that	PRON
gsrj-10	15	228	many	many	ADJ
gsrj-10	15	229	face	face	NOUN
gsrj-10	15	230	in	in	ADP
gsrj-10	15	231	trying	try	VERB
gsrj-10	15	232	to	to	PART
gsrj-10	15	233	quit	quit	VERB
gsrj-10	15	234	using	use	VERB
gsrj-10	15	235	tobacco	tobacco	NOUN
gsrj-10	15	236	products	product	NOUN
gsrj-10	15	237	and	and	CCONJ
gsrj-10	15	238	the	the	DET
gsrj-10	15	239	comorbidity	comorbidity	NOUN
gsrj-10	15	240	between	between	ADP
gsrj-10	15	241	stress	stress	NOUN
gsrj-10	15	242	disorders	disorder	NOUN
gsrj-10	15	243	and	and	CCONJ
gsrj-10	15	244	nicotine	nicotine	ADJ
gsrj-10	15	245	dependence	dependence	NOUN
gsrj-10	15	246	can	can	AUX
gsrj-10	15	247	be	be	AUX
gsrj-10	15	248	explained	explain	VERB
gsrj-10	15	249	in	in	ADP
gsrj-10	15	250	part	part	NOUN
gsrj-10	15	251	by	by	ADP
gsrj-10	15	252	the	the	DET
gsrj-10	15	253	biological	biological	ADJ
gsrj-10	15	254	effects	effect	NOUN
gsrj-10	15	255	nicotine	nicotine	VERB
gsrj-10	15	256	and	and	CCONJ
gsrj-10	15	257	stress	stress	NOUN
gsrj-10	15	258	have	have	VERB
gsrj-10	15	259	on	on	ADP
gsrj-10	15	260	certain	certain	ADJ
gsrj-10	15	261	areas	area	NOUN
gsrj-10	15	262	of	of	ADP
gsrj-10	15	263	the	the	DET
gsrj-10	15	264	brain	brain	NOUN
gsrj-10	15	265	,	,	PUNCT
gsrj-10	15	266	particularly	particularly	ADV
gsrj-10	15	267	in	in	ADP
gsrj-10	15	268	the	the	DET
gsrj-10	15	269	reward	reward	NOUN
gsrj-10	15	270	pathway	pathway	NOUN
gsrj-10	15	271	.	.	PUNCT
gsrj-10	16	1	the	the	DET
gsrj-10	16	2	brain	brain	NOUN
gsrj-10	16	3	’s	’s	PART
gsrj-10	16	4	reward	reward	NOUN
gsrj-10	16	5	pathway	pathway	NOUN
gsrj-10	16	6	the	the	DET
gsrj-10	16	7	dopaminergic	dopaminergic	ADJ
gsrj-10	16	8	mesolimbic	mesolimbic	ADJ
gsrj-10	16	9	system	system	NOUN
gsrj-10	16	10	typically	typically	ADV
gsrj-10	16	11	functions	function	VERB
gsrj-10	16	12	to	to	PART
gsrj-10	16	13	reinforce	reinforce	VERB
gsrj-10	16	14	survival	survival	NOUN
gsrj-10	16	15	-	-	PUNCT
gsrj-10	16	16	promoting	promote	VERB
gsrj-10	16	17	behaviors	behavior	NOUN
gsrj-10	16	18	,	,	PUNCT
gsrj-10	16	19	such	such	ADJ
gsrj-10	16	20	as	as	ADP
gsrj-10	16	21	eating	eat	VERB
gsrj-10	16	22	,	,	PUNCT
gsrj-10	16	23	or	or	CCONJ
gsrj-10	16	24	positive	positive	ADJ
gsrj-10	16	25	social	social	ADJ
gsrj-10	16	26	interactions	interaction	NOUN
gsrj-10	16	27	,	,	PUNCT
gsrj-10	16	28	producing	produce	VERB
gsrj-10	16	29	positive	positive	ADJ
gsrj-10	16	30	feelings	feeling	NOUN
gsrj-10	16	31	,	,	PUNCT
gsrj-10	16	32	and	and	CCONJ
gsrj-10	16	33	serving	serve	VERB
gsrj-10	16	34	to	to	PART
gsrj-10	16	35	motivate	motivate	VERB
gsrj-10	16	36	such	such	ADJ
gsrj-10	16	37	behavior.7	behavior.7	ADJ
gsrj-10	16	38	drugs	drug	NOUN
gsrj-10	16	39	of	of	ADP
gsrj-10	16	40	addiction	addiction	NOUN
gsrj-10	16	41	,	,	PUNCT
gsrj-10	16	42	however	however	ADV
gsrj-10	16	43	,	,	PUNCT
gsrj-10	16	44	act	act	VERB
gsrj-10	16	45	on	on	ADP
gsrj-10	16	46	the	the	DET
gsrj-10	16	47	same	same	ADJ
gsrj-10	16	48	pathways	pathway	NOUN
gsrj-10	16	49	to	to	PART
gsrj-10	16	50	produce	produce	VERB
gsrj-10	16	51	their	their	PRON
gsrj-10	16	52	characteristic	characteristic	ADJ
gsrj-10	16	53	“	"	PUNCT
gsrj-10	16	54	high	high	ADJ
gsrj-10	16	55	”	"	PUNCT
gsrj-10	16	56	and	and	CCONJ
gsrj-10	16	57	reinforce	reinforce	VERB
gsrj-10	16	58	drug	drug	NOUN
gsrj-10	16	59	seeking	seeking	NOUN
gsrj-10	16	60	-	-	NOUN
gsrj-10	16	61	behaviors	behavior	NOUN
gsrj-10	16	62	and	and	CCONJ
gsrj-10	16	63	dependence.7	dependence.7	PROPN
gsrj-10	16	64	nicotine	nicotine	NOUN
gsrj-10	16	65	,	,	PUNCT
gsrj-10	16	66	for	for	ADP
gsrj-10	16	67	example	example	NOUN
gsrj-10	16	68	,	,	PUNCT
gsrj-10	16	69	is	be	AUX
gsrj-10	16	70	an	an	DET
gsrj-10	16	71	agonist	agonist	NOUN
gsrj-10	16	72	of	of	ADP
gsrj-10	16	73	the	the	DET
gsrj-10	16	74	endogenous	endogenous	ADJ
gsrj-10	16	75	neuronal	neuronal	ADJ
gsrj-10	16	76	nicotinic	nicotinic	ADJ
gsrj-10	16	77	acetylcholine	acetylcholine	NOUN
gsrj-10	16	78	receptor	receptor	NOUN
gsrj-10	16	79	(	(	PUNCT
gsrj-10	16	80	nachr	nachr	PROPN
gsrj-10	16	81	)	)	PUNCT
gsrj-10	16	82	,	,	PUNCT
gsrj-10	16	83	an	an	DET
gsrj-10	16	84	ionotropic	ionotropic	ADJ
gsrj-10	16	85	receptor	receptor	NOUN
gsrj-10	16	86	type	type	NOUN
gsrj-10	16	87	found	find	VERB
gsrj-10	16	88	widely	widely	ADV
gsrj-10	16	89	dispersed	disperse	VERB
gsrj-10	16	90	throughout	throughout	ADP
gsrj-10	16	91	the	the	DET
gsrj-10	16	92	cns	cns	NOUN
gsrj-10	16	93	.	.	PROPN
gsrj-10	17	1	nachrs	nachrs	PROPN
gsrj-10	17	2	have	have	AUX
gsrj-10	17	3	been	be	AUX
gsrj-10	17	4	found	find	VERB
gsrj-10	17	5	to	to	PART
gsrj-10	17	6	be	be	AUX
gsrj-10	17	7	critical	critical	ADJ
gsrj-10	17	8	in	in	ADP
gsrj-10	17	9	the	the	DET
gsrj-10	17	10	modulation	modulation	NOUN
gsrj-10	17	11	of	of	ADP
gsrj-10	17	12	dopaminergic	dopaminergic	ADJ
gsrj-10	17	13	activity	activity	NOUN
gsrj-10	17	14	throughout	throughout	ADP
gsrj-10	17	15	the	the	DET
gsrj-10	17	16	mesolimbic	mesolimbic	NOUN
gsrj-10	17	17	system.8	system.8	CCONJ
gsrj-10	17	18	several	several	ADJ
gsrj-10	17	19	brain	brain	NOUN
gsrj-10	17	20	regions	region	NOUN
gsrj-10	17	21	have	have	AUX
gsrj-10	17	22	been	be	AUX
gsrj-10	17	23	linked	link	VERB
gsrj-10	17	24	to	to	ADP
gsrj-10	17	25	the	the	DET
gsrj-10	17	26	encoding	encoding	NOUN
gsrj-10	17	27	of	of	ADP
gsrj-10	17	28	reward	reward	NOUN
gsrj-10	17	29	-	-	PUNCT
gsrj-10	17	30	related	relate	VERB
gsrj-10	17	31	behaviors	behavior	NOUN
gsrj-10	17	32	,	,	PUNCT
gsrj-10	17	33	including	include	VERB
gsrj-10	17	34	the	the	DET
gsrj-10	17	35	nucleus	nucleus	NOUN
gsrj-10	17	36	accumbens	accumben	NOUN
gsrj-10	17	37	(	(	PUNCT
gsrj-10	17	38	nac	nac	PROPN
gsrj-10	17	39	)	)	PUNCT
gsrj-10	17	40	,	,	PUNCT
gsrj-10	17	41	ventral	ventral	ADJ
gsrj-10	17	42	tegmental	tegmental	ADJ
gsrj-10	17	43	area	area	NOUN
gsrj-10	17	44	(	(	PUNCT
gsrj-10	17	45	vta	vta	PROPN
gsrj-10	17	46	)	)	PUNCT
gsrj-10	17	47	,	,	PUNCT
gsrj-10	17	48	amygdala	amygdala	NOUN
gsrj-10	17	49	,	,	PUNCT
gsrj-10	17	50	and	and	CCONJ
gsrj-10	17	51	hypothalamus	hypothalamus	PROPN
gsrj-10	17	52	,	,	PUNCT
gsrj-10	17	53	with	with	ADP
gsrj-10	17	54	a	a	DET
gsrj-10	17	55	particular	particular	ADJ
gsrj-10	17	56	emphasis	emphasis	NOUN
gsrj-10	17	57	on	on	ADP
gsrj-10	17	58	the	the	DET
gsrj-10	17	59	dopaminergic	dopaminergic	ADJ
gsrj-10	17	60	projections	projection	NOUN
gsrj-10	17	61	from	from	ADP
gsrj-10	17	62	the	the	DET
gsrj-10	17	63	vta	vta	PROPN
gsrj-10	17	64	to	to	ADP
gsrj-10	17	65	nac	nac	PROPN
gsrj-10	17	66	.	.	PUNCT
gsrj-10	18	1	the	the	DET
gsrj-10	18	2	vta	vta	PROPN
gsrj-10	18	3	and	and	CCONJ
gsrj-10	18	4	nac	nac	PROPN
gsrj-10	18	5	are	be	AUX
gsrj-10	18	6	strongly	strongly	ADV
gsrj-10	18	7	implicated	implicate	VERB
gsrj-10	18	8	in	in	ADP
gsrj-10	18	9	both	both	PRON
gsrj-10	18	10	nicotine	nicotine	ADJ
gsrj-10	18	11	addiction	addiction	NOUN
gsrj-10	18	12	and	and	CCONJ
gsrj-10	18	13	many	many	ADJ
gsrj-10	18	14	stress	stress	NOUN
gsrj-10	18	15	and	and	CCONJ
gsrj-10	18	16	mood	mood	NOUN
gsrj-10	18	17	disorders.5	disorders.5	PROPN
gsrj-10	18	18	,	,	PUNCT
gsrj-10	18	19	9	9	NUM
gsrj-10	18	20	the	the	DET
gsrj-10	18	21	variety	variety	NOUN
gsrj-10	18	22	of	of	ADP
gsrj-10	18	23	inputs	input	NOUN
gsrj-10	18	24	that	that	PRON
gsrj-10	18	25	both	both	CCONJ
gsrj-10	18	26	the	the	DET
gsrj-10	18	27	vta	vta	PROPN
gsrj-10	18	28	and	and	CCONJ
gsrj-10	18	29	nac	nac	PROPN
gsrj-10	18	30	receive	receive	VERB
gsrj-10	18	31	glutamatergic	glutamatergic	ADJ
gsrj-10	18	32	,	,	PUNCT
gsrj-10	18	33	cholinergic	cholinergic	ADJ
gsrj-10	18	34	,	,	PUNCT
gsrj-10	18	35	peptidergic	peptidergic	NOUN
gsrj-10	18	36	,	,	PUNCT
gsrj-10	18	37	and	and	CCONJ
gsrj-10	18	38	serotonergic	serotonergic	ADJ
gsrj-10	18	39	function	function	NOUN
gsrj-10	18	40	to	to	PART
gsrj-10	18	41	modulate	modulate	VERB
gsrj-10	18	42	dopaminergic	dopaminergic	ADJ
gsrj-10	18	43	neuron	neuron	NOUN
gsrj-10	18	44	firing	fire	VERB
gsrj-10	18	45	between	between	ADP
gsrj-10	18	46	the	the	DET
gsrj-10	18	47	vta	vta	PROPN
gsrj-10	18	48	and	and	CCONJ
gsrj-10	18	49	nac	nac	PROPN
gsrj-10	18	50	(	(	PUNCT
gsrj-10	18	51	figure	figure	VERB
gsrj-10	18	52	1).10	1).10	NOUN
gsrj-10	18	53	at	at	ADP
gsrj-10	18	54	the	the	DET
gsrj-10	18	55	core	core	NOUN
gsrj-10	18	56	of	of	ADP
gsrj-10	18	57	encoding	encode	VERB
gsrj-10	18	58	rewardrelated	rewardrelate	VERB
gsrj-10	18	59	behaviors	behavior	NOUN
gsrj-10	18	60	in	in	ADP
gsrj-10	18	61	these	these	DET
gsrj-10	18	62	two	two	NUM
gsrj-10	18	63	regions	region	NOUN
gsrj-10	18	64	are	be	AUX
gsrj-10	18	65	the	the	DET
gsrj-10	18	66	distinct	distinct	ADJ
gsrj-10	18	67	modes	mode	NOUN
gsrj-10	18	68	of	of	ADP
gsrj-10	18	69	the	the	DET
gsrj-10	18	70	firing	firing	NOUN
gsrj-10	18	71	of	of	ADP
gsrj-10	18	72	the	the	DET
gsrj-10	18	73	vta	vta	PROPN
gsrj-10	18	74	dopaminergic	dopaminergic	ADJ
gsrj-10	18	75	neurons	neuron	NOUN
gsrj-10	18	76	innervating	innervate	VERB
gsrj-10	18	77	the	the	DET
gsrj-10	18	78	nac	nac	NOUN
gsrj-10	18	79	:	:	PUNCT
gsrj-10	18	80	tonic	tonic	NOUN
gsrj-10	18	81	and	and	CCONJ
gsrj-10	18	82	phasic	phasic	NOUN
gsrj-10	18	83	.	.	PUNCT
gsrj-10	19	1	tonic	tonic	NOUN
gsrj-10	19	2	firing	firing	NOUN
gsrj-10	19	3	is	be	AUX
gsrj-10	19	4	low	low	ADJ
gsrj-10	19	5	-	-	PUNCT
gsrj-10	19	6	frequency	frequency	NOUN
gsrj-10	19	7	and	and	CCONJ
gsrj-10	19	8	regular	regular	ADJ
gsrj-10	19	9	,	,	PUNCT
gsrj-10	19	10	whereas	whereas	SCONJ
gsrj-10	19	11	the	the	DET
gsrj-10	19	12	phasic	phasic	ADJ
gsrj-10	19	13	mode	mode	NOUN
gsrj-10	19	14	is	be	AUX
gsrj-10	19	15	characterized	characterize	VERB
gsrj-10	19	16	by	by	ADP
gsrj-10	19	17	high	high	ADJ
gsrj-10	19	18	-	-	PUNCT
gsrj-10	19	19	frequency	frequency	NOUN
gsrj-10	19	20	bursts	burst	NOUN
gsrj-10	19	21	of	of	ADP
gsrj-10	19	22	firing	fire	VERB
gsrj-10	19	23	.	.	PUNCT
gsrj-10	20	1	cholinergic	cholinergic	ADJ
gsrj-10	20	2	signaling	signal	VERB
gsrj-10	20	3	especially	especially	ADV
gsrj-10	20	4	as	as	SCONJ
gsrj-10	20	5	mediated	mediate	VERB
gsrj-10	20	6	by	by	ADP
gsrj-10	20	7	nachrs	nachrs	ADJ
gsrj-10	20	8	is	be	AUX
gsrj-10	20	9	critical	critical	ADJ
gsrj-10	20	10	in	in	ADP
gsrj-10	20	11	facilitating	facilitate	VERB
gsrj-10	20	12	the	the	DET
gsrj-10	20	13	switch	switch	NOUN
gsrj-10	20	14	between	between	ADP
gsrj-10	20	15	vta	vta	PROPN
gsrj-10	20	16	neurons	neuron	NOUN
gsrj-10	20	17	’	'	PUNCT
gsrj-10	20	18	tonic	tonic	NOUN
gsrj-10	20	19	and	and	CCONJ
gsrj-10	20	20	phasic	phasic	NOUN
gsrj-10	20	21	modes	mode	NOUN
gsrj-10	20	22	and	and	CCONJ
gsrj-10	20	23	,	,	PUNCT
gsrj-10	20	24	therefore	therefore	ADV
gsrj-10	20	25	,	,	PUNCT
gsrj-10	20	26	in	in	ADP
gsrj-10	20	27	encoding	encode	VERB
gsrj-10	20	28	reward	reward	NOUN
gsrj-10	20	29	-	-	PUNCT
gsrj-10	20	30	related	relate	VERB
gsrj-10	20	31	information	information	NOUN
gsrj-10	20	32	and	and	CCONJ
gsrj-10	20	33	behaviors.10	behaviors.10	VERB
gsrj-10	20	34	further	far	ADV
gsrj-10	20	35	,	,	PUNCT
gsrj-10	20	36	both	both	PRON
gsrj-10	20	37	stress	stress	NOUN
gsrj-10	20	38	and	and	CCONJ
gsrj-10	20	39	drug	drug	NOUN
gsrj-10	20	40	addiction	addiction	NOUN
gsrj-10	20	41	have	have	AUX
gsrj-10	20	42	been	be	AUX
gsrj-10	20	43	reliably	reliably	ADV
gsrj-10	20	44	shown	show	VERB
gsrj-10	20	45	to	to	PART
gsrj-10	20	46	be	be	AUX
gsrj-10	20	47	key	key	ADJ
gsrj-10	20	48	in	in	ADP
gsrj-10	20	49	determining	determine	VERB
gsrj-10	20	50	the	the	DET
gsrj-10	20	51	basal	basal	NOUN
gsrj-10	20	52	firing	firing	NOUN
gsrj-10	20	53	rate	rate	NOUN
gsrj-10	20	54	for	for	ADP
gsrj-10	20	55	dopaminergic	dopaminergic	ADJ
gsrj-10	20	56	neurons.10	neurons.10	NOUN
gsrj-10	20	57	combined	combine	VERB
gsrj-10	20	58	,	,	PUNCT
gsrj-10	20	59	this	this	DET
gsrj-10	20	60	evidence	evidence	NOUN
gsrj-10	20	61	points	point	VERB
gsrj-10	20	62	toward	toward	ADP
gsrj-10	20	63	an	an	DET
gsrj-10	20	64	important	important	ADJ
gsrj-10	20	65	connection	connection	NOUN
gsrj-10	20	66	between	between	ADP
gsrj-10	20	67	stress	stress	NOUN
gsrj-10	20	68	,	,	PUNCT
gsrj-10	20	69	addiction	addiction	NOUN
gsrj-10	20	70	,	,	PUNCT
gsrj-10	20	71	and	and	CCONJ
gsrj-10	20	72	cholinergic	cholinergic	NOUN
gsrj-10	20	73	signaling	signal	VERB
gsrj-10	20	74	in	in	ADP
gsrj-10	20	75	the	the	DET
gsrj-10	20	76	dopaminergic	dopaminergic	ADJ
gsrj-10	20	77	mesolimbic	mesolimbic	ADJ
gsrj-10	20	78	system	system	NOUN
gsrj-10	20	79	.	.	PUNCT
gsrj-10	21	1	72	72	NUM
gsrj-10	21	2	georgetown	georgetown	PROPN
gsrj-10	21	3	scientific	scientific	PROPN
gsrj-10	21	4	research	research	PROPN
gsrj-10	21	5	journal	journal	PROPN
gsrj-10	21	6	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	ADJ
gsrj-10	21	7	figure	figure	NOUN
gsrj-10	21	8	1	1	NUM
gsrj-10	21	9	.	.	PUNCT
gsrj-10	22	1	a	a	DET
gsrj-10	22	2	variety	variety	NOUN
gsrj-10	22	3	of	of	ADP
gsrj-10	22	4	complex	complex	ADJ
gsrj-10	22	5	neural	neural	ADJ
gsrj-10	22	6	inputs	input	NOUN
gsrj-10	22	7	modulate	modulate	VERB
gsrj-10	22	8	dopaminergic	dopaminergic	ADJ
gsrj-10	22	9	signaling	signal	VERB
gsrj-10	22	10	from	from	ADP
gsrj-10	22	11	the	the	DET
gsrj-10	22	12	ventral	ventral	ADJ
gsrj-10	22	13	tegmental	tegmental	ADJ
gsrj-10	22	14	area	area	NOUN
gsrj-10	22	15	(	(	PUNCT
gsrj-10	22	16	vta	vta	PROPN
gsrj-10	22	17	)	)	PUNCT
gsrj-10	22	18	to	to	ADP
gsrj-10	22	19	the	the	DET
gsrj-10	22	20	nucleus	nucleus	NOUN
gsrj-10	22	21	accumbens	accumben	NOUN
gsrj-10	22	22	(	(	PUNCT
gsrj-10	22	23	nac	nac	PROPN
gsrj-10	22	24	)	)	PUNCT
gsrj-10	22	25	.	.	PUNCT
gsrj-10	23	1	the	the	DET
gsrj-10	23	2	illustration	illustration	NOUN
gsrj-10	23	3	above	above	ADV
gsrj-10	23	4	shows	show	VERB
gsrj-10	23	5	a	a	DET
gsrj-10	23	6	simplified	simplified	ADJ
gsrj-10	23	7	summary	summary	NOUN
gsrj-10	23	8	of	of	ADP
gsrj-10	23	9	several	several	ADJ
gsrj-10	23	10	well	well	ADV
gsrj-10	23	11	-	-	PUNCT
gsrj-10	23	12	established	establish	VERB
gsrj-10	23	13	circuits	circuit	NOUN
gsrj-10	23	14	that	that	PRON
gsrj-10	23	15	influence	influence	VERB
gsrj-10	23	16	mood	mood	NOUN
gsrj-10	23	17	and	and	CCONJ
gsrj-10	23	18	have	have	AUX
gsrj-10	23	19	been	be	AUX
gsrj-10	23	20	implicated	implicate	VERB
gsrj-10	23	21	in	in	ADP
gsrj-10	23	22	the	the	DET
gsrj-10	23	23	dysregulation	dysregulation	NOUN
gsrj-10	23	24	of	of	ADP
gsrj-10	23	25	mood	mood	NOUN
gsrj-10	23	26	.	.	PUNCT
gsrj-10	24	1	glutamatergic	glutamatergic	ADJ
gsrj-10	24	2	areas	area	NOUN
gsrj-10	24	3	include	include	VERB
gsrj-10	24	4	the	the	DET
gsrj-10	24	5	prefrontal	prefrontal	ADJ
gsrj-10	24	6	cortex	cortex	NOUN
gsrj-10	24	7	(	(	PUNCT
gsrj-10	24	8	pfc	pfc	NOUN
gsrj-10	24	9	)	)	PUNCT
gsrj-10	24	10	,	,	PUNCT
gsrj-10	24	11	hippocampus	hippocampus	NOUN
gsrj-10	24	12	(	(	PUNCT
gsrj-10	24	13	hp	hp	NOUN
gsrj-10	24	14	)	)	PUNCT
gsrj-10	24	15	,	,	PUNCT
gsrj-10	24	16	and	and	CCONJ
gsrj-10	24	17	amygdala	amygdala	NOUN
gsrj-10	24	18	(	(	PUNCT
gsrj-10	24	19	amy	amy	PROPN
gsrj-10	24	20	)	)	PUNCT
gsrj-10	24	21	,	,	PUNCT
gsrj-10	24	22	where	where	SCONJ
gsrj-10	24	23	the	the	DET
gsrj-10	24	24	dorsal	dorsal	NOUN
gsrj-10	24	25	raphe	raphe	NOUN
gsrj-10	24	26	/	/	SYM
gsrj-10	24	27	locus	locus	NOUN
gsrj-10	24	28	coeruleus	coeruleus	NOUN
gsrj-10	24	29	(	(	PUNCT
gsrj-10	24	30	dr	dr	PROPN
gsrj-10	24	31	/	/	SYM
gsrj-10	24	32	lc	lc	PROPN
gsrj-10	24	33	)	)	PUNCT
gsrj-10	24	34	mainly	mainly	ADV
gsrj-10	24	35	transmit	transmit	VERB
gsrj-10	24	36	serotonin	serotonin	NOUN
gsrj-10	24	37	and	and	CCONJ
gsrj-10	24	38	norepinephrine	norepinephrine	NOUN
gsrj-10	24	39	(	(	PUNCT
gsrj-10	24	40	5ht	5ht	NOUN
gsrj-10	24	41	,	,	PUNCT
gsrj-10	24	42	ne	ne	PROPN
gsrj-10	24	43	)	)	PUNCT
gsrj-10	24	44	.	.	PUNCT
gsrj-10	25	1	the	the	DET
gsrj-10	25	2	hypothalamus	hypothalamus	PROPN
gsrj-10	25	3	(	(	PUNCT
gsrj-10	25	4	hypo	hypo	PROPN
gsrj-10	25	5	)	)	PUNCT
gsrj-10	25	6	also	also	ADV
gsrj-10	25	7	influences	influence	VERB
gsrj-10	25	8	the	the	DET
gsrj-10	25	9	vta	vta	PROPN
gsrj-10	25	10	and	and	CCONJ
gsrj-10	25	11	nac	nac	PROPN
gsrj-10	25	12	with	with	ADP
gsrj-10	25	13	peptidergic	peptidergic	NOUN
gsrj-10	25	14	inputs	input	NOUN
gsrj-10	25	15	.	.	PUNCT
gsrj-10	26	1	(	(	PUNCT
gsrj-10	26	2	figure	figure	NOUN
gsrj-10	26	3	taken	take	VERB
gsrj-10	26	4	from	from	ADP
gsrj-10	26	5	nestler	nestler	NOUN
gsrj-10	26	6	and	and	CCONJ
gsrj-10	26	7	carlezon	carlezon	NOUN
gsrj-10	26	8	,	,	PUNCT
gsrj-10	26	9	2006	2006	NUM
gsrj-10	26	10	)	)	PUNCT
gsrj-10	26	11	.	.	PUNCT
gsrj-10	27	1	like	like	ADP
gsrj-10	27	2	all	all	DET
gsrj-10	27	3	complex	complex	ADJ
gsrj-10	27	4	neural	neural	ADJ
gsrj-10	27	5	systems	system	NOUN
gsrj-10	27	6	,	,	PUNCT
gsrj-10	27	7	the	the	DET
gsrj-10	27	8	ability	ability	NOUN
gsrj-10	27	9	of	of	ADP
gsrj-10	27	10	the	the	DET
gsrj-10	27	11	mesolimbic	mesolimbic	ADJ
gsrj-10	27	12	system	system	NOUN
gsrj-10	27	13	to	to	PART
gsrj-10	27	14	encode	encode	VERB
gsrj-10	27	15	nuanced	nuanced	ADJ
gsrj-10	27	16	information	information	NOUN
gsrj-10	27	17	relies	rely	VERB
gsrj-10	27	18	on	on	ADP
gsrj-10	27	19	the	the	DET
gsrj-10	27	20	amount	amount	NOUN
gsrj-10	27	21	and	and	CCONJ
gsrj-10	27	22	type	type	NOUN
gsrj-10	27	23	of	of	ADP
gsrj-10	27	24	afferent	afferent	ADJ
gsrj-10	27	25	input	input	NOUN
gsrj-10	27	26	it	it	PRON
gsrj-10	27	27	receives	receive	VERB
gsrj-10	27	28	.	.	PUNCT
gsrj-10	28	1	nachr	nachr	PROPN
gsrj-10	28	2	subtypes	subtype	NOUN
gsrj-10	28	3	are	be	AUX
gsrj-10	28	4	differentially	differentially	ADV
gsrj-10	28	5	expressed	express	VERB
gsrj-10	28	6	on	on	ADP
gsrj-10	28	7	different	different	ADJ
gsrj-10	28	8	types	type	NOUN
gsrj-10	28	9	of	of	ADP
gsrj-10	28	10	neurons	neuron	NOUN
gsrj-10	28	11	throughout	throughout	ADP
gsrj-10	28	12	the	the	DET
gsrj-10	28	13	vta	vta	PROPN
gsrj-10	28	14	and	and	CCONJ
gsrj-10	28	15	nac	nac	PROPN
gsrj-10	28	16	;	;	PUNCT
gsrj-10	28	17	depending	depend	VERB
gsrj-10	28	18	on	on	ADP
gsrj-10	28	19	the	the	DET
gsrj-10	28	20	subunit	subunit	NOUN
gsrj-10	28	21	composition	composition	NOUN
gsrj-10	28	22	of	of	ADP
gsrj-10	28	23	the	the	DET
gsrj-10	28	24	receptor	receptor	NOUN
gsrj-10	28	25	,	,	PUNCT
gsrj-10	28	26	its	its	PRON
gsrj-10	28	27	affinity	affinity	NOUN
gsrj-10	28	28	for	for	ADP
gsrj-10	28	29	endogenous	endogenous	ADJ
gsrj-10	28	30	or	or	CCONJ
gsrj-10	28	31	pharmacological	pharmacological	ADJ
gsrj-10	28	32	agonists	agonist	NOUN
gsrj-10	28	33	varies	vary	VERB
gsrj-10	28	34	.	.	PUNCT
gsrj-10	29	1	these	these	DET
gsrj-10	29	2	receptors	receptor	NOUN
gsrj-10	29	3	’	'	PUNCT
gsrj-10	29	4	unique	unique	ADJ
gsrj-10	29	5	expression	expression	NOUN
gsrj-10	29	6	patterns	pattern	NOUN
gsrj-10	29	7	lend	lend	VERB
gsrj-10	29	8	each	each	DET
gsrj-10	29	9	region	region	NOUN
gsrj-10	29	10	the	the	DET
gsrj-10	29	11	ability	ability	NOUN
gsrj-10	29	12	to	to	PART
gsrj-10	29	13	integrate	integrate	VERB
gsrj-10	29	14	a	a	DET
gsrj-10	29	15	variety	variety	NOUN
gsrj-10	29	16	of	of	ADP
gsrj-10	29	17	signals	signal	NOUN
gsrj-10	29	18	and	and	CCONJ
gsrj-10	29	19	encode	encode	ADJ
gsrj-10	29	20	complex	complex	ADJ
gsrj-10	29	21	behaviors	behavior	NOUN
gsrj-10	29	22	and	and	CCONJ
gsrj-10	29	23	are	be	AUX
gsrj-10	29	24	differentially	differentially	ADV
gsrj-10	29	25	implicated	implicate	VERB
gsrj-10	29	26	in	in	ADP
gsrj-10	29	27	the	the	DET
gsrj-10	29	28	pathology	pathology	NOUN
gsrj-10	29	29	of	of	ADP
gsrj-10	29	30	both	both	DET
gsrj-10	29	31	nicotine	nicotine	ADJ
gsrj-10	29	32	dependence	dependence	NOUN
gsrj-10	29	33	and	and	CCONJ
gsrj-10	29	34	stress	stress	NOUN
gsrj-10	29	35	.	.	PUNCT
gsrj-10	30	1	this	this	DET
gsrj-10	30	2	paper	paper	NOUN
gsrj-10	30	3	explores	explore	VERB
gsrj-10	30	4	these	these	DET
gsrj-10	30	5	cholinergic	cholinergic	ADJ
gsrj-10	30	6	influences	influence	NOUN
gsrj-10	30	7	in	in	ADP
gsrj-10	30	8	the	the	DET
gsrj-10	30	9	mesolimbic	mesolimbic	ADJ
gsrj-10	30	10	system	system	NOUN
gsrj-10	30	11	and	and	CCONJ
gsrj-10	30	12	the	the	DET
gsrj-10	30	13	convergence	convergence	NOUN
gsrj-10	30	14	and	and	CCONJ
gsrj-10	30	15	divergence	divergence	NOUN
gsrj-10	30	16	of	of	ADP
gsrj-10	30	17	the	the	DET
gsrj-10	30	18	pathologies	pathology	NOUN
gsrj-10	30	19	of	of	ADP
gsrj-10	30	20	nicotine	nicotine	NOUN
gsrj-10	30	21	and	and	CCONJ
gsrj-10	30	22	stress	stress	NOUN
gsrj-10	30	23	,	,	PUNCT
gsrj-10	30	24	implicating	implicate	VERB
gsrj-10	30	25	mechanisms	mechanism	NOUN
gsrj-10	30	26	of	of	ADP
gsrj-10	30	27	long	long	ADJ
gsrj-10	30	28	-	-	PUNCT
gsrj-10	30	29	term	term	NOUN
gsrj-10	30	30	potentiation	potentiation	NOUN
gsrj-10	30	31	(	(	PUNCT
gsrj-10	30	32	ltp	ltp	NOUN
gsrj-10	30	33	)	)	PUNCT
gsrj-10	30	34	and	and	CCONJ
gsrj-10	30	35	exploring	explore	VERB
gsrj-10	30	36	potential	potential	ADJ
gsrj-10	30	37	therapeutic	therapeutic	ADJ
gsrj-10	30	38	targets	target	NOUN
gsrj-10	30	39	.	.	PUNCT
gsrj-10	31	1	2	2	X
gsrj-10	31	2	.	.	X
gsrj-10	31	3	nicotinic	nicotinic	ADJ
gsrj-10	31	4	receptors	receptor	NOUN
gsrj-10	31	5	and	and	CCONJ
gsrj-10	31	6	social	social	ADJ
gsrj-10	31	7	stress	stress	NOUN
gsrj-10	31	8	’	'	PUNCT
gsrj-10	31	9	role	role	NOUN
gsrj-10	31	10	on	on	ADP
gsrj-10	31	11	the	the	DET
gsrj-10	31	12	vta	vta	PROPN
gsrj-10	31	13	interestingly	interestingly	ADV
gsrj-10	31	14	,	,	PUNCT
gsrj-10	31	15	mood	mood	NOUN
gsrj-10	31	16	disorders	disorder	NOUN
gsrj-10	31	17	and	and	CCONJ
gsrj-10	31	18	social	social	ADJ
gsrj-10	31	19	stress	stress	NOUN
gsrj-10	31	20	have	have	AUX
gsrj-10	31	21	also	also	ADV
gsrj-10	31	22	been	be	AUX
gsrj-10	31	23	shown	show	VERB
gsrj-10	31	24	to	to	PART
gsrj-10	31	25	affect	affect	VERB
gsrj-10	31	26	dopaminergic	dopaminergic	ADJ
gsrj-10	31	27	signaling	signal	VERB
gsrj-10	31	28	in	in	ADP
gsrj-10	31	29	the	the	DET
gsrj-10	31	30	same	same	ADJ
gsrj-10	31	31	pathways.9	pathways.9	NOUN
gsrj-10	31	32	several	several	ADJ
gsrj-10	31	33	studies	study	NOUN
gsrj-10	31	34	have	have	AUX
gsrj-10	31	35	found	find	VERB
gsrj-10	31	36	that	that	SCONJ
gsrj-10	31	37	the	the	DET
gsrj-10	31	38	effects	effect	NOUN
gsrj-10	31	39	of	of	ADP
gsrj-10	31	40	nicotine	nicotine	NOUN
gsrj-10	31	41	use	use	NOUN
gsrj-10	31	42	and	and	CCONJ
gsrj-10	31	43	stress	stress	NOUN
gsrj-10	31	44	can	can	AUX
gsrj-10	31	45	exacerbate	exacerbate	VERB
gsrj-10	31	46	each	each	DET
gsrj-10	31	47	other	other	ADJ
gsrj-10	31	48	,	,	PUNCT
gsrj-10	31	49	independent	independent	ADJ
gsrj-10	31	50	of	of	ADP
gsrj-10	31	51	the	the	DET
gsrj-10	31	52	withdrawal	withdrawal	NOUN
gsrj-10	31	53	effects	effect	NOUN
gsrj-10	31	54	common	common	ADJ
gsrj-10	31	55	in	in	ADP
gsrj-10	31	56	nicotine	nicotine	NOUN
gsrj-10	31	57	addiction.12	addiction.12	NOUN
gsrj-10	31	58	morel	morel	PROPN
gsrj-10	31	59	et	et	PROPN
gsrj-10	31	60	al	al	PROPN
gsrj-10	31	61	.	.	PROPN
gsrj-10	31	62	,	,	PUNCT
gsrj-10	31	63	2018	2018	NUM
gsrj-10	31	64	found	find	VERB
gsrj-10	31	65	that	that	SCONJ
gsrj-10	31	66	this	this	DET
gsrj-10	31	67	bidirectional	bidirectional	ADJ
gsrj-10	31	68	relationship	relationship	NOUN
gsrj-10	31	69	between	between	ADP
gsrj-10	31	70	nicotine	nicotine	NOUN
gsrj-10	31	71	and	and	CCONJ
gsrj-10	31	72	stress	stress	NOUN
gsrj-10	31	73	is	be	AUX
gsrj-10	31	74	likely	likely	ADV
gsrj-10	31	75	mediated	mediate	VERB
gsrj-10	31	76	by	by	ADP
gsrj-10	31	77	dopaminergic	dopaminergic	ADJ
gsrj-10	31	78	(	(	PUNCT
gsrj-10	31	79	da	da	ADJ
gsrj-10	31	80	)	)	PUNCT
gsrj-10	31	81	vta	vta	PROPN
gsrj-10	31	82	neurons.5	neurons.5	NOUN
gsrj-10	31	83	because	because	SCONJ
gsrj-10	31	84	the	the	DET
gsrj-10	31	85	etiologies	etiology	NOUN
gsrj-10	31	86	of	of	ADP
gsrj-10	31	87	stressrelated	stressrelate	VERB
gsrj-10	31	88	and	and	CCONJ
gsrj-10	31	89	depressive	depressive	ADJ
gsrj-10	31	90	symptoms	symptom	NOUN
gsrj-10	31	91	are	be	AUX
gsrj-10	31	92	often	often	ADV
gsrj-10	31	93	quite	quite	ADV
gsrj-10	31	94	varied	varied	ADJ
gsrj-10	31	95	and	and	CCONJ
gsrj-10	31	96	complex	complex	ADJ
gsrj-10	31	97	,	,	PUNCT
gsrj-10	31	98	studying	study	VERB
gsrj-10	31	99	these	these	PRON
gsrj-10	31	100	in	in	ADP
gsrj-10	31	101	animal	animal	NOUN
gsrj-10	31	102	models	model	NOUN
gsrj-10	31	103	can	can	AUX
gsrj-10	31	104	pose	pose	VERB
gsrj-10	31	105	a	a	DET
gsrj-10	31	106	difficult	difficult	ADJ
gsrj-10	31	107	challenge	challenge	NOUN
gsrj-10	31	108	.	.	PUNCT
gsrj-10	32	1	both	both	PRON
gsrj-10	32	2	nicotine	nicotine	VERB
gsrj-10	32	3	exposure	exposure	NOUN
gsrj-10	32	4	and	and	CCONJ
gsrj-10	32	5	social	social	ADJ
gsrj-10	32	6	stress	stress	NOUN
gsrj-10	32	7	have	have	AUX
gsrj-10	32	8	been	be	AUX
gsrj-10	32	9	shown	show	VERB
gsrj-10	32	10	to	to	PART
gsrj-10	32	11	increase	increase	VERB
gsrj-10	32	12	the	the	DET
gsrj-10	32	13	frequency	frequency	NOUN
gsrj-10	32	14	and	and	CCONJ
gsrj-10	32	15	bursting	bursting	NOUN
gsrj-10	32	16	activity	activity	NOUN
gsrj-10	32	17	of	of	ADP
gsrj-10	32	18	vta	vta	PROPN
gsrj-10	32	19	da	da	PROPN
gsrj-10	32	20	neuron	neuron	PROPN
gsrj-10	32	21	firing.12	firing.12	NOUN
gsrj-10	32	22	interestingly	interestingly	ADV
gsrj-10	32	23	,	,	PUNCT
gsrj-10	32	24	this	this	DET
gsrj-10	32	25	study	study	NOUN
gsrj-10	32	26	found	find	VERB
gsrj-10	32	27	that	that	SCONJ
gsrj-10	32	28	the	the	DET
gsrj-10	32	29	effects	effect	NOUN
gsrj-10	32	30	of	of	ADP
gsrj-10	32	31	stress	stress	NOUN
gsrj-10	32	32	seem	seem	VERB
gsrj-10	32	33	to	to	PART
gsrj-10	32	34	depend	depend	VERB
gsrj-10	32	35	upon	upon	SCONJ
gsrj-10	32	36	the	the	DET
gsrj-10	32	37	same	same	ADJ
gsrj-10	32	38	nachrs	nachrs	NOUN
gsrj-10	32	39	that	that	SCONJ
gsrj-10	32	40	nicotine	nicotine	NOUN
gsrj-10	32	41	acts	act	VERB
gsrj-10	32	42	on	on	ADP
gsrj-10	32	43	.	.	PUNCT
gsrj-10	33	1	specifically	specifically	ADV
gsrj-10	33	2	,	,	PUNCT
gsrj-10	33	3	both	both	PRON
gsrj-10	33	4	nicotine	nicotine	VERB
gsrj-10	33	5	and	and	CCONJ
gsrj-10	33	6	stress	stress	NOUN
gsrj-10	33	7	interact	interact	NOUN
gsrj-10	33	8	with	with	ADP
gsrj-10	33	9	the	the	DET
gsrj-10	33	10	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	33	11	homomeric	homomeric	ADJ
gsrj-10	33	12	and	and	CCONJ
gsrj-10	33	13	2	2	NUM
gsrj-10	33	14	-	-	PUNCT
gsrj-10	33	15	containing	contain	VERB
gsrj-10	33	16	heteromeric	heteromeric	NOUN
gsrj-10	33	17	nachrs	nachrs	PROPN
gsrj-10	33	18	,	,	PUNCT
gsrj-10	33	19	the	the	DET
gsrj-10	33	20	two	two	NUM
gsrj-10	33	21	primary	primary	ADJ
gsrj-10	33	22	nachrs	nachrs	NOUN
gsrj-10	33	23	in	in	ADP
gsrj-10	33	24	the	the	DET
gsrj-10	33	25	brain	brain	NOUN
gsrj-10	33	26	.	.	PUNCT
gsrj-10	34	1	𝛼𝛼7/	𝛼𝛼7/	ADJ
gsrj-10	34	2	2	2	NUM
gsrj-10	34	3	double	double	ADJ
gsrj-10	34	4	knockout	knockout	NOUN
gsrj-10	34	5	mice	mouse	NOUN
gsrj-10	34	6	who	who	PRON
gsrj-10	34	7	experienced	experience	VERB
gsrj-10	34	8	the	the	DET
gsrj-10	34	9	social	social	ADJ
gsrj-10	34	10	defeat	defeat	NOUN
gsrj-10	34	11	(	(	PUNCT
gsrj-10	34	12	sd	sd	NOUN
gsrj-10	34	13	)	)	PUNCT
gsrj-10	34	14	paradigm	paradigm	NOUN
gsrj-10	34	15	did	do	AUX
gsrj-10	34	16	not	not	PART
gsrj-10	34	17	show	show	VERB
gsrj-10	34	18	the	the	DET
gsrj-10	34	19	same	same	ADJ
gsrj-10	34	20	increased	increase	VERB
gsrj-10	34	21	vta	vta	PROPN
gsrj-10	34	22	da	da	PROPN
gsrj-10	34	23	neuron	neuron	PROPN
gsrj-10	34	24	firing	fire	VERB
gsrj-10	34	25	as	as	ADP
gsrj-10	34	26	wild	wild	ADJ
gsrj-10	34	27	type	type	NOUN
gsrj-10	34	28	mice	mouse	NOUN
gsrj-10	34	29	who	who	PRON
gsrj-10	34	30	experienced	experience	VERB
gsrj-10	34	31	sd	sd	NOUN
gsrj-10	34	32	.	.	PUNCT
gsrj-10	35	1	73	73	NUM
gsrj-10	35	2	georgetown	georgetown	PROPN
gsrj-10	35	3	scientific	scientific	PROPN
gsrj-10	35	4	research	research	PROPN
gsrj-10	35	5	journal	journal	NOUN
gsrj-10	35	6	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	ADJ
gsrj-10	35	7	figure	figure	NOUN
gsrj-10	35	8	2	2	NUM
gsrj-10	35	9	.	.	PUNCT
gsrj-10	35	10	knockout	knockout	NOUN
gsrj-10	35	11	of	of	ADP
gsrj-10	35	12	nachrs	nachrs	ADJ
gsrj-10	35	13	eliminates	eliminate	VERB
gsrj-10	35	14	the	the	DET
gsrj-10	35	15	effects	effect	NOUN
gsrj-10	35	16	of	of	ADP
gsrj-10	35	17	social	social	ADJ
gsrj-10	35	18	stress	stress	NOUN
gsrj-10	35	19	on	on	ADP
gsrj-10	35	20	vta	vta	PROPN
gsrj-10	35	21	da	da	PROPN
gsrj-10	35	22	neurons	neuron	NOUN
gsrj-10	35	23	and	and	CCONJ
gsrj-10	35	24	social	social	ADJ
gsrj-10	35	25	behavior	behavior	NOUN
gsrj-10	35	26	.	.	PUNCT
gsrj-10	36	1	the	the	DET
gsrj-10	36	2	7/	7/	NUM
gsrj-10	36	3	�	�	SYM
gsrj-10	36	4	2	2	NUM
gsrj-10	36	5	knockout	knockout	NOUN
gsrj-10	36	6	is	be	AUX
gsrj-10	36	7	a	a	DET
gsrj-10	36	8	�	�	NOUN
gsrj-10	36	9	knockout	knockout	NOUN
gsrj-10	36	10	for	for	ADP
gsrj-10	36	11	both	both	PRON
gsrj-10	36	12	of	of	ADP
gsrj-10	36	13	the	the	DET
gsrj-10	36	14	primary	primary	ADJ
gsrj-10	36	15	nachr	nachr	PROPN
gsrj-10	36	16	subtypes	subtype	NOUN
gsrj-10	36	17	in	in	ADP
gsrj-10	36	18	the	the	DET
gsrj-10	36	19	brain	brain	NOUN
gsrj-10	36	20	.	.	PUNCT
gsrj-10	37	1	for	for	ADP
gsrj-10	37	2	graph	graph	NOUN
gsrj-10	37	3	a	a	DET
gsrj-10	37	4	,	,	PUNCT
gsrj-10	37	5	less	less	ADJ
gsrj-10	37	6	time	time	NOUN
gsrj-10	37	7	spent	spend	VERB
gsrj-10	37	8	in	in	ADP
gsrj-10	37	9	the	the	DET
gsrj-10	37	10	interacting	interact	VERB
gsrj-10	37	11	zone	zone	NOUN
gsrj-10	37	12	is	be	AUX
gsrj-10	37	13	taken	take	VERB
gsrj-10	37	14	to	to	PART
gsrj-10	37	15	mean	mean	VERB
gsrj-10	37	16	higher	high	ADJ
gsrj-10	37	17	effects	effect	NOUN
gsrj-10	37	18	of	of	ADP
gsrj-10	37	19	social	social	ADJ
gsrj-10	37	20	stress	stress	NOUN
gsrj-10	37	21	on	on	ADP
gsrj-10	37	22	the	the	DET
gsrj-10	37	23	mouse	mouse	NOUN
gsrj-10	37	24	.	.	PUNCT
gsrj-10	38	1	the	the	DET
gsrj-10	38	2	frequency	frequency	NOUN
gsrj-10	38	3	and	and	CCONJ
gsrj-10	38	4	burst	burst	ADJ
gsrj-10	38	5	activity	activity	NOUN
gsrj-10	38	6	�	�	NOUN
gsrj-10	38	7	measurements	measurement	NOUN
gsrj-10	38	8	seen	see	VERB
gsrj-10	38	9	in	in	ADP
gsrj-10	38	10	graphs	graph	NOUN
gsrj-10	38	11	b	b	NOUN
gsrj-10	38	12	and	and	CCONJ
gsrj-10	38	13	c	c	PROPN
gsrj-10	38	14	are	be	AUX
gsrj-10	38	15	measurements	measurement	NOUN
gsrj-10	38	16	from	from	ADP
gsrj-10	38	17	vta	vta	PROPN
gsrj-10	38	18	da	da	PROPN
gsrj-10	38	19	neurons	neuron	NOUN
gsrj-10	38	20	.	.	PUNCT
gsrj-10	39	1	graph	graph	NOUN
gsrj-10	39	2	b	b	PROPN
gsrj-10	39	3	shows	show	VERB
gsrj-10	39	4	vta	vta	PROPN
gsrj-10	39	5	da	da	PROPN
gsrj-10	39	6	neuron	neuron	PROPN
gsrj-10	39	7	frequency	frequency	NOUN
gsrj-10	39	8	and	and	CCONJ
gsrj-10	39	9	bursting	bursting	NOUN
gsrj-10	39	10	activity	activity	NOUN
gsrj-10	39	11	in	in	ADP
gsrj-10	39	12	mice	mouse	NOUN
gsrj-10	39	13	without	without	ADP
gsrj-10	39	14	the	the	DET
gsrj-10	39	15	nachr	nachr	PROPN
gsrj-10	39	16	knockout	knockout	NOUN
gsrj-10	39	17	,	,	PUNCT
gsrj-10	39	18	while	while	SCONJ
gsrj-10	39	19	graph	graph	NOUN
gsrj-10	39	20	c	c	PROPN
gsrj-10	39	21	shows	show	VERB
gsrj-10	39	22	vta	vta	PROPN
gsrj-10	39	23	da	da	PROPN
gsrj-10	39	24	neuronal	neuronal	ADJ
gsrj-10	39	25	activity	activity	NOUN
gsrj-10	39	26	gps	gps	PROPN
gsrj-10	39	27	�	�	PROPN
gsrj-10	39	28	njdf	njdf	NOUN
gsrj-10	39	29	�	�	PROPN
gsrj-10	39	30	xjui	xjui	PROPN
gsrj-10	39	31	�	�	PROPN
gsrj-10	39	32	uif	uif	PROPN
gsrj-10	39	33	�	�	PROPN
gsrj-10	39	34	lopdlpvu	lopdlpvu	PROPN
gsrj-10	39	35	�	�	PROPN
gsrj-10	39	36	�	�	PROPN
gsrj-10	39	37	'	'	PUNCT
gsrj-10	39	38	jhvsft	jhvsft	PROPN
gsrj-10	39	39	�	�	PROPN
gsrj-10	39	40	ublfo	ublfo	PROPN
gsrj-10	39	41	�	�	PROPN
gsrj-10	39	42	gspn	gspn	PROPN
gsrj-10	39	43	�	�	PROPN
gsrj-10	39	44	.psfm	.psfm	PROPN
gsrj-10	39	45	�	�	PROPN
gsrj-10	39	46	fu	fu	PROPN
gsrj-10	39	47	�	�	PROPN
gsrj-10	39	48	bm	bm	PROPN
gsrj-10	39	49	�	�	PROPN
gsrj-10	39	50	�	�	PROPN
gsrj-10	39	51	�	�	PROPN
gsrj-10	39	52	�	�	PROPN
gsrj-10	39	53	�	�	PROPN
gsrj-10	39	54	�	�	PROPN
gsrj-10	39	55	�	�	PROPN
gsrj-10	39	56	�	�	PROPN
gsrj-10	39	57	�	�	PROPN
gsrj-10	39	58	�	�	PROPN
gsrj-10	39	59	additionally	additionally	ADV
gsrj-10	39	60	,	,	PUNCT
gsrj-10	39	61	knockout	knockout	NOUN
gsrj-10	39	62	mice	mouse	NOUN
gsrj-10	39	63	did	do	AUX
gsrj-10	39	64	not	not	PART
gsrj-10	39	65	exhibit	exhibit	VERB
gsrj-10	39	66	social	social	ADJ
gsrj-10	39	67	aversion	aversion	NOUN
gsrj-10	39	68	,	,	PUNCT
gsrj-10	39	69	contrasting	contrast	VERB
gsrj-10	39	70	the	the	DET
gsrj-10	39	71	typical	typical	ADJ
gsrj-10	39	72	results	result	NOUN
gsrj-10	39	73	of	of	ADP
gsrj-10	39	74	sd	sd	NOUN
gsrj-10	39	75	on	on	ADP
gsrj-10	39	76	wild	wild	ADJ
gsrj-10	39	77	type	type	NOUN
gsrj-10	39	78	mice	mouse	NOUN
gsrj-10	39	79	(	(	PUNCT
gsrj-10	39	80	figure	figure	NOUN
gsrj-10	39	81	2	2	NUM
gsrj-10	39	82	)	)	PUNCT
gsrj-10	39	83	.	.	PUNCT
gsrj-10	40	1	corroborating	corroborate	VERB
gsrj-10	40	2	this	this	DET
gsrj-10	40	3	information	information	NOUN
gsrj-10	40	4	suggests	suggest	VERB
gsrj-10	40	5	that	that	SCONJ
gsrj-10	40	6	nachrs	nachrs	ADV
gsrj-10	40	7	in	in	ADP
gsrj-10	40	8	the	the	DET
gsrj-10	40	9	brain	brain	NOUN
gsrj-10	40	10	are	be	AUX
gsrj-10	40	11	key	key	ADJ
gsrj-10	40	12	to	to	ADP
gsrj-10	40	13	both	both	CCONJ
gsrj-10	40	14	the	the	DET
gsrj-10	40	15	cellular	cellular	ADJ
gsrj-10	40	16	and	and	CCONJ
gsrj-10	40	17	the	the	DET
gsrj-10	40	18	behavioral	behavioral	ADJ
gsrj-10	40	19	effects	effect	NOUN
gsrj-10	40	20	of	of	ADP
gsrj-10	40	21	stress	stress	NOUN
gsrj-10	40	22	.	.	PUNCT
gsrj-10	41	1	unsurprisingly	unsurprisingly	ADV
gsrj-10	41	2	,	,	PUNCT
gsrj-10	41	3	nicotine	nicotine	ADJ
gsrj-10	41	4	injection	injection	NOUN
gsrj-10	41	5	also	also	ADV
gsrj-10	41	6	failed	fail	VERB
gsrj-10	41	7	to	to	PART
gsrj-10	41	8	induce	induce	VERB
gsrj-10	41	9	increased	increase	VERB
gsrj-10	41	10	vta	vta	PROPN
gsrj-10	41	11	da	da	PROPN
gsrj-10	41	12	neuron	neuron	PROPN
gsrj-10	41	13	firing	fire	VERB
gsrj-10	41	14	in	in	ADP
gsrj-10	41	15	knockout	knockout	NOUN
gsrj-10	41	16	mice	mouse	NOUN
gsrj-10	41	17	,	,	PUNCT
gsrj-10	41	18	confirming	confirm	VERB
gsrj-10	41	19	that	that	SCONJ
gsrj-10	41	20	stress	stress	NOUN
gsrj-10	41	21	and	and	CCONJ
gsrj-10	41	22	nicotine	nicotine	VERB
gsrj-10	41	23	interact	interact	VERB
gsrj-10	41	24	with	with	ADP
gsrj-10	41	25	the	the	DET
gsrj-10	41	26	same	same	ADJ
gsrj-10	41	27	nachrs	nachrs	NOUN
gsrj-10	41	28	.	.	PUNCT
gsrj-10	42	1	furthermore	furthermore	ADV
gsrj-10	42	2	,	,	PUNCT
gsrj-10	42	3	mice	mouse	NOUN
gsrj-10	42	4	given	give	VERB
gsrj-10	42	5	acute	acute	NOUN
gsrj-10	42	6	nicotine	nicotine	NOUN
gsrj-10	42	7	along	along	ADP
gsrj-10	42	8	with	with	ADP
gsrj-10	42	9	subthreshold	subthreshold	ADJ
gsrj-10	42	10	sd	sd	PROPN
gsrj-10	42	11	(	(	PUNCT
gsrj-10	42	12	subsd	subsd	NOUN
gsrj-10	42	13	)	)	PUNCT
gsrj-10	42	14	exhibited	exhibit	VERB
gsrj-10	42	15	much	much	ADV
gsrj-10	42	16	higher	high	ADJ
gsrj-10	42	17	vta	vta	PROPN
gsrj-10	42	18	da	da	PROPN
gsrj-10	42	19	neuron	neuron	PROPN
gsrj-10	42	20	excitability	excitability	NOUN
gsrj-10	42	21	compared	compare	VERB
gsrj-10	42	22	to	to	PART
gsrj-10	42	23	control	control	VERB
gsrj-10	42	24	mice	mouse	NOUN
gsrj-10	42	25	who	who	PRON
gsrj-10	42	26	experienced	experience	VERB
gsrj-10	42	27	subsd	subsd	NOUN
gsrj-10	42	28	with	with	ADP
gsrj-10	42	29	no	no	DET
gsrj-10	42	30	nicotine	nicotine	NOUN
gsrj-10	42	31	administration	administration	NOUN
gsrj-10	42	32	.	.	PUNCT
gsrj-10	43	1	this	this	PRON
gsrj-10	43	2	demonstrated	demonstrate	VERB
gsrj-10	43	3	a	a	DET
gsrj-10	43	4	clear	clear	ADJ
gsrj-10	43	5	remodeling	remodeling	NOUN
gsrj-10	43	6	of	of	ADP
gsrj-10	43	7	nicotinic	nicotinic	ADJ
gsrj-10	43	8	synapses	synapsis	NOUN
gsrj-10	43	9	on	on	ADP
gsrj-10	43	10	the	the	DET
gsrj-10	43	11	vta	vta	PROPN
gsrj-10	43	12	.	.	PUNCT
gsrj-10	44	1	mice	mouse	NOUN
gsrj-10	44	2	who	who	PRON
gsrj-10	44	3	underwent	undergo	VERB
gsrj-10	44	4	sd	sd	NOUN
gsrj-10	44	5	also	also	ADV
gsrj-10	44	6	had	have	VERB
gsrj-10	44	7	a	a	DET
gsrj-10	44	8	greater	great	ADJ
gsrj-10	44	9	number	number	NOUN
gsrj-10	44	10	of	of	ADP
gsrj-10	44	11	cholinergic	cholinergic	ADJ
gsrj-10	44	12	transporters	transporter	NOUN
gsrj-10	44	13	and	and	CCONJ
gsrj-10	44	14	nachrbinding	nachrbinde	VERB
gsrj-10	44	15	sites	site	NOUN
gsrj-10	44	16	,	,	PUNCT
gsrj-10	44	17	indicating	indicate	VERB
gsrj-10	44	18	a	a	DET
gsrj-10	44	19	comprehensive	comprehensive	ADJ
gsrj-10	44	20	effect	effect	NOUN
gsrj-10	44	21	of	of	ADP
gsrj-10	44	22	stress	stress	NOUN
gsrj-10	44	23	on	on	ADP
gsrj-10	44	24	nicotinic	nicotinic	ADJ
gsrj-10	44	25	pathways	pathway	NOUN
gsrj-10	44	26	in	in	ADP
gsrj-10	44	27	the	the	DET
gsrj-10	44	28	vta	vta	PROPN
gsrj-10	44	29	.	.	PUNCT
gsrj-10	45	1	morel	morel	PROPN
gsrj-10	45	2	et	et	PROPN
gsrj-10	45	3	al	al	PROPN
gsrj-10	45	4	.	.	PROPN
gsrj-10	45	5	,	,	PUNCT
gsrj-10	45	6	2018	2018	NUM
gsrj-10	45	7	employed	employ	VERB
gsrj-10	45	8	pnu	pnu	NOUN
gsrj-10	45	9	,	,	PUNCT
gsrj-10	45	10	an	an	DET
gsrj-10	45	11	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	45	12	�	�	PROPN
gsrj-10	45	13	nachr	nachr	PROPN
gsrj-10	45	14	positive	positive	ADJ
gsrj-10	45	15	allosteric	allosteric	ADJ
gsrj-10	45	16	modulator	modulator	NOUN
gsrj-10	45	17	,	,	PUNCT
gsrj-10	45	18	to	to	PART
gsrj-10	45	19	explore	explore	VERB
gsrj-10	45	20	subtype	subtype	NOUN
gsrj-10	45	21	-	-	PUNCT
gsrj-10	45	22	specific	specific	ADJ
gsrj-10	45	23	effects	effect	NOUN
gsrj-10	45	24	.	.	PUNCT
gsrj-10	46	1	pnu	pnu	NOUN
gsrj-10	46	2	-	-	PUNCT
gsrj-10	46	3	treated	treat	VERB
gsrj-10	46	4	mice	mouse	NOUN
gsrj-10	46	5	who	who	PRON
gsrj-10	46	6	experienced	experience	VERB
gsrj-10	46	7	subsd	subsd	NOUN
gsrj-10	46	8	exhibited	exhibit	VERB
gsrj-10	46	9	da	da	PROPN
gsrj-10	46	10	vta	vta	PROPN
gsrj-10	46	11	firing	firing	NOUN
gsrj-10	46	12	increases	increase	NOUN
gsrj-10	46	13	equivalent	equivalent	ADJ
gsrj-10	46	14	to	to	ADP
gsrj-10	46	15	that	that	PRON
gsrj-10	46	16	found	find	VERB
gsrj-10	46	17	in	in	ADP
gsrj-10	46	18	mice	mouse	NOUN
gsrj-10	46	19	experiencing	experience	VERB
gsrj-10	46	20	the	the	DET
gsrj-10	46	21	full	full	ADJ
gsrj-10	46	22	sd	sd	NOUN
gsrj-10	46	23	paradigm	paradigm	NOUN
gsrj-10	46	24	.	.	PUNCT
gsrj-10	47	1	additionally	additionally	ADV
gsrj-10	47	2	,	,	PUNCT
gsrj-10	47	3	these	these	DET
gsrj-10	47	4	mice	mouse	NOUN
gsrj-10	47	5	exhibited	exhibit	VERB
gsrj-10	47	6	social	social	ADJ
gsrj-10	47	7	aversion	aversion	NOUN
gsrj-10	47	8	quite	quite	ADV
gsrj-10	47	9	similar	similar	ADJ
gsrj-10	47	10	to	to	ADP
gsrj-10	47	11	those	those	PRON
gsrj-10	47	12	undergoing	undergo	VERB
gsrj-10	47	13	the	the	DET
gsrj-10	47	14	full	full	ADJ
gsrj-10	47	15	sd	sd	NOUN
gsrj-10	47	16	paradigm	paradigm	NOUN
gsrj-10	47	17	.	.	PUNCT
gsrj-10	48	1	mice	mouse	NOUN
gsrj-10	48	2	who	who	PRON
gsrj-10	48	3	underwent	undergo	VERB
gsrj-10	48	4	subsd	subsd	NOUN
gsrj-10	48	5	and	and	CCONJ
gsrj-10	48	6	were	be	AUX
gsrj-10	48	7	pre	pre	VERB
gsrj-10	48	8	-	-	VERB
gsrj-10	48	9	treated	treat	VERB
gsrj-10	48	10	with	with	ADP
gsrj-10	48	11	ns9238	ns9238	PROPN
gsrj-10	48	12	,	,	PUNCT
gsrj-10	48	13	a	a	DET
gsrj-10	48	14	2	2	NUM
gsrj-10	48	15	nachr	nachr	NOUN
gsrj-10	48	16	positive	positive	ADJ
gsrj-10	48	17	allosteric	allosteric	ADJ
gsrj-10	48	18	�	�	NOUN
gsrj-10	48	19	modulator	modulator	NOUN
gsrj-10	48	20	,	,	PUNCT
gsrj-10	48	21	exhibited	exhibit	VERB
gsrj-10	48	22	da	da	PROPN
gsrj-10	48	23	vta	vta	PROPN
gsrj-10	48	24	firing	firing	NOUN
gsrj-10	48	25	and	and	CCONJ
gsrj-10	48	26	behavioral	behavioral	ADJ
gsrj-10	48	27	changes	change	NOUN
gsrj-10	48	28	similar	similar	ADJ
gsrj-10	48	29	to	to	ADP
gsrj-10	48	30	wt	wt	NOUN
gsrj-10	48	31	mice	mouse	NOUN
gsrj-10	48	32	who	who	PRON
gsrj-10	48	33	underwent	undergo	VERB
gsrj-10	48	34	subsd	subsd	NOUN
gsrj-10	48	35	.	.	PUNCT
gsrj-10	49	1	thus	thus	ADV
gsrj-10	49	2	,	,	PUNCT
gsrj-10	49	3	it	it	PRON
gsrj-10	49	4	seems	seem	VERB
gsrj-10	49	5	that	that	SCONJ
gsrj-10	49	6	activation	activation	NOUN
gsrj-10	49	7	of	of	ADP
gsrj-10	49	8	the	the	DET
gsrj-10	49	9	heteromeric	heteromeric	ADJ
gsrj-10	49	10	2	2	PROPN
gsrj-10	49	11	nachr	nachr	NOUN
gsrj-10	49	12	does	do	AUX
gsrj-10	49	13	not	not	PART
gsrj-10	49	14	�	�	PROPN
gsrj-10	49	15	significantly	significantly	ADV
gsrj-10	49	16	modulate	modulate	VERB
gsrj-10	49	17	the	the	DET
gsrj-10	49	18	effects	effect	NOUN
gsrj-10	49	19	of	of	ADP
gsrj-10	49	20	stress	stress	NOUN
gsrj-10	49	21	.	.	PUNCT
gsrj-10	50	1	both	both	DET
gsrj-10	50	2	pnu	pnu	NOUN
gsrj-10	50	3	and	and	CCONJ
gsrj-10	50	4	nicotine	nicotine	NOUN
gsrj-10	50	5	administered	administer	VERB
gsrj-10	50	6	via	via	ADP
gsrj-10	50	7	a	a	DET
gsrj-10	50	8	cannula	cannula	NOUN
gsrj-10	50	9	led	lead	VERB
gsrj-10	50	10	to	to	ADP
gsrj-10	50	11	increased	increase	VERB
gsrj-10	50	12	social	social	ADJ
gsrj-10	50	13	aversion	aversion	NOUN
gsrj-10	50	14	when	when	SCONJ
gsrj-10	50	15	paired	pair	VERB
gsrj-10	50	16	with	with	ADP
gsrj-10	50	17	subsd	subsd	NOUN
gsrj-10	50	18	,	,	PUNCT
gsrj-10	50	19	confirming	confirm	VERB
gsrj-10	50	20	that	that	SCONJ
gsrj-10	50	21	this	this	DET
gsrj-10	50	22	stress	stress	NOUN
gsrj-10	50	23	-	-	PUNCT
gsrj-10	50	24	nicotinic	nicotinic	ADJ
gsrj-10	50	25	relationship	relationship	NOUN
gsrj-10	50	26	was	be	AUX
gsrj-10	50	27	occurring	occur	VERB
gsrj-10	50	28	specifically	specifically	ADV
gsrj-10	50	29	in	in	ADP
gsrj-10	50	30	the	the	DET
gsrj-10	50	31	vta	vta	PROPN
gsrj-10	50	32	.	.	PUNCT
gsrj-10	51	1	74	74	NUM
gsrj-10	51	2	georgetown	georgetown	PROPN
gsrj-10	51	3	scientific	scientific	PROPN
gsrj-10	51	4	research	research	NOUN
gsrj-10	51	5	journal	journal	PROPN
gsrj-10	51	6	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	VERB
gsrj-10	51	7	these	these	DET
gsrj-10	51	8	results	result	NOUN
gsrj-10	51	9	implicate	implicate	VERB
gsrj-10	51	10	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	51	11	nachrs	nachrs	ADJ
gsrj-10	51	12	as	as	ADP
gsrj-10	51	13	the	the	DET
gsrj-10	51	14	primary	primary	ADJ
gsrj-10	51	15	receptor	receptor	NOUN
gsrj-10	51	16	upon	upon	SCONJ
gsrj-10	51	17	which	which	PRON
gsrj-10	51	18	stress	stress	NOUN
gsrj-10	51	19	has	have	VERB
gsrj-10	51	20	its	its	PRON
gsrj-10	51	21	synaptic	synaptic	ADJ
gsrj-10	51	22	effects	effect	NOUN
gsrj-10	51	23	in	in	ADP
gsrj-10	51	24	the	the	DET
gsrj-10	51	25	cholinergic	cholinergic	ADJ
gsrj-10	51	26	vta	vta	PROPN
gsrj-10	51	27	system	system	NOUN
gsrj-10	51	28	.	.	PUNCT
gsrj-10	52	1	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	52	2	nachrs	nachrs	ADV
gsrj-10	52	3	can	can	AUX
gsrj-10	52	4	therefore	therefore	ADV
gsrj-10	52	5	be	be	AUX
gsrj-10	52	6	considered	consider	VERB
gsrj-10	52	7	as	as	ADP
gsrj-10	52	8	possible	possible	ADJ
gsrj-10	52	9	therapeutic	therapeutic	ADJ
gsrj-10	52	10	targets	target	NOUN
gsrj-10	52	11	for	for	ADP
gsrj-10	52	12	stress	stress	NOUN
gsrj-10	52	13	and	and	CCONJ
gsrj-10	52	14	mood	mood	NOUN
gsrj-10	52	15	disorders	disorder	NOUN
gsrj-10	52	16	going	go	VERB
gsrj-10	52	17	forward	forward	ADV
gsrj-10	52	18	.	.	PUNCT
gsrj-10	53	1	interestingly	interestingly	ADV
gsrj-10	53	2	,	,	PUNCT
gsrj-10	53	3	stress	stress	NOUN
gsrj-10	53	4	and	and	CCONJ
gsrj-10	53	5	nicotine	nicotine	VERB
gsrj-10	53	6	both	both	PRON
gsrj-10	53	7	seem	seem	VERB
gsrj-10	53	8	to	to	PART
gsrj-10	53	9	have	have	VERB
gsrj-10	53	10	a	a	DET
gsrj-10	53	11	significant	significant	ADJ
gsrj-10	53	12	effect	effect	NOUN
gsrj-10	53	13	on	on	ADP
gsrj-10	53	14	long	long	ADJ
gsrj-10	53	15	-	-	PUNCT
gsrj-10	53	16	term	term	NOUN
gsrj-10	53	17	potentiation	potentiation	NOUN
gsrj-10	53	18	(	(	PUNCT
gsrj-10	53	19	ltp	ltp	NOUN
gsrj-10	53	20	)	)	PUNCT
gsrj-10	53	21	of	of	ADP
gsrj-10	53	22	synapses	synapsis	NOUN
gsrj-10	53	23	on	on	ADP
gsrj-10	53	24	da	da	PROPN
gsrj-10	53	25	vta	vta	PROPN
gsrj-10	53	26	neurons	neuron	NOUN
gsrj-10	53	27	.	.	PUNCT
gsrj-10	54	1	mice	mouse	NOUN
gsrj-10	54	2	who	who	PRON
gsrj-10	54	3	underwent	undergo	VERB
gsrj-10	54	4	sd	sd	NOUN
gsrj-10	54	5	were	be	AUX
gsrj-10	54	6	found	find	VERB
gsrj-10	54	7	to	to	PART
gsrj-10	54	8	have	have	VERB
gsrj-10	54	9	an	an	DET
gsrj-10	54	10	increased	increase	VERB
gsrj-10	54	11	ampar	ampar	NOUN
gsrj-10	54	12	/	/	SYM
gsrj-10	54	13	nmdar	nmdar	PROPN
gsrj-10	54	14	ratio	ratio	NOUN
gsrj-10	54	15	for	for	ADP
gsrj-10	54	16	their	their	PRON
gsrj-10	54	17	da	da	PROPN
gsrj-10	54	18	vta	vta	PROPN
gsrj-10	54	19	neurons	neuron	NOUN
gsrj-10	54	20	,	,	PUNCT
gsrj-10	54	21	signifying	signify	VERB
gsrj-10	54	22	ltp	ltp	PROPN
gsrj-10	54	23	occurring	occur	VERB
gsrj-10	54	24	at	at	ADP
gsrj-10	54	25	these	these	DET
gsrj-10	54	26	synapses	synapsis	NOUN
gsrj-10	54	27	.	.	PUNCT
gsrj-10	55	1	ampar	ampar	PROPN
gsrj-10	55	2	/	/	SYM
gsrj-10	55	3	nmdar	nmdar	PROPN
gsrj-10	55	4	ratio	ratio	NOUN
gsrj-10	55	5	serves	serve	VERB
gsrj-10	55	6	as	as	ADP
gsrj-10	55	7	a	a	DET
gsrj-10	55	8	marker	marker	NOUN
gsrj-10	55	9	of	of	ADP
gsrj-10	55	10	ltp	ltp	PROPN
gsrj-10	55	11	,	,	PUNCT
gsrj-10	55	12	as	as	SCONJ
gsrj-10	55	13	the	the	DET
gsrj-10	55	14	insertion	insertion	NOUN
gsrj-10	55	15	of	of	ADP
gsrj-10	55	16	ampars	ampar	NOUN
gsrj-10	55	17	,	,	PUNCT
gsrj-10	55	18	and	and	CCONJ
gsrj-10	55	19	thus	thus	ADV
gsrj-10	55	20	an	an	DET
gsrj-10	55	21	increase	increase	NOUN
gsrj-10	55	22	in	in	ADP
gsrj-10	55	23	ampar	ampar	NOUN
gsrj-10	55	24	/	/	SYM
gsrj-10	55	25	nmdar	nmdar	PROPN
gsrj-10	55	26	ratio	ratio	NOUN
gsrj-10	55	27	,	,	PUNCT
gsrj-10	55	28	is	be	AUX
gsrj-10	55	29	the	the	DET
gsrj-10	55	30	primary	primary	ADJ
gsrj-10	55	31	biomarker	biomarker	NOUN
gsrj-10	55	32	of	of	ADP
gsrj-10	55	33	ltp	ltp	PROPN
gsrj-10	55	34	.	.	PUNCT
gsrj-10	56	1	ltp	ltp	PROPN
gsrj-10	56	2	at	at	ADP
gsrj-10	56	3	these	these	DET
gsrj-10	56	4	synapses	synapsis	NOUN
gsrj-10	56	5	helps	help	VERB
gsrj-10	56	6	to	to	PART
gsrj-10	56	7	complete	complete	VERB
gsrj-10	56	8	the	the	DET
gsrj-10	56	9	picture	picture	NOUN
gsrj-10	56	10	of	of	ADP
gsrj-10	56	11	the	the	DET
gsrj-10	56	12	cholinergic	cholinergic	ADJ
gsrj-10	56	13	-	-	PUNCT
gsrj-10	56	14	stress	stress	NOUN
gsrj-10	56	15	-	-	PUNCT
gsrj-10	56	16	vta	vta	NOUN
gsrj-10	56	17	pathway	pathway	NOUN
gsrj-10	56	18	as	as	SCONJ
gsrj-10	56	19	it	it	PRON
gsrj-10	56	20	likely	likely	ADV
gsrj-10	56	21	contributes	contribute	VERB
gsrj-10	56	22	to	to	ADP
gsrj-10	56	23	greater	great	ADJ
gsrj-10	56	24	firing	firing	NOUN
gsrj-10	56	25	rates	rate	NOUN
gsrj-10	56	26	and	and	CCONJ
gsrj-10	56	27	bursting	bursting	NOUN
gsrj-10	56	28	activity	activity	NOUN
gsrj-10	56	29	in	in	ADP
gsrj-10	56	30	da	da	PROPN
gsrj-10	56	31	vta	vta	PROPN
gsrj-10	56	32	neurons	neuron	NOUN
gsrj-10	56	33	for	for	ADP
gsrj-10	56	34	mice	mouse	NOUN
gsrj-10	56	35	under	under	ADP
gsrj-10	56	36	stress	stress	NOUN
gsrj-10	56	37	.	.	PUNCT
gsrj-10	57	1	mice	mouse	NOUN
gsrj-10	57	2	treated	treat	VERB
gsrj-10	57	3	with	with	ADP
gsrj-10	57	4	pnu	pnu	NOUN
gsrj-10	57	5	also	also	ADV
gsrj-10	57	6	experienced	experience	VERB
gsrj-10	57	7	increased	increase	VERB
gsrj-10	57	8	ltp	ltp	NOUN
gsrj-10	57	9	on	on	ADP
gsrj-10	57	10	da	da	PROPN
gsrj-10	57	11	vta	vta	PROPN
gsrj-10	57	12	neurons	neuron	NOUN
gsrj-10	57	13	(	(	PUNCT
gsrj-10	57	14	figure	figure	NOUN
gsrj-10	57	15	3	3	NUM
gsrj-10	57	16	)	)	PUNCT
gsrj-10	57	17	.	.	PUNCT
gsrj-10	58	1	�	�	NOUN
gsrj-10	58	2	#	#	NOUN
gsrj-10	58	3	!	!	PUNCT
gsrj-10	59	1	/,	/,	PROPN
gsrj-10	59	2	�	�	PROPN
gsrj-10	59	3	5i85	5i85	NUM
gsrj-10	59	4	�	�	PROPN
gsrj-10	59	5	�	�	PROPN
gsrj-10	59	6	'#(#-.,	'#(#-.,	PROPN
gsrj-10	59	7	�	�	PROPN
gsrj-10	59	8	.#)(5	.#)(5	PROPN
gsrj-10	59	9	)	)	PUNCT
gsrj-10	59	10	5	5	NUM
gsrj-10	59	11	�	�	PROPN
gsrj-10	59	12	�	�	PROPN
gsrj-10	59	13	�	�	PROPN
gsrj-10	59	14	65	65	NUM
gsrj-10	59	15	�	�	PROPN
gsrj-10	59	16	(5𝛼𝛼𝛼𝛼m5(	(5𝛼𝛼𝛼𝛼m5(	SYM
gsrj-10	59	17	�	�	PROPN
gsrj-10	59	18	�	�	PROPN
gsrj-10	59	19	"	"	PUNCT
gsrj-10	59	20	�	�	PROPN
gsrj-10	59	21	5	5	NUM
gsrj-10	59	22	*	*	SYM
gsrj-10	59	23	)	)	PUNCT
gsrj-10	59	24	-#.#0	-#.#0	X
gsrj-10	59	25	�	�	PROPN
gsrj-10	59	26	5	5	NUM
gsrj-10	59	27	�	�	PROPN
gsrj-10	59	28	&	&	CCONJ
gsrj-10	59	29	&	&	CCONJ
gsrj-10	59	30	)	)	PUNCT
gsrj-10	59	31	-.	-.	PROPN
gsrj-10	59	32	�	�	PROPN
gsrj-10	59	33	,#	,#	PUNCT
gsrj-10	59	34	�	�	PROPN
gsrj-10	59	35	5	5	NUM
gsrj-10	59	36	'	'	NUM
gsrj-10	59	37	)	)	PUNCT
gsrj-10	59	38	�	�	PROPN
gsrj-10	59	39	/&	/&	SYM
gsrj-10	59	40	�	�	PROPN
gsrj-10	59	41	.),65	.),65	PROPN
gsrj-10	59	42	.)5	.)5	PROPN
gsrj-10	59	43	'	'	PUNCT
gsrj-10	59	44	#	#	SYM
gsrj-10	59	45	�	�	NOUN
gsrj-10	59	46	�	�	NOUN
gsrj-10	59	47	5	5	NUM
gsrj-10	59	48	#	#	SYM
gsrj-10	59	49	(	(	PUNCT
gsrj-10	59	50	�	�	PROPN
gsrj-10	59	51	,	,	PUNCT
gsrj-10	59	52	�	�	PROPN
gsrj-10	59	53	�	�	PROPN
gsrj-10	59	54	-	-	PUNCT
gsrj-10	59	55	�	�	PROPN
gsrj-10	59	56	-55	-55	SYM
gsrj-10	59	57	�	�	PROPN
gsrj-10	59	58	�	�	PROPN
gsrj-10	59	59	�	�	NOUN
gsrj-10	59	60	5	5	NUM
gsrj-10	59	61	#	#	NOUN
gsrj-10	59	62	(	(	PUNCT
gsrj-10	59	63	5	5	NUM
gsrj-10	59	64	�	�	PROPN
gsrj-10	59	65	�	�	PROPN
gsrj-10	59	66	�	�	PROPN
gsrj-10	59	67	5	5	NUM
gsrj-10	59	68	�	�	PROPN
gsrj-10	59	69	�	�	PROPN
gsrj-10	59	70	5(	5(	NUM
gsrj-10	59	71	�	�	PROPN
gsrj-10	59	72	/,)(-5	/,)(-5	PUNCT
gsrj-10	59	73	)	)	PUNCT
gsrj-10	59	74	&	&	CCONJ
gsrj-10	59	75	&	&	CCONJ
gsrj-10	59	76	)	)	PUNCT
gsrj-10	59	77	1#(!5	1#(!5	NUM
gsrj-10	59	78	."	."	SYM
gsrj-10	59	79	�	�	PROPN
gsrj-10	59	80	5	5	NUM
gsrj-10	59	81	�	�	PROPN
gsrj-10	59	82	/	/	SYM
gsrj-10	59	83	�	�	PROPN
gsrj-10	59	84	�	�	NOUN
gsrj-10	59	85	�	�	PROPN
gsrj-10	59	86	55	55	NUM
gsrj-10	59	87	*	*	PUNCT
gsrj-10	59	88	�	�	PROPN
gsrj-10	59	89	,	,	PUNCT
gsrj-10	59	90	�	�	PROPN
gsrj-10	59	91	�	�	NOUN
gsrj-10	59	92	#	#	NOUN
gsrj-10	59	93	!	!	PUNCT
gsrj-10	59	94	'	'	NUM
gsrj-10	59	95	8	8	NUM
gsrj-10	59	96	�	�	PROPN
gsrj-10	59	97	*	*	PUNCT
gsrj-10	59	98	oufsftujohmz	oufsftujohmz	PROPN
gsrj-10	59	99	�	�	PROPN
gsrj-10	59	100	njdf	njdf	NOUN
gsrj-10	59	101	�	�	PROPN
gsrj-10	59	102	eje	eje	PROPN
gsrj-10	59	103	�	�	PROPN
gsrj-10	59	104	opu	opu	PROPN
gsrj-10	59	105	�	�	PROPN
gsrj-10	59	106	fyqfsjfodf	fyqfsjfodf	PROPN
gsrj-10	59	107	�	�	PROPN
gsrj-10	59	108	jodsfbtfe	jodsfbtfe	PROPN
gsrj-10	59	109	�	�	PROPN
gsrj-10	59	110	-51	-51	PROPN
gsrj-10	59	111	�	�	PROPN
gsrj-10	59	112	xifo	xifo	ADJ
gsrj-10	59	113	�	�	PROPN
gsrj-10	59	114	hjwfo	hjwfo	PROPN
gsrj-10	59	115	�	�	PROPN
gsrj-10	59	116	1/6	1/6	NUM
gsrj-10	59	117	�	�	PROPN
gsrj-10	59	118	jo	jo	PROPN
gsrj-10	59	119	�	�	PROPN
gsrj-10	59	120	uif	uif	PROPN
gsrj-10	59	121	�	�	PROPN
gsrj-10	59	122	bctfodf	bctfodf	PROPN
gsrj-10	59	123	�	�	PROPN
gsrj-10	59	124	pg	pg	NOUN
gsrj-10	59	125	�	�	PROPN
gsrj-10	59	126	4vc4%	4vc4%	NUM
gsrj-10	59	127	�	�	PROPN
gsrj-10	59	128	fyqptvsf	fyqptvsf	PROPN
gsrj-10	59	129	�	�	PROPN
gsrj-10	59	130	jnqmzjoh	jnqmzjoh	PROPN
gsrj-10	59	131	�	�	PROPN
gsrj-10	59	132	uif	uif	PROPN
gsrj-10	59	133	�	�	PROPN
gsrj-10	59	134	foibodfe	foibodfe	PROPN
gsrj-10	59	135	�	�	PROPN
gsrj-10	59	136	-51	-51	PROPN
gsrj-10	59	137	�	�	PROPN
gsrj-10	59	138	ifsf	ifsf	PROPN
gsrj-10	59	139	�	�	PROPN
gsrj-10	59	140	jt	jt	PROPN
gsrj-10	59	141	�	�	PROPN
gsrj-10	59	142	joeffe	joeffe	PROPN
gsrj-10	59	143	�	�	PROPN
gsrj-10	59	144	qsjnbsjmz	qsjnbsjmz	PROPN
gsrj-10	59	145	�	�	PROPN
gsrj-10	59	146	dbvtfe	dbvtfe	PROPN
gsrj-10	59	147	�	�	PROPN
gsrj-10	59	148	cz	cz	PROPN
gsrj-10	59	149	�	�	PROPN
gsrj-10	59	150	uif	uif	PROPN
gsrj-10	59	151	�	�	PROPN
gsrj-10	59	152	fggfdut	fggfdut	PROPN
gsrj-10	59	153	�	�	PROPN
gsrj-10	59	154	pg	pg	NOUN
gsrj-10	59	155	�	�	PROPN
gsrj-10	59	156	tusftt	tusftt	PROPN
gsrj-10	59	157	�	�	PROPN
gsrj-10	59	158	�	�	PROPN
gsrj-10	59	159	'	'	PUNCT
gsrj-10	59	160	jhvsft	jhvsft	PROPN
gsrj-10	59	161	�	�	PROPN
gsrj-10	59	162	ublfo	ublfo	PROPN
gsrj-10	59	163	�	�	PROPN
gsrj-10	59	164	gspn	gspn	PROPN
gsrj-10	59	165	�	�	PROPN
gsrj-10	59	166	.psfm	.psfm	PROPN
gsrj-10	59	167	�	�	PROPN
gsrj-10	59	168	fu	fu	PROPN
gsrj-10	59	169	�	�	PROPN
gsrj-10	59	170	bm	bm	PROPN
gsrj-10	59	171	�	�	PROPN
gsrj-10	59	172	�	�	PROPN
gsrj-10	59	173	�	�	PROPN
gsrj-10	59	174	�	�	PROPN
gsrj-10	59	175	�	�	PROPN
gsrj-10	59	176	�	�	PROPN
gsrj-10	59	177	�	�	PROPN
gsrj-10	59	178	�	�	PROPN
gsrj-10	59	179	�	�	PROPN
gsrj-10	59	180	changes	change	NOUN
gsrj-10	59	181	in	in	ADP
gsrj-10	59	182	ltp	ltp	PROPN
gsrj-10	59	183	may	may	AUX
gsrj-10	59	184	be	be	AUX
gsrj-10	59	185	the	the	DET
gsrj-10	59	186	main	main	ADJ
gsrj-10	59	187	way	way	NOUN
gsrj-10	59	188	in	in	ADP
gsrj-10	59	189	which	which	PRON
gsrj-10	59	190	stress	stress	NOUN
gsrj-10	59	191	and	and	CCONJ
gsrj-10	59	192	nicotine	nicotine	VERB
gsrj-10	59	193	remodel	remodel	PROPN
gsrj-10	59	194	vta	vta	PROPN
gsrj-10	59	195	da	da	PROPN
gsrj-10	59	196	synapses	synapsis	NOUN
gsrj-10	59	197	.	.	PUNCT
gsrj-10	60	1	they	they	PRON
gsrj-10	60	2	both	both	PRON
gsrj-10	60	3	initiate	initiate	VERB
gsrj-10	60	4	molecular	molecular	ADJ
gsrj-10	60	5	changes	change	NOUN
gsrj-10	60	6	which	which	PRON
gsrj-10	60	7	result	result	VERB
gsrj-10	60	8	in	in	ADP
gsrj-10	60	9	ampar	ampar	NOUN
gsrj-10	60	10	insertion	insertion	NOUN
gsrj-10	60	11	into	into	ADP
gsrj-10	60	12	vta	vta	PROPN
gsrj-10	60	13	da	da	PROPN
gsrj-10	60	14	neurons	neuron	NOUN
gsrj-10	60	15	,	,	PUNCT
gsrj-10	60	16	leading	lead	VERB
gsrj-10	60	17	to	to	ADP
gsrj-10	60	18	an	an	DET
gsrj-10	60	19	increase	increase	NOUN
gsrj-10	60	20	in	in	ADP
gsrj-10	60	21	the	the	DET
gsrj-10	60	22	firing	firing	NOUN
gsrj-10	60	23	rate	rate	NOUN
gsrj-10	60	24	of	of	ADP
gsrj-10	60	25	their	their	PRON
gsrj-10	60	26	neurons	neuron	NOUN
gsrj-10	60	27	and	and	CCONJ
gsrj-10	60	28	likely	likely	ADV
gsrj-10	60	29	mediate	mediate	VERB
gsrj-10	60	30	the	the	DET
gsrj-10	60	31	behavioral	behavioral	ADJ
gsrj-10	60	32	changes	change	NOUN
gsrj-10	60	33	associated	associate	VERB
gsrj-10	60	34	with	with	ADP
gsrj-10	60	35	stress	stress	NOUN
gsrj-10	60	36	.	.	PUNCT
gsrj-10	61	1	being	be	AUX
gsrj-10	61	2	that	that	SCONJ
gsrj-10	61	3	these	these	DET
gsrj-10	61	4	neurons	neuron	NOUN
gsrj-10	61	5	are	be	AUX
gsrj-10	61	6	highly	highly	ADV
gsrj-10	61	7	implicated	implicate	VERB
gsrj-10	61	8	in	in	ADP
gsrj-10	61	9	addiction	addiction	NOUN
gsrj-10	61	10	,	,	PUNCT
gsrj-10	61	11	ltp	ltp	PROPN
gsrj-10	61	12	at	at	ADP
gsrj-10	61	13	these	these	DET
gsrj-10	61	14	neurons	neuron	NOUN
gsrj-10	61	15	may	may	AUX
gsrj-10	61	16	also	also	ADV
gsrj-10	61	17	increase	increase	VERB
gsrj-10	61	18	the	the	DET
gsrj-10	61	19	susceptibility	susceptibility	NOUN
gsrj-10	61	20	of	of	ADP
gsrj-10	61	21	an	an	DET
gsrj-10	61	22	individual	individual	NOUN
gsrj-10	61	23	to	to	ADP
gsrj-10	61	24	addiction	addiction	NOUN
gsrj-10	61	25	,	,	PUNCT
gsrj-10	61	26	nicotine	nicotine	NOUN
gsrj-10	61	27	or	or	CCONJ
gsrj-10	61	28	otherwise	otherwise	ADV
gsrj-10	61	29	.	.	PUNCT
gsrj-10	62	1	this	this	PRON
gsrj-10	62	2	implicates	implicate	VERB
gsrj-10	62	3	stress	stress	NOUN
gsrj-10	62	4	as	as	ADP
gsrj-10	62	5	a	a	DET
gsrj-10	62	6	risk	risk	NOUN
gsrj-10	62	7	factor	factor	NOUN
gsrj-10	62	8	for	for	ADP
gsrj-10	62	9	addiction	addiction	NOUN
gsrj-10	62	10	and	and	CCONJ
gsrj-10	62	11	also	also	ADV
gsrj-10	62	12	implicates	implicate	VERB
gsrj-10	62	13	nicotine	nicotine	NOUN
gsrj-10	62	14	use	use	NOUN
gsrj-10	62	15	as	as	ADP
gsrj-10	62	16	a	a	DET
gsrj-10	62	17	risk	risk	NOUN
gsrj-10	62	18	factor	factor	NOUN
gsrj-10	62	19	for	for	ADP
gsrj-10	62	20	increases	increase	NOUN
gsrj-10	62	21	in	in	ADP
gsrj-10	62	22	stress	stress	ADJ
gsrj-10	62	23	response	response	NOUN
gsrj-10	62	24	and	and	CCONJ
gsrj-10	62	25	potentially	potentially	ADV
gsrj-10	62	26	mood	mood	NOUN
gsrj-10	62	27	dysregulation	dysregulation	NOUN
gsrj-10	62	28	.	.	PUNCT
gsrj-10	63	1	3	3	X
gsrj-10	63	2	.	.	X
gsrj-10	63	3	�	�	PROPN
gsrj-10	63	4	synaptic	synaptic	ADJ
gsrj-10	63	5	mechanisms	mechanism	NOUN
gsrj-10	63	6	:	:	PUNCT
gsrj-10	63	7	role	role	NOUN
gsrj-10	63	8	of	of	ADP
gsrj-10	63	9	ltp	ltp	PROPN
gsrj-10	63	10	in	in	ADP
gsrj-10	63	11	the	the	DET
gsrj-10	63	12	�	�	PROPN
gsrj-10	63	13	reward	reward	NOUN
gsrj-10	63	14	pathway	pathway	NOUN
gsrj-10	63	15	morel	morel	PROPN
gsrj-10	63	16	et	et	PROPN
gsrj-10	63	17	al	al	PROPN
gsrj-10	63	18	.	.	PROPN
gsrj-10	63	19	,	,	PUNCT
gsrj-10	63	20	2018	2018	NUM
gsrj-10	63	21	found	find	VERB
gsrj-10	63	22	that	that	SCONJ
gsrj-10	63	23	dopamine	dopamine	NOUN
gsrj-10	63	24	firing	firing	NOUN
gsrj-10	63	25	is	be	AUX
gsrj-10	63	26	likely	likely	ADV
gsrj-10	63	27	modulated	modulate	VERB
gsrj-10	63	28	through	through	ADP
gsrj-10	63	29	ltp	ltp	PROPN
gsrj-10	63	30	as	as	ADP
gsrj-10	63	31	a	a	DET
gsrj-10	63	32	response	response	NOUN
gsrj-10	63	33	to	to	PART
gsrj-10	63	34	nicotine	nicotine	VERB
gsrj-10	63	35	and/or	and/or	CCONJ
gsrj-10	63	36	stress	stress	NOUN
gsrj-10	63	37	.	.	PUNCT
gsrj-10	64	1	here	here	ADV
gsrj-10	64	2	,	,	PUNCT
gsrj-10	64	3	the	the	DET
gsrj-10	64	4	mechanisms	mechanism	NOUN
gsrj-10	64	5	of	of	ADP
gsrj-10	64	6	modulated	modulate	VERB
gsrj-10	64	7	dopamine	dopamine	NOUN
gsrj-10	64	8	firing	fire	VERB
gsrj-10	64	9	through	through	ADP
gsrj-10	64	10	ltp	ltp	PROPN
gsrj-10	64	11	are	be	AUX
gsrj-10	64	12	examined	examine	VERB
gsrj-10	64	13	.	.	PUNCT
gsrj-10	65	1	through	through	ADP
gsrj-10	65	2	this	this	DET
gsrj-10	65	3	mechanism	mechanism	NOUN
gsrj-10	65	4	,	,	PUNCT
gsrj-10	65	5	ltp	ltp	PROPN
gsrj-10	65	6	amplifies	amplify	VERB
gsrj-10	65	7	the	the	DET
gsrj-10	65	8	reward	reward	NOUN
gsrj-10	65	9	associated	associate	VERB
gsrj-10	65	10	with	with	ADP
gsrj-10	65	11	dopamine	dopamine	NOUN
gsrj-10	65	12	release	release	NOUN
gsrj-10	65	13	in	in	ADP
gsrj-10	65	14	the	the	DET
gsrj-10	65	15	mesolimbic	mesolimbic	ADJ
gsrj-10	65	16	pathway	pathway	NOUN
gsrj-10	65	17	.	.	PUNCT
gsrj-10	66	1	both	both	DET
gsrj-10	66	2	stress	stress	NOUN
gsrj-10	66	3	and	and	CCONJ
gsrj-10	66	4	nicotine	nicotine	NOUN
gsrj-10	66	5	affect	affect	VERB
gsrj-10	66	6	the	the	DET
gsrj-10	66	7	signaling	signal	VERB
gsrj-10	66	8	strength	strength	NOUN
gsrj-10	66	9	of	of	ADP
gsrj-10	66	10	excitatory	excitatory	NOUN
gsrj-10	66	11	and	and	CCONJ
gsrj-10	66	12	inhibitory	inhibitory	ADJ
gsrj-10	66	13	synapses	synapsis	NOUN
gsrj-10	66	14	on	on	ADP
gsrj-10	66	15	dopamine	dopamine	NOUN
gsrj-10	66	16	neurons	neuron	NOUN
gsrj-10	66	17	in	in	ADP
gsrj-10	66	18	the	the	DET
gsrj-10	66	19	vta	vta	PROPN
gsrj-10	66	20	through	through	ADP
gsrj-10	66	21	nmdar	nmdar	ADV
gsrj-10	66	22	-	-	PUNCT
gsrj-10	66	23	dependent	dependent	ADJ
gsrj-10	66	24	ltp	ltp	NOUN
gsrj-10	66	25	and	and	CCONJ
gsrj-10	66	26	gabaar	gabaar	NOUN
gsrj-10	66	27	-	-	PUNCT
gsrj-10	66	28	dependent	dependent	ADJ
gsrj-10	66	29	ltp	ltp	PROPN
gsrj-10	66	30	,	,	PUNCT
gsrj-10	66	31	respectively.12	respectively.12	PROPN
gsrj-10	66	32	,	,	PUNCT
gsrj-10	66	33	13	13	NUM
gsrj-10	66	34	the	the	DET
gsrj-10	66	35	mechanisms	mechanism	NOUN
gsrj-10	66	36	by	by	ADP
gsrj-10	66	37	which	which	PRON
gsrj-10	66	38	stress	stress	NOUN
gsrj-10	66	39	and	and	CCONJ
gsrj-10	66	40	nicotine	nicotine	NOUN
gsrj-10	66	41	alter	alter	VERB
gsrj-10	66	42	these	these	DET
gsrj-10	66	43	pathways	pathway	NOUN
gsrj-10	66	44	are	be	AUX
gsrj-10	66	45	very	very	ADV
gsrj-10	66	46	different	different	ADJ
gsrj-10	66	47	,	,	PUNCT
gsrj-10	66	48	but	but	CCONJ
gsrj-10	66	49	these	these	DET
gsrj-10	66	50	same	same	ADJ
gsrj-10	66	51	pathways	pathway	NOUN
gsrj-10	66	52	play	play	VERB
gsrj-10	66	53	a	a	DET
gsrj-10	66	54	large	large	ADJ
gsrj-10	66	55	role	role	NOUN
gsrj-10	66	56	in	in	ADP
gsrj-10	66	57	addiction	addiction	NOUN
gsrj-10	66	58	and	and	CCONJ
gsrj-10	66	59	reward	reward	NOUN
gsrj-10	66	60	association	association	PROPN
gsrj-10	66	61	.	.	PUNCT
gsrj-10	67	1	nmdar	nmdar	PROPN
gsrj-10	67	2	-	-	PUNCT
gsrj-10	67	3	dependent	dependent	ADJ
gsrj-10	67	4	ltp	ltp	PROPN
gsrj-10	67	5	is	be	AUX
gsrj-10	67	6	crucial	crucial	ADJ
gsrj-10	67	7	for	for	ADP
gsrj-10	67	8	increasing	increase	VERB
gsrj-10	67	9	the	the	DET
gsrj-10	67	10	strength	strength	NOUN
gsrj-10	67	11	of	of	ADP
gsrj-10	67	12	excitatory	excitatory	ADJ
gsrj-10	67	13	synapses	synapsis	NOUN
gsrj-10	67	14	.	.	PUNCT
gsrj-10	68	1	glutamate	glutamate	VERB
gsrj-10	68	2	signaling	signal	VERB
gsrj-10	68	3	on	on	ADP
gsrj-10	68	4	dopaminergic	dopaminergic	ADJ
gsrj-10	68	5	neurons	neuron	NOUN
gsrj-10	68	6	in	in	ADP
gsrj-10	68	7	the	the	DET
gsrj-10	68	8	vta	vta	PROPN
gsrj-10	68	9	drives	drive	VERB
gsrj-10	68	10	this	this	DET
gsrj-10	68	11	process	process	NOUN
gsrj-10	68	12	through	through	ADP
gsrj-10	68	13	the	the	DET
gsrj-10	68	14	reinforcement	reinforcement	NOUN
gsrj-10	68	15	of	of	ADP
gsrj-10	68	16	excitatory	excitatory	NOUN
gsrj-10	68	17	synapses	synapsis	NOUN
gsrj-10	68	18	via	via	ADP
gsrj-10	68	19	insertion	insertion	NOUN
gsrj-10	68	20	75	75	NUM
gsrj-10	68	21	georgetown	georgetown	PROPN
gsrj-10	68	22	scientific	scientific	PROPN
gsrj-10	68	23	research	research	NOUN
gsrj-10	68	24	journal	journal	NOUN
gsrj-10	68	25	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	ADJ
gsrj-10	68	26	of	of	ADP
gsrj-10	68	27	ampars	ampar	NOUN
gsrj-10	68	28	postsynaptically.14	postsynaptically.14	PROPN
gsrj-10	68	29	this	this	DET
gsrj-10	68	30	ltp	ltp	PROPN
gsrj-10	68	31	pathway	pathway	NOUN
gsrj-10	68	32	involves	involve	VERB
gsrj-10	68	33	both	both	PRON
gsrj-10	68	34	ampar	ampar	NOUN
gsrj-10	68	35	subtype	subtype	NOUN
gsrj-10	68	36	glur1	glur1	PROPN
gsrj-10	68	37	and	and	CCONJ
gsrj-10	68	38	nmdars	nmdar	NOUN
gsrj-10	68	39	(	(	PUNCT
gsrj-10	68	40	figure	figure	NOUN
gsrj-10	68	41	4	4	NUM
gsrj-10	68	42	)	)	PUNCT
gsrj-10	68	43	.	.	PUNCT
gsrj-10	69	1	when	when	SCONJ
gsrj-10	69	2	glutamate	glutamate	NOUN
gsrj-10	69	3	is	be	AUX
gsrj-10	69	4	released	release	VERB
gsrj-10	69	5	from	from	ADP
gsrj-10	69	6	the	the	DET
gsrj-10	69	7	presynaptic	presynaptic	ADJ
gsrj-10	69	8	terminal	terminal	NOUN
gsrj-10	69	9	,	,	PUNCT
gsrj-10	69	10	it	it	PRON
gsrj-10	69	11	binds	bind	VERB
gsrj-10	69	12	to	to	ADP
gsrj-10	69	13	glur1	glur1	NOUN
gsrj-10	69	14	receptors	receptor	NOUN
gsrj-10	69	15	on	on	ADP
gsrj-10	69	16	the	the	DET
gsrj-10	69	17	postsynaptic	postsynaptic	ADJ
gsrj-10	69	18	terminal	terminal	NOUN
gsrj-10	69	19	.	.	PUNCT
gsrj-10	70	1	the	the	DET
gsrj-10	70	2	binding	binding	NOUN
gsrj-10	70	3	of	of	ADP
gsrj-10	70	4	glutamate	glutamate	NOUN
gsrj-10	70	5	onto	onto	ADP
gsrj-10	70	6	glur1	glur1	PROPN
gsrj-10	70	7	allows	allow	VERB
gsrj-10	70	8	the	the	DET
gsrj-10	70	9	influx	influx	NOUN
gsrj-10	70	10	of	of	ADP
gsrj-10	70	11	sodium	sodium	NOUN
gsrj-10	70	12	(	(	PUNCT
gsrj-10	70	13	na+	na+	NOUN
gsrj-10	70	14	)	)	PUNCT
gsrj-10	70	15	and	and	CCONJ
gsrj-10	70	16	potassium	potassium	NOUN
gsrj-10	70	17	(	(	PUNCT
gsrj-10	70	18	k+	k+	NOUN
gsrj-10	70	19	)	)	PUNCT
gsrj-10	70	20	,	,	PUNCT
gsrj-10	70	21	which	which	PRON
gsrj-10	70	22	depolarizes	depolarize	VERB
gsrj-10	70	23	the	the	DET
gsrj-10	70	24	postsynaptic	postsynaptic	ADJ
gsrj-10	70	25	cell	cell	NOUN
gsrj-10	70	26	.	.	PUNCT
gsrj-10	71	1	once	once	SCONJ
gsrj-10	71	2	the	the	DET
gsrj-10	71	3	membrane	membrane	NOUN
gsrj-10	71	4	is	be	AUX
gsrj-10	71	5	depolarized	depolarize	VERB
gsrj-10	71	6	,	,	PUNCT
gsrj-10	71	7	the	the	DET
gsrj-10	71	8	magnesium	magnesium	NOUN
gsrj-10	71	9	(	(	PUNCT
gsrj-10	71	10	mg2	mg2	PROPN
gsrj-10	71	11	+	+	NOUN
gsrj-10	71	12	)	)	PUNCT
gsrj-10	71	13	voltage	voltage	NOUN
gsrj-10	71	14	-	-	PUNCT
gsrj-10	71	15	dependent	dependent	ADJ
gsrj-10	71	16	block	block	NOUN
gsrj-10	71	17	on	on	ADP
gsrj-10	71	18	nmda	nmda	ADJ
gsrj-10	71	19	receptors	receptor	NOUN
gsrj-10	71	20	is	be	AUX
gsrj-10	71	21	released	release	VERB
gsrj-10	71	22	and	and	CCONJ
gsrj-10	71	23	glutamate	glutamate	VERB
gsrj-10	71	24	binds	bind	VERB
gsrj-10	71	25	to	to	ADP
gsrj-10	71	26	these	these	DET
gsrj-10	71	27	receptors	receptor	NOUN
gsrj-10	71	28	with	with	ADP
gsrj-10	71	29	the	the	DET
gsrj-10	71	30	help	help	NOUN
gsrj-10	71	31	of	of	ADP
gsrj-10	71	32	a	a	DET
gsrj-10	71	33	glycine	glycine	NOUN
gsrj-10	71	34	or	or	CCONJ
gsrj-10	71	35	serine	serine	NOUN
gsrj-10	71	36	cofactor	cofactor	NOUN
gsrj-10	71	37	.	.	PUNCT
gsrj-10	72	1	once	once	ADV
gsrj-10	72	2	glutamate	glutamate	ADJ
gsrj-10	72	3	binds	bind	VERB
gsrj-10	72	4	to	to	ADP
gsrj-10	72	5	nmda	nmda	VERB
gsrj-10	72	6	,	,	PUNCT
gsrj-10	72	7	there	there	PRON
gsrj-10	72	8	is	be	VERB
gsrj-10	72	9	an	an	DET
gsrj-10	72	10	intracellular	intracellular	ADJ
gsrj-10	72	11	influx	influx	NOUN
gsrj-10	72	12	of	of	ADP
gsrj-10	72	13	calcium	calcium	NOUN
gsrj-10	72	14	(	(	PUNCT
gsrj-10	72	15	ca2	ca2	PROPN
gsrj-10	72	16	+	+	PROPN
gsrj-10	72	17	)	)	PUNCT
gsrj-10	72	18	,	,	PUNCT
gsrj-10	72	19	which	which	PRON
gsrj-10	72	20	activates	activate	VERB
gsrj-10	72	21	ca2+/calmodulin	ca2+/calmodulin	NOUN
gsrj-10	72	22	-	-	PUNCT
gsrj-10	72	23	dependent	dependent	ADJ
gsrj-10	72	24	protein	protein	NOUN
gsrj-10	72	25	kinase	kinase	NOUN
gsrj-10	72	26	(	(	PUNCT
gsrj-10	72	27	camkii	camkii	PROPN
gsrj-10	72	28	)	)	PUNCT
gsrj-10	72	29	through	through	ADP
gsrj-10	72	30	ca2	ca2	PROPN
gsrj-10	72	31	+	+	NOUN
gsrj-10	72	32	-dependent	-dependent	ADJ
gsrj-10	72	33	autophosphorylation	autophosphorylation	NOUN
gsrj-10	72	34	.	.	PUNCT
gsrj-10	73	1	following	follow	VERB
gsrj-10	73	2	this	this	PRON
gsrj-10	73	3	,	,	PUNCT
gsrj-10	73	4	camkii	camkii	PROPN
gsrj-10	73	5	phosphorylates	phosphorylate	NOUN
gsrj-10	73	6	glur1	glur1	PROPN
gsrj-10	73	7	to	to	PART
gsrj-10	73	8	increase	increase	VERB
gsrj-10	73	9	conductance	conductance	NOUN
gsrj-10	73	10	and	and	CCONJ
gsrj-10	73	11	targets	target	NOUN
gsrj-10	73	12	stargazin	stargazin	NOUN
gsrj-10	73	13	-	-	PUNCT
gsrj-10	73	14	like	like	ADJ
gsrj-10	73	15	transmembrane	transmembrane	NOUN
gsrj-10	73	16	ampar	ampar	ADP
gsrj-10	73	17	regulatory	regulatory	ADJ
gsrj-10	73	18	protein	protein	NOUN
gsrj-10	73	19	in	in	ADP
gsrj-10	73	20	order	order	NOUN
gsrj-10	73	21	for	for	ADP
gsrj-10	73	22	ampa	ampa	NOUN
gsrj-10	73	23	localization	localization	NOUN
gsrj-10	73	24	and	and	CCONJ
gsrj-10	73	25	clustering	cluster	VERB
gsrj-10	73	26	to	to	PART
gsrj-10	73	27	occur	occur	VERB
gsrj-10	73	28	,	,	PUNCT
gsrj-10	73	29	leading	lead	VERB
gsrj-10	73	30	to	to	ADP
gsrj-10	73	31	an	an	DET
gsrj-10	73	32	increase	increase	NOUN
gsrj-10	73	33	in	in	ADP
gsrj-10	73	34	ampars	ampar	NOUN
gsrj-10	73	35	.	.	PUNCT
gsrj-10	74	1	figure	figure	VERB
gsrj-10	74	2	4	4	NUM
gsrj-10	74	3	.	.	PUNCT
gsrj-10	74	4	nmdar	nmdar	ADV
gsrj-10	74	5	-	-	PUNCT
gsrj-10	74	6	mediated	mediate	VERB
gsrj-10	74	7	ltp	ltp	NOUN
gsrj-10	74	8	pathway.15	pathway.15	NOUN
gsrj-10	74	9	,	,	PUNCT
gsrj-10	74	10	16	16	NUM
gsrj-10	74	11	(	(	PUNCT
gsrj-10	74	12	adapted	adapt	VERB
gsrj-10	74	13	from	from	ADP
gsrj-10	74	14	dr	dr	PROPN
gsrj-10	74	15	.	.	PROPN
gsrj-10	74	16	mann	mann	PROPN
gsrj-10	74	17	.	.	PUNCT
gsrj-10	74	18	)	)	PUNCT
gsrj-10	75	1	the	the	DET
gsrj-10	75	2	way	way	NOUN
gsrj-10	75	3	nicotine	nicotine	NOUN
gsrj-10	75	4	and	and	CCONJ
gsrj-10	75	5	stress	stress	NOUN
gsrj-10	75	6	contribute	contribute	VERB
gsrj-10	75	7	to	to	ADP
gsrj-10	75	8	this	this	DET
gsrj-10	75	9	ltp	ltp	PROPN
gsrj-10	75	10	pathway	pathway	NOUN
gsrj-10	75	11	differs	differ	VERB
gsrj-10	75	12	.	.	PUNCT
gsrj-10	76	1	in	in	ADP
gsrj-10	76	2	the	the	DET
gsrj-10	76	3	vta	vta	NOUN
gsrj-10	76	4	,	,	PUNCT
gsrj-10	76	5	some	some	DET
gsrj-10	76	6	nachrs	nachrs	ADJ
gsrj-10	76	7	are	be	AUX
gsrj-10	76	8	located	locate	VERB
gsrj-10	76	9	on	on	ADP
gsrj-10	76	10	the	the	DET
gsrj-10	76	11	presynaptic	presynaptic	ADJ
gsrj-10	76	12	terminals	terminal	NOUN
gsrj-10	76	13	of	of	ADP
gsrj-10	76	14	glutamatergic	glutamatergic	ADJ
gsrj-10	76	15	neurons.17	neurons.17	NOUN
gsrj-10	76	16	once	once	SCONJ
gsrj-10	76	17	nicotine	nicotine	NOUN
gsrj-10	76	18	binds	bind	VERB
gsrj-10	76	19	to	to	PART
gsrj-10	76	20	nachrs	nachrs	VERB
gsrj-10	76	21	on	on	ADP
gsrj-10	76	22	the	the	DET
gsrj-10	76	23	presynaptic	presynaptic	ADJ
gsrj-10	76	24	terminal	terminal	NOUN
gsrj-10	76	25	,	,	PUNCT
gsrj-10	76	26	it	it	PRON
gsrj-10	76	27	allows	allow	VERB
gsrj-10	76	28	for	for	ADP
gsrj-10	76	29	the	the	DET
gsrj-10	76	30	influx	influx	NOUN
gsrj-10	76	31	of	of	ADP
gsrj-10	76	32	na+	na+	NOUN
gsrj-10	76	33	and	and	CCONJ
gsrj-10	76	34	ca2	ca2	PROPN
gsrj-10	76	35	+	+	PROPN
gsrj-10	76	36	,	,	PUNCT
gsrj-10	76	37	which	which	PRON
gsrj-10	76	38	depolarizes	depolarize	VERB
gsrj-10	76	39	the	the	DET
gsrj-10	76	40	presynaptic	presynaptic	ADJ
gsrj-10	76	41	neuron	neuron	NOUN
gsrj-10	76	42	.	.	PUNCT
gsrj-10	77	1	depolarization	depolarization	NOUN
gsrj-10	77	2	causes	cause	VERB
gsrj-10	77	3	further	further	ADJ
gsrj-10	77	4	ca2	ca2	PROPN
gsrj-10	77	5	+	+	X
gsrj-10	77	6	influx	influx	NOUN
gsrj-10	77	7	,	,	PUNCT
gsrj-10	77	8	which	which	PRON
gsrj-10	77	9	mediates	mediate	VERB
gsrj-10	77	10	the	the	DET
gsrj-10	77	11	docking	docking	NOUN
gsrj-10	77	12	and	and	CCONJ
gsrj-10	77	13	release	release	NOUN
gsrj-10	77	14	of	of	ADP
gsrj-10	77	15	glutamate	glutamate	NOUN
gsrj-10	77	16	.	.	PUNCT
gsrj-10	78	1	following	follow	VERB
gsrj-10	78	2	its	its	PRON
gsrj-10	78	3	release	release	NOUN
gsrj-10	78	4	,	,	PUNCT
gsrj-10	78	5	glutamate	glutamate	VERB
gsrj-10	78	6	binds	bind	VERB
gsrj-10	78	7	to	to	ADP
gsrj-10	78	8	ampars	ampar	NOUN
gsrj-10	78	9	on	on	ADP
gsrj-10	78	10	the	the	DET
gsrj-10	78	11	postsynaptic	postsynaptic	ADJ
gsrj-10	78	12	membrane	membrane	NOUN
gsrj-10	78	13	of	of	ADP
gsrj-10	78	14	dopaminergic	dopaminergic	ADJ
gsrj-10	78	15	neurons	neuron	NOUN
gsrj-10	78	16	,	,	PUNCT
gsrj-10	78	17	leading	lead	VERB
gsrj-10	78	18	to	to	ADP
gsrj-10	78	19	nmdar	nmdar	ADV
gsrj-10	78	20	-	-	PUNCT
gsrj-10	78	21	mediated	mediate	VERB
gsrj-10	78	22	ltp	ltp	NOUN
gsrj-10	78	23	as	as	ADP
gsrj-10	78	24	described	describe	VERB
gsrj-10	78	25	previously.18	previously.18	PROPN
gsrj-10	78	26	�	�	PROPN
gsrj-10	78	27	�	�	PROPN
gsrj-10	78	28	�	�	PROPN
gsrj-10	78	29	�	�	PROPN
gsrj-10	78	30	�	�	PROPN
gsrj-10	78	31	for	for	ADP
gsrj-10	78	32	stress	stress	NOUN
gsrj-10	78	33	-	-	PUNCT
gsrj-10	78	34	induced	induce	VERB
gsrj-10	78	35	nmdar	nmdar	ADV
gsrj-10	78	36	-	-	PUNCT
gsrj-10	78	37	mediated	mediate	VERB
gsrj-10	78	38	ltp	ltp	NOUN
gsrj-10	78	39	,	,	PUNCT
gsrj-10	78	40	g	g	NOUN
gsrj-10	78	41	-	-	PUNCT
gsrj-10	78	42	protein	protein	NOUN
gsrj-10	78	43	coupled	couple	VERB
gsrj-10	78	44	(	(	PUNCT
gsrj-10	78	45	gpcrs	gpcrs	PROPN
gsrj-10	78	46	)	)	PUNCT
gsrj-10	78	47	glucocorticoid	glucocorticoid	ADJ
gsrj-10	78	48	receptor	receptor	NOUN
gsrj-10	78	49	(	(	PUNCT
gsrj-10	78	50	gr	gr	NOUN
gsrj-10	78	51	)	)	PUNCT
gsrj-10	78	52	signaling	signal	VERB
gsrj-10	78	53	is	be	AUX
gsrj-10	78	54	crucial.19	crucial.19	NOUN
gsrj-10	78	55	exposure	exposure	NOUN
gsrj-10	78	56	to	to	ADP
gsrj-10	78	57	acute	acute	ADJ
gsrj-10	78	58	stress	stress	NOUN
gsrj-10	79	1	leads	lead	VERB
gsrj-10	79	2	to	to	ADP
gsrj-10	79	3	a	a	DET
gsrj-10	79	4	sympathetic	sympathetic	ADJ
gsrj-10	79	5	nervous	nervous	ADJ
gsrj-10	79	6	system	system	NOUN
gsrj-10	79	7	response	response	NOUN
gsrj-10	79	8	in	in	ADP
gsrj-10	79	9	which	which	PRON
gsrj-10	79	10	adrenaline	adrenaline	NOUN
gsrj-10	79	11	is	be	AUX
gsrj-10	79	12	released	release	VERB
gsrj-10	79	13	from	from	ADP
gsrj-10	79	14	the	the	DET
gsrj-10	79	15	adrenal	adrenal	ADJ
gsrj-10	79	16	medulla.20	medulla.20	NOUN
gsrj-10	79	17	following	follow	VERB
gsrj-10	79	18	this	this	PRON
gsrj-10	79	19	,	,	PUNCT
gsrj-10	79	20	there	there	PRON
gsrj-10	79	21	is	be	VERB
gsrj-10	79	22	an	an	DET
gsrj-10	79	23	increase	increase	NOUN
gsrj-10	79	24	in	in	ADP
gsrj-10	79	25	noradrenaline	noradrenaline	ADJ
gsrj-10	79	26	(	(	PUNCT
gsrj-10	79	27	na	na	NOUN
gsrj-10	79	28	)	)	PUNCT
gsrj-10	79	29	in	in	ADP
gsrj-10	79	30	the	the	DET
gsrj-10	79	31	cns	cns	NOUN
gsrj-10	79	32	.	.	PUNCT
gsrj-10	80	1	with	with	ADP
gsrj-10	80	2	the	the	DET
gsrj-10	80	3	increase	increase	NOUN
gsrj-10	80	4	of	of	ADP
gsrj-10	80	5	na	na	NOUN
gsrj-10	80	6	in	in	ADP
gsrj-10	80	7	the	the	DET
gsrj-10	80	8	brain	brain	NOUN
gsrj-10	80	9	,	,	PUNCT
gsrj-10	80	10	corticotropin	corticotropin	NOUN
gsrj-10	80	11	-	-	PUNCT
gsrj-10	80	12	releasing	releasing	NOUN
gsrj-10	80	13	factor	factor	NOUN
gsrj-10	80	14	(	(	PUNCT
gsrj-10	80	15	crf	crf	NOUN
gsrj-10	80	16	)	)	PUNCT
gsrj-10	80	17	neurons	neuron	NOUN
gsrj-10	80	18	in	in	ADP
gsrj-10	80	19	the	the	DET
gsrj-10	80	20	hypothalamus	hypothalamus	NOUN
gsrj-10	80	21	are	be	AUX
gsrj-10	80	22	stimulated	stimulate	VERB
gsrj-10	80	23	,	,	PUNCT
gsrj-10	80	24	which	which	PRON
gsrj-10	80	25	stimulates	stimulate	VERB
gsrj-10	80	26	the	the	DET
gsrj-10	80	27	anterior	anterior	ADJ
gsrj-10	80	28	pituitary	pituitary	NOUN
gsrj-10	80	29	,	,	PUNCT
gsrj-10	80	30	and	and	CCONJ
gsrj-10	80	31	adrenocorticotropin	adrenocorticotropin	NOUN
gsrj-10	80	32	is	be	AUX
gsrj-10	80	33	released	release	VERB
gsrj-10	80	34	.	.	PUNCT
gsrj-10	81	1	this	this	DET
gsrj-10	81	2	activity	activity	NOUN
gsrj-10	81	3	in	in	ADP
gsrj-10	81	4	the	the	DET
gsrj-10	81	5	hypothalamic	hypothalamic	ADJ
gsrj-10	81	6	-	-	PUNCT
gsrj-10	81	7	pituitary	pituitary	ADJ
gsrj-10	81	8	-	-	PUNCT
gsrj-10	81	9	adrenal	adrenal	ADJ
gsrj-10	81	10	(	(	PUNCT
gsrj-10	81	11	hpa	hpa	NOUN
gsrj-10	81	12	)	)	PUNCT
gsrj-10	81	13	axis	axis	NOUN
gsrj-10	81	14	elicits	elicit	VERB
gsrj-10	81	15	the	the	DET
gsrj-10	81	16	release	release	NOUN
gsrj-10	81	17	of	of	ADP
gsrj-10	81	18	corticosteroids	corticosteroid	NOUN
gsrj-10	81	19	from	from	ADP
gsrj-10	81	20	the	the	DET
gsrj-10	81	21	adrenal	adrenal	ADJ
gsrj-10	81	22	cortex	cortex	NOUN
gsrj-10	81	23	into	into	ADP
gsrj-10	81	24	the	the	DET
gsrj-10	81	25	bloodstream	bloodstream	NOUN
gsrj-10	81	26	.	.	PUNCT
gsrj-10	82	1	these	these	DET
gsrj-10	82	2	corticosteroids	corticosteroid	NOUN
gsrj-10	82	3	can	can	AUX
gsrj-10	82	4	pass	pass	VERB
gsrj-10	82	5	through	through	ADP
gsrj-10	82	6	the	the	DET
gsrj-10	82	7	blood	blood	NOUN
gsrj-10	82	8	-	-	PUNCT
gsrj-10	82	9	brain	brain	NOUN
gsrj-10	82	10	barrier	barrier	NOUN
gsrj-10	82	11	,	,	PUNCT
gsrj-10	82	12	and	and	CCONJ
gsrj-10	82	13	once	once	ADV
gsrj-10	82	14	in	in	ADP
gsrj-10	82	15	the	the	DET
gsrj-10	82	16	brain	brain	NOUN
gsrj-10	82	17	,	,	PUNCT
gsrj-10	82	18	they	they	PRON
gsrj-10	82	19	bind	bind	VERB
gsrj-10	82	20	to	to	ADP
gsrj-10	82	21	grs	grs	PROPN
gsrj-10	82	22	.	.	PUNCT
gsrj-10	83	1	grs	grs	NUM
gsrj-10	83	2	in	in	ADP
gsrj-10	83	3	dopaminoceptive	dopaminoceptive	ADJ
gsrj-10	83	4	neurons	neuron	NOUN
gsrj-10	83	5	of	of	ADP
gsrj-10	83	6	the	the	DET
gsrj-10	83	7	nucleus	nucleus	NOUN
gsrj-10	83	8	accumbens	accumben	NOUN
gsrj-10	83	9	(	(	PUNCT
gsrj-10	83	10	nac	nac	PROPN
gsrj-10	83	11	)	)	PUNCT
gsrj-10	83	12	communicate	communicate	VERB
gsrj-10	83	13	with	with	ADP
gsrj-10	83	14	dopaminergic	dopaminergic	ADJ
gsrj-10	83	15	neurons	neuron	NOUN
gsrj-10	83	16	in	in	ADP
gsrj-10	83	17	the	the	DET
gsrj-10	83	18	vta	vta	NOUN
gsrj-10	83	19	through	through	ADP
gsrj-10	83	20	glutamatergic	glutamatergic	ADJ
gsrj-10	83	21	interneurons.21	interneurons.21	NOUN
gsrj-10	83	22	when	when	SCONJ
gsrj-10	83	23	the	the	DET
gsrj-10	83	24	corticoids	corticoid	NOUN
gsrj-10	83	25	bind	bind	VERB
gsrj-10	83	26	to	to	ADP
gsrj-10	83	27	these	these	DET
gsrj-10	83	28	grs	grs	PROPN
gsrj-10	83	29	on	on	ADP
gsrj-10	83	30	dopaminoceptive	dopaminoceptive	ADJ
gsrj-10	83	31	neurons	neuron	NOUN
gsrj-10	83	32	,	,	PUNCT
gsrj-10	83	33	glutamate	glutamate	ADJ
gsrj-10	83	34	release	release	NOUN
gsrj-10	83	35	through	through	ADP
gsrj-10	83	36	this	this	DET
gsrj-10	83	37	positive	positive	ADJ
gsrj-10	83	38	feedback	feedback	NOUN
gsrj-10	83	39	pathway	pathway	NOUN
gsrj-10	83	40	excites	excite	VERB
gsrj-10	83	41	the	the	DET
gsrj-10	83	42	dopaminergic	dopaminergic	ADJ
gsrj-10	83	43	neurons	neuron	NOUN
gsrj-10	83	44	in	in	ADP
gsrj-10	83	45	the	the	DET
gsrj-10	83	46	vta	vta	NOUN
gsrj-10	83	47	,	,	PUNCT
gsrj-10	83	48	which	which	PRON
gsrj-10	83	49	when	when	SCONJ
gsrj-10	83	50	stimulated	stimulate	VERB
gsrj-10	83	51	leads	lead	VERB
gsrj-10	83	52	to	to	ADP
gsrj-10	83	53	ltp	ltp	PROPN
gsrj-10	83	54	.	.	PUNCT
gsrj-10	84	1	while	while	SCONJ
gsrj-10	84	2	nicotine	nicotine	NOUN
gsrj-10	84	3	and	and	CCONJ
gsrj-10	84	4	stress	stress	NOUN
gsrj-10	84	5	both	both	PRON
gsrj-10	84	6	increase	increase	VERB
gsrj-10	84	7	da	da	PROPN
gsrj-10	84	8	vta	vta	PROPN
gsrj-10	84	9	firing	firing	NOUN
gsrj-10	84	10	,	,	PUNCT
gsrj-10	84	11	nicotine	nicotine	NOUN
gsrj-10	84	12	acts	act	VERB
gsrj-10	84	13	quickly	quickly	ADV
gsrj-10	84	14	through	through	ADP
gsrj-10	84	15	an	an	DET
gsrj-10	84	16	ionotropic	ionotropic	ADJ
gsrj-10	84	17	receptor	receptor	NOUN
gsrj-10	84	18	while	while	SCONJ
gsrj-10	84	19	stress	stress	NOUN
gsrj-10	84	20	acts	act	VERB
gsrj-10	84	21	slower	slow	ADV
gsrj-10	84	22	on	on	ADP
gsrj-10	84	23	a	a	DET
gsrj-10	84	24	metabotropic	metabotropic	NOUN
gsrj-10	84	25	receptor	receptor	NOUN
gsrj-10	84	26	that	that	PRON
gsrj-10	84	27	requires	require	VERB
gsrj-10	84	28	many	many	ADJ
gsrj-10	84	29	different	different	ADJ
gsrj-10	84	30	neuroendocrine	neuroendocrine	NOUN
gsrj-10	84	31	pathways	pathway	NOUN
gsrj-10	84	32	.	.	PUNCT
gsrj-10	85	1	conversely	conversely	ADV
gsrj-10	85	2	,	,	PUNCT
gsrj-10	85	3	both	both	PRON
gsrj-10	85	4	nicotine	nicotine	VERB
gsrj-10	85	5	and	and	CCONJ
gsrj-10	85	6	stress	stress	NOUN
gsrj-10	85	7	inhibit	inhibit	NOUN
gsrj-10	85	8	gabaar	gabaar	NOUN
gsrj-10	85	9	-	-	PUNCT
gsrj-10	85	10	mediated	mediate	VERB
gsrj-10	85	11	ltp	ltp	NOUN
gsrj-10	85	12	,	,	PUNCT
gsrj-10	85	13	which	which	PRON
gsrj-10	85	14	leads	lead	VERB
gsrj-10	85	15	to	to	ADP
gsrj-10	85	16	decreased	decrease	VERB
gsrj-10	85	17	inhibition	inhibition	NOUN
gsrj-10	85	18	of	of	ADP
gsrj-10	85	19	dopaminergic	dopaminergic	ADJ
gsrj-10	85	20	neurons	neuron	NOUN
gsrj-10	85	21	in	in	ADP
gsrj-10	85	22	the	the	DET
gsrj-10	85	23	vta	vta	PROPN
gsrj-10	85	24	(	(	PUNCT
gsrj-10	85	25	figure	figure	NOUN
gsrj-10	85	26	5	5	NUM
gsrj-10	85	27	)	)	PUNCT
gsrj-10	85	28	.	.	PUNCT
gsrj-10	86	1	this	this	DET
gsrj-10	86	2	form	form	NOUN
gsrj-10	86	3	of	of	ADP
gsrj-10	86	4	ltp	ltp	PROPN
gsrj-10	86	5	is	be	AUX
gsrj-10	86	6	characterized	characterize	VERB
gsrj-10	86	7	by	by	ADP
gsrj-10	86	8	an	an	DET
gsrj-10	86	9	enhancement	enhancement	NOUN
gsrj-10	86	10	of	of	ADP
gsrj-10	86	11	inhibitory	inhibitory	ADJ
gsrj-10	86	12	postsynaptic	postsynaptic	ADJ
gsrj-10	86	13	potentials	potential	NOUN
gsrj-10	86	14	(	(	PUNCT
gsrj-10	86	15	ipsp	ipsp	NOUN
gsrj-10	86	16	)	)	PUNCT
gsrj-10	86	17	via	via	ADP
gsrj-10	86	18	increased	increase	VERB
gsrj-10	86	19	76	76	NUM
gsrj-10	86	20	georgetown	georgetown	PROPN
gsrj-10	86	21	scientific	scientific	PROPN
gsrj-10	86	22	research	research	NOUN
gsrj-10	86	23	journal	journal	PROPN
gsrj-10	86	24	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	86	25	gaba	gaba	PROPN
gsrj-10	86	26	release.22	release.22	NOUN
gsrj-10	86	27	when	when	SCONJ
gsrj-10	86	28	gabaergic	gabaergic	ADJ
gsrj-10	86	29	neurons	neuron	NOUN
gsrj-10	86	30	release	release	VERB
gsrj-10	86	31	gaba	gaba	NOUN
gsrj-10	86	32	from	from	ADP
gsrj-10	86	33	their	their	PRON
gsrj-10	86	34	presynaptic	presynaptic	ADJ
gsrj-10	86	35	terminals	terminal	NOUN
gsrj-10	86	36	,	,	PUNCT
gsrj-10	86	37	gaba	gaba	PROPN
gsrj-10	86	38	binds	bind	VERB
gsrj-10	86	39	to	to	ADP
gsrj-10	86	40	gabaars	gabaar	NOUN
gsrj-10	86	41	on	on	ADP
gsrj-10	86	42	the	the	DET
gsrj-10	86	43	postsynaptic	postsynaptic	ADJ
gsrj-10	86	44	terminals	terminal	NOUN
gsrj-10	86	45	of	of	ADP
gsrj-10	86	46	dopaminergic	dopaminergic	ADJ
gsrj-10	86	47	neurons	neuron	NOUN
gsrj-10	86	48	in	in	ADP
gsrj-10	86	49	the	the	DET
gsrj-10	86	50	vta	vta	NOUN
gsrj-10	86	51	,	,	PUNCT
gsrj-10	86	52	hyperpolarizing	hyperpolarize	VERB
gsrj-10	86	53	these	these	DET
gsrj-10	86	54	neurons	neuron	NOUN
gsrj-10	86	55	via	via	ADP
gsrj-10	86	56	an	an	DET
gsrj-10	86	57	influx	influx	NOUN
gsrj-10	86	58	of	of	ADP
gsrj-10	86	59	intracellular	intracellular	ADJ
gsrj-10	86	60	chloride	chloride	NOUN
gsrj-10	86	61	(	(	PUNCT
gsrj-10	86	62	cl-	cl-	NUM
gsrj-10	86	63	)	)	PUNCT
gsrj-10	86	64	.	.	PUNCT
gsrj-10	87	1	following	follow	VERB
gsrj-10	87	2	numerous	numerous	ADJ
gsrj-10	87	3	ipsps	ipsp	NOUN
gsrj-10	87	4	,	,	PUNCT
gsrj-10	87	5	there	there	PRON
gsrj-10	87	6	is	be	VERB
gsrj-10	87	7	a	a	DET
gsrj-10	87	8	rebound	rebound	NOUN
gsrj-10	87	9	depolarization	depolarization	NOUN
gsrj-10	87	10	of	of	ADP
gsrj-10	87	11	the	the	DET
gsrj-10	87	12	membrane	membrane	NOUN
gsrj-10	87	13	,	,	PUNCT
gsrj-10	87	14	and	and	CCONJ
gsrj-10	87	15	,	,	PUNCT
gsrj-10	87	16	subsequently	subsequently	ADV
gsrj-10	87	17	,	,	PUNCT
gsrj-10	87	18	voltage	voltage	NOUN
gsrj-10	87	19	-	-	PUNCT
gsrj-10	87	20	gated	gate	VERB
gsrj-10	87	21	ca2	ca2	PROPN
gsrj-10	87	22	+	+	NOUN
gsrj-10	87	23	channels	channel	NOUN
gsrj-10	87	24	(	(	PUNCT
gsrj-10	87	25	vgcc	vgcc	NOUN
gsrj-10	87	26	)	)	PUNCT
gsrj-10	87	27	on	on	ADP
gsrj-10	87	28	the	the	DET
gsrj-10	87	29	dendrite	dendrite	NOUN
gsrj-10	87	30	are	be	AUX
gsrj-10	87	31	activated	activate	VERB
gsrj-10	87	32	.	.	PUNCT
gsrj-10	88	1	with	with	ADP
gsrj-10	88	2	the	the	DET
gsrj-10	88	3	activation	activation	NOUN
gsrj-10	88	4	of	of	ADP
gsrj-10	88	5	vgccs	vgccs	NOUN
gsrj-10	88	6	,	,	PUNCT
gsrj-10	88	7	there	there	PRON
gsrj-10	88	8	is	be	VERB
gsrj-10	88	9	an	an	DET
gsrj-10	88	10	influx	influx	NOUN
gsrj-10	88	11	of	of	ADP
gsrj-10	88	12	ca2	ca2	PROPN
gsrj-10	88	13	+	+	PROPN
gsrj-10	88	14	.	.	PUNCT
gsrj-10	89	1	furthermore	furthermore	ADV
gsrj-10	89	2	,	,	PUNCT
gsrj-10	89	3	when	when	SCONJ
gsrj-10	89	4	glutamate	glutamate	NOUN
gsrj-10	89	5	activates	activate	VERB
gsrj-10	89	6	nmdars	nmdar	NOUN
gsrj-10	89	7	,	,	PUNCT
gsrj-10	89	8	gabaars	gabaar	NOUN
gsrj-10	89	9	in	in	ADP
gsrj-10	89	10	neighboring	neighboring	NOUN
gsrj-10	89	11	synapses	synapsis	NOUN
gsrj-10	89	12	may	may	AUX
gsrj-10	89	13	be	be	AUX
gsrj-10	89	14	potentiated	potentiate	VERB
gsrj-10	89	15	.	.	PUNCT
gsrj-10	90	1	the	the	DET
gsrj-10	90	2	influx	influx	NOUN
gsrj-10	90	3	of	of	ADP
gsrj-10	90	4	ca2	ca2	PROPN
gsrj-10	90	5	+	+	PROPN
gsrj-10	90	6	is	be	AUX
gsrj-10	90	7	crucial	crucial	ADJ
gsrj-10	90	8	for	for	ADP
gsrj-10	90	9	the	the	DET
gsrj-10	90	10	mechanism	mechanism	NOUN
gsrj-10	90	11	of	of	ADP
gsrj-10	90	12	ltp	ltp	PROPN
gsrj-10	90	13	.	.	PUNCT
gsrj-10	91	1	it	it	PRON
gsrj-10	91	2	is	be	AUX
gsrj-10	91	3	suspected	suspect	VERB
gsrj-10	91	4	that	that	SCONJ
gsrj-10	91	5	this	this	DET
gsrj-10	91	6	increase	increase	NOUN
gsrj-10	91	7	of	of	ADP
gsrj-10	91	8	intracellular	intracellular	ADJ
gsrj-10	91	9	ca2	ca2	PROPN
gsrj-10	91	10	+	+	PROPN
gsrj-10	91	11	leads	lead	VERB
gsrj-10	91	12	to	to	ADP
gsrj-10	91	13	the	the	DET
gsrj-10	91	14	release	release	NOUN
gsrj-10	91	15	of	of	ADP
gsrj-10	91	16	nitric	nitric	ADJ
gsrj-10	91	17	oxide	oxide	NOUN
gsrj-10	91	18	(	(	PUNCT
gsrj-10	91	19	no	no	NOUN
gsrj-10	91	20	)	)	PUNCT
gsrj-10	91	21	,	,	PUNCT
gsrj-10	91	22	a	a	DET
gsrj-10	91	23	retrograde	retrograde	ADJ
gsrj-10	91	24	messenger	messenger	NOUN
gsrj-10	91	25	.	.	PUNCT
gsrj-10	92	1	no	no	PRON
gsrj-10	92	2	activates	activate	VERB
gsrj-10	92	3	presynaptic	presynaptic	ADJ
gsrj-10	92	4	soluble	soluble	ADJ
gsrj-10	92	5	guanylate	guanylate	NOUN
gsrj-10	92	6	cyclase	cyclase	NOUN
gsrj-10	92	7	,	,	PUNCT
gsrj-10	92	8	which	which	PRON
gsrj-10	92	9	produces	produce	VERB
gsrj-10	92	10	cyclic	cyclic	ADJ
gsrj-10	92	11	guanosine	guanosine	NOUN
gsrj-10	92	12	monophosphate	monophosphate	NOUN
gsrj-10	92	13	(	(	PUNCT
gsrj-10	92	14	cgmp	cgmp	PROPN
gsrj-10	92	15	)	)	PUNCT
gsrj-10	92	16	.	.	PUNCT
gsrj-10	93	1	cgmp	cgmp	PROPN
gsrj-10	93	2	activates	activate	VERB
gsrj-10	93	3	the	the	DET
gsrj-10	93	4	cgmp	cgmp	ADJ
gsrj-10	93	5	-	-	ADJ
gsrj-10	93	6	dependent	dependent	ADJ
gsrj-10	93	7	protein	protein	NOUN
gsrj-10	93	8	kinase	kinase	NOUN
gsrj-10	93	9	,	,	PUNCT
gsrj-10	93	10	which	which	PRON
gsrj-10	93	11	increases	increase	VERB
gsrj-10	93	12	gaba	gaba	PROPN
gsrj-10	93	13	release	release	NOUN
gsrj-10	93	14	from	from	ADP
gsrj-10	93	15	the	the	DET
gsrj-10	93	16	presynaptic	presynaptic	ADJ
gsrj-10	93	17	neuron	neuron	NOUN
gsrj-10	93	18	.	.	PUNCT
gsrj-10	94	1	when	when	SCONJ
gsrj-10	94	2	this	this	DET
gsrj-10	94	3	type	type	NOUN
gsrj-10	94	4	of	of	ADP
gsrj-10	94	5	ltp	ltp	PROPN
gsrj-10	94	6	is	be	AUX
gsrj-10	94	7	inhibited	inhibit	VERB
gsrj-10	94	8	,	,	PUNCT
gsrj-10	94	9	gaba	gaba	PROPN
gsrj-10	94	10	release	release	NOUN
gsrj-10	94	11	decreases	decrease	NOUN
gsrj-10	94	12	,	,	PUNCT
gsrj-10	94	13	resulting	result	VERB
gsrj-10	94	14	in	in	ADP
gsrj-10	94	15	less	less	ADJ
gsrj-10	94	16	inhibition	inhibition	NOUN
gsrj-10	94	17	on	on	ADP
gsrj-10	94	18	da	da	ADJ
gsrj-10	94	19	neurons	neuron	NOUN
gsrj-10	94	20	in	in	ADP
gsrj-10	94	21	the	the	DET
gsrj-10	94	22	vta	vta	PROPN
gsrj-10	94	23	.	.	PUNCT
gsrj-10	95	1	research	research	NOUN
gsrj-10	95	2	shows	show	VERB
gsrj-10	95	3	that	that	SCONJ
gsrj-10	95	4	there	there	PRON
gsrj-10	95	5	is	be	VERB
gsrj-10	95	6	an	an	DET
gsrj-10	95	7	impairment	impairment	NOUN
gsrj-10	95	8	of	of	ADP
gsrj-10	95	9	this	this	DET
gsrj-10	95	10	form	form	NOUN
gsrj-10	95	11	of	of	ADP
gsrj-10	95	12	ltp	ltp	PROPN
gsrj-10	95	13	following	follow	VERB
gsrj-10	95	14	the	the	DET
gsrj-10	95	15	injection	injection	NOUN
gsrj-10	95	16	of	of	ADP
gsrj-10	95	17	nicotine	nicotine	NOUN
gsrj-10	95	18	and	and	CCONJ
gsrj-10	95	19	acute	acute	ADJ
gsrj-10	95	20	stress	stress	NOUN
gsrj-10	95	21	.	.	PUNCT
gsrj-10	96	1	figure	figure	NOUN
gsrj-10	96	2	5	5	NUM
gsrj-10	96	3	.	.	PUNCT
gsrj-10	96	4	gabaar	gabaar	NOUN
gsrj-10	96	5	-	-	PUNCT
gsrj-10	96	6	mediated	mediate	VERB
gsrj-10	96	7	ltp	ltp	NOUN
gsrj-10	96	8	pathway.23	pathway.23	PROPN
gsrj-10	96	9	(	(	PUNCT
gsrj-10	96	10	adapted	adapt	VERB
gsrj-10	96	11	from	from	ADP
gsrj-10	96	12	govindpani	govindpani	PROPN
gsrj-10	96	13	et	et	PROPN
gsrj-10	96	14	al	al	PROPN
gsrj-10	96	15	.	.	PROPN
gsrj-10	96	16	)	)	PUNCT
gsrj-10	97	1	the	the	DET
gsrj-10	97	2	mechanism	mechanism	NOUN
gsrj-10	97	3	by	by	ADP
gsrj-10	97	4	which	which	PRON
gsrj-10	97	5	nicotine	nicotine	NOUN
gsrj-10	97	6	and	and	CCONJ
gsrj-10	97	7	stress	stress	NOUN
gsrj-10	97	8	lead	lead	NOUN
gsrj-10	97	9	to	to	ADP
gsrj-10	97	10	inhibition	inhibition	NOUN
gsrj-10	97	11	of	of	ADP
gsrj-10	97	12	gabaar	gabaar	NOUN
gsrj-10	97	13	-	-	PUNCT
gsrj-10	97	14	mediated	mediate	VERB
gsrj-10	97	15	ltp	ltp	NOUN
gsrj-10	97	16	is	be	AUX
gsrj-10	97	17	not	not	PART
gsrj-10	97	18	completely	completely	ADV
gsrj-10	97	19	known	know	VERB
gsrj-10	97	20	.	.	PUNCT
gsrj-10	98	1	α7	α7	NOUN
gsrj-10	98	2	-	-	PUNCT
gsrj-10	98	3	containing	contain	VERB
gsrj-10	98	4	nachrs	nachrs	ADV
gsrj-10	98	5	are	be	AUX
gsrj-10	98	6	localized	localize	VERB
gsrj-10	98	7	on	on	ADP
gsrj-10	98	8	the	the	DET
gsrj-10	98	9	presynaptic	presynaptic	ADJ
gsrj-10	98	10	terminals	terminal	NOUN
gsrj-10	98	11	of	of	ADP
gsrj-10	98	12	gabaergic	gabaergic	ADJ
gsrj-10	98	13	neurons	neuron	NOUN
gsrj-10	98	14	in	in	ADP
gsrj-10	98	15	the	the	DET
gsrj-10	98	16	vta.13	vta.13	NOUN
gsrj-10	98	17	when	when	SCONJ
gsrj-10	98	18	nicotine	nicotine	NOUN
gsrj-10	98	19	binds	bind	VERB
gsrj-10	98	20	to	to	ADP
gsrj-10	98	21	these	these	DET
gsrj-10	98	22	nachrs	nachrs	ADJ
gsrj-10	98	23	,	,	PUNCT
gsrj-10	98	24	the	the	DET
gsrj-10	98	25	gabaergic	gabaergic	ADJ
gsrj-10	98	26	presynaptic	presynaptic	ADJ
gsrj-10	98	27	terminals	terminal	NOUN
gsrj-10	98	28	desensitize	desensitize	VERB
gsrj-10	98	29	quickly	quickly	ADV
gsrj-10	98	30	.	.	PUNCT
gsrj-10	99	1	this	this	PRON
gsrj-10	99	2	leads	lead	VERB
gsrj-10	99	3	to	to	ADP
gsrj-10	99	4	less	less	ADJ
gsrj-10	99	5	release	release	NOUN
gsrj-10	99	6	of	of	ADP
gsrj-10	99	7	gaba	gaba	NOUN
gsrj-10	99	8	,	,	PUNCT
gsrj-10	99	9	which	which	PRON
gsrj-10	99	10	inhibits	inhibit	VERB
gsrj-10	99	11	the	the	DET
gsrj-10	99	12	ltp	ltp	PROPN
gsrj-10	99	13	pathway	pathway	NOUN
gsrj-10	99	14	on	on	ADP
gsrj-10	99	15	postsynaptic	postsynaptic	ADJ
gsrj-10	99	16	terminals	terminal	NOUN
gsrj-10	99	17	of	of	ADP
gsrj-10	99	18	da	da	ADJ
gsrj-10	99	19	neurons	neuron	NOUN
gsrj-10	99	20	in	in	ADP
gsrj-10	99	21	the	the	DET
gsrj-10	99	22	vta	vta	PROPN
gsrj-10	99	23	.	.	PUNCT
gsrj-10	100	1	for	for	ADP
gsrj-10	100	2	acute	acute	ADJ
gsrj-10	100	3	stress	stress	NOUN
gsrj-10	100	4	,	,	PUNCT
gsrj-10	100	5	the	the	DET
gsrj-10	100	6	glucocorticoid	glucocorticoid	ADJ
gsrj-10	100	7	pathway	pathway	NOUN
gsrj-10	100	8	described	describe	VERB
gsrj-10	100	9	in	in	ADP
gsrj-10	100	10	nmdarmediated	nmdarmediate	VERB
gsrj-10	100	11	ltp	ltp	PROPN
gsrj-10	100	12	contributes	contribute	VERB
gsrj-10	100	13	to	to	ADP
gsrj-10	100	14	reduced	reduce	VERB
gsrj-10	100	15	gaba	gaba	PROPN
gsrj-10	100	16	firing.24	firing.24	NOUN
gsrj-10	100	17	the	the	DET
gsrj-10	100	18	initial	initial	ADJ
gsrj-10	100	19	response	response	NOUN
gsrj-10	100	20	to	to	ADP
gsrj-10	100	21	this	this	DET
gsrj-10	100	22	acute	acute	NOUN
gsrj-10	100	23	stress	stress	NOUN
gsrj-10	100	24	is	be	AUX
gsrj-10	100	25	an	an	DET
gsrj-10	100	26	increase	increase	NOUN
gsrj-10	100	27	in	in	ADP
gsrj-10	100	28	gaba	gaba	NOUN
gsrj-10	100	29	firing	fire	VERB
gsrj-10	100	30	mediated	mediate	VERB
gsrj-10	100	31	through	through	ADP
gsrj-10	100	32	the	the	DET
gsrj-10	100	33	no	no	DET
gsrj-10	100	34	-	-	PUNCT
gsrj-10	100	35	cgmp	cgmp	NOUN
gsrj-10	100	36	-	-	PUNCT
gsrj-10	100	37	pkg	pkg	NOUN
gsrj-10	100	38	pathway	pathway	NOUN
gsrj-10	100	39	,	,	PUNCT
gsrj-10	100	40	but	but	CCONJ
gsrj-10	100	41	the	the	DET
gsrj-10	100	42	long	long	ADJ
gsrj-10	100	43	-	-	PUNCT
gsrj-10	100	44	term	term	NOUN
gsrj-10	100	45	effect	effect	NOUN
gsrj-10	100	46	of	of	ADP
gsrj-10	100	47	this	this	DET
gsrj-10	100	48	acute	acute	NOUN
gsrj-10	100	49	stress	stress	NOUN
gsrj-10	100	50	is	be	AUX
gsrj-10	100	51	an	an	DET
gsrj-10	100	52	inhibition	inhibition	NOUN
gsrj-10	100	53	in	in	ADP
gsrj-10	100	54	this	this	DET
gsrj-10	100	55	form	form	NOUN
gsrj-10	100	56	of	of	ADP
gsrj-10	100	57	ltp	ltp	PROPN
gsrj-10	100	58	.	.	PUNCT
gsrj-10	101	1	after	after	ADP
gsrj-10	101	2	sustained	sustained	ADJ
gsrj-10	101	3	hyperpolarization	hyperpolarization	NOUN
gsrj-10	101	4	,	,	PUNCT
gsrj-10	101	5	there	there	PRON
gsrj-10	101	6	is	be	VERB
gsrj-10	101	7	a	a	DET
gsrj-10	101	8	shift	shift	NOUN
gsrj-10	101	9	in	in	ADP
gsrj-10	101	10	clreversal	clreversal	ADJ
gsrj-10	101	11	potential	potential	NOUN
gsrj-10	101	12	,	,	PUNCT
gsrj-10	101	13	making	make	VERB
gsrj-10	101	14	gaba	gaba	NOUN
gsrj-10	101	15	become	become	VERB
gsrj-10	101	16	excitatory	excitatory	ADJ
gsrj-10	101	17	rather	rather	ADV
gsrj-10	101	18	than	than	ADP
gsrj-10	101	19	inhibitory	inhibitory	ADJ
gsrj-10	101	20	.	.	PUNCT
gsrj-10	102	1	although	although	SCONJ
gsrj-10	102	2	more	more	ADJ
gsrj-10	102	3	research	research	NOUN
gsrj-10	102	4	needs	need	VERB
gsrj-10	102	5	to	to	PART
gsrj-10	102	6	be	be	AUX
gsrj-10	102	7	performed	perform	VERB
gsrj-10	102	8	to	to	PART
gsrj-10	102	9	elucidate	elucidate	VERB
gsrj-10	102	10	the	the	DET
gsrj-10	102	11	specific	specific	ADJ
gsrj-10	102	12	pathway	pathway	NOUN
gsrj-10	102	13	,	,	PUNCT
gsrj-10	102	14	both	both	PRON
gsrj-10	102	15	nicotine	nicotine	VERB
gsrj-10	102	16	and	and	CCONJ
gsrj-10	102	17	stress	stress	NOUN
gsrj-10	102	18	affect	affect	VERB
gsrj-10	102	19	this	this	DET
gsrj-10	102	20	ltp	ltp	PROPN
gsrj-10	102	21	pathway	pathway	NOUN
gsrj-10	102	22	.	.	PUNCT
gsrj-10	103	1	these	these	DET
gsrj-10	103	2	two	two	NUM
gsrj-10	103	3	ltp	ltp	PROPN
gsrj-10	103	4	neural	neural	ADJ
gsrj-10	103	5	mechanisms	mechanism	NOUN
gsrj-10	103	6	play	play	VERB
gsrj-10	103	7	a	a	DET
gsrj-10	103	8	key	key	ADJ
gsrj-10	103	9	role	role	NOUN
gsrj-10	103	10	in	in	ADP
gsrj-10	103	11	how	how	SCONJ
gsrj-10	103	12	nicotine	nicotine	NOUN
gsrj-10	103	13	and	and	CCONJ
gsrj-10	103	14	stress	stress	NOUN
gsrj-10	103	15	increase	increase	NOUN
gsrj-10	103	16	da	da	PROPN
gsrj-10	103	17	vta	vta	PROPN
gsrj-10	103	18	release	release	NOUN
gsrj-10	103	19	on	on	ADP
gsrj-10	103	20	a	a	DET
gsrj-10	103	21	synaptic	synaptic	ADJ
gsrj-10	103	22	level	level	NOUN
gsrj-10	103	23	.	.	PUNCT
gsrj-10	104	1	by	by	ADP
gsrj-10	104	2	increasing	increase	VERB
gsrj-10	104	3	excitatory	excitatory	ADJ
gsrj-10	104	4	input	input	NOUN
gsrj-10	104	5	on	on	ADP
gsrj-10	104	6	dopaminergic	dopaminergic	ADJ
gsrj-10	104	7	neurons	neuron	NOUN
gsrj-10	104	8	via	via	ADP
gsrj-10	104	9	nmdareceptor	nmdareceptor	NOUN
gsrj-10	104	10	mediated	mediate	VERB
gsrj-10	104	11	ltp	ltp	PROPN
gsrj-10	104	12	and	and	CCONJ
gsrj-10	104	13	decreasing	decrease	VERB
gsrj-10	104	14	inhibitory	inhibitory	ADJ
gsrj-10	104	15	input	input	NOUN
gsrj-10	104	16	on	on	ADP
gsrj-10	104	17	dopaminergic	dopaminergic	ADJ
gsrj-10	104	18	neurons	neuron	NOUN
gsrj-10	104	19	via	via	ADP
gsrj-10	104	20	gabamediated	gabamediate	VERB
gsrj-10	104	21	ltp	ltp	PROPN
gsrj-10	104	22	,	,	PUNCT
gsrj-10	104	23	there	there	PRON
gsrj-10	104	24	is	be	VERB
gsrj-10	104	25	an	an	DET
gsrj-10	104	26	increase	increase	NOUN
gsrj-10	104	27	in	in	ADP
gsrj-10	104	28	excitatory	excitatory	ADJ
gsrj-10	104	29	postsynaptic	postsynaptic	ADJ
gsrj-10	104	30	potentials	potential	NOUN
gsrj-10	104	31	(	(	PUNCT
gsrj-10	104	32	epsp	epsp	NOUN
gsrj-10	104	33	)	)	PUNCT
gsrj-10	104	34	on	on	ADP
gsrj-10	104	35	the	the	DET
gsrj-10	104	36	dopaminergic	dopaminergic	ADJ
gsrj-10	104	37	neurons	neuron	NOUN
gsrj-10	104	38	,	,	PUNCT
gsrj-10	104	39	leading	lead	VERB
gsrj-10	104	40	to	to	ADP
gsrj-10	104	41	enhanced	enhanced	ADJ
gsrj-10	104	42	dopamine	dopamine	NOUN
gsrj-10	104	43	firing	firing	NOUN
gsrj-10	104	44	.	.	PUNCT
gsrj-10	105	1	with	with	ADP
gsrj-10	105	2	greater	great	ADJ
gsrj-10	105	3	da	da	ADJ
gsrj-10	105	4	firing	firing	NOUN
gsrj-10	105	5	,	,	PUNCT
gsrj-10	105	6	the	the	DET
gsrj-10	105	7	reward	reward	NOUN
gsrj-10	105	8	association	association	NOUN
gsrj-10	105	9	increases	increase	VERB
gsrj-10	105	10	as	as	SCONJ
gsrj-10	105	11	the	the	DET
gsrj-10	105	12	mesolimbic	mesolimbic	ADJ
gsrj-10	105	13	pathway	pathway	NOUN
gsrj-10	105	14	of	of	ADP
gsrj-10	105	15	reward	reward	NOUN
gsrj-10	105	16	is	be	AUX
gsrj-10	105	17	more	more	ADV
gsrj-10	105	18	active	active	ADJ
gsrj-10	105	19	.	.	PUNCT
gsrj-10	106	1	since	since	SCONJ
gsrj-10	106	2	nicotine	nicotine	NOUN
gsrj-10	106	3	and	and	CCONJ
gsrj-10	106	4	stress	stress	NOUN
gsrj-10	106	5	have	have	VERB
gsrj-10	106	6	similar	similar	ADJ
gsrj-10	106	7	results	result	NOUN
gsrj-10	106	8	on	on	ADP
gsrj-10	106	9	da	da	PROPN
gsrj-10	106	10	vta	vta	PROPN
gsrj-10	106	11	firing	fire	VERB
gsrj-10	106	12	via	via	ADP
gsrj-10	106	13	different	different	ADJ
gsrj-10	106	14	pathways	pathway	NOUN
gsrj-10	106	15	involving	involve	VERB
gsrj-10	106	16	nachrs	nachrs	ADJ
gsrj-10	106	17	and	and	CCONJ
gsrj-10	106	18	grs	grs	NUM
gsrj-10	106	19	,	,	PUNCT
gsrj-10	106	20	respectively	respectively	ADV
gsrj-10	106	21	,	,	PUNCT
gsrj-10	106	22	showing	show	VERB
gsrj-10	106	23	that	that	SCONJ
gsrj-10	106	24	nicotine	nicotine	NOUN
gsrj-10	106	25	and	and	CCONJ
gsrj-10	106	26	stress	stress	NOUN
gsrj-10	106	27	exacerbate	exacerbate	VERB
gsrj-10	106	28	each	each	DET
gsrj-10	106	29	other	other	ADJ
gsrj-10	106	30	.	.	PUNCT
gsrj-10	107	1	with	with	ADP
gsrj-10	107	2	nicotine	nicotine	NOUN
gsrj-10	107	3	and	and	CCONJ
gsrj-10	107	4	stress	stress	NOUN
gsrj-10	107	5	’s	’s	PART
gsrj-10	107	6	underlying	underlie	VERB
gsrj-10	107	7	ltp	ltp	NOUN
gsrj-10	107	8	mechanisms	mechanism	NOUN
gsrj-10	107	9	,	,	PUNCT
gsrj-10	107	10	which	which	PRON
gsrj-10	107	11	modulate	modulate	VERB
gsrj-10	107	12	the	the	DET
gsrj-10	107	13	firing	firing	NOUN
gsrj-10	107	14	rates	rate	NOUN
gsrj-10	107	15	of	of	ADP
gsrj-10	107	16	da	da	PROPN
gsrj-10	107	17	vta	vta	PROPN
gsrj-10	107	18	neurons	neuron	NOUN
gsrj-10	107	19	,	,	PUNCT
gsrj-10	107	20	long	long	ADJ
gsrj-10	107	21	-	-	PUNCT
gsrj-10	107	22	term	term	NOUN
gsrj-10	107	23	nicotine	nicotine	NOUN
gsrj-10	107	24	use	use	NOUN
gsrj-10	107	25	and	and	CCONJ
gsrj-10	107	26	stress	stress	NOUN
gsrj-10	107	27	can	can	AUX
gsrj-10	107	28	both	both	PRON
gsrj-10	107	29	have	have	VERB
gsrj-10	107	30	detrimental	detrimental	ADJ
gsrj-10	107	31	effects	effect	NOUN
gsrj-10	107	32	on	on	ADP
gsrj-10	107	33	the	the	DET
gsrj-10	107	34	excitation	excitation	NOUN
gsrj-10	107	35	of	of	ADP
gsrj-10	107	36	da	da	ADJ
gsrj-10	107	37	neurons	neuron	NOUN
gsrj-10	107	38	and	and	CCONJ
gsrj-10	107	39	transmitter	transmitter	NOUN
gsrj-10	107	40	release	release	NOUN
gsrj-10	107	41	;	;	PUNCT
gsrj-10	107	42	in	in	ADP
gsrj-10	107	43	this	this	DET
gsrj-10	107	44	way	way	NOUN
gsrj-10	107	45	,	,	PUNCT
gsrj-10	107	46	increased	increase	VERB
gsrj-10	107	47	77	77	NUM
gsrj-10	107	48	georgetown	georgetown	PROPN
gsrj-10	107	49	scientific	scientific	PROPN
gsrj-10	107	50	research	research	PROPN
gsrj-10	107	51	journal	journal	PROPN
gsrj-10	107	52	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	107	53	dopamine	dopamine	NOUN
gsrj-10	107	54	signaling	signal	VERB
gsrj-10	107	55	underlies	underlie	VERB
gsrj-10	107	56	the	the	DET
gsrj-10	107	57	neural	neural	ADJ
gsrj-10	107	58	mechanism	mechanism	NOUN
gsrj-10	107	59	for	for	ADP
gsrj-10	107	60	addiction	addiction	NOUN
gsrj-10	107	61	.	.	PUNCT
gsrj-10	108	1	furthermore	furthermore	ADV
gsrj-10	108	2	,	,	PUNCT
gsrj-10	108	3	with	with	ADP
gsrj-10	108	4	ltp	ltp	PROPN
gsrj-10	108	5	changing	change	VERB
gsrj-10	108	6	neural	neural	ADJ
gsrj-10	108	7	connections	connection	NOUN
gsrj-10	108	8	,	,	PUNCT
gsrj-10	108	9	this	this	PRON
gsrj-10	108	10	can	can	AUX
gsrj-10	108	11	lead	lead	VERB
gsrj-10	108	12	to	to	ADP
gsrj-10	108	13	effects	effect	NOUN
gsrj-10	108	14	such	such	ADJ
gsrj-10	108	15	as	as	ADP
gsrj-10	108	16	depression	depression	NOUN
gsrj-10	108	17	during	during	ADP
gsrj-10	108	18	withdrawal	withdrawal	NOUN
gsrj-10	108	19	of	of	ADP
gsrj-10	108	20	nicotine	nicotine	NOUN
gsrj-10	108	21	due	due	ADP
gsrj-10	108	22	to	to	ADP
gsrj-10	108	23	not	not	PART
gsrj-10	108	24	enough	enough	ADJ
gsrj-10	108	25	stimulation	stimulation	NOUN
gsrj-10	108	26	of	of	ADP
gsrj-10	108	27	dopamine	dopamine	NOUN
gsrj-10	108	28	pathways	pathway	NOUN
gsrj-10	108	29	in	in	ADP
gsrj-10	108	30	the	the	DET
gsrj-10	108	31	brain	brain	NOUN
gsrj-10	108	32	.	.	PUNCT
gsrj-10	109	1	4	4	X
gsrj-10	109	2	.	.	X
gsrj-10	109	3	future	future	ADJ
gsrj-10	109	4	directions	direction	NOUN
gsrj-10	109	5	:	:	PUNCT
gsrj-10	109	6	decreasing	decrease	VERB
gsrj-10	109	7	dopamine	dopamine	NOUN
gsrj-10	109	8	firing	firing	NOUN
gsrj-10	109	9	as	as	ADP
gsrj-10	109	10	a	a	DET
gsrj-10	109	11	potential	potential	ADJ
gsrj-10	109	12	therapy	therapy	NOUN
gsrj-10	109	13	morel	morel	NOUN
gsrj-10	109	14	et	et	PROPN
gsrj-10	109	15	al	al	PROPN
gsrj-10	109	16	.	.	PROPN
gsrj-10	109	17	2018	2018	NUM
gsrj-10	109	18	demonstrate	demonstrate	VERB
gsrj-10	109	19	that	that	SCONJ
gsrj-10	109	20	social	social	ADJ
gsrj-10	109	21	defeat	defeat	NOUN
gsrj-10	109	22	triggers	trigger	VERB
gsrj-10	109	23	increases	increase	NOUN
gsrj-10	109	24	in	in	ADP
gsrj-10	109	25	vta	vta	PROPN
gsrj-10	109	26	da	da	PROPN
gsrj-10	109	27	neuron	neuron	PROPN
gsrj-10	109	28	spontaneous	spontaneous	ADJ
gsrj-10	109	29	activity	activity	NOUN
gsrj-10	109	30	.	.	PUNCT
gsrj-10	110	1	this	this	PRON
gsrj-10	110	2	is	be	AUX
gsrj-10	110	3	exacerbated	exacerbate	VERB
gsrj-10	110	4	by	by	ADP
gsrj-10	110	5	nicotinic	nicotinic	ADJ
gsrj-10	110	6	binding	binding	NOUN
gsrj-10	110	7	to	to	ADP
gsrj-10	110	8	the	the	DET
gsrj-10	110	9	𝛼𝛼7	𝛼𝛼7	NOUN
gsrj-10	110	10	nachr	nachr	PROPN
gsrj-10	110	11	in	in	ADP
gsrj-10	110	12	the	the	DET
gsrj-10	110	13	vta	vta	PROPN
gsrj-10	110	14	.	.	PUNCT
gsrj-10	111	1	both	both	CCONJ
gsrj-10	111	2	the	the	DET
gsrj-10	111	3	frequency	frequency	NOUN
gsrj-10	111	4	and	and	CCONJ
gsrj-10	111	5	burst	burst	ADJ
gsrj-10	111	6	activity	activity	NOUN
gsrj-10	111	7	increases	increase	NOUN
gsrj-10	111	8	significantly	significantly	ADV
gsrj-10	111	9	in	in	ADP
gsrj-10	111	10	mice	mouse	NOUN
gsrj-10	111	11	exposed	expose	VERB
gsrj-10	111	12	to	to	ADP
gsrj-10	111	13	sd	sd	NOUN
gsrj-10	111	14	and	and	CCONJ
gsrj-10	111	15	nicotine	nicotine	NOUN
gsrj-10	111	16	.	.	PUNCT
gsrj-10	112	1	this	this	DET
gsrj-10	112	2	novel	novel	NOUN
gsrj-10	112	3	finding	finding	NOUN
gsrj-10	112	4	demonstrates	demonstrate	VERB
gsrj-10	112	5	that	that	SCONJ
gsrj-10	112	6	local	local	ADJ
gsrj-10	112	7	vta	vta	PROPN
gsrj-10	112	8	exposure	exposure	NOUN
gsrj-10	112	9	to	to	PART
gsrj-10	112	10	nicotine	nicotine	VERB
gsrj-10	112	11	and	and	CCONJ
gsrj-10	112	12	subsd	subsd	NOUN
gsrj-10	112	13	is	be	AUX
gsrj-10	112	14	sufficient	sufficient	ADJ
gsrj-10	112	15	to	to	PART
gsrj-10	112	16	trigger	trigger	VERB
gsrj-10	112	17	social	social	ADJ
gsrj-10	112	18	aversion	aversion	NOUN
gsrj-10	112	19	.	.	PUNCT
gsrj-10	113	1	given	give	VERB
gsrj-10	113	2	that	that	DET
gsrj-10	113	3	activation	activation	NOUN
gsrj-10	113	4	of	of	ADP
gsrj-10	113	5	nachrs	nachrs	ADJ
gsrj-10	113	6	has	have	VERB
gsrj-10	113	7	an	an	DET
gsrj-10	113	8	effect	effect	NOUN
gsrj-10	113	9	on	on	ADP
gsrj-10	113	10	da	da	PROPN
gsrj-10	113	11	vta	vta	PROPN
gsrj-10	113	12	signaling	signal	VERB
gsrj-10	113	13	,	,	PUNCT
gsrj-10	113	14	da	da	ADJ
gsrj-10	113	15	signaling	signaling	NOUN
gsrj-10	113	16	is	be	AUX
gsrj-10	113	17	implicated	implicate	VERB
gsrj-10	113	18	.	.	PUNCT
gsrj-10	114	1	altogether	altogether	ADV
gsrj-10	114	2	,	,	PUNCT
gsrj-10	114	3	this	this	DET
gsrj-10	114	4	data	data	NOUN
gsrj-10	114	5	suggests	suggest	VERB
gsrj-10	114	6	that	that	SCONJ
gsrj-10	114	7	dopamine	dopamine	NOUN
gsrj-10	114	8	signaling	signal	VERB
gsrj-10	114	9	is	be	AUX
gsrj-10	114	10	necessary	necessary	ADJ
gsrj-10	114	11	for	for	ADP
gsrj-10	114	12	the	the	DET
gsrj-10	114	13	behavioral	behavioral	ADJ
gsrj-10	114	14	manifestations	manifestation	NOUN
gsrj-10	114	15	of	of	ADP
gsrj-10	114	16	social	social	ADJ
gsrj-10	114	17	stress	stress	NOUN
gsrj-10	114	18	.	.	PUNCT
gsrj-10	115	1	preventing	prevent	VERB
gsrj-10	115	2	this	this	DET
gsrj-10	115	3	increased	increase	VERB
gsrj-10	115	4	dopamine	dopamine	NOUN
gsrj-10	115	5	firing	fire	VERB
gsrj-10	115	6	could	could	AUX
gsrj-10	115	7	,	,	PUNCT
gsrj-10	115	8	therefore	therefore	ADV
gsrj-10	115	9	,	,	PUNCT
gsrj-10	115	10	be	be	AUX
gsrj-10	115	11	a	a	DET
gsrj-10	115	12	potential	potential	ADJ
gsrj-10	115	13	therapy	therapy	NOUN
gsrj-10	115	14	for	for	ADP
gsrj-10	115	15	social	social	ADJ
gsrj-10	115	16	aversion	aversion	NOUN
gsrj-10	115	17	,	,	PUNCT
gsrj-10	115	18	which	which	PRON
gsrj-10	115	19	has	have	AUX
gsrj-10	115	20	been	be	AUX
gsrj-10	115	21	established	establish	VERB
gsrj-10	115	22	to	to	PART
gsrj-10	115	23	be	be	AUX
gsrj-10	115	24	a	a	DET
gsrj-10	115	25	symptom	symptom	NOUN
gsrj-10	115	26	in	in	ADP
gsrj-10	115	27	depression	depression	NOUN
gsrj-10	115	28	.	.	PUNCT
gsrj-10	116	1	to	to	PART
gsrj-10	116	2	test	test	VERB
gsrj-10	116	3	how	how	SCONJ
gsrj-10	116	4	dopamine	dopamine	NOUN
gsrj-10	116	5	modulation	modulation	NOUN
gsrj-10	116	6	directly	directly	ADV
gsrj-10	116	7	impacts	impact	VERB
gsrj-10	116	8	the	the	DET
gsrj-10	116	9	vta	vta	PROPN
gsrj-10	116	10	,	,	PUNCT
gsrj-10	116	11	chaudhury	chaudhury	PROPN
gsrj-10	116	12	,	,	PUNCT
gsrj-10	116	13	et	et	PROPN
gsrj-10	116	14	al	al	PROPN
gsrj-10	116	15	.	.	PROPN
gsrj-10	116	16	2013	2013	NUM
gsrj-10	116	17	selectively	selectively	ADV
gsrj-10	116	18	altered	alter	VERB
gsrj-10	116	19	levels	level	NOUN
gsrj-10	116	20	of	of	ADP
gsrj-10	116	21	dopamine	dopamine	NOUN
gsrj-10	116	22	in	in	ADP
gsrj-10	116	23	the	the	DET
gsrj-10	116	24	vta	vta	NOUN
gsrj-10	116	25	using	use	VERB
gsrj-10	116	26	optogenetics	optogenetic	NOUN
gsrj-10	116	27	to	to	PART
gsrj-10	116	28	test	test	VERB
gsrj-10	116	29	social	social	ADJ
gsrj-10	116	30	avoidance	avoidance	NOUN
gsrj-10	116	31	in	in	ADP
gsrj-10	116	32	order	order	NOUN
gsrj-10	116	33	to	to	PART
gsrj-10	116	34	evaluate	evaluate	VERB
gsrj-10	116	35	depression	depression	NOUN
gsrj-10	116	36	-	-	PUNCT
gsrj-10	116	37	like	like	ADJ
gsrj-10	116	38	symptoms	symptom	NOUN
gsrj-10	116	39	in	in	ADP
gsrj-10	116	40	mice.25	mice.25	NOUN
gsrj-10	116	41	while	while	SCONJ
gsrj-10	116	42	morel	morel	PROPN
gsrj-10	116	43	et	et	PROPN
gsrj-10	116	44	al	al	PROPN
gsrj-10	116	45	.	.	PROPN
gsrj-10	116	46	found	find	VERB
gsrj-10	116	47	that	that	SCONJ
gsrj-10	116	48	nicotinic	nicotinic	ADJ
gsrj-10	116	49	binding	binding	NOUN
gsrj-10	116	50	leads	lead	NOUN
gsrj-10	116	51	to	to	ADP
gsrj-10	116	52	alterations	alteration	NOUN
gsrj-10	116	53	in	in	ADP
gsrj-10	116	54	da	da	ADJ
gsrj-10	116	55	signaling	signal	VERB
gsrj-10	116	56	,	,	PUNCT
gsrj-10	116	57	it	it	PRON
gsrj-10	116	58	did	do	AUX
gsrj-10	116	59	not	not	PART
gsrj-10	116	60	directly	directly	ADV
gsrj-10	116	61	establish	establish	VERB
gsrj-10	116	62	that	that	SCONJ
gsrj-10	116	63	modifying	modify	VERB
gsrj-10	116	64	da	da	NOUN
gsrj-10	116	65	signaling	signal	VERB
gsrj-10	116	66	changes	change	NOUN
gsrj-10	116	67	social	social	ADJ
gsrj-10	116	68	aversion	aversion	NOUN
gsrj-10	116	69	-	-	PUNCT
gsrj-10	116	70	like	like	ADJ
gsrj-10	116	71	symptoms	symptom	NOUN
gsrj-10	116	72	.	.	PUNCT
gsrj-10	117	1	this	this	PRON
gsrj-10	117	2	is	be	AUX
gsrj-10	117	3	why	why	SCONJ
gsrj-10	117	4	optogenetic	optogenetic	ADJ
gsrj-10	117	5	inhibition	inhibition	NOUN
gsrj-10	117	6	of	of	ADP
gsrj-10	117	7	dopamine	dopamine	NOUN
gsrj-10	117	8	in	in	ADP
gsrj-10	117	9	the	the	DET
gsrj-10	117	10	vta	vta	NOUN
gsrj-10	117	11	is	be	AUX
gsrj-10	117	12	a	a	DET
gsrj-10	117	13	powerful	powerful	ADJ
gsrj-10	117	14	tool	tool	NOUN
gsrj-10	117	15	to	to	PART
gsrj-10	117	16	investigate	investigate	VERB
gsrj-10	117	17	the	the	DET
gsrj-10	117	18	potential	potential	ADJ
gsrj-10	117	19	therapeutic	therapeutic	ADJ
gsrj-10	117	20	opportunities	opportunity	NOUN
gsrj-10	117	21	for	for	ADP
gsrj-10	117	22	altering	alter	VERB
gsrj-10	117	23	dopamine	dopamine	NOUN
gsrj-10	117	24	signaling	signal	VERB
gsrj-10	117	25	.	.	PUNCT
gsrj-10	118	1	induction	induction	NOUN
gsrj-10	118	2	of	of	ADP
gsrj-10	118	3	phasic	phasic	NOUN
gsrj-10	118	4	firing	fire	VERB
gsrj-10	118	5	in	in	ADP
gsrj-10	118	6	vta	vta	PROPN
gsrj-10	118	7	neurons	neuron	NOUN
gsrj-10	118	8	in	in	ADP
gsrj-10	118	9	the	the	DET
gsrj-10	118	10	vta	vta	PROPN
gsrj-10	118	11	-	-	PUNCT
gsrj-10	118	12	nac	nac	PROPN
gsrj-10	118	13	pathway	pathway	NOUN
gsrj-10	118	14	in	in	ADP
gsrj-10	118	15	mice	mouse	NOUN
gsrj-10	118	16	that	that	PRON
gsrj-10	118	17	were	be	AUX
gsrj-10	118	18	undergoing	undergo	VERB
gsrj-10	118	19	sd	sd	NOUN
gsrj-10	118	20	induced	induce	VERB
gsrj-10	118	21	a	a	DET
gsrj-10	118	22	susceptible	susceptible	ADJ
gsrj-10	118	23	depressive	depressive	ADJ
gsrj-10	118	24	phenotype	phenotype	NOUN
gsrj-10	118	25	with	with	ADP
gsrj-10	118	26	increased	increase	VERB
gsrj-10	118	27	social	social	ADJ
gsrj-10	118	28	avoidance	avoidance	NOUN
gsrj-10	118	29	.	.	PUNCT
gsrj-10	119	1	mice	mouse	NOUN
gsrj-10	119	2	that	that	PRON
gsrj-10	119	3	were	be	AUX
gsrj-10	119	4	resistant	resistant	ADJ
gsrj-10	119	5	to	to	ADP
gsrj-10	119	6	social	social	ADJ
gsrj-10	119	7	avoidance	avoidance	NOUN
gsrj-10	119	8	,	,	PUNCT
gsrj-10	119	9	after	after	ADP
gsrj-10	119	10	being	be	AUX
gsrj-10	119	11	exposed	expose	VERB
gsrj-10	119	12	to	to	ADP
gsrj-10	119	13	sd	sd	NOUN
gsrj-10	119	14	,	,	PUNCT
gsrj-10	119	15	became	become	VERB
gsrj-10	119	16	depressed	depressed	ADJ
gsrj-10	119	17	when	when	SCONJ
gsrj-10	119	18	da	da	NOUN
gsrj-10	119	19	phasic	phasic	NOUN
gsrj-10	119	20	firing	firing	NOUN
gsrj-10	119	21	was	be	AUX
gsrj-10	119	22	optogenetically	optogenetically	ADV
gsrj-10	119	23	induced	induce	VERB
gsrj-10	119	24	.	.	PUNCT
gsrj-10	120	1	stimulation	stimulation	NOUN
gsrj-10	120	2	of	of	ADP
gsrj-10	120	3	phasic	phasic	ADJ
gsrj-10	120	4	dopamine	dopamine	NOUN
gsrj-10	120	5	firing	firing	NOUN
gsrj-10	120	6	corresponded	correspond	VERB
gsrj-10	120	7	to	to	ADP
gsrj-10	120	8	a	a	DET
gsrj-10	120	9	rapid	rapid	ADJ
gsrj-10	120	10	onset	onset	NOUN
gsrj-10	120	11	of	of	ADP
gsrj-10	120	12	the	the	DET
gsrj-10	120	13	susceptible	susceptible	ADJ
gsrj-10	120	14	phenotype	phenotype	NOUN
gsrj-10	120	15	after	after	ADP
gsrj-10	120	16	stress	stress	NOUN
gsrj-10	120	17	exposure	exposure	NOUN
gsrj-10	120	18	.	.	PUNCT
gsrj-10	121	1	the	the	DET
gsrj-10	121	2	fact	fact	NOUN
gsrj-10	121	3	that	that	SCONJ
gsrj-10	121	4	social	social	ADJ
gsrj-10	121	5	stress	stress	NOUN
gsrj-10	121	6	was	be	AUX
gsrj-10	121	7	a	a	DET
gsrj-10	121	8	precursor	precursor	NOUN
gsrj-10	121	9	to	to	ADP
gsrj-10	121	10	dopamine	dopamine	NOUN
gsrj-10	121	11	alteration	alteration	NOUN
gsrj-10	121	12	in	in	ADP
gsrj-10	121	13	rendering	render	VERB
gsrj-10	121	14	a	a	DET
gsrj-10	121	15	depressed	depressed	ADJ
gsrj-10	121	16	phenotype	phenotype	NOUN
gsrj-10	121	17	shows	show	VERB
gsrj-10	121	18	the	the	DET
gsrj-10	121	19	context	context	NOUN
gsrj-10	121	20	-	-	PUNCT
gsrj-10	121	21	dependent	dependent	ADJ
gsrj-10	121	22	alterations	alteration	NOUN
gsrj-10	121	23	that	that	PRON
gsrj-10	121	24	occur	occur	VERB
gsrj-10	121	25	.	.	PUNCT
gsrj-10	122	1	this	this	DET
gsrj-10	122	2	finding	finding	NOUN
gsrj-10	122	3	emphasizes	emphasize	VERB
gsrj-10	122	4	that	that	SCONJ
gsrj-10	122	5	dopamine	dopamine	NOUN
gsrj-10	122	6	is	be	AUX
gsrj-10	122	7	being	be	AUX
gsrj-10	122	8	directly	directly	ADV
gsrj-10	122	9	acted	act	VERB
gsrj-10	122	10	on	on	ADP
gsrj-10	122	11	,	,	PUNCT
gsrj-10	122	12	which	which	PRON
gsrj-10	122	13	confirms	confirm	VERB
gsrj-10	122	14	that	that	SCONJ
gsrj-10	122	15	vta	vta	PROPN
gsrj-10	122	16	da	da	PROPN
gsrj-10	122	17	neurons	neuron	NOUN
gsrj-10	122	18	serve	serve	VERB
gsrj-10	122	19	in	in	ADP
gsrj-10	122	20	stressresponse	stressresponse	NOUN
gsrj-10	122	21	modulation	modulation	NOUN
gsrj-10	122	22	,	,	PUNCT
gsrj-10	122	23	contributing	contribute	VERB
gsrj-10	122	24	to	to	ADP
gsrj-10	122	25	a	a	DET
gsrj-10	122	26	depressivelike	depressivelike	ADJ
gsrj-10	122	27	phenotype	phenotype	NOUN
gsrj-10	122	28	.	.	PUNCT
gsrj-10	123	1	deep	deep	ADJ
gsrj-10	123	2	brain	brain	NOUN
gsrj-10	123	3	stimulation	stimulation	NOUN
gsrj-10	123	4	(	(	PUNCT
gsrj-10	123	5	dbs	dbs	PROPN
gsrj-10	123	6	)	)	PUNCT
gsrj-10	123	7	therapies	therapy	NOUN
gsrj-10	123	8	to	to	ADP
gsrj-10	123	9	the	the	DET
gsrj-10	123	10	vta	vta	PROPN
gsrj-10	123	11	could	could	AUX
gsrj-10	123	12	be	be	AUX
gsrj-10	123	13	an	an	DET
gsrj-10	123	14	effective	effective	ADJ
gsrj-10	123	15	way	way	NOUN
gsrj-10	123	16	to	to	PART
gsrj-10	123	17	reduce	reduce	VERB
gsrj-10	123	18	dopamine	dopamine	NOUN
gsrj-10	123	19	firing	firing	NOUN
gsrj-10	123	20	and	and	CCONJ
gsrj-10	123	21	mediate	mediate	VERB
gsrj-10	123	22	anti	anti	ADJ
gsrj-10	123	23	-	-	ADJ
gsrj-10	123	24	depressive	depressive	ADJ
gsrj-10	123	25	effects	effect	NOUN
gsrj-10	123	26	.	.	PUNCT
gsrj-10	124	1	the	the	DET
gsrj-10	124	2	circuit	circuit	NOUN
gsrj-10	124	3	and	and	CCONJ
gsrj-10	124	4	context	context	NOUN
gsrj-10	124	5	-	-	PUNCT
gsrj-10	124	6	specific	specific	ADJ
gsrj-10	124	7	nature	nature	NOUN
gsrj-10	124	8	of	of	ADP
gsrj-10	124	9	this	this	DET
gsrj-10	124	10	pathway	pathway	NOUN
gsrj-10	124	11	make	make	VERB
gsrj-10	124	12	it	it	PRON
gsrj-10	124	13	a	a	DET
gsrj-10	124	14	prime	prime	ADJ
gsrj-10	124	15	therapeutic	therapeutic	ADJ
gsrj-10	124	16	target	target	NOUN
gsrj-10	124	17	.	.	PUNCT
gsrj-10	125	1	if	if	SCONJ
gsrj-10	125	2	dopamine	dopamine	NOUN
gsrj-10	125	3	activity	activity	NOUN
gsrj-10	125	4	is	be	AUX
gsrj-10	125	5	restored	restore	VERB
gsrj-10	125	6	to	to	ADP
gsrj-10	125	7	tonic	tonic	NOUN
gsrj-10	125	8	firing	firing	NOUN
gsrj-10	125	9	following	follow	VERB
gsrj-10	125	10	stress	stress	NOUN
gsrj-10	125	11	,	,	PUNCT
gsrj-10	125	12	social	social	ADJ
gsrj-10	125	13	defeat	defeat	NOUN
gsrj-10	125	14	scores	score	NOUN
gsrj-10	125	15	decrease.25	decrease.25	VERB
gsrj-10	125	16	in	in	ADP
gsrj-10	125	17	dbs	dbs	PROPN
gsrj-10	125	18	surgery	surgery	NOUN
gsrj-10	125	19	,	,	PUNCT
gsrj-10	125	20	an	an	DET
gsrj-10	125	21	electrode	electrode	NOUN
gsrj-10	125	22	is	be	AUX
gsrj-10	125	23	stereotactically	stereotactically	ADV
gsrj-10	125	24	implanted	implant	VERB
gsrj-10	125	25	into	into	ADP
gsrj-10	125	26	specific	specific	ADJ
gsrj-10	125	27	neuroanatomical	neuroanatomical	ADJ
gsrj-10	125	28	regions	region	NOUN
gsrj-10	125	29	,	,	PUNCT
gsrj-10	125	30	and	and	CCONJ
gsrj-10	125	31	electrical	electrical	ADJ
gsrj-10	125	32	stimulation	stimulation	NOUN
gsrj-10	125	33	is	be	AUX
gsrj-10	125	34	provided	provide	VERB
gsrj-10	125	35	via	via	ADP
gsrj-10	125	36	a	a	DET
gsrj-10	125	37	pacemaker	pacemaker	NOUN
gsrj-10	125	38	-	-	PUNCT
gsrj-10	125	39	like	like	ADJ
gsrj-10	125	40	stimulator.26	stimulator.26	ADJ
gsrj-10	125	41	dbs	dbs	NOUN
gsrj-10	125	42	is	be	AUX
gsrj-10	125	43	used	use	VERB
gsrj-10	125	44	in	in	ADP
gsrj-10	125	45	movement	movement	NOUN
gsrj-10	125	46	disorders	disorder	NOUN
gsrj-10	125	47	such	such	ADJ
gsrj-10	125	48	as	as	ADP
gsrj-10	125	49	parkinson	parkinson	NOUN
gsrj-10	125	50	’s	’s	PART
gsrj-10	125	51	disease	disease	NOUN
gsrj-10	125	52	.	.	PUNCT
gsrj-10	126	1	recently	recently	ADV
gsrj-10	126	2	,	,	PUNCT
gsrj-10	126	3	dbs	dbs	PROPN
gsrj-10	126	4	has	have	AUX
gsrj-10	126	5	been	be	AUX
gsrj-10	126	6	studied	study	VERB
gsrj-10	126	7	for	for	ADP
gsrj-10	126	8	neuropsychiatric	neuropsychiatric	ADJ
gsrj-10	126	9	disorders	disorder	NOUN
gsrj-10	126	10	.	.	PUNCT
gsrj-10	127	1	open	open	ADJ
gsrj-10	127	2	-	-	PUNCT
gsrj-10	127	3	label	label	NOUN
gsrj-10	127	4	studies	study	NOUN
gsrj-10	127	5	have	have	VERB
gsrj-10	127	6	convincing	convince	VERB
gsrj-10	127	7	data	datum	NOUN
gsrj-10	127	8	that	that	PRON
gsrj-10	127	9	suggest	suggest	VERB
gsrj-10	127	10	that	that	SCONJ
gsrj-10	127	11	dbs	dbs	PROPN
gsrj-10	127	12	is	be	AUX
gsrj-10	127	13	effective	effective	ADJ
gsrj-10	127	14	in	in	ADP
gsrj-10	127	15	mediating	mediate	VERB
gsrj-10	127	16	antidepressant	antidepressant	ADJ
gsrj-10	127	17	effects	effect	NOUN
gsrj-10	127	18	in	in	ADP
gsrj-10	127	19	individuals	individual	NOUN
gsrj-10	127	20	who	who	PRON
gsrj-10	127	21	do	do	AUX
gsrj-10	127	22	not	not	PART
gsrj-10	127	23	respond	respond	VERB
gsrj-10	127	24	to	to	ADP
gsrj-10	127	25	conventional	conventional	ADJ
gsrj-10	127	26	treatments	treatment	NOUN
gsrj-10	127	27	for	for	ADP
gsrj-10	127	28	depression.26	depression.26	NOUN
gsrj-10	127	29	data	datum	NOUN
gsrj-10	127	30	from	from	ADP
gsrj-10	127	31	clinical	clinical	ADJ
gsrj-10	127	32	studies	study	NOUN
gsrj-10	127	33	of	of	ADP
gsrj-10	127	34	the	the	DET
gsrj-10	127	35	neurophysiological	neurophysiological	ADJ
gsrj-10	127	36	effects	effect	NOUN
gsrj-10	127	37	of	of	ADP
gsrj-10	127	38	dbs	dbs	PROPN
gsrj-10	127	39	suggest	suggest	VERB
gsrj-10	127	40	that	that	SCONJ
gsrj-10	127	41	electrical	electrical	ADJ
gsrj-10	127	42	stimulation	stimulation	NOUN
gsrj-10	127	43	leads	lead	VERB
gsrj-10	127	44	to	to	ADP
gsrj-10	127	45	both	both	CCONJ
gsrj-10	127	46	short	short	ADJ
gsrj-10	127	47	-	-	PUNCT
gsrj-10	127	48	term	term	NOUN
gsrj-10	127	49	and	and	CCONJ
gsrj-10	127	50	long	long	ADJ
gsrj-10	127	51	-	-	PUNCT
gsrj-10	127	52	term	term	NOUN
gsrj-10	127	53	effects	effect	NOUN
gsrj-10	127	54	on	on	ADP
gsrj-10	127	55	firing	fire	VERB
gsrj-10	127	56	rates	rate	NOUN
gsrj-10	127	57	and	and	CCONJ
gsrj-10	127	58	patterns	pattern	NOUN
gsrj-10	127	59	.	.	PUNCT
gsrj-10	128	1	although	although	SCONJ
gsrj-10	128	2	the	the	DET
gsrj-10	128	3	direct	direct	ADJ
gsrj-10	128	4	mechanism	mechanism	NOUN
gsrj-10	128	5	of	of	ADP
gsrj-10	128	6	action	action	NOUN
gsrj-10	128	7	by	by	ADP
gsrj-10	128	8	which	which	PRON
gsrj-10	128	9	dbs	dbs	PROPN
gsrj-10	128	10	works	work	VERB
gsrj-10	128	11	is	be	AUX
gsrj-10	128	12	unknown	unknown	ADJ
gsrj-10	128	13	,	,	PUNCT
gsrj-10	128	14	it	it	PRON
gsrj-10	128	15	has	have	AUX
gsrj-10	128	16	been	be	AUX
gsrj-10	128	17	proposed	propose	VERB
gsrj-10	128	18	that	that	SCONJ
gsrj-10	128	19	dbs	dbs	PROPN
gsrj-10	128	20	inhibits	inhibit	VERB
gsrj-10	128	21	neurons	neuron	NOUN
gsrj-10	128	22	being	be	AUX
gsrj-10	128	23	stimulated	stimulate	VERB
gsrj-10	128	24	,	,	PUNCT
gsrj-10	128	25	potentially	potentially	ADV
gsrj-10	128	26	by	by	ADP
gsrj-10	128	27	modulating	modulate	VERB
gsrj-10	128	28	the	the	DET
gsrj-10	128	29	electrical	electrical	ADJ
gsrj-10	128	30	activity	activity	NOUN
gsrj-10	128	31	of	of	ADP
gsrj-10	128	32	potassium	potassium	NOUN
gsrj-10	128	33	and	and	CCONJ
gsrj-10	128	34	sodium	sodium	NOUN
gsrj-10	128	35	channels	channel	NOUN
gsrj-10	128	36	.	.	PUNCT
gsrj-10	129	1	another	another	DET
gsrj-10	129	2	78	78	NUM
gsrj-10	129	3	georgetown	georgetown	PROPN
gsrj-10	129	4	scientific	scientific	ADJ
gsrj-10	129	5	research	research	NOUN
gsrj-10	129	6	journal	journal	NOUN
gsrj-10	129	7	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	129	8	proposed	propose	VERB
gsrj-10	129	9	mechanism	mechanism	NOUN
gsrj-10	129	10	of	of	ADP
gsrj-10	129	11	dbs	dbs	PROPN
gsrj-10	129	12	is	be	AUX
gsrj-10	129	13	that	that	SCONJ
gsrj-10	129	14	it	it	PRON
gsrj-10	129	15	disrupts	disrupt	VERB
gsrj-10	129	16	neuronal	neuronal	ADJ
gsrj-10	129	17	signals	signal	NOUN
gsrj-10	129	18	and	and	CCONJ
gsrj-10	129	19	activity	activity	NOUN
gsrj-10	129	20	from	from	ADP
gsrj-10	129	21	being	be	AUX
gsrj-10	129	22	propagated	propagate	VERB
gsrj-10	129	23	in	in	ADP
gsrj-10	129	24	neural	neural	ADJ
gsrj-10	129	25	pathways	pathway	NOUN
gsrj-10	129	26	.	.	PUNCT
gsrj-10	130	1	recently	recently	ADV
gsrj-10	130	2	,	,	PUNCT
gsrj-10	130	3	a	a	DET
gsrj-10	130	4	review	review	NOUN
gsrj-10	130	5	was	be	AUX
gsrj-10	130	6	published	publish	VERB
gsrj-10	130	7	that	that	PRON
gsrj-10	130	8	investigated	investigate	VERB
gsrj-10	130	9	dbs	dbs	NOUN
gsrj-10	130	10	for	for	ADP
gsrj-10	130	11	treatment	treatment	NOUN
gsrj-10	130	12	-	-	PUNCT
gsrj-10	130	13	resistant	resistant	ADJ
gsrj-10	130	14	depression.27	depression.27	NOUN
gsrj-10	130	15	the	the	DET
gsrj-10	130	16	review	review	NOUN
gsrj-10	130	17	highlights	highlight	VERB
gsrj-10	130	18	clinical	clinical	ADJ
gsrj-10	130	19	trials	trial	NOUN
gsrj-10	130	20	where	where	SCONJ
gsrj-10	130	21	dbs	dbs	PROPN
gsrj-10	130	22	was	be	AUX
gsrj-10	130	23	used	use	VERB
gsrj-10	130	24	to	to	PART
gsrj-10	130	25	treat	treat	VERB
gsrj-10	130	26	depression	depression	NOUN
gsrj-10	130	27	in	in	ADP
gsrj-10	130	28	different	different	ADJ
gsrj-10	130	29	brain	brain	NOUN
gsrj-10	130	30	regions	region	NOUN
gsrj-10	130	31	.	.	PUNCT
gsrj-10	131	1	the	the	DET
gsrj-10	131	2	results	result	NOUN
gsrj-10	131	3	from	from	ADP
gsrj-10	131	4	this	this	DET
gsrj-10	131	5	review	review	NOUN
gsrj-10	131	6	emphasize	emphasize	VERB
gsrj-10	131	7	the	the	DET
gsrj-10	131	8	importance	importance	NOUN
gsrj-10	131	9	of	of	ADP
gsrj-10	131	10	the	the	DET
gsrj-10	131	11	medial	medial	ADJ
gsrj-10	131	12	forebrain	forebrain	NOUN
gsrj-10	131	13	bundle	bundle	NOUN
gsrj-10	131	14	(	(	PUNCT
gsrj-10	131	15	mfb)—a	mfb)—a	NOUN
gsrj-10	131	16	pathway	pathway	NOUN
gsrj-10	131	17	between	between	ADP
gsrj-10	131	18	the	the	DET
gsrj-10	131	19	vta	vta	PROPN
gsrj-10	131	20	and	and	CCONJ
gsrj-10	131	21	lateral	lateral	ADJ
gsrj-10	131	22	hypothalamus	hypothalamus	NOUN
gsrj-10	131	23	—	—	PUNCT
gsrj-10	131	24	as	as	ADP
gsrj-10	131	25	a	a	DET
gsrj-10	131	26	potential	potential	ADJ
gsrj-10	131	27	therapeutic	therapeutic	ADJ
gsrj-10	131	28	target	target	NOUN
gsrj-10	131	29	for	for	ADP
gsrj-10	131	30	dbs	dbs	NOUN
gsrj-10	131	31	in	in	ADP
gsrj-10	131	32	the	the	DET
gsrj-10	131	33	vta	vta	PROPN
gsrj-10	131	34	-	-	PUNCT
gsrj-10	131	35	nac	nac	PROPN
gsrj-10	131	36	pathway	pathway	NOUN
gsrj-10	131	37	(	(	PUNCT
gsrj-10	131	38	figure	figure	NOUN
gsrj-10	131	39	6	6	NUM
gsrj-10	131	40	)	)	PUNCT
gsrj-10	131	41	.	.	PUNCT
gsrj-10	132	1	figure	figure	VERB
gsrj-10	132	2	6	6	NUM
gsrj-10	132	3	.	.	PUNCT
gsrj-10	133	1	the	the	DET
gsrj-10	133	2	medial	medial	ADJ
gsrj-10	133	3	forebrain	forebrain	NOUN
gsrj-10	133	4	bundle	bundle	NOUN
gsrj-10	133	5	(	(	PUNCT
gsrj-10	133	6	mfb	mfb	NOUN
gsrj-10	133	7	)	)	PUNCT
gsrj-10	133	8	connects	connect	VERB
gsrj-10	133	9	the	the	DET
gsrj-10	133	10	vta	vta	PROPN
gsrj-10	133	11	and	and	CCONJ
gsrj-10	133	12	lateral	lateral	ADJ
gsrj-10	133	13	hypothalamus	hypothalamus	PROPN
gsrj-10	133	14	.	.	PUNCT
gsrj-10	134	1	the	the	DET
gsrj-10	134	2	vta	vta	PROPN
gsrj-10	134	3	is	be	AUX
gsrj-10	134	4	connected	connect	VERB
gsrj-10	134	5	to	to	ADP
gsrj-10	134	6	subcortical	subcortical	ADJ
gsrj-10	134	7	and	and	CCONJ
gsrj-10	134	8	cortical	cortical	ADJ
gsrj-10	134	9	prefrontal	prefrontal	ADJ
gsrj-10	134	10	regions	region	NOUN
gsrj-10	134	11	.	.	PUNCT
gsrj-10	135	1	the	the	DET
gsrj-10	135	2	mesolimbic	mesolimbic	ADJ
gsrj-10	135	3	reward	reward	NOUN
gsrj-10	135	4	pathway	pathway	NOUN
gsrj-10	135	5	is	be	AUX
gsrj-10	135	6	contained	contain	VERB
gsrj-10	135	7	within	within	ADP
gsrj-10	135	8	the	the	DET
gsrj-10	135	9	mfb	mfb	NOUN
gsrj-10	135	10	,	,	PUNCT
gsrj-10	135	11	composed	compose	VERB
gsrj-10	135	12	of	of	ADP
gsrj-10	135	13	dopaminergic	dopaminergic	ADJ
gsrj-10	135	14	axons	axon	NOUN
gsrj-10	135	15	that	that	PRON
gsrj-10	135	16	project	project	VERB
gsrj-10	135	17	from	from	ADP
gsrj-10	135	18	the	the	DET
gsrj-10	135	19	vta	vta	PROPN
gsrj-10	135	20	to	to	ADP
gsrj-10	135	21	nac.28	nac.28	PROPN
gsrj-10	135	22	(	(	PUNCT
gsrj-10	135	23	figure	figure	NOUN
gsrj-10	135	24	taken	take	VERB
gsrj-10	135	25	from	from	ADP
gsrj-10	135	26	mcgill	mcgill	PROPN
gsrj-10	135	27	university	university	PROPN
gsrj-10	135	28	)	)	PUNCT
gsrj-10	135	29	�	�	PROPN
gsrj-10	135	30	�	�	PROPN
gsrj-10	135	31	�	�	PROPN
gsrj-10	135	32	�	�	PROPN
gsrj-10	135	33	�	�	PROPN
gsrj-10	135	34	the	the	DET
gsrj-10	135	35	nerve	nerve	NOUN
gsrj-10	135	36	fibers	fiber	NOUN
gsrj-10	135	37	of	of	ADP
gsrj-10	135	38	the	the	DET
gsrj-10	135	39	reward	reward	NOUN
gsrj-10	135	40	circuit	circuit	NOUN
gsrj-10	135	41	are	be	AUX
gsrj-10	135	42	located	locate	VERB
gsrj-10	135	43	in	in	ADP
gsrj-10	135	44	this	this	DET
gsrj-10	135	45	pathway	pathway	NOUN
gsrj-10	135	46	,	,	PUNCT
gsrj-10	135	47	which	which	PRON
gsrj-10	135	48	is	be	AUX
gsrj-10	135	49	composed	compose	VERB
gsrj-10	135	50	of	of	ADP
gsrj-10	135	51	dopaminergic	dopaminergic	ADJ
gsrj-10	135	52	neuron	neuron	NOUN
gsrj-10	135	53	axon	axon	NOUN
gsrj-10	135	54	projections	projection	NOUN
gsrj-10	135	55	that	that	PRON
gsrj-10	135	56	go	go	VERB
gsrj-10	135	57	from	from	ADP
gsrj-10	135	58	the	the	DET
gsrj-10	135	59	vta	vta	PROPN
gsrj-10	135	60	to	to	ADP
gsrj-10	135	61	the	the	DET
gsrj-10	135	62	nac	nac	PROPN
gsrj-10	135	63	.	.	PUNCT
gsrj-10	136	1	even	even	ADV
gsrj-10	136	2	though	though	SCONJ
gsrj-10	136	3	this	this	DET
gsrj-10	136	4	pathway	pathway	NOUN
gsrj-10	136	5	involves	involve	VERB
gsrj-10	136	6	brain	brain	NOUN
gsrj-10	136	7	regions	region	NOUN
gsrj-10	136	8	beyond	beyond	ADP
gsrj-10	136	9	the	the	DET
gsrj-10	136	10	75"	75"	PROPN
gsrj-10	136	11	�	�	PROPN
gsrj-10	136	12	�	�	PROPN
gsrj-10	136	13	�	�	PROPN
gsrj-10	136	14	nac	nac	PROPN
gsrj-10	136	15	connection	connection	NOUN
gsrj-10	136	16	that	that	PRON
gsrj-10	136	17	morel	morel	PROPN
gsrj-10	136	18	et	et	PROPN
gsrj-10	136	19	al	al	PROPN
gsrj-10	136	20	.	.	PROPN
gsrj-10	136	21	focus	focus	VERB
gsrj-10	136	22	on	on	ADP
gsrj-10	136	23	,	,	PUNCT
gsrj-10	136	24	it	it	PRON
gsrj-10	136	25	is	be	AUX
gsrj-10	136	26	useful	useful	ADJ
gsrj-10	136	27	to	to	PART
gsrj-10	136	28	evaluate	evaluate	VERB
gsrj-10	136	29	dbs	dbs	NOUN
gsrj-10	136	30	as	as	ADP
gsrj-10	136	31	a	a	DET
gsrj-10	136	32	potential	potential	ADJ
gsrj-10	136	33	therapy	therapy	NOUN
gsrj-10	136	34	.	.	PUNCT
gsrj-10	137	1	despite	despite	SCONJ
gsrj-10	137	2	being	be	AUX
gsrj-10	137	3	limited	limit	VERB
gsrj-10	137	4	to	to	ADP
gsrj-10	137	5	11	11	NUM
gsrj-10	137	6	patients	patient	NOUN
gsrj-10	137	7	,	,	PUNCT
gsrj-10	137	8	findings	finding	NOUN
gsrj-10	137	9	indicate	indicate	VERB
gsrj-10	137	10	that	that	SCONJ
gsrj-10	137	11	dbs	dbs	NOUN
gsrj-10	137	12	of	of	ADP
gsrj-10	137	13	the	the	DET
gsrj-10	137	14	mfb	mfb	NOUN
gsrj-10	137	15	could	could	AUX
gsrj-10	137	16	induce	induce	VERB
gsrj-10	137	17	antidepressant	antidepressant	ADJ
gsrj-10	137	18	effects	effect	NOUN
gsrj-10	137	19	.	.	PUNCT
gsrj-10	138	1	short	short	ADJ
gsrj-10	138	2	-	-	PUNCT
gsrj-10	138	3	term	term	NOUN
gsrj-10	138	4	bilateral	bilateral	ADJ
gsrj-10	138	5	stimulation	stimulation	NOUN
gsrj-10	138	6	of	of	ADP
gsrj-10	138	7	the	the	DET
gsrj-10	138	8	mfb	mfb	NOUN
gsrj-10	138	9	led	lead	VERB
gsrj-10	138	10	to	to	ADP
gsrj-10	138	11	a	a	DET
gsrj-10	138	12	rapid	rapid	ADJ
gsrj-10	138	13	reduction	reduction	NOUN
gsrj-10	138	14	of	of	ADP
gsrj-10	138	15	depressive	depressive	ADJ
gsrj-10	138	16	symptoms	symptom	NOUN
gsrj-10	138	17	in	in	ADP
gsrj-10	138	18	6	6	NUM
gsrj-10	138	19	out	out	ADP
gsrj-10	138	20	of	of	ADP
gsrj-10	138	21	7	7	NUM
gsrj-10	138	22	patients	patient	NOUN
gsrj-10	138	23	in	in	ADP
gsrj-10	138	24	one	one	NUM
gsrj-10	138	25	study	study	NOUN
gsrj-10	138	26	.	.	PUNCT
gsrj-10	139	1	in	in	ADP
gsrj-10	139	2	other	other	ADJ
gsrj-10	139	3	studies	study	NOUN
gsrj-10	139	4	,	,	PUNCT
gsrj-10	139	5	the	the	DET
gsrj-10	139	6	antidepressant	antidepressant	ADJ
gsrj-10	139	7	effects	effect	NOUN
gsrj-10	139	8	were	be	AUX
gsrj-10	139	9	also	also	ADV
gsrj-10	139	10	consistent	consistent	ADJ
gsrj-10	139	11	,	,	PUNCT
gsrj-10	139	12	with	with	ADP
gsrj-10	139	13	no	no	DET
gsrj-10	139	14	evidence	evidence	NOUN
gsrj-10	139	15	of	of	ADP
gsrj-10	139	16	cognitive	cognitive	ADJ
gsrj-10	139	17	impairment	impairment	NOUN
gsrj-10	139	18	following	follow	VERB
gsrj-10	139	19	months	month	NOUN
gsrj-10	139	20	of	of	ADP
gsrj-10	139	21	stimulation	stimulation	NOUN
gsrj-10	139	22	.	.	PUNCT
gsrj-10	140	1	5if	5if	ADJ
gsrj-10	140	2	�	�	PROPN
gsrj-10	140	3	izqpuiftj[fe	izqpuiftj[fe	PROPN
gsrj-10	140	4	�	�	PROPN
gsrj-10	140	5	nfdibojtn	nfdibojtn	PROPN
gsrj-10	140	6	�	�	PROPN
gsrj-10	140	7	pg	pg	PROPN
gsrj-10	140	8	�	�	PROPN
gsrj-10	140	9	bdujpo	bdujpo	PROPN
gsrj-10	140	10	�	�	PROPN
gsrj-10	140	11	gps	gps	PROPN
gsrj-10	140	12	�	�	PROPN
gsrj-10	140	13	uiftf	uiftf	PROPN
gsrj-10	140	14	�	�	PROPN
gsrj-10	140	15	fodpvsbhjoh	fodpvsbhjoh	PROPN
gsrj-10	140	16	�	�	PROPN
gsrj-10	140	17	sftvmut	sftvmut	PROPN
gsrj-10	140	18	�	�	PROPN
gsrj-10	140	19	jt	jt	PROPN
gsrj-10	140	20	�	�	PROPN
gsrj-10	140	21	uibu	uibu	PROPN
gsrj-10	140	22	�	�	PROPN
gsrj-10	140	23	%	%	NOUN
gsrj-10	140	24	#	#	SYM
gsrj-10	140	25	4	4	NUM
gsrj-10	140	26	�	�	PROPN
gsrj-10	140	27	bdujwbuft	bdujwbuft	PROPN
gsrj-10	140	28	�	�	PROPN
gsrj-10	140	29	uif	uif	PROPN
gsrj-10	140	30	�	�	PROPN
gsrj-10	140	31	nftpdpsujdpmjncjd	nftpdpsujdpmjncjd	PROPN
gsrj-10	140	32	�	�	PROPN
gsrj-10	140	33	�	�	PROPN
gsrj-10	140	34	cz	cz	PROPN
gsrj-10	140	35	�	�	PROPN
gsrj-10	140	36	npevmbujoh	npevmbujoh	PROPN
gsrj-10	140	37	�	�	PROPN
gsrj-10	140	38	tztufn	tztufn	PROPN
gsrj-10	140	39	�	�	PROPN
gsrj-10	140	40	epqbnjofshjd	epqbnjofshjd	PROPN
gsrj-10	140	41	�	�	PROPN
gsrj-10	140	42	�	�	PROPN
gsrj-10	140	43	hmvubnbufshjd	hmvubnbufshjd	PROPN
gsrj-10	140	44	�	�	PROPN
gsrj-10	140	45	boe	boe	PROPN
gsrj-10	140	46	�	�	PROPN
gsrj-10	140	47	ofvspusbotnjttjpo	ofvspusbotnjttjpo	PROPN
gsrj-10	140	48	�	�	PROPN
gsrj-10	140	49	�	�	PROPN
gsrj-10	140	50	5if	5if	ADJ
gsrj-10	140	51	�	�	PROPN
gsrj-10	140	52	djsdvju	djsdvju	PROPN
gsrj-10	140	53	�	�	PROPN
gsrj-10	140	54	uibu	uibu	ADJ
gsrj-10	140	55	�	�	PROPN
gsrj-10	140	56	bdijfwft	bdijfwft	NOUN
gsrj-10	140	57	�	�	PROPN
gsrj-10	140	58	uijt	uijt	PROPN
gsrj-10	140	59	�	�	PROPN
gsrj-10	140	60	ofvspusbotnjttjpo	ofvspusbotnjttjpo	PROPN
gsrj-10	140	61	�	�	PROPN
gsrj-10	140	62	nbz	nbz	PROPN
gsrj-10	140	63	�	�	PROPN
gsrj-10	140	64	cf	cf	NOUN
gsrj-10	140	65	�	�	PROPN
gsrj-10	140	66	uibu	uibu	ADJ
gsrj-10	140	67	�	�	PROPN
gsrj-10	140	68	%#4	%#4	NOUN
gsrj-10	140	69	�	�	PROPN
gsrj-10	140	70	bmufst	bmufst	PROPN
gsrj-10	140	71	�	�	PROPN
gsrj-10	140	72	uif	uif	PROPN
gsrj-10	140	73	�	�	PROPN
gsrj-10	140	74	gjsjoh	gjsjoh	PROPN
gsrj-10	140	75	�	�	PROPN
gsrj-10	140	76	pg	pg	PROPN
gsrj-10	140	77	�	�	PROPN
gsrj-10	140	78	hmvubnbufshjd	hmvubnbufshjd	PROPN
gsrj-10	140	79	�	�	PROPN
gsrj-10	140	80	gjcfst	gjcfst	PROPN
gsrj-10	140	81	�	�	PROPN
gsrj-10	140	82	gspn	gspn	PROPN
gsrj-10	140	83	�	�	PROPN
gsrj-10	140	84	uif	uif	PROPN
gsrj-10	140	85	�	�	PROPN
gsrj-10	140	86	n1'$	n1'$	NOUN
gsrj-10	140	87	�	�	PROPN
gsrj-10	140	88	up	up	ADP
gsrj-10	140	89	�	�	PROPN
gsrj-10	140	90	uif	uif	PROPN
gsrj-10	140	91	�	�	PROPN
gsrj-10	140	92	75	75	NUM
gsrj-10	140	93	"	"	PUNCT
gsrj-10	140	94	�	�	PROPN
gsrj-10	140	95	xijdi	xijdi	PROPN
gsrj-10	140	96	�	�	PROPN
gsrj-10	140	97	joejsfdumz	joejsfdumz	PROPN
gsrj-10	140	98	�	�	PROPN
gsrj-10	140	99	npevmbuft	npevmbuft	PROPN
gsrj-10	140	100	�	�	PROPN
gsrj-10	140	101	epqbnjofshjd	epqbnjofshjd	PROPN
gsrj-10	140	102	�	�	PROPN
gsrj-10	140	103	gjsjoh	gjsjoh	PROPN
gsrj-10	140	104	�	�	PROPN
gsrj-10	140	105	bu	bu	PROPN
gsrj-10	140	106	�	�	PROPN
gsrj-10	140	107	uif	uif	PROPN
gsrj-10	140	108	�	�	PROPN
gsrj-10	140	109	75	75	NUM
gsrj-10	140	110	"	"	PUNCT
gsrj-10	140	111	�	�	PROPN
gsrj-10	140	112	�	�	PROPN
gsrj-10	140	113	&	&	CCONJ
gsrj-10	140	114	wfo	wfo	PROPN
gsrj-10	140	115	�	�	PROPN
gsrj-10	140	116	uipvhi	uipvhi	PROPN
gsrj-10	140	117	�	�	PROPN
gsrj-10	140	118	uif	uif	PROPN
gsrj-10	140	119	�	�	PROPN
gsrj-10	140	120	nfdibojtn	nfdibojtn	PROPN
gsrj-10	140	121	�	�	PROPN
gsrj-10	140	122	ibt	ibt	PROPN
gsrj-10	140	123	�	�	PROPN
gsrj-10	140	124	zfu	zfu	PROPN
gsrj-10	140	125	�	�	PROPN
gsrj-10	140	126	up	up	ADP
gsrj-10	140	127	�	�	PROPN
gsrj-10	140	128	cf	cf	NOUN
gsrj-10	140	129	�	�	PROPN
gsrj-10	140	130	gvmmz	gvmmz	PROPN
gsrj-10	140	131	�	�	PROPN
gsrj-10	140	132	fmvdjebufe	fmvdjebufe	PROPN
gsrj-10	140	133	�	�	PROPN
gsrj-10	140	134	uif	uif	PROPN
gsrj-10	140	135	�	�	PROPN
gsrj-10	140	136	sftvmut	sftvmut	PROPN
gsrj-10	140	137	�	�	PROPN
gsrj-10	140	138	tipx	tipx	PROPN
gsrj-10	140	139	�	�	PROPN
gsrj-10	140	140	uibu	uibu	ADJ
gsrj-10	140	141	�	�	PROPN
gsrj-10	140	142	%#4	%#4	PROPN
gsrj-10	140	143	�	�	PROPN
gsrj-10	140	144	sfevdft	sfevdft	PROPN
gsrj-10	140	145	�	�	PROPN
gsrj-10	140	146	boujefqsfttbou	boujefqsfttbou	PROPN
gsrj-10	140	147	�	�	PROPN
gsrj-10	140	148	mjlf	mjlf	PROPN
gsrj-10	140	149	�	�	PROPN
gsrj-10	140	150	tznqupnt	tznqupnt	PROPN
gsrj-10	140	151	�	�	PROPN
gsrj-10	140	152	xjuipvu	xjuipvu	PROPN
gsrj-10	140	153	�	�	PROPN
gsrj-10	140	154	zjfmejoh	zjfmejoh	PROPN
gsrj-10	140	155	�	�	PROPN
gsrj-10	140	156	tfwfsf	tfwfsf	PROPN
gsrj-10	140	157	�	�	PROPN
gsrj-10	140	158	ps	ps	SYM
gsrj-10	140	159	�	�	PROPN
gsrj-10	140	160	dpnnpo	dpnnpo	PROPN
gsrj-10	140	161	�	�	PROPN
gsrj-10	140	162	tjef	tjef	PROPN
gsrj-10	140	163	�	�	PROPN
gsrj-10	140	164	�	�	PROPN
gsrj-10	140	165	fggfdut	fggfdut	PROPN
gsrj-10	140	166	�	�	PROPN
gsrj-10	140	167	�	�	PROPN
gsrj-10	140	168	�	�	PROPN
gsrj-10	140	169	�	�	PROPN
gsrj-10	140	170	�	�	PROPN
gsrj-10	140	171	�	�	PROPN
gsrj-10	140	172	�	�	PROPN
gsrj-10	140	173	�	�	PROPN
gsrj-10	140	174	dbs	dbs	PROPN
gsrj-10	140	175	is	be	AUX
gsrj-10	140	176	a	a	DET
gsrj-10	140	177	promising	promising	ADJ
gsrj-10	140	178	future	future	ADJ
gsrj-10	140	179	direction	direction	NOUN
gsrj-10	140	180	given	give	VERB
gsrj-10	140	181	that	that	DET
gsrj-10	140	182	phasic	phasic	ADJ
gsrj-10	140	183	dopamine	dopamine	NOUN
gsrj-10	140	184	firing	fire	VERB
gsrj-10	140	185	in	in	ADP
gsrj-10	140	186	the	the	DET
gsrj-10	140	187	vta	vta	PROPN
gsrj-10	140	188	–	–	PUNCT
gsrj-10	140	189	nac	nac	PROPN
gsrj-10	140	190	pathway	pathway	NOUN
gsrj-10	140	191	leads	lead	VERB
gsrj-10	140	192	to	to	ADP
gsrj-10	140	193	depressive	depressive	ADJ
gsrj-10	140	194	features	feature	NOUN
gsrj-10	140	195	in	in	ADP
gsrj-10	140	196	mice	mouse	NOUN
gsrj-10	140	197	,	,	PUNCT
gsrj-10	140	198	which	which	PRON
gsrj-10	140	199	optogenetic	optogenetic	ADJ
gsrj-10	140	200	alterations	alteration	NOUN
gsrj-10	140	201	reduce	reduce	VERB
gsrj-10	140	202	.	.	PUNCT
gsrj-10	141	1	the	the	DET
gsrj-10	141	2	study	study	NOUN
gsrj-10	141	3	cited	cite	VERB
gsrj-10	141	4	makes	make	VERB
gsrj-10	141	5	evident	evident	ADJ
gsrj-10	141	6	that	that	SCONJ
gsrj-10	141	7	dbs	dbs	NOUN
gsrj-10	141	8	is	be	AUX
gsrj-10	141	9	surgically	surgically	ADV
gsrj-10	141	10	viable	viable	ADJ
gsrj-10	141	11	and	and	CCONJ
gsrj-10	141	12	potentially	potentially	ADV
gsrj-10	141	13	modulates	modulate	VERB
gsrj-10	141	14	the	the	DET
gsrj-10	141	15	vta	vta	PROPN
gsrj-10	141	16	–	–	PUNCT
gsrj-10	141	17	nac	nac	PROPN
gsrj-10	141	18	projection	projection	NOUN
gsrj-10	141	19	.	.	PUNCT
gsrj-10	142	1	if	if	SCONJ
gsrj-10	142	2	dbs	dbs	PROPN
gsrj-10	142	3	can	can	AUX
gsrj-10	142	4	alter	alter	VERB
gsrj-10	142	5	dopamine	dopamine	NOUN
gsrj-10	142	6	in	in	ADP
gsrj-10	142	7	the	the	DET
gsrj-10	142	8	vta	vta	NOUN
gsrj-10	142	9	,	,	PUNCT
gsrj-10	142	10	as	as	SCONJ
gsrj-10	142	11	proposed	propose	VERB
gsrj-10	142	12	,	,	PUNCT
gsrj-10	142	13	then	then	ADV
gsrj-10	142	14	this	this	DET
gsrj-10	142	15	therapy	therapy	NOUN
gsrj-10	142	16	is	be	AUX
gsrj-10	142	17	especially	especially	ADV
gsrj-10	142	18	promising	promising	ADJ
gsrj-10	142	19	.	.	PUNCT
gsrj-10	143	1	5.	5.	X
gsrj-10	143	2	�	�	NOUN
gsrj-10	143	3	sleep	sleep	NOUN
gsrj-10	143	4	disorders	disorder	NOUN
gsrj-10	143	5	:	:	PUNCT
gsrj-10	143	6	contribution	contribution	NOUN
gsrj-10	143	7	of	of	ADP
gsrj-10	143	8	dopamine	dopamine	NOUN
gsrj-10	143	9	in	in	ADP
gsrj-10	143	10	�	�	PROPN
gsrj-10	143	11	the	the	DET
gsrj-10	143	12	vta	vta	PROPN
gsrj-10	143	13	nac	nac	PROPN
gsrj-10	143	14	pathway	pathway	NOUN
gsrj-10	143	15	it	it	PRON
gsrj-10	143	16	has	have	AUX
gsrj-10	143	17	been	be	AUX
gsrj-10	143	18	shown	show	VERB
gsrj-10	143	19	that	that	SCONJ
gsrj-10	143	20	nicotine	nicotine	NOUN
gsrj-10	143	21	users	user	NOUN
gsrj-10	143	22	experience	experience	NOUN
gsrj-10	143	23	decreased	decrease	VERB
gsrj-10	143	24	sleep	sleep	NOUN
gsrj-10	143	25	quality.29	quality.29	NOUN
gsrj-10	143	26	since	since	SCONJ
gsrj-10	143	27	morel	morel	PROPN
gsrj-10	143	28	et	et	PROPN
gsrj-10	143	29	al	al	PROPN
gsrj-10	143	30	.	.	PROPN
gsrj-10	143	31	focus	focus	VERB
gsrj-10	143	32	on	on	ADP
gsrj-10	143	33	how	how	SCONJ
gsrj-10	143	34	nachrs	nachrs	ADJ
gsrj-10	143	35	mediate	mediate	VERB
gsrj-10	143	36	the	the	DET
gsrj-10	143	37	combined	combined	ADJ
gsrj-10	143	38	effect	effect	NOUN
gsrj-10	143	39	of	of	ADP
gsrj-10	143	40	stress	stress	NOUN
gsrj-10	143	41	and	and	CCONJ
gsrj-10	143	42	nicotine	nicotine	NOUN
gsrj-10	143	43	by	by	ADP
gsrj-10	143	44	altering	alter	VERB
gsrj-10	143	45	the	the	DET
gsrj-10	143	46	activity	activity	NOUN
gsrj-10	143	47	of	of	ADP
gsrj-10	143	48	da	da	ADJ
gsrj-10	143	49	neurons	neuron	NOUN
gsrj-10	143	50	in	in	ADP
gsrj-10	143	51	the	the	DET
gsrj-10	143	52	vta	vta	NOUN
gsrj-10	143	53	,	,	PUNCT
gsrj-10	143	54	this	this	DET
gsrj-10	143	55	activity	activity	NOUN
gsrj-10	143	56	may	may	AUX
gsrj-10	143	57	also	also	ADV
gsrj-10	143	58	affect	affect	VERB
gsrj-10	143	59	sleep	sleep	NOUN
gsrj-10	143	60	disorders	disorder	NOUN
gsrj-10	143	61	.	.	PUNCT
gsrj-10	144	1	in	in	ADP
gsrj-10	144	2	addition	addition	NOUN
gsrj-10	144	3	to	to	ADP
gsrj-10	144	4	the	the	DET
gsrj-10	144	5	stress	stress	NOUN
gsrj-10	144	6	and	and	CCONJ
gsrj-10	144	7	depression	depression	NOUN
gsrj-10	144	8	effects	effect	NOUN
gsrj-10	144	9	of	of	ADP
gsrj-10	144	10	altered	altered	ADJ
gsrj-10	144	11	da	da	NOUN
gsrj-10	144	12	signaling	signal	VERB
gsrj-10	144	13	in	in	ADP
gsrj-10	144	14	the	the	DET
gsrj-10	144	15	79	79	NUM
gsrj-10	144	16	georgetown	georgetown	NOUN
gsrj-10	144	17	scientific	scientific	PROPN
gsrj-10	144	18	research	research	PROPN
gsrj-10	144	19	journal	journal	PROPN
gsrj-10	144	20	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	144	21	vta	vta	PROPN
gsrj-10	144	22	,	,	PUNCT
gsrj-10	144	23	da	da	PROPN
gsrj-10	144	24	regulates	regulate	VERB
gsrj-10	144	25	motivational	motivational	ADJ
gsrj-10	144	26	processes	process	NOUN
gsrj-10	144	27	via	via	ADP
gsrj-10	144	28	this	this	DET
gsrj-10	144	29	pathway	pathway	NOUN
gsrj-10	144	30	.	.	PUNCT
gsrj-10	145	1	da	da	ADJ
gsrj-10	145	2	neurons	neuron	NOUN
gsrj-10	145	3	project	project	NOUN
gsrj-10	145	4	from	from	ADP
gsrj-10	145	5	the	the	DET
gsrj-10	145	6	vta	vta	NOUN
gsrj-10	145	7	to	to	ADP
gsrj-10	145	8	many	many	ADJ
gsrj-10	145	9	brain	brain	NOUN
gsrj-10	145	10	regions	region	NOUN
gsrj-10	145	11	(	(	PUNCT
gsrj-10	145	12	figure	figure	NOUN
gsrj-10	145	13	6	6	NUM
gsrj-10	145	14	)	)	PUNCT
gsrj-10	145	15	.	.	PUNCT
gsrj-10	146	1	to	to	PART
gsrj-10	146	2	study	study	VERB
gsrj-10	146	3	how	how	SCONJ
gsrj-10	146	4	the	the	DET
gsrj-10	146	5	vta	vta	PROPN
gsrj-10	146	6	—	—	PUNCT
gsrj-10	146	7	nac	nac	PROPN
gsrj-10	146	8	pathway	pathway	NOUN
gsrj-10	146	9	specifically	specifically	ADV
gsrj-10	146	10	alters	alter	VERB
gsrj-10	146	11	sleep	sleep	NOUN
gsrj-10	146	12	,	,	PUNCT
gsrj-10	146	13	researchers	researcher	NOUN
gsrj-10	146	14	used	use	VERB
gsrj-10	146	15	chemogenetic	chemogenetic	ADJ
gsrj-10	146	16	and	and	CCONJ
gsrj-10	146	17	optogenetic	optogenetic	ADJ
gsrj-10	146	18	manipulations	manipulation	NOUN
gsrj-10	146	19	with	with	ADP
gsrj-10	146	20	polysomnographic	polysomnographic	ADJ
gsrj-10	146	21	recordings.30	recordings.30	NOUN
gsrj-10	146	22	these	these	DET
gsrj-10	146	23	recordings	recording	NOUN
gsrj-10	146	24	are	be	AUX
gsrj-10	146	25	a	a	DET
gsrj-10	146	26	diagnostic	diagnostic	ADJ
gsrj-10	146	27	test	test	NOUN
gsrj-10	146	28	used	use	VERB
gsrj-10	146	29	in	in	ADP
gsrj-10	146	30	sleep	sleep	NOUN
gsrj-10	146	31	medicine	medicine	NOUN
gsrj-10	146	32	to	to	PART
gsrj-10	146	33	comprehensively	comprehensively	ADV
gsrj-10	146	34	record	record	VERB
gsrj-10	146	35	physiological	physiological	ADJ
gsrj-10	146	36	changes	change	NOUN
gsrj-10	146	37	during	during	ADP
gsrj-10	146	38	sleep	sleep	NOUN
gsrj-10	146	39	.	.	PUNCT
gsrj-10	147	1	chemogenetics	chemogenetic	NOUN
gsrj-10	147	2	is	be	AUX
gsrj-10	147	3	similar	similar	ADJ
gsrj-10	147	4	to	to	ADP
gsrj-10	147	5	optogenetics	optogenetics	NOUN
gsrj-10	147	6	but	but	CCONJ
gsrj-10	147	7	uses	use	VERB
gsrj-10	147	8	chemically	chemically	ADV
gsrj-10	147	9	engineered	engineer	VERB
gsrj-10	147	10	molecules	molecule	NOUN
gsrj-10	147	11	and	and	CCONJ
gsrj-10	147	12	ligands	ligand	NOUN
gsrj-10	147	13	instead	instead	ADV
gsrj-10	147	14	of	of	ADP
gsrj-10	147	15	light	light	NOUN
gsrj-10	147	16	and	and	CCONJ
gsrj-10	147	17	light	light	ADJ
gsrj-10	147	18	-	-	PUNCT
gsrj-10	147	19	sensitive	sensitive	ADJ
gsrj-10	147	20	channels	channel	NOUN
gsrj-10	147	21	(	(	PUNCT
gsrj-10	147	22	opsins	opsin	NOUN
gsrj-10	147	23	)	)	PUNCT
gsrj-10	147	24	.	.	PUNCT
gsrj-10	148	1	these	these	DET
gsrj-10	148	2	methods	method	NOUN
gsrj-10	148	3	provide	provide	VERB
gsrj-10	148	4	incredible	incredible	ADJ
gsrj-10	148	5	techniques	technique	NOUN
gsrj-10	148	6	to	to	PART
gsrj-10	148	7	study	study	VERB
gsrj-10	148	8	the	the	DET
gsrj-10	148	9	relationship	relationship	NOUN
gsrj-10	148	10	between	between	ADP
gsrj-10	148	11	neuronal	neuronal	ADJ
gsrj-10	148	12	activity	activity	NOUN
gsrj-10	148	13	and	and	CCONJ
gsrj-10	148	14	behavior	behavior	NOUN
gsrj-10	148	15	.	.	PUNCT
gsrj-10	149	1	vta	vta	PROPN
gsrj-10	149	2	dopamine	dopamine	PROPN
gsrj-10	149	3	neurons	neuron	NOUN
gsrj-10	149	4	have	have	AUX
gsrj-10	149	5	been	be	AUX
gsrj-10	149	6	found	find	VERB
gsrj-10	149	7	to	to	PART
gsrj-10	149	8	undergo	undergo	VERB
gsrj-10	149	9	changes	change	NOUN
gsrj-10	149	10	in	in	ADP
gsrj-10	149	11	firing	fire	VERB
gsrj-10	149	12	in	in	ADP
gsrj-10	149	13	rapid	rapid	ADJ
gsrj-10	149	14	eye	eye	NOUN
gsrj-10	149	15	movement	movement	NOUN
gsrj-10	149	16	(	(	PUNCT
gsrj-10	149	17	rem	rem	NOUN
gsrj-10	149	18	)	)	PUNCT
gsrj-10	149	19	sleep	sleep	NOUN
gsrj-10	149	20	and	and	CCONJ
gsrj-10	149	21	non	non	ADJ
gsrj-10	149	22	-	-	ADJ
gsrj-10	149	23	rem	rem	ADJ
gsrj-10	149	24	(	(	PUNCT
gsrj-10	149	25	nrem	nrem	PROPN
gsrj-10	149	26	)	)	PUNCT
gsrj-10	149	27	sleep	sleep	NOUN
gsrj-10	149	28	,	,	PUNCT
gsrj-10	149	29	making	make	VERB
gsrj-10	149	30	them	they	PRON
gsrj-10	149	31	interesting	interesting	ADJ
gsrj-10	149	32	candidates	candidate	NOUN
gsrj-10	149	33	to	to	PART
gsrj-10	149	34	further	far	ADV
gsrj-10	149	35	examine	examine	VERB
gsrj-10	149	36	.	.	PUNCT
gsrj-10	150	1	through	through	ADP
gsrj-10	150	2	complex	complex	ADJ
gsrj-10	150	3	analysis	analysis	NOUN
gsrj-10	150	4	of	of	ADP
gsrj-10	150	5	da	da	PROPN
gsrj-10	150	6	neuron	neuron	NOUN
gsrj-10	150	7	activity	activity	NOUN
gsrj-10	150	8	in	in	ADP
gsrj-10	150	9	vta	vta	PROPN
gsrj-10	150	10	projections	projection	NOUN
gsrj-10	150	11	,	,	PUNCT
gsrj-10	150	12	researchers	researcher	NOUN
gsrj-10	150	13	found	find	VERB
gsrj-10	150	14	that	that	SCONJ
gsrj-10	150	15	these	these	DET
gsrj-10	150	16	neurons	neuron	NOUN
gsrj-10	150	17	are	be	AUX
gsrj-10	150	18	altered	alter	VERB
gsrj-10	150	19	by	by	ADP
gsrj-10	150	20	different	different	ADJ
gsrj-10	150	21	arousal	arousal	NOUN
gsrj-10	150	22	states	state	NOUN
gsrj-10	150	23	:	:	PUNCT
gsrj-10	150	24	in	in	ADP
gsrj-10	150	25	nrem	nrem	PROPN
gsrj-10	150	26	sleep	sleep	VERB
gsrj-10	150	27	their	their	PRON
gsrj-10	150	28	activity	activity	NOUN
gsrj-10	150	29	is	be	AUX
gsrj-10	150	30	reduced	reduce	VERB
gsrj-10	150	31	,	,	PUNCT
gsrj-10	150	32	and	and	CCONJ
gsrj-10	150	33	when	when	SCONJ
gsrj-10	150	34	active	active	ADJ
gsrj-10	150	35	they	they	PRON
gsrj-10	150	36	maintain	maintain	VERB
gsrj-10	150	37	long	long	ADJ
gsrj-10	150	38	-	-	PUNCT
gsrj-10	150	39	term	term	NOUN
gsrj-10	150	40	wakefulness	wakefulness	NOUN
gsrj-10	150	41	.	.	PUNCT
gsrj-10	151	1	overall	overall	ADJ
gsrj-10	151	2	,	,	PUNCT
gsrj-10	151	3	dopamine	dopamine	NOUN
gsrj-10	151	4	neurons	neuron	NOUN
gsrj-10	151	5	that	that	PRON
gsrj-10	151	6	project	project	NOUN
gsrj-10	151	7	from	from	ADP
gsrj-10	151	8	vta	vta	PROPN
gsrj-10	151	9	–	–	PUNCT
gsrj-10	151	10	nac	nac	PROPN
gsrj-10	151	11	promote	promote	VERB
gsrj-10	151	12	wakefulness	wakefulness	NOUN
gsrj-10	151	13	and	and	CCONJ
gsrj-10	151	14	suppress	suppress	VERB
gsrj-10	151	15	sleep	sleep	NOUN
gsrj-10	151	16	.	.	PUNCT
gsrj-10	152	1	selectively	selectively	ADV
gsrj-10	152	2	optogenetically	optogenetically	ADV
gsrj-10	152	3	activating	activate	VERB
gsrj-10	152	4	the	the	DET
gsrj-10	152	5	neurons	neuron	NOUN
gsrj-10	152	6	maintained	maintain	VERB
gsrj-10	152	7	wakefulness	wakefulness	NOUN
gsrj-10	152	8	and	and	CCONJ
gsrj-10	153	1	suppressed	suppress	VERB
gsrj-10	153	2	nest	nest	NOUN
gsrj-10	153	3	-	-	PUNCT
gsrj-10	153	4	building	building	NOUN
gsrj-10	153	5	behavior	behavior	NOUN
gsrj-10	153	6	,	,	PUNCT
gsrj-10	153	7	which	which	PRON
gsrj-10	153	8	is	be	AUX
gsrj-10	153	9	where	where	SCONJ
gsrj-10	153	10	mice	mouse	NOUN
gsrj-10	153	11	sleep	sleep	VERB
gsrj-10	153	12	.	.	PUNCT
gsrj-10	154	1	inhibiting	inhibit	VERB
gsrj-10	154	2	the	the	DET
gsrj-10	154	3	activity	activity	NOUN
gsrj-10	154	4	of	of	ADP
gsrj-10	154	5	these	these	DET
gsrj-10	154	6	neurons	neuron	NOUN
gsrj-10	154	7	promotes	promote	VERB
gsrj-10	154	8	sleeprelated	sleeprelate	VERB
gsrj-10	154	9	nesting	nesting	ADJ
gsrj-10	154	10	behavior	behavior	NOUN
gsrj-10	154	11	.	.	PUNCT
gsrj-10	155	1	even	even	ADV
gsrj-10	155	2	though	though	SCONJ
gsrj-10	155	3	this	this	DET
gsrj-10	155	4	study	study	NOUN
gsrj-10	155	5	examined	examine	VERB
gsrj-10	155	6	the	the	DET
gsrj-10	155	7	vta	vta	PROPN
gsrj-10	155	8	projections	projection	NOUN
gsrj-10	155	9	to	to	ADP
gsrj-10	155	10	the	the	DET
gsrj-10	155	11	nac	nac	PROPN
gsrj-10	155	12	,	,	PUNCT
gsrj-10	155	13	prefrontal	prefrontal	ADJ
gsrj-10	155	14	cortex	cortex	NOUN
gsrj-10	155	15	,	,	PUNCT
gsrj-10	155	16	amygdala	amygdala	NOUN
gsrj-10	155	17	,	,	PUNCT
gsrj-10	155	18	and	and	CCONJ
gsrj-10	155	19	dorsolateral	dorsolateral	ADJ
gsrj-10	155	20	striatum	striatum	NOUN
gsrj-10	155	21	,	,	PUNCT
gsrj-10	155	22	the	the	DET
gsrj-10	155	23	nac	nac	PROPN
gsrj-10	155	24	was	be	AUX
gsrj-10	155	25	the	the	DET
gsrj-10	155	26	only	only	ADJ
gsrj-10	155	27	projection	projection	NOUN
gsrj-10	155	28	that	that	PRON
gsrj-10	155	29	stimulated	stimulate	VERB
gsrj-10	155	30	arousal	arousal	NOUN
gsrj-10	155	31	.	.	PUNCT
gsrj-10	156	1	the	the	DET
gsrj-10	156	2	nac	nac	PROPN
gsrj-10	156	3	increased	increase	VERB
gsrj-10	156	4	wakefulness	wakefulness	NOUN
gsrj-10	156	5	and	and	CCONJ
gsrj-10	156	6	decreased	decrease	VERB
gsrj-10	156	7	nrem	nrem	PROPN
gsrj-10	156	8	and	and	CCONJ
gsrj-10	156	9	rem	rem	X
gsrj-10	156	10	sleep	sleep	NOUN
gsrj-10	156	11	.	.	PUNCT
gsrj-10	157	1	while	while	SCONJ
gsrj-10	157	2	other	other	ADJ
gsrj-10	157	3	pathways	pathway	NOUN
gsrj-10	157	4	such	such	ADJ
gsrj-10	157	5	as	as	ADP
gsrj-10	157	6	the	the	DET
gsrj-10	157	7	prefrontal	prefrontal	ADJ
gsrj-10	157	8	cortex	cortex	NOUN
gsrj-10	157	9	have	have	VERB
gsrj-10	157	10	a	a	DET
gsrj-10	157	11	larger	large	ADJ
gsrj-10	157	12	effect	effect	NOUN
gsrj-10	157	13	on	on	ADP
gsrj-10	157	14	rem	rem	VERB
gsrj-10	157	15	duration	duration	NOUN
gsrj-10	157	16	,	,	PUNCT
gsrj-10	157	17	nac	nac	PROPN
gsrj-10	157	18	was	be	AUX
gsrj-10	157	19	still	still	ADV
gsrj-10	157	20	�	�	PROPN
gsrj-10	157	21	tjhojgjdbou	tjhojgjdbou	PROPN
gsrj-10	157	22	�	�	PROPN
gsrj-10	157	23	jo	jo	PROPN
gsrj-10	157	24	�	�	PROPN
gsrj-10	157	25	npevmbujoh	npevmbujoh	PROPN
gsrj-10	157	26	�	�	PROPN
gsrj-10	157	27	bspvtbm	bspvtbm	PROPN
gsrj-10	157	28	�	�	PROPN
gsrj-10	157	29	�	�	PROPN
gsrj-10	157	30	�	�	PROPN
gsrj-10	157	31	�	�	PROPN
gsrj-10	157	32	�	�	PROPN
gsrj-10	157	33	�	�	PROPN
gsrj-10	157	34	�	�	PROPN
gsrj-10	157	35	5iftf	5iftf	NUM
gsrj-10	157	36	�	�	PROPN
gsrj-10	157	37	gjoejoht	gjoejoht	PROPN
gsrj-10	157	38	�	�	PROPN
gsrj-10	157	39	bsf	bsf	PROPN
gsrj-10	157	40	�	�	PROPN
gsrj-10	157	41	jnqpsubou	jnqpsubou	PROPN
gsrj-10	157	42	�	�	PROPN
gsrj-10	157	43	cfdbvtf	cfdbvtf	PROPN
gsrj-10	157	44	�	�	PROPN
gsrj-10	157	45	uifzimplicate	uifzimplicate	PROPN
gsrj-10	157	46	vta	vta	PROPN
gsrj-10	157	47	dopamine	dopamine	NOUN
gsrj-10	157	48	in	in	ADP
gsrj-10	157	49	mediating	mediate	VERB
gsrj-10	157	50	stress	stress	NOUN
gsrj-10	157	51	and	and	CCONJ
gsrj-10	157	52	sleep	sleep	NOUN
gsrj-10	157	53	-	-	PUNCT
gsrj-10	157	54	like	like	ADJ
gsrj-10	157	55	behaviors	behavior	NOUN
gsrj-10	157	56	.	.	PUNCT
gsrj-10	158	1	nicotine	nicotine	NOUN
gsrj-10	158	2	,	,	PUNCT
gsrj-10	158	3	as	as	SCONJ
gsrj-10	158	4	established	establish	VERB
gsrj-10	158	5	by	by	ADP
gsrj-10	158	6	morel	morel	PROPN
gsrj-10	158	7	et	et	PROPN
gsrj-10	158	8	al	al	PROPN
gsrj-10	158	9	.	.	PROPN
gsrj-10	158	10	,	,	PUNCT
gsrj-10	158	11	increases	increase	VERB
gsrj-10	158	12	the	the	DET
gsrj-10	158	13	activity	activity	NOUN
gsrj-10	158	14	of	of	ADP
gsrj-10	158	15	these	these	DET
gsrj-10	158	16	da	da	ADJ
gsrj-10	158	17	neurons	neuron	NOUN
gsrj-10	158	18	,	,	PUNCT
gsrj-10	158	19	which	which	PRON
gsrj-10	158	20	induces	induce	VERB
gsrj-10	158	21	stress	stress	NOUN
gsrj-10	158	22	-	-	PUNCT
gsrj-10	158	23	like	like	ADJ
gsrj-10	158	24	behavior	behavior	NOUN
gsrj-10	158	25	as	as	ADP
gsrj-10	158	26	a	a	DET
gsrj-10	158	27	symptom	symptom	NOUN
gsrj-10	158	28	of	of	ADP
gsrj-10	158	29	depression	depression	NOUN
gsrj-10	158	30	.	.	PUNCT
gsrj-10	159	1	it	it	PRON
gsrj-10	159	2	is	be	AUX
gsrj-10	159	3	also	also	ADV
gsrj-10	159	4	possible	possible	ADJ
gsrj-10	159	5	that	that	SCONJ
gsrj-10	159	6	the	the	DET
gsrj-10	159	7	same	same	ADJ
gsrj-10	159	8	mechanism	mechanism	NOUN
gsrj-10	159	9	leads	lead	VERB
gsrj-10	159	10	to	to	ADP
gsrj-10	159	11	heightened	heightened	ADJ
gsrj-10	159	12	arousal	arousal	NOUN
gsrj-10	159	13	-	-	PUNCT
gsrj-10	159	14	like	like	ADJ
gsrj-10	159	15	states	state	NOUN
gsrj-10	159	16	,	,	PUNCT
gsrj-10	159	17	hurting	hurt	VERB
gsrj-10	159	18	the	the	DET
gsrj-10	159	19	ability	ability	NOUN
gsrj-10	159	20	to	to	PART
gsrj-10	159	21	sleep	sleep	VERB
gsrj-10	159	22	.	.	PUNCT
gsrj-10	160	1	a	a	DET
gsrj-10	160	2	recent	recent	ADJ
gsrj-10	160	3	survey	survey	NOUN
gsrj-10	160	4	-	-	PUNCT
gsrj-10	160	5	based	base	VERB
gsrj-10	160	6	study	study	NOUN
gsrj-10	160	7	found	find	VERB
gsrj-10	160	8	that	that	SCONJ
gsrj-10	160	9	college	college	NOUN
gsrj-10	160	10	students	student	NOUN
gsrj-10	160	11	who	who	PRON
gsrj-10	160	12	use	use	VERB
gsrj-10	160	13	electronic	electronic	ADJ
gsrj-10	160	14	cigarettes	cigarette	NOUN
gsrj-10	160	15	report	report	VERB
gsrj-10	160	16	significantly	significantly	ADV
gsrj-10	160	17	higher	high	ADJ
gsrj-10	160	18	difficulty	difficulty	NOUN
gsrj-10	160	19	sleeping	sleep	VERB
gsrj-10	160	20	compared	compare	VERB
gsrj-10	160	21	to	to	ADP
gsrj-10	160	22	non	non	ADJ
gsrj-10	160	23	-	-	NOUN
gsrj-10	160	24	users.29	users.29	NOUN
gsrj-10	160	25	interestingly	interestingly	ADV
gsrj-10	160	26	,	,	PUNCT
gsrj-10	160	27	electronic	electronic	ADJ
gsrj-10	160	28	cigarette	cigarette	NOUN
gsrj-10	160	29	users	user	NOUN
gsrj-10	160	30	also	also	ADV
gsrj-10	160	31	report	report	VERB
gsrj-10	160	32	more	more	ADJ
gsrj-10	160	33	difficulty	difficulty	NOUN
gsrj-10	160	34	sleeping	sleep	VERB
gsrj-10	160	35	compared	compare	VERB
gsrj-10	160	36	to	to	ADP
gsrj-10	160	37	traditional	traditional	ADJ
gsrj-10	160	38	cigarette	cigarette	NOUN
gsrj-10	160	39	users	user	NOUN
gsrj-10	160	40	,	,	PUNCT
gsrj-10	160	41	suggesting	suggest	VERB
gsrj-10	160	42	that	that	SCONJ
gsrj-10	160	43	electronic	electronic	ADJ
gsrj-10	160	44	cigarettes	cigarette	NOUN
gsrj-10	160	45	may	may	AUX
gsrj-10	160	46	be	be	AUX
gsrj-10	160	47	more	more	ADV
gsrj-10	160	48	potent	potent	ADJ
gsrj-10	160	49	for	for	ADP
gsrj-10	160	50	nicotine	nicotine	NOUN
gsrj-10	160	51	than	than	ADP
gsrj-10	160	52	traditional	traditional	ADJ
gsrj-10	160	53	cigarettes	cigarette	NOUN
gsrj-10	160	54	and	and	CCONJ
gsrj-10	160	55	thus	thus	ADV
gsrj-10	160	56	may	may	AUX
gsrj-10	160	57	pose	pose	VERB
gsrj-10	160	58	an	an	DET
gsrj-10	160	59	increased	increased	ADJ
gsrj-10	160	60	risk	risk	NOUN
gsrj-10	160	61	for	for	ADP
gsrj-10	160	62	the	the	DET
gsrj-10	160	63	side	side	NOUN
gsrj-10	160	64	effects	effect	NOUN
gsrj-10	160	65	of	of	ADP
gsrj-10	160	66	nicotine	nicotine	NOUN
gsrj-10	160	67	.	.	PUNCT
gsrj-10	161	1	taken	take	VERB
gsrj-10	161	2	together	together	ADV
gsrj-10	161	3	,	,	PUNCT
gsrj-10	161	4	nicotine	nicotine	PROPN
gsrj-10	161	5	’s	’s	PART
gsrj-10	161	6	effect	effect	NOUN
gsrj-10	161	7	on	on	ADP
gsrj-10	161	8	da	da	NOUN
gsrj-10	161	9	firing	firing	NOUN
gsrj-10	161	10	has	have	VERB
gsrj-10	161	11	extensive	extensive	ADJ
gsrj-10	161	12	implications	implication	NOUN
gsrj-10	161	13	,	,	PUNCT
gsrj-10	161	14	which	which	PRON
gsrj-10	161	15	likely	likely	ADV
gsrj-10	161	16	contribute	contribute	VERB
gsrj-10	161	17	to	to	ADP
gsrj-10	161	18	sleep	sleep	NOUN
gsrj-10	161	19	difficulty	difficulty	NOUN
gsrj-10	161	20	.	.	PUNCT
gsrj-10	162	1	conclusion	conclusion	VERB
gsrj-10	162	2	the	the	DET
gsrj-10	162	3	combination	combination	NOUN
gsrj-10	162	4	of	of	ADP
gsrj-10	162	5	social	social	ADJ
gsrj-10	162	6	stress	stress	NOUN
gsrj-10	162	7	and	and	CCONJ
gsrj-10	162	8	nicotine	nicotine	VERB
gsrj-10	162	9	binding	bind	VERB
gsrj-10	162	10	to	to	ADP
gsrj-10	162	11	acetylcholine	acetylcholine	NOUN
gsrj-10	162	12	receptors	receptor	NOUN
gsrj-10	162	13	in	in	ADP
gsrj-10	162	14	the	the	DET
gsrj-10	162	15	vta	vta	PROPN
gsrj-10	162	16	modulates	modulate	NOUN
gsrj-10	162	17	da	da	NOUN
gsrj-10	162	18	firing	fire	VERB
gsrj-10	162	19	through	through	ADP
gsrj-10	162	20	various	various	ADJ
gsrj-10	162	21	synaptic	synaptic	ADJ
gsrj-10	162	22	mechanisms	mechanism	NOUN
gsrj-10	162	23	.	.	PUNCT
gsrj-10	163	1	modulations	modulation	NOUN
gsrj-10	163	2	in	in	ADP
gsrj-10	163	3	da	da	NOUN
gsrj-10	163	4	firing	fire	VERB
gsrj-10	163	5	in	in	ADP
gsrj-10	163	6	the	the	DET
gsrj-10	163	7	vta	vta	PROPN
gsrj-10	163	8	have	have	VERB
gsrj-10	163	9	broad	broad	ADJ
gsrj-10	163	10	implications	implication	NOUN
gsrj-10	163	11	related	relate	VERB
gsrj-10	163	12	to	to	ADP
gsrj-10	163	13	several	several	ADJ
gsrj-10	163	14	mood	mood	NOUN
gsrj-10	163	15	and	and	CCONJ
gsrj-10	163	16	sleep	sleep	NOUN
gsrj-10	163	17	disorders	disorder	NOUN
gsrj-10	163	18	.	.	PUNCT
gsrj-10	164	1	this	this	DET
gsrj-10	164	2	social	social	ADJ
gsrj-10	164	3	stressnicotine	stressnicotine	ADJ
gsrj-10	164	4	bidirectional	bidirectional	ADJ
gsrj-10	164	5	interplay	interplay	NOUN
gsrj-10	164	6	supports	support	VERB
gsrj-10	164	7	and	and	CCONJ
gsrj-10	164	8	partially	partially	ADV
gsrj-10	164	9	explains	explain	VERB
gsrj-10	164	10	the	the	DET
gsrj-10	164	11	strong	strong	ADJ
gsrj-10	164	12	association	association	NOUN
gsrj-10	164	13	between	between	ADP
gsrj-10	164	14	behavioral	behavioral	ADJ
gsrj-10	164	15	disorders	disorder	NOUN
gsrj-10	164	16	and	and	CCONJ
gsrj-10	164	17	nicotine	nicotine	NOUN
gsrj-10	164	18	addiction	addiction	NOUN
gsrj-10	164	19	.	.	PUNCT
gsrj-10	165	1	the	the	DET
gsrj-10	165	2	data	datum	NOUN
gsrj-10	165	3	presented	present	VERB
gsrj-10	165	4	in	in	ADP
gsrj-10	165	5	this	this	DET
gsrj-10	165	6	paper	paper	NOUN
gsrj-10	165	7	thus	thus	ADV
gsrj-10	165	8	demonstrate	demonstrate	VERB
gsrj-10	165	9	a	a	DET
gsrj-10	165	10	comorbidity	comorbidity	NOUN
gsrj-10	165	11	between	between	ADP
gsrj-10	165	12	social	social	ADJ
gsrj-10	165	13	stress	stress	NOUN
gsrj-10	165	14	and	and	CCONJ
gsrj-10	165	15	nicotine	nicotine	ADJ
gsrj-10	165	16	dependence	dependence	NOUN
gsrj-10	165	17	:	:	PUNCT
gsrj-10	165	18	a	a	DET
gsrj-10	165	19	pattern	pattern	NOUN
gsrj-10	165	20	wherein	wherein	SCONJ
gsrj-10	165	21	both	both	DET
gsrj-10	165	22	pathologies	pathology	NOUN
gsrj-10	165	23	enhance	enhance	VERB
gsrj-10	165	24	the	the	DET
gsrj-10	165	25	other	other	ADJ
gsrj-10	165	26	.	.	PUNCT
gsrj-10	166	1	elucidating	elucidate	VERB
gsrj-10	166	2	the	the	DET
gsrj-10	166	3	synaptic	synaptic	ADJ
gsrj-10	166	4	link	link	NOUN
gsrj-10	166	5	between	between	ADP
gsrj-10	166	6	the	the	DET
gsrj-10	166	7	disorders	disorder	NOUN
gsrj-10	166	8	has	have	VERB
gsrj-10	166	9	therapeutic	therapeutic	ADJ
gsrj-10	166	10	implications	implication	NOUN
gsrj-10	166	11	as	as	ADV
gsrj-10	166	12	well	well	ADV
gsrj-10	166	13	,	,	PUNCT
gsrj-10	166	14	where	where	SCONJ
gsrj-10	166	15	modulation	modulation	NOUN
gsrj-10	166	16	of	of	ADP
gsrj-10	166	17	dopamine	dopamine	NOUN
gsrj-10	166	18	activity	activity	NOUN
gsrj-10	166	19	via	via	ADP
gsrj-10	166	20	dbs	dbs	PROPN
gsrj-10	166	21	or	or	CCONJ
gsrj-10	166	22	antagonistic	antagonistic	ADJ
gsrj-10	166	23	binding	binding	NOUN
gsrj-10	166	24	to	to	ADP
gsrj-10	166	25	acetylcholine	acetylcholine	NOUN
gsrj-10	166	26	receptors	receptor	NOUN
gsrj-10	166	27	may	may	AUX
gsrj-10	166	28	reduce	reduce	VERB
gsrj-10	166	29	the	the	DET
gsrj-10	166	30	stress	stress	NOUN
gsrj-10	166	31	and	and	CCONJ
gsrj-10	166	32	depressive	depressive	ADJ
gsrj-10	166	33	symptoms	symptom	NOUN
gsrj-10	166	34	that	that	SCONJ
gsrj-10	166	35	these	these	DET
gsrj-10	166	36	mechanisms	mechanism	NOUN
gsrj-10	166	37	are	be	AUX
gsrj-10	166	38	sufficient	sufficient	ADJ
gsrj-10	166	39	to	to	PART
gsrj-10	166	40	induce	induce	VERB
gsrj-10	166	41	.	.	PUNCT
gsrj-10	167	1	the	the	DET
gsrj-10	167	2	complexity	complexity	NOUN
gsrj-10	167	3	of	of	ADP
gsrj-10	167	4	these	these	DET
gsrj-10	167	5	mood	mood	NOUN
gsrj-10	167	6	-	-	PUNCT
gsrj-10	167	7	responses	response	NOUN
gsrj-10	167	8	80	80	NUM
gsrj-10	167	9	georgetown	georgetown	NOUN
gsrj-10	167	10	scientific	scientific	ADJ
gsrj-10	167	11	research	research	NOUN
gsrj-10	167	12	journal	journal	PROPN
gsrj-10	167	13	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	167	14	are	be	AUX
gsrj-10	167	15	mediated	mediate	VERB
gsrj-10	167	16	by	by	ADP
gsrj-10	167	17	diverse	diverse	ADJ
gsrj-10	167	18	neural	neural	ADJ
gsrj-10	167	19	,	,	PUNCT
gsrj-10	167	20	endocrine	endocrine	NOUN
gsrj-10	167	21	,	,	PUNCT
gsrj-10	167	22	and	and	CCONJ
gsrj-10	167	23	physiological	physiological	ADJ
gsrj-10	167	24	pathways	pathway	NOUN
gsrj-10	167	25	,	,	PUNCT
gsrj-10	167	26	which	which	PRON
gsrj-10	167	27	leaves	leave	VERB
gsrj-10	167	28	a	a	DET
gsrj-10	167	29	lot	lot	NOUN
gsrj-10	167	30	of	of	ADP
gsrj-10	167	31	mechanisms	mechanism	NOUN
gsrj-10	167	32	and	and	CCONJ
gsrj-10	167	33	connections	connection	NOUN
gsrj-10	167	34	unknown	unknown	ADJ
gsrj-10	167	35	.	.	PUNCT
gsrj-10	168	1	further	far	ADV
gsrj-10	168	2	investigating	investigate	VERB
gsrj-10	168	3	the	the	DET
gsrj-10	168	4	connections	connection	NOUN
gsrj-10	168	5	between	between	ADP
gsrj-10	168	6	drugs	drug	NOUN
gsrj-10	168	7	and	and	CCONJ
gsrj-10	168	8	the	the	DET
gsrj-10	168	9	environment	environment	NOUN
gsrj-10	168	10	,	,	PUNCT
gsrj-10	168	11	and	and	CCONJ
gsrj-10	168	12	the	the	DET
gsrj-10	168	13	effects	effect	NOUN
gsrj-10	168	14	they	they	PRON
gsrj-10	168	15	have	have	VERB
gsrj-10	168	16	on	on	ADP
gsrj-10	168	17	synapses	synapsis	NOUN
gsrj-10	168	18	,	,	PUNCT
gsrj-10	168	19	will	will	AUX
gsrj-10	168	20	uncover	uncover	VERB
gsrj-10	168	21	more	more	ADJ
gsrj-10	168	22	of	of	ADP
gsrj-10	168	23	the	the	DET
gsrj-10	168	24	mechanisms	mechanism	NOUN
gsrj-10	168	25	by	by	ADP
gsrj-10	168	26	which	which	PRON
gsrj-10	168	27	a	a	DET
gsrj-10	168	28	broad	broad	ADJ
gsrj-10	168	29	range	range	NOUN
gsrj-10	168	30	of	of	ADP
gsrj-10	168	31	mood	mood	NOUN
gsrj-10	168	32	disorders	disorder	NOUN
gsrj-10	168	33	arise	arise	VERB
gsrj-10	168	34	.	.	PUNCT
gsrj-10	169	1	the	the	DET
gsrj-10	169	2	importance	importance	NOUN
gsrj-10	169	3	of	of	ADP
gsrj-10	169	4	understanding	understand	VERB
gsrj-10	169	5	these	these	DET
gsrj-10	169	6	neural	neural	ADJ
gsrj-10	169	7	processes	process	NOUN
gsrj-10	169	8	is	be	AUX
gsrj-10	169	9	especially	especially	ADV
gsrj-10	169	10	important	important	ADJ
gsrj-10	169	11	today	today	NOUN
gsrj-10	169	12	,	,	PUNCT
gsrj-10	169	13	as	as	SCONJ
gsrj-10	169	14	nicotine	nicotine	NOUN
gsrj-10	169	15	vaping	vaping	NOUN
gsrj-10	169	16	rates	rate	NOUN
gsrj-10	169	17	have	have	AUX
gsrj-10	169	18	been	be	AUX
gsrj-10	169	19	rapidly	rapidly	ADV
gsrj-10	169	20	increasing	increase	VERB
gsrj-10	169	21	in	in	ADP
gsrj-10	169	22	the	the	DET
gsrj-10	169	23	united	united	PROPN
gsrj-10	169	24	states	states	PROPN
gsrj-10	169	25	.	.	PUNCT
gsrj-10	170	1	in	in	ADP
gsrj-10	170	2	2018	2018	NUM
gsrj-10	170	3	,	,	PUNCT
gsrj-10	170	4	a	a	DET
gsrj-10	170	5	steep	steep	ADJ
gsrj-10	170	6	increase	increase	NOUN
gsrj-10	170	7	in	in	ADP
gsrj-10	170	8	vaping	vaping	NOUN
gsrj-10	170	9	was	be	AUX
gsrj-10	170	10	observed	observe	VERB
gsrj-10	170	11	,	,	PUNCT
gsrj-10	170	12	with	with	SCONJ
gsrj-10	170	13	37	37	NUM
gsrj-10	170	14	%	%	NOUN
gsrj-10	170	15	of	of	ADP
gsrj-10	170	16	high	high	ADJ
gsrj-10	170	17	school	school	NOUN
gsrj-10	170	18	seniors	senior	NOUN
gsrj-10	170	19	reported	report	VERB
gsrj-10	170	20	vaping	vape	VERB
gsrj-10	170	21	activity.31	activity.31	NOUN
gsrj-10	170	22	in	in	ADP
gsrj-10	170	23	2019	2019	NUM
gsrj-10	170	24	,	,	PUNCT
gsrj-10	170	25	10.5	10.5	NUM
gsrj-10	170	26	%	%	NOUN
gsrj-10	170	27	of	of	ADP
gsrj-10	170	28	middle	middle	ADJ
gsrj-10	170	29	schoolers	schooler	NOUN
gsrj-10	170	30	and	and	CCONJ
gsrj-10	170	31	27.5	27.5	NUM
gsrj-10	170	32	%	%	NOUN
gsrj-10	170	33	of	of	ADP
gsrj-10	170	34	high	high	ADJ
gsrj-10	170	35	school	school	NOUN
gsrj-10	170	36	students	student	NOUN
gsrj-10	170	37	reported	report	VERB
gsrj-10	170	38	vaping	vaping	NOUN
gsrj-10	170	39	,	,	PUNCT
gsrj-10	170	40	an	an	DET
gsrj-10	170	41	alarming	alarming	ADJ
gsrj-10	170	42	increase	increase	NOUN
gsrj-10	170	43	from	from	ADP
gsrj-10	170	44	past	past	ADJ
gsrj-10	170	45	years.32	years.32	NOUN
gsrj-10	170	46	in	in	ADP
gsrj-10	170	47	many	many	ADJ
gsrj-10	170	48	cases	case	NOUN
gsrj-10	170	49	,	,	PUNCT
gsrj-10	170	50	these	these	DET
gsrj-10	170	51	students	student	NOUN
gsrj-10	170	52	do	do	AUX
gsrj-10	170	53	not	not	PART
gsrj-10	170	54	know	know	VERB
gsrj-10	170	55	that	that	SCONJ
gsrj-10	170	56	nicotine	nicotine	NOUN
gsrj-10	170	57	is	be	AUX
gsrj-10	170	58	contained	contain	VERB
gsrj-10	170	59	in	in	ADP
gsrj-10	170	60	their	their	PRON
gsrj-10	170	61	electronic	electronic	ADJ
gsrj-10	170	62	cigarettes	cigarette	NOUN
gsrj-10	170	63	,	,	PUNCT
gsrj-10	170	64	or	or	CCONJ
gsrj-10	170	65	do	do	AUX
gsrj-10	170	66	not	not	PART
gsrj-10	170	67	think	think	VERB
gsrj-10	170	68	that	that	SCONJ
gsrj-10	170	69	nicotine	nicotine	NOUN
gsrj-10	170	70	alone	alone	ADV
gsrj-10	170	71	is	be	AUX
gsrj-10	170	72	harmful	harmful	ADJ
gsrj-10	170	73	.	.	PUNCT
gsrj-10	171	1	discovering	discover	VERB
gsrj-10	171	2	these	these	DET
gsrj-10	171	3	synaptic	synaptic	ADJ
gsrj-10	171	4	mechanisms	mechanism	NOUN
gsrj-10	171	5	will	will	AUX
gsrj-10	171	6	demonstrate	demonstrate	VERB
gsrj-10	171	7	to	to	PART
gsrj-10	171	8	uninformed	uninformed	ADJ
gsrj-10	171	9	teens	teen	NOUN
gsrj-10	171	10	how	how	SCONJ
gsrj-10	171	11	nicotine	nicotine	NOUN
gsrj-10	171	12	is	be	AUX
gsrj-10	171	13	detrimental	detrimental	ADJ
gsrj-10	171	14	and	and	CCONJ
gsrj-10	171	15	can	can	AUX
gsrj-10	171	16	be	be	AUX
gsrj-10	171	17	a	a	DET
gsrj-10	171	18	risk	risk	NOUN
gsrj-10	171	19	factor	factor	NOUN
gsrj-10	171	20	for	for	ADP
gsrj-10	171	21	mood	mood	NOUN
gsrj-10	171	22	and	and	CCONJ
gsrj-10	171	23	sleep	sleep	NOUN
gsrj-10	171	24	disorders	disorder	NOUN
gsrj-10	171	25	,	,	PUNCT
gsrj-10	171	26	especially	especially	ADV
gsrj-10	171	27	when	when	SCONJ
gsrj-10	171	28	stressors	stressor	NOUN
gsrj-10	171	29	are	be	AUX
gsrj-10	171	30	involved	involve	VERB
gsrj-10	171	31	.	.	PUNCT
gsrj-10	172	1	it	it	PRON
gsrj-10	172	2	is	be	AUX
gsrj-10	172	3	imperative	imperative	ADJ
gsrj-10	172	4	that	that	SCONJ
gsrj-10	172	5	information	information	NOUN
gsrj-10	172	6	on	on	ADP
gsrj-10	172	7	these	these	DET
gsrj-10	172	8	dangers	danger	NOUN
gsrj-10	172	9	of	of	ADP
gsrj-10	172	10	nicotine	nicotine	NOUN
gsrj-10	172	11	becomes	become	VERB
gsrj-10	172	12	more	more	ADV
gsrj-10	172	13	widespread	widespread	ADJ
gsrj-10	172	14	so	so	SCONJ
gsrj-10	172	15	that	that	SCONJ
gsrj-10	172	16	society	society	NOUN
gsrj-10	172	17	will	will	AUX
gsrj-10	172	18	have	have	VERB
gsrj-10	172	19	a	a	DET
gsrj-10	172	20	comprehensive	comprehensive	ADJ
gsrj-10	172	21	understanding	understanding	NOUN
gsrj-10	172	22	of	of	ADP
gsrj-10	172	23	how	how	SCONJ
gsrj-10	172	24	consuming	consume	VERB
gsrj-10	172	25	nicotine	nicotine	NOUN
gsrj-10	172	26	can	can	AUX
gsrj-10	172	27	put	put	VERB
gsrj-10	172	28	people	people	NOUN
gsrj-10	172	29	at	at	ADP
gsrj-10	172	30	risk	risk	NOUN
gsrj-10	172	31	for	for	ADP
gsrj-10	172	32	adverse	adverse	ADJ
gsrj-10	172	33	behavioral	behavioral	ADJ
gsrj-10	172	34	disorders	disorder	NOUN
gsrj-10	172	35	,	,	PUNCT
gsrj-10	172	36	independent	independent	ADJ
gsrj-10	172	37	from	from	ADP
gsrj-10	172	38	addiction	addiction	NOUN
gsrj-10	172	39	.	.	PUNCT
gsrj-10	173	1	acknowledgments	acknowledgment	NOUN
gsrj-10	173	2	we	we	PRON
gsrj-10	173	3	would	would	AUX
gsrj-10	173	4	like	like	VERB
gsrj-10	173	5	to	to	PART
gsrj-10	173	6	acknowledge	acknowledge	VERB
gsrj-10	173	7	dr	dr	PROPN
gsrj-10	173	8	.	.	PROPN
gsrj-10	173	9	kathleen	kathleen	PROPN
gsrj-10	173	10	maguire	maguire	PROPN
gsrj-10	173	11	-	-	PUNCT
gsrj-10	173	12	zeiss	zeiss	PROPN
gsrj-10	173	13	for	for	ADP
gsrj-10	173	14	her	her	PRON
gsrj-10	173	15	guidance	guidance	NOUN
gsrj-10	173	16	and	and	CCONJ
gsrj-10	173	17	expertise	expertise	NOUN
gsrj-10	173	18	.	.	PUNCT
gsrj-10	174	1	references	reference	NOUN
gsrj-10	174	2	1	1	NUM
gsrj-10	174	3	.	.	PUNCT
gsrj-10	174	4	tobacco	tobacco	NOUN
gsrj-10	174	5	/	/	SYM
gsrj-10	174	6	nicotine	nicotine	NOUN
gsrj-10	174	7	and	and	CCONJ
gsrj-10	174	8	vaping	vaping	NOUN
gsrj-10	174	9	.	.	PUNCT
gsrj-10	175	1	national	national	PROPN
gsrj-10	175	2	insitute	insitute	PROPN
gsrj-10	175	3	of	of	ADP
gsrj-10	175	4	drug	drug	NOUN
gsrj-10	175	5	abuse	abuse	NOUN
gsrj-10	175	6	.	.	PUNCT
gsrj-10	176	1	[	[	X
gsrj-10	176	2	posting	post	VERB
gsrj-10	176	3	]	]	X
gsrj-10	176	4	.	.	PUNCT
gsrj-10	177	1	(	(	PUNCT
gsrj-10	177	2	2021	2021	NUM
gsrj-10	177	3	)	)	PUNCT
gsrj-10	177	4	.	.	PUNCT
gsrj-10	178	1	retrieved	retrieve	VERB
gsrj-10	178	2	from	from	ADP
gsrj-10	178	3	https://www.drugabuse.gov/drugsabuse/tobacconicotine-vaping	https://www.drugabuse.gov/drugsabuse/tobacconicotine-vaping	PROPN
gsrj-10	178	4	2	2	NUM
gsrj-10	178	5	.	.	PUNCT
gsrj-10	178	6	creamer	creamer	NOUN
gsrj-10	178	7	,	,	PUNCT
gsrj-10	178	8	m.	m.	PROPN
gsrj-10	178	9	r.	r.	PROPN
gsrj-10	178	10	,	,	PUNCT
gsrj-10	178	11	wang	wang	PROPN
gsrj-10	178	12	,	,	PUNCT
gsrj-10	178	13	t.	t.	PROPN
gsrj-10	178	14	w.	w.	PROPN
gsrj-10	178	15	,	,	PUNCT
gsrj-10	178	16	babb	babb	PROPN
gsrj-10	178	17	,	,	PUNCT
gsrj-10	178	18	s.	s.	PROPN
gsrj-10	178	19	,	,	PUNCT
gsrj-10	178	20	cullen	cullen	PROPN
gsrj-10	178	21	,	,	PUNCT
gsrj-10	178	22	k.	k.	PROPN
gsrj-10	178	23	a.	a.	PROPN
gsrj-10	178	24	,	,	PUNCT
gsrj-10	178	25	day	day	PROPN
gsrj-10	178	26	,	,	PUNCT
gsrj-10	178	27	h.	h.	PROPN
gsrj-10	178	28	,	,	PUNCT
gsrj-10	178	29	willis	willis	PROPN
gsrj-10	178	30	,	,	PUNCT
gsrj-10	178	31	g.	g.	PROPN
gsrj-10	178	32	,	,	PUNCT
gsrj-10	178	33	phd	phd	NOUN
gsrj-10	178	34	,	,	PUNCT
gsrj-10	178	35	…	…	PUNCT
gsrj-10	178	36	&	&	CCONJ
gsrj-10	178	37	neff	neff	PROPN
gsrj-10	178	38	,	,	PUNCT
gsrj-10	178	39	l.	l.	PROPN
gsrj-10	178	40	,	,	PUNCT
gsrj-10	178	41	phd	phd	PROPN
gsrj-10	178	42	.	.	PUNCT
gsrj-10	179	1	(	(	PUNCT
gsrj-10	179	2	2019	2019	NUM
gsrj-10	179	3	)	)	PUNCT
gsrj-10	179	4	.	.	PUNCT
gsrj-10	180	1	tobacco	tobacco	NOUN
gsrj-10	180	2	product	product	NOUN
gsrj-10	180	3	use	use	NOUN
gsrj-10	180	4	and	and	CCONJ
gsrj-10	180	5	cessation	cessation	NOUN
gsrj-10	180	6	indicators	indicator	NOUN
gsrj-10	180	7	among	among	ADP
gsrj-10	180	8	adults	adult	NOUN
gsrj-10	180	9	united	united	PROPN
gsrj-10	180	10	states	states	PROPN
gsrj-10	180	11	,	,	PUNCT
gsrj-10	180	12	2018	2018	NUM
gsrj-10	180	13	.	.	PUNCT
gsrj-10	181	1	http://dx.doi.org/10.15585/mmwr.mm6845a2	http://dx.doi.org/10.15585/mmwr.mm6845a2	NUM
gsrj-10	181	2	3	3	NUM
gsrj-10	181	3	.	.	X
gsrj-10	181	4	benowitz	benowitz	PROPN
gsrj-10	181	5	n.	n.	PROPN
gsrj-10	181	6	l.	l.	PROPN
gsrj-10	181	7	(	(	PUNCT
gsrj-10	181	8	2010	2010	NUM
gsrj-10	181	9	)	)	PUNCT
gsrj-10	181	10	.	.	PUNCT
gsrj-10	182	1	nicotine	nicotine	PROPN
gsrj-10	182	2	addiction	addiction	NOUN
gsrj-10	182	3	.	.	PUNCT
gsrj-10	183	1	the	the	DET
gsrj-10	183	2	new	new	PROPN
gsrj-10	183	3	england	england	PROPN
gsrj-10	183	4	journal	journal	PROPN
gsrj-10	183	5	of	of	ADP
gsrj-10	183	6	medicine	medicine	NOUN
gsrj-10	183	7	,	,	PUNCT
gsrj-10	183	8	362(24	362(24	NUM
gsrj-10	183	9	)	)	PUNCT
gsrj-10	183	10	,	,	PUNCT
gsrj-10	183	11	2295–2303	2295–2303	NUM
gsrj-10	183	12	.	.	PUNCT
gsrj-10	184	1	https://doi.org/10.1056/nejmra0809890	https://doi.org/10.1056/nejmra0809890	VERB
gsrj-10	184	2	4	4	NUM
gsrj-10	184	3	.	.	PUNCT
gsrj-10	185	1	mathew	mathew	PROPN
gsrj-10	185	2	,	,	PUNCT
gsrj-10	185	3	a.	a.	PROPN
gsrj-10	185	4	r.	r.	PROPN
gsrj-10	185	5	,	,	PUNCT
gsrj-10	185	6	hogarth	hogarth	NOUN
gsrj-10	185	7	,	,	PUNCT
gsrj-10	185	8	l.	l.	PROPN
gsrj-10	185	9	,	,	PUNCT
gsrj-10	185	10	leventhal	leventhal	PROPN
gsrj-10	185	11	,	,	PUNCT
gsrj-10	185	12	a.	a.	NOUN
gsrj-10	185	13	m.	m.	NOUN
gsrj-10	185	14	,	,	PUNCT
gsrj-10	185	15	cook	cook	PROPN
gsrj-10	185	16	,	,	PUNCT
gsrj-10	185	17	j.	j.	PROPN
gsrj-10	185	18	w.	w.	PROPN
gsrj-10	185	19	,	,	PUNCT
gsrj-10	185	20	&	&	CCONJ
gsrj-10	185	21	hitsman	hitsman	PROPN
gsrj-10	185	22	,	,	PUNCT
gsrj-10	185	23	b.	b.	PROPN
gsrj-10	185	24	(	(	PUNCT
gsrj-10	185	25	2017	2017	NUM
gsrj-10	185	26	)	)	PUNCT
gsrj-10	185	27	.	.	PUNCT
gsrj-10	186	1	cigarette	cigarette	NOUN
gsrj-10	186	2	smoking	smoking	NOUN
gsrj-10	186	3	and	and	CCONJ
gsrj-10	186	4	depression	depression	NOUN
gsrj-10	186	5	comorbidity	comorbidity	NOUN
gsrj-10	186	6	:	:	PUNCT
gsrj-10	186	7	systematic	systematic	ADJ
gsrj-10	186	8	review	review	NOUN
gsrj-10	186	9	and	and	CCONJ
gsrj-10	186	10	proposed	propose	VERB
gsrj-10	186	11	theoretical	theoretical	ADJ
gsrj-10	186	12	model	model	NOUN
gsrj-10	186	13	.	.	PUNCT
gsrj-10	187	1	addiction	addiction	NOUN
gsrj-10	187	2	(	(	PUNCT
gsrj-10	187	3	abingdon	abingdon	PROPN
gsrj-10	187	4	,	,	PUNCT
gsrj-10	187	5	england	england	PROPN
gsrj-10	187	6	)	)	PUNCT
gsrj-10	187	7	,	,	PUNCT
gsrj-10	187	8	112(3	112(3	NUM
gsrj-10	187	9	)	)	PUNCT
gsrj-10	187	10	,	,	PUNCT
gsrj-10	187	11	401–412	401–412	NUM
gsrj-10	187	12	.	.	PUNCT
gsrj-10	188	1	https://doi.org/10.1111/add.13604	https://doi.org/10.1111/add.13604	NOUN
gsrj-10	188	2	5	5	NUM
gsrj-10	188	3	.	.	PUNCT
gsrj-10	188	4	morel	morel	PROPN
gsrj-10	188	5	,	,	PUNCT
gsrj-10	188	6	c.	c.	PROPN
gsrj-10	188	7	,	,	PUNCT
gsrj-10	188	8	fernandez	fernandez	PROPN
gsrj-10	188	9	,	,	PUNCT
gsrj-10	188	10	s.	s.	PROPN
gsrj-10	188	11	p.	p.	PROPN
gsrj-10	188	12	,	,	PUNCT
gsrj-10	188	13	pantouli	pantouli	PROPN
gsrj-10	188	14	,	,	PUNCT
gsrj-10	188	15	f.	f.	PROPN
gsrj-10	188	16	,	,	PUNCT
gsrj-10	188	17	meye	meye	NOUN
gsrj-10	188	18	,	,	PUNCT
gsrj-10	188	19	f.	f.	PROPN
gsrj-10	188	20	j.	j.	PROPN
gsrj-10	188	21	,	,	PUNCT
gsrj-10	188	22	marti	marti	PROPN
gsrj-10	188	23	,	,	PUNCT
gsrj-10	188	24	f.	f.	PROPN
gsrj-10	188	25	,	,	PUNCT
gsrj-10	188	26	tolu	tolu	PROPN
gsrj-10	188	27	,	,	PUNCT
gsrj-10	188	28	s.	s.	PROPN
gsrj-10	188	29	,	,	PUNCT
gsrj-10	188	30	…	…	PUNCT
gsrj-10	188	31	&	&	CCONJ
gsrj-10	188	32	moretti	moretti	PROPN
gsrj-10	188	33	,	,	PUNCT
gsrj-10	188	34	m.	m.	NOUN
gsrj-10	188	35	(	(	PUNCT
gsrj-10	188	36	2018	2018	NUM
gsrj-10	188	37	)	)	PUNCT
gsrj-10	188	38	.	.	PUNCT
gsrj-10	189	1	nicotinic	nicotinic	ADJ
gsrj-10	189	2	receptors	receptor	NOUN
gsrj-10	189	3	mediate	mediate	VERB
gsrj-10	189	4	stress	stress	NOUN
gsrj-10	189	5	-	-	PUNCT
gsrj-10	189	6	nicotine	nicotine	ADJ
gsrj-10	189	7	detrimental	detrimental	ADJ
gsrj-10	189	8	interplay	interplay	NOUN
gsrj-10	189	9	via	via	ADP
gsrj-10	189	10	dopamine	dopamine	NOUN
gsrj-10	189	11	cells	cell	NOUN
gsrj-10	189	12	’	'	PUNCT
gsrj-10	189	13	activity	activity	NOUN
gsrj-10	189	14	.	.	PUNCT
gsrj-10	190	1	molecular	molecular	ADJ
gsrj-10	190	2	psychiatry	psychiatry	NOUN
gsrj-10	190	3	,	,	PUNCT
gsrj-10	190	4	23(7	23(7	NUM
gsrj-10	190	5	)	)	PUNCT
gsrj-10	190	6	,	,	PUNCT
gsrj-10	190	7	1597	1597	NUM
gsrj-10	190	8	-	-	SYM
gsrj-10	190	9	1605	1605	NUM
gsrj-10	190	10	.	.	PUNCT
gsrj-10	191	1	https://doi.org/10.1038/mp.2017.145	https://doi.org/10.1038/mp.2017.145	NOUN
gsrj-10	191	2	6	6	X
gsrj-10	191	3	.	.	X
gsrj-10	192	1	wise	wise	ADJ
gsrj-10	192	2	ra	ra	PROPN
gsrj-10	192	3	(	(	PUNCT
gsrj-10	192	4	1998	1998	NUM
gsrj-10	192	5	):	):	PUNCT
gsrj-10	192	6	drug	drug	NOUN
gsrj-10	192	7	-	-	PUNCT
gsrj-10	192	8	activation	activation	NOUN
gsrj-10	192	9	of	of	ADP
gsrj-10	192	10	brain	brain	NOUN
gsrj-10	192	11	reward	reward	NOUN
gsrj-10	192	12	pathways	pathway	NOUN
gsrj-10	192	13	.	.	PUNCT
gsrj-10	193	1	drug	drug	NOUN
gsrj-10	193	2	alcohol	alcohol	PROPN
gsrj-10	193	3	dependence	dependence	NOUN
gsrj-10	193	4	51:13–22	51:13–22	PROPN
gsrj-10	193	5	.	.	PUNCT
gsrj-10	194	1	doi	doi	NOUN
gsrj-10	194	2	:	:	PUNCT
gsrj-10	194	3	10.1016	10.1016	NUM
gsrj-10	194	4	/	/	SYM
gsrj-10	194	5	s03768716(98)00063	s03768716(98)00063	PROPN
gsrj-10	194	6	-	-	PUNCT
gsrj-10	194	7	5	5	NUM
gsrj-10	194	8	7	7	NUM
gsrj-10	194	9	.	.	PUNCT
gsrj-10	195	1	tolu	tolu	PROPN
gsrj-10	195	2	,	,	PUNCT
gsrj-10	195	3	s.	s.	PROPN
gsrj-10	195	4	,	,	PUNCT
gsrj-10	195	5	eddine	eddine	PROPN
gsrj-10	195	6	,	,	PUNCT
gsrj-10	195	7	r.	r.	PROPN
gsrj-10	195	8	,	,	PUNCT
gsrj-10	195	9	marti	marti	PROPN
gsrj-10	195	10	,	,	PUNCT
gsrj-10	195	11	f.	f.	PROPN
gsrj-10	195	12	,	,	PUNCT
gsrj-10	195	13	david	david	PROPN
gsrj-10	195	14	,	,	PUNCT
gsrj-10	195	15	v.	v.	ADV
gsrj-10	195	16	,	,	PUNCT
gsrj-10	195	17	graupner	graupner	NOUN
gsrj-10	195	18	,	,	PUNCT
gsrj-10	195	19	m.	m.	NOUN
gsrj-10	195	20	,	,	PUNCT
gsrj-10	195	21	pons	pon	NOUN
gsrj-10	195	22	,	,	PUNCT
gsrj-10	195	23	s.	s.	PROPN
gsrj-10	195	24	,	,	PUNCT
gsrj-10	195	25	baudonnat	baudonnat	PROPN
gsrj-10	195	26	,	,	PUNCT
gsrj-10	195	27	…	…	PUNCT
gsrj-10	195	28	&	&	CCONJ
gsrj-10	195	29	maskos	maskos	PROPN
gsrj-10	195	30	,	,	PUNCT
gsrj-10	195	31	u.	u.	PROPN
gsrj-10	195	32	(	(	PUNCT
gsrj-10	195	33	2013	2013	NUM
gsrj-10	195	34	)	)	PUNCT
gsrj-10	195	35	.	.	PUNCT
gsrj-10	196	1	co	co	NOUN
gsrj-10	196	2	-	-	NOUN
gsrj-10	196	3	activation	activation	NOUN
gsrj-10	196	4	of	of	ADP
gsrj-10	196	5	vta	vta	PROPN
gsrj-10	196	6	da	da	PROPN
gsrj-10	196	7	and	and	CCONJ
gsrj-10	196	8	gaba	gaba	PROPN
gsrj-10	196	9	neurons	neuron	NOUN
gsrj-10	196	10	mediates	mediate	VERB
gsrj-10	196	11	nicotine	nicotine	VERB
gsrj-10	196	12	reinforcement	reinforcement	NOUN
gsrj-10	196	13	.	.	PUNCT
gsrj-10	197	1	molecular	molecular	ADJ
gsrj-10	197	2	psychiatry	psychiatry	NOUN
gsrj-10	197	3	,	,	PUNCT
gsrj-10	197	4	18	18	NUM
gsrj-10	197	5	(	(	PUNCT
gsrj-10	197	6	3	3	NUM
gsrj-10	197	7	)	)	PUNCT
gsrj-10	197	8	,	,	PUNCT
gsrj-10	197	9	382–393	382–393	NUM
gsrj-10	197	10	.	.	PUNCT
gsrj-10	198	1	https://doi.org/10.1038/mp.2012.83	https://doi.org/10.1038/mp.2012.83	NUM
gsrj-10	198	2	8	8	NUM
gsrj-10	198	3	.	.	PUNCT
gsrj-10	198	4	nestler	nestler	PROPN
gsrj-10	198	5	e.	e.	PROPN
gsrj-10	198	6	j.	j.	PROPN
gsrj-10	198	7	,	,	PUNCT
gsrj-10	198	8	&	&	CCONJ
gsrj-10	198	9	carlezon	carlezon	PROPN
gsrj-10	198	10	,	,	PUNCT
gsrj-10	198	11	w.	w.	PROPN
gsrj-10	198	12	a.	a.	PROPN
gsrj-10	198	13	,	,	PUNCT
gsrj-10	198	14	jr	jr	PROPN
gsrj-10	198	15	(	(	PUNCT
gsrj-10	198	16	2006	2006	NUM
gsrj-10	198	17	):	):	PUNCT
gsrj-10	198	18	the	the	DET
gsrj-10	198	19	mesolimbic	mesolimbic	ADJ
gsrj-10	198	20	dopamine	dopamine	NOUN
gsrj-10	198	21	reward	reward	NOUN
gsrj-10	198	22	circuit	circuit	NOUN
gsrj-10	198	23	in	in	ADP
gsrj-10	198	24	depression	depression	NOUN
gsrj-10	198	25	.	.	PUNCT
gsrj-10	199	1	biological	biological	ADJ
gsrj-10	199	2	psychiatry	psychiatry	NOUN
gsrj-10	199	3	,	,	PUNCT
gsrj-10	199	4	59	59	NUM
gsrj-10	199	5	(	(	PUNCT
gsrj-10	199	6	12	12	NUM
gsrj-10	199	7	)	)	PUNCT
gsrj-10	199	8	,	,	PUNCT
gsrj-10	199	9	11511159	11511159	NUM
gsrj-10	199	10	.	.	PUNCT
gsrj-10	200	1	https://doi.org/10.1016/j.biopsych.2005.09.01	https://doi.org/10.1016/j.biopsych.2005.09.01	PROPN
gsrj-10	200	2	8	8	NUM
gsrj-10	200	3	9	9	NUM
gsrj-10	200	4	.	.	PUNCT
gsrj-10	201	1	faure	faure	PROPN
gsrj-10	201	2	p	p	NOUN
gsrj-10	201	3	,	,	PUNCT
gsrj-10	201	4	tolu	tolu	PROPN
gsrj-10	201	5	s	s	PROPN
gsrj-10	201	6	,	,	PUNCT
gsrj-10	201	7	valverde	valverde	PROPN
gsrj-10	201	8	s	s	PROPN
gsrj-10	201	9	,	,	PUNCT
gsrj-10	201	10	naudé	naudé	PROPN
gsrj-10	201	11	j.	j.	PROPN
gsrj-10	201	12	(	(	PUNCT
gsrj-10	201	13	2014	2014	NUM
gsrj-10	201	14	)	)	PUNCT
gsrj-10	201	15	.	.	PUNCT
gsrj-10	202	1	role	role	NOUN
gsrj-10	202	2	of	of	ADP
gsrj-10	202	3	nicotinic	nicotinic	ADJ
gsrj-10	202	4	acetylcholine	acetylcholine	NOUN
gsrj-10	202	5	receptors	receptor	NOUN
gsrj-10	202	6	in	in	ADP
gsrj-10	202	7	regulating	regulate	VERB
gsrj-10	202	8	dopamine	dopamine	NOUN
gsrj-10	202	9	neuron	neuron	NOUN
gsrj-10	202	10	activity	activity	NOUN
gsrj-10	202	11	.	.	PUNCT
gsrj-10	203	1	81	81	NUM
gsrj-10	203	2	georgetown	georgetown	PROPN
gsrj-10	203	3	scientific	scientific	PROPN
gsrj-10	203	4	research	research	PROPN
gsrj-10	203	5	journal	journal	NOUN
gsrj-10	203	6	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	PROPN
gsrj-10	203	7	neuroscience	neuroscience	PROPN
gsrj-10	203	8	,	,	PUNCT
gsrj-10	203	9	282	282	NUM
gsrj-10	203	10	,	,	PUNCT
gsrj-10	203	11	86	86	NUM
gsrj-10	203	12	-	-	SYM
gsrj-10	203	13	100	100	NUM
gsrj-10	203	14	.	.	PUNCT
gsrj-10	204	1	https://doi.org/10.1016/j.neuroscience.2014.0	https://doi.org/10.1016/j.neuroscience.2014.0	NUM
gsrj-10	204	2	5.040	5.040	NUM
gsrj-10	204	3	10	10	NUM
gsrj-10	204	4	.	.	PUNCT
gsrj-10	205	1	mineur	mineur	PROPN
gsrj-10	205	2	y.	y.	PROPN
gsrj-10	205	3	s.	s.	PROPN
gsrj-10	205	4	,	,	PUNCT
gsrj-10	205	5	fote	fote	VERB
gsrj-10	205	6	,	,	PUNCT
gsrj-10	205	7	g.	g.	PROPN
gsrj-10	205	8	m.	m.	PROPN
gsrj-10	205	9	,	,	PUNCT
gsrj-10	205	10	blakeman	blakeman	PROPN
gsrj-10	205	11	,	,	PUNCT
gsrj-10	205	12	s.	s.	PROPN
gsrj-10	205	13	,	,	PUNCT
gsrj-10	205	14	cahuzac	cahuzac	PROPN
gsrj-10	205	15	e.	e.	PROPN
gsrj-10	205	16	l.	l.	PROPN
gsrj-10	205	17	,	,	PUNCT
gsrj-10	205	18	newbold	newbold	PROPN
gsrj-10	205	19	,	,	PUNCT
gsrj-10	205	20	s.	s.	PROPN
gsrj-10	205	21	a.	a.	PROPN
gsrj-10	205	22	,	,	PUNCT
gsrj-10	205	23	&	&	CCONJ
gsrj-10	205	24	picciotto	picciotto	NOUN
gsrj-10	205	25	,	,	PUNCT
gsrj-10	205	26	m.	m.	PROPN
gsrj-10	205	27	r.	r.	PROPN
gsrj-10	205	28	(	(	PUNCT
gsrj-10	205	29	2016	2016	NUM
gsrj-10	205	30	)	)	PUNCT
gsrj-10	205	31	.	.	PUNCT
gsrj-10	206	1	multiple	multiple	ADJ
gsrj-10	206	2	nicotinic	nicotinic	ADJ
gsrj-10	206	3	acetylcholine	acetylcholine	NOUN
gsrj-10	206	4	receptor	receptor	NOUN
gsrj-10	206	5	subtypes	subtype	NOUN
gsrj-10	206	6	in	in	ADP
gsrj-10	206	7	the	the	DET
gsrj-10	206	8	mouse	mouse	NOUN
gsrj-10	206	9	amygdala	amygdala	NOUN
gsrj-10	206	10	regulate	regulate	VERB
gsrj-10	206	11	affective	affective	ADJ
gsrj-10	206	12	behaviors	behavior	NOUN
gsrj-10	206	13	and	and	CCONJ
gsrj-10	206	14	response	response	NOUN
gsrj-10	206	15	to	to	ADP
gsrj-10	206	16	social	social	ADJ
gsrj-10	206	17	stress	stress	NOUN
gsrj-10	206	18	.	.	PUNCT
gsrj-10	207	1	neuropsychopharmacology	neuropsychopharmacology	PROPN
gsrj-10	207	2	,	,	PUNCT
gsrj-10	207	3	41(6	41(6	PROPN
gsrj-10	207	4	)	)	PUNCT
gsrj-10	207	5	,	,	PUNCT
gsrj-10	207	6	1579–1587	1579–1587	NUM
gsrj-10	207	7	.	.	PUNCT
gsrj-10	208	1	https://doi.org/10.1038/npp.2015.316	https://doi.org/10.1038/npp.2015.316	PROPN
gsrj-10	208	2	11	11	NUM
gsrj-10	208	3	.	.	PUNCT
gsrj-10	209	1	saal	saal	PROPN
gsrj-10	209	2	,	,	PUNCT
gsrj-10	209	3	d.	d.	PROPN
gsrj-10	209	4	,	,	PUNCT
gsrj-10	209	5	dong	dong	PROPN
gsrj-10	209	6	,	,	PUNCT
gsrj-10	209	7	y.	y.	PROPN
gsrj-10	209	8	,	,	PUNCT
gsrj-10	209	9	bonci	bonci	PROPN
gsrj-10	209	10	,	,	PUNCT
gsrj-10	209	11	a.	a.	PROPN
gsrj-10	209	12	,	,	PUNCT
gsrj-10	209	13	&	&	CCONJ
gsrj-10	209	14	malenka	malenka	PROPN
gsrj-10	209	15	,	,	PUNCT
gsrj-10	209	16	r.	r.	PROPN
gsrj-10	209	17	c.	c.	PROPN
gsrj-10	209	18	(	(	PUNCT
gsrj-10	209	19	2003	2003	NUM
gsrj-10	209	20	,	,	PUNCT
gsrj-10	209	21	february	february	PROPN
gsrj-10	209	22	20	20	NUM
gsrj-10	209	23	)	)	PUNCT
gsrj-10	209	24	.	.	PUNCT
gsrj-10	210	1	drugs	drug	NOUN
gsrj-10	210	2	of	of	ADP
gsrj-10	210	3	abuse	abuse	NOUN
gsrj-10	210	4	and	and	CCONJ
gsrj-10	210	5	stress	stress	NOUN
gsrj-10	210	6	trigger	trigger	NOUN
gsrj-10	210	7	a	a	DET
gsrj-10	210	8	common	common	ADJ
gsrj-10	210	9	synaptic	synaptic	ADJ
gsrj-10	210	10	adaptation	adaptation	NOUN
gsrj-10	210	11	in	in	ADP
gsrj-10	210	12	dopamine	dopamine	NOUN
gsrj-10	210	13	neurons	neuron	NOUN
gsrj-10	210	14	.	.	PUNCT
gsrj-10	211	1	neuron	neuron	PROPN
gsrj-10	211	2	,	,	PUNCT
gsrj-10	211	3	37	37	NUM
gsrj-10	211	4	(	(	PUNCT
gsrj-10	211	5	4	4	NUM
gsrj-10	211	6	)	)	PUNCT
gsrj-10	211	7	,	,	PUNCT
gsrj-10	211	8	577–582	577–582	NUM
gsrj-10	211	9	.	.	PUNCT
gsrj-10	211	10	https://doi.org/10.1016/s08966273(03)00021-7	https://doi.org/10.1016/s08966273(03)00021-7	PROPN
gsrj-10	211	11	12	12	NUM
gsrj-10	211	12	.	.	PUNCT
gsrj-10	212	1	niehaus	niehaus	PROPN
gsrj-10	212	2	,	,	PUNCT
gsrj-10	212	3	j.	j.	PROPN
gsrj-10	212	4	l.	l.	PROPN
gsrj-10	212	5	,	,	PUNCT
gsrj-10	212	6	murali	murali	PROPN
gsrj-10	212	7	,	,	PUNCT
gsrj-10	212	8	m.	m.	NOUN
gsrj-10	212	9	,	,	PUNCT
gsrj-10	212	10	&	&	CCONJ
gsrj-10	212	11	kauer	kauer	PROPN
gsrj-10	212	12	,	,	PUNCT
gsrj-10	212	13	j.	j.	PROPN
gsrj-10	212	14	a.	a.	PROPN
gsrj-10	212	15	(	(	PUNCT
gsrj-10	212	16	2010	2010	NUM
gsrj-10	212	17	)	)	PUNCT
gsrj-10	212	18	.	.	PUNCT
gsrj-10	213	1	drugs	drug	NOUN
gsrj-10	213	2	of	of	ADP
gsrj-10	213	3	abuse	abuse	NOUN
gsrj-10	213	4	and	and	CCONJ
gsrj-10	213	5	stress	stress	NOUN
gsrj-10	213	6	impair	impair	VERB
gsrj-10	213	7	ltp	ltp	PROPN
gsrj-10	213	8	at	at	ADP
gsrj-10	213	9	inhibitory	inhibitory	ADJ
gsrj-10	213	10	synapses	synapsis	NOUN
gsrj-10	213	11	in	in	ADP
gsrj-10	213	12	the	the	DET
gsrj-10	213	13	ventral	ventral	ADJ
gsrj-10	213	14	tegmental	tegmental	ADJ
gsrj-10	213	15	area	area	NOUN
gsrj-10	213	16	:	:	PUNCT
gsrj-10	213	17	drugs	drug	NOUN
gsrj-10	213	18	and	and	CCONJ
gsrj-10	213	19	stress	stress	NOUN
gsrj-10	213	20	block	block	NOUN
gsrj-10	213	21	ltpgaba	ltpgaba	NOUN
gsrj-10	213	22	.	.	PUNCT
gsrj-10	214	1	european	european	ADJ
gsrj-10	214	2	journal	journal	PROPN
gsrj-10	214	3	of	of	ADP
gsrj-10	214	4	neuroscience	neuroscience	NOUN
gsrj-10	214	5	,	,	PUNCT
gsrj-10	214	6	32(1	32(1	NUM
gsrj-10	214	7	)	)	PUNCT
gsrj-10	214	8	,	,	PUNCT
gsrj-10	214	9	108	108	NUM
gsrj-10	214	10	–	–	SYM
gsrj-10	214	11	117	117	NUM
gsrj-10	214	12	.	.	PUNCT
gsrj-10	214	13	https://doi.org/10.1111/j.14609568.2010.07256.x	https://doi.org/10.1111/j.14609568.2010.07256.x	PROPN
gsrj-10	215	1	13	13	NUM
gsrj-10	215	2	.	.	PUNCT
gsrj-10	216	1	purves	purve	NOUN
gsrj-10	216	2	,	,	PUNCT
gsrj-10	216	3	d.	d.	PROPN
gsrj-10	216	4	(	(	PUNCT
gsrj-10	216	5	ed	ed	NOUN
gsrj-10	216	6	.	.	PUNCT
gsrj-10	216	7	)	)	PUNCT
gsrj-10	216	8	.	.	PUNCT
gsrj-10	217	1	(	(	PUNCT
gsrj-10	217	2	2008	2008	NUM
gsrj-10	217	3	)	)	PUNCT
gsrj-10	217	4	.	.	PUNCT
gsrj-10	218	1	neuroscience(4th	neuroscience(4th	PROPN
gsrj-10	218	2	ed	ed	NOUN
gsrj-10	218	3	)	)	PUNCT
gsrj-10	218	4	.	.	PUNCT
gsrj-10	219	1	sinauer	sinauer	NOUN
gsrj-10	219	2	.	.	PUNCT
gsrj-10	220	1	14	14	NUM
gsrj-10	220	2	.	.	PUNCT
gsrj-10	221	1	mann	mann	PROPN
gsrj-10	221	2	,	,	PUNCT
gsrj-10	221	3	m.	m.	NOUN
gsrj-10	221	4	(	(	PUNCT
gsrj-10	221	5	n.d	n.d	PROPN
gsrj-10	221	6	.	.	PROPN
gsrj-10	221	7	)	)	PUNCT
gsrj-10	221	8	.	.	PUNCT
gsrj-10	222	1	chapter	chapter	NOUN
gsrj-10	222	2	18	18	NUM
gsrj-10	222	3	:	:	PUNCT
gsrj-10	222	4	learning	learning	NOUN
gsrj-10	222	5	and	and	CCONJ
gsrj-10	222	6	memory	memory	NOUN
gsrj-10	222	7	.	.	PUNCT
gsrj-10	223	1	the	the	DET
gsrj-10	223	2	nervous	nervous	ADJ
gsrj-10	223	3	system	system	NOUN
gsrj-10	223	4	in	in	ADP
gsrj-10	223	5	action	action	NOUN
gsrj-10	223	6	.	.	PUNCT
gsrj-10	224	1	http://michaeldmann.net/mann18.html	http://michaeldmann.net/mann18.html	VERB
gsrj-10	224	2	15	15	NUM
gsrj-10	224	3	.	.	PUNCT
gsrj-10	225	1	n2	n2	ADJ
gsrj-10	225	2	—	—	PUNCT
gsrj-10	225	3	nicotinic	nicotinic	ADJ
gsrj-10	225	4	receptors	receptor	NOUN
gsrj-10	225	5	.	.	PUNCT
gsrj-10	226	1	(	(	PUNCT
gsrj-10	226	2	n.d	n.d	PROPN
gsrj-10	226	3	.	.	PROPN
gsrj-10	226	4	)	)	PUNCT
gsrj-10	226	5	.	.	PUNCT
gsrj-10	227	1	university	university	NOUN
gsrj-10	227	2	of	of	ADP
gsrj-10	227	3	south	south	PROPN
gsrj-10	227	4	carolina	carolina	PROPN
gsrj-10	227	5	school	school	PROPN
gsrj-10	227	6	of	of	ADP
gsrj-10	227	7	pharmacology	pharmacology	NOUN
gsrj-10	227	8	.	.	PUNCT
gsrj-10	228	1	http://163.178.103.176/fisiologia/general/acti	http://163.178.103.176/fisiologia/general/acti	VERB
gsrj-10	228	2	v_bas_3	v_bas_3	X
gsrj-10	228	3	/	/	SYM
gsrj-10	228	4	n2_nicotinic.html	n2_nicotinic.html	ADJ
gsrj-10	228	5	16	16	NUM
gsrj-10	228	6	.	.	PUNCT
gsrj-10	229	1	mansvelder	mansvelder	PROPN
gsrj-10	229	2	,	,	PUNCT
gsrj-10	229	3	h.	h.	PROPN
gsrj-10	229	4	d.	d.	PROPN
gsrj-10	229	5	,	,	PUNCT
gsrj-10	229	6	&	&	CCONJ
gsrj-10	229	7	mcgehee	mcgehee	PROPN
gsrj-10	229	8	,	,	PUNCT
gsrj-10	229	9	d.	d.	PROPN
gsrj-10	229	10	s.	s.	PROPN
gsrj-10	229	11	(	(	PUNCT
gsrj-10	229	12	2000	2000	NUM
gsrj-10	229	13	)	)	PUNCT
gsrj-10	229	14	.	.	PUNCT
gsrj-10	230	1	long	long	ADJ
gsrj-10	230	2	-	-	PUNCT
gsrj-10	230	3	term	term	NOUN
gsrj-10	230	4	potentiation	potentiation	NOUN
gsrj-10	230	5	of	of	ADP
gsrj-10	230	6	excitatory	excitatory	NOUN
gsrj-10	230	7	inputs	input	NOUN
gsrj-10	230	8	to	to	PART
gsrj-10	230	9	brain	brain	NOUN
gsrj-10	230	10	reward	reward	NOUN
gsrj-10	230	11	areas	area	NOUN
gsrj-10	230	12	by	by	ADP
gsrj-10	230	13	nicotine	nicotine	PROPN
gsrj-10	230	14	.	.	PUNCT
gsrj-10	231	1	neuron	neuron	PROPN
gsrj-10	231	2	,	,	PUNCT
gsrj-10	231	3	27	27	NUM
gsrj-10	231	4	(	(	PUNCT
gsrj-10	231	5	2	2	NUM
gsrj-10	231	6	)	)	PUNCT
gsrj-10	231	7	,	,	PUNCT
gsrj-10	231	8	349–357	349–357	NUM
gsrj-10	231	9	.	.	PUNCT
gsrj-10	232	1	https://doi.org/10.1016/s08966273(00)00042-8	https://doi.org/10.1016/s08966273(00)00042-8	PROPN
gsrj-10	232	2	17	17	NUM
gsrj-10	232	3	.	.	PUNCT
gsrj-10	233	1	zweifel	zweifel	NOUN
gsrj-10	233	2	,	,	PUNCT
gsrj-10	233	3	l.	l.	PROPN
gsrj-10	233	4	s.	s.	PROPN
gsrj-10	233	5	,	,	PUNCT
gsrj-10	233	6	argilli	argilli	PROPN
gsrj-10	233	7	,	,	PUNCT
gsrj-10	233	8	e.	e.	PROPN
gsrj-10	233	9	,	,	PUNCT
gsrj-10	233	10	bonci	bonci	PROPN
gsrj-10	233	11	,	,	PUNCT
gsrj-10	233	12	a.	a.	PROPN
gsrj-10	233	13	,	,	PUNCT
gsrj-10	233	14	&	&	CCONJ
gsrj-10	233	15	palmiter	palmiter	PROPN
gsrj-10	233	16	,	,	PUNCT
gsrj-10	233	17	r.	r.	PROPN
gsrj-10	233	18	d.	d.	PROPN
gsrj-10	233	19	(	(	PUNCT
gsrj-10	233	20	2008	2008	NUM
gsrj-10	233	21	)	)	PUNCT
gsrj-10	233	22	.	.	PUNCT
gsrj-10	234	1	role	role	NOUN
gsrj-10	234	2	of	of	ADP
gsrj-10	234	3	nmda	nmda	ADJ
gsrj-10	234	4	receptors	receptor	NOUN
gsrj-10	234	5	in	in	ADP
gsrj-10	234	6	dopamine	dopamine	NOUN
gsrj-10	234	7	neurons	neuron	NOUN
gsrj-10	234	8	for	for	ADP
gsrj-10	234	9	plasticity	plasticity	NOUN
gsrj-10	234	10	and	and	CCONJ
gsrj-10	234	11	addictive	addictive	ADJ
gsrj-10	234	12	behaviors	behavior	NOUN
gsrj-10	234	13	.	.	PUNCT
gsrj-10	235	1	neuron	neuron	PROPN
gsrj-10	235	2	,	,	PUNCT
gsrj-10	235	3	59	59	NUM
gsrj-10	235	4	(	(	PUNCT
gsrj-10	235	5	3	3	NUM
gsrj-10	235	6	)	)	PUNCT
gsrj-10	235	7	,	,	PUNCT
gsrj-10	235	8	486	486	NUM
gsrj-10	235	9	–	–	PUNCT
gsrj-10	235	10	496	496	NUM
gsrj-10	235	11	.	.	PUNCT
gsrj-10	236	1	https://doi.org/10.1016/j.neuron.2008.05.028	https://doi.org/10.1016/j.neuron.2008.05.028	PROPN
gsrj-10	236	2	18	18	NUM
gsrj-10	236	3	.	.	PUNCT
gsrj-10	237	1	stelly	stelly	ADV
gsrj-10	237	2	,	,	PUNCT
gsrj-10	237	3	c.	c.	PROPN
gsrj-10	237	4	e.	e.	PROPN
gsrj-10	237	5	,	,	PUNCT
gsrj-10	237	6	pomrenze	pomrenze	PROPN
gsrj-10	237	7	,	,	PUNCT
gsrj-10	237	8	m.	m.	PROPN
gsrj-10	237	9	b.	b.	PROPN
gsrj-10	237	10	,	,	PUNCT
gsrj-10	237	11	cook	cook	VERB
gsrj-10	237	12	,	,	PUNCT
gsrj-10	237	13	j.	j.	PROPN
gsrj-10	237	14	b.	b.	PROPN
gsrj-10	237	15	,	,	PUNCT
gsrj-10	237	16	&	&	CCONJ
gsrj-10	237	17	morikawa	morikawa	PROPN
gsrj-10	237	18	,	,	PUNCT
gsrj-10	237	19	h.	h.	PROPN
gsrj-10	237	20	(	(	PUNCT
gsrj-10	237	21	2016	2016	NUM
gsrj-10	237	22	)	)	PUNCT
gsrj-10	237	23	.	.	PUNCT
gsrj-10	238	1	repeated	repeat	VERB
gsrj-10	238	2	social	social	ADJ
gsrj-10	238	3	defeat	defeat	NOUN
gsrj-10	238	4	stress	stress	NOUN
gsrj-10	238	5	enhances	enhance	VERB
gsrj-10	238	6	glutamatergic	glutamatergic	ADJ
gsrj-10	238	7	synaptic	synaptic	ADJ
gsrj-10	238	8	plasticity	plasticity	NOUN
gsrj-10	238	9	in	in	ADP
gsrj-10	238	10	the	the	DET
gsrj-10	238	11	vta	vta	PROPN
gsrj-10	238	12	and	and	CCONJ
gsrj-10	238	13	cocaine	cocaine	NOUN
gsrj-10	238	14	place	place	NOUN
gsrj-10	238	15	conditioning	conditioning	NOUN
gsrj-10	238	16	.	.	PUNCT
gsrj-10	239	1	elife	elife	NOUN
gsrj-10	239	2	,	,	PUNCT
gsrj-10	239	3	5	5	NUM
gsrj-10	239	4	,	,	PUNCT
gsrj-10	239	5	e15448	e15448	PROPN
gsrj-10	239	6	.	.	PUNCT
gsrj-10	239	7	https://doi.org/10.7554/elife.15448	https://doi.org/10.7554/elife.15448	PROPN
gsrj-10	240	1	19	19	NUM
gsrj-10	240	2	.	.	PUNCT
gsrj-10	240	3	joëls	joëls	PROPN
gsrj-10	240	4	,	,	PUNCT
gsrj-10	240	5	m.	m.	NOUN
gsrj-10	240	6	(	(	PUNCT
gsrj-10	240	7	2018	2018	NUM
gsrj-10	240	8	)	)	PUNCT
gsrj-10	240	9	.	.	PUNCT
gsrj-10	241	1	corticosteroids	corticosteroid	NOUN
gsrj-10	241	2	and	and	CCONJ
gsrj-10	241	3	the	the	DET
gsrj-10	241	4	brain	brain	NOUN
gsrj-10	241	5	.	.	PUNCT
gsrj-10	242	1	journal	journal	PROPN
gsrj-10	242	2	of	of	ADP
gsrj-10	242	3	endocrinology	endocrinology	NOUN
gsrj-10	242	4	,	,	PUNCT
gsrj-10	242	5	238(3	238(3	NUM
gsrj-10	242	6	)	)	PUNCT
gsrj-10	242	7	,	,	PUNCT
gsrj-10	242	8	r121	r121	PROPN
gsrj-10	242	9	–	–	PUNCT
gsrj-10	242	10	r130	r130	NUM
gsrj-10	242	11	.	.	PUNCT
gsrj-10	243	1	https://doi.org/10.1530/joe-18-0226	https://doi.org/10.1530/joe-18-0226	PRON
gsrj-10	243	2	20	20	NUM
gsrj-10	243	3	.	.	PUNCT
gsrj-10	243	4	barik	barik	PROPN
gsrj-10	243	5	,	,	PUNCT
gsrj-10	243	6	j.	j.	PROPN
gsrj-10	243	7	,	,	PUNCT
gsrj-10	243	8	marti	marti	PROPN
gsrj-10	243	9	,	,	PUNCT
gsrj-10	243	10	f.	f.	PROPN
gsrj-10	243	11	,	,	PUNCT
gsrj-10	243	12	morel	morel	PROPN
gsrj-10	243	13	,	,	PUNCT
gsrj-10	243	14	c.	c.	PROPN
gsrj-10	243	15	,	,	PUNCT
gsrj-10	243	16	fernandez	fernandez	PROPN
gsrj-10	243	17	,	,	PUNCT
gsrj-10	243	18	s.	s.	PROPN
gsrj-10	243	19	p.	p.	PROPN
gsrj-10	243	20	,	,	PUNCT
gsrj-10	243	21	lanteri	lanteri	PROPN
gsrj-10	243	22	,	,	PUNCT
gsrj-10	243	23	c.	c.	NOUN
gsrj-10	243	24	,	,	PUNCT
gsrj-10	243	25	godeheu	godeheu	PROPN
gsrj-10	243	26	,	,	PUNCT
gsrj-10	243	27	g.	g.	PROPN
gsrj-10	243	28	,	,	PUNCT
gsrj-10	243	29	tassin	tassin	PROPN
gsrj-10	243	30	,	,	PUNCT
gsrj-10	243	31	j.-p	j.-p	PROPN
gsrj-10	243	32	.	.	PROPN
gsrj-10	243	33	,	,	PUNCT
gsrj-10	243	34	mombereau	mombereau	PROPN
gsrj-10	243	35	,	,	PUNCT
gsrj-10	243	36	c.	c.	PROPN
gsrj-10	243	37	,	,	PUNCT
gsrj-10	243	38	faure	faure	PROPN
gsrj-10	243	39	,	,	PUNCT
gsrj-10	243	40	p.	p.	PROPN
gsrj-10	243	41	,	,	PUNCT
gsrj-10	243	42	&	&	CCONJ
gsrj-10	243	43	tronche	tronche	PROPN
gsrj-10	243	44	,	,	PUNCT
gsrj-10	243	45	f.	f.	PROPN
gsrj-10	243	46	(	(	PUNCT
gsrj-10	243	47	2013	2013	NUM
gsrj-10	243	48	)	)	PUNCT
gsrj-10	243	49	.	.	PUNCT
gsrj-10	244	1	chronic	chronic	ADJ
gsrj-10	244	2	stress	stress	NOUN
gsrj-10	244	3	triggers	trigger	VERB
gsrj-10	244	4	social	social	ADJ
gsrj-10	244	5	aversion	aversion	NOUN
gsrj-10	244	6	via	via	ADP
gsrj-10	244	7	glucocorticoid	glucocorticoid	ADJ
gsrj-10	244	8	receptor	receptor	NOUN
gsrj-10	244	9	in	in	ADP
gsrj-10	244	10	dopaminoceptive	dopaminoceptive	ADJ
gsrj-10	244	11	neurons	neuron	NOUN
gsrj-10	244	12	.	.	PUNCT
gsrj-10	245	1	science	science	NOUN
gsrj-10	245	2	,	,	PUNCT
gsrj-10	245	3	339	339	NUM
gsrj-10	245	4	(	(	PUNCT
gsrj-10	245	5	6117	6117	NUM
gsrj-10	245	6	)	)	PUNCT
gsrj-10	245	7	,	,	PUNCT
gsrj-10	245	8	332–335	332–335	NUM
gsrj-10	245	9	.	.	PUNCT
gsrj-10	245	10	https://doi.org/10.1126/science.1226767	https://doi.org/10.1126/science.1226767	PROPN
gsrj-10	245	11	21	21	NUM
gsrj-10	245	12	.	.	PUNCT
gsrj-10	246	1	nugent	nugent	PROPN
gsrj-10	246	2	,	,	PUNCT
gsrj-10	246	3	f.	f.	PROPN
gsrj-10	246	4	s.	s.	PROPN
gsrj-10	246	5	,	,	PUNCT
gsrj-10	246	6	&	&	CCONJ
gsrj-10	246	7	kauer	kauer	PROPN
gsrj-10	246	8	,	,	PUNCT
gsrj-10	246	9	j.	j.	PROPN
gsrj-10	246	10	a.	a.	PROPN
gsrj-10	246	11	(	(	PUNCT
gsrj-10	246	12	2008	2008	NUM
gsrj-10	246	13	)	)	PUNCT
gsrj-10	246	14	.	.	PUNCT
gsrj-10	247	1	ltp	ltp	PROPN
gsrj-10	247	2	of	of	ADP
gsrj-10	247	3	gabaergic	gabaergic	ADJ
gsrj-10	247	4	synapses	synapsis	NOUN
gsrj-10	247	5	in	in	ADP
gsrj-10	247	6	the	the	DET
gsrj-10	247	7	ventral	ventral	ADJ
gsrj-10	247	8	tegmental	tegmental	ADJ
gsrj-10	247	9	area	area	NOUN
gsrj-10	247	10	and	and	CCONJ
gsrj-10	247	11	beyond	beyond	ADP
gsrj-10	247	12	:	:	PUNCT
gsrj-10	247	13	ltp	ltp	PROPN
gsrj-10	247	14	of	of	ADP
gsrj-10	247	15	gabaergic	gabaergic	ADJ
gsrj-10	247	16	synapses	synapsis	NOUN
gsrj-10	247	17	in	in	ADP
gsrj-10	247	18	the	the	DET
gsrj-10	247	19	ventral	ventral	ADJ
gsrj-10	247	20	tegmental	tegmental	ADJ
gsrj-10	247	21	area	area	NOUN
gsrj-10	247	22	and	and	CCONJ
gsrj-10	247	23	beyond	beyond	ADP
gsrj-10	247	24	.	.	PUNCT
gsrj-10	248	1	the	the	DET
gsrj-10	248	2	journal	journal	NOUN
gsrj-10	248	3	of	of	ADP
gsrj-10	248	4	physiology	physiology	NOUN
gsrj-10	248	5	,	,	PUNCT
gsrj-10	248	6	586	586	NUM
gsrj-10	248	7	(	(	PUNCT
gsrj-10	248	8	6	6	NUM
gsrj-10	248	9	)	)	PUNCT
gsrj-10	248	10	,	,	PUNCT
gsrj-10	248	11	1487–1493	1487–1493	NUM
gsrj-10	248	12	.	.	PUNCT
gsrj-10	249	1	https://doi.org/10.1113/jphysiol.2007.148098	https://doi.org/10.1113/jphysiol.2007.148098	PROPN
gsrj-10	249	2	22	22	NUM
gsrj-10	249	3	.	.	PUNCT
gsrj-10	250	1	karan	karan	PROPN
gsrj-10	250	2	govindpani	govindpani	PROPN
gsrj-10	250	3	,	,	PUNCT
gsrj-10	250	4	beatriz	beatriz	PROPN
gsrj-10	250	5	calvo	calvo	PROPN
gsrj-10	250	6	-	-	PUNCT
gsrj-10	250	7	flores	flores	PROPN
gsrj-10	250	8	guzmán	guzmán	PROPN
gsrj-10	250	9	,	,	PUNCT
gsrj-10	250	10	chitra	chitra	PROPN
gsrj-10	250	11	vinnakota	vinnakota	PROPN
gsrj-10	250	12	,	,	PUNCT
gsrj-10	250	13	henry	henry	PROPN
gsrj-10	250	14	waldvogel	waldvogel	ADV
gsrj-10	250	15	,	,	PUNCT
gsrj-10	250	16	richard	richard	PROPN
gsrj-10	250	17	faull	faull	PROPN
gsrj-10	250	18	,	,	PUNCT
gsrj-10	250	19	&	&	CCONJ
gsrj-10	250	20	andrea	andrea	PROPN
gsrj-10	250	21	kwakowsky	kwakowsky	PROPN
gsrj-10	250	22	.	.	PUNCT
gsrj-10	251	1	(	(	PUNCT
gsrj-10	251	2	2017	2017	NUM
gsrj-10	251	3	)	)	PUNCT
gsrj-10	251	4	.	.	PUNCT
gsrj-10	252	1	towards	towards	ADP
gsrj-10	252	2	a	a	DET
gsrj-10	252	3	better	well	ADJ
gsrj-10	252	4	understanding	understanding	NOUN
gsrj-10	252	5	of	of	ADP
gsrj-10	252	6	gabaergic	gabaergic	ADJ
gsrj-10	252	7	remodeling	remodeling	NOUN
gsrj-10	252	8	in	in	ADP
gsrj-10	252	9	alzheimer	alzheimer	PROPN
gsrj-10	252	10	’s	’s	PART
gsrj-10	252	11	disease	disease	NOUN
gsrj-10	252	12	.	.	PUNCT
gsrj-10	253	1	international	international	ADJ
gsrj-10	253	2	journal	journal	NOUN
gsrj-10	253	3	of	of	ADP
gsrj-10	253	4	molecular	molecular	ADJ
gsrj-10	253	5	sciences	science	NOUN
gsrj-10	253	6	,	,	PUNCT
gsrj-10	253	7	18(8	18(8	NUM
gsrj-10	253	8	)	)	PUNCT
gsrj-10	253	9	,	,	PUNCT
gsrj-10	253	10	1813	1813	NUM
gsrj-10	253	11	.	.	PUNCT
gsrj-10	254	1	https://doi.org/10.3390/ijms18081813	https://doi.org/10.3390/ijms18081813	PROPN
gsrj-10	254	2	23	23	NUM
gsrj-10	254	3	.	.	PUNCT
gsrj-10	255	1	bouarab	bouarab	PROPN
gsrj-10	255	2	,	,	PUNCT
gsrj-10	255	3	c.	c.	PROPN
gsrj-10	255	4	,	,	PUNCT
gsrj-10	255	5	thompson	thompson	PROPN
gsrj-10	255	6	,	,	PUNCT
gsrj-10	255	7	b.	b.	PROPN
gsrj-10	255	8	,	,	PUNCT
gsrj-10	255	9	&	&	CCONJ
gsrj-10	255	10	polter	polter	PROPN
gsrj-10	255	11	,	,	PUNCT
gsrj-10	255	12	a.	a.	NOUN
gsrj-10	255	13	m.	m.	NOUN
gsrj-10	255	14	(	(	PUNCT
gsrj-10	255	15	2019	2019	NUM
gsrj-10	255	16	)	)	PUNCT
gsrj-10	255	17	.	.	PUNCT
gsrj-10	256	1	vta	vta	PROPN
gsrj-10	256	2	gaba	gaba	PROPN
gsrj-10	256	3	neurons	neuron	NOUN
gsrj-10	256	4	at	at	ADP
gsrj-10	256	5	the	the	DET
gsrj-10	256	6	interface	interface	NOUN
gsrj-10	256	7	of	of	ADP
gsrj-10	256	8	stress	stress	NOUN
gsrj-10	256	9	and	and	CCONJ
gsrj-10	256	10	reward	reward	NOUN
gsrj-10	256	11	.	.	PUNCT
gsrj-10	257	1	frontiers	frontier	NOUN
gsrj-10	257	2	in	in	ADP
gsrj-10	257	3	neural	neural	ADJ
gsrj-10	257	4	82	82	NUM
gsrj-10	257	5	georgetown	georgetown	PROPN
gsrj-10	257	6	scientific	scientific	PROPN
gsrj-10	257	7	research	research	PROPN
gsrj-10	257	8	journal	journal	NOUN
gsrj-10	257	9	https://doi.org/10.48091/suvn5250	https://doi.org/10.48091/suvn5250	ADJ
gsrj-10	257	10	circuits	circuit	NOUN
gsrj-10	257	11	,	,	PUNCT
gsrj-10	257	12	13	13	NUM
gsrj-10	257	13	,	,	PUNCT
gsrj-10	257	14	78	78	NUM
gsrj-10	257	15	.	.	PUNCT
gsrj-10	258	1	https://doi.org/10.3389/fncir.2019.00078	https://doi.org/10.3389/fncir.2019.00078	PROPN
gsrj-10	258	2	24	24	NUM
gsrj-10	258	3	.	.	PUNCT
gsrj-10	259	1	chaudhury	chaudhury	PROPN
gsrj-10	259	2	,	,	PUNCT
gsrj-10	259	3	d.	d.	PROPN
gsrj-10	259	4	,	,	PUNCT
gsrj-10	259	5	walsh	walsh	PROPN
gsrj-10	259	6	,	,	PUNCT
gsrj-10	259	7	j.	j.	PROPN
gsrj-10	259	8	,	,	PUNCT
gsrj-10	259	9	friedman	friedman	PROPN
gsrj-10	259	10	,	,	PUNCT
gsrj-10	259	11	a.	a.	PROPN
gsrj-10	259	12	,	,	PUNCT
gsrj-10	259	13	juarez	juarez	PROPN
gsrj-10	259	14	,	,	PUNCT
gsrj-10	259	15	b.	b.	PROPN
gsrj-10	259	16	,	,	PUNCT
gsrj-10	259	17	ku	ku	PROPN
gsrj-10	259	18	,	,	PUNCT
gsrj-10	259	19	s.	s.	PROPN
gsrj-10	259	20	m.	m.	PROPN
gsrj-10	259	21	,	,	PUNCT
gsrj-10	259	22	koo	koo	PROPN
gsrj-10	259	23	,	,	PUNCT
gsrj-10	259	24	j.	j.	PROPN
gsrj-10	259	25	w.	w.	PROPN
gsrj-10	259	26	,	,	PUNCT
gsrj-10	259	27	…	…	PUNCT
gsrj-10	259	28	&	&	CCONJ
gsrj-10	259	29	han	han	PROPN
gsrj-10	259	30	,	,	PUNCT
gsrj-10	259	31	m.	m.	NOUN
gsrj-10	259	32	(	(	PUNCT
gsrj-10	259	33	2013	2013	NUM
gsrj-10	259	34	)	)	PUNCT
gsrj-10	259	35	.	.	PUNCT
gsrj-10	260	1	rapid	rapid	ADJ
gsrj-10	260	2	regulation	regulation	NOUN
gsrj-10	260	3	of	of	ADP
gsrj-10	260	4	depressionrelated	depressionrelate	VERB
gsrj-10	260	5	behaviours	behaviour	NOUN
gsrj-10	260	6	by	by	ADP
gsrj-10	260	7	control	control	NOUN
gsrj-10	260	8	of	of	ADP
gsrj-10	260	9	midbrain	midbrain	NOUN
gsrj-10	260	10	dopamine	dopamine	NOUN
gsrj-10	260	11	neurons	neuron	NOUN
gsrj-10	260	12	.	.	PUNCT
gsrj-10	261	1	nature	nature	NOUN
gsrj-10	261	2	,	,	PUNCT
gsrj-10	261	3	493	493	NUM
gsrj-10	261	4	,	,	PUNCT
gsrj-10	261	5	532–536	532–536	NUM
gsrj-10	261	6	.	.	PUNCT
gsrj-10	262	1	https://doi.org/10.1038/nature11713	https://doi.org/10.1038/nature11713	PROPN
gsrj-10	262	2	25	25	NUM
gsrj-10	262	3	.	.	PUNCT
gsrj-10	262	4	giacobbe	giacobbe	NOUN
gsrj-10	262	5	,	,	PUNCT
gsrj-10	262	6	p.	p.	NOUN
gsrj-10	262	7	,	,	PUNCT
gsrj-10	262	8	mayberg	mayberg	PROPN
gsrj-10	262	9	,	,	PUNCT
gsrj-10	262	10	h.	h.	PROPN
gsrj-10	262	11	s.	s.	PROPN
gsrj-10	262	12	,	,	PUNCT
gsrj-10	262	13	&	&	CCONJ
gsrj-10	262	14	lozano	lozano	PROPN
gsrj-10	262	15	,	,	PUNCT
gsrj-10	262	16	a.	a.	NOUN
gsrj-10	262	17	m.	m.	NOUN
gsrj-10	262	18	(	(	PUNCT
gsrj-10	262	19	2009	2009	NUM
gsrj-10	262	20	)	)	PUNCT
gsrj-10	262	21	.	.	PUNCT
gsrj-10	263	1	treatment	treatment	NOUN
gsrj-10	263	2	resistant	resistant	ADJ
gsrj-10	263	3	depression	depression	NOUN
gsrj-10	263	4	as	as	ADP
gsrj-10	263	5	a	a	DET
gsrj-10	263	6	failure	failure	NOUN
gsrj-10	263	7	of	of	ADP
gsrj-10	263	8	brain	brain	NOUN
gsrj-10	263	9	homeostatic	homeostatic	ADJ
gsrj-10	263	10	mechanisms	mechanism	NOUN
gsrj-10	263	11	:	:	PUNCT
gsrj-10	263	12	implications	implication	NOUN
gsrj-10	263	13	for	for	ADP
gsrj-10	263	14	deep	deep	ADJ
gsrj-10	263	15	brain	brain	NOUN
gsrj-10	263	16	stimulation	stimulation	NOUN
gsrj-10	263	17	.	.	PUNCT
gsrj-10	264	1	experimental	experimental	ADJ
gsrj-10	264	2	neurology	neurology	NOUN
gsrj-10	264	3	,	,	PUNCT
gsrj-10	264	4	219(1	219(1	NUM
gsrj-10	264	5	)	)	PUNCT
gsrj-10	264	6	,	,	PUNCT
gsrj-10	264	7	44	44	NUM
gsrj-10	264	8	-	-	SYM
gsrj-10	264	9	52	52	NUM
gsrj-10	264	10	.	.	PUNCT
gsrj-10	265	1	https://doi.org/10.1016/j.expneurol.2009.04.0	https://doi.org/10.1016/j.expneurol.2009.04.0	VERB
gsrj-10	265	2	28	28	NUM
gsrj-10	265	3	26	26	NUM
gsrj-10	265	4	.	.	PUNCT
gsrj-10	265	5	dandekar	dandekar	PROPN
gsrj-10	265	6	,	,	PUNCT
gsrj-10	265	7	m.	m.	PROPN
gsrj-10	265	8	p.	p.	PROPN
gsrj-10	265	9	,	,	PUNCT
gsrj-10	265	10	fenoy	fenoy	VERB
gsrj-10	265	11	,	,	PUNCT
gsrj-10	265	12	a.	a.	PROPN
gsrj-10	265	13	j.	j.	PROPN
gsrj-10	265	14	,	,	PUNCT
gsrj-10	265	15	carvalho	carvalho	PROPN
gsrj-10	265	16	,	,	PUNCT
gsrj-10	265	17	a.	a.	PROPN
gsrj-10	265	18	f.	f.	PROPN
gsrj-10	265	19	,	,	PUNCT
gsrj-10	265	20	soares	soares	PROPN
gsrj-10	265	21	,	,	PUNCT
gsrj-10	265	22	j.	j.	PROPN
gsrj-10	265	23	c.	c.	PROPN
gsrj-10	265	24	,	,	PUNCT
gsrj-10	265	25	&	&	CCONJ
gsrj-10	265	26	quevedo	quevedo	PROPN
gsrj-10	265	27	,	,	PUNCT
gsrj-10	265	28	j.	j.	PROPN
gsrj-10	265	29	(	(	PUNCT
gsrj-10	265	30	2018	2018	NUM
gsrj-10	265	31	)	)	PUNCT
gsrj-10	265	32	.	.	PUNCT
gsrj-10	266	1	deep	deep	ADJ
gsrj-10	266	2	brain	brain	NOUN
gsrj-10	266	3	stimulation	stimulation	NOUN
gsrj-10	266	4	for	for	ADP
gsrj-10	266	5	treatment	treatment	NOUN
gsrj-10	266	6	-	-	PUNCT
gsrj-10	266	7	resistant	resistant	ADJ
gsrj-10	266	8	depression	depression	NOUN
gsrj-10	266	9	:	:	PUNCT
gsrj-10	266	10	an	an	DET
gsrj-10	266	11	integrative	integrative	ADJ
gsrj-10	266	12	review	review	NOUN
gsrj-10	266	13	of	of	ADP
gsrj-10	266	14	preclinical	preclinical	ADJ
gsrj-10	266	15	and	and	CCONJ
gsrj-10	266	16	clinical	clinical	ADJ
gsrj-10	266	17	findings	finding	NOUN
gsrj-10	266	18	and	and	CCONJ
gsrj-10	266	19	translational	translational	ADJ
gsrj-10	266	20	implications	implication	NOUN
gsrj-10	266	21	.	.	PUNCT
gsrj-10	267	1	mol	mol	ADP
gsrj-10	267	2	psychiatry	psychiatry	NOUN
gsrj-10	267	3	,	,	PUNCT
gsrj-10	267	4	23	23	NUM
gsrj-10	267	5	,	,	PUNCT
gsrj-10	267	6	1094–1112	1094–1112	NUM
gsrj-10	267	7	.	.	PUNCT
gsrj-10	268	1	https://doi.org/10.1038/mp.2018.2	https://doi.org/10.1038/mp.2018.2	VERB
gsrj-10	268	2	27	27	NUM
gsrj-10	268	3	.	.	PUNCT
gsrj-10	269	1	the	the	DET
gsrj-10	269	2	brain	brain	NOUN
gsrj-10	269	3	from	from	ADP
gsrj-10	269	4	top	top	NOUN
gsrj-10	269	5	to	to	ADP
gsrj-10	269	6	bottom	bottom	NOUN
gsrj-10	269	7	:	:	PUNCT
gsrj-10	269	8	the	the	DET
gsrj-10	269	9	reward	reward	NOUN
gsrj-10	269	10	circuit	circuit	NOUN
gsrj-10	269	11	.	.	PUNCT
gsrj-10	270	1	mcgill	mcgill	PROPN
gsrj-10	270	2	university	university	PROPN
gsrj-10	270	3	.	.	PUNCT
gsrj-10	271	1	[	[	X
gsrj-10	271	2	web	web	NOUN
gsrj-10	271	3	site	site	NOUN
gsrj-10	271	4	]	]	PUNCT
gsrj-10	271	5	.	.	PUNCT
gsrj-10	272	1	retrieved	retrieve	VERB
gsrj-10	272	2	from	from	ADP
gsrj-10	272	3	https://thebrain.mcgill.ca/flash/i/i_03/i_03_cl/	https://thebrain.mcgill.ca/flash/i/i_03/i_03_cl/	NOUN
gsrj-10	272	4	i_03_cl_que	i_03_cl_que	X
gsrj-10	272	5	/	/	SYM
gsrj-10	272	6	i_03_cl_que.html	i_03_cl_que.html	PROPN
gsrj-10	272	7	28	28	NUM
gsrj-10	272	8	.	.	PUNCT
gsrj-10	273	1	eban	eban	PROPN
gsrj-10	273	2	-	-	PUNCT
gsrj-10	273	3	rothschild	rothschild	PROPN
gsrj-10	273	4	,	,	PUNCT
gsrj-10	273	5	a.	a.	NOUN
gsrj-10	273	6	,	,	PUNCT
gsrj-10	273	7	rothschild	rothschild	PROPN
gsrj-10	273	8	,	,	PUNCT
gsrj-10	273	9	g.	g.	PROPN
gsrj-10	273	10	,	,	PUNCT
gsrj-10	273	11	giardino	giardino	PROPN
gsrj-10	273	12	,	,	PUNCT
gsrj-10	273	13	w.	w.	PROPN
gsrj-10	273	14	j.	j.	PROPN
gsrj-10	273	15	,	,	PUNCT
gsrj-10	273	16	jones	jones	PROPN
gsrj-10	273	17	,	,	PUNCT
gsrj-10	273	18	j.	j.	PROPN
gsrj-10	273	19	r.	r.	PROPN
gsrj-10	273	20	,	,	PUNCT
gsrj-10	273	21	&	&	CCONJ
gsrj-10	273	22	de	de	PROPN
gsrj-10	273	23	lecea	lecea	PROPN
gsrj-10	273	24	,	,	PUNCT
gsrj-10	273	25	l.	l.	PROPN
gsrj-10	273	26	(	(	PUNCT
gsrj-10	273	27	2016	2016	NUM
gsrj-10	273	28	)	)	PUNCT
gsrj-10	273	29	.	.	PUNCT
gsrj-10	274	1	vta	vta	PROPN
gsrj-10	274	2	dopaminergic	dopaminergic	ADJ
gsrj-10	274	3	neurons	neuron	NOUN
gsrj-10	274	4	regulate	regulate	VERB
gsrj-10	274	5	ethologically	ethologically	ADV
gsrj-10	274	6	relevant	relevant	ADJ
gsrj-10	274	7	sleep	sleep	NOUN
gsrj-10	274	8	–	–	PUNCT
gsrj-10	274	9	wake	wake	VERB
gsrj-10	274	10	behaviors	behavior	NOUN
gsrj-10	274	11	.	.	PUNCT
gsrj-10	275	1	nature	nature	NOUN
gsrj-10	275	2	neuroscience	neuroscience	NOUN
gsrj-10	275	3	,	,	PUNCT
gsrj-10	275	4	19	19	NUM
gsrj-10	275	5	,	,	PUNCT
gsrj-10	275	6	1356–1366	1356–1366	NUM
gsrj-10	275	7	.	.	PUNCT
gsrj-10	276	1	https://doi.org/10.1038/nn.4377	https://doi.org/10.1038/nn.4377	ADP
gsrj-10	276	2	29	29	NUM
gsrj-10	276	3	.	.	PUNCT
gsrj-10	277	1	teens	teen	NOUN
gsrj-10	277	2	using	use	VERB
gsrj-10	277	3	vaping	vaping	NOUN
gsrj-10	277	4	devices	device	NOUN
gsrj-10	277	5	in	in	ADP
gsrj-10	277	6	record	record	NOUN
gsrj-10	277	7	numbers	number	NOUN
gsrj-10	277	8	.	.	PUNCT
gsrj-10	278	1	national	national	PROPN
gsrj-10	278	2	institutes	institutes	PROPN
gsrj-10	278	3	of	of	ADP
gsrj-10	278	4	health	health	NOUN
gsrj-10	278	5	.	.	PUNCT
gsrj-10	279	1	[	[	X
gsrj-10	279	2	news	news	NOUN
gsrj-10	279	3	release	release	NOUN
gsrj-10	279	4	]	]	PUNCT
gsrj-10	279	5	.	.	PUNCT
gsrj-10	280	1	(	(	PUNCT
gsrj-10	280	2	2018	2018	NUM
gsrj-10	280	3	)	)	PUNCT
gsrj-10	280	4	.	.	PUNCT
gsrj-10	281	1	retrieved	retrieve	VERB
gsrj-10	281	2	from	from	ADP
gsrj-10	281	3	https://www.nih.gov/news-events/newsreleases/teens-using-vaping-devices-recordnumbers	https://www.nih.gov/news-events/newsreleases/teens-using-vaping-devices-recordnumber	NOUN
gsrj-10	281	4	30	30	NUM
gsrj-10	281	5	.	.	PUNCT
gsrj-10	282	1	brett	brett	PROPN
gsrj-10	282	2	,	,	PUNCT
gsrj-10	282	3	e.	e.	PROPN
gsrj-10	282	4	i.	i.	PROPN
gsrj-10	282	5	,	,	PUNCT
gsrj-10	282	6	miller	miller	PROPN
gsrj-10	282	7	,	,	PUNCT
gsrj-10	282	8	m.	m.	PROPN
gsrj-10	282	9	b.	b.	PROPN
gsrj-10	282	10	,	,	PUNCT
gsrj-10	282	11	leavens	leaven	VERB
gsrj-10	282	12	,	,	PUNCT
gsrj-10	282	13	e.	e.	PROPN
gsrj-10	282	14	,	,	PUNCT
gsrj-10	282	15	lopez	lopez	PROPN
gsrj-10	282	16	,	,	PUNCT
gsrj-10	282	17	s.	s.	PROPN
gsrj-10	282	18	v.	v.	PROPN
gsrj-10	282	19	,	,	PUNCT
gsrj-10	282	20	wagener	wagener	NOUN
gsrj-10	282	21	,	,	PUNCT
gsrj-10	282	22	t.	t.	PROPN
gsrj-10	282	23	l.	l.	PROPN
gsrj-10	282	24	,	,	PUNCT
gsrj-10	282	25	&	&	CCONJ
gsrj-10	282	26	leffingwell	leffingwell	PROPN
gsrj-10	282	27	,	,	PUNCT
gsrj-10	282	28	t.	t.	PROPN
gsrj-10	282	29	r.	r.	PROPN
gsrj-10	282	30	(	(	PUNCT
gsrj-10	282	31	2019	2019	NUM
gsrj-10	282	32	)	)	PUNCT
gsrj-10	282	33	.	.	PUNCT
gsrj-10	283	1	electronic	electronic	ADJ
gsrj-10	283	2	cigarette	cigarette	NOUN
gsrj-10	283	3	use	use	NOUN
gsrj-10	283	4	and	and	CCONJ
gsrj-10	283	5	sleep	sleep	VERB
gsrj-10	283	6	health	health	NOUN
gsrj-10	283	7	in	in	ADP
gsrj-10	283	8	young	young	ADJ
gsrj-10	283	9	adults	adult	NOUN
gsrj-10	283	10	.	.	PUNCT
gsrj-10	284	1	journal	journal	NOUN
gsrj-10	284	2	of	of	ADP
gsrj-10	284	3	sleep	sleep	NOUN
gsrj-10	284	4	research	research	NOUN
gsrj-10	284	5	.	.	PUNCT
gsrj-10	285	1	https://doi.org/10.1111/jsr.12902	https://doi.org/10.1111/jsr.12902	PROPN
gsrj-10	285	2	31	31	NUM
gsrj-10	285	3	.	.	PUNCT
gsrj-10	286	1	youth	youth	NOUN
gsrj-10	286	2	and	and	CCONJ
gsrj-10	286	3	tobacco	tobacco	NOUN
gsrj-10	286	4	use	use	NOUN
gsrj-10	286	5	:	:	PUNCT
gsrj-10	286	6	youth	youth	NOUN
gsrj-10	286	7	use	use	NOUN
gsrj-10	286	8	of	of	ADP
gsrj-10	286	9	tobacco	tobacco	NOUN
gsrj-10	286	10	products	product	NOUN
gsrj-10	286	11	in	in	ADP
gsrj-10	286	12	any	any	DET
gsrj-10	286	13	form	form	NOUN
gsrj-10	286	14	is	be	AUX
gsrj-10	286	15	unsafe	unsafe	ADJ
gsrj-10	286	16	.	.	PUNCT
gsrj-10	287	1	centers	center	NOUN
gsrj-10	287	2	for	for	ADP
gsrj-10	287	3	disease	disease	NOUN
gsrj-10	287	4	control	control	NOUN
gsrj-10	287	5	and	and	CCONJ
gsrj-10	287	6	prevention	prevention	NOUN
gsrj-10	287	7	.	.	PUNCT
gsrj-10	288	1	[	[	X
gsrj-10	288	2	posting	post	VERB
gsrj-10	288	3	]	]	X
gsrj-10	288	4	.	.	PUNCT
gsrj-10	289	1	(	(	PUNCT
gsrj-10	289	2	2020	2020	NUM
gsrj-10	289	3	)	)	PUNCT
gsrj-10	289	4	.	.	PUNCT
gsrj-10	290	1	retrieved	retrieve	VERB
gsrj-10	290	2	from	from	ADP
gsrj-10	290	3	https://www.cdc.gov/tobacco/data_statistics/fa	https://www.cdc.gov/tobacco/data_statistics/fa	NOUN
gsrj-10	290	4	ct_sheets	ct_sheet	NOUN
gsrj-10	290	5	/	/	SYM
gsrj-10	290	6	youth_data	youth_data	NOUN
gsrj-10	290	7	/	/	SYM
gsrj-10	290	8	tobacco_use	tobacco_use	PROPN
gsrj-10	290	9	/	/	SYM
gsrj-10	290	10	index.htm	index.htm	X
gsrj-10	290	11	83	83	NUM
gsrj-10	290	12	biological	biological	ADJ
gsrj-10	290	13	and	and	CCONJ
gsrj-10	290	14	physical	physical	ADJ
gsrj-10	290	15	interactions	interaction	NOUN
gsrj-10	290	16	at	at	ADP
gsrj-10	290	17	local	local	ADJ
gsrj-10	290	18	ocean	ocean	NOUN
gsrj-10	290	19	scales	scale	NOUN
gsrj-10	290	20	:	:	PUNCT
gsrj-10	290	21	coupled	couple	VERB
gsrj-10	290	22	systems	system	NOUN
gsrj-10	290	23	determinants	determinant	NOUN
gsrj-10	290	24	of	of	ADP
gsrj-10	290	25	hepatocellular	hepatocellular	ADJ
gsrj-10	290	26	carcinoma	carcinoma	NOUN
gsrj-10	290	27	in	in	ADP
gsrj-10	290	28	the	the	DET
gsrj-10	290	29	united	united	PROPN
gsrj-10	290	30	states	states	PROPN
gsrj-10	290	31	:	:	PUNCT
gsrj-10	290	32	differences	difference	NOUN
gsrj-10	290	33	in	in	ADP
gsrj-10	290	34	risk	risk	NOUN
gsrj-10	290	35	factor	factor	NOUN
gsrj-10	290	36	and	and	CCONJ
gsrj-10	290	37	geneti	geneti	VERB
gsrj-10	290	38	the	the	DET
gsrj-10	290	39	preventative	preventative	ADJ
gsrj-10	290	40	and	and	CCONJ
gsrj-10	290	41	healing	healing	NOUN
gsrj-10	290	42	properties	property	NOUN
gsrj-10	290	43	of	of	ADP
gsrj-10	290	44	performing	perform	VERB
gsrj-10	290	45	arts	art	NOUN
gsrj-10	290	46	in	in	ADP
gsrj-10	290	47	female	female	ADJ
gsrj-10	290	48	genital	genital	ADJ
gsrj-10	290	49	mutilation	mutilation	NOUN
gsrj-10	290	50	policy	policy	NOUN
gsrj-10	290	51	brief	brief	NOUN
gsrj-10	290	52	:	:	PUNCT
gsrj-10	290	53	comparison	comparison	NOUN
gsrj-10	290	54	and	and	CCONJ
gsrj-10	290	55	recommendations	recommendation	NOUN
gsrj-10	290	56	for	for	ADP
gsrj-10	290	57	state	state	NOUN
gsrj-10	290	58	covid-19	covid-19	PROPN
gsrj-10	290	59	responses	response	NOUN
gsrj-10	290	60	of	of	ADP
gsrj-10	290	61	new	new	PROPN
gsrj-10	290	62	mexico	mexico	PROPN
gsrj-10	290	63	and	and	CCONJ
gsrj-10	290	64	utah	utah	PROPN
gsrj-10	290	65	interplay	interplay	NOUN
gsrj-10	290	66	of	of	ADP
gsrj-10	290	67	nicotine	nicotine	NOUN
gsrj-10	290	68	and	and	CCONJ
gsrj-10	290	69	social	social	ADJ
gsrj-10	290	70	stress	stress	NOUN
gsrj-10	290	71	mediate	mediate	VERB
gsrj-10	290	72	dopaminergic	dopaminergic	ADJ
gsrj-10	290	73	neuron	neuron	NOUN
gsrj-10	290	74	firing	fire	VERB
gsrj-10	290	75	in	in	ADP
gsrj-10	290	76	the	the	DET
gsrj-10	290	77	ventral	ventral	ADJ
gsrj-10	290	78	tegmental	tegmental	NOUN
gsrj-10	290	79	evaluating	evaluate	VERB
gsrj-10	290	80	the	the	DET
gsrj-10	290	81	efficacy	efficacy	NOUN
gsrj-10	290	82	of	of	ADP
gsrj-10	290	83	targeted	target	VERB
gsrj-10	290	84	inhibitor	inhibitor	NOUN
gsrj-10	290	85	therapeutics	therapeutic	NOUN
gsrj-10	290	86	for	for	ADP
gsrj-10	290	87	sonic	sonic	ADJ
gsrj-10	290	88	hedgehog	hedgehog	ADJ
gsrj-10	290	89	medulloblastoma	medulloblastoma	NOUN
gsrj-10	290	90	:	:	PUNCT
gsrj-10	290	91	signi	signi	ADJ
gsrj-10	290	92	refractory	refractory	NOUN
gsrj-10	290	93	epilepsy	epilepsy	NOUN
gsrj-10	290	94	:	:	PUNCT
gsrj-10	290	95	mechanisms	mechanism	NOUN
gsrj-10	290	96	of	of	ADP
gsrj-10	290	97	pharmacoresistance	pharmacoresistance	ADJ
gsrj-10	290	98	table	table	NOUN
gsrj-10	290	99	of	of	ADP
gsrj-10	290	100	contents	content	NOUN