id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
gs-3446	Aphkhazava, David; Sulashvili, Nodar; Tkemaladze, Jaba	Stem Cell Systems and Regeneration	2025	49	.pdf	application/pdf	17703	1053	32	This review explores the heterogeneity and regulatory mechanisms governing stem cells across potency states—pluripotent, multipotent, and unipotent—emphasizing dynamic transcriptional circuits involving core factors (OCT4, SOX2, NANOG) and signaling pathways (Wnt/β-catenin, Notch, Hedgehog). Keywords: regeneration, tissue self-renewal, stem cells, asymmetric division, signaling pathways, aging, cell division temp, CRISPR-Cas9, iPSCs Georgian Scientists/ქართველი მეცნიერები ტ. 7 N 1, 2025 272 Introduction Stem cell systems represent a cornerstone of modern biological and medical research due to their unique capacity for self-renewal and differentiation.	cache/gs-3446.pdf	txt/gs-3446.txt