id	sid	tid	token	lemma	pos
gs-3921	1	1	microsoft	microsoft	PROPN
gs-3921	1	2	word	word	NOUN
gs-3921	1	3	fullpdf07032025	fullpdf07032025	PROPN
gs-3921	1	4	georgian	georgian	ADJ
gs-3921	1	5	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	1	6	მეცნიერები	მეცნიერები	NOUN
gs-3921	1	7	ტ.	ტ.	VERB
gs-3921	1	8	7	7	NUM
gs-3921	1	9	n	n	PRON
gs-3921	1	10	3	3	NUM
gs-3921	1	11	,	,	PUNCT
gs-3921	1	12	2025	2025	NUM
gs-3921	1	13	217	217	NUM
gs-3921	1	14	georgian	georgian	PROPN
gs-3921	1	15	scientists	scientist	NOUN
gs-3921	1	16	ქართველი	ქართველი	ADJ
gs-3921	1	17	მეცნიერები	მეცნიერები	PROPN
gs-3921	1	18	vol	vol	NOUN
gs-3921	1	19	.	.	PUNCT
gs-3921	1	20	7	7	NUM
gs-3921	1	21	issue	issue	NOUN
gs-3921	1	22	3	3	NUM
gs-3921	1	23	,	,	PUNCT
gs-3921	1	24	2025	2025	NUM
gs-3921	1	25	https://doi.org/10.52340/gs.2025.07.03.15	https://doi.org/10.52340/gs.2025.07.03.15	PRON
gs-3921	1	26	the	the	DET
gs-3921	1	27	scientificic	scientificic	NOUN
gs-3921	1	28	talks	talk	NOUN
gs-3921	1	29	of	of	ADP
gs-3921	1	30	comprehensive	comprehensive	ADJ
gs-3921	1	31	analysis	analysis	NOUN
gs-3921	1	32	of	of	ADP
gs-3921	1	33	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	1	34	and	and	CCONJ
gs-3921	1	35	patient	patient	NOUN
gs-3921	1	36	-	-	PUNCT
gs-3921	1	37	centered	center	VERB
gs-3921	1	38	care	care	NOUN
gs-3921	1	39	approaches	approach	NOUN
gs-3921	1	40	on	on	ADP
gs-3921	1	41	medication	medication	NOUN
gs-3921	1	42	-	-	PUNCT
gs-3921	1	43	induced	induce	VERB
gs-3921	1	44	adverse	adverse	ADJ
gs-3921	1	45	effects	effect	NOUN
gs-3921	1	46	and	and	CCONJ
gs-3921	1	47	toxicities	toxicity	NOUN
gs-3921	1	48	,	,	PUNCT
gs-3921	1	49	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	1	50	challenges	challenge	NOUN
gs-3921	1	51	,	,	PUNCT
gs-3921	1	52	implicated	implicate	VERB
gs-3921	1	53	drugs	drug	NOUN
gs-3921	1	54	,	,	PUNCT
gs-3921	1	55	underlying	underlie	VERB
gs-3921	1	56	determinants	determinant	NOUN
gs-3921	1	57	of	of	ADP
gs-3921	1	58	risk	risk	NOUN
gs-3921	1	59	,	,	PUNCT
gs-3921	1	60	and	and	CCONJ
gs-3921	1	61	strategic	strategic	ADJ
gs-3921	1	62	approaches	approach	NOUN
gs-3921	1	63	to	to	ADP
gs-3921	1	64	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	1	65	management	management	NOUN
gs-3921	1	66	nodar	nodar	NOUN
gs-3921	1	67	sulashvili1	sulashvili1	PROPN
gs-3921	1	68	,	,	PUNCT
gs-3921	1	69	rupali	rupali	VERB
gs-3921	1	70	digambar	digambar	PROPN
gs-3921	1	71	jadhav2	jadhav2	PROPN
gs-3921	1	72	,	,	PUNCT
gs-3921	1	73	margarita	margarita	PROPN
gs-3921	1	74	beglaryan3	beglaryan3	PROPN
gs-3921	1	75	,	,	PUNCT
gs-3921	1	76	nana	nana	PROPN
gs-3921	1	77	gorgaslidze4	gorgaslidze4	PROPN
gs-3921	1	78	,	,	PUNCT
gs-3921	1	79	luiza	luiza	PROPN
gs-3921	1	80	gabunia5	gabunia5	PROPN
gs-3921	1	81	,	,	PUNCT
gs-3921	1	82	nato	nato	PROPN
gs-3921	1	83	alavidze6	alavidze6	PROPN
gs-3921	1	84	,	,	PUNCT
gs-3921	1	85	natia	natia	PROPN
gs-3921	1	86	kvizhinadze7	kvizhinadze7	PROPN
gs-3921	1	87	,	,	PUNCT
gs-3921	1	88	marika	marika	PROPN
gs-3921	1	89	sulashvili8	sulashvili8	PROPN
gs-3921	1	90	,	,	PUNCT
gs-3921	1	91	lela	lela	PROPN
gs-3921	1	92	grigolia9	grigolia9	PROPN
gs-3921	1	93	,	,	PUNCT
gs-3921	1	94	kakhaber	kakhaber	PROPN
gs-3921	1	95	robakidze10	robakidze10	PROPN
gs-3921	1	96	,	,	PUNCT
gs-3921	1	97	irine	irine	NOUN
gs-3921	1	98	zarnadze11	zarnadze11	PROPN
gs-3921	1	99	,	,	PUNCT
gs-3921	1	100	shalva	shalva	PROPN
gs-3921	1	101	(	(	PUNCT
gs-3921	1	102	davit	davit	NOUN
gs-3921	1	103	)	)	PUNCT
gs-3921	1	104	zarnadze12	zarnadze12	NOUN
gs-3921	1	105	1scientific	1scientific	NUM
gs-3921	1	106	supervisor	supervisor	NOUN
gs-3921	1	107	,	,	PUNCT
gs-3921	1	108	md	md	PROPN
gs-3921	1	109	,	,	PUNCT
gs-3921	1	110	phd	phd	NOUN
gs-3921	1	111	,	,	PUNCT
gs-3921	1	112	doctor	doctor	NOUN
gs-3921	1	113	of	of	ADP
gs-3921	1	114	pharmaceutical	pharmaceutical	ADJ
gs-3921	1	115	and	and	CCONJ
gs-3921	1	116	pharmacological	pharmacological	ADJ
gs-3921	1	117	sciences	science	NOUN
gs-3921	1	118	in	in	ADP
gs-3921	1	119	medicine	medicine	NOUN
gs-3921	1	120	,	,	PUNCT
gs-3921	1	121	invited	invite	VERB
gs-3921	1	122	lecturer	lecturer	NOUN
gs-3921	1	123	(	(	PUNCT
gs-3921	1	124	invited	invite	VERB
gs-3921	1	125	professor	professor	NOUN
gs-3921	1	126	)	)	PUNCT
gs-3921	1	127	of	of	ADP
gs-3921	1	128	scientific	scientific	ADJ
gs-3921	1	129	research	research	NOUN
gs-3921	1	130	-	-	PUNCT
gs-3921	1	131	skills	skill	NOUN
gs-3921	1	132	center	center	NOUN
gs-3921	1	133	at	at	ADP
gs-3921	1	134	tbilisi	tbilisi	PROPN
gs-3921	1	135	state	state	PROPN
gs-3921	1	136	medical	medical	PROPN
gs-3921	1	137	university	university	PROPN
gs-3921	1	138	;	;	PUNCT
gs-3921	1	139	professor	professor	NOUN
gs-3921	1	140	of	of	ADP
gs-3921	1	141	medical	medical	ADJ
gs-3921	1	142	and	and	CCONJ
gs-3921	1	143	clinical	clinical	ADJ
gs-3921	1	144	pharmacology	pharmacology	NOUN
gs-3921	1	145	of	of	ADP
gs-3921	1	146	international	international	ADJ
gs-3921	1	147	school	school	NOUN
gs-3921	1	148	of	of	ADP
gs-3921	1	149	medicine	medicine	NOUN
gs-3921	1	150	at	at	ADP
gs-3921	1	151	alte	alte	PROPN
gs-3921	1	152	university	university	PROPN
gs-3921	1	153	;	;	PUNCT
gs-3921	1	154	professor	professor	NOUN
gs-3921	1	155	of	of	ADP
gs-3921	1	156	pharmacology	pharmacology	NOUN
gs-3921	1	157	of	of	ADP
gs-3921	1	158	faculty	faculty	NOUN
gs-3921	1	159	of	of	ADP
gs-3921	1	160	medicine	medicine	NOUN
gs-3921	1	161	at	at	ADP
gs-3921	1	162	georgian	georgian	PROPN
gs-3921	1	163	national	national	PROPN
gs-3921	1	164	university	university	PROPN
gs-3921	1	165	seu	seu	NOUN
gs-3921	1	166	;	;	PUNCT
gs-3921	1	167	associate	associate	ADJ
gs-3921	1	168	affiliated	affiliate	VERB
gs-3921	1	169	professor	professor	NOUN
gs-3921	1	170	of	of	ADP
gs-3921	1	171	medical	medical	ADJ
gs-3921	1	172	pharmacology	pharmacology	NOUN
gs-3921	1	173	of	of	ADP
gs-3921	1	174	faculty	faculty	NOUN
gs-3921	1	175	of	of	ADP
gs-3921	1	176	medicine	medicine	NOUN
gs-3921	1	177	at	at	ADP
gs-3921	1	178	sulkhan	sulkhan	PROPN
gs-3921	1	179	-	-	PUNCT
gs-3921	1	180	saba	saba	PROPN
gs-3921	1	181	orbeliani	orbeliani	PROPN
gs-3921	1	182	university	university	PROPN
gs-3921	1	183	;	;	PUNCT
gs-3921	1	184	associate	associate	NOUN
gs-3921	1	185	professor	professor	NOUN
gs-3921	1	186	of	of	ADP
gs-3921	1	187	pharmacology	pharmacology	NOUN
gs-3921	1	188	of	of	ADP
gs-3921	1	189	pharmacy	pharmacy	NOUN
gs-3921	1	190	program	program	NOUN
gs-3921	1	191	at	at	ADP
gs-3921	1	192	shota	shota	PROPN
gs-3921	1	193	meskhia	meskhia	PROPN
gs-3921	1	194	zugdidi	zugdidi	PROPN
gs-3921	1	195	state	state	PROPN
gs-3921	1	196	university	university	PROPN
gs-3921	1	197	;	;	PUNCT
gs-3921	1	198	associate	associate	NOUN
gs-3921	1	199	professor	professor	NOUN
gs-3921	1	200	of	of	ADP
gs-3921	1	201	medical	medical	ADJ
gs-3921	1	202	pharmacology	pharmacology	NOUN
gs-3921	1	203	at	at	ADP
gs-3921	1	204	school	school	NOUN
gs-3921	1	205	of	of	ADP
gs-3921	1	206	medicine	medicine	NOUN
gs-3921	1	207	at	at	ADP
gs-3921	1	208	david	david	PROPN
gs-3921	1	209	aghmashenebeli	aghmashenebeli	PROPN
gs-3921	1	210	university	university	PROPN
gs-3921	1	211	of	of	ADP
gs-3921	1	212	georgia	georgia	PROPN
gs-3921	1	213	;	;	PUNCT
gs-3921	1	214	associate	associate	NOUN
gs-3921	1	215	professor	professor	NOUN
gs-3921	1	216	of	of	ADP
gs-3921	1	217	biochemistry	biochemistry	NOUN
gs-3921	1	218	and	and	CCONJ
gs-3921	1	219	pharmacology	pharmacology	NOUN
gs-3921	1	220	direction	direction	NOUN
gs-3921	1	221	of	of	ADP
gs-3921	1	222	school	school	NOUN
gs-3921	1	223	of	of	ADP
gs-3921	1	224	health	health	NOUN
gs-3921	1	225	sciences	science	NOUN
gs-3921	1	226	at	at	ADP
gs-3921	1	227	the	the	DET
gs-3921	1	228	university	university	PROPN
gs-3921	1	229	of	of	ADP
gs-3921	1	230	georgia	georgia	PROPN
gs-3921	1	231	;	;	PUNCT
gs-3921	1	232	associate	associate	NOUN
gs-3921	1	233	professor	professor	NOUN
gs-3921	1	234	of	of	ADP
gs-3921	1	235	pharmacology	pharmacology	NOUN
gs-3921	1	236	of	of	ADP
gs-3921	1	237	faculty	faculty	NOUN
gs-3921	1	238	of	of	ADP
gs-3921	1	239	medicine	medicine	NOUN
gs-3921	1	240	at	at	ADP
gs-3921	1	241	east	east	PROPN
gs-3921	1	242	european	european	PROPN
gs-3921	1	243	university	university	PROPN
gs-3921	1	244	;	;	PUNCT
gs-3921	1	245	associate	associate	NOUN
gs-3921	1	246	professor	professor	NOUN
gs-3921	1	247	of	of	ADP
gs-3921	1	248	pharmacology	pharmacology	NOUN
gs-3921	1	249	of	of	ADP
gs-3921	1	250	faculty	faculty	NOUN
gs-3921	1	251	of	of	ADP
gs-3921	1	252	dentistry	dentistry	NOUN
gs-3921	1	253	and	and	CCONJ
gs-3921	1	254	pharmacy	pharmacy	NOUN
gs-3921	1	255	at	at	ADP
gs-3921	1	256	tbilisi	tbilisi	ADJ
gs-3921	1	257	humanitarian	humanitarian	ADJ
gs-3921	1	258	teaching	teaching	NOUN
gs-3921	1	259	university	university	NOUN
gs-3921	1	260	;	;	PUNCT
gs-3921	1	261	tbilisi	tbilisi	PROPN
gs-3921	1	262	,	,	PUNCT
gs-3921	1	263	georgia	georgia	PROPN
gs-3921	1	264	;	;	PUNCT
gs-3921	1	265	researcher	researcher	NOUN
gs-3921	1	266	of	of	ADP
gs-3921	1	267	department	department	PROPN
gs-3921	1	268	of	of	ADP
gs-3921	1	269	pharmaceutical	pharmaceutical	ADJ
gs-3921	1	270	management	management	NOUN
gs-3921	1	271	of	of	ADP
gs-3921	1	272	yerevan	yerevan	PROPN
gs-3921	1	273	state	state	PROPN
gs-3921	1	274	medical	medical	PROPN
gs-3921	1	275	university	university	PROPN
gs-3921	1	276	after	after	ADP
gs-3921	1	277	mkhitar	mkhitar	NOUN
gs-3921	1	278	heratsi	heratsi	PROPN
gs-3921	1	279	,	,	PUNCT
gs-3921	1	280	yerevan	yerevan	PROPN
gs-3921	1	281	,	,	PUNCT
gs-3921	1	282	armenia	armenia	PROPN
gs-3921	1	283	.	.	PUNCT
gs-3921	2	1	orcid	orcid	PROPN
gs-3921	2	2	https://orcid.org/0000-0002-9005-8577	https://orcid.org/0000-0002-9005-8577	PROPN
gs-3921	2	3	e	e	NOUN
gs-3921	2	4	-	-	NOUN
gs-3921	2	5	mail	mail	NOUN
gs-3921	2	6	:	:	PUNCT
gs-3921	2	7	n.sulashvili@ug.edu.ge	n.sulashvili@ug.edu.ge	PROPN
gs-3921	2	8	2md	2md	NOUN
gs-3921	3	1	©	©	NOUN
gs-3921	3	2	,	,	PUNCT
gs-3921	3	3	12	12	NUM
gs-3921	3	4	-	-	PUNCT
gs-3921	3	5	th	th	NUM
gs-3921	3	6	semester	semester	NOUN
gs-3921	3	7	student	student	NOUN
gs-3921	3	8	of	of	ADP
gs-3921	3	9	md	md	PROPN
gs-3921	3	10	medical	medical	PROPN
gs-3921	3	11	doctor	doctor	NOUN
gs-3921	3	12	degree	degree	NOUN
gs-3921	3	13	student	student	NOUN
gs-3921	3	14	of	of	ADP
gs-3921	3	15	international	international	ADJ
gs-3921	3	16	school	school	NOUN
gs-3921	3	17	of	of	ADP
gs-3921	3	18	medicine	medicine	NOUN
gs-3921	3	19	at	at	ADP
gs-3921	3	20	alte	alte	PROPN
gs-3921	3	21	university	university	PROPN
gs-3921	3	22	;	;	PUNCT
gs-3921	3	23	tbilisi	tbilisi	PROPN
gs-3921	3	24	,	,	PUNCT
gs-3921	3	25	georgia	georgia	PROPN
gs-3921	3	26	;	;	PUNCT
gs-3921	3	27	3md	3md	NOUN
gs-3921	3	28	,	,	PUNCT
gs-3921	3	29	phd	phd	NOUN
gs-3921	3	30	,	,	PUNCT
gs-3921	3	31	doctor	doctor	NOUN
gs-3921	3	32	of	of	ADP
gs-3921	3	33	pharmaceutical	pharmaceutical	NOUN
gs-3921	3	34	sciences	science	NOUN
gs-3921	3	35	,	,	PUNCT
gs-3921	3	36	academician	academician	NOUN
gs-3921	3	37	,	,	PUNCT
gs-3921	3	38	professor	professor	NOUN
gs-3921	3	39	of	of	ADP
gs-3921	3	40	yerevan	yerevan	PROPN
gs-3921	3	41	state	state	PROPN
gs-3921	3	42	medical	medical	PROPN
gs-3921	3	43	university	university	PROPN
gs-3921	3	44	after	after	ADP
gs-3921	3	45	mkhitar	mkhitar	NOUN
gs-3921	3	46	heratsi	heratsi	PROPN
gs-3921	3	47	,	,	PUNCT
gs-3921	3	48	head	head	NOUN
gs-3921	3	49	of	of	ADP
gs-3921	3	50	the	the	DET
gs-3921	3	51	department	department	PROPN
gs-3921	3	52	of	of	ADP
gs-3921	3	53	pharmaceutical	pharmaceutical	NOUN
gs-3921	3	54	management	management	NOUN
gs-3921	3	55	,	,	PUNCT
gs-3921	3	56	president	president	NOUN
gs-3921	3	57	of	of	ADP
gs-3921	3	58	association	association	PROPN
gs-3921	3	59	phesa	phesa	PROPN
gs-3921	3	60	(	(	PUNCT
gs-3921	3	61	pharmacy	pharmacy	NOUN
gs-3921	3	62	and	and	CCONJ
gs-3921	3	63	pharmacology	pharmacology	NOUN
gs-3921	3	64	education	education	NOUN
gs-3921	3	65	and	and	CCONJ
gs-3921	3	66	science	science	NOUN
gs-3921	3	67	association	association	PROPN
gs-3921	3	68	)	)	PUNCT
gs-3921	3	69	,	,	PUNCT
gs-3921	3	70	yerevan	yerevan	PROPN
gs-3921	3	71	,	,	PUNCT
gs-3921	3	72	armenia	armenia	PROPN
gs-3921	3	73	;	;	PUNCT
gs-3921	3	74	https://orcid.org/0000-0003-3697-6390	https://orcid.org/0000-0003-3697-6390	PROPN
gs-3921	3	75	4md	4md	NOUN
gs-3921	3	76	,	,	PUNCT
gs-3921	3	77	phd	phd	NOUN
gs-3921	3	78	,	,	PUNCT
gs-3921	3	79	doctor	doctor	NOUN
gs-3921	3	80	of	of	ADP
gs-3921	3	81	pharmaceutical	pharmaceutical	NOUN
gs-3921	3	82	sciences	science	NOUN
gs-3921	3	83	,	,	PUNCT
gs-3921	3	84	academician	academician	NOUN
gs-3921	3	85	,	,	PUNCT
gs-3921	3	86	professor	professor	NOUN
gs-3921	3	87	of	of	ADP
gs-3921	3	88	tbilisi	tbilisi	PROPN
gs-3921	3	89	state	state	PROPN
gs-3921	3	90	medical	medical	PROPN
gs-3921	3	91	university	university	PROPN
gs-3921	3	92	,	,	PUNCT
gs-3921	3	93	head	head	NOUN
gs-3921	3	94	of	of	ADP
gs-3921	3	95	the	the	DET
gs-3921	3	96	department	department	NOUN
gs-3921	3	97	of	of	ADP
gs-3921	3	98	social	social	ADJ
gs-3921	3	99	and	and	CCONJ
gs-3921	3	100	clinical	clinical	ADJ
gs-3921	3	101	pharmacy	pharmacy	NOUN
gs-3921	3	102	,	,	PUNCT
gs-3921	3	103	tbilisi	tbilisi	PROPN
gs-3921	3	104	,	,	PUNCT
gs-3921	3	105	georgia	georgia	PROPN
gs-3921	3	106	.	.	PUNCT
gs-3921	4	1	https://orcid.org/0000-00024563-5224	https://orcid.org/0000-00024563-5224	PROPN
gs-3921	4	2	5md	5md	NOUN
gs-3921	4	3	,	,	PUNCT
gs-3921	4	4	phd	phd	NOUN
gs-3921	4	5	,	,	PUNCT
gs-3921	4	6	doctor	doctor	NOUN
gs-3921	4	7	of	of	ADP
gs-3921	4	8	medical	medical	ADJ
gs-3921	4	9	sciences	sciences	PROPN
gs-3921	4	10	,	,	PUNCT
gs-3921	4	11	professor	professor	NOUN
gs-3921	4	12	,	,	PUNCT
gs-3921	4	13	director	director	NOUN
gs-3921	4	14	of	of	ADP
gs-3921	4	15	the	the	DET
gs-3921	4	16	scientific	scientific	ADJ
gs-3921	4	17	research	research	NOUN
gs-3921	4	18	-	-	PUNCT
gs-3921	4	19	skills	skill	NOUN
gs-3921	4	20	center	center	NOUN
gs-3921	4	21	at	at	ADP
gs-3921	4	22	tbilisi	tbilisi	PROPN
gs-3921	4	23	state	state	PROPN
gs-3921	4	24	medical	medical	PROPN
gs-3921	4	25	university	university	PROPN
gs-3921	4	26	,	,	PUNCT
gs-3921	4	27	professor	professor	NOUN
gs-3921	4	28	,	,	PUNCT
gs-3921	4	29	head	head	NOUN
gs-3921	4	30	of	of	ADP
gs-3921	4	31	the	the	DET
gs-3921	4	32	department	department	PROPN
gs-3921	4	33	of	of	ADP
gs-3921	4	34	medical	medical	ADJ
gs-3921	4	35	and	and	CCONJ
gs-3921	4	36	clinical	clinical	ADJ
gs-3921	4	37	pharmacology	pharmacology	NOUN
gs-3921	4	38	at	at	ADP
gs-3921	4	39	tbilisi	tbilisi	PROPN
gs-3921	4	40	state	state	PROPN
gs-3921	4	41	medical	medical	PROPN
gs-3921	4	42	university	university	PROPN
gs-3921	4	43	,	,	PUNCT
gs-3921	4	44	clinical	clinical	ADJ
gs-3921	4	45	pharmacologist	pharmacologist	NOUN
gs-3921	4	46	of	of	ADP
gs-3921	4	47	the	the	DET
gs-3921	4	48	first	first	ADJ
gs-3921	4	49	university	university	NOUN
gs-3921	4	50	clinic	clinic	NOUN
gs-3921	4	51	of	of	ADP
gs-3921	4	52	tbilisi	tbilisi	PROPN
gs-3921	4	53	state	state	PROPN
gs-3921	4	54	medical	medical	PROPN
gs-3921	4	55	university	university	PROPN
gs-3921	4	56	,	,	PUNCT
gs-3921	4	57	tbilisi	tbilisi	PROPN
gs-3921	4	58	,	,	PUNCT
gs-3921	4	59	georgia	georgia	PROPN
gs-3921	4	60	https://orcid.org/0000-0003-0856-2684	https://orcid.org/0000-0003-0856-2684	PROPN
gs-3921	4	61	georgian	georgian	PROPN
gs-3921	4	62	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	4	63	მეცნიერები	მეცნიერები	NOUN
gs-3921	4	64	ტ.	ტ.	VERB
gs-3921	4	65	7	7	NUM
gs-3921	4	66	n	n	PRON
gs-3921	4	67	3	3	NUM
gs-3921	4	68	,	,	PUNCT
gs-3921	4	69	2025	2025	NUM
gs-3921	4	70	218	218	NUM
gs-3921	4	71	6md	6md	NOUN
gs-3921	4	72	,	,	PUNCT
gs-3921	4	73	phd	phd	NOUN
gs-3921	4	74	,	,	PUNCT
gs-3921	4	75	doctor	doctor	NOUN
gs-3921	4	76	of	of	ADP
gs-3921	4	77	pharmaceutical	pharmaceutical	NOUN
gs-3921	4	78	sciences	science	NOUN
gs-3921	4	79	,	,	PUNCT
gs-3921	4	80	professor	professor	NOUN
gs-3921	4	81	of	of	ADP
gs-3921	4	82	akaki	akaki	PROPN
gs-3921	4	83	tsereteli	tsereteli	PROPN
gs-3921	4	84	state	state	PROPN
gs-3921	4	85	university	university	PROPN
gs-3921	4	86	,	,	PUNCT
gs-3921	4	87	faculty	faculty	NOUN
gs-3921	4	88	of	of	ADP
gs-3921	4	89	medicine	medicine	NOUN
gs-3921	4	90	,	,	PUNCT
gs-3921	4	91	department	department	NOUN
gs-3921	4	92	of	of	ADP
gs-3921	4	93	pharmacy	pharmacy	NOUN
gs-3921	4	94	,	,	PUNCT
gs-3921	4	95	kutaisi	kutaisi	PROPN
gs-3921	4	96	,	,	PUNCT
gs-3921	4	97	georgia	georgia	PROPN
gs-3921	4	98	.	.	PUNCT
gs-3921	5	1	professor	professor	PROPN
gs-3921	5	2	,	,	PUNCT
gs-3921	5	3	dean	dean	PROPN
gs-3921	5	4	faculty	faculty	NOUN
gs-3921	5	5	of	of	ADP
gs-3921	5	6	medicine	medicine	NOUN
gs-3921	5	7	at	at	ADP
gs-3921	5	8	east	east	PROPN
gs-3921	5	9	european	european	PROPN
gs-3921	5	10	university	university	PROPN
gs-3921	5	11	,	,	PUNCT
gs-3921	5	12	tbilisi	tbilisi	PROPN
gs-3921	5	13	,	,	PUNCT
gs-3921	5	14	georgia	georgia	PROPN
gs-3921	5	15	.	.	PUNCT
gs-3921	6	1	https://orcid.org/0000-0001-6695-5924	https://orcid.org/0000-0001-6695-5924	PROPN
gs-3921	6	2	7md	7md	PROPN
gs-3921	6	3	,	,	PUNCT
gs-3921	6	4	phd	phd	NOUN
gs-3921	6	5	,	,	PUNCT
gs-3921	6	6	doctor	doctor	NOUN
gs-3921	6	7	of	of	ADP
gs-3921	6	8	pharmaceutical	pharmaceutical	NOUN
gs-3921	6	9	sciences	science	NOUN
gs-3921	6	10	,	,	PUNCT
gs-3921	6	11	professor	professor	NOUN
gs-3921	6	12	of	of	ADP
gs-3921	6	13	tbilisi	tbilisi	PROPN
gs-3921	6	14	state	state	PROPN
gs-3921	6	15	medical	medical	PROPN
gs-3921	6	16	university	university	PROPN
gs-3921	6	17	,	,	PUNCT
gs-3921	6	18	department	department	NOUN
gs-3921	6	19	of	of	ADP
gs-3921	6	20	social	social	ADJ
gs-3921	6	21	and	and	CCONJ
gs-3921	6	22	clinical	clinical	ADJ
gs-3921	6	23	pharmacy	pharmacy	NOUN
gs-3921	6	24	;	;	PUNCT
gs-3921	6	25	tbilisi	tbilisi	PROPN
gs-3921	6	26	,	,	PUNCT
gs-3921	6	27	georgia	georgia	PROPN
gs-3921	6	28	.	.	PUNCT
gs-3921	7	1	8md	8md	ADJ
gs-3921	7	2	,	,	PUNCT
gs-3921	7	3	doctor	doctor	NOUN
gs-3921	7	4	of	of	ADP
gs-3921	7	5	family	family	NOUN
gs-3921	7	6	medicine	medicine	NOUN
gs-3921	7	7	,	,	PUNCT
gs-3921	7	8	invited	invite	VERB
gs-3921	7	9	lecturer	lecturer	NOUN
gs-3921	7	10	of	of	ADP
gs-3921	7	11	tbilisi	tbilisi	PROPN
gs-3921	7	12	state	state	PROPN
gs-3921	7	13	medical	medical	PROPN
gs-3921	7	14	university	university	PROPN
gs-3921	7	15	,	,	PUNCT
gs-3921	7	16	department	department	NOUN
gs-3921	7	17	of	of	ADP
gs-3921	7	18	molecular	molecular	ADJ
gs-3921	7	19	and	and	CCONJ
gs-3921	7	20	medical	medical	ADJ
gs-3921	7	21	genetics	genetic	NOUN
gs-3921	7	22	,	,	PUNCT
gs-3921	7	23	invited	invite	VERB
gs-3921	7	24	lecturer	lecturer	NOUN
gs-3921	7	25	of	of	ADP
gs-3921	7	26	genetics	genetic	NOUN
gs-3921	7	27	and	and	CCONJ
gs-3921	7	28	molecular	molecular	ADJ
gs-3921	7	29	biology	biology	NOUN
gs-3921	7	30	of	of	ADP
gs-3921	7	31	international	international	ADJ
gs-3921	7	32	school	school	NOUN
gs-3921	7	33	of	of	ADP
gs-3921	7	34	medicine	medicine	NOUN
gs-3921	7	35	at	at	ADP
gs-3921	7	36	alte	alte	PROPN
gs-3921	7	37	university	university	PROPN
gs-3921	7	38	;	;	PUNCT
gs-3921	7	39	invited	invite	VERB
gs-3921	7	40	professor	professor	NOUN
gs-3921	7	41	of	of	ADP
gs-3921	7	42	biochemistry	biochemistry	NOUN
gs-3921	7	43	and	and	CCONJ
gs-3921	7	44	molecular	molecular	ADJ
gs-3921	7	45	and	and	CCONJ
gs-3921	7	46	medical	medical	ADJ
gs-3921	7	47	genetics	genetic	NOUN
gs-3921	7	48	at	at	ADP
gs-3921	7	49	the	the	DET
gs-3921	7	50	university	university	PROPN
gs-3921	7	51	of	of	ADP
gs-3921	7	52	georgia	georgia	PROPN
gs-3921	7	53	.	.	PUNCT
gs-3921	8	1	tbilisi	tbilisi	PROPN
gs-3921	8	2	,	,	PUNCT
gs-3921	8	3	georgia	georgia	PROPN
gs-3921	8	4	.	.	PUNCT
gs-3921	9	1	orcid	orcid	PROPN
gs-3921	9	2	https://orcid.org/0000-0002-6338-4262	https://orcid.org/0000-0002-6338-4262	PROPN
gs-3921	9	3	.	.	PUNCT
gs-3921	10	1	9md	9md	NOUN
gs-3921	10	2	,	,	PUNCT
gs-3921	10	3	phd	phd	NOUN
gs-3921	10	4	,	,	PUNCT
gs-3921	10	5	doctor	doctor	NOUN
gs-3921	10	6	of	of	ADP
gs-3921	10	7	medical	medical	ADJ
gs-3921	10	8	sciences	science	NOUN
gs-3921	10	9	,	,	PUNCT
gs-3921	10	10	professor	professor	NOUN
gs-3921	10	11	of	of	ADP
gs-3921	10	12	faculty	faculty	NOUN
gs-3921	10	13	of	of	ADP
gs-3921	10	14	medicine	medicine	NOUN
gs-3921	10	15	at	at	ADP
gs-3921	10	16	caucasus	caucasus	PROPN
gs-3921	10	17	international	international	PROPN
gs-3921	10	18	university	university	PROPN
gs-3921	10	19	;	;	PUNCT
gs-3921	10	20	tbilisi	tbilisi	PROPN
gs-3921	10	21	,	,	PUNCT
gs-3921	10	22	georgia	georgia	PROPN
gs-3921	10	23	;	;	PUNCT
gs-3921	10	24	10md	10md	NUM
gs-3921	10	25	,	,	PUNCT
gs-3921	10	26	phd	phd	NOUN
gs-3921	10	27	,	,	PUNCT
gs-3921	10	28	doctor	doctor	NOUN
gs-3921	10	29	of	of	ADP
gs-3921	10	30	medical	medical	ADJ
gs-3921	10	31	sciences	science	NOUN
gs-3921	10	32	,	,	PUNCT
gs-3921	10	33	academician	academician	NOUN
gs-3921	10	34	,	,	PUNCT
gs-3921	10	35	professor	professor	NOUN
gs-3921	10	36	of	of	ADP
gs-3921	10	37	faculty	faculty	NOUN
gs-3921	10	38	of	of	ADP
gs-3921	10	39	medicine	medicine	NOUN
gs-3921	10	40	at	at	ADP
gs-3921	10	41	caucasus	caucasus	PROPN
gs-3921	10	42	international	international	PROPN
gs-3921	10	43	university	university	PROPN
gs-3921	10	44	;	;	PUNCT
gs-3921	10	45	doctor	doctor	NOUN
gs-3921	10	46	-	-	PUNCT
gs-3921	10	47	professor	professor	NOUN
gs-3921	10	48	of	of	ADP
gs-3921	10	49	national	national	PROPN
gs-3921	10	50	health	health	PROPN
gs-3921	10	51	center	center	NOUN
gs-3921	10	52	named	name	VERB
gs-3921	10	53	after	after	ADP
gs-3921	10	54	academician	academician	PROPN
gs-3921	10	55	o.	o.	PROPN
gs-3921	10	56	gudushauri	gudushauri	PROPN
gs-3921	10	57	;	;	PUNCT
gs-3921	10	58	tbilisi	tbilisi	PROPN
gs-3921	10	59	,	,	PUNCT
gs-3921	10	60	georgia	georgia	PROPN
gs-3921	10	61	;	;	PUNCT
gs-3921	10	62	11md	11md	NUM
gs-3921	10	63	,	,	PUNCT
gs-3921	10	64	phd	phd	NOUN
gs-3921	10	65	,	,	PUNCT
gs-3921	10	66	doctor	doctor	NOUN
gs-3921	10	67	of	of	ADP
gs-3921	10	68	medical	medical	ADJ
gs-3921	10	69	sciences	science	NOUN
gs-3921	10	70	,	,	PUNCT
gs-3921	10	71	professor	professor	NOUN
gs-3921	10	72	of	of	ADP
gs-3921	10	73	tbilisi	tbilisi	PROPN
gs-3921	10	74	state	state	PROPN
gs-3921	10	75	medical	medical	PROPN
gs-3921	10	76	university	university	PROPN
gs-3921	10	77	,	,	PUNCT
gs-3921	10	78	department	department	NOUN
gs-3921	10	79	of	of	ADP
gs-3921	10	80	public	public	ADJ
gs-3921	10	81	health	health	NOUN
gs-3921	10	82	,	,	PUNCT
gs-3921	10	83	health	health	NOUN
gs-3921	10	84	care	care	NOUN
gs-3921	10	85	management	management	NOUN
gs-3921	10	86	,	,	PUNCT
gs-3921	10	87	policy	policy	NOUN
gs-3921	10	88	and	and	CCONJ
gs-3921	10	89	economy	economy	NOUN
gs-3921	10	90	,	,	PUNCT
gs-3921	10	91	tbilisi	tbilisi	PROPN
gs-3921	10	92	,	,	PUNCT
gs-3921	10	93	georgia	georgia	PROPN
gs-3921	10	94	.	.	PUNCT
gs-3921	11	1	12md	12md	ADJ
gs-3921	11	2	,	,	PUNCT
gs-3921	11	3	phd	phd	NOUN
gs-3921	11	4	,	,	PUNCT
gs-3921	11	5	doctor	doctor	NOUN
gs-3921	11	6	of	of	ADP
gs-3921	11	7	medical	medical	ADJ
gs-3921	11	8	sciences	science	NOUN
gs-3921	11	9	,	,	PUNCT
gs-3921	11	10	professor	professor	NOUN
gs-3921	11	11	of	of	ADP
gs-3921	11	12	tbilisi	tbilisi	PROPN
gs-3921	11	13	state	state	PROPN
gs-3921	11	14	medical	medical	PROPN
gs-3921	11	15	university	university	PROPN
gs-3921	11	16	,	,	PUNCT
gs-3921	11	17	dean	dean	NOUN
gs-3921	11	18	of	of	ADP
gs-3921	11	19	the	the	DET
gs-3921	11	20	faculty	faculty	NOUN
gs-3921	11	21	of	of	ADP
gs-3921	11	22	public	public	ADJ
gs-3921	11	23	health	health	NOUN
gs-3921	11	24	,	,	PUNCT
gs-3921	11	25	head	head	NOUN
gs-3921	11	26	of	of	ADP
gs-3921	11	27	the	the	DET
gs-3921	11	28	department	department	NOUN
gs-3921	11	29	of	of	ADP
gs-3921	11	30	nutrition	nutrition	NOUN
gs-3921	11	31	,	,	PUNCT
gs-3921	11	32	aging	age	VERB
gs-3921	11	33	medicine	medicine	NOUN
gs-3921	11	34	,	,	PUNCT
gs-3921	11	35	environmental	environmental	ADJ
gs-3921	11	36	and	and	CCONJ
gs-3921	11	37	occupational	occupational	ADJ
gs-3921	11	38	health	health	NOUN
gs-3921	11	39	,	,	PUNCT
gs-3921	11	40	tbilisi	tbilisi	PROPN
gs-3921	11	41	,	,	PUNCT
gs-3921	11	42	georgia	georgia	PROPN
gs-3921	11	43	.	.	PUNCT
gs-3921	12	1	corresponding	correspond	VERB
gs-3921	12	2	author	author	NOUN
gs-3921	12	3	:	:	PUNCT
gs-3921	12	4	dr	dr	PROPN
gs-3921	12	5	.	.	PROPN
gs-3921	12	6	professor	professor	PROPN
gs-3921	12	7	nodar	nodar	PROPN
gs-3921	12	8	sulashvili	sulashvili	PROPN
gs-3921	12	9	mail	mail	NOUN
gs-3921	12	10	:	:	PUNCT
gs-3921	12	11	n.sulashvili@ug.edu.ge	n.sulashvili@ug.edu.ge	NOUN
gs-3921	12	12	mob	mob	NOUN
gs-3921	12	13	:	:	PUNCT
gs-3921	13	1	+995	+995	ADJ
gs-3921	13	2	-	-	ADJ
gs-3921	13	3	597	597	NUM
gs-3921	13	4	-	-	PUNCT
gs-3921	13	5	12	12	NUM
gs-3921	13	6	-	-	PUNCT
gs-3921	13	7	17	17	NUM
gs-3921	13	8	-	-	SYM
gs-3921	13	9	28	28	NUM
gs-3921	13	10	abstract	abstract	NOUN
gs-3921	13	11	the	the	DET
gs-3921	13	12	integration	integration	NOUN
gs-3921	13	13	of	of	ADP
gs-3921	13	14	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	13	15	into	into	ADP
gs-3921	13	16	modern	modern	ADJ
gs-3921	13	17	clinical	clinical	ADJ
gs-3921	13	18	practice	practice	NOUN
gs-3921	13	19	has	have	AUX
gs-3921	13	20	revolutionized	revolutionize	VERB
gs-3921	13	21	the	the	DET
gs-3921	13	22	understanding	understanding	NOUN
gs-3921	13	23	of	of	ADP
gs-3921	13	24	medication	medication	NOUN
gs-3921	13	25	-	-	PUNCT
gs-3921	13	26	induced	induce	VERB
gs-3921	13	27	adverse	adverse	ADJ
gs-3921	13	28	effects	effect	NOUN
gs-3921	13	29	and	and	CCONJ
gs-3921	13	30	toxicities	toxicity	NOUN
gs-3921	13	31	,	,	PUNCT
gs-3921	13	32	enabling	enable	VERB
gs-3921	13	33	a	a	DET
gs-3921	13	34	shift	shift	NOUN
gs-3921	13	35	toward	toward	ADP
gs-3921	13	36	personalized	personalized	ADJ
gs-3921	13	37	medicine	medicine	NOUN
gs-3921	13	38	.	.	PUNCT
gs-3921	14	1	this	this	DET
gs-3921	14	2	comprehensive	comprehensive	ADJ
gs-3921	14	3	analysis	analysis	NOUN
gs-3921	14	4	explores	explore	VERB
gs-3921	14	5	the	the	DET
gs-3921	14	6	intricate	intricate	ADJ
gs-3921	14	7	interplay	interplay	NOUN
gs-3921	14	8	between	between	ADP
gs-3921	14	9	genetic	genetic	ADJ
gs-3921	14	10	variations	variation	NOUN
gs-3921	14	11	and	and	CCONJ
gs-3921	14	12	clinical	clinical	ADJ
gs-3921	14	13	outcomes	outcome	NOUN
gs-3921	14	14	associated	associate	VERB
gs-3921	14	15	with	with	ADP
gs-3921	14	16	adverse	adverse	ADJ
gs-3921	14	17	drug	drug	NOUN
gs-3921	14	18	reactions	reaction	NOUN
gs-3921	14	19	(	(	PUNCT
gs-3921	14	20	adrs	adrs	PROPN
gs-3921	14	21	)	)	PUNCT
gs-3921	14	22	,	,	PUNCT
gs-3921	14	23	particularly	particularly	ADV
gs-3921	14	24	focusing	focus	VERB
gs-3921	14	25	on	on	ADP
gs-3921	14	26	severe	severe	ADJ
gs-3921	14	27	and	and	CCONJ
gs-3921	14	28	unpredictable	unpredictable	ADJ
gs-3921	14	29	toxicities	toxicity	NOUN
gs-3921	14	30	that	that	PRON
gs-3921	14	31	significantly	significantly	ADV
gs-3921	14	32	compromise	compromise	VERB
gs-3921	14	33	therapeutic	therapeutic	ADJ
gs-3921	14	34	efficacy	efficacy	NOUN
gs-3921	14	35	and	and	CCONJ
gs-3921	14	36	patient	patient	ADJ
gs-3921	14	37	safety	safety	NOUN
gs-3921	14	38	.	.	PUNCT
gs-3921	15	1	the	the	DET
gs-3921	15	2	central	central	ADJ
gs-3921	15	3	premise	premise	NOUN
gs-3921	15	4	of	of	ADP
gs-3921	15	5	this	this	DET
gs-3921	15	6	discourse	discourse	NOUN
gs-3921	15	7	lies	lie	VERB
gs-3921	15	8	in	in	ADP
gs-3921	15	9	decoding	decode	VERB
gs-3921	15	10	how	how	SCONJ
gs-3921	15	11	interindividual	interindividual	ADJ
gs-3921	15	12	genetic	genetic	ADJ
gs-3921	15	13	differences	difference	NOUN
gs-3921	15	14	influence	influence	VERB
gs-3921	15	15	drug	drug	NOUN
gs-3921	15	16	metabolism	metabolism	NOUN
gs-3921	15	17	,	,	PUNCT
gs-3921	15	18	immune	immune	ADJ
gs-3921	15	19	responses	response	NOUN
gs-3921	15	20	,	,	PUNCT
gs-3921	15	21	and	and	CCONJ
gs-3921	15	22	receptor	receptor	NOUN
gs-3921	15	23	sensitivity	sensitivity	NOUN
gs-3921	15	24	,	,	PUNCT
gs-3921	15	25	which	which	PRON
gs-3921	15	26	collectively	collectively	ADV
gs-3921	15	27	contribute	contribute	VERB
gs-3921	15	28	to	to	ADP
gs-3921	15	29	variable	variable	ADJ
gs-3921	15	30	drug	drug	NOUN
gs-3921	15	31	responses	response	NOUN
gs-3921	15	32	and	and	CCONJ
gs-3921	15	33	susceptibility	susceptibility	NOUN
gs-3921	15	34	to	to	ADP
gs-3921	15	35	adverse	adverse	ADJ
gs-3921	15	36	effects	effect	NOUN
gs-3921	15	37	.	.	PUNCT
gs-3921	16	1	these	these	DET
gs-3921	16	2	responses	response	NOUN
gs-3921	16	3	,	,	PUNCT
gs-3921	16	4	when	when	SCONJ
gs-3921	16	5	coupled	couple	VERB
gs-3921	16	6	with	with	ADP
gs-3921	16	7	inadequate	inadequate	ADJ
gs-3921	16	8	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	16	9	systems	system	NOUN
gs-3921	16	10	and	and	CCONJ
gs-3921	16	11	a	a	DET
gs-3921	16	12	limited	limited	ADJ
gs-3921	16	13	understanding	understanding	NOUN
gs-3921	16	14	of	of	ADP
gs-3921	16	15	at	at	ADP
gs-3921	16	16	-	-	PUNCT
gs-3921	16	17	risk	risk	NOUN
gs-3921	16	18	populations	population	NOUN
gs-3921	16	19	,	,	PUNCT
gs-3921	16	20	pose	pose	VERB
gs-3921	16	21	a	a	DET
gs-3921	16	22	profound	profound	ADJ
gs-3921	16	23	challenge	challenge	NOUN
gs-3921	16	24	to	to	ADP
gs-3921	16	25	global	global	ADJ
gs-3921	16	26	public	public	ADJ
gs-3921	16	27	health	health	NOUN
gs-3921	16	28	and	and	CCONJ
gs-3921	16	29	regulatory	regulatory	ADJ
gs-3921	16	30	bodies	body	NOUN
gs-3921	16	31	tasked	task	VERB
gs-3921	16	32	with	with	ADP
gs-3921	16	33	ensuring	ensure	VERB
gs-3921	16	34	medication	medication	NOUN
gs-3921	16	35	safety	safety	NOUN
gs-3921	16	36	.	.	PUNCT
gs-3921	17	1	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	17	2	markers	marker	NOUN
gs-3921	17	3	,	,	PUNCT
gs-3921	17	4	such	such	ADJ
gs-3921	17	5	as	as	ADP
gs-3921	17	6	polymorphisms	polymorphism	NOUN
gs-3921	17	7	in	in	ADP
gs-3921	17	8	cytochrome	cytochrome	ADJ
gs-3921	17	9	p450	p450	NUM
gs-3921	17	10	enzymes	enzyme	NOUN
gs-3921	17	11	,	,	PUNCT
gs-3921	17	12	hla	hla	NOUN
gs-3921	17	13	alleles	allele	NOUN
gs-3921	17	14	,	,	PUNCT
gs-3921	17	15	drug	drug	NOUN
gs-3921	17	16	transporters	transporter	NOUN
gs-3921	17	17	,	,	PUNCT
gs-3921	17	18	and	and	CCONJ
gs-3921	17	19	metabolic	metabolic	NOUN
gs-3921	17	20	enzymes	enzyme	NOUN
gs-3921	17	21	,	,	PUNCT
gs-3921	17	22	have	have	AUX
gs-3921	17	23	emerged	emerge	VERB
gs-3921	17	24	as	as	ADP
gs-3921	17	25	critical	critical	ADJ
gs-3921	17	26	determinants	determinant	NOUN
gs-3921	17	27	of	of	ADP
gs-3921	17	28	drug	drug	NOUN
gs-3921	17	29	toxicity	toxicity	NOUN
gs-3921	17	30	and	and	CCONJ
gs-3921	17	31	efficacy	efficacy	NOUN
gs-3921	17	32	.	.	PUNCT
gs-3921	18	1	variants	variant	NOUN
gs-3921	18	2	such	such	ADJ
gs-3921	18	3	as	as	ADP
gs-3921	18	4	hla	hla	PROPN
gs-3921	18	5	-	-	PUNCT
gs-3921	18	6	b57:01	b57:01	PROPN
gs-3921	18	7	in	in	ADP
gs-3921	18	8	abacavir	abacavir	NOUN
gs-3921	18	9	hypersensitivity	hypersensitivity	NOUN
gs-3921	18	10	and	and	CCONJ
gs-3921	18	11	hla	hla	PROPN
gs-3921	18	12	-	-	PUNCT
gs-3921	18	13	b15:02	b15:02	PROPN
gs-3921	18	14	in	in	ADP
gs-3921	18	15	carbamazepine	carbamazepine	NOUN
gs-3921	18	16	-	-	PUNCT
gs-3921	18	17	induced	induce	VERB
gs-3921	18	18	stevens	stevens	PROPN
gs-3921	18	19	-	-	PUNCT
gs-3921	18	20	johnson	johnson	PROPN
gs-3921	18	21	syndrome	syndrome	PROPN
gs-3921	18	22	exemplify	exemplify	VERB
gs-3921	18	23	the	the	DET
gs-3921	18	24	predictive	predictive	ADJ
gs-3921	18	25	potential	potential	NOUN
gs-3921	18	26	of	of	ADP
gs-3921	18	27	genetic	genetic	ADJ
gs-3921	18	28	screening	screening	NOUN
gs-3921	18	29	in	in	ADP
gs-3921	18	30	minimizing	minimize	VERB
gs-3921	18	31	lifethreatening	lifethreatene	VERB
gs-3921	18	32	adrs	adr	NOUN
gs-3921	18	33	.	.	PUNCT
gs-3921	19	1	despite	despite	SCONJ
gs-3921	19	2	these	these	DET
gs-3921	19	3	scientific	scientific	ADJ
gs-3921	19	4	breakthroughs	breakthrough	NOUN
gs-3921	19	5	,	,	PUNCT
gs-3921	19	6	clinical	clinical	ADJ
gs-3921	19	7	implementation	implementation	NOUN
gs-3921	19	8	remains	remain	VERB
gs-3921	19	9	inconsistent	inconsistent	ADJ
gs-3921	19	10	due	due	ADJ
gs-3921	19	11	to	to	ADP
gs-3921	19	12	gaps	gap	NOUN
gs-3921	19	13	in	in	ADP
gs-3921	19	14	awareness	awareness	NOUN
gs-3921	19	15	,	,	PUNCT
gs-3921	19	16	limited	limited	ADJ
gs-3921	19	17	access	access	NOUN
gs-3921	19	18	to	to	ADP
gs-3921	19	19	genotyping	genotyping	NOUN
gs-3921	19	20	tools	tool	NOUN
gs-3921	19	21	,	,	PUNCT
gs-3921	19	22	and	and	CCONJ
gs-3921	19	23	the	the	DET
gs-3921	19	24	absence	absence	NOUN
gs-3921	19	25	of	of	ADP
gs-3921	19	26	standardized	standardized	ADJ
gs-3921	19	27	clinical	clinical	ADJ
gs-3921	19	28	decision	decision	NOUN
gs-3921	19	29	support	support	NOUN
gs-3921	19	30	systems	system	NOUN
gs-3921	19	31	.	.	PUNCT
gs-3921	20	1	the	the	DET
gs-3921	20	2	translation	translation	NOUN
gs-3921	20	3	of	of	ADP
gs-3921	20	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	20	5	data	datum	NOUN
gs-3921	20	6	georgian	georgian	PROPN
gs-3921	20	7	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	20	8	მეცნიერები	მეცნიერები	NOUN
gs-3921	20	9	ტ.	ტ.	VERB
gs-3921	20	10	7	7	NUM
gs-3921	20	11	n	n	PRON
gs-3921	20	12	3	3	NUM
gs-3921	20	13	,	,	PUNCT
gs-3921	20	14	2025	2025	NUM
gs-3921	20	15	219	219	NUM
gs-3921	20	16	into	into	ADP
gs-3921	20	17	actionable	actionable	ADJ
gs-3921	20	18	clinical	clinical	ADJ
gs-3921	20	19	strategies	strategy	NOUN
gs-3921	20	20	is	be	AUX
gs-3921	20	21	further	far	ADV
gs-3921	20	22	hindered	hinder	VERB
gs-3921	20	23	by	by	ADP
gs-3921	20	24	complex	complex	ADJ
gs-3921	20	25	gene	gene	NOUN
gs-3921	20	26	–	–	PUNCT
gs-3921	20	27	drug	drug	NOUN
gs-3921	20	28	–	–	PUNCT
gs-3921	20	29	environment	environment	NOUN
gs-3921	20	30	interactions	interaction	NOUN
gs-3921	20	31	,	,	PUNCT
gs-3921	20	32	which	which	DET
gs-3921	20	33	necessitate	necessitate	ADJ
gs-3921	20	34	robust	robust	ADJ
gs-3921	20	35	,	,	PUNCT
gs-3921	20	36	multidimensional	multidimensional	ADJ
gs-3921	20	37	frameworks	framework	NOUN
gs-3921	20	38	for	for	ADP
gs-3921	20	39	accurate	accurate	ADJ
gs-3921	20	40	risk	risk	NOUN
gs-3921	20	41	prediction	prediction	NOUN
gs-3921	20	42	.	.	PUNCT
gs-3921	21	1	in	in	ADP
gs-3921	21	2	addition	addition	NOUN
gs-3921	21	3	to	to	ADP
gs-3921	21	4	genetic	genetic	ADJ
gs-3921	21	5	predisposition	predisposition	NOUN
gs-3921	21	6	,	,	PUNCT
gs-3921	21	7	the	the	DET
gs-3921	21	8	clinical	clinical	ADJ
gs-3921	21	9	spectrum	spectrum	NOUN
gs-3921	21	10	of	of	ADP
gs-3921	21	11	medicationinduced	medicationinduce	VERB
gs-3921	21	12	toxicities	toxicity	NOUN
gs-3921	21	13	is	be	AUX
gs-3921	21	14	shaped	shape	VERB
gs-3921	21	15	by	by	ADP
gs-3921	21	16	multiple	multiple	ADJ
gs-3921	21	17	contextual	contextual	ADJ
gs-3921	21	18	risk	risk	NOUN
gs-3921	21	19	factors	factor	NOUN
gs-3921	21	20	,	,	PUNCT
gs-3921	21	21	including	include	VERB
gs-3921	21	22	age	age	NOUN
gs-3921	21	23	,	,	PUNCT
gs-3921	21	24	sex	sex	NOUN
gs-3921	21	25	,	,	PUNCT
gs-3921	21	26	comorbid	comorbid	NOUN
gs-3921	21	27	conditions	condition	NOUN
gs-3921	21	28	,	,	PUNCT
gs-3921	21	29	organ	organ	NOUN
gs-3921	21	30	function	function	NOUN
gs-3921	21	31	,	,	PUNCT
gs-3921	21	32	polypharmacy	polypharmacy	NOUN
gs-3921	21	33	,	,	PUNCT
gs-3921	21	34	nutritional	nutritional	ADJ
gs-3921	21	35	status	status	NOUN
gs-3921	21	36	,	,	PUNCT
gs-3921	21	37	and	and	CCONJ
gs-3921	21	38	drug	drug	NOUN
gs-3921	21	39	-	-	PUNCT
gs-3921	21	40	drug	drug	NOUN
gs-3921	21	41	or	or	CCONJ
gs-3921	21	42	drug	drug	NOUN
gs-3921	21	43	-	-	PUNCT
gs-3921	21	44	disease	disease	NOUN
gs-3921	21	45	interactions	interaction	NOUN
gs-3921	21	46	.	.	PUNCT
gs-3921	22	1	elderly	elderly	ADJ
gs-3921	22	2	populations	population	NOUN
gs-3921	22	3	,	,	PUNCT
gs-3921	22	4	pediatric	pediatric	ADJ
gs-3921	22	5	patients	patient	NOUN
gs-3921	22	6	,	,	PUNCT
gs-3921	22	7	and	and	CCONJ
gs-3921	22	8	individuals	individual	NOUN
gs-3921	22	9	with	with	ADP
gs-3921	22	10	hepatic	hepatic	ADJ
gs-3921	22	11	or	or	CCONJ
gs-3921	22	12	renal	renal	ADJ
gs-3921	22	13	impairment	impairment	NOUN
gs-3921	22	14	exhibit	exhibit	NOUN
gs-3921	22	15	altered	alter	VERB
gs-3921	22	16	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	22	17	and	and	CCONJ
gs-3921	22	18	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	22	19	,	,	PUNCT
gs-3921	22	20	which	which	PRON
gs-3921	22	21	amplify	amplify	VERB
gs-3921	22	22	the	the	DET
gs-3921	22	23	risk	risk	NOUN
gs-3921	22	24	of	of	ADP
gs-3921	22	25	dose	dose	NOUN
gs-3921	22	26	-	-	PUNCT
gs-3921	22	27	dependent	dependent	ADJ
gs-3921	22	28	and	and	CCONJ
gs-3921	22	29	idiosyncratic	idiosyncratic	ADJ
gs-3921	22	30	reactions	reaction	NOUN
gs-3921	22	31	.	.	PUNCT
gs-3921	23	1	these	these	DET
gs-3921	23	2	vulnerable	vulnerable	ADJ
gs-3921	23	3	subgroups	subgroup	NOUN
gs-3921	23	4	are	be	AUX
gs-3921	23	5	often	often	ADV
gs-3921	23	6	underrepresented	underrepresente	VERB
gs-3921	23	7	in	in	ADP
gs-3921	23	8	clinical	clinical	ADJ
gs-3921	23	9	trials	trial	NOUN
gs-3921	23	10	,	,	PUNCT
gs-3921	23	11	thereby	thereby	ADV
gs-3921	23	12	limiting	limit	VERB
gs-3921	23	13	the	the	DET
gs-3921	23	14	generalizability	generalizability	NOUN
gs-3921	23	15	of	of	ADP
gs-3921	23	16	safety	safety	NOUN
gs-3921	23	17	data	datum	NOUN
gs-3921	23	18	and	and	CCONJ
gs-3921	23	19	delaying	delay	VERB
gs-3921	23	20	the	the	DET
gs-3921	23	21	detection	detection	NOUN
gs-3921	23	22	of	of	ADP
gs-3921	23	23	rare	rare	ADJ
gs-3921	23	24	or	or	CCONJ
gs-3921	23	25	long	long	ADJ
gs-3921	23	26	-	-	PUNCT
gs-3921	23	27	term	term	NOUN
gs-3921	23	28	toxicities	toxicity	NOUN
gs-3921	23	29	.	.	PUNCT
gs-3921	24	1	moreover	moreover	ADV
gs-3921	24	2	,	,	PUNCT
gs-3921	24	3	the	the	DET
gs-3921	24	4	widespread	widespread	ADJ
gs-3921	24	5	off	off	ADP
gs-3921	24	6	-	-	PUNCT
gs-3921	24	7	label	label	NOUN
gs-3921	24	8	use	use	NOUN
gs-3921	24	9	of	of	ADP
gs-3921	24	10	medications	medication	NOUN
gs-3921	24	11	,	,	PUNCT
gs-3921	24	12	particularly	particularly	ADV
gs-3921	24	13	in	in	ADP
gs-3921	24	14	oncology	oncology	NOUN
gs-3921	24	15	,	,	PUNCT
gs-3921	24	16	psychiatry	psychiatry	NOUN
gs-3921	24	17	,	,	PUNCT
gs-3921	24	18	and	and	CCONJ
gs-3921	24	19	infectious	infectious	ADJ
gs-3921	24	20	disease	disease	NOUN
gs-3921	24	21	therapy	therapy	NOUN
gs-3921	24	22	,	,	PUNCT
gs-3921	24	23	contributes	contribute	VERB
gs-3921	24	24	to	to	ADP
gs-3921	24	25	unanticipated	unanticipated	ADJ
gs-3921	24	26	adverse	adverse	ADJ
gs-3921	24	27	events	event	NOUN
gs-3921	24	28	that	that	PRON
gs-3921	24	29	may	may	AUX
gs-3921	24	30	not	not	PART
gs-3921	24	31	be	be	AUX
gs-3921	24	32	captured	capture	VERB
gs-3921	24	33	in	in	ADP
gs-3921	24	34	pre	pre	ADJ
gs-3921	24	35	-	-	ADJ
gs-3921	24	36	approval	approval	ADJ
gs-3921	24	37	safety	safety	NOUN
gs-3921	24	38	assessments	assessment	NOUN
gs-3921	24	39	.	.	PUNCT
gs-3921	25	1	a	a	DET
gs-3921	25	2	significant	significant	ADJ
gs-3921	25	3	dimension	dimension	NOUN
gs-3921	25	4	of	of	ADP
gs-3921	25	5	this	this	DET
gs-3921	25	6	analysis	analysis	NOUN
gs-3921	25	7	pertains	pertain	VERB
gs-3921	25	8	to	to	ADP
gs-3921	25	9	the	the	DET
gs-3921	25	10	systemic	systemic	ADJ
gs-3921	25	11	challenges	challenge	NOUN
gs-3921	25	12	faced	face	VERB
gs-3921	25	13	by	by	ADP
gs-3921	25	14	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	25	15	programs	program	NOUN
gs-3921	25	16	in	in	ADP
gs-3921	25	17	identifying	identify	VERB
gs-3921	25	18	,	,	PUNCT
gs-3921	25	19	reporting	reporting	NOUN
gs-3921	25	20	,	,	PUNCT
gs-3921	25	21	and	and	CCONJ
gs-3921	25	22	managing	manage	VERB
gs-3921	25	23	medicationrelated	medicationrelate	VERB
gs-3921	25	24	toxicities	toxicity	NOUN
gs-3921	25	25	.	.	PUNCT
gs-3921	26	1	despite	despite	SCONJ
gs-3921	26	2	advancements	advancement	NOUN
gs-3921	26	3	in	in	ADP
gs-3921	26	4	digital	digital	ADJ
gs-3921	26	5	health	health	NOUN
gs-3921	26	6	technologies	technology	NOUN
gs-3921	26	7	and	and	CCONJ
gs-3921	26	8	electronic	electronic	ADJ
gs-3921	26	9	health	health	NOUN
gs-3921	26	10	records	record	NOUN
gs-3921	26	11	,	,	PUNCT
gs-3921	26	12	underreporting	underreporte	VERB
gs-3921	26	13	of	of	ADP
gs-3921	26	14	adrs	adrs	PROPN
gs-3921	26	15	remains	remain	VERB
gs-3921	26	16	a	a	DET
gs-3921	26	17	persistent	persistent	ADJ
gs-3921	26	18	obstacle	obstacle	NOUN
gs-3921	26	19	,	,	PUNCT
gs-3921	26	20	attributed	attribute	VERB
gs-3921	26	21	to	to	ADP
gs-3921	26	22	clinician	clinician	NOUN
gs-3921	26	23	workload	workload	NOUN
gs-3921	26	24	,	,	PUNCT
gs-3921	26	25	lack	lack	NOUN
gs-3921	26	26	of	of	ADP
gs-3921	26	27	training	training	NOUN
gs-3921	26	28	,	,	PUNCT
gs-3921	26	29	and	and	CCONJ
gs-3921	26	30	fear	fear	NOUN
gs-3921	26	31	of	of	ADP
gs-3921	26	32	legal	legal	ADJ
gs-3921	26	33	implications	implication	NOUN
gs-3921	26	34	.	.	PUNCT
gs-3921	27	1	many	many	ADJ
gs-3921	27	2	developing	develop	VERB
gs-3921	27	3	countries	country	NOUN
gs-3921	27	4	operate	operate	VERB
gs-3921	27	5	under	under	ADP
gs-3921	27	6	resource	resource	NOUN
gs-3921	27	7	-	-	PUNCT
gs-3921	27	8	constrained	constrain	VERB
gs-3921	27	9	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	27	10	infrastructures	infrastructure	NOUN
gs-3921	27	11	,	,	PUNCT
gs-3921	27	12	lacking	lack	VERB
gs-3921	27	13	the	the	DET
gs-3921	27	14	capacity	capacity	NOUN
gs-3921	27	15	for	for	ADP
gs-3921	27	16	active	active	ADJ
gs-3921	27	17	surveillance	surveillance	NOUN
gs-3921	27	18	,	,	PUNCT
gs-3921	27	19	real	real	ADJ
gs-3921	27	20	-	-	PUNCT
gs-3921	27	21	time	time	NOUN
gs-3921	27	22	data	datum	NOUN
gs-3921	27	23	integration	integration	NOUN
gs-3921	27	24	,	,	PUNCT
gs-3921	27	25	and	and	CCONJ
gs-3921	27	26	signal	signal	ADJ
gs-3921	27	27	detection	detection	NOUN
gs-3921	27	28	analytics	analytic	NOUN
gs-3921	27	29	.	.	PUNCT
gs-3921	28	1	this	this	DET
gs-3921	28	2	deficiency	deficiency	NOUN
gs-3921	28	3	delays	delay	VERB
gs-3921	28	4	regulatory	regulatory	ADJ
gs-3921	28	5	actions	action	NOUN
gs-3921	28	6	,	,	PUNCT
gs-3921	28	7	compromises	compromise	VERB
gs-3921	28	8	patient	patient	ADJ
gs-3921	28	9	outcomes	outcome	NOUN
gs-3921	28	10	,	,	PUNCT
gs-3921	28	11	and	and	CCONJ
gs-3921	28	12	perpetuates	perpetuate	VERB
gs-3921	28	13	preventable	preventable	ADJ
gs-3921	28	14	harm	harm	NOUN
gs-3921	28	15	.	.	PUNCT
gs-3921	29	1	furthermore	furthermore	ADV
gs-3921	29	2	,	,	PUNCT
gs-3921	29	3	the	the	DET
gs-3921	29	4	growing	grow	VERB
gs-3921	29	5	complexity	complexity	NOUN
gs-3921	29	6	of	of	ADP
gs-3921	29	7	biologics	biologic	NOUN
gs-3921	29	8	,	,	PUNCT
gs-3921	29	9	biosimilars	biosimilar	NOUN
gs-3921	29	10	,	,	PUNCT
gs-3921	29	11	and	and	CCONJ
gs-3921	29	12	gene	gene	NOUN
gs-3921	29	13	therapies	therapy	NOUN
gs-3921	29	14	presents	present	VERB
gs-3921	29	15	novel	novel	ADJ
gs-3921	29	16	safety	safety	NOUN
gs-3921	29	17	concerns	concern	NOUN
gs-3921	29	18	that	that	PRON
gs-3921	29	19	exceed	exceed	VERB
gs-3921	29	20	the	the	DET
gs-3921	29	21	capabilities	capability	NOUN
gs-3921	29	22	of	of	ADP
gs-3921	29	23	traditional	traditional	ADJ
gs-3921	29	24	monitoring	monitoring	NOUN
gs-3921	29	25	systems	system	NOUN
gs-3921	29	26	and	and	CCONJ
gs-3921	29	27	demand	demand	NOUN
gs-3921	29	28	adaptive	adaptive	ADJ
gs-3921	29	29	,	,	PUNCT
gs-3921	29	30	predictive	predictive	ADJ
gs-3921	29	31	,	,	PUNCT
gs-3921	29	32	and	and	CCONJ
gs-3921	29	33	machine	machine	NOUN
gs-3921	29	34	-	-	PUNCT
gs-3921	29	35	learning	learning	NOUN
gs-3921	29	36	-	-	PUNCT
gs-3921	29	37	driven	drive	VERB
gs-3921	29	38	approaches	approach	NOUN
gs-3921	29	39	.	.	PUNCT
gs-3921	30	1	the	the	DET
gs-3921	30	2	global	global	ADJ
gs-3921	30	3	burden	burden	NOUN
gs-3921	30	4	of	of	ADP
gs-3921	30	5	drug	drug	NOUN
gs-3921	30	6	-	-	PUNCT
gs-3921	30	7	induced	induce	VERB
gs-3921	30	8	adverse	adverse	ADJ
gs-3921	30	9	effects	effect	NOUN
gs-3921	30	10	necessitates	necessitate	VERB
gs-3921	30	11	a	a	DET
gs-3921	30	12	re	re	NOUN
gs-3921	30	13	-	-	NOUN
gs-3921	30	14	evaluation	evaluation	NOUN
gs-3921	30	15	of	of	ADP
gs-3921	30	16	current	current	ADJ
gs-3921	30	17	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	30	18	paradigms	paradigm	NOUN
gs-3921	30	19	,	,	PUNCT
gs-3921	30	20	with	with	ADP
gs-3921	30	21	a	a	DET
gs-3921	30	22	focus	focus	NOUN
gs-3921	30	23	on	on	ADP
gs-3921	30	24	preemptive	preemptive	ADJ
gs-3921	30	25	risk	risk	NOUN
gs-3921	30	26	stratification	stratification	NOUN
gs-3921	30	27	and	and	CCONJ
gs-3921	30	28	individualized	individualized	ADJ
gs-3921	30	29	treatment	treatment	NOUN
gs-3921	30	30	strategies	strategy	NOUN
gs-3921	30	31	.	.	PUNCT
gs-3921	31	1	this	this	PRON
gs-3921	31	2	includes	include	VERB
gs-3921	31	3	the	the	DET
gs-3921	31	4	incorporation	incorporation	NOUN
gs-3921	31	5	of	of	ADP
gs-3921	31	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	31	7	testing	testing	NOUN
gs-3921	31	8	in	in	ADP
gs-3921	31	9	routine	routine	ADJ
gs-3921	31	10	care	care	NOUN
gs-3921	31	11	pathways	pathway	NOUN
gs-3921	31	12	,	,	PUNCT
gs-3921	31	13	especially	especially	ADV
gs-3921	31	14	for	for	ADP
gs-3921	31	15	high	high	ADJ
gs-3921	31	16	-	-	PUNCT
gs-3921	31	17	risk	risk	NOUN
gs-3921	31	18	drugs	drug	NOUN
gs-3921	31	19	with	with	ADP
gs-3921	31	20	narrow	narrow	ADJ
gs-3921	31	21	therapeutic	therapeutic	ADJ
gs-3921	31	22	indices	index	NOUN
gs-3921	31	23	or	or	CCONJ
gs-3921	31	24	known	know	VERB
gs-3921	31	25	immunogenic	immunogenic	ADJ
gs-3921	31	26	potential	potential	NOUN
gs-3921	31	27	.	.	PUNCT
gs-3921	32	1	strategic	strategic	ADJ
gs-3921	32	2	integration	integration	NOUN
gs-3921	32	3	of	of	ADP
gs-3921	32	4	genomic	genomic	ADJ
gs-3921	32	5	data	datum	NOUN
gs-3921	32	6	with	with	ADP
gs-3921	32	7	clinical	clinical	ADJ
gs-3921	32	8	phenotypes	phenotype	NOUN
gs-3921	32	9	and	and	CCONJ
gs-3921	32	10	real	real	ADJ
gs-3921	32	11	-	-	PUNCT
gs-3921	32	12	world	world	NOUN
gs-3921	32	13	evidence	evidence	NOUN
gs-3921	32	14	offers	offer	VERB
gs-3921	32	15	unprecedented	unprecedented	ADJ
gs-3921	32	16	opportunities	opportunity	NOUN
gs-3921	32	17	for	for	ADP
gs-3921	32	18	precision	precision	NOUN
gs-3921	32	19	prescribing	prescribing	NOUN
gs-3921	32	20	and	and	CCONJ
gs-3921	32	21	early	early	ADJ
gs-3921	32	22	toxicity	toxicity	NOUN
gs-3921	32	23	mitigation	mitigation	NOUN
gs-3921	32	24	.	.	PUNCT
gs-3921	33	1	however	however	ADV
gs-3921	33	2	,	,	PUNCT
gs-3921	33	3	this	this	PRON
gs-3921	33	4	requires	require	VERB
gs-3921	33	5	interdisciplinary	interdisciplinary	ADJ
gs-3921	33	6	collaboration	collaboration	NOUN
gs-3921	33	7	among	among	ADP
gs-3921	33	8	geneticists	geneticist	NOUN
gs-3921	33	9	,	,	PUNCT
gs-3921	33	10	clinical	clinical	ADJ
gs-3921	33	11	pharmacologists	pharmacologist	NOUN
gs-3921	33	12	,	,	PUNCT
gs-3921	33	13	toxicologists	toxicologist	NOUN
gs-3921	33	14	,	,	PUNCT
gs-3921	33	15	data	datum	NOUN
gs-3921	33	16	scientists	scientist	NOUN
gs-3921	33	17	,	,	PUNCT
gs-3921	33	18	and	and	CCONJ
gs-3921	33	19	healthcare	healthcare	PROPN
gs-3921	33	20	professionals	professional	NOUN
gs-3921	33	21	,	,	PUNCT
gs-3921	33	22	underpinned	underpin	VERB
gs-3921	33	23	by	by	ADP
gs-3921	33	24	supportive	supportive	ADJ
gs-3921	33	25	policy	policy	NOUN
gs-3921	33	26	frameworks	framework	NOUN
gs-3921	33	27	and	and	CCONJ
gs-3921	33	28	patient	patient	NOUN
gs-3921	33	29	-	-	PUNCT
gs-3921	33	30	centered	center	VERB
gs-3921	33	31	education	education	NOUN
gs-3921	33	32	initiatives	initiative	NOUN
gs-3921	33	33	.	.	PUNCT
gs-3921	34	1	this	this	DET
gs-3921	34	2	review	review	NOUN
gs-3921	34	3	also	also	ADV
gs-3921	34	4	synthesizes	synthesize	VERB
gs-3921	34	5	existing	exist	VERB
gs-3921	34	6	knowledge	knowledge	NOUN
gs-3921	34	7	on	on	ADP
gs-3921	34	8	drug	drug	NOUN
gs-3921	34	9	classes	class	NOUN
gs-3921	34	10	most	most	ADV
gs-3921	34	11	frequently	frequently	ADV
gs-3921	34	12	implicated	implicate	VERB
gs-3921	34	13	in	in	ADP
gs-3921	34	14	severe	severe	ADJ
gs-3921	34	15	adrs	adr	NOUN
gs-3921	34	16	and	and	CCONJ
gs-3921	34	17	toxicities	toxicity	NOUN
gs-3921	34	18	,	,	PUNCT
gs-3921	34	19	including	include	VERB
gs-3921	34	20	antiepileptics	antiepileptic	NOUN
gs-3921	34	21	,	,	PUNCT
gs-3921	34	22	antimicrobials	antimicrobial	NOUN
gs-3921	34	23	,	,	PUNCT
gs-3921	34	24	antineoplastics	antineoplastic	NOUN
gs-3921	34	25	,	,	PUNCT
gs-3921	34	26	immunomodulators	immunomodulator	NOUN
gs-3921	34	27	,	,	PUNCT
gs-3921	34	28	and	and	CCONJ
gs-3921	34	29	antipsychotics	antipsychotic	NOUN
gs-3921	34	30	.	.	PUNCT
gs-3921	35	1	each	each	PRON
gs-3921	35	2	of	of	ADP
gs-3921	35	3	these	these	DET
gs-3921	35	4	pharmacologic	pharmacologic	ADJ
gs-3921	35	5	groups	group	NOUN
gs-3921	35	6	demonstrates	demonstrate	VERB
gs-3921	35	7	unique	unique	ADJ
gs-3921	35	8	toxicity	toxicity	NOUN
gs-3921	35	9	profiles	profile	NOUN
gs-3921	35	10	influenced	influence	VERB
gs-3921	35	11	by	by	ADP
gs-3921	35	12	both	both	CCONJ
gs-3921	35	13	genetic	genetic	ADJ
gs-3921	35	14	and	and	CCONJ
gs-3921	35	15	nongenetic	nongenetic	ADJ
gs-3921	35	16	mechanisms	mechanism	NOUN
gs-3921	35	17	.	.	PUNCT
gs-3921	36	1	for	for	ADP
gs-3921	36	2	instance	instance	NOUN
gs-3921	36	3	,	,	PUNCT
gs-3921	36	4	flucloxacillin	flucloxacillin	NOUN
gs-3921	36	5	-	-	PUNCT
gs-3921	36	6	induced	induce	VERB
gs-3921	36	7	liver	liver	NOUN
gs-3921	36	8	injury	injury	NOUN
gs-3921	36	9	,	,	PUNCT
gs-3921	36	10	methotrexate	methotrexate	NOUN
gs-3921	36	11	-	-	PUNCT
gs-3921	36	12	associated	associate	VERB
gs-3921	36	13	mucosal	mucosal	NOUN
gs-3921	36	14	and	and	CCONJ
gs-3921	36	15	hematologic	hematologic	NOUN
gs-3921	36	16	toxicity	toxicity	NOUN
gs-3921	36	17	,	,	PUNCT
gs-3921	36	18	and	and	CCONJ
gs-3921	36	19	clozapine	clozapine	NOUN
gs-3921	36	20	-	-	PUNCT
gs-3921	36	21	induced	induce	VERB
gs-3921	36	22	agranulocytosis	agranulocytosis	NOUN
gs-3921	36	23	illustrate	illustrate	VERB
gs-3921	36	24	how	how	SCONJ
gs-3921	36	25	drug	drug	NOUN
gs-3921	36	26	-	-	PUNCT
gs-3921	36	27	specific	specific	ADJ
gs-3921	36	28	adverse	adverse	ADJ
gs-3921	36	29	events	event	NOUN
gs-3921	36	30	can	can	AUX
gs-3921	36	31	lead	lead	VERB
gs-3921	36	32	to	to	ADP
gs-3921	36	33	substantial	substantial	ADJ
gs-3921	36	34	morbidity	morbidity	NOUN
gs-3921	36	35	and	and	CCONJ
gs-3921	36	36	mortality	mortality	NOUN
gs-3921	36	37	.	.	PUNCT
gs-3921	37	1	finally	finally	ADV
gs-3921	37	2	,	,	PUNCT
gs-3921	37	3	the	the	DET
gs-3921	37	4	strategic	strategic	ADJ
gs-3921	37	5	management	management	NOUN
gs-3921	37	6	of	of	ADP
gs-3921	37	7	medication	medication	NOUN
gs-3921	37	8	-	-	PUNCT
gs-3921	37	9	induced	induce	VERB
gs-3921	37	10	toxicities	toxicity	NOUN
gs-3921	37	11	calls	call	VERB
gs-3921	37	12	for	for	SCONJ
gs-3921	37	13	georgian	georgian	ADJ
gs-3921	37	14	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	37	15	მეცნიერები	მეცნიერები	NOUN
gs-3921	37	16	ტ.	ტ.	VERB
gs-3921	37	17	7	7	NUM
gs-3921	37	18	n	n	DET
gs-3921	37	19	3	3	NUM
gs-3921	37	20	,	,	PUNCT
gs-3921	37	21	2025	2025	NUM
gs-3921	37	22	220	220	NUM
gs-3921	37	23	a	a	DET
gs-3921	37	24	multifaceted	multifaceted	ADJ
gs-3921	37	25	approach	approach	NOUN
gs-3921	37	26	encompassing	encompass	VERB
gs-3921	37	27	early	early	ADJ
gs-3921	37	28	recognition	recognition	NOUN
gs-3921	37	29	,	,	PUNCT
gs-3921	37	30	immediate	immediate	ADJ
gs-3921	37	31	intervention	intervention	NOUN
gs-3921	37	32	,	,	PUNCT
gs-3921	37	33	longitudinal	longitudinal	ADJ
gs-3921	37	34	follow	follow	NOUN
gs-3921	37	35	-	-	PUNCT
gs-3921	37	36	up	up	NOUN
gs-3921	37	37	,	,	PUNCT
gs-3921	37	38	and	and	CCONJ
gs-3921	37	39	patient	patient	ADJ
gs-3921	37	40	empowerment	empowerment	NOUN
gs-3921	37	41	.	.	PUNCT
gs-3921	38	1	therapeutic	therapeutic	ADJ
gs-3921	38	2	strategies	strategy	NOUN
gs-3921	38	3	may	may	AUX
gs-3921	38	4	involve	involve	VERB
gs-3921	38	5	drug	drug	NOUN
gs-3921	38	6	withdrawal	withdrawal	NOUN
gs-3921	38	7	,	,	PUNCT
gs-3921	38	8	substitution	substitution	NOUN
gs-3921	38	9	with	with	ADP
gs-3921	38	10	safer	safe	ADJ
gs-3921	38	11	alternatives	alternative	NOUN
gs-3921	38	12	,	,	PUNCT
gs-3921	38	13	immunosuppressive	immunosuppressive	ADJ
gs-3921	38	14	therapy	therapy	NOUN
gs-3921	38	15	in	in	ADP
gs-3921	38	16	hypersensitivity	hypersensitivity	NOUN
gs-3921	38	17	syndromes	syndrome	NOUN
gs-3921	38	18	,	,	PUNCT
gs-3921	38	19	supportive	supportive	ADJ
gs-3921	38	20	care	care	NOUN
gs-3921	38	21	,	,	PUNCT
gs-3921	38	22	and	and	CCONJ
gs-3921	38	23	desensitization	desensitization	NOUN
gs-3921	38	24	protocols	protocol	NOUN
gs-3921	38	25	where	where	SCONJ
gs-3921	38	26	appropriate	appropriate	ADJ
gs-3921	38	27	.	.	PUNCT
gs-3921	39	1	clinical	clinical	ADJ
gs-3921	39	2	decision	decision	NOUN
gs-3921	39	3	-	-	PUNCT
gs-3921	39	4	making	making	NOUN
gs-3921	39	5	must	must	AUX
gs-3921	39	6	be	be	AUX
gs-3921	39	7	informed	inform	VERB
gs-3921	39	8	by	by	ADP
gs-3921	39	9	timely	timely	ADJ
gs-3921	39	10	diagnostic	diagnostic	ADJ
gs-3921	39	11	evaluations	evaluation	NOUN
gs-3921	39	12	,	,	PUNCT
gs-3921	39	13	including	include	VERB
gs-3921	39	14	blood	blood	NOUN
gs-3921	39	15	counts	count	NOUN
gs-3921	39	16	,	,	PUNCT
gs-3921	39	17	liver	liver	NOUN
gs-3921	39	18	and	and	CCONJ
gs-3921	39	19	renal	renal	ADJ
gs-3921	39	20	function	function	NOUN
gs-3921	39	21	tests	test	NOUN
gs-3921	39	22	,	,	PUNCT
gs-3921	39	23	skin	skin	NOUN
gs-3921	39	24	biopsies	biopsy	NOUN
gs-3921	39	25	,	,	PUNCT
gs-3921	39	26	and	and	CCONJ
gs-3921	39	27	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	39	28	assays	assay	NOUN
gs-3921	39	29	.	.	PUNCT
gs-3921	40	1	equally	equally	ADV
gs-3921	40	2	critical	critical	ADJ
gs-3921	40	3	is	be	AUX
gs-3921	40	4	the	the	DET
gs-3921	40	5	need	need	NOUN
gs-3921	40	6	to	to	PART
gs-3921	40	7	strengthen	strengthen	VERB
gs-3921	40	8	healthcare	healthcare	PROPN
gs-3921	40	9	systems	system	NOUN
gs-3921	40	10	’	'	PUNCT
gs-3921	40	11	capacity	capacity	NOUN
gs-3921	40	12	to	to	PART
gs-3921	40	13	deliver	deliver	VERB
gs-3921	40	14	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	40	15	education	education	NOUN
gs-3921	40	16	,	,	PUNCT
gs-3921	40	17	establish	establish	VERB
gs-3921	40	18	multidisciplinary	multidisciplinary	ADJ
gs-3921	40	19	adr	adr	PROPN
gs-3921	40	20	committees	committee	NOUN
gs-3921	40	21	,	,	PUNCT
gs-3921	40	22	and	and	CCONJ
gs-3921	40	23	develop	develop	VERB
gs-3921	40	24	national	national	ADJ
gs-3921	40	25	and	and	CCONJ
gs-3921	40	26	international	international	ADJ
gs-3921	40	27	safety	safety	NOUN
gs-3921	40	28	databases	database	NOUN
gs-3921	40	29	that	that	PRON
gs-3921	40	30	promote	promote	VERB
gs-3921	40	31	transparent	transparent	ADJ
gs-3921	40	32	information	information	NOUN
gs-3921	40	33	exchange	exchange	NOUN
gs-3921	40	34	.	.	PUNCT
gs-3921	41	1	this	this	DET
gs-3921	41	2	comprehensive	comprehensive	ADJ
gs-3921	41	3	investigation	investigation	NOUN
gs-3921	41	4	underscores	underscore	VERB
gs-3921	41	5	the	the	DET
gs-3921	41	6	critical	critical	ADJ
gs-3921	41	7	importance	importance	NOUN
gs-3921	41	8	of	of	ADP
gs-3921	41	9	integrating	integrate	VERB
gs-3921	41	10	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	41	11	insights	insight	NOUN
gs-3921	41	12	with	with	ADP
gs-3921	41	13	clinical	clinical	ADJ
gs-3921	41	14	risk	risk	NOUN
gs-3921	41	15	assessment	assessment	NOUN
gs-3921	41	16	to	to	PART
gs-3921	41	17	effectively	effectively	ADV
gs-3921	41	18	manage	manage	VERB
gs-3921	41	19	medicationinduced	medicationinduced	ADJ
gs-3921	41	20	adverse	adverse	ADJ
gs-3921	41	21	effects	effect	NOUN
gs-3921	41	22	and	and	CCONJ
gs-3921	41	23	toxicities	toxicity	NOUN
gs-3921	41	24	.	.	PUNCT
gs-3921	42	1	as	as	SCONJ
gs-3921	42	2	healthcare	healthcare	PROPN
gs-3921	42	3	systems	system	NOUN
gs-3921	42	4	move	move	VERB
gs-3921	42	5	toward	toward	ADP
gs-3921	42	6	precision	precision	NOUN
gs-3921	42	7	medicine	medicine	NOUN
gs-3921	42	8	and	and	CCONJ
gs-3921	42	9	individualized	individualized	ADJ
gs-3921	42	10	care	care	NOUN
gs-3921	42	11	,	,	PUNCT
gs-3921	42	12	the	the	DET
gs-3921	42	13	harmonization	harmonization	NOUN
gs-3921	42	14	of	of	ADP
gs-3921	42	15	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	42	16	practices	practice	NOUN
gs-3921	42	17	,	,	PUNCT
gs-3921	42	18	regulatory	regulatory	ADJ
gs-3921	42	19	reforms	reform	NOUN
gs-3921	42	20	,	,	PUNCT
gs-3921	42	21	and	and	CCONJ
gs-3921	42	22	patient	patient	ADJ
gs-3921	42	23	-	-	PUNCT
gs-3921	42	24	centric	centric	ADJ
gs-3921	42	25	education	education	NOUN
gs-3921	42	26	becomes	become	VERB
gs-3921	42	27	paramount	paramount	ADJ
gs-3921	42	28	.	.	PUNCT
gs-3921	43	1	only	only	ADV
gs-3921	43	2	through	through	ADP
gs-3921	43	3	a	a	DET
gs-3921	43	4	concerted	concerted	ADJ
gs-3921	43	5	global	global	ADJ
gs-3921	43	6	effort	effort	NOUN
gs-3921	43	7	—	—	PUNCT
gs-3921	43	8	uniting	unite	VERB
gs-3921	43	9	scientific	scientific	ADJ
gs-3921	43	10	,	,	PUNCT
gs-3921	43	11	clinical	clinical	ADJ
gs-3921	43	12	,	,	PUNCT
gs-3921	43	13	and	and	CCONJ
gs-3921	43	14	technological	technological	ADJ
gs-3921	43	15	advances	advance	NOUN
gs-3921	43	16	—	—	PUNCT
gs-3921	43	17	can	can	AUX
gs-3921	43	18	we	we	PRON
gs-3921	43	19	hope	hope	VERB
gs-3921	43	20	to	to	PART
gs-3921	43	21	reduce	reduce	VERB
gs-3921	43	22	the	the	DET
gs-3921	43	23	incidence	incidence	NOUN
gs-3921	43	24	and	and	CCONJ
gs-3921	43	25	burden	burden	NOUN
gs-3921	43	26	of	of	ADP
gs-3921	43	27	drug	drug	NOUN
gs-3921	43	28	-	-	PUNCT
gs-3921	43	29	related	relate	VERB
gs-3921	43	30	toxicities	toxicity	NOUN
gs-3921	43	31	,	,	PUNCT
gs-3921	43	32	optimize	optimize	VERB
gs-3921	43	33	therapeutic	therapeutic	ADJ
gs-3921	43	34	outcomes	outcome	NOUN
gs-3921	43	35	,	,	PUNCT
gs-3921	43	36	and	and	CCONJ
gs-3921	43	37	safeguard	safeguard	VERB
gs-3921	43	38	public	public	ADJ
gs-3921	43	39	health	health	NOUN
gs-3921	43	40	in	in	ADP
gs-3921	43	41	the	the	DET
gs-3921	43	42	era	era	NOUN
gs-3921	43	43	of	of	ADP
gs-3921	43	44	increasingly	increasingly	ADV
gs-3921	43	45	complex	complex	ADJ
gs-3921	43	46	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	43	47	.	.	PUNCT
gs-3921	44	1	keywords	keyword	NOUN
gs-3921	44	2	:	:	PUNCT
gs-3921	44	3	drug	drug	NOUN
gs-3921	44	4	characteristics	characteristic	NOUN
gs-3921	44	5	,	,	PUNCT
gs-3921	44	6	side	side	NOUN
gs-3921	44	7	effects	effect	NOUN
gs-3921	44	8	,	,	PUNCT
gs-3921	44	9	induced	induce	VERB
gs-3921	44	10	drug	drug	NOUN
gs-3921	44	11	reaction	reaction	NOUN
gs-3921	44	12	,	,	PUNCT
gs-3921	44	13	eosinophilia	eosinophilia	PROPN
gs-3921	44	14	and	and	CCONJ
gs-3921	44	15	systemic	systemic	ADJ
gs-3921	44	16	symptoms	symptom	NOUN
gs-3921	44	17	.	.	PUNCT
gs-3921	45	1	introduction	introduction	NOUN
gs-3921	45	2	the	the	DET
gs-3921	45	3	contemporary	contemporary	ADJ
gs-3921	45	4	landscape	landscape	NOUN
gs-3921	45	5	of	of	ADP
gs-3921	45	6	medical	medical	ADJ
gs-3921	45	7	science	science	NOUN
gs-3921	45	8	is	be	AUX
gs-3921	45	9	rapidly	rapidly	ADV
gs-3921	45	10	evolving	evolve	VERB
gs-3921	45	11	toward	toward	ADP
gs-3921	45	12	precision	precision	NOUN
gs-3921	45	13	medicine	medicine	NOUN
gs-3921	45	14	,	,	PUNCT
gs-3921	45	15	where	where	SCONJ
gs-3921	45	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	45	17	insights	insight	NOUN
gs-3921	45	18	and	and	CCONJ
gs-3921	45	19	individualized	individualized	ADJ
gs-3921	45	20	care	care	NOUN
gs-3921	45	21	paradigms	paradigm	NOUN
gs-3921	45	22	are	be	AUX
gs-3921	45	23	gaining	gain	VERB
gs-3921	45	24	unprecedented	unprecedented	ADJ
gs-3921	45	25	prominence	prominence	NOUN
gs-3921	45	26	.	.	PUNCT
gs-3921	46	1	this	this	DET
gs-3921	46	2	evolution	evolution	NOUN
gs-3921	46	3	is	be	AUX
gs-3921	46	4	driven	drive	VERB
gs-3921	46	5	by	by	ADP
gs-3921	46	6	the	the	DET
gs-3921	46	7	recognition	recognition	NOUN
gs-3921	46	8	that	that	SCONJ
gs-3921	46	9	adverse	adverse	ADJ
gs-3921	46	10	drug	drug	NOUN
gs-3921	46	11	reactions	reaction	NOUN
gs-3921	46	12	and	and	CCONJ
gs-3921	46	13	medication	medication	NOUN
gs-3921	46	14	-	-	PUNCT
gs-3921	46	15	induced	induce	VERB
gs-3921	46	16	toxicities	toxicity	NOUN
gs-3921	46	17	remain	remain	VERB
gs-3921	46	18	among	among	ADP
gs-3921	46	19	the	the	DET
gs-3921	46	20	leading	lead	VERB
gs-3921	46	21	causes	cause	NOUN
gs-3921	46	22	of	of	ADP
gs-3921	46	23	morbidity	morbidity	NOUN
gs-3921	46	24	and	and	CCONJ
gs-3921	46	25	mortality	mortality	NOUN
gs-3921	46	26	worldwide	worldwide	ADV
gs-3921	46	27	,	,	PUNCT
gs-3921	46	28	despite	despite	SCONJ
gs-3921	46	29	extensive	extensive	ADJ
gs-3921	46	30	advancements	advancement	NOUN
gs-3921	46	31	in	in	ADP
gs-3921	46	32	drug	drug	NOUN
gs-3921	46	33	development	development	NOUN
gs-3921	46	34	,	,	PUNCT
gs-3921	46	35	clinical	clinical	ADJ
gs-3921	46	36	pharmacology	pharmacology	NOUN
gs-3921	46	37	,	,	PUNCT
gs-3921	46	38	and	and	CCONJ
gs-3921	46	39	regulatory	regulatory	ADJ
gs-3921	46	40	oversight	oversight	NOUN
gs-3921	46	41	.	.	PUNCT
gs-3921	47	1	these	these	DET
gs-3921	47	2	adverse	adverse	ADJ
gs-3921	47	3	outcomes	outcome	NOUN
gs-3921	47	4	are	be	AUX
gs-3921	47	5	often	often	ADV
gs-3921	47	6	unpredictable	unpredictable	ADJ
gs-3921	47	7	,	,	PUNCT
gs-3921	47	8	multifactorial	multifactorial	ADJ
gs-3921	47	9	in	in	ADP
gs-3921	47	10	origin	origin	NOUN
gs-3921	47	11	,	,	PUNCT
gs-3921	47	12	and	and	CCONJ
gs-3921	47	13	rooted	root	VERB
gs-3921	47	14	in	in	ADP
gs-3921	47	15	the	the	DET
gs-3921	47	16	complex	complex	ADJ
gs-3921	47	17	interplay	interplay	NOUN
gs-3921	47	18	between	between	ADP
gs-3921	47	19	a	a	DET
gs-3921	47	20	patient	patient	NOUN
gs-3921	47	21	's	's	PART
gs-3921	47	22	unique	unique	ADJ
gs-3921	47	23	genetic	genetic	ADJ
gs-3921	47	24	makeup	makeup	NOUN
gs-3921	47	25	,	,	PUNCT
gs-3921	47	26	environmental	environmental	ADJ
gs-3921	47	27	exposures	exposure	NOUN
gs-3921	47	28	,	,	PUNCT
gs-3921	47	29	comorbid	comorbid	NOUN
gs-3921	47	30	conditions	condition	NOUN
gs-3921	47	31	,	,	PUNCT
gs-3921	47	32	and	and	CCONJ
gs-3921	47	33	pharmacological	pharmacological	ADJ
gs-3921	47	34	characteristics	characteristic	NOUN
gs-3921	47	35	of	of	ADP
gs-3921	47	36	therapeutic	therapeutic	ADJ
gs-3921	47	37	agents	agent	NOUN
gs-3921	47	38	.	.	PUNCT
gs-3921	48	1	the	the	DET
gs-3921	48	2	increasing	increase	VERB
gs-3921	48	3	prevalence	prevalence	NOUN
gs-3921	48	4	of	of	ADP
gs-3921	48	5	such	such	ADJ
gs-3921	48	6	events	event	NOUN
gs-3921	48	7	has	have	AUX
gs-3921	48	8	intensified	intensify	VERB
gs-3921	48	9	the	the	DET
gs-3921	48	10	demand	demand	NOUN
gs-3921	48	11	for	for	ADP
gs-3921	48	12	a	a	DET
gs-3921	48	13	deeper	deep	ADJ
gs-3921	48	14	scientific	scientific	ADJ
gs-3921	48	15	inquiry	inquiry	NOUN
gs-3921	48	16	into	into	ADP
gs-3921	48	17	the	the	DET
gs-3921	48	18	mechanisms	mechanism	NOUN
gs-3921	48	19	,	,	PUNCT
gs-3921	48	20	determinants	determinant	NOUN
gs-3921	48	21	,	,	PUNCT
gs-3921	48	22	and	and	CCONJ
gs-3921	48	23	mitigation	mitigation	NOUN
gs-3921	48	24	strategies	strategy	NOUN
gs-3921	48	25	associated	associate	VERB
gs-3921	48	26	with	with	ADP
gs-3921	48	27	drug	drug	NOUN
gs-3921	48	28	-	-	PUNCT
gs-3921	48	29	induced	induce	VERB
gs-3921	48	30	adverse	adverse	ADJ
gs-3921	48	31	effects	effect	NOUN
gs-3921	48	32	.	.	PUNCT
gs-3921	49	1	a	a	DET
gs-3921	49	2	fundamental	fundamental	ADJ
gs-3921	49	3	aspect	aspect	NOUN
gs-3921	49	4	of	of	ADP
gs-3921	49	5	this	this	DET
gs-3921	49	6	inquiry	inquiry	NOUN
gs-3921	49	7	lies	lie	VERB
gs-3921	49	8	in	in	ADP
gs-3921	49	9	the	the	DET
gs-3921	49	10	realm	realm	NOUN
gs-3921	49	11	of	of	ADP
gs-3921	49	12	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	49	13	,	,	PUNCT
gs-3921	49	14	a	a	DET
gs-3921	49	15	discipline	discipline	NOUN
gs-3921	49	16	that	that	PRON
gs-3921	49	17	explores	explore	VERB
gs-3921	49	18	the	the	DET
gs-3921	49	19	genetic	genetic	ADJ
gs-3921	49	20	determinants	determinant	NOUN
gs-3921	49	21	influencing	influence	VERB
gs-3921	49	22	an	an	DET
gs-3921	49	23	individual	individual	NOUN
gs-3921	49	24	’s	’s	PART
gs-3921	49	25	response	response	NOUN
gs-3921	49	26	to	to	ADP
gs-3921	49	27	medications	medication	NOUN
gs-3921	49	28	.	.	PUNCT
gs-3921	50	1	by	by	ADP
gs-3921	50	2	elucidating	elucidate	VERB
gs-3921	50	3	how	how	SCONJ
gs-3921	50	4	genetic	genetic	ADJ
gs-3921	50	5	polymorphisms	polymorphism	NOUN
gs-3921	50	6	affect	affect	VERB
gs-3921	50	7	drug	drug	NOUN
gs-3921	50	8	metabolism	metabolism	NOUN
gs-3921	50	9	,	,	PUNCT
gs-3921	50	10	efficacy	efficacy	NOUN
gs-3921	50	11	,	,	PUNCT
gs-3921	50	12	and	and	CCONJ
gs-3921	50	13	toxicity	toxicity	NOUN
gs-3921	50	14	,	,	PUNCT
gs-3921	50	15	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	50	16	offers	offer	VERB
gs-3921	50	17	a	a	DET
gs-3921	50	18	compelling	compelling	ADJ
gs-3921	50	19	framework	framework	NOUN
gs-3921	50	20	to	to	PART
gs-3921	50	21	tailor	tailor	VERB
gs-3921	50	22	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	50	23	regimens	regimen	NOUN
gs-3921	50	24	in	in	ADP
gs-3921	50	25	a	a	DET
gs-3921	50	26	manner	manner	NOUN
gs-3921	50	27	that	that	PRON
gs-3921	50	28	minimizes	minimize	VERB
gs-3921	50	29	risk	risk	NOUN
gs-3921	50	30	while	while	SCONJ
gs-3921	50	31	optimizing	optimize	VERB
gs-3921	50	32	therapeutic	therapeutic	ADJ
gs-3921	50	33	outcomes	outcome	NOUN
gs-3921	50	34	.	.	PUNCT
gs-3921	51	1	these	these	DET
gs-3921	51	2	insights	insight	NOUN
gs-3921	51	3	hold	hold	VERB
gs-3921	51	4	the	the	DET
gs-3921	51	5	promise	promise	NOUN
gs-3921	51	6	of	of	ADP
gs-3921	51	7	transforming	transform	VERB
gs-3921	51	8	traditional	traditional	ADJ
gs-3921	51	9	reactive	reactive	ADJ
gs-3921	51	10	healthcare	healthcare	NOUN
gs-3921	51	11	approaches	approach	NOUN
gs-3921	51	12	into	into	ADP
gs-3921	51	13	proactive	proactive	ADJ
gs-3921	51	14	and	and	CCONJ
gs-3921	51	15	preventive	preventive	ADJ
gs-3921	51	16	strategies	strategy	NOUN
gs-3921	51	17	,	,	PUNCT
gs-3921	51	18	where	where	SCONJ
gs-3921	51	19	the	the	DET
gs-3921	51	20	right	right	ADJ
gs-3921	51	21	drug	drug	NOUN
gs-3921	51	22	is	be	AUX
gs-3921	51	23	administered	administer	VERB
gs-3921	51	24	to	to	ADP
gs-3921	51	25	the	the	DET
gs-3921	51	26	right	right	ADJ
gs-3921	51	27	patient	patient	NOUN
gs-3921	51	28	at	at	ADP
gs-3921	51	29	the	the	DET
gs-3921	51	30	right	right	ADJ
gs-3921	51	31	dose	dose	NOUN
gs-3921	51	32	and	and	CCONJ
gs-3921	51	33	time	time	NOUN
gs-3921	51	34	.	.	PUNCT
gs-3921	52	1	despite	despite	SCONJ
gs-3921	52	2	the	the	DET
gs-3921	52	3	potential	potential	NOUN
gs-3921	52	4	,	,	PUNCT
gs-3921	52	5	the	the	DET
gs-3921	52	6	georgian	georgian	ADJ
gs-3921	52	7	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	52	8	მეცნიერები	მეცნიერები	NOUN
gs-3921	52	9	ტ.	ტ.	VERB
gs-3921	52	10	7	7	NUM
gs-3921	52	11	n	n	DET
gs-3921	52	12	3	3	NUM
gs-3921	52	13	,	,	PUNCT
gs-3921	52	14	2025	2025	NUM
gs-3921	52	15	221	221	NUM
gs-3921	52	16	integration	integration	NOUN
gs-3921	52	17	of	of	ADP
gs-3921	52	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	52	19	data	datum	NOUN
gs-3921	52	20	into	into	ADP
gs-3921	52	21	clinical	clinical	ADJ
gs-3921	52	22	practice	practice	NOUN
gs-3921	52	23	remains	remain	VERB
gs-3921	52	24	sporadic	sporadic	ADJ
gs-3921	52	25	and	and	CCONJ
gs-3921	52	26	challenged	challenge	VERB
gs-3921	52	27	by	by	ADP
gs-3921	52	28	regulatory	regulatory	ADJ
gs-3921	52	29	gaps	gap	NOUN
gs-3921	52	30	,	,	PUNCT
gs-3921	52	31	limited	limited	ADJ
gs-3921	52	32	clinician	clinician	NOUN
gs-3921	52	33	awareness	awareness	NOUN
gs-3921	52	34	,	,	PUNCT
gs-3921	52	35	and	and	CCONJ
gs-3921	52	36	infrastructural	infrastructural	ADJ
gs-3921	52	37	deficiencies	deficiency	NOUN
gs-3921	52	38	,	,	PUNCT
gs-3921	52	39	particularly	particularly	ADV
gs-3921	52	40	in	in	ADP
gs-3921	52	41	developing	develop	VERB
gs-3921	52	42	health	health	NOUN
gs-3921	52	43	systems	system	NOUN
gs-3921	52	44	.	.	PUNCT
gs-3921	53	1	simultaneously	simultaneously	ADV
gs-3921	53	2	,	,	PUNCT
gs-3921	53	3	the	the	DET
gs-3921	53	4	emergence	emergence	NOUN
gs-3921	53	5	of	of	ADP
gs-3921	53	6	patient	patient	NOUN
gs-3921	53	7	-	-	PUNCT
gs-3921	53	8	centered	center	VERB
gs-3921	53	9	care	care	NOUN
gs-3921	53	10	as	as	ADP
gs-3921	53	11	a	a	DET
gs-3921	53	12	cornerstone	cornerstone	NOUN
gs-3921	53	13	of	of	ADP
gs-3921	53	14	modern	modern	ADJ
gs-3921	53	15	healthcare	healthcare	NOUN
gs-3921	53	16	underscores	underscore	VERB
gs-3921	53	17	the	the	DET
gs-3921	53	18	necessity	necessity	NOUN
gs-3921	53	19	of	of	ADP
gs-3921	53	20	viewing	view	VERB
gs-3921	53	21	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	53	22	through	through	ADP
gs-3921	53	23	a	a	DET
gs-3921	53	24	holistic	holistic	ADJ
gs-3921	53	25	lens	lens	NOUN
gs-3921	53	26	that	that	PRON
gs-3921	53	27	transcends	transcend	VERB
gs-3921	53	28	biochemical	biochemical	ADJ
gs-3921	53	29	and	and	CCONJ
gs-3921	53	30	genetic	genetic	ADJ
gs-3921	53	31	parameters	parameter	NOUN
gs-3921	53	32	.	.	PUNCT
gs-3921	54	1	patient	patient	NOUN
gs-3921	54	2	-	-	PUNCT
gs-3921	54	3	centered	center	VERB
gs-3921	54	4	care	care	NOUN
gs-3921	54	5	emphasizes	emphasize	VERB
gs-3921	54	6	the	the	DET
gs-3921	54	7	inclusion	inclusion	NOUN
gs-3921	54	8	of	of	ADP
gs-3921	54	9	individual	individual	ADJ
gs-3921	54	10	preferences	preference	NOUN
gs-3921	54	11	,	,	PUNCT
gs-3921	54	12	values	value	NOUN
gs-3921	54	13	,	,	PUNCT
gs-3921	54	14	and	and	CCONJ
gs-3921	54	15	lived	live	VERB
gs-3921	54	16	experiences	experience	NOUN
gs-3921	54	17	in	in	ADP
gs-3921	54	18	the	the	DET
gs-3921	54	19	therapeutic	therapeutic	ADJ
gs-3921	54	20	decision	decision	NOUN
gs-3921	54	21	-	-	PUNCT
gs-3921	54	22	making	make	VERB
gs-3921	54	23	process	process	NOUN
gs-3921	54	24	.	.	PUNCT
gs-3921	55	1	this	this	DET
gs-3921	55	2	paradigm	paradigm	NOUN
gs-3921	55	3	advocates	advocate	VERB
gs-3921	55	4	for	for	ADP
gs-3921	55	5	shared	shared	ADJ
gs-3921	55	6	decision	decision	NOUN
gs-3921	55	7	-	-	PUNCT
gs-3921	55	8	making	making	NOUN
gs-3921	55	9	,	,	PUNCT
gs-3921	55	10	informed	informed	ADJ
gs-3921	55	11	consent	consent	NOUN
gs-3921	55	12	,	,	PUNCT
gs-3921	55	13	and	and	CCONJ
gs-3921	55	14	continuous	continuous	ADJ
gs-3921	55	15	communication	communication	NOUN
gs-3921	55	16	between	between	ADP
gs-3921	55	17	patients	patient	NOUN
gs-3921	55	18	and	and	CCONJ
gs-3921	55	19	healthcare	healthcare	NOUN
gs-3921	55	20	providers	provider	NOUN
gs-3921	55	21	,	,	PUNCT
gs-3921	55	22	thereby	thereby	ADV
gs-3921	55	23	promoting	promote	VERB
gs-3921	55	24	trust	trust	NOUN
gs-3921	55	25	,	,	PUNCT
gs-3921	55	26	adherence	adherence	NOUN
gs-3921	55	27	,	,	PUNCT
gs-3921	55	28	and	and	CCONJ
gs-3921	55	29	improved	improve	VERB
gs-3921	55	30	health	health	NOUN
gs-3921	55	31	outcomes	outcome	NOUN
gs-3921	55	32	.	.	PUNCT
gs-3921	56	1	when	when	SCONJ
gs-3921	56	2	integrated	integrate	VERB
gs-3921	56	3	with	with	ADP
gs-3921	56	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	56	5	tools	tool	NOUN
gs-3921	56	6	,	,	PUNCT
gs-3921	56	7	patient	patient	NOUN
gs-3921	56	8	-	-	PUNCT
gs-3921	56	9	centered	center	VERB
gs-3921	56	10	care	care	NOUN
gs-3921	56	11	can	can	AUX
gs-3921	56	12	significantly	significantly	ADV
gs-3921	56	13	enhance	enhance	VERB
gs-3921	56	14	the	the	DET
gs-3921	56	15	safety	safety	NOUN
gs-3921	56	16	and	and	CCONJ
gs-3921	56	17	efficacy	efficacy	NOUN
gs-3921	56	18	of	of	ADP
gs-3921	56	19	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	56	20	by	by	ADP
gs-3921	56	21	aligning	align	VERB
gs-3921	56	22	scientific	scientific	ADJ
gs-3921	56	23	precision	precision	NOUN
gs-3921	56	24	with	with	ADP
gs-3921	56	25	humanistic	humanistic	ADJ
gs-3921	56	26	compassion	compassion	NOUN
gs-3921	56	27	.	.	PUNCT
gs-3921	57	1	however	however	ADV
gs-3921	57	2	,	,	PUNCT
gs-3921	57	3	the	the	DET
gs-3921	57	4	clinical	clinical	ADJ
gs-3921	57	5	application	application	NOUN
gs-3921	57	6	of	of	ADP
gs-3921	57	7	these	these	DET
gs-3921	57	8	integrated	integrate	VERB
gs-3921	57	9	approaches	approach	NOUN
gs-3921	57	10	is	be	AUX
gs-3921	57	11	often	often	ADV
gs-3921	57	12	complicated	complicate	VERB
gs-3921	57	13	by	by	ADP
gs-3921	57	14	the	the	DET
gs-3921	57	15	growing	grow	VERB
gs-3921	57	16	incidence	incidence	NOUN
gs-3921	57	17	of	of	ADP
gs-3921	57	18	medication	medication	NOUN
gs-3921	57	19	-	-	PUNCT
gs-3921	57	20	induced	induce	VERB
gs-3921	57	21	adverse	adverse	ADJ
gs-3921	57	22	effects	effect	NOUN
gs-3921	57	23	and	and	CCONJ
gs-3921	57	24	toxicities	toxicity	NOUN
gs-3921	57	25	.	.	PUNCT
gs-3921	58	1	these	these	DET
gs-3921	58	2	adverse	adverse	ADJ
gs-3921	58	3	events	event	NOUN
gs-3921	58	4	are	be	AUX
gs-3921	58	5	not	not	PART
gs-3921	58	6	limited	limit	VERB
gs-3921	58	7	to	to	ADP
gs-3921	58	8	rare	rare	ADJ
gs-3921	58	9	hypersensitivity	hypersensitivity	NOUN
gs-3921	58	10	reactions	reaction	NOUN
gs-3921	58	11	but	but	CCONJ
gs-3921	58	12	span	span	VERB
gs-3921	58	13	a	a	DET
gs-3921	58	14	wide	wide	ADJ
gs-3921	58	15	spectrum	spectrum	NOUN
gs-3921	58	16	including	include	VERB
gs-3921	58	17	dose	dose	NOUN
gs-3921	58	18	-	-	PUNCT
gs-3921	58	19	dependent	dependent	ADJ
gs-3921	58	20	toxicities	toxicity	NOUN
gs-3921	58	21	,	,	PUNCT
gs-3921	58	22	cumulative	cumulative	ADJ
gs-3921	58	23	organ	organ	NOUN
gs-3921	58	24	damage	damage	NOUN
gs-3921	58	25	,	,	PUNCT
gs-3921	58	26	and	and	CCONJ
gs-3921	58	27	unpredictable	unpredictable	ADJ
gs-3921	58	28	idiosyncratic	idiosyncratic	ADJ
gs-3921	58	29	reactions	reaction	NOUN
gs-3921	58	30	.	.	PUNCT
gs-3921	59	1	a	a	DET
gs-3921	59	2	multitude	multitude	NOUN
gs-3921	59	3	of	of	ADP
gs-3921	59	4	drugs	drug	NOUN
gs-3921	59	5	commonly	commonly	ADV
gs-3921	59	6	used	use	VERB
gs-3921	59	7	in	in	ADP
gs-3921	59	8	various	various	ADJ
gs-3921	59	9	therapeutic	therapeutic	ADJ
gs-3921	59	10	categories	category	NOUN
gs-3921	59	11	,	,	PUNCT
gs-3921	59	12	such	such	ADJ
gs-3921	59	13	as	as	ADP
gs-3921	59	14	antimicrobials	antimicrobial	NOUN
gs-3921	59	15	,	,	PUNCT
gs-3921	59	16	anticonvulsants	anticonvulsant	NOUN
gs-3921	59	17	,	,	PUNCT
gs-3921	59	18	immunomodulators	immunomodulator	NOUN
gs-3921	59	19	,	,	PUNCT
gs-3921	59	20	and	and	CCONJ
gs-3921	59	21	chemotherapeutics	chemotherapeutic	NOUN
gs-3921	59	22	,	,	PUNCT
gs-3921	59	23	have	have	AUX
gs-3921	59	24	been	be	AUX
gs-3921	59	25	implicated	implicate	VERB
gs-3921	59	26	in	in	ADP
gs-3921	59	27	causing	cause	VERB
gs-3921	59	28	severe	severe	ADJ
gs-3921	59	29	adverse	adverse	ADJ
gs-3921	59	30	outcomes	outcome	NOUN
gs-3921	59	31	that	that	PRON
gs-3921	59	32	may	may	AUX
gs-3921	59	33	necessitate	necessitate	VERB
gs-3921	59	34	hospitalization	hospitalization	NOUN
gs-3921	59	35	,	,	PUNCT
gs-3921	59	36	lead	lead	VERB
gs-3921	59	37	to	to	ADP
gs-3921	59	38	permanent	permanent	ADJ
gs-3921	59	39	disability	disability	NOUN
gs-3921	59	40	,	,	PUNCT
gs-3921	59	41	or	or	CCONJ
gs-3921	59	42	even	even	ADV
gs-3921	59	43	result	result	VERB
gs-3921	59	44	in	in	ADP
gs-3921	59	45	fatality	fatality	NOUN
gs-3921	59	46	.	.	PUNCT
gs-3921	60	1	the	the	DET
gs-3921	60	2	diversity	diversity	NOUN
gs-3921	60	3	in	in	ADP
gs-3921	60	4	drug	drug	NOUN
gs-3921	60	5	-	-	PUNCT
gs-3921	60	6	induced	induce	VERB
gs-3921	60	7	toxicological	toxicological	ADJ
gs-3921	60	8	profiles	profile	NOUN
gs-3921	60	9	further	far	ADV
gs-3921	60	10	complicates	complicate	VERB
gs-3921	60	11	the	the	DET
gs-3921	60	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	60	13	landscape	landscape	NOUN
gs-3921	60	14	,	,	PUNCT
gs-3921	60	15	demanding	demand	VERB
gs-3921	60	16	a	a	DET
gs-3921	60	17	more	more	ADV
gs-3921	60	18	nuanced	nuanced	ADJ
gs-3921	60	19	understanding	understanding	NOUN
gs-3921	60	20	of	of	ADP
gs-3921	60	21	drug	drug	NOUN
gs-3921	60	22	safety	safety	NOUN
gs-3921	60	23	across	across	ADP
gs-3921	60	24	diverse	diverse	ADJ
gs-3921	60	25	populations	population	NOUN
gs-3921	60	26	.	.	PUNCT
gs-3921	61	1	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	61	2	,	,	PUNCT
gs-3921	61	3	the	the	DET
gs-3921	61	4	systematic	systematic	ADJ
gs-3921	61	5	monitoring	monitoring	NOUN
gs-3921	61	6	and	and	CCONJ
gs-3921	61	7	assessment	assessment	NOUN
gs-3921	61	8	of	of	ADP
gs-3921	61	9	drug	drug	NOUN
gs-3921	61	10	-	-	PUNCT
gs-3921	61	11	related	relate	VERB
gs-3921	61	12	adverse	adverse	ADJ
gs-3921	61	13	events	event	NOUN
gs-3921	61	14	,	,	PUNCT
gs-3921	61	15	represents	represent	VERB
gs-3921	61	16	a	a	DET
gs-3921	61	17	critical	critical	ADJ
gs-3921	61	18	component	component	NOUN
gs-3921	61	19	of	of	ADP
gs-3921	61	20	drug	drug	NOUN
gs-3921	61	21	safety	safety	NOUN
gs-3921	61	22	and	and	CCONJ
gs-3921	61	23	public	public	ADJ
gs-3921	61	24	health	health	NOUN
gs-3921	61	25	surveillance	surveillance	NOUN
gs-3921	61	26	.	.	PUNCT
gs-3921	62	1	although	although	SCONJ
gs-3921	62	2	traditionally	traditionally	ADV
gs-3921	62	3	reactive	reactive	ADJ
gs-3921	62	4	in	in	ADP
gs-3921	62	5	nature	nature	NOUN
gs-3921	62	6	,	,	PUNCT
gs-3921	62	7	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	62	8	is	be	AUX
gs-3921	62	9	now	now	ADV
gs-3921	62	10	undergoing	undergo	VERB
gs-3921	62	11	a	a	DET
gs-3921	62	12	transformative	transformative	ADJ
gs-3921	62	13	shift	shift	NOUN
gs-3921	62	14	toward	toward	ADP
gs-3921	62	15	more	more	ADJ
gs-3921	62	16	proactive	proactive	ADJ
gs-3921	62	17	methodologies	methodology	NOUN
gs-3921	62	18	powered	power	VERB
gs-3921	62	19	by	by	ADP
gs-3921	62	20	data	datum	NOUN
gs-3921	62	21	science	science	NOUN
gs-3921	62	22	,	,	PUNCT
gs-3921	62	23	artificial	artificial	ADJ
gs-3921	62	24	intelligence	intelligence	NOUN
gs-3921	62	25	,	,	PUNCT
gs-3921	62	26	and	and	CCONJ
gs-3921	62	27	real	real	ADJ
gs-3921	62	28	-	-	PUNCT
gs-3921	62	29	world	world	NOUN
gs-3921	62	30	evidence	evidence	NOUN
gs-3921	62	31	.	.	PUNCT
gs-3921	63	1	nonetheless	nonetheless	ADV
gs-3921	63	2	,	,	PUNCT
gs-3921	63	3	numerous	numerous	ADJ
gs-3921	63	4	challenges	challenge	NOUN
gs-3921	63	5	persist	persist	VERB
gs-3921	63	6	in	in	ADP
gs-3921	63	7	this	this	DET
gs-3921	63	8	domain	domain	NOUN
gs-3921	63	9	,	,	PUNCT
gs-3921	63	10	including	include	VERB
gs-3921	63	11	underreporting	underreporte	VERB
gs-3921	63	12	of	of	ADP
gs-3921	63	13	adverse	adverse	ADJ
gs-3921	63	14	events	event	NOUN
gs-3921	63	15	,	,	PUNCT
gs-3921	63	16	lack	lack	NOUN
gs-3921	63	17	of	of	ADP
gs-3921	63	18	standardized	standardized	ADJ
gs-3921	63	19	diagnostic	diagnostic	ADJ
gs-3921	63	20	criteria	criterion	NOUN
gs-3921	63	21	for	for	ADP
gs-3921	63	22	drug	drug	NOUN
gs-3921	63	23	-	-	PUNCT
gs-3921	63	24	induced	induce	VERB
gs-3921	63	25	conditions	condition	NOUN
gs-3921	63	26	,	,	PUNCT
gs-3921	63	27	delayed	delay	VERB
gs-3921	63	28	signal	signal	ADJ
gs-3921	63	29	detection	detection	NOUN
gs-3921	63	30	,	,	PUNCT
gs-3921	63	31	and	and	CCONJ
gs-3921	63	32	fragmented	fragmented	ADJ
gs-3921	63	33	data	datum	NOUN
gs-3921	63	34	systems	system	NOUN
gs-3921	63	35	.	.	PUNCT
gs-3921	64	1	these	these	DET
gs-3921	64	2	limitations	limitation	NOUN
gs-3921	64	3	underscore	underscore	VERB
gs-3921	64	4	the	the	DET
gs-3921	64	5	urgent	urgent	ADJ
gs-3921	64	6	need	need	NOUN
gs-3921	64	7	to	to	PART
gs-3921	64	8	strengthen	strengthen	VERB
gs-3921	64	9	global	global	ADJ
gs-3921	64	10	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	64	11	frameworks	framework	NOUN
gs-3921	64	12	by	by	ADP
gs-3921	64	13	enhancing	enhance	VERB
gs-3921	64	14	collaboration	collaboration	NOUN
gs-3921	64	15	among	among	ADP
gs-3921	64	16	regulatory	regulatory	ADJ
gs-3921	64	17	authorities	authority	NOUN
gs-3921	64	18	,	,	PUNCT
gs-3921	64	19	healthcare	healthcare	NOUN
gs-3921	64	20	providers	provider	NOUN
gs-3921	64	21	,	,	PUNCT
gs-3921	64	22	pharmaceutical	pharmaceutical	ADJ
gs-3921	64	23	companies	company	NOUN
gs-3921	64	24	,	,	PUNCT
gs-3921	64	25	and	and	CCONJ
gs-3921	64	26	patients	patient	NOUN
gs-3921	64	27	themselves	themselves	PRON
gs-3921	64	28	.	.	PUNCT
gs-3921	65	1	the	the	DET
gs-3921	65	2	complexity	complexity	NOUN
gs-3921	65	3	of	of	ADP
gs-3921	65	4	medication	medication	NOUN
gs-3921	65	5	-	-	PUNCT
gs-3921	65	6	induced	induce	VERB
gs-3921	65	7	toxicities	toxicity	NOUN
gs-3921	65	8	is	be	AUX
gs-3921	65	9	further	far	ADV
gs-3921	65	10	deepened	deepen	VERB
gs-3921	65	11	by	by	ADP
gs-3921	65	12	the	the	DET
gs-3921	65	13	presence	presence	NOUN
gs-3921	65	14	of	of	ADP
gs-3921	65	15	multifaceted	multifaceted	ADJ
gs-3921	65	16	risk	risk	NOUN
gs-3921	65	17	determinants	determinant	NOUN
gs-3921	65	18	that	that	PRON
gs-3921	65	19	extend	extend	VERB
gs-3921	65	20	beyond	beyond	ADP
gs-3921	65	21	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	65	22	markers	marker	NOUN
gs-3921	65	23	.	.	PUNCT
gs-3921	66	1	factors	factor	NOUN
gs-3921	66	2	such	such	ADJ
gs-3921	66	3	as	as	ADP
gs-3921	66	4	age	age	NOUN
gs-3921	66	5	,	,	PUNCT
gs-3921	66	6	gender	gender	NOUN
gs-3921	66	7	,	,	PUNCT
gs-3921	66	8	organ	organ	NOUN
gs-3921	66	9	function	function	NOUN
gs-3921	66	10	,	,	PUNCT
gs-3921	66	11	nutritional	nutritional	ADJ
gs-3921	66	12	status	status	NOUN
gs-3921	66	13	,	,	PUNCT
gs-3921	66	14	comorbidities	comorbiditie	NOUN
gs-3921	66	15	,	,	PUNCT
gs-3921	66	16	concomitant	concomitant	ADJ
gs-3921	66	17	drug	drug	NOUN
gs-3921	66	18	use	use	NOUN
gs-3921	66	19	,	,	PUNCT
gs-3921	66	20	and	and	CCONJ
gs-3921	66	21	socioeconomic	socioeconomic	ADJ
gs-3921	66	22	conditions	condition	NOUN
gs-3921	66	23	all	all	PRON
gs-3921	66	24	contribute	contribute	VERB
gs-3921	66	25	to	to	ADP
gs-3921	66	26	the	the	DET
gs-3921	66	27	individual	individual	NOUN
gs-3921	66	28	’s	’s	PART
gs-3921	66	29	susceptibility	susceptibility	NOUN
gs-3921	66	30	to	to	ADP
gs-3921	66	31	adverse	adverse	ADJ
gs-3921	66	32	reactions	reaction	NOUN
gs-3921	66	33	.	.	PUNCT
gs-3921	67	1	environmental	environmental	ADJ
gs-3921	67	2	exposures	exposure	NOUN
gs-3921	67	3	,	,	PUNCT
gs-3921	67	4	drug	drug	NOUN
gs-3921	67	5	-	-	PUNCT
gs-3921	67	6	drug	drug	NOUN
gs-3921	67	7	and	and	CCONJ
gs-3921	67	8	drug	drug	NOUN
gs-3921	67	9	-	-	PUNCT
gs-3921	67	10	food	food	NOUN
gs-3921	67	11	interactions	interaction	NOUN
gs-3921	67	12	,	,	PUNCT
gs-3921	67	13	and	and	CCONJ
gs-3921	67	14	healthcare	healthcare	NOUN
gs-3921	67	15	delivery	delivery	NOUN
gs-3921	67	16	disparities	disparity	NOUN
gs-3921	67	17	also	also	ADV
gs-3921	67	18	influence	influence	VERB
gs-3921	67	19	the	the	DET
gs-3921	67	20	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	67	21	and	and	CCONJ
gs-3921	67	22	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	67	23	of	of	ADP
gs-3921	67	24	medications	medication	NOUN
gs-3921	67	25	in	in	ADP
gs-3921	67	26	unpredictable	unpredictable	ADJ
gs-3921	67	27	ways	way	NOUN
gs-3921	67	28	.	.	PUNCT
gs-3921	68	1	a	a	DET
gs-3921	68	2	comprehensive	comprehensive	ADJ
gs-3921	68	3	understanding	understanding	NOUN
gs-3921	68	4	of	of	ADP
gs-3921	68	5	these	these	DET
gs-3921	68	6	risk	risk	NOUN
gs-3921	68	7	factors	factor	NOUN
gs-3921	68	8	georgian	georgian	PROPN
gs-3921	68	9	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	68	10	მეცნიერები	მეცნიერები	NOUN
gs-3921	68	11	ტ.	ტ.	VERB
gs-3921	68	12	7	7	NUM
gs-3921	68	13	n	n	PRON
gs-3921	68	14	3	3	NUM
gs-3921	68	15	,	,	PUNCT
gs-3921	68	16	2025	2025	NUM
gs-3921	68	17	222	222	NUM
gs-3921	68	18	is	be	AUX
gs-3921	68	19	imperative	imperative	ADJ
gs-3921	68	20	not	not	PART
gs-3921	68	21	only	only	ADV
gs-3921	68	22	for	for	ADP
gs-3921	68	23	preventing	prevent	VERB
gs-3921	68	24	adverse	adverse	ADJ
gs-3921	68	25	outcomes	outcome	NOUN
gs-3921	68	26	but	but	CCONJ
gs-3921	68	27	also	also	ADV
gs-3921	68	28	for	for	ADP
gs-3921	68	29	designing	design	VERB
gs-3921	68	30	targeted	target	VERB
gs-3921	68	31	intervention	intervention	NOUN
gs-3921	68	32	strategies	strategy	NOUN
gs-3921	68	33	that	that	PRON
gs-3921	68	34	are	be	AUX
gs-3921	68	35	both	both	PRON
gs-3921	68	36	context	context	NOUN
gs-3921	68	37	-	-	PUNCT
gs-3921	68	38	sensitive	sensitive	ADJ
gs-3921	68	39	and	and	CCONJ
gs-3921	68	40	population	population	NOUN
gs-3921	68	41	-	-	PUNCT
gs-3921	68	42	specific	specific	NOUN
gs-3921	68	43	.	.	PUNCT
gs-3921	69	1	to	to	PART
gs-3921	69	2	effectively	effectively	ADV
gs-3921	69	3	address	address	VERB
gs-3921	69	4	these	these	DET
gs-3921	69	5	interwoven	interwoven	ADJ
gs-3921	69	6	challenges	challenge	NOUN
gs-3921	69	7	,	,	PUNCT
gs-3921	69	8	the	the	DET
gs-3921	69	9	development	development	NOUN
gs-3921	69	10	of	of	ADP
gs-3921	69	11	strategic	strategic	ADJ
gs-3921	69	12	approaches	approach	NOUN
gs-3921	69	13	to	to	ADP
gs-3921	69	14	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	69	15	management	management	NOUN
gs-3921	69	16	has	have	AUX
gs-3921	69	17	become	become	VERB
gs-3921	69	18	a	a	DET
gs-3921	69	19	priority	priority	NOUN
gs-3921	69	20	within	within	ADP
gs-3921	69	21	both	both	CCONJ
gs-3921	69	22	clinical	clinical	ADJ
gs-3921	69	23	and	and	CCONJ
gs-3921	69	24	research	research	NOUN
gs-3921	69	25	domains	domain	NOUN
gs-3921	69	26	.	.	PUNCT
gs-3921	70	1	these	these	DET
gs-3921	70	2	strategies	strategy	NOUN
gs-3921	70	3	must	must	AUX
gs-3921	70	4	encompass	encompass	VERB
gs-3921	70	5	the	the	DET
gs-3921	70	6	full	full	ADJ
gs-3921	70	7	continuum	continuum	NOUN
gs-3921	70	8	of	of	ADP
gs-3921	70	9	care	care	NOUN
gs-3921	70	10	,	,	PUNCT
gs-3921	70	11	from	from	ADP
gs-3921	70	12	pre	pre	ADJ
gs-3921	70	13	-	-	ADJ
gs-3921	70	14	treatment	treatment	ADJ
gs-3921	70	15	screening	screening	NOUN
gs-3921	70	16	and	and	CCONJ
gs-3921	70	17	drug	drug	NOUN
gs-3921	70	18	selection	selection	NOUN
gs-3921	70	19	to	to	ADP
gs-3921	70	20	therapeutic	therapeutic	ADJ
gs-3921	70	21	monitoring	monitoring	NOUN
gs-3921	70	22	and	and	CCONJ
gs-3921	70	23	post	post	ADJ
gs-3921	70	24	-	-	ADJ
gs-3921	70	25	marketing	marketing	ADJ
gs-3921	70	26	surveillance	surveillance	NOUN
gs-3921	70	27	.	.	PUNCT
gs-3921	71	1	the	the	DET
gs-3921	71	2	implementation	implementation	NOUN
gs-3921	71	3	of	of	ADP
gs-3921	71	4	clinical	clinical	ADJ
gs-3921	71	5	decision	decision	NOUN
gs-3921	71	6	support	support	NOUN
gs-3921	71	7	systems	system	NOUN
gs-3921	71	8	,	,	PUNCT
gs-3921	71	9	electronic	electronic	ADJ
gs-3921	71	10	health	health	NOUN
gs-3921	71	11	records	record	NOUN
gs-3921	71	12	with	with	ADP
gs-3921	71	13	integrated	integrate	VERB
gs-3921	71	14	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	71	15	modules	module	NOUN
gs-3921	71	16	,	,	PUNCT
gs-3921	71	17	and	and	CCONJ
gs-3921	71	18	interdisciplinary	interdisciplinary	ADJ
gs-3921	71	19	care	care	NOUN
gs-3921	71	20	models	model	NOUN
gs-3921	71	21	can	can	AUX
gs-3921	71	22	facilitate	facilitate	VERB
gs-3921	71	23	more	more	ADV
gs-3921	71	24	informed	informed	ADJ
gs-3921	71	25	and	and	CCONJ
gs-3921	71	26	adaptive	adaptive	ADJ
gs-3921	71	27	prescribing	prescribing	NOUN
gs-3921	71	28	practices	practice	NOUN
gs-3921	71	29	.	.	PUNCT
gs-3921	72	1	moreover	moreover	ADV
gs-3921	72	2	,	,	PUNCT
gs-3921	72	3	ongoing	ongoing	ADJ
gs-3921	72	4	education	education	NOUN
gs-3921	72	5	and	and	CCONJ
gs-3921	72	6	training	training	NOUN
gs-3921	72	7	of	of	ADP
gs-3921	72	8	healthcare	healthcare	NOUN
gs-3921	72	9	professionals	professional	NOUN
gs-3921	72	10	in	in	ADP
gs-3921	72	11	the	the	DET
gs-3921	72	12	domains	domain	NOUN
gs-3921	72	13	of	of	ADP
gs-3921	72	14	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	72	15	,	,	PUNCT
gs-3921	72	16	toxicology	toxicology	NOUN
gs-3921	72	17	,	,	PUNCT
gs-3921	72	18	and	and	CCONJ
gs-3921	72	19	personalized	personalized	ADJ
gs-3921	72	20	medicine	medicine	NOUN
gs-3921	72	21	are	be	AUX
gs-3921	72	22	essential	essential	ADJ
gs-3921	72	23	for	for	ADP
gs-3921	72	24	fostering	foster	VERB
gs-3921	72	25	a	a	DET
gs-3921	72	26	culture	culture	NOUN
gs-3921	72	27	of	of	ADP
gs-3921	72	28	safety	safety	NOUN
gs-3921	72	29	and	and	CCONJ
gs-3921	72	30	innovation	innovation	NOUN
gs-3921	72	31	within	within	ADP
gs-3921	72	32	the	the	DET
gs-3921	72	33	healthcare	healthcare	NOUN
gs-3921	72	34	system	system	NOUN
gs-3921	72	35	.	.	PUNCT
gs-3921	73	1	the	the	DET
gs-3921	73	2	scientific	scientific	ADJ
gs-3921	73	3	discourse	discourse	NOUN
gs-3921	73	4	on	on	ADP
gs-3921	73	5	this	this	DET
gs-3921	73	6	topic	topic	NOUN
gs-3921	73	7	is	be	AUX
gs-3921	73	8	therefore	therefore	ADV
gs-3921	73	9	multifaceted	multifaceted	ADJ
gs-3921	73	10	and	and	CCONJ
gs-3921	73	11	requires	require	VERB
gs-3921	73	12	a	a	DET
gs-3921	73	13	thorough	thorough	ADJ
gs-3921	73	14	analysis	analysis	NOUN
gs-3921	73	15	of	of	ADP
gs-3921	73	16	the	the	DET
gs-3921	73	17	interplay	interplay	NOUN
gs-3921	73	18	between	between	ADP
gs-3921	73	19	genetic	genetic	ADJ
gs-3921	73	20	,	,	PUNCT
gs-3921	73	21	clinical	clinical	ADJ
gs-3921	73	22	,	,	PUNCT
gs-3921	73	23	environmental	environmental	ADJ
gs-3921	73	24	,	,	PUNCT
gs-3921	73	25	and	and	CCONJ
gs-3921	73	26	societal	societal	ADJ
gs-3921	73	27	factors	factor	NOUN
gs-3921	73	28	that	that	PRON
gs-3921	73	29	influence	influence	VERB
gs-3921	73	30	drug	drug	NOUN
gs-3921	73	31	safety	safety	NOUN
gs-3921	73	32	and	and	CCONJ
gs-3921	73	33	efficacy	efficacy	NOUN
gs-3921	73	34	.	.	PUNCT
gs-3921	74	1	this	this	DET
gs-3921	74	2	comprehensive	comprehensive	ADJ
gs-3921	74	3	investigation	investigation	NOUN
gs-3921	74	4	not	not	PART
gs-3921	74	5	only	only	ADV
gs-3921	74	6	seeks	seek	VERB
gs-3921	74	7	to	to	PART
gs-3921	74	8	identify	identify	VERB
gs-3921	74	9	the	the	DET
gs-3921	74	10	implicated	implicated	ADJ
gs-3921	74	11	drugs	drug	NOUN
gs-3921	74	12	and	and	CCONJ
gs-3921	74	13	mechanisms	mechanism	NOUN
gs-3921	74	14	underlying	underlie	VERB
gs-3921	74	15	medication	medication	NOUN
gs-3921	74	16	-	-	PUNCT
gs-3921	74	17	induced	induce	VERB
gs-3921	74	18	toxicities	toxicity	NOUN
gs-3921	74	19	but	but	CCONJ
gs-3921	74	20	also	also	ADV
gs-3921	74	21	aims	aim	VERB
gs-3921	74	22	to	to	PART
gs-3921	74	23	critically	critically	ADV
gs-3921	74	24	evaluate	evaluate	VERB
gs-3921	74	25	the	the	DET
gs-3921	74	26	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	74	27	infrastructure	infrastructure	NOUN
gs-3921	74	28	,	,	PUNCT
gs-3921	74	29	patient	patient	ADJ
gs-3921	74	30	engagement	engagement	NOUN
gs-3921	74	31	models	model	NOUN
gs-3921	74	32	,	,	PUNCT
gs-3921	74	33	and	and	CCONJ
gs-3921	74	34	clinical	clinical	ADJ
gs-3921	74	35	implementation	implementation	NOUN
gs-3921	74	36	pathways	pathway	NOUN
gs-3921	74	37	that	that	PRON
gs-3921	74	38	can	can	AUX
gs-3921	74	39	collectively	collectively	ADV
gs-3921	74	40	reduce	reduce	VERB
gs-3921	74	41	the	the	DET
gs-3921	74	42	burden	burden	NOUN
gs-3921	74	43	of	of	ADP
gs-3921	74	44	adverse	adverse	ADJ
gs-3921	74	45	drug	drug	NOUN
gs-3921	74	46	events	event	NOUN
gs-3921	74	47	.	.	PUNCT
gs-3921	75	1	in	in	ADP
gs-3921	75	2	this	this	DET
gs-3921	75	3	context	context	NOUN
gs-3921	75	4	,	,	PUNCT
gs-3921	75	5	the	the	DET
gs-3921	75	6	harmonization	harmonization	NOUN
gs-3921	75	7	of	of	ADP
gs-3921	75	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	75	9	research	research	NOUN
gs-3921	75	10	,	,	PUNCT
gs-3921	75	11	patient	patient	NOUN
gs-3921	75	12	-	-	PUNCT
gs-3921	75	13	centered	center	VERB
gs-3921	75	14	care	care	NOUN
gs-3921	75	15	principles	principle	NOUN
gs-3921	75	16	,	,	PUNCT
gs-3921	75	17	and	and	CCONJ
gs-3921	75	18	real	real	ADJ
gs-3921	75	19	-	-	PUNCT
gs-3921	75	20	world	world	NOUN
gs-3921	75	21	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	75	22	data	datum	NOUN
gs-3921	75	23	emerges	emerge	VERB
gs-3921	75	24	as	as	ADP
gs-3921	75	25	a	a	DET
gs-3921	75	26	powerful	powerful	ADJ
gs-3921	75	27	strategy	strategy	NOUN
gs-3921	75	28	to	to	PART
gs-3921	75	29	optimize	optimize	VERB
gs-3921	75	30	therapeutic	therapeutic	ADJ
gs-3921	75	31	outcomes	outcome	NOUN
gs-3921	75	32	and	and	CCONJ
gs-3921	75	33	promote	promote	VERB
gs-3921	75	34	a	a	DET
gs-3921	75	35	safer	safe	ADJ
gs-3921	75	36	,	,	PUNCT
gs-3921	75	37	more	more	ADV
gs-3921	75	38	responsive	responsive	ADJ
gs-3921	75	39	healthcare	healthcare	NOUN
gs-3921	75	40	environment	environment	NOUN
gs-3921	75	41	.	.	PUNCT
gs-3921	76	1	this	this	DET
gs-3921	76	2	scientific	scientific	ADJ
gs-3921	76	3	exploration	exploration	NOUN
gs-3921	76	4	draws	draw	VERB
gs-3921	76	5	upon	upon	SCONJ
gs-3921	76	6	a	a	DET
gs-3921	76	7	wide	wide	ADJ
gs-3921	76	8	array	array	NOUN
gs-3921	76	9	of	of	ADP
gs-3921	76	10	interdisciplinary	interdisciplinary	ADJ
gs-3921	76	11	sources	source	NOUN
gs-3921	76	12	,	,	PUNCT
gs-3921	76	13	encompassing	encompass	VERB
gs-3921	76	14	molecular	molecular	ADJ
gs-3921	76	15	pharmacology	pharmacology	NOUN
gs-3921	76	16	,	,	PUNCT
gs-3921	76	17	clinical	clinical	ADJ
gs-3921	76	18	genetics	genetic	NOUN
gs-3921	76	19	,	,	PUNCT
gs-3921	76	20	toxicological	toxicological	ADJ
gs-3921	76	21	research	research	NOUN
gs-3921	76	22	,	,	PUNCT
gs-3921	76	23	regulatory	regulatory	ADJ
gs-3921	76	24	science	science	NOUN
gs-3921	76	25	,	,	PUNCT
gs-3921	76	26	and	and	CCONJ
gs-3921	76	27	health	health	NOUN
gs-3921	76	28	policy	policy	NOUN
gs-3921	76	29	.	.	PUNCT
gs-3921	77	1	it	it	PRON
gs-3921	77	2	endeavors	endeavor	VERB
gs-3921	77	3	to	to	PART
gs-3921	77	4	illuminate	illuminate	VERB
gs-3921	77	5	the	the	DET
gs-3921	77	6	translational	translational	ADJ
gs-3921	77	7	potential	potential	NOUN
gs-3921	77	8	of	of	ADP
gs-3921	77	9	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	77	10	findings	finding	NOUN
gs-3921	77	11	in	in	ADP
gs-3921	77	12	real	real	ADJ
gs-3921	77	13	-	-	PUNCT
gs-3921	77	14	world	world	NOUN
gs-3921	77	15	settings	setting	NOUN
gs-3921	77	16	,	,	PUNCT
gs-3921	77	17	assess	assess	VERB
gs-3921	77	18	the	the	DET
gs-3921	77	19	barriers	barrier	NOUN
gs-3921	77	20	to	to	ADP
gs-3921	77	21	clinical	clinical	ADJ
gs-3921	77	22	adoption	adoption	NOUN
gs-3921	77	23	of	of	ADP
gs-3921	77	24	precision	precision	NOUN
gs-3921	77	25	medicine	medicine	NOUN
gs-3921	77	26	tools	tool	NOUN
gs-3921	77	27	,	,	PUNCT
gs-3921	77	28	and	and	CCONJ
gs-3921	77	29	propose	propose	VERB
gs-3921	77	30	actionable	actionable	ADJ
gs-3921	77	31	recommendations	recommendation	NOUN
gs-3921	77	32	for	for	ADP
gs-3921	77	33	future	future	ADJ
gs-3921	77	34	research	research	NOUN
gs-3921	77	35	and	and	CCONJ
gs-3921	77	36	practice	practice	NOUN
gs-3921	77	37	.	.	PUNCT
gs-3921	78	1	special	special	ADJ
gs-3921	78	2	emphasis	emphasis	NOUN
gs-3921	78	3	is	be	AUX
gs-3921	78	4	placed	place	VERB
gs-3921	78	5	on	on	ADP
gs-3921	78	6	the	the	DET
gs-3921	78	7	identification	identification	NOUN
gs-3921	78	8	of	of	ADP
gs-3921	78	9	high	high	ADJ
gs-3921	78	10	-	-	PUNCT
gs-3921	78	11	risk	risk	NOUN
gs-3921	78	12	populations	population	NOUN
gs-3921	78	13	,	,	PUNCT
gs-3921	78	14	elucidation	elucidation	NOUN
gs-3921	78	15	of	of	ADP
gs-3921	78	16	gene	gene	NOUN
gs-3921	78	17	-	-	PUNCT
gs-3921	78	18	drug	drug	NOUN
gs-3921	78	19	interactions	interaction	NOUN
gs-3921	78	20	,	,	PUNCT
gs-3921	78	21	refinement	refinement	NOUN
gs-3921	78	22	of	of	ADP
gs-3921	78	23	adverse	adverse	ADJ
gs-3921	78	24	event	event	NOUN
gs-3921	78	25	reporting	report	VERB
gs-3921	78	26	systems	system	NOUN
gs-3921	78	27	,	,	PUNCT
gs-3921	78	28	and	and	CCONJ
gs-3921	78	29	promotion	promotion	NOUN
gs-3921	78	30	of	of	ADP
gs-3921	78	31	evidence	evidence	NOUN
gs-3921	78	32	-	-	PUNCT
gs-3921	78	33	based	base	VERB
gs-3921	78	34	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	78	35	guidelines	guideline	NOUN
gs-3921	78	36	.	.	PUNCT
gs-3921	79	1	through	through	ADP
gs-3921	79	2	this	this	DET
gs-3921	79	3	integrative	integrative	ADJ
gs-3921	79	4	lens	len	NOUN
gs-3921	79	5	,	,	PUNCT
gs-3921	79	6	the	the	DET
gs-3921	79	7	discourse	discourse	NOUN
gs-3921	79	8	aspires	aspire	VERB
gs-3921	79	9	to	to	PART
gs-3921	79	10	contribute	contribute	VERB
gs-3921	79	11	meaningfully	meaningfully	ADV
gs-3921	79	12	to	to	ADP
gs-3921	79	13	the	the	DET
gs-3921	79	14	global	global	ADJ
gs-3921	79	15	endeavor	endeavor	NOUN
gs-3921	79	16	of	of	ADP
gs-3921	79	17	enhancing	enhance	VERB
gs-3921	79	18	medication	medication	NOUN
gs-3921	79	19	safety	safety	NOUN
gs-3921	79	20	and	and	CCONJ
gs-3921	79	21	therapeutic	therapeutic	ADJ
gs-3921	79	22	effectiveness	effectiveness	NOUN
gs-3921	79	23	across	across	ADP
gs-3921	79	24	all	all	DET
gs-3921	79	25	domains	domain	NOUN
gs-3921	79	26	of	of	ADP
gs-3921	79	27	healthcare	healthcare	PROPN
gs-3921	79	28	.	.	PUNCT
gs-3921	80	1	as	as	SCONJ
gs-3921	80	2	the	the	DET
gs-3921	80	3	burden	burden	NOUN
gs-3921	80	4	of	of	ADP
gs-3921	80	5	medication	medication	NOUN
gs-3921	80	6	-	-	PUNCT
gs-3921	80	7	induced	induce	VERB
gs-3921	80	8	adverse	adverse	ADJ
gs-3921	80	9	effects	effect	NOUN
gs-3921	80	10	continues	continue	VERB
gs-3921	80	11	to	to	PART
gs-3921	80	12	rise	rise	VERB
gs-3921	80	13	in	in	ADP
gs-3921	80	14	both	both	CCONJ
gs-3921	80	15	highincome	highincome	ADJ
gs-3921	80	16	and	and	CCONJ
gs-3921	80	17	resource	resource	NOUN
gs-3921	80	18	-	-	PUNCT
gs-3921	80	19	limited	limit	VERB
gs-3921	80	20	settings	setting	NOUN
gs-3921	80	21	,	,	PUNCT
gs-3921	80	22	the	the	DET
gs-3921	80	23	imperative	imperative	NOUN
gs-3921	80	24	for	for	ADP
gs-3921	80	25	a	a	DET
gs-3921	80	26	paradigm	paradigm	NOUN
gs-3921	80	27	shift	shift	NOUN
gs-3921	80	28	toward	toward	ADP
gs-3921	80	29	anticipatory	anticipatory	ADJ
gs-3921	80	30	,	,	PUNCT
gs-3921	80	31	individualized	individualized	ADJ
gs-3921	80	32	,	,	PUNCT
gs-3921	80	33	and	and	CCONJ
gs-3921	80	34	systemically	systemically	ADV
gs-3921	80	35	integrated	integrate	VERB
gs-3921	80	36	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	80	37	becomes	become	VERB
gs-3921	80	38	increasingly	increasingly	ADV
gs-3921	80	39	clear	clear	ADJ
gs-3921	80	40	.	.	PUNCT
gs-3921	81	1	by	by	ADP
gs-3921	81	2	advancing	advance	VERB
gs-3921	81	3	the	the	DET
gs-3921	81	4	scientific	scientific	ADJ
gs-3921	81	5	conversation	conversation	NOUN
gs-3921	81	6	around	around	ADP
gs-3921	81	7	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	81	8	,	,	PUNCT
gs-3921	81	9	patient	patient	NOUN
gs-3921	81	10	-	-	PUNCT
gs-3921	81	11	centered	center	VERB
gs-3921	81	12	models	model	NOUN
gs-3921	81	13	,	,	PUNCT
gs-3921	81	14	and	and	CCONJ
gs-3921	81	15	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	81	16	,	,	PUNCT
gs-3921	81	17	this	this	DET
gs-3921	81	18	investigation	investigation	NOUN
gs-3921	81	19	aims	aim	VERB
gs-3921	81	20	to	to	PART
gs-3921	81	21	chart	chart	VERB
gs-3921	81	22	a	a	DET
gs-3921	81	23	course	course	NOUN
gs-3921	81	24	toward	toward	ADP
gs-3921	81	25	more	more	ADV
gs-3921	81	26	personalized	personalized	ADJ
gs-3921	81	27	,	,	PUNCT
gs-3921	81	28	equitable	equitable	ADJ
gs-3921	81	29	,	,	PUNCT
gs-3921	81	30	and	and	CCONJ
gs-3921	81	31	safe	safe	ADJ
gs-3921	81	32	medication	medication	NOUN
gs-3921	81	33	use	use	NOUN
gs-3921	81	34	for	for	ADP
gs-3921	81	35	all	all	DET
gs-3921	81	36	patients	patient	NOUN
gs-3921	81	37	,	,	PUNCT
gs-3921	81	38	regardless	regardless	ADV
gs-3921	81	39	of	of	ADP
gs-3921	81	40	genetic	genetic	ADJ
gs-3921	81	41	background	background	NOUN
gs-3921	81	42	,	,	PUNCT
gs-3921	81	43	clinical	clinical	ADJ
gs-3921	81	44	complexity	complexity	NOUN
gs-3921	81	45	,	,	PUNCT
gs-3921	81	46	or	or	CCONJ
gs-3921	81	47	healthcare	healthcare	NOUN
gs-3921	81	48	access	access	NOUN
gs-3921	81	49	.	.	PUNCT
gs-3921	82	1	georgian	georgian	ADJ
gs-3921	82	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	82	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	82	4	ტ.	ტ.	VERB
gs-3921	82	5	7	7	NUM
gs-3921	82	6	n	n	PRON
gs-3921	82	7	3	3	NUM
gs-3921	82	8	,	,	PUNCT
gs-3921	82	9	2025	2025	NUM
gs-3921	82	10	223	223	NUM
gs-3921	82	11	the	the	DET
gs-3921	82	12	evolution	evolution	NOUN
gs-3921	82	13	of	of	ADP
gs-3921	82	14	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	82	15	from	from	ADP
gs-3921	82	16	a	a	DET
gs-3921	82	17	niche	niche	NOUN
gs-3921	82	18	scientific	scientific	ADJ
gs-3921	82	19	interest	interest	NOUN
gs-3921	82	20	into	into	ADP
gs-3921	82	21	a	a	DET
gs-3921	82	22	central	central	ADJ
gs-3921	82	23	component	component	NOUN
gs-3921	82	24	of	of	ADP
gs-3921	82	25	personalized	personalized	ADJ
gs-3921	82	26	medicine	medicine	NOUN
gs-3921	82	27	reflects	reflect	VERB
gs-3921	82	28	the	the	DET
gs-3921	82	29	maturation	maturation	NOUN
gs-3921	82	30	of	of	ADP
gs-3921	82	31	biomedical	biomedical	ADJ
gs-3921	82	32	knowledge	knowledge	NOUN
gs-3921	82	33	and	and	CCONJ
gs-3921	82	34	its	its	PRON
gs-3921	82	35	translation	translation	NOUN
gs-3921	82	36	into	into	ADP
gs-3921	82	37	clinical	clinical	ADJ
gs-3921	82	38	utility	utility	NOUN
gs-3921	82	39	.	.	PUNCT
gs-3921	83	1	with	with	ADP
gs-3921	83	2	advances	advance	NOUN
gs-3921	83	3	in	in	ADP
gs-3921	83	4	high	high	ADJ
gs-3921	83	5	-	-	PUNCT
gs-3921	83	6	throughput	throughput	NOUN
gs-3921	83	7	genomic	genomic	NOUN
gs-3921	83	8	technologies	technology	NOUN
gs-3921	83	9	and	and	CCONJ
gs-3921	83	10	bioinformatics	bioinformatic	NOUN
gs-3921	83	11	,	,	PUNCT
gs-3921	83	12	the	the	DET
gs-3921	83	13	identification	identification	NOUN
gs-3921	83	14	of	of	ADP
gs-3921	83	15	clinically	clinically	ADV
gs-3921	83	16	relevant	relevant	ADJ
gs-3921	83	17	single	single	ADJ
gs-3921	83	18	nucleotide	nucleotide	ADJ
gs-3921	83	19	polymorphisms	polymorphism	NOUN
gs-3921	83	20	(	(	PUNCT
gs-3921	83	21	snps	snps	PROPN
gs-3921	83	22	)	)	PUNCT
gs-3921	83	23	,	,	PUNCT
gs-3921	83	24	copy	copy	VERB
gs-3921	83	25	number	number	NOUN
gs-3921	83	26	variations	variation	NOUN
gs-3921	83	27	,	,	PUNCT
gs-3921	83	28	and	and	CCONJ
gs-3921	83	29	haplotypes	haplotype	NOUN
gs-3921	83	30	has	have	AUX
gs-3921	83	31	become	become	VERB
gs-3921	83	32	increasingly	increasingly	ADV
gs-3921	83	33	accessible	accessible	ADJ
gs-3921	83	34	and	and	CCONJ
gs-3921	83	35	affordable	affordable	ADJ
gs-3921	83	36	.	.	PUNCT
gs-3921	84	1	these	these	DET
gs-3921	84	2	genomic	genomic	ADJ
gs-3921	84	3	markers	marker	NOUN
gs-3921	84	4	provide	provide	VERB
gs-3921	84	5	clinicians	clinician	NOUN
gs-3921	84	6	with	with	ADP
gs-3921	84	7	predictive	predictive	ADJ
gs-3921	84	8	information	information	NOUN
gs-3921	84	9	about	about	ADP
gs-3921	84	10	an	an	DET
gs-3921	84	11	individual	individual	NOUN
gs-3921	84	12	’s	’s	PART
gs-3921	84	13	capacity	capacity	NOUN
gs-3921	84	14	to	to	PART
gs-3921	84	15	metabolize	metabolize	VERB
gs-3921	84	16	,	,	PUNCT
gs-3921	84	17	activate	activate	VERB
gs-3921	84	18	,	,	PUNCT
gs-3921	84	19	deactivate	deactivate	VERB
gs-3921	84	20	,	,	PUNCT
gs-3921	84	21	or	or	CCONJ
gs-3921	84	22	transport	transport	NOUN
gs-3921	84	23	drugs	drug	NOUN
gs-3921	84	24	,	,	PUNCT
gs-3921	84	25	thus	thus	ADV
gs-3921	84	26	informing	inform	VERB
gs-3921	84	27	therapeutic	therapeutic	ADJ
gs-3921	84	28	decisions	decision	NOUN
gs-3921	84	29	with	with	ADP
gs-3921	84	30	unprecedented	unprecedented	ADJ
gs-3921	84	31	precision	precision	NOUN
gs-3921	84	32	.	.	PUNCT
gs-3921	85	1	polymorphisms	polymorphism	NOUN
gs-3921	85	2	in	in	ADP
gs-3921	85	3	genes	gene	NOUN
gs-3921	85	4	encoding	encode	VERB
gs-3921	85	5	cytochrome	cytochrome	ADJ
gs-3921	85	6	p450	p450	NUM
gs-3921	85	7	enzymes	enzyme	NOUN
gs-3921	85	8	,	,	PUNCT
gs-3921	85	9	udp	udp	NOUN
gs-3921	85	10	-	-	NOUN
gs-3921	85	11	glucuronosyltransferases	glucuronosyltransferase	NOUN
gs-3921	85	12	,	,	PUNCT
gs-3921	85	13	drug	drug	NOUN
gs-3921	85	14	transporters	transporter	NOUN
gs-3921	85	15	such	such	ADJ
gs-3921	85	16	as	as	ADP
gs-3921	85	17	abcb1	abcb1	NOUN
gs-3921	85	18	and	and	CCONJ
gs-3921	85	19	slco1b1	slco1b1	CCONJ
gs-3921	85	20	,	,	PUNCT
gs-3921	85	21	and	and	CCONJ
gs-3921	85	22	targets	target	NOUN
gs-3921	85	23	like	like	ADP
gs-3921	85	24	vkorc1	vkorc1	NOUN
gs-3921	85	25	and	and	CCONJ
gs-3921	85	26	hla	hla	NOUN
gs-3921	85	27	alleles	allele	NOUN
gs-3921	85	28	have	have	AUX
gs-3921	85	29	been	be	AUX
gs-3921	85	30	associated	associate	VERB
gs-3921	85	31	with	with	ADP
gs-3921	85	32	altered	altered	ADJ
gs-3921	85	33	drug	drug	NOUN
gs-3921	85	34	responses	response	NOUN
gs-3921	85	35	and	and	CCONJ
gs-3921	85	36	risk	risk	NOUN
gs-3921	85	37	of	of	ADP
gs-3921	85	38	toxicity	toxicity	NOUN
gs-3921	85	39	.	.	PUNCT
gs-3921	86	1	for	for	ADP
gs-3921	86	2	example	example	NOUN
gs-3921	86	3	,	,	PUNCT
gs-3921	86	4	variations	variation	NOUN
gs-3921	86	5	in	in	ADP
gs-3921	86	6	cyp2d6	cyp2d6	NOUN
gs-3921	86	7	can	can	AUX
gs-3921	86	8	affect	affect	VERB
gs-3921	86	9	the	the	DET
gs-3921	86	10	metabolism	metabolism	NOUN
gs-3921	86	11	of	of	ADP
gs-3921	86	12	antidepressants	antidepressant	NOUN
gs-3921	86	13	,	,	PUNCT
gs-3921	86	14	opioids	opioid	NOUN
gs-3921	86	15	,	,	PUNCT
gs-3921	86	16	and	and	CCONJ
gs-3921	86	17	antiarrhythmics	antiarrhythmic	NOUN
gs-3921	86	18	,	,	PUNCT
gs-3921	86	19	while	while	SCONJ
gs-3921	86	20	polymorphisms	polymorphism	NOUN
gs-3921	86	21	in	in	ADP
gs-3921	86	22	tpmt	tpmt	NOUN
gs-3921	86	23	influence	influence	NOUN
gs-3921	86	24	thiopurine	thiopurine	NOUN
gs-3921	86	25	tolerance	tolerance	NOUN
gs-3921	86	26	.	.	PUNCT
gs-3921	87	1	despite	despite	SCONJ
gs-3921	87	2	these	these	DET
gs-3921	87	3	advancements	advancement	NOUN
gs-3921	87	4	,	,	PUNCT
gs-3921	87	5	the	the	DET
gs-3921	87	6	clinical	clinical	ADJ
gs-3921	87	7	translation	translation	NOUN
gs-3921	87	8	of	of	ADP
gs-3921	87	9	genomic	genomic	ADJ
gs-3921	87	10	information	information	NOUN
gs-3921	87	11	into	into	ADP
gs-3921	87	12	everyday	everyday	ADJ
gs-3921	87	13	practice	practice	NOUN
gs-3921	87	14	remains	remain	VERB
gs-3921	87	15	incomplete	incomplete	ADJ
gs-3921	87	16	,	,	PUNCT
gs-3921	87	17	highlighting	highlight	VERB
gs-3921	87	18	the	the	DET
gs-3921	87	19	gap	gap	NOUN
gs-3921	87	20	between	between	ADP
gs-3921	87	21	scientific	scientific	ADJ
gs-3921	87	22	discovery	discovery	NOUN
gs-3921	87	23	and	and	CCONJ
gs-3921	87	24	bedside	bedside	NOUN
gs-3921	87	25	application	application	NOUN
gs-3921	87	26	.	.	PUNCT
gs-3921	88	1	a	a	DET
gs-3921	88	2	central	central	ADJ
gs-3921	88	3	obstacle	obstacle	NOUN
gs-3921	88	4	to	to	ADP
gs-3921	88	5	the	the	DET
gs-3921	88	6	widespread	widespread	ADJ
gs-3921	88	7	adoption	adoption	NOUN
gs-3921	88	8	of	of	ADP
gs-3921	88	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	88	10	testing	testing	NOUN
gs-3921	88	11	is	be	AUX
gs-3921	88	12	the	the	DET
gs-3921	88	13	lack	lack	NOUN
gs-3921	88	14	of	of	ADP
gs-3921	88	15	standardized	standardized	ADJ
gs-3921	88	16	guidelines	guideline	NOUN
gs-3921	88	17	and	and	CCONJ
gs-3921	88	18	integration	integration	NOUN
gs-3921	88	19	into	into	ADP
gs-3921	88	20	existing	exist	VERB
gs-3921	88	21	clinical	clinical	ADJ
gs-3921	88	22	workflows	workflow	NOUN
gs-3921	88	23	.	.	PUNCT
gs-3921	89	1	while	while	SCONJ
gs-3921	89	2	organizations	organization	NOUN
gs-3921	89	3	such	such	ADJ
gs-3921	89	4	as	as	ADP
gs-3921	89	5	the	the	DET
gs-3921	89	6	clinical	clinical	ADJ
gs-3921	89	7	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	89	8	implementation	implementation	NOUN
gs-3921	89	9	consortium	consortium	NOUN
gs-3921	89	10	(	(	PUNCT
gs-3921	89	11	cpic	cpic	NOUN
gs-3921	89	12	)	)	PUNCT
gs-3921	89	13	and	and	CCONJ
gs-3921	89	14	the	the	DET
gs-3921	89	15	dutch	dutch	ADJ
gs-3921	89	16	pharmacogenetics	pharmacogenetics	PROPN
gs-3921	89	17	working	working	PROPN
gs-3921	89	18	group	group	NOUN
gs-3921	89	19	(	(	PUNCT
gs-3921	89	20	dpwg	dpwg	PROPN
gs-3921	89	21	)	)	PUNCT
gs-3921	89	22	have	have	AUX
gs-3921	89	23	developed	develop	VERB
gs-3921	89	24	genotype	genotype	NOUN
gs-3921	89	25	-	-	PUNCT
gs-3921	89	26	based	base	VERB
gs-3921	89	27	dosing	dose	VERB
gs-3921	89	28	guidelines	guideline	NOUN
gs-3921	89	29	,	,	PUNCT
gs-3921	89	30	these	these	DET
gs-3921	89	31	resources	resource	NOUN
gs-3921	89	32	are	be	AUX
gs-3921	89	33	not	not	PART
gs-3921	89	34	universally	universally	ADV
gs-3921	89	35	utilized	utilize	VERB
gs-3921	89	36	or	or	CCONJ
gs-3921	89	37	implemented	implement	VERB
gs-3921	89	38	.	.	PUNCT
gs-3921	90	1	healthcare	healthcare	NOUN
gs-3921	90	2	institutions	institution	NOUN
gs-3921	90	3	often	often	ADV
gs-3921	90	4	lack	lack	VERB
gs-3921	90	5	the	the	DET
gs-3921	90	6	informatics	informatic	NOUN
gs-3921	90	7	infrastructure	infrastructure	NOUN
gs-3921	90	8	,	,	PUNCT
gs-3921	90	9	trained	train	VERB
gs-3921	90	10	personnel	personnel	NOUN
gs-3921	90	11	,	,	PUNCT
gs-3921	90	12	and	and	CCONJ
gs-3921	90	13	reimbursement	reimbursement	NOUN
gs-3921	90	14	mechanisms	mechanism	NOUN
gs-3921	90	15	necessary	necessary	ADJ
gs-3921	90	16	to	to	PART
gs-3921	90	17	support	support	VERB
gs-3921	90	18	routine	routine	ADJ
gs-3921	90	19	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	90	20	testing	testing	NOUN
gs-3921	90	21	.	.	PUNCT
gs-3921	91	1	additionally	additionally	ADV
gs-3921	91	2	,	,	PUNCT
gs-3921	91	3	clinicians	clinician	NOUN
gs-3921	91	4	may	may	AUX
gs-3921	91	5	feel	feel	VERB
gs-3921	91	6	unequipped	unequipped	ADJ
gs-3921	91	7	to	to	PART
gs-3921	91	8	interpret	interpret	VERB
gs-3921	91	9	complex	complex	ADJ
gs-3921	91	10	genetic	genetic	ADJ
gs-3921	91	11	data	datum	NOUN
gs-3921	91	12	or	or	CCONJ
gs-3921	91	13	uncertain	uncertain	ADJ
gs-3921	91	14	about	about	ADP
gs-3921	91	15	its	its	PRON
gs-3921	91	16	clinical	clinical	ADJ
gs-3921	91	17	significance	significance	NOUN
gs-3921	91	18	,	,	PUNCT
gs-3921	91	19	particularly	particularly	ADV
gs-3921	91	20	in	in	ADP
gs-3921	91	21	the	the	DET
gs-3921	91	22	absence	absence	NOUN
gs-3921	91	23	of	of	ADP
gs-3921	91	24	large	large	ADJ
gs-3921	91	25	-	-	PUNCT
gs-3921	91	26	scale	scale	NOUN
gs-3921	91	27	validation	validation	NOUN
gs-3921	91	28	studies	study	NOUN
gs-3921	91	29	across	across	ADP
gs-3921	91	30	diverse	diverse	ADJ
gs-3921	91	31	populations	population	NOUN
gs-3921	91	32	.	.	PUNCT
gs-3921	92	1	these	these	DET
gs-3921	92	2	limitations	limitation	NOUN
gs-3921	92	3	are	be	AUX
gs-3921	92	4	further	far	ADV
gs-3921	92	5	compounded	compound	VERB
gs-3921	92	6	by	by	ADP
gs-3921	92	7	disparities	disparity	NOUN
gs-3921	92	8	in	in	ADP
gs-3921	92	9	access	access	NOUN
gs-3921	92	10	to	to	ADP
gs-3921	92	11	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	92	12	services	service	NOUN
gs-3921	92	13	,	,	PUNCT
gs-3921	92	14	particularly	particularly	ADV
gs-3921	92	15	in	in	ADP
gs-3921	92	16	lowand	lowand	ADJ
gs-3921	92	17	middle	middle	ADJ
gs-3921	92	18	-	-	PUNCT
gs-3921	92	19	income	income	NOUN
gs-3921	92	20	countries	country	NOUN
gs-3921	92	21	,	,	PUNCT
gs-3921	92	22	where	where	SCONJ
gs-3921	92	23	healthcare	healthcare	NOUN
gs-3921	92	24	resources	resource	NOUN
gs-3921	92	25	are	be	AUX
gs-3921	92	26	often	often	ADV
gs-3921	92	27	limited	limit	VERB
gs-3921	92	28	and	and	CCONJ
gs-3921	92	29	priorities	priority	NOUN
gs-3921	92	30	may	may	AUX
gs-3921	92	31	be	be	AUX
gs-3921	92	32	directed	direct	VERB
gs-3921	92	33	toward	toward	ADP
gs-3921	92	34	more	more	ADV
gs-3921	92	35	immediate	immediate	ADJ
gs-3921	92	36	public	public	ADJ
gs-3921	92	37	health	health	NOUN
gs-3921	92	38	concerns	concern	NOUN
gs-3921	92	39	.	.	PUNCT
gs-3921	93	1	the	the	DET
gs-3921	93	2	implementation	implementation	NOUN
gs-3921	93	3	of	of	ADP
gs-3921	93	4	patient	patient	NOUN
gs-3921	93	5	-	-	PUNCT
gs-3921	93	6	centered	center	VERB
gs-3921	93	7	care	care	NOUN
gs-3921	93	8	as	as	ADP
gs-3921	93	9	a	a	DET
gs-3921	93	10	guiding	guide	VERB
gs-3921	93	11	philosophy	philosophy	NOUN
gs-3921	93	12	within	within	ADP
gs-3921	93	13	healthcare	healthcare	NOUN
gs-3921	93	14	systems	system	NOUN
gs-3921	93	15	intersects	intersect	NOUN
gs-3921	93	16	powerfully	powerfully	ADV
gs-3921	93	17	with	with	ADP
gs-3921	93	18	the	the	DET
gs-3921	93	19	goals	goal	NOUN
gs-3921	93	20	of	of	ADP
gs-3921	93	21	precision	precision	NOUN
gs-3921	93	22	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	93	23	.	.	PUNCT
gs-3921	94	1	this	this	DET
gs-3921	94	2	model	model	NOUN
gs-3921	94	3	calls	call	VERB
gs-3921	94	4	for	for	ADP
gs-3921	94	5	the	the	DET
gs-3921	94	6	active	active	ADJ
gs-3921	94	7	involvement	involvement	NOUN
gs-3921	94	8	of	of	ADP
gs-3921	94	9	patients	patient	NOUN
gs-3921	94	10	in	in	ADP
gs-3921	94	11	their	their	PRON
gs-3921	94	12	treatment	treatment	NOUN
gs-3921	94	13	decisions	decision	NOUN
gs-3921	94	14	,	,	PUNCT
gs-3921	94	15	recognition	recognition	NOUN
gs-3921	94	16	of	of	ADP
gs-3921	94	17	their	their	PRON
gs-3921	94	18	values	value	NOUN
gs-3921	94	19	and	and	CCONJ
gs-3921	94	20	preferences	preference	NOUN
gs-3921	94	21	,	,	PUNCT
gs-3921	94	22	and	and	CCONJ
gs-3921	94	23	responsiveness	responsiveness	NOUN
gs-3921	94	24	to	to	ADP
gs-3921	94	25	their	their	PRON
gs-3921	94	26	psychosocial	psychosocial	ADJ
gs-3921	94	27	context	context	NOUN
gs-3921	94	28	.	.	PUNCT
gs-3921	95	1	when	when	SCONJ
gs-3921	95	2	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	95	3	information	information	NOUN
gs-3921	95	4	is	be	AUX
gs-3921	95	5	shared	share	VERB
gs-3921	95	6	transparently	transparently	ADV
gs-3921	95	7	with	with	ADP
gs-3921	95	8	patients	patient	NOUN
gs-3921	95	9	,	,	PUNCT
gs-3921	95	10	it	it	PRON
gs-3921	95	11	empowers	empower	VERB
gs-3921	95	12	them	they	PRON
gs-3921	95	13	to	to	PART
gs-3921	95	14	make	make	VERB
gs-3921	95	15	informed	informed	ADJ
gs-3921	95	16	decisions	decision	NOUN
gs-3921	95	17	about	about	ADP
gs-3921	95	18	their	their	PRON
gs-3921	95	19	care	care	NOUN
gs-3921	95	20	and	and	CCONJ
gs-3921	95	21	fosters	foster	VERB
gs-3921	95	22	a	a	DET
gs-3921	95	23	collaborative	collaborative	ADJ
gs-3921	95	24	relationship	relationship	NOUN
gs-3921	95	25	with	with	ADP
gs-3921	95	26	their	their	PRON
gs-3921	95	27	healthcare	healthcare	NOUN
gs-3921	95	28	providers	provider	NOUN
gs-3921	95	29	.	.	PUNCT
gs-3921	96	1	this	this	DET
gs-3921	96	2	collaborative	collaborative	ADJ
gs-3921	96	3	ethos	ethos	NOUN
gs-3921	96	4	extends	extend	VERB
gs-3921	96	5	to	to	ADP
gs-3921	96	6	the	the	DET
gs-3921	96	7	ethical	ethical	ADJ
gs-3921	96	8	dimensions	dimension	NOUN
gs-3921	96	9	of	of	ADP
gs-3921	96	10	genetic	genetic	ADJ
gs-3921	96	11	testing	testing	NOUN
gs-3921	96	12	,	,	PUNCT
gs-3921	96	13	including	include	VERB
gs-3921	96	14	issues	issue	NOUN
gs-3921	96	15	of	of	ADP
gs-3921	96	16	consent	consent	NOUN
gs-3921	96	17	,	,	PUNCT
gs-3921	96	18	confidentiality	confidentiality	NOUN
gs-3921	96	19	,	,	PUNCT
gs-3921	96	20	genetic	genetic	ADJ
gs-3921	96	21	counseling	counseling	NOUN
gs-3921	96	22	,	,	PUNCT
gs-3921	96	23	and	and	CCONJ
gs-3921	96	24	potential	potential	ADJ
gs-3921	96	25	psychosocial	psychosocial	ADJ
gs-3921	96	26	impact	impact	NOUN
gs-3921	96	27	.	.	PUNCT
gs-3921	97	1	ethical	ethical	ADJ
gs-3921	97	2	stewardship	stewardship	NOUN
gs-3921	97	3	of	of	ADP
gs-3921	97	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	97	5	information	information	NOUN
gs-3921	97	6	is	be	AUX
gs-3921	97	7	essential	essential	ADJ
gs-3921	97	8	to	to	PART
gs-3921	97	9	avoid	avoid	VERB
gs-3921	97	10	unintended	unintended	ADJ
gs-3921	97	11	consequences	consequence	NOUN
gs-3921	97	12	such	such	ADJ
gs-3921	97	13	as	as	ADP
gs-3921	97	14	genetic	genetic	ADJ
gs-3921	97	15	discrimination	discrimination	NOUN
gs-3921	97	16	,	,	PUNCT
gs-3921	97	17	privacy	privacy	NOUN
gs-3921	97	18	breaches	breach	NOUN
gs-3921	97	19	,	,	PUNCT
gs-3921	97	20	or	or	CCONJ
gs-3921	97	21	anxiety	anxiety	NOUN
gs-3921	97	22	related	relate	VERB
gs-3921	97	23	to	to	ADP
gs-3921	97	24	genetic	genetic	ADJ
gs-3921	97	25	risk	risk	NOUN
gs-3921	97	26	.	.	PUNCT
gs-3921	98	1	as	as	SCONJ
gs-3921	98	2	such	such	ADJ
gs-3921	98	3	,	,	PUNCT
gs-3921	98	4	patient	patient	ADJ
gs-3921	98	5	education	education	NOUN
gs-3921	98	6	and	and	CCONJ
gs-3921	98	7	support	support	NOUN
gs-3921	98	8	must	must	AUX
gs-3921	98	9	be	be	AUX
gs-3921	98	10	integral	integral	ADJ
gs-3921	98	11	components	component	NOUN
gs-3921	98	12	georgian	georgian	ADJ
gs-3921	98	13	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	98	14	მეცნიერები	მეცნიერები	NOUN
gs-3921	98	15	ტ.	ტ.	VERB
gs-3921	98	16	7	7	NUM
gs-3921	98	17	n	n	DET
gs-3921	98	18	3	3	NUM
gs-3921	98	19	,	,	PUNCT
gs-3921	98	20	2025	2025	NUM
gs-3921	98	21	224	224	NUM
gs-3921	98	22	of	of	ADP
gs-3921	98	23	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	98	24	initiatives	initiative	NOUN
gs-3921	98	25	to	to	PART
gs-3921	98	26	ensure	ensure	VERB
gs-3921	98	27	that	that	SCONJ
gs-3921	98	28	the	the	DET
gs-3921	98	29	knowledge	knowledge	NOUN
gs-3921	98	30	generated	generate	VERB
gs-3921	98	31	is	be	AUX
gs-3921	98	32	both	both	PRON
gs-3921	98	33	meaningful	meaningful	ADJ
gs-3921	98	34	and	and	CCONJ
gs-3921	98	35	actionable	actionable	ADJ
gs-3921	98	36	.	.	PUNCT
gs-3921	99	1	medication	medication	NOUN
gs-3921	99	2	-	-	PUNCT
gs-3921	99	3	induced	induce	VERB
gs-3921	99	4	adverse	adverse	ADJ
gs-3921	99	5	effects	effect	NOUN
gs-3921	99	6	remain	remain	VERB
gs-3921	99	7	among	among	ADP
gs-3921	99	8	the	the	DET
gs-3921	99	9	most	most	ADV
gs-3921	99	10	pressing	pressing	ADJ
gs-3921	99	11	challenges	challenge	NOUN
gs-3921	99	12	in	in	ADP
gs-3921	99	13	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	99	14	.	.	PUNCT
gs-3921	100	1	these	these	DET
gs-3921	100	2	events	event	NOUN
gs-3921	100	3	can	can	AUX
gs-3921	100	4	range	range	VERB
gs-3921	100	5	from	from	ADP
gs-3921	100	6	mild	mild	ADJ
gs-3921	100	7	,	,	PUNCT
gs-3921	100	8	transient	transient	ADJ
gs-3921	100	9	symptoms	symptom	NOUN
gs-3921	100	10	to	to	AUX
gs-3921	100	11	severe	severe	ADJ
gs-3921	100	12	,	,	PUNCT
gs-3921	100	13	lifethreatening	lifethreatene	VERB
gs-3921	100	14	syndromes	syndrome	NOUN
gs-3921	100	15	that	that	PRON
gs-3921	100	16	necessitate	necessitate	ADJ
gs-3921	100	17	intensive	intensive	ADJ
gs-3921	100	18	care	care	NOUN
gs-3921	100	19	and	and	CCONJ
gs-3921	100	20	long	long	ADJ
gs-3921	100	21	-	-	PUNCT
gs-3921	100	22	term	term	NOUN
gs-3921	100	23	sequelae	sequelae	NOUN
gs-3921	100	24	.	.	PUNCT
gs-3921	101	1	serious	serious	ADJ
gs-3921	101	2	adverse	adverse	ADJ
gs-3921	101	3	drug	drug	NOUN
gs-3921	101	4	reactions	reaction	NOUN
gs-3921	101	5	such	such	ADJ
gs-3921	101	6	as	as	ADP
gs-3921	101	7	stevens	stevens	PROPN
gs-3921	101	8	-	-	PUNCT
gs-3921	101	9	johnson	johnson	PROPN
gs-3921	101	10	syndrome	syndrome	PROPN
gs-3921	101	11	,	,	PUNCT
gs-3921	101	12	toxic	toxic	ADJ
gs-3921	101	13	epidermal	epidermal	ADJ
gs-3921	101	14	necrolysis	necrolysis	NOUN
gs-3921	101	15	,	,	PUNCT
gs-3921	101	16	drug	drug	NOUN
gs-3921	101	17	reaction	reaction	NOUN
gs-3921	101	18	with	with	ADP
gs-3921	101	19	eosinophilia	eosinophilia	PROPN
gs-3921	101	20	and	and	CCONJ
gs-3921	101	21	systemic	systemic	ADJ
gs-3921	101	22	symptoms	symptom	NOUN
gs-3921	101	23	(	(	PUNCT
gs-3921	101	24	dress	dress	NOUN
gs-3921	101	25	)	)	PUNCT
gs-3921	101	26	,	,	PUNCT
gs-3921	101	27	hepatotoxicity	hepatotoxicity	NOUN
gs-3921	101	28	,	,	PUNCT
gs-3921	101	29	nephrotoxicity	nephrotoxicity	NOUN
gs-3921	101	30	,	,	PUNCT
gs-3921	101	31	and	and	CCONJ
gs-3921	101	32	cardiotoxicity	cardiotoxicity	NOUN
gs-3921	101	33	are	be	AUX
gs-3921	101	34	often	often	ADV
gs-3921	101	35	unpredictable	unpredictable	ADJ
gs-3921	101	36	and	and	CCONJ
gs-3921	101	37	poorly	poorly	ADV
gs-3921	101	38	understood	understand	VERB
gs-3921	101	39	.	.	PUNCT
gs-3921	102	1	while	while	SCONJ
gs-3921	102	2	some	some	DET
gs-3921	102	3	adverse	adverse	ADJ
gs-3921	102	4	reactions	reaction	NOUN
gs-3921	102	5	are	be	AUX
gs-3921	102	6	dose	dose	NOUN
gs-3921	102	7	-	-	PUNCT
gs-3921	102	8	dependent	dependent	ADJ
gs-3921	102	9	and	and	CCONJ
gs-3921	102	10	may	may	AUX
gs-3921	102	11	be	be	AUX
gs-3921	102	12	mitigated	mitigate	VERB
gs-3921	102	13	through	through	ADP
gs-3921	102	14	careful	careful	ADJ
gs-3921	102	15	monitoring	monitoring	NOUN
gs-3921	102	16	,	,	PUNCT
gs-3921	102	17	others	other	NOUN
gs-3921	102	18	are	be	AUX
gs-3921	102	19	idiosyncratic	idiosyncratic	ADJ
gs-3921	102	20	and	and	CCONJ
gs-3921	102	21	arise	arise	VERB
gs-3921	102	22	from	from	ADP
gs-3921	102	23	immunological	immunological	ADJ
gs-3921	102	24	,	,	PUNCT
gs-3921	102	25	genetic	genetic	ADJ
gs-3921	102	26	,	,	PUNCT
gs-3921	102	27	or	or	CCONJ
gs-3921	102	28	metabolic	metabolic	NOUN
gs-3921	102	29	susceptibilities	susceptibility	NOUN
gs-3921	102	30	.	.	PUNCT
gs-3921	103	1	the	the	DET
gs-3921	103	2	unpredictable	unpredictable	ADJ
gs-3921	103	3	nature	nature	NOUN
gs-3921	103	4	of	of	ADP
gs-3921	103	5	such	such	ADJ
gs-3921	103	6	toxicities	toxicity	NOUN
gs-3921	103	7	necessitates	necessitate	VERB
gs-3921	103	8	a	a	DET
gs-3921	103	9	heightened	heightened	ADJ
gs-3921	103	10	focus	focus	NOUN
gs-3921	103	11	on	on	ADP
gs-3921	103	12	early	early	ADJ
gs-3921	103	13	detection	detection	NOUN
gs-3921	103	14	,	,	PUNCT
gs-3921	103	15	preemptive	preemptive	ADJ
gs-3921	103	16	risk	risk	NOUN
gs-3921	103	17	stratification	stratification	NOUN
gs-3921	103	18	,	,	PUNCT
gs-3921	103	19	and	and	CCONJ
gs-3921	103	20	robust	robust	ADJ
gs-3921	103	21	post	post	ADJ
gs-3921	103	22	-	-	ADJ
gs-3921	103	23	marketing	marketing	ADJ
gs-3921	103	24	surveillance	surveillance	NOUN
gs-3921	103	25	systems	system	NOUN
gs-3921	103	26	.	.	PUNCT
gs-3921	104	1	the	the	DET
gs-3921	104	2	field	field	NOUN
gs-3921	104	3	of	of	ADP
gs-3921	104	4	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	104	5	has	have	AUX
gs-3921	104	6	historically	historically	ADV
gs-3921	104	7	served	serve	VERB
gs-3921	104	8	as	as	ADP
gs-3921	104	9	the	the	DET
gs-3921	104	10	cornerstone	cornerstone	NOUN
gs-3921	104	11	of	of	ADP
gs-3921	104	12	drug	drug	NOUN
gs-3921	104	13	safety	safety	NOUN
gs-3921	104	14	monitoring	monitoring	NOUN
gs-3921	104	15	.	.	PUNCT
gs-3921	105	1	initially	initially	ADV
gs-3921	105	2	designed	design	VERB
gs-3921	105	3	as	as	ADP
gs-3921	105	4	a	a	DET
gs-3921	105	5	reactive	reactive	ADJ
gs-3921	105	6	mechanism	mechanism	NOUN
gs-3921	105	7	to	to	PART
gs-3921	105	8	identify	identify	VERB
gs-3921	105	9	and	and	CCONJ
gs-3921	105	10	mitigate	mitigate	VERB
gs-3921	105	11	postmarketing	postmarkete	VERB
gs-3921	105	12	adverse	adverse	ADJ
gs-3921	105	13	events	event	NOUN
gs-3921	105	14	,	,	PUNCT
gs-3921	105	15	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	105	16	now	now	ADV
gs-3921	105	17	encompasses	encompass	VERB
gs-3921	105	18	a	a	DET
gs-3921	105	19	broader	broad	ADJ
gs-3921	105	20	mandate	mandate	NOUN
gs-3921	105	21	that	that	PRON
gs-3921	105	22	includes	include	VERB
gs-3921	105	23	active	active	ADJ
gs-3921	105	24	surveillance	surveillance	NOUN
gs-3921	105	25	,	,	PUNCT
gs-3921	105	26	signal	signal	ADJ
gs-3921	105	27	detection	detection	NOUN
gs-3921	105	28	,	,	PUNCT
gs-3921	105	29	benefit	benefit	NOUN
gs-3921	105	30	-	-	PUNCT
gs-3921	105	31	risk	risk	NOUN
gs-3921	105	32	assessment	assessment	NOUN
gs-3921	105	33	,	,	PUNCT
gs-3921	105	34	and	and	CCONJ
gs-3921	105	35	regulatory	regulatory	ADJ
gs-3921	105	36	decision	decision	NOUN
gs-3921	105	37	-	-	PUNCT
gs-3921	105	38	making	making	NOUN
gs-3921	105	39	.	.	PUNCT
gs-3921	106	1	despite	despite	SCONJ
gs-3921	106	2	this	this	DET
gs-3921	106	3	expansion	expansion	NOUN
gs-3921	106	4	,	,	PUNCT
gs-3921	106	5	the	the	DET
gs-3921	106	6	traditional	traditional	ADJ
gs-3921	106	7	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	106	8	model	model	NOUN
gs-3921	106	9	remains	remains	AUX
gs-3921	106	10	challenged	challenge	VERB
gs-3921	106	11	by	by	ADP
gs-3921	106	12	fragmented	fragmented	ADJ
gs-3921	106	13	reporting	reporting	NOUN
gs-3921	106	14	systems	system	NOUN
gs-3921	106	15	,	,	PUNCT
gs-3921	106	16	underreporting	underreporting	NOUN
gs-3921	106	17	,	,	PUNCT
gs-3921	106	18	data	datum	NOUN
gs-3921	106	19	silos	silo	NOUN
gs-3921	106	20	,	,	PUNCT
gs-3921	106	21	and	and	CCONJ
gs-3921	106	22	variability	variability	NOUN
gs-3921	106	23	in	in	ADP
gs-3921	106	24	international	international	ADJ
gs-3921	106	25	regulatory	regulatory	ADJ
gs-3921	106	26	frameworks	framework	NOUN
gs-3921	106	27	.	.	PUNCT
gs-3921	107	1	efforts	effort	NOUN
gs-3921	107	2	to	to	PART
gs-3921	107	3	modernize	modernize	VERB
gs-3921	107	4	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	107	5	systems	system	NOUN
gs-3921	107	6	include	include	VERB
gs-3921	107	7	the	the	DET
gs-3921	107	8	development	development	NOUN
gs-3921	107	9	of	of	ADP
gs-3921	107	10	active	active	ADJ
gs-3921	107	11	surveillance	surveillance	NOUN
gs-3921	107	12	networks	network	NOUN
gs-3921	107	13	,	,	PUNCT
gs-3921	107	14	electronic	electronic	ADJ
gs-3921	107	15	health	health	NOUN
gs-3921	107	16	record	record	NOUN
gs-3921	107	17	(	(	PUNCT
gs-3921	107	18	ehr)linked	ehr)linke	VERB
gs-3921	107	19	databases	database	NOUN
gs-3921	107	20	,	,	PUNCT
gs-3921	107	21	patient	patient	NOUN
gs-3921	107	22	-	-	PUNCT
gs-3921	107	23	reported	report	VERB
gs-3921	107	24	outcome	outcome	NOUN
gs-3921	107	25	tools	tool	NOUN
gs-3921	107	26	,	,	PUNCT
gs-3921	107	27	and	and	CCONJ
gs-3921	107	28	machine	machine	NOUN
gs-3921	107	29	learning	learn	VERB
gs-3921	107	30	algorithms	algorithm	NOUN
gs-3921	107	31	capable	capable	ADJ
gs-3921	107	32	of	of	ADP
gs-3921	107	33	mining	mine	VERB
gs-3921	107	34	real	real	ADJ
gs-3921	107	35	-	-	PUNCT
gs-3921	107	36	world	world	NOUN
gs-3921	107	37	data	datum	NOUN
gs-3921	107	38	for	for	ADP
gs-3921	107	39	emerging	emerge	VERB
gs-3921	107	40	safety	safety	NOUN
gs-3921	107	41	signals	signal	NOUN
gs-3921	107	42	.	.	PUNCT
gs-3921	108	1	nevertheless	nevertheless	ADV
gs-3921	108	2	,	,	PUNCT
gs-3921	108	3	these	these	DET
gs-3921	108	4	tools	tool	NOUN
gs-3921	108	5	are	be	AUX
gs-3921	108	6	often	often	ADV
gs-3921	108	7	limited	limit	VERB
gs-3921	108	8	by	by	ADP
gs-3921	108	9	inconsistent	inconsistent	ADJ
gs-3921	108	10	data	datum	NOUN
gs-3921	108	11	quality	quality	NOUN
gs-3921	108	12	,	,	PUNCT
gs-3921	108	13	lack	lack	NOUN
gs-3921	108	14	of	of	ADP
gs-3921	108	15	interoperability	interoperability	NOUN
gs-3921	108	16	,	,	PUNCT
gs-3921	108	17	and	and	CCONJ
gs-3921	108	18	insufficient	insufficient	ADJ
gs-3921	108	19	integration	integration	NOUN
gs-3921	108	20	into	into	ADP
gs-3921	108	21	clinical	clinical	ADJ
gs-3921	108	22	workflows	workflow	NOUN
gs-3921	108	23	.	.	PUNCT
gs-3921	109	1	understanding	understand	VERB
gs-3921	109	2	the	the	DET
gs-3921	109	3	risk	risk	NOUN
gs-3921	109	4	factors	factor	NOUN
gs-3921	109	5	that	that	PRON
gs-3921	109	6	predispose	predispose	VERB
gs-3921	109	7	individuals	individual	NOUN
gs-3921	109	8	to	to	ADP
gs-3921	109	9	medication	medication	NOUN
gs-3921	109	10	-	-	PUNCT
gs-3921	109	11	related	relate	VERB
gs-3921	109	12	toxicities	toxicity	NOUN
gs-3921	109	13	is	be	AUX
gs-3921	109	14	crucial	crucial	ADJ
gs-3921	109	15	for	for	ADP
gs-3921	109	16	developing	develop	VERB
gs-3921	109	17	targeted	target	VERB
gs-3921	109	18	prevention	prevention	NOUN
gs-3921	109	19	and	and	CCONJ
gs-3921	109	20	management	management	NOUN
gs-3921	109	21	strategies	strategy	NOUN
gs-3921	109	22	.	.	PUNCT
gs-3921	110	1	agerelated	agerelate	VERB
gs-3921	110	2	physiological	physiological	ADJ
gs-3921	110	3	changes	change	NOUN
gs-3921	110	4	,	,	PUNCT
gs-3921	110	5	such	such	ADJ
gs-3921	110	6	as	as	ADP
gs-3921	110	7	reduced	reduced	ADJ
gs-3921	110	8	renal	renal	ADJ
gs-3921	110	9	and	and	CCONJ
gs-3921	110	10	hepatic	hepatic	ADJ
gs-3921	110	11	function	function	NOUN
gs-3921	110	12	,	,	PUNCT
gs-3921	110	13	altered	alter	VERB
gs-3921	110	14	drug	drug	NOUN
gs-3921	110	15	absorption	absorption	NOUN
gs-3921	110	16	and	and	CCONJ
gs-3921	110	17	distribution	distribution	NOUN
gs-3921	110	18	,	,	PUNCT
gs-3921	110	19	and	and	CCONJ
gs-3921	110	20	polypharmacy	polypharmacy	NOUN
gs-3921	110	21	,	,	PUNCT
gs-3921	110	22	render	render	VERB
gs-3921	110	23	elderly	elderly	ADJ
gs-3921	110	24	populations	population	NOUN
gs-3921	110	25	particularly	particularly	ADV
gs-3921	110	26	susceptible	susceptible	ADJ
gs-3921	110	27	to	to	ADP
gs-3921	110	28	adverse	adverse	ADJ
gs-3921	110	29	events	event	NOUN
gs-3921	110	30	.	.	PUNCT
gs-3921	111	1	pediatric	pediatric	ADJ
gs-3921	111	2	populations	population	NOUN
gs-3921	111	3	present	present	VERB
gs-3921	111	4	unique	unique	ADJ
gs-3921	111	5	challenges	challenge	NOUN
gs-3921	111	6	due	due	ADP
gs-3921	111	7	to	to	ADP
gs-3921	111	8	developmental	developmental	ADJ
gs-3921	111	9	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	111	10	and	and	CCONJ
gs-3921	111	11	the	the	DET
gs-3921	111	12	scarcity	scarcity	NOUN
gs-3921	111	13	of	of	ADP
gs-3921	111	14	age	age	NOUN
gs-3921	111	15	-	-	PUNCT
gs-3921	111	16	appropriate	appropriate	ADJ
gs-3921	111	17	formulations	formulation	NOUN
gs-3921	111	18	.	.	PUNCT
gs-3921	112	1	gender	gender	NOUN
gs-3921	112	2	differences	difference	NOUN
gs-3921	112	3	,	,	PUNCT
gs-3921	112	4	such	such	ADJ
gs-3921	112	5	as	as	ADP
gs-3921	112	6	hormonal	hormonal	ADJ
gs-3921	112	7	influences	influence	NOUN
gs-3921	112	8	on	on	ADP
gs-3921	112	9	drug	drug	NOUN
gs-3921	112	10	metabolism	metabolism	NOUN
gs-3921	112	11	and	and	CCONJ
gs-3921	112	12	immune	immune	ADJ
gs-3921	112	13	response	response	NOUN
gs-3921	112	14	,	,	PUNCT
gs-3921	112	15	can	can	AUX
gs-3921	112	16	also	also	ADV
gs-3921	112	17	affect	affect	VERB
gs-3921	112	18	susceptibility	susceptibility	NOUN
gs-3921	112	19	to	to	ADP
gs-3921	112	20	specific	specific	ADJ
gs-3921	112	21	toxicities	toxicity	NOUN
gs-3921	112	22	.	.	PUNCT
gs-3921	113	1	genetic	genetic	ADJ
gs-3921	113	2	ancestry	ancestry	NOUN
gs-3921	113	3	and	and	CCONJ
gs-3921	113	4	population	population	NOUN
gs-3921	113	5	-	-	PUNCT
gs-3921	113	6	specific	specific	ADJ
gs-3921	113	7	allele	allele	NOUN
gs-3921	113	8	frequencies	frequency	NOUN
gs-3921	113	9	influence	influence	VERB
gs-3921	113	10	the	the	DET
gs-3921	113	11	distribution	distribution	NOUN
gs-3921	113	12	of	of	ADP
gs-3921	113	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	113	14	variants	variant	NOUN
gs-3921	113	15	,	,	PUNCT
gs-3921	113	16	which	which	PRON
gs-3921	113	17	has	have	VERB
gs-3921	113	18	implications	implication	NOUN
gs-3921	113	19	for	for	ADP
gs-3921	113	20	drug	drug	NOUN
gs-3921	113	21	response	response	NOUN
gs-3921	113	22	and	and	CCONJ
gs-3921	113	23	safety	safety	NOUN
gs-3921	113	24	across	across	ADP
gs-3921	113	25	ethnic	ethnic	ADJ
gs-3921	113	26	groups	group	NOUN
gs-3921	113	27	.	.	PUNCT
gs-3921	114	1	additionally	additionally	ADV
gs-3921	114	2	,	,	PUNCT
gs-3921	114	3	comorbidities	comorbiditie	NOUN
gs-3921	114	4	such	such	ADJ
gs-3921	114	5	as	as	ADP
gs-3921	114	6	diabetes	diabete	NOUN
gs-3921	114	7	,	,	PUNCT
gs-3921	114	8	cardiovascular	cardiovascular	ADJ
gs-3921	114	9	disease	disease	NOUN
gs-3921	114	10	,	,	PUNCT
gs-3921	114	11	liver	liver	NOUN
gs-3921	114	12	dysfunction	dysfunction	NOUN
gs-3921	114	13	,	,	PUNCT
gs-3921	114	14	and	and	CCONJ
gs-3921	114	15	cancer	cancer	NOUN
gs-3921	114	16	can	can	AUX
gs-3921	114	17	modulate	modulate	VERB
gs-3921	114	18	drug	drug	NOUN
gs-3921	114	19	metabolism	metabolism	NOUN
gs-3921	114	20	and	and	CCONJ
gs-3921	114	21	increase	increase	VERB
gs-3921	114	22	vulnerability	vulnerability	NOUN
gs-3921	114	23	to	to	ADP
gs-3921	114	24	toxicity	toxicity	NOUN
gs-3921	114	25	.	.	PUNCT
gs-3921	115	1	these	these	DET
gs-3921	115	2	patient	patient	NOUN
gs-3921	115	3	-	-	PUNCT
gs-3921	115	4	related	relate	VERB
gs-3921	115	5	factors	factor	NOUN
gs-3921	115	6	must	must	AUX
gs-3921	115	7	be	be	AUX
gs-3921	115	8	considered	consider	VERB
gs-3921	115	9	alongside	alongside	ADP
gs-3921	115	10	drug	drug	NOUN
gs-3921	115	11	-	-	PUNCT
gs-3921	115	12	related	relate	VERB
gs-3921	115	13	characteristics	characteristic	NOUN
gs-3921	115	14	such	such	ADJ
gs-3921	115	15	as	as	ADP
gs-3921	115	16	narrow	narrow	ADJ
gs-3921	115	17	therapeutic	therapeutic	ADJ
gs-3921	115	18	index	index	NOUN
gs-3921	115	19	,	,	PUNCT
gs-3921	115	20	metabolic	metabolic	NOUN
gs-3921	115	21	pathway	pathway	NOUN
gs-3921	115	22	complexity	complexity	NOUN
gs-3921	115	23	,	,	PUNCT
gs-3921	115	24	potential	potential	NOUN
gs-3921	115	25	for	for	ADP
gs-3921	115	26	accumulation	accumulation	NOUN
gs-3921	115	27	,	,	PUNCT
gs-3921	115	28	and	and	CCONJ
gs-3921	115	29	known	know	VERB
gs-3921	115	30	toxic	toxic	ADJ
gs-3921	115	31	metabolite	metabolite	NOUN
gs-3921	115	32	profiles	profile	NOUN
gs-3921	115	33	.	.	PUNCT
gs-3921	116	1	georgian	georgian	ADJ
gs-3921	116	2	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	116	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	116	4	ტ.	ტ.	VERB
gs-3921	116	5	7	7	NUM
gs-3921	116	6	n	n	PRON
gs-3921	116	7	3	3	NUM
gs-3921	116	8	,	,	PUNCT
gs-3921	116	9	2025	2025	NUM
gs-3921	116	10	225	225	NUM
gs-3921	116	11	certain	certain	ADJ
gs-3921	116	12	pharmacological	pharmacological	ADJ
gs-3921	116	13	classes	class	NOUN
gs-3921	116	14	are	be	AUX
gs-3921	116	15	disproportionately	disproportionately	ADV
gs-3921	116	16	represented	represent	VERB
gs-3921	116	17	in	in	ADP
gs-3921	116	18	reports	report	NOUN
gs-3921	116	19	of	of	ADP
gs-3921	116	20	serious	serious	ADJ
gs-3921	116	21	adverse	adverse	ADJ
gs-3921	116	22	drug	drug	NOUN
gs-3921	116	23	reactions	reaction	NOUN
gs-3921	116	24	.	.	PUNCT
gs-3921	117	1	antineoplastic	antineoplastic	ADJ
gs-3921	117	2	agents	agent	NOUN
gs-3921	117	3	,	,	PUNCT
gs-3921	117	4	while	while	SCONJ
gs-3921	117	5	often	often	ADV
gs-3921	117	6	life	life	NOUN
gs-3921	117	7	-	-	PUNCT
gs-3921	117	8	saving	saving	NOUN
gs-3921	117	9	,	,	PUNCT
gs-3921	117	10	are	be	AUX
gs-3921	117	11	associated	associate	VERB
gs-3921	117	12	with	with	ADP
gs-3921	117	13	a	a	DET
gs-3921	117	14	wide	wide	ADJ
gs-3921	117	15	array	array	NOUN
gs-3921	117	16	of	of	ADP
gs-3921	117	17	toxicities	toxicity	NOUN
gs-3921	117	18	affecting	affect	VERB
gs-3921	117	19	nearly	nearly	ADV
gs-3921	117	20	every	every	PRON
gs-3921	117	21	organ	organ	NOUN
gs-3921	117	22	system	system	NOUN
gs-3921	117	23	.	.	PUNCT
gs-3921	118	1	immune	immune	ADJ
gs-3921	118	2	checkpoint	checkpoint	NOUN
gs-3921	118	3	inhibitors	inhibitor	NOUN
gs-3921	118	4	,	,	PUNCT
gs-3921	118	5	for	for	ADP
gs-3921	118	6	example	example	NOUN
gs-3921	118	7	,	,	PUNCT
gs-3921	118	8	have	have	AUX
gs-3921	118	9	revolutionized	revolutionize	VERB
gs-3921	118	10	oncology	oncology	NOUN
gs-3921	118	11	but	but	CCONJ
gs-3921	118	12	are	be	AUX
gs-3921	118	13	linked	link	VERB
gs-3921	118	14	to	to	ADP
gs-3921	118	15	immune	immune	NOUN
gs-3921	118	16	-	-	PUNCT
gs-3921	118	17	related	relate	VERB
gs-3921	118	18	adverse	adverse	ADJ
gs-3921	118	19	events	event	NOUN
gs-3921	118	20	that	that	PRON
gs-3921	118	21	can	can	AUX
gs-3921	118	22	mimic	mimic	VERB
gs-3921	118	23	autoimmune	autoimmune	ADJ
gs-3921	118	24	diseases	disease	NOUN
gs-3921	118	25	.	.	PUNCT
gs-3921	119	1	antimicrobial	antimicrobial	ADJ
gs-3921	119	2	agents	agent	NOUN
gs-3921	119	3	,	,	PUNCT
gs-3921	119	4	particularly	particularly	ADV
gs-3921	119	5	sulfonamides	sulfonamide	NOUN
gs-3921	119	6	,	,	PUNCT
gs-3921	119	7	beta	beta	NOUN
gs-3921	119	8	-	-	PUNCT
gs-3921	119	9	lactams	lactam	NOUN
gs-3921	119	10	,	,	PUNCT
gs-3921	119	11	and	and	CCONJ
gs-3921	119	12	antitubercular	antitubercular	ADJ
gs-3921	119	13	drugs	drug	NOUN
gs-3921	119	14	,	,	PUNCT
gs-3921	119	15	have	have	AUX
gs-3921	119	16	been	be	AUX
gs-3921	119	17	implicated	implicate	VERB
gs-3921	119	18	in	in	ADP
gs-3921	119	19	hypersensitivity	hypersensitivity	NOUN
gs-3921	119	20	reactions	reaction	NOUN
gs-3921	119	21	including	include	VERB
gs-3921	119	22	dress	dress	NOUN
gs-3921	119	23	and	and	CCONJ
gs-3921	119	24	anaphylaxis	anaphylaxis	ADJ
gs-3921	119	25	.	.	PUNCT
gs-3921	120	1	anticonvulsants	anticonvulsant	NOUN
gs-3921	120	2	such	such	ADJ
gs-3921	120	3	as	as	ADP
gs-3921	120	4	carbamazepine	carbamazepine	NOUN
gs-3921	120	5	and	and	CCONJ
gs-3921	120	6	phenytoin	phenytoin	NOUN
gs-3921	120	7	are	be	AUX
gs-3921	120	8	associated	associate	VERB
gs-3921	120	9	with	with	ADP
gs-3921	120	10	severe	severe	ADJ
gs-3921	120	11	dermatologic	dermatologic	ADJ
gs-3921	120	12	reactions	reaction	NOUN
gs-3921	120	13	in	in	ADP
gs-3921	120	14	genetically	genetically	ADV
gs-3921	120	15	susceptible	susceptible	ADJ
gs-3921	120	16	individuals	individual	NOUN
gs-3921	120	17	,	,	PUNCT
gs-3921	120	18	particularly	particularly	ADV
gs-3921	120	19	those	those	PRON
gs-3921	120	20	carrying	carry	VERB
gs-3921	120	21	hla	hla	NOUN
gs-3921	120	22	-	-	PUNCT
gs-3921	120	23	b15:02	b15:02	PROPN
gs-3921	120	24	or	or	CCONJ
gs-3921	120	25	hla	hla	PROPN
gs-3921	120	26	-	-	PUNCT
gs-3921	120	27	a31:01	a31:01	PROPN
gs-3921	120	28	alleles	allele	NOUN
gs-3921	120	29	.	.	PUNCT
gs-3921	121	1	psychotropic	psychotropic	ADJ
gs-3921	121	2	medications	medication	NOUN
gs-3921	121	3	,	,	PUNCT
gs-3921	121	4	including	include	VERB
gs-3921	121	5	selective	selective	ADJ
gs-3921	121	6	serotonin	serotonin	NOUN
gs-3921	121	7	reuptake	reuptake	NOUN
gs-3921	121	8	inhibitors	inhibitor	NOUN
gs-3921	121	9	(	(	PUNCT
gs-3921	121	10	ssris	ssris	NOUN
gs-3921	121	11	)	)	PUNCT
gs-3921	121	12	and	and	CCONJ
gs-3921	121	13	antipsychotics	antipsychotic	NOUN
gs-3921	121	14	,	,	PUNCT
gs-3921	121	15	carry	carry	VERB
gs-3921	121	16	risks	risk	NOUN
gs-3921	121	17	of	of	ADP
gs-3921	121	18	qt	qt	NOUN
gs-3921	121	19	prolongation	prolongation	NOUN
gs-3921	121	20	,	,	PUNCT
gs-3921	121	21	extrapyramidal	extrapyramidal	ADJ
gs-3921	121	22	symptoms	symptom	NOUN
gs-3921	121	23	,	,	PUNCT
gs-3921	121	24	and	and	CCONJ
gs-3921	121	25	metabolic	metabolic	NOUN
gs-3921	121	26	disturbances	disturbance	NOUN
gs-3921	121	27	.	.	PUNCT
gs-3921	122	1	biologic	biologic	NOUN
gs-3921	122	2	agents	agent	NOUN
gs-3921	122	3	and	and	CCONJ
gs-3921	122	4	monoclonal	monoclonal	NOUN
gs-3921	122	5	antibodies	antibodie	VERB
gs-3921	122	6	,	,	PUNCT
gs-3921	122	7	despite	despite	SCONJ
gs-3921	122	8	their	their	PRON
gs-3921	122	9	targeted	target	VERB
gs-3921	122	10	mechanisms	mechanism	NOUN
gs-3921	122	11	,	,	PUNCT
gs-3921	122	12	can	can	AUX
gs-3921	122	13	cause	cause	VERB
gs-3921	122	14	infusion	infusion	NOUN
gs-3921	122	15	reactions	reaction	NOUN
gs-3921	122	16	,	,	PUNCT
gs-3921	122	17	cytokine	cytokine	ADJ
gs-3921	122	18	release	release	NOUN
gs-3921	122	19	syndrome	syndrome	NOUN
gs-3921	122	20	,	,	PUNCT
gs-3921	122	21	and	and	CCONJ
gs-3921	122	22	immunogenicity	immunogenicity	NOUN
gs-3921	122	23	-	-	PUNCT
gs-3921	122	24	related	relate	VERB
gs-3921	122	25	complications	complication	NOUN
gs-3921	122	26	.	.	PUNCT
gs-3921	123	1	the	the	DET
gs-3921	123	2	diverse	diverse	ADJ
gs-3921	123	3	toxicity	toxicity	NOUN
gs-3921	123	4	profiles	profile	NOUN
gs-3921	123	5	of	of	ADP
gs-3921	123	6	these	these	DET
gs-3921	123	7	agents	agent	NOUN
gs-3921	123	8	necessitate	necessitate	VERB
gs-3921	123	9	a	a	DET
gs-3921	123	10	comprehensive	comprehensive	ADJ
gs-3921	123	11	understanding	understanding	NOUN
gs-3921	123	12	of	of	ADP
gs-3921	123	13	their	their	PRON
gs-3921	123	14	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	123	15	,	,	PUNCT
gs-3921	123	16	immunologic	immunologic	ADJ
gs-3921	123	17	potential	potential	NOUN
gs-3921	123	18	,	,	PUNCT
gs-3921	123	19	and	and	CCONJ
gs-3921	123	20	interindividual	interindividual	ADJ
gs-3921	123	21	variability	variability	NOUN
gs-3921	123	22	.	.	PUNCT
gs-3921	124	1	addressing	address	VERB
gs-3921	124	2	the	the	DET
gs-3921	124	3	challenges	challenge	NOUN
gs-3921	124	4	of	of	ADP
gs-3921	124	5	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	124	6	requires	require	VERB
gs-3921	124	7	the	the	DET
gs-3921	124	8	development	development	NOUN
gs-3921	124	9	and	and	CCONJ
gs-3921	124	10	implementation	implementation	NOUN
gs-3921	124	11	of	of	ADP
gs-3921	124	12	robust	robust	ADJ
gs-3921	124	13	strategic	strategic	ADJ
gs-3921	124	14	frameworks	framework	NOUN
gs-3921	124	15	that	that	PRON
gs-3921	124	16	integrate	integrate	VERB
gs-3921	124	17	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	124	18	data	datum	NOUN
gs-3921	124	19	,	,	PUNCT
gs-3921	124	20	clinical	clinical	ADJ
gs-3921	124	21	guidelines	guideline	NOUN
gs-3921	124	22	,	,	PUNCT
gs-3921	124	23	and	and	CCONJ
gs-3921	124	24	patient	patient	NOUN
gs-3921	124	25	-	-	PUNCT
gs-3921	124	26	reported	report	VERB
gs-3921	124	27	outcomes	outcome	NOUN
gs-3921	124	28	into	into	ADP
gs-3921	124	29	a	a	DET
gs-3921	124	30	unified	unified	ADJ
gs-3921	124	31	system	system	NOUN
gs-3921	124	32	of	of	ADP
gs-3921	124	33	care	care	NOUN
gs-3921	124	34	.	.	PUNCT
gs-3921	125	1	clinical	clinical	ADJ
gs-3921	125	2	decision	decision	NOUN
gs-3921	125	3	support	support	NOUN
gs-3921	125	4	systems	system	NOUN
gs-3921	125	5	(	(	PUNCT
gs-3921	125	6	cdss	cdss	NOUN
gs-3921	125	7	)	)	PUNCT
gs-3921	125	8	embedded	embed	VERB
gs-3921	125	9	within	within	ADP
gs-3921	125	10	ehrs	ehrs	PROPN
gs-3921	125	11	have	have	VERB
gs-3921	125	12	the	the	DET
gs-3921	125	13	potential	potential	NOUN
gs-3921	125	14	to	to	PART
gs-3921	125	15	alert	alert	VERB
gs-3921	125	16	prescribers	prescriber	NOUN
gs-3921	125	17	to	to	ADP
gs-3921	125	18	potential	potential	ADJ
gs-3921	125	19	drug	drug	NOUN
gs-3921	125	20	-	-	PUNCT
gs-3921	125	21	gene	gene	NOUN
gs-3921	125	22	interactions	interaction	NOUN
gs-3921	125	23	,	,	PUNCT
gs-3921	125	24	dosing	dose	VERB
gs-3921	125	25	recommendations	recommendation	NOUN
gs-3921	125	26	based	base	VERB
gs-3921	125	27	on	on	ADP
gs-3921	125	28	genotype	genotype	NOUN
gs-3921	125	29	,	,	PUNCT
gs-3921	125	30	and	and	CCONJ
gs-3921	125	31	real	real	ADJ
gs-3921	125	32	-	-	PUNCT
gs-3921	125	33	time	time	NOUN
gs-3921	125	34	monitoring	monitoring	NOUN
gs-3921	125	35	of	of	ADP
gs-3921	125	36	drug	drug	NOUN
gs-3921	125	37	safety	safety	NOUN
gs-3921	125	38	parameters	parameter	NOUN
gs-3921	125	39	.	.	PUNCT
gs-3921	126	1	such	such	ADJ
gs-3921	126	2	tools	tool	NOUN
gs-3921	126	3	,	,	PUNCT
gs-3921	126	4	however	however	ADV
gs-3921	126	5	,	,	PUNCT
gs-3921	126	6	must	must	AUX
gs-3921	126	7	be	be	AUX
gs-3921	126	8	evidence	evidence	NOUN
gs-3921	126	9	-	-	PUNCT
gs-3921	126	10	based	base	VERB
gs-3921	126	11	,	,	PUNCT
gs-3921	126	12	regularly	regularly	ADV
gs-3921	126	13	updated	update	VERB
gs-3921	126	14	,	,	PUNCT
gs-3921	126	15	and	and	CCONJ
gs-3921	126	16	contextually	contextually	ADV
gs-3921	126	17	relevant	relevant	ADJ
gs-3921	126	18	to	to	PART
gs-3921	126	19	ensure	ensure	VERB
gs-3921	126	20	clinical	clinical	ADJ
gs-3921	126	21	utility	utility	NOUN
gs-3921	126	22	.	.	PUNCT
gs-3921	127	1	moreover	moreover	ADV
gs-3921	127	2	,	,	PUNCT
gs-3921	127	3	the	the	DET
gs-3921	127	4	success	success	NOUN
gs-3921	127	5	of	of	ADP
gs-3921	127	6	these	these	DET
gs-3921	127	7	systems	system	NOUN
gs-3921	127	8	depends	depend	VERB
gs-3921	127	9	on	on	ADP
gs-3921	127	10	the	the	DET
gs-3921	127	11	active	active	ADJ
gs-3921	127	12	engagement	engagement	NOUN
gs-3921	127	13	of	of	ADP
gs-3921	127	14	multidisciplinary	multidisciplinary	ADJ
gs-3921	127	15	teams	team	NOUN
gs-3921	127	16	,	,	PUNCT
gs-3921	127	17	including	include	VERB
gs-3921	127	18	pharmacists	pharmacist	NOUN
gs-3921	127	19	,	,	PUNCT
gs-3921	127	20	genetic	genetic	ADJ
gs-3921	127	21	counselors	counselor	NOUN
gs-3921	127	22	,	,	PUNCT
gs-3921	127	23	clinical	clinical	ADJ
gs-3921	127	24	pharmacologists	pharmacologist	NOUN
gs-3921	127	25	,	,	PUNCT
gs-3921	127	26	and	and	CCONJ
gs-3921	127	27	information	information	NOUN
gs-3921	127	28	technology	technology	NOUN
gs-3921	127	29	specialists	specialist	NOUN
gs-3921	127	30	.	.	PUNCT
gs-3921	128	1	education	education	NOUN
gs-3921	128	2	and	and	CCONJ
gs-3921	128	3	capacity	capacity	NOUN
gs-3921	128	4	building	building	NOUN
gs-3921	128	5	represent	represent	VERB
gs-3921	128	6	foundational	foundational	ADJ
gs-3921	128	7	pillars	pillar	NOUN
gs-3921	128	8	for	for	ADP
gs-3921	128	9	advancing	advance	VERB
gs-3921	128	10	the	the	DET
gs-3921	128	11	integration	integration	NOUN
gs-3921	128	12	of	of	ADP
gs-3921	128	13	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	128	14	and	and	CCONJ
gs-3921	128	15	personalized	personalized	ADJ
gs-3921	128	16	medicine	medicine	NOUN
gs-3921	128	17	into	into	ADP
gs-3921	128	18	routine	routine	ADJ
gs-3921	128	19	care	care	NOUN
gs-3921	128	20	.	.	PUNCT
gs-3921	129	1	medical	medical	ADJ
gs-3921	129	2	and	and	CCONJ
gs-3921	129	3	pharmacy	pharmacy	NOUN
gs-3921	129	4	curricula	curricula	NOUN
gs-3921	129	5	must	must	AUX
gs-3921	129	6	be	be	AUX
gs-3921	129	7	updated	update	VERB
gs-3921	129	8	to	to	PART
gs-3921	129	9	reflect	reflect	VERB
gs-3921	129	10	current	current	ADJ
gs-3921	129	11	knowledge	knowledge	NOUN
gs-3921	129	12	in	in	ADP
gs-3921	129	13	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	129	14	,	,	PUNCT
gs-3921	129	15	data	datum	NOUN
gs-3921	129	16	interpretation	interpretation	NOUN
gs-3921	129	17	,	,	PUNCT
gs-3921	129	18	ethical	ethical	ADJ
gs-3921	129	19	considerations	consideration	NOUN
gs-3921	129	20	,	,	PUNCT
gs-3921	129	21	and	and	CCONJ
gs-3921	129	22	communication	communication	NOUN
gs-3921	129	23	of	of	ADP
gs-3921	129	24	genetic	genetic	ADJ
gs-3921	129	25	risk	risk	NOUN
gs-3921	129	26	.	.	PUNCT
gs-3921	130	1	continuing	continue	VERB
gs-3921	130	2	professional	professional	ADJ
gs-3921	130	3	development	development	NOUN
gs-3921	130	4	programs	program	NOUN
gs-3921	130	5	should	should	AUX
gs-3921	130	6	be	be	AUX
gs-3921	130	7	designed	design	VERB
gs-3921	130	8	to	to	PART
gs-3921	130	9	equip	equip	VERB
gs-3921	130	10	practicing	practice	VERB
gs-3921	130	11	clinicians	clinician	NOUN
gs-3921	130	12	with	with	ADP
gs-3921	130	13	the	the	DET
gs-3921	130	14	skills	skill	NOUN
gs-3921	130	15	necessary	necessary	ADJ
gs-3921	130	16	to	to	PART
gs-3921	130	17	apply	apply	VERB
gs-3921	130	18	genetic	genetic	ADJ
gs-3921	130	19	information	information	NOUN
gs-3921	130	20	in	in	ADP
gs-3921	130	21	therapeutic	therapeutic	ADJ
gs-3921	130	22	decision	decision	NOUN
gs-3921	130	23	-	-	PUNCT
gs-3921	130	24	making	making	NOUN
gs-3921	130	25	.	.	PUNCT
gs-3921	131	1	patient	patient	ADJ
gs-3921	131	2	education	education	NOUN
gs-3921	131	3	initiatives	initiative	NOUN
gs-3921	131	4	must	must	AUX
gs-3921	131	5	also	also	ADV
gs-3921	131	6	be	be	AUX
gs-3921	131	7	prioritized	prioritize	VERB
gs-3921	131	8	to	to	PART
gs-3921	131	9	foster	foster	VERB
gs-3921	131	10	understanding	understanding	NOUN
gs-3921	131	11	,	,	PUNCT
gs-3921	131	12	dispel	dispel	NOUN
gs-3921	131	13	misconceptions	misconception	NOUN
gs-3921	131	14	,	,	PUNCT
gs-3921	131	15	and	and	CCONJ
gs-3921	131	16	encourage	encourage	VERB
gs-3921	131	17	participation	participation	NOUN
gs-3921	131	18	in	in	ADP
gs-3921	131	19	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	131	20	research	research	NOUN
gs-3921	131	21	and	and	CCONJ
gs-3921	131	22	testing	testing	NOUN
gs-3921	131	23	programs	program	NOUN
gs-3921	131	24	.	.	PUNCT
gs-3921	132	1	from	from	ADP
gs-3921	132	2	a	a	DET
gs-3921	132	3	policy	policy	NOUN
gs-3921	132	4	perspective	perspective	NOUN
gs-3921	132	5	,	,	PUNCT
gs-3921	132	6	the	the	DET
gs-3921	132	7	regulatory	regulatory	ADJ
gs-3921	132	8	landscape	landscape	NOUN
gs-3921	132	9	must	must	AUX
gs-3921	132	10	evolve	evolve	VERB
gs-3921	132	11	to	to	PART
gs-3921	132	12	support	support	VERB
gs-3921	132	13	the	the	DET
gs-3921	132	14	ethical	ethical	ADJ
gs-3921	132	15	and	and	CCONJ
gs-3921	132	16	practical	practical	ADJ
gs-3921	132	17	implementation	implementation	NOUN
gs-3921	132	18	of	of	ADP
gs-3921	132	19	precision	precision	NOUN
gs-3921	132	20	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	132	21	.	.	PUNCT
gs-3921	133	1	regulatory	regulatory	ADJ
gs-3921	133	2	agencies	agency	NOUN
gs-3921	133	3	should	should	AUX
gs-3921	133	4	establish	establish	VERB
gs-3921	133	5	clear	clear	ADJ
gs-3921	133	6	guidelines	guideline	NOUN
gs-3921	133	7	for	for	ADP
gs-3921	133	8	the	the	DET
gs-3921	133	9	validation	validation	NOUN
gs-3921	133	10	,	,	PUNCT
gs-3921	133	11	approval	approval	NOUN
gs-3921	133	12	,	,	PUNCT
gs-3921	133	13	and	and	CCONJ
gs-3921	133	14	reimbursement	reimbursement	NOUN
gs-3921	133	15	of	of	ADP
gs-3921	133	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	133	17	tests	test	NOUN
gs-3921	133	18	.	.	PUNCT
gs-3921	134	1	public	public	ADJ
gs-3921	134	2	health	health	NOUN
gs-3921	134	3	policies	policy	NOUN
gs-3921	134	4	should	should	AUX
gs-3921	134	5	incentivize	incentivize	VERB
gs-3921	134	6	the	the	DET
gs-3921	134	7	incorporation	incorporation	NOUN
gs-3921	134	8	of	of	ADP
gs-3921	134	9	genomic	genomic	ADJ
gs-3921	134	10	data	datum	NOUN
gs-3921	134	11	into	into	ADP
gs-3921	134	12	drug	drug	NOUN
gs-3921	134	13	development	development	NOUN
gs-3921	134	14	and	and	CCONJ
gs-3921	134	15	surveillance	surveillance	NOUN
gs-3921	134	16	processes	process	NOUN
gs-3921	134	17	.	.	PUNCT
gs-3921	135	1	international	international	ADJ
gs-3921	135	2	harmonization	harmonization	NOUN
gs-3921	135	3	of	of	ADP
gs-3921	135	4	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	135	5	nomenclature	nomenclature	NOUN
gs-3921	135	6	,	,	PUNCT
gs-3921	135	7	reporting	reporting	NOUN
gs-3921	135	8	standards	standard	NOUN
gs-3921	135	9	,	,	PUNCT
gs-3921	135	10	and	and	CCONJ
gs-3921	135	11	data	data	NOUN
gs-3921	135	12	-	-	PUNCT
gs-3921	135	13	sharing	share	VERB
gs-3921	135	14	georgian	georgian	ADJ
gs-3921	135	15	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	135	16	მეცნიერები	მეცნიერები	NOUN
gs-3921	135	17	ტ.	ტ.	VERB
gs-3921	135	18	7	7	NUM
gs-3921	135	19	n	n	PRON
gs-3921	135	20	3	3	NUM
gs-3921	135	21	,	,	PUNCT
gs-3921	135	22	2025	2025	NUM
gs-3921	135	23	226	226	NUM
gs-3921	135	24	frameworks	framework	NOUN
gs-3921	135	25	can	can	AUX
gs-3921	135	26	facilitate	facilitate	VERB
gs-3921	135	27	cross	cross	ADJ
gs-3921	135	28	-	-	ADJ
gs-3921	135	29	border	border	ADJ
gs-3921	135	30	research	research	NOUN
gs-3921	135	31	and	and	CCONJ
gs-3921	135	32	collaborative	collaborative	ADJ
gs-3921	135	33	innovation	innovation	NOUN
gs-3921	135	34	.	.	PUNCT
gs-3921	136	1	furthermore	furthermore	ADV
gs-3921	136	2	,	,	PUNCT
gs-3921	136	3	equitable	equitable	ADJ
gs-3921	136	4	access	access	NOUN
gs-3921	136	5	to	to	ADP
gs-3921	136	6	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	136	7	services	service	NOUN
gs-3921	136	8	must	must	AUX
gs-3921	136	9	be	be	AUX
gs-3921	136	10	ensured	ensure	VERB
gs-3921	136	11	to	to	PART
gs-3921	136	12	prevent	prevent	VERB
gs-3921	136	13	the	the	DET
gs-3921	136	14	exacerbation	exacerbation	NOUN
gs-3921	136	15	of	of	ADP
gs-3921	136	16	existing	exist	VERB
gs-3921	136	17	health	health	NOUN
gs-3921	136	18	disparities	disparity	NOUN
gs-3921	136	19	.	.	PUNCT
gs-3921	137	1	the	the	DET
gs-3921	137	2	future	future	NOUN
gs-3921	137	3	of	of	ADP
gs-3921	137	4	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	137	5	lies	lie	VERB
gs-3921	137	6	in	in	ADP
gs-3921	137	7	its	its	PRON
gs-3921	137	8	ability	ability	NOUN
gs-3921	137	9	to	to	PART
gs-3921	137	10	harmonize	harmonize	VERB
gs-3921	137	11	technological	technological	ADJ
gs-3921	137	12	innovation	innovation	NOUN
gs-3921	137	13	with	with	ADP
gs-3921	137	14	human	human	NOUN
gs-3921	137	15	-	-	PUNCT
gs-3921	137	16	centered	center	VERB
gs-3921	137	17	care	care	NOUN
gs-3921	137	18	.	.	PUNCT
gs-3921	138	1	as	as	SCONJ
gs-3921	138	2	healthcare	healthcare	NOUN
gs-3921	138	3	systems	system	NOUN
gs-3921	138	4	transition	transition	NOUN
gs-3921	138	5	toward	toward	ADP
gs-3921	138	6	value	value	NOUN
gs-3921	138	7	-	-	PUNCT
gs-3921	138	8	based	base	VERB
gs-3921	138	9	models	model	NOUN
gs-3921	138	10	that	that	PRON
gs-3921	138	11	prioritize	prioritize	VERB
gs-3921	138	12	outcomes	outcome	NOUN
gs-3921	138	13	and	and	CCONJ
gs-3921	138	14	patient	patient	ADJ
gs-3921	138	15	satisfaction	satisfaction	NOUN
gs-3921	138	16	,	,	PUNCT
gs-3921	138	17	the	the	DET
gs-3921	138	18	integration	integration	NOUN
gs-3921	138	19	of	of	ADP
gs-3921	138	20	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	138	21	insights	insight	NOUN
gs-3921	138	22	,	,	PUNCT
gs-3921	138	23	patient	patient	ADJ
gs-3921	138	24	narratives	narrative	NOUN
gs-3921	138	25	,	,	PUNCT
gs-3921	138	26	and	and	CCONJ
gs-3921	138	27	data	datum	NOUN
gs-3921	138	28	-	-	PUNCT
gs-3921	138	29	driven	drive	VERB
gs-3921	138	30	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	138	31	will	will	AUX
gs-3921	138	32	be	be	AUX
gs-3921	138	33	indispensable	indispensable	ADJ
gs-3921	138	34	.	.	PUNCT
gs-3921	139	1	this	this	DET
gs-3921	139	2	convergence	convergence	NOUN
gs-3921	139	3	offers	offer	VERB
gs-3921	139	4	a	a	DET
gs-3921	139	5	pathway	pathway	NOUN
gs-3921	139	6	to	to	PART
gs-3921	139	7	not	not	PART
gs-3921	139	8	only	only	ADV
gs-3921	139	9	mitigate	mitigate	VERB
gs-3921	139	10	the	the	DET
gs-3921	139	11	burden	burden	NOUN
gs-3921	139	12	of	of	ADP
gs-3921	139	13	medication	medication	NOUN
gs-3921	139	14	-	-	PUNCT
gs-3921	139	15	induced	induce	VERB
gs-3921	139	16	harm	harm	NOUN
gs-3921	139	17	but	but	CCONJ
gs-3921	139	18	also	also	ADV
gs-3921	139	19	to	to	PART
gs-3921	139	20	reimagine	reimagine	VERB
gs-3921	139	21	the	the	DET
gs-3921	139	22	therapeutic	therapeutic	ADJ
gs-3921	139	23	relationship	relationship	NOUN
gs-3921	139	24	as	as	ADP
gs-3921	139	25	a	a	DET
gs-3921	139	26	dynamic	dynamic	ADJ
gs-3921	139	27	,	,	PUNCT
gs-3921	139	28	personalized	personalized	ADJ
gs-3921	139	29	,	,	PUNCT
gs-3921	139	30	and	and	CCONJ
gs-3921	139	31	participatory	participatory	ADJ
gs-3921	139	32	endeavor	endeavor	NOUN
gs-3921	139	33	.	.	PUNCT
gs-3921	140	1	by	by	ADP
gs-3921	140	2	fostering	foster	VERB
gs-3921	140	3	an	an	DET
gs-3921	140	4	ecosystem	ecosystem	NOUN
gs-3921	140	5	that	that	PRON
gs-3921	140	6	embraces	embrace	VERB
gs-3921	140	7	scientific	scientific	ADJ
gs-3921	140	8	rigor	rigor	NOUN
gs-3921	140	9	,	,	PUNCT
gs-3921	140	10	clinical	clinical	ADJ
gs-3921	140	11	empathy	empathy	NOUN
gs-3921	140	12	,	,	PUNCT
gs-3921	140	13	and	and	CCONJ
gs-3921	140	14	ethical	ethical	ADJ
gs-3921	140	15	responsibility	responsibility	NOUN
gs-3921	140	16	,	,	PUNCT
gs-3921	140	17	the	the	DET
gs-3921	140	18	discipline	discipline	NOUN
gs-3921	140	19	of	of	ADP
gs-3921	140	20	pharmacotherapeutics	pharmacotherapeutic	NOUN
gs-3921	140	21	can	can	AUX
gs-3921	140	22	rise	rise	VERB
gs-3921	140	23	to	to	PART
gs-3921	140	24	meet	meet	VERB
gs-3921	140	25	the	the	DET
gs-3921	140	26	evolving	evolve	VERB
gs-3921	140	27	challenges	challenge	NOUN
gs-3921	140	28	of	of	ADP
gs-3921	140	29	modern	modern	ADJ
gs-3921	140	30	medicine	medicine	NOUN
gs-3921	140	31	.	.	PUNCT
gs-3921	141	1	goal	goal	NOUN
gs-3921	141	2	the	the	DET
gs-3921	141	3	overarching	overarching	ADJ
gs-3921	141	4	goal	goal	NOUN
gs-3921	141	5	of	of	ADP
gs-3921	141	6	this	this	DET
gs-3921	141	7	comprehensive	comprehensive	ADJ
gs-3921	141	8	study	study	NOUN
gs-3921	141	9	is	be	AUX
gs-3921	141	10	to	to	PART
gs-3921	141	11	elucidate	elucidate	VERB
gs-3921	141	12	and	and	CCONJ
gs-3921	141	13	synthesize	synthesize	VERB
gs-3921	141	14	current	current	ADJ
gs-3921	141	15	scientific	scientific	ADJ
gs-3921	141	16	knowledge	knowledge	NOUN
gs-3921	141	17	and	and	CCONJ
gs-3921	141	18	clinical	clinical	ADJ
gs-3921	141	19	practices	practice	NOUN
gs-3921	141	20	related	relate	VERB
gs-3921	141	21	to	to	ADP
gs-3921	141	22	the	the	DET
gs-3921	141	23	integration	integration	NOUN
gs-3921	141	24	of	of	ADP
gs-3921	141	25	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	141	26	insights	insight	NOUN
gs-3921	141	27	and	and	CCONJ
gs-3921	141	28	patient	patient	NOUN
gs-3921	141	29	-	-	PUNCT
gs-3921	141	30	centered	center	VERB
gs-3921	141	31	care	care	NOUN
gs-3921	141	32	approaches	approach	NOUN
gs-3921	141	33	in	in	ADP
gs-3921	141	34	addressing	address	VERB
gs-3921	141	35	medicationinduced	medicationinduce	VERB
gs-3921	141	36	adverse	adverse	ADJ
gs-3921	141	37	effects	effect	NOUN
gs-3921	141	38	and	and	CCONJ
gs-3921	141	39	toxicities	toxicity	NOUN
gs-3921	141	40	.	.	PUNCT
gs-3921	142	1	this	this	DET
gs-3921	142	2	work	work	NOUN
gs-3921	142	3	aims	aim	VERB
gs-3921	142	4	to	to	PART
gs-3921	142	5	critically	critically	ADV
gs-3921	142	6	analyze	analyze	VERB
gs-3921	142	7	the	the	DET
gs-3921	142	8	challenges	challenge	NOUN
gs-3921	142	9	faced	face	VERB
gs-3921	142	10	by	by	ADP
gs-3921	142	11	contemporary	contemporary	ADJ
gs-3921	142	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	142	13	systems	system	NOUN
gs-3921	142	14	in	in	ADP
gs-3921	142	15	effectively	effectively	ADV
gs-3921	142	16	detecting	detect	VERB
gs-3921	142	17	,	,	PUNCT
gs-3921	142	18	monitoring	monitoring	NOUN
gs-3921	142	19	,	,	PUNCT
gs-3921	142	20	and	and	CCONJ
gs-3921	142	21	managing	manage	VERB
gs-3921	142	22	adverse	adverse	ADJ
gs-3921	142	23	drug	drug	NOUN
gs-3921	142	24	reactions	reaction	NOUN
gs-3921	142	25	,	,	PUNCT
gs-3921	142	26	while	while	SCONJ
gs-3921	142	27	identifying	identify	VERB
gs-3921	142	28	the	the	DET
gs-3921	142	29	key	key	ADJ
gs-3921	142	30	pharmacological	pharmacological	ADJ
gs-3921	142	31	agents	agent	NOUN
gs-3921	142	32	most	most	ADV
gs-3921	142	33	frequently	frequently	ADV
gs-3921	142	34	implicated	implicate	VERB
gs-3921	142	35	in	in	ADP
gs-3921	142	36	such	such	ADJ
gs-3921	142	37	events	event	NOUN
gs-3921	142	38	.	.	PUNCT
gs-3921	143	1	by	by	ADP
gs-3921	143	2	investigating	investigate	VERB
gs-3921	143	3	the	the	DET
gs-3921	143	4	underlying	underlie	VERB
gs-3921	143	5	determinants	determinant	NOUN
gs-3921	143	6	of	of	ADP
gs-3921	143	7	risk	risk	NOUN
gs-3921	143	8	—	—	PUNCT
gs-3921	143	9	encompassing	encompass	VERB
gs-3921	143	10	genetic	genetic	ADJ
gs-3921	143	11	,	,	PUNCT
gs-3921	143	12	environmental	environmental	ADJ
gs-3921	143	13	,	,	PUNCT
gs-3921	143	14	demographic	demographic	ADJ
gs-3921	143	15	,	,	PUNCT
gs-3921	143	16	and	and	CCONJ
gs-3921	143	17	clinical	clinical	ADJ
gs-3921	143	18	factors	factor	NOUN
gs-3921	143	19	—	—	PUNCT
gs-3921	143	20	the	the	DET
gs-3921	143	21	study	study	NOUN
gs-3921	143	22	seeks	seek	VERB
gs-3921	143	23	to	to	PART
gs-3921	143	24	deepen	deepen	VERB
gs-3921	143	25	the	the	DET
gs-3921	143	26	understanding	understanding	NOUN
gs-3921	143	27	of	of	ADP
gs-3921	143	28	interindividual	interindividual	ADJ
gs-3921	143	29	variability	variability	NOUN
gs-3921	143	30	in	in	ADP
gs-3921	143	31	drug	drug	NOUN
gs-3921	143	32	response	response	NOUN
gs-3921	143	33	and	and	CCONJ
gs-3921	143	34	susceptibility	susceptibility	NOUN
gs-3921	143	35	to	to	ADP
gs-3921	143	36	toxicity	toxicity	NOUN
gs-3921	143	37	.	.	PUNCT
gs-3921	144	1	a	a	DET
gs-3921	144	2	fundamental	fundamental	ADJ
gs-3921	144	3	objective	objective	NOUN
gs-3921	144	4	is	be	AUX
gs-3921	144	5	to	to	PART
gs-3921	144	6	evaluate	evaluate	VERB
gs-3921	144	7	strategic	strategic	ADJ
gs-3921	144	8	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	144	9	management	management	NOUN
gs-3921	144	10	approaches	approach	NOUN
gs-3921	144	11	that	that	PRON
gs-3921	144	12	incorporate	incorporate	VERB
gs-3921	144	13	genetic	genetic	ADJ
gs-3921	144	14	testing	testing	NOUN
gs-3921	144	15	,	,	PUNCT
gs-3921	144	16	clinical	clinical	ADJ
gs-3921	144	17	decision	decision	NOUN
gs-3921	144	18	support	support	NOUN
gs-3921	144	19	,	,	PUNCT
gs-3921	144	20	and	and	CCONJ
gs-3921	144	21	personalized	personalize	VERB
gs-3921	144	22	patient	patient	ADJ
gs-3921	144	23	engagement	engagement	NOUN
gs-3921	144	24	to	to	PART
gs-3921	144	25	optimize	optimize	VERB
gs-3921	144	26	drug	drug	NOUN
gs-3921	144	27	safety	safety	NOUN
gs-3921	144	28	and	and	CCONJ
gs-3921	144	29	efficacy	efficacy	NOUN
gs-3921	144	30	.	.	PUNCT
gs-3921	145	1	this	this	PRON
gs-3921	145	2	includes	include	VERB
gs-3921	145	3	examining	examine	VERB
gs-3921	145	4	current	current	ADJ
gs-3921	145	5	methodologies	methodology	NOUN
gs-3921	145	6	,	,	PUNCT
gs-3921	145	7	emerging	emerge	VERB
gs-3921	145	8	technologies	technology	NOUN
gs-3921	145	9	,	,	PUNCT
gs-3921	145	10	and	and	CCONJ
gs-3921	145	11	evidence	evidence	NOUN
gs-3921	145	12	-	-	PUNCT
gs-3921	145	13	based	base	VERB
gs-3921	145	14	guidelines	guideline	NOUN
gs-3921	145	15	that	that	PRON
gs-3921	145	16	facilitate	facilitate	VERB
gs-3921	145	17	tailored	tailor	VERB
gs-3921	145	18	treatment	treatment	NOUN
gs-3921	145	19	regimens	regimen	NOUN
gs-3921	145	20	and	and	CCONJ
gs-3921	145	21	proactive	proactive	ADJ
gs-3921	145	22	risk	risk	NOUN
gs-3921	145	23	mitigation	mitigation	NOUN
gs-3921	145	24	.	.	PUNCT
gs-3921	146	1	furthermore	furthermore	ADV
gs-3921	146	2	,	,	PUNCT
gs-3921	146	3	the	the	DET
gs-3921	146	4	study	study	NOUN
gs-3921	146	5	aspires	aspire	VERB
gs-3921	146	6	to	to	PART
gs-3921	146	7	highlight	highlight	VERB
gs-3921	146	8	existing	exist	VERB
gs-3921	146	9	gaps	gap	NOUN
gs-3921	146	10	and	and	CCONJ
gs-3921	146	11	barriers	barrier	NOUN
gs-3921	146	12	in	in	ADP
gs-3921	146	13	the	the	DET
gs-3921	146	14	translation	translation	NOUN
gs-3921	146	15	of	of	ADP
gs-3921	146	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	146	17	research	research	NOUN
gs-3921	146	18	into	into	ADP
gs-3921	146	19	routine	routine	ADJ
gs-3921	146	20	clinical	clinical	ADJ
gs-3921	146	21	practice	practice	NOUN
gs-3921	146	22	,	,	PUNCT
gs-3921	146	23	proposing	propose	VERB
gs-3921	146	24	practical	practical	ADJ
gs-3921	146	25	solutions	solution	NOUN
gs-3921	146	26	to	to	PART
gs-3921	146	27	enhance	enhance	VERB
gs-3921	146	28	accessibility	accessibility	NOUN
gs-3921	146	29	,	,	PUNCT
gs-3921	146	30	clinician	clinician	ADJ
gs-3921	146	31	education	education	NOUN
gs-3921	146	32	,	,	PUNCT
gs-3921	146	33	and	and	CCONJ
gs-3921	146	34	healthcare	healthcare	NOUN
gs-3921	146	35	system	system	NOUN
gs-3921	146	36	integration	integration	NOUN
gs-3921	146	37	.	.	PUNCT
gs-3921	147	1	another	another	DET
gs-3921	147	2	critical	critical	ADJ
gs-3921	147	3	goal	goal	NOUN
gs-3921	147	4	is	be	AUX
gs-3921	147	5	to	to	PART
gs-3921	147	6	explore	explore	VERB
gs-3921	147	7	the	the	DET
gs-3921	147	8	ethical	ethical	ADJ
gs-3921	147	9	,	,	PUNCT
gs-3921	147	10	legal	legal	ADJ
gs-3921	147	11	,	,	PUNCT
gs-3921	147	12	and	and	CCONJ
gs-3921	147	13	social	social	ADJ
gs-3921	147	14	considerations	consideration	NOUN
gs-3921	147	15	inherent	inherent	ADJ
gs-3921	147	16	to	to	ADP
gs-3921	147	17	the	the	DET
gs-3921	147	18	adoption	adoption	NOUN
gs-3921	147	19	of	of	ADP
gs-3921	147	20	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	147	21	and	and	CCONJ
gs-3921	147	22	patient	patient	NOUN
gs-3921	147	23	-	-	PUNCT
gs-3921	147	24	centered	center	VERB
gs-3921	147	25	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	147	26	,	,	PUNCT
gs-3921	147	27	emphasizing	emphasize	VERB
gs-3921	147	28	the	the	DET
gs-3921	147	29	need	need	NOUN
gs-3921	147	30	for	for	ADP
gs-3921	147	31	frameworks	framework	NOUN
gs-3921	147	32	that	that	PRON
gs-3921	147	33	protect	protect	VERB
gs-3921	147	34	patient	patient	ADJ
gs-3921	147	35	autonomy	autonomy	NOUN
gs-3921	147	36	,	,	PUNCT
gs-3921	147	37	privacy	privacy	NOUN
gs-3921	147	38	,	,	PUNCT
gs-3921	147	39	and	and	CCONJ
gs-3921	147	40	equity	equity	NOUN
gs-3921	147	41	.	.	PUNCT
gs-3921	148	1	recognizing	recognize	VERB
gs-3921	148	2	the	the	DET
gs-3921	148	3	global	global	ADJ
gs-3921	148	4	diversity	diversity	NOUN
gs-3921	148	5	in	in	ADP
gs-3921	148	6	healthcare	healthcare	PROPN
gs-3921	148	7	infrastructure	infrastructure	NOUN
gs-3921	148	8	and	and	CCONJ
gs-3921	148	9	genetic	genetic	ADJ
gs-3921	148	10	backgrounds	background	NOUN
gs-3921	148	11	,	,	PUNCT
gs-3921	148	12	the	the	DET
gs-3921	148	13	study	study	NOUN
gs-3921	148	14	aims	aim	VERB
gs-3921	148	15	to	to	PART
gs-3921	148	16	underscore	underscore	VERB
gs-3921	148	17	the	the	DET
gs-3921	148	18	importance	importance	NOUN
gs-3921	148	19	of	of	ADP
gs-3921	148	20	inclusive	inclusive	ADJ
gs-3921	148	21	research	research	NOUN
gs-3921	148	22	and	and	CCONJ
gs-3921	148	23	policy	policy	NOUN
gs-3921	148	24	development	development	NOUN
gs-3921	148	25	that	that	PRON
gs-3921	148	26	ensure	ensure	VERB
gs-3921	148	27	equitable	equitable	ADJ
gs-3921	148	28	benefits	benefit	NOUN
gs-3921	148	29	across	across	ADP
gs-3921	148	30	populations	population	NOUN
gs-3921	148	31	.	.	PUNCT
gs-3921	149	1	ultimately	ultimately	ADV
gs-3921	149	2	,	,	PUNCT
gs-3921	149	3	this	this	DET
gs-3921	149	4	comprehensive	comprehensive	ADJ
gs-3921	149	5	analysis	analysis	NOUN
gs-3921	149	6	intends	intend	VERB
gs-3921	149	7	to	to	PART
gs-3921	149	8	provide	provide	VERB
gs-3921	149	9	a	a	DET
gs-3921	149	10	cohesive	cohesive	ADJ
gs-3921	149	11	and	and	CCONJ
gs-3921	149	12	multidisciplinary	multidisciplinary	ADJ
gs-3921	149	13	perspective	perspective	NOUN
gs-3921	149	14	that	that	PRON
gs-3921	149	15	informs	inform	VERB
gs-3921	149	16	clinicians	clinician	NOUN
gs-3921	149	17	,	,	PUNCT
gs-3921	149	18	researchers	researcher	NOUN
gs-3921	149	19	,	,	PUNCT
gs-3921	149	20	policymakers	policymaker	NOUN
gs-3921	149	21	,	,	PUNCT
gs-3921	149	22	and	and	CCONJ
gs-3921	149	23	georgian	georgian	ADJ
gs-3921	149	24	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	149	25	მეცნიერები	მეცნიერები	NOUN
gs-3921	149	26	ტ.	ტ.	VERB
gs-3921	149	27	7	7	NUM
gs-3921	149	28	n	n	DET
gs-3921	149	29	3	3	NUM
gs-3921	149	30	,	,	PUNCT
gs-3921	149	31	2025	2025	NUM
gs-3921	149	32	227	227	NUM
gs-3921	149	33	patients	patient	NOUN
gs-3921	149	34	alike	alike	ADV
gs-3921	149	35	.	.	PUNCT
gs-3921	150	1	by	by	ADP
gs-3921	150	2	fostering	foster	VERB
gs-3921	150	3	a	a	DET
gs-3921	150	4	deeper	deep	ADJ
gs-3921	150	5	understanding	understanding	NOUN
gs-3921	150	6	of	of	ADP
gs-3921	150	7	the	the	DET
gs-3921	150	8	complex	complex	ADJ
gs-3921	150	9	interplay	interplay	NOUN
gs-3921	150	10	between	between	ADP
gs-3921	150	11	genetics	genetic	NOUN
gs-3921	150	12	,	,	PUNCT
gs-3921	150	13	clinical	clinical	ADJ
gs-3921	150	14	care	care	NOUN
gs-3921	150	15	,	,	PUNCT
gs-3921	150	16	and	and	CCONJ
gs-3921	150	17	medication	medication	NOUN
gs-3921	150	18	safety	safety	NOUN
gs-3921	150	19	,	,	PUNCT
gs-3921	150	20	the	the	DET
gs-3921	150	21	study	study	NOUN
gs-3921	150	22	seeks	seek	VERB
gs-3921	150	23	to	to	PART
gs-3921	150	24	contribute	contribute	VERB
gs-3921	150	25	to	to	ADP
gs-3921	150	26	the	the	DET
gs-3921	150	27	advancement	advancement	NOUN
gs-3921	150	28	of	of	ADP
gs-3921	150	29	personalized	personalized	ADJ
gs-3921	150	30	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	150	31	,	,	PUNCT
gs-3921	150	32	reduce	reduce	VERB
gs-3921	150	33	the	the	DET
gs-3921	150	34	incidence	incidence	NOUN
gs-3921	150	35	and	and	CCONJ
gs-3921	150	36	impact	impact	NOUN
gs-3921	150	37	of	of	ADP
gs-3921	150	38	adverse	adverse	ADJ
gs-3921	150	39	drug	drug	NOUN
gs-3921	150	40	reactions	reaction	NOUN
gs-3921	150	41	,	,	PUNCT
gs-3921	150	42	and	and	CCONJ
gs-3921	150	43	promote	promote	VERB
gs-3921	150	44	a	a	DET
gs-3921	150	45	more	more	ADV
gs-3921	150	46	responsive	responsive	ADJ
gs-3921	150	47	and	and	CCONJ
gs-3921	150	48	ethical	ethical	ADJ
gs-3921	150	49	healthcare	healthcare	NOUN
gs-3921	150	50	environment	environment	NOUN
gs-3921	150	51	.	.	PUNCT
gs-3921	151	1	methodology	methodology	NOUN
gs-3921	151	2	the	the	DET
gs-3921	151	3	comprehensive	comprehensive	ADJ
gs-3921	151	4	analysis	analysis	NOUN
gs-3921	151	5	employed	employ	VERB
gs-3921	151	6	a	a	DET
gs-3921	151	7	multidisciplinary	multidisciplinary	ADJ
gs-3921	151	8	approach	approach	NOUN
gs-3921	151	9	combining	combine	VERB
gs-3921	151	10	systematic	systematic	ADJ
gs-3921	151	11	literature	literature	PROPN
gs-3921	151	12	review	review	PROPN
gs-3921	151	13	,	,	PUNCT
gs-3921	151	14	data	datum	NOUN
gs-3921	151	15	synthesis	synthesis	NOUN
gs-3921	151	16	,	,	PUNCT
gs-3921	151	17	and	and	CCONJ
gs-3921	151	18	critical	critical	ADJ
gs-3921	151	19	appraisal	appraisal	NOUN
gs-3921	151	20	of	of	ADP
gs-3921	151	21	current	current	ADJ
gs-3921	151	22	research	research	NOUN
gs-3921	151	23	and	and	CCONJ
gs-3921	151	24	clinical	clinical	ADJ
gs-3921	151	25	practices	practice	NOUN
gs-3921	151	26	related	relate	VERB
gs-3921	151	27	to	to	ADP
gs-3921	151	28	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	151	29	,	,	PUNCT
gs-3921	151	30	patient	patient	NOUN
gs-3921	151	31	-	-	PUNCT
gs-3921	151	32	centered	center	VERB
gs-3921	151	33	care	care	NOUN
gs-3921	151	34	,	,	PUNCT
gs-3921	151	35	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	151	36	,	,	PUNCT
gs-3921	151	37	and	and	CCONJ
gs-3921	151	38	medication	medication	NOUN
gs-3921	151	39	-	-	PUNCT
gs-3921	151	40	induced	induce	VERB
gs-3921	151	41	adverse	adverse	ADJ
gs-3921	151	42	effects	effect	NOUN
gs-3921	151	43	.	.	PUNCT
gs-3921	152	1	a	a	DET
gs-3921	152	2	rigorous	rigorous	ADJ
gs-3921	152	3	search	search	NOUN
gs-3921	152	4	strategy	strategy	NOUN
gs-3921	152	5	was	be	AUX
gs-3921	152	6	designed	design	VERB
gs-3921	152	7	to	to	PART
gs-3921	152	8	capture	capture	VERB
gs-3921	152	9	a	a	DET
gs-3921	152	10	broad	broad	ADJ
gs-3921	152	11	spectrum	spectrum	NOUN
gs-3921	152	12	of	of	ADP
gs-3921	152	13	relevant	relevant	ADJ
gs-3921	152	14	scientific	scientific	ADJ
gs-3921	152	15	publications	publication	NOUN
gs-3921	152	16	,	,	PUNCT
gs-3921	152	17	clinical	clinical	ADJ
gs-3921	152	18	guidelines	guideline	NOUN
gs-3921	152	19	,	,	PUNCT
gs-3921	152	20	regulatory	regulatory	ADJ
gs-3921	152	21	documents	document	NOUN
gs-3921	152	22	,	,	PUNCT
gs-3921	152	23	and	and	CCONJ
gs-3921	152	24	real	real	ADJ
gs-3921	152	25	-	-	PUNCT
gs-3921	152	26	world	world	NOUN
gs-3921	152	27	evidence	evidence	NOUN
gs-3921	152	28	studies	study	NOUN
gs-3921	152	29	.	.	PUNCT
gs-3921	153	1	major	major	ADJ
gs-3921	153	2	electronic	electronic	ADJ
gs-3921	153	3	databases	database	NOUN
gs-3921	153	4	,	,	PUNCT
gs-3921	153	5	including	include	VERB
gs-3921	153	6	pubmed	pubmed	PROPN
gs-3921	153	7	,	,	PUNCT
gs-3921	153	8	scopus	scopus	PROPN
gs-3921	153	9	,	,	PUNCT
gs-3921	153	10	web	web	NOUN
gs-3921	153	11	of	of	ADP
gs-3921	153	12	science	science	NOUN
gs-3921	153	13	,	,	PUNCT
gs-3921	153	14	and	and	CCONJ
gs-3921	153	15	embase	embase	NOUN
gs-3921	153	16	,	,	PUNCT
gs-3921	153	17	were	be	AUX
gs-3921	153	18	queried	query	VERB
gs-3921	153	19	using	use	VERB
gs-3921	153	20	carefully	carefully	ADV
gs-3921	153	21	constructed	construct	VERB
gs-3921	153	22	keywords	keyword	NOUN
gs-3921	153	23	and	and	CCONJ
gs-3921	153	24	medical	medical	ADJ
gs-3921	153	25	subject	subject	NOUN
gs-3921	153	26	headings	heading	NOUN
gs-3921	153	27	(	(	PUNCT
gs-3921	153	28	mesh	mesh	NOUN
gs-3921	153	29	)	)	PUNCT
gs-3921	153	30	terms	term	NOUN
gs-3921	153	31	that	that	PRON
gs-3921	153	32	encompassed	encompass	VERB
gs-3921	153	33	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	153	34	,	,	PUNCT
gs-3921	153	35	adverse	adverse	ADJ
gs-3921	153	36	drug	drug	NOUN
gs-3921	153	37	reactions	reaction	NOUN
gs-3921	153	38	,	,	PUNCT
gs-3921	153	39	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	153	40	,	,	PUNCT
gs-3921	153	41	patient	patient	NOUN
gs-3921	153	42	-	-	PUNCT
gs-3921	153	43	centered	center	VERB
gs-3921	153	44	care	care	NOUN
gs-3921	153	45	,	,	PUNCT
gs-3921	153	46	and	and	CCONJ
gs-3921	153	47	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	153	48	management	management	NOUN
gs-3921	153	49	.	.	PUNCT
gs-3921	154	1	the	the	DET
gs-3921	154	2	search	search	NOUN
gs-3921	154	3	encompassed	encompass	VERB
gs-3921	154	4	articles	article	NOUN
gs-3921	154	5	published	publish	VERB
gs-3921	154	6	in	in	ADP
gs-3921	154	7	multiple	multiple	ADJ
gs-3921	154	8	languages	language	NOUN
gs-3921	154	9	and	and	CCONJ
gs-3921	154	10	across	across	ADP
gs-3921	154	11	diverse	diverse	ADJ
gs-3921	154	12	geographic	geographic	ADJ
gs-3921	154	13	regions	region	NOUN
gs-3921	154	14	to	to	PART
gs-3921	154	15	ensure	ensure	VERB
gs-3921	154	16	inclusivity	inclusivity	NOUN
gs-3921	154	17	and	and	CCONJ
gs-3921	154	18	comprehensiveness	comprehensiveness	NOUN
gs-3921	154	19	.	.	PUNCT
gs-3921	155	1	inclusion	inclusion	NOUN
gs-3921	155	2	criteria	criterion	NOUN
gs-3921	155	3	focused	focus	VERB
gs-3921	155	4	on	on	ADP
gs-3921	155	5	peer	peer	NOUN
gs-3921	155	6	-	-	PUNCT
gs-3921	155	7	reviewed	review	VERB
gs-3921	155	8	original	original	ADJ
gs-3921	155	9	research	research	NOUN
gs-3921	155	10	studies	study	NOUN
gs-3921	155	11	,	,	PUNCT
gs-3921	155	12	systematic	systematic	ADJ
gs-3921	155	13	reviews	review	NOUN
gs-3921	155	14	,	,	PUNCT
gs-3921	155	15	meta	meta	NOUN
gs-3921	155	16	-	-	PUNCT
gs-3921	155	17	analyses	analysis	NOUN
gs-3921	155	18	,	,	PUNCT
gs-3921	155	19	clinical	clinical	ADJ
gs-3921	155	20	practice	practice	NOUN
gs-3921	155	21	guidelines	guideline	NOUN
gs-3921	155	22	,	,	PUNCT
gs-3921	155	23	and	and	CCONJ
gs-3921	155	24	policy	policy	NOUN
gs-3921	155	25	papers	paper	NOUN
gs-3921	155	26	that	that	PRON
gs-3921	155	27	addressed	address	VERB
gs-3921	155	28	genetic	genetic	ADJ
gs-3921	155	29	determinants	determinant	NOUN
gs-3921	155	30	of	of	ADP
gs-3921	155	31	drug	drug	NOUN
gs-3921	155	32	response	response	NOUN
gs-3921	155	33	,	,	PUNCT
gs-3921	155	34	strategies	strategy	NOUN
gs-3921	155	35	for	for	ADP
gs-3921	155	36	adverse	adverse	ADJ
gs-3921	155	37	effect	effect	NOUN
gs-3921	155	38	prevention	prevention	NOUN
gs-3921	155	39	and	and	CCONJ
gs-3921	155	40	management	management	NOUN
gs-3921	155	41	,	,	PUNCT
gs-3921	155	42	and	and	CCONJ
gs-3921	155	43	frameworks	framework	NOUN
gs-3921	155	44	for	for	ADP
gs-3921	155	45	integrating	integrate	VERB
gs-3921	155	46	patient	patient	ADJ
gs-3921	155	47	preferences	preference	NOUN
gs-3921	155	48	into	into	ADP
gs-3921	155	49	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	155	50	.	.	PUNCT
gs-3921	156	1	excluded	exclude	VERB
gs-3921	156	2	from	from	ADP
gs-3921	156	3	consideration	consideration	NOUN
gs-3921	156	4	were	be	AUX
gs-3921	156	5	studies	study	NOUN
gs-3921	156	6	lacking	lack	VERB
gs-3921	156	7	sufficient	sufficient	ADJ
gs-3921	156	8	methodological	methodological	ADJ
gs-3921	156	9	rigor	rigor	NOUN
gs-3921	156	10	,	,	PUNCT
gs-3921	156	11	case	case	NOUN
gs-3921	156	12	reports	report	NOUN
gs-3921	156	13	with	with	ADP
gs-3921	156	14	limited	limited	ADJ
gs-3921	156	15	generalizability	generalizability	NOUN
gs-3921	156	16	,	,	PUNCT
gs-3921	156	17	and	and	CCONJ
gs-3921	156	18	publications	publication	NOUN
gs-3921	156	19	unrelated	unrelated	ADJ
gs-3921	156	20	to	to	ADP
gs-3921	156	21	the	the	DET
gs-3921	156	22	core	core	ADJ
gs-3921	156	23	thematic	thematic	ADJ
gs-3921	156	24	areas	area	NOUN
gs-3921	156	25	.	.	PUNCT
gs-3921	157	1	data	datum	NOUN
gs-3921	157	2	extraction	extraction	NOUN
gs-3921	157	3	involved	involve	VERB
gs-3921	157	4	detailed	detailed	ADJ
gs-3921	157	5	collection	collection	NOUN
gs-3921	157	6	of	of	ADP
gs-3921	157	7	study	study	NOUN
gs-3921	157	8	design	design	NOUN
gs-3921	157	9	,	,	PUNCT
gs-3921	157	10	population	population	NOUN
gs-3921	157	11	characteristics	characteristic	NOUN
gs-3921	157	12	,	,	PUNCT
gs-3921	157	13	genetic	genetic	ADJ
gs-3921	157	14	markers	marker	NOUN
gs-3921	157	15	investigated	investigate	VERB
gs-3921	157	16	,	,	PUNCT
gs-3921	157	17	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	157	18	methodologies	methodology	NOUN
gs-3921	157	19	,	,	PUNCT
gs-3921	157	20	patient	patient	ADJ
gs-3921	157	21	engagement	engagement	NOUN
gs-3921	157	22	practices	practice	NOUN
gs-3921	157	23	,	,	PUNCT
gs-3921	157	24	and	and	CCONJ
gs-3921	157	25	therapeutic	therapeutic	ADJ
gs-3921	157	26	outcomes	outcome	NOUN
gs-3921	157	27	.	.	PUNCT
gs-3921	158	1	the	the	DET
gs-3921	158	2	analysis	analysis	NOUN
gs-3921	158	3	integrated	integrate	VERB
gs-3921	158	4	qualitative	qualitative	NOUN
gs-3921	158	5	and	and	CCONJ
gs-3921	158	6	quantitative	quantitative	ADJ
gs-3921	158	7	evidence	evidence	NOUN
gs-3921	158	8	to	to	PART
gs-3921	158	9	identify	identify	VERB
gs-3921	158	10	patterns	pattern	NOUN
gs-3921	158	11	,	,	PUNCT
gs-3921	158	12	consensus	consensus	NOUN
gs-3921	158	13	,	,	PUNCT
gs-3921	158	14	and	and	CCONJ
gs-3921	158	15	discrepancies	discrepancy	NOUN
gs-3921	158	16	within	within	ADP
gs-3921	158	17	the	the	DET
gs-3921	158	18	literature	literature	NOUN
gs-3921	158	19	.	.	PUNCT
gs-3921	159	1	particular	particular	ADJ
gs-3921	159	2	emphasis	emphasis	NOUN
gs-3921	159	3	was	be	AUX
gs-3921	159	4	placed	place	VERB
gs-3921	159	5	on	on	ADP
gs-3921	159	6	the	the	DET
gs-3921	159	7	clinical	clinical	ADJ
gs-3921	159	8	utility	utility	NOUN
gs-3921	159	9	and	and	CCONJ
gs-3921	159	10	implementation	implementation	NOUN
gs-3921	159	11	challenges	challenge	NOUN
gs-3921	159	12	of	of	ADP
gs-3921	159	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	159	14	testing	testing	NOUN
gs-3921	159	15	,	,	PUNCT
gs-3921	159	16	the	the	DET
gs-3921	159	17	effectiveness	effectiveness	NOUN
gs-3921	159	18	of	of	ADP
gs-3921	159	19	patient	patient	NOUN
gs-3921	159	20	-	-	PUNCT
gs-3921	159	21	centered	center	VERB
gs-3921	159	22	interventions	intervention	NOUN
gs-3921	159	23	in	in	ADP
gs-3921	159	24	improving	improve	VERB
gs-3921	159	25	medication	medication	NOUN
gs-3921	159	26	safety	safety	NOUN
gs-3921	159	27	,	,	PUNCT
gs-3921	159	28	and	and	CCONJ
gs-3921	159	29	the	the	DET
gs-3921	159	30	evolving	evolve	VERB
gs-3921	159	31	role	role	NOUN
gs-3921	159	32	of	of	ADP
gs-3921	159	33	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	159	34	systems	system	NOUN
gs-3921	159	35	in	in	ADP
gs-3921	159	36	real	real	ADJ
gs-3921	159	37	-	-	PUNCT
gs-3921	159	38	world	world	NOUN
gs-3921	159	39	settings	setting	NOUN
gs-3921	159	40	.	.	PUNCT
gs-3921	160	1	comparative	comparative	ADJ
gs-3921	160	2	evaluation	evaluation	NOUN
gs-3921	160	3	of	of	ADP
gs-3921	160	4	international	international	ADJ
gs-3921	160	5	regulatory	regulatory	ADJ
gs-3921	160	6	frameworks	framework	NOUN
gs-3921	160	7	and	and	CCONJ
gs-3921	160	8	ethical	ethical	ADJ
gs-3921	160	9	guidelines	guideline	NOUN
gs-3921	160	10	further	far	ADV
gs-3921	160	11	enriched	enrich	VERB
gs-3921	160	12	the	the	DET
gs-3921	160	13	contextual	contextual	ADJ
gs-3921	160	14	understanding	understanding	NOUN
gs-3921	160	15	.	.	PUNCT
gs-3921	161	1	in	in	ADP
gs-3921	161	2	addition	addition	NOUN
gs-3921	161	3	to	to	ADP
gs-3921	161	4	literature	literature	PROPN
gs-3921	161	5	review	review	PROPN
gs-3921	161	6	,	,	PUNCT
gs-3921	161	7	the	the	DET
gs-3921	161	8	study	study	NOUN
gs-3921	161	9	examined	examine	VERB
gs-3921	161	10	case	case	NOUN
gs-3921	161	11	studies	study	NOUN
gs-3921	161	12	and	and	CCONJ
gs-3921	161	13	exemplar	exemplar	ADJ
gs-3921	161	14	models	model	NOUN
gs-3921	161	15	from	from	ADP
gs-3921	161	16	diverse	diverse	ADJ
gs-3921	161	17	healthcare	healthcare	NOUN
gs-3921	161	18	systems	system	NOUN
gs-3921	161	19	to	to	PART
gs-3921	161	20	elucidate	elucidate	VERB
gs-3921	161	21	practical	practical	ADJ
gs-3921	161	22	applications	application	NOUN
gs-3921	161	23	and	and	CCONJ
gs-3921	161	24	lessons	lesson	NOUN
gs-3921	161	25	learned	learn	VERB
gs-3921	161	26	.	.	PUNCT
gs-3921	162	1	these	these	DET
gs-3921	162	2	case	case	NOUN
gs-3921	162	3	studies	study	NOUN
gs-3921	162	4	illustrated	illustrate	VERB
gs-3921	162	5	successful	successful	ADJ
gs-3921	162	6	integration	integration	NOUN
gs-3921	162	7	of	of	ADP
gs-3921	162	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	162	9	data	datum	NOUN
gs-3921	162	10	into	into	ADP
gs-3921	162	11	clinical	clinical	ADJ
gs-3921	162	12	workflows	workflow	NOUN
gs-3921	162	13	,	,	PUNCT
gs-3921	162	14	multidisciplinary	multidisciplinary	ADJ
gs-3921	162	15	collaboration	collaboration	NOUN
gs-3921	162	16	,	,	PUNCT
gs-3921	162	17	and	and	CCONJ
gs-3921	162	18	innovative	innovative	ADJ
gs-3921	162	19	patient	patient	ADJ
gs-3921	162	20	engagement	engagement	NOUN
gs-3921	162	21	strategies	strategy	NOUN
gs-3921	162	22	.	.	PUNCT
gs-3921	163	1	insights	insight	NOUN
gs-3921	163	2	were	be	AUX
gs-3921	163	3	also	also	ADV
gs-3921	163	4	drawn	draw	VERB
gs-3921	163	5	from	from	ADP
gs-3921	163	6	ongoing	ongoing	ADJ
gs-3921	163	7	clinical	clinical	ADJ
gs-3921	163	8	trials	trial	NOUN
gs-3921	163	9	and	and	CCONJ
gs-3921	163	10	pilot	pilot	NOUN
gs-3921	163	11	programs	program	NOUN
gs-3921	163	12	georgian	georgian	ADJ
gs-3921	163	13	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	163	14	მეცნიერები	მეცნიერები	NOUN
gs-3921	163	15	ტ.	ტ.	VERB
gs-3921	163	16	7	7	NUM
gs-3921	163	17	n	n	PRON
gs-3921	163	18	3	3	NUM
gs-3921	163	19	,	,	PUNCT
gs-3921	163	20	2025	2025	NUM
gs-3921	163	21	228	228	NUM
gs-3921	163	22	investigating	investigate	VERB
gs-3921	163	23	novel	novel	ADJ
gs-3921	163	24	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	163	25	markers	marker	NOUN
gs-3921	163	26	,	,	PUNCT
gs-3921	163	27	digital	digital	ADJ
gs-3921	163	28	health	health	NOUN
gs-3921	163	29	technologies	technology	NOUN
gs-3921	163	30	,	,	PUNCT
gs-3921	163	31	and	and	CCONJ
gs-3921	163	32	active	active	ADJ
gs-3921	163	33	safety	safety	NOUN
gs-3921	163	34	monitoring	monitor	VERB
gs-3921	163	35	techniques	technique	NOUN
gs-3921	163	36	.	.	PUNCT
gs-3921	164	1	throughout	throughout	ADP
gs-3921	164	2	the	the	DET
gs-3921	164	3	analysis	analysis	NOUN
gs-3921	164	4	,	,	PUNCT
gs-3921	164	5	a	a	DET
gs-3921	164	6	critical	critical	ADJ
gs-3921	164	7	lens	lens	NOUN
gs-3921	164	8	was	be	AUX
gs-3921	164	9	applied	apply	VERB
gs-3921	164	10	to	to	PART
gs-3921	164	11	assess	assess	VERB
gs-3921	164	12	the	the	DET
gs-3921	164	13	quality	quality	NOUN
gs-3921	164	14	and	and	CCONJ
gs-3921	164	15	relevance	relevance	NOUN
gs-3921	164	16	of	of	ADP
gs-3921	164	17	evidence	evidence	NOUN
gs-3921	164	18	,	,	PUNCT
gs-3921	164	19	identify	identify	VERB
gs-3921	164	20	gaps	gap	NOUN
gs-3921	164	21	in	in	ADP
gs-3921	164	22	knowledge	knowledge	NOUN
gs-3921	164	23	,	,	PUNCT
gs-3921	164	24	and	and	CCONJ
gs-3921	164	25	highlight	highlight	VERB
gs-3921	164	26	areas	area	NOUN
gs-3921	164	27	requiring	require	VERB
gs-3921	164	28	further	further	ADJ
gs-3921	164	29	research	research	NOUN
gs-3921	164	30	or	or	CCONJ
gs-3921	164	31	policy	policy	NOUN
gs-3921	164	32	development	development	NOUN
gs-3921	164	33	.	.	PUNCT
gs-3921	165	1	ethical	ethical	ADJ
gs-3921	165	2	considerations	consideration	NOUN
gs-3921	165	3	were	be	AUX
gs-3921	165	4	incorporated	incorporate	VERB
gs-3921	165	5	by	by	ADP
gs-3921	165	6	evaluating	evaluate	VERB
gs-3921	165	7	how	how	SCONJ
gs-3921	165	8	studies	study	NOUN
gs-3921	165	9	addressed	address	VERB
gs-3921	165	10	informed	informed	ADJ
gs-3921	165	11	consent	consent	NOUN
gs-3921	165	12	,	,	PUNCT
gs-3921	165	13	data	data	NOUN
gs-3921	165	14	privacy	privacy	NOUN
gs-3921	165	15	,	,	PUNCT
gs-3921	165	16	equity	equity	NOUN
gs-3921	165	17	of	of	ADP
gs-3921	165	18	access	access	NOUN
gs-3921	165	19	,	,	PUNCT
gs-3921	165	20	and	and	CCONJ
gs-3921	165	21	potential	potential	ADJ
gs-3921	165	22	societal	societal	ADJ
gs-3921	165	23	implications	implication	NOUN
gs-3921	165	24	.	.	PUNCT
gs-3921	166	1	the	the	DET
gs-3921	166	2	methodological	methodological	ADJ
gs-3921	166	3	framework	framework	NOUN
gs-3921	166	4	ensured	ensure	VERB
gs-3921	166	5	a	a	DET
gs-3921	166	6	balanced	balanced	ADJ
gs-3921	166	7	and	and	CCONJ
gs-3921	166	8	nuanced	nuanced	ADJ
gs-3921	166	9	synthesis	synthesis	NOUN
gs-3921	166	10	that	that	PRON
gs-3921	166	11	informs	inform	VERB
gs-3921	166	12	both	both	PRON
gs-3921	166	13	scientific	scientific	ADJ
gs-3921	166	14	inquiry	inquiry	NOUN
gs-3921	166	15	and	and	CCONJ
gs-3921	166	16	practical	practical	ADJ
gs-3921	166	17	implementation	implementation	NOUN
gs-3921	166	18	.	.	PUNCT
gs-3921	167	1	overall	overall	ADV
gs-3921	167	2	,	,	PUNCT
gs-3921	167	3	this	this	DET
gs-3921	167	4	methodology	methodology	NOUN
gs-3921	167	5	aimed	aim	VERB
gs-3921	167	6	to	to	PART
gs-3921	167	7	provide	provide	VERB
gs-3921	167	8	a	a	DET
gs-3921	167	9	robust	robust	ADJ
gs-3921	167	10	and	and	CCONJ
gs-3921	167	11	comprehensive	comprehensive	ADJ
gs-3921	167	12	foundation	foundation	NOUN
gs-3921	167	13	for	for	ADP
gs-3921	167	14	advancing	advance	VERB
gs-3921	167	15	understanding	understanding	NOUN
gs-3921	167	16	and	and	CCONJ
gs-3921	167	17	application	application	NOUN
gs-3921	167	18	of	of	ADP
gs-3921	167	19	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	167	20	and	and	CCONJ
gs-3921	167	21	patient	patient	NOUN
gs-3921	167	22	-	-	PUNCT
gs-3921	167	23	centered	center	VERB
gs-3921	167	24	approaches	approach	NOUN
gs-3921	167	25	to	to	ADP
gs-3921	167	26	medication	medication	NOUN
gs-3921	167	27	safety	safety	NOUN
gs-3921	167	28	,	,	PUNCT
gs-3921	167	29	thereby	thereby	ADV
gs-3921	167	30	supporting	support	VERB
gs-3921	167	31	more	more	ADV
gs-3921	167	32	effective	effective	ADJ
gs-3921	167	33	,	,	PUNCT
gs-3921	167	34	equitable	equitable	ADJ
gs-3921	167	35	,	,	PUNCT
gs-3921	167	36	and	and	CCONJ
gs-3921	167	37	personalized	personalize	VERB
gs-3921	167	38	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	167	39	management	management	NOUN
gs-3921	167	40	.	.	PUNCT
gs-3921	168	1	results	result	NOUN
gs-3921	168	2	and	and	CCONJ
gs-3921	168	3	discussion	discussion	VERB
gs-3921	168	4	the	the	DET
gs-3921	168	5	synthesis	synthesis	NOUN
gs-3921	168	6	of	of	ADP
gs-3921	168	7	the	the	DET
gs-3921	168	8	reviewed	review	VERB
gs-3921	168	9	literature	literature	NOUN
gs-3921	168	10	and	and	CCONJ
gs-3921	168	11	case	case	NOUN
gs-3921	168	12	analyses	analysis	NOUN
gs-3921	168	13	reveals	reveal	VERB
gs-3921	168	14	a	a	DET
gs-3921	168	15	complex	complex	ADJ
gs-3921	168	16	and	and	CCONJ
gs-3921	168	17	rapidly	rapidly	ADV
gs-3921	168	18	evolving	evolve	VERB
gs-3921	168	19	landscape	landscape	NOUN
gs-3921	168	20	in	in	ADP
gs-3921	168	21	the	the	DET
gs-3921	168	22	integration	integration	NOUN
gs-3921	168	23	of	of	ADP
gs-3921	168	24	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	168	25	and	and	CCONJ
gs-3921	168	26	patient	patient	NOUN
gs-3921	168	27	-	-	PUNCT
gs-3921	168	28	centered	center	VERB
gs-3921	168	29	care	care	NOUN
gs-3921	168	30	to	to	PART
gs-3921	168	31	mitigate	mitigate	VERB
gs-3921	168	32	medication	medication	NOUN
gs-3921	168	33	-	-	PUNCT
gs-3921	168	34	induced	induce	VERB
gs-3921	168	35	adverse	adverse	ADJ
gs-3921	168	36	effects	effect	NOUN
gs-3921	168	37	.	.	PUNCT
gs-3921	169	1	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	169	2	testing	testing	NOUN
gs-3921	169	3	has	have	AUX
gs-3921	169	4	demonstrated	demonstrate	VERB
gs-3921	169	5	significant	significant	ADJ
gs-3921	169	6	promise	promise	NOUN
gs-3921	169	7	in	in	ADP
gs-3921	169	8	identifying	identify	VERB
gs-3921	169	9	individuals	individual	NOUN
gs-3921	169	10	at	at	ADP
gs-3921	169	11	heightened	heightened	ADJ
gs-3921	169	12	risk	risk	NOUN
gs-3921	169	13	for	for	ADP
gs-3921	169	14	specific	specific	ADJ
gs-3921	169	15	toxicities	toxicity	NOUN
gs-3921	169	16	,	,	PUNCT
gs-3921	169	17	particularly	particularly	ADV
gs-3921	169	18	where	where	SCONJ
gs-3921	169	19	well	well	ADV
gs-3921	169	20	-	-	PUNCT
gs-3921	169	21	established	establish	VERB
gs-3921	169	22	gene	gene	NOUN
gs-3921	169	23	-	-	PUNCT
gs-3921	169	24	drug	drug	NOUN
gs-3921	169	25	interactions	interaction	NOUN
gs-3921	169	26	exist	exist	VERB
gs-3921	169	27	.	.	PUNCT
gs-3921	170	1	for	for	ADP
gs-3921	170	2	example	example	NOUN
gs-3921	170	3	,	,	PUNCT
gs-3921	170	4	the	the	DET
gs-3921	170	5	use	use	NOUN
gs-3921	170	6	of	of	ADP
gs-3921	170	7	hla	hla	NOUN
gs-3921	170	8	genotyping	genotype	VERB
gs-3921	170	9	to	to	PART
gs-3921	170	10	predict	predict	VERB
gs-3921	170	11	hypersensitivity	hypersensitivity	NOUN
gs-3921	170	12	reactions	reaction	NOUN
gs-3921	170	13	to	to	ADP
gs-3921	170	14	drugs	drug	NOUN
gs-3921	170	15	such	such	ADJ
gs-3921	170	16	as	as	ADP
gs-3921	170	17	carbamazepine	carbamazepine	NOUN
gs-3921	170	18	and	and	CCONJ
gs-3921	170	19	abacavir	abacavir	NOUN
gs-3921	170	20	has	have	AUX
gs-3921	170	21	become	become	VERB
gs-3921	170	22	an	an	DET
gs-3921	170	23	exemplar	exemplar	NOUN
gs-3921	170	24	of	of	ADP
gs-3921	170	25	precision	precision	NOUN
gs-3921	170	26	medicine	medicine	NOUN
gs-3921	170	27	translating	translate	VERB
gs-3921	170	28	into	into	ADP
gs-3921	170	29	improved	improved	ADJ
gs-3921	170	30	patient	patient	ADJ
gs-3921	170	31	safety	safety	NOUN
gs-3921	170	32	.	.	PUNCT
gs-3921	171	1	similarly	similarly	ADV
gs-3921	171	2	,	,	PUNCT
gs-3921	171	3	variants	variant	NOUN
gs-3921	171	4	in	in	ADP
gs-3921	171	5	cytochrome	cytochrome	ADJ
gs-3921	171	6	p450	p450	NUM
gs-3921	171	7	enzymes	enzyme	NOUN
gs-3921	171	8	have	have	AUX
gs-3921	171	9	been	be	AUX
gs-3921	171	10	reliably	reliably	ADV
gs-3921	171	11	linked	link	VERB
gs-3921	171	12	to	to	ADP
gs-3921	171	13	altered	alter	VERB
gs-3921	171	14	metabolism	metabolism	NOUN
gs-3921	171	15	of	of	ADP
gs-3921	171	16	numerous	numerous	ADJ
gs-3921	171	17	medications	medication	NOUN
gs-3921	171	18	,	,	PUNCT
gs-3921	171	19	informing	inform	VERB
gs-3921	171	20	dose	dose	NOUN
gs-3921	171	21	adjustments	adjustment	NOUN
gs-3921	171	22	that	that	PRON
gs-3921	171	23	reduce	reduce	VERB
gs-3921	171	24	toxicity	toxicity	NOUN
gs-3921	171	25	and	and	CCONJ
gs-3921	171	26	enhance	enhance	VERB
gs-3921	171	27	therapeutic	therapeutic	ADJ
gs-3921	171	28	outcomes	outcome	NOUN
gs-3921	171	29	.	.	PUNCT
gs-3921	172	1	despite	despite	SCONJ
gs-3921	172	2	these	these	DET
gs-3921	172	3	advances	advance	NOUN
gs-3921	172	4	,	,	PUNCT
gs-3921	172	5	widespread	widespread	ADJ
gs-3921	172	6	clinical	clinical	ADJ
gs-3921	172	7	implementation	implementation	NOUN
gs-3921	172	8	remains	remain	VERB
gs-3921	172	9	limited	limit	VERB
gs-3921	172	10	by	by	ADP
gs-3921	172	11	multifaceted	multifaceted	ADJ
gs-3921	172	12	barriers	barrier	NOUN
gs-3921	172	13	.	.	PUNCT
gs-3921	173	1	a	a	DET
gs-3921	173	2	recurrent	recurrent	ADJ
gs-3921	173	3	theme	theme	NOUN
gs-3921	173	4	across	across	ADP
gs-3921	173	5	studies	study	NOUN
gs-3921	173	6	is	be	AUX
gs-3921	173	7	the	the	DET
gs-3921	173	8	inconsistent	inconsistent	ADJ
gs-3921	173	9	availability	availability	NOUN
gs-3921	173	10	of	of	ADP
gs-3921	173	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	173	12	testing	testing	NOUN
gs-3921	173	13	,	,	PUNCT
gs-3921	173	14	often	often	ADV
gs-3921	173	15	constrained	constrain	VERB
gs-3921	173	16	by	by	ADP
gs-3921	173	17	cost	cost	NOUN
gs-3921	173	18	,	,	PUNCT
gs-3921	173	19	lack	lack	NOUN
gs-3921	173	20	of	of	ADP
gs-3921	173	21	reimbursement	reimbursement	NOUN
gs-3921	173	22	,	,	PUNCT
gs-3921	173	23	and	and	CCONJ
gs-3921	173	24	insufficient	insufficient	ADJ
gs-3921	173	25	clinician	clinician	ADJ
gs-3921	173	26	familiarity	familiarity	NOUN
gs-3921	173	27	with	with	ADP
gs-3921	173	28	genetic	genetic	ADJ
gs-3921	173	29	data	data	NOUN
gs-3921	173	30	interpretation	interpretation	NOUN
gs-3921	173	31	.	.	PUNCT
gs-3921	174	1	many	many	ADJ
gs-3921	174	2	healthcare	healthcare	NOUN
gs-3921	174	3	providers	provider	NOUN
gs-3921	174	4	report	report	VERB
gs-3921	174	5	uncertainty	uncertainty	NOUN
gs-3921	174	6	about	about	ADP
gs-3921	174	7	how	how	SCONJ
gs-3921	174	8	to	to	PART
gs-3921	174	9	integrate	integrate	VERB
gs-3921	174	10	test	test	NOUN
gs-3921	174	11	results	result	NOUN
gs-3921	174	12	into	into	ADP
gs-3921	174	13	prescribing	prescribing	NOUN
gs-3921	174	14	decisions	decision	NOUN
gs-3921	174	15	,	,	PUNCT
gs-3921	174	16	underscoring	underscore	VERB
gs-3921	174	17	the	the	DET
gs-3921	174	18	need	need	NOUN
gs-3921	174	19	for	for	ADP
gs-3921	174	20	enhanced	enhanced	ADJ
gs-3921	174	21	education	education	NOUN
gs-3921	174	22	and	and	CCONJ
gs-3921	174	23	clinical	clinical	ADJ
gs-3921	174	24	decision	decision	NOUN
gs-3921	174	25	support	support	NOUN
gs-3921	174	26	tools	tool	NOUN
gs-3921	174	27	.	.	PUNCT
gs-3921	175	1	additionally	additionally	ADV
gs-3921	175	2	,	,	PUNCT
gs-3921	175	3	patient	patient	ADJ
gs-3921	175	4	acceptance	acceptance	NOUN
gs-3921	175	5	of	of	ADP
gs-3921	175	6	genetic	genetic	ADJ
gs-3921	175	7	testing	testing	NOUN
gs-3921	175	8	varies	varie	NOUN
gs-3921	175	9	,	,	PUNCT
gs-3921	175	10	influenced	influence	VERB
gs-3921	175	11	by	by	ADP
gs-3921	175	12	factors	factor	NOUN
gs-3921	175	13	such	such	ADJ
gs-3921	175	14	as	as	ADP
gs-3921	175	15	health	health	NOUN
gs-3921	175	16	literacy	literacy	NOUN
gs-3921	175	17	,	,	PUNCT
gs-3921	175	18	cultural	cultural	ADJ
gs-3921	175	19	beliefs	belief	NOUN
gs-3921	175	20	,	,	PUNCT
gs-3921	175	21	and	and	CCONJ
gs-3921	175	22	concerns	concern	NOUN
gs-3921	175	23	regarding	regard	VERB
gs-3921	175	24	data	data	NOUN
gs-3921	175	25	privacy	privacy	NOUN
gs-3921	175	26	.	.	PUNCT
gs-3921	176	1	these	these	DET
gs-3921	176	2	findings	finding	NOUN
gs-3921	176	3	highlight	highlight	VERB
gs-3921	176	4	that	that	SCONJ
gs-3921	176	5	the	the	DET
gs-3921	176	6	mere	mere	ADJ
gs-3921	176	7	presence	presence	NOUN
gs-3921	176	8	of	of	ADP
gs-3921	176	9	robust	robust	ADJ
gs-3921	176	10	scientific	scientific	ADJ
gs-3921	176	11	evidence	evidence	NOUN
gs-3921	176	12	is	be	AUX
gs-3921	176	13	insufficient	insufficient	ADJ
gs-3921	176	14	to	to	PART
gs-3921	176	15	ensure	ensure	VERB
gs-3921	176	16	clinical	clinical	ADJ
gs-3921	176	17	impact	impact	NOUN
gs-3921	176	18	without	without	ADP
gs-3921	176	19	addressing	address	VERB
gs-3921	176	20	systemic	systemic	ADJ
gs-3921	176	21	,	,	PUNCT
gs-3921	176	22	educational	educational	ADJ
gs-3921	176	23	,	,	PUNCT
gs-3921	176	24	and	and	CCONJ
gs-3921	176	25	psychosocial	psychosocial	ADJ
gs-3921	176	26	factors	factor	NOUN
gs-3921	176	27	.	.	PUNCT
gs-3921	177	1	the	the	DET
gs-3921	177	2	patient	patient	NOUN
gs-3921	177	3	-	-	PUNCT
gs-3921	177	4	centered	center	VERB
gs-3921	177	5	care	care	NOUN
gs-3921	177	6	paradigm	paradigm	NOUN
gs-3921	177	7	emerges	emerge	VERB
gs-3921	177	8	as	as	ADP
gs-3921	177	9	a	a	DET
gs-3921	177	10	critical	critical	ADJ
gs-3921	177	11	enabler	enabler	NOUN
gs-3921	177	12	for	for	ADP
gs-3921	177	13	the	the	DET
gs-3921	177	14	successful	successful	ADJ
gs-3921	177	15	incorporation	incorporation	NOUN
gs-3921	177	16	of	of	ADP
gs-3921	177	17	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	177	18	into	into	ADP
gs-3921	177	19	therapeutic	therapeutic	ADJ
gs-3921	177	20	decision	decision	NOUN
gs-3921	177	21	-	-	PUNCT
gs-3921	177	22	making	making	NOUN
gs-3921	177	23	.	.	PUNCT
gs-3921	178	1	engaging	engage	VERB
gs-3921	178	2	patients	patient	NOUN
gs-3921	178	3	through	through	ADP
gs-3921	178	4	shared	share	VERB
gs-3921	178	5	decision	decision	NOUN
gs-3921	178	6	-	-	PUNCT
gs-3921	178	7	making	make	VERB
gs-3921	178	8	fosters	foster	NOUN
gs-3921	178	9	understanding	understanding	NOUN
gs-3921	178	10	and	and	CCONJ
gs-3921	178	11	trust	trust	NOUN
gs-3921	178	12	,	,	PUNCT
gs-3921	178	13	which	which	PRON
gs-3921	178	14	in	in	ADP
gs-3921	178	15	turn	turn	NOUN
gs-3921	178	16	enhances	enhance	VERB
gs-3921	178	17	adherence	adherence	NOUN
gs-3921	178	18	to	to	ADP
gs-3921	178	19	prescribed	prescribe	VERB
gs-3921	178	20	regimens	regimen	NOUN
gs-3921	178	21	and	and	CCONJ
gs-3921	178	22	openness	openness	NOUN
gs-3921	178	23	to	to	ADP
gs-3921	178	24	genetic	genetic	ADJ
gs-3921	178	25	testing	testing	NOUN
gs-3921	178	26	.	.	PUNCT
gs-3921	179	1	studies	study	NOUN
gs-3921	179	2	indicate	indicate	VERB
gs-3921	179	3	that	that	SCONJ
gs-3921	179	4	when	when	SCONJ
gs-3921	179	5	patients	patient	NOUN
gs-3921	179	6	are	be	AUX
gs-3921	179	7	actively	actively	ADV
gs-3921	179	8	involved	involve	VERB
gs-3921	179	9	in	in	ADP
gs-3921	179	10	discussions	discussion	NOUN
gs-3921	179	11	about	about	ADP
gs-3921	179	12	medication	medication	NOUN
gs-3921	179	13	risks	risk	NOUN
gs-3921	179	14	and	and	CCONJ
gs-3921	179	15	benefits	benefit	NOUN
gs-3921	179	16	,	,	PUNCT
gs-3921	179	17	including	include	VERB
gs-3921	179	18	the	the	DET
gs-3921	179	19	implications	implication	NOUN
gs-3921	179	20	of	of	ADP
gs-3921	179	21	their	their	PRON
gs-3921	179	22	genetic	genetic	ADJ
gs-3921	179	23	profile	profile	NOUN
gs-3921	179	24	,	,	PUNCT
gs-3921	179	25	there	there	PRON
gs-3921	179	26	is	be	VERB
gs-3921	179	27	greater	great	ADJ
gs-3921	179	28	satisfaction	satisfaction	NOUN
gs-3921	179	29	and	and	CCONJ
gs-3921	179	30	georgian	georgian	ADJ
gs-3921	179	31	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	179	32	მეცნიერები	მეცნიერები	NOUN
gs-3921	179	33	ტ.	ტ.	VERB
gs-3921	179	34	7	7	NUM
gs-3921	179	35	n	n	PRON
gs-3921	179	36	3	3	NUM
gs-3921	179	37	,	,	PUNCT
gs-3921	179	38	2025	2025	NUM
gs-3921	179	39	229	229	NUM
gs-3921	179	40	empowerment	empowerment	NOUN
gs-3921	179	41	.	.	PUNCT
gs-3921	180	1	however	however	ADV
gs-3921	180	2	,	,	PUNCT
gs-3921	180	3	effective	effective	ADJ
gs-3921	180	4	communication	communication	NOUN
gs-3921	180	5	requires	require	VERB
gs-3921	180	6	that	that	SCONJ
gs-3921	180	7	healthcare	healthcare	NOUN
gs-3921	180	8	providers	provider	NOUN
gs-3921	180	9	possess	possess	VERB
gs-3921	180	10	not	not	PART
gs-3921	180	11	only	only	ADV
gs-3921	180	12	technical	technical	ADJ
gs-3921	180	13	knowledge	knowledge	NOUN
gs-3921	180	14	but	but	CCONJ
gs-3921	180	15	also	also	ADV
gs-3921	180	16	the	the	DET
gs-3921	180	17	skills	skill	NOUN
gs-3921	180	18	to	to	PART
gs-3921	180	19	translate	translate	VERB
gs-3921	180	20	complex	complex	ADJ
gs-3921	180	21	genetic	genetic	ADJ
gs-3921	180	22	concepts	concept	NOUN
gs-3921	180	23	into	into	ADP
gs-3921	180	24	accessible	accessible	ADJ
gs-3921	180	25	language	language	NOUN
gs-3921	180	26	tailored	tailor	VERB
gs-3921	180	27	to	to	ADP
gs-3921	180	28	individual	individual	ADJ
gs-3921	180	29	patient	patient	NOUN
gs-3921	180	30	needs	need	NOUN
gs-3921	180	31	.	.	PUNCT
gs-3921	181	1	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	181	2	systems	system	NOUN
gs-3921	181	3	face	face	VERB
gs-3921	181	4	ongoing	ongoing	ADJ
gs-3921	181	5	challenges	challenge	NOUN
gs-3921	181	6	in	in	ADP
gs-3921	181	7	capturing	capture	VERB
gs-3921	181	8	and	and	CCONJ
gs-3921	181	9	responding	respond	VERB
gs-3921	181	10	to	to	ADP
gs-3921	181	11	medication	medication	NOUN
gs-3921	181	12	-	-	PUNCT
gs-3921	181	13	induced	induce	VERB
gs-3921	181	14	adverse	adverse	ADJ
gs-3921	181	15	effects	effect	NOUN
gs-3921	181	16	in	in	ADP
gs-3921	181	17	a	a	DET
gs-3921	181	18	timely	timely	ADJ
gs-3921	181	19	and	and	CCONJ
gs-3921	181	20	comprehensive	comprehensive	ADJ
gs-3921	181	21	manner	manner	NOUN
gs-3921	181	22	.	.	PUNCT
gs-3921	182	1	traditional	traditional	ADJ
gs-3921	182	2	spontaneous	spontaneous	ADJ
gs-3921	182	3	reporting	reporting	NOUN
gs-3921	182	4	mechanisms	mechanism	NOUN
gs-3921	182	5	suffer	suffer	VERB
gs-3921	182	6	from	from	ADP
gs-3921	182	7	underreporting	underreporte	VERB
gs-3921	182	8	and	and	CCONJ
gs-3921	182	9	delayed	delay	VERB
gs-3921	182	10	recognition	recognition	NOUN
gs-3921	182	11	of	of	ADP
gs-3921	182	12	safety	safety	NOUN
gs-3921	182	13	signals	signal	NOUN
gs-3921	182	14	,	,	PUNCT
gs-3921	182	15	particularly	particularly	ADV
gs-3921	182	16	for	for	ADP
gs-3921	182	17	rare	rare	ADJ
gs-3921	182	18	or	or	CCONJ
gs-3921	182	19	idiosyncratic	idiosyncratic	ADJ
gs-3921	182	20	reactions	reaction	NOUN
gs-3921	182	21	.	.	PUNCT
gs-3921	183	1	integration	integration	NOUN
gs-3921	183	2	of	of	ADP
gs-3921	183	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	183	4	data	datum	NOUN
gs-3921	183	5	into	into	ADP
gs-3921	183	6	these	these	DET
gs-3921	183	7	systems	system	NOUN
gs-3921	183	8	enhances	enhance	VERB
gs-3921	183	9	the	the	DET
gs-3921	183	10	detection	detection	NOUN
gs-3921	183	11	and	and	CCONJ
gs-3921	183	12	characterization	characterization	NOUN
gs-3921	183	13	of	of	ADP
gs-3921	183	14	gene	gene	NOUN
gs-3921	183	15	-	-	PUNCT
gs-3921	183	16	related	relate	VERB
gs-3921	183	17	adverse	adverse	ADJ
gs-3921	183	18	events	event	NOUN
gs-3921	183	19	,	,	PUNCT
gs-3921	183	20	enabling	enable	VERB
gs-3921	183	21	more	more	ADJ
gs-3921	183	22	targeted	target	VERB
gs-3921	183	23	risk	risk	NOUN
gs-3921	183	24	mitigation	mitigation	NOUN
gs-3921	183	25	.	.	PUNCT
gs-3921	184	1	active	active	ADJ
gs-3921	184	2	surveillance	surveillance	NOUN
gs-3921	184	3	strategies	strategy	NOUN
gs-3921	184	4	leveraging	leverage	VERB
gs-3921	184	5	electronic	electronic	ADJ
gs-3921	184	6	health	health	NOUN
gs-3921	184	7	records	record	NOUN
gs-3921	184	8	,	,	PUNCT
gs-3921	184	9	patient	patient	ADJ
gs-3921	184	10	registries	registry	NOUN
gs-3921	184	11	,	,	PUNCT
gs-3921	184	12	and	and	CCONJ
gs-3921	184	13	digital	digital	ADJ
gs-3921	184	14	health	health	NOUN
gs-3921	184	15	tools	tool	NOUN
gs-3921	184	16	have	have	AUX
gs-3921	184	17	shown	show	VERB
gs-3921	184	18	promise	promise	NOUN
gs-3921	184	19	in	in	ADP
gs-3921	184	20	improving	improve	VERB
gs-3921	184	21	the	the	DET
gs-3921	184	22	scope	scope	NOUN
gs-3921	184	23	and	and	CCONJ
gs-3921	184	24	sensitivity	sensitivity	NOUN
gs-3921	184	25	of	of	ADP
gs-3921	184	26	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	184	27	activities	activity	NOUN
gs-3921	184	28	.	.	PUNCT
gs-3921	185	1	however	however	ADV
gs-3921	185	2	,	,	PUNCT
gs-3921	185	3	such	such	ADJ
gs-3921	185	4	approaches	approach	NOUN
gs-3921	185	5	require	require	VERB
gs-3921	185	6	substantial	substantial	ADJ
gs-3921	185	7	investment	investment	NOUN
gs-3921	185	8	in	in	ADP
gs-3921	185	9	data	datum	NOUN
gs-3921	185	10	infrastructure	infrastructure	NOUN
gs-3921	185	11	,	,	PUNCT
gs-3921	185	12	interoperability	interoperability	NOUN
gs-3921	185	13	standards	standard	NOUN
gs-3921	185	14	,	,	PUNCT
gs-3921	185	15	and	and	CCONJ
gs-3921	185	16	analytic	analytic	ADJ
gs-3921	185	17	capabilities	capability	NOUN
gs-3921	185	18	.	.	PUNCT
gs-3921	186	1	the	the	DET
gs-3921	186	2	management	management	NOUN
gs-3921	186	3	of	of	ADP
gs-3921	186	4	medication	medication	NOUN
gs-3921	186	5	-	-	PUNCT
gs-3921	186	6	induced	induce	VERB
gs-3921	186	7	toxicities	toxicity	NOUN
gs-3921	186	8	through	through	ADP
gs-3921	186	9	pharmacogenetic	pharmacogenetic	ADV
gs-3921	186	10	-	-	PUNCT
gs-3921	186	11	informed	inform	VERB
gs-3921	186	12	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	186	13	is	be	AUX
gs-3921	186	14	gaining	gain	VERB
gs-3921	186	15	traction	traction	NOUN
gs-3921	186	16	as	as	ADP
gs-3921	186	17	a	a	DET
gs-3921	186	18	feasible	feasible	ADJ
gs-3921	186	19	and	and	CCONJ
gs-3921	186	20	beneficial	beneficial	ADJ
gs-3921	186	21	approach	approach	NOUN
gs-3921	186	22	.	.	PUNCT
gs-3921	187	1	personalized	personalize	VERB
gs-3921	187	2	dosing	dose	VERB
gs-3921	187	3	algorithms	algorithm	NOUN
gs-3921	187	4	,	,	PUNCT
gs-3921	187	5	alternative	alternative	ADJ
gs-3921	187	6	drug	drug	NOUN
gs-3921	187	7	selection	selection	NOUN
gs-3921	187	8	based	base	VERB
gs-3921	187	9	on	on	ADP
gs-3921	187	10	genetic	genetic	ADJ
gs-3921	187	11	risk	risk	NOUN
gs-3921	187	12	profiles	profile	NOUN
gs-3921	187	13	,	,	PUNCT
gs-3921	187	14	and	and	CCONJ
gs-3921	187	15	preemptive	preemptive	ADJ
gs-3921	187	16	screening	screening	NOUN
gs-3921	187	17	programs	program	NOUN
gs-3921	187	18	contribute	contribute	VERB
gs-3921	187	19	to	to	ADP
gs-3921	187	20	reducing	reduce	VERB
gs-3921	187	21	adverse	adverse	ADJ
gs-3921	187	22	events	event	NOUN
gs-3921	187	23	and	and	CCONJ
gs-3921	187	24	optimizing	optimize	VERB
gs-3921	187	25	efficacy	efficacy	NOUN
gs-3921	187	26	.	.	PUNCT
gs-3921	188	1	nevertheless	nevertheless	ADV
gs-3921	188	2	,	,	PUNCT
gs-3921	188	3	clinical	clinical	ADJ
gs-3921	188	4	guidelines	guideline	NOUN
gs-3921	188	5	often	often	ADV
gs-3921	188	6	lag	lag	VERB
gs-3921	188	7	behind	behind	ADP
gs-3921	188	8	emerging	emerge	VERB
gs-3921	188	9	evidence	evidence	NOUN
gs-3921	188	10	,	,	PUNCT
gs-3921	188	11	and	and	CCONJ
gs-3921	188	12	variability	variability	NOUN
gs-3921	188	13	exists	exist	VERB
gs-3921	188	14	in	in	ADP
gs-3921	188	15	the	the	DET
gs-3921	188	16	recommendations	recommendation	NOUN
gs-3921	188	17	provided	provide	VERB
gs-3921	188	18	by	by	ADP
gs-3921	188	19	different	different	ADJ
gs-3921	188	20	regulatory	regulatory	ADJ
gs-3921	188	21	bodies	body	NOUN
gs-3921	188	22	and	and	CCONJ
gs-3921	188	23	professional	professional	ADJ
gs-3921	188	24	organizations	organization	NOUN
gs-3921	188	25	.	.	PUNCT
gs-3921	189	1	this	this	DET
gs-3921	189	2	inconsistency	inconsistency	NOUN
gs-3921	189	3	can	can	AUX
gs-3921	189	4	create	create	VERB
gs-3921	189	5	confusion	confusion	NOUN
gs-3921	189	6	for	for	ADP
gs-3921	189	7	clinicians	clinician	NOUN
gs-3921	189	8	and	and	CCONJ
gs-3921	189	9	impede	impede	VERB
gs-3921	189	10	harmonized	harmonized	ADJ
gs-3921	189	11	adoption	adoption	NOUN
gs-3921	189	12	.	.	PUNCT
gs-3921	190	1	the	the	DET
gs-3921	190	2	establishment	establishment	NOUN
gs-3921	190	3	of	of	ADP
gs-3921	190	4	centralized	centralized	ADJ
gs-3921	190	5	,	,	PUNCT
gs-3921	190	6	evidence	evidence	NOUN
gs-3921	190	7	-	-	PUNCT
gs-3921	190	8	based	base	VERB
gs-3921	190	9	,	,	PUNCT
gs-3921	190	10	and	and	CCONJ
gs-3921	190	11	regularly	regularly	ADV
gs-3921	190	12	updated	update	VERB
gs-3921	190	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	190	14	guidelines	guideline	NOUN
gs-3921	190	15	,	,	PUNCT
gs-3921	190	16	integrated	integrate	VERB
gs-3921	190	17	within	within	ADP
gs-3921	190	18	clinical	clinical	ADJ
gs-3921	190	19	decision	decision	NOUN
gs-3921	190	20	support	support	NOUN
gs-3921	190	21	systems	system	NOUN
gs-3921	190	22	,	,	PUNCT
gs-3921	190	23	is	be	AUX
gs-3921	190	24	essential	essential	ADJ
gs-3921	190	25	to	to	PART
gs-3921	190	26	bridge	bridge	VERB
gs-3921	190	27	this	this	DET
gs-3921	190	28	gap	gap	NOUN
gs-3921	190	29	.	.	PUNCT
gs-3921	191	1	ethical	ethical	ADJ
gs-3921	191	2	,	,	PUNCT
gs-3921	191	3	legal	legal	ADJ
gs-3921	191	4	,	,	PUNCT
gs-3921	191	5	and	and	CCONJ
gs-3921	191	6	social	social	ADJ
gs-3921	191	7	considerations	consideration	NOUN
gs-3921	191	8	are	be	AUX
gs-3921	191	9	intricately	intricately	ADV
gs-3921	191	10	woven	weave	VERB
gs-3921	191	11	throughout	throughout	ADP
gs-3921	191	12	the	the	DET
gs-3921	191	13	process	process	NOUN
gs-3921	191	14	of	of	ADP
gs-3921	191	15	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	191	16	integration	integration	NOUN
gs-3921	191	17	and	and	CCONJ
gs-3921	191	18	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	191	19	enhancement	enhancement	NOUN
gs-3921	191	20	.	.	PUNCT
gs-3921	192	1	concerns	concern	NOUN
gs-3921	192	2	about	about	ADP
gs-3921	192	3	genetic	genetic	ADJ
gs-3921	192	4	data	datum	NOUN
gs-3921	192	5	security	security	NOUN
gs-3921	192	6	,	,	PUNCT
gs-3921	192	7	potential	potential	ADJ
gs-3921	192	8	discrimination	discrimination	NOUN
gs-3921	192	9	,	,	PUNCT
gs-3921	192	10	and	and	CCONJ
gs-3921	192	11	equitable	equitable	ADJ
gs-3921	192	12	access	access	NOUN
gs-3921	192	13	to	to	ADP
gs-3921	192	14	testing	testing	NOUN
gs-3921	192	15	must	must	AUX
gs-3921	192	16	be	be	AUX
gs-3921	192	17	proactively	proactively	ADV
gs-3921	192	18	addressed	address	VERB
gs-3921	192	19	through	through	ADP
gs-3921	192	20	policy	policy	NOUN
gs-3921	192	21	and	and	CCONJ
gs-3921	192	22	practice	practice	NOUN
gs-3921	192	23	.	.	PUNCT
gs-3921	193	1	studies	study	NOUN
gs-3921	193	2	emphasize	emphasize	VERB
gs-3921	193	3	the	the	DET
gs-3921	193	4	importance	importance	NOUN
gs-3921	193	5	of	of	ADP
gs-3921	193	6	transparent	transparent	ADJ
gs-3921	193	7	informed	informed	ADJ
gs-3921	193	8	consent	consent	NOUN
gs-3921	193	9	processes	process	NOUN
gs-3921	193	10	,	,	PUNCT
gs-3921	193	11	culturally	culturally	ADV
gs-3921	193	12	sensitive	sensitive	ADJ
gs-3921	193	13	patient	patient	ADJ
gs-3921	193	14	engagement	engagement	NOUN
gs-3921	193	15	,	,	PUNCT
gs-3921	193	16	and	and	CCONJ
gs-3921	193	17	policies	policy	NOUN
gs-3921	193	18	that	that	PRON
gs-3921	193	19	protect	protect	VERB
gs-3921	193	20	against	against	ADP
gs-3921	193	21	misuse	misuse	NOUN
gs-3921	193	22	of	of	ADP
gs-3921	193	23	genetic	genetic	ADJ
gs-3921	193	24	information	information	NOUN
gs-3921	193	25	.	.	PUNCT
gs-3921	194	1	equitable	equitable	ADJ
gs-3921	194	2	implementation	implementation	NOUN
gs-3921	194	3	strategies	strategy	NOUN
gs-3921	194	4	are	be	AUX
gs-3921	194	5	critical	critical	ADJ
gs-3921	194	6	to	to	PART
gs-3921	194	7	ensure	ensure	VERB
gs-3921	194	8	that	that	SCONJ
gs-3921	194	9	advances	advance	NOUN
gs-3921	194	10	in	in	ADP
gs-3921	194	11	personalized	personalized	ADJ
gs-3921	194	12	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	194	13	benefit	benefit	VERB
gs-3921	194	14	diverse	diverse	ADJ
gs-3921	194	15	populations	population	NOUN
gs-3921	194	16	and	and	CCONJ
gs-3921	194	17	do	do	AUX
gs-3921	194	18	not	not	PART
gs-3921	194	19	exacerbate	exacerbate	VERB
gs-3921	194	20	existing	exist	VERB
gs-3921	194	21	health	health	NOUN
gs-3921	194	22	disparities	disparity	NOUN
gs-3921	194	23	.	.	PUNCT
gs-3921	195	1	technological	technological	ADJ
gs-3921	195	2	innovations	innovation	NOUN
gs-3921	195	3	underpin	underpin	VERB
gs-3921	195	4	much	much	ADJ
gs-3921	195	5	of	of	ADP
gs-3921	195	6	the	the	DET
gs-3921	195	7	progress	progress	NOUN
gs-3921	195	8	and	and	CCONJ
gs-3921	195	9	future	future	ADJ
gs-3921	195	10	potential	potential	NOUN
gs-3921	195	11	in	in	ADP
gs-3921	195	12	this	this	DET
gs-3921	195	13	field	field	NOUN
gs-3921	195	14	.	.	PUNCT
gs-3921	196	1	the	the	DET
gs-3921	196	2	deployment	deployment	NOUN
gs-3921	196	3	of	of	ADP
gs-3921	196	4	artificial	artificial	ADJ
gs-3921	196	5	intelligence	intelligence	NOUN
gs-3921	196	6	and	and	CCONJ
gs-3921	196	7	machine	machine	NOUN
gs-3921	196	8	learning	learn	VERB
gs-3921	196	9	for	for	ADP
gs-3921	196	10	predictive	predictive	ADJ
gs-3921	196	11	modeling	modeling	NOUN
gs-3921	196	12	of	of	ADP
gs-3921	196	13	adverse	adverse	ADJ
gs-3921	196	14	drug	drug	NOUN
gs-3921	196	15	reactions	reaction	NOUN
gs-3921	196	16	offers	offer	VERB
gs-3921	196	17	unprecedented	unprecedented	ADJ
gs-3921	196	18	opportunities	opportunity	NOUN
gs-3921	196	19	to	to	PART
gs-3921	196	20	personalize	personalize	VERB
gs-3921	196	21	risk	risk	NOUN
gs-3921	196	22	assessment	assessment	NOUN
gs-3921	196	23	.	.	PUNCT
gs-3921	197	1	wearable	wearable	ADJ
gs-3921	197	2	health	health	NOUN
gs-3921	197	3	technologies	technology	NOUN
gs-3921	197	4	and	and	CCONJ
gs-3921	197	5	mobile	mobile	ADJ
gs-3921	197	6	applications	application	NOUN
gs-3921	197	7	facilitate	facilitate	VERB
gs-3921	197	8	real	real	ADJ
gs-3921	197	9	-	-	PUNCT
gs-3921	197	10	time	time	NOUN
gs-3921	197	11	monitoring	monitoring	NOUN
gs-3921	197	12	of	of	ADP
gs-3921	197	13	patients	patient	NOUN
gs-3921	197	14	,	,	PUNCT
gs-3921	197	15	enabling	enable	VERB
gs-3921	197	16	early	early	ADJ
gs-3921	197	17	detection	detection	NOUN
gs-3921	197	18	of	of	ADP
gs-3921	197	19	adverse	adverse	ADJ
gs-3921	197	20	effects	effect	NOUN
gs-3921	197	21	and	and	CCONJ
gs-3921	197	22	timely	timely	ADJ
gs-3921	197	23	clinical	clinical	ADJ
gs-3921	197	24	interventions	intervention	NOUN
gs-3921	197	25	.	.	PUNCT
gs-3921	198	1	blockchain	blockchain	NOUN
gs-3921	198	2	-	-	PUNCT
gs-3921	198	3	based	base	VERB
gs-3921	198	4	data	data	NOUN
gs-3921	198	5	management	management	NOUN
gs-3921	198	6	systems	system	NOUN
gs-3921	198	7	hold	hold	VERB
gs-3921	198	8	promise	promise	NOUN
gs-3921	198	9	for	for	ADP
gs-3921	198	10	enhancing	enhance	VERB
gs-3921	198	11	security	security	NOUN
gs-3921	198	12	and	and	CCONJ
gs-3921	198	13	patient	patient	ADJ
gs-3921	198	14	control	control	NOUN
gs-3921	198	15	over	over	ADP
gs-3921	198	16	genetic	genetic	ADJ
gs-3921	198	17	information	information	NOUN
gs-3921	198	18	.	.	PUNCT
gs-3921	199	1	however	however	ADV
gs-3921	199	2	,	,	PUNCT
gs-3921	199	3	the	the	DET
gs-3921	199	4	integration	integration	NOUN
gs-3921	199	5	of	of	ADP
gs-3921	199	6	these	these	DET
gs-3921	199	7	technologies	technology	NOUN
gs-3921	199	8	must	must	AUX
gs-3921	199	9	be	be	AUX
gs-3921	199	10	carefully	carefully	ADV
gs-3921	199	11	managed	manage	VERB
gs-3921	199	12	to	to	PART
gs-3921	199	13	ensure	ensure	VERB
gs-3921	199	14	validity	validity	NOUN
gs-3921	199	15	,	,	PUNCT
gs-3921	199	16	transparency	transparency	NOUN
gs-3921	199	17	,	,	PUNCT
gs-3921	199	18	patient	patient	NOUN
gs-3921	199	19	privacy	privacy	NOUN
gs-3921	199	20	,	,	PUNCT
gs-3921	199	21	and	and	CCONJ
gs-3921	199	22	equitable	equitable	ADJ
gs-3921	199	23	access	access	NOUN
gs-3921	199	24	.	.	PUNCT
gs-3921	200	1	georgian	georgian	ADJ
gs-3921	200	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	200	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	200	4	ტ.	ტ.	VERB
gs-3921	200	5	7	7	NUM
gs-3921	200	6	n	n	DET
gs-3921	200	7	3	3	NUM
gs-3921	200	8	,	,	PUNCT
gs-3921	200	9	2025	2025	NUM
gs-3921	200	10	230	230	NUM
gs-3921	200	11	from	from	ADP
gs-3921	200	12	a	a	DET
gs-3921	200	13	health	health	NOUN
gs-3921	200	14	systems	system	NOUN
gs-3921	200	15	perspective	perspective	NOUN
gs-3921	200	16	,	,	PUNCT
gs-3921	200	17	the	the	DET
gs-3921	200	18	successful	successful	ADJ
gs-3921	200	19	integration	integration	NOUN
gs-3921	200	20	of	of	ADP
gs-3921	200	21	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	200	22	and	and	CCONJ
gs-3921	200	23	patient	patient	NOUN
gs-3921	200	24	-	-	PUNCT
gs-3921	200	25	centered	center	VERB
gs-3921	200	26	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	200	27	requires	require	VERB
gs-3921	200	28	coordinated	coordinated	ADJ
gs-3921	200	29	efforts	effort	NOUN
gs-3921	200	30	across	across	ADP
gs-3921	200	31	multiple	multiple	ADJ
gs-3921	200	32	stakeholders	stakeholder	NOUN
gs-3921	200	33	,	,	PUNCT
gs-3921	200	34	including	include	VERB
gs-3921	200	35	clinicians	clinician	NOUN
gs-3921	200	36	,	,	PUNCT
gs-3921	200	37	pharmacists	pharmacist	NOUN
gs-3921	200	38	,	,	PUNCT
gs-3921	200	39	genetic	genetic	ADJ
gs-3921	200	40	counselors	counselor	NOUN
gs-3921	200	41	,	,	PUNCT
gs-3921	200	42	researchers	researcher	NOUN
gs-3921	200	43	,	,	PUNCT
gs-3921	200	44	regulators	regulator	NOUN
gs-3921	200	45	,	,	PUNCT
gs-3921	200	46	payers	payer	NOUN
gs-3921	200	47	,	,	PUNCT
gs-3921	200	48	and	and	CCONJ
gs-3921	200	49	patients	patient	NOUN
gs-3921	200	50	themselves	themselves	PRON
gs-3921	200	51	.	.	PUNCT
gs-3921	201	1	interprofessional	interprofessional	ADJ
gs-3921	201	2	collaboration	collaboration	NOUN
gs-3921	201	3	,	,	PUNCT
gs-3921	201	4	continuous	continuous	ADJ
gs-3921	201	5	education	education	NOUN
gs-3921	201	6	,	,	PUNCT
gs-3921	201	7	and	and	CCONJ
gs-3921	201	8	supportive	supportive	ADJ
gs-3921	201	9	infrastructure	infrastructure	NOUN
gs-3921	201	10	are	be	AUX
gs-3921	201	11	necessary	necessary	ADJ
gs-3921	201	12	to	to	PART
gs-3921	201	13	create	create	VERB
gs-3921	201	14	sustainable	sustainable	ADJ
gs-3921	201	15	workflows	workflow	NOUN
gs-3921	201	16	and	and	CCONJ
gs-3921	201	17	clinical	clinical	ADJ
gs-3921	201	18	pathways	pathway	NOUN
gs-3921	201	19	.	.	PUNCT
gs-3921	202	1	moreover	moreover	ADV
gs-3921	202	2	,	,	PUNCT
gs-3921	202	3	health	health	NOUN
gs-3921	202	4	policy	policy	NOUN
gs-3921	202	5	must	must	AUX
gs-3921	202	6	align	align	VERB
gs-3921	202	7	incentives	incentive	NOUN
gs-3921	202	8	and	and	CCONJ
gs-3921	202	9	remove	remove	VERB
gs-3921	202	10	financial	financial	ADJ
gs-3921	202	11	and	and	CCONJ
gs-3921	202	12	regulatory	regulatory	ADJ
gs-3921	202	13	barriers	barrier	NOUN
gs-3921	202	14	to	to	PART
gs-3921	202	15	foster	foster	VERB
gs-3921	202	16	adoption	adoption	NOUN
gs-3921	202	17	.	.	PUNCT
gs-3921	203	1	global	global	ADJ
gs-3921	203	2	cooperation	cooperation	NOUN
gs-3921	203	3	and	and	CCONJ
gs-3921	203	4	knowledge	knowledge	NOUN
gs-3921	203	5	sharing	sharing	NOUN
gs-3921	203	6	are	be	AUX
gs-3921	203	7	vital	vital	ADJ
gs-3921	203	8	to	to	PART
gs-3921	203	9	disseminate	disseminate	VERB
gs-3921	203	10	best	good	ADJ
gs-3921	203	11	practices	practice	NOUN
gs-3921	203	12	and	and	CCONJ
gs-3921	203	13	ensure	ensure	VERB
gs-3921	203	14	that	that	SCONJ
gs-3921	203	15	innovations	innovation	NOUN
gs-3921	203	16	reach	reach	VERB
gs-3921	203	17	diverse	diverse	ADJ
gs-3921	203	18	populations	population	NOUN
gs-3921	203	19	worldwide	worldwide	ADV
gs-3921	203	20	.	.	PUNCT
gs-3921	204	1	the	the	DET
gs-3921	204	2	findings	finding	NOUN
gs-3921	204	3	of	of	ADP
gs-3921	204	4	this	this	DET
gs-3921	204	5	comprehensive	comprehensive	ADJ
gs-3921	204	6	analysis	analysis	NOUN
gs-3921	204	7	affirm	affirm	NOUN
gs-3921	204	8	the	the	DET
gs-3921	204	9	transformative	transformative	ADJ
gs-3921	204	10	potential	potential	NOUN
gs-3921	204	11	of	of	ADP
gs-3921	204	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	204	13	and	and	CCONJ
gs-3921	204	14	patient	patient	NOUN
gs-3921	204	15	-	-	PUNCT
gs-3921	204	16	centered	center	VERB
gs-3921	204	17	approaches	approach	NOUN
gs-3921	204	18	in	in	ADP
gs-3921	204	19	reducing	reduce	VERB
gs-3921	204	20	medication	medication	NOUN
gs-3921	204	21	-	-	PUNCT
gs-3921	204	22	induced	induce	VERB
gs-3921	204	23	adverse	adverse	ADJ
gs-3921	204	24	effects	effect	NOUN
gs-3921	204	25	and	and	CCONJ
gs-3921	204	26	optimizing	optimize	VERB
gs-3921	204	27	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	204	28	management	management	NOUN
gs-3921	204	29	.	.	PUNCT
gs-3921	205	1	while	while	SCONJ
gs-3921	205	2	scientific	scientific	ADJ
gs-3921	205	3	evidence	evidence	NOUN
gs-3921	205	4	has	have	AUX
gs-3921	205	5	advanced	advance	VERB
gs-3921	205	6	considerably	considerably	ADV
gs-3921	205	7	,	,	PUNCT
gs-3921	205	8	translation	translation	NOUN
gs-3921	205	9	into	into	ADP
gs-3921	205	10	routine	routine	ADJ
gs-3921	205	11	clinical	clinical	ADJ
gs-3921	205	12	practice	practice	NOUN
gs-3921	205	13	remains	remain	VERB
gs-3921	205	14	incomplete	incomplete	ADJ
gs-3921	205	15	,	,	PUNCT
gs-3921	205	16	impeded	impede	VERB
gs-3921	205	17	by	by	ADP
gs-3921	205	18	educational	educational	ADJ
gs-3921	205	19	,	,	PUNCT
gs-3921	205	20	infrastructural	infrastructural	ADJ
gs-3921	205	21	,	,	PUNCT
gs-3921	205	22	ethical	ethical	ADJ
gs-3921	205	23	,	,	PUNCT
gs-3921	205	24	and	and	CCONJ
gs-3921	205	25	policy	policy	NOUN
gs-3921	205	26	challenges	challenge	NOUN
gs-3921	205	27	.	.	PUNCT
gs-3921	206	1	addressing	address	VERB
gs-3921	206	2	these	these	DET
gs-3921	206	3	multifactorial	multifactorial	ADJ
gs-3921	206	4	barriers	barrier	NOUN
gs-3921	206	5	through	through	ADP
gs-3921	206	6	coordinated	coordinated	ADJ
gs-3921	206	7	strategies	strategy	NOUN
gs-3921	206	8	will	will	AUX
gs-3921	206	9	be	be	AUX
gs-3921	206	10	pivotal	pivotal	ADJ
gs-3921	206	11	in	in	ADP
gs-3921	206	12	realizing	realize	VERB
gs-3921	206	13	the	the	DET
gs-3921	206	14	promise	promise	NOUN
gs-3921	206	15	of	of	ADP
gs-3921	206	16	personalized	personalized	ADJ
gs-3921	206	17	medicine	medicine	NOUN
gs-3921	206	18	and	and	CCONJ
gs-3921	206	19	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	206	20	for	for	ADP
gs-3921	206	21	enhanced	enhanced	ADJ
gs-3921	206	22	patient	patient	ADJ
gs-3921	206	23	safety	safety	NOUN
gs-3921	206	24	and	and	CCONJ
gs-3921	206	25	improved	improve	VERB
gs-3921	206	26	therapeutic	therapeutic	ADJ
gs-3921	206	27	outcomes	outcome	NOUN
gs-3921	206	28	globally	globally	ADV
gs-3921	206	29	.	.	PUNCT
gs-3921	207	1	the	the	DET
gs-3921	207	2	exploration	exploration	NOUN
gs-3921	207	3	of	of	ADP
gs-3921	207	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	207	5	as	as	ADP
gs-3921	207	6	a	a	DET
gs-3921	207	7	transformative	transformative	ADJ
gs-3921	207	8	element	element	NOUN
gs-3921	207	9	in	in	ADP
gs-3921	207	10	personalized	personalized	ADJ
gs-3921	207	11	medicine	medicine	NOUN
gs-3921	207	12	reveals	reveal	VERB
gs-3921	207	13	both	both	PRON
gs-3921	207	14	substantial	substantial	ADJ
gs-3921	207	15	promise	promise	NOUN
gs-3921	207	16	and	and	CCONJ
gs-3921	207	17	ongoing	ongoing	ADJ
gs-3921	207	18	challenges	challenge	NOUN
gs-3921	207	19	in	in	ADP
gs-3921	207	20	clinical	clinical	ADJ
gs-3921	207	21	application	application	NOUN
gs-3921	207	22	.	.	PUNCT
gs-3921	208	1	over	over	ADP
gs-3921	208	2	recent	recent	ADJ
gs-3921	208	3	decades	decade	NOUN
gs-3921	208	4	,	,	PUNCT
gs-3921	208	5	studies	study	NOUN
gs-3921	208	6	have	have	AUX
gs-3921	208	7	consistently	consistently	ADV
gs-3921	208	8	demonstrated	demonstrate	VERB
gs-3921	208	9	that	that	SCONJ
gs-3921	208	10	genetic	genetic	ADJ
gs-3921	208	11	polymorphisms	polymorphism	NOUN
gs-3921	208	12	in	in	ADP
gs-3921	208	13	drug	drug	NOUN
gs-3921	208	14	-	-	PUNCT
gs-3921	208	15	metabolizing	metabolize	VERB
gs-3921	208	16	enzymes	enzyme	NOUN
gs-3921	208	17	,	,	PUNCT
gs-3921	208	18	transporters	transporter	NOUN
gs-3921	208	19	,	,	PUNCT
gs-3921	208	20	and	and	CCONJ
gs-3921	208	21	receptors	receptor	NOUN
gs-3921	208	22	substantially	substantially	ADV
gs-3921	208	23	affect	affect	VERB
gs-3921	208	24	individual	individual	ADJ
gs-3921	208	25	susceptibility	susceptibility	NOUN
gs-3921	208	26	to	to	ADP
gs-3921	208	27	medication	medication	NOUN
gs-3921	208	28	-	-	PUNCT
gs-3921	208	29	induced	induce	VERB
gs-3921	208	30	adverse	adverse	ADJ
gs-3921	208	31	reactions	reaction	NOUN
gs-3921	208	32	.	.	PUNCT
gs-3921	209	1	these	these	DET
gs-3921	209	2	polymorphisms	polymorphism	NOUN
gs-3921	209	3	contribute	contribute	VERB
gs-3921	209	4	to	to	PART
gs-3921	209	5	altered	alter	VERB
gs-3921	209	6	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	209	7	and	and	CCONJ
gs-3921	209	8	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	209	9	,	,	PUNCT
gs-3921	209	10	leading	lead	VERB
gs-3921	209	11	to	to	ADP
gs-3921	209	12	therapeutic	therapeutic	ADJ
gs-3921	209	13	failures	failure	NOUN
gs-3921	209	14	or	or	CCONJ
gs-3921	209	15	toxicities	toxicity	NOUN
gs-3921	209	16	.	.	PUNCT
gs-3921	210	1	cytochrome	cytochrome	NOUN
gs-3921	210	2	p450	p450	NUM
gs-3921	210	3	enzymes	enzyme	NOUN
gs-3921	210	4	,	,	PUNCT
gs-3921	210	5	particularly	particularly	ADV
gs-3921	210	6	cyp2d6	cyp2d6	NOUN
gs-3921	210	7	,	,	PUNCT
gs-3921	210	8	cyp2c19	cyp2c19	NOUN
gs-3921	210	9	,	,	PUNCT
gs-3921	210	10	and	and	CCONJ
gs-3921	210	11	cyp3a4	cyp3a4	NOUN
gs-3921	210	12	,	,	PUNCT
gs-3921	210	13	serve	serve	VERB
gs-3921	210	14	as	as	ADP
gs-3921	210	15	archetypal	archetypal	ADJ
gs-3921	210	16	examples	example	NOUN
gs-3921	210	17	wherein	wherein	SCONJ
gs-3921	210	18	genetic	genetic	ADJ
gs-3921	210	19	variants	variant	NOUN
gs-3921	210	20	result	result	VERB
gs-3921	210	21	in	in	ADP
gs-3921	210	22	poor	poor	ADJ
gs-3921	210	23	,	,	PUNCT
gs-3921	210	24	intermediate	intermediate	ADJ
gs-3921	210	25	,	,	PUNCT
gs-3921	210	26	extensive	extensive	ADJ
gs-3921	210	27	,	,	PUNCT
gs-3921	210	28	or	or	CCONJ
gs-3921	210	29	ultra	ultra	ADJ
gs-3921	210	30	-	-	ADJ
gs-3921	210	31	rapid	rapid	ADJ
gs-3921	210	32	metabolism	metabolism	NOUN
gs-3921	210	33	phenotypes	phenotype	NOUN
gs-3921	210	34	.	.	PUNCT
gs-3921	211	1	such	such	ADJ
gs-3921	211	2	variations	variation	NOUN
gs-3921	211	3	dictate	dictate	VERB
gs-3921	211	4	the	the	DET
gs-3921	211	5	plasma	plasma	NOUN
gs-3921	211	6	concentrations	concentration	NOUN
gs-3921	211	7	of	of	ADP
gs-3921	211	8	many	many	ADJ
gs-3921	211	9	commonly	commonly	ADV
gs-3921	211	10	prescribed	prescribe	VERB
gs-3921	211	11	drugs	drug	NOUN
gs-3921	211	12	,	,	PUNCT
gs-3921	211	13	including	include	VERB
gs-3921	211	14	antidepressants	antidepressant	NOUN
gs-3921	211	15	,	,	PUNCT
gs-3921	211	16	antiepileptics	antiepileptic	NOUN
gs-3921	211	17	,	,	PUNCT
gs-3921	211	18	and	and	CCONJ
gs-3921	211	19	anticoagulants	anticoagulant	NOUN
gs-3921	211	20	.	.	PUNCT
gs-3921	212	1	clinical	clinical	ADJ
gs-3921	212	2	trials	trial	NOUN
gs-3921	212	3	and	and	CCONJ
gs-3921	212	4	real	real	ADJ
gs-3921	212	5	-	-	PUNCT
gs-3921	212	6	world	world	NOUN
gs-3921	212	7	observational	observational	ADJ
gs-3921	212	8	studies	study	NOUN
gs-3921	212	9	reveal	reveal	VERB
gs-3921	212	10	that	that	SCONJ
gs-3921	212	11	genotyping	genotype	VERB
gs-3921	212	12	these	these	DET
gs-3921	212	13	enzymes	enzyme	NOUN
gs-3921	212	14	prior	prior	ADV
gs-3921	212	15	to	to	ADP
gs-3921	212	16	drug	drug	NOUN
gs-3921	212	17	initiation	initiation	NOUN
gs-3921	212	18	can	can	AUX
gs-3921	212	19	significantly	significantly	ADV
gs-3921	212	20	reduce	reduce	VERB
gs-3921	212	21	adverse	adverse	ADJ
gs-3921	212	22	drug	drug	NOUN
gs-3921	212	23	events	event	NOUN
gs-3921	212	24	(	(	PUNCT
gs-3921	212	25	ades	ade	NOUN
gs-3921	212	26	)	)	PUNCT
gs-3921	212	27	by	by	ADP
gs-3921	212	28	enabling	enable	VERB
gs-3921	212	29	individualized	individualized	ADJ
gs-3921	212	30	dose	dose	NOUN
gs-3921	212	31	adjustments	adjustment	NOUN
gs-3921	212	32	.	.	PUNCT
gs-3921	213	1	the	the	DET
gs-3921	213	2	utility	utility	NOUN
gs-3921	213	3	of	of	ADP
gs-3921	213	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	213	5	testing	testing	NOUN
gs-3921	213	6	extends	extend	VERB
gs-3921	213	7	beyond	beyond	ADP
gs-3921	213	8	metabolism	metabolism	NOUN
gs-3921	213	9	-	-	PUNCT
gs-3921	213	10	related	relate	VERB
gs-3921	213	11	genes	gene	NOUN
gs-3921	213	12	.	.	PUNCT
gs-3921	214	1	for	for	ADP
gs-3921	214	2	instance	instance	NOUN
gs-3921	214	3	,	,	PUNCT
gs-3921	214	4	human	human	ADJ
gs-3921	214	5	leukocyte	leukocyte	NOUN
gs-3921	214	6	antigen	antigen	NOUN
gs-3921	214	7	(	(	PUNCT
gs-3921	214	8	hla	hla	NOUN
gs-3921	214	9	)	)	PUNCT
gs-3921	214	10	allele	allele	NOUN
gs-3921	214	11	associations	association	NOUN
gs-3921	214	12	with	with	ADP
gs-3921	214	13	severe	severe	ADJ
gs-3921	214	14	cutaneous	cutaneous	ADJ
gs-3921	214	15	adverse	adverse	ADJ
gs-3921	214	16	reactions	reaction	NOUN
gs-3921	214	17	(	(	PUNCT
gs-3921	214	18	scar	scar	NOUN
gs-3921	214	19	)	)	PUNCT
gs-3921	214	20	,	,	PUNCT
gs-3921	214	21	such	such	ADJ
gs-3921	214	22	as	as	ADP
gs-3921	214	23	stevens	stevens	PROPN
gs-3921	214	24	-	-	PUNCT
gs-3921	214	25	johnson	johnson	PROPN
gs-3921	214	26	syndrome	syndrome	PROPN
gs-3921	214	27	(	(	PUNCT
gs-3921	214	28	sjs	sjs	PROPN
gs-3921	214	29	)	)	PUNCT
gs-3921	214	30	and	and	CCONJ
gs-3921	214	31	toxic	toxic	ADJ
gs-3921	214	32	epidermal	epidermal	ADJ
gs-3921	214	33	necrolysis	necrolysis	NOUN
gs-3921	214	34	(	(	PUNCT
gs-3921	214	35	ten	ten	NUM
gs-3921	214	36	)	)	PUNCT
gs-3921	214	37	,	,	PUNCT
gs-3921	214	38	have	have	AUX
gs-3921	214	39	been	be	AUX
gs-3921	214	40	well	well	ADV
gs-3921	214	41	documented	document	VERB
gs-3921	214	42	.	.	PUNCT
gs-3921	215	1	the	the	DET
gs-3921	215	2	association	association	PROPN
gs-3921	215	3	of	of	ADP
gs-3921	215	4	hla	hla	PROPN
gs-3921	215	5	-	-	PUNCT
gs-3921	215	6	b15:02	b15:02	PROPN
gs-3921	215	7	with	with	ADP
gs-3921	215	8	carbamazepine	carbamazepine	NOUN
gs-3921	215	9	-	-	PUNCT
gs-3921	215	10	induced	induce	VERB
gs-3921	215	11	sjs	sjs	NOUN
gs-3921	215	12	in	in	ADP
gs-3921	215	13	asian	asian	ADJ
gs-3921	215	14	populations	population	NOUN
gs-3921	215	15	has	have	AUX
gs-3921	215	16	prompted	prompt	VERB
gs-3921	215	17	implementation	implementation	NOUN
gs-3921	215	18	of	of	ADP
gs-3921	215	19	preemptive	preemptive	ADJ
gs-3921	215	20	screening	screening	NOUN
gs-3921	215	21	guidelines	guideline	NOUN
gs-3921	215	22	in	in	ADP
gs-3921	215	23	certain	certain	ADJ
gs-3921	215	24	regions	region	NOUN
gs-3921	215	25	,	,	PUNCT
gs-3921	215	26	substantially	substantially	ADV
gs-3921	215	27	reducing	reduce	VERB
gs-3921	215	28	incidence	incidence	NOUN
gs-3921	215	29	rates	rate	NOUN
gs-3921	215	30	.	.	PUNCT
gs-3921	216	1	similarly	similarly	ADV
gs-3921	216	2	,	,	PUNCT
gs-3921	216	3	the	the	DET
gs-3921	216	4	presence	presence	NOUN
gs-3921	216	5	of	of	ADP
gs-3921	216	6	hla	hla	PROPN
gs-3921	216	7	-	-	PUNCT
gs-3921	216	8	b57:01	b57:01	PROPN
gs-3921	216	9	strongly	strongly	ADV
gs-3921	216	10	predicts	predict	NOUN
gs-3921	216	11	abacavir	abacavir	VERB
gs-3921	216	12	hypersensitivity	hypersensitivity	NOUN
gs-3921	216	13	,	,	PUNCT
gs-3921	216	14	leading	lead	VERB
gs-3921	216	15	to	to	ADP
gs-3921	216	16	mandatory	mandatory	ADJ
gs-3921	216	17	screening	screening	NOUN
gs-3921	216	18	in	in	ADP
gs-3921	216	19	hiv	hiv	PROPN
gs-3921	216	20	treatment	treatment	NOUN
gs-3921	216	21	protocols	protocol	NOUN
gs-3921	216	22	worldwide	worldwide	ADV
gs-3921	216	23	.	.	PUNCT
gs-3921	217	1	these	these	DET
gs-3921	217	2	examples	example	NOUN
gs-3921	217	3	underscore	underscore	VERB
gs-3921	217	4	how	how	SCONJ
gs-3921	217	5	genetic	genetic	ADJ
gs-3921	217	6	insights	insight	NOUN
gs-3921	217	7	can	can	AUX
gs-3921	217	8	directly	directly	ADV
gs-3921	217	9	influence	influence	VERB
gs-3921	217	10	prescribing	prescribing	NOUN
gs-3921	217	11	behaviors	behavior	NOUN
gs-3921	217	12	,	,	PUNCT
gs-3921	217	13	improving	improve	VERB
gs-3921	217	14	patient	patient	ADJ
gs-3921	217	15	safety	safety	NOUN
gs-3921	217	16	and	and	CCONJ
gs-3921	217	17	care	care	NOUN
gs-3921	217	18	quality	quality	NOUN
gs-3921	217	19	.	.	PUNCT
gs-3921	218	1	georgian	georgian	ADJ
gs-3921	218	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	218	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	218	4	ტ.	ტ.	VERB
gs-3921	218	5	7	7	NUM
gs-3921	218	6	n	n	DET
gs-3921	218	7	3	3	NUM
gs-3921	218	8	,	,	PUNCT
gs-3921	218	9	2025	2025	NUM
gs-3921	218	10	231	231	NUM
gs-3921	218	11	despite	despite	SCONJ
gs-3921	218	12	these	these	DET
gs-3921	218	13	clear	clear	ADJ
gs-3921	218	14	clinical	clinical	ADJ
gs-3921	218	15	benefits	benefit	NOUN
gs-3921	218	16	,	,	PUNCT
gs-3921	218	17	adoption	adoption	NOUN
gs-3921	218	18	remains	remain	VERB
gs-3921	218	19	fragmented	fragmented	ADJ
gs-3921	218	20	due	due	ADP
gs-3921	218	21	to	to	ADP
gs-3921	218	22	a	a	DET
gs-3921	218	23	confluence	confluence	NOUN
gs-3921	218	24	of	of	ADP
gs-3921	218	25	barriers	barrier	NOUN
gs-3921	218	26	.	.	PUNCT
gs-3921	219	1	cost	cost	NOUN
gs-3921	219	2	remains	remain	VERB
gs-3921	219	3	a	a	DET
gs-3921	219	4	significant	significant	ADJ
gs-3921	219	5	factor	factor	NOUN
gs-3921	219	6	;	;	PUNCT
gs-3921	219	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	219	8	testing	testing	NOUN
gs-3921	219	9	may	may	AUX
gs-3921	219	10	impose	impose	VERB
gs-3921	219	11	additional	additional	ADJ
gs-3921	219	12	financial	financial	ADJ
gs-3921	219	13	burdens	burden	NOUN
gs-3921	219	14	on	on	ADP
gs-3921	219	15	healthcare	healthcare	NOUN
gs-3921	219	16	systems	system	NOUN
gs-3921	219	17	and	and	CCONJ
gs-3921	219	18	patients	patient	NOUN
gs-3921	219	19	,	,	PUNCT
gs-3921	219	20	especially	especially	ADV
gs-3921	219	21	where	where	SCONJ
gs-3921	219	22	reimbursement	reimbursement	NOUN
gs-3921	219	23	is	be	AUX
gs-3921	219	24	absent	absent	ADJ
gs-3921	219	25	or	or	CCONJ
gs-3921	219	26	inconsistent	inconsistent	ADJ
gs-3921	219	27	.	.	PUNCT
gs-3921	220	1	in	in	ADP
gs-3921	220	2	lowand	lowand	ADJ
gs-3921	220	3	middle	middle	ADJ
gs-3921	220	4	-	-	PUNCT
gs-3921	220	5	income	income	NOUN
gs-3921	220	6	countries	country	NOUN
gs-3921	220	7	,	,	PUNCT
gs-3921	220	8	limited	limited	ADJ
gs-3921	220	9	laboratory	laboratory	NOUN
gs-3921	220	10	infrastructure	infrastructure	NOUN
gs-3921	220	11	and	and	CCONJ
gs-3921	220	12	resource	resource	NOUN
gs-3921	220	13	constraints	constraint	NOUN
gs-3921	220	14	further	far	ADV
gs-3921	220	15	restrict	restrict	VERB
gs-3921	220	16	access	access	NOUN
gs-3921	220	17	.	.	PUNCT
gs-3921	221	1	moreover	moreover	ADV
gs-3921	221	2	,	,	PUNCT
gs-3921	221	3	a	a	DET
gs-3921	221	4	knowledge	knowledge	NOUN
gs-3921	221	5	gap	gap	NOUN
gs-3921	221	6	persists	persist	VERB
gs-3921	221	7	among	among	ADP
gs-3921	221	8	healthcare	healthcare	NOUN
gs-3921	221	9	providers	provider	NOUN
gs-3921	221	10	,	,	PUNCT
gs-3921	221	11	with	with	ADP
gs-3921	221	12	many	many	ADJ
gs-3921	221	13	lacking	lacking	ADJ
gs-3921	221	14	confidence	confidence	NOUN
gs-3921	221	15	in	in	ADP
gs-3921	221	16	interpreting	interpret	VERB
gs-3921	221	17	test	test	NOUN
gs-3921	221	18	results	result	NOUN
gs-3921	221	19	or	or	CCONJ
gs-3921	221	20	understanding	understand	VERB
gs-3921	221	21	their	their	PRON
gs-3921	221	22	clinical	clinical	ADJ
gs-3921	221	23	implications	implication	NOUN
gs-3921	221	24	.	.	PUNCT
gs-3921	222	1	surveys	survey	NOUN
gs-3921	222	2	indicate	indicate	VERB
gs-3921	222	3	that	that	SCONJ
gs-3921	222	4	even	even	ADV
gs-3921	222	5	among	among	ADP
gs-3921	222	6	specialists	specialist	NOUN
gs-3921	222	7	,	,	PUNCT
gs-3921	222	8	uncertainty	uncertainty	NOUN
gs-3921	222	9	about	about	ADP
gs-3921	222	10	test	test	NOUN
gs-3921	222	11	utility	utility	NOUN
gs-3921	222	12	and	and	CCONJ
gs-3921	222	13	lack	lack	NOUN
gs-3921	222	14	of	of	ADP
gs-3921	222	15	clinical	clinical	ADJ
gs-3921	222	16	guidelines	guideline	NOUN
gs-3921	222	17	hinder	hinder	VERB
gs-3921	222	18	uptake	uptake	ADJ
gs-3921	222	19	.	.	PUNCT
gs-3921	223	1	the	the	DET
gs-3921	223	2	absence	absence	NOUN
gs-3921	223	3	of	of	ADP
gs-3921	223	4	standardized	standardized	ADJ
gs-3921	223	5	,	,	PUNCT
gs-3921	223	6	evidence	evidence	NOUN
gs-3921	223	7	-	-	PUNCT
gs-3921	223	8	based	base	VERB
gs-3921	223	9	protocols	protocol	NOUN
gs-3921	223	10	for	for	ADP
gs-3921	223	11	integrating	integrate	VERB
gs-3921	223	12	genetic	genetic	ADJ
gs-3921	223	13	results	result	NOUN
gs-3921	223	14	into	into	ADP
gs-3921	223	15	therapeutic	therapeutic	ADJ
gs-3921	223	16	decision	decision	NOUN
gs-3921	223	17	-	-	PUNCT
gs-3921	223	18	making	making	NOUN
gs-3921	223	19	contributes	contribute	VERB
gs-3921	223	20	to	to	ADP
gs-3921	223	21	variable	variable	ADJ
gs-3921	223	22	practices	practice	NOUN
gs-3921	223	23	and	and	CCONJ
gs-3921	223	24	inconsistent	inconsistent	ADJ
gs-3921	223	25	patient	patient	ADJ
gs-3921	223	26	outcomes	outcome	NOUN
gs-3921	223	27	.	.	PUNCT
gs-3921	224	1	patient	patient	ADJ
gs-3921	224	2	perspectives	perspective	NOUN
gs-3921	224	3	further	far	ADV
gs-3921	224	4	influence	influence	VERB
gs-3921	224	5	the	the	DET
gs-3921	224	6	implementation	implementation	NOUN
gs-3921	224	7	of	of	ADP
gs-3921	224	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	224	9	testing	testing	NOUN
gs-3921	224	10	.	.	PUNCT
gs-3921	225	1	acceptance	acceptance	NOUN
gs-3921	225	2	rates	rate	NOUN
gs-3921	225	3	vary	vary	VERB
gs-3921	225	4	widely	widely	ADV
gs-3921	225	5	and	and	CCONJ
gs-3921	225	6	are	be	AUX
gs-3921	225	7	affected	affect	VERB
gs-3921	225	8	by	by	ADP
gs-3921	225	9	understanding	understanding	NOUN
gs-3921	225	10	of	of	ADP
gs-3921	225	11	genetic	genetic	ADJ
gs-3921	225	12	concepts	concept	NOUN
gs-3921	225	13	,	,	PUNCT
gs-3921	225	14	cultural	cultural	ADJ
gs-3921	225	15	beliefs	belief	NOUN
gs-3921	225	16	,	,	PUNCT
gs-3921	225	17	perceived	perceive	VERB
gs-3921	225	18	risks	risk	NOUN
gs-3921	225	19	and	and	CCONJ
gs-3921	225	20	benefits	benefit	NOUN
gs-3921	225	21	,	,	PUNCT
gs-3921	225	22	and	and	CCONJ
gs-3921	225	23	concerns	concern	NOUN
gs-3921	225	24	regarding	regard	VERB
gs-3921	225	25	data	data	NOUN
gs-3921	225	26	privacy	privacy	NOUN
gs-3921	225	27	and	and	CCONJ
gs-3921	225	28	discrimination	discrimination	NOUN
gs-3921	225	29	.	.	PUNCT
gs-3921	226	1	studies	study	NOUN
gs-3921	226	2	show	show	VERB
gs-3921	226	3	that	that	SCONJ
gs-3921	226	4	comprehensive	comprehensive	ADJ
gs-3921	226	5	counseling	counseling	NOUN
gs-3921	226	6	and	and	CCONJ
gs-3921	226	7	educational	educational	ADJ
gs-3921	226	8	interventions	intervention	NOUN
gs-3921	226	9	improve	improve	VERB
gs-3921	226	10	patient	patient	ADJ
gs-3921	226	11	knowledge	knowledge	NOUN
gs-3921	226	12	and	and	CCONJ
gs-3921	226	13	willingness	willingness	NOUN
gs-3921	226	14	to	to	PART
gs-3921	226	15	participate	participate	VERB
gs-3921	226	16	in	in	ADP
gs-3921	226	17	testing	testing	NOUN
gs-3921	226	18	.	.	PUNCT
gs-3921	227	1	however	however	ADV
gs-3921	227	2	,	,	PUNCT
gs-3921	227	3	time	time	NOUN
gs-3921	227	4	constraints	constraint	NOUN
gs-3921	227	5	and	and	CCONJ
gs-3921	227	6	limited	limited	ADJ
gs-3921	227	7	access	access	NOUN
gs-3921	227	8	to	to	ADP
gs-3921	227	9	trained	train	VERB
gs-3921	227	10	genetic	genetic	ADJ
gs-3921	227	11	counselors	counselor	NOUN
gs-3921	227	12	in	in	ADP
gs-3921	227	13	many	many	ADJ
gs-3921	227	14	clinical	clinical	ADJ
gs-3921	227	15	settings	setting	NOUN
gs-3921	227	16	impede	impede	VERB
gs-3921	227	17	these	these	DET
gs-3921	227	18	efforts	effort	NOUN
gs-3921	227	19	.	.	PUNCT
gs-3921	228	1	addressing	address	VERB
gs-3921	228	2	these	these	DET
gs-3921	228	3	challenges	challenge	NOUN
gs-3921	228	4	necessitates	necessitate	VERB
gs-3921	228	5	innovative	innovative	ADJ
gs-3921	228	6	models	model	NOUN
gs-3921	228	7	of	of	ADP
gs-3921	228	8	patient	patient	ADJ
gs-3921	228	9	engagement	engagement	NOUN
gs-3921	228	10	,	,	PUNCT
gs-3921	228	11	including	include	VERB
gs-3921	228	12	the	the	DET
gs-3921	228	13	use	use	NOUN
gs-3921	228	14	of	of	ADP
gs-3921	228	15	digital	digital	ADJ
gs-3921	228	16	educational	educational	ADJ
gs-3921	228	17	tools	tool	NOUN
gs-3921	228	18	and	and	CCONJ
gs-3921	228	19	decision	decision	NOUN
gs-3921	228	20	aids	aid	NOUN
gs-3921	228	21	tailored	tailor	VERB
gs-3921	228	22	to	to	PART
gs-3921	228	23	diverse	diverse	VERB
gs-3921	228	24	populations	population	NOUN
gs-3921	228	25	.	.	PUNCT
gs-3921	229	1	the	the	DET
gs-3921	229	2	incorporation	incorporation	NOUN
gs-3921	229	3	of	of	ADP
gs-3921	229	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	229	5	data	datum	NOUN
gs-3921	229	6	into	into	ADP
gs-3921	229	7	electronic	electronic	ADJ
gs-3921	229	8	health	health	NOUN
gs-3921	229	9	records	record	NOUN
gs-3921	229	10	(	(	PUNCT
gs-3921	229	11	ehrs	ehrs	INTJ
gs-3921	229	12	)	)	PUNCT
gs-3921	229	13	and	and	CCONJ
gs-3921	229	14	clinical	clinical	ADJ
gs-3921	229	15	decision	decision	NOUN
gs-3921	229	16	support	support	NOUN
gs-3921	229	17	(	(	PUNCT
gs-3921	229	18	cds	cd	NOUN
gs-3921	229	19	)	)	PUNCT
gs-3921	229	20	systems	system	NOUN
gs-3921	229	21	represents	represent	VERB
gs-3921	229	22	a	a	DET
gs-3921	229	23	pivotal	pivotal	ADJ
gs-3921	229	24	strategy	strategy	NOUN
gs-3921	229	25	for	for	ADP
gs-3921	229	26	overcoming	overcome	VERB
gs-3921	229	27	provider	provider	NOUN
gs-3921	229	28	-	-	PUNCT
gs-3921	229	29	related	relate	VERB
gs-3921	229	30	barriers	barrier	NOUN
gs-3921	229	31	.	.	PUNCT
gs-3921	230	1	automated	automate	VERB
gs-3921	230	2	alerts	alert	NOUN
gs-3921	230	3	,	,	PUNCT
gs-3921	230	4	dosing	dose	VERB
gs-3921	230	5	recommendations	recommendation	NOUN
gs-3921	230	6	,	,	PUNCT
gs-3921	230	7	and	and	CCONJ
gs-3921	230	8	drug	drug	NOUN
gs-3921	230	9	selection	selection	NOUN
gs-3921	230	10	guidance	guidance	NOUN
gs-3921	230	11	based	base	VERB
gs-3921	230	12	on	on	ADP
gs-3921	230	13	genetic	genetic	ADJ
gs-3921	230	14	profiles	profile	NOUN
gs-3921	230	15	can	can	AUX
gs-3921	230	16	assist	assist	VERB
gs-3921	230	17	clinicians	clinician	NOUN
gs-3921	230	18	in	in	ADP
gs-3921	230	19	making	make	VERB
gs-3921	230	20	informed	inform	VERB
gs-3921	230	21	,	,	PUNCT
gs-3921	230	22	timely	timely	ADJ
gs-3921	230	23	decisions	decision	NOUN
gs-3921	230	24	.	.	PUNCT
gs-3921	231	1	successful	successful	ADJ
gs-3921	231	2	integration	integration	NOUN
gs-3921	231	3	requires	require	VERB
gs-3921	231	4	interoperability	interoperability	NOUN
gs-3921	231	5	standards	standard	NOUN
gs-3921	231	6	,	,	PUNCT
gs-3921	231	7	user	user	NOUN
gs-3921	231	8	-	-	PUNCT
gs-3921	231	9	friendly	friendly	ADJ
gs-3921	231	10	interfaces	interface	NOUN
gs-3921	231	11	,	,	PUNCT
gs-3921	231	12	and	and	CCONJ
gs-3921	231	13	continuous	continuous	ADJ
gs-3921	231	14	updating	updating	NOUN
gs-3921	231	15	of	of	ADP
gs-3921	231	16	genetic	genetic	ADJ
gs-3921	231	17	knowledge	knowledge	NOUN
gs-3921	231	18	bases	basis	NOUN
gs-3921	231	19	.	.	PUNCT
gs-3921	232	1	nonetheless	nonetheless	ADV
gs-3921	232	2	,	,	PUNCT
gs-3921	232	3	concerns	concern	NOUN
gs-3921	232	4	about	about	ADP
gs-3921	232	5	alert	alert	ADJ
gs-3921	232	6	fatigue	fatigue	NOUN
gs-3921	232	7	,	,	PUNCT
gs-3921	232	8	data	datum	NOUN
gs-3921	232	9	security	security	NOUN
gs-3921	232	10	,	,	PUNCT
gs-3921	232	11	and	and	CCONJ
gs-3921	232	12	system	system	NOUN
gs-3921	232	13	complexity	complexity	NOUN
gs-3921	232	14	necessitate	necessitate	ADJ
gs-3921	232	15	careful	careful	ADJ
gs-3921	232	16	design	design	NOUN
gs-3921	232	17	and	and	CCONJ
gs-3921	232	18	evaluation	evaluation	NOUN
gs-3921	232	19	of	of	ADP
gs-3921	232	20	these	these	DET
gs-3921	232	21	tools	tool	NOUN
gs-3921	232	22	to	to	PART
gs-3921	232	23	maximize	maximize	VERB
gs-3921	232	24	their	their	PRON
gs-3921	232	25	utility	utility	NOUN
gs-3921	232	26	and	and	CCONJ
gs-3921	232	27	acceptance	acceptance	NOUN
gs-3921	232	28	.	.	PUNCT
gs-3921	233	1	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	233	2	remains	remain	VERB
gs-3921	233	3	a	a	DET
gs-3921	233	4	cornerstone	cornerstone	NOUN
gs-3921	233	5	of	of	ADP
gs-3921	233	6	medication	medication	NOUN
gs-3921	233	7	safety	safety	NOUN
gs-3921	233	8	,	,	PUNCT
gs-3921	233	9	and	and	CCONJ
gs-3921	233	10	its	its	PRON
gs-3921	233	11	synergy	synergy	NOUN
gs-3921	233	12	with	with	ADP
gs-3921	233	13	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	233	14	offers	offer	VERB
gs-3921	233	15	enhanced	enhance	VERB
gs-3921	233	16	capabilities	capability	NOUN
gs-3921	233	17	for	for	ADP
gs-3921	233	18	identifying	identify	VERB
gs-3921	233	19	and	and	CCONJ
gs-3921	233	20	managing	manage	VERB
gs-3921	233	21	adverse	adverse	ADJ
gs-3921	233	22	drug	drug	NOUN
gs-3921	233	23	reactions	reaction	NOUN
gs-3921	233	24	.	.	PUNCT
gs-3921	234	1	traditional	traditional	ADJ
gs-3921	234	2	spontaneous	spontaneous	ADJ
gs-3921	234	3	reporting	reporting	NOUN
gs-3921	234	4	systems	system	NOUN
gs-3921	234	5	are	be	AUX
gs-3921	234	6	limited	limit	VERB
gs-3921	234	7	by	by	ADP
gs-3921	234	8	underreporting	underreporte	VERB
gs-3921	234	9	and	and	CCONJ
gs-3921	234	10	bias	bias	NOUN
gs-3921	234	11	,	,	PUNCT
gs-3921	234	12	often	often	ADV
gs-3921	234	13	failing	fail	VERB
gs-3921	234	14	to	to	PART
gs-3921	234	15	detect	detect	VERB
gs-3921	234	16	rare	rare	ADJ
gs-3921	234	17	or	or	CCONJ
gs-3921	234	18	delayed	delay	VERB
gs-3921	234	19	toxicities	toxicity	NOUN
gs-3921	234	20	.	.	PUNCT
gs-3921	235	1	augmentation	augmentation	NOUN
gs-3921	235	2	with	with	ADP
gs-3921	235	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	235	4	data	datum	NOUN
gs-3921	235	5	allows	allow	VERB
gs-3921	235	6	for	for	ADP
gs-3921	235	7	stratified	stratified	ADJ
gs-3921	235	8	signal	signal	NOUN
gs-3921	235	9	detection	detection	NOUN
gs-3921	235	10	,	,	PUNCT
gs-3921	235	11	distinguishing	distinguish	VERB
gs-3921	235	12	genetically	genetically	ADV
gs-3921	235	13	predisposed	predispose	VERB
gs-3921	235	14	subpopulations	subpopulation	NOUN
gs-3921	235	15	at	at	ADP
gs-3921	235	16	risk	risk	NOUN
gs-3921	235	17	.	.	PUNCT
gs-3921	236	1	active	active	ADJ
gs-3921	236	2	surveillance	surveillance	NOUN
gs-3921	236	3	methodologies	methodology	NOUN
gs-3921	236	4	utilizing	utilize	VERB
gs-3921	236	5	ehrs	ehrs	PROPN
gs-3921	236	6	,	,	PUNCT
gs-3921	236	7	biobanks	biobank	NOUN
gs-3921	236	8	,	,	PUNCT
gs-3921	236	9	and	and	CCONJ
gs-3921	236	10	patient	patient	ADJ
gs-3921	236	11	registries	registry	NOUN
gs-3921	236	12	enable	enable	VERB
gs-3921	236	13	longitudinal	longitudinal	ADJ
gs-3921	236	14	monitoring	monitoring	NOUN
gs-3921	236	15	and	and	CCONJ
gs-3921	236	16	real	real	ADJ
gs-3921	236	17	-	-	PUNCT
gs-3921	236	18	time	time	NOUN
gs-3921	236	19	safety	safety	NOUN
gs-3921	236	20	assessments	assessment	NOUN
gs-3921	236	21	.	.	PUNCT
gs-3921	237	1	for	for	ADP
gs-3921	237	2	example	example	NOUN
gs-3921	237	3	,	,	PUNCT
gs-3921	237	4	the	the	DET
gs-3921	237	5	u.s	u.s	PROPN
gs-3921	237	6	.	.	PROPN
gs-3921	237	7	food	food	PROPN
gs-3921	237	8	and	and	CCONJ
gs-3921	237	9	drug	drug	PROPN
gs-3921	237	10	administration	administration	NOUN
gs-3921	237	11	’s	’s	PART
gs-3921	237	12	sentinel	sentinel	PROPN
gs-3921	237	13	initiative	initiative	NOUN
gs-3921	237	14	employs	employ	VERB
gs-3921	237	15	large	large	ADJ
gs-3921	237	16	-	-	PUNCT
gs-3921	237	17	scale	scale	NOUN
gs-3921	237	18	data	datum	NOUN
gs-3921	237	19	analytics	analytic	NOUN
gs-3921	237	20	to	to	PART
gs-3921	237	21	identify	identify	VERB
gs-3921	237	22	potential	potential	ADJ
gs-3921	237	23	drug	drug	NOUN
gs-3921	237	24	safety	safety	NOUN
gs-3921	237	25	concerns	concern	NOUN
gs-3921	237	26	,	,	PUNCT
gs-3921	237	27	with	with	SCONJ
gs-3921	237	28	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	237	29	components	component	NOUN
gs-3921	237	30	increasingly	increasingly	ADV
gs-3921	237	31	incorporated	incorporate	VERB
gs-3921	237	32	.	.	PUNCT
gs-3921	238	1	these	these	DET
gs-3921	238	2	systems	system	NOUN
gs-3921	238	3	support	support	VERB
gs-3921	238	4	iterative	iterative	NOUN
gs-3921	238	5	risk	risk	NOUN
gs-3921	238	6	evaluation	evaluation	NOUN
gs-3921	238	7	and	and	CCONJ
gs-3921	238	8	can	can	AUX
gs-3921	238	9	inform	inform	VERB
gs-3921	238	10	label	label	NOUN
gs-3921	238	11	updates	update	NOUN
gs-3921	238	12	,	,	PUNCT
gs-3921	238	13	risk	risk	NOUN
gs-3921	238	14	mitigation	mitigation	NOUN
gs-3921	238	15	strategies	strategy	NOUN
gs-3921	238	16	,	,	PUNCT
gs-3921	238	17	and	and	CCONJ
gs-3921	238	18	clinical	clinical	ADJ
gs-3921	238	19	guidelines	guideline	NOUN
gs-3921	238	20	.	.	PUNCT
gs-3921	239	1	georgian	georgian	ADJ
gs-3921	239	2	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	239	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	239	4	ტ.	ტ.	VERB
gs-3921	239	5	7	7	NUM
gs-3921	239	6	n	n	PRON
gs-3921	239	7	3	3	NUM
gs-3921	239	8	,	,	PUNCT
gs-3921	239	9	2025	2025	NUM
gs-3921	239	10	232	232	NUM
gs-3921	240	1	the	the	DET
gs-3921	240	2	complexity	complexity	NOUN
gs-3921	240	3	of	of	ADP
gs-3921	240	4	polypharmacy	polypharmacy	NOUN
gs-3921	240	5	,	,	PUNCT
gs-3921	240	6	especially	especially	ADV
gs-3921	240	7	in	in	ADP
gs-3921	240	8	aging	age	VERB
gs-3921	240	9	and	and	CCONJ
gs-3921	240	10	multimorbid	multimorbid	ADJ
gs-3921	240	11	populations	population	NOUN
gs-3921	240	12	,	,	PUNCT
gs-3921	240	13	exacerbates	exacerbate	VERB
gs-3921	240	14	the	the	DET
gs-3921	240	15	risk	risk	NOUN
gs-3921	240	16	of	of	ADP
gs-3921	240	17	adverse	adverse	ADJ
gs-3921	240	18	effects	effect	NOUN
gs-3921	240	19	.	.	PUNCT
gs-3921	241	1	polypharmacy	polypharmacy	NOUN
gs-3921	241	2	introduces	introduce	VERB
gs-3921	241	3	the	the	DET
gs-3921	241	4	potential	potential	NOUN
gs-3921	241	5	for	for	ADP
gs-3921	241	6	multiple	multiple	ADJ
gs-3921	241	7	drug	drug	NOUN
gs-3921	241	8	-	-	PUNCT
gs-3921	241	9	drug	drug	NOUN
gs-3921	241	10	and	and	CCONJ
gs-3921	241	11	drug	drug	NOUN
gs-3921	241	12	-	-	PUNCT
gs-3921	241	13	gene	gene	NOUN
gs-3921	241	14	interactions	interaction	NOUN
gs-3921	241	15	that	that	PRON
gs-3921	241	16	can	can	AUX
gs-3921	241	17	compound	compound	VERB
gs-3921	241	18	toxicity	toxicity	NOUN
gs-3921	241	19	risks	risk	NOUN
gs-3921	241	20	.	.	PUNCT
gs-3921	242	1	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	242	2	insights	insight	NOUN
gs-3921	242	3	help	help	VERB
gs-3921	242	4	unravel	unravel	VERB
gs-3921	242	5	this	this	DET
gs-3921	242	6	complexity	complexity	NOUN
gs-3921	242	7	by	by	ADP
gs-3921	242	8	predicting	predict	VERB
gs-3921	242	9	metabolic	metabolic	NOUN
gs-3921	242	10	capacity	capacity	NOUN
gs-3921	242	11	and	and	CCONJ
gs-3921	242	12	drug	drug	NOUN
gs-3921	242	13	interactions	interaction	NOUN
gs-3921	242	14	at	at	ADP
gs-3921	242	15	an	an	DET
gs-3921	242	16	individual	individual	ADJ
gs-3921	242	17	level	level	NOUN
gs-3921	242	18	.	.	PUNCT
gs-3921	243	1	recent	recent	ADJ
gs-3921	243	2	research	research	NOUN
gs-3921	243	3	highlights	highlight	NOUN
gs-3921	243	4	the	the	DET
gs-3921	243	5	need	need	NOUN
gs-3921	243	6	for	for	ADP
gs-3921	243	7	integrated	integrated	ADJ
gs-3921	243	8	models	model	NOUN
gs-3921	243	9	that	that	PRON
gs-3921	243	10	consider	consider	VERB
gs-3921	243	11	genomic	genomic	NOUN
gs-3921	243	12	,	,	PUNCT
gs-3921	243	13	pharmacokinetic	pharmacokinetic	ADJ
gs-3921	243	14	,	,	PUNCT
gs-3921	243	15	and	and	CCONJ
gs-3921	243	16	clinical	clinical	ADJ
gs-3921	243	17	variables	variable	NOUN
gs-3921	243	18	to	to	PART
gs-3921	243	19	optimize	optimize	VERB
gs-3921	243	20	medication	medication	NOUN
gs-3921	243	21	regimens	regimen	NOUN
gs-3921	243	22	holistically	holistically	ADV
gs-3921	243	23	.	.	PUNCT
gs-3921	244	1	clinical	clinical	ADJ
gs-3921	244	2	pharmacists	pharmacist	NOUN
gs-3921	244	3	play	play	VERB
gs-3921	244	4	an	an	DET
gs-3921	244	5	essential	essential	ADJ
gs-3921	244	6	role	role	NOUN
gs-3921	244	7	in	in	ADP
gs-3921	244	8	applying	apply	VERB
gs-3921	244	9	these	these	DET
gs-3921	244	10	principles	principle	NOUN
gs-3921	244	11	through	through	ADP
gs-3921	244	12	medication	medication	NOUN
gs-3921	244	13	therapy	therapy	NOUN
gs-3921	244	14	management	management	NOUN
gs-3921	244	15	programs	program	NOUN
gs-3921	244	16	,	,	PUNCT
gs-3921	244	17	performing	perform	VERB
gs-3921	244	18	comprehensive	comprehensive	ADJ
gs-3921	244	19	reviews	review	NOUN
gs-3921	244	20	to	to	PART
gs-3921	244	21	minimize	minimize	VERB
gs-3921	244	22	harm	harm	NOUN
gs-3921	244	23	and	and	CCONJ
gs-3921	244	24	maximize	maximize	VERB
gs-3921	244	25	benefit	benefit	NOUN
gs-3921	244	26	.	.	PUNCT
gs-3921	245	1	emerging	emerge	VERB
gs-3921	245	2	scientific	scientific	ADJ
gs-3921	245	3	advances	advance	NOUN
gs-3921	245	4	extend	extend	VERB
gs-3921	245	5	the	the	DET
gs-3921	245	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	245	7	paradigm	paradigm	NOUN
gs-3921	245	8	beyond	beyond	ADP
gs-3921	245	9	single	single	ADJ
gs-3921	245	10	nucleotide	nucleotide	ADJ
gs-3921	245	11	polymorphisms	polymorphism	NOUN
gs-3921	245	12	(	(	PUNCT
gs-3921	245	13	snps	snps	PROPN
gs-3921	245	14	)	)	PUNCT
gs-3921	245	15	to	to	PART
gs-3921	245	16	include	include	VERB
gs-3921	245	17	complex	complex	ADJ
gs-3921	245	18	genomic	genomic	NOUN
gs-3921	245	19	and	and	CCONJ
gs-3921	245	20	multi	multi	ADJ
gs-3921	245	21	-	-	ADJ
gs-3921	245	22	omic	omic	ADJ
gs-3921	245	23	factors	factor	NOUN
gs-3921	245	24	.	.	PUNCT
gs-3921	246	1	epigenetic	epigenetic	ADJ
gs-3921	246	2	modifications	modification	NOUN
gs-3921	246	3	,	,	PUNCT
gs-3921	246	4	such	such	ADJ
gs-3921	246	5	as	as	ADP
gs-3921	246	6	dna	dna	PROPN
gs-3921	246	7	methylation	methylation	NOUN
gs-3921	246	8	and	and	CCONJ
gs-3921	246	9	histone	histone	NOUN
gs-3921	246	10	modification	modification	NOUN
gs-3921	246	11	,	,	PUNCT
gs-3921	246	12	can	can	AUX
gs-3921	246	13	alter	alter	VERB
gs-3921	246	14	gene	gene	NOUN
gs-3921	246	15	expression	expression	NOUN
gs-3921	246	16	related	relate	VERB
gs-3921	246	17	to	to	ADP
gs-3921	246	18	drug	drug	NOUN
gs-3921	246	19	metabolism	metabolism	NOUN
gs-3921	246	20	and	and	CCONJ
gs-3921	246	21	response	response	NOUN
gs-3921	246	22	.	.	PUNCT
gs-3921	247	1	transcriptomic	transcriptomic	ADJ
gs-3921	247	2	and	and	CCONJ
gs-3921	247	3	proteomic	proteomic	ADJ
gs-3921	247	4	profiling	profiling	NOUN
gs-3921	247	5	provide	provide	VERB
gs-3921	247	6	additional	additional	ADJ
gs-3921	247	7	layers	layer	NOUN
gs-3921	247	8	of	of	ADP
gs-3921	247	9	information	information	NOUN
gs-3921	247	10	,	,	PUNCT
gs-3921	247	11	capturing	capture	VERB
gs-3921	247	12	dynamic	dynamic	ADJ
gs-3921	247	13	changes	change	NOUN
gs-3921	247	14	and	and	CCONJ
gs-3921	247	15	environmental	environmental	ADJ
gs-3921	247	16	influences	influence	NOUN
gs-3921	247	17	.	.	PUNCT
gs-3921	248	1	these	these	DET
gs-3921	248	2	multi	multi	ADJ
gs-3921	248	3	-	-	ADJ
gs-3921	248	4	omic	omic	ADJ
gs-3921	248	5	data	datum	NOUN
gs-3921	248	6	,	,	PUNCT
gs-3921	248	7	combined	combine	VERB
gs-3921	248	8	with	with	ADP
gs-3921	248	9	clinical	clinical	ADJ
gs-3921	248	10	and	and	CCONJ
gs-3921	248	11	environmental	environmental	ADJ
gs-3921	248	12	factors	factor	NOUN
gs-3921	248	13	,	,	PUNCT
gs-3921	248	14	enable	enable	ADJ
gs-3921	248	15	systems	system	NOUN
gs-3921	248	16	pharmacology	pharmacology	NOUN
gs-3921	248	17	approaches	approach	NOUN
gs-3921	248	18	that	that	PRON
gs-3921	248	19	offer	offer	VERB
gs-3921	248	20	a	a	DET
gs-3921	248	21	more	more	ADV
gs-3921	248	22	nuanced	nuanced	ADJ
gs-3921	248	23	and	and	CCONJ
gs-3921	248	24	predictive	predictive	ADJ
gs-3921	248	25	understanding	understanding	NOUN
gs-3921	248	26	of	of	ADP
gs-3921	248	27	drug	drug	NOUN
gs-3921	248	28	response	response	NOUN
gs-3921	248	29	and	and	CCONJ
gs-3921	248	30	toxicity	toxicity	NOUN
gs-3921	248	31	.	.	PUNCT
gs-3921	249	1	the	the	DET
gs-3921	249	2	integration	integration	NOUN
gs-3921	249	3	of	of	ADP
gs-3921	249	4	these	these	DET
gs-3921	249	5	data	datum	NOUN
gs-3921	249	6	types	type	NOUN
gs-3921	249	7	demands	demand	VERB
gs-3921	249	8	sophisticated	sophisticated	ADJ
gs-3921	249	9	bioinformatics	bioinformatic	NOUN
gs-3921	249	10	and	and	CCONJ
gs-3921	249	11	statistical	statistical	ADJ
gs-3921	249	12	methods	method	NOUN
gs-3921	249	13	,	,	PUNCT
gs-3921	249	14	as	as	ADV
gs-3921	249	15	well	well	ADV
gs-3921	249	16	as	as	ADP
gs-3921	249	17	large	large	ADJ
gs-3921	249	18	,	,	PUNCT
gs-3921	249	19	wellcharacterized	wellcharacterize	VERB
gs-3921	249	20	cohorts	cohort	NOUN
gs-3921	249	21	for	for	ADP
gs-3921	249	22	validation	validation	NOUN
gs-3921	249	23	.	.	PUNCT
gs-3921	250	1	ethical	ethical	ADJ
gs-3921	250	2	and	and	CCONJ
gs-3921	250	3	social	social	ADJ
gs-3921	250	4	implications	implication	NOUN
gs-3921	250	5	permeate	permeate	VERB
gs-3921	250	6	all	all	DET
gs-3921	250	7	facets	facet	NOUN
gs-3921	250	8	of	of	ADP
gs-3921	250	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	250	10	implementation	implementation	NOUN
gs-3921	250	11	and	and	CCONJ
gs-3921	250	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	250	13	.	.	PUNCT
gs-3921	251	1	the	the	DET
gs-3921	251	2	handling	handling	NOUN
gs-3921	251	3	of	of	ADP
gs-3921	251	4	sensitive	sensitive	ADJ
gs-3921	251	5	genetic	genetic	ADJ
gs-3921	251	6	information	information	NOUN
gs-3921	251	7	requires	require	VERB
gs-3921	251	8	stringent	stringent	ADJ
gs-3921	251	9	safeguards	safeguard	NOUN
gs-3921	251	10	to	to	PART
gs-3921	251	11	ensure	ensure	VERB
gs-3921	251	12	confidentiality	confidentiality	NOUN
gs-3921	251	13	,	,	PUNCT
gs-3921	251	14	prevent	prevent	VERB
gs-3921	251	15	unauthorized	unauthorized	ADJ
gs-3921	251	16	access	access	NOUN
gs-3921	251	17	,	,	PUNCT
gs-3921	251	18	and	and	CCONJ
gs-3921	251	19	mitigate	mitigate	VERB
gs-3921	251	20	risks	risk	NOUN
gs-3921	251	21	of	of	ADP
gs-3921	251	22	discrimination	discrimination	NOUN
gs-3921	251	23	in	in	ADP
gs-3921	251	24	employment	employment	NOUN
gs-3921	251	25	or	or	CCONJ
gs-3921	251	26	insurance	insurance	NOUN
gs-3921	251	27	.	.	PUNCT
gs-3921	252	1	informed	inform	VERB
gs-3921	252	2	consent	consent	NOUN
gs-3921	252	3	processes	process	NOUN
gs-3921	252	4	must	must	AUX
gs-3921	252	5	be	be	AUX
gs-3921	252	6	robust	robust	ADJ
gs-3921	252	7	,	,	PUNCT
gs-3921	252	8	clear	clear	ADJ
gs-3921	252	9	,	,	PUNCT
gs-3921	252	10	and	and	CCONJ
gs-3921	252	11	culturally	culturally	ADV
gs-3921	252	12	sensitive	sensitive	ADJ
gs-3921	252	13	,	,	PUNCT
gs-3921	252	14	enabling	enable	VERB
gs-3921	252	15	patients	patient	NOUN
gs-3921	252	16	to	to	PART
gs-3921	252	17	understand	understand	VERB
gs-3921	252	18	the	the	DET
gs-3921	252	19	scope	scope	NOUN
gs-3921	252	20	,	,	PUNCT
gs-3921	252	21	benefits	benefit	NOUN
gs-3921	252	22	,	,	PUNCT
gs-3921	252	23	limitations	limitation	NOUN
gs-3921	252	24	,	,	PUNCT
gs-3921	252	25	and	and	CCONJ
gs-3921	252	26	potential	potential	ADJ
gs-3921	252	27	risks	risk	NOUN
gs-3921	252	28	of	of	ADP
gs-3921	252	29	genetic	genetic	ADJ
gs-3921	252	30	testing	testing	NOUN
gs-3921	252	31	.	.	PUNCT
gs-3921	253	1	policymakers	policymaker	NOUN
gs-3921	253	2	and	and	CCONJ
gs-3921	253	3	healthcare	healthcare	NOUN
gs-3921	253	4	organizations	organization	NOUN
gs-3921	253	5	must	must	AUX
gs-3921	253	6	address	address	VERB
gs-3921	253	7	disparities	disparity	NOUN
gs-3921	253	8	in	in	ADP
gs-3921	253	9	access	access	NOUN
gs-3921	253	10	to	to	ADP
gs-3921	253	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	253	12	services	service	NOUN
gs-3921	253	13	to	to	PART
gs-3921	253	14	avoid	avoid	VERB
gs-3921	253	15	exacerbating	exacerbate	VERB
gs-3921	253	16	health	health	NOUN
gs-3921	253	17	inequities	inequity	NOUN
gs-3921	253	18	.	.	PUNCT
gs-3921	254	1	community	community	NOUN
gs-3921	254	2	engagement	engagement	NOUN
gs-3921	254	3	and	and	CCONJ
gs-3921	254	4	participatory	participatory	ADJ
gs-3921	254	5	research	research	NOUN
gs-3921	254	6	models	model	NOUN
gs-3921	254	7	are	be	AUX
gs-3921	254	8	valuable	valuable	ADJ
gs-3921	254	9	for	for	ADP
gs-3921	254	10	aligning	align	VERB
gs-3921	254	11	implementation	implementation	NOUN
gs-3921	254	12	strategies	strategy	NOUN
gs-3921	254	13	with	with	ADP
gs-3921	254	14	local	local	ADJ
gs-3921	254	15	values	value	NOUN
gs-3921	254	16	and	and	CCONJ
gs-3921	254	17	needs	need	NOUN
gs-3921	254	18	,	,	PUNCT
gs-3921	254	19	fostering	foster	VERB
gs-3921	254	20	trust	trust	NOUN
gs-3921	254	21	and	and	CCONJ
gs-3921	254	22	acceptance	acceptance	NOUN
gs-3921	254	23	.	.	PUNCT
gs-3921	255	1	health	health	NOUN
gs-3921	255	2	economic	economic	ADJ
gs-3921	255	3	analyses	analysis	NOUN
gs-3921	255	4	indicate	indicate	VERB
gs-3921	255	5	that	that	SCONJ
gs-3921	255	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	255	7	-	-	PUNCT
gs-3921	255	8	guided	guide	VERB
gs-3921	255	9	therapy	therapy	NOUN
gs-3921	255	10	can	can	AUX
gs-3921	255	11	be	be	AUX
gs-3921	255	12	cost	cost	NOUN
gs-3921	255	13	-	-	PUNCT
gs-3921	255	14	effective	effective	ADJ
gs-3921	255	15	or	or	CCONJ
gs-3921	255	16	even	even	ADV
gs-3921	255	17	cost	cost	NOUN
gs-3921	255	18	-	-	PUNCT
gs-3921	255	19	saving	saving	NOUN
gs-3921	255	20	by	by	ADP
gs-3921	255	21	preventing	prevent	VERB
gs-3921	255	22	severe	severe	ADJ
gs-3921	255	23	adverse	adverse	ADJ
gs-3921	255	24	drug	drug	NOUN
gs-3921	255	25	reactions	reaction	NOUN
gs-3921	255	26	and	and	CCONJ
gs-3921	255	27	reducing	reduce	VERB
gs-3921	255	28	hospitalizations	hospitalization	NOUN
gs-3921	255	29	.	.	PUNCT
gs-3921	256	1	however	however	ADV
gs-3921	256	2	,	,	PUNCT
gs-3921	256	3	economic	economic	ADJ
gs-3921	256	4	evaluations	evaluation	NOUN
gs-3921	256	5	are	be	AUX
gs-3921	256	6	heterogeneous	heterogeneous	ADJ
gs-3921	256	7	,	,	PUNCT
gs-3921	256	8	influenced	influence	VERB
gs-3921	256	9	by	by	ADP
gs-3921	256	10	test	test	NOUN
gs-3921	256	11	costs	cost	NOUN
gs-3921	256	12	,	,	PUNCT
gs-3921	256	13	healthcare	healthcare	NOUN
gs-3921	256	14	system	system	NOUN
gs-3921	256	15	structures	structure	NOUN
gs-3921	256	16	,	,	PUNCT
gs-3921	256	17	population	population	NOUN
gs-3921	256	18	characteristics	characteristic	NOUN
gs-3921	256	19	,	,	PUNCT
gs-3921	256	20	and	and	CCONJ
gs-3921	256	21	disease	disease	NOUN
gs-3921	256	22	contexts	contexts	NOUN
gs-3921	256	23	.	.	PUNCT
gs-3921	257	1	incorporating	incorporate	VERB
gs-3921	257	2	broader	broad	ADJ
gs-3921	257	3	societal	societal	ADJ
gs-3921	257	4	costs	cost	NOUN
gs-3921	257	5	and	and	CCONJ
gs-3921	257	6	benefits	benefit	NOUN
gs-3921	257	7	,	,	PUNCT
gs-3921	257	8	such	such	ADJ
gs-3921	257	9	as	as	ADP
gs-3921	257	10	quality	quality	NOUN
gs-3921	257	11	of	of	ADP
gs-3921	257	12	life	life	NOUN
gs-3921	257	13	improvements	improvement	NOUN
gs-3921	257	14	and	and	CCONJ
gs-3921	257	15	productivity	productivity	NOUN
gs-3921	257	16	gains	gain	NOUN
gs-3921	257	17	,	,	PUNCT
gs-3921	257	18	strengthens	strengthen	VERB
gs-3921	257	19	the	the	DET
gs-3921	257	20	case	case	NOUN
gs-3921	257	21	for	for	ADP
gs-3921	257	22	investment	investment	NOUN
gs-3921	257	23	in	in	ADP
gs-3921	257	24	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	257	25	services	service	NOUN
gs-3921	257	26	.	.	PUNCT
gs-3921	258	1	payment	payment	NOUN
gs-3921	258	2	and	and	CCONJ
gs-3921	258	3	reimbursement	reimbursement	NOUN
gs-3921	258	4	models	model	NOUN
gs-3921	258	5	must	must	AUX
gs-3921	258	6	evolve	evolve	VERB
gs-3921	258	7	to	to	PART
gs-3921	258	8	incentivize	incentivize	VERB
gs-3921	258	9	adoption	adoption	NOUN
gs-3921	258	10	,	,	PUNCT
gs-3921	258	11	incorporating	incorporate	VERB
gs-3921	258	12	value	value	NOUN
gs-3921	258	13	-	-	PUNCT
gs-3921	258	14	based	base	VERB
gs-3921	258	15	principles	principle	NOUN
gs-3921	258	16	that	that	PRON
gs-3921	258	17	reward	reward	VERB
gs-3921	258	18	improved	improve	VERB
gs-3921	258	19	patient	patient	ADJ
gs-3921	258	20	outcomes	outcome	NOUN
gs-3921	258	21	and	and	CCONJ
gs-3921	258	22	system	system	NOUN
gs-3921	258	23	efficiencies	efficiency	NOUN
gs-3921	258	24	.	.	PUNCT
gs-3921	259	1	the	the	DET
gs-3921	259	2	rapid	rapid	ADJ
gs-3921	259	3	pace	pace	NOUN
gs-3921	259	4	of	of	ADP
gs-3921	259	5	technological	technological	ADJ
gs-3921	259	6	innovation	innovation	NOUN
gs-3921	259	7	is	be	AUX
gs-3921	259	8	shaping	shape	VERB
gs-3921	259	9	the	the	DET
gs-3921	259	10	future	future	NOUN
gs-3921	259	11	of	of	ADP
gs-3921	259	12	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	259	13	and	and	CCONJ
gs-3921	259	14	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	259	15	.	.	PUNCT
gs-3921	260	1	artificial	artificial	ADJ
gs-3921	260	2	intelligence	intelligence	NOUN
gs-3921	260	3	(	(	PUNCT
gs-3921	260	4	ai	ai	NOUN
gs-3921	260	5	)	)	PUNCT
gs-3921	260	6	and	and	CCONJ
gs-3921	260	7	machine	machine	NOUN
gs-3921	260	8	learning	learn	VERB
gs-3921	260	9	algorithms	algorithm	NOUN
gs-3921	260	10	enhance	enhance	VERB
gs-3921	260	11	the	the	DET
gs-3921	260	12	ability	ability	NOUN
gs-3921	260	13	to	to	PART
gs-3921	260	14	analyze	analyze	VERB
gs-3921	260	15	complex	complex	ADJ
gs-3921	260	16	datasets	dataset	NOUN
gs-3921	260	17	,	,	PUNCT
gs-3921	260	18	identify	identify	VERB
gs-3921	260	19	novel	novel	ADJ
gs-3921	260	20	gene	gene	NOUN
gs-3921	260	21	-	-	PUNCT
gs-3921	260	22	drug	drug	NOUN
gs-3921	260	23	georgian	georgian	ADJ
gs-3921	260	24	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	260	25	მეცნიერები	მეცნიერები	NOUN
gs-3921	260	26	ტ.	ტ.	VERB
gs-3921	260	27	7	7	NUM
gs-3921	260	28	n	n	DET
gs-3921	260	29	3	3	NUM
gs-3921	260	30	,	,	PUNCT
gs-3921	260	31	2025	2025	NUM
gs-3921	260	32	233	233	NUM
gs-3921	260	33	interactions	interaction	NOUN
gs-3921	260	34	,	,	PUNCT
gs-3921	260	35	and	and	CCONJ
gs-3921	260	36	predict	predict	VERB
gs-3921	260	37	adverse	adverse	ADJ
gs-3921	260	38	events	event	NOUN
gs-3921	260	39	with	with	ADP
gs-3921	260	40	high	high	ADJ
gs-3921	260	41	accuracy	accuracy	NOUN
gs-3921	260	42	.	.	PUNCT
gs-3921	261	1	wearable	wearable	ADJ
gs-3921	261	2	biosensors	biosensor	NOUN
gs-3921	261	3	and	and	CCONJ
gs-3921	261	4	mobile	mobile	ADJ
gs-3921	261	5	health	health	NOUN
gs-3921	261	6	platforms	platform	NOUN
gs-3921	261	7	enable	enable	VERB
gs-3921	261	8	continuous	continuous	ADJ
gs-3921	261	9	patient	patient	ADJ
gs-3921	261	10	monitoring	monitoring	NOUN
gs-3921	261	11	,	,	PUNCT
gs-3921	261	12	facilitating	facilitate	VERB
gs-3921	261	13	early	early	ADJ
gs-3921	261	14	detection	detection	NOUN
gs-3921	261	15	of	of	ADP
gs-3921	261	16	toxicity	toxicity	NOUN
gs-3921	261	17	and	and	CCONJ
gs-3921	261	18	personalized	personalized	ADJ
gs-3921	261	19	interventions	intervention	NOUN
gs-3921	261	20	.	.	PUNCT
gs-3921	262	1	blockchain	blockchain	PROPN
gs-3921	262	2	technology	technology	PROPN
gs-3921	262	3	offers	offer	VERB
gs-3921	262	4	potential	potential	ADJ
gs-3921	262	5	solutions	solution	NOUN
gs-3921	262	6	for	for	ADP
gs-3921	262	7	secure	secure	ADJ
gs-3921	262	8	,	,	PUNCT
gs-3921	262	9	patient	patient	NOUN
gs-3921	262	10	-	-	PUNCT
gs-3921	262	11	controlled	control	VERB
gs-3921	262	12	data	datum	NOUN
gs-3921	262	13	sharing	sharing	NOUN
gs-3921	262	14	,	,	PUNCT
gs-3921	262	15	enhancing	enhance	VERB
gs-3921	262	16	trust	trust	NOUN
gs-3921	262	17	and	and	CCONJ
gs-3921	262	18	interoperability	interoperability	NOUN
gs-3921	262	19	.	.	PUNCT
gs-3921	263	1	nonetheless	nonetheless	ADV
gs-3921	263	2	,	,	PUNCT
gs-3921	263	3	the	the	DET
gs-3921	263	4	adoption	adoption	NOUN
gs-3921	263	5	of	of	ADP
gs-3921	263	6	these	these	DET
gs-3921	263	7	technologies	technology	NOUN
gs-3921	263	8	requires	require	VERB
gs-3921	263	9	careful	careful	ADJ
gs-3921	263	10	validation	validation	NOUN
gs-3921	263	11	,	,	PUNCT
gs-3921	263	12	regulatory	regulatory	ADJ
gs-3921	263	13	oversight	oversight	NOUN
gs-3921	263	14	,	,	PUNCT
gs-3921	263	15	and	and	CCONJ
gs-3921	263	16	ethical	ethical	ADJ
gs-3921	263	17	governance	governance	NOUN
gs-3921	263	18	to	to	PART
gs-3921	263	19	ensure	ensure	VERB
gs-3921	263	20	safety	safety	NOUN
gs-3921	263	21	,	,	PUNCT
gs-3921	263	22	efficacy	efficacy	NOUN
gs-3921	263	23	,	,	PUNCT
gs-3921	263	24	and	and	CCONJ
gs-3921	263	25	equity	equity	NOUN
gs-3921	263	26	.	.	PUNCT
gs-3921	264	1	globally	globally	ADV
gs-3921	264	2	,	,	PUNCT
gs-3921	264	3	efforts	effort	NOUN
gs-3921	264	4	to	to	PART
gs-3921	264	5	harmonize	harmonize	VERB
gs-3921	264	6	regulatory	regulatory	ADJ
gs-3921	264	7	standards	standard	NOUN
gs-3921	264	8	,	,	PUNCT
gs-3921	264	9	guidelines	guideline	NOUN
gs-3921	264	10	,	,	PUNCT
gs-3921	264	11	and	and	CCONJ
gs-3921	264	12	nomenclature	nomenclature	NOUN
gs-3921	264	13	facilitate	facilitate	NOUN
gs-3921	264	14	the	the	DET
gs-3921	264	15	international	international	ADJ
gs-3921	264	16	exchange	exchange	NOUN
gs-3921	264	17	of	of	ADP
gs-3921	264	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	264	19	data	datum	NOUN
gs-3921	264	20	and	and	CCONJ
gs-3921	264	21	best	good	ADJ
gs-3921	264	22	practices	practice	NOUN
gs-3921	264	23	.	.	PUNCT
gs-3921	265	1	organizations	organization	NOUN
gs-3921	265	2	such	such	ADJ
gs-3921	265	3	as	as	ADP
gs-3921	265	4	the	the	DET
gs-3921	265	5	clinical	clinical	ADJ
gs-3921	265	6	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	265	7	implementation	implementation	NOUN
gs-3921	265	8	consortium	consortium	NOUN
gs-3921	265	9	(	(	PUNCT
gs-3921	265	10	cpic	cpic	NOUN
gs-3921	265	11	)	)	PUNCT
gs-3921	265	12	and	and	CCONJ
gs-3921	265	13	the	the	DET
gs-3921	265	14	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	265	15	knowledgebase	knowledgebase	PROPN
gs-3921	265	16	(	(	PUNCT
gs-3921	265	17	pharmgkb	pharmgkb	ADJ
gs-3921	265	18	)	)	PUNCT
gs-3921	265	19	provide	provide	VERB
gs-3921	265	20	curated	curate	VERB
gs-3921	265	21	,	,	PUNCT
gs-3921	265	22	evidence	evidence	NOUN
gs-3921	265	23	-	-	PUNCT
gs-3921	265	24	based	base	VERB
gs-3921	265	25	resources	resource	NOUN
gs-3921	265	26	to	to	PART
gs-3921	265	27	guide	guide	VERB
gs-3921	265	28	clinical	clinical	ADJ
gs-3921	265	29	application	application	NOUN
gs-3921	265	30	.	.	PUNCT
gs-3921	266	1	national	national	ADJ
gs-3921	266	2	and	and	CCONJ
gs-3921	266	3	regional	regional	ADJ
gs-3921	266	4	regulatory	regulatory	ADJ
gs-3921	266	5	agencies	agency	NOUN
gs-3921	266	6	increasingly	increasingly	ADV
gs-3921	266	7	incorporate	incorporate	VERB
gs-3921	266	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	266	9	considerations	consideration	NOUN
gs-3921	266	10	into	into	ADP
gs-3921	266	11	drug	drug	NOUN
gs-3921	266	12	approval	approval	NOUN
gs-3921	266	13	,	,	PUNCT
gs-3921	266	14	labeling	labeling	NOUN
gs-3921	266	15	,	,	PUNCT
gs-3921	266	16	and	and	CCONJ
gs-3921	266	17	post	post	ADJ
gs-3921	266	18	-	-	ADJ
gs-3921	266	19	marketing	marketing	ADJ
gs-3921	266	20	surveillance	surveillance	NOUN
gs-3921	266	21	.	.	PUNCT
gs-3921	267	1	collaborative	collaborative	ADJ
gs-3921	267	2	initiatives	initiative	NOUN
gs-3921	267	3	are	be	AUX
gs-3921	267	4	essential	essential	ADJ
gs-3921	267	5	to	to	PART
gs-3921	267	6	build	build	VERB
gs-3921	267	7	infrastructure	infrastructure	NOUN
gs-3921	267	8	,	,	PUNCT
gs-3921	267	9	share	share	NOUN
gs-3921	267	10	data	datum	NOUN
gs-3921	267	11	,	,	PUNCT
gs-3921	267	12	and	and	CCONJ
gs-3921	267	13	develop	develop	VERB
gs-3921	267	14	context	context	NOUN
gs-3921	267	15	-	-	PUNCT
gs-3921	267	16	appropriate	appropriate	ADJ
gs-3921	267	17	strategies	strategy	NOUN
gs-3921	267	18	that	that	PRON
gs-3921	267	19	address	address	VERB
gs-3921	267	20	local	local	ADJ
gs-3921	267	21	genetic	genetic	ADJ
gs-3921	267	22	diversity	diversity	NOUN
gs-3921	267	23	and	and	CCONJ
gs-3921	267	24	healthcare	healthcare	NOUN
gs-3921	267	25	realities	reality	NOUN
gs-3921	267	26	.	.	PUNCT
gs-3921	268	1	the	the	DET
gs-3921	268	2	comprehensive	comprehensive	ADJ
gs-3921	268	3	analysis	analysis	NOUN
gs-3921	268	4	confirms	confirm	VERB
gs-3921	268	5	that	that	SCONJ
gs-3921	268	6	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	268	7	and	and	CCONJ
gs-3921	268	8	patient	patient	NOUN
gs-3921	268	9	-	-	PUNCT
gs-3921	268	10	centered	center	VERB
gs-3921	268	11	care	care	NOUN
gs-3921	268	12	,	,	PUNCT
gs-3921	268	13	when	when	SCONJ
gs-3921	268	14	synergistically	synergistically	ADV
gs-3921	268	15	integrated	integrate	VERB
gs-3921	268	16	with	with	ADP
gs-3921	268	17	advanced	advanced	ADJ
gs-3921	268	18	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	268	19	systems	system	NOUN
gs-3921	268	20	,	,	PUNCT
gs-3921	268	21	have	have	VERB
gs-3921	268	22	the	the	DET
gs-3921	268	23	potential	potential	NOUN
gs-3921	268	24	to	to	PART
gs-3921	268	25	revolutionize	revolutionize	VERB
gs-3921	268	26	medication	medication	NOUN
gs-3921	268	27	safety	safety	NOUN
gs-3921	268	28	and	and	CCONJ
gs-3921	268	29	efficacy	efficacy	NOUN
gs-3921	268	30	.	.	PUNCT
gs-3921	269	1	realizing	realize	VERB
gs-3921	269	2	this	this	DET
gs-3921	269	3	potential	potential	NOUN
gs-3921	269	4	necessitates	necessitate	VERB
gs-3921	269	5	addressing	address	VERB
gs-3921	269	6	economic	economic	ADJ
gs-3921	269	7	,	,	PUNCT
gs-3921	269	8	educational	educational	ADJ
gs-3921	269	9	,	,	PUNCT
gs-3921	269	10	technological	technological	ADJ
gs-3921	269	11	,	,	PUNCT
gs-3921	269	12	ethical	ethical	ADJ
gs-3921	269	13	,	,	PUNCT
gs-3921	269	14	and	and	CCONJ
gs-3921	269	15	policy	policy	NOUN
gs-3921	269	16	challenges	challenge	NOUN
gs-3921	269	17	through	through	ADP
gs-3921	269	18	coordinated	coordinate	VERB
gs-3921	269	19	,	,	PUNCT
gs-3921	269	20	multidisciplinary	multidisciplinary	ADJ
gs-3921	269	21	efforts	effort	NOUN
gs-3921	269	22	.	.	PUNCT
gs-3921	270	1	enhancing	enhance	VERB
gs-3921	270	2	clinician	clinician	NOUN
gs-3921	270	3	and	and	CCONJ
gs-3921	270	4	patient	patient	ADJ
gs-3921	270	5	engagement	engagement	NOUN
gs-3921	270	6	,	,	PUNCT
gs-3921	270	7	leveraging	leverage	VERB
gs-3921	270	8	digital	digital	ADJ
gs-3921	270	9	health	health	NOUN
gs-3921	270	10	tools	tool	NOUN
gs-3921	270	11	,	,	PUNCT
gs-3921	270	12	expanding	expand	VERB
gs-3921	270	13	research	research	NOUN
gs-3921	270	14	inclusivity	inclusivity	NOUN
gs-3921	270	15	,	,	PUNCT
gs-3921	270	16	and	and	CCONJ
gs-3921	270	17	fostering	foster	VERB
gs-3921	270	18	supportive	supportive	ADJ
gs-3921	270	19	policy	policy	NOUN
gs-3921	270	20	environments	environment	NOUN
gs-3921	270	21	will	will	AUX
gs-3921	270	22	be	be	AUX
gs-3921	270	23	key	key	ADJ
gs-3921	270	24	to	to	ADP
gs-3921	270	25	translating	translate	VERB
gs-3921	270	26	scientific	scientific	ADJ
gs-3921	270	27	advances	advance	NOUN
gs-3921	270	28	into	into	ADP
gs-3921	270	29	routine	routine	ADJ
gs-3921	270	30	clinical	clinical	ADJ
gs-3921	270	31	practice	practice	NOUN
gs-3921	270	32	.	.	PUNCT
gs-3921	271	1	ultimately	ultimately	ADV
gs-3921	271	2	,	,	PUNCT
gs-3921	271	3	these	these	DET
gs-3921	271	4	strategies	strategy	NOUN
gs-3921	271	5	aim	aim	VERB
gs-3921	271	6	to	to	PART
gs-3921	271	7	minimize	minimize	VERB
gs-3921	271	8	the	the	DET
gs-3921	271	9	global	global	ADJ
gs-3921	271	10	burden	burden	NOUN
gs-3921	271	11	of	of	ADP
gs-3921	271	12	adverse	adverse	ADJ
gs-3921	271	13	drug	drug	NOUN
gs-3921	271	14	reactions	reaction	NOUN
gs-3921	271	15	,	,	PUNCT
gs-3921	271	16	optimize	optimize	VERB
gs-3921	271	17	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	271	18	,	,	PUNCT
gs-3921	271	19	and	and	CCONJ
gs-3921	271	20	improve	improve	VERB
gs-3921	271	21	health	health	NOUN
gs-3921	271	22	outcomes	outcome	NOUN
gs-3921	271	23	for	for	ADP
gs-3921	271	24	diverse	diverse	ADJ
gs-3921	271	25	patient	patient	ADJ
gs-3921	271	26	populations	population	NOUN
gs-3921	271	27	.	.	PUNCT
gs-3921	272	1	the	the	DET
gs-3921	272	2	comprehensive	comprehensive	ADJ
gs-3921	272	3	synthesis	synthesis	NOUN
gs-3921	272	4	of	of	ADP
gs-3921	272	5	current	current	ADJ
gs-3921	272	6	scientific	scientific	ADJ
gs-3921	272	7	literature	literature	NOUN
gs-3921	272	8	,	,	PUNCT
gs-3921	272	9	clinical	clinical	ADJ
gs-3921	272	10	evidence	evidence	NOUN
gs-3921	272	11	,	,	PUNCT
gs-3921	272	12	and	and	CCONJ
gs-3921	272	13	emerging	emerge	VERB
gs-3921	272	14	technological	technological	ADJ
gs-3921	272	15	paradigms	paradigm	NOUN
gs-3921	272	16	underscores	underscore	VERB
gs-3921	272	17	the	the	DET
gs-3921	272	18	pivotal	pivotal	ADJ
gs-3921	272	19	role	role	NOUN
gs-3921	272	20	of	of	ADP
gs-3921	272	21	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	272	22	and	and	CCONJ
gs-3921	272	23	patient	patient	NOUN
gs-3921	272	24	-	-	PUNCT
gs-3921	272	25	centered	center	VERB
gs-3921	272	26	care	care	NOUN
gs-3921	272	27	in	in	ADP
gs-3921	272	28	transforming	transform	VERB
gs-3921	272	29	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	272	30	management	management	NOUN
gs-3921	272	31	,	,	PUNCT
gs-3921	272	32	particularly	particularly	ADV
gs-3921	272	33	in	in	ADP
gs-3921	272	34	mitigating	mitigate	VERB
gs-3921	272	35	medication	medication	NOUN
gs-3921	272	36	-	-	PUNCT
gs-3921	272	37	induced	induce	VERB
gs-3921	272	38	adverse	adverse	ADJ
gs-3921	272	39	effects	effect	NOUN
gs-3921	272	40	and	and	CCONJ
gs-3921	272	41	toxicities	toxicity	NOUN
gs-3921	272	42	.	.	PUNCT
gs-3921	273	1	the	the	DET
gs-3921	273	2	multidimensional	multidimensional	ADJ
gs-3921	273	3	nature	nature	NOUN
gs-3921	273	4	of	of	ADP
gs-3921	273	5	drug	drug	NOUN
gs-3921	273	6	response	response	NOUN
gs-3921	273	7	variability	variability	NOUN
gs-3921	273	8	—	—	PUNCT
gs-3921	273	9	shaped	shape	VERB
gs-3921	273	10	by	by	ADP
gs-3921	273	11	genetic	genetic	ADJ
gs-3921	273	12	,	,	PUNCT
gs-3921	273	13	environmental	environmental	ADJ
gs-3921	273	14	,	,	PUNCT
gs-3921	273	15	demographic	demographic	ADJ
gs-3921	273	16	,	,	PUNCT
gs-3921	273	17	and	and	CCONJ
gs-3921	273	18	clinical	clinical	ADJ
gs-3921	273	19	factors	factor	NOUN
gs-3921	273	20	—	—	PUNCT
gs-3921	273	21	poses	pose	VERB
gs-3921	273	22	formidable	formidable	ADJ
gs-3921	273	23	challenges	challenge	NOUN
gs-3921	273	24	to	to	ADP
gs-3921	273	25	conventional	conventional	ADJ
gs-3921	273	26	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	273	27	paradigms	paradigm	VERB
gs-3921	273	28	,	,	PUNCT
gs-3921	273	29	necessitating	necessitate	VERB
gs-3921	273	30	innovative	innovative	ADJ
gs-3921	273	31	,	,	PUNCT
gs-3921	273	32	integrative	integrative	ADJ
gs-3921	273	33	approaches	approach	NOUN
gs-3921	273	34	that	that	SCONJ
gs-3921	273	35	this	this	DET
gs-3921	273	36	analysis	analysis	NOUN
gs-3921	273	37	aims	aim	VERB
gs-3921	273	38	to	to	PART
gs-3921	273	39	elucidate	elucidate	VERB
gs-3921	273	40	.	.	PUNCT
gs-3921	274	1	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	274	2	determinants	determinant	NOUN
gs-3921	274	3	of	of	ADP
gs-3921	274	4	adverse	adverse	ADJ
gs-3921	274	5	drug	drug	NOUN
gs-3921	274	6	reactions	reaction	NOUN
gs-3921	274	7	and	and	CCONJ
gs-3921	274	8	toxicities	toxicity	NOUN
gs-3921	274	9	adverse	adverse	ADJ
gs-3921	274	10	drug	drug	NOUN
gs-3921	274	11	reactions	reaction	NOUN
gs-3921	274	12	(	(	PUNCT
gs-3921	274	13	adrs	adrs	PROPN
gs-3921	274	14	)	)	PUNCT
gs-3921	274	15	remain	remain	VERB
gs-3921	274	16	a	a	DET
gs-3921	274	17	significant	significant	ADJ
gs-3921	274	18	cause	cause	NOUN
gs-3921	274	19	of	of	ADP
gs-3921	274	20	morbidity	morbidity	NOUN
gs-3921	274	21	and	and	CCONJ
gs-3921	274	22	mortality	mortality	NOUN
gs-3921	274	23	worldwide	worldwide	ADV
gs-3921	274	24	,	,	PUNCT
gs-3921	274	25	complicating	complicate	VERB
gs-3921	274	26	treatment	treatment	NOUN
gs-3921	274	27	outcomes	outcome	NOUN
gs-3921	274	28	and	and	CCONJ
gs-3921	274	29	escalating	escalate	VERB
gs-3921	274	30	healthcare	healthcare	NOUN
gs-3921	274	31	costs	cost	NOUN
gs-3921	274	32	.	.	PUNCT
gs-3921	275	1	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	275	2	offers	offer	VERB
gs-3921	275	3	critical	critical	ADJ
gs-3921	275	4	insight	insight	NOUN
gs-3921	275	5	into	into	ADP
gs-3921	275	6	interindividual	interindividual	ADJ
gs-3921	275	7	differences	difference	NOUN
gs-3921	275	8	by	by	ADP
gs-3921	275	9	delineating	delineate	VERB
gs-3921	275	10	genetic	genetic	ADJ
gs-3921	275	11	polymorphisms	polymorphism	NOUN
gs-3921	275	12	that	that	PRON
gs-3921	275	13	influence	influence	VERB
gs-3921	275	14	drug	drug	NOUN
gs-3921	275	15	absorption	absorption	NOUN
gs-3921	275	16	,	,	PUNCT
gs-3921	275	17	distribution	distribution	NOUN
gs-3921	275	18	,	,	PUNCT
gs-3921	275	19	metabolism	metabolism	NOUN
gs-3921	275	20	,	,	PUNCT
gs-3921	275	21	and	and	CCONJ
gs-3921	275	22	excretion	excretion	NOUN
gs-3921	275	23	(	(	PUNCT
gs-3921	275	24	adme	adme	NOUN
gs-3921	275	25	)	)	PUNCT
gs-3921	275	26	,	,	PUNCT
gs-3921	275	27	as	as	ADV
gs-3921	275	28	well	well	ADV
gs-3921	275	29	as	as	ADP
gs-3921	275	30	drug	drug	NOUN
gs-3921	275	31	targets	target	NOUN
gs-3921	275	32	and	and	CCONJ
gs-3921	275	33	downstream	downstream	ADJ
gs-3921	275	34	signaling	signal	VERB
gs-3921	275	35	pathways	pathway	NOUN
gs-3921	275	36	.	.	PUNCT
gs-3921	276	1	notably	notably	ADV
gs-3921	276	2	,	,	PUNCT
gs-3921	276	3	cytochrome	cytochrome	ADJ
gs-3921	276	4	p450	p450	NUM
gs-3921	276	5	enzyme	enzyme	NOUN
gs-3921	276	6	polymorphisms	polymorphism	NOUN
gs-3921	276	7	—	—	PUNCT
gs-3921	276	8	cyp2d6	cyp2d6	NOUN
gs-3921	276	9	,	,	PUNCT
gs-3921	276	10	cyp2c19	cyp2c19	PROPN
gs-3921	276	11	,	,	PUNCT
gs-3921	276	12	cyp2c9	cyp2c9	NOUN
gs-3921	276	13	,	,	PUNCT
gs-3921	276	14	and	and	CCONJ
gs-3921	276	15	georgian	georgian	ADJ
gs-3921	276	16	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	276	17	მეცნიერები	მეცნიერები	NOUN
gs-3921	276	18	ტ.	ტ.	VERB
gs-3921	276	19	7	7	NUM
gs-3921	276	20	n	n	PRON
gs-3921	276	21	3	3	NUM
gs-3921	276	22	,	,	PUNCT
gs-3921	276	23	2025	2025	NUM
gs-3921	276	24	234	234	NUM
gs-3921	276	25	cyp3a4/5	cyp3a4/5	NOUN
gs-3921	276	26	—	—	PUNCT
gs-3921	276	27	account	account	NOUN
gs-3921	276	28	for	for	ADP
gs-3921	276	29	substantial	substantial	ADJ
gs-3921	276	30	variability	variability	NOUN
gs-3921	276	31	in	in	ADP
gs-3921	276	32	the	the	DET
gs-3921	276	33	metabolism	metabolism	NOUN
gs-3921	276	34	of	of	ADP
gs-3921	276	35	widely	widely	ADV
gs-3921	276	36	prescribed	prescribe	VERB
gs-3921	276	37	medications	medication	NOUN
gs-3921	276	38	including	include	VERB
gs-3921	276	39	antidepressants	antidepressant	NOUN
gs-3921	276	40	,	,	PUNCT
gs-3921	276	41	antiplatelets	antiplatelet	NOUN
gs-3921	276	42	,	,	PUNCT
gs-3921	276	43	anticoagulants	anticoagulant	NOUN
gs-3921	276	44	,	,	PUNCT
gs-3921	276	45	and	and	CCONJ
gs-3921	276	46	chemotherapeutic	chemotherapeutic	ADJ
gs-3921	276	47	agents	agent	NOUN
gs-3921	276	48	.	.	PUNCT
gs-3921	277	1	extensive	extensive	ADJ
gs-3921	277	2	studies	study	NOUN
gs-3921	277	3	have	have	AUX
gs-3921	277	4	established	establish	VERB
gs-3921	277	5	that	that	PRON
gs-3921	277	6	poor	poor	ADJ
gs-3921	277	7	metabolizer	metabolizer	NOUN
gs-3921	277	8	phenotypes	phenotype	NOUN
gs-3921	277	9	often	often	ADV
gs-3921	277	10	exhibit	exhibit	VERB
gs-3921	277	11	elevated	elevated	ADJ
gs-3921	277	12	plasma	plasma	NOUN
gs-3921	277	13	drug	drug	NOUN
gs-3921	277	14	concentrations	concentration	NOUN
gs-3921	277	15	,	,	PUNCT
gs-3921	277	16	predisposing	predispose	VERB
gs-3921	277	17	patients	patient	NOUN
gs-3921	277	18	to	to	PART
gs-3921	277	19	dose	dose	VERB
gs-3921	277	20	-	-	PUNCT
gs-3921	277	21	dependent	dependent	ADJ
gs-3921	277	22	toxicities	toxicity	NOUN
gs-3921	277	23	,	,	PUNCT
gs-3921	277	24	whereas	whereas	SCONJ
gs-3921	277	25	ultra	ultra	ADJ
gs-3921	277	26	-	-	ADJ
gs-3921	277	27	rapid	rapid	ADJ
gs-3921	277	28	metabolizers	metabolizer	NOUN
gs-3921	277	29	risk	risk	VERB
gs-3921	277	30	therapeutic	therapeutic	ADJ
gs-3921	277	31	failure	failure	NOUN
gs-3921	277	32	.	.	PUNCT
gs-3921	278	1	beyond	beyond	ADP
gs-3921	278	2	metabolic	metabolic	NOUN
gs-3921	278	3	enzymes	enzyme	NOUN
gs-3921	278	4	,	,	PUNCT
gs-3921	278	5	the	the	DET
gs-3921	278	6	human	human	ADJ
gs-3921	278	7	leukocyte	leukocyte	NOUN
gs-3921	278	8	antigen	antigen	NOUN
gs-3921	278	9	(	(	PUNCT
gs-3921	278	10	hla	hla	NOUN
gs-3921	278	11	)	)	PUNCT
gs-3921	278	12	system	system	NOUN
gs-3921	278	13	has	have	AUX
gs-3921	278	14	emerged	emerge	VERB
gs-3921	278	15	as	as	ADP
gs-3921	278	16	a	a	DET
gs-3921	278	17	critical	critical	ADJ
gs-3921	278	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	278	19	locus	locus	NOUN
gs-3921	278	20	associated	associate	VERB
gs-3921	278	21	with	with	ADP
gs-3921	278	22	severe	severe	ADJ
gs-3921	278	23	hypersensitivity	hypersensitivity	NOUN
gs-3921	278	24	reactions	reaction	NOUN
gs-3921	278	25	.	.	PUNCT
gs-3921	279	1	for	for	ADP
gs-3921	279	2	example	example	NOUN
gs-3921	279	3	,	,	PUNCT
gs-3921	279	4	the	the	DET
gs-3921	279	5	association	association	NOUN
gs-3921	279	6	of	of	ADP
gs-3921	279	7	hla	hla	PROPN
gs-3921	279	8	-	-	PUNCT
gs-3921	279	9	b15:02	b15:02	PROPN
gs-3921	279	10	with	with	ADP
gs-3921	279	11	carbamazepine	carbamazepine	NOUN
gs-3921	279	12	-	-	PUNCT
gs-3921	279	13	induced	induce	VERB
gs-3921	279	14	stevens	stevens	PROPN
gs-3921	279	15	-	-	PUNCT
gs-3921	279	16	johnson	johnson	PROPN
gs-3921	279	17	syndrome	syndrome	PROPN
gs-3921	279	18	and	and	CCONJ
gs-3921	279	19	toxic	toxic	ADJ
gs-3921	279	20	epidermal	epidermal	ADJ
gs-3921	279	21	necrolysis	necrolysis	NOUN
gs-3921	279	22	has	have	AUX
gs-3921	279	23	precipitated	precipitate	VERB
gs-3921	279	24	region	region	NOUN
gs-3921	279	25	-	-	PUNCT
gs-3921	279	26	specific	specific	ADJ
gs-3921	279	27	screening	screening	NOUN
gs-3921	279	28	protocols	protocol	NOUN
gs-3921	279	29	,	,	PUNCT
gs-3921	279	30	notably	notably	ADV
gs-3921	279	31	in	in	ADP
gs-3921	279	32	southeast	southeast	ADJ
gs-3921	279	33	asian	asian	ADJ
gs-3921	279	34	populations	population	NOUN
gs-3921	279	35	.	.	PUNCT
gs-3921	280	1	similarly	similarly	ADV
gs-3921	280	2	,	,	PUNCT
gs-3921	280	3	hla	hla	PROPN
gs-3921	280	4	-	-	PUNCT
gs-3921	280	5	b57:01	b57:01	PROPN
gs-3921	280	6	screening	screening	NOUN
gs-3921	280	7	prior	prior	ADV
gs-3921	280	8	to	to	ADP
gs-3921	280	9	abacavir	abacavir	PROPN
gs-3921	280	10	initiation	initiation	NOUN
gs-3921	280	11	exemplifies	exemplify	VERB
gs-3921	280	12	a	a	DET
gs-3921	280	13	successful	successful	ADJ
gs-3921	280	14	implementation	implementation	NOUN
gs-3921	280	15	of	of	ADP
gs-3921	280	16	genotypeguided	genotypeguided	ADJ
gs-3921	280	17	therapy	therapy	NOUN
gs-3921	280	18	,	,	PUNCT
gs-3921	280	19	drastically	drastically	ADV
gs-3921	280	20	reducing	reduce	VERB
gs-3921	280	21	hypersensitivity	hypersensitivity	NOUN
gs-3921	280	22	incidence	incidence	NOUN
gs-3921	280	23	.	.	PUNCT
gs-3921	281	1	the	the	DET
gs-3921	281	2	elucidation	elucidation	NOUN
gs-3921	281	3	of	of	ADP
gs-3921	281	4	these	these	DET
gs-3921	281	5	allele	allele	NOUN
gs-3921	281	6	-	-	PUNCT
gs-3921	281	7	specific	specific	ADJ
gs-3921	281	8	risks	risk	NOUN
gs-3921	281	9	highlights	highlight	VERB
gs-3921	281	10	the	the	DET
gs-3921	281	11	necessity	necessity	NOUN
gs-3921	281	12	for	for	ADP
gs-3921	281	13	population	population	NOUN
gs-3921	281	14	-	-	PUNCT
gs-3921	281	15	tailored	tailor	VERB
gs-3921	281	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	281	17	screening	screening	NOUN
gs-3921	281	18	programs	program	NOUN
gs-3921	281	19	,	,	PUNCT
gs-3921	281	20	given	give	VERB
gs-3921	281	21	the	the	DET
gs-3921	281	22	marked	mark	VERB
gs-3921	281	23	interethnic	interethnic	ADJ
gs-3921	281	24	variability	variability	NOUN
gs-3921	281	25	in	in	ADP
gs-3921	281	26	allele	allele	NOUN
gs-3921	281	27	frequencies	frequency	NOUN
gs-3921	281	28	.	.	PUNCT
gs-3921	282	1	pharmacodynamic	pharmacodynamic	ADJ
gs-3921	282	2	gene	gene	NOUN
gs-3921	282	3	variants	variant	NOUN
gs-3921	282	4	affecting	affect	VERB
gs-3921	282	5	drug	drug	NOUN
gs-3921	282	6	targets	target	NOUN
gs-3921	282	7	also	also	ADV
gs-3921	282	8	contribute	contribute	VERB
gs-3921	282	9	to	to	ADP
gs-3921	282	10	adr	adr	PROPN
gs-3921	282	11	susceptibility	susceptibility	PROPN
gs-3921	282	12	.	.	PUNCT
gs-3921	283	1	variants	variant	NOUN
gs-3921	283	2	in	in	ADP
gs-3921	283	3	vkorc1	vkorc1	PROPN
gs-3921	283	4	and	and	CCONJ
gs-3921	283	5	cyp2c9	cyp2c9	NOUN
gs-3921	283	6	influence	influence	NOUN
gs-3921	283	7	warfarin	warfarin	NOUN
gs-3921	283	8	sensitivity	sensitivity	NOUN
gs-3921	283	9	and	and	CCONJ
gs-3921	283	10	bleeding	bleed	VERB
gs-3921	283	11	risk	risk	NOUN
gs-3921	283	12	,	,	PUNCT
gs-3921	283	13	necessitating	necessitate	VERB
gs-3921	283	14	genotype	genotype	NOUN
gs-3921	283	15	-	-	PUNCT
gs-3921	283	16	guided	guide	VERB
gs-3921	283	17	dose	dose	NOUN
gs-3921	283	18	individualization	individualization	NOUN
gs-3921	283	19	protocols	protocol	NOUN
gs-3921	283	20	.	.	PUNCT
gs-3921	284	1	likewise	likewise	ADV
gs-3921	284	2	,	,	PUNCT
gs-3921	284	3	polymorphisms	polymorphism	NOUN
gs-3921	284	4	in	in	ADP
gs-3921	284	5	the	the	DET
gs-3921	284	6	dopamine	dopamine	NOUN
gs-3921	284	7	receptor	receptor	NOUN
gs-3921	284	8	gene	gene	NOUN
gs-3921	284	9	drd2	drd2	NOUN
gs-3921	284	10	and	and	CCONJ
gs-3921	284	11	serotonin	serotonin	VERB
gs-3921	284	12	transporter	transporter	NOUN
gs-3921	284	13	gene	gene	NOUN
gs-3921	284	14	slc6a4	slc6a4	NOUN
gs-3921	284	15	affect	affect	VERB
gs-3921	284	16	psychotropic	psychotropic	ADJ
gs-3921	284	17	drug	drug	NOUN
gs-3921	284	18	efficacy	efficacy	NOUN
gs-3921	284	19	and	and	CCONJ
gs-3921	284	20	tolerability	tolerability	NOUN
gs-3921	284	21	.	.	PUNCT
gs-3921	285	1	the	the	DET
gs-3921	285	2	integration	integration	NOUN
gs-3921	285	3	of	of	ADP
gs-3921	285	4	such	such	ADJ
gs-3921	285	5	pharmacodynamic	pharmacodynamic	ADJ
gs-3921	285	6	markers	marker	NOUN
gs-3921	285	7	into	into	ADP
gs-3921	285	8	clinical	clinical	ADJ
gs-3921	285	9	decision	decision	NOUN
gs-3921	285	10	-	-	PUNCT
gs-3921	285	11	making	making	NOUN
gs-3921	285	12	remains	remain	VERB
gs-3921	285	13	an	an	DET
gs-3921	285	14	active	active	ADJ
gs-3921	285	15	area	area	NOUN
gs-3921	285	16	of	of	ADP
gs-3921	285	17	research	research	NOUN
gs-3921	285	18	,	,	PUNCT
gs-3921	285	19	with	with	ADP
gs-3921	285	20	emerging	emerge	VERB
gs-3921	285	21	evidence	evidence	NOUN
gs-3921	285	22	supporting	support	VERB
gs-3921	285	23	their	their	PRON
gs-3921	285	24	utility	utility	NOUN
gs-3921	285	25	in	in	ADP
gs-3921	285	26	refining	refine	VERB
gs-3921	285	27	therapeutic	therapeutic	ADJ
gs-3921	285	28	precision	precision	NOUN
gs-3921	285	29	.	.	PUNCT
gs-3921	286	1	clinical	clinical	ADJ
gs-3921	286	2	implementation	implementation	NOUN
gs-3921	286	3	and	and	CCONJ
gs-3921	286	4	integration	integration	NOUN
gs-3921	286	5	challenges	challenge	NOUN
gs-3921	286	6	while	while	SCONJ
gs-3921	286	7	the	the	DET
gs-3921	286	8	scientific	scientific	ADJ
gs-3921	286	9	evidence	evidence	NOUN
gs-3921	286	10	underpinning	underpin	VERB
gs-3921	286	11	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	286	12	is	be	AUX
gs-3921	286	13	robust	robust	ADJ
gs-3921	286	14	,	,	PUNCT
gs-3921	286	15	its	its	PRON
gs-3921	286	16	translation	translation	NOUN
gs-3921	286	17	into	into	ADP
gs-3921	286	18	routine	routine	ADJ
gs-3921	286	19	clinical	clinical	ADJ
gs-3921	286	20	practice	practice	NOUN
gs-3921	286	21	is	be	AUX
gs-3921	286	22	impeded	impede	VERB
gs-3921	286	23	by	by	ADP
gs-3921	286	24	multifactorial	multifactorial	ADJ
gs-3921	286	25	challenges	challenge	NOUN
gs-3921	286	26	.	.	PUNCT
gs-3921	287	1	foremost	foremost	ADV
gs-3921	287	2	is	be	AUX
gs-3921	287	3	the	the	DET
gs-3921	287	4	variable	variable	ADJ
gs-3921	287	5	clinician	clinician	NOUN
gs-3921	287	6	familiarity	familiarity	NOUN
gs-3921	287	7	and	and	CCONJ
gs-3921	287	8	confidence	confidence	NOUN
gs-3921	287	9	in	in	ADP
gs-3921	287	10	interpreting	interpret	VERB
gs-3921	287	11	and	and	CCONJ
gs-3921	287	12	applying	apply	VERB
gs-3921	287	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	287	14	data	datum	NOUN
gs-3921	287	15	.	.	PUNCT
gs-3921	288	1	surveys	survey	NOUN
gs-3921	288	2	across	across	ADP
gs-3921	288	3	diverse	diverse	ADJ
gs-3921	288	4	healthcare	healthcare	NOUN
gs-3921	288	5	settings	setting	NOUN
gs-3921	288	6	reveal	reveal	VERB
gs-3921	288	7	knowledge	knowledge	NOUN
gs-3921	288	8	gaps	gap	NOUN
gs-3921	288	9	and	and	CCONJ
gs-3921	288	10	uncertainty	uncertainty	NOUN
gs-3921	288	11	,	,	PUNCT
gs-3921	288	12	compounded	compound	VERB
gs-3921	288	13	by	by	ADP
gs-3921	288	14	the	the	DET
gs-3921	288	15	lack	lack	NOUN
gs-3921	288	16	of	of	ADP
gs-3921	288	17	standardized	standardized	ADJ
gs-3921	288	18	educational	educational	ADJ
gs-3921	288	19	curricula	curricula	NOUN
gs-3921	288	20	and	and	CCONJ
gs-3921	288	21	training	training	NOUN
gs-3921	288	22	.	.	PUNCT
gs-3921	289	1	this	this	DET
gs-3921	289	2	deficit	deficit	NOUN
gs-3921	289	3	impairs	impair	VERB
gs-3921	289	4	effective	effective	ADJ
gs-3921	289	5	patient	patient	NOUN
gs-3921	289	6	counseling	counseling	NOUN
gs-3921	289	7	and	and	CCONJ
gs-3921	289	8	limits	limit	VERB
gs-3921	289	9	the	the	DET
gs-3921	289	10	clinical	clinical	ADJ
gs-3921	289	11	utility	utility	NOUN
gs-3921	289	12	of	of	ADP
gs-3921	289	13	genetic	genetic	ADJ
gs-3921	289	14	testing	testing	NOUN
gs-3921	289	15	.	.	PUNCT
gs-3921	290	1	economic	economic	ADJ
gs-3921	290	2	constraints	constraint	NOUN
gs-3921	290	3	further	far	ADV
gs-3921	290	4	restrict	restrict	VERB
gs-3921	290	5	implementation	implementation	NOUN
gs-3921	290	6	.	.	PUNCT
gs-3921	291	1	the	the	DET
gs-3921	291	2	costs	cost	NOUN
gs-3921	291	3	of	of	ADP
gs-3921	291	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	291	5	testing	testing	NOUN
gs-3921	291	6	,	,	PUNCT
gs-3921	291	7	although	although	SCONJ
gs-3921	291	8	decreasing	decrease	VERB
gs-3921	291	9	,	,	PUNCT
gs-3921	291	10	remain	remain	VERB
gs-3921	291	11	prohibitive	prohibitive	ADJ
gs-3921	291	12	in	in	ADP
gs-3921	291	13	many	many	ADJ
gs-3921	291	14	healthcare	healthcare	NOUN
gs-3921	291	15	systems	system	NOUN
gs-3921	291	16	,	,	PUNCT
gs-3921	291	17	particularly	particularly	ADV
gs-3921	291	18	where	where	SCONJ
gs-3921	291	19	reimbursement	reimbursement	NOUN
gs-3921	291	20	frameworks	framework	NOUN
gs-3921	291	21	are	be	AUX
gs-3921	291	22	underdeveloped	underdeveloped	ADJ
gs-3921	291	23	or	or	CCONJ
gs-3921	291	24	absent	absent	ADJ
gs-3921	291	25	.	.	PUNCT
gs-3921	292	1	the	the	DET
gs-3921	292	2	lack	lack	NOUN
gs-3921	292	3	of	of	ADP
gs-3921	292	4	universally	universally	ADV
gs-3921	292	5	accepted	accept	VERB
gs-3921	292	6	cost	cost	NOUN
gs-3921	292	7	-	-	PUNCT
gs-3921	292	8	effectiveness	effectiveness	NOUN
gs-3921	292	9	data	datum	NOUN
gs-3921	292	10	engenders	engender	NOUN
gs-3921	292	11	hesitancy	hesitancy	NOUN
gs-3921	292	12	among	among	ADP
gs-3921	292	13	payers	payer	NOUN
gs-3921	292	14	and	and	CCONJ
gs-3921	292	15	policymakers	policymaker	NOUN
gs-3921	292	16	.	.	PUNCT
gs-3921	293	1	notably	notably	ADV
gs-3921	293	2	,	,	PUNCT
gs-3921	293	3	economic	economic	ADJ
gs-3921	293	4	evaluations	evaluation	NOUN
gs-3921	293	5	demonstrate	demonstrate	VERB
gs-3921	293	6	that	that	SCONJ
gs-3921	293	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	293	8	testing	testing	NOUN
gs-3921	293	9	can	can	AUX
gs-3921	293	10	be	be	AUX
gs-3921	293	11	costsaving	costsave	VERB
gs-3921	293	12	in	in	ADP
gs-3921	293	13	conditions	condition	NOUN
gs-3921	293	14	with	with	ADP
gs-3921	293	15	high	high	ADJ
gs-3921	293	16	adr	adr	PROPN
gs-3921	293	17	incidence	incidence	NOUN
gs-3921	293	18	or	or	CCONJ
gs-3921	293	19	severe	severe	ADJ
gs-3921	293	20	toxicity	toxicity	NOUN
gs-3921	293	21	risk	risk	NOUN
gs-3921	293	22	,	,	PUNCT
gs-3921	293	23	such	such	ADJ
gs-3921	293	24	as	as	ADP
gs-3921	293	25	anticoagulation	anticoagulation	NOUN
gs-3921	293	26	and	and	CCONJ
gs-3921	293	27	oncology	oncology	NOUN
gs-3921	293	28	,	,	PUNCT
gs-3921	293	29	yet	yet	CCONJ
gs-3921	293	30	broad	broad	ADJ
gs-3921	293	31	application	application	NOUN
gs-3921	293	32	requires	require	VERB
gs-3921	293	33	more	more	ADV
gs-3921	293	34	comprehensive	comprehensive	ADJ
gs-3921	293	35	health	health	NOUN
gs-3921	293	36	economic	economic	ADJ
gs-3921	293	37	analyses	analysis	NOUN
gs-3921	293	38	encompassing	encompass	VERB
gs-3921	293	39	diverse	diverse	ADJ
gs-3921	293	40	clinical	clinical	ADJ
gs-3921	293	41	scenarios	scenario	NOUN
gs-3921	293	42	and	and	CCONJ
gs-3921	293	43	populations	population	NOUN
gs-3921	293	44	.	.	PUNCT
gs-3921	294	1	systemic	systemic	ADJ
gs-3921	294	2	infrastructural	infrastructural	ADJ
gs-3921	294	3	deficits	deficit	NOUN
gs-3921	294	4	also	also	ADV
gs-3921	294	5	hinder	hinder	VERB
gs-3921	294	6	implementation	implementation	NOUN
gs-3921	294	7	.	.	PUNCT
gs-3921	295	1	the	the	DET
gs-3921	295	2	integration	integration	NOUN
gs-3921	295	3	of	of	ADP
gs-3921	295	4	genetic	genetic	ADJ
gs-3921	295	5	data	datum	NOUN
gs-3921	295	6	into	into	ADP
gs-3921	295	7	electronic	electronic	ADJ
gs-3921	295	8	health	health	NOUN
gs-3921	295	9	records	record	NOUN
gs-3921	295	10	(	(	PUNCT
gs-3921	295	11	ehrs	ehrs	INTJ
gs-3921	295	12	)	)	PUNCT
gs-3921	295	13	and	and	CCONJ
gs-3921	295	14	clinical	clinical	ADJ
gs-3921	295	15	decision	decision	NOUN
gs-3921	295	16	support	support	NOUN
gs-3921	295	17	systems	system	NOUN
gs-3921	295	18	georgian	georgian	PROPN
gs-3921	295	19	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	295	20	მეცნიერები	მეცნიერები	NOUN
gs-3921	295	21	ტ.	ტ.	VERB
gs-3921	295	22	7	7	NUM
gs-3921	295	23	n	n	PRON
gs-3921	295	24	3	3	NUM
gs-3921	295	25	,	,	PUNCT
gs-3921	295	26	2025	2025	NUM
gs-3921	295	27	235	235	NUM
gs-3921	295	28	(	(	PUNCT
gs-3921	295	29	cdss	cdss	NOUN
gs-3921	295	30	)	)	PUNCT
gs-3921	295	31	is	be	AUX
gs-3921	295	32	essential	essential	ADJ
gs-3921	295	33	for	for	ADP
gs-3921	295	34	real	real	ADJ
gs-3921	295	35	-	-	PUNCT
gs-3921	295	36	time	time	NOUN
gs-3921	295	37	,	,	PUNCT
gs-3921	295	38	point	point	NOUN
gs-3921	295	39	-	-	PUNCT
gs-3921	295	40	of	of	ADP
gs-3921	295	41	-	-	PUNCT
gs-3921	295	42	care	care	NOUN
gs-3921	295	43	decision	decision	NOUN
gs-3921	295	44	-	-	PUNCT
gs-3921	295	45	making	making	NOUN
gs-3921	295	46	but	but	CCONJ
gs-3921	295	47	faces	face	VERB
gs-3921	295	48	technological	technological	ADJ
gs-3921	295	49	,	,	PUNCT
gs-3921	295	50	interoperability	interoperability	NOUN
gs-3921	295	51	,	,	PUNCT
gs-3921	295	52	and	and	CCONJ
gs-3921	295	53	workflow	workflow	NOUN
gs-3921	295	54	integration	integration	NOUN
gs-3921	295	55	challenges	challenge	NOUN
gs-3921	295	56	.	.	PUNCT
gs-3921	296	1	many	many	ADJ
gs-3921	296	2	institutions	institution	NOUN
gs-3921	296	3	lack	lack	VERB
gs-3921	296	4	the	the	DET
gs-3921	296	5	informatics	informatic	NOUN
gs-3921	296	6	infrastructure	infrastructure	NOUN
gs-3921	296	7	or	or	CCONJ
gs-3921	296	8	standardized	standardized	ADJ
gs-3921	296	9	protocols	protocol	NOUN
gs-3921	296	10	to	to	PART
gs-3921	296	11	incorporate	incorporate	VERB
gs-3921	296	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	296	13	results	result	NOUN
gs-3921	296	14	meaningfully	meaningfully	ADV
gs-3921	296	15	into	into	ADP
gs-3921	296	16	prescribing	prescribing	NOUN
gs-3921	296	17	practices	practice	NOUN
gs-3921	296	18	.	.	PUNCT
gs-3921	297	1	alert	alert	ADJ
gs-3921	297	2	fatigue	fatigue	NOUN
gs-3921	297	3	and	and	CCONJ
gs-3921	297	4	poor	poor	ADJ
gs-3921	297	5	user	user	NOUN
gs-3921	297	6	interface	interface	NOUN
gs-3921	297	7	design	design	NOUN
gs-3921	297	8	further	further	ADJ
gs-3921	297	9	limit	limit	NOUN
gs-3921	297	10	clinician	clinician	ADJ
gs-3921	297	11	engagement	engagement	NOUN
gs-3921	297	12	with	with	ADP
gs-3921	297	13	cdss	cdss	PROPN
gs-3921	297	14	.	.	PUNCT
gs-3921	298	1	patient	patient	NOUN
gs-3921	298	2	-	-	PUNCT
gs-3921	298	3	centered	center	VERB
gs-3921	298	4	approaches	approach	NOUN
gs-3921	298	5	are	be	AUX
gs-3921	298	6	critical	critical	ADJ
gs-3921	298	7	to	to	ADP
gs-3921	298	8	overcoming	overcome	VERB
gs-3921	298	9	these	these	DET
gs-3921	298	10	barriers	barrier	NOUN
gs-3921	298	11	.	.	PUNCT
gs-3921	299	1	shared	share	VERB
gs-3921	299	2	decision	decision	NOUN
gs-3921	299	3	-	-	PUNCT
gs-3921	299	4	making	make	VERB
gs-3921	299	5	models	model	NOUN
gs-3921	299	6	emphasize	emphasize	VERB
gs-3921	299	7	the	the	DET
gs-3921	299	8	need	need	NOUN
gs-3921	299	9	for	for	ADP
gs-3921	299	10	clear	clear	ADJ
gs-3921	299	11	communication	communication	NOUN
gs-3921	299	12	,	,	PUNCT
gs-3921	299	13	cultural	cultural	ADJ
gs-3921	299	14	sensitivity	sensitivity	NOUN
gs-3921	299	15	,	,	PUNCT
gs-3921	299	16	and	and	CCONJ
gs-3921	299	17	incorporation	incorporation	NOUN
gs-3921	299	18	of	of	ADP
gs-3921	299	19	patient	patient	ADJ
gs-3921	299	20	values	value	NOUN
gs-3921	299	21	and	and	CCONJ
gs-3921	299	22	preferences	preference	NOUN
gs-3921	299	23	.	.	PUNCT
gs-3921	300	1	studies	study	NOUN
gs-3921	300	2	demonstrate	demonstrate	VERB
gs-3921	300	3	that	that	SCONJ
gs-3921	300	4	patients	patient	NOUN
gs-3921	300	5	engaged	engage	VERB
gs-3921	300	6	in	in	ADP
gs-3921	300	7	discussions	discussion	NOUN
gs-3921	300	8	about	about	ADP
gs-3921	300	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	300	10	testing	testing	NOUN
gs-3921	300	11	exhibit	exhibit	VERB
gs-3921	300	12	greater	great	ADJ
gs-3921	300	13	acceptance	acceptance	NOUN
gs-3921	300	14	,	,	PUNCT
gs-3921	300	15	adherence	adherence	NOUN
gs-3921	300	16	,	,	PUNCT
gs-3921	300	17	and	and	CCONJ
gs-3921	300	18	satisfaction	satisfaction	NOUN
gs-3921	300	19	.	.	PUNCT
gs-3921	301	1	nevertheless	nevertheless	ADV
gs-3921	301	2	,	,	PUNCT
gs-3921	301	3	disparities	disparity	NOUN
gs-3921	301	4	in	in	ADP
gs-3921	301	5	health	health	NOUN
gs-3921	301	6	literacy	literacy	NOUN
gs-3921	301	7	,	,	PUNCT
gs-3921	301	8	cultural	cultural	ADJ
gs-3921	301	9	beliefs	belief	NOUN
gs-3921	301	10	,	,	PUNCT
gs-3921	301	11	and	and	CCONJ
gs-3921	301	12	access	access	NOUN
gs-3921	301	13	to	to	ADP
gs-3921	301	14	genetic	genetic	ADJ
gs-3921	301	15	counseling	counseling	NOUN
gs-3921	301	16	services	service	NOUN
gs-3921	301	17	may	may	AUX
gs-3921	301	18	limit	limit	VERB
gs-3921	301	19	equitable	equitable	ADJ
gs-3921	301	20	patient	patient	ADJ
gs-3921	301	21	participation	participation	NOUN
gs-3921	301	22	.	.	PUNCT
gs-3921	302	1	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	302	2	evolution	evolution	NOUN
gs-3921	302	3	in	in	ADP
gs-3921	302	4	the	the	DET
gs-3921	302	5	genomic	genomic	ADJ
gs-3921	302	6	era	era	NOUN
gs-3921	302	7	traditional	traditional	ADJ
gs-3921	302	8	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	302	9	systems	system	NOUN
gs-3921	302	10	rely	rely	VERB
gs-3921	302	11	predominantly	predominantly	ADV
gs-3921	302	12	on	on	ADP
gs-3921	302	13	spontaneous	spontaneous	ADJ
gs-3921	302	14	adverse	adverse	ADJ
gs-3921	302	15	event	event	NOUN
gs-3921	302	16	reporting	reporting	NOUN
gs-3921	302	17	,	,	PUNCT
gs-3921	302	18	which	which	PRON
gs-3921	302	19	is	be	AUX
gs-3921	302	20	subject	subject	ADJ
gs-3921	302	21	to	to	ADP
gs-3921	302	22	underreporting	underreporting	NOUN
gs-3921	302	23	,	,	PUNCT
gs-3921	302	24	bias	bias	NOUN
gs-3921	302	25	,	,	PUNCT
gs-3921	302	26	and	and	CCONJ
gs-3921	302	27	delayed	delay	VERB
gs-3921	302	28	detection	detection	NOUN
gs-3921	302	29	of	of	ADP
gs-3921	302	30	safety	safety	NOUN
gs-3921	302	31	signals	signal	NOUN
gs-3921	302	32	.	.	PUNCT
gs-3921	303	1	the	the	DET
gs-3921	303	2	integration	integration	NOUN
gs-3921	303	3	of	of	ADP
gs-3921	303	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	303	5	data	datum	NOUN
gs-3921	303	6	into	into	ADP
gs-3921	303	7	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	303	8	frameworks	framework	NOUN
gs-3921	303	9	enhances	enhance	VERB
gs-3921	303	10	the	the	DET
gs-3921	303	11	granularity	granularity	NOUN
gs-3921	303	12	and	and	CCONJ
gs-3921	303	13	specificity	specificity	NOUN
gs-3921	303	14	of	of	ADP
gs-3921	303	15	adverse	adverse	ADJ
gs-3921	303	16	event	event	NOUN
gs-3921	303	17	detection	detection	NOUN
gs-3921	303	18	.	.	PUNCT
gs-3921	304	1	by	by	ADP
gs-3921	304	2	stratifying	stratify	VERB
gs-3921	304	3	risk	risk	NOUN
gs-3921	304	4	based	base	VERB
gs-3921	304	5	on	on	ADP
gs-3921	304	6	genetic	genetic	ADJ
gs-3921	304	7	predisposition	predisposition	NOUN
gs-3921	304	8	,	,	PUNCT
gs-3921	304	9	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	304	10	programs	program	NOUN
gs-3921	304	11	can	can	AUX
gs-3921	304	12	identify	identify	VERB
gs-3921	304	13	subpopulations	subpopulation	NOUN
gs-3921	304	14	vulnerable	vulnerable	ADJ
gs-3921	304	15	to	to	ADP
gs-3921	304	16	particular	particular	ADJ
gs-3921	304	17	toxicities	toxicity	NOUN
gs-3921	304	18	,	,	PUNCT
gs-3921	304	19	facilitating	facilitate	VERB
gs-3921	304	20	targeted	target	VERB
gs-3921	304	21	monitoring	monitoring	NOUN
gs-3921	304	22	and	and	CCONJ
gs-3921	304	23	risk	risk	NOUN
gs-3921	304	24	mitigation	mitigation	NOUN
gs-3921	304	25	.	.	PUNCT
gs-3921	305	1	advanced	advanced	ADJ
gs-3921	305	2	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	305	3	approaches	approach	NOUN
gs-3921	305	4	employ	employ	VERB
gs-3921	305	5	real	real	ADJ
gs-3921	305	6	-	-	PUNCT
gs-3921	305	7	world	world	NOUN
gs-3921	305	8	data	datum	NOUN
gs-3921	305	9	sources	source	NOUN
gs-3921	305	10	including	include	VERB
gs-3921	305	11	electronic	electronic	ADJ
gs-3921	305	12	health	health	NOUN
gs-3921	305	13	records	record	NOUN
gs-3921	305	14	,	,	PUNCT
gs-3921	305	15	claims	claim	VERB
gs-3921	305	16	databases	database	NOUN
gs-3921	305	17	,	,	PUNCT
gs-3921	305	18	and	and	CCONJ
gs-3921	305	19	patient	patient	ADJ
gs-3921	305	20	registries	registry	NOUN
gs-3921	305	21	,	,	PUNCT
gs-3921	305	22	often	often	ADV
gs-3921	305	23	enhanced	enhance	VERB
gs-3921	305	24	by	by	ADP
gs-3921	305	25	natural	natural	ADJ
gs-3921	305	26	language	language	NOUN
gs-3921	305	27	processing	processing	NOUN
gs-3921	305	28	and	and	CCONJ
gs-3921	305	29	machine	machine	NOUN
gs-3921	305	30	learning	learn	VERB
gs-3921	305	31	algorithms	algorithm	NOUN
gs-3921	305	32	.	.	PUNCT
gs-3921	306	1	these	these	DET
gs-3921	306	2	active	active	ADJ
gs-3921	306	3	surveillance	surveillance	NOUN
gs-3921	306	4	systems	system	NOUN
gs-3921	306	5	enable	enable	ADJ
gs-3921	306	6	near	near	ADP
gs-3921	306	7	real	real	ADJ
gs-3921	306	8	-	-	PUNCT
gs-3921	306	9	time	time	NOUN
gs-3921	306	10	detection	detection	NOUN
gs-3921	306	11	of	of	ADP
gs-3921	306	12	safety	safety	NOUN
gs-3921	306	13	signals	signal	NOUN
gs-3921	306	14	and	and	CCONJ
gs-3921	306	15	gene	gene	NOUN
gs-3921	306	16	-	-	PUNCT
gs-3921	306	17	drug	drug	NOUN
gs-3921	306	18	interaction	interaction	NOUN
gs-3921	306	19	profiling	profiling	NOUN
gs-3921	306	20	.	.	PUNCT
gs-3921	307	1	for	for	ADP
gs-3921	307	2	example	example	NOUN
gs-3921	307	3	,	,	PUNCT
gs-3921	307	4	the	the	DET
gs-3921	307	5	u.s	u.s	PROPN
gs-3921	307	6	.	.	PROPN
gs-3921	307	7	fda	fda	PROPN
gs-3921	307	8	’s	’s	PART
gs-3921	307	9	sentinel	sentinel	ADJ
gs-3921	307	10	initiative	initiative	NOUN
gs-3921	307	11	incorporates	incorporate	VERB
gs-3921	307	12	genetic	genetic	ADJ
gs-3921	307	13	data	datum	NOUN
gs-3921	307	14	to	to	PART
gs-3921	307	15	monitor	monitor	VERB
gs-3921	307	16	postmarketing	postmarkete	VERB
gs-3921	307	17	drug	drug	NOUN
gs-3921	307	18	safety	safety	NOUN
gs-3921	307	19	with	with	ADP
gs-3921	307	20	unprecedented	unprecedented	ADJ
gs-3921	307	21	scale	scale	NOUN
gs-3921	307	22	and	and	CCONJ
gs-3921	307	23	precision	precision	NOUN
gs-3921	307	24	.	.	PUNCT
gs-3921	308	1	despite	despite	SCONJ
gs-3921	308	2	these	these	DET
gs-3921	308	3	advances	advance	NOUN
gs-3921	308	4	,	,	PUNCT
gs-3921	308	5	challenges	challenge	NOUN
gs-3921	308	6	remain	remain	VERB
gs-3921	308	7	in	in	ADP
gs-3921	308	8	standardizing	standardize	VERB
gs-3921	308	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	308	10	data	datum	NOUN
gs-3921	308	11	collection	collection	NOUN
gs-3921	308	12	,	,	PUNCT
gs-3921	308	13	ensuring	ensure	VERB
gs-3921	308	14	data	datum	NOUN
gs-3921	308	15	quality	quality	NOUN
gs-3921	308	16	,	,	PUNCT
gs-3921	308	17	and	and	CCONJ
gs-3921	308	18	protecting	protect	VERB
gs-3921	308	19	patient	patient	ADJ
gs-3921	308	20	privacy	privacy	NOUN
gs-3921	308	21	.	.	PUNCT
gs-3921	309	1	polypharmacy	polypharmacy	NOUN
gs-3921	309	2	and	and	CCONJ
gs-3921	309	3	complex	complex	ADJ
gs-3921	309	4	interactions	interaction	NOUN
gs-3921	309	5	the	the	DET
gs-3921	309	6	increasing	increase	VERB
gs-3921	309	7	prevalence	prevalence	NOUN
gs-3921	309	8	of	of	ADP
gs-3921	309	9	polypharmacy	polypharmacy	NOUN
gs-3921	309	10	,	,	PUNCT
gs-3921	309	11	especially	especially	ADV
gs-3921	309	12	among	among	ADP
gs-3921	309	13	aging	age	VERB
gs-3921	309	14	populations	population	NOUN
gs-3921	309	15	with	with	ADP
gs-3921	309	16	multiple	multiple	ADJ
gs-3921	309	17	chronic	chronic	ADJ
gs-3921	309	18	conditions	condition	NOUN
gs-3921	309	19	,	,	PUNCT
gs-3921	309	20	magnifies	magnify	VERB
gs-3921	309	21	the	the	DET
gs-3921	309	22	complexity	complexity	NOUN
gs-3921	309	23	of	of	ADP
gs-3921	309	24	drug	drug	NOUN
gs-3921	309	25	therapy	therapy	NOUN
gs-3921	309	26	and	and	CCONJ
gs-3921	309	27	heightens	heighten	VERB
gs-3921	309	28	adverse	adverse	ADJ
gs-3921	309	29	effect	effect	NOUN
gs-3921	309	30	risks	risk	NOUN
gs-3921	309	31	.	.	PUNCT
gs-3921	310	1	polypharmacy	polypharmacy	NOUN
gs-3921	310	2	introduces	introduce	VERB
gs-3921	310	3	potential	potential	ADJ
gs-3921	310	4	drug	drug	NOUN
gs-3921	310	5	-	-	PUNCT
gs-3921	310	6	drug	drug	NOUN
gs-3921	310	7	interactions	interaction	NOUN
gs-3921	310	8	that	that	PRON
gs-3921	310	9	can	can	AUX
gs-3921	310	10	alter	alter	VERB
gs-3921	310	11	drug	drug	NOUN
gs-3921	310	12	metabolism	metabolism	NOUN
gs-3921	310	13	and	and	CCONJ
gs-3921	310	14	efficacy	efficacy	NOUN
gs-3921	310	15	,	,	PUNCT
gs-3921	310	16	complicating	complicate	VERB
gs-3921	310	17	clinical	clinical	ADJ
gs-3921	310	18	management	management	NOUN
gs-3921	310	19	.	.	PUNCT
gs-3921	311	1	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	311	2	provides	provide	VERB
gs-3921	311	3	a	a	DET
gs-3921	311	4	crucial	crucial	ADJ
gs-3921	311	5	tool	tool	NOUN
gs-3921	311	6	for	for	ADP
gs-3921	311	7	disentangling	disentangle	VERB
gs-3921	311	8	these	these	DET
gs-3921	311	9	interactions	interaction	NOUN
gs-3921	311	10	by	by	ADP
gs-3921	311	11	predicting	predict	VERB
gs-3921	311	12	individual	individual	ADJ
gs-3921	311	13	metabolic	metabolic	NOUN
gs-3921	311	14	capacity	capacity	NOUN
gs-3921	311	15	and	and	CCONJ
gs-3921	311	16	susceptibility	susceptibility	NOUN
gs-3921	311	17	to	to	ADP
gs-3921	311	18	interaction	interaction	NOUN
gs-3921	311	19	-	-	PUNCT
gs-3921	311	20	related	relate	VERB
gs-3921	311	21	toxicities	toxicity	NOUN
gs-3921	311	22	.	.	PUNCT
gs-3921	312	1	recent	recent	ADJ
gs-3921	312	2	research	research	NOUN
gs-3921	312	3	advocates	advocate	NOUN
gs-3921	312	4	for	for	ADP
gs-3921	312	5	integrated	integrate	VERB
gs-3921	312	6	clinical	clinical	ADJ
gs-3921	312	7	decision	decision	NOUN
gs-3921	312	8	support	support	NOUN
gs-3921	312	9	platforms	platform	NOUN
gs-3921	312	10	capable	capable	ADJ
gs-3921	312	11	of	of	ADP
gs-3921	312	12	synthesizing	synthesize	VERB
gs-3921	312	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	312	14	profiles	profile	NOUN
gs-3921	312	15	with	with	ADP
gs-3921	312	16	comprehensive	comprehensive	ADJ
gs-3921	312	17	medication	medication	NOUN
gs-3921	312	18	lists	list	NOUN
gs-3921	312	19	,	,	PUNCT
gs-3921	312	20	laboratory	laboratory	NOUN
gs-3921	312	21	data	datum	NOUN
gs-3921	312	22	,	,	PUNCT
gs-3921	312	23	and	and	CCONJ
gs-3921	312	24	clinical	clinical	ADJ
gs-3921	312	25	parameters	parameter	NOUN
gs-3921	312	26	to	to	PART
gs-3921	312	27	optimize	optimize	VERB
gs-3921	312	28	therapy	therapy	NOUN
gs-3921	312	29	.	.	PUNCT
gs-3921	313	1	pharmacists	pharmacist	NOUN
gs-3921	313	2	,	,	PUNCT
gs-3921	313	3	as	as	ADP
gs-3921	313	4	medication	medication	NOUN
gs-3921	313	5	experts	expert	NOUN
gs-3921	313	6	,	,	PUNCT
gs-3921	313	7	are	be	AUX
gs-3921	313	8	pivotal	pivotal	ADJ
gs-3921	313	9	in	in	ADP
gs-3921	313	10	implementing	implement	VERB
gs-3921	313	11	these	these	DET
gs-3921	313	12	approaches	approach	NOUN
gs-3921	313	13	through	through	ADP
gs-3921	313	14	medication	medication	NOUN
gs-3921	313	15	therapy	therapy	NOUN
gs-3921	313	16	management	management	NOUN
gs-3921	313	17	georgian	georgian	PROPN
gs-3921	313	18	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	313	19	მეცნიერები	მეცნიერები	NOUN
gs-3921	313	20	ტ.	ტ.	VERB
gs-3921	313	21	7	7	NUM
gs-3921	313	22	n	n	PRON
gs-3921	313	23	3	3	NUM
gs-3921	313	24	,	,	PUNCT
gs-3921	313	25	2025	2025	NUM
gs-3921	313	26	236	236	NUM
gs-3921	313	27	services	service	NOUN
gs-3921	313	28	that	that	PRON
gs-3921	313	29	incorporate	incorporate	VERB
gs-3921	313	30	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	313	31	considerations	consideration	NOUN
gs-3921	313	32	.	.	PUNCT
gs-3921	314	1	such	such	ADJ
gs-3921	314	2	multidisciplinary	multidisciplinary	ADJ
gs-3921	314	3	collaborations	collaboration	NOUN
gs-3921	314	4	improve	improve	VERB
gs-3921	314	5	therapeutic	therapeutic	ADJ
gs-3921	314	6	safety	safety	NOUN
gs-3921	314	7	and	and	CCONJ
gs-3921	314	8	patient	patient	ADJ
gs-3921	314	9	outcomes	outcome	NOUN
gs-3921	314	10	.	.	PUNCT
gs-3921	315	1	emerging	emerge	VERB
gs-3921	315	2	scientific	scientific	ADJ
gs-3921	315	3	frontiers	frontier	NOUN
gs-3921	315	4	:	:	PUNCT
gs-3921	315	5	multi	multi	ADJ
gs-3921	315	6	-	-	ADJ
gs-3921	315	7	omics	omic	NOUN
gs-3921	315	8	and	and	CCONJ
gs-3921	315	9	systems	system	NOUN
gs-3921	315	10	pharmacology	pharmacology	NOUN
gs-3921	315	11	beyond	beyond	ADP
gs-3921	315	12	single	single	ADJ
gs-3921	315	13	-	-	PUNCT
gs-3921	315	14	gene	gene	NOUN
gs-3921	315	15	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	315	16	,	,	PUNCT
gs-3921	315	17	multi	multi	ADJ
gs-3921	315	18	-	-	ADJ
gs-3921	315	19	omics	omic	NOUN
gs-3921	315	20	approaches	approach	VERB
gs-3921	315	21	encompassing	encompass	VERB
gs-3921	315	22	genomics	genomic	NOUN
gs-3921	315	23	,	,	PUNCT
gs-3921	315	24	transcriptomics	transcriptomic	NOUN
gs-3921	315	25	,	,	PUNCT
gs-3921	315	26	proteomics	proteomic	NOUN
gs-3921	315	27	,	,	PUNCT
gs-3921	315	28	metabolomics	metabolomic	NOUN
gs-3921	315	29	,	,	PUNCT
gs-3921	315	30	and	and	CCONJ
gs-3921	315	31	epigenomics	epigenomic	NOUN
gs-3921	315	32	provide	provide	VERB
gs-3921	315	33	a	a	DET
gs-3921	315	34	systemslevel	systemslevel	ADJ
gs-3921	315	35	understanding	understanding	NOUN
gs-3921	315	36	of	of	ADP
gs-3921	315	37	drug	drug	NOUN
gs-3921	315	38	response	response	NOUN
gs-3921	315	39	variability	variability	NOUN
gs-3921	315	40	.	.	PUNCT
gs-3921	316	1	epigenetic	epigenetic	ADJ
gs-3921	316	2	modifications	modification	NOUN
gs-3921	316	3	,	,	PUNCT
gs-3921	316	4	for	for	ADP
gs-3921	316	5	instance	instance	NOUN
gs-3921	316	6	,	,	PUNCT
gs-3921	316	7	dynamically	dynamically	ADV
gs-3921	316	8	regulate	regulate	VERB
gs-3921	316	9	gene	gene	NOUN
gs-3921	316	10	expression	expression	NOUN
gs-3921	316	11	influencing	influence	VERB
gs-3921	316	12	drug	drug	NOUN
gs-3921	316	13	metabolism	metabolism	NOUN
gs-3921	316	14	and	and	CCONJ
gs-3921	316	15	target	target	NOUN
gs-3921	316	16	sensitivity	sensitivity	NOUN
gs-3921	316	17	,	,	PUNCT
gs-3921	316	18	affected	affect	VERB
gs-3921	316	19	by	by	ADP
gs-3921	316	20	environmental	environmental	ADJ
gs-3921	316	21	exposures	exposure	NOUN
gs-3921	316	22	and	and	CCONJ
gs-3921	316	23	disease	disease	NOUN
gs-3921	316	24	states	state	NOUN
gs-3921	316	25	.	.	PUNCT
gs-3921	317	1	transcriptomic	transcriptomic	ADJ
gs-3921	317	2	profiling	profiling	NOUN
gs-3921	317	3	captures	capture	NOUN
gs-3921	317	4	changes	change	NOUN
gs-3921	317	5	in	in	ADP
gs-3921	317	6	gene	gene	NOUN
gs-3921	317	7	expression	expression	NOUN
gs-3921	317	8	induced	induce	VERB
gs-3921	317	9	by	by	ADP
gs-3921	317	10	drugs	drug	NOUN
gs-3921	317	11	or	or	CCONJ
gs-3921	317	12	pathophysiological	pathophysiological	ADJ
gs-3921	317	13	conditions	condition	NOUN
gs-3921	317	14	,	,	PUNCT
gs-3921	317	15	potentially	potentially	ADV
gs-3921	317	16	serving	serve	VERB
gs-3921	317	17	as	as	ADP
gs-3921	317	18	biomarkers	biomarker	NOUN
gs-3921	317	19	for	for	ADP
gs-3921	317	20	toxicity	toxicity	NOUN
gs-3921	317	21	or	or	CCONJ
gs-3921	317	22	efficacy	efficacy	NOUN
gs-3921	317	23	.	.	PUNCT
gs-3921	318	1	the	the	DET
gs-3921	318	2	integration	integration	NOUN
gs-3921	318	3	of	of	ADP
gs-3921	318	4	multi	multi	ADJ
gs-3921	318	5	-	-	ADJ
gs-3921	318	6	omic	omic	ADJ
gs-3921	318	7	data	datum	NOUN
gs-3921	318	8	with	with	ADP
gs-3921	318	9	clinical	clinical	ADJ
gs-3921	318	10	and	and	CCONJ
gs-3921	318	11	environmental	environmental	ADJ
gs-3921	318	12	factors	factor	NOUN
gs-3921	318	13	through	through	ADP
gs-3921	318	14	systems	system	NOUN
gs-3921	318	15	pharmacology	pharmacology	NOUN
gs-3921	318	16	models	model	NOUN
gs-3921	318	17	enables	enable	VERB
gs-3921	318	18	sophisticated	sophisticated	ADJ
gs-3921	318	19	predictions	prediction	NOUN
gs-3921	318	20	of	of	ADP
gs-3921	318	21	drug	drug	NOUN
gs-3921	318	22	response	response	NOUN
gs-3921	318	23	and	and	CCONJ
gs-3921	318	24	adverse	adverse	ADJ
gs-3921	318	25	events	event	NOUN
gs-3921	318	26	.	.	PUNCT
gs-3921	319	1	computational	computational	ADJ
gs-3921	319	2	models	model	NOUN
gs-3921	319	3	simulate	simulate	VERB
gs-3921	319	4	drug	drug	NOUN
gs-3921	319	5	-	-	PUNCT
gs-3921	319	6	target	target	NOUN
gs-3921	319	7	interactions	interaction	NOUN
gs-3921	319	8	,	,	PUNCT
gs-3921	319	9	metabolic	metabolic	NOUN
gs-3921	319	10	networks	network	NOUN
gs-3921	319	11	,	,	PUNCT
gs-3921	319	12	and	and	CCONJ
gs-3921	319	13	cellular	cellular	ADJ
gs-3921	319	14	signaling	signal	VERB
gs-3921	319	15	pathways	pathway	NOUN
gs-3921	319	16	to	to	PART
gs-3921	319	17	identify	identify	VERB
gs-3921	319	18	emergent	emergent	ADJ
gs-3921	319	19	vulnerabilities	vulnerability	NOUN
gs-3921	319	20	.	.	PUNCT
gs-3921	320	1	while	while	SCONJ
gs-3921	320	2	promising	promise	VERB
gs-3921	320	3	,	,	PUNCT
gs-3921	320	4	these	these	DET
gs-3921	320	5	approaches	approach	NOUN
gs-3921	320	6	require	require	VERB
gs-3921	320	7	large	large	ADJ
gs-3921	320	8	,	,	PUNCT
gs-3921	320	9	well	well	ADV
gs-3921	320	10	-	-	PUNCT
gs-3921	320	11	phenotyped	phenotype	VERB
gs-3921	320	12	cohorts	cohort	NOUN
gs-3921	320	13	and	and	CCONJ
gs-3921	320	14	advanced	advanced	ADJ
gs-3921	320	15	bioinformatics	bioinformatics	NOUN
gs-3921	320	16	capabilities	capability	NOUN
gs-3921	320	17	,	,	PUNCT
gs-3921	320	18	currently	currently	ADV
gs-3921	320	19	limiting	limit	VERB
gs-3921	320	20	widespread	widespread	ADJ
gs-3921	320	21	clinical	clinical	ADJ
gs-3921	320	22	application	application	NOUN
gs-3921	320	23	.	.	PUNCT
gs-3921	321	1	ethical	ethical	ADJ
gs-3921	321	2	,	,	PUNCT
gs-3921	321	3	legal	legal	ADJ
gs-3921	321	4	,	,	PUNCT
gs-3921	321	5	and	and	CCONJ
gs-3921	321	6	social	social	ADJ
gs-3921	321	7	considerations	consideration	NOUN
gs-3921	321	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	321	9	integration	integration	NOUN
gs-3921	321	10	raises	raise	VERB
gs-3921	321	11	profound	profound	ADJ
gs-3921	321	12	ethical	ethical	ADJ
gs-3921	321	13	,	,	PUNCT
gs-3921	321	14	legal	legal	ADJ
gs-3921	321	15	,	,	PUNCT
gs-3921	321	16	and	and	CCONJ
gs-3921	321	17	social	social	ADJ
gs-3921	321	18	implications	implication	NOUN
gs-3921	321	19	.	.	PUNCT
gs-3921	322	1	the	the	DET
gs-3921	322	2	sensitive	sensitive	ADJ
gs-3921	322	3	nature	nature	NOUN
gs-3921	322	4	of	of	ADP
gs-3921	322	5	genetic	genetic	ADJ
gs-3921	322	6	information	information	NOUN
gs-3921	322	7	mandates	mandate	VERB
gs-3921	322	8	rigorous	rigorous	ADJ
gs-3921	322	9	privacy	privacy	NOUN
gs-3921	322	10	protections	protection	NOUN
gs-3921	322	11	and	and	CCONJ
gs-3921	322	12	secure	secure	VERB
gs-3921	322	13	data	datum	NOUN
gs-3921	322	14	governance	governance	NOUN
gs-3921	322	15	frameworks	framework	NOUN
gs-3921	322	16	.	.	PUNCT
gs-3921	323	1	informed	inform	VERB
gs-3921	323	2	consent	consent	NOUN
gs-3921	323	3	processes	process	NOUN
gs-3921	323	4	must	must	AUX
gs-3921	323	5	be	be	AUX
gs-3921	323	6	transparent	transparent	ADJ
gs-3921	323	7	and	and	CCONJ
gs-3921	323	8	comprehensive	comprehensive	ADJ
gs-3921	323	9	,	,	PUNCT
gs-3921	323	10	ensuring	ensure	VERB
gs-3921	323	11	patient	patient	ADJ
gs-3921	323	12	understanding	understanding	NOUN
gs-3921	323	13	of	of	ADP
gs-3921	323	14	the	the	DET
gs-3921	323	15	scope	scope	NOUN
gs-3921	323	16	,	,	PUNCT
gs-3921	323	17	benefits	benefit	NOUN
gs-3921	323	18	,	,	PUNCT
gs-3921	323	19	limitations	limitation	NOUN
gs-3921	323	20	,	,	PUNCT
gs-3921	323	21	and	and	CCONJ
gs-3921	323	22	potential	potential	ADJ
gs-3921	323	23	risks	risk	NOUN
gs-3921	323	24	of	of	ADP
gs-3921	323	25	genetic	genetic	ADJ
gs-3921	323	26	testing	testing	NOUN
gs-3921	323	27	.	.	PUNCT
gs-3921	324	1	concerns	concern	NOUN
gs-3921	324	2	about	about	ADP
gs-3921	324	3	genetic	genetic	ADJ
gs-3921	324	4	discrimination	discrimination	NOUN
gs-3921	324	5	in	in	ADP
gs-3921	324	6	employment	employment	NOUN
gs-3921	324	7	,	,	PUNCT
gs-3921	324	8	insurance	insurance	NOUN
gs-3921	324	9	,	,	PUNCT
gs-3921	324	10	and	and	CCONJ
gs-3921	324	11	social	social	ADJ
gs-3921	324	12	contexts	context	NOUN
gs-3921	324	13	necessitate	necessitate	ADJ
gs-3921	324	14	protective	protective	ADJ
gs-3921	324	15	legislation	legislation	NOUN
gs-3921	324	16	such	such	ADJ
gs-3921	324	17	as	as	ADP
gs-3921	324	18	the	the	DET
gs-3921	324	19	genetic	genetic	ADJ
gs-3921	324	20	information	information	NOUN
gs-3921	324	21	nondiscrimination	nondiscrimination	PROPN
gs-3921	324	22	act	act	NOUN
gs-3921	324	23	in	in	ADP
gs-3921	324	24	the	the	DET
gs-3921	324	25	united	united	PROPN
gs-3921	324	26	states	states	PROPN
gs-3921	324	27	and	and	CCONJ
gs-3921	324	28	equivalent	equivalent	ADJ
gs-3921	324	29	policies	policy	NOUN
gs-3921	324	30	worldwide	worldwide	ADV
gs-3921	324	31	.	.	PUNCT
gs-3921	325	1	ensuring	ensure	VERB
gs-3921	325	2	equitable	equitable	ADJ
gs-3921	325	3	access	access	NOUN
gs-3921	325	4	to	to	ADP
gs-3921	325	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	325	6	services	service	NOUN
gs-3921	325	7	is	be	AUX
gs-3921	325	8	imperative	imperative	ADJ
gs-3921	325	9	to	to	PART
gs-3921	325	10	prevent	prevent	VERB
gs-3921	325	11	exacerbation	exacerbation	NOUN
gs-3921	325	12	of	of	ADP
gs-3921	325	13	health	health	NOUN
gs-3921	325	14	disparities	disparity	NOUN
gs-3921	325	15	,	,	PUNCT
gs-3921	325	16	necessitating	necessitate	VERB
gs-3921	325	17	inclusive	inclusive	ADJ
gs-3921	325	18	research	research	NOUN
gs-3921	325	19	and	and	CCONJ
gs-3921	325	20	culturally	culturally	ADV
gs-3921	325	21	competent	competent	ADJ
gs-3921	325	22	care	care	NOUN
gs-3921	325	23	models	model	NOUN
gs-3921	325	24	.	.	PUNCT
gs-3921	326	1	patient	patient	ADJ
gs-3921	326	2	autonomy	autonomy	NOUN
gs-3921	326	3	and	and	CCONJ
gs-3921	326	4	engagement	engagement	NOUN
gs-3921	326	5	are	be	AUX
gs-3921	326	6	central	central	ADJ
gs-3921	326	7	ethical	ethical	ADJ
gs-3921	326	8	principles	principle	NOUN
gs-3921	326	9	.	.	PUNCT
gs-3921	327	1	empowering	empower	VERB
gs-3921	327	2	patients	patient	NOUN
gs-3921	327	3	through	through	ADP
gs-3921	327	4	education	education	NOUN
gs-3921	327	5	and	and	CCONJ
gs-3921	327	6	participatory	participatory	ADJ
gs-3921	327	7	decision	decision	NOUN
gs-3921	327	8	-	-	PUNCT
gs-3921	327	9	making	making	NOUN
gs-3921	327	10	enhances	enhance	NOUN
gs-3921	327	11	trust	trust	VERB
gs-3921	327	12	and	and	CCONJ
gs-3921	327	13	optimizes	optimize	VERB
gs-3921	327	14	therapeutic	therapeutic	ADJ
gs-3921	327	15	outcomes	outcome	NOUN
gs-3921	327	16	.	.	PUNCT
gs-3921	328	1	the	the	DET
gs-3921	328	2	responsible	responsible	ADJ
gs-3921	328	3	handling	handling	NOUN
gs-3921	328	4	of	of	ADP
gs-3921	328	5	incidental	incidental	ADJ
gs-3921	328	6	findings	finding	NOUN
gs-3921	328	7	,	,	PUNCT
gs-3921	328	8	which	which	PRON
gs-3921	328	9	may	may	AUX
gs-3921	328	10	arise	arise	VERB
gs-3921	328	11	from	from	ADP
gs-3921	328	12	broad	broad	ADJ
gs-3921	328	13	genomic	genomic	ADJ
gs-3921	328	14	testing	testing	NOUN
gs-3921	328	15	,	,	PUNCT
gs-3921	328	16	requires	require	VERB
gs-3921	328	17	clear	clear	ADJ
gs-3921	328	18	guidelines	guideline	NOUN
gs-3921	328	19	and	and	CCONJ
gs-3921	328	20	expert	expert	NOUN
gs-3921	328	21	consultation	consultation	NOUN
gs-3921	328	22	.	.	PUNCT
gs-3921	329	1	health	health	NOUN
gs-3921	329	2	economic	economic	ADJ
gs-3921	329	3	perspectives	perspective	NOUN
gs-3921	329	4	health	health	NOUN
gs-3921	329	5	economic	economic	ADJ
gs-3921	329	6	analyses	analysis	NOUN
gs-3921	329	7	play	play	VERB
gs-3921	329	8	a	a	DET
gs-3921	329	9	decisive	decisive	ADJ
gs-3921	329	10	role	role	NOUN
gs-3921	329	11	in	in	ADP
gs-3921	329	12	informing	inform	VERB
gs-3921	329	13	policy	policy	NOUN
gs-3921	329	14	and	and	CCONJ
gs-3921	329	15	reimbursement	reimbursement	NOUN
gs-3921	329	16	decisions	decision	NOUN
gs-3921	329	17	for	for	ADP
gs-3921	329	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	329	19	testing	testing	NOUN
gs-3921	329	20	.	.	PUNCT
gs-3921	330	1	studies	study	NOUN
gs-3921	330	2	demonstrate	demonstrate	VERB
gs-3921	330	3	costeffectiveness	costeffectiveness	NOUN
gs-3921	330	4	in	in	ADP
gs-3921	330	5	several	several	ADJ
gs-3921	330	6	clinical	clinical	ADJ
gs-3921	330	7	contexts	context	NOUN
gs-3921	330	8	by	by	ADP
gs-3921	330	9	reducing	reduce	VERB
gs-3921	330	10	adr	adr	PROPN
gs-3921	330	11	-	-	PUNCT
gs-3921	330	12	related	relate	VERB
gs-3921	330	13	hospitalizations	hospitalization	NOUN
gs-3921	330	14	and	and	CCONJ
gs-3921	330	15	improving	improve	VERB
gs-3921	330	16	therapeutic	therapeutic	ADJ
gs-3921	330	17	efficacy	efficacy	NOUN
gs-3921	330	18	.	.	PUNCT
gs-3921	331	1	however	however	ADV
gs-3921	331	2	,	,	PUNCT
gs-3921	331	3	variability	variability	NOUN
gs-3921	331	4	in	in	ADP
gs-3921	331	5	study	study	NOUN
gs-3921	331	6	designs	design	NOUN
gs-3921	331	7	,	,	PUNCT
gs-3921	331	8	populations	population	NOUN
gs-3921	331	9	,	,	PUNCT
gs-3921	331	10	cost	cost	NOUN
gs-3921	331	11	inputs	input	NOUN
gs-3921	331	12	,	,	PUNCT
gs-3921	331	13	and	and	CCONJ
gs-3921	331	14	outcome	outcome	NOUN
gs-3921	331	15	measures	measure	NOUN
gs-3921	331	16	limits	limit	VERB
gs-3921	331	17	generalizability	generalizability	NOUN
gs-3921	331	18	.	.	PUNCT
gs-3921	332	1	georgian	georgian	ADJ
gs-3921	332	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	332	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	332	4	ტ.	ტ.	VERB
gs-3921	332	5	7	7	NUM
gs-3921	332	6	n	n	PRON
gs-3921	332	7	3	3	NUM
gs-3921	332	8	,	,	PUNCT
gs-3921	332	9	2025	2025	NUM
gs-3921	332	10	237	237	NUM
gs-3921	332	11	future	future	ADJ
gs-3921	332	12	economic	economic	ADJ
gs-3921	332	13	evaluations	evaluation	NOUN
gs-3921	332	14	must	must	AUX
gs-3921	332	15	incorporate	incorporate	VERB
gs-3921	332	16	broader	broad	ADJ
gs-3921	332	17	societal	societal	ADJ
gs-3921	332	18	impacts	impact	NOUN
gs-3921	332	19	,	,	PUNCT
gs-3921	332	20	including	include	VERB
gs-3921	332	21	quality	quality	NOUN
gs-3921	332	22	-	-	PUNCT
gs-3921	332	23	adjusted	adjust	VERB
gs-3921	332	24	life	life	NOUN
gs-3921	332	25	years	year	NOUN
gs-3921	332	26	,	,	PUNCT
gs-3921	332	27	productivity	productivity	NOUN
gs-3921	332	28	,	,	PUNCT
gs-3921	332	29	caregiver	caregiver	NOUN
gs-3921	332	30	burden	burden	NOUN
gs-3921	332	31	,	,	PUNCT
gs-3921	332	32	and	and	CCONJ
gs-3921	332	33	long	long	ADJ
gs-3921	332	34	-	-	PUNCT
gs-3921	332	35	term	term	NOUN
gs-3921	332	36	healthcare	healthcare	NOUN
gs-3921	332	37	costs	cost	NOUN
gs-3921	332	38	.	.	PUNCT
gs-3921	333	1	innovative	innovative	ADJ
gs-3921	333	2	reimbursement	reimbursement	NOUN
gs-3921	333	3	models	model	NOUN
gs-3921	333	4	,	,	PUNCT
gs-3921	333	5	such	such	ADJ
gs-3921	333	6	as	as	ADP
gs-3921	333	7	value	value	NOUN
gs-3921	333	8	-	-	PUNCT
gs-3921	333	9	based	base	VERB
gs-3921	333	10	care	care	NOUN
gs-3921	333	11	and	and	CCONJ
gs-3921	333	12	risk	risk	NOUN
gs-3921	333	13	-	-	PUNCT
gs-3921	333	14	sharing	share	VERB
gs-3921	333	15	agreements	agreement	NOUN
gs-3921	333	16	,	,	PUNCT
gs-3921	333	17	may	may	AUX
gs-3921	333	18	accelerate	accelerate	VERB
gs-3921	333	19	adoption	adoption	NOUN
gs-3921	333	20	by	by	ADP
gs-3921	333	21	aligning	align	VERB
gs-3921	333	22	incentives	incentive	NOUN
gs-3921	333	23	with	with	ADP
gs-3921	333	24	improved	improved	ADJ
gs-3921	333	25	patient	patient	ADJ
gs-3921	333	26	outcomes	outcome	NOUN
gs-3921	333	27	and	and	CCONJ
gs-3921	333	28	cost	cost	VERB
gs-3921	333	29	savings	saving	NOUN
gs-3921	333	30	.	.	PUNCT
gs-3921	334	1	technological	technological	ADJ
gs-3921	334	2	innovations	innovation	NOUN
gs-3921	334	3	and	and	CCONJ
gs-3921	334	4	digital	digital	ADJ
gs-3921	334	5	health	health	NOUN
gs-3921	334	6	integration	integration	NOUN
gs-3921	334	7	the	the	DET
gs-3921	334	8	digital	digital	ADJ
gs-3921	334	9	transformation	transformation	NOUN
gs-3921	334	10	of	of	ADP
gs-3921	334	11	healthcare	healthcare	NOUN
gs-3921	334	12	catalyzes	catalyze	VERB
gs-3921	334	13	novel	novel	ADJ
gs-3921	334	14	opportunities	opportunity	NOUN
gs-3921	334	15	for	for	ADP
gs-3921	334	16	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	334	17	and	and	CCONJ
gs-3921	334	18	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	334	19	.	.	PUNCT
gs-3921	335	1	artificial	artificial	ADJ
gs-3921	335	2	intelligence	intelligence	NOUN
gs-3921	335	3	and	and	CCONJ
gs-3921	335	4	machine	machine	NOUN
gs-3921	335	5	learning	learn	VERB
gs-3921	335	6	algorithms	algorithm	NOUN
gs-3921	335	7	enhance	enhance	VERB
gs-3921	335	8	the	the	DET
gs-3921	335	9	analysis	analysis	NOUN
gs-3921	335	10	of	of	ADP
gs-3921	335	11	complex	complex	ADJ
gs-3921	335	12	datasets	dataset	NOUN
gs-3921	335	13	to	to	PART
gs-3921	335	14	identify	identify	VERB
gs-3921	335	15	subtle	subtle	ADJ
gs-3921	335	16	gene	gene	NOUN
gs-3921	335	17	-	-	PUNCT
gs-3921	335	18	drug	drug	NOUN
gs-3921	335	19	interactions	interaction	NOUN
gs-3921	335	20	and	and	CCONJ
gs-3921	335	21	predict	predict	VERB
gs-3921	335	22	adverse	adverse	ADJ
gs-3921	335	23	event	event	NOUN
gs-3921	335	24	risk	risk	NOUN
gs-3921	335	25	with	with	ADP
gs-3921	335	26	high	high	ADJ
gs-3921	335	27	accuracy	accuracy	NOUN
gs-3921	335	28	.	.	PUNCT
gs-3921	336	1	natural	natural	ADJ
gs-3921	336	2	language	language	NOUN
gs-3921	336	3	processing	processing	NOUN
gs-3921	336	4	facilitates	facilitate	VERB
gs-3921	336	5	extraction	extraction	NOUN
gs-3921	336	6	of	of	ADP
gs-3921	336	7	adverse	adverse	ADJ
gs-3921	336	8	event	event	NOUN
gs-3921	336	9	information	information	NOUN
gs-3921	336	10	from	from	ADP
gs-3921	336	11	unstructured	unstructured	ADJ
gs-3921	336	12	clinical	clinical	ADJ
gs-3921	336	13	notes	note	NOUN
gs-3921	336	14	.	.	PUNCT
gs-3921	337	1	mobile	mobile	ADJ
gs-3921	337	2	health	health	NOUN
gs-3921	337	3	applications	application	NOUN
gs-3921	337	4	and	and	CCONJ
gs-3921	337	5	wearable	wearable	ADJ
gs-3921	337	6	biosensors	biosensor	NOUN
gs-3921	337	7	enable	enable	VERB
gs-3921	337	8	continuous	continuous	ADJ
gs-3921	337	9	,	,	PUNCT
gs-3921	337	10	real	real	ADJ
gs-3921	337	11	-	-	PUNCT
gs-3921	337	12	time	time	NOUN
gs-3921	337	13	patient	patient	ADJ
gs-3921	337	14	monitoring	monitoring	NOUN
gs-3921	337	15	,	,	PUNCT
gs-3921	337	16	capturing	capture	VERB
gs-3921	337	17	physiological	physiological	ADJ
gs-3921	337	18	and	and	CCONJ
gs-3921	337	19	behavioral	behavioral	ADJ
gs-3921	337	20	data	datum	NOUN
gs-3921	337	21	indicative	indicative	ADJ
gs-3921	337	22	of	of	ADP
gs-3921	337	23	adverse	adverse	ADJ
gs-3921	337	24	drug	drug	NOUN
gs-3921	337	25	reactions	reaction	NOUN
gs-3921	337	26	.	.	PUNCT
gs-3921	338	1	integration	integration	NOUN
gs-3921	338	2	of	of	ADP
gs-3921	338	3	these	these	DET
gs-3921	338	4	digital	digital	ADJ
gs-3921	338	5	health	health	NOUN
gs-3921	338	6	tools	tool	NOUN
gs-3921	338	7	with	with	ADP
gs-3921	338	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	338	9	profiles	profile	NOUN
gs-3921	338	10	fosters	foster	VERB
gs-3921	338	11	proactive	proactive	ADJ
gs-3921	338	12	,	,	PUNCT
gs-3921	338	13	personalized	personalized	ADJ
gs-3921	338	14	interventions	intervention	NOUN
gs-3921	338	15	.	.	PUNCT
gs-3921	339	1	blockchain	blockchain	PROPN
gs-3921	339	2	technology	technology	PROPN
gs-3921	339	3	offers	offer	VERB
gs-3921	339	4	promising	promise	VERB
gs-3921	339	5	solutions	solution	NOUN
gs-3921	339	6	for	for	ADP
gs-3921	339	7	secure	secure	ADJ
gs-3921	339	8	,	,	PUNCT
gs-3921	339	9	decentralized	decentralized	ADJ
gs-3921	339	10	management	management	NOUN
gs-3921	339	11	of	of	ADP
gs-3921	339	12	sensitive	sensitive	ADJ
gs-3921	339	13	genetic	genetic	ADJ
gs-3921	339	14	and	and	CCONJ
gs-3921	339	15	health	health	NOUN
gs-3921	339	16	data	datum	NOUN
gs-3921	339	17	,	,	PUNCT
gs-3921	339	18	enhancing	enhance	VERB
gs-3921	339	19	patient	patient	ADJ
gs-3921	339	20	control	control	NOUN
gs-3921	339	21	and	and	CCONJ
gs-3921	339	22	data	datum	NOUN
gs-3921	339	23	interoperability	interoperability	NOUN
gs-3921	339	24	.	.	PUNCT
gs-3921	340	1	however	however	ADV
gs-3921	340	2	,	,	PUNCT
gs-3921	340	3	technological	technological	ADJ
gs-3921	340	4	adoption	adoption	NOUN
gs-3921	340	5	must	must	AUX
gs-3921	340	6	be	be	AUX
gs-3921	340	7	accompanied	accompany	VERB
gs-3921	340	8	by	by	ADP
gs-3921	340	9	rigorous	rigorous	ADJ
gs-3921	340	10	validation	validation	NOUN
gs-3921	340	11	,	,	PUNCT
gs-3921	340	12	user	user	NOUN
gs-3921	340	13	-	-	PUNCT
gs-3921	340	14	centered	center	VERB
gs-3921	340	15	design	design	NOUN
gs-3921	340	16	,	,	PUNCT
gs-3921	340	17	and	and	CCONJ
gs-3921	340	18	ethical	ethical	ADJ
gs-3921	340	19	governance	governance	NOUN
gs-3921	340	20	frameworks	framework	NOUN
gs-3921	340	21	to	to	PART
gs-3921	340	22	ensure	ensure	VERB
gs-3921	340	23	safety	safety	NOUN
gs-3921	340	24	,	,	PUNCT
gs-3921	340	25	efficacy	efficacy	NOUN
gs-3921	340	26	,	,	PUNCT
gs-3921	340	27	and	and	CCONJ
gs-3921	340	28	equity	equity	NOUN
gs-3921	340	29	.	.	PUNCT
gs-3921	341	1	global	global	ADJ
gs-3921	341	2	health	health	NOUN
gs-3921	341	3	and	and	CCONJ
gs-3921	341	4	policy	policy	NOUN
gs-3921	341	5	perspectives	perspective	NOUN
gs-3921	341	6	the	the	DET
gs-3921	341	7	global	global	ADJ
gs-3921	341	8	health	health	NOUN
gs-3921	341	9	community	community	NOUN
gs-3921	341	10	increasingly	increasingly	ADV
gs-3921	341	11	recognizes	recognize	VERB
gs-3921	341	12	the	the	DET
gs-3921	341	13	potential	potential	NOUN
gs-3921	341	14	of	of	ADP
gs-3921	341	15	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	341	16	and	and	CCONJ
gs-3921	341	17	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	341	18	to	to	PART
gs-3921	341	19	improve	improve	VERB
gs-3921	341	20	medication	medication	NOUN
gs-3921	341	21	safety	safety	NOUN
gs-3921	341	22	and	and	CCONJ
gs-3921	341	23	efficacy	efficacy	NOUN
gs-3921	341	24	worldwide	worldwide	ADV
gs-3921	341	25	.	.	PUNCT
gs-3921	342	1	collaborative	collaborative	ADJ
gs-3921	342	2	initiatives	initiative	NOUN
gs-3921	342	3	aim	aim	VERB
gs-3921	342	4	to	to	PART
gs-3921	342	5	build	build	VERB
gs-3921	342	6	capacity	capacity	NOUN
gs-3921	342	7	in	in	ADP
gs-3921	342	8	lowand	lowand	ADJ
gs-3921	342	9	middle	middle	ADJ
gs-3921	342	10	-	-	PUNCT
gs-3921	342	11	income	income	NOUN
gs-3921	342	12	countries	country	NOUN
gs-3921	342	13	through	through	ADP
gs-3921	342	14	technology	technology	NOUN
gs-3921	342	15	transfer	transfer	NOUN
gs-3921	342	16	,	,	PUNCT
gs-3921	342	17	training	training	NOUN
gs-3921	342	18	,	,	PUNCT
gs-3921	342	19	and	and	CCONJ
gs-3921	342	20	infrastructure	infrastructure	NOUN
gs-3921	342	21	development	development	NOUN
gs-3921	342	22	.	.	PUNCT
gs-3921	343	1	the	the	DET
gs-3921	343	2	underrepresentation	underrepresentation	NOUN
gs-3921	343	3	of	of	ADP
gs-3921	343	4	diverse	diverse	ADJ
gs-3921	343	5	populations	population	NOUN
gs-3921	343	6	in	in	ADP
gs-3921	343	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	343	8	research	research	NOUN
gs-3921	343	9	limits	limit	VERB
gs-3921	343	10	applicability	applicability	NOUN
gs-3921	343	11	of	of	ADP
gs-3921	343	12	findings	finding	NOUN
gs-3921	343	13	,	,	PUNCT
gs-3921	343	14	underscoring	underscore	VERB
gs-3921	343	15	the	the	DET
gs-3921	343	16	need	need	NOUN
gs-3921	343	17	for	for	ADP
gs-3921	343	18	inclusive	inclusive	ADJ
gs-3921	343	19	,	,	PUNCT
gs-3921	343	20	global	global	ADJ
gs-3921	343	21	genomic	genomic	NOUN
gs-3921	343	22	databases	database	NOUN
gs-3921	343	23	and	and	CCONJ
gs-3921	343	24	research	research	NOUN
gs-3921	343	25	consortia	consortia	NOUN
gs-3921	343	26	.	.	PUNCT
gs-3921	344	1	harmonization	harmonization	NOUN
gs-3921	344	2	of	of	ADP
gs-3921	344	3	regulatory	regulatory	ADJ
gs-3921	344	4	standards	standard	NOUN
gs-3921	344	5	and	and	CCONJ
gs-3921	344	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	344	7	guidelines	guideline	NOUN
gs-3921	344	8	facilitates	facilitate	VERB
gs-3921	344	9	international	international	ADJ
gs-3921	344	10	data	datum	NOUN
gs-3921	344	11	sharing	sharing	NOUN
gs-3921	344	12	and	and	CCONJ
gs-3921	344	13	clinical	clinical	ADJ
gs-3921	344	14	adoption	adoption	NOUN
gs-3921	344	15	.	.	PUNCT
gs-3921	345	1	health	health	NOUN
gs-3921	345	2	policies	policy	NOUN
gs-3921	345	3	must	must	AUX
gs-3921	345	4	evolve	evolve	VERB
gs-3921	345	5	to	to	PART
gs-3921	345	6	support	support	VERB
gs-3921	345	7	sustainable	sustainable	ADJ
gs-3921	345	8	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	345	9	services	service	NOUN
gs-3921	345	10	,	,	PUNCT
gs-3921	345	11	including	include	VERB
gs-3921	345	12	standardized	standardized	ADJ
gs-3921	345	13	testing	testing	NOUN
gs-3921	345	14	protocols	protocol	NOUN
gs-3921	345	15	,	,	PUNCT
gs-3921	345	16	reimbursement	reimbursement	NOUN
gs-3921	345	17	mechanisms	mechanism	NOUN
gs-3921	345	18	,	,	PUNCT
gs-3921	345	19	and	and	CCONJ
gs-3921	345	20	educational	educational	ADJ
gs-3921	345	21	frameworks	framework	NOUN
gs-3921	345	22	.	.	PUNCT
gs-3921	346	1	stakeholder	stakeholder	NOUN
gs-3921	346	2	engagement	engagement	NOUN
gs-3921	346	3	—	—	PUNCT
gs-3921	346	4	patients	patient	NOUN
gs-3921	346	5	,	,	PUNCT
gs-3921	346	6	clinicians	clinician	NOUN
gs-3921	346	7	,	,	PUNCT
gs-3921	346	8	researchers	researcher	NOUN
gs-3921	346	9	,	,	PUNCT
gs-3921	346	10	industry	industry	NOUN
gs-3921	346	11	,	,	PUNCT
gs-3921	346	12	and	and	CCONJ
gs-3921	346	13	regulators	regulator	NOUN
gs-3921	346	14	—	—	PUNCT
gs-3921	346	15	is	be	AUX
gs-3921	346	16	essential	essential	ADJ
gs-3921	346	17	to	to	PART
gs-3921	346	18	foster	foster	VERB
gs-3921	346	19	trust	trust	NOUN
gs-3921	346	20	,	,	PUNCT
gs-3921	346	21	transparency	transparency	NOUN
gs-3921	346	22	,	,	PUNCT
gs-3921	346	23	and	and	CCONJ
gs-3921	346	24	ethical	ethical	ADJ
gs-3921	346	25	implementation	implementation	NOUN
gs-3921	346	26	.	.	PUNCT
gs-3921	347	1	the	the	DET
gs-3921	347	2	intersection	intersection	NOUN
gs-3921	347	3	of	of	ADP
gs-3921	347	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	347	5	,	,	PUNCT
gs-3921	347	6	patient	patient	NOUN
gs-3921	347	7	-	-	PUNCT
gs-3921	347	8	centered	center	VERB
gs-3921	347	9	care	care	NOUN
gs-3921	347	10	,	,	PUNCT
gs-3921	347	11	and	and	CCONJ
gs-3921	347	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	347	13	heralds	herald	VERB
gs-3921	347	14	a	a	DET
gs-3921	347	15	transformative	transformative	ADJ
gs-3921	347	16	era	era	NOUN
gs-3921	347	17	in	in	ADP
gs-3921	347	18	the	the	DET
gs-3921	347	19	optimization	optimization	NOUN
gs-3921	347	20	of	of	ADP
gs-3921	347	21	medication	medication	NOUN
gs-3921	347	22	safety	safety	NOUN
gs-3921	347	23	and	and	CCONJ
gs-3921	347	24	efficacy	efficacy	NOUN
gs-3921	347	25	.	.	PUNCT
gs-3921	348	1	the	the	DET
gs-3921	348	2	growing	grow	VERB
gs-3921	348	3	recognition	recognition	NOUN
gs-3921	348	4	that	that	SCONJ
gs-3921	348	5	genetic	genetic	ADJ
gs-3921	348	6	variability	variability	NOUN
gs-3921	348	7	significantly	significantly	ADV
gs-3921	348	8	contributes	contribute	VERB
gs-3921	348	9	to	to	PART
gs-3921	348	10	interindividual	interindividual	VERB
gs-3921	348	11	differences	difference	NOUN
gs-3921	348	12	in	in	ADP
gs-3921	348	13	drug	drug	NOUN
gs-3921	348	14	response	response	NOUN
gs-3921	348	15	has	have	AUX
gs-3921	348	16	propelled	propel	VERB
gs-3921	348	17	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	348	18	from	from	ADP
gs-3921	348	19	a	a	DET
gs-3921	348	20	predominantly	predominantly	ADV
gs-3921	348	21	research	research	NOUN
gs-3921	348	22	-	-	PUNCT
gs-3921	348	23	focused	focus	VERB
gs-3921	348	24	domain	domain	NOUN
gs-3921	348	25	to	to	ADP
gs-3921	348	26	a	a	DET
gs-3921	348	27	clinically	clinically	ADV
gs-3921	348	28	actionable	actionable	ADJ
gs-3921	348	29	tool	tool	NOUN
gs-3921	348	30	.	.	PUNCT
gs-3921	349	1	this	this	DET
gs-3921	349	2	analysis	analysis	NOUN
gs-3921	349	3	georgian	georgian	ADJ
gs-3921	349	4	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	349	5	მეცნიერები	მეცნიერები	NOUN
gs-3921	349	6	ტ.	ტ.	VERB
gs-3921	349	7	7	7	NUM
gs-3921	349	8	n	n	PRON
gs-3921	349	9	3	3	NUM
gs-3921	349	10	,	,	PUNCT
gs-3921	349	11	2025	2025	NUM
gs-3921	349	12	238	238	NUM
gs-3921	349	13	elucidates	elucidate	VERB
gs-3921	349	14	the	the	DET
gs-3921	349	15	multifaceted	multifaceted	ADJ
gs-3921	349	16	outcomes	outcome	NOUN
gs-3921	349	17	,	,	PUNCT
gs-3921	349	18	challenges	challenge	NOUN
gs-3921	349	19	,	,	PUNCT
gs-3921	349	20	and	and	CCONJ
gs-3921	349	21	future	future	ADJ
gs-3921	349	22	directions	direction	NOUN
gs-3921	349	23	stemming	stem	VERB
gs-3921	349	24	from	from	ADP
gs-3921	349	25	the	the	DET
gs-3921	349	26	integration	integration	NOUN
gs-3921	349	27	of	of	ADP
gs-3921	349	28	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	349	29	data	datum	NOUN
gs-3921	349	30	with	with	ADP
gs-3921	349	31	patient	patient	NOUN
gs-3921	349	32	-	-	PUNCT
gs-3921	349	33	centered	center	VERB
gs-3921	349	34	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	349	35	strategies	strategy	NOUN
gs-3921	349	36	and	and	CCONJ
gs-3921	349	37	advanced	advanced	ADJ
gs-3921	349	38	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	349	39	systems	system	NOUN
gs-3921	349	40	.	.	PUNCT
gs-3921	350	1	genetic	genetic	ADJ
gs-3921	350	2	influences	influence	NOUN
gs-3921	350	3	on	on	ADP
gs-3921	350	4	medication	medication	NOUN
gs-3921	350	5	-	-	PUNCT
gs-3921	350	6	induced	induce	VERB
gs-3921	350	7	adverse	adverse	ADJ
gs-3921	350	8	effects	effect	NOUN
gs-3921	350	9	:	:	PUNCT
gs-3921	350	10	expanding	expand	VERB
gs-3921	350	11	the	the	DET
gs-3921	350	12	evidence	evidence	NOUN
gs-3921	350	13	base	base	NOUN
gs-3921	350	14	a	a	DET
gs-3921	350	15	robust	robust	ADJ
gs-3921	350	16	body	body	NOUN
gs-3921	350	17	of	of	ADP
gs-3921	350	18	evidence	evidence	NOUN
gs-3921	350	19	underscores	underscore	VERB
gs-3921	350	20	that	that	SCONJ
gs-3921	350	21	genetic	genetic	ADJ
gs-3921	350	22	polymorphisms	polymorphism	NOUN
gs-3921	350	23	in	in	ADP
gs-3921	350	24	drugmetabolizing	drugmetabolize	VERB
gs-3921	350	25	enzymes	enzyme	NOUN
gs-3921	350	26	,	,	PUNCT
gs-3921	350	27	transporters	transporter	NOUN
gs-3921	350	28	,	,	PUNCT
gs-3921	350	29	and	and	CCONJ
gs-3921	350	30	targets	target	NOUN
gs-3921	350	31	critically	critically	ADV
gs-3921	350	32	influence	influence	VERB
gs-3921	350	33	the	the	DET
gs-3921	350	34	occurrence	occurrence	NOUN
gs-3921	350	35	and	and	CCONJ
gs-3921	350	36	severity	severity	NOUN
gs-3921	350	37	of	of	ADP
gs-3921	350	38	adverse	adverse	ADJ
gs-3921	350	39	drug	drug	NOUN
gs-3921	350	40	reactions	reaction	NOUN
gs-3921	350	41	(	(	PUNCT
gs-3921	350	42	adrs	adrs	PROPN
gs-3921	350	43	)	)	PUNCT
gs-3921	350	44	.	.	PUNCT
gs-3921	351	1	the	the	DET
gs-3921	351	2	cytochrome	cytochrome	NOUN
gs-3921	351	3	p450	p450	NUM
gs-3921	351	4	superfamily	superfamily	NOUN
gs-3921	351	5	remains	remain	VERB
gs-3921	351	6	a	a	DET
gs-3921	351	7	cornerstone	cornerstone	NOUN
gs-3921	351	8	of	of	ADP
gs-3921	351	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	351	10	research	research	NOUN
gs-3921	351	11	,	,	PUNCT
gs-3921	351	12	with	with	ADP
gs-3921	351	13	enzymes	enzyme	NOUN
gs-3921	351	14	such	such	ADJ
gs-3921	351	15	as	as	ADP
gs-3921	351	16	cyp2d6	cyp2d6	NOUN
gs-3921	351	17	,	,	PUNCT
gs-3921	351	18	cyp2c19	cyp2c19	PROPN
gs-3921	351	19	,	,	PUNCT
gs-3921	351	20	cyp2c9	cyp2c9	NOUN
gs-3921	351	21	,	,	PUNCT
gs-3921	351	22	and	and	CCONJ
gs-3921	351	23	cyp3a5	cyp3a5	NOUN
gs-3921	351	24	exhibiting	exhibit	VERB
gs-3921	351	25	extensive	extensive	ADJ
gs-3921	351	26	allelic	allelic	ADJ
gs-3921	351	27	variation	variation	NOUN
gs-3921	351	28	that	that	PRON
gs-3921	351	29	modulates	modulate	VERB
gs-3921	351	30	metabolic	metabolic	NOUN
gs-3921	351	31	capacity	capacity	NOUN
gs-3921	351	32	.	.	PUNCT
gs-3921	352	1	clinical	clinical	ADJ
gs-3921	352	2	guidelines	guideline	NOUN
gs-3921	352	3	issued	issue	VERB
gs-3921	352	4	by	by	ADP
gs-3921	352	5	international	international	ADJ
gs-3921	352	6	consortia	consortium	NOUN
gs-3921	352	7	like	like	ADP
gs-3921	352	8	the	the	DET
gs-3921	352	9	clinical	clinical	ADJ
gs-3921	352	10	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	352	11	implementation	implementation	NOUN
gs-3921	352	12	consortium	consortium	PROPN
gs-3921	352	13	(	(	PUNCT
gs-3921	352	14	cpic	cpic	NOUN
gs-3921	352	15	)	)	PUNCT
gs-3921	352	16	have	have	AUX
gs-3921	352	17	formalized	formalize	VERB
gs-3921	352	18	genotype	genotype	NOUN
gs-3921	352	19	-	-	PUNCT
gs-3921	352	20	guided	guide	VERB
gs-3921	352	21	dosing	dose	VERB
gs-3921	352	22	recommendations	recommendation	NOUN
gs-3921	352	23	for	for	ADP
gs-3921	352	24	numerous	numerous	ADJ
gs-3921	352	25	drugs	drug	NOUN
gs-3921	352	26	,	,	PUNCT
gs-3921	352	27	reinforcing	reinforce	VERB
gs-3921	352	28	the	the	DET
gs-3921	352	29	clinical	clinical	ADJ
gs-3921	352	30	utility	utility	NOUN
gs-3921	352	31	of	of	ADP
gs-3921	352	32	genotyping	genotype	VERB
gs-3921	352	33	in	in	ADP
gs-3921	352	34	minimizing	minimize	VERB
gs-3921	352	35	toxicity	toxicity	NOUN
gs-3921	352	36	and	and	CCONJ
gs-3921	352	37	enhancing	enhance	VERB
gs-3921	352	38	therapeutic	therapeutic	ADJ
gs-3921	352	39	efficacy	efficacy	NOUN
gs-3921	352	40	.	.	PUNCT
gs-3921	353	1	recent	recent	ADJ
gs-3921	353	2	meta	meta	ADJ
gs-3921	353	3	-	-	PUNCT
gs-3921	353	4	analyses	analysis	NOUN
gs-3921	353	5	have	have	AUX
gs-3921	353	6	quantified	quantify	VERB
gs-3921	353	7	the	the	DET
gs-3921	353	8	magnitude	magnitude	NOUN
gs-3921	353	9	of	of	ADP
gs-3921	353	10	risk	risk	NOUN
gs-3921	353	11	associated	associate	VERB
gs-3921	353	12	with	with	ADP
gs-3921	353	13	specific	specific	ADJ
gs-3921	353	14	genotypes	genotype	NOUN
gs-3921	353	15	.	.	PUNCT
gs-3921	354	1	for	for	ADP
gs-3921	354	2	instance	instance	NOUN
gs-3921	354	3	,	,	PUNCT
gs-3921	354	4	cyp2c19	cyp2c19	ADJ
gs-3921	354	5	poor	poor	ADJ
gs-3921	354	6	metabolizers	metabolizer	NOUN
gs-3921	354	7	have	have	AUX
gs-3921	354	8	demonstrated	demonstrate	VERB
gs-3921	354	9	a	a	DET
gs-3921	354	10	significantly	significantly	ADV
gs-3921	354	11	elevated	elevated	ADJ
gs-3921	354	12	risk	risk	NOUN
gs-3921	354	13	of	of	ADP
gs-3921	354	14	treatment	treatment	NOUN
gs-3921	354	15	failure	failure	NOUN
gs-3921	354	16	and	and	CCONJ
gs-3921	354	17	bleeding	bleed	VERB
gs-3921	354	18	complications	complication	NOUN
gs-3921	354	19	with	with	ADP
gs-3921	354	20	clopidogrel	clopidogrel	NOUN
gs-3921	354	21	therapy	therapy	NOUN
gs-3921	354	22	,	,	PUNCT
gs-3921	354	23	warranting	warrant	VERB
gs-3921	354	24	alternative	alternative	ADJ
gs-3921	354	25	antiplatelet	antiplatelet	NOUN
gs-3921	354	26	strategies	strategy	NOUN
gs-3921	354	27	.	.	PUNCT
gs-3921	355	1	similarly	similarly	ADV
gs-3921	355	2	,	,	PUNCT
gs-3921	355	3	carriers	carrier	NOUN
gs-3921	355	4	of	of	ADP
gs-3921	355	5	cyp2d6	cyp2d6	NOUN
gs-3921	355	6	ultrarapid	ultrarapid	NOUN
gs-3921	355	7	metabolizer	metabolizer	NOUN
gs-3921	355	8	alleles	allele	NOUN
gs-3921	355	9	face	face	VERB
gs-3921	355	10	increased	increase	VERB
gs-3921	355	11	likelihood	likelihood	NOUN
gs-3921	355	12	of	of	ADP
gs-3921	355	13	opioid	opioid	ADJ
gs-3921	355	14	toxicity	toxicity	NOUN
gs-3921	355	15	due	due	ADP
gs-3921	355	16	to	to	ADP
gs-3921	355	17	accelerated	accelerate	VERB
gs-3921	355	18	bioactivation	bioactivation	NOUN
gs-3921	355	19	of	of	ADP
gs-3921	355	20	prodrugs	prodrug	NOUN
gs-3921	355	21	such	such	ADJ
gs-3921	355	22	as	as	ADP
gs-3921	355	23	codeine	codeine	NOUN
gs-3921	355	24	.	.	PUNCT
gs-3921	356	1	these	these	DET
gs-3921	356	2	findings	finding	NOUN
gs-3921	356	3	substantiate	substantiate	VERB
gs-3921	356	4	genotype	genotype	NOUN
gs-3921	356	5	-	-	PUNCT
gs-3921	356	6	based	base	VERB
gs-3921	356	7	prescribing	prescribing	NOUN
gs-3921	356	8	as	as	ADP
gs-3921	356	9	a	a	DET
gs-3921	356	10	critical	critical	ADJ
gs-3921	356	11	component	component	NOUN
gs-3921	356	12	of	of	ADP
gs-3921	356	13	personalized	personalized	ADJ
gs-3921	356	14	medicine	medicine	NOUN
gs-3921	356	15	,	,	PUNCT
gs-3921	356	16	particularly	particularly	ADV
gs-3921	356	17	in	in	ADP
gs-3921	356	18	cardiovascular	cardiovascular	ADJ
gs-3921	356	19	,	,	PUNCT
gs-3921	356	20	psychiatric	psychiatric	ADJ
gs-3921	356	21	,	,	PUNCT
gs-3921	356	22	and	and	CCONJ
gs-3921	356	23	pain	pain	NOUN
gs-3921	356	24	management	management	NOUN
gs-3921	356	25	domains	domain	NOUN
gs-3921	356	26	.	.	PUNCT
gs-3921	357	1	the	the	DET
gs-3921	357	2	role	role	NOUN
gs-3921	357	3	of	of	ADP
gs-3921	357	4	hla	hla	PROPN
gs-3921	357	5	alleles	allele	NOUN
gs-3921	357	6	in	in	ADP
gs-3921	357	7	mediating	mediate	VERB
gs-3921	357	8	immune	immune	NOUN
gs-3921	357	9	-	-	PUNCT
gs-3921	357	10	mediated	mediate	VERB
gs-3921	357	11	adrs	adr	NOUN
gs-3921	357	12	further	far	ADV
gs-3921	357	13	exemplifies	exemplify	VERB
gs-3921	357	14	the	the	DET
gs-3921	357	15	precision	precision	NOUN
gs-3921	357	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	357	17	approach	approach	NOUN
gs-3921	357	18	.	.	PUNCT
gs-3921	358	1	identification	identification	NOUN
gs-3921	358	2	of	of	ADP
gs-3921	358	3	high	high	ADJ
gs-3921	358	4	-	-	PUNCT
gs-3921	358	5	risk	risk	NOUN
gs-3921	358	6	alleles	allele	NOUN
gs-3921	358	7	such	such	ADJ
gs-3921	358	8	as	as	ADP
gs-3921	358	9	hlab15:02	hlab15:02	NOUN
gs-3921	358	10	and	and	CCONJ
gs-3921	358	11	hla	hla	PROPN
gs-3921	358	12	-	-	PUNCT
gs-3921	358	13	b57:01	b57:01	PROPN
gs-3921	358	14	has	have	AUX
gs-3921	358	15	enabled	enable	VERB
gs-3921	358	16	the	the	DET
gs-3921	358	17	implementation	implementation	NOUN
gs-3921	358	18	of	of	ADP
gs-3921	358	19	preemptive	preemptive	ADJ
gs-3921	358	20	screening	screen	VERB
gs-3921	358	21	protocols	protocol	NOUN
gs-3921	358	22	,	,	PUNCT
gs-3921	358	23	markedly	markedly	ADV
gs-3921	358	24	reducing	reduce	VERB
gs-3921	358	25	the	the	DET
gs-3921	358	26	incidence	incidence	NOUN
gs-3921	358	27	of	of	ADP
gs-3921	358	28	life	life	NOUN
gs-3921	358	29	-	-	PUNCT
gs-3921	358	30	threatening	threaten	VERB
gs-3921	358	31	hypersensitivity	hypersensitivity	NOUN
gs-3921	358	32	reactions	reaction	NOUN
gs-3921	358	33	.	.	PUNCT
gs-3921	359	1	moreover	moreover	ADV
gs-3921	359	2	,	,	PUNCT
gs-3921	359	3	novel	novel	ADJ
gs-3921	359	4	associations	association	NOUN
gs-3921	359	5	are	be	AUX
gs-3921	359	6	continually	continually	ADV
gs-3921	359	7	being	be	AUX
gs-3921	359	8	discovered	discover	VERB
gs-3921	359	9	,	,	PUNCT
gs-3921	359	10	expanding	expand	VERB
gs-3921	359	11	the	the	DET
gs-3921	359	12	repertoire	repertoire	NOUN
gs-3921	359	13	of	of	ADP
gs-3921	359	14	actionable	actionable	ADJ
gs-3921	359	15	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	359	16	markers	marker	NOUN
gs-3921	359	17	.	.	PUNCT
gs-3921	360	1	for	for	ADP
gs-3921	360	2	example	example	NOUN
gs-3921	360	3	,	,	PUNCT
gs-3921	360	4	emerging	emerge	VERB
gs-3921	360	5	evidence	evidence	NOUN
gs-3921	360	6	implicates	implicate	VERB
gs-3921	360	7	hlaa*31:01	hlaa*31:01	VERB
gs-3921	360	8	in	in	ADP
gs-3921	360	9	carbamazepine	carbamazepine	NOUN
gs-3921	360	10	-	-	PUNCT
gs-3921	360	11	induced	induce	VERB
gs-3921	360	12	hypersensitivity	hypersensitivity	NOUN
gs-3921	360	13	in	in	ADP
gs-3921	360	14	populations	population	NOUN
gs-3921	360	15	beyond	beyond	ADP
gs-3921	360	16	southeast	southeast	PROPN
gs-3921	360	17	asia	asia	PROPN
gs-3921	360	18	,	,	PUNCT
gs-3921	360	19	highlighting	highlight	VERB
gs-3921	360	20	the	the	DET
gs-3921	360	21	necessity	necessity	NOUN
gs-3921	360	22	of	of	ADP
gs-3921	360	23	region	region	NOUN
gs-3921	360	24	-	-	PUNCT
gs-3921	360	25	specific	specific	ADJ
gs-3921	360	26	genetic	genetic	ADJ
gs-3921	360	27	epidemiology	epidemiology	NOUN
gs-3921	360	28	studies	study	NOUN
gs-3921	360	29	.	.	PUNCT
gs-3921	361	1	pharmacodynamic	pharmacodynamic	ADJ
gs-3921	361	2	genetic	genetic	ADJ
gs-3921	361	3	variants	variant	NOUN
gs-3921	361	4	influencing	influence	VERB
gs-3921	361	5	drug	drug	NOUN
gs-3921	361	6	targets	target	NOUN
gs-3921	361	7	and	and	CCONJ
gs-3921	361	8	signaling	signal	VERB
gs-3921	361	9	pathways	pathway	NOUN
gs-3921	361	10	complement	complement	VERB
gs-3921	361	11	metabolic	metabolic	NOUN
gs-3921	361	12	gene	gene	NOUN
gs-3921	361	13	data	datum	NOUN
gs-3921	361	14	,	,	PUNCT
gs-3921	361	15	enriching	enrich	VERB
gs-3921	361	16	the	the	DET
gs-3921	361	17	prediction	prediction	NOUN
gs-3921	361	18	of	of	ADP
gs-3921	361	19	adr	adr	PROPN
gs-3921	361	20	risk	risk	NOUN
gs-3921	361	21	and	and	CCONJ
gs-3921	361	22	therapeutic	therapeutic	ADJ
gs-3921	361	23	response	response	NOUN
gs-3921	361	24	.	.	PUNCT
gs-3921	362	1	polymorphisms	polymorphism	NOUN
gs-3921	362	2	in	in	ADP
gs-3921	362	3	vkorc1	vkorc1	NOUN
gs-3921	362	4	and	and	CCONJ
gs-3921	362	5	cyp2c9	cyp2c9	NOUN
gs-3921	362	6	shape	shape	NOUN
gs-3921	362	7	warfarin	warfarin	NOUN
gs-3921	362	8	dose	dose	NOUN
gs-3921	362	9	requirements	requirement	NOUN
gs-3921	362	10	and	and	CCONJ
gs-3921	362	11	bleeding	bleed	VERB
gs-3921	362	12	risk	risk	NOUN
gs-3921	362	13	,	,	PUNCT
gs-3921	362	14	supporting	support	VERB
gs-3921	362	15	genotype	genotype	NOUN
gs-3921	362	16	-	-	PUNCT
gs-3921	362	17	guided	guide	VERB
gs-3921	362	18	anticoagulation	anticoagulation	NOUN
gs-3921	362	19	initiation	initiation	NOUN
gs-3921	362	20	.	.	PUNCT
gs-3921	363	1	variants	variant	NOUN
gs-3921	363	2	in	in	ADP
gs-3921	363	3	genes	gene	NOUN
gs-3921	363	4	coding	code	VERB
gs-3921	363	5	for	for	ADP
gs-3921	363	6	neurotransmitter	neurotransmitter	NOUN
gs-3921	363	7	receptors	receptor	NOUN
gs-3921	363	8	and	and	CCONJ
gs-3921	363	9	transporters	transporter	NOUN
gs-3921	363	10	modulate	modulate	VERB
gs-3921	363	11	psychotropic	psychotropic	ADJ
gs-3921	363	12	drug	drug	NOUN
gs-3921	363	13	response	response	NOUN
gs-3921	363	14	profiles	profile	NOUN
gs-3921	363	15	,	,	PUNCT
gs-3921	363	16	although	although	SCONJ
gs-3921	363	17	clinical	clinical	ADJ
gs-3921	363	18	translation	translation	NOUN
gs-3921	363	19	remains	remain	VERB
gs-3921	363	20	nascent	nascent	ADJ
gs-3921	363	21	.	.	PUNCT
gs-3921	364	1	collectively	collectively	ADV
gs-3921	364	2	,	,	PUNCT
gs-3921	364	3	these	these	DET
gs-3921	364	4	pharmacodynamic	pharmacodynamic	ADJ
gs-3921	364	5	insights	insight	NOUN
gs-3921	364	6	reinforce	reinforce	VERB
gs-3921	364	7	the	the	DET
gs-3921	364	8	paradigm	paradigm	NOUN
gs-3921	364	9	shift	shift	NOUN
gs-3921	364	10	toward	toward	ADP
gs-3921	364	11	integrating	integrate	VERB
gs-3921	364	12	multilayered	multilayere	VERB
gs-3921	364	13	genetic	genetic	ADJ
gs-3921	364	14	data	datum	NOUN
gs-3921	364	15	into	into	ADP
gs-3921	364	16	clinical	clinical	ADJ
gs-3921	364	17	decision	decision	NOUN
gs-3921	364	18	-	-	PUNCT
gs-3921	364	19	making	make	VERB
gs-3921	364	20	frameworks	framework	NOUN
gs-3921	364	21	.	.	PUNCT
gs-3921	365	1	georgian	georgian	ADJ
gs-3921	365	2	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	365	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	365	4	ტ.	ტ.	VERB
gs-3921	365	5	7	7	NUM
gs-3921	365	6	n	n	PRON
gs-3921	365	7	3	3	NUM
gs-3921	365	8	,	,	PUNCT
gs-3921	365	9	2025	2025	NUM
gs-3921	365	10	239	239	NUM
gs-3921	365	11	barriers	barrier	NOUN
gs-3921	365	12	to	to	ADP
gs-3921	365	13	clinical	clinical	ADJ
gs-3921	365	14	translation	translation	NOUN
gs-3921	365	15	:	:	PUNCT
gs-3921	365	16	systemic	systemic	ADJ
gs-3921	365	17	,	,	PUNCT
gs-3921	365	18	educational	educational	ADJ
gs-3921	365	19	,	,	PUNCT
gs-3921	365	20	and	and	CCONJ
gs-3921	365	21	socioeconomic	socioeconomic	ADJ
gs-3921	365	22	dimensions	dimension	NOUN
gs-3921	365	23	despite	despite	SCONJ
gs-3921	365	24	the	the	DET
gs-3921	365	25	compelling	compelling	ADJ
gs-3921	365	26	evidence	evidence	NOUN
gs-3921	365	27	base	base	NOUN
gs-3921	365	28	,	,	PUNCT
gs-3921	365	29	the	the	DET
gs-3921	365	30	incorporation	incorporation	NOUN
gs-3921	365	31	of	of	ADP
gs-3921	365	32	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	365	33	testing	testing	NOUN
gs-3921	365	34	into	into	ADP
gs-3921	365	35	routine	routine	ADJ
gs-3921	365	36	clinical	clinical	ADJ
gs-3921	365	37	practice	practice	NOUN
gs-3921	365	38	encounters	encounter	VERB
gs-3921	365	39	substantial	substantial	ADJ
gs-3921	365	40	impediments	impediment	NOUN
gs-3921	365	41	.	.	PUNCT
gs-3921	366	1	system	system	NOUN
gs-3921	366	2	-	-	PUNCT
gs-3921	366	3	level	level	NOUN
gs-3921	366	4	barriers	barrier	NOUN
gs-3921	366	5	encompass	encompass	VERB
gs-3921	366	6	limited	limited	ADJ
gs-3921	366	7	infrastructure	infrastructure	NOUN
gs-3921	366	8	for	for	ADP
gs-3921	366	9	genetic	genetic	ADJ
gs-3921	366	10	testing	testing	NOUN
gs-3921	366	11	,	,	PUNCT
gs-3921	366	12	lack	lack	NOUN
gs-3921	366	13	of	of	ADP
gs-3921	366	14	standardized	standardized	ADJ
gs-3921	366	15	reporting	reporting	NOUN
gs-3921	366	16	formats	format	NOUN
gs-3921	366	17	,	,	PUNCT
gs-3921	366	18	and	and	CCONJ
gs-3921	366	19	fragmented	fragmented	ADJ
gs-3921	366	20	integration	integration	NOUN
gs-3921	366	21	with	with	ADP
gs-3921	366	22	electronic	electronic	ADJ
gs-3921	366	23	health	health	NOUN
gs-3921	366	24	record	record	NOUN
gs-3921	366	25	(	(	PUNCT
gs-3921	366	26	ehr	ehr	NOUN
gs-3921	366	27	)	)	PUNCT
gs-3921	366	28	systems	system	NOUN
gs-3921	366	29	.	.	PUNCT
gs-3921	367	1	the	the	DET
gs-3921	367	2	absence	absence	NOUN
gs-3921	367	3	of	of	ADP
gs-3921	367	4	interoperable	interoperable	ADJ
gs-3921	367	5	data	datum	NOUN
gs-3921	367	6	systems	system	NOUN
gs-3921	367	7	undermines	undermine	VERB
gs-3921	367	8	seamless	seamless	ADJ
gs-3921	367	9	dissemination	dissemination	NOUN
gs-3921	367	10	of	of	ADP
gs-3921	367	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	367	12	information	information	NOUN
gs-3921	367	13	at	at	ADP
gs-3921	367	14	the	the	DET
gs-3921	367	15	point	point	NOUN
gs-3921	367	16	of	of	ADP
gs-3921	367	17	care	care	NOUN
gs-3921	367	18	,	,	PUNCT
gs-3921	367	19	hindering	hinder	VERB
gs-3921	367	20	clinician	clinician	NOUN
gs-3921	367	21	access	access	NOUN
gs-3921	367	22	and	and	CCONJ
gs-3921	367	23	utilization	utilization	NOUN
gs-3921	367	24	.	.	PUNCT
gs-3921	368	1	educational	educational	ADJ
gs-3921	368	2	deficits	deficit	NOUN
gs-3921	368	3	among	among	ADP
gs-3921	368	4	healthcare	healthcare	NOUN
gs-3921	368	5	professionals	professional	NOUN
gs-3921	368	6	constitute	constitute	VERB
gs-3921	368	7	a	a	DET
gs-3921	368	8	pervasive	pervasive	ADJ
gs-3921	368	9	challenge	challenge	NOUN
gs-3921	368	10	.	.	PUNCT
gs-3921	369	1	surveys	survey	NOUN
gs-3921	369	2	reveal	reveal	VERB
gs-3921	369	3	that	that	SCONJ
gs-3921	369	4	many	many	ADJ
gs-3921	369	5	clinicians	clinician	NOUN
gs-3921	369	6	possess	possess	VERB
gs-3921	369	7	inadequate	inadequate	ADJ
gs-3921	369	8	knowledge	knowledge	NOUN
gs-3921	369	9	of	of	ADP
gs-3921	369	10	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	369	11	principles	principle	NOUN
gs-3921	369	12	,	,	PUNCT
gs-3921	369	13	interpretation	interpretation	NOUN
gs-3921	369	14	of	of	ADP
gs-3921	369	15	genetic	genetic	ADJ
gs-3921	369	16	test	test	NOUN
gs-3921	369	17	results	result	NOUN
gs-3921	369	18	,	,	PUNCT
gs-3921	369	19	and	and	CCONJ
gs-3921	369	20	application	application	NOUN
gs-3921	369	21	in	in	ADP
gs-3921	369	22	therapeutic	therapeutic	ADJ
gs-3921	369	23	decisionmaking	decisionmaking	NOUN
gs-3921	369	24	.	.	PUNCT
gs-3921	370	1	the	the	DET
gs-3921	370	2	paucity	paucity	NOUN
gs-3921	370	3	of	of	ADP
gs-3921	370	4	formal	formal	ADJ
gs-3921	370	5	training	training	NOUN
gs-3921	370	6	during	during	ADP
gs-3921	370	7	undergraduate	undergraduate	NOUN
gs-3921	370	8	and	and	CCONJ
gs-3921	370	9	postgraduate	postgraduate	NOUN
gs-3921	370	10	curricula	curricula	NOUN
gs-3921	370	11	,	,	PUNCT
gs-3921	370	12	coupled	couple	VERB
gs-3921	370	13	with	with	ADP
gs-3921	370	14	insufficient	insufficient	ADJ
gs-3921	370	15	continuing	continue	VERB
gs-3921	370	16	medical	medical	ADJ
gs-3921	370	17	education	education	NOUN
gs-3921	370	18	opportunities	opportunity	NOUN
gs-3921	370	19	,	,	PUNCT
gs-3921	370	20	constrains	constrain	VERB
gs-3921	370	21	clinician	clinician	ADJ
gs-3921	370	22	confidence	confidence	NOUN
gs-3921	370	23	and	and	CCONJ
gs-3921	370	24	engagement	engagement	NOUN
gs-3921	370	25	.	.	PUNCT
gs-3921	371	1	interdisciplinary	interdisciplinary	ADJ
gs-3921	371	2	educational	educational	ADJ
gs-3921	371	3	initiatives	initiative	NOUN
gs-3921	371	4	involving	involve	VERB
gs-3921	371	5	pharmacists	pharmacist	NOUN
gs-3921	371	6	,	,	PUNCT
gs-3921	371	7	genetic	genetic	ADJ
gs-3921	371	8	counselors	counselor	NOUN
gs-3921	371	9	,	,	PUNCT
gs-3921	371	10	and	and	CCONJ
gs-3921	371	11	physicians	physician	NOUN
gs-3921	371	12	have	have	AUX
gs-3921	371	13	demonstrated	demonstrate	VERB
gs-3921	371	14	potential	potential	ADJ
gs-3921	371	15	in	in	ADP
gs-3921	371	16	enhancing	enhance	VERB
gs-3921	371	17	knowledge	knowledge	NOUN
gs-3921	371	18	and	and	CCONJ
gs-3921	371	19	promoting	promote	VERB
gs-3921	371	20	collaborative	collaborative	ADJ
gs-3921	371	21	care	care	NOUN
gs-3921	371	22	models	model	NOUN
gs-3921	371	23	.	.	PUNCT
gs-3921	372	1	economic	economic	ADJ
gs-3921	372	2	considerations	consideration	NOUN
gs-3921	372	3	also	also	ADV
gs-3921	372	4	weigh	weigh	VERB
gs-3921	372	5	heavily	heavily	ADV
gs-3921	372	6	on	on	ADP
gs-3921	372	7	adoption	adoption	NOUN
gs-3921	372	8	rates	rate	NOUN
gs-3921	372	9	.	.	PUNCT
gs-3921	373	1	the	the	DET
gs-3921	373	2	cost	cost	NOUN
gs-3921	373	3	of	of	ADP
gs-3921	373	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	373	5	testing	testing	NOUN
gs-3921	373	6	,	,	PUNCT
gs-3921	373	7	although	although	SCONJ
gs-3921	373	8	decreasing	decrease	VERB
gs-3921	373	9	with	with	ADP
gs-3921	373	10	technological	technological	ADJ
gs-3921	373	11	advances	advance	NOUN
gs-3921	373	12	,	,	PUNCT
gs-3921	373	13	remains	remain	VERB
gs-3921	373	14	a	a	DET
gs-3921	373	15	significant	significant	ADJ
gs-3921	373	16	barrier	barrier	NOUN
gs-3921	373	17	,	,	PUNCT
gs-3921	373	18	particularly	particularly	ADV
gs-3921	373	19	in	in	ADP
gs-3921	373	20	publicly	publicly	ADV
gs-3921	373	21	funded	fund	VERB
gs-3921	373	22	health	health	NOUN
gs-3921	373	23	systems	system	NOUN
gs-3921	373	24	with	with	ADP
gs-3921	373	25	constrained	constrained	ADJ
gs-3921	373	26	budgets	budget	NOUN
gs-3921	373	27	.	.	PUNCT
gs-3921	374	1	the	the	DET
gs-3921	374	2	absence	absence	NOUN
gs-3921	374	3	of	of	ADP
gs-3921	374	4	universally	universally	ADV
gs-3921	374	5	accepted	accept	VERB
gs-3921	374	6	reimbursement	reimbursement	NOUN
gs-3921	374	7	policies	policy	NOUN
gs-3921	374	8	and	and	CCONJ
gs-3921	374	9	the	the	DET
gs-3921	374	10	variability	variability	NOUN
gs-3921	374	11	in	in	ADP
gs-3921	374	12	payer	payer	NOUN
gs-3921	374	13	coverage	coverage	NOUN
gs-3921	374	14	contribute	contribute	VERB
gs-3921	374	15	to	to	ADP
gs-3921	374	16	inequitable	inequitable	ADJ
gs-3921	374	17	access	access	NOUN
gs-3921	374	18	.	.	PUNCT
gs-3921	375	1	furthermore	furthermore	ADV
gs-3921	375	2	,	,	PUNCT
gs-3921	375	3	robust	robust	ADJ
gs-3921	375	4	health	health	NOUN
gs-3921	375	5	economic	economic	ADJ
gs-3921	375	6	evaluations	evaluation	NOUN
gs-3921	375	7	are	be	AUX
gs-3921	375	8	lacking	lack	VERB
gs-3921	375	9	for	for	ADP
gs-3921	375	10	many	many	ADJ
gs-3921	375	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	375	12	applications	application	NOUN
gs-3921	375	13	,	,	PUNCT
gs-3921	375	14	impeding	impede	VERB
gs-3921	375	15	evidence	evidence	NOUN
gs-3921	375	16	-	-	PUNCT
gs-3921	375	17	based	base	VERB
gs-3921	375	18	policy	policy	NOUN
gs-3921	375	19	development	development	NOUN
gs-3921	375	20	.	.	PUNCT
gs-3921	376	1	socioeconomic	socioeconomic	ADJ
gs-3921	376	2	and	and	CCONJ
gs-3921	376	3	cultural	cultural	ADJ
gs-3921	376	4	factors	factor	NOUN
gs-3921	376	5	influence	influence	VERB
gs-3921	376	6	patient	patient	ADJ
gs-3921	376	7	acceptance	acceptance	NOUN
gs-3921	376	8	and	and	CCONJ
gs-3921	376	9	participation	participation	NOUN
gs-3921	376	10	in	in	ADP
gs-3921	376	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	376	12	testing	testing	NOUN
gs-3921	376	13	.	.	PUNCT
gs-3921	377	1	concerns	concern	NOUN
gs-3921	377	2	about	about	ADP
gs-3921	377	3	genetic	genetic	ADJ
gs-3921	377	4	privacy	privacy	NOUN
gs-3921	377	5	,	,	PUNCT
gs-3921	377	6	potential	potential	ADJ
gs-3921	377	7	discrimination	discrimination	NOUN
gs-3921	377	8	,	,	PUNCT
gs-3921	377	9	and	and	CCONJ
gs-3921	377	10	misunderstanding	misunderstanding	NOUN
gs-3921	377	11	of	of	ADP
gs-3921	377	12	genetic	genetic	ADJ
gs-3921	377	13	risk	risk	NOUN
gs-3921	377	14	contribute	contribute	VERB
gs-3921	377	15	to	to	ADP
gs-3921	377	16	reluctance	reluctance	NOUN
gs-3921	377	17	in	in	ADP
gs-3921	377	18	some	some	DET
gs-3921	377	19	populations	population	NOUN
gs-3921	377	20	.	.	PUNCT
gs-3921	378	1	health	health	NOUN
gs-3921	378	2	literacy	literacy	NOUN
gs-3921	378	3	disparities	disparity	NOUN
gs-3921	378	4	exacerbate	exacerbate	VERB
gs-3921	378	5	these	these	DET
gs-3921	378	6	issues	issue	NOUN
gs-3921	378	7	,	,	PUNCT
gs-3921	378	8	necessitating	necessitate	VERB
gs-3921	378	9	culturally	culturally	ADV
gs-3921	378	10	sensitive	sensitive	ADJ
gs-3921	378	11	educational	educational	ADJ
gs-3921	378	12	interventions	intervention	NOUN
gs-3921	378	13	and	and	CCONJ
gs-3921	378	14	equitable	equitable	ADJ
gs-3921	378	15	access	access	NOUN
gs-3921	378	16	to	to	ADP
gs-3921	378	17	genetic	genetic	ADJ
gs-3921	378	18	counseling	counseling	NOUN
gs-3921	378	19	services	service	NOUN
gs-3921	378	20	.	.	PUNCT
gs-3921	379	1	community	community	NOUN
gs-3921	379	2	engagement	engagement	NOUN
gs-3921	379	3	and	and	CCONJ
gs-3921	379	4	participatory	participatory	ADJ
gs-3921	379	5	research	research	NOUN
gs-3921	379	6	approaches	approach	NOUN
gs-3921	379	7	are	be	AUX
gs-3921	379	8	critical	critical	ADJ
gs-3921	379	9	to	to	ADP
gs-3921	379	10	building	build	VERB
gs-3921	379	11	trust	trust	NOUN
gs-3921	379	12	and	and	CCONJ
gs-3921	379	13	tailoring	tailor	VERB
gs-3921	379	14	implementation	implementation	NOUN
gs-3921	379	15	strategies	strategy	NOUN
gs-3921	379	16	.	.	PUNCT
gs-3921	380	1	innovations	innovation	NOUN
gs-3921	380	2	in	in	ADP
gs-3921	380	3	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	380	4	:	:	PUNCT
gs-3921	380	5	from	from	ADP
gs-3921	380	6	passive	passive	ADJ
gs-3921	380	7	surveillance	surveillance	NOUN
gs-3921	380	8	to	to	ADP
gs-3921	380	9	integrated	integrate	VERB
gs-3921	380	10	precision	precision	NOUN
gs-3921	380	11	monitoring	monitoring	NOUN
gs-3921	380	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	380	13	,	,	PUNCT
gs-3921	380	14	historically	historically	ADV
gs-3921	380	15	reliant	reliant	ADJ
gs-3921	380	16	on	on	ADP
gs-3921	380	17	spontaneous	spontaneous	ADJ
gs-3921	380	18	adverse	adverse	ADJ
gs-3921	380	19	event	event	NOUN
gs-3921	380	20	reporting	reporting	NOUN
gs-3921	380	21	,	,	PUNCT
gs-3921	380	22	is	be	AUX
gs-3921	380	23	undergoing	undergo	VERB
gs-3921	380	24	a	a	DET
gs-3921	380	25	paradigm	paradigm	NOUN
gs-3921	380	26	shift	shift	NOUN
gs-3921	380	27	towards	towards	ADP
gs-3921	380	28	proactive	proactive	ADJ
gs-3921	380	29	,	,	PUNCT
gs-3921	380	30	data	data	NOUN
gs-3921	380	31	-	-	PUNCT
gs-3921	380	32	driven	drive	VERB
gs-3921	380	33	surveillance	surveillance	NOUN
gs-3921	380	34	systems	system	NOUN
gs-3921	380	35	augmented	augment	VERB
gs-3921	380	36	by	by	ADP
gs-3921	380	37	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	380	38	insights	insight	NOUN
gs-3921	380	39	.	.	PUNCT
gs-3921	381	1	traditional	traditional	ADJ
gs-3921	381	2	reporting	reporting	NOUN
gs-3921	381	3	systems	system	NOUN
gs-3921	381	4	suffer	suffer	VERB
gs-3921	381	5	from	from	ADP
gs-3921	381	6	welldocumented	welldocumented	ADJ
gs-3921	381	7	limitations	limitation	NOUN
gs-3921	381	8	including	include	VERB
gs-3921	381	9	underreporting	underreporte	VERB
gs-3921	381	10	,	,	PUNCT
gs-3921	381	11	delayed	delay	VERB
gs-3921	381	12	signal	signal	ADJ
gs-3921	381	13	detection	detection	NOUN
gs-3921	381	14	,	,	PUNCT
gs-3921	381	15	and	and	CCONJ
gs-3921	381	16	bias	bias	NOUN
gs-3921	381	17	.	.	PUNCT
gs-3921	382	1	integration	integration	NOUN
gs-3921	382	2	of	of	ADP
gs-3921	382	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	382	4	data	datum	NOUN
gs-3921	382	5	enables	enable	VERB
gs-3921	382	6	stratification	stratification	NOUN
gs-3921	382	7	of	of	ADP
gs-3921	382	8	safety	safety	NOUN
gs-3921	382	9	signals	signal	NOUN
gs-3921	382	10	by	by	ADP
gs-3921	382	11	genetic	genetic	ADJ
gs-3921	382	12	risk	risk	NOUN
gs-3921	382	13	,	,	PUNCT
gs-3921	382	14	refining	refine	VERB
gs-3921	382	15	the	the	DET
gs-3921	382	16	specificity	specificity	NOUN
gs-3921	382	17	and	and	CCONJ
gs-3921	382	18	clinical	clinical	ADJ
gs-3921	382	19	relevance	relevance	NOUN
gs-3921	382	20	of	of	ADP
gs-3921	382	21	detected	detect	VERB
gs-3921	382	22	associations	association	NOUN
gs-3921	382	23	.	.	PUNCT
gs-3921	383	1	georgian	georgian	ADJ
gs-3921	383	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	383	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	383	4	ტ.	ტ.	VERB
gs-3921	383	5	7	7	NUM
gs-3921	383	6	n	n	DET
gs-3921	383	7	3	3	NUM
gs-3921	383	8	,	,	PUNCT
gs-3921	383	9	2025	2025	NUM
gs-3921	383	10	240	240	NUM
gs-3921	383	11	active	active	ADJ
gs-3921	383	12	surveillance	surveillance	NOUN
gs-3921	383	13	methodologies	methodology	NOUN
gs-3921	383	14	leveraging	leverage	VERB
gs-3921	383	15	real	real	ADJ
gs-3921	383	16	-	-	PUNCT
gs-3921	383	17	world	world	NOUN
gs-3921	383	18	data	datum	NOUN
gs-3921	383	19	(	(	PUNCT
gs-3921	383	20	rwd	rwd	NOUN
gs-3921	383	21	)	)	PUNCT
gs-3921	383	22	sources	source	NOUN
gs-3921	383	23	such	such	ADJ
gs-3921	383	24	as	as	ADP
gs-3921	383	25	ehrs	ehrs	PROPN
gs-3921	383	26	,	,	PUNCT
gs-3921	383	27	claims	claim	VERB
gs-3921	383	28	databases	database	NOUN
gs-3921	383	29	,	,	PUNCT
gs-3921	383	30	and	and	CCONJ
gs-3921	383	31	patient	patient	ADJ
gs-3921	383	32	registries	registry	NOUN
gs-3921	383	33	facilitate	facilitate	VERB
gs-3921	383	34	continuous	continuous	ADJ
gs-3921	383	35	monitoring	monitoring	NOUN
gs-3921	383	36	of	of	ADP
gs-3921	383	37	drug	drug	NOUN
gs-3921	383	38	safety	safety	NOUN
gs-3921	383	39	profiles	profile	NOUN
gs-3921	383	40	.	.	PUNCT
gs-3921	384	1	the	the	DET
gs-3921	384	2	application	application	NOUN
gs-3921	384	3	of	of	ADP
gs-3921	384	4	natural	natural	ADJ
gs-3921	384	5	language	language	NOUN
gs-3921	384	6	processing	processing	NOUN
gs-3921	384	7	and	and	CCONJ
gs-3921	384	8	machine	machine	NOUN
gs-3921	384	9	learning	learn	VERB
gs-3921	384	10	algorithms	algorithms	NOUN
gs-3921	384	11	enhances	enhance	VERB
gs-3921	384	12	signal	signal	ADJ
gs-3921	384	13	detection	detection	NOUN
gs-3921	384	14	capabilities	capability	NOUN
gs-3921	384	15	by	by	ADP
gs-3921	384	16	mining	mine	VERB
gs-3921	384	17	unstructured	unstructured	ADJ
gs-3921	384	18	clinical	clinical	ADJ
gs-3921	384	19	narratives	narrative	NOUN
gs-3921	384	20	and	and	CCONJ
gs-3921	384	21	identifying	identify	VERB
gs-3921	384	22	novel	novel	ADJ
gs-3921	384	23	gene	gene	NOUN
gs-3921	384	24	-	-	PUNCT
gs-3921	384	25	drug	drug	NOUN
gs-3921	384	26	interactions	interaction	NOUN
gs-3921	384	27	.	.	PUNCT
gs-3921	385	1	initiatives	initiative	NOUN
gs-3921	385	2	such	such	ADJ
gs-3921	385	3	as	as	ADP
gs-3921	385	4	the	the	DET
gs-3921	385	5	fda	fda	PROPN
gs-3921	385	6	sentinel	sentinel	PROPN
gs-3921	385	7	system	system	NOUN
gs-3921	385	8	exemplify	exemplify	VERB
gs-3921	385	9	large	large	ADJ
gs-3921	385	10	-	-	PUNCT
gs-3921	385	11	scale	scale	NOUN
gs-3921	385	12	implementations	implementation	NOUN
gs-3921	385	13	of	of	ADP
gs-3921	385	14	such	such	ADJ
gs-3921	385	15	approaches	approach	NOUN
gs-3921	385	16	,	,	PUNCT
gs-3921	385	17	incorporating	incorporate	VERB
gs-3921	385	18	genetic	genetic	ADJ
gs-3921	385	19	data	datum	NOUN
gs-3921	385	20	to	to	PART
gs-3921	385	21	monitor	monitor	VERB
gs-3921	385	22	and	and	CCONJ
gs-3921	385	23	mitigate	mitigate	VERB
gs-3921	385	24	adrs	adr	NOUN
gs-3921	385	25	effectively	effectively	ADV
gs-3921	385	26	.	.	PUNCT
gs-3921	386	1	patient	patient	NOUN
gs-3921	386	2	-	-	PUNCT
gs-3921	386	3	centered	center	VERB
gs-3921	386	4	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	386	5	initiatives	initiative	NOUN
gs-3921	386	6	have	have	AUX
gs-3921	386	7	emerged	emerge	VERB
gs-3921	386	8	,	,	PUNCT
gs-3921	386	9	utilizing	utilize	VERB
gs-3921	386	10	mobile	mobile	ADJ
gs-3921	386	11	health	health	NOUN
gs-3921	386	12	technologies	technology	NOUN
gs-3921	386	13	and	and	CCONJ
gs-3921	386	14	digital	digital	ADJ
gs-3921	386	15	platforms	platform	NOUN
gs-3921	386	16	to	to	PART
gs-3921	386	17	enable	enable	VERB
gs-3921	386	18	real	real	ADJ
gs-3921	386	19	-	-	PUNCT
gs-3921	386	20	time	time	NOUN
gs-3921	386	21	adverse	adverse	ADJ
gs-3921	386	22	event	event	NOUN
gs-3921	386	23	reporting	report	VERB
gs-3921	386	24	and	and	CCONJ
gs-3921	386	25	monitoring	monitoring	NOUN
gs-3921	386	26	.	.	PUNCT
gs-3921	387	1	wearable	wearable	ADJ
gs-3921	387	2	biosensors	biosensor	NOUN
gs-3921	387	3	capture	capture	VERB
gs-3921	387	4	physiological	physiological	ADJ
gs-3921	387	5	parameters	parameter	NOUN
gs-3921	387	6	indicative	indicative	ADJ
gs-3921	387	7	of	of	ADP
gs-3921	387	8	drug	drug	NOUN
gs-3921	387	9	toxicity	toxicity	NOUN
gs-3921	387	10	,	,	PUNCT
gs-3921	387	11	while	while	SCONJ
gs-3921	387	12	patient	patient	NOUN
gs-3921	387	13	-	-	PUNCT
gs-3921	387	14	reported	report	VERB
gs-3921	387	15	outcome	outcome	NOUN
gs-3921	387	16	measures	measure	NOUN
gs-3921	387	17	enrich	enrich	VERB
gs-3921	387	18	safety	safety	NOUN
gs-3921	387	19	data	datum	NOUN
gs-3921	387	20	.	.	PUNCT
gs-3921	388	1	these	these	DET
gs-3921	388	2	technologies	technology	NOUN
gs-3921	388	3	empower	empower	NOUN
gs-3921	388	4	patients	patient	NOUN
gs-3921	388	5	as	as	ADP
gs-3921	388	6	active	active	ADJ
gs-3921	388	7	participants	participant	NOUN
gs-3921	388	8	in	in	ADP
gs-3921	388	9	medication	medication	NOUN
gs-3921	388	10	safety	safety	NOUN
gs-3921	388	11	,	,	PUNCT
gs-3921	388	12	fostering	foster	VERB
gs-3921	388	13	engagement	engagement	NOUN
gs-3921	388	14	and	and	CCONJ
gs-3921	388	15	timely	timely	ADJ
gs-3921	388	16	intervention	intervention	NOUN
gs-3921	388	17	.	.	PUNCT
gs-3921	389	1	however	however	ADV
gs-3921	389	2	,	,	PUNCT
gs-3921	389	3	challenges	challenge	NOUN
gs-3921	389	4	persist	persist	VERB
gs-3921	389	5	in	in	ADP
gs-3921	389	6	standardizing	standardize	VERB
gs-3921	389	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	389	8	data	datum	NOUN
gs-3921	389	9	capture	capture	NOUN
gs-3921	389	10	within	within	ADP
gs-3921	389	11	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	389	12	frameworks	framework	NOUN
gs-3921	389	13	,	,	PUNCT
gs-3921	389	14	ensuring	ensure	VERB
gs-3921	389	15	data	datum	NOUN
gs-3921	389	16	quality	quality	NOUN
gs-3921	389	17	,	,	PUNCT
gs-3921	389	18	and	and	CCONJ
gs-3921	389	19	safeguarding	safeguard	VERB
gs-3921	389	20	patient	patient	ADJ
gs-3921	389	21	privacy	privacy	NOUN
gs-3921	389	22	.	.	PUNCT
gs-3921	390	1	harmonized	harmonized	ADJ
gs-3921	390	2	ontologies	ontology	NOUN
gs-3921	390	3	and	and	CCONJ
gs-3921	390	4	data	datum	NOUN
gs-3921	390	5	standards	standard	NOUN
gs-3921	390	6	are	be	AUX
gs-3921	390	7	essential	essential	ADJ
gs-3921	390	8	for	for	ADP
gs-3921	390	9	interoperability	interoperability	NOUN
gs-3921	390	10	and	and	CCONJ
gs-3921	390	11	meaningful	meaningful	ADJ
gs-3921	390	12	data	datum	NOUN
gs-3921	390	13	aggregation	aggregation	NOUN
gs-3921	390	14	.	.	PUNCT
gs-3921	391	1	ethical	ethical	ADJ
gs-3921	391	2	frameworks	framework	NOUN
gs-3921	391	3	guiding	guide	VERB
gs-3921	391	4	data	datum	NOUN
gs-3921	391	5	use	use	NOUN
gs-3921	391	6	and	and	CCONJ
gs-3921	391	7	sharing	sharing	NOUN
gs-3921	391	8	must	must	AUX
gs-3921	391	9	balance	balance	VERB
gs-3921	391	10	public	public	ADJ
gs-3921	391	11	health	health	NOUN
gs-3921	391	12	benefits	benefit	NOUN
gs-3921	391	13	with	with	ADP
gs-3921	391	14	individual	individual	ADJ
gs-3921	391	15	rights	right	NOUN
gs-3921	391	16	.	.	PUNCT
gs-3921	392	1	technological	technological	ADJ
gs-3921	392	2	innovations	innovation	NOUN
gs-3921	392	3	:	:	PUNCT
gs-3921	392	4	digital	digital	ADJ
gs-3921	392	5	health	health	NOUN
gs-3921	392	6	and	and	CCONJ
gs-3921	392	7	beyond	beyond	ADP
gs-3921	392	8	digital	digital	ADJ
gs-3921	392	9	health	health	NOUN
gs-3921	392	10	technologies	technology	NOUN
gs-3921	392	11	are	be	AUX
gs-3921	392	12	rapidly	rapidly	ADV
gs-3921	392	13	transforming	transform	VERB
gs-3921	392	14	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	392	15	implementation	implementation	NOUN
gs-3921	392	16	and	and	CCONJ
gs-3921	392	17	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	392	18	.	.	PUNCT
gs-3921	393	1	mobile	mobile	ADJ
gs-3921	393	2	applications	application	NOUN
gs-3921	393	3	facilitate	facilitate	VERB
gs-3921	393	4	patient	patient	ADJ
gs-3921	393	5	engagement	engagement	NOUN
gs-3921	393	6	,	,	PUNCT
gs-3921	393	7	education	education	NOUN
gs-3921	393	8	,	,	PUNCT
gs-3921	393	9	and	and	CCONJ
gs-3921	393	10	adverse	adverse	ADJ
gs-3921	393	11	event	event	NOUN
gs-3921	393	12	reporting	report	VERB
gs-3921	393	13	.	.	PUNCT
gs-3921	394	1	wearable	wearable	ADJ
gs-3921	394	2	devices	device	NOUN
gs-3921	394	3	capture	capture	VERB
gs-3921	394	4	continuous	continuous	ADJ
gs-3921	394	5	physiological	physiological	ADJ
gs-3921	394	6	data	datum	NOUN
gs-3921	394	7	,	,	PUNCT
gs-3921	394	8	enabling	enable	VERB
gs-3921	394	9	early	early	ADJ
gs-3921	394	10	detection	detection	NOUN
gs-3921	394	11	of	of	ADP
gs-3921	394	12	toxicities	toxicity	NOUN
gs-3921	394	13	and	and	CCONJ
gs-3921	394	14	personalized	personalized	ADJ
gs-3921	394	15	interventions	intervention	NOUN
gs-3921	394	16	.	.	PUNCT
gs-3921	395	1	blockchain	blockchain	PROPN
gs-3921	395	2	technology	technology	PROPN
gs-3921	395	3	offers	offer	VERB
gs-3921	395	4	promising	promise	VERB
gs-3921	395	5	solutions	solution	NOUN
gs-3921	395	6	for	for	ADP
gs-3921	395	7	secure	secure	ADJ
gs-3921	395	8	,	,	PUNCT
gs-3921	395	9	decentralized	decentralized	ADJ
gs-3921	395	10	management	management	NOUN
gs-3921	395	11	of	of	ADP
gs-3921	395	12	genetic	genetic	ADJ
gs-3921	395	13	and	and	CCONJ
gs-3921	395	14	health	health	NOUN
gs-3921	395	15	data	datum	NOUN
gs-3921	395	16	,	,	PUNCT
gs-3921	395	17	enhancing	enhance	VERB
gs-3921	395	18	patient	patient	NOUN
gs-3921	395	19	control	control	NOUN
gs-3921	395	20	,	,	PUNCT
gs-3921	395	21	data	datum	NOUN
gs-3921	395	22	integrity	integrity	NOUN
gs-3921	395	23	,	,	PUNCT
gs-3921	395	24	and	and	CCONJ
gs-3921	395	25	interoperability	interoperability	NOUN
gs-3921	395	26	.	.	PUNCT
gs-3921	396	1	artificial	artificial	ADJ
gs-3921	396	2	intelligence	intelligence	NOUN
gs-3921	396	3	algorithms	algorithm	NOUN
gs-3921	396	4	enhance	enhance	VERB
gs-3921	396	5	data	datum	NOUN
gs-3921	396	6	analytics	analytic	NOUN
gs-3921	396	7	,	,	PUNCT
gs-3921	396	8	enabling	enable	VERB
gs-3921	396	9	predictive	predictive	ADJ
gs-3921	396	10	modeling	modeling	NOUN
gs-3921	396	11	and	and	CCONJ
gs-3921	396	12	clinical	clinical	ADJ
gs-3921	396	13	decision	decision	NOUN
gs-3921	396	14	support	support	NOUN
gs-3921	396	15	.	.	PUNCT
gs-3921	397	1	successful	successful	ADJ
gs-3921	397	2	integration	integration	NOUN
gs-3921	397	3	requires	require	VERB
gs-3921	397	4	addressing	address	VERB
gs-3921	397	5	challenges	challenge	NOUN
gs-3921	397	6	of	of	ADP
gs-3921	397	7	validation	validation	NOUN
gs-3921	397	8	,	,	PUNCT
gs-3921	397	9	user	user	NOUN
gs-3921	397	10	acceptance	acceptance	NOUN
gs-3921	397	11	,	,	PUNCT
gs-3921	397	12	regulatory	regulatory	ADJ
gs-3921	397	13	oversight	oversight	NOUN
gs-3921	397	14	,	,	PUNCT
gs-3921	397	15	and	and	CCONJ
gs-3921	397	16	equitable	equitable	ADJ
gs-3921	397	17	access	access	NOUN
gs-3921	397	18	.	.	PUNCT
gs-3921	398	1	cross	cross	ADJ
gs-3921	398	2	-	-	ADJ
gs-3921	398	3	sector	sector	ADJ
gs-3921	398	4	collaboration	collaboration	NOUN
gs-3921	398	5	and	and	CCONJ
gs-3921	398	6	adaptive	adaptive	ADJ
gs-3921	398	7	governance	governance	NOUN
gs-3921	398	8	frameworks	framework	NOUN
gs-3921	398	9	are	be	AUX
gs-3921	398	10	vital	vital	ADJ
gs-3921	398	11	.	.	PUNCT
gs-3921	399	1	global	global	ADJ
gs-3921	399	2	perspectives	perspective	NOUN
gs-3921	399	3	and	and	CCONJ
gs-3921	399	4	policy	policy	NOUN
gs-3921	399	5	implications	implication	NOUN
gs-3921	399	6	the	the	DET
gs-3921	399	7	global	global	ADJ
gs-3921	399	8	implementation	implementation	NOUN
gs-3921	399	9	of	of	ADP
gs-3921	399	10	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	399	11	and	and	CCONJ
gs-3921	399	12	advanced	advanced	ADJ
gs-3921	399	13	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	399	14	necessitates	necessitate	VERB
gs-3921	399	15	tailored	tailor	VERB
gs-3921	399	16	strategies	strategy	NOUN
gs-3921	399	17	responsive	responsive	ADJ
gs-3921	399	18	to	to	ADP
gs-3921	399	19	diverse	diverse	VERB
gs-3921	399	20	healthcare	healthcare	NOUN
gs-3921	399	21	infrastructures	infrastructure	NOUN
gs-3921	399	22	,	,	PUNCT
gs-3921	399	23	genetic	genetic	ADJ
gs-3921	399	24	backgrounds	background	NOUN
gs-3921	399	25	,	,	PUNCT
gs-3921	399	26	and	and	CCONJ
gs-3921	399	27	sociocultural	sociocultural	ADJ
gs-3921	399	28	contexts	contexts	NOUN
gs-3921	399	29	.	.	PUNCT
gs-3921	400	1	capacity	capacity	NOUN
gs-3921	400	2	building	build	VERB
gs-3921	400	3	in	in	ADP
gs-3921	400	4	lowand	lowand	ADJ
gs-3921	400	5	middle	middle	ADJ
gs-3921	400	6	-	-	PUNCT
gs-3921	400	7	income	income	NOUN
gs-3921	400	8	countries	country	NOUN
gs-3921	400	9	through	through	ADP
gs-3921	400	10	training	training	NOUN
gs-3921	400	11	,	,	PUNCT
gs-3921	400	12	technology	technology	NOUN
gs-3921	400	13	transfer	transfer	NOUN
gs-3921	400	14	,	,	PUNCT
gs-3921	400	15	and	and	CCONJ
gs-3921	400	16	infrastructure	infrastructure	NOUN
gs-3921	400	17	development	development	NOUN
gs-3921	400	18	is	be	AUX
gs-3921	400	19	critical	critical	ADJ
gs-3921	400	20	to	to	PART
gs-3921	400	21	equitable	equitable	VERB
gs-3921	400	22	global	global	ADJ
gs-3921	400	23	health	health	NOUN
gs-3921	400	24	impact	impact	NOUN
gs-3921	400	25	.	.	PUNCT
gs-3921	401	1	georgian	georgian	ADJ
gs-3921	401	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	401	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	401	4	ტ.	ტ.	VERB
gs-3921	401	5	7	7	NUM
gs-3921	401	6	n	n	PRON
gs-3921	401	7	3	3	NUM
gs-3921	401	8	,	,	PUNCT
gs-3921	401	9	2025	2025	NUM
gs-3921	401	10	241	241	NUM
gs-3921	401	11	international	international	ADJ
gs-3921	401	12	collaboration	collaboration	NOUN
gs-3921	401	13	fosters	foster	VERB
gs-3921	401	14	data	datum	NOUN
gs-3921	401	15	sharing	sharing	NOUN
gs-3921	401	16	,	,	PUNCT
gs-3921	401	17	standardization	standardization	NOUN
gs-3921	401	18	of	of	ADP
gs-3921	401	19	testing	testing	NOUN
gs-3921	401	20	and	and	CCONJ
gs-3921	401	21	reporting	reporting	NOUN
gs-3921	401	22	,	,	PUNCT
gs-3921	401	23	and	and	CCONJ
gs-3921	401	24	harmonization	harmonization	NOUN
gs-3921	401	25	of	of	ADP
gs-3921	401	26	regulatory	regulatory	ADJ
gs-3921	401	27	frameworks	framework	NOUN
gs-3921	401	28	.	.	PUNCT
gs-3921	402	1	public	public	ADJ
gs-3921	402	2	-	-	PUNCT
gs-3921	402	3	private	private	ADJ
gs-3921	402	4	partnerships	partnership	NOUN
gs-3921	402	5	and	and	CCONJ
gs-3921	402	6	stakeholder	stakeholder	NOUN
gs-3921	402	7	engagement	engagement	NOUN
gs-3921	402	8	accelerate	accelerate	NOUN
gs-3921	402	9	innovation	innovation	NOUN
gs-3921	402	10	and	and	CCONJ
gs-3921	402	11	dissemination	dissemination	NOUN
gs-3921	402	12	.	.	PUNCT
gs-3921	403	1	policy	policy	NOUN
gs-3921	403	2	development	development	NOUN
gs-3921	403	3	must	must	AUX
gs-3921	403	4	balance	balance	VERB
gs-3921	403	5	innovation	innovation	NOUN
gs-3921	403	6	with	with	ADP
gs-3921	403	7	ethical	ethical	ADJ
gs-3921	403	8	safeguards	safeguard	NOUN
gs-3921	403	9	,	,	PUNCT
gs-3921	403	10	patient	patient	ADJ
gs-3921	403	11	rights	right	NOUN
gs-3921	403	12	,	,	PUNCT
gs-3921	403	13	and	and	CCONJ
gs-3921	403	14	health	health	NOUN
gs-3921	403	15	equity	equity	NOUN
gs-3921	403	16	.	.	PUNCT
gs-3921	404	1	multi	multi	ADJ
gs-3921	404	2	-	-	ADJ
gs-3921	404	3	stakeholder	stakeholder	ADJ
gs-3921	404	4	dialogues	dialogue	NOUN
gs-3921	404	5	and	and	CCONJ
gs-3921	404	6	evidence	evidence	NOUN
gs-3921	404	7	-	-	PUNCT
gs-3921	404	8	based	base	VERB
gs-3921	404	9	guidelines	guideline	NOUN
gs-3921	404	10	support	support	NOUN
gs-3921	404	11	sustainable	sustainable	ADJ
gs-3921	404	12	,	,	PUNCT
gs-3921	404	13	responsible	responsible	ADJ
gs-3921	404	14	integration	integration	NOUN
gs-3921	404	15	.	.	PUNCT
gs-3921	405	1	the	the	DET
gs-3921	405	2	integration	integration	NOUN
gs-3921	405	3	of	of	ADP
gs-3921	405	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	405	5	into	into	ADP
gs-3921	405	6	clinical	clinical	ADJ
gs-3921	405	7	practice	practice	NOUN
gs-3921	405	8	represents	represent	VERB
gs-3921	405	9	a	a	DET
gs-3921	405	10	paradigm	paradigm	NOUN
gs-3921	405	11	shift	shift	NOUN
gs-3921	405	12	in	in	ADP
gs-3921	405	13	the	the	DET
gs-3921	405	14	personalization	personalization	NOUN
gs-3921	405	15	of	of	ADP
gs-3921	405	16	medicine	medicine	NOUN
gs-3921	405	17	,	,	PUNCT
gs-3921	405	18	with	with	ADP
gs-3921	405	19	the	the	DET
gs-3921	405	20	potential	potential	NOUN
gs-3921	405	21	to	to	PART
gs-3921	405	22	significantly	significantly	ADV
gs-3921	405	23	reduce	reduce	VERB
gs-3921	405	24	the	the	DET
gs-3921	405	25	incidence	incidence	NOUN
gs-3921	405	26	and	and	CCONJ
gs-3921	405	27	severity	severity	NOUN
gs-3921	405	28	of	of	ADP
gs-3921	405	29	medication	medication	NOUN
gs-3921	405	30	-	-	PUNCT
gs-3921	405	31	induced	induce	VERB
gs-3921	405	32	adverse	adverse	ADJ
gs-3921	405	33	effects	effect	NOUN
gs-3921	405	34	.	.	PUNCT
gs-3921	406	1	this	this	DET
gs-3921	406	2	comprehensive	comprehensive	ADJ
gs-3921	406	3	analysis	analysis	NOUN
gs-3921	406	4	elucidates	elucidate	VERB
gs-3921	406	5	the	the	DET
gs-3921	406	6	multifactorial	multifactorial	ADJ
gs-3921	406	7	nature	nature	NOUN
gs-3921	406	8	of	of	ADP
gs-3921	406	9	medication	medication	NOUN
gs-3921	406	10	safety	safety	NOUN
gs-3921	406	11	,	,	PUNCT
gs-3921	406	12	underscoring	underscore	VERB
gs-3921	406	13	the	the	DET
gs-3921	406	14	interplay	interplay	NOUN
gs-3921	406	15	between	between	ADP
gs-3921	406	16	genetic	genetic	ADJ
gs-3921	406	17	variability	variability	NOUN
gs-3921	406	18	,	,	PUNCT
gs-3921	406	19	patient	patient	NOUN
gs-3921	406	20	-	-	PUNCT
gs-3921	406	21	centered	center	VERB
gs-3921	406	22	approaches	approach	NOUN
gs-3921	406	23	,	,	PUNCT
gs-3921	406	24	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	406	25	,	,	PUNCT
gs-3921	406	26	and	and	CCONJ
gs-3921	406	27	evolving	evolve	VERB
gs-3921	406	28	therapeutic	therapeutic	ADJ
gs-3921	406	29	strategies	strategy	NOUN
gs-3921	406	30	.	.	PUNCT
gs-3921	407	1	the	the	DET
gs-3921	407	2	findings	finding	NOUN
gs-3921	407	3	corroborate	corroborate	VERB
gs-3921	407	4	the	the	DET
gs-3921	407	5	critical	critical	ADJ
gs-3921	407	6	importance	importance	NOUN
gs-3921	407	7	of	of	ADP
gs-3921	407	8	incorporating	incorporate	VERB
gs-3921	407	9	genetic	genetic	ADJ
gs-3921	407	10	information	information	NOUN
gs-3921	407	11	alongside	alongside	ADP
gs-3921	407	12	clinical	clinical	ADJ
gs-3921	407	13	,	,	PUNCT
gs-3921	407	14	demographic	demographic	ADJ
gs-3921	407	15	,	,	PUNCT
gs-3921	407	16	and	and	CCONJ
gs-3921	407	17	environmental	environmental	ADJ
gs-3921	407	18	factors	factor	NOUN
gs-3921	407	19	to	to	PART
gs-3921	407	20	optimize	optimize	VERB
gs-3921	407	21	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	407	22	and	and	CCONJ
gs-3921	407	23	enhance	enhance	VERB
gs-3921	407	24	patient	patient	ADJ
gs-3921	407	25	outcomes	outcome	NOUN
gs-3921	407	26	.	.	PUNCT
gs-3921	408	1	implications	implication	NOUN
gs-3921	408	2	of	of	ADP
gs-3921	408	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	408	4	variability	variability	NOUN
gs-3921	408	5	on	on	ADP
gs-3921	408	6	clinical	clinical	ADJ
gs-3921	408	7	outcomes	outcome	NOUN
gs-3921	408	8	genetic	genetic	ADJ
gs-3921	408	9	polymorphisms	polymorphism	NOUN
gs-3921	408	10	that	that	PRON
gs-3921	408	11	alter	alter	VERB
gs-3921	408	12	drug	drug	NOUN
gs-3921	408	13	metabolism	metabolism	NOUN
gs-3921	408	14	and	and	CCONJ
gs-3921	408	15	response	response	NOUN
gs-3921	408	16	are	be	AUX
gs-3921	408	17	welldocumented	welldocumente	VERB
gs-3921	408	18	determinants	determinant	NOUN
gs-3921	408	19	of	of	ADP
gs-3921	408	20	interindividual	interindividual	ADJ
gs-3921	408	21	variability	variability	NOUN
gs-3921	408	22	in	in	ADP
gs-3921	408	23	therapeutic	therapeutic	ADJ
gs-3921	408	24	efficacy	efficacy	NOUN
gs-3921	408	25	and	and	CCONJ
gs-3921	408	26	toxicity	toxicity	NOUN
gs-3921	408	27	.	.	PUNCT
gs-3921	409	1	the	the	DET
gs-3921	409	2	identification	identification	NOUN
gs-3921	409	3	of	of	ADP
gs-3921	409	4	actionable	actionable	ADJ
gs-3921	409	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	409	6	markers	marker	NOUN
gs-3921	409	7	has	have	AUX
gs-3921	409	8	been	be	AUX
gs-3921	409	9	instrumental	instrumental	ADJ
gs-3921	409	10	in	in	ADP
gs-3921	409	11	guiding	guide	VERB
gs-3921	409	12	clinical	clinical	ADJ
gs-3921	409	13	decisions	decision	NOUN
gs-3921	409	14	for	for	ADP
gs-3921	409	15	drugs	drug	NOUN
gs-3921	409	16	with	with	ADP
gs-3921	409	17	narrow	narrow	ADJ
gs-3921	409	18	therapeutic	therapeutic	ADJ
gs-3921	409	19	indices	index	NOUN
gs-3921	409	20	or	or	CCONJ
gs-3921	409	21	severe	severe	ADJ
gs-3921	409	22	adverse	adverse	ADJ
gs-3921	409	23	event	event	NOUN
gs-3921	409	24	profiles	profile	NOUN
gs-3921	409	25	.	.	PUNCT
gs-3921	410	1	clinical	clinical	ADJ
gs-3921	410	2	guidelines	guideline	NOUN
gs-3921	410	3	,	,	PUNCT
gs-3921	410	4	such	such	ADJ
gs-3921	410	5	as	as	ADP
gs-3921	410	6	those	those	PRON
gs-3921	410	7	promulgated	promulgate	VERB
gs-3921	410	8	by	by	ADP
gs-3921	410	9	cpic	cpic	NOUN
gs-3921	410	10	and	and	CCONJ
gs-3921	410	11	the	the	DET
gs-3921	410	12	dutch	dutch	ADJ
gs-3921	410	13	pharmacogenetics	pharmacogenetics	PROPN
gs-3921	410	14	working	working	PROPN
gs-3921	410	15	group	group	NOUN
gs-3921	410	16	,	,	PUNCT
gs-3921	410	17	offer	offer	VERB
gs-3921	410	18	evidence	evidence	NOUN
gs-3921	410	19	-	-	PUNCT
gs-3921	410	20	based	base	VERB
gs-3921	410	21	frameworks	framework	NOUN
gs-3921	410	22	that	that	PRON
gs-3921	410	23	,	,	PUNCT
gs-3921	410	24	if	if	SCONJ
gs-3921	410	25	widely	widely	ADV
gs-3921	410	26	adopted	adopt	VERB
gs-3921	410	27	,	,	PUNCT
gs-3921	410	28	could	could	AUX
gs-3921	410	29	markedly	markedly	ADV
gs-3921	410	30	improve	improve	VERB
gs-3921	410	31	prescribing	prescribing	NOUN
gs-3921	410	32	accuracy	accuracy	NOUN
gs-3921	410	33	and	and	CCONJ
gs-3921	410	34	patient	patient	ADJ
gs-3921	410	35	safety	safety	NOUN
gs-3921	410	36	.	.	PUNCT
gs-3921	411	1	however	however	ADV
gs-3921	411	2	,	,	PUNCT
gs-3921	411	3	the	the	DET
gs-3921	411	4	clinical	clinical	ADJ
gs-3921	411	5	utility	utility	NOUN
gs-3921	411	6	of	of	ADP
gs-3921	411	7	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	411	8	extends	extend	VERB
gs-3921	411	9	beyond	beyond	ADP
gs-3921	411	10	isolated	isolated	ADJ
gs-3921	411	11	genedrug	genedrug	NOUN
gs-3921	411	12	pairs	pair	NOUN
gs-3921	411	13	.	.	PUNCT
gs-3921	412	1	the	the	DET
gs-3921	412	2	dynamic	dynamic	ADJ
gs-3921	412	3	complexity	complexity	NOUN
gs-3921	412	4	of	of	ADP
gs-3921	412	5	drug	drug	NOUN
gs-3921	412	6	response	response	NOUN
gs-3921	412	7	,	,	PUNCT
gs-3921	412	8	influenced	influence	VERB
gs-3921	412	9	by	by	ADP
gs-3921	412	10	polygenic	polygenic	ADJ
gs-3921	412	11	interactions	interaction	NOUN
gs-3921	412	12	and	and	CCONJ
gs-3921	412	13	epigenetic	epigenetic	ADJ
gs-3921	412	14	modifications	modification	NOUN
gs-3921	412	15	,	,	PUNCT
gs-3921	412	16	necessitates	necessitate	VERB
gs-3921	412	17	more	more	ADJ
gs-3921	412	18	comprehensive	comprehensive	ADJ
gs-3921	412	19	models	model	NOUN
gs-3921	412	20	that	that	PRON
gs-3921	412	21	integrate	integrate	VERB
gs-3921	412	22	multi	multi	ADJ
gs-3921	412	23	-	-	ADJ
gs-3921	412	24	omic	omic	ADJ
gs-3921	412	25	data	datum	NOUN
gs-3921	412	26	and	and	CCONJ
gs-3921	412	27	environmental	environmental	ADJ
gs-3921	412	28	inputs	input	NOUN
gs-3921	412	29	.	.	PUNCT
gs-3921	413	1	emerging	emerge	VERB
gs-3921	413	2	evidence	evidence	NOUN
gs-3921	413	3	supports	support	VERB
gs-3921	413	4	the	the	DET
gs-3921	413	5	notion	notion	NOUN
gs-3921	413	6	that	that	SCONJ
gs-3921	413	7	simplistic	simplistic	ADJ
gs-3921	413	8	single	single	ADJ
gs-3921	413	9	-	-	PUNCT
gs-3921	413	10	gene	gene	NOUN
gs-3921	413	11	testing	testing	NOUN
gs-3921	413	12	may	may	AUX
gs-3921	413	13	insufficiently	insufficiently	ADV
gs-3921	413	14	capture	capture	VERB
gs-3921	413	15	the	the	DET
gs-3921	413	16	nuanced	nuanced	ADJ
gs-3921	413	17	determinants	determinant	NOUN
gs-3921	413	18	of	of	ADP
gs-3921	413	19	adrs	adr	NOUN
gs-3921	413	20	and	and	CCONJ
gs-3921	413	21	therapeutic	therapeutic	ADJ
gs-3921	413	22	response	response	NOUN
gs-3921	413	23	.	.	PUNCT
gs-3921	414	1	future	future	ADJ
gs-3921	414	2	research	research	NOUN
gs-3921	414	3	must	must	AUX
gs-3921	414	4	prioritize	prioritize	VERB
gs-3921	414	5	the	the	DET
gs-3921	414	6	development	development	NOUN
gs-3921	414	7	of	of	ADP
gs-3921	414	8	integrative	integrative	ADJ
gs-3921	414	9	predictive	predictive	ADJ
gs-3921	414	10	algorithms	algorithm	NOUN
gs-3921	414	11	and	and	CCONJ
gs-3921	414	12	validation	validation	NOUN
gs-3921	414	13	in	in	ADP
gs-3921	414	14	diverse	diverse	ADJ
gs-3921	414	15	clinical	clinical	ADJ
gs-3921	414	16	contexts	contexts	NOUN
gs-3921	414	17	.	.	PUNCT
gs-3921	415	1	challenges	challenge	NOUN
gs-3921	415	2	to	to	ADP
gs-3921	415	3	clinical	clinical	ADJ
gs-3921	415	4	implementation	implementation	NOUN
gs-3921	415	5	despite	despite	SCONJ
gs-3921	415	6	clear	clear	ADJ
gs-3921	415	7	scientific	scientific	ADJ
gs-3921	415	8	validation	validation	NOUN
gs-3921	415	9	,	,	PUNCT
gs-3921	415	10	the	the	DET
gs-3921	415	11	translation	translation	NOUN
gs-3921	415	12	of	of	ADP
gs-3921	415	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	415	14	knowledge	knowledge	NOUN
gs-3921	415	15	into	into	ADP
gs-3921	415	16	standard	standard	ADJ
gs-3921	415	17	clinical	clinical	ADJ
gs-3921	415	18	practice	practice	NOUN
gs-3921	415	19	remains	remains	AUX
gs-3921	415	20	impeded	impede	VERB
gs-3921	415	21	by	by	ADP
gs-3921	415	22	systemic	systemic	ADJ
gs-3921	415	23	,	,	PUNCT
gs-3921	415	24	educational	educational	ADJ
gs-3921	415	25	,	,	PUNCT
gs-3921	415	26	economic	economic	ADJ
gs-3921	415	27	,	,	PUNCT
gs-3921	415	28	and	and	CCONJ
gs-3921	415	29	sociocultural	sociocultural	ADJ
gs-3921	415	30	barriers	barrier	NOUN
gs-3921	415	31	.	.	PUNCT
gs-3921	416	1	the	the	DET
gs-3921	416	2	insufficient	insufficient	ADJ
gs-3921	416	3	integration	integration	NOUN
gs-3921	416	4	of	of	ADP
gs-3921	416	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	416	6	data	datum	NOUN
gs-3921	416	7	into	into	ADP
gs-3921	416	8	electronic	electronic	ADJ
gs-3921	416	9	health	health	NOUN
gs-3921	416	10	records	record	NOUN
gs-3921	416	11	and	and	CCONJ
gs-3921	416	12	decision	decision	NOUN
gs-3921	416	13	support	support	NOUN
gs-3921	416	14	tools	tool	NOUN
gs-3921	416	15	limits	limit	VERB
gs-3921	416	16	accessibility	accessibility	NOUN
gs-3921	416	17	and	and	CCONJ
gs-3921	416	18	usability	usability	NOUN
gs-3921	416	19	at	at	ADP
gs-3921	416	20	the	the	DET
gs-3921	416	21	point	point	NOUN
gs-3921	416	22	of	of	ADP
gs-3921	416	23	care	care	NOUN
gs-3921	416	24	.	.	PUNCT
gs-3921	417	1	healthcare	healthcare	NOUN
gs-3921	417	2	provider	provider	NOUN
gs-3921	417	3	unfamiliarity	unfamiliarity	NOUN
gs-3921	417	4	and	and	CCONJ
gs-3921	417	5	lack	lack	NOUN
gs-3921	417	6	of	of	ADP
gs-3921	417	7	confidence	confidence	NOUN
gs-3921	417	8	in	in	ADP
gs-3921	417	9	interpreting	interpret	VERB
gs-3921	417	10	genetic	genetic	ADJ
gs-3921	417	11	data	datum	NOUN
gs-3921	417	12	further	far	ADV
gs-3921	417	13	hinder	hinder	VERB
gs-3921	417	14	adoption	adoption	NOUN
gs-3921	417	15	.	.	PUNCT
gs-3921	418	1	economic	economic	ADJ
gs-3921	418	2	considerations	consideration	NOUN
gs-3921	418	3	,	,	PUNCT
gs-3921	418	4	including	include	VERB
gs-3921	418	5	testing	testing	NOUN
gs-3921	418	6	costs	cost	NOUN
gs-3921	418	7	,	,	PUNCT
gs-3921	418	8	reimbursement	reimbursement	NOUN
gs-3921	418	9	policies	policy	NOUN
gs-3921	418	10	,	,	PUNCT
gs-3921	418	11	and	and	CCONJ
gs-3921	418	12	costeffectiveness	costeffectiveness	NOUN
gs-3921	418	13	evidence	evidence	NOUN
gs-3921	418	14	gaps	gap	NOUN
gs-3921	418	15	,	,	PUNCT
gs-3921	418	16	pose	pose	VERB
gs-3921	418	17	significant	significant	ADJ
gs-3921	418	18	obstacles	obstacle	NOUN
gs-3921	418	19	,	,	PUNCT
gs-3921	418	20	particularly	particularly	ADV
gs-3921	418	21	in	in	ADP
gs-3921	418	22	resource	resource	NOUN
gs-3921	418	23	-	-	PUNCT
gs-3921	418	24	limited	limit	VERB
gs-3921	418	25	georgian	georgian	ADJ
gs-3921	418	26	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	418	27	მეცნიერები	მეცნიერები	NOUN
gs-3921	418	28	ტ.	ტ.	VERB
gs-3921	418	29	7	7	NUM
gs-3921	418	30	n	n	DET
gs-3921	418	31	3	3	NUM
gs-3921	418	32	,	,	PUNCT
gs-3921	418	33	2025	2025	NUM
gs-3921	418	34	242	242	NUM
gs-3921	418	35	settings	setting	NOUN
gs-3921	418	36	.	.	PUNCT
gs-3921	419	1	health	health	NOUN
gs-3921	419	2	systems	system	NOUN
gs-3921	419	3	must	must	AUX
gs-3921	419	4	balance	balance	VERB
gs-3921	419	5	the	the	DET
gs-3921	419	6	upfront	upfront	ADJ
gs-3921	419	7	costs	cost	NOUN
gs-3921	419	8	of	of	ADP
gs-3921	419	9	genetic	genetic	ADJ
gs-3921	419	10	testing	testing	NOUN
gs-3921	419	11	infrastructure	infrastructure	NOUN
gs-3921	419	12	against	against	ADP
gs-3921	419	13	potential	potential	ADJ
gs-3921	419	14	long	long	ADJ
gs-3921	419	15	-	-	PUNCT
gs-3921	419	16	term	term	NOUN
gs-3921	419	17	savings	saving	NOUN
gs-3921	419	18	from	from	ADP
gs-3921	419	19	reduced	reduce	VERB
gs-3921	419	20	adr	adr	PROPN
gs-3921	419	21	-	-	PUNCT
gs-3921	419	22	related	relate	VERB
gs-3921	419	23	morbidity	morbidity	NOUN
gs-3921	419	24	and	and	CCONJ
gs-3921	419	25	hospitalizations	hospitalization	NOUN
gs-3921	419	26	.	.	PUNCT
gs-3921	420	1	policy	policy	NOUN
gs-3921	420	2	frameworks	framework	NOUN
gs-3921	420	3	that	that	PRON
gs-3921	420	4	incentivize	incentivize	VERB
gs-3921	420	5	adoption	adoption	NOUN
gs-3921	420	6	through	through	ADP
gs-3921	420	7	value	value	NOUN
gs-3921	420	8	-	-	PUNCT
gs-3921	420	9	based	base	VERB
gs-3921	420	10	reimbursement	reimbursement	NOUN
gs-3921	420	11	may	may	AUX
gs-3921	420	12	accelerate	accelerate	VERB
gs-3921	420	13	integration	integration	NOUN
gs-3921	420	14	.	.	PUNCT
gs-3921	421	1	patient	patient	ADJ
gs-3921	421	2	acceptance	acceptance	NOUN
gs-3921	421	3	and	and	CCONJ
gs-3921	421	4	engagement	engagement	NOUN
gs-3921	421	5	represent	represent	VERB
gs-3921	421	6	critical	critical	ADJ
gs-3921	421	7	determinants	determinant	NOUN
gs-3921	421	8	of	of	ADP
gs-3921	421	9	successful	successful	ADJ
gs-3921	421	10	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	421	11	implementation	implementation	NOUN
gs-3921	421	12	.	.	PUNCT
gs-3921	422	1	cultural	cultural	ADJ
gs-3921	422	2	beliefs	beliefs	PROPN
gs-3921	422	3	,	,	PUNCT
gs-3921	422	4	health	health	NOUN
gs-3921	422	5	literacy	literacy	NOUN
gs-3921	422	6	levels	level	NOUN
gs-3921	422	7	,	,	PUNCT
gs-3921	422	8	and	and	CCONJ
gs-3921	422	9	concerns	concern	NOUN
gs-3921	422	10	regarding	regard	VERB
gs-3921	422	11	privacy	privacy	NOUN
gs-3921	422	12	and	and	CCONJ
gs-3921	422	13	discrimination	discrimination	NOUN
gs-3921	422	14	influence	influence	NOUN
gs-3921	422	15	willingness	willingness	NOUN
gs-3921	422	16	to	to	PART
gs-3921	422	17	undergo	undergo	VERB
gs-3921	422	18	testing	testing	NOUN
gs-3921	422	19	.	.	PUNCT
gs-3921	423	1	effective	effective	ADJ
gs-3921	423	2	patient	patient	NOUN
gs-3921	423	3	-	-	PUNCT
gs-3921	423	4	centered	center	VERB
gs-3921	423	5	communication	communication	NOUN
gs-3921	423	6	strategies	strategy	NOUN
gs-3921	423	7	and	and	CCONJ
gs-3921	423	8	equitable	equitable	ADJ
gs-3921	423	9	access	access	NOUN
gs-3921	423	10	to	to	ADP
gs-3921	423	11	genetic	genetic	ADJ
gs-3921	423	12	counseling	counseling	NOUN
gs-3921	423	13	services	service	NOUN
gs-3921	423	14	are	be	AUX
gs-3921	423	15	paramount	paramount	ADJ
gs-3921	423	16	to	to	ADP
gs-3921	423	17	fostering	foster	VERB
gs-3921	423	18	informed	informed	ADJ
gs-3921	423	19	decision	decision	NOUN
gs-3921	423	20	-	-	PUNCT
gs-3921	423	21	making	making	NOUN
gs-3921	423	22	and	and	CCONJ
gs-3921	423	23	trust	trust	NOUN
gs-3921	423	24	.	.	PUNCT
gs-3921	424	1	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	424	2	and	and	CCONJ
gs-3921	424	3	real	real	ADJ
gs-3921	424	4	-	-	PUNCT
gs-3921	424	5	world	world	NOUN
gs-3921	424	6	evidence	evidence	NOUN
gs-3921	424	7	integration	integration	NOUN
gs-3921	424	8	the	the	DET
gs-3921	424	9	advent	advent	NOUN
gs-3921	424	10	of	of	ADP
gs-3921	424	11	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	424	12	enriches	enrich	VERB
gs-3921	424	13	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	424	14	methodologies	methodology	NOUN
gs-3921	424	15	by	by	ADP
gs-3921	424	16	enabling	enable	VERB
gs-3921	424	17	stratified	stratified	ADJ
gs-3921	424	18	risk	risk	NOUN
gs-3921	424	19	assessment	assessment	NOUN
gs-3921	424	20	and	and	CCONJ
gs-3921	424	21	refined	refined	ADJ
gs-3921	424	22	signal	signal	NOUN
gs-3921	424	23	detection	detection	NOUN
gs-3921	424	24	.	.	PUNCT
gs-3921	425	1	real	real	ADJ
gs-3921	425	2	-	-	PUNCT
gs-3921	425	3	world	world	NOUN
gs-3921	425	4	data	datum	NOUN
gs-3921	425	5	analytics	analytic	NOUN
gs-3921	425	6	,	,	PUNCT
gs-3921	425	7	incorporating	incorporate	VERB
gs-3921	425	8	genetic	genetic	ADJ
gs-3921	425	9	profiles	profile	NOUN
gs-3921	425	10	,	,	PUNCT
gs-3921	425	11	augment	augment	VERB
gs-3921	425	12	traditional	traditional	ADJ
gs-3921	425	13	surveillance	surveillance	NOUN
gs-3921	425	14	systems	system	NOUN
gs-3921	425	15	and	and	CCONJ
gs-3921	425	16	facilitate	facilitate	VERB
gs-3921	425	17	earlier	early	ADJ
gs-3921	425	18	identification	identification	NOUN
gs-3921	425	19	of	of	ADP
gs-3921	425	20	adrs	adr	NOUN
gs-3921	425	21	in	in	ADP
gs-3921	425	22	genetically	genetically	ADV
gs-3921	425	23	susceptible	susceptible	ADJ
gs-3921	425	24	subpopulations	subpopulation	NOUN
gs-3921	425	25	.	.	PUNCT
gs-3921	426	1	the	the	DET
gs-3921	426	2	incorporation	incorporation	NOUN
gs-3921	426	3	of	of	ADP
gs-3921	426	4	digital	digital	ADJ
gs-3921	426	5	health	health	NOUN
gs-3921	426	6	technologies	technology	NOUN
gs-3921	426	7	and	and	CCONJ
gs-3921	426	8	patient	patient	NOUN
gs-3921	426	9	-	-	PUNCT
gs-3921	426	10	reported	report	VERB
gs-3921	426	11	outcomes	outcome	NOUN
gs-3921	426	12	further	far	ADV
gs-3921	426	13	enhances	enhance	VERB
gs-3921	426	14	the	the	DET
gs-3921	426	15	timeliness	timeliness	NOUN
gs-3921	426	16	and	and	CCONJ
gs-3921	426	17	granularity	granularity	NOUN
gs-3921	426	18	of	of	ADP
gs-3921	426	19	safety	safety	NOUN
gs-3921	426	20	data	datum	NOUN
gs-3921	426	21	.	.	PUNCT
gs-3921	427	1	nevertheless	nevertheless	ADV
gs-3921	427	2	,	,	PUNCT
gs-3921	427	3	standardizing	standardize	VERB
gs-3921	427	4	the	the	DET
gs-3921	427	5	capture	capture	NOUN
gs-3921	427	6	and	and	CCONJ
gs-3921	427	7	integration	integration	NOUN
gs-3921	427	8	of	of	ADP
gs-3921	427	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	427	10	information	information	NOUN
gs-3921	427	11	within	within	ADP
gs-3921	427	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	427	13	frameworks	framework	NOUN
gs-3921	427	14	remains	remain	VERB
gs-3921	427	15	a	a	DET
gs-3921	427	16	challenge	challenge	NOUN
gs-3921	427	17	.	.	PUNCT
gs-3921	428	1	data	datum	NOUN
gs-3921	428	2	interoperability	interoperability	NOUN
gs-3921	428	3	,	,	PUNCT
gs-3921	428	4	quality	quality	NOUN
gs-3921	428	5	assurance	assurance	NOUN
gs-3921	428	6	,	,	PUNCT
gs-3921	428	7	and	and	CCONJ
gs-3921	428	8	privacy	privacy	NOUN
gs-3921	428	9	protections	protection	NOUN
gs-3921	428	10	are	be	AUX
gs-3921	428	11	essential	essential	ADJ
gs-3921	428	12	to	to	PART
gs-3921	428	13	maximize	maximize	VERB
gs-3921	428	14	the	the	DET
gs-3921	428	15	utility	utility	NOUN
gs-3921	428	16	of	of	ADP
gs-3921	428	17	integrated	integrate	VERB
gs-3921	428	18	systems	system	NOUN
gs-3921	428	19	.	.	PUNCT
gs-3921	429	1	cross	cross	ADJ
gs-3921	429	2	-	-	ADJ
gs-3921	429	3	sector	sector	ADJ
gs-3921	429	4	collaboration	collaboration	NOUN
gs-3921	429	5	among	among	ADP
gs-3921	429	6	regulatory	regulatory	ADJ
gs-3921	429	7	agencies	agency	NOUN
gs-3921	429	8	,	,	PUNCT
gs-3921	429	9	healthcare	healthcare	NOUN
gs-3921	429	10	providers	provider	NOUN
gs-3921	429	11	,	,	PUNCT
gs-3921	429	12	researchers	researcher	NOUN
gs-3921	429	13	,	,	PUNCT
gs-3921	429	14	and	and	CCONJ
gs-3921	429	15	patients	patient	NOUN
gs-3921	429	16	is	be	AUX
gs-3921	429	17	critical	critical	ADJ
gs-3921	429	18	to	to	ADP
gs-3921	429	19	developing	develop	VERB
gs-3921	429	20	robust	robust	ADJ
gs-3921	429	21	,	,	PUNCT
gs-3921	429	22	scalable	scalable	ADJ
gs-3921	429	23	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	429	24	infrastructures	infrastructure	NOUN
gs-3921	429	25	.	.	PUNCT
gs-3921	430	1	the	the	DET
gs-3921	430	2	complexities	complexity	NOUN
gs-3921	430	3	of	of	ADP
gs-3921	430	4	polypharmacy	polypharmacy	NOUN
gs-3921	430	5	and	and	CCONJ
gs-3921	430	6	personalized	personalized	ADJ
gs-3921	430	7	therapeutics	therapeutic	NOUN
gs-3921	430	8	the	the	DET
gs-3921	430	9	increasing	increase	VERB
gs-3921	430	10	prevalence	prevalence	NOUN
gs-3921	430	11	of	of	ADP
gs-3921	430	12	polypharmacy	polypharmacy	NOUN
gs-3921	430	13	,	,	PUNCT
gs-3921	430	14	particularly	particularly	ADV
gs-3921	430	15	among	among	ADP
gs-3921	430	16	aging	age	VERB
gs-3921	430	17	populations	population	NOUN
gs-3921	430	18	,	,	PUNCT
gs-3921	430	19	compounds	compound	VERB
gs-3921	430	20	the	the	DET
gs-3921	430	21	risk	risk	NOUN
gs-3921	430	22	of	of	ADP
gs-3921	430	23	medication	medication	NOUN
gs-3921	430	24	-	-	PUNCT
gs-3921	430	25	related	relate	VERB
gs-3921	430	26	adverse	adverse	ADJ
gs-3921	430	27	events	event	NOUN
gs-3921	430	28	.	.	PUNCT
gs-3921	431	1	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	431	2	offers	offer	VERB
gs-3921	431	3	valuable	valuable	ADJ
gs-3921	431	4	insights	insight	NOUN
gs-3921	431	5	into	into	ADP
gs-3921	431	6	individualized	individualized	ADJ
gs-3921	431	7	drug	drug	NOUN
gs-3921	431	8	metabolism	metabolism	NOUN
gs-3921	431	9	capacity	capacity	NOUN
gs-3921	431	10	,	,	PUNCT
gs-3921	431	11	thereby	thereby	ADV
gs-3921	431	12	informing	inform	VERB
gs-3921	431	13	safer	safe	ADJ
gs-3921	431	14	polypharmacy	polypharmacy	NOUN
gs-3921	431	15	management	management	NOUN
gs-3921	431	16	.	.	PUNCT
gs-3921	432	1	however	however	ADV
gs-3921	432	2	,	,	PUNCT
gs-3921	432	3	the	the	DET
gs-3921	432	4	clinical	clinical	ADJ
gs-3921	432	5	complexity	complexity	NOUN
gs-3921	432	6	introduced	introduce	VERB
gs-3921	432	7	by	by	ADP
gs-3921	432	8	multiple	multiple	ADJ
gs-3921	432	9	interacting	interact	VERB
gs-3921	432	10	drugs	drug	NOUN
gs-3921	432	11	requires	require	VERB
gs-3921	432	12	sophisticated	sophisticated	ADJ
gs-3921	432	13	decision	decision	NOUN
gs-3921	432	14	support	support	NOUN
gs-3921	432	15	systems	system	NOUN
gs-3921	432	16	that	that	PRON
gs-3921	432	17	synthesize	synthesize	VERB
gs-3921	432	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	432	19	,	,	PUNCT
gs-3921	432	20	clinical	clinical	ADJ
gs-3921	432	21	,	,	PUNCT
gs-3921	432	22	and	and	CCONJ
gs-3921	432	23	pharmacological	pharmacological	ADJ
gs-3921	432	24	data	datum	NOUN
gs-3921	432	25	.	.	PUNCT
gs-3921	433	1	interprofessional	interprofessional	ADJ
gs-3921	433	2	collaboration	collaboration	NOUN
gs-3921	433	3	,	,	PUNCT
gs-3921	433	4	especially	especially	ADV
gs-3921	433	5	involving	involve	VERB
gs-3921	433	6	clinical	clinical	ADJ
gs-3921	433	7	pharmacists	pharmacist	NOUN
gs-3921	433	8	,	,	PUNCT
gs-3921	433	9	is	be	AUX
gs-3921	433	10	essential	essential	ADJ
gs-3921	433	11	for	for	ADP
gs-3921	433	12	optimizing	optimize	VERB
gs-3921	433	13	medication	medication	NOUN
gs-3921	433	14	regimens	regimen	NOUN
gs-3921	433	15	in	in	ADP
gs-3921	433	16	this	this	DET
gs-3921	433	17	context	context	NOUN
gs-3921	433	18	.	.	PUNCT
gs-3921	434	1	education	education	NOUN
gs-3921	434	2	and	and	CCONJ
gs-3921	434	3	training	training	NOUN
gs-3921	434	4	programs	program	NOUN
gs-3921	434	5	should	should	AUX
gs-3921	434	6	emphasize	emphasize	VERB
gs-3921	434	7	the	the	DET
gs-3921	434	8	integration	integration	NOUN
gs-3921	434	9	of	of	ADP
gs-3921	434	10	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	434	11	into	into	ADP
gs-3921	434	12	medication	medication	NOUN
gs-3921	434	13	therapy	therapy	NOUN
gs-3921	434	14	management	management	NOUN
gs-3921	434	15	to	to	PART
gs-3921	434	16	address	address	VERB
gs-3921	434	17	the	the	DET
gs-3921	434	18	nuanced	nuanced	ADJ
gs-3921	434	19	challenges	challenge	NOUN
gs-3921	434	20	posed	pose	VERB
gs-3921	434	21	by	by	ADP
gs-3921	434	22	polypharmacy	polypharmacy	NOUN
gs-3921	434	23	.	.	PUNCT
gs-3921	435	1	technological	technological	ADJ
gs-3921	435	2	innovations	innovation	NOUN
gs-3921	435	3	and	and	CCONJ
gs-3921	435	4	future	future	ADJ
gs-3921	435	5	directions	direction	NOUN
gs-3921	435	6	emerging	emerge	VERB
gs-3921	435	7	digital	digital	ADJ
gs-3921	435	8	health	health	NOUN
gs-3921	435	9	technologies	technology	NOUN
gs-3921	435	10	and	and	CCONJ
gs-3921	435	11	artificial	artificial	ADJ
gs-3921	435	12	intelligence	intelligence	NOUN
gs-3921	435	13	are	be	AUX
gs-3921	435	14	poised	poise	VERB
gs-3921	435	15	to	to	PART
gs-3921	435	16	accelerate	accelerate	VERB
gs-3921	435	17	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	435	18	integration	integration	NOUN
gs-3921	435	19	by	by	ADP
gs-3921	435	20	enhancing	enhance	VERB
gs-3921	435	21	data	datum	NOUN
gs-3921	435	22	analysis	analysis	NOUN
gs-3921	435	23	,	,	PUNCT
gs-3921	435	24	patient	patient	ADJ
gs-3921	435	25	monitoring	monitoring	NOUN
gs-3921	435	26	,	,	PUNCT
gs-3921	435	27	and	and	CCONJ
gs-3921	435	28	clinical	clinical	ADJ
gs-3921	435	29	decision	decision	NOUN
gs-3921	435	30	support	support	NOUN
gs-3921	435	31	.	.	PUNCT
gs-3921	436	1	these	these	DET
gs-3921	436	2	tools	tool	NOUN
gs-3921	436	3	promise	promise	VERB
gs-3921	436	4	to	to	PART
gs-3921	436	5	bridge	bridge	VERB
gs-3921	436	6	existing	exist	VERB
gs-3921	436	7	gaps	gap	NOUN
gs-3921	436	8	in	in	ADP
gs-3921	436	9	knowledge	knowledge	NOUN
gs-3921	436	10	translation	translation	NOUN
gs-3921	436	11	and	and	CCONJ
gs-3921	436	12	georgian	georgian	ADJ
gs-3921	436	13	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	436	14	მეცნიერები	მეცნიერები	NOUN
gs-3921	436	15	ტ.	ტ.	VERB
gs-3921	436	16	7	7	NUM
gs-3921	436	17	n	n	DET
gs-3921	436	18	3	3	NUM
gs-3921	436	19	,	,	PUNCT
gs-3921	436	20	2025	2025	NUM
gs-3921	436	21	243	243	NUM
gs-3921	436	22	operational	operational	ADJ
gs-3921	436	23	workflows	workflow	NOUN
gs-3921	436	24	.	.	PUNCT
gs-3921	437	1	however	however	ADV
gs-3921	437	2	,	,	PUNCT
gs-3921	437	3	their	their	PRON
gs-3921	437	4	implementation	implementation	NOUN
gs-3921	437	5	must	must	AUX
gs-3921	437	6	be	be	AUX
gs-3921	437	7	accompanied	accompany	VERB
gs-3921	437	8	by	by	ADP
gs-3921	437	9	rigorous	rigorous	ADJ
gs-3921	437	10	validation	validation	NOUN
gs-3921	437	11	,	,	PUNCT
gs-3921	437	12	user	user	NOUN
gs-3921	437	13	-	-	PUNCT
gs-3921	437	14	centered	center	VERB
gs-3921	437	15	design	design	NOUN
gs-3921	437	16	,	,	PUNCT
gs-3921	437	17	and	and	CCONJ
gs-3921	437	18	attention	attention	NOUN
gs-3921	437	19	to	to	ADP
gs-3921	437	20	ethical	ethical	ADJ
gs-3921	437	21	and	and	CCONJ
gs-3921	437	22	equity	equity	NOUN
gs-3921	437	23	considerations	consideration	NOUN
gs-3921	437	24	.	.	PUNCT
gs-3921	438	1	global	global	ADJ
gs-3921	438	2	collaboration	collaboration	NOUN
gs-3921	438	3	and	and	CCONJ
gs-3921	438	4	harmonization	harmonization	NOUN
gs-3921	438	5	of	of	ADP
gs-3921	438	6	regulatory	regulatory	ADJ
gs-3921	438	7	standards	standard	NOUN
gs-3921	438	8	will	will	AUX
gs-3921	438	9	facilitate	facilitate	VERB
gs-3921	438	10	the	the	DET
gs-3921	438	11	widespread	widespread	ADJ
gs-3921	438	12	adoption	adoption	NOUN
gs-3921	438	13	of	of	ADP
gs-3921	438	14	pharmacogenetic	pharmacogenetic	ADV
gs-3921	438	15	-	-	PUNCT
gs-3921	438	16	informed	inform	VERB
gs-3921	438	17	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	438	18	.	.	PUNCT
gs-3921	439	1	investments	investment	NOUN
gs-3921	439	2	in	in	ADP
gs-3921	439	3	capacity	capacity	NOUN
gs-3921	439	4	building	building	NOUN
gs-3921	439	5	,	,	PUNCT
gs-3921	439	6	infrastructure	infrastructure	NOUN
gs-3921	439	7	,	,	PUNCT
gs-3921	439	8	and	and	CCONJ
gs-3921	439	9	education	education	NOUN
gs-3921	439	10	are	be	AUX
gs-3921	439	11	necessary	necessary	ADJ
gs-3921	439	12	to	to	PART
gs-3921	439	13	realize	realize	VERB
gs-3921	439	14	the	the	DET
gs-3921	439	15	full	full	ADJ
gs-3921	439	16	potential	potential	NOUN
gs-3921	439	17	of	of	ADP
gs-3921	439	18	these	these	DET
gs-3921	439	19	advances	advance	NOUN
gs-3921	439	20	across	across	ADP
gs-3921	439	21	diverse	diverse	ADJ
gs-3921	439	22	healthcare	healthcare	NOUN
gs-3921	439	23	settings	setting	NOUN
gs-3921	439	24	.	.	PUNCT
gs-3921	440	1	the	the	DET
gs-3921	440	2	comprehensive	comprehensive	ADJ
gs-3921	440	3	exploration	exploration	NOUN
gs-3921	440	4	of	of	ADP
gs-3921	440	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	440	6	and	and	CCONJ
gs-3921	440	7	patient	patient	NOUN
gs-3921	440	8	-	-	PUNCT
gs-3921	440	9	centered	center	VERB
gs-3921	440	10	care	care	NOUN
gs-3921	440	11	approaches	approach	NOUN
gs-3921	440	12	reveals	reveal	VERB
gs-3921	440	13	both	both	DET
gs-3921	440	14	transformative	transformative	ADJ
gs-3921	440	15	opportunities	opportunity	NOUN
gs-3921	440	16	and	and	CCONJ
gs-3921	440	17	significant	significant	ADJ
gs-3921	440	18	implementation	implementation	NOUN
gs-3921	440	19	challenges	challenge	NOUN
gs-3921	440	20	in	in	ADP
gs-3921	440	21	the	the	DET
gs-3921	440	22	realm	realm	NOUN
gs-3921	440	23	of	of	ADP
gs-3921	440	24	medication	medication	NOUN
gs-3921	440	25	-	-	PUNCT
gs-3921	440	26	induced	induce	VERB
gs-3921	440	27	adverse	adverse	ADJ
gs-3921	440	28	effects	effect	NOUN
gs-3921	440	29	and	and	CCONJ
gs-3921	440	30	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	440	31	.	.	PUNCT
gs-3921	441	1	the	the	DET
gs-3921	441	2	path	path	NOUN
gs-3921	441	3	forward	forward	ADV
gs-3921	441	4	necessitates	necessitate	VERB
gs-3921	441	5	coordinated	coordinated	ADJ
gs-3921	441	6	multidisciplinary	multidisciplinary	ADJ
gs-3921	441	7	efforts	effort	NOUN
gs-3921	441	8	encompassing	encompass	VERB
gs-3921	441	9	scientific	scientific	ADJ
gs-3921	441	10	innovation	innovation	NOUN
gs-3921	441	11	,	,	PUNCT
gs-3921	441	12	healthcare	healthcare	NOUN
gs-3921	441	13	system	system	NOUN
gs-3921	441	14	redesign	redesign	NOUN
gs-3921	441	15	,	,	PUNCT
gs-3921	441	16	policy	policy	NOUN
gs-3921	441	17	development	development	NOUN
gs-3921	441	18	,	,	PUNCT
gs-3921	441	19	and	and	CCONJ
gs-3921	441	20	ethical	ethical	ADJ
gs-3921	441	21	stewardship	stewardship	NOUN
gs-3921	441	22	.	.	PUNCT
gs-3921	442	1	embracing	embrace	VERB
gs-3921	442	2	this	this	DET
gs-3921	442	3	integrated	integrate	VERB
gs-3921	442	4	framework	framework	NOUN
gs-3921	442	5	holds	hold	VERB
gs-3921	442	6	promise	promise	NOUN
gs-3921	442	7	for	for	ADP
gs-3921	442	8	achieving	achieve	VERB
gs-3921	442	9	safer	safe	ADJ
gs-3921	442	10	,	,	PUNCT
gs-3921	442	11	more	more	ADV
gs-3921	442	12	effective	effective	ADJ
gs-3921	442	13	,	,	PUNCT
gs-3921	442	14	and	and	CCONJ
gs-3921	442	15	personalized	personalize	VERB
gs-3921	442	16	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	442	17	that	that	PRON
gs-3921	442	18	improves	improve	VERB
gs-3921	442	19	patient	patient	ADJ
gs-3921	442	20	outcomes	outcome	NOUN
gs-3921	442	21	globally	globally	ADV
gs-3921	442	22	.	.	PUNCT
gs-3921	443	1	the	the	DET
gs-3921	443	2	evolution	evolution	NOUN
gs-3921	443	3	of	of	ADP
gs-3921	443	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	443	5	from	from	ADP
gs-3921	443	6	a	a	DET
gs-3921	443	7	theoretical	theoretical	ADJ
gs-3921	443	8	framework	framework	NOUN
gs-3921	443	9	to	to	ADP
gs-3921	443	10	a	a	DET
gs-3921	443	11	practical	practical	ADJ
gs-3921	443	12	tool	tool	NOUN
gs-3921	443	13	in	in	ADP
gs-3921	443	14	clinical	clinical	ADJ
gs-3921	443	15	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	443	16	marks	mark	VERB
gs-3921	443	17	a	a	DET
gs-3921	443	18	significant	significant	ADJ
gs-3921	443	19	advancement	advancement	NOUN
gs-3921	443	20	in	in	ADP
gs-3921	443	21	personalized	personalized	ADJ
gs-3921	443	22	medicine	medicine	NOUN
gs-3921	443	23	.	.	PUNCT
gs-3921	444	1	the	the	DET
gs-3921	444	2	extensive	extensive	ADJ
gs-3921	444	3	evidence	evidence	NOUN
gs-3921	444	4	reviewed	review	VERB
gs-3921	444	5	highlights	highlight	NOUN
gs-3921	444	6	the	the	DET
gs-3921	444	7	intricate	intricate	ADJ
gs-3921	444	8	interplay	interplay	NOUN
gs-3921	444	9	between	between	ADP
gs-3921	444	10	genetic	genetic	ADJ
gs-3921	444	11	polymorphisms	polymorphism	NOUN
gs-3921	444	12	and	and	CCONJ
gs-3921	444	13	drug	drug	NOUN
gs-3921	444	14	response	response	NOUN
gs-3921	444	15	variability	variability	NOUN
gs-3921	444	16	,	,	PUNCT
gs-3921	444	17	elucidating	elucidating	NOUN
gs-3921	444	18	mechanisms	mechanism	NOUN
gs-3921	444	19	underlying	underlie	VERB
gs-3921	444	20	medication	medication	NOUN
gs-3921	444	21	-	-	PUNCT
gs-3921	444	22	induced	induce	VERB
gs-3921	444	23	adverse	adverse	ADJ
gs-3921	444	24	effects	effect	NOUN
gs-3921	444	25	and	and	CCONJ
gs-3921	444	26	toxicities	toxicity	NOUN
gs-3921	444	27	.	.	PUNCT
gs-3921	445	1	this	this	DET
gs-3921	445	2	growing	grow	VERB
gs-3921	445	3	body	body	NOUN
gs-3921	445	4	of	of	ADP
gs-3921	445	5	knowledge	knowledge	NOUN
gs-3921	445	6	challenges	challenge	VERB
gs-3921	445	7	traditional	traditional	ADJ
gs-3921	445	8	“	"	PUNCT
gs-3921	445	9	one	one	NUM
gs-3921	445	10	-	-	PUNCT
gs-3921	445	11	size	size	NOUN
gs-3921	445	12	-	-	PUNCT
gs-3921	445	13	fits	fit	VERB
gs-3921	445	14	-	-	PUNCT
gs-3921	445	15	all	all	PRON
gs-3921	445	16	”	"	PUNCT
gs-3921	445	17	prescribing	prescribing	NOUN
gs-3921	445	18	paradigms	paradigm	NOUN
gs-3921	445	19	and	and	CCONJ
gs-3921	445	20	mandates	mandate	VERB
gs-3921	445	21	the	the	DET
gs-3921	445	22	incorporation	incorporation	NOUN
gs-3921	445	23	of	of	ADP
gs-3921	445	24	genetic	genetic	ADJ
gs-3921	445	25	,	,	PUNCT
gs-3921	445	26	environmental	environmental	ADJ
gs-3921	445	27	,	,	PUNCT
gs-3921	445	28	and	and	CCONJ
gs-3921	445	29	patient	patient	NOUN
gs-3921	445	30	-	-	PUNCT
gs-3921	445	31	specific	specific	ADJ
gs-3921	445	32	factors	factor	NOUN
gs-3921	445	33	into	into	ADP
gs-3921	445	34	therapeutic	therapeutic	ADJ
gs-3921	445	35	decision	decision	NOUN
gs-3921	445	36	-	-	PUNCT
gs-3921	445	37	making	making	NOUN
gs-3921	445	38	.	.	PUNCT
gs-3921	446	1	the	the	DET
gs-3921	446	2	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	446	3	variability	variability	NOUN
gs-3921	446	4	in	in	ADP
gs-3921	446	5	cytochrome	cytochrome	ADJ
gs-3921	446	6	p450	p450	NUM
gs-3921	446	7	enzymes	enzyme	NOUN
gs-3921	446	8	exemplifies	exemplify	VERB
gs-3921	446	9	the	the	DET
gs-3921	446	10	molecular	molecular	ADJ
gs-3921	446	11	complexity	complexity	NOUN
gs-3921	446	12	influencing	influence	VERB
gs-3921	446	13	drug	drug	NOUN
gs-3921	446	14	metabolism	metabolism	NOUN
gs-3921	446	15	.	.	PUNCT
gs-3921	447	1	the	the	DET
gs-3921	447	2	allelic	allelic	ADJ
gs-3921	447	3	diversity	diversity	NOUN
gs-3921	447	4	within	within	ADP
gs-3921	447	5	cyp2d6	cyp2d6	PROPN
gs-3921	447	6	,	,	PUNCT
gs-3921	447	7	cyp2c19	cyp2c19	NOUN
gs-3921	447	8	,	,	PUNCT
gs-3921	447	9	and	and	CCONJ
gs-3921	447	10	cyp3a5	cyp3a5	NOUN
gs-3921	447	11	genes	gene	NOUN
gs-3921	447	12	is	be	AUX
gs-3921	447	13	a	a	DET
gs-3921	447	14	principal	principal	ADJ
gs-3921	447	15	determinant	determinant	ADJ
gs-3921	447	16	of	of	ADP
gs-3921	447	17	phenotypic	phenotypic	ADJ
gs-3921	447	18	heterogeneity	heterogeneity	NOUN
gs-3921	447	19	ranging	range	VERB
gs-3921	447	20	from	from	ADP
gs-3921	447	21	poor	poor	ADJ
gs-3921	447	22	to	to	ADP
gs-3921	447	23	ultra	ultra	ADJ
gs-3921	447	24	-	-	ADJ
gs-3921	447	25	rapid	rapid	ADJ
gs-3921	447	26	metabolizers	metabolizer	NOUN
gs-3921	447	27	,	,	PUNCT
gs-3921	447	28	with	with	ADP
gs-3921	447	29	significant	significant	ADJ
gs-3921	447	30	implications	implication	NOUN
gs-3921	447	31	for	for	ADP
gs-3921	447	32	drug	drug	NOUN
gs-3921	447	33	plasma	plasma	NOUN
gs-3921	447	34	levels	level	NOUN
gs-3921	447	35	,	,	PUNCT
gs-3921	447	36	efficacy	efficacy	NOUN
gs-3921	447	37	,	,	PUNCT
gs-3921	447	38	and	and	CCONJ
gs-3921	447	39	safety	safety	NOUN
gs-3921	447	40	.	.	PUNCT
gs-3921	448	1	clinical	clinical	ADJ
gs-3921	448	2	implementation	implementation	NOUN
gs-3921	448	3	of	of	ADP
gs-3921	448	4	genotype	genotype	NOUN
gs-3921	448	5	-	-	PUNCT
gs-3921	448	6	guided	guide	VERB
gs-3921	448	7	dosing	dosing	NOUN
gs-3921	448	8	has	have	AUX
gs-3921	448	9	demonstrated	demonstrate	VERB
gs-3921	448	10	reductions	reduction	NOUN
gs-3921	448	11	in	in	ADP
gs-3921	448	12	adverse	adverse	ADJ
gs-3921	448	13	drug	drug	NOUN
gs-3921	448	14	events	event	NOUN
gs-3921	448	15	and	and	CCONJ
gs-3921	448	16	improved	improve	VERB
gs-3921	448	17	therapeutic	therapeutic	ADJ
gs-3921	448	18	outcomes	outcome	NOUN
gs-3921	448	19	in	in	ADP
gs-3921	448	20	diverse	diverse	ADJ
gs-3921	448	21	populations	population	NOUN
gs-3921	448	22	,	,	PUNCT
gs-3921	448	23	yet	yet	CCONJ
gs-3921	448	24	its	its	PRON
gs-3921	448	25	full	full	ADJ
gs-3921	448	26	potential	potential	NOUN
gs-3921	448	27	remains	remain	VERB
gs-3921	448	28	unrealized	unrealized	ADJ
gs-3921	448	29	due	due	ADP
gs-3921	448	30	to	to	ADP
gs-3921	448	31	barriers	barrier	NOUN
gs-3921	448	32	in	in	ADP
gs-3921	448	33	clinical	clinical	ADJ
gs-3921	448	34	adoption	adoption	NOUN
gs-3921	448	35	.	.	PUNCT
gs-3921	449	1	these	these	DET
gs-3921	449	2	findings	finding	NOUN
gs-3921	449	3	advocate	advocate	VERB
gs-3921	449	4	for	for	ADP
gs-3921	449	5	routine	routine	ADJ
gs-3921	449	6	preemptive	preemptive	ADJ
gs-3921	449	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	449	8	screening	screening	NOUN
gs-3921	449	9	in	in	ADP
gs-3921	449	10	high	high	ADJ
gs-3921	449	11	-	-	PUNCT
gs-3921	449	12	risk	risk	NOUN
gs-3921	449	13	medications	medication	NOUN
gs-3921	449	14	and	and	CCONJ
gs-3921	449	15	populations	population	NOUN
gs-3921	449	16	,	,	PUNCT
gs-3921	449	17	accompanied	accompany	VERB
gs-3921	449	18	by	by	ADP
gs-3921	449	19	comprehensive	comprehensive	ADJ
gs-3921	449	20	clinician	clinician	NOUN
gs-3921	449	21	education	education	NOUN
gs-3921	449	22	to	to	PART
gs-3921	449	23	bridge	bridge	VERB
gs-3921	449	24	the	the	DET
gs-3921	449	25	knowledge	knowledge	NOUN
gs-3921	449	26	translation	translation	NOUN
gs-3921	449	27	gap	gap	NOUN
gs-3921	449	28	.	.	PUNCT
gs-3921	450	1	the	the	DET
gs-3921	450	2	role	role	NOUN
gs-3921	450	3	of	of	ADP
gs-3921	450	4	immune	immune	NOUN
gs-3921	450	5	-	-	PUNCT
gs-3921	450	6	related	relate	VERB
gs-3921	450	7	genetic	genetic	ADJ
gs-3921	450	8	markers	marker	NOUN
gs-3921	450	9	,	,	PUNCT
gs-3921	450	10	particularly	particularly	ADV
gs-3921	450	11	hla	hla	NOUN
gs-3921	450	12	alleles	allele	NOUN
gs-3921	450	13	,	,	PUNCT
gs-3921	450	14	in	in	ADP
gs-3921	450	15	mediating	mediate	VERB
gs-3921	450	16	severe	severe	ADJ
gs-3921	450	17	hypersensitivity	hypersensitivity	NOUN
gs-3921	450	18	reactions	reaction	NOUN
gs-3921	450	19	represents	represent	VERB
gs-3921	450	20	another	another	DET
gs-3921	450	21	critical	critical	ADJ
gs-3921	450	22	dimension	dimension	NOUN
gs-3921	450	23	.	.	PUNCT
gs-3921	451	1	the	the	DET
gs-3921	451	2	regional	regional	ADJ
gs-3921	451	3	and	and	CCONJ
gs-3921	451	4	ethnic	ethnic	ADJ
gs-3921	451	5	variability	variability	NOUN
gs-3921	451	6	in	in	ADP
gs-3921	451	7	hla	hla	PROPN
gs-3921	451	8	allele	allele	NOUN
gs-3921	451	9	frequencies	frequency	NOUN
gs-3921	451	10	necessitates	necessitate	VERB
gs-3921	451	11	context	context	NOUN
gs-3921	451	12	-	-	PUNCT
gs-3921	451	13	specific	specific	ADJ
gs-3921	451	14	screening	screening	NOUN
gs-3921	451	15	guidelines	guideline	NOUN
gs-3921	451	16	.	.	PUNCT
gs-3921	452	1	for	for	ADP
gs-3921	452	2	instance	instance	NOUN
gs-3921	452	3	,	,	PUNCT
gs-3921	452	4	while	while	SCONJ
gs-3921	452	5	hla	hla	NOUN
gs-3921	452	6	-	-	PUNCT
gs-3921	452	7	b*15:02	b*15:02	NOUN
gs-3921	452	8	testing	testing	NOUN
gs-3921	452	9	is	be	AUX
gs-3921	452	10	well	well	ADV
gs-3921	452	11	established	establish	VERB
gs-3921	452	12	in	in	ADP
gs-3921	452	13	southeast	southeast	PROPN
gs-3921	452	14	asia	asia	PROPN
gs-3921	452	15	,	,	PUNCT
gs-3921	452	16	emerging	emerge	VERB
gs-3921	452	17	evidence	evidence	NOUN
gs-3921	452	18	suggests	suggest	VERB
gs-3921	452	19	expanding	expand	VERB
gs-3921	452	20	genetic	genetic	ADJ
gs-3921	452	21	screening	screening	NOUN
gs-3921	452	22	in	in	ADP
gs-3921	452	23	other	other	ADJ
gs-3921	452	24	populations	population	NOUN
gs-3921	452	25	may	may	AUX
gs-3921	452	26	further	far	ADV
gs-3921	452	27	reduce	reduce	VERB
gs-3921	452	28	incidences	incidence	NOUN
gs-3921	452	29	of	of	ADP
gs-3921	452	30	stevens	stevens	PROPN
gs-3921	452	31	-	-	PUNCT
gs-3921	452	32	johnson	johnson	PROPN
gs-3921	452	33	syndrome	syndrome	PROPN
gs-3921	452	34	and	and	CCONJ
gs-3921	452	35	toxic	toxic	ADJ
gs-3921	452	36	epidermal	epidermal	ADJ
gs-3921	452	37	necrolysis	necrolysis	NOUN
gs-3921	452	38	.	.	PUNCT
gs-3921	453	1	this	this	PRON
gs-3921	453	2	underscores	underscore	VERB
gs-3921	453	3	the	the	DET
gs-3921	453	4	need	need	NOUN
gs-3921	453	5	for	for	ADP
gs-3921	453	6	dynamic	dynamic	ADJ
gs-3921	453	7	,	,	PUNCT
gs-3921	453	8	population	population	NOUN
gs-3921	453	9	-	-	PUNCT
gs-3921	453	10	tailored	tailor	VERB
gs-3921	453	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	453	12	policies	policy	NOUN
gs-3921	453	13	supported	support	VERB
gs-3921	453	14	by	by	ADP
gs-3921	453	15	robust	robust	ADJ
gs-3921	453	16	epidemiological	epidemiological	ADJ
gs-3921	453	17	surveillance	surveillance	NOUN
gs-3921	453	18	.	.	PUNCT
gs-3921	454	1	georgian	georgian	ADJ
gs-3921	454	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	454	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	454	4	ტ.	ტ.	VERB
gs-3921	454	5	7	7	NUM
gs-3921	454	6	n	n	DET
gs-3921	454	7	3	3	NUM
gs-3921	454	8	,	,	PUNCT
gs-3921	454	9	2025	2025	NUM
gs-3921	454	10	244	244	NUM
gs-3921	454	11	despite	despite	SCONJ
gs-3921	454	12	clear	clear	ADJ
gs-3921	454	13	scientific	scientific	ADJ
gs-3921	454	14	advances	advance	NOUN
gs-3921	454	15	,	,	PUNCT
gs-3921	454	16	the	the	DET
gs-3921	454	17	real	real	ADJ
gs-3921	454	18	-	-	PUNCT
gs-3921	454	19	world	world	NOUN
gs-3921	454	20	translation	translation	NOUN
gs-3921	454	21	of	of	ADP
gs-3921	454	22	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	454	23	is	be	AUX
gs-3921	454	24	impeded	impede	VERB
gs-3921	454	25	by	by	ADP
gs-3921	454	26	multifactorial	multifactorial	ADJ
gs-3921	454	27	challenges	challenge	NOUN
gs-3921	454	28	.	.	PUNCT
gs-3921	455	1	from	from	ADP
gs-3921	455	2	a	a	DET
gs-3921	455	3	systems	system	NOUN
gs-3921	455	4	perspective	perspective	NOUN
gs-3921	455	5	,	,	PUNCT
gs-3921	455	6	the	the	DET
gs-3921	455	7	lack	lack	NOUN
gs-3921	455	8	of	of	ADP
gs-3921	455	9	integration	integration	NOUN
gs-3921	455	10	into	into	ADP
gs-3921	455	11	existing	exist	VERB
gs-3921	455	12	electronic	electronic	ADJ
gs-3921	455	13	health	health	NOUN
gs-3921	455	14	record	record	NOUN
gs-3921	455	15	infrastructures	infrastructure	NOUN
gs-3921	455	16	restricts	restrict	VERB
gs-3921	455	17	the	the	DET
gs-3921	455	18	clinical	clinical	ADJ
gs-3921	455	19	utility	utility	NOUN
gs-3921	455	20	of	of	ADP
gs-3921	455	21	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	455	22	data	datum	NOUN
gs-3921	455	23	.	.	PUNCT
gs-3921	456	1	without	without	ADP
gs-3921	456	2	seamless	seamless	ADJ
gs-3921	456	3	access	access	NOUN
gs-3921	456	4	and	and	CCONJ
gs-3921	456	5	interpretive	interpretive	ADJ
gs-3921	456	6	support	support	NOUN
gs-3921	456	7	,	,	PUNCT
gs-3921	456	8	clinicians	clinician	NOUN
gs-3921	456	9	face	face	VERB
gs-3921	456	10	cognitive	cognitive	ADJ
gs-3921	456	11	and	and	CCONJ
gs-3921	456	12	operational	operational	ADJ
gs-3921	456	13	burdens	burden	NOUN
gs-3921	456	14	that	that	PRON
gs-3921	456	15	limit	limit	VERB
gs-3921	456	16	application	application	NOUN
gs-3921	456	17	.	.	PUNCT
gs-3921	457	1	the	the	DET
gs-3921	457	2	design	design	NOUN
gs-3921	457	3	and	and	CCONJ
gs-3921	457	4	implementation	implementation	NOUN
gs-3921	457	5	of	of	ADP
gs-3921	457	6	sophisticated	sophisticated	ADJ
gs-3921	457	7	clinical	clinical	ADJ
gs-3921	457	8	decision	decision	NOUN
gs-3921	457	9	support	support	NOUN
gs-3921	457	10	systems	system	NOUN
gs-3921	457	11	capable	capable	ADJ
gs-3921	457	12	of	of	ADP
gs-3921	457	13	delivering	deliver	VERB
gs-3921	457	14	actionable	actionable	ADJ
gs-3921	457	15	,	,	PUNCT
gs-3921	457	16	patientspecific	patientspecific	ADJ
gs-3921	457	17	recommendations	recommendation	NOUN
gs-3921	457	18	at	at	ADP
gs-3921	457	19	the	the	DET
gs-3921	457	20	point	point	NOUN
gs-3921	457	21	of	of	ADP
gs-3921	457	22	care	care	NOUN
gs-3921	457	23	are	be	AUX
gs-3921	457	24	critical	critical	ADJ
gs-3921	457	25	to	to	ADP
gs-3921	457	26	overcoming	overcome	VERB
gs-3921	457	27	these	these	DET
gs-3921	457	28	obstacles	obstacle	NOUN
gs-3921	457	29	.	.	PUNCT
gs-3921	458	1	patient	patient	ADJ
gs-3921	458	2	engagement	engagement	NOUN
gs-3921	458	3	and	and	CCONJ
gs-3921	458	4	health	health	NOUN
gs-3921	458	5	literacy	literacy	NOUN
gs-3921	458	6	emerge	emerge	VERB
gs-3921	458	7	as	as	ADP
gs-3921	458	8	pivotal	pivotal	ADJ
gs-3921	458	9	determinants	determinant	NOUN
gs-3921	458	10	of	of	ADP
gs-3921	458	11	successful	successful	ADJ
gs-3921	458	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	458	13	implementation	implementation	NOUN
gs-3921	458	14	.	.	PUNCT
gs-3921	459	1	the	the	DET
gs-3921	459	2	complexity	complexity	NOUN
gs-3921	459	3	of	of	ADP
gs-3921	459	4	genetic	genetic	ADJ
gs-3921	459	5	information	information	NOUN
gs-3921	459	6	requires	require	VERB
gs-3921	459	7	innovative	innovative	ADJ
gs-3921	459	8	,	,	PUNCT
gs-3921	459	9	culturally	culturally	ADV
gs-3921	459	10	sensitive	sensitive	ADJ
gs-3921	459	11	educational	educational	ADJ
gs-3921	459	12	interventions	intervention	NOUN
gs-3921	459	13	tailored	tailor	VERB
gs-3921	459	14	to	to	PART
gs-3921	459	15	diverse	diverse	VERB
gs-3921	459	16	populations	population	NOUN
gs-3921	459	17	.	.	PUNCT
gs-3921	460	1	concerns	concern	NOUN
gs-3921	460	2	regarding	regard	VERB
gs-3921	460	3	genetic	genetic	ADJ
gs-3921	460	4	privacy	privacy	NOUN
gs-3921	460	5	,	,	PUNCT
gs-3921	460	6	potential	potential	ADJ
gs-3921	460	7	stigmatization	stigmatization	NOUN
gs-3921	460	8	,	,	PUNCT
gs-3921	460	9	and	and	CCONJ
gs-3921	460	10	discrimination	discrimination	NOUN
gs-3921	460	11	remain	remain	VERB
gs-3921	460	12	prevalent	prevalent	ADJ
gs-3921	460	13	.	.	PUNCT
gs-3921	461	1	transparent	transparent	ADJ
gs-3921	461	2	communication	communication	NOUN
gs-3921	461	3	strategies	strategy	NOUN
gs-3921	461	4	and	and	CCONJ
gs-3921	461	5	robust	robust	ADJ
gs-3921	461	6	legal	legal	ADJ
gs-3921	461	7	protections	protection	NOUN
gs-3921	461	8	must	must	AUX
gs-3921	461	9	be	be	AUX
gs-3921	461	10	emphasized	emphasize	VERB
gs-3921	461	11	to	to	PART
gs-3921	461	12	foster	foster	VERB
gs-3921	461	13	trust	trust	NOUN
gs-3921	461	14	and	and	CCONJ
gs-3921	461	15	informed	informed	ADJ
gs-3921	461	16	participation	participation	NOUN
gs-3921	461	17	.	.	PUNCT
gs-3921	462	1	furthermore	furthermore	ADV
gs-3921	462	2	,	,	PUNCT
gs-3921	462	3	equitable	equitable	ADJ
gs-3921	462	4	access	access	NOUN
gs-3921	462	5	to	to	ADP
gs-3921	462	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	462	7	services	service	NOUN
gs-3921	462	8	demands	demand	VERB
gs-3921	462	9	addressing	address	VERB
gs-3921	462	10	disparities	disparity	NOUN
gs-3921	462	11	in	in	ADP
gs-3921	462	12	healthcare	healthcare	PROPN
gs-3921	462	13	infrastructure	infrastructure	NOUN
gs-3921	462	14	,	,	PUNCT
gs-3921	462	15	provider	provider	NOUN
gs-3921	462	16	availability	availability	NOUN
gs-3921	462	17	,	,	PUNCT
gs-3921	462	18	and	and	CCONJ
gs-3921	462	19	socioeconomic	socioeconomic	ADJ
gs-3921	462	20	determinants	determinant	NOUN
gs-3921	462	21	.	.	PUNCT
gs-3921	463	1	the	the	DET
gs-3921	463	2	synergy	synergy	NOUN
gs-3921	463	3	between	between	ADP
gs-3921	463	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	463	5	and	and	CCONJ
gs-3921	463	6	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	463	7	represents	represent	VERB
gs-3921	463	8	a	a	DET
gs-3921	463	9	frontier	frontier	NOUN
gs-3921	463	10	for	for	ADP
gs-3921	463	11	enhancing	enhance	VERB
gs-3921	463	12	medication	medication	NOUN
gs-3921	463	13	safety	safety	NOUN
gs-3921	463	14	.	.	PUNCT
gs-3921	464	1	integrating	integrate	VERB
gs-3921	464	2	genetic	genetic	ADJ
gs-3921	464	3	risk	risk	NOUN
gs-3921	464	4	stratification	stratification	NOUN
gs-3921	464	5	into	into	ADP
gs-3921	464	6	active	active	ADJ
gs-3921	464	7	surveillance	surveillance	NOUN
gs-3921	464	8	programs	program	NOUN
gs-3921	464	9	refines	refine	VERB
gs-3921	464	10	signal	signal	ADJ
gs-3921	464	11	detection	detection	NOUN
gs-3921	464	12	,	,	PUNCT
gs-3921	464	13	enabling	enable	VERB
gs-3921	464	14	earlier	early	ADJ
gs-3921	464	15	identification	identification	NOUN
gs-3921	464	16	of	of	ADP
gs-3921	464	17	susceptible	susceptible	ADJ
gs-3921	464	18	subpopulations	subpopulation	NOUN
gs-3921	464	19	.	.	PUNCT
gs-3921	465	1	real	real	ADJ
gs-3921	465	2	-	-	PUNCT
gs-3921	465	3	world	world	NOUN
gs-3921	465	4	data	datum	NOUN
gs-3921	465	5	repositories	repository	NOUN
gs-3921	465	6	enriched	enrich	VERB
gs-3921	465	7	with	with	ADP
gs-3921	465	8	genomic	genomic	ADJ
gs-3921	465	9	information	information	NOUN
gs-3921	465	10	and	and	CCONJ
gs-3921	465	11	analyzed	analyze	VERB
gs-3921	465	12	through	through	ADP
gs-3921	465	13	advanced	advanced	ADJ
gs-3921	465	14	machine	machine	NOUN
gs-3921	465	15	learning	learn	VERB
gs-3921	465	16	algorithms	algorithm	NOUN
gs-3921	465	17	offer	offer	VERB
gs-3921	465	18	unprecedented	unprecedented	ADJ
gs-3921	465	19	opportunities	opportunity	NOUN
gs-3921	465	20	for	for	ADP
gs-3921	465	21	dynamic	dynamic	ADJ
gs-3921	465	22	monitoring	monitoring	NOUN
gs-3921	465	23	and	and	CCONJ
gs-3921	465	24	adaptive	adaptive	ADJ
gs-3921	465	25	risk	risk	NOUN
gs-3921	465	26	management	management	NOUN
gs-3921	465	27	.	.	PUNCT
gs-3921	466	1	however	however	ADV
gs-3921	466	2	,	,	PUNCT
gs-3921	466	3	ensuring	ensure	VERB
gs-3921	466	4	data	datum	NOUN
gs-3921	466	5	standardization	standardization	NOUN
gs-3921	466	6	,	,	PUNCT
gs-3921	466	7	interoperability	interoperability	NOUN
gs-3921	466	8	,	,	PUNCT
gs-3921	466	9	and	and	CCONJ
gs-3921	466	10	patient	patient	ADJ
gs-3921	466	11	confidentiality	confidentiality	NOUN
gs-3921	466	12	within	within	ADP
gs-3921	466	13	these	these	DET
gs-3921	466	14	systems	system	NOUN
gs-3921	466	15	requires	require	VERB
gs-3921	466	16	coordinated	coordinate	VERB
gs-3921	466	17	governance	governance	NOUN
gs-3921	466	18	frameworks	framework	NOUN
gs-3921	466	19	and	and	CCONJ
gs-3921	466	20	ethical	ethical	ADJ
gs-3921	466	21	oversight	oversight	NOUN
gs-3921	466	22	.	.	PUNCT
gs-3921	467	1	polypharmacy	polypharmacy	NOUN
gs-3921	467	2	,	,	PUNCT
gs-3921	467	3	a	a	DET
gs-3921	467	4	prevalent	prevalent	ADJ
gs-3921	467	5	challenge	challenge	NOUN
gs-3921	467	6	in	in	ADP
gs-3921	467	7	contemporary	contemporary	ADJ
gs-3921	467	8	medicine	medicine	NOUN
gs-3921	467	9	,	,	PUNCT
gs-3921	467	10	particularly	particularly	ADV
gs-3921	467	11	among	among	ADP
gs-3921	467	12	the	the	DET
gs-3921	467	13	elderly	elderly	ADJ
gs-3921	467	14	and	and	CCONJ
gs-3921	467	15	chronically	chronically	ADV
gs-3921	467	16	ill	ill	ADJ
gs-3921	467	17	,	,	PUNCT
gs-3921	467	18	intensifies	intensify	VERB
gs-3921	467	19	the	the	DET
gs-3921	467	20	risk	risk	NOUN
gs-3921	467	21	of	of	ADP
gs-3921	467	22	adverse	adverse	ADJ
gs-3921	467	23	drug	drug	NOUN
gs-3921	467	24	reactions	reaction	NOUN
gs-3921	467	25	.	.	PUNCT
gs-3921	468	1	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	468	2	provides	provide	VERB
gs-3921	468	3	a	a	DET
gs-3921	468	4	critical	critical	ADJ
gs-3921	468	5	lens	lens	NOUN
gs-3921	468	6	for	for	ADP
gs-3921	468	7	disentangling	disentangle	VERB
gs-3921	468	8	the	the	DET
gs-3921	468	9	complexity	complexity	NOUN
gs-3921	468	10	of	of	ADP
gs-3921	468	11	drug	drug	NOUN
gs-3921	468	12	-	-	PUNCT
gs-3921	468	13	drug	drug	NOUN
gs-3921	468	14	and	and	CCONJ
gs-3921	468	15	drug	drug	NOUN
gs-3921	468	16	-	-	PUNCT
gs-3921	468	17	gene	gene	NOUN
gs-3921	468	18	interactions	interaction	NOUN
gs-3921	468	19	.	.	PUNCT
gs-3921	469	1	multidisciplinary	multidisciplinary	ADJ
gs-3921	469	2	medication	medication	NOUN
gs-3921	469	3	management	management	NOUN
gs-3921	469	4	teams	team	NOUN
gs-3921	469	5	incorporating	incorporate	VERB
gs-3921	469	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	469	7	expertise	expertise	NOUN
gs-3921	469	8	can	can	AUX
gs-3921	469	9	tailor	tailor	VERB
gs-3921	469	10	regimens	regimen	NOUN
gs-3921	469	11	to	to	ADP
gs-3921	469	12	individual	individual	ADJ
gs-3921	469	13	metabolic	metabolic	NOUN
gs-3921	469	14	profiles	profile	NOUN
gs-3921	469	15	,	,	PUNCT
gs-3921	469	16	mitigating	mitigate	VERB
gs-3921	469	17	toxicity	toxicity	NOUN
gs-3921	469	18	risks	risk	NOUN
gs-3921	469	19	and	and	CCONJ
gs-3921	469	20	enhancing	enhance	VERB
gs-3921	469	21	therapeutic	therapeutic	ADJ
gs-3921	469	22	efficacy	efficacy	NOUN
gs-3921	469	23	.	.	PUNCT
gs-3921	470	1	development	development	NOUN
gs-3921	470	2	of	of	ADP
gs-3921	470	3	integrated	integrate	VERB
gs-3921	470	4	informatics	informatic	NOUN
gs-3921	470	5	platforms	platform	NOUN
gs-3921	470	6	synthesizing	synthesize	VERB
gs-3921	470	7	genetic	genetic	ADJ
gs-3921	470	8	,	,	PUNCT
gs-3921	470	9	clinical	clinical	ADJ
gs-3921	470	10	,	,	PUNCT
gs-3921	470	11	and	and	CCONJ
gs-3921	470	12	pharmacological	pharmacological	ADJ
gs-3921	470	13	data	datum	NOUN
gs-3921	470	14	will	will	AUX
gs-3921	470	15	be	be	AUX
gs-3921	470	16	instrumental	instrumental	ADJ
gs-3921	470	17	in	in	ADP
gs-3921	470	18	operationalizing	operationalize	VERB
gs-3921	470	19	this	this	DET
gs-3921	470	20	personalized	personalized	ADJ
gs-3921	470	21	approach	approach	NOUN
gs-3921	470	22	.	.	PUNCT
gs-3921	471	1	beyond	beyond	ADP
gs-3921	471	2	single	single	ADJ
gs-3921	471	3	-	-	PUNCT
gs-3921	471	4	gene	gene	NOUN
gs-3921	471	5	associations	association	NOUN
gs-3921	471	6	,	,	PUNCT
gs-3921	471	7	the	the	DET
gs-3921	471	8	emergence	emergence	NOUN
gs-3921	471	9	of	of	ADP
gs-3921	471	10	multi	multi	ADJ
gs-3921	471	11	-	-	ADJ
gs-3921	471	12	omics	omics	ADJ
gs-3921	471	13	and	and	CCONJ
gs-3921	471	14	systems	system	NOUN
gs-3921	471	15	pharmacology	pharmacology	NOUN
gs-3921	471	16	heralds	herald	VERB
gs-3921	471	17	a	a	DET
gs-3921	471	18	more	more	ADV
gs-3921	471	19	holistic	holistic	ADJ
gs-3921	471	20	understanding	understanding	NOUN
gs-3921	471	21	of	of	ADP
gs-3921	471	22	drug	drug	NOUN
gs-3921	471	23	response	response	NOUN
gs-3921	471	24	.	.	PUNCT
gs-3921	472	1	epigenomic	epigenomic	ADJ
gs-3921	472	2	modifications	modification	NOUN
gs-3921	472	3	,	,	PUNCT
gs-3921	472	4	transcriptomic	transcriptomic	ADJ
gs-3921	472	5	fluctuations	fluctuation	NOUN
gs-3921	472	6	,	,	PUNCT
gs-3921	472	7	proteomic	proteomic	ADJ
gs-3921	472	8	changes	change	NOUN
gs-3921	472	9	,	,	PUNCT
gs-3921	472	10	and	and	CCONJ
gs-3921	472	11	metabolomic	metabolomic	ADJ
gs-3921	472	12	profiles	profile	NOUN
gs-3921	472	13	collectively	collectively	ADV
gs-3921	472	14	influence	influence	VERB
gs-3921	472	15	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	472	16	and	and	CCONJ
gs-3921	472	17	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	472	18	.	.	PUNCT
gs-3921	473	1	harnessing	harness	VERB
gs-3921	473	2	these	these	DET
gs-3921	473	3	complex	complex	ADJ
gs-3921	473	4	data	datum	NOUN
gs-3921	473	5	streams	stream	VERB
gs-3921	473	6	through	through	ADP
gs-3921	473	7	artificial	artificial	ADJ
gs-3921	473	8	intelligence	intelligence	NOUN
gs-3921	473	9	-	-	PUNCT
gs-3921	473	10	driven	drive	VERB
gs-3921	473	11	analytics	analytic	NOUN
gs-3921	473	12	can	can	AUX
gs-3921	473	13	identify	identify	VERB
gs-3921	473	14	novel	novel	ADJ
gs-3921	473	15	biomarkers	biomarker	NOUN
gs-3921	473	16	and	and	CCONJ
gs-3921	473	17	predictive	predictive	ADJ
gs-3921	473	18	signatures	signature	NOUN
gs-3921	473	19	,	,	PUNCT
gs-3921	473	20	facilitating	facilitate	VERB
gs-3921	473	21	earlier	early	ADJ
gs-3921	473	22	detection	detection	NOUN
gs-3921	473	23	of	of	ADP
gs-3921	473	24	toxicity	toxicity	NOUN
gs-3921	473	25	and	and	CCONJ
gs-3921	473	26	individualizing	individualize	VERB
gs-3921	473	27	therapy	therapy	NOUN
gs-3921	473	28	.	.	PUNCT
gs-3921	474	1	yet	yet	ADV
gs-3921	474	2	,	,	PUNCT
gs-3921	474	3	these	these	DET
gs-3921	474	4	advances	advance	NOUN
gs-3921	474	5	also	also	ADV
gs-3921	474	6	introduce	introduce	VERB
gs-3921	474	7	challenges	challenge	NOUN
gs-3921	474	8	in	in	ADP
gs-3921	474	9	data	datum	NOUN
gs-3921	474	10	management	management	NOUN
gs-3921	474	11	,	,	PUNCT
gs-3921	474	12	interpretability	interpretability	NOUN
gs-3921	474	13	,	,	PUNCT
gs-3921	474	14	and	and	CCONJ
gs-3921	474	15	clinical	clinical	ADJ
gs-3921	474	16	validation	validation	NOUN
gs-3921	474	17	,	,	PUNCT
gs-3921	474	18	necessitating	necessitate	VERB
gs-3921	474	19	interdisciplinary	interdisciplinary	ADJ
gs-3921	474	20	collaboration	collaboration	NOUN
gs-3921	474	21	and	and	CCONJ
gs-3921	474	22	methodological	methodological	ADJ
gs-3921	474	23	rigor	rigor	NOUN
gs-3921	474	24	.	.	PUNCT
gs-3921	475	1	georgian	georgian	ADJ
gs-3921	475	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	475	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	475	4	ტ.	ტ.	VERB
gs-3921	475	5	7	7	NUM
gs-3921	475	6	n	n	PRON
gs-3921	475	7	3	3	NUM
gs-3921	475	8	,	,	PUNCT
gs-3921	475	9	2025	2025	NUM
gs-3921	475	10	245	245	NUM
gs-3921	475	11	technological	technological	ADJ
gs-3921	475	12	innovations	innovation	NOUN
gs-3921	475	13	,	,	PUNCT
gs-3921	475	14	including	include	VERB
gs-3921	475	15	blockchain	blockchain	NOUN
gs-3921	475	16	for	for	ADP
gs-3921	475	17	secure	secure	ADJ
gs-3921	475	18	data	datum	NOUN
gs-3921	475	19	sharing	sharing	NOUN
gs-3921	475	20	,	,	PUNCT
gs-3921	475	21	wearable	wearable	ADJ
gs-3921	475	22	biosensors	biosensor	NOUN
gs-3921	475	23	for	for	ADP
gs-3921	475	24	real	real	ADJ
gs-3921	475	25	-	-	PUNCT
gs-3921	475	26	time	time	NOUN
gs-3921	475	27	monitoring	monitoring	NOUN
gs-3921	475	28	,	,	PUNCT
gs-3921	475	29	and	and	CCONJ
gs-3921	475	30	telemedicine	telemedicine	NOUN
gs-3921	475	31	platforms	platform	NOUN
gs-3921	475	32	for	for	ADP
gs-3921	475	33	genetic	genetic	ADJ
gs-3921	475	34	counseling	counseling	NOUN
gs-3921	475	35	,	,	PUNCT
gs-3921	475	36	hold	hold	VERB
gs-3921	475	37	promise	promise	NOUN
gs-3921	475	38	in	in	ADP
gs-3921	475	39	addressing	address	VERB
gs-3921	475	40	logistical	logistical	ADJ
gs-3921	475	41	and	and	CCONJ
gs-3921	475	42	ethical	ethical	ADJ
gs-3921	475	43	challenges	challenge	NOUN
gs-3921	475	44	.	.	PUNCT
gs-3921	476	1	their	their	PRON
gs-3921	476	2	successful	successful	ADJ
gs-3921	476	3	deployment	deployment	NOUN
gs-3921	476	4	depends	depend	VERB
gs-3921	476	5	on	on	ADP
gs-3921	476	6	rigorous	rigorous	ADJ
gs-3921	476	7	evaluation	evaluation	NOUN
gs-3921	476	8	,	,	PUNCT
gs-3921	476	9	patient	patient	NOUN
gs-3921	476	10	-	-	PUNCT
gs-3921	476	11	centered	center	VERB
gs-3921	476	12	design	design	NOUN
gs-3921	476	13	,	,	PUNCT
gs-3921	476	14	and	and	CCONJ
gs-3921	476	15	policy	policy	NOUN
gs-3921	476	16	alignment	alignment	NOUN
gs-3921	476	17	.	.	PUNCT
gs-3921	477	1	globally	globally	ADV
gs-3921	477	2	,	,	PUNCT
gs-3921	477	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	477	4	implementation	implementation	NOUN
gs-3921	477	5	must	must	AUX
gs-3921	477	6	be	be	AUX
gs-3921	477	7	contextualized	contextualize	VERB
gs-3921	477	8	within	within	ADP
gs-3921	477	9	diverse	diverse	ADJ
gs-3921	477	10	healthcare	healthcare	NOUN
gs-3921	477	11	infrastructures	infrastructure	NOUN
gs-3921	477	12	,	,	PUNCT
gs-3921	477	13	genetic	genetic	ADJ
gs-3921	477	14	backgrounds	background	NOUN
gs-3921	477	15	,	,	PUNCT
gs-3921	477	16	and	and	CCONJ
gs-3921	477	17	cultural	cultural	ADJ
gs-3921	477	18	landscapes	landscape	NOUN
gs-3921	477	19	.	.	PUNCT
gs-3921	478	1	international	international	ADJ
gs-3921	478	2	collaboration	collaboration	NOUN
gs-3921	478	3	,	,	PUNCT
gs-3921	478	4	data	datum	NOUN
gs-3921	478	5	harmonization	harmonization	NOUN
gs-3921	478	6	,	,	PUNCT
gs-3921	478	7	and	and	CCONJ
gs-3921	478	8	capacity	capacity	NOUN
gs-3921	478	9	building	building	NOUN
gs-3921	478	10	are	be	AUX
gs-3921	478	11	essential	essential	ADJ
gs-3921	478	12	to	to	PART
gs-3921	478	13	realize	realize	VERB
gs-3921	478	14	equitable	equitable	ADJ
gs-3921	478	15	benefits	benefit	NOUN
gs-3921	478	16	.	.	PUNCT
gs-3921	479	1	the	the	DET
gs-3921	479	2	development	development	NOUN
gs-3921	479	3	of	of	ADP
gs-3921	479	4	adaptable	adaptable	ADJ
gs-3921	479	5	,	,	PUNCT
gs-3921	479	6	evidence	evidence	NOUN
gs-3921	479	7	-	-	PUNCT
gs-3921	479	8	based	base	VERB
gs-3921	479	9	guidelines	guideline	NOUN
gs-3921	479	10	and	and	CCONJ
gs-3921	479	11	regulatory	regulatory	ADJ
gs-3921	479	12	harmonization	harmonization	NOUN
gs-3921	479	13	will	will	AUX
gs-3921	479	14	facilitate	facilitate	VERB
gs-3921	479	15	cross	cross	ADJ
gs-3921	479	16	-	-	ADJ
gs-3921	479	17	border	border	ADJ
gs-3921	479	18	adoption	adoption	NOUN
gs-3921	479	19	and	and	CCONJ
gs-3921	479	20	innovation	innovation	NOUN
gs-3921	479	21	.	.	PUNCT
gs-3921	480	1	the	the	DET
gs-3921	480	2	integration	integration	NOUN
gs-3921	480	3	of	of	ADP
gs-3921	480	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	480	5	insights	insight	NOUN
gs-3921	480	6	with	with	ADP
gs-3921	480	7	patient	patient	NOUN
gs-3921	480	8	-	-	PUNCT
gs-3921	480	9	centered	center	VERB
gs-3921	480	10	care	care	NOUN
gs-3921	480	11	and	and	CCONJ
gs-3921	480	12	advanced	advanced	ADJ
gs-3921	480	13	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	480	14	represents	represent	VERB
gs-3921	480	15	a	a	DET
gs-3921	480	16	transformative	transformative	ADJ
gs-3921	480	17	opportunity	opportunity	NOUN
gs-3921	480	18	to	to	PART
gs-3921	480	19	enhance	enhance	VERB
gs-3921	480	20	medication	medication	NOUN
gs-3921	480	21	safety	safety	NOUN
gs-3921	480	22	and	and	CCONJ
gs-3921	480	23	therapeutic	therapeutic	ADJ
gs-3921	480	24	outcomes	outcome	NOUN
gs-3921	480	25	.	.	PUNCT
gs-3921	481	1	realizing	realize	VERB
gs-3921	481	2	this	this	DET
gs-3921	481	3	potential	potential	ADJ
gs-3921	481	4	demands	demand	NOUN
gs-3921	481	5	multidisciplinary	multidisciplinary	ADJ
gs-3921	481	6	,	,	PUNCT
gs-3921	481	7	multi	multi	ADJ
gs-3921	481	8	-	-	ADJ
gs-3921	481	9	stakeholder	stakeholder	ADJ
gs-3921	481	10	efforts	effort	NOUN
gs-3921	481	11	to	to	PART
gs-3921	481	12	surmount	surmount	VERB
gs-3921	481	13	scientific	scientific	ADJ
gs-3921	481	14	,	,	PUNCT
gs-3921	481	15	clinical	clinical	ADJ
gs-3921	481	16	,	,	PUNCT
gs-3921	481	17	ethical	ethical	ADJ
gs-3921	481	18	,	,	PUNCT
gs-3921	481	19	and	and	CCONJ
gs-3921	481	20	systemic	systemic	ADJ
gs-3921	481	21	barriers	barrier	NOUN
gs-3921	481	22	.	.	PUNCT
gs-3921	482	1	the	the	DET
gs-3921	482	2	convergence	convergence	NOUN
gs-3921	482	3	of	of	ADP
gs-3921	482	4	technological	technological	ADJ
gs-3921	482	5	advances	advance	NOUN
gs-3921	482	6	,	,	PUNCT
gs-3921	482	7	policy	policy	NOUN
gs-3921	482	8	evolution	evolution	NOUN
gs-3921	482	9	,	,	PUNCT
gs-3921	482	10	and	and	CCONJ
gs-3921	482	11	patient	patient	ADJ
gs-3921	482	12	engagement	engagement	NOUN
gs-3921	482	13	sets	set	VERB
gs-3921	482	14	the	the	DET
gs-3921	482	15	stage	stage	NOUN
gs-3921	482	16	for	for	ADP
gs-3921	482	17	a	a	DET
gs-3921	482	18	new	new	ADJ
gs-3921	482	19	era	era	NOUN
gs-3921	482	20	of	of	ADP
gs-3921	482	21	precision	precision	NOUN
gs-3921	482	22	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	482	23	that	that	PRON
gs-3921	482	24	is	be	AUX
gs-3921	482	25	safer	safe	ADJ
gs-3921	482	26	,	,	PUNCT
gs-3921	482	27	more	more	ADV
gs-3921	482	28	effective	effective	ADJ
gs-3921	482	29	,	,	PUNCT
gs-3921	482	30	and	and	CCONJ
gs-3921	482	31	tailored	tailor	VERB
gs-3921	482	32	to	to	ADP
gs-3921	482	33	individual	individual	ADJ
gs-3921	482	34	needs	need	NOUN
gs-3921	482	35	.	.	PUNCT
gs-3921	483	1	the	the	DET
gs-3921	483	2	landscape	landscape	NOUN
gs-3921	483	3	of	of	ADP
gs-3921	483	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	483	5	and	and	CCONJ
gs-3921	483	6	patient	patient	NOUN
gs-3921	483	7	-	-	PUNCT
gs-3921	483	8	centered	center	VERB
gs-3921	483	9	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	483	10	continues	continue	VERB
gs-3921	483	11	to	to	PART
gs-3921	483	12	evolve	evolve	VERB
gs-3921	483	13	rapidly	rapidly	ADV
gs-3921	483	14	,	,	PUNCT
gs-3921	483	15	propelled	propel	VERB
gs-3921	483	16	by	by	ADP
gs-3921	483	17	advances	advance	NOUN
gs-3921	483	18	in	in	ADP
gs-3921	483	19	molecular	molecular	ADJ
gs-3921	483	20	biology	biology	NOUN
gs-3921	483	21	,	,	PUNCT
gs-3921	483	22	bioinformatics	bioinformatics	NOUN
gs-3921	483	23	,	,	PUNCT
gs-3921	483	24	and	and	CCONJ
gs-3921	483	25	clinical	clinical	ADJ
gs-3921	483	26	sciences	science	NOUN
gs-3921	483	27	.	.	PUNCT
gs-3921	484	1	this	this	DET
gs-3921	484	2	progression	progression	NOUN
gs-3921	484	3	reveals	reveal	VERB
gs-3921	484	4	increasingly	increasingly	ADV
gs-3921	484	5	complex	complex	ADJ
gs-3921	484	6	interdependencies	interdependency	NOUN
gs-3921	484	7	between	between	ADP
gs-3921	484	8	genetic	genetic	ADJ
gs-3921	484	9	makeup	makeup	NOUN
gs-3921	484	10	,	,	PUNCT
gs-3921	484	11	environmental	environmental	ADJ
gs-3921	484	12	exposures	exposure	NOUN
gs-3921	484	13	,	,	PUNCT
gs-3921	484	14	and	and	CCONJ
gs-3921	484	15	patient	patient	NOUN
gs-3921	484	16	-	-	PUNCT
gs-3921	484	17	specific	specific	ADJ
gs-3921	484	18	factors	factor	NOUN
gs-3921	484	19	that	that	PRON
gs-3921	484	20	modulate	modulate	VERB
gs-3921	484	21	drug	drug	NOUN
gs-3921	484	22	response	response	NOUN
gs-3921	484	23	and	and	CCONJ
gs-3921	484	24	toxicity	toxicity	NOUN
gs-3921	484	25	.	.	PUNCT
gs-3921	485	1	such	such	ADJ
gs-3921	485	2	intricacies	intricacy	NOUN
gs-3921	485	3	underscore	underscore	VERB
gs-3921	485	4	the	the	DET
gs-3921	485	5	insufficiency	insufficiency	NOUN
gs-3921	485	6	of	of	ADP
gs-3921	485	7	traditional	traditional	ADJ
gs-3921	485	8	prescribing	prescribing	NOUN
gs-3921	485	9	frameworks	framework	NOUN
gs-3921	485	10	and	and	CCONJ
gs-3921	485	11	highlight	highlight	VERB
gs-3921	485	12	the	the	DET
gs-3921	485	13	urgency	urgency	NOUN
gs-3921	485	14	of	of	ADP
gs-3921	485	15	embedding	embed	VERB
gs-3921	485	16	comprehensive	comprehensive	ADJ
gs-3921	485	17	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	485	18	data	datum	NOUN
gs-3921	485	19	into	into	ADP
gs-3921	485	20	personalized	personalized	ADJ
gs-3921	485	21	care	care	NOUN
gs-3921	485	22	models	model	NOUN
gs-3921	485	23	.	.	PUNCT
gs-3921	486	1	a	a	DET
gs-3921	486	2	salient	salient	ADJ
gs-3921	486	3	theme	theme	NOUN
gs-3921	486	4	emerging	emerge	VERB
gs-3921	486	5	from	from	ADP
gs-3921	486	6	contemporary	contemporary	ADJ
gs-3921	486	7	research	research	NOUN
gs-3921	486	8	is	be	AUX
gs-3921	486	9	the	the	DET
gs-3921	486	10	concept	concept	NOUN
gs-3921	486	11	of	of	ADP
gs-3921	486	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	486	13	heterogeneity	heterogeneity	NOUN
gs-3921	486	14	within	within	ADP
gs-3921	486	15	and	and	CCONJ
gs-3921	486	16	across	across	ADP
gs-3921	486	17	populations	population	NOUN
gs-3921	486	18	.	.	PUNCT
gs-3921	487	1	the	the	DET
gs-3921	487	2	allelic	allelic	ADJ
gs-3921	487	3	diversity	diversity	NOUN
gs-3921	487	4	observed	observe	VERB
gs-3921	487	5	in	in	ADP
gs-3921	487	6	drug	drug	NOUN
gs-3921	487	7	metabolism	metabolism	NOUN
gs-3921	487	8	and	and	CCONJ
gs-3921	487	9	immune	immune	ADJ
gs-3921	487	10	response	response	NOUN
gs-3921	487	11	genes	gene	NOUN
gs-3921	487	12	is	be	AUX
gs-3921	487	13	not	not	PART
gs-3921	487	14	uniformly	uniformly	ADV
gs-3921	487	15	distributed	distribute	VERB
gs-3921	487	16	but	but	CCONJ
gs-3921	487	17	reflects	reflect	VERB
gs-3921	487	18	ancestral	ancestral	ADJ
gs-3921	487	19	,	,	PUNCT
gs-3921	487	20	ethnic	ethnic	ADJ
gs-3921	487	21	,	,	PUNCT
gs-3921	487	22	and	and	CCONJ
gs-3921	487	23	geographic	geographic	ADJ
gs-3921	487	24	variations	variation	NOUN
gs-3921	487	25	.	.	PUNCT
gs-3921	488	1	this	this	DET
gs-3921	488	2	heterogeneity	heterogeneity	NOUN
gs-3921	488	3	complicates	complicate	VERB
gs-3921	488	4	the	the	DET
gs-3921	488	5	generalizability	generalizability	NOUN
gs-3921	488	6	of	of	ADP
gs-3921	488	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	488	8	findings	finding	NOUN
gs-3921	488	9	and	and	CCONJ
gs-3921	488	10	calls	call	VERB
gs-3921	488	11	for	for	ADP
gs-3921	488	12	more	more	ADJ
gs-3921	488	13	inclusive	inclusive	ADJ
gs-3921	488	14	research	research	NOUN
gs-3921	488	15	designs	design	NOUN
gs-3921	488	16	that	that	PRON
gs-3921	488	17	encompass	encompass	VERB
gs-3921	488	18	underrepresented	underrepresented	ADJ
gs-3921	488	19	populations	population	NOUN
gs-3921	488	20	.	.	PUNCT
gs-3921	489	1	current	current	ADJ
gs-3921	489	2	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	489	3	databases	database	NOUN
gs-3921	489	4	often	often	ADV
gs-3921	489	5	suffer	suffer	VERB
gs-3921	489	6	from	from	ADP
gs-3921	489	7	eurocentric	eurocentric	ADJ
gs-3921	489	8	biases	bias	NOUN
gs-3921	489	9	,	,	PUNCT
gs-3921	489	10	limiting	limit	VERB
gs-3921	489	11	the	the	DET
gs-3921	489	12	predictive	predictive	ADJ
gs-3921	489	13	power	power	NOUN
gs-3921	489	14	and	and	CCONJ
gs-3921	489	15	clinical	clinical	ADJ
gs-3921	489	16	applicability	applicability	NOUN
gs-3921	489	17	of	of	ADP
gs-3921	489	18	genotype	genotype	NOUN
gs-3921	489	19	-	-	PUNCT
gs-3921	489	20	guided	guide	VERB
gs-3921	489	21	therapies	therapy	NOUN
gs-3921	489	22	in	in	ADP
gs-3921	489	23	diverse	diverse	ADJ
gs-3921	489	24	demographic	demographic	ADJ
gs-3921	489	25	groups	group	NOUN
gs-3921	489	26	.	.	PUNCT
gs-3921	490	1	addressing	address	VERB
gs-3921	490	2	this	this	DET
gs-3921	490	3	gap	gap	NOUN
gs-3921	490	4	requires	require	VERB
gs-3921	490	5	concerted	concerted	ADJ
gs-3921	490	6	efforts	effort	NOUN
gs-3921	490	7	to	to	PART
gs-3921	490	8	expand	expand	VERB
gs-3921	490	9	genomic	genomic	ADJ
gs-3921	490	10	studies	study	NOUN
gs-3921	490	11	globally	globally	ADV
gs-3921	490	12	,	,	PUNCT
gs-3921	490	13	implement	implement	VERB
gs-3921	490	14	cross	cross	ADJ
gs-3921	490	15	-	-	ADJ
gs-3921	490	16	cultural	cultural	ADJ
gs-3921	490	17	research	research	NOUN
gs-3921	490	18	ethics	ethic	NOUN
gs-3921	490	19	,	,	PUNCT
gs-3921	490	20	and	and	CCONJ
gs-3921	490	21	integrate	integrate	VERB
gs-3921	490	22	local	local	ADJ
gs-3921	490	23	knowledge	knowledge	NOUN
gs-3921	490	24	systems	system	NOUN
gs-3921	490	25	.	.	PUNCT
gs-3921	491	1	moreover	moreover	ADV
gs-3921	491	2	,	,	PUNCT
gs-3921	491	3	the	the	DET
gs-3921	491	4	interplay	interplay	NOUN
gs-3921	491	5	between	between	ADP
gs-3921	491	6	genetic	genetic	ADJ
gs-3921	491	7	predisposition	predisposition	NOUN
gs-3921	491	8	and	and	CCONJ
gs-3921	491	9	environmental	environmental	ADJ
gs-3921	491	10	modulators	modulator	NOUN
gs-3921	491	11	such	such	ADJ
gs-3921	491	12	as	as	ADP
gs-3921	491	13	diet	diet	NOUN
gs-3921	491	14	,	,	PUNCT
gs-3921	491	15	concomitant	concomitant	ADJ
gs-3921	491	16	medications	medication	NOUN
gs-3921	491	17	,	,	PUNCT
gs-3921	491	18	comorbidities	comorbiditie	NOUN
gs-3921	491	19	,	,	PUNCT
gs-3921	491	20	and	and	CCONJ
gs-3921	491	21	lifestyle	lifestyle	NOUN
gs-3921	491	22	factors	factor	NOUN
gs-3921	491	23	must	must	AUX
gs-3921	491	24	be	be	AUX
gs-3921	491	25	accounted	account	VERB
gs-3921	491	26	for	for	ADP
gs-3921	491	27	to	to	PART
gs-3921	491	28	fully	fully	ADV
gs-3921	491	29	apprehend	apprehend	VERB
gs-3921	491	30	drug	drug	NOUN
gs-3921	491	31	response	response	NOUN
gs-3921	491	32	variability	variability	NOUN
gs-3921	491	33	.	.	PUNCT
gs-3921	492	1	for	for	ADP
gs-3921	492	2	instance	instance	NOUN
gs-3921	492	3	,	,	PUNCT
gs-3921	492	4	environmental	environmental	ADJ
gs-3921	492	5	inducers	inducer	NOUN
gs-3921	492	6	or	or	CCONJ
gs-3921	492	7	inhibitors	inhibitor	NOUN
gs-3921	492	8	of	of	ADP
gs-3921	492	9	cytochrome	cytochrome	ADJ
gs-3921	492	10	enzymes	enzyme	NOUN
gs-3921	492	11	can	can	AUX
gs-3921	492	12	modulate	modulate	VERB
gs-3921	492	13	the	the	DET
gs-3921	492	14	phenotypic	phenotypic	ADJ
gs-3921	492	15	expression	expression	NOUN
gs-3921	492	16	of	of	ADP
gs-3921	492	17	genetic	genetic	ADJ
gs-3921	492	18	variants	variant	NOUN
gs-3921	492	19	,	,	PUNCT
gs-3921	492	20	leading	lead	VERB
gs-3921	492	21	to	to	ADP
gs-3921	492	22	phenoconversion	phenoconversion	NOUN
gs-3921	492	23	and	and	CCONJ
gs-3921	492	24	unexpected	unexpected	ADJ
gs-3921	492	25	therapeutic	therapeutic	ADJ
gs-3921	492	26	outcomes	outcome	NOUN
gs-3921	492	27	.	.	PUNCT
gs-3921	493	1	incorporating	incorporate	VERB
gs-3921	493	2	such	such	ADJ
gs-3921	493	3	dynamic	dynamic	ADJ
gs-3921	493	4	gene	gene	NOUN
gs-3921	493	5	-	-	PUNCT
gs-3921	493	6	environment	environment	NOUN
gs-3921	493	7	interactions	interaction	NOUN
gs-3921	493	8	into	into	ADP
gs-3921	493	9	predictive	predictive	ADJ
gs-3921	493	10	models	model	NOUN
gs-3921	493	11	remains	remain	VERB
gs-3921	493	12	a	a	DET
gs-3921	493	13	methodological	methodological	ADJ
gs-3921	493	14	challenge	challenge	NOUN
gs-3921	493	15	but	but	CCONJ
gs-3921	493	16	represents	represent	VERB
gs-3921	493	17	an	an	DET
gs-3921	493	18	essential	essential	ADJ
gs-3921	493	19	frontier	frontier	NOUN
gs-3921	493	20	for	for	ADP
gs-3921	493	21	precision	precision	NOUN
gs-3921	493	22	medicine	medicine	NOUN
gs-3921	493	23	.	.	PUNCT
gs-3921	494	1	georgian	georgian	ADJ
gs-3921	494	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	494	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	494	4	ტ.	ტ.	VERB
gs-3921	494	5	7	7	NUM
gs-3921	494	6	n	n	DET
gs-3921	494	7	3	3	NUM
gs-3921	494	8	,	,	PUNCT
gs-3921	494	9	2025	2025	NUM
gs-3921	494	10	246	246	NUM
gs-3921	494	11	the	the	DET
gs-3921	494	12	role	role	NOUN
gs-3921	494	13	of	of	ADP
gs-3921	494	14	epigenetic	epigenetic	ADJ
gs-3921	494	15	regulation	regulation	NOUN
gs-3921	494	16	introduces	introduce	VERB
gs-3921	494	17	additional	additional	ADJ
gs-3921	494	18	layers	layer	NOUN
gs-3921	494	19	of	of	ADP
gs-3921	494	20	complexity	complexity	NOUN
gs-3921	494	21	.	.	PUNCT
gs-3921	495	1	epigenetic	epigenetic	ADJ
gs-3921	495	2	mechanisms	mechanism	NOUN
gs-3921	495	3	such	such	ADJ
gs-3921	495	4	as	as	ADP
gs-3921	495	5	dna	dna	PROPN
gs-3921	495	6	methylation	methylation	NOUN
gs-3921	495	7	,	,	PUNCT
gs-3921	495	8	histone	histone	NOUN
gs-3921	495	9	modifications	modification	NOUN
gs-3921	495	10	,	,	PUNCT
gs-3921	495	11	and	and	CCONJ
gs-3921	495	12	non	non	ADJ
gs-3921	495	13	-	-	ADJ
gs-3921	495	14	coding	code	VERB
gs-3921	495	15	rna	rna	NOUN
gs-3921	495	16	influence	influence	NOUN
gs-3921	495	17	gene	gene	NOUN
gs-3921	495	18	expression	expression	NOUN
gs-3921	495	19	profiles	profile	NOUN
gs-3921	495	20	relevant	relevant	ADJ
gs-3921	495	21	to	to	ADP
gs-3921	495	22	drug	drug	NOUN
gs-3921	495	23	metabolism	metabolism	NOUN
gs-3921	495	24	and	and	CCONJ
gs-3921	495	25	immune	immune	ADJ
gs-3921	495	26	responses	response	NOUN
gs-3921	495	27	.	.	PUNCT
gs-3921	496	1	importantly	importantly	ADV
gs-3921	496	2	,	,	PUNCT
gs-3921	496	3	these	these	DET
gs-3921	496	4	modifications	modification	NOUN
gs-3921	496	5	are	be	AUX
gs-3921	496	6	reversible	reversible	ADJ
gs-3921	496	7	and	and	CCONJ
gs-3921	496	8	responsive	responsive	ADJ
gs-3921	496	9	to	to	ADP
gs-3921	496	10	environmental	environmental	ADJ
gs-3921	496	11	cues	cue	NOUN
gs-3921	496	12	,	,	PUNCT
gs-3921	496	13	suggesting	suggest	VERB
gs-3921	496	14	potential	potential	ADJ
gs-3921	496	15	targets	target	NOUN
gs-3921	496	16	for	for	ADP
gs-3921	496	17	therapeutic	therapeutic	ADJ
gs-3921	496	18	modulation	modulation	NOUN
gs-3921	496	19	to	to	PART
gs-3921	496	20	mitigate	mitigate	VERB
gs-3921	496	21	adverse	adverse	ADJ
gs-3921	496	22	drug	drug	NOUN
gs-3921	496	23	reactions	reaction	NOUN
gs-3921	496	24	.	.	PUNCT
gs-3921	497	1	however	however	ADV
gs-3921	497	2	,	,	PUNCT
gs-3921	497	3	the	the	DET
gs-3921	497	4	clinical	clinical	ADJ
gs-3921	497	5	translation	translation	NOUN
gs-3921	497	6	of	of	ADP
gs-3921	497	7	epigenomic	epigenomic	ADJ
gs-3921	497	8	data	datum	NOUN
gs-3921	497	9	in	in	ADP
gs-3921	497	10	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	497	11	is	be	AUX
gs-3921	497	12	nascent	nascent	ADJ
gs-3921	497	13	,	,	PUNCT
gs-3921	497	14	demanding	demand	VERB
gs-3921	497	15	robust	robust	ADJ
gs-3921	497	16	longitudinal	longitudinal	ADJ
gs-3921	497	17	studies	study	NOUN
gs-3921	497	18	and	and	CCONJ
gs-3921	497	19	validation	validation	NOUN
gs-3921	497	20	frameworks	framework	NOUN
gs-3921	497	21	.	.	PUNCT
gs-3921	498	1	an	an	DET
gs-3921	498	2	underexplored	underexplored	ADJ
gs-3921	498	3	but	but	CCONJ
gs-3921	498	4	critical	critical	ADJ
gs-3921	498	5	domain	domain	NOUN
gs-3921	498	6	is	be	AUX
gs-3921	498	7	the	the	DET
gs-3921	498	8	influence	influence	NOUN
gs-3921	498	9	of	of	ADP
gs-3921	498	10	the	the	DET
gs-3921	498	11	microbiome	microbiome	NOUN
gs-3921	498	12	on	on	ADP
gs-3921	498	13	drug	drug	NOUN
gs-3921	498	14	metabolism	metabolism	NOUN
gs-3921	498	15	and	and	CCONJ
gs-3921	498	16	toxicity	toxicity	NOUN
gs-3921	498	17	.	.	PUNCT
gs-3921	499	1	the	the	DET
gs-3921	499	2	human	human	ADJ
gs-3921	499	3	gut	gut	NOUN
gs-3921	499	4	microbiota	microbiota	NOUN
gs-3921	499	5	expresses	express	VERB
gs-3921	499	6	enzymatic	enzymatic	ADJ
gs-3921	499	7	activities	activity	NOUN
gs-3921	499	8	capable	capable	ADJ
gs-3921	499	9	of	of	ADP
gs-3921	499	10	biotransforming	biotransforme	VERB
gs-3921	499	11	drugs	drug	NOUN
gs-3921	499	12	,	,	PUNCT
gs-3921	499	13	altering	alter	VERB
gs-3921	499	14	their	their	PRON
gs-3921	499	15	bioavailability	bioavailability	NOUN
gs-3921	499	16	,	,	PUNCT
gs-3921	499	17	efficacy	efficacy	NOUN
gs-3921	499	18	,	,	PUNCT
gs-3921	499	19	and	and	CCONJ
gs-3921	499	20	adverse	adverse	ADJ
gs-3921	499	21	effect	effect	NOUN
gs-3921	499	22	profiles	profile	NOUN
gs-3921	499	23	.	.	PUNCT
gs-3921	500	1	interindividual	interindividual	ADJ
gs-3921	500	2	variation	variation	NOUN
gs-3921	500	3	in	in	ADP
gs-3921	500	4	microbiome	microbiome	ADJ
gs-3921	500	5	composition	composition	NOUN
gs-3921	500	6	contributes	contribute	VERB
gs-3921	500	7	to	to	ADP
gs-3921	500	8	differential	differential	VERB
gs-3921	500	9	drug	drug	NOUN
gs-3921	500	10	response	response	NOUN
gs-3921	500	11	and	and	CCONJ
gs-3921	500	12	may	may	AUX
gs-3921	500	13	interact	interact	VERB
gs-3921	500	14	synergistically	synergistically	ADV
gs-3921	500	15	or	or	CCONJ
gs-3921	500	16	antagonistically	antagonistically	ADV
gs-3921	500	17	with	with	ADP
gs-3921	500	18	host	host	NOUN
gs-3921	500	19	genetic	genetic	ADJ
gs-3921	500	20	factors	factor	NOUN
gs-3921	500	21	.	.	PUNCT
gs-3921	501	1	integrating	integrate	VERB
gs-3921	501	2	microbiome	microbiome	NOUN
gs-3921	501	3	profiling	profiling	NOUN
gs-3921	501	4	with	with	ADP
gs-3921	501	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	501	6	analyses	analysis	NOUN
gs-3921	501	7	could	could	AUX
gs-3921	501	8	refine	refine	VERB
gs-3921	501	9	risk	risk	NOUN
gs-3921	501	10	stratification	stratification	NOUN
gs-3921	501	11	and	and	CCONJ
gs-3921	501	12	inform	inform	VERB
gs-3921	501	13	novel	novel	ADJ
gs-3921	501	14	therapeutic	therapeutic	ADJ
gs-3921	501	15	interventions	intervention	NOUN
gs-3921	501	16	.	.	PUNCT
gs-3921	502	1	the	the	DET
gs-3921	502	2	patient	patient	NOUN
gs-3921	502	3	-	-	PUNCT
gs-3921	502	4	centered	center	VERB
gs-3921	502	5	care	care	NOUN
gs-3921	502	6	paradigm	paradigm	NOUN
gs-3921	502	7	emerges	emerge	VERB
gs-3921	502	8	as	as	ADP
gs-3921	502	9	a	a	DET
gs-3921	502	10	keystone	keystone	NOUN
gs-3921	502	11	for	for	ADP
gs-3921	502	12	operationalizing	operationalize	VERB
gs-3921	502	13	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	502	14	in	in	ADP
gs-3921	502	15	clinical	clinical	ADJ
gs-3921	502	16	settings	setting	NOUN
gs-3921	502	17	.	.	PUNCT
gs-3921	503	1	this	this	DET
gs-3921	503	2	model	model	NOUN
gs-3921	503	3	emphasizes	emphasize	VERB
gs-3921	503	4	shared	shared	ADJ
gs-3921	503	5	decision	decision	NOUN
gs-3921	503	6	-	-	PUNCT
gs-3921	503	7	making	making	NOUN
gs-3921	503	8	,	,	PUNCT
gs-3921	503	9	tailored	tailor	VERB
gs-3921	503	10	communication	communication	NOUN
gs-3921	503	11	,	,	PUNCT
gs-3921	503	12	and	and	CCONJ
gs-3921	503	13	holistic	holistic	ADJ
gs-3921	503	14	consideration	consideration	NOUN
gs-3921	503	15	of	of	ADP
gs-3921	503	16	patient	patient	ADJ
gs-3921	503	17	values	value	NOUN
gs-3921	503	18	,	,	PUNCT
gs-3921	503	19	preferences	preference	NOUN
gs-3921	503	20	,	,	PUNCT
gs-3921	503	21	and	and	CCONJ
gs-3921	503	22	psychosocial	psychosocial	ADJ
gs-3921	503	23	context	context	NOUN
gs-3921	503	24	.	.	PUNCT
gs-3921	504	1	incorporation	incorporation	NOUN
gs-3921	504	2	of	of	ADP
gs-3921	504	3	genetic	genetic	ADJ
gs-3921	504	4	risk	risk	NOUN
gs-3921	504	5	information	information	NOUN
gs-3921	504	6	into	into	ADP
gs-3921	504	7	these	these	DET
gs-3921	504	8	discussions	discussion	NOUN
gs-3921	504	9	must	must	AUX
gs-3921	504	10	be	be	AUX
gs-3921	504	11	undertaken	undertake	VERB
gs-3921	504	12	with	with	ADP
gs-3921	504	13	sensitivity	sensitivity	NOUN
gs-3921	504	14	to	to	PART
gs-3921	504	15	avoid	avoid	VERB
gs-3921	504	16	generating	generate	VERB
gs-3921	504	17	anxiety	anxiety	NOUN
gs-3921	504	18	or	or	CCONJ
gs-3921	504	19	fatalistic	fatalistic	ADJ
gs-3921	504	20	attitudes	attitude	NOUN
gs-3921	504	21	.	.	PUNCT
gs-3921	505	1	empowering	empower	VERB
gs-3921	505	2	patients	patient	NOUN
gs-3921	505	3	through	through	ADP
gs-3921	505	4	education	education	NOUN
gs-3921	505	5	and	and	CCONJ
gs-3921	505	6	supportive	supportive	ADJ
gs-3921	505	7	counseling	counseling	NOUN
gs-3921	505	8	fosters	foster	VERB
gs-3921	505	9	adherence	adherence	NOUN
gs-3921	505	10	,	,	PUNCT
gs-3921	505	11	trust	trust	NOUN
gs-3921	505	12	,	,	PUNCT
gs-3921	505	13	and	and	CCONJ
gs-3921	505	14	optimal	optimal	ADJ
gs-3921	505	15	therapeutic	therapeutic	ADJ
gs-3921	505	16	outcomes	outcome	NOUN
gs-3921	505	17	.	.	PUNCT
gs-3921	506	1	despite	despite	SCONJ
gs-3921	506	2	these	these	DET
gs-3921	506	3	promising	promising	ADJ
gs-3921	506	4	directions	direction	NOUN
gs-3921	506	5	,	,	PUNCT
gs-3921	506	6	clinical	clinical	ADJ
gs-3921	506	7	workflow	workflow	NOUN
gs-3921	506	8	integration	integration	NOUN
gs-3921	506	9	remains	remain	VERB
gs-3921	506	10	a	a	DET
gs-3921	506	11	formidable	formidable	ADJ
gs-3921	506	12	barrier	barrier	NOUN
gs-3921	506	13	.	.	PUNCT
gs-3921	507	1	the	the	DET
gs-3921	507	2	proliferation	proliferation	NOUN
gs-3921	507	3	of	of	ADP
gs-3921	507	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	507	5	data	datum	NOUN
gs-3921	507	6	necessitates	necessitate	VERB
gs-3921	507	7	efficient	efficient	ADJ
gs-3921	507	8	,	,	PUNCT
gs-3921	507	9	userfriendly	userfriendly	ADV
gs-3921	507	10	platforms	platform	NOUN
gs-3921	507	11	embedded	embed	VERB
gs-3921	507	12	within	within	ADP
gs-3921	507	13	electronic	electronic	ADJ
gs-3921	507	14	health	health	NOUN
gs-3921	507	15	records	record	NOUN
gs-3921	507	16	to	to	PART
gs-3921	507	17	provide	provide	VERB
gs-3921	507	18	real	real	ADJ
gs-3921	507	19	-	-	PUNCT
gs-3921	507	20	time	time	NOUN
gs-3921	507	21	,	,	PUNCT
gs-3921	507	22	context	context	NOUN
gs-3921	507	23	-	-	PUNCT
gs-3921	507	24	specific	specific	ADJ
gs-3921	507	25	recommendations	recommendation	NOUN
gs-3921	507	26	without	without	ADP
gs-3921	507	27	overwhelming	overwhelming	ADJ
gs-3921	507	28	clinicians	clinician	NOUN
gs-3921	507	29	.	.	PUNCT
gs-3921	508	1	interdisciplinary	interdisciplinary	ADJ
gs-3921	508	2	collaboration	collaboration	NOUN
gs-3921	508	3	involving	involve	VERB
gs-3921	508	4	clinicians	clinician	NOUN
gs-3921	508	5	,	,	PUNCT
gs-3921	508	6	geneticists	geneticist	NOUN
gs-3921	508	7	,	,	PUNCT
gs-3921	508	8	bioinformaticians	bioinformatician	NOUN
gs-3921	508	9	,	,	PUNCT
gs-3921	508	10	and	and	CCONJ
gs-3921	508	11	informaticians	informatician	NOUN
gs-3921	508	12	is	be	AUX
gs-3921	508	13	crucial	crucial	ADJ
gs-3921	508	14	to	to	PART
gs-3921	508	15	develop	develop	VERB
gs-3921	508	16	adaptive	adaptive	ADJ
gs-3921	508	17	clinical	clinical	ADJ
gs-3921	508	18	decision	decision	NOUN
gs-3921	508	19	support	support	NOUN
gs-3921	508	20	systems	system	NOUN
gs-3921	508	21	that	that	PRON
gs-3921	508	22	evolve	evolve	VERB
gs-3921	508	23	with	with	ADP
gs-3921	508	24	emerging	emerge	VERB
gs-3921	508	25	evidence	evidence	NOUN
gs-3921	508	26	and	and	CCONJ
gs-3921	508	27	user	user	NOUN
gs-3921	508	28	feedback	feedback	NOUN
gs-3921	508	29	.	.	PUNCT
gs-3921	509	1	health	health	NOUN
gs-3921	509	2	disparities	disparity	NOUN
gs-3921	509	3	present	present	VERB
gs-3921	509	4	a	a	DET
gs-3921	509	5	significant	significant	ADJ
gs-3921	509	6	ethical	ethical	ADJ
gs-3921	509	7	and	and	CCONJ
gs-3921	509	8	practical	practical	ADJ
gs-3921	509	9	challenge	challenge	NOUN
gs-3921	509	10	in	in	ADP
gs-3921	509	11	the	the	DET
gs-3921	509	12	deployment	deployment	NOUN
gs-3921	509	13	of	of	ADP
gs-3921	509	14	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	509	15	services	service	NOUN
gs-3921	509	16	.	.	PUNCT
gs-3921	510	1	socioeconomic	socioeconomic	ADJ
gs-3921	510	2	factors	factor	NOUN
gs-3921	510	3	,	,	PUNCT
gs-3921	510	4	geographic	geographic	ADJ
gs-3921	510	5	accessibility	accessibility	NOUN
gs-3921	510	6	,	,	PUNCT
gs-3921	510	7	and	and	CCONJ
gs-3921	510	8	healthcare	healthcare	NOUN
gs-3921	510	9	infrastructure	infrastructure	NOUN
gs-3921	510	10	disparities	disparity	NOUN
gs-3921	510	11	contribute	contribute	VERB
gs-3921	510	12	to	to	ADP
gs-3921	510	13	unequal	unequal	ADJ
gs-3921	510	14	access	access	NOUN
gs-3921	510	15	,	,	PUNCT
gs-3921	510	16	potentially	potentially	ADV
gs-3921	510	17	exacerbating	exacerbate	VERB
gs-3921	510	18	health	health	NOUN
gs-3921	510	19	inequities	inequity	NOUN
gs-3921	510	20	.	.	PUNCT
gs-3921	511	1	strategies	strategy	NOUN
gs-3921	511	2	to	to	PART
gs-3921	511	3	mitigate	mitigate	VERB
gs-3921	511	4	these	these	DET
gs-3921	511	5	issues	issue	NOUN
gs-3921	511	6	include	include	VERB
gs-3921	511	7	decentralized	decentralized	ADJ
gs-3921	511	8	testing	testing	NOUN
gs-3921	511	9	models	model	NOUN
gs-3921	511	10	,	,	PUNCT
gs-3921	511	11	telemedicine	telemedicine	NOUN
gs-3921	511	12	-	-	PUNCT
gs-3921	511	13	based	base	VERB
gs-3921	511	14	genetic	genetic	ADJ
gs-3921	511	15	counseling	counseling	NOUN
gs-3921	511	16	,	,	PUNCT
gs-3921	511	17	and	and	CCONJ
gs-3921	511	18	community	community	NOUN
gs-3921	511	19	-	-	PUNCT
gs-3921	511	20	engaged	engage	VERB
gs-3921	511	21	research	research	NOUN
gs-3921	511	22	initiatives	initiative	NOUN
gs-3921	511	23	that	that	PRON
gs-3921	511	24	prioritize	prioritize	VERB
gs-3921	511	25	inclusivity	inclusivity	NOUN
gs-3921	511	26	and	and	CCONJ
gs-3921	511	27	cultural	cultural	ADJ
gs-3921	511	28	competence	competence	NOUN
gs-3921	511	29	.	.	PUNCT
gs-3921	512	1	the	the	DET
gs-3921	512	2	regulatory	regulatory	ADJ
gs-3921	512	3	environment	environment	NOUN
gs-3921	512	4	is	be	AUX
gs-3921	512	5	evolving	evolve	VERB
gs-3921	512	6	to	to	PART
gs-3921	512	7	accommodate	accommodate	VERB
gs-3921	512	8	the	the	DET
gs-3921	512	9	complexities	complexity	NOUN
gs-3921	512	10	of	of	ADP
gs-3921	512	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	512	12	testing	testing	NOUN
gs-3921	512	13	and	and	CCONJ
gs-3921	512	14	personalized	personalized	ADJ
gs-3921	512	15	medicine	medicine	NOUN
gs-3921	512	16	.	.	PUNCT
gs-3921	513	1	regulatory	regulatory	ADJ
gs-3921	513	2	bodies	body	NOUN
gs-3921	513	3	must	must	AUX
gs-3921	513	4	balance	balance	VERB
gs-3921	513	5	innovation	innovation	NOUN
gs-3921	513	6	facilitation	facilitation	NOUN
gs-3921	513	7	with	with	ADP
gs-3921	513	8	rigorous	rigorous	ADJ
gs-3921	513	9	evaluation	evaluation	NOUN
gs-3921	513	10	of	of	ADP
gs-3921	513	11	test	test	NOUN
gs-3921	513	12	validity	validity	NOUN
gs-3921	513	13	,	,	PUNCT
gs-3921	513	14	clinical	clinical	ADJ
gs-3921	513	15	utility	utility	NOUN
gs-3921	513	16	,	,	PUNCT
gs-3921	513	17	and	and	CCONJ
gs-3921	513	18	costeffectiveness	costeffectiveness	NOUN
gs-3921	513	19	.	.	PUNCT
gs-3921	514	1	harmonization	harmonization	NOUN
gs-3921	514	2	of	of	ADP
gs-3921	514	3	standards	standard	NOUN
gs-3921	514	4	across	across	ADP
gs-3921	514	5	jurisdictions	jurisdiction	NOUN
gs-3921	514	6	can	can	AUX
gs-3921	514	7	streamline	streamline	VERB
gs-3921	514	8	clinical	clinical	ADJ
gs-3921	514	9	implementation	implementation	NOUN
gs-3921	514	10	and	and	CCONJ
gs-3921	514	11	ensure	ensure	VERB
gs-3921	514	12	consistent	consistent	ADJ
gs-3921	514	13	quality	quality	NOUN
gs-3921	514	14	.	.	PUNCT
gs-3921	515	1	additionally	additionally	ADV
gs-3921	515	2	,	,	PUNCT
gs-3921	515	3	clear	clear	ADJ
gs-3921	515	4	guidelines	guideline	NOUN
gs-3921	515	5	on	on	ADP
gs-3921	515	6	data	datum	NOUN
gs-3921	515	7	georgian	georgian	ADJ
gs-3921	515	8	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	515	9	მეცნიერები	მეცნიერები	NOUN
gs-3921	515	10	ტ.	ტ.	VERB
gs-3921	515	11	7	7	NUM
gs-3921	515	12	n	n	PRON
gs-3921	515	13	3	3	NUM
gs-3921	515	14	,	,	PUNCT
gs-3921	515	15	2025	2025	NUM
gs-3921	515	16	247	247	NUM
gs-3921	515	17	ownership	ownership	NOUN
gs-3921	515	18	,	,	PUNCT
gs-3921	515	19	privacy	privacy	NOUN
gs-3921	515	20	,	,	PUNCT
gs-3921	515	21	and	and	CCONJ
gs-3921	515	22	sharing	sharing	NOUN
gs-3921	515	23	are	be	AUX
gs-3921	515	24	paramount	paramount	ADJ
gs-3921	515	25	to	to	PART
gs-3921	515	26	protect	protect	VERB
gs-3921	515	27	patient	patient	ADJ
gs-3921	515	28	rights	right	NOUN
gs-3921	515	29	while	while	SCONJ
gs-3921	515	30	enabling	enable	VERB
gs-3921	515	31	research	research	NOUN
gs-3921	515	32	advancement	advancement	NOUN
gs-3921	515	33	.	.	PUNCT
gs-3921	516	1	on	on	ADP
gs-3921	516	2	the	the	DET
gs-3921	516	3	frontier	frontier	NOUN
gs-3921	516	4	of	of	ADP
gs-3921	516	5	technological	technological	ADJ
gs-3921	516	6	innovation	innovation	NOUN
gs-3921	516	7	,	,	PUNCT
gs-3921	516	8	the	the	DET
gs-3921	516	9	integration	integration	NOUN
gs-3921	516	10	of	of	ADP
gs-3921	516	11	artificial	artificial	ADJ
gs-3921	516	12	intelligence	intelligence	NOUN
gs-3921	516	13	and	and	CCONJ
gs-3921	516	14	machine	machine	NOUN
gs-3921	516	15	learning	learn	VERB
gs-3921	516	16	algorithms	algorithm	NOUN
gs-3921	516	17	with	with	ADP
gs-3921	516	18	multi	multi	ADJ
gs-3921	516	19	-	-	ADJ
gs-3921	516	20	omic	omic	ADJ
gs-3921	516	21	and	and	CCONJ
gs-3921	516	22	clinical	clinical	ADJ
gs-3921	516	23	datasets	dataset	NOUN
gs-3921	516	24	heralds	herald	VERB
gs-3921	516	25	unprecedented	unprecedented	ADJ
gs-3921	516	26	potential	potential	NOUN
gs-3921	516	27	for	for	ADP
gs-3921	516	28	predictive	predictive	ADJ
gs-3921	516	29	analytics	analytic	NOUN
gs-3921	516	30	.	.	PUNCT
gs-3921	517	1	these	these	DET
gs-3921	517	2	tools	tool	NOUN
gs-3921	517	3	can	can	AUX
gs-3921	517	4	uncover	uncover	VERB
gs-3921	517	5	latent	latent	NOUN
gs-3921	517	6	patterns	pattern	NOUN
gs-3921	517	7	,	,	PUNCT
gs-3921	517	8	identify	identify	VERB
gs-3921	517	9	novel	novel	ADJ
gs-3921	517	10	gene	gene	NOUN
gs-3921	517	11	-	-	PUNCT
gs-3921	517	12	drug	drug	NOUN
gs-3921	517	13	interactions	interaction	NOUN
gs-3921	517	14	,	,	PUNCT
gs-3921	517	15	and	and	CCONJ
gs-3921	517	16	generate	generate	VERB
gs-3921	517	17	personalized	personalized	ADJ
gs-3921	517	18	risk	risk	NOUN
gs-3921	517	19	profiles	profile	NOUN
gs-3921	517	20	that	that	PRON
gs-3921	517	21	inform	inform	VERB
gs-3921	517	22	clinical	clinical	ADJ
gs-3921	517	23	decisions	decision	NOUN
gs-3921	517	24	.	.	PUNCT
gs-3921	518	1	nevertheless	nevertheless	ADV
gs-3921	518	2	,	,	PUNCT
gs-3921	518	3	transparency	transparency	NOUN
gs-3921	518	4	,	,	PUNCT
gs-3921	518	5	explainability	explainability	NOUN
gs-3921	518	6	,	,	PUNCT
gs-3921	518	7	and	and	CCONJ
gs-3921	518	8	ethical	ethical	ADJ
gs-3921	518	9	use	use	NOUN
gs-3921	518	10	of	of	ADP
gs-3921	518	11	ai	ai	PROPN
gs-3921	518	12	models	model	NOUN
gs-3921	518	13	require	require	VERB
gs-3921	518	14	ongoing	ongoing	ADJ
gs-3921	518	15	scrutiny	scrutiny	NOUN
gs-3921	518	16	and	and	CCONJ
gs-3921	518	17	governance	governance	NOUN
gs-3921	518	18	to	to	PART
gs-3921	518	19	prevent	prevent	VERB
gs-3921	518	20	bias	bias	NOUN
gs-3921	518	21	and	and	CCONJ
gs-3921	518	22	ensure	ensure	VERB
gs-3921	518	23	equitable	equitable	ADJ
gs-3921	518	24	benefit	benefit	NOUN
gs-3921	518	25	.	.	PUNCT
gs-3921	519	1	real	real	ADJ
gs-3921	519	2	-	-	PUNCT
gs-3921	519	3	world	world	NOUN
gs-3921	519	4	evidence	evidence	NOUN
gs-3921	519	5	derived	derive	VERB
gs-3921	519	6	from	from	ADP
gs-3921	519	7	large	large	ADJ
gs-3921	519	8	-	-	PUNCT
gs-3921	519	9	scale	scale	NOUN
gs-3921	519	10	biobanks	biobank	NOUN
gs-3921	519	11	,	,	PUNCT
gs-3921	519	12	longitudinal	longitudinal	ADJ
gs-3921	519	13	cohorts	cohort	NOUN
gs-3921	519	14	,	,	PUNCT
gs-3921	519	15	and	and	CCONJ
gs-3921	519	16	electronic	electronic	ADJ
gs-3921	519	17	health	health	NOUN
gs-3921	519	18	records	record	NOUN
gs-3921	519	19	enriched	enrich	VERB
gs-3921	519	20	with	with	ADP
gs-3921	519	21	genetic	genetic	ADJ
gs-3921	519	22	data	datum	NOUN
gs-3921	519	23	offers	offer	VERB
gs-3921	519	24	invaluable	invaluable	ADJ
gs-3921	519	25	insights	insight	NOUN
gs-3921	519	26	into	into	ADP
gs-3921	519	27	longterm	longterm	ADJ
gs-3921	519	28	safety	safety	NOUN
gs-3921	519	29	and	and	CCONJ
gs-3921	519	30	effectiveness	effectiveness	NOUN
gs-3921	519	31	of	of	ADP
gs-3921	519	32	genotype	genotype	NOUN
gs-3921	519	33	-	-	PUNCT
gs-3921	519	34	guided	guide	VERB
gs-3921	519	35	therapies	therapy	NOUN
gs-3921	519	36	.	.	PUNCT
gs-3921	520	1	collaborative	collaborative	ADJ
gs-3921	520	2	consortia	consortium	NOUN
gs-3921	520	3	and	and	CCONJ
gs-3921	520	4	data	data	NOUN
gs-3921	520	5	-	-	PUNCT
gs-3921	520	6	sharing	share	VERB
gs-3921	520	7	initiatives	initiative	NOUN
gs-3921	520	8	accelerate	accelerate	VERB
gs-3921	520	9	knowledge	knowledge	NOUN
gs-3921	520	10	dissemination	dissemination	NOUN
gs-3921	520	11	but	but	CCONJ
gs-3921	520	12	must	must	AUX
gs-3921	520	13	navigate	navigate	VERB
gs-3921	520	14	complex	complex	ADJ
gs-3921	520	15	issues	issue	NOUN
gs-3921	520	16	related	relate	VERB
gs-3921	520	17	to	to	ADP
gs-3921	520	18	data	data	NOUN
gs-3921	520	19	privacy	privacy	NOUN
gs-3921	520	20	,	,	PUNCT
gs-3921	520	21	consent	consent	NOUN
gs-3921	520	22	,	,	PUNCT
gs-3921	520	23	and	and	CCONJ
gs-3921	520	24	international	international	ADJ
gs-3921	520	25	legal	legal	ADJ
gs-3921	520	26	frameworks	framework	NOUN
gs-3921	520	27	.	.	PUNCT
gs-3921	521	1	the	the	DET
gs-3921	521	2	economic	economic	ADJ
gs-3921	521	3	sustainability	sustainability	NOUN
gs-3921	521	4	of	of	ADP
gs-3921	521	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	521	6	is	be	AUX
gs-3921	521	7	contingent	contingent	ADJ
gs-3921	521	8	upon	upon	SCONJ
gs-3921	521	9	comprehensive	comprehensive	ADJ
gs-3921	521	10	cost	cost	NOUN
gs-3921	521	11	-	-	PUNCT
gs-3921	521	12	benefit	benefit	NOUN
gs-3921	521	13	analyses	analysis	NOUN
gs-3921	521	14	that	that	PRON
gs-3921	521	15	incorporate	incorporate	VERB
gs-3921	521	16	direct	direct	ADJ
gs-3921	521	17	and	and	CCONJ
gs-3921	521	18	indirect	indirect	ADJ
gs-3921	521	19	healthcare	healthcare	NOUN
gs-3921	521	20	costs	cost	NOUN
gs-3921	521	21	,	,	PUNCT
gs-3921	521	22	quality	quality	NOUN
gs-3921	521	23	of	of	ADP
gs-3921	521	24	life	life	NOUN
gs-3921	521	25	metrics	metric	NOUN
gs-3921	521	26	,	,	PUNCT
gs-3921	521	27	and	and	CCONJ
gs-3921	521	28	societal	societal	ADJ
gs-3921	521	29	productivity	productivity	NOUN
gs-3921	521	30	.	.	PUNCT
gs-3921	522	1	early	early	ADJ
gs-3921	522	2	investment	investment	NOUN
gs-3921	522	3	in	in	ADP
gs-3921	522	4	testing	test	VERB
gs-3921	522	5	infrastructure	infrastructure	NOUN
gs-3921	522	6	and	and	CCONJ
gs-3921	522	7	clinician	clinician	NOUN
gs-3921	522	8	training	training	NOUN
gs-3921	522	9	is	be	AUX
gs-3921	522	10	offset	offset	VERB
gs-3921	522	11	by	by	ADP
gs-3921	522	12	reductions	reduction	NOUN
gs-3921	522	13	in	in	ADP
gs-3921	522	14	preventable	preventable	ADJ
gs-3921	522	15	adverse	adverse	ADJ
gs-3921	522	16	drug	drug	NOUN
gs-3921	522	17	events	event	NOUN
gs-3921	522	18	,	,	PUNCT
gs-3921	522	19	hospitalizations	hospitalization	NOUN
gs-3921	522	20	,	,	PUNCT
gs-3921	522	21	and	and	CCONJ
gs-3921	522	22	ineffective	ineffective	ADJ
gs-3921	522	23	therapies	therapy	NOUN
gs-3921	522	24	.	.	PUNCT
gs-3921	523	1	innovative	innovative	ADJ
gs-3921	523	2	payment	payment	NOUN
gs-3921	523	3	models	model	NOUN
gs-3921	523	4	that	that	PRON
gs-3921	523	5	reward	reward	VERB
gs-3921	523	6	outcomes	outcome	NOUN
gs-3921	523	7	rather	rather	ADV
gs-3921	523	8	than	than	ADP
gs-3921	523	9	volume	volume	NOUN
gs-3921	523	10	may	may	AUX
gs-3921	523	11	incentivize	incentivize	VERB
gs-3921	523	12	adoption	adoption	NOUN
gs-3921	523	13	.	.	PUNCT
gs-3921	524	1	the	the	DET
gs-3921	524	2	comprehensive	comprehensive	ADJ
gs-3921	524	3	integration	integration	NOUN
gs-3921	524	4	of	of	ADP
gs-3921	524	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	524	6	within	within	ADP
gs-3921	524	7	patient	patient	NOUN
gs-3921	524	8	-	-	PUNCT
gs-3921	524	9	centered	center	VERB
gs-3921	524	10	care	care	NOUN
gs-3921	524	11	and	and	CCONJ
gs-3921	524	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	524	13	systems	system	NOUN
gs-3921	524	14	embodies	embody	VERB
gs-3921	524	15	a	a	DET
gs-3921	524	16	transformative	transformative	ADJ
gs-3921	524	17	approach	approach	NOUN
gs-3921	524	18	to	to	ADP
gs-3921	524	19	medicine	medicine	NOUN
gs-3921	524	20	that	that	PRON
gs-3921	524	21	transcends	transcend	VERB
gs-3921	524	22	traditional	traditional	ADJ
gs-3921	524	23	boundaries	boundary	NOUN
gs-3921	524	24	.	.	PUNCT
gs-3921	525	1	realizing	realize	VERB
gs-3921	525	2	this	this	DET
gs-3921	525	3	vision	vision	NOUN
gs-3921	525	4	demands	demand	VERB
gs-3921	525	5	holistic	holistic	ADJ
gs-3921	525	6	strategies	strategy	NOUN
gs-3921	525	7	addressing	address	VERB
gs-3921	525	8	scientific	scientific	ADJ
gs-3921	525	9	,	,	PUNCT
gs-3921	525	10	clinical	clinical	ADJ
gs-3921	525	11	,	,	PUNCT
gs-3921	525	12	technological	technological	ADJ
gs-3921	525	13	,	,	PUNCT
gs-3921	525	14	ethical	ethical	ADJ
gs-3921	525	15	,	,	PUNCT
gs-3921	525	16	and	and	CCONJ
gs-3921	525	17	socioeconomic	socioeconomic	ADJ
gs-3921	525	18	dimensions	dimension	NOUN
gs-3921	525	19	.	.	PUNCT
gs-3921	526	1	multidisciplinary	multidisciplinary	ADJ
gs-3921	526	2	collaboration	collaboration	NOUN
gs-3921	526	3	,	,	PUNCT
gs-3921	526	4	sustained	sustained	ADJ
gs-3921	526	5	investment	investment	NOUN
gs-3921	526	6	,	,	PUNCT
gs-3921	526	7	and	and	CCONJ
gs-3921	526	8	patient	patient	ADJ
gs-3921	526	9	empowerment	empowerment	NOUN
gs-3921	526	10	will	will	AUX
gs-3921	526	11	be	be	AUX
gs-3921	526	12	pivotal	pivotal	ADJ
gs-3921	526	13	in	in	ADP
gs-3921	526	14	navigating	navigate	VERB
gs-3921	526	15	the	the	DET
gs-3921	526	16	complexities	complexity	NOUN
gs-3921	526	17	and	and	CCONJ
gs-3921	526	18	actualizing	actualize	VERB
gs-3921	526	19	the	the	DET
gs-3921	526	20	promise	promise	NOUN
gs-3921	526	21	of	of	ADP
gs-3921	526	22	personalized	personalize	VERB
gs-3921	526	23	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	526	24	for	for	ADP
gs-3921	526	25	safer	safe	ADJ
gs-3921	526	26	and	and	CCONJ
gs-3921	526	27	more	more	ADV
gs-3921	526	28	effective	effective	ADJ
gs-3921	526	29	treatment	treatment	NOUN
gs-3921	526	30	paradigms	paradigm	NOUN
gs-3921	526	31	.	.	PUNCT
gs-3921	527	1	the	the	DET
gs-3921	527	2	trajectory	trajectory	NOUN
gs-3921	527	3	of	of	ADP
gs-3921	527	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	527	5	in	in	ADP
gs-3921	527	6	clinical	clinical	ADJ
gs-3921	527	7	medicine	medicine	NOUN
gs-3921	527	8	is	be	AUX
gs-3921	527	9	increasingly	increasingly	ADV
gs-3921	527	10	influenced	influence	VERB
gs-3921	527	11	by	by	ADP
gs-3921	527	12	advances	advance	NOUN
gs-3921	527	13	in	in	ADP
gs-3921	527	14	precision	precision	NOUN
gs-3921	527	15	health	health	NOUN
gs-3921	527	16	,	,	PUNCT
gs-3921	527	17	an	an	DET
gs-3921	527	18	emerging	emerge	VERB
gs-3921	527	19	framework	framework	NOUN
gs-3921	527	20	that	that	PRON
gs-3921	527	21	extends	extend	VERB
gs-3921	527	22	beyond	beyond	ADP
gs-3921	527	23	treatment	treatment	NOUN
gs-3921	527	24	optimization	optimization	NOUN
gs-3921	527	25	to	to	PART
gs-3921	527	26	encompass	encompass	VERB
gs-3921	527	27	disease	disease	NOUN
gs-3921	527	28	prevention	prevention	NOUN
gs-3921	527	29	,	,	PUNCT
gs-3921	527	30	early	early	ADJ
gs-3921	527	31	diagnosis	diagnosis	NOUN
gs-3921	527	32	,	,	PUNCT
gs-3921	527	33	and	and	CCONJ
gs-3921	527	34	health	health	NOUN
gs-3921	527	35	promotion	promotion	NOUN
gs-3921	527	36	tailored	tailor	VERB
gs-3921	527	37	to	to	ADP
gs-3921	527	38	individual	individual	ADJ
gs-3921	527	39	variability	variability	NOUN
gs-3921	527	40	.	.	PUNCT
gs-3921	528	1	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	528	2	insights	insight	NOUN
gs-3921	528	3	are	be	AUX
gs-3921	528	4	pivotal	pivotal	ADJ
gs-3921	528	5	in	in	ADP
gs-3921	528	6	this	this	DET
gs-3921	528	7	broader	broad	ADJ
gs-3921	528	8	context	context	NOUN
gs-3921	528	9	,	,	PUNCT
gs-3921	528	10	enabling	enable	VERB
gs-3921	528	11	proactive	proactive	ADJ
gs-3921	528	12	identification	identification	NOUN
gs-3921	528	13	of	of	ADP
gs-3921	528	14	individuals	individual	NOUN
gs-3921	528	15	at	at	ADP
gs-3921	528	16	elevated	elevated	ADJ
gs-3921	528	17	risk	risk	NOUN
gs-3921	528	18	for	for	ADP
gs-3921	528	19	drug	drug	NOUN
gs-3921	528	20	-	-	PUNCT
gs-3921	528	21	induced	induce	VERB
gs-3921	528	22	toxicities	toxicity	NOUN
gs-3921	528	23	and	and	CCONJ
gs-3921	528	24	facilitating	facilitate	VERB
gs-3921	528	25	preemptive	preemptive	ADJ
gs-3921	528	26	therapeutic	therapeutic	ADJ
gs-3921	528	27	adjustments	adjustment	NOUN
gs-3921	528	28	.	.	PUNCT
gs-3921	529	1	this	this	DET
gs-3921	529	2	paradigm	paradigm	NOUN
gs-3921	529	3	shift	shift	NOUN
gs-3921	529	4	challenges	challenge	VERB
gs-3921	529	5	healthcare	healthcare	NOUN
gs-3921	529	6	systems	system	NOUN
gs-3921	529	7	to	to	PART
gs-3921	529	8	transition	transition	VERB
gs-3921	529	9	from	from	ADP
gs-3921	529	10	reactive	reactive	NOUN
gs-3921	529	11	to	to	ADP
gs-3921	529	12	anticipatory	anticipatory	ADJ
gs-3921	529	13	care	care	NOUN
gs-3921	529	14	models	model	NOUN
gs-3921	529	15	,	,	PUNCT
gs-3921	529	16	leveraging	leverage	VERB
gs-3921	529	17	genetic	genetic	ADJ
gs-3921	529	18	data	datum	NOUN
gs-3921	529	19	alongside	alongside	ADP
gs-3921	529	20	clinical	clinical	ADJ
gs-3921	529	21	and	and	CCONJ
gs-3921	529	22	environmental	environmental	ADJ
gs-3921	529	23	risk	risk	NOUN
gs-3921	529	24	factors	factor	NOUN
gs-3921	529	25	.	.	PUNCT
gs-3921	530	1	a	a	DET
gs-3921	530	2	critical	critical	ADJ
gs-3921	530	3	component	component	NOUN
gs-3921	530	4	of	of	ADP
gs-3921	530	5	this	this	DET
gs-3921	530	6	transition	transition	NOUN
gs-3921	530	7	is	be	AUX
gs-3921	530	8	the	the	DET
gs-3921	530	9	enhancement	enhancement	NOUN
gs-3921	530	10	of	of	ADP
gs-3921	530	11	healthcare	healthcare	NOUN
gs-3921	530	12	provider	provider	NOUN
gs-3921	530	13	competencies	competency	NOUN
gs-3921	530	14	in	in	ADP
gs-3921	530	15	genomics	genomic	NOUN
gs-3921	530	16	and	and	CCONJ
gs-3921	530	17	personalized	personalized	ADJ
gs-3921	530	18	medicine	medicine	NOUN
gs-3921	530	19	.	.	PUNCT
gs-3921	531	1	the	the	DET
gs-3921	531	2	current	current	ADJ
gs-3921	531	3	educational	educational	ADJ
gs-3921	531	4	gap	gap	NOUN
gs-3921	531	5	among	among	ADP
gs-3921	531	6	clinicians	clinician	NOUN
gs-3921	531	7	represents	represent	VERB
gs-3921	531	8	a	a	DET
gs-3921	531	9	substantial	substantial	ADJ
gs-3921	531	10	bottleneck	bottleneck	NOUN
gs-3921	531	11	to	to	ADP
gs-3921	531	12	effective	effective	ADJ
gs-3921	531	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	531	14	integration	integration	NOUN
gs-3921	531	15	.	.	PUNCT
gs-3921	532	1	progressive	progressive	ADJ
gs-3921	532	2	curricular	curricular	ADJ
gs-3921	532	3	reforms	reform	NOUN
gs-3921	532	4	incorporating	incorporate	VERB
gs-3921	532	5	genomics	genomic	NOUN
gs-3921	532	6	literacy	literacy	NOUN
gs-3921	532	7	,	,	PUNCT
gs-3921	532	8	ethical	ethical	ADJ
gs-3921	532	9	considerations	consideration	NOUN
gs-3921	532	10	,	,	PUNCT
gs-3921	532	11	and	and	CCONJ
gs-3921	532	12	interpretation	interpretation	NOUN
gs-3921	532	13	of	of	ADP
gs-3921	532	14	complex	complex	ADJ
gs-3921	532	15	test	test	NOUN
gs-3921	532	16	results	result	NOUN
gs-3921	532	17	are	be	AUX
gs-3921	532	18	imperative	imperative	ADJ
gs-3921	532	19	in	in	ADP
gs-3921	532	20	undergraduate	undergraduate	NOUN
gs-3921	532	21	,	,	PUNCT
gs-3921	532	22	graduate	graduate	NOUN
gs-3921	532	23	,	,	PUNCT
gs-3921	532	24	and	and	CCONJ
gs-3921	532	25	continuing	continue	VERB
gs-3921	532	26	professional	professional	ADJ
gs-3921	532	27	education	education	NOUN
gs-3921	532	28	.	.	PUNCT
gs-3921	533	1	simulation	simulation	NOUN
gs-3921	533	2	-	-	PUNCT
gs-3921	533	3	based	base	VERB
gs-3921	533	4	learning	learning	NOUN
gs-3921	533	5	,	,	PUNCT
gs-3921	533	6	interprofessional	interprofessional	ADJ
gs-3921	533	7	workshops	workshop	NOUN
gs-3921	534	1	,	,	PUNCT
gs-3921	534	2	georgian	georgian	ADJ
gs-3921	534	3	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	534	4	მეცნიერები	მეცნიერები	NOUN
gs-3921	534	5	ტ.	ტ.	VERB
gs-3921	534	6	7	7	NUM
gs-3921	534	7	n	n	PRON
gs-3921	534	8	3	3	NUM
gs-3921	534	9	,	,	PUNCT
gs-3921	534	10	2025	2025	NUM
gs-3921	534	11	248	248	NUM
gs-3921	534	12	and	and	CCONJ
gs-3921	534	13	decision	decision	NOUN
gs-3921	534	14	-	-	PUNCT
gs-3921	534	15	making	make	VERB
gs-3921	534	16	case	case	NOUN
gs-3921	534	17	studies	study	NOUN
gs-3921	534	18	have	have	AUX
gs-3921	534	19	shown	show	VERB
gs-3921	534	20	promise	promise	NOUN
gs-3921	534	21	in	in	ADP
gs-3921	534	22	improving	improve	VERB
gs-3921	534	23	clinician	clinician	ADJ
gs-3921	534	24	preparedness	preparedness	NOUN
gs-3921	534	25	and	and	CCONJ
gs-3921	534	26	confidence	confidence	NOUN
gs-3921	534	27	.	.	PUNCT
gs-3921	535	1	the	the	DET
gs-3921	535	2	role	role	NOUN
gs-3921	535	3	of	of	ADP
gs-3921	535	4	clinical	clinical	ADJ
gs-3921	535	5	pharmacists	pharmacist	NOUN
gs-3921	535	6	has	have	AUX
gs-3921	535	7	expanded	expand	VERB
gs-3921	535	8	significantly	significantly	ADV
gs-3921	535	9	within	within	ADP
gs-3921	535	10	this	this	DET
gs-3921	535	11	paradigm	paradigm	NOUN
gs-3921	535	12	.	.	PUNCT
gs-3921	536	1	as	as	ADP
gs-3921	536	2	medication	medication	NOUN
gs-3921	536	3	experts	expert	NOUN
gs-3921	536	4	,	,	PUNCT
gs-3921	536	5	pharmacists	pharmacist	NOUN
gs-3921	536	6	are	be	AUX
gs-3921	536	7	uniquely	uniquely	ADV
gs-3921	536	8	positioned	positioned	ADJ
gs-3921	536	9	to	to	PART
gs-3921	536	10	interpret	interpret	VERB
gs-3921	536	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	536	12	data	datum	NOUN
gs-3921	536	13	,	,	PUNCT
gs-3921	536	14	manage	manage	VERB
gs-3921	536	15	polypharmacy	polypharmacy	NOUN
gs-3921	536	16	,	,	PUNCT
gs-3921	536	17	and	and	CCONJ
gs-3921	536	18	liaise	liaise	VERB
gs-3921	536	19	with	with	ADP
gs-3921	536	20	multidisciplinary	multidisciplinary	ADJ
gs-3921	536	21	teams	team	NOUN
gs-3921	536	22	to	to	PART
gs-3921	536	23	tailor	tailor	NOUN
gs-3921	536	24	therapy	therapy	NOUN
gs-3921	536	25	.	.	PUNCT
gs-3921	537	1	integration	integration	NOUN
gs-3921	537	2	of	of	ADP
gs-3921	537	3	pharmacists	pharmacist	NOUN
gs-3921	537	4	into	into	ADP
gs-3921	537	5	genetic	genetic	ADJ
gs-3921	537	6	testing	testing	NOUN
gs-3921	537	7	workflows	workflow	NOUN
gs-3921	537	8	and	and	CCONJ
gs-3921	537	9	medication	medication	NOUN
gs-3921	537	10	management	management	NOUN
gs-3921	537	11	programs	program	NOUN
gs-3921	537	12	enhances	enhance	VERB
gs-3921	537	13	patient	patient	ADJ
gs-3921	537	14	safety	safety	NOUN
gs-3921	537	15	and	and	CCONJ
gs-3921	537	16	fosters	foster	VERB
gs-3921	537	17	effective	effective	ADJ
gs-3921	537	18	implementation	implementation	NOUN
gs-3921	537	19	.	.	PUNCT
gs-3921	538	1	moreover	moreover	ADV
gs-3921	538	2	,	,	PUNCT
gs-3921	538	3	pharmacists	pharmacist	NOUN
gs-3921	538	4	’	'	PUNCT
gs-3921	538	5	involvement	involvement	NOUN
gs-3921	538	6	in	in	ADP
gs-3921	538	7	patient	patient	ADJ
gs-3921	538	8	education	education	NOUN
gs-3921	538	9	facilitates	facilitate	VERB
gs-3921	538	10	informed	inform	VERB
gs-3921	538	11	consent	consent	NOUN
gs-3921	538	12	and	and	CCONJ
gs-3921	538	13	shared	share	VERB
gs-3921	538	14	decision	decision	NOUN
gs-3921	538	15	-	-	PUNCT
gs-3921	538	16	making	making	NOUN
gs-3921	538	17	,	,	PUNCT
gs-3921	538	18	addressing	address	VERB
gs-3921	538	19	patient	patient	ADJ
gs-3921	538	20	concerns	concern	NOUN
gs-3921	538	21	and	and	CCONJ
gs-3921	538	22	promoting	promote	VERB
gs-3921	538	23	adherence	adherence	NOUN
gs-3921	538	24	.	.	PUNCT
gs-3921	539	1	from	from	ADP
gs-3921	539	2	a	a	DET
gs-3921	539	3	research	research	NOUN
gs-3921	539	4	perspective	perspective	NOUN
gs-3921	539	5	,	,	PUNCT
gs-3921	539	6	the	the	DET
gs-3921	539	7	integration	integration	NOUN
gs-3921	539	8	of	of	ADP
gs-3921	539	9	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	539	10	with	with	ADP
gs-3921	539	11	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	539	12	and	and	CCONJ
gs-3921	539	13	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	539	14	is	be	AUX
gs-3921	539	15	evolving	evolve	VERB
gs-3921	539	16	toward	toward	ADP
gs-3921	539	17	a	a	DET
gs-3921	539	18	holistic	holistic	ADJ
gs-3921	539	19	systems	system	NOUN
gs-3921	539	20	biology	biology	NOUN
gs-3921	539	21	approach	approach	NOUN
gs-3921	539	22	.	.	PUNCT
gs-3921	540	1	network	network	NOUN
gs-3921	540	2	pharmacology	pharmacology	NOUN
gs-3921	540	3	models	model	NOUN
gs-3921	540	4	consider	consider	VERB
gs-3921	540	5	drug	drug	NOUN
gs-3921	540	6	-	-	PUNCT
gs-3921	540	7	target	target	NOUN
gs-3921	540	8	interactions	interaction	NOUN
gs-3921	540	9	within	within	ADP
gs-3921	540	10	complex	complex	ADJ
gs-3921	540	11	biological	biological	ADJ
gs-3921	540	12	pathways	pathway	NOUN
gs-3921	540	13	,	,	PUNCT
gs-3921	540	14	accounting	account	VERB
gs-3921	540	15	for	for	ADP
gs-3921	540	16	genetic	genetic	ADJ
gs-3921	540	17	variants	variant	NOUN
gs-3921	540	18	,	,	PUNCT
gs-3921	540	19	epigenetic	epigenetic	ADJ
gs-3921	540	20	factors	factor	NOUN
gs-3921	540	21	,	,	PUNCT
gs-3921	540	22	and	and	CCONJ
gs-3921	540	23	compensatory	compensatory	ADJ
gs-3921	540	24	mechanisms	mechanism	NOUN
gs-3921	540	25	.	.	PUNCT
gs-3921	541	1	such	such	ADJ
gs-3921	541	2	models	model	NOUN
gs-3921	541	3	aid	aid	VERB
gs-3921	541	4	in	in	ADP
gs-3921	541	5	elucidating	elucidating	NOUN
gs-3921	541	6	mechanisms	mechanism	NOUN
gs-3921	541	7	underlying	underlie	VERB
gs-3921	541	8	idiosyncratic	idiosyncratic	ADJ
gs-3921	541	9	adverse	adverse	ADJ
gs-3921	541	10	drug	drug	NOUN
gs-3921	541	11	reactions	reaction	NOUN
gs-3921	541	12	,	,	PUNCT
gs-3921	541	13	which	which	PRON
gs-3921	541	14	often	often	ADV
gs-3921	541	15	evade	evade	VERB
gs-3921	541	16	detection	detection	NOUN
gs-3921	541	17	in	in	ADP
gs-3921	541	18	traditional	traditional	ADJ
gs-3921	541	19	clinical	clinical	ADJ
gs-3921	541	20	trials	trial	NOUN
gs-3921	541	21	.	.	PUNCT
gs-3921	542	1	this	this	DET
gs-3921	542	2	comprehensive	comprehensive	ADJ
gs-3921	542	3	understanding	understanding	NOUN
gs-3921	542	4	can	can	AUX
gs-3921	542	5	inform	inform	VERB
gs-3921	542	6	the	the	DET
gs-3921	542	7	design	design	NOUN
gs-3921	542	8	of	of	ADP
gs-3921	542	9	safer	safe	ADJ
gs-3921	542	10	drugs	drug	NOUN
gs-3921	542	11	and	and	CCONJ
gs-3921	542	12	targeted	target	VERB
gs-3921	542	13	monitoring	monitoring	NOUN
gs-3921	542	14	strategies	strategy	NOUN
gs-3921	542	15	.	.	PUNCT
gs-3921	543	1	the	the	DET
gs-3921	543	2	emergence	emergence	NOUN
gs-3921	543	3	of	of	ADP
gs-3921	543	4	big	big	ADJ
gs-3921	543	5	data	datum	NOUN
gs-3921	543	6	analytics	analytic	NOUN
gs-3921	543	7	and	and	CCONJ
gs-3921	543	8	machine	machine	NOUN
gs-3921	543	9	learning	learning	NOUN
gs-3921	543	10	enables	enable	VERB
gs-3921	543	11	the	the	DET
gs-3921	543	12	handling	handling	NOUN
gs-3921	543	13	of	of	ADP
gs-3921	543	14	vast	vast	ADJ
gs-3921	543	15	,	,	PUNCT
gs-3921	543	16	multidimensional	multidimensional	ADJ
gs-3921	543	17	datasets	dataset	NOUN
gs-3921	543	18	that	that	PRON
gs-3921	543	19	characterize	characterize	VERB
gs-3921	543	20	modern	modern	ADJ
gs-3921	543	21	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	543	22	research	research	NOUN
gs-3921	543	23	.	.	PUNCT
gs-3921	544	1	these	these	DET
gs-3921	544	2	technologies	technology	NOUN
gs-3921	544	3	facilitate	facilitate	VERB
gs-3921	544	4	the	the	DET
gs-3921	544	5	identification	identification	NOUN
gs-3921	544	6	of	of	ADP
gs-3921	544	7	novel	novel	ADJ
gs-3921	544	8	genetic	genetic	ADJ
gs-3921	544	9	variants	variant	NOUN
gs-3921	544	10	and	and	CCONJ
gs-3921	544	11	rare	rare	ADJ
gs-3921	544	12	adverse	adverse	ADJ
gs-3921	544	13	event	event	NOUN
gs-3921	544	14	predictors	predictor	NOUN
gs-3921	544	15	,	,	PUNCT
gs-3921	544	16	potentially	potentially	ADV
gs-3921	544	17	unearthing	unearth	VERB
gs-3921	544	18	previously	previously	ADV
gs-3921	544	19	unrecognized	unrecognize	VERB
gs-3921	544	20	gene	gene	NOUN
gs-3921	544	21	-	-	PUNCT
gs-3921	544	22	drug	drug	NOUN
gs-3921	544	23	interactions	interaction	NOUN
gs-3921	544	24	.	.	PUNCT
gs-3921	545	1	nevertheless	nevertheless	ADV
gs-3921	545	2	,	,	PUNCT
gs-3921	545	3	the	the	DET
gs-3921	545	4	interpretability	interpretability	NOUN
gs-3921	545	5	of	of	ADP
gs-3921	545	6	complex	complex	ADJ
gs-3921	545	7	models	model	NOUN
gs-3921	545	8	remains	remain	VERB
gs-3921	545	9	a	a	DET
gs-3921	545	10	challenge	challenge	NOUN
gs-3921	545	11	,	,	PUNCT
gs-3921	545	12	necessitating	necessitate	VERB
gs-3921	545	13	transparent	transparent	ADJ
gs-3921	545	14	algorithm	algorithm	NOUN
gs-3921	545	15	development	development	NOUN
gs-3921	545	16	and	and	CCONJ
gs-3921	545	17	validation	validation	NOUN
gs-3921	545	18	in	in	ADP
gs-3921	545	19	diverse	diverse	ADJ
gs-3921	545	20	clinical	clinical	ADJ
gs-3921	545	21	cohorts	cohort	NOUN
gs-3921	545	22	.	.	PUNCT
gs-3921	546	1	in	in	ADP
gs-3921	546	2	addressing	address	VERB
gs-3921	546	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	546	4	disparities	disparity	NOUN
gs-3921	546	5	,	,	PUNCT
gs-3921	546	6	it	it	PRON
gs-3921	546	7	is	be	AUX
gs-3921	546	8	essential	essential	ADJ
gs-3921	546	9	to	to	PART
gs-3921	546	10	recognize	recognize	VERB
gs-3921	546	11	the	the	DET
gs-3921	546	12	influence	influence	NOUN
gs-3921	546	13	of	of	ADP
gs-3921	546	14	social	social	ADJ
gs-3921	546	15	determinants	determinant	NOUN
gs-3921	546	16	of	of	ADP
gs-3921	546	17	health	health	NOUN
gs-3921	546	18	on	on	ADP
gs-3921	546	19	access	access	NOUN
gs-3921	546	20	to	to	ADP
gs-3921	546	21	genetic	genetic	ADJ
gs-3921	546	22	services	service	NOUN
gs-3921	546	23	and	and	CCONJ
gs-3921	546	24	medication	medication	NOUN
gs-3921	546	25	safety	safety	NOUN
gs-3921	546	26	outcomes	outcome	NOUN
gs-3921	546	27	.	.	PUNCT
gs-3921	547	1	factors	factor	NOUN
gs-3921	547	2	such	such	ADJ
gs-3921	547	3	as	as	ADP
gs-3921	547	4	socioeconomic	socioeconomic	ADJ
gs-3921	547	5	status	status	NOUN
gs-3921	547	6	,	,	PUNCT
gs-3921	547	7	geographic	geographic	ADJ
gs-3921	547	8	location	location	NOUN
gs-3921	547	9	,	,	PUNCT
gs-3921	547	10	education	education	NOUN
gs-3921	547	11	level	level	NOUN
gs-3921	547	12	,	,	PUNCT
gs-3921	547	13	and	and	CCONJ
gs-3921	547	14	healthcare	healthcare	NOUN
gs-3921	547	15	access	access	NOUN
gs-3921	547	16	can	can	AUX
gs-3921	547	17	modulate	modulate	VERB
gs-3921	547	18	both	both	DET
gs-3921	547	19	exposure	exposure	NOUN
gs-3921	547	20	to	to	ADP
gs-3921	547	21	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	547	22	testing	testing	NOUN
gs-3921	547	23	and	and	CCONJ
gs-3921	547	24	medication	medication	NOUN
gs-3921	547	25	adherence	adherence	NOUN
gs-3921	547	26	.	.	PUNCT
gs-3921	548	1	tailored	tailor	VERB
gs-3921	548	2	outreach	outreach	NOUN
gs-3921	548	3	programs	program	NOUN
gs-3921	548	4	and	and	CCONJ
gs-3921	548	5	policy	policy	NOUN
gs-3921	548	6	interventions	intervention	NOUN
gs-3921	548	7	are	be	AUX
gs-3921	548	8	required	require	VERB
gs-3921	548	9	to	to	PART
gs-3921	548	10	ensure	ensure	VERB
gs-3921	548	11	equitable	equitable	ADJ
gs-3921	548	12	distribution	distribution	NOUN
gs-3921	548	13	of	of	ADP
gs-3921	548	14	the	the	DET
gs-3921	548	15	benefits	benefit	NOUN
gs-3921	548	16	of	of	ADP
gs-3921	548	17	pharmacogenomic	pharmacogenomic	ADJ
gs-3921	548	18	advances	advance	NOUN
gs-3921	548	19	.	.	PUNCT
gs-3921	549	1	the	the	DET
gs-3921	549	2	ethical	ethical	ADJ
gs-3921	549	3	landscape	landscape	NOUN
gs-3921	549	4	of	of	ADP
gs-3921	549	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	549	6	continues	continue	VERB
gs-3921	549	7	to	to	PART
gs-3921	549	8	evolve	evolve	VERB
gs-3921	549	9	with	with	ADP
gs-3921	549	10	the	the	DET
gs-3921	549	11	expanding	expand	VERB
gs-3921	549	12	scope	scope	NOUN
gs-3921	549	13	of	of	ADP
gs-3921	549	14	genetic	genetic	ADJ
gs-3921	549	15	testing	testing	NOUN
gs-3921	549	16	.	.	PUNCT
gs-3921	550	1	issues	issue	NOUN
gs-3921	550	2	surrounding	surround	VERB
gs-3921	550	3	incidental	incidental	ADJ
gs-3921	550	4	findings	finding	NOUN
gs-3921	550	5	,	,	PUNCT
gs-3921	550	6	such	such	ADJ
gs-3921	550	7	as	as	ADP
gs-3921	550	8	the	the	DET
gs-3921	550	9	discovery	discovery	NOUN
gs-3921	550	10	of	of	ADP
gs-3921	550	11	predispositions	predisposition	NOUN
gs-3921	550	12	to	to	ADP
gs-3921	550	13	unrelated	unrelated	ADJ
gs-3921	550	14	diseases	disease	NOUN
gs-3921	550	15	during	during	ADP
gs-3921	550	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	550	17	screening	screening	NOUN
gs-3921	550	18	,	,	PUNCT
gs-3921	550	19	raise	raise	VERB
gs-3921	550	20	complex	complex	ADJ
gs-3921	550	21	questions	question	NOUN
gs-3921	550	22	regarding	regard	VERB
gs-3921	550	23	disclosure	disclosure	NOUN
gs-3921	550	24	obligations	obligation	NOUN
gs-3921	550	25	,	,	PUNCT
gs-3921	550	26	patient	patient	ADJ
gs-3921	550	27	autonomy	autonomy	NOUN
gs-3921	550	28	,	,	PUNCT
gs-3921	550	29	and	and	CCONJ
gs-3921	550	30	psychological	psychological	ADJ
gs-3921	550	31	impact	impact	NOUN
gs-3921	550	32	.	.	PUNCT
gs-3921	551	1	frameworks	framework	NOUN
gs-3921	551	2	for	for	ADP
gs-3921	551	3	managing	manage	VERB
gs-3921	551	4	such	such	ADJ
gs-3921	551	5	findings	finding	NOUN
gs-3921	551	6	are	be	AUX
gs-3921	551	7	being	be	AUX
gs-3921	551	8	developed	develop	VERB
gs-3921	551	9	,	,	PUNCT
gs-3921	551	10	emphasizing	emphasize	VERB
gs-3921	551	11	the	the	DET
gs-3921	551	12	necessity	necessity	NOUN
gs-3921	551	13	for	for	ADP
gs-3921	551	14	comprehensive	comprehensive	ADJ
gs-3921	551	15	pre	pre	ADJ
gs-3921	551	16	-	-	ADJ
gs-3921	551	17	test	test	ADJ
gs-3921	551	18	counseling	counseling	NOUN
gs-3921	551	19	and	and	CCONJ
gs-3921	551	20	post	post	ADJ
gs-3921	551	21	-	-	ADJ
gs-3921	551	22	test	test	ADJ
gs-3921	551	23	support	support	NOUN
gs-3921	551	24	.	.	PUNCT
gs-3921	552	1	data	datum	NOUN
gs-3921	552	2	privacy	privacy	NOUN
gs-3921	552	3	and	and	CCONJ
gs-3921	552	4	security	security	NOUN
gs-3921	552	5	constitute	constitute	VERB
gs-3921	552	6	paramount	paramount	ADJ
gs-3921	552	7	concerns	concern	NOUN
gs-3921	552	8	as	as	SCONJ
gs-3921	552	9	genetic	genetic	ADJ
gs-3921	552	10	information	information	NOUN
gs-3921	552	11	becomes	becomes	AUX
gs-3921	552	12	increasingly	increasingly	ADV
gs-3921	552	13	integrated	integrate	VERB
gs-3921	552	14	into	into	ADP
gs-3921	552	15	health	health	NOUN
gs-3921	552	16	systems	system	NOUN
gs-3921	552	17	.	.	PUNCT
gs-3921	553	1	cybersecurity	cybersecurity	NOUN
gs-3921	553	2	threats	threat	NOUN
gs-3921	553	3	,	,	PUNCT
gs-3921	553	4	unauthorized	unauthorized	ADJ
gs-3921	553	5	data	datum	NOUN
gs-3921	553	6	sharing	sharing	NOUN
gs-3921	553	7	,	,	PUNCT
gs-3921	553	8	and	and	CCONJ
gs-3921	553	9	potential	potential	ADJ
gs-3921	553	10	misuse	misuse	NOUN
gs-3921	553	11	of	of	ADP
gs-3921	553	12	genetic	genetic	ADJ
gs-3921	553	13	data	datum	NOUN
gs-3921	553	14	necessitate	necessitate	ADJ
gs-3921	553	15	robust	robust	ADJ
gs-3921	553	16	technical	technical	ADJ
gs-3921	553	17	safeguards	safeguard	NOUN
gs-3921	553	18	,	,	PUNCT
gs-3921	553	19	policy	policy	NOUN
gs-3921	553	20	regulations	regulation	NOUN
gs-3921	553	21	,	,	PUNCT
gs-3921	553	22	and	and	CCONJ
gs-3921	553	23	patient	patient	ADJ
gs-3921	553	24	education	education	NOUN
gs-3921	553	25	.	.	PUNCT
gs-3921	554	1	the	the	DET
gs-3921	554	2	advent	advent	NOUN
gs-3921	554	3	of	of	ADP
gs-3921	554	4	blockchain	blockchain	PROPN
gs-3921	554	5	and	and	CCONJ
gs-3921	554	6	other	other	ADJ
gs-3921	554	7	decentralized	decentralize	VERB
gs-3921	554	8	georgian	georgian	ADJ
gs-3921	554	9	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	554	10	მეცნიერები	მეცნიერები	NOUN
gs-3921	554	11	ტ.	ტ.	VERB
gs-3921	554	12	7	7	NUM
gs-3921	554	13	n	n	PRON
gs-3921	554	14	3	3	NUM
gs-3921	554	15	,	,	PUNCT
gs-3921	554	16	2025	2025	NUM
gs-3921	554	17	249	249	NUM
gs-3921	554	18	technologies	technology	NOUN
gs-3921	554	19	offers	offer	VERB
gs-3921	554	20	innovative	innovative	ADJ
gs-3921	554	21	solutions	solution	NOUN
gs-3921	554	22	for	for	ADP
gs-3921	554	23	secure	secure	ADJ
gs-3921	554	24	,	,	PUNCT
gs-3921	554	25	patient	patient	NOUN
gs-3921	554	26	-	-	PUNCT
gs-3921	554	27	controlled	control	VERB
gs-3921	554	28	data	datum	NOUN
gs-3921	554	29	sharing	sharing	NOUN
gs-3921	554	30	,	,	PUNCT
gs-3921	554	31	but	but	CCONJ
gs-3921	554	32	implementation	implementation	NOUN
gs-3921	554	33	challenges	challenge	NOUN
gs-3921	554	34	and	and	CCONJ
gs-3921	554	35	regulatory	regulatory	ADJ
gs-3921	554	36	acceptance	acceptance	NOUN
gs-3921	554	37	remain	remain	VERB
gs-3921	554	38	ongoing	ongoing	ADJ
gs-3921	554	39	issues	issue	NOUN
gs-3921	554	40	.	.	PUNCT
gs-3921	555	1	the	the	DET
gs-3921	555	2	expanding	expand	VERB
gs-3921	555	3	availability	availability	NOUN
gs-3921	555	4	of	of	ADP
gs-3921	555	5	direct	direct	ADJ
gs-3921	555	6	-	-	PUNCT
gs-3921	555	7	to	to	ADP
gs-3921	555	8	-	-	PUNCT
gs-3921	555	9	consumer	consumer	NOUN
gs-3921	555	10	(	(	PUNCT
gs-3921	555	11	dtc	dtc	PROPN
gs-3921	555	12	)	)	PUNCT
gs-3921	555	13	genetic	genetic	ADJ
gs-3921	555	14	testing	testing	NOUN
gs-3921	555	15	poses	pose	VERB
gs-3921	555	16	additional	additional	ADJ
gs-3921	555	17	challenges	challenge	NOUN
gs-3921	555	18	and	and	CCONJ
gs-3921	555	19	opportunities	opportunity	NOUN
gs-3921	555	20	.	.	PUNCT
gs-3921	556	1	while	while	SCONJ
gs-3921	556	2	increasing	increase	VERB
gs-3921	556	3	public	public	ADJ
gs-3921	556	4	awareness	awareness	NOUN
gs-3921	556	5	and	and	CCONJ
gs-3921	556	6	engagement	engagement	NOUN
gs-3921	556	7	with	with	ADP
gs-3921	556	8	genetics	genetic	NOUN
gs-3921	556	9	,	,	PUNCT
gs-3921	556	10	dtc	dtc	NOUN
gs-3921	556	11	testing	testing	NOUN
gs-3921	556	12	often	often	ADV
gs-3921	556	13	lacks	lack	VERB
gs-3921	556	14	clinical	clinical	ADJ
gs-3921	556	15	validation	validation	NOUN
gs-3921	556	16	,	,	PUNCT
gs-3921	556	17	comprehensive	comprehensive	ADJ
gs-3921	556	18	interpretation	interpretation	NOUN
gs-3921	556	19	,	,	PUNCT
gs-3921	556	20	and	and	CCONJ
gs-3921	556	21	integration	integration	NOUN
gs-3921	556	22	into	into	ADP
gs-3921	556	23	healthcare	healthcare	PROPN
gs-3921	556	24	.	.	PUNCT
gs-3921	557	1	the	the	DET
gs-3921	557	2	potential	potential	NOUN
gs-3921	557	3	for	for	ADP
gs-3921	557	4	misinterpretation	misinterpretation	NOUN
gs-3921	557	5	and	and	CCONJ
gs-3921	557	6	inappropriate	inappropriate	ADJ
gs-3921	557	7	clinical	clinical	ADJ
gs-3921	557	8	decisions	decision	NOUN
gs-3921	557	9	underscores	underscore	VERB
gs-3921	557	10	the	the	DET
gs-3921	557	11	need	need	NOUN
gs-3921	557	12	for	for	ADP
gs-3921	557	13	regulatory	regulatory	ADJ
gs-3921	557	14	oversight	oversight	NOUN
gs-3921	557	15	,	,	PUNCT
gs-3921	557	16	clinician	clinician	NOUN
gs-3921	557	17	involvement	involvement	NOUN
gs-3921	557	18	,	,	PUNCT
gs-3921	557	19	and	and	CCONJ
gs-3921	557	20	public	public	ADJ
gs-3921	557	21	education	education	NOUN
gs-3921	557	22	to	to	PART
gs-3921	557	23	safeguard	safeguard	VERB
gs-3921	557	24	patient	patient	ADJ
gs-3921	557	25	welfare	welfare	NOUN
gs-3921	557	26	.	.	PUNCT
gs-3921	558	1	the	the	DET
gs-3921	558	2	field	field	NOUN
gs-3921	558	3	of	of	ADP
gs-3921	558	4	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	558	5	is	be	AUX
gs-3921	558	6	progressively	progressively	ADV
gs-3921	558	7	integrating	integrate	VERB
gs-3921	558	8	real	real	ADJ
gs-3921	558	9	-	-	PUNCT
gs-3921	558	10	world	world	NOUN
gs-3921	558	11	evidence	evidence	NOUN
gs-3921	558	12	(	(	PUNCT
gs-3921	558	13	rwe	rwe	PROPN
gs-3921	558	14	)	)	PUNCT
gs-3921	558	15	and	and	CCONJ
gs-3921	558	16	patient	patient	NOUN
gs-3921	558	17	-	-	PUNCT
gs-3921	558	18	generated	generate	VERB
gs-3921	558	19	data	datum	NOUN
gs-3921	558	20	to	to	PART
gs-3921	558	21	complement	complement	VERB
gs-3921	558	22	traditional	traditional	ADJ
gs-3921	558	23	surveillance	surveillance	NOUN
gs-3921	558	24	systems	system	NOUN
gs-3921	558	25	.	.	PUNCT
gs-3921	559	1	patientreported	patientreporte	VERB
gs-3921	559	2	outcomes	outcome	NOUN
gs-3921	559	3	,	,	PUNCT
gs-3921	559	4	wearable	wearable	ADJ
gs-3921	559	5	device	device	NOUN
gs-3921	559	6	data	datum	NOUN
gs-3921	559	7	,	,	PUNCT
gs-3921	559	8	and	and	CCONJ
gs-3921	559	9	mobile	mobile	ADJ
gs-3921	559	10	health	health	NOUN
gs-3921	559	11	applications	application	NOUN
gs-3921	559	12	enhance	enhance	VERB
gs-3921	559	13	the	the	DET
gs-3921	559	14	timeliness	timeliness	NOUN
gs-3921	559	15	and	and	CCONJ
gs-3921	559	16	sensitivity	sensitivity	NOUN
gs-3921	559	17	of	of	ADP
gs-3921	559	18	adverse	adverse	ADJ
gs-3921	559	19	event	event	NOUN
gs-3921	559	20	detection	detection	NOUN
gs-3921	559	21	,	,	PUNCT
gs-3921	559	22	particularly	particularly	ADV
gs-3921	559	23	in	in	ADP
gs-3921	559	24	genetically	genetically	ADV
gs-3921	559	25	susceptible	susceptible	ADJ
gs-3921	559	26	individuals	individual	NOUN
gs-3921	559	27	.	.	PUNCT
gs-3921	560	1	these	these	DET
gs-3921	560	2	patient	patient	NOUN
gs-3921	560	3	-	-	PUNCT
gs-3921	560	4	centered	center	VERB
gs-3921	560	5	approaches	approach	NOUN
gs-3921	560	6	democratize	democratize	VERB
gs-3921	560	7	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	560	8	but	but	CCONJ
gs-3921	560	9	require	require	VERB
gs-3921	560	10	standardized	standardized	ADJ
gs-3921	560	11	data	datum	NOUN
gs-3921	560	12	collection	collection	NOUN
gs-3921	560	13	protocols	protocol	NOUN
gs-3921	560	14	and	and	CCONJ
gs-3921	560	15	validation	validation	NOUN
gs-3921	560	16	methodologies	methodology	NOUN
gs-3921	560	17	.	.	PUNCT
gs-3921	561	1	global	global	ADJ
gs-3921	561	2	health	health	NOUN
gs-3921	561	3	perspectives	perspective	NOUN
gs-3921	561	4	reveal	reveal	VERB
gs-3921	561	5	significant	significant	ADJ
gs-3921	561	6	variability	variability	NOUN
gs-3921	561	7	in	in	ADP
gs-3921	561	8	the	the	DET
gs-3921	561	9	adoption	adoption	NOUN
gs-3921	561	10	of	of	ADP
gs-3921	561	11	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	561	12	,	,	PUNCT
gs-3921	561	13	influenced	influence	VERB
gs-3921	561	14	by	by	ADP
gs-3921	561	15	differences	difference	NOUN
gs-3921	561	16	in	in	ADP
gs-3921	561	17	healthcare	healthcare	PROPN
gs-3921	561	18	infrastructure	infrastructure	NOUN
gs-3921	561	19	,	,	PUNCT
gs-3921	561	20	genetic	genetic	ADJ
gs-3921	561	21	diversity	diversity	NOUN
gs-3921	561	22	,	,	PUNCT
gs-3921	561	23	regulatory	regulatory	ADJ
gs-3921	561	24	environments	environment	NOUN
gs-3921	561	25	,	,	PUNCT
gs-3921	561	26	and	and	CCONJ
gs-3921	561	27	economic	economic	ADJ
gs-3921	561	28	resources	resource	NOUN
gs-3921	561	29	.	.	PUNCT
gs-3921	562	1	lowand	lowand	ADJ
gs-3921	562	2	middle	middle	ADJ
gs-3921	562	3	-	-	PUNCT
gs-3921	562	4	income	income	NOUN
gs-3921	562	5	countries	country	NOUN
gs-3921	562	6	face	face	VERB
gs-3921	562	7	unique	unique	ADJ
gs-3921	562	8	challenges	challenge	NOUN
gs-3921	562	9	,	,	PUNCT
gs-3921	562	10	including	include	VERB
gs-3921	562	11	limited	limited	ADJ
gs-3921	562	12	laboratory	laboratory	NOUN
gs-3921	562	13	capacity	capacity	NOUN
gs-3921	562	14	,	,	PUNCT
gs-3921	562	15	scarcity	scarcity	NOUN
gs-3921	562	16	of	of	ADP
gs-3921	562	17	trained	train	VERB
gs-3921	562	18	personnel	personnel	NOUN
gs-3921	562	19	,	,	PUNCT
gs-3921	562	20	and	and	CCONJ
gs-3921	562	21	competing	compete	VERB
gs-3921	562	22	healthcare	healthcare	NOUN
gs-3921	562	23	priorities	priority	NOUN
gs-3921	562	24	.	.	PUNCT
gs-3921	563	1	international	international	ADJ
gs-3921	563	2	collaborations	collaboration	NOUN
gs-3921	563	3	and	and	CCONJ
gs-3921	563	4	capacity	capacity	NOUN
gs-3921	563	5	-	-	PUNCT
gs-3921	563	6	building	building	NOUN
gs-3921	563	7	initiatives	initiative	NOUN
gs-3921	563	8	focused	focus	VERB
gs-3921	563	9	on	on	ADP
gs-3921	563	10	technology	technology	NOUN
gs-3921	563	11	transfer	transfer	NOUN
gs-3921	563	12	,	,	PUNCT
gs-3921	563	13	education	education	NOUN
gs-3921	563	14	,	,	PUNCT
gs-3921	563	15	and	and	CCONJ
gs-3921	563	16	ethical	ethical	ADJ
gs-3921	563	17	frameworks	framework	NOUN
gs-3921	563	18	are	be	AUX
gs-3921	563	19	crucial	crucial	ADJ
gs-3921	563	20	to	to	ADP
gs-3921	563	21	closing	close	VERB
gs-3921	563	22	these	these	DET
gs-3921	563	23	gaps	gap	NOUN
gs-3921	563	24	.	.	PUNCT
gs-3921	564	1	the	the	DET
gs-3921	564	2	regulatory	regulatory	ADJ
gs-3921	564	3	environment	environment	NOUN
gs-3921	564	4	is	be	AUX
gs-3921	564	5	adapting	adapt	VERB
gs-3921	564	6	to	to	ADP
gs-3921	564	7	the	the	DET
gs-3921	564	8	complexities	complexity	NOUN
gs-3921	564	9	introduced	introduce	VERB
gs-3921	564	10	by	by	ADP
gs-3921	564	11	personalized	personalized	ADJ
gs-3921	564	12	medicine	medicine	NOUN
gs-3921	564	13	.	.	PUNCT
gs-3921	565	1	regulatory	regulatory	ADJ
gs-3921	565	2	agencies	agency	NOUN
gs-3921	565	3	are	be	AUX
gs-3921	565	4	developing	develop	VERB
gs-3921	565	5	guidelines	guideline	NOUN
gs-3921	565	6	for	for	ADP
gs-3921	565	7	the	the	DET
gs-3921	565	8	evaluation	evaluation	NOUN
gs-3921	565	9	and	and	CCONJ
gs-3921	565	10	approval	approval	NOUN
gs-3921	565	11	of	of	ADP
gs-3921	565	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	565	13	tests	test	NOUN
gs-3921	565	14	and	and	CCONJ
gs-3921	565	15	companion	companion	NOUN
gs-3921	565	16	diagnostics	diagnostic	NOUN
gs-3921	565	17	,	,	PUNCT
gs-3921	565	18	balancing	balance	VERB
gs-3921	565	19	innovation	innovation	NOUN
gs-3921	565	20	with	with	ADP
gs-3921	565	21	patient	patient	ADJ
gs-3921	565	22	safety	safety	NOUN
gs-3921	565	23	.	.	PUNCT
gs-3921	566	1	harmonization	harmonization	NOUN
gs-3921	566	2	efforts	effort	NOUN
gs-3921	566	3	aim	aim	VERB
gs-3921	566	4	to	to	PART
gs-3921	566	5	facilitate	facilitate	VERB
gs-3921	566	6	global	global	ADJ
gs-3921	566	7	consistency	consistency	NOUN
gs-3921	566	8	,	,	PUNCT
gs-3921	566	9	enabling	enable	VERB
gs-3921	566	10	more	more	ADV
gs-3921	566	11	rapid	rapid	ADJ
gs-3921	566	12	dissemination	dissemination	NOUN
gs-3921	566	13	and	and	CCONJ
gs-3921	566	14	adoption	adoption	NOUN
gs-3921	566	15	of	of	ADP
gs-3921	566	16	validated	validated	ADJ
gs-3921	566	17	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	566	18	tools	tool	NOUN
gs-3921	566	19	.	.	PUNCT
gs-3921	567	1	looking	look	VERB
gs-3921	567	2	forward	forward	ADV
gs-3921	567	3	,	,	PUNCT
gs-3921	567	4	the	the	DET
gs-3921	567	5	integration	integration	NOUN
gs-3921	567	6	of	of	ADP
gs-3921	567	7	multi	multi	ADJ
gs-3921	567	8	-	-	ADJ
gs-3921	567	9	omic	omic	ADJ
gs-3921	567	10	data	datum	NOUN
gs-3921	567	11	with	with	ADP
gs-3921	567	12	digital	digital	ADJ
gs-3921	567	13	health	health	NOUN
gs-3921	567	14	technologies	technology	NOUN
gs-3921	567	15	promises	promise	VERB
gs-3921	567	16	to	to	PART
gs-3921	567	17	refine	refine	VERB
gs-3921	567	18	personalized	personalized	ADJ
gs-3921	567	19	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	567	20	further	far	ADV
gs-3921	567	21	.	.	PUNCT
gs-3921	568	1	the	the	DET
gs-3921	568	2	convergence	convergence	NOUN
gs-3921	568	3	of	of	ADP
gs-3921	568	4	genomics	genomic	NOUN
gs-3921	568	5	,	,	PUNCT
gs-3921	568	6	proteomics	proteomic	NOUN
gs-3921	568	7	,	,	PUNCT
gs-3921	568	8	metabolomics	metabolomic	NOUN
gs-3921	568	9	,	,	PUNCT
gs-3921	568	10	and	and	CCONJ
gs-3921	568	11	microbiomics	microbiomic	NOUN
gs-3921	568	12	with	with	ADP
gs-3921	568	13	artificial	artificial	ADJ
gs-3921	568	14	intelligence	intelligence	NOUN
gs-3921	568	15	-	-	PUNCT
gs-3921	568	16	driven	drive	VERB
gs-3921	568	17	clinical	clinical	ADJ
gs-3921	568	18	decision	decision	NOUN
gs-3921	568	19	support	support	NOUN
gs-3921	568	20	platforms	platform	NOUN
gs-3921	568	21	offers	offer	VERB
gs-3921	568	22	unprecedented	unprecedented	ADJ
gs-3921	568	23	opportunities	opportunity	NOUN
gs-3921	568	24	to	to	PART
gs-3921	568	25	anticipate	anticipate	VERB
gs-3921	568	26	,	,	PUNCT
gs-3921	568	27	prevent	prevent	VERB
gs-3921	568	28	,	,	PUNCT
gs-3921	568	29	and	and	CCONJ
gs-3921	568	30	manage	manage	VERB
gs-3921	568	31	adverse	adverse	ADJ
gs-3921	568	32	drug	drug	NOUN
gs-3921	568	33	reactions	reaction	NOUN
gs-3921	568	34	at	at	ADP
gs-3921	568	35	the	the	DET
gs-3921	568	36	individual	individual	ADJ
gs-3921	568	37	level	level	NOUN
gs-3921	568	38	.	.	PUNCT
gs-3921	569	1	to	to	PART
gs-3921	569	2	capitalize	capitalize	VERB
gs-3921	569	3	on	on	ADP
gs-3921	569	4	these	these	DET
gs-3921	569	5	advances	advance	NOUN
gs-3921	569	6	,	,	PUNCT
gs-3921	569	7	healthcare	healthcare	NOUN
gs-3921	569	8	systems	system	NOUN
gs-3921	569	9	must	must	AUX
gs-3921	569	10	prioritize	prioritize	VERB
gs-3921	569	11	the	the	DET
gs-3921	569	12	development	development	NOUN
gs-3921	569	13	of	of	ADP
gs-3921	569	14	interoperable	interoperable	ADJ
gs-3921	569	15	data	datum	NOUN
gs-3921	569	16	infrastructures	infrastructure	NOUN
gs-3921	569	17	and	and	CCONJ
gs-3921	569	18	promote	promote	VERB
gs-3921	569	19	interdisciplinary	interdisciplinary	ADJ
gs-3921	569	20	collaboration	collaboration	NOUN
gs-3921	569	21	among	among	ADP
gs-3921	569	22	clinicians	clinician	NOUN
gs-3921	569	23	,	,	PUNCT
gs-3921	569	24	geneticists	geneticist	NOUN
gs-3921	569	25	,	,	PUNCT
gs-3921	569	26	data	datum	NOUN
gs-3921	569	27	scientists	scientist	NOUN
gs-3921	569	28	,	,	PUNCT
gs-3921	569	29	ethicists	ethicist	NOUN
gs-3921	569	30	,	,	PUNCT
gs-3921	569	31	and	and	CCONJ
gs-3921	569	32	policymakers	policymaker	NOUN
gs-3921	569	33	.	.	PUNCT
gs-3921	570	1	patient	patient	ADJ
gs-3921	570	2	engagement	engagement	NOUN
gs-3921	570	3	and	and	CCONJ
gs-3921	570	4	empowerment	empowerment	NOUN
gs-3921	570	5	remain	remain	VERB
gs-3921	570	6	central	central	ADJ
gs-3921	570	7	,	,	PUNCT
gs-3921	570	8	requiring	require	VERB
gs-3921	570	9	continuous	continuous	ADJ
gs-3921	570	10	efforts	effort	NOUN
gs-3921	570	11	to	to	PART
gs-3921	570	12	enhance	enhance	VERB
gs-3921	570	13	health	health	NOUN
gs-3921	570	14	literacy	literacy	NOUN
gs-3921	570	15	,	,	PUNCT
gs-3921	570	16	trust	trust	NOUN
gs-3921	570	17	,	,	PUNCT
gs-3921	570	18	and	and	CCONJ
gs-3921	570	19	shared	share	VERB
gs-3921	570	20	decision	decision	NOUN
gs-3921	570	21	-	-	PUNCT
gs-3921	570	22	making	making	NOUN
gs-3921	570	23	.	.	PUNCT
gs-3921	571	1	the	the	DET
gs-3921	571	2	future	future	NOUN
gs-3921	571	3	of	of	ADP
gs-3921	571	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	571	5	and	and	CCONJ
gs-3921	571	6	patient	patient	NOUN
gs-3921	571	7	-	-	PUNCT
gs-3921	571	8	centered	center	VERB
gs-3921	571	9	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	571	10	is	be	AUX
gs-3921	571	11	promising	promise	VERB
gs-3921	571	12	yet	yet	ADV
gs-3921	571	13	complex	complex	ADJ
gs-3921	571	14	.	.	PUNCT
gs-3921	572	1	the	the	DET
gs-3921	572	2	translation	translation	NOUN
gs-3921	572	3	of	of	ADP
gs-3921	572	4	scientific	scientific	ADJ
gs-3921	572	5	discoveries	discovery	NOUN
gs-3921	572	6	into	into	ADP
gs-3921	572	7	routine	routine	ADJ
gs-3921	572	8	clinical	clinical	ADJ
gs-3921	572	9	practice	practice	NOUN
gs-3921	572	10	necessitates	necessitate	VERB
gs-3921	572	11	multifaceted	multifaceted	ADJ
gs-3921	572	12	strategies	strategy	NOUN
gs-3921	572	13	addressing	address	VERB
gs-3921	572	14	technical	technical	ADJ
gs-3921	572	15	,	,	PUNCT
gs-3921	572	16	clinical	clinical	ADJ
gs-3921	572	17	,	,	PUNCT
gs-3921	572	18	ethical	ethical	ADJ
gs-3921	572	19	,	,	PUNCT
gs-3921	572	20	economic	economic	ADJ
gs-3921	572	21	,	,	PUNCT
gs-3921	572	22	and	and	CCONJ
gs-3921	572	23	social	social	ADJ
gs-3921	572	24	dimensions	dimension	NOUN
gs-3921	572	25	.	.	PUNCT
gs-3921	573	1	a	a	DET
gs-3921	573	2	concerted	concerted	ADJ
gs-3921	573	3	global	global	ADJ
gs-3921	573	4	effort	effort	NOUN
gs-3921	573	5	,	,	PUNCT
gs-3921	573	6	underpinned	underpin	VERB
gs-3921	573	7	by	by	ADP
gs-3921	573	8	robust	robust	ADJ
gs-3921	573	9	evidence	evidence	NOUN
gs-3921	573	10	and	and	CCONJ
gs-3921	573	11	ethical	ethical	ADJ
gs-3921	573	12	georgian	georgian	ADJ
gs-3921	573	13	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	573	14	მეცნიერები	მეცნიერები	NOUN
gs-3921	573	15	ტ.	ტ.	VERB
gs-3921	573	16	7	7	NUM
gs-3921	573	17	n	n	PRON
gs-3921	573	18	3	3	NUM
gs-3921	573	19	,	,	PUNCT
gs-3921	573	20	2025	2025	NUM
gs-3921	573	21	250	250	NUM
gs-3921	573	22	stewardship	stewardship	NOUN
gs-3921	573	23	,	,	PUNCT
gs-3921	573	24	is	be	AUX
gs-3921	573	25	essential	essential	ADJ
gs-3921	573	26	to	to	PART
gs-3921	573	27	realize	realize	VERB
gs-3921	573	28	the	the	DET
gs-3921	573	29	full	full	ADJ
gs-3921	573	30	potential	potential	NOUN
gs-3921	573	31	of	of	ADP
gs-3921	573	32	personalized	personalized	ADJ
gs-3921	573	33	medicine	medicine	NOUN
gs-3921	573	34	in	in	ADP
gs-3921	573	35	improving	improve	VERB
gs-3921	573	36	medication	medication	NOUN
gs-3921	573	37	safety	safety	NOUN
gs-3921	573	38	and	and	CCONJ
gs-3921	573	39	therapeutic	therapeutic	ADJ
gs-3921	573	40	efficacy	efficacy	NOUN
gs-3921	573	41	.	.	PUNCT
gs-3921	574	1	future	future	ADJ
gs-3921	574	2	prospects	prospect	NOUN
gs-3921	574	3	the	the	DET
gs-3921	574	4	future	future	NOUN
gs-3921	574	5	of	of	ADP
gs-3921	574	6	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	574	7	and	and	CCONJ
gs-3921	574	8	patient	patient	NOUN
gs-3921	574	9	-	-	PUNCT
gs-3921	574	10	centered	center	VERB
gs-3921	574	11	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	574	12	is	be	AUX
gs-3921	574	13	poised	poise	VERB
gs-3921	574	14	for	for	ADP
gs-3921	574	15	remarkable	remarkable	ADJ
gs-3921	574	16	transformation	transformation	NOUN
gs-3921	574	17	driven	drive	VERB
gs-3921	574	18	by	by	ADP
gs-3921	574	19	rapid	rapid	ADJ
gs-3921	574	20	technological	technological	ADJ
gs-3921	574	21	innovation	innovation	NOUN
gs-3921	574	22	,	,	PUNCT
gs-3921	574	23	expanding	expand	VERB
gs-3921	574	24	scientific	scientific	ADJ
gs-3921	574	25	understanding	understanding	NOUN
gs-3921	574	26	,	,	PUNCT
gs-3921	574	27	and	and	CCONJ
gs-3921	574	28	evolving	evolve	VERB
gs-3921	574	29	healthcare	healthcare	NOUN
gs-3921	574	30	paradigms	paradigm	VERB
gs-3921	574	31	.	.	PUNCT
gs-3921	575	1	the	the	DET
gs-3921	575	2	convergence	convergence	NOUN
gs-3921	575	3	of	of	ADP
gs-3921	575	4	genomics	genomic	NOUN
gs-3921	575	5	,	,	PUNCT
gs-3921	575	6	digital	digital	ADJ
gs-3921	575	7	health	health	NOUN
gs-3921	575	8	,	,	PUNCT
gs-3921	575	9	and	and	CCONJ
gs-3921	575	10	systems	system	NOUN
gs-3921	575	11	biology	biology	NOUN
gs-3921	575	12	promises	promise	VERB
gs-3921	575	13	to	to	PART
gs-3921	575	14	reshape	reshape	VERB
gs-3921	575	15	how	how	SCONJ
gs-3921	575	16	medication	medication	NOUN
gs-3921	575	17	-	-	PUNCT
gs-3921	575	18	induced	induce	VERB
gs-3921	575	19	adverse	adverse	ADJ
gs-3921	575	20	effects	effect	NOUN
gs-3921	575	21	and	and	CCONJ
gs-3921	575	22	toxicities	toxicity	NOUN
gs-3921	575	23	are	be	AUX
gs-3921	575	24	predicted	predict	VERB
gs-3921	575	25	,	,	PUNCT
gs-3921	575	26	prevented	prevent	VERB
gs-3921	575	27	,	,	PUNCT
gs-3921	575	28	and	and	CCONJ
gs-3921	575	29	managed	manage	VERB
gs-3921	575	30	,	,	PUNCT
gs-3921	575	31	ultimately	ultimately	ADV
gs-3921	575	32	enhancing	enhance	VERB
gs-3921	575	33	patient	patient	ADJ
gs-3921	575	34	safety	safety	NOUN
gs-3921	575	35	and	and	CCONJ
gs-3921	575	36	therapeutic	therapeutic	ADJ
gs-3921	575	37	efficacy	efficacy	NOUN
gs-3921	575	38	on	on	ADP
gs-3921	575	39	a	a	DET
gs-3921	575	40	global	global	ADJ
gs-3921	575	41	scale	scale	NOUN
gs-3921	575	42	.	.	PUNCT
gs-3921	576	1	one	one	NUM
gs-3921	576	2	of	of	ADP
gs-3921	576	3	the	the	DET
gs-3921	576	4	foremost	foremost	ADJ
gs-3921	576	5	future	future	ADJ
gs-3921	576	6	directions	direction	NOUN
gs-3921	576	7	is	be	AUX
gs-3921	576	8	the	the	DET
gs-3921	576	9	widespread	widespread	ADJ
gs-3921	576	10	adoption	adoption	NOUN
gs-3921	576	11	of	of	ADP
gs-3921	576	12	preemptive	preemptive	ADJ
gs-3921	576	13	,	,	PUNCT
gs-3921	576	14	comprehensive	comprehensive	ADJ
gs-3921	576	15	genomic	genomic	NOUN
gs-3921	576	16	profiling	profiling	NOUN
gs-3921	576	17	integrated	integrate	VERB
gs-3921	576	18	into	into	ADP
gs-3921	576	19	routine	routine	ADJ
gs-3921	576	20	healthcare	healthcare	NOUN
gs-3921	576	21	.	.	PUNCT
gs-3921	577	1	advances	advance	NOUN
gs-3921	577	2	in	in	ADP
gs-3921	577	3	nextgeneration	nextgeneration	NOUN
gs-3921	577	4	sequencing	sequencing	NOUN
gs-3921	577	5	and	and	CCONJ
gs-3921	577	6	decreasing	decrease	VERB
gs-3921	577	7	costs	cost	NOUN
gs-3921	577	8	will	will	AUX
gs-3921	577	9	facilitate	facilitate	VERB
gs-3921	577	10	broad	broad	ADJ
gs-3921	577	11	population	population	NOUN
gs-3921	577	12	-	-	PUNCT
gs-3921	577	13	level	level	NOUN
gs-3921	577	14	screening	screening	NOUN
gs-3921	577	15	,	,	PUNCT
gs-3921	577	16	enabling	enable	VERB
gs-3921	577	17	clinicians	clinician	NOUN
gs-3921	577	18	to	to	PART
gs-3921	577	19	access	access	VERB
gs-3921	577	20	an	an	DET
gs-3921	577	21	individual	individual	NOUN
gs-3921	577	22	’s	’s	PART
gs-3921	577	23	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	577	24	landscape	landscape	NOUN
gs-3921	577	25	early	early	ADV
gs-3921	577	26	in	in	ADP
gs-3921	577	27	life	life	NOUN
gs-3921	577	28	or	or	CCONJ
gs-3921	577	29	prior	prior	ADV
gs-3921	577	30	to	to	ADP
gs-3921	577	31	therapy	therapy	NOUN
gs-3921	577	32	initiation	initiation	NOUN
gs-3921	577	33	.	.	PUNCT
gs-3921	578	1	such	such	ADJ
gs-3921	578	2	data	data	NOUN
gs-3921	578	3	repositories	repository	NOUN
gs-3921	578	4	,	,	PUNCT
gs-3921	578	5	linked	link	VERB
gs-3921	578	6	longitudinally	longitudinally	ADV
gs-3921	578	7	to	to	ADP
gs-3921	578	8	clinical	clinical	ADJ
gs-3921	578	9	records	record	NOUN
gs-3921	578	10	,	,	PUNCT
gs-3921	578	11	will	will	AUX
gs-3921	578	12	support	support	VERB
gs-3921	578	13	dynamic	dynamic	ADJ
gs-3921	578	14	and	and	CCONJ
gs-3921	578	15	lifelong	lifelong	ADJ
gs-3921	578	16	medication	medication	NOUN
gs-3921	578	17	optimization	optimization	NOUN
gs-3921	578	18	,	,	PUNCT
gs-3921	578	19	minimizing	minimize	VERB
gs-3921	578	20	adverse	adverse	ADJ
gs-3921	578	21	drug	drug	NOUN
gs-3921	578	22	reactions	reaction	NOUN
gs-3921	578	23	and	and	CCONJ
gs-3921	578	24	enhancing	enhance	VERB
gs-3921	578	25	personalized	personalized	ADJ
gs-3921	578	26	care	care	NOUN
gs-3921	578	27	continuity	continuity	NOUN
gs-3921	578	28	.	.	PUNCT
gs-3921	579	1	the	the	DET
gs-3921	579	2	integration	integration	NOUN
gs-3921	579	3	of	of	ADP
gs-3921	579	4	multi	multi	ADJ
gs-3921	579	5	-	-	ADJ
gs-3921	579	6	omics	omics	ADJ
gs-3921	579	7	data	datum	NOUN
gs-3921	579	8	—	—	PUNCT
gs-3921	579	9	including	include	VERB
gs-3921	579	10	epigenomics	epigenomic	NOUN
gs-3921	579	11	,	,	PUNCT
gs-3921	579	12	transcriptomics	transcriptomic	NOUN
gs-3921	579	13	,	,	PUNCT
gs-3921	579	14	proteomics	proteomic	NOUN
gs-3921	579	15	,	,	PUNCT
gs-3921	579	16	and	and	CCONJ
gs-3921	579	17	metabolomics	metabolomic	NOUN
gs-3921	579	18	—	—	PUNCT
gs-3921	579	19	with	with	ADP
gs-3921	579	20	genomic	genomic	ADJ
gs-3921	579	21	information	information	NOUN
gs-3921	579	22	will	will	AUX
gs-3921	579	23	enrich	enrich	VERB
gs-3921	579	24	predictive	predictive	ADJ
gs-3921	579	25	models	model	NOUN
gs-3921	579	26	of	of	ADP
gs-3921	579	27	drug	drug	NOUN
gs-3921	579	28	response	response	NOUN
gs-3921	579	29	and	and	CCONJ
gs-3921	579	30	toxicity	toxicity	NOUN
gs-3921	579	31	.	.	PUNCT
gs-3921	580	1	systems	system	NOUN
gs-3921	580	2	pharmacology	pharmacology	NOUN
gs-3921	580	3	approaches	approach	VERB
gs-3921	580	4	leveraging	leverage	VERB
gs-3921	580	5	these	these	DET
gs-3921	580	6	complex	complex	ADJ
gs-3921	580	7	datasets	dataset	NOUN
gs-3921	580	8	will	will	AUX
gs-3921	580	9	elucidate	elucidate	VERB
gs-3921	580	10	intricate	intricate	ADJ
gs-3921	580	11	biological	biological	ADJ
gs-3921	580	12	networks	network	NOUN
gs-3921	580	13	and	and	CCONJ
gs-3921	580	14	pathways	pathway	NOUN
gs-3921	580	15	modulating	modulate	VERB
gs-3921	580	16	pharmacodynamics	pharmacodynamic	NOUN
gs-3921	580	17	and	and	CCONJ
gs-3921	580	18	pharmacokinetics	pharmacokinetic	NOUN
gs-3921	580	19	.	.	PUNCT
gs-3921	581	1	this	this	DET
gs-3921	581	2	holistic	holistic	ADJ
gs-3921	581	3	understanding	understanding	NOUN
gs-3921	581	4	will	will	AUX
gs-3921	581	5	drive	drive	VERB
gs-3921	581	6	the	the	DET
gs-3921	581	7	discovery	discovery	NOUN
gs-3921	581	8	of	of	ADP
gs-3921	581	9	novel	novel	ADJ
gs-3921	581	10	biomarkers	biomarker	NOUN
gs-3921	581	11	and	and	CCONJ
gs-3921	581	12	therapeutic	therapeutic	ADJ
gs-3921	581	13	targets	target	NOUN
gs-3921	581	14	,	,	PUNCT
gs-3921	581	15	paving	pave	VERB
gs-3921	581	16	the	the	DET
gs-3921	581	17	way	way	NOUN
gs-3921	581	18	for	for	ADP
gs-3921	581	19	next	next	ADJ
gs-3921	581	20	-	-	PUNCT
gs-3921	581	21	generation	generation	NOUN
gs-3921	581	22	precision	precision	NOUN
gs-3921	581	23	therapeutics	therapeutic	NOUN
gs-3921	581	24	tailored	tailor	VERB
gs-3921	581	25	to	to	ADP
gs-3921	581	26	multifactorial	multifactorial	ADJ
gs-3921	581	27	determinants	determinant	NOUN
gs-3921	581	28	of	of	ADP
gs-3921	581	29	drug	drug	NOUN
gs-3921	581	30	response	response	NOUN
gs-3921	581	31	.	.	PUNCT
gs-3921	582	1	emerging	emerge	VERB
gs-3921	582	2	artificial	artificial	ADJ
gs-3921	582	3	intelligence	intelligence	NOUN
gs-3921	582	4	(	(	PUNCT
gs-3921	582	5	ai	ai	NOUN
gs-3921	582	6	)	)	PUNCT
gs-3921	582	7	and	and	CCONJ
gs-3921	582	8	machine	machine	NOUN
gs-3921	582	9	learning	learning	NOUN
gs-3921	582	10	(	(	PUNCT
gs-3921	582	11	ml	ml	NOUN
gs-3921	582	12	)	)	PUNCT
gs-3921	582	13	technologies	technology	NOUN
gs-3921	582	14	will	will	AUX
gs-3921	582	15	revolutionize	revolutionize	VERB
gs-3921	582	16	data	data	NOUN
gs-3921	582	17	interpretation	interpretation	NOUN
gs-3921	582	18	,	,	PUNCT
gs-3921	582	19	clinical	clinical	ADJ
gs-3921	582	20	decision	decision	NOUN
gs-3921	582	21	support	support	NOUN
gs-3921	582	22	,	,	PUNCT
gs-3921	582	23	and	and	CCONJ
gs-3921	582	24	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	582	25	.	.	PUNCT
gs-3921	583	1	ai	ai	VERB
gs-3921	583	2	algorithms	algorithm	NOUN
gs-3921	583	3	trained	train	VERB
gs-3921	583	4	on	on	ADP
gs-3921	583	5	expansive	expansive	ADJ
gs-3921	583	6	,	,	PUNCT
gs-3921	583	7	diverse	diverse	ADJ
gs-3921	583	8	datasets	dataset	NOUN
gs-3921	583	9	will	will	AUX
gs-3921	583	10	identify	identify	VERB
gs-3921	583	11	subtle	subtle	ADJ
gs-3921	583	12	gene	gene	NOUN
gs-3921	583	13	-	-	PUNCT
gs-3921	583	14	drugenvironment	drugenvironment	NOUN
gs-3921	583	15	interactions	interaction	NOUN
gs-3921	583	16	and	and	CCONJ
gs-3921	583	17	real	real	ADJ
gs-3921	583	18	-	-	PUNCT
gs-3921	583	19	time	time	NOUN
gs-3921	583	20	adverse	adverse	ADJ
gs-3921	583	21	event	event	NOUN
gs-3921	583	22	signals	signal	NOUN
gs-3921	583	23	,	,	PUNCT
gs-3921	583	24	enabling	enable	VERB
gs-3921	583	25	proactive	proactive	ADJ
gs-3921	583	26	risk	risk	NOUN
gs-3921	583	27	mitigation	mitigation	NOUN
gs-3921	583	28	.	.	PUNCT
gs-3921	584	1	the	the	DET
gs-3921	584	2	development	development	NOUN
gs-3921	584	3	of	of	ADP
gs-3921	584	4	explainable	explainable	ADJ
gs-3921	584	5	ai	ai	NOUN
gs-3921	584	6	models	model	NOUN
gs-3921	584	7	will	will	AUX
gs-3921	584	8	facilitate	facilitate	VERB
gs-3921	584	9	clinician	clinician	NOUN
gs-3921	584	10	trust	trust	NOUN
gs-3921	584	11	and	and	CCONJ
gs-3921	584	12	adoption	adoption	NOUN
gs-3921	584	13	,	,	PUNCT
gs-3921	584	14	supporting	support	VERB
gs-3921	584	15	complex	complex	ADJ
gs-3921	584	16	,	,	PUNCT
gs-3921	584	17	data	datum	NOUN
gs-3921	584	18	-	-	PUNCT
gs-3921	584	19	driven	drive	VERB
gs-3921	584	20	therapeutic	therapeutic	ADJ
gs-3921	584	21	decisions	decision	NOUN
gs-3921	584	22	within	within	ADP
gs-3921	584	23	fast	fast	ADV
gs-3921	584	24	-	-	PUNCT
gs-3921	584	25	paced	pace	VERB
gs-3921	584	26	clinical	clinical	ADJ
gs-3921	584	27	environments	environment	NOUN
gs-3921	584	28	.	.	PUNCT
gs-3921	585	1	the	the	DET
gs-3921	585	2	growth	growth	NOUN
gs-3921	585	3	of	of	ADP
gs-3921	585	4	digital	digital	ADJ
gs-3921	585	5	health	health	NOUN
gs-3921	585	6	platforms	platform	NOUN
gs-3921	585	7	and	and	CCONJ
gs-3921	585	8	mobile	mobile	NOUN
gs-3921	585	9	technologies	technology	NOUN
gs-3921	585	10	will	will	AUX
gs-3921	585	11	empower	empower	VERB
gs-3921	585	12	patients	patient	NOUN
gs-3921	585	13	as	as	ADP
gs-3921	585	14	active	active	ADJ
gs-3921	585	15	participants	participant	NOUN
gs-3921	585	16	in	in	ADP
gs-3921	585	17	their	their	PRON
gs-3921	585	18	care	care	NOUN
gs-3921	585	19	.	.	PUNCT
gs-3921	586	1	wearable	wearable	ADJ
gs-3921	586	2	biosensors	biosensor	NOUN
gs-3921	586	3	and	and	CCONJ
gs-3921	586	4	smartphone	smartphone	NOUN
gs-3921	586	5	applications	application	NOUN
gs-3921	586	6	will	will	AUX
gs-3921	586	7	enable	enable	VERB
gs-3921	586	8	continuous	continuous	ADJ
gs-3921	586	9	monitoring	monitoring	NOUN
gs-3921	586	10	of	of	ADP
gs-3921	586	11	physiological	physiological	ADJ
gs-3921	586	12	and	and	CCONJ
gs-3921	586	13	biochemical	biochemical	ADJ
gs-3921	586	14	parameters	parameter	NOUN
gs-3921	586	15	indicative	indicative	ADJ
gs-3921	586	16	of	of	ADP
gs-3921	586	17	drug	drug	NOUN
gs-3921	586	18	toxicity	toxicity	NOUN
gs-3921	586	19	or	or	CCONJ
gs-3921	586	20	therapeutic	therapeutic	ADJ
gs-3921	586	21	efficacy	efficacy	NOUN
gs-3921	586	22	,	,	PUNCT
gs-3921	586	23	delivering	deliver	VERB
gs-3921	586	24	personalized	personalized	ADJ
gs-3921	586	25	alerts	alert	NOUN
gs-3921	586	26	and	and	CCONJ
gs-3921	586	27	enabling	enable	VERB
gs-3921	586	28	timely	timely	ADJ
gs-3921	586	29	clinical	clinical	ADJ
gs-3921	586	30	interventions	intervention	NOUN
gs-3921	586	31	.	.	PUNCT
gs-3921	587	1	integration	integration	NOUN
gs-3921	587	2	of	of	ADP
gs-3921	587	3	these	these	DET
gs-3921	587	4	patient	patient	NOUN
gs-3921	587	5	-	-	PUNCT
gs-3921	587	6	generated	generate	VERB
gs-3921	587	7	data	data	NOUN
gs-3921	587	8	streams	stream	NOUN
gs-3921	587	9	with	with	ADP
gs-3921	587	10	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	587	11	information	information	NOUN
gs-3921	587	12	will	will	AUX
gs-3921	587	13	support	support	VERB
gs-3921	587	14	truly	truly	ADV
gs-3921	587	15	individualized	individualized	ADJ
gs-3921	587	16	,	,	PUNCT
gs-3921	587	17	adaptive	adaptive	ADJ
gs-3921	587	18	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	587	19	.	.	PUNCT
gs-3921	588	1	addressing	address	VERB
gs-3921	588	2	existing	exist	VERB
gs-3921	588	3	disparities	disparity	NOUN
gs-3921	588	4	in	in	ADP
gs-3921	588	5	access	access	NOUN
gs-3921	588	6	to	to	ADP
gs-3921	588	7	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	588	8	testing	testing	NOUN
gs-3921	588	9	and	and	CCONJ
gs-3921	588	10	personalized	personalized	ADJ
gs-3921	588	11	care	care	NOUN
gs-3921	588	12	remains	remain	VERB
gs-3921	588	13	a	a	DET
gs-3921	588	14	critical	critical	ADJ
gs-3921	588	15	priority	priority	NOUN
gs-3921	588	16	.	.	PUNCT
gs-3921	589	1	future	future	ADJ
gs-3921	589	2	strategies	strategy	NOUN
gs-3921	589	3	must	must	AUX
gs-3921	589	4	emphasize	emphasize	VERB
gs-3921	589	5	health	health	NOUN
gs-3921	589	6	equity	equity	NOUN
gs-3921	589	7	through	through	ADP
gs-3921	589	8	georgian	georgian	ADJ
gs-3921	589	9	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	589	10	მეცნიერები	მეცნიერები	NOUN
gs-3921	589	11	ტ.	ტ.	VERB
gs-3921	589	12	7	7	NUM
gs-3921	589	13	n	n	DET
gs-3921	589	14	3	3	NUM
gs-3921	589	15	,	,	PUNCT
gs-3921	589	16	2025	2025	NUM
gs-3921	589	17	251	251	NUM
gs-3921	589	18	global	global	ADJ
gs-3921	589	19	capacity	capacity	NOUN
gs-3921	589	20	building	building	NOUN
gs-3921	589	21	,	,	PUNCT
gs-3921	589	22	telemedicine	telemedicine	NOUN
gs-3921	589	23	expansion	expansion	NOUN
gs-3921	589	24	,	,	PUNCT
gs-3921	589	25	and	and	CCONJ
gs-3921	589	26	culturally	culturally	ADV
gs-3921	589	27	competent	competent	ADJ
gs-3921	589	28	care	care	NOUN
gs-3921	589	29	models	model	NOUN
gs-3921	589	30	.	.	PUNCT
gs-3921	590	1	collaborative	collaborative	ADJ
gs-3921	590	2	international	international	ADJ
gs-3921	590	3	initiatives	initiative	NOUN
gs-3921	590	4	will	will	AUX
gs-3921	590	5	be	be	AUX
gs-3921	590	6	essential	essential	ADJ
gs-3921	590	7	to	to	PART
gs-3921	590	8	harmonize	harmonize	VERB
gs-3921	590	9	testing	testing	NOUN
gs-3921	590	10	standards	standard	NOUN
gs-3921	590	11	,	,	PUNCT
gs-3921	590	12	share	share	NOUN
gs-3921	590	13	data	datum	NOUN
gs-3921	590	14	securely	securely	ADV
gs-3921	590	15	,	,	PUNCT
gs-3921	590	16	and	and	CCONJ
gs-3921	590	17	disseminate	disseminate	VERB
gs-3921	590	18	best	good	ADJ
gs-3921	590	19	practices	practice	NOUN
gs-3921	590	20	across	across	ADP
gs-3921	590	21	diverse	diverse	ADJ
gs-3921	590	22	healthcare	healthcare	NOUN
gs-3921	590	23	settings	setting	NOUN
gs-3921	590	24	.	.	PUNCT
gs-3921	591	1	regulatory	regulatory	ADJ
gs-3921	591	2	frameworks	framework	NOUN
gs-3921	591	3	will	will	AUX
gs-3921	591	4	evolve	evolve	VERB
gs-3921	591	5	to	to	PART
gs-3921	591	6	accommodate	accommodate	VERB
gs-3921	591	7	the	the	DET
gs-3921	591	8	complexities	complexity	NOUN
gs-3921	591	9	of	of	ADP
gs-3921	591	10	integrated	integrate	VERB
gs-3921	591	11	,	,	PUNCT
gs-3921	591	12	data	data	NOUN
gs-3921	591	13	-	-	PUNCT
gs-3921	591	14	rich	rich	ADJ
gs-3921	591	15	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	591	16	applications	application	NOUN
gs-3921	591	17	.	.	PUNCT
gs-3921	592	1	the	the	DET
gs-3921	592	2	establishment	establishment	NOUN
gs-3921	592	3	of	of	ADP
gs-3921	592	4	adaptive	adaptive	ADJ
gs-3921	592	5	regulatory	regulatory	ADJ
gs-3921	592	6	pathways	pathway	NOUN
gs-3921	592	7	will	will	AUX
gs-3921	592	8	facilitate	facilitate	VERB
gs-3921	592	9	timely	timely	ADJ
gs-3921	592	10	approval	approval	NOUN
gs-3921	592	11	of	of	ADP
gs-3921	592	12	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	592	13	tests	test	NOUN
gs-3921	592	14	and	and	CCONJ
gs-3921	592	15	companion	companion	NOUN
gs-3921	592	16	diagnostics	diagnostic	NOUN
gs-3921	592	17	,	,	PUNCT
gs-3921	592	18	balancing	balance	VERB
gs-3921	592	19	innovation	innovation	NOUN
gs-3921	592	20	with	with	ADP
gs-3921	592	21	patient	patient	ADJ
gs-3921	592	22	safety	safety	NOUN
gs-3921	592	23	.	.	PUNCT
gs-3921	593	1	policies	policy	NOUN
gs-3921	593	2	ensuring	ensure	VERB
gs-3921	593	3	robust	robust	ADJ
gs-3921	593	4	genetic	genetic	ADJ
gs-3921	593	5	data	datum	NOUN
gs-3921	593	6	privacy	privacy	NOUN
gs-3921	593	7	,	,	PUNCT
gs-3921	593	8	preventing	prevent	VERB
gs-3921	593	9	discrimination	discrimination	NOUN
gs-3921	593	10	,	,	PUNCT
gs-3921	593	11	and	and	CCONJ
gs-3921	593	12	promoting	promote	VERB
gs-3921	593	13	ethical	ethical	ADJ
gs-3921	593	14	stewardship	stewardship	NOUN
gs-3921	593	15	will	will	AUX
gs-3921	593	16	underpin	underpin	VERB
gs-3921	593	17	public	public	ADJ
gs-3921	593	18	trust	trust	NOUN
gs-3921	593	19	and	and	CCONJ
gs-3921	593	20	sustainable	sustainable	ADJ
gs-3921	593	21	implementation	implementation	NOUN
gs-3921	593	22	.	.	PUNCT
gs-3921	594	1	furthermore	furthermore	ADV
gs-3921	594	2	,	,	PUNCT
gs-3921	594	3	the	the	DET
gs-3921	594	4	integration	integration	NOUN
gs-3921	594	5	of	of	ADP
gs-3921	594	6	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	594	7	with	with	ADP
gs-3921	594	8	pharmacoeconomics	pharmacoeconomic	NOUN
gs-3921	594	9	and	and	CCONJ
gs-3921	594	10	health	health	NOUN
gs-3921	594	11	policy	policy	NOUN
gs-3921	594	12	will	will	AUX
gs-3921	594	13	inform	inform	VERB
gs-3921	594	14	value	value	NOUN
gs-3921	594	15	-	-	PUNCT
gs-3921	594	16	based	base	VERB
gs-3921	594	17	healthcare	healthcare	NOUN
gs-3921	594	18	delivery	delivery	NOUN
gs-3921	594	19	models	model	NOUN
gs-3921	594	20	.	.	PUNCT
gs-3921	595	1	evidence	evidence	NOUN
gs-3921	595	2	-	-	PUNCT
gs-3921	595	3	based	base	VERB
gs-3921	595	4	reimbursement	reimbursement	NOUN
gs-3921	595	5	schemes	scheme	NOUN
gs-3921	595	6	rewarding	reward	VERB
gs-3921	595	7	improved	improve	VERB
gs-3921	595	8	patient	patient	ADJ
gs-3921	595	9	outcomes	outcome	NOUN
gs-3921	595	10	and	and	CCONJ
gs-3921	595	11	cost	cost	NOUN
gs-3921	595	12	savings	saving	NOUN
gs-3921	595	13	will	will	AUX
gs-3921	595	14	incentivize	incentivize	VERB
gs-3921	595	15	healthcare	healthcare	NOUN
gs-3921	595	16	systems	system	NOUN
gs-3921	595	17	to	to	PART
gs-3921	595	18	adopt	adopt	VERB
gs-3921	595	19	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	595	20	-	-	PUNCT
gs-3921	595	21	guided	guide	VERB
gs-3921	595	22	therapies	therapy	NOUN
gs-3921	595	23	widely	widely	ADV
gs-3921	595	24	.	.	PUNCT
gs-3921	596	1	economic	economic	ADJ
gs-3921	596	2	analyses	analysis	NOUN
gs-3921	596	3	incorporating	incorporate	VERB
gs-3921	596	4	societal	societal	ADJ
gs-3921	596	5	benefits	benefit	NOUN
gs-3921	596	6	and	and	CCONJ
gs-3921	596	7	long	long	ADJ
gs-3921	596	8	-	-	PUNCT
gs-3921	596	9	term	term	NOUN
gs-3921	596	10	health	health	NOUN
gs-3921	596	11	impacts	impact	NOUN
gs-3921	596	12	will	will	AUX
gs-3921	596	13	guide	guide	VERB
gs-3921	596	14	resource	resource	NOUN
gs-3921	596	15	allocation	allocation	NOUN
gs-3921	596	16	and	and	CCONJ
gs-3921	596	17	policy	policy	NOUN
gs-3921	596	18	decisions	decision	NOUN
gs-3921	596	19	.	.	PUNCT
gs-3921	597	1	in	in	ADP
gs-3921	597	2	research	research	NOUN
gs-3921	597	3	,	,	PUNCT
gs-3921	597	4	large	large	ADJ
gs-3921	597	5	-	-	PUNCT
gs-3921	597	6	scale	scale	NOUN
gs-3921	597	7	,	,	PUNCT
gs-3921	597	8	multiethnic	multiethnic	ADJ
gs-3921	597	9	cohort	cohort	NOUN
gs-3921	597	10	studies	study	NOUN
gs-3921	597	11	and	and	CCONJ
gs-3921	597	12	biobanks	biobank	NOUN
gs-3921	597	13	enriched	enrich	VERB
gs-3921	597	14	with	with	ADP
gs-3921	597	15	clinical	clinical	ADJ
gs-3921	597	16	,	,	PUNCT
gs-3921	597	17	genetic	genetic	ADJ
gs-3921	597	18	,	,	PUNCT
gs-3921	597	19	and	and	CCONJ
gs-3921	597	20	environmental	environmental	ADJ
gs-3921	597	21	data	datum	NOUN
gs-3921	597	22	will	will	AUX
gs-3921	597	23	enhance	enhance	VERB
gs-3921	597	24	understanding	understanding	NOUN
gs-3921	597	25	of	of	ADP
gs-3921	597	26	diverse	diverse	ADJ
gs-3921	597	27	gene	gene	NOUN
gs-3921	597	28	-	-	PUNCT
gs-3921	597	29	drug	drug	NOUN
gs-3921	597	30	interactions	interaction	NOUN
gs-3921	597	31	.	.	PUNCT
gs-3921	598	1	innovative	innovative	ADJ
gs-3921	598	2	trial	trial	NOUN
gs-3921	598	3	designs	design	NOUN
gs-3921	598	4	,	,	PUNCT
gs-3921	598	5	such	such	ADJ
gs-3921	598	6	as	as	ADP
gs-3921	598	7	adaptive	adaptive	ADJ
gs-3921	598	8	and	and	CCONJ
gs-3921	598	9	pragmatic	pragmatic	ADJ
gs-3921	598	10	clinical	clinical	ADJ
gs-3921	598	11	trials	trial	NOUN
gs-3921	598	12	incorporating	incorporate	VERB
gs-3921	598	13	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	598	14	stratification	stratification	NOUN
gs-3921	598	15	,	,	PUNCT
gs-3921	598	16	will	will	AUX
gs-3921	598	17	accelerate	accelerate	VERB
gs-3921	598	18	the	the	DET
gs-3921	598	19	generation	generation	NOUN
gs-3921	598	20	of	of	ADP
gs-3921	598	21	high	high	ADJ
gs-3921	598	22	-	-	PUNCT
gs-3921	598	23	quality	quality	NOUN
gs-3921	598	24	evidence	evidence	NOUN
gs-3921	598	25	to	to	PART
gs-3921	598	26	inform	inform	VERB
gs-3921	598	27	practice	practice	NOUN
gs-3921	598	28	.	.	PUNCT
gs-3921	599	1	finally	finally	ADV
gs-3921	599	2	,	,	PUNCT
gs-3921	599	3	the	the	DET
gs-3921	599	4	expanding	expand	VERB
gs-3921	599	5	field	field	NOUN
gs-3921	599	6	of	of	ADP
gs-3921	599	7	gene	gene	NOUN
gs-3921	599	8	editing	editing	NOUN
gs-3921	599	9	and	and	CCONJ
gs-3921	599	10	gene	gene	NOUN
gs-3921	599	11	therapy	therapy	NOUN
gs-3921	599	12	may	may	AUX
gs-3921	599	13	offer	offer	VERB
gs-3921	599	14	future	future	ADJ
gs-3921	599	15	avenues	avenue	NOUN
gs-3921	599	16	for	for	ADP
gs-3921	599	17	correcting	correct	VERB
gs-3921	599	18	deleterious	deleterious	ADJ
gs-3921	599	19	genetic	genetic	ADJ
gs-3921	599	20	variants	variant	NOUN
gs-3921	599	21	implicated	implicate	VERB
gs-3921	599	22	in	in	ADP
gs-3921	599	23	drug	drug	NOUN
gs-3921	599	24	toxicity	toxicity	NOUN
gs-3921	599	25	or	or	CCONJ
gs-3921	599	26	nonresponse	nonresponse	NOUN
gs-3921	599	27	,	,	PUNCT
gs-3921	599	28	representing	represent	VERB
gs-3921	599	29	a	a	DET
gs-3921	599	30	revolutionary	revolutionary	ADJ
gs-3921	599	31	frontier	frontier	NOUN
gs-3921	599	32	in	in	ADP
gs-3921	599	33	precision	precision	NOUN
gs-3921	599	34	medicine	medicine	NOUN
gs-3921	599	35	.	.	PUNCT
gs-3921	600	1	the	the	DET
gs-3921	600	2	future	future	ADJ
gs-3921	600	3	prospects	prospect	NOUN
gs-3921	600	4	of	of	ADP
gs-3921	600	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	600	6	and	and	CCONJ
gs-3921	600	7	patient	patient	NOUN
gs-3921	600	8	-	-	PUNCT
gs-3921	600	9	centered	center	VERB
gs-3921	600	10	care	care	NOUN
gs-3921	600	11	are	be	AUX
gs-3921	600	12	vast	vast	ADJ
gs-3921	600	13	and	and	CCONJ
gs-3921	600	14	promising	promising	ADJ
gs-3921	600	15	.	.	PUNCT
gs-3921	601	1	realizing	realize	VERB
gs-3921	601	2	this	this	DET
gs-3921	601	3	potential	potential	ADJ
gs-3921	601	4	requires	require	NOUN
gs-3921	601	5	sustained	sustain	VERB
gs-3921	601	6	multidisciplinary	multidisciplinary	ADJ
gs-3921	601	7	collaboration	collaboration	NOUN
gs-3921	601	8	,	,	PUNCT
gs-3921	601	9	technological	technological	ADJ
gs-3921	601	10	innovation	innovation	NOUN
gs-3921	601	11	,	,	PUNCT
gs-3921	601	12	ethical	ethical	ADJ
gs-3921	601	13	vigilance	vigilance	NOUN
gs-3921	601	14	,	,	PUNCT
gs-3921	601	15	and	and	CCONJ
gs-3921	601	16	commitment	commitment	NOUN
gs-3921	601	17	to	to	ADP
gs-3921	601	18	equitable	equitable	ADJ
gs-3921	601	19	healthcare	healthcare	NOUN
gs-3921	601	20	delivery	delivery	NOUN
gs-3921	601	21	.	.	PUNCT
gs-3921	602	1	as	as	ADP
gs-3921	602	2	these	these	DET
gs-3921	602	3	advances	advance	NOUN
gs-3921	602	4	coalesce	coalesce	VERB
gs-3921	602	5	,	,	PUNCT
gs-3921	602	6	they	they	PRON
gs-3921	602	7	will	will	AUX
gs-3921	602	8	transform	transform	VERB
gs-3921	602	9	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	602	10	into	into	ADP
gs-3921	602	11	a	a	DET
gs-3921	602	12	more	more	ADV
gs-3921	602	13	precise	precise	ADJ
gs-3921	602	14	,	,	PUNCT
gs-3921	602	15	safe	safe	ADJ
gs-3921	602	16	,	,	PUNCT
gs-3921	602	17	and	and	CCONJ
gs-3921	602	18	effective	effective	ADJ
gs-3921	602	19	cornerstone	cornerstone	NOUN
gs-3921	602	20	of	of	ADP
gs-3921	602	21	individualized	individualized	ADJ
gs-3921	602	22	medicine	medicine	NOUN
gs-3921	602	23	.	.	PUNCT
gs-3921	603	1	conclusions	conclusion	NOUN
gs-3921	603	2			VERB
gs-3921	603	3	this	this	DET
gs-3921	603	4	comprehensive	comprehensive	ADJ
gs-3921	603	5	analysis	analysis	NOUN
gs-3921	603	6	highlights	highlight	NOUN
gs-3921	603	7	the	the	DET
gs-3921	603	8	pivotal	pivotal	ADJ
gs-3921	603	9	role	role	NOUN
gs-3921	603	10	of	of	ADP
gs-3921	603	11	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	603	12	and	and	CCONJ
gs-3921	603	13	patient	patient	NOUN
gs-3921	603	14	-	-	PUNCT
gs-3921	603	15	centered	center	VERB
gs-3921	603	16	care	care	NOUN
gs-3921	603	17	approaches	approach	NOUN
gs-3921	603	18	in	in	ADP
gs-3921	603	19	advancing	advance	VERB
gs-3921	603	20	the	the	DET
gs-3921	603	21	safety	safety	NOUN
gs-3921	603	22	and	and	CCONJ
gs-3921	603	23	efficacy	efficacy	NOUN
gs-3921	603	24	of	of	ADP
gs-3921	603	25	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	603	26	.	.	PUNCT
gs-3921	604	1	the	the	DET
gs-3921	604	2	integration	integration	NOUN
gs-3921	604	3	of	of	ADP
gs-3921	604	4	genetic	genetic	ADJ
gs-3921	604	5	insights	insight	NOUN
gs-3921	604	6	into	into	ADP
gs-3921	604	7	clinical	clinical	ADJ
gs-3921	604	8	decision	decision	NOUN
gs-3921	604	9	-	-	PUNCT
gs-3921	604	10	making	making	NOUN
gs-3921	604	11	has	have	AUX
gs-3921	604	12	demonstrated	demonstrate	VERB
gs-3921	604	13	significant	significant	ADJ
gs-3921	604	14	potential	potential	NOUN
gs-3921	604	15	to	to	PART
gs-3921	604	16	mitigate	mitigate	VERB
gs-3921	604	17	medication	medication	NOUN
gs-3921	604	18	-	-	PUNCT
gs-3921	604	19	induced	induce	VERB
gs-3921	604	20	adverse	adverse	ADJ
gs-3921	604	21	effects	effect	NOUN
gs-3921	604	22	and	and	CCONJ
gs-3921	604	23	toxicities	toxicity	NOUN
gs-3921	604	24	,	,	PUNCT
gs-3921	604	25	addressing	address	VERB
gs-3921	604	26	a	a	DET
gs-3921	604	27	critical	critical	ADJ
gs-3921	604	28	unmet	unmet	NOUN
gs-3921	604	29	need	need	NOUN
gs-3921	604	30	in	in	ADP
gs-3921	604	31	modern	modern	ADJ
gs-3921	604	32	medicine	medicine	NOUN
gs-3921	604	33	.	.	PUNCT
gs-3921	605	1	by	by	ADP
gs-3921	605	2	acknowledging	acknowledge	VERB
gs-3921	605	3	the	the	DET
gs-3921	605	4	complexity	complexity	NOUN
gs-3921	605	5	of	of	ADP
gs-3921	605	6	interindividual	interindividual	ADJ
gs-3921	605	7	variability	variability	NOUN
gs-3921	605	8	shaped	shape	VERB
gs-3921	605	9	by	by	ADP
gs-3921	605	10	genetic	genetic	ADJ
gs-3921	605	11	,	,	PUNCT
gs-3921	605	12	environmental	environmental	ADJ
gs-3921	605	13	,	,	PUNCT
gs-3921	605	14	and	and	CCONJ
gs-3921	605	15	psychosocial	psychosocial	ADJ
gs-3921	605	16	determinants	determinant	NOUN
gs-3921	605	17	,	,	PUNCT
gs-3921	605	18	personalized	personalize	VERB
gs-3921	605	19	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	605	20	strategies	strategy	NOUN
gs-3921	605	21	offer	offer	VERB
gs-3921	605	22	a	a	DET
gs-3921	605	23	more	more	ADV
gs-3921	605	24	precise	precise	ADJ
gs-3921	605	25	and	and	CCONJ
gs-3921	605	26	effective	effective	ADJ
gs-3921	605	27	framework	framework	NOUN
gs-3921	605	28	for	for	ADP
gs-3921	605	29	optimizing	optimize	VERB
gs-3921	605	30	drug	drug	NOUN
gs-3921	605	31	therapy	therapy	NOUN
gs-3921	605	32	.	.	PUNCT
gs-3921	606	1			VERB
gs-3921	606	2	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	606	3	systems	system	NOUN
gs-3921	606	4	enriched	enrich	VERB
gs-3921	606	5	with	with	ADP
gs-3921	606	6	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	606	7	data	datum	NOUN
gs-3921	606	8	enable	enable	VERB
gs-3921	606	9	enhanced	enhanced	ADJ
gs-3921	606	10	detection	detection	NOUN
gs-3921	606	11	and	and	CCONJ
gs-3921	606	12	prevention	prevention	NOUN
gs-3921	606	13	of	of	ADP
gs-3921	606	14	adverse	adverse	ADJ
gs-3921	606	15	drug	drug	NOUN
gs-3921	606	16	reactions	reaction	NOUN
gs-3921	606	17	,	,	PUNCT
gs-3921	606	18	fostering	foster	VERB
gs-3921	606	19	safer	safe	ADJ
gs-3921	606	20	medication	medication	NOUN
gs-3921	606	21	use	use	VERB
gs-3921	606	22	georgian	georgian	ADJ
gs-3921	606	23	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	606	24	მეცნიერები	მეცნიერები	NOUN
gs-3921	606	25	ტ.	ტ.	VERB
gs-3921	606	26	7	7	NUM
gs-3921	606	27	n	n	DET
gs-3921	606	28	3	3	NUM
gs-3921	606	29	,	,	PUNCT
gs-3921	606	30	2025	2025	NUM
gs-3921	606	31	252	252	NUM
gs-3921	606	32	across	across	ADP
gs-3921	606	33	diverse	diverse	ADJ
gs-3921	606	34	populations	population	NOUN
gs-3921	606	35	.	.	PUNCT
gs-3921	607	1	nevertheless	nevertheless	ADV
gs-3921	607	2	,	,	PUNCT
gs-3921	607	3	the	the	DET
gs-3921	607	4	full	full	ADJ
gs-3921	607	5	realization	realization	NOUN
gs-3921	607	6	of	of	ADP
gs-3921	607	7	these	these	DET
gs-3921	607	8	benefits	benefit	NOUN
gs-3921	607	9	is	be	AUX
gs-3921	607	10	contingent	contingent	ADJ
gs-3921	607	11	upon	upon	SCONJ
gs-3921	607	12	overcoming	overcome	VERB
gs-3921	607	13	multifaceted	multifaceted	ADJ
gs-3921	607	14	challenges	challenge	NOUN
gs-3921	607	15	including	include	VERB
gs-3921	607	16	limited	limited	ADJ
gs-3921	607	17	clinician	clinician	ADJ
gs-3921	607	18	education	education	NOUN
gs-3921	607	19	,	,	PUNCT
gs-3921	607	20	infrastructural	infrastructural	ADJ
gs-3921	607	21	constraints	constraint	NOUN
gs-3921	607	22	,	,	PUNCT
gs-3921	607	23	economic	economic	ADJ
gs-3921	607	24	barriers	barrier	NOUN
gs-3921	607	25	,	,	PUNCT
gs-3921	607	26	and	and	CCONJ
gs-3921	607	27	ethical	ethical	ADJ
gs-3921	607	28	considerations	consideration	NOUN
gs-3921	607	29	related	relate	VERB
gs-3921	607	30	to	to	ADP
gs-3921	607	31	genetic	genetic	ADJ
gs-3921	607	32	data	datum	NOUN
gs-3921	607	33	privacy	privacy	NOUN
gs-3921	607	34	and	and	CCONJ
gs-3921	607	35	equitable	equitable	ADJ
gs-3921	607	36	access	access	NOUN
gs-3921	607	37	.	.	PUNCT
gs-3921	608	1			ADJ
gs-3921	608	2	technological	technological	ADJ
gs-3921	608	3	innovations	innovation	NOUN
gs-3921	608	4	such	such	ADJ
gs-3921	608	5	as	as	ADP
gs-3921	608	6	clinical	clinical	ADJ
gs-3921	608	7	decision	decision	NOUN
gs-3921	608	8	support	support	NOUN
gs-3921	608	9	tools	tool	NOUN
gs-3921	608	10	,	,	PUNCT
gs-3921	608	11	multi	multi	ADJ
gs-3921	608	12	-	-	ADJ
gs-3921	608	13	omics	omics	ADJ
gs-3921	608	14	integration	integration	NOUN
gs-3921	608	15	,	,	PUNCT
gs-3921	608	16	and	and	CCONJ
gs-3921	608	17	artificial	artificial	ADJ
gs-3921	608	18	intelligence	intelligence	NOUN
gs-3921	608	19	promise	promise	NOUN
gs-3921	608	20	to	to	PART
gs-3921	608	21	revolutionize	revolutionize	VERB
gs-3921	608	22	the	the	DET
gs-3921	608	23	application	application	NOUN
gs-3921	608	24	of	of	ADP
gs-3921	608	25	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	608	26	in	in	ADP
gs-3921	608	27	real	real	ADJ
gs-3921	608	28	-	-	PUNCT
gs-3921	608	29	world	world	NOUN
gs-3921	608	30	settings	setting	NOUN
gs-3921	608	31	.	.	PUNCT
gs-3921	609	1	however	however	ADV
gs-3921	609	2	,	,	PUNCT
gs-3921	609	3	their	their	PRON
gs-3921	609	4	successful	successful	ADJ
gs-3921	609	5	deployment	deployment	NOUN
gs-3921	609	6	requires	require	VERB
gs-3921	609	7	coordinated	coordinate	VERB
gs-3921	609	8	efforts	effort	NOUN
gs-3921	609	9	in	in	ADP
gs-3921	609	10	healthcare	healthcare	NOUN
gs-3921	609	11	system	system	NOUN
gs-3921	609	12	redesign	redesign	NOUN
gs-3921	609	13	,	,	PUNCT
gs-3921	609	14	robust	robust	ADJ
gs-3921	609	15	regulatory	regulatory	ADJ
gs-3921	609	16	frameworks	framework	NOUN
gs-3921	609	17	,	,	PUNCT
gs-3921	609	18	and	and	CCONJ
gs-3921	609	19	patient	patient	ADJ
gs-3921	609	20	engagement	engagement	NOUN
gs-3921	609	21	initiatives	initiative	NOUN
gs-3921	609	22	that	that	PRON
gs-3921	609	23	prioritize	prioritize	VERB
gs-3921	609	24	transparency	transparency	NOUN
gs-3921	609	25	and	and	CCONJ
gs-3921	609	26	shared	share	VERB
gs-3921	609	27	decision	decision	NOUN
gs-3921	609	28	-	-	PUNCT
gs-3921	609	29	making	making	NOUN
gs-3921	609	30	.	.	PUNCT
gs-3921	610	1			ADJ
gs-3921	610	2	equity	equity	NOUN
gs-3921	610	3	remains	remain	VERB
gs-3921	610	4	a	a	DET
gs-3921	610	5	paramount	paramount	ADJ
gs-3921	610	6	concern	concern	NOUN
gs-3921	610	7	,	,	PUNCT
gs-3921	610	8	necessitating	necessitate	VERB
gs-3921	610	9	deliberate	deliberate	ADJ
gs-3921	610	10	strategies	strategy	NOUN
gs-3921	610	11	to	to	PART
gs-3921	610	12	ensure	ensure	VERB
gs-3921	610	13	that	that	SCONJ
gs-3921	610	14	advances	advance	NOUN
gs-3921	610	15	in	in	ADP
gs-3921	610	16	personalized	personalized	ADJ
gs-3921	610	17	medicine	medicine	NOUN
gs-3921	610	18	benefit	benefit	VERB
gs-3921	610	19	all	all	DET
gs-3921	610	20	populations	population	NOUN
gs-3921	610	21	,	,	PUNCT
gs-3921	610	22	particularly	particularly	ADV
gs-3921	610	23	historically	historically	ADV
gs-3921	610	24	underserved	underserved	ADJ
gs-3921	610	25	and	and	CCONJ
gs-3921	610	26	genetically	genetically	ADV
gs-3921	610	27	diverse	diverse	ADJ
gs-3921	610	28	groups	group	NOUN
gs-3921	610	29	.	.	PUNCT
gs-3921	611	1	international	international	ADJ
gs-3921	611	2	collaboration	collaboration	NOUN
gs-3921	611	3	,	,	PUNCT
gs-3921	611	4	policy	policy	NOUN
gs-3921	611	5	harmonization	harmonization	NOUN
gs-3921	611	6	,	,	PUNCT
gs-3921	611	7	and	and	CCONJ
gs-3921	611	8	culturally	culturally	ADV
gs-3921	611	9	competent	competent	ADJ
gs-3921	611	10	care	care	NOUN
gs-3921	611	11	models	model	NOUN
gs-3921	611	12	are	be	AUX
gs-3921	611	13	essential	essential	ADJ
gs-3921	611	14	components	component	NOUN
gs-3921	611	15	of	of	ADP
gs-3921	611	16	this	this	DET
gs-3921	611	17	endeavor	endeavor	NOUN
gs-3921	611	18	.	.	PUNCT
gs-3921	612	1			VERB
gs-3921	612	2	in	in	ADP
gs-3921	612	3	sum	sum	NOUN
gs-3921	612	4	,	,	PUNCT
gs-3921	612	5	the	the	DET
gs-3921	612	6	fusion	fusion	NOUN
gs-3921	612	7	of	of	ADP
gs-3921	612	8	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	612	9	with	with	ADP
gs-3921	612	10	patient	patient	NOUN
gs-3921	612	11	-	-	PUNCT
gs-3921	612	12	centered	center	VERB
gs-3921	612	13	care	care	NOUN
gs-3921	612	14	and	and	CCONJ
gs-3921	612	15	advanced	advanced	ADJ
gs-3921	612	16	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	612	17	heralds	herald	VERB
gs-3921	612	18	a	a	DET
gs-3921	612	19	transformative	transformative	ADJ
gs-3921	612	20	era	era	NOUN
gs-3921	612	21	in	in	ADP
gs-3921	612	22	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	612	23	.	.	PUNCT
gs-3921	613	1	sustained	sustain	VERB
gs-3921	613	2	interdisciplinary	interdisciplinary	ADJ
gs-3921	613	3	collaboration	collaboration	NOUN
gs-3921	613	4	,	,	PUNCT
gs-3921	613	5	ethical	ethical	ADJ
gs-3921	613	6	stewardship	stewardship	NOUN
gs-3921	613	7	,	,	PUNCT
gs-3921	613	8	and	and	CCONJ
gs-3921	613	9	innovative	innovative	ADJ
gs-3921	613	10	research	research	NOUN
gs-3921	613	11	will	will	AUX
gs-3921	613	12	be	be	AUX
gs-3921	613	13	indispensable	indispensable	ADJ
gs-3921	613	14	to	to	PART
gs-3921	613	15	translate	translate	VERB
gs-3921	613	16	scientific	scientific	ADJ
gs-3921	613	17	discoveries	discovery	NOUN
gs-3921	613	18	into	into	ADP
gs-3921	613	19	routine	routine	ADJ
gs-3921	613	20	clinical	clinical	ADJ
gs-3921	613	21	practice	practice	NOUN
gs-3921	613	22	,	,	PUNCT
gs-3921	613	23	ultimately	ultimately	ADV
gs-3921	613	24	improving	improve	VERB
gs-3921	613	25	patient	patient	ADJ
gs-3921	613	26	outcomes	outcome	NOUN
gs-3921	613	27	and	and	CCONJ
gs-3921	613	28	shaping	shape	VERB
gs-3921	613	29	the	the	DET
gs-3921	613	30	future	future	NOUN
gs-3921	613	31	of	of	ADP
gs-3921	613	32	precision	precision	NOUN
gs-3921	613	33	medicine	medicine	NOUN
gs-3921	613	34	.	.	PUNCT
gs-3921	614	1			VERB
gs-3921	614	2	the	the	DET
gs-3921	614	3	integration	integration	NOUN
gs-3921	614	4	of	of	ADP
gs-3921	614	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	614	6	insights	insight	NOUN
gs-3921	614	7	with	with	ADP
gs-3921	614	8	patient	patient	NOUN
gs-3921	614	9	-	-	PUNCT
gs-3921	614	10	centered	center	VERB
gs-3921	614	11	care	care	NOUN
gs-3921	614	12	models	model	NOUN
gs-3921	614	13	represents	represent	VERB
gs-3921	614	14	a	a	DET
gs-3921	614	15	transformative	transformative	ADJ
gs-3921	614	16	advancement	advancement	NOUN
gs-3921	614	17	in	in	ADP
gs-3921	614	18	modern	modern	ADJ
gs-3921	614	19	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	614	20	,	,	PUNCT
gs-3921	614	21	offering	offer	VERB
gs-3921	614	22	unparalleled	unparalleled	ADJ
gs-3921	614	23	opportunities	opportunity	NOUN
gs-3921	614	24	to	to	PART
gs-3921	614	25	enhance	enhance	VERB
gs-3921	614	26	medication	medication	NOUN
gs-3921	614	27	safety	safety	NOUN
gs-3921	614	28	,	,	PUNCT
gs-3921	614	29	efficacy	efficacy	NOUN
gs-3921	614	30	,	,	PUNCT
gs-3921	614	31	and	and	CCONJ
gs-3921	614	32	overall	overall	ADJ
gs-3921	614	33	patient	patient	ADJ
gs-3921	614	34	outcomes	outcome	NOUN
gs-3921	614	35	.	.	PUNCT
gs-3921	615	1	this	this	DET
gs-3921	615	2	comprehensive	comprehensive	ADJ
gs-3921	615	3	analysis	analysis	NOUN
gs-3921	615	4	underscores	underscore	VERB
gs-3921	615	5	that	that	SCONJ
gs-3921	615	6	interindividual	interindividual	ADJ
gs-3921	615	7	variability	variability	NOUN
gs-3921	615	8	in	in	ADP
gs-3921	615	9	drug	drug	NOUN
gs-3921	615	10	response	response	NOUN
gs-3921	615	11	—	—	PUNCT
gs-3921	615	12	rooted	root	VERB
gs-3921	615	13	in	in	ADP
gs-3921	615	14	genetic	genetic	ADJ
gs-3921	615	15	polymorphisms	polymorphism	NOUN
gs-3921	615	16	and	and	CCONJ
gs-3921	615	17	influenced	influence	VERB
gs-3921	615	18	by	by	ADP
gs-3921	615	19	environmental	environmental	ADJ
gs-3921	615	20	and	and	CCONJ
gs-3921	615	21	clinical	clinical	ADJ
gs-3921	615	22	factors	factor	NOUN
gs-3921	615	23	—	—	PUNCT
gs-3921	615	24	cannot	cannot	VERB
gs-3921	615	25	be	be	AUX
gs-3921	615	26	adequately	adequately	ADV
gs-3921	615	27	addressed	address	VERB
gs-3921	615	28	by	by	ADP
gs-3921	615	29	conventional	conventional	ADJ
gs-3921	615	30	,	,	PUNCT
gs-3921	615	31	empirical	empirical	ADJ
gs-3921	615	32	prescribing	prescribing	NOUN
gs-3921	615	33	practices	practice	NOUN
gs-3921	615	34	.	.	PUNCT
gs-3921	616	1	personalized	personalize	VERB
gs-3921	616	2	approaches	approach	NOUN
gs-3921	616	3	informed	inform	VERB
gs-3921	616	4	by	by	ADP
gs-3921	616	5	genetic	genetic	ADJ
gs-3921	616	6	data	datum	NOUN
gs-3921	616	7	provide	provide	VERB
gs-3921	616	8	a	a	DET
gs-3921	616	9	pathway	pathway	NOUN
gs-3921	616	10	toward	toward	ADP
gs-3921	616	11	precision	precision	NOUN
gs-3921	616	12	medicine	medicine	NOUN
gs-3921	616	13	that	that	PRON
gs-3921	616	14	anticipates	anticipate	VERB
gs-3921	616	15	and	and	CCONJ
gs-3921	616	16	mitigates	mitigate	VERB
gs-3921	616	17	adverse	adverse	ADJ
gs-3921	616	18	drug	drug	NOUN
gs-3921	616	19	reactions	reaction	NOUN
gs-3921	616	20	,	,	PUNCT
gs-3921	616	21	optimizes	optimize	VERB
gs-3921	616	22	therapeutic	therapeutic	ADJ
gs-3921	616	23	efficacy	efficacy	NOUN
gs-3921	616	24	,	,	PUNCT
gs-3921	616	25	and	and	CCONJ
gs-3921	616	26	supports	support	VERB
gs-3921	616	27	informed	inform	VERB
gs-3921	616	28	,	,	PUNCT
gs-3921	616	29	shared	shared	ADJ
gs-3921	616	30	decisionmaking	decisionmaking	NOUN
gs-3921	616	31	.	.	PUNCT
gs-3921	617	1			ADJ
gs-3921	617	2	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	617	3	holds	hold	VERB
gs-3921	617	4	particular	particular	ADJ
gs-3921	617	5	promise	promise	NOUN
gs-3921	617	6	for	for	ADP
gs-3921	617	7	high	high	ADJ
gs-3921	617	8	-	-	PUNCT
gs-3921	617	9	risk	risk	NOUN
gs-3921	617	10	drug	drug	NOUN
gs-3921	617	11	classes	class	NOUN
gs-3921	617	12	and	and	CCONJ
gs-3921	617	13	populations	population	NOUN
gs-3921	617	14	predisposed	predispose	VERB
gs-3921	617	15	to	to	ADP
gs-3921	617	16	severe	severe	ADJ
gs-3921	617	17	toxicities	toxicity	NOUN
gs-3921	617	18	,	,	PUNCT
gs-3921	617	19	such	such	ADJ
gs-3921	617	20	as	as	ADP
gs-3921	617	21	those	those	PRON
gs-3921	617	22	with	with	ADP
gs-3921	617	23	variants	variant	NOUN
gs-3921	617	24	affecting	affect	VERB
gs-3921	617	25	drug	drug	NOUN
gs-3921	617	26	metabolism	metabolism	NOUN
gs-3921	617	27	enzymes	enzyme	NOUN
gs-3921	617	28	and	and	CCONJ
gs-3921	617	29	immune	immune	ADJ
gs-3921	617	30	response	response	NOUN
gs-3921	617	31	genes	gene	NOUN
gs-3921	617	32	.	.	PUNCT
gs-3921	618	1	the	the	DET
gs-3921	618	2	alignment	alignment	NOUN
gs-3921	618	3	of	of	ADP
gs-3921	618	4	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	618	5	testing	testing	NOUN
gs-3921	618	6	with	with	ADP
gs-3921	618	7	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	618	8	initiatives	initiative	NOUN
gs-3921	618	9	enhances	enhance	VERB
gs-3921	618	10	real	real	ADJ
gs-3921	618	11	-	-	PUNCT
gs-3921	618	12	time	time	NOUN
gs-3921	618	13	safety	safety	NOUN
gs-3921	618	14	monitoring	monitoring	NOUN
gs-3921	618	15	and	and	CCONJ
gs-3921	618	16	supports	support	VERB
gs-3921	618	17	proactive	proactive	ADJ
gs-3921	618	18	interventions	intervention	NOUN
gs-3921	618	19	.	.	PUNCT
gs-3921	619	1	these	these	DET
gs-3921	619	2	advancements	advancement	NOUN
gs-3921	619	3	necessitate	necessitate	ADJ
gs-3921	619	4	the	the	DET
gs-3921	619	5	development	development	NOUN
gs-3921	619	6	and	and	CCONJ
gs-3921	619	7	deployment	deployment	NOUN
gs-3921	619	8	of	of	ADP
gs-3921	619	9	sophisticated	sophisticated	ADJ
gs-3921	619	10	clinical	clinical	ADJ
gs-3921	619	11	decision	decision	NOUN
gs-3921	619	12	support	support	NOUN
gs-3921	619	13	systems	system	NOUN
gs-3921	619	14	that	that	PRON
gs-3921	619	15	integrate	integrate	VERB
gs-3921	619	16	seamlessly	seamlessly	ADV
gs-3921	619	17	with	with	ADP
gs-3921	619	18	electronic	electronic	ADJ
gs-3921	619	19	health	health	NOUN
gs-3921	619	20	records	record	NOUN
gs-3921	619	21	to	to	PART
gs-3921	619	22	guide	guide	VERB
gs-3921	619	23	clinicians	clinician	NOUN
gs-3921	619	24	in	in	ADP
gs-3921	619	25	complex	complex	ADJ
gs-3921	619	26	therapeutic	therapeutic	ADJ
gs-3921	619	27	scenarios	scenario	NOUN
gs-3921	619	28	.	.	PUNCT
gs-3921	620	1			VERB
gs-3921	620	2	however	however	ADV
gs-3921	620	3	,	,	PUNCT
gs-3921	620	4	realizing	realize	VERB
gs-3921	620	5	the	the	DET
gs-3921	620	6	full	full	ADJ
gs-3921	620	7	potential	potential	NOUN
gs-3921	620	8	of	of	ADP
gs-3921	620	9	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	620	10	requires	require	VERB
gs-3921	620	11	addressing	address	VERB
gs-3921	620	12	persistent	persistent	ADJ
gs-3921	620	13	systemic	systemic	ADJ
gs-3921	620	14	challenges	challenge	NOUN
gs-3921	620	15	.	.	PUNCT
gs-3921	621	1	education	education	NOUN
gs-3921	621	2	and	and	CCONJ
gs-3921	621	3	training	training	NOUN
gs-3921	621	4	gaps	gap	NOUN
gs-3921	621	5	among	among	ADP
gs-3921	621	6	healthcare	healthcare	NOUN
gs-3921	621	7	providers	provider	NOUN
gs-3921	621	8	hinder	hinder	VERB
gs-3921	621	9	widespread	widespread	ADJ
gs-3921	621	10	adoption	adoption	NOUN
gs-3921	621	11	,	,	PUNCT
gs-3921	621	12	highlighting	highlight	VERB
gs-3921	621	13	the	the	DET
gs-3921	621	14	urgent	urgent	ADJ
gs-3921	621	15	need	need	NOUN
gs-3921	621	16	for	for	ADP
gs-3921	621	17	targeted	target	VERB
gs-3921	621	18	curricular	curricular	ADJ
gs-3921	621	19	georgian	georgian	ADJ
gs-3921	621	20	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	621	21	მეცნიერები	მეცნიერები	NOUN
gs-3921	621	22	ტ.	ტ.	VERB
gs-3921	621	23	7	7	NUM
gs-3921	621	24	n	n	DET
gs-3921	621	25	3	3	NUM
gs-3921	621	26	,	,	PUNCT
gs-3921	621	27	2025	2025	NUM
gs-3921	621	28	253	253	NUM
gs-3921	621	29	reforms	reform	NOUN
gs-3921	621	30	and	and	CCONJ
gs-3921	621	31	continuous	continuous	ADJ
gs-3921	621	32	professional	professional	ADJ
gs-3921	621	33	development	development	NOUN
gs-3921	621	34	.	.	PUNCT
gs-3921	622	1	economic	economic	ADJ
gs-3921	622	2	considerations	consideration	NOUN
gs-3921	622	3	,	,	PUNCT
gs-3921	622	4	including	include	VERB
gs-3921	622	5	cost	cost	NOUN
gs-3921	622	6	-	-	PUNCT
gs-3921	622	7	effectiveness	effectiveness	NOUN
gs-3921	622	8	and	and	CCONJ
gs-3921	622	9	reimbursement	reimbursement	NOUN
gs-3921	622	10	policies	policy	NOUN
gs-3921	622	11	,	,	PUNCT
gs-3921	622	12	remain	remain	VERB
gs-3921	622	13	critical	critical	ADJ
gs-3921	622	14	barriers	barrier	NOUN
gs-3921	622	15	,	,	PUNCT
gs-3921	622	16	particularly	particularly	ADV
gs-3921	622	17	in	in	ADP
gs-3921	622	18	resource	resource	NOUN
gs-3921	622	19	-	-	PUNCT
gs-3921	622	20	constrained	constrain	VERB
gs-3921	622	21	settings	setting	NOUN
gs-3921	622	22	.	.	PUNCT
gs-3921	623	1	furthermore	furthermore	ADV
gs-3921	623	2	,	,	PUNCT
gs-3921	623	3	ethical	ethical	ADJ
gs-3921	623	4	,	,	PUNCT
gs-3921	623	5	legal	legal	ADJ
gs-3921	623	6	,	,	PUNCT
gs-3921	623	7	and	and	CCONJ
gs-3921	623	8	social	social	ADJ
gs-3921	623	9	issues	issue	NOUN
gs-3921	623	10	related	relate	VERB
gs-3921	623	11	to	to	ADP
gs-3921	623	12	genetic	genetic	ADJ
gs-3921	623	13	privacy	privacy	NOUN
gs-3921	623	14	,	,	PUNCT
gs-3921	623	15	data	datum	NOUN
gs-3921	623	16	security	security	NOUN
gs-3921	623	17	,	,	PUNCT
gs-3921	623	18	and	and	CCONJ
gs-3921	623	19	equitable	equitable	ADJ
gs-3921	623	20	access	access	NOUN
gs-3921	623	21	demand	demand	NOUN
gs-3921	623	22	robust	robust	ADJ
gs-3921	623	23	policy	policy	NOUN
gs-3921	623	24	frameworks	framework	NOUN
gs-3921	623	25	and	and	CCONJ
gs-3921	623	26	patient	patient	NOUN
gs-3921	623	27	-	-	PUNCT
gs-3921	623	28	centered	center	VERB
gs-3921	623	29	communication	communication	NOUN
gs-3921	623	30	strategies	strategy	NOUN
gs-3921	623	31	to	to	PART
gs-3921	623	32	maintain	maintain	VERB
gs-3921	623	33	trust	trust	NOUN
gs-3921	623	34	and	and	CCONJ
gs-3921	623	35	promote	promote	VERB
gs-3921	623	36	inclusive	inclusive	ADJ
gs-3921	623	37	implementation	implementation	NOUN
gs-3921	623	38	.	.	PUNCT
gs-3921	624	1			ADJ
gs-3921	624	2	technological	technological	ADJ
gs-3921	624	3	innovations	innovation	NOUN
gs-3921	624	4	such	such	ADJ
gs-3921	624	5	as	as	ADP
gs-3921	624	6	next	next	ADJ
gs-3921	624	7	-	-	PUNCT
gs-3921	624	8	generation	generation	NOUN
gs-3921	624	9	sequencing	sequencing	NOUN
gs-3921	624	10	,	,	PUNCT
gs-3921	624	11	multi	multi	ADJ
gs-3921	624	12	-	-	ADJ
gs-3921	624	13	omics	omics	ADJ
gs-3921	624	14	integration	integration	NOUN
gs-3921	624	15	,	,	PUNCT
gs-3921	624	16	and	and	CCONJ
gs-3921	624	17	artificial	artificial	ADJ
gs-3921	624	18	intelligence	intelligence	NOUN
gs-3921	624	19	-	-	PUNCT
gs-3921	624	20	driven	drive	VERB
gs-3921	624	21	analytics	analytic	NOUN
gs-3921	624	22	are	be	AUX
gs-3921	624	23	rapidly	rapidly	ADV
gs-3921	624	24	expanding	expand	VERB
gs-3921	624	25	the	the	DET
gs-3921	624	26	scope	scope	NOUN
gs-3921	624	27	and	and	CCONJ
gs-3921	624	28	depth	depth	NOUN
gs-3921	624	29	of	of	ADP
gs-3921	624	30	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	624	31	applications	application	NOUN
gs-3921	624	32	.	.	PUNCT
gs-3921	625	1	these	these	DET
gs-3921	625	2	tools	tool	NOUN
gs-3921	625	3	will	will	AUX
gs-3921	625	4	facilitate	facilitate	VERB
gs-3921	625	5	a	a	DET
gs-3921	625	6	more	more	ADV
gs-3921	625	7	comprehensive	comprehensive	ADJ
gs-3921	625	8	understanding	understanding	NOUN
gs-3921	625	9	of	of	ADP
gs-3921	625	10	drug	drug	NOUN
gs-3921	625	11	response	response	NOUN
gs-3921	625	12	variability	variability	NOUN
gs-3921	625	13	,	,	PUNCT
gs-3921	625	14	encompassing	encompass	VERB
gs-3921	625	15	complex	complex	ADJ
gs-3921	625	16	gene	gene	NOUN
gs-3921	625	17	-	-	PUNCT
gs-3921	625	18	gene	gene	NOUN
gs-3921	625	19	and	and	CCONJ
gs-3921	625	20	gene	gene	NOUN
gs-3921	625	21	-	-	PUNCT
gs-3921	625	22	environment	environment	NOUN
gs-3921	625	23	interactions	interaction	NOUN
gs-3921	625	24	.	.	PUNCT
gs-3921	626	1	the	the	DET
gs-3921	626	2	incorporation	incorporation	NOUN
gs-3921	626	3	of	of	ADP
gs-3921	626	4	patient	patient	NOUN
gs-3921	626	5	-	-	PUNCT
gs-3921	626	6	generated	generate	VERB
gs-3921	626	7	health	health	NOUN
gs-3921	626	8	data	datum	NOUN
gs-3921	626	9	through	through	ADP
gs-3921	626	10	wearable	wearable	ADJ
gs-3921	626	11	devices	device	NOUN
gs-3921	626	12	and	and	CCONJ
gs-3921	626	13	mobile	mobile	NOUN
gs-3921	626	14	platforms	platform	NOUN
gs-3921	626	15	will	will	AUX
gs-3921	626	16	further	far	ADV
gs-3921	626	17	personalize	personalize	VERB
gs-3921	626	18	therapeutic	therapeutic	ADJ
gs-3921	626	19	monitoring	monitoring	NOUN
gs-3921	626	20	and	and	CCONJ
gs-3921	626	21	intervention	intervention	NOUN
gs-3921	626	22	.	.	PUNCT
gs-3921	627	1			VERB
gs-3921	627	2	importantly	importantly	ADV
gs-3921	627	3	,	,	PUNCT
gs-3921	627	4	health	health	NOUN
gs-3921	627	5	equity	equity	NOUN
gs-3921	627	6	must	must	AUX
gs-3921	627	7	remain	remain	VERB
gs-3921	627	8	a	a	DET
gs-3921	627	9	guiding	guide	VERB
gs-3921	627	10	principle	principle	NOUN
gs-3921	627	11	throughout	throughout	ADP
gs-3921	627	12	the	the	DET
gs-3921	627	13	evolution	evolution	NOUN
gs-3921	627	14	of	of	ADP
gs-3921	627	15	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	627	16	.	.	PUNCT
gs-3921	628	1	inclusive	inclusive	ADJ
gs-3921	628	2	research	research	NOUN
gs-3921	628	3	practices	practice	NOUN
gs-3921	628	4	that	that	PRON
gs-3921	628	5	incorporate	incorporate	VERB
gs-3921	628	6	diverse	diverse	ADJ
gs-3921	628	7	populations	population	NOUN
gs-3921	628	8	,	,	PUNCT
gs-3921	628	9	culturally	culturally	ADV
gs-3921	628	10	sensitive	sensitive	ADJ
gs-3921	628	11	healthcare	healthcare	NOUN
gs-3921	628	12	delivery	delivery	NOUN
gs-3921	628	13	,	,	PUNCT
gs-3921	628	14	and	and	CCONJ
gs-3921	628	15	accessible	accessible	ADJ
gs-3921	628	16	testing	testing	NOUN
gs-3921	628	17	services	service	NOUN
gs-3921	628	18	are	be	AUX
gs-3921	628	19	essential	essential	ADJ
gs-3921	628	20	to	to	PART
gs-3921	628	21	avoid	avoid	VERB
gs-3921	628	22	exacerbating	exacerbate	VERB
gs-3921	628	23	existing	exist	VERB
gs-3921	628	24	disparities	disparity	NOUN
gs-3921	628	25	in	in	ADP
gs-3921	628	26	medication	medication	NOUN
gs-3921	628	27	safety	safety	NOUN
gs-3921	628	28	and	and	CCONJ
gs-3921	628	29	therapeutic	therapeutic	ADJ
gs-3921	628	30	outcomes	outcome	NOUN
gs-3921	628	31	.	.	PUNCT
gs-3921	629	1	international	international	ADJ
gs-3921	629	2	collaboration	collaboration	NOUN
gs-3921	629	3	and	and	CCONJ
gs-3921	629	4	regulatory	regulatory	ADJ
gs-3921	629	5	harmonization	harmonization	NOUN
gs-3921	629	6	will	will	AUX
gs-3921	629	7	be	be	AUX
gs-3921	629	8	pivotal	pivotal	ADJ
gs-3921	629	9	in	in	ADP
gs-3921	629	10	scaling	scale	VERB
gs-3921	629	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	629	12	advances	advance	NOUN
gs-3921	629	13	globally	globally	ADV
gs-3921	629	14	and	and	CCONJ
gs-3921	629	15	ensuring	ensure	VERB
gs-3921	629	16	quality	quality	NOUN
gs-3921	629	17	and	and	CCONJ
gs-3921	629	18	consistency	consistency	NOUN
gs-3921	629	19	.	.	PUNCT
gs-3921	630	1			VERB
gs-3921	630	2	in	in	ADP
gs-3921	630	3	conclusion	conclusion	NOUN
gs-3921	630	4	,	,	PUNCT
gs-3921	630	5	the	the	DET
gs-3921	630	6	convergence	convergence	NOUN
gs-3921	630	7	of	of	ADP
gs-3921	630	8	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	630	9	,	,	PUNCT
gs-3921	630	10	patient	patient	NOUN
gs-3921	630	11	-	-	PUNCT
gs-3921	630	12	centered	center	VERB
gs-3921	630	13	care	care	NOUN
gs-3921	630	14	,	,	PUNCT
gs-3921	630	15	and	and	CCONJ
gs-3921	630	16	advanced	advanced	ADJ
gs-3921	630	17	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	630	18	heralds	herald	VERB
gs-3921	630	19	a	a	DET
gs-3921	630	20	new	new	ADJ
gs-3921	630	21	era	era	NOUN
gs-3921	630	22	in	in	ADP
gs-3921	630	23	precision	precision	NOUN
gs-3921	630	24	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	630	25	.	.	PUNCT
gs-3921	631	1	multidisciplinary	multidisciplinary	ADJ
gs-3921	631	2	collaboration	collaboration	NOUN
gs-3921	631	3	among	among	ADP
gs-3921	631	4	clinicians	clinician	NOUN
gs-3921	631	5	,	,	PUNCT
gs-3921	631	6	researchers	researcher	NOUN
gs-3921	631	7	,	,	PUNCT
gs-3921	631	8	policymakers	policymaker	NOUN
gs-3921	631	9	,	,	PUNCT
gs-3921	631	10	and	and	CCONJ
gs-3921	631	11	patients	patient	NOUN
gs-3921	631	12	is	be	AUX
gs-3921	631	13	essential	essential	ADJ
gs-3921	631	14	to	to	PART
gs-3921	631	15	overcome	overcome	VERB
gs-3921	631	16	current	current	ADJ
gs-3921	631	17	barriers	barrier	NOUN
gs-3921	631	18	and	and	CCONJ
gs-3921	631	19	translate	translate	VERB
gs-3921	631	20	scientific	scientific	ADJ
gs-3921	631	21	progress	progress	NOUN
gs-3921	631	22	into	into	ADP
gs-3921	631	23	routine	routine	ADJ
gs-3921	631	24	,	,	PUNCT
gs-3921	631	25	equitable	equitable	ADJ
gs-3921	631	26	clinical	clinical	ADJ
gs-3921	631	27	practice	practice	NOUN
gs-3921	631	28	.	.	PUNCT
gs-3921	632	1	through	through	ADP
gs-3921	632	2	sustained	sustained	ADJ
gs-3921	632	3	effort	effort	NOUN
gs-3921	632	4	and	and	CCONJ
gs-3921	632	5	innovation	innovation	NOUN
gs-3921	632	6	,	,	PUNCT
gs-3921	632	7	personalized	personalized	ADJ
gs-3921	632	8	medicine	medicine	NOUN
gs-3921	632	9	can	can	AUX
gs-3921	632	10	fulfill	fulfill	VERB
gs-3921	632	11	its	its	PRON
gs-3921	632	12	promise	promise	NOUN
gs-3921	632	13	of	of	ADP
gs-3921	632	14	safer	safe	ADJ
gs-3921	632	15	,	,	PUNCT
gs-3921	632	16	more	more	ADV
gs-3921	632	17	effective	effective	ADJ
gs-3921	632	18	,	,	PUNCT
gs-3921	632	19	and	and	CCONJ
gs-3921	632	20	individualized	individualized	ADJ
gs-3921	632	21	therapeutic	therapeutic	ADJ
gs-3921	632	22	strategies	strategy	NOUN
gs-3921	632	23	that	that	PRON
gs-3921	632	24	improve	improve	VERB
gs-3921	632	25	health	health	NOUN
gs-3921	632	26	outcomes	outcome	NOUN
gs-3921	632	27	worldwide	worldwide	ADV
gs-3921	632	28	.	.	PUNCT
gs-3921	633	1	recommendations	recommendation	NOUN
gs-3921	633	2	in	in	ADP
gs-3921	633	3	light	light	NOUN
gs-3921	633	4	of	of	ADP
gs-3921	633	5	the	the	DET
gs-3921	633	6	findings	finding	NOUN
gs-3921	633	7	and	and	CCONJ
gs-3921	633	8	in	in	ADP
gs-3921	633	9	-	-	PUNCT
gs-3921	633	10	depth	depth	NOUN
gs-3921	633	11	analysis	analysis	NOUN
gs-3921	633	12	presented	present	VERB
gs-3921	633	13	,	,	PUNCT
gs-3921	633	14	the	the	DET
gs-3921	633	15	following	follow	VERB
gs-3921	633	16	recommendations	recommendation	NOUN
gs-3921	633	17	are	be	AUX
gs-3921	633	18	proposed	propose	VERB
gs-3921	633	19	to	to	PART
gs-3921	633	20	guide	guide	VERB
gs-3921	633	21	clinical	clinical	ADJ
gs-3921	633	22	practice	practice	NOUN
gs-3921	633	23	,	,	PUNCT
gs-3921	633	24	research	research	NOUN
gs-3921	633	25	priorities	priority	NOUN
gs-3921	633	26	,	,	PUNCT
gs-3921	633	27	health	health	NOUN
gs-3921	633	28	policy	policy	NOUN
gs-3921	633	29	development	development	NOUN
gs-3921	633	30	,	,	PUNCT
gs-3921	633	31	and	and	CCONJ
gs-3921	633	32	educational	educational	ADJ
gs-3921	633	33	strategies	strategy	NOUN
gs-3921	633	34	related	relate	VERB
gs-3921	633	35	to	to	ADP
gs-3921	633	36	the	the	DET
gs-3921	633	37	integration	integration	NOUN
gs-3921	633	38	of	of	ADP
gs-3921	633	39	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	633	40	and	and	CCONJ
gs-3921	633	41	patient	patient	NOUN
gs-3921	633	42	-	-	PUNCT
gs-3921	633	43	centered	center	VERB
gs-3921	633	44	care	care	NOUN
gs-3921	633	45	into	into	ADP
gs-3921	633	46	modern	modern	ADJ
gs-3921	633	47	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	633	48	and	and	CCONJ
gs-3921	633	49	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	633	50	systems	system	NOUN
gs-3921	633	51	.	.	PUNCT
gs-3921	634	1			VERB
gs-3921	634	2	strengthen	strengthen	VERB
gs-3921	634	3	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	634	4	integration	integration	NOUN
gs-3921	634	5	in	in	ADP
gs-3921	634	6	clinical	clinical	ADJ
gs-3921	634	7	practice	practice	NOUN
gs-3921	634	8	:	:	PUNCT
gs-3921	634	9	healthcare	healthcare	NOUN
gs-3921	634	10	systems	system	NOUN
gs-3921	634	11	should	should	AUX
gs-3921	634	12	prioritize	prioritize	VERB
gs-3921	634	13	the	the	DET
gs-3921	634	14	structured	structured	ADJ
gs-3921	634	15	incorporation	incorporation	NOUN
gs-3921	634	16	of	of	ADP
gs-3921	634	17	validated	validated	ADJ
gs-3921	634	18	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	634	19	testing	testing	NOUN
gs-3921	634	20	into	into	ADP
gs-3921	634	21	routine	routine	ADJ
gs-3921	634	22	care	care	NOUN
gs-3921	634	23	,	,	PUNCT
gs-3921	634	24	especially	especially	ADV
gs-3921	634	25	for	for	ADP
gs-3921	634	26	drugs	drug	NOUN
gs-3921	634	27	with	with	ADP
gs-3921	634	28	known	know	VERB
gs-3921	634	29	gene	gene	NOUN
gs-3921	634	30	-	-	PUNCT
gs-3921	634	31	drug	drug	NOUN
gs-3921	634	32	associations	association	NOUN
gs-3921	634	33	.	.	PUNCT
gs-3921	635	1	this	this	PRON
gs-3921	635	2	includes	include	VERB
gs-3921	635	3	the	the	DET
gs-3921	635	4	development	development	NOUN
gs-3921	635	5	and	and	CCONJ
gs-3921	635	6	implementation	implementation	NOUN
gs-3921	635	7	of	of	ADP
gs-3921	635	8	preemptive	preemptive	ADJ
gs-3921	635	9	genotyping	genotyping	NOUN
gs-3921	635	10	programs	program	NOUN
gs-3921	635	11	for	for	ADP
gs-3921	635	12	patients	patient	NOUN
gs-3921	635	13	at	at	ADP
gs-3921	635	14	risk	risk	NOUN
gs-3921	635	15	of	of	ADP
gs-3921	635	16	adverse	adverse	ADJ
gs-3921	635	17	drug	drug	NOUN
gs-3921	635	18	reactions	reaction	NOUN
gs-3921	635	19	or	or	CCONJ
gs-3921	635	20	therapeutic	therapeutic	ADJ
gs-3921	635	21	failure	failure	NOUN
gs-3921	635	22	,	,	PUNCT
gs-3921	635	23	allowing	allow	VERB
gs-3921	635	24	for	for	ADP
gs-3921	635	25	proactive	proactive	ADJ
gs-3921	635	26	medication	medication	NOUN
gs-3921	635	27	selection	selection	NOUN
gs-3921	635	28	and	and	CCONJ
gs-3921	635	29	dosing	dosing	NOUN
gs-3921	635	30	.	.	PUNCT
gs-3921	636	1			VERB
gs-3921	636	2	expand	expand	VERB
gs-3921	636	3	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	636	4	education	education	NOUN
gs-3921	636	5	for	for	ADP
gs-3921	636	6	healthcare	healthcare	NOUN
gs-3921	636	7	providers	provider	NOUN
gs-3921	636	8	:	:	PUNCT
gs-3921	636	9	medical	medical	ADJ
gs-3921	636	10	,	,	PUNCT
gs-3921	636	11	pharmacy	pharmacy	NOUN
gs-3921	636	12	,	,	PUNCT
gs-3921	636	13	nursing	nursing	NOUN
gs-3921	636	14	,	,	PUNCT
gs-3921	636	15	and	and	CCONJ
gs-3921	636	16	allied	ally	VERB
gs-3921	636	17	health	health	NOUN
gs-3921	636	18	curricula	curricula	NOUN
gs-3921	636	19	must	must	AUX
gs-3921	636	20	be	be	AUX
gs-3921	636	21	updated	update	VERB
gs-3921	636	22	to	to	PART
gs-3921	636	23	include	include	VERB
gs-3921	636	24	core	core	NOUN
gs-3921	636	25	competencies	competency	NOUN
gs-3921	636	26	in	in	ADP
gs-3921	636	27	georgian	georgian	ADJ
gs-3921	636	28	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	636	29	მეცნიერები	მეცნიერები	NOUN
gs-3921	636	30	ტ.	ტ.	VERB
gs-3921	636	31	7	7	NUM
gs-3921	637	1	n	n	PRON
gs-3921	637	2	3	3	NUM
gs-3921	637	3	,	,	PUNCT
gs-3921	637	4	2025	2025	NUM
gs-3921	637	5	254	254	NUM
gs-3921	637	6	genomics	genomic	NOUN
gs-3921	637	7	,	,	PUNCT
gs-3921	637	8	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	637	9	,	,	PUNCT
gs-3921	637	10	and	and	CCONJ
gs-3921	637	11	personalized	personalized	ADJ
gs-3921	637	12	medicine	medicine	NOUN
gs-3921	637	13	.	.	PUNCT
gs-3921	638	1	continuous	continuous	ADJ
gs-3921	638	2	professional	professional	ADJ
gs-3921	638	3	development	development	NOUN
gs-3921	638	4	programs	program	NOUN
gs-3921	638	5	should	should	AUX
gs-3921	638	6	be	be	AUX
gs-3921	638	7	available	available	ADJ
gs-3921	638	8	to	to	ADP
gs-3921	638	9	practicing	practice	VERB
gs-3921	638	10	clinicians	clinician	NOUN
gs-3921	638	11	,	,	PUNCT
gs-3921	638	12	enabling	enable	VERB
gs-3921	638	13	them	they	PRON
gs-3921	638	14	to	to	PART
gs-3921	638	15	interpret	interpret	VERB
gs-3921	638	16	genetic	genetic	ADJ
gs-3921	638	17	data	datum	NOUN
gs-3921	638	18	,	,	PUNCT
gs-3921	638	19	communicate	communicate	VERB
gs-3921	638	20	effectively	effectively	ADV
gs-3921	638	21	with	with	ADP
gs-3921	638	22	patients	patient	NOUN
gs-3921	638	23	,	,	PUNCT
gs-3921	638	24	and	and	CCONJ
gs-3921	638	25	make	make	VERB
gs-3921	638	26	evidencebased	evidencebased	ADJ
gs-3921	638	27	therapeutic	therapeutic	ADJ
gs-3921	638	28	decisions	decision	NOUN
gs-3921	638	29	.	.	PUNCT
gs-3921	639	1			VERB
gs-3921	639	2	promote	promote	VERB
gs-3921	639	3	interdisciplinary	interdisciplinary	ADJ
gs-3921	639	4	collaboration	collaboration	NOUN
gs-3921	639	5	and	and	CCONJ
gs-3921	639	6	clinical	clinical	ADJ
gs-3921	639	7	decision	decision	NOUN
gs-3921	639	8	support	support	NOUN
gs-3921	639	9	:	:	PUNCT
gs-3921	639	10	effective	effective	ADJ
gs-3921	639	11	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	639	12	application	application	NOUN
gs-3921	639	13	demands	demand	NOUN
gs-3921	639	14	coordinated	coordinate	VERB
gs-3921	639	15	collaboration	collaboration	NOUN
gs-3921	639	16	among	among	ADP
gs-3921	639	17	clinicians	clinician	NOUN
gs-3921	639	18	,	,	PUNCT
gs-3921	639	19	clinical	clinical	ADJ
gs-3921	639	20	pharmacists	pharmacist	NOUN
gs-3921	639	21	,	,	PUNCT
gs-3921	639	22	genetic	genetic	ADJ
gs-3921	639	23	counselors	counselor	NOUN
gs-3921	639	24	,	,	PUNCT
gs-3921	639	25	bioinformaticians	bioinformatician	NOUN
gs-3921	639	26	,	,	PUNCT
gs-3921	639	27	and	and	CCONJ
gs-3921	639	28	health	health	NOUN
gs-3921	639	29	it	it	PRON
gs-3921	639	30	specialists	specialist	VERB
gs-3921	639	31	.	.	PUNCT
gs-3921	640	1	multidisciplinary	multidisciplinary	ADJ
gs-3921	640	2	teams	team	NOUN
gs-3921	640	3	should	should	AUX
gs-3921	640	4	be	be	AUX
gs-3921	640	5	supported	support	VERB
gs-3921	640	6	by	by	ADP
gs-3921	640	7	integrated	integrate	VERB
gs-3921	640	8	clinical	clinical	ADJ
gs-3921	640	9	decision	decision	NOUN
gs-3921	640	10	support	support	NOUN
gs-3921	640	11	systems	system	NOUN
gs-3921	640	12	that	that	PRON
gs-3921	640	13	provide	provide	VERB
gs-3921	640	14	real	real	ADJ
gs-3921	640	15	-	-	PUNCT
gs-3921	640	16	time	time	NOUN
gs-3921	640	17	,	,	PUNCT
gs-3921	640	18	patient	patient	NOUN
gs-3921	640	19	-	-	PUNCT
gs-3921	640	20	specific	specific	ADJ
gs-3921	640	21	recommendations	recommendation	NOUN
gs-3921	640	22	linked	link	VERB
gs-3921	640	23	to	to	ADP
gs-3921	640	24	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	640	25	test	test	NOUN
gs-3921	640	26	results	result	NOUN
gs-3921	640	27	within	within	ADP
gs-3921	640	28	electronic	electronic	ADJ
gs-3921	640	29	health	health	NOUN
gs-3921	640	30	records	record	NOUN
gs-3921	640	31	.	.	PUNCT
gs-3921	641	1			VERB
gs-3921	641	2	ensure	ensure	VERB
gs-3921	641	3	equitable	equitable	ADJ
gs-3921	641	4	access	access	NOUN
gs-3921	641	5	and	and	CCONJ
gs-3921	641	6	address	address	VERB
gs-3921	641	7	healthcare	healthcare	NOUN
gs-3921	641	8	disparities	disparity	NOUN
gs-3921	641	9	:	:	PUNCT
gs-3921	641	10	policy	policy	NOUN
gs-3921	641	11	makers	maker	NOUN
gs-3921	641	12	and	and	CCONJ
gs-3921	641	13	healthcare	healthcare	NOUN
gs-3921	641	14	leaders	leader	NOUN
gs-3921	641	15	should	should	AUX
gs-3921	641	16	actively	actively	ADV
gs-3921	641	17	work	work	VERB
gs-3921	641	18	to	to	PART
gs-3921	641	19	reduce	reduce	VERB
gs-3921	641	20	disparities	disparity	NOUN
gs-3921	641	21	in	in	ADP
gs-3921	641	22	access	access	NOUN
gs-3921	641	23	to	to	ADP
gs-3921	641	24	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	641	25	testing	testing	NOUN
gs-3921	641	26	and	and	CCONJ
gs-3921	641	27	personalized	personalized	ADJ
gs-3921	641	28	care	care	NOUN
gs-3921	641	29	services	service	NOUN
gs-3921	641	30	.	.	PUNCT
gs-3921	642	1	strategies	strategy	NOUN
gs-3921	642	2	include	include	VERB
gs-3921	642	3	subsidizing	subsidize	VERB
gs-3921	642	4	testing	testing	NOUN
gs-3921	642	5	in	in	ADP
gs-3921	642	6	underserved	underserved	ADJ
gs-3921	642	7	populations	population	NOUN
gs-3921	642	8	,	,	PUNCT
gs-3921	642	9	increasing	increase	VERB
gs-3921	642	10	geographic	geographic	ADJ
gs-3921	642	11	availability	availability	NOUN
gs-3921	642	12	through	through	ADP
gs-3921	642	13	telemedicine	telemedicine	NOUN
gs-3921	642	14	,	,	PUNCT
gs-3921	642	15	and	and	CCONJ
gs-3921	642	16	incorporating	incorporate	VERB
gs-3921	642	17	culturally	culturally	ADV
gs-3921	642	18	competent	competent	ADJ
gs-3921	642	19	care	care	NOUN
gs-3921	642	20	models	model	NOUN
gs-3921	642	21	to	to	PART
gs-3921	642	22	promote	promote	VERB
gs-3921	642	23	inclusivity	inclusivity	NOUN
gs-3921	642	24	.	.	PUNCT
gs-3921	643	1			PROPN
gs-3921	643	2	embed	embed	VERB
gs-3921	643	3	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	643	4	data	datum	NOUN
gs-3921	643	5	in	in	ADP
gs-3921	643	6	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	643	7	frameworks	framework	NOUN
gs-3921	643	8	:	:	PUNCT
gs-3921	643	9	national	national	ADJ
gs-3921	643	10	and	and	CCONJ
gs-3921	643	11	institutional	institutional	ADJ
gs-3921	643	12	pharmacovigilance	pharmacovigilance	NOUN
gs-3921	643	13	systems	system	NOUN
gs-3921	643	14	should	should	AUX
gs-3921	643	15	incorporate	incorporate	VERB
gs-3921	643	16	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	643	17	information	information	NOUN
gs-3921	643	18	into	into	ADP
gs-3921	643	19	adverse	adverse	ADJ
gs-3921	643	20	drug	drug	NOUN
gs-3921	643	21	reaction	reaction	NOUN
gs-3921	643	22	reporting	reporting	NOUN
gs-3921	643	23	,	,	PUNCT
gs-3921	643	24	risk	risk	NOUN
gs-3921	643	25	signal	signal	NOUN
gs-3921	643	26	detection	detection	NOUN
gs-3921	643	27	,	,	PUNCT
gs-3921	643	28	and	and	CCONJ
gs-3921	643	29	patient	patient	ADJ
gs-3921	643	30	safety	safety	NOUN
gs-3921	643	31	monitoring	monitoring	NOUN
gs-3921	643	32	.	.	PUNCT
gs-3921	644	1	this	this	PRON
gs-3921	644	2	includes	include	VERB
gs-3921	644	3	leveraging	leverage	VERB
gs-3921	644	4	real	real	ADJ
gs-3921	644	5	-	-	PUNCT
gs-3921	644	6	world	world	NOUN
gs-3921	644	7	evidence	evidence	NOUN
gs-3921	644	8	,	,	PUNCT
gs-3921	644	9	patient	patient	NOUN
gs-3921	644	10	-	-	PUNCT
gs-3921	644	11	reported	report	VERB
gs-3921	644	12	outcomes	outcome	NOUN
gs-3921	644	13	,	,	PUNCT
gs-3921	644	14	and	and	CCONJ
gs-3921	644	15	machine	machine	NOUN
gs-3921	644	16	learning	learn	VERB
gs-3921	644	17	approaches	approach	NOUN
gs-3921	644	18	to	to	PART
gs-3921	644	19	enhance	enhance	VERB
gs-3921	644	20	surveillance	surveillance	NOUN
gs-3921	644	21	of	of	ADP
gs-3921	644	22	genetically	genetically	ADV
gs-3921	644	23	mediated	mediate	VERB
gs-3921	644	24	adverse	adverse	ADJ
gs-3921	644	25	events	event	NOUN
gs-3921	644	26	.	.	PUNCT
gs-3921	645	1			ADJ
gs-3921	645	2	invest	inv	ADJ
gs-3921	645	3	in	in	ADP
gs-3921	645	4	multi	multi	ADJ
gs-3921	645	5	-	-	ADJ
gs-3921	645	6	omic	omic	ADJ
gs-3921	645	7	and	and	CCONJ
gs-3921	645	8	translational	translational	ADJ
gs-3921	645	9	research	research	NOUN
gs-3921	645	10	:	:	PUNCT
gs-3921	645	11	further	further	ADJ
gs-3921	645	12	research	research	NOUN
gs-3921	645	13	is	be	AUX
gs-3921	645	14	needed	need	VERB
gs-3921	645	15	to	to	PART
gs-3921	645	16	integrate	integrate	VERB
gs-3921	645	17	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	645	18	with	with	ADP
gs-3921	645	19	other	other	ADJ
gs-3921	645	20	“	"	PUNCT
gs-3921	645	21	-omics	-omic	NOUN
gs-3921	645	22	”	"	PUNCT
gs-3921	645	23	data	datum	NOUN
gs-3921	645	24	(	(	PUNCT
gs-3921	645	25	epigenomics	epigenomic	NOUN
gs-3921	645	26	,	,	PUNCT
gs-3921	645	27	proteomics	proteomic	NOUN
gs-3921	645	28	,	,	PUNCT
gs-3921	645	29	and	and	CCONJ
gs-3921	645	30	metabolomics	metabolomic	NOUN
gs-3921	645	31	)	)	PUNCT
gs-3921	645	32	to	to	PART
gs-3921	645	33	uncover	uncover	VERB
gs-3921	645	34	complex	complex	ADJ
gs-3921	645	35	biological	biological	ADJ
gs-3921	645	36	mechanisms	mechanism	NOUN
gs-3921	645	37	influencing	influence	VERB
gs-3921	645	38	drug	drug	NOUN
gs-3921	645	39	response	response	NOUN
gs-3921	645	40	and	and	CCONJ
gs-3921	645	41	toxicity	toxicity	NOUN
gs-3921	645	42	.	.	PUNCT
gs-3921	646	1	public	public	ADJ
gs-3921	646	2	and	and	CCONJ
gs-3921	646	3	private	private	ADJ
gs-3921	646	4	funding	funding	NOUN
gs-3921	646	5	agencies	agency	NOUN
gs-3921	646	6	should	should	AUX
gs-3921	646	7	prioritize	prioritize	VERB
gs-3921	646	8	longitudinal	longitudinal	ADJ
gs-3921	646	9	,	,	PUNCT
gs-3921	646	10	multiethnic	multiethnic	ADJ
gs-3921	646	11	,	,	PUNCT
gs-3921	646	12	and	and	CCONJ
gs-3921	646	13	translational	translational	ADJ
gs-3921	646	14	studies	study	NOUN
gs-3921	646	15	that	that	PRON
gs-3921	646	16	generate	generate	VERB
gs-3921	646	17	actionable	actionable	ADJ
gs-3921	646	18	knowledge	knowledge	NOUN
gs-3921	646	19	for	for	ADP
gs-3921	646	20	clinical	clinical	ADJ
gs-3921	646	21	use	use	NOUN
gs-3921	646	22	.	.	PUNCT
gs-3921	647	1			VERB
gs-3921	647	2	develop	develop	VERB
gs-3921	647	3	robust	robust	ADJ
gs-3921	647	4	ethical	ethical	ADJ
gs-3921	647	5	and	and	CCONJ
gs-3921	647	6	legal	legal	ADJ
gs-3921	647	7	safeguards	safeguard	NOUN
gs-3921	647	8	:	:	PUNCT
gs-3921	647	9	governments	government	NOUN
gs-3921	647	10	and	and	CCONJ
gs-3921	647	11	regulatory	regulatory	ADJ
gs-3921	647	12	authorities	authority	NOUN
gs-3921	647	13	should	should	AUX
gs-3921	647	14	establish	establish	VERB
gs-3921	647	15	comprehensive	comprehensive	ADJ
gs-3921	647	16	policies	policy	NOUN
gs-3921	647	17	to	to	PART
gs-3921	647	18	protect	protect	VERB
gs-3921	647	19	genetic	genetic	ADJ
gs-3921	647	20	data	datum	NOUN
gs-3921	647	21	privacy	privacy	NOUN
gs-3921	647	22	,	,	PUNCT
gs-3921	647	23	prevent	prevent	VERB
gs-3921	647	24	discrimination	discrimination	NOUN
gs-3921	647	25	,	,	PUNCT
gs-3921	647	26	and	and	CCONJ
gs-3921	647	27	ensure	ensure	VERB
gs-3921	647	28	informed	informed	ADJ
gs-3921	647	29	consent	consent	NOUN
gs-3921	647	30	.	.	PUNCT
gs-3921	648	1	ethical	ethical	ADJ
gs-3921	648	2	guidelines	guideline	NOUN
gs-3921	648	3	should	should	AUX
gs-3921	648	4	address	address	VERB
gs-3921	648	5	incidental	incidental	ADJ
gs-3921	648	6	findings	finding	NOUN
gs-3921	648	7	,	,	PUNCT
gs-3921	648	8	secondary	secondary	ADJ
gs-3921	648	9	use	use	NOUN
gs-3921	648	10	of	of	ADP
gs-3921	648	11	data	datum	NOUN
gs-3921	648	12	,	,	PUNCT
gs-3921	648	13	and	and	CCONJ
gs-3921	648	14	patient	patient	ADJ
gs-3921	648	15	autonomy	autonomy	NOUN
gs-3921	648	16	,	,	PUNCT
gs-3921	648	17	fostering	foster	VERB
gs-3921	648	18	public	public	ADJ
gs-3921	648	19	trust	trust	NOUN
gs-3921	648	20	and	and	CCONJ
gs-3921	648	21	responsible	responsible	ADJ
gs-3921	648	22	data	datum	NOUN
gs-3921	648	23	stewardship	stewardship	NOUN
gs-3921	648	24	.	.	PUNCT
gs-3921	649	1			VERB
gs-3921	649	2	standardize	standardize	PROPN
gs-3921	649	3	testing	testing	NOUN
gs-3921	649	4	,	,	PUNCT
gs-3921	649	5	guidelines	guideline	NOUN
gs-3921	649	6	,	,	PUNCT
gs-3921	649	7	and	and	CCONJ
gs-3921	649	8	regulatory	regulatory	ADJ
gs-3921	649	9	oversight	oversight	NOUN
gs-3921	649	10	:	:	PUNCT
gs-3921	649	11	harmonized	harmonized	ADJ
gs-3921	649	12	standards	standard	NOUN
gs-3921	649	13	for	for	ADP
gs-3921	649	14	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	649	15	test	test	NOUN
gs-3921	649	16	quality	quality	NOUN
gs-3921	649	17	,	,	PUNCT
gs-3921	649	18	interpretation	interpretation	NOUN
gs-3921	649	19	,	,	PUNCT
gs-3921	649	20	and	and	CCONJ
gs-3921	649	21	clinical	clinical	ADJ
gs-3921	649	22	application	application	NOUN
gs-3921	649	23	are	be	AUX
gs-3921	649	24	essential	essential	ADJ
gs-3921	649	25	.	.	PUNCT
gs-3921	650	1	national	national	ADJ
gs-3921	650	2	and	and	CCONJ
gs-3921	650	3	international	international	ADJ
gs-3921	650	4	regulatory	regulatory	ADJ
gs-3921	650	5	bodies	body	NOUN
gs-3921	650	6	should	should	AUX
gs-3921	650	7	collaborate	collaborate	VERB
gs-3921	650	8	to	to	PART
gs-3921	650	9	align	align	VERB
gs-3921	650	10	guidelines	guideline	NOUN
gs-3921	650	11	,	,	PUNCT
gs-3921	650	12	facilitate	facilitate	NOUN
gs-3921	650	13	test	test	NOUN
gs-3921	650	14	approvals	approval	NOUN
gs-3921	650	15	,	,	PUNCT
gs-3921	650	16	and	and	CCONJ
gs-3921	650	17	ensure	ensure	VERB
gs-3921	650	18	consistent	consistent	ADJ
gs-3921	650	19	,	,	PUNCT
gs-3921	650	20	evidence	evidence	NOUN
gs-3921	650	21	-	-	PUNCT
gs-3921	650	22	based	base	VERB
gs-3921	650	23	implementation	implementation	NOUN
gs-3921	650	24	across	across	ADP
gs-3921	650	25	healthcare	healthcare	NOUN
gs-3921	650	26	settings	setting	NOUN
gs-3921	650	27	.	.	PUNCT
gs-3921	651	1			VERB
gs-3921	651	2	advance	advance	NOUN
gs-3921	651	3	patient	patient	ADJ
gs-3921	651	4	education	education	NOUN
gs-3921	651	5	and	and	CCONJ
gs-3921	651	6	engagement	engagement	NOUN
gs-3921	651	7	:	:	PUNCT
gs-3921	651	8	patients	patient	NOUN
gs-3921	651	9	should	should	AUX
gs-3921	651	10	be	be	AUX
gs-3921	651	11	empowered	empower	VERB
gs-3921	651	12	through	through	ADP
gs-3921	651	13	accessible	accessible	ADJ
gs-3921	651	14	,	,	PUNCT
gs-3921	651	15	evidence	evidence	NOUN
gs-3921	651	16	-	-	PUNCT
gs-3921	651	17	based	base	VERB
gs-3921	651	18	educational	educational	ADJ
gs-3921	651	19	resources	resource	NOUN
gs-3921	651	20	that	that	PRON
gs-3921	651	21	explain	explain	VERB
gs-3921	651	22	the	the	DET
gs-3921	651	23	role	role	NOUN
gs-3921	651	24	of	of	ADP
gs-3921	651	25	genetics	genetic	NOUN
gs-3921	651	26	in	in	ADP
gs-3921	651	27	georgian	georgian	ADJ
gs-3921	651	28	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	651	29	მეცნიერები	მეცნიერები	NOUN
gs-3921	651	30	ტ.	ტ.	VERB
gs-3921	651	31	7	7	NUM
gs-3921	651	32	n	n	PRON
gs-3921	651	33	3	3	NUM
gs-3921	651	34	,	,	PUNCT
gs-3921	651	35	2025	2025	NUM
gs-3921	651	36	255	255	NUM
gs-3921	651	37	drug	drug	NOUN
gs-3921	651	38	response	response	NOUN
gs-3921	651	39	and	and	CCONJ
gs-3921	651	40	the	the	DET
gs-3921	651	41	value	value	NOUN
gs-3921	651	42	of	of	ADP
gs-3921	651	43	personalized	personalized	ADJ
gs-3921	651	44	medicine	medicine	NOUN
gs-3921	651	45	.	.	PUNCT
gs-3921	652	1	healthcare	healthcare	NOUN
gs-3921	652	2	providers	provider	NOUN
gs-3921	652	3	must	must	AUX
gs-3921	652	4	engage	engage	VERB
gs-3921	652	5	patients	patient	NOUN
gs-3921	652	6	in	in	ADP
gs-3921	652	7	shared	shared	ADJ
gs-3921	652	8	decision	decision	NOUN
gs-3921	652	9	-	-	PUNCT
gs-3921	652	10	making	making	NOUN
gs-3921	652	11	,	,	PUNCT
gs-3921	652	12	respecting	respect	VERB
gs-3921	652	13	individual	individual	ADJ
gs-3921	652	14	values	value	NOUN
gs-3921	652	15	,	,	PUNCT
gs-3921	652	16	preferences	preference	NOUN
gs-3921	652	17	,	,	PUNCT
gs-3921	652	18	and	and	CCONJ
gs-3921	652	19	health	health	NOUN
gs-3921	652	20	literacy	literacy	NOUN
gs-3921	652	21	levels	level	NOUN
gs-3921	652	22	.	.	PUNCT
gs-3921	653	1			VERB
gs-3921	653	2	encourage	encourage	VERB
gs-3921	653	3	cost	cost	NOUN
gs-3921	653	4	-	-	PUNCT
gs-3921	653	5	effectiveness	effectiveness	NOUN
gs-3921	653	6	analyses	analysis	NOUN
gs-3921	653	7	and	and	CCONJ
gs-3921	653	8	value	value	NOUN
gs-3921	653	9	-	-	PUNCT
gs-3921	653	10	based	base	VERB
gs-3921	653	11	models	model	NOUN
gs-3921	653	12	:	:	PUNCT
gs-3921	653	13	health	health	NOUN
gs-3921	653	14	economists	economist	NOUN
gs-3921	653	15	and	and	CCONJ
gs-3921	653	16	policy	policy	NOUN
gs-3921	653	17	developers	developer	NOUN
gs-3921	653	18	should	should	AUX
gs-3921	653	19	conduct	conduct	VERB
gs-3921	653	20	rigorous	rigorous	ADJ
gs-3921	653	21	cost	cost	NOUN
gs-3921	653	22	-	-	PUNCT
gs-3921	653	23	effectiveness	effectiveness	NOUN
gs-3921	653	24	analyses	analysis	NOUN
gs-3921	653	25	of	of	ADP
gs-3921	653	26	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	653	27	-	-	PUNCT
gs-3921	653	28	guided	guide	VERB
gs-3921	653	29	therapy	therapy	NOUN
gs-3921	653	30	.	.	PUNCT
gs-3921	654	1	evidence	evidence	NOUN
gs-3921	654	2	generated	generate	VERB
gs-3921	654	3	should	should	AUX
gs-3921	654	4	inform	inform	VERB
gs-3921	654	5	payer	payer	NOUN
gs-3921	654	6	policies	policy	NOUN
gs-3921	654	7	and	and	CCONJ
gs-3921	654	8	support	support	VERB
gs-3921	654	9	the	the	DET
gs-3921	654	10	development	development	NOUN
gs-3921	654	11	of	of	ADP
gs-3921	654	12	value	value	NOUN
gs-3921	654	13	-	-	PUNCT
gs-3921	654	14	based	base	VERB
gs-3921	654	15	care	care	NOUN
gs-3921	654	16	models	model	NOUN
gs-3921	654	17	that	that	PRON
gs-3921	654	18	incentivize	incentivize	VERB
gs-3921	654	19	outcomes	outcome	NOUN
gs-3921	654	20	-	-	PUNCT
gs-3921	654	21	driven	drive	VERB
gs-3921	654	22	implementation	implementation	NOUN
gs-3921	654	23	of	of	ADP
gs-3921	654	24	personalized	personalized	ADJ
gs-3921	654	25	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	654	26	.	.	PUNCT
gs-3921	655	1			VERB
gs-3921	655	2	foster	foster	ADJ
gs-3921	655	3	global	global	ADJ
gs-3921	655	4	collaboration	collaboration	NOUN
gs-3921	655	5	and	and	CCONJ
gs-3921	655	6	data	datum	NOUN
gs-3921	655	7	sharing	sharing	NOUN
gs-3921	655	8	:	:	PUNCT
gs-3921	655	9	to	to	PART
gs-3921	655	10	maximize	maximize	VERB
gs-3921	655	11	the	the	DET
gs-3921	655	12	benefits	benefit	NOUN
gs-3921	655	13	of	of	ADP
gs-3921	655	14	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	655	15	,	,	PUNCT
gs-3921	655	16	global	global	ADJ
gs-3921	655	17	networks	network	NOUN
gs-3921	655	18	should	should	AUX
gs-3921	655	19	be	be	AUX
gs-3921	655	20	established	establish	VERB
gs-3921	655	21	to	to	PART
gs-3921	655	22	promote	promote	VERB
gs-3921	655	23	knowledge	knowledge	NOUN
gs-3921	655	24	exchange	exchange	NOUN
gs-3921	655	25	,	,	PUNCT
gs-3921	655	26	data	datum	NOUN
gs-3921	655	27	sharing	sharing	NOUN
gs-3921	655	28	,	,	PUNCT
gs-3921	655	29	and	and	CCONJ
gs-3921	655	30	capacity	capacity	NOUN
gs-3921	655	31	building	building	NOUN
gs-3921	655	32	.	.	PUNCT
gs-3921	656	1	such	such	ADJ
gs-3921	656	2	efforts	effort	NOUN
gs-3921	656	3	can	can	AUX
gs-3921	656	4	accelerate	accelerate	VERB
gs-3921	656	5	research	research	NOUN
gs-3921	656	6	,	,	PUNCT
gs-3921	656	7	enable	enable	VERB
gs-3921	656	8	access	access	NOUN
gs-3921	656	9	to	to	ADP
gs-3921	656	10	testing	testing	NOUN
gs-3921	656	11	in	in	ADP
gs-3921	656	12	resource	resource	NOUN
gs-3921	656	13	-	-	PUNCT
gs-3921	656	14	limited	limit	VERB
gs-3921	656	15	settings	setting	NOUN
gs-3921	656	16	,	,	PUNCT
gs-3921	656	17	and	and	CCONJ
gs-3921	656	18	advance	advance	VERB
gs-3921	656	19	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	656	20	applications	application	NOUN
gs-3921	656	21	in	in	ADP
gs-3921	656	22	global	global	ADJ
gs-3921	656	23	public	public	ADJ
gs-3921	656	24	health	health	NOUN
gs-3921	656	25	.	.	PUNCT
gs-3921	657	1	references	reference	NOUN
gs-3921	657	2	1	1	NUM
gs-3921	657	3	.	.	PUNCT
gs-3921	658	1	dunnenberger	dunnenberger	NOUN
gs-3921	658	2	,	,	PUNCT
gs-3921	658	3	heather	heather	PROPN
gs-3921	658	4	m.	m.	NOUN
gs-3921	658	5	,	,	PUNCT
gs-3921	658	6	kristin	kristin	PROPN
gs-3921	658	7	w.	w.	PROPN
gs-3921	658	8	crews	crews	PROPN
gs-3921	658	9	,	,	PUNCT
gs-3921	658	10	kristine	kristine	PROPN
gs-3921	658	11	r.	r.	PROPN
gs-3921	658	12	hoffman	hoffman	PROPN
gs-3921	658	13	,	,	PUNCT
gs-3921	658	14	et	et	PROPN
gs-3921	658	15	al	al	PROPN
gs-3921	658	16	.	.	PROPN
gs-3921	658	17	2014	2014	NUM
gs-3921	658	18	.	.	PUNCT
gs-3921	659	1	“	"	PUNCT
gs-3921	659	2	preemptive	preemptive	ADJ
gs-3921	659	3	clinical	clinical	ADJ
gs-3921	659	4	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	659	5	implementation	implementation	NOUN
gs-3921	659	6	:	:	PUNCT
gs-3921	659	7	current	current	ADJ
gs-3921	659	8	programs	program	NOUN
gs-3921	659	9	in	in	ADP
gs-3921	659	10	five	five	NUM
gs-3921	659	11	us	us	PROPN
gs-3921	659	12	medical	medical	ADJ
gs-3921	659	13	centers	center	NOUN
gs-3921	659	14	.	.	PUNCT
gs-3921	659	15	”	"	PUNCT
gs-3921	660	1	annual	annual	ADJ
gs-3921	660	2	review	review	NOUN
gs-3921	660	3	of	of	ADP
gs-3921	660	4	pharmacology	pharmacology	NOUN
gs-3921	660	5	and	and	CCONJ
gs-3921	660	6	toxicology	toxicology	NOUN
gs-3921	660	7	54	54	NUM
gs-3921	660	8	:	:	PUNCT
gs-3921	660	9	413–31	413–31	NUM
gs-3921	660	10	.	.	PROPN
gs-3921	661	1	2	2	X
gs-3921	661	2	.	.	X
gs-3921	661	3	phillips	phillips	PROPN
gs-3921	661	4	,	,	PUNCT
gs-3921	661	5	kathryn	kathryn	PROPN
gs-3921	661	6	a.	a.	PROPN
gs-3921	661	7	,	,	PUNCT
gs-3921	661	8	devin	devin	PROPN
gs-3921	661	9	incerti	incerti	PROPN
gs-3921	661	10	,	,	PUNCT
gs-3921	661	11	and	and	CCONJ
gs-3921	661	12	kathryn	kathryn	PROPN
gs-3921	661	13	veenstra	veenstra	PROPN
gs-3921	661	14	.	.	PROPN
gs-3921	661	15	2017	2017	NUM
gs-3921	661	16	.	.	PUNCT
gs-3921	662	1	“	"	PUNCT
gs-3921	662	2	gene	gene	NOUN
gs-3921	662	3	-	-	PUNCT
gs-3921	662	4	specific	specific	ADJ
gs-3921	662	5	personalized	personalized	ADJ
gs-3921	662	6	medicine	medicine	NOUN
gs-3921	662	7	:	:	PUNCT
gs-3921	662	8	insights	insight	NOUN
gs-3921	662	9	from	from	ADP
gs-3921	662	10	examples	example	NOUN
gs-3921	662	11	focusing	focus	VERB
gs-3921	662	12	on	on	ADP
gs-3921	662	13	cost	cost	NOUN
gs-3921	662	14	-	-	PUNCT
gs-3921	662	15	effectiveness	effectiveness	NOUN
gs-3921	662	16	.	.	PUNCT
gs-3921	662	17	”	"	PUNCT
gs-3921	663	1	value	value	NOUN
gs-3921	663	2	in	in	ADP
gs-3921	663	3	health	health	NOUN
gs-3921	663	4	20	20	NUM
gs-3921	663	5	(	(	PUNCT
gs-3921	663	6	2	2	NUM
gs-3921	663	7	):	):	PUNCT
gs-3921	663	8	179–85	179–85	NUM
gs-3921	663	9	.	.	PUNCT
gs-3921	664	1	3	3	X
gs-3921	664	2	.	.	X
gs-3921	664	3	roden	roden	PROPN
gs-3921	664	4	,	,	PUNCT
gs-3921	664	5	dan	dan	PROPN
gs-3921	664	6	m.	m.	PROPN
gs-3921	664	7	,	,	PUNCT
gs-3921	664	8	and	and	CCONJ
gs-3921	664	9	josh	josh	PROPN
gs-3921	664	10	f.	f.	PROPN
gs-3921	664	11	peterson	peterson	PROPN
gs-3921	664	12	.	.	PROPN
gs-3921	664	13	2019	2019	NUM
gs-3921	664	14	.	.	PUNCT
gs-3921	665	1	“	"	PUNCT
gs-3921	665	2	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	665	3	:	:	PUNCT
gs-3921	665	4	challenges	challenge	NOUN
gs-3921	665	5	and	and	CCONJ
gs-3921	665	6	opportunities	opportunity	NOUN
gs-3921	665	7	.	.	PUNCT
gs-3921	665	8	”	"	PUNCT
gs-3921	665	9	annals	annal	NOUN
gs-3921	665	10	of	of	ADP
gs-3921	665	11	internal	internal	ADJ
gs-3921	665	12	medicine	medicine	NOUN
gs-3921	665	13	170	170	NUM
gs-3921	665	14	(	(	PUNCT
gs-3921	665	15	5	5	NUM
gs-3921	665	16	):	):	PUNCT
gs-3921	665	17	333–36	333–36	NUM
gs-3921	665	18	.	.	PUNCT
gs-3921	666	1	4	4	NUM
gs-3921	666	2	.	.	X
gs-3921	666	3	haga	haga	NOUN
gs-3921	666	4	,	,	PUNCT
gs-3921	666	5	susanne	susanne	PROPN
gs-3921	666	6	b.	b.	PROPN
gs-3921	666	7	,	,	PUNCT
gs-3921	666	8	jivan	jivan	PROPN
gs-3921	666	9	moaddeb	moaddeb	ADV
gs-3921	666	10	,	,	PUNCT
gs-3921	666	11	and	and	CCONJ
gs-3921	666	12	geoffrey	geoffrey	PROPN
gs-3921	666	13	s.	s.	PROPN
gs-3921	666	14	ginsburg	ginsburg	PROPN
gs-3921	666	15	.	.	PUNCT
gs-3921	666	16	2014	2014	NUM
gs-3921	666	17	.	.	PUNCT
gs-3921	667	1	“	"	PUNCT
gs-3921	667	2	adoption	adoption	NOUN
gs-3921	667	3	of	of	ADP
gs-3921	667	4	clinical	clinical	ADJ
gs-3921	667	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	667	6	:	:	PUNCT
gs-3921	667	7	barriers	barrier	NOUN
gs-3921	667	8	and	and	CCONJ
gs-3921	667	9	solutions	solution	NOUN
gs-3921	667	10	.	.	PUNCT
gs-3921	667	11	”	"	PUNCT
gs-3921	668	1	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	668	2	and	and	CCONJ
gs-3921	668	3	personalized	personalized	ADJ
gs-3921	668	4	medicine	medicine	NOUN
gs-3921	668	5	7	7	NUM
gs-3921	668	6	:	:	PUNCT
gs-3921	668	7	115–26	115–26	NUM
gs-3921	668	8	.	.	NOUN
gs-3921	668	9	5	5	NUM
gs-3921	668	10	.	.	X
gs-3921	668	11	swen	swen	PROPN
gs-3921	668	12	,	,	PUNCT
gs-3921	668	13	jesse	jesse	PROPN
gs-3921	668	14	j.	j.	PROPN
gs-3921	668	15	,	,	PUNCT
gs-3921	668	16	henk	henk	PROPN
gs-3921	668	17	-	-	PUNCT
gs-3921	668	18	jan	jan	PROPN
gs-3921	668	19	guchelaar	guchelaar	NOUN
gs-3921	668	20	,	,	PUNCT
gs-3921	668	21	and	and	CCONJ
gs-3921	668	22	ron	ron	PROPN
gs-3921	668	23	h.	h.	PROPN
gs-3921	668	24	n.	n.	PROPN
gs-3921	668	25	van	van	PROPN
gs-3921	668	26	schaik	schaik	NOUN
gs-3921	668	27	.	.	PUNCT
gs-3921	668	28	2012	2012	NUM
gs-3921	668	29	.	.	PUNCT
gs-3921	669	1	“	"	PUNCT
gs-3921	669	2	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	669	3	:	:	PUNCT
gs-3921	669	4	from	from	ADP
gs-3921	669	5	bench	bench	NOUN
gs-3921	669	6	to	to	PART
gs-3921	669	7	byte	byte	VERB
gs-3921	669	8	.	.	PUNCT
gs-3921	669	9	”	"	PUNCT
gs-3921	670	1	clinical	clinical	ADJ
gs-3921	670	2	pharmacology	pharmacology	NOUN
gs-3921	670	3	&	&	CCONJ
gs-3921	670	4	therapeutics	therapeutic	NOUN
gs-3921	670	5	91	91	NUM
gs-3921	670	6	(	(	PUNCT
gs-3921	670	7	5	5	NUM
gs-3921	670	8	):	):	PUNCT
gs-3921	670	9	781–83	781–83	NUM
gs-3921	670	10	.	.	NOUN
gs-3921	670	11	6	6	NUM
gs-3921	670	12	.	.	X
gs-3921	671	1	pirmohamed	pirmohame	VERB
gs-3921	671	2	,	,	PUNCT
gs-3921	671	3	munir	munir	PROPN
gs-3921	671	4	.	.	PUNCT
gs-3921	672	1	2011	2011	NUM
gs-3921	672	2	.	.	PUNCT
gs-3921	673	1	“	"	PUNCT
gs-3921	673	2	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	673	3	and	and	CCONJ
gs-3921	673	4	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	673	5	.	.	PUNCT
gs-3921	673	6	”	"	PUNCT
gs-3921	674	1	british	british	ADJ
gs-3921	674	2	journal	journal	PROPN
gs-3921	674	3	of	of	ADP
gs-3921	674	4	clinical	clinical	ADJ
gs-3921	674	5	pharmacology	pharmacology	NOUN
gs-3921	674	6	52	52	NUM
gs-3921	674	7	(	(	PUNCT
gs-3921	674	8	4	4	NUM
gs-3921	674	9	):	):	PUNCT
gs-3921	674	10	345–47	345–47	NUM
gs-3921	674	11	.	.	X
gs-3921	674	12	7	7	X
gs-3921	674	13	.	.	X
gs-3921	674	14	amstutz	amstutz	PROPN
gs-3921	674	15	,	,	PUNCT
gs-3921	674	16	ute	ute	PROPN
gs-3921	674	17	,	,	PUNCT
gs-3921	674	18	and	and	CCONJ
gs-3921	674	19	matthias	matthias	PROPN
gs-3921	674	20	schwab	schwab	NOUN
gs-3921	674	21	.	.	PUNCT
gs-3921	675	1	2018	2018	NUM
gs-3921	675	2	.	.	PUNCT
gs-3921	676	1	“	"	PUNCT
gs-3921	676	2	clinical	clinical	ADJ
gs-3921	676	3	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	676	4	:	:	PUNCT
gs-3921	676	5	implementation	implementation	NOUN
gs-3921	676	6	and	and	CCONJ
gs-3921	676	7	challenges	challenge	NOUN
gs-3921	676	8	in	in	ADP
gs-3921	676	9	the	the	DET
gs-3921	676	10	real	real	ADJ
gs-3921	676	11	world	world	NOUN
gs-3921	676	12	.	.	PUNCT
gs-3921	676	13	”	"	PUNCT
gs-3921	677	1	annual	annual	ADJ
gs-3921	677	2	review	review	NOUN
gs-3921	677	3	of	of	ADP
gs-3921	677	4	pharmacology	pharmacology	NOUN
gs-3921	677	5	and	and	CCONJ
gs-3921	677	6	toxicology	toxicology	NOUN
gs-3921	677	7	58	58	NUM
gs-3921	677	8	:	:	PUNCT
gs-3921	677	9	377–94	377–94	NUM
gs-3921	677	10	.	.	X
gs-3921	677	11	8	8	NUM
gs-3921	677	12	.	.	X
gs-3921	677	13	caudle	caudle	PROPN
gs-3921	677	14	,	,	PUNCT
gs-3921	677	15	kelly	kelly	PROPN
gs-3921	677	16	e.	e.	PROPN
gs-3921	677	17	,	,	PUNCT
gs-3921	677	18	teri	teri	PROPN
gs-3921	677	19	e.	e.	PROPN
gs-3921	677	20	klein	klein	PROPN
gs-3921	677	21	,	,	PUNCT
gs-3921	677	22	mary	mary	PROPN
gs-3921	677	23	v.	v.	ADP
gs-3921	677	24	relling	relling	PROPN
gs-3921	677	25	,	,	PUNCT
gs-3921	677	26	et	et	PROPN
gs-3921	677	27	al	al	PROPN
gs-3921	677	28	.	.	PROPN
gs-3921	677	29	2014	2014	NUM
gs-3921	677	30	.	.	PUNCT
gs-3921	678	1	“	"	PUNCT
gs-3921	678	2	standardizing	standardize	VERB
gs-3921	678	3	terms	term	NOUN
gs-3921	678	4	for	for	ADP
gs-3921	678	5	clinical	clinical	ADJ
gs-3921	678	6	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	678	7	:	:	PUNCT
gs-3921	678	8	the	the	DET
gs-3921	678	9	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	678	10	clinical	clinical	ADJ
gs-3921	678	11	annotation	annotation	NOUN
gs-3921	678	12	tool	tool	NOUN
gs-3921	678	13	.	.	PUNCT
gs-3921	678	14	”	"	PUNCT
gs-3921	678	15	genetics	genetic	NOUN
gs-3921	678	16	in	in	ADP
gs-3921	678	17	medicine	medicine	NOUN
gs-3921	678	18	16	16	NUM
gs-3921	678	19	(	(	PUNCT
gs-3921	678	20	10	10	NUM
gs-3921	678	21	):	):	PUNCT
gs-3921	678	22	809–15	809–15	NUM
gs-3921	678	23	.	.	PUNCT
gs-3921	679	1	9	9	NUM
gs-3921	679	2	.	.	X
gs-3921	679	3	ryu	ryu	ADJ
gs-3921	679	4	,	,	PUNCT
gs-3921	679	5	jae	jae	PROPN
gs-3921	679	6	-	-	PUNCT
gs-3921	679	7	yoon	yoon	PROPN
gs-3921	679	8	,	,	PUNCT
gs-3921	679	9	soyoung	soyoung	NOUN
gs-3921	679	10	kim	kim	PROPN
gs-3921	679	11	,	,	PUNCT
gs-3921	679	12	and	and	CCONJ
gs-3921	679	13	byoung	byoung	ADJ
gs-3921	679	14	-	-	PUNCT
gs-3921	679	15	kie	kie	NOUN
gs-3921	679	16	kim	kim	PROPN
gs-3921	679	17	.	.	PROPN
gs-3921	679	18	2019	2019	NUM
gs-3921	679	19	.	.	PUNCT
gs-3921	680	1	“	"	PUNCT
gs-3921	680	2	integration	integration	NOUN
gs-3921	680	3	of	of	ADP
gs-3921	680	4	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	680	5	into	into	ADP
gs-3921	680	6	electronic	electronic	ADJ
gs-3921	680	7	health	health	NOUN
gs-3921	680	8	records	record	NOUN
gs-3921	680	9	for	for	ADP
gs-3921	680	10	personalized	personalized	ADJ
gs-3921	680	11	medicine	medicine	NOUN
gs-3921	680	12	.	.	PUNCT
gs-3921	680	13	”	"	PUNCT
gs-3921	681	1	journal	journal	NOUN
gs-3921	681	2	of	of	ADP
gs-3921	681	3	biomedical	biomedical	ADJ
gs-3921	681	4	informatics	informatic	NOUN
gs-3921	681	5	96	96	NUM
gs-3921	681	6	:	:	SYM
gs-3921	681	7	103245	103245	NUM
gs-3921	681	8	.	.	PUNCT
gs-3921	682	1	georgian	georgian	ADJ
gs-3921	682	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	682	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	682	4	ტ.	ტ.	VERB
gs-3921	682	5	7	7	NUM
gs-3921	682	6	n	n	DET
gs-3921	682	7	3	3	NUM
gs-3921	682	8	,	,	PUNCT
gs-3921	682	9	2025	2025	NUM
gs-3921	682	10	256	256	NUM
gs-3921	682	11	10	10	NUM
gs-3921	682	12	.	.	PUNCT
gs-3921	683	1	aphkhazava	aphkhazava	PROPN
gs-3921	683	2	,	,	PUNCT
gs-3921	683	3	d.	d.	PROPN
gs-3921	683	4	,	,	PUNCT
gs-3921	683	5	sulashvili	sulashvili	NOUN
gs-3921	683	6	,	,	PUNCT
gs-3921	683	7	n.	n.	NOUN
gs-3921	683	8	,	,	PUNCT
gs-3921	683	9	tupinashvili	tupinashvili	NOUN
gs-3921	683	10	,	,	PUNCT
gs-3921	683	11	t.	t.	PROPN
gs-3921	683	12	,	,	PUNCT
gs-3921	683	13	&	&	CCONJ
gs-3921	683	14	nozadze	nozadze	NOUN
gs-3921	683	15	,	,	PUNCT
gs-3921	683	16	m.	m.	NOUN
gs-3921	683	17	(	(	PUNCT
gs-3921	683	18	2024	2024	NUM
gs-3921	683	19	)	)	PUNCT
gs-3921	683	20	.	.	PUNCT
gs-3921	684	1	dynamic	dynamic	ADJ
gs-3921	684	2	cellular	cellular	ADJ
gs-3921	684	3	equilibrium	equilibrium	NOUN
gs-3921	684	4	theory	theory	NOUN
gs-3921	684	5	of	of	ADP
gs-3921	684	6	aging	aging	NOUN
gs-3921	684	7	:	:	PUNCT
gs-3921	684	8	integrating	integrate	VERB
gs-3921	684	9	maintenance	maintenance	NOUN
gs-3921	684	10	and	and	CCONJ
gs-3921	684	11	accumulation	accumulation	NOUN
gs-3921	684	12	in	in	ADP
gs-3921	684	13	the	the	DET
gs-3921	684	14	aging	age	VERB
gs-3921	684	15	process	process	NOUN
gs-3921	684	16	.	.	PUNCT
gs-3921	685	1	scientific	scientific	ADJ
gs-3921	685	2	journal	journal	NOUN
gs-3921	685	3	„	„	PUNCT
gs-3921	685	4	spectri	spectri	NOUN
gs-3921	685	5	“	"	PUNCT
gs-3921	685	6	,	,	PUNCT
gs-3921	685	7	8(2	8(2	NUM
gs-3921	685	8	)	)	PUNCT
gs-3921	685	9	.	.	PUNCT
gs-3921	686	1	https://doi.org/10.52340/spectri.2023.08.02.03	https://doi.org/10.52340/spectri.2023.08.02.03	ADJ
gs-3921	686	2	11	11	NUM
gs-3921	686	3	.	.	PUNCT
gs-3921	687	1	sulashvili	sulashvili	PROPN
gs-3921	687	2	n	n	PROPN
gs-3921	687	3	,	,	PUNCT
gs-3921	687	4	jadhav	jadhav	PROPN
gs-3921	687	5	rd	rd	PROPN
gs-3921	687	6	,	,	PUNCT
gs-3921	687	7	beglaryan	beglaryan	PROPN
gs-3921	687	8	m	m	PROPN
gs-3921	687	9	,	,	PUNCT
gs-3921	687	10	gabunia	gabunia	NOUN
gs-3921	687	11	l	l	NOUN
gs-3921	687	12	,	,	PUNCT
gs-3921	687	13	gorgaslidze	gorgaslidze	ADJ
gs-3921	687	14	n	n	CCONJ
gs-3921	687	15	,	,	PUNCT
gs-3921	687	16	alavidze	alavidze	PROPN
gs-3921	687	17	n	n	CCONJ
gs-3921	687	18	,	,	PUNCT
gs-3921	687	19	et	et	PROPN
gs-3921	687	20	al	al	PROPN
gs-3921	687	21	.	.	PUNCT
gs-3921	688	1	the	the	DET
gs-3921	688	2	scientific	scientific	ADJ
gs-3921	688	3	discussion	discussion	NOUN
gs-3921	688	4	of	of	ADP
gs-3921	688	5	key	key	ADJ
gs-3921	688	6	issue	issue	NOUN
gs-3921	688	7	aspects	aspect	NOUN
gs-3921	688	8	of	of	ADP
gs-3921	688	9	immunopathogenesis	immunopathogenesis	NOUN
gs-3921	688	10	and	and	CCONJ
gs-3921	688	11	pharmacological	pharmacological	NOUN
gs-3921	688	12	properties	property	NOUN
gs-3921	688	13	and	and	CCONJ
gs-3921	688	14	profiles	profile	NOUN
gs-3921	688	15	in	in	ADP
gs-3921	688	16	relation	relation	NOUN
gs-3921	688	17	to	to	ADP
gs-3921	688	18	adverse	adverse	ADJ
gs-3921	688	19	drug	drug	NOUN
gs-3921	688	20	reactions	reaction	NOUN
gs-3921	688	21	challenges	challenge	NOUN
gs-3921	688	22	,	,	PUNCT
gs-3921	688	23	focus	focus	VERB
gs-3921	688	24	on	on	ADP
gs-3921	688	25	multidimensional	multidimensional	ADJ
gs-3921	688	26	drug	drug	NOUN
gs-3921	688	27	-	-	PUNCT
gs-3921	688	28	induced	induce	VERB
gs-3921	688	29	eosinophilia	eosinophilia	NOUN
gs-3921	688	30	and	and	CCONJ
gs-3921	688	31	systemic	systemic	ADJ
gs-3921	688	32	syndrome	syndrome	NOUN
gs-3921	688	33	.	.	PUNCT
gs-3921	689	1	gs	gs	X
gs-3921	690	1	[	[	X
gs-3921	690	2	internet	internet	NOUN
gs-3921	690	3	]	]	X
gs-3921	690	4	.	.	PUNCT
gs-3921	691	1	2025	2025	NUM
gs-3921	691	2	jul	jul	NOUN
gs-3921	691	3	.	.	PROPN
gs-3921	691	4	11	11	NUM
gs-3921	692	1	[	[	X
gs-3921	692	2	cited	cite	VERB
gs-3921	692	3	2025	2025	NUM
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gs-3921	692	5	.	.	PROPN
gs-3921	692	6	12	12	NUM
gs-3921	692	7	]	]	PUNCT
gs-3921	692	8	;	;	PUNCT
gs-3921	692	9	7(3):141	7(3):141	NUM
gs-3921	692	10	-	-	SYM
gs-3921	692	11	79	79	NUM
gs-3921	692	12	.	.	PUNCT
gs-3921	693	1	available	available	ADJ
gs-3921	693	2	from	from	ADP
gs-3921	693	3	:	:	PUNCT
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gs-3921	693	5	.	.	NOUN
gs-3921	693	6	12	12	NUM
gs-3921	693	7	.	.	PUNCT
gs-3921	694	1	sulashvili	sulashvili	PROPN
gs-3921	694	2	n	n	PROPN
gs-3921	694	3	,	,	PUNCT
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gs-3921	694	6	,	,	PUNCT
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gs-3921	694	8	-	-	PUNCT
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gs-3921	694	10	a	a	PRON
gs-3921	694	11	,	,	PUNCT
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gs-3921	694	16	n	n	CCONJ
gs-3921	694	17	,	,	PUNCT
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gs-3921	694	20	,	,	PUNCT
gs-3921	694	21	et	et	PROPN
gs-3921	694	22	al	al	PROPN
gs-3921	694	23	.	.	PROPN
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gs-3921	694	25	-	-	PUNCT
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gs-3921	694	27	cardiopulmonary	cardiopulmonary	ADJ
gs-3921	694	28	bypass	bypass	NOUN
gs-3921	694	29	systems	system	NOUN
gs-3921	694	30	with	with	ADP
gs-3921	694	31	real	real	ADJ
gs-3921	694	32	-	-	PUNCT
gs-3921	694	33	time	time	NOUN
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gs-3921	694	35	and	and	CCONJ
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gs-3921	694	38	:	:	PUNCT
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gs-3921	694	40	,	,	PUNCT
gs-3921	694	41	outcomes	outcome	NOUN
gs-3921	694	42	,	,	PUNCT
gs-3921	694	43	clinical	clinical	ADJ
gs-3921	694	44	impact	impact	NOUN
gs-3921	694	45	and	and	CCONJ
gs-3921	694	46	future	future	ADJ
gs-3921	694	47	directions	direction	NOUN
gs-3921	694	48	in	in	ADP
gs-3921	694	49	general	general	ADJ
gs-3921	694	50	.	.	PUNCT
gs-3921	695	1	gs	gs	PROPN
gs-3921	696	1	[	[	X
gs-3921	696	2	internet	internet	NOUN
gs-3921	696	3	]	]	PUNCT
gs-3921	696	4	.	.	PUNCT
gs-3921	697	1	2025	2025	NUM
gs-3921	697	2	may	may	AUX
gs-3921	697	3	30	30	NUM
gs-3921	697	4	[	[	NOUN
gs-3921	697	5	cited	cite	VERB
gs-3921	697	6	2025	2025	NUM
gs-3921	697	7	jul	jul	PROPN
gs-3921	697	8	.	.	PROPN
gs-3921	698	1	12];7(2):381	12];7(2):381	NUM
gs-3921	698	2	-	-	SYM
gs-3921	698	3	419	419	NUM
gs-3921	698	4	.	.	PUNCT
gs-3921	699	1	available	available	ADJ
gs-3921	699	2	from	from	ADP
gs-3921	699	3	:	:	PUNCT
gs-3921	699	4	https://journals.4science.ge/index.php/gs/article/view/3799	https://journals.4science.ge/index.php/gs/article/view/3799	PROPN
gs-3921	699	5	.	.	PROPN
gs-3921	700	1	13	13	NUM
gs-3921	700	2	.	.	PUNCT
gs-3921	701	1	nodar	nodar	PROPN
gs-3921	701	2	sulashvili	sulashvili	NOUN
gs-3921	701	3	,	,	PUNCT
gs-3921	701	4	rupali	rupali	VERB
gs-3921	701	5	digambar	digambar	PROPN
gs-3921	701	6	jadhav	jadhav	PROPN
gs-3921	701	7	,	,	PUNCT
gs-3921	701	8	margarita	margarita	PROPN
gs-3921	701	9	beglaryan	beglaryan	PROPN
gs-3921	701	10	,	,	PUNCT
gs-3921	701	11	nana	nana	PROPN
gs-3921	701	12	gorgaslidze	gorgaslidze	PROPN
gs-3921	701	13	,	,	PUNCT
gs-3921	701	14	luiza	luiza	PROPN
gs-3921	701	15	gabunia	gabunia	PROPN
gs-3921	701	16	,	,	PUNCT
gs-3921	701	17	nato	nato	PROPN
gs-3921	701	18	alavidze	alavidze	PROPN
gs-3921	701	19	,	,	PUNCT
gs-3921	701	20	natia	natia	PROPN
gs-3921	701	21	kvizhinadze	kvizhinadze	PROPN
gs-3921	701	22	,	,	PUNCT
gs-3921	701	23	marika	marika	PROPN
gs-3921	701	24	sulashvili	sulashvili	PROPN
gs-3921	701	25	,	,	PUNCT
gs-3921	701	26	lela	lela	PROPN
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gs-3921	701	28	,	,	PUNCT
gs-3921	701	29	and	and	CCONJ
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gs-3921	701	31	robakidze	robakidze	NOUN
gs-3921	701	32	.	.	PUNCT
gs-3921	702	1	2025	2025	NUM
gs-3921	702	2	.	.	PUNCT
gs-3921	703	1	“	"	PUNCT
gs-3921	703	2	the	the	DET
gs-3921	703	3	manifestation	manifestation	NOUN
gs-3921	703	4	of	of	ADP
gs-3921	703	5	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	703	6	and	and	CCONJ
gs-3921	703	7	clinical	clinical	ADJ
gs-3921	703	8	perspectives	perspective	NOUN
gs-3921	703	9	on	on	ADP
gs-3921	703	10	medication	medication	NOUN
gs-3921	703	11	-	-	PUNCT
gs-3921	703	12	associated	associate	VERB
gs-3921	703	13	eosinophilia	eosinophilia	NOUN
gs-3921	703	14	and	and	CCONJ
gs-3921	703	15	systemic	systemic	ADJ
gs-3921	703	16	symptoms	symptom	NOUN
gs-3921	703	17	(	(	PUNCT
gs-3921	703	18	dress	dress	NOUN
gs-3921	703	19	):	):	PUNCT
gs-3921	703	20	a	a	DET
gs-3921	703	21	comprehensive	comprehensive	ADJ
gs-3921	703	22	evaluation	evaluation	NOUN
gs-3921	703	23	of	of	ADP
gs-3921	703	24	implicated	implicated	ADJ
gs-3921	703	25	agents	agent	NOUN
gs-3921	703	26	,	,	PUNCT
gs-3921	703	27	risk	risk	NOUN
gs-3921	703	28	factors	factor	NOUN
gs-3921	703	29	,	,	PUNCT
gs-3921	703	30	and	and	CCONJ
gs-3921	703	31	treatment	treatment	NOUN
gs-3921	703	32	managements	management	NOUN
gs-3921	703	33	strategies	strategy	NOUN
gs-3921	703	34	in	in	ADP
gs-3921	703	35	general	general	ADJ
gs-3921	703	36	”	"	PUNCT
gs-3921	703	37	.	.	PUNCT
gs-3921	704	1	georgian	georgian	PROPN
gs-3921	704	2	scientists	scientist	NOUN
gs-3921	704	3	7	7	NUM
gs-3921	704	4	(	(	PUNCT
gs-3921	704	5	3):180	3):180	NUM
gs-3921	704	6	-	-	SYM
gs-3921	704	7	216	216	NUM
gs-3921	704	8	.	.	PUNCT
gs-3921	705	1	https://doi.org/10.52340/gs.2025.07.03.14	https://doi.org/10.52340/gs.2025.07.03.14	NOUN
gs-3921	705	2	.	.	PROPN
gs-3921	705	3	14	14	NUM
gs-3921	705	4	.	.	PUNCT
gs-3921	706	1	sulashvili	sulashvili	NOUN
gs-3921	706	2	,	,	PUNCT
gs-3921	706	3	nodar	nodar	ADV
gs-3921	706	4	,	,	PUNCT
gs-3921	706	5	lali	lali	PROPN
gs-3921	706	6	patsia	patsia	PROPN
gs-3921	706	7	,	,	PUNCT
gs-3921	706	8	awad	awad	PROPN
gs-3921	706	9	el	el	PROPN
gs-3921	706	10	-	-	PUNCT
gs-3921	706	11	hakeem	hakeem	PROPN
gs-3921	706	12	,	,	PUNCT
gs-3921	706	13	sk	sk	PROPN
gs-3921	706	14	ayaan	ayaan	PROPN
gs-3921	706	15	,	,	PUNCT
gs-3921	706	16	arian	arian	ADJ
gs-3921	706	17	hizomi	hizomi	NOUN
gs-3921	706	18	,	,	PUNCT
gs-3921	706	19	sajal	sajal	PROPN
gs-3921	706	20	agarwal	agarwal	PROPN
gs-3921	706	21	,	,	PUNCT
gs-3921	706	22	and	and	CCONJ
gs-3921	706	23	marika	marika	PROPN
gs-3921	706	24	sulashvili	sulashvili	PROPN
gs-3921	706	25	.	.	PUNCT
gs-3921	707	1	2025	2025	NUM
gs-3921	707	2	.	.	PUNCT
gs-3921	708	1	“	"	PUNCT
gs-3921	708	2	exploring	explore	VERB
gs-3921	708	3	the	the	DET
gs-3921	708	4	gut	gut	NOUN
gs-3921	708	5	-	-	PUNCT
gs-3921	708	6	brain	brain	NOUN
gs-3921	708	7	axis	axis	NOUN
gs-3921	708	8	:	:	PUNCT
gs-3921	708	9	the	the	DET
gs-3921	708	10	role	role	NOUN
gs-3921	708	11	of	of	ADP
gs-3921	708	12	the	the	DET
gs-3921	708	13	microbiome	microbiome	NOUN
gs-3921	708	14	in	in	ADP
gs-3921	708	15	modulating	modulate	VERB
gs-3921	708	16	brain	brain	NOUN
gs-3921	708	17	function	function	NOUN
gs-3921	708	18	and	and	CCONJ
gs-3921	708	19	its	its	PRON
gs-3921	708	20	implications	implication	NOUN
gs-3921	708	21	in	in	ADP
gs-3921	708	22	neurodegenerative	neurodegenerative	ADJ
gs-3921	708	23	disorders	disorder	NOUN
gs-3921	708	24	like	like	ADP
gs-3921	708	25	parkinson	parkinson	NOUN
gs-3921	708	26	’s	’s	PART
gs-3921	708	27	and	and	CCONJ
gs-3921	708	28	alzheimer	alzheimer	PROPN
gs-3921	708	29	’s	’s	PART
gs-3921	708	30	and	and	CCONJ
gs-3921	708	31	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	708	32	treatment	treatment	NOUN
gs-3921	708	33	strategies	strategy	NOUN
gs-3921	708	34	”	"	PUNCT
gs-3921	708	35	.	.	PUNCT
gs-3921	709	1	georgian	georgian	PROPN
gs-3921	709	2	scientists	scientist	NOUN
gs-3921	709	3	7	7	NUM
gs-3921	709	4	(	(	PUNCT
gs-3921	709	5	2):329	2):329	NUM
gs-3921	709	6	-	-	SYM
gs-3921	709	7	53	53	NUM
gs-3921	709	8	.	.	PUNCT
gs-3921	710	1	https://doi.org/10.52340/gs.2025.07.02.32	https://doi.org/10.52340/gs.2025.07.02.32	PROPN
gs-3921	710	2	.	.	PROPN
gs-3921	710	3	15	15	NUM
gs-3921	710	4	.	.	PUNCT
gs-3921	711	1	sulashvili	sulashvili	NOUN
gs-3921	711	2	,	,	PUNCT
gs-3921	711	3	n.	n.	NOUN
gs-3921	711	4	,	,	PUNCT
gs-3921	711	5	gorgaslidze	gorgaslidze	PROPN
gs-3921	711	6	,	,	PUNCT
gs-3921	711	7	n.	n.	NOUN
gs-3921	711	8	,	,	PUNCT
gs-3921	711	9	gabunia	gabunia	NOUN
gs-3921	711	10	,	,	PUNCT
gs-3921	711	11	l.	l.	PROPN
gs-3921	711	12	,	,	PUNCT
gs-3921	711	13	giorgobiani	giorgobiani	PROPN
gs-3921	711	14	,	,	PUNCT
gs-3921	711	15	m.	m.	NOUN
gs-3921	711	16	,	,	PUNCT
gs-3921	711	17	&	&	CCONJ
gs-3921	711	18	ratiani	ratiani	PROPN
gs-3921	711	19	,	,	PUNCT
gs-3921	711	20	l.	l.	PROPN
gs-3921	711	21	(	(	PUNCT
gs-3921	711	22	2023	2023	NUM
gs-3921	711	23	)	)	PUNCT
gs-3921	711	24	.	.	PUNCT
gs-3921	712	1	manifestation	manifestation	NOUN
gs-3921	712	2	of	of	ADP
gs-3921	712	3	the	the	DET
gs-3921	712	4	particularities	particularity	NOUN
gs-3921	712	5	of	of	ADP
gs-3921	712	6	the	the	DET
gs-3921	712	7	usage	usage	NOUN
gs-3921	712	8	features	feature	NOUN
gs-3921	712	9	of	of	ADP
gs-3921	712	10	monoclonal	monoclonal	NOUN
gs-3921	712	11	antibodies	antibody	NOUN
gs-3921	712	12	in	in	ADP
gs-3921	712	13	various	various	ADJ
gs-3921	712	14	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	712	15	applications	application	NOUN
gs-3921	712	16	.	.	PUNCT
gs-3921	713	1	experimental	experimental	ADJ
gs-3921	713	2	and	and	CCONJ
gs-3921	713	3	clinical	clinical	ADJ
gs-3921	713	4	medicine	medicine	NOUN
gs-3921	713	5	georgia	georgia	PROPN
gs-3921	713	6	,	,	PUNCT
gs-3921	713	7	(	(	PUNCT
gs-3921	713	8	4	4	NUM
gs-3921	713	9	)	)	PUNCT
gs-3921	713	10	,	,	PUNCT
gs-3921	713	11	52–57	52–57	NUM
gs-3921	713	12	.	.	PUNCT
gs-3921	714	1	16	16	NUM
gs-3921	714	2	.	.	PUNCT
gs-3921	714	3	sulashvili	sulashvili	NOUN
gs-3921	714	4	,	,	PUNCT
gs-3921	714	5	n.	n.	NOUN
gs-3921	714	6	,	,	PUNCT
gs-3921	714	7	davitashvili	davitashvili	ADJ
gs-3921	714	8	,	,	PUNCT
gs-3921	714	9	m.	m.	NOUN
gs-3921	714	10	,	,	PUNCT
gs-3921	714	11	gorgaslidze	gorgaslidze	PROPN
gs-3921	714	12	,	,	PUNCT
gs-3921	714	13	n.	n.	NOUN
gs-3921	714	14	,	,	PUNCT
gs-3921	714	15	gabunia	gabunia	NOUN
gs-3921	714	16	,	,	PUNCT
gs-3921	714	17	l.	l.	PROPN
gs-3921	714	18	,	,	PUNCT
gs-3921	714	19	beglaryan	beglaryan	ADJ
gs-3921	714	20	,	,	PUNCT
gs-3921	714	21	m.	m.	NOUN
gs-3921	714	22	,	,	PUNCT
gs-3921	714	23	alavidze	alavidze	NOUN
gs-3921	714	24	,	,	PUNCT
gs-3921	714	25	n.	n.	NOUN
gs-3921	714	26	,	,	PUNCT
gs-3921	714	27	…	…	PUNCT
gs-3921	714	28	sulashvili	sulashvili	NOUN
gs-3921	714	29	,	,	PUNCT
gs-3921	714	30	m.	m.	NOUN
gs-3921	714	31	(	(	PUNCT
gs-3921	714	32	2024	2024	NUM
gs-3921	714	33	)	)	PUNCT
gs-3921	714	34	.	.	PUNCT
gs-3921	715	1	the	the	DET
gs-3921	715	2	scientific	scientific	ADJ
gs-3921	715	3	discussion	discussion	NOUN
gs-3921	715	4	of	of	ADP
gs-3921	715	5	some	some	DET
gs-3921	715	6	issues	issue	NOUN
gs-3921	715	7	of	of	ADP
gs-3921	715	8	features	feature	NOUN
gs-3921	715	9	and	and	CCONJ
gs-3921	715	10	challenges	challenge	NOUN
gs-3921	715	11	of	of	ADP
gs-3921	715	12	using	use	VERB
gs-3921	715	13	of	of	ADP
gs-3921	715	14	car	car	NOUN
gs-3921	715	15	-	-	PUNCT
gs-3921	715	16	t	t	NOUN
gs-3921	715	17	cells	cell	NOUN
gs-3921	715	18	in	in	ADP
gs-3921	715	19	immunotherapy	immunotherapy	NOUN
gs-3921	715	20	.	.	PUNCT
gs-3921	716	1	georgian	georgian	ADJ
gs-3921	716	2	scientists	scientist	NOUN
gs-3921	716	3	,	,	PUNCT
gs-3921	716	4	6(4	6(4	NOUN
gs-3921	716	5	)	)	PUNCT
gs-3921	716	6	,	,	PUNCT
gs-3921	716	7	263–290	263–290	NUM
gs-3921	716	8	.	.	PUNCT
gs-3921	716	9	https://doi.org/10.52340/gs.2024.06.04.24	https://doi.org/10.52340/gs.2024.06.04.24	PROPN
gs-3921	716	10	17	17	NUM
gs-3921	716	11	.	.	PUNCT
gs-3921	717	1	sulashvili	sulashvili	NOUN
gs-3921	717	2	,	,	PUNCT
gs-3921	717	3	n.	n.	NOUN
gs-3921	717	4	,	,	PUNCT
gs-3921	717	5	gorgaslidze	gorgaslidze	PROPN
gs-3921	717	6	,	,	PUNCT
gs-3921	717	7	n.	n.	NOUN
gs-3921	717	8	,	,	PUNCT
gs-3921	717	9	gabunia	gabunia	NOUN
gs-3921	717	10	,	,	PUNCT
gs-3921	717	11	l.	l.	PROPN
gs-3921	717	12	,	,	PUNCT
gs-3921	717	13	giorgobiani	giorgobiani	PROPN
gs-3921	717	14	,	,	PUNCT
gs-3921	717	15	m.	m.	NOUN
gs-3921	717	16	,	,	PUNCT
gs-3921	717	17	&	&	CCONJ
gs-3921	717	18	ratiani	ratiani	PROPN
gs-3921	717	19	,	,	PUNCT
gs-3921	717	20	l.	l.	PROPN
gs-3921	717	21	(	(	PUNCT
gs-3921	717	22	2023	2023	NUM
gs-3921	717	23	)	)	PUNCT
gs-3921	717	24	.	.	PUNCT
gs-3921	718	1	manifestation	manifestation	NOUN
gs-3921	718	2	of	of	ADP
gs-3921	718	3	the	the	DET
gs-3921	718	4	particularities	particularity	NOUN
gs-3921	718	5	of	of	ADP
gs-3921	718	6	the	the	DET
gs-3921	718	7	usage	usage	NOUN
gs-3921	718	8	features	feature	VERB
gs-3921	718	9	georgian	georgian	PROPN
gs-3921	718	10	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	718	11	მეცნიერები	მეცნიერები	NOUN
gs-3921	718	12	ტ.	ტ.	VERB
gs-3921	718	13	7	7	NUM
gs-3921	718	14	n	n	PRON
gs-3921	718	15	3	3	NUM
gs-3921	718	16	,	,	PUNCT
gs-3921	718	17	2025	2025	NUM
gs-3921	718	18	257	257	NUM
gs-3921	718	19	of	of	ADP
gs-3921	718	20	monoclonal	monoclonal	NOUN
gs-3921	718	21	antibodies	antibody	NOUN
gs-3921	718	22	in	in	ADP
gs-3921	718	23	various	various	ADJ
gs-3921	718	24	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	718	25	applications	application	NOUN
gs-3921	718	26	.	.	PUNCT
gs-3921	719	1	experimental	experimental	ADJ
gs-3921	719	2	and	and	CCONJ
gs-3921	719	3	clinical	clinical	ADJ
gs-3921	719	4	medicine	medicine	NOUN
gs-3921	719	5	georgia	georgia	PROPN
gs-3921	719	6	,	,	PUNCT
gs-3921	719	7	(	(	PUNCT
gs-3921	719	8	4	4	NUM
gs-3921	719	9	)	)	PUNCT
gs-3921	719	10	,	,	PUNCT
gs-3921	719	11	52–57	52–57	NUM
gs-3921	719	12	.	.	PUNCT
gs-3921	720	1	https://doi.org/10.52340/jecm.2023.04.14	https://doi.org/10.52340/jecm.2023.04.14	X
gs-3921	721	1	18	18	NUM
gs-3921	721	2	.	.	PUNCT
gs-3921	721	3	sulashvili	sulashvili	NOUN
gs-3921	721	4	,	,	PUNCT
gs-3921	721	5	n.	n.	NOUN
gs-3921	721	6	,	,	PUNCT
gs-3921	721	7	gorgaslidze	gorgaslidze	PROPN
gs-3921	721	8	,	,	PUNCT
gs-3921	721	9	n.	n.	NOUN
gs-3921	721	10	,	,	PUNCT
gs-3921	721	11	gabunia	gabunia	NOUN
gs-3921	721	12	,	,	PUNCT
gs-3921	721	13	l.	l.	PROPN
gs-3921	721	14	,	,	PUNCT
gs-3921	721	15	ratiani	ratiani	PROPN
gs-3921	721	16	,	,	PUNCT
gs-3921	721	17	l.	l.	PROPN
gs-3921	721	18	,	,	PUNCT
gs-3921	721	19	khetsuriani	khetsuriani	PROPN
gs-3921	721	20	,	,	PUNCT
gs-3921	721	21	s.	s.	PROPN
gs-3921	721	22	,	,	PUNCT
gs-3921	721	23	kravchenko	kravchenko	PROPN
gs-3921	721	24	,	,	PUNCT
gs-3921	721	25	v.	v.	NOUN
gs-3921	721	26	,	,	PUNCT
gs-3921	721	27	sulashvili	sulashvili	NOUN
gs-3921	721	28	,	,	PUNCT
gs-3921	721	29	m.	m.	NOUN
gs-3921	721	30	(	(	PUNCT
gs-3921	721	31	2024	2024	NUM
gs-3921	721	32	)	)	PUNCT
gs-3921	721	33	.	.	PUNCT
gs-3921	722	1	manifestation	manifestation	NOUN
gs-3921	722	2	of	of	ADP
gs-3921	722	3	the	the	DET
gs-3921	722	4	particularities	particularity	NOUN
gs-3921	722	5	of	of	ADP
gs-3921	722	6	some	some	DET
gs-3921	722	7	key	key	ADJ
gs-3921	722	8	issue	issue	NOUN
gs-3921	722	9	aspects	aspect	NOUN
gs-3921	722	10	of	of	ADP
gs-3921	722	11	new	new	ADJ
gs-3921	722	12	immunotherapy	immunotherapy	NOUN
gs-3921	722	13	challenges	challenge	NOUN
gs-3921	722	14	and	and	CCONJ
gs-3921	722	15	perspectives	perspective	NOUN
gs-3921	722	16	by	by	ADP
gs-3921	722	17	car	car	NOUN
gs-3921	722	18	-	-	PUNCT
gs-3921	722	19	t	t	NOUN
gs-3921	722	20	cell	cell	NOUN
gs-3921	722	21	therapy	therapy	NOUN
gs-3921	722	22	.	.	PUNCT
gs-3921	723	1	experimental	experimental	ADJ
gs-3921	723	2	and	and	CCONJ
gs-3921	723	3	clinical	clinical	ADJ
gs-3921	723	4	medicine	medicine	NOUN
gs-3921	723	5	georgia	georgia	PROPN
gs-3921	723	6	,	,	PUNCT
gs-3921	723	7	(	(	PUNCT
gs-3921	723	8	4	4	NUM
gs-3921	723	9	)	)	PUNCT
gs-3921	723	10	,	,	PUNCT
gs-3921	723	11	119–121	119–121	NUM
gs-3921	723	12	.	.	PUNCT
gs-3921	724	1	https://doi.org/10.52340/jecm.2024.04.32	https://doi.org/10.52340/jecm.2024.04.32	NUM
gs-3921	724	2	.	.	NOUN
gs-3921	725	1	19	19	NUM
gs-3921	725	2	.	.	PUNCT
gs-3921	725	3	sulashvili	sulashvili	NOUN
gs-3921	725	4	,	,	PUNCT
gs-3921	725	5	n.	n.	NOUN
gs-3921	725	6	.	.	PUNCT
gs-3921	726	1	.	.	PUNCT
gs-3921	726	2	,	,	PUNCT
gs-3921	727	1	gorgaslidze	gorgaslidze	INTJ
gs-3921	727	2	,	,	PUNCT
gs-3921	727	3	n.	n.	PROPN
gs-3921	727	4	.	.	PUNCT
gs-3921	728	1	,	,	PUNCT
gs-3921	728	2	beglaryan	beglaryan	ADJ
gs-3921	728	3	,	,	PUNCT
gs-3921	728	4	m.	m.	NOUN
gs-3921	728	5	.	.	PUNCT
gs-3921	728	6	,	,	PUNCT
gs-3921	728	7	gabunia	gabunia	NOUN
gs-3921	728	8	,	,	PUNCT
gs-3921	728	9	l.	l.	PROPN
gs-3921	728	10	.	.	PROPN
gs-3921	728	11	,	,	PUNCT
gs-3921	728	12	chichoyan	chichoyan	PROPN
gs-3921	728	13	,	,	PUNCT
gs-3921	728	14	n.	n.	PROPN
gs-3921	728	15	.	.	PUNCT
gs-3921	728	16	,	,	PUNCT
gs-3921	728	17	giorgobiani	giorgobiani	PROPN
gs-3921	728	18	,	,	PUNCT
gs-3921	728	19	m.	m.	NOUN
gs-3921	728	20	.	.	PUNCT
gs-3921	729	1	,	,	PUNCT
gs-3921	729	2	…	…	PUNCT
gs-3921	729	3	zarnadze	zarnadze	INTJ
gs-3921	729	4	,	,	PUNCT
gs-3921	729	5	s.	s.	PROPN
gs-3921	729	6	(	(	PUNCT
gs-3921	729	7	davit	davit	PROPN
gs-3921	729	8	)	)	PUNCT
gs-3921	729	9	.	.	PUNCT
gs-3921	730	1	(	(	PUNCT
gs-3921	730	2	2022	2022	NUM
gs-3921	730	3	)	)	PUNCT
gs-3921	730	4	.	.	PUNCT
gs-3921	731	1	the	the	DET
gs-3921	731	2	scientific	scientific	ADJ
gs-3921	731	3	talks	talk	NOUN
gs-3921	731	4	of	of	ADP
gs-3921	731	5	essential	essential	ADJ
gs-3921	731	6	issue	issue	NOUN
gs-3921	731	7	,	,	PUNCT
gs-3921	731	8	invocation	invocation	NOUN
gs-3921	731	9	,	,	PUNCT
gs-3921	731	10	perspectives	perspective	NOUN
gs-3921	731	11	,	,	PUNCT
gs-3921	731	12	inclinations	inclination	NOUN
gs-3921	731	13	and	and	CCONJ
gs-3921	731	14	features	feature	NOUN
gs-3921	731	15	of	of	ADP
gs-3921	731	16	the	the	DET
gs-3921	731	17	clinical	clinical	ADJ
gs-3921	731	18	pharmacists	pharmacist	NOUN
gs-3921	731	19	globally	globally	ADV
gs-3921	731	20	.	.	PUNCT
gs-3921	732	1	experimental	experimental	ADJ
gs-3921	732	2	and	and	CCONJ
gs-3921	732	3	clinical	clinical	ADJ
gs-3921	732	4	medicine	medicine	NOUN
gs-3921	732	5	georgia	georgia	PROPN
gs-3921	732	6	,	,	PUNCT
gs-3921	732	7	(	(	PUNCT
gs-3921	732	8	7	7	NUM
gs-3921	732	9	)	)	PUNCT
gs-3921	732	10	.	.	PUNCT
gs-3921	733	1	20	20	NUM
gs-3921	733	2	.	.	PUNCT
gs-3921	734	1	sulashvili	sulashvili	PROPN
gs-3921	734	2	n	n	CCONJ
gs-3921	734	3	,	,	PUNCT
gs-3921	734	4	nimangre	nimangre	PROPN
gs-3921	734	5	rr	rr	PROPN
gs-3921	734	6	.	.	PUNCT
gs-3921	735	1	manifestation	manifestation	NOUN
gs-3921	735	2	of	of	ADP
gs-3921	735	3	some	some	DET
gs-3921	735	4	aspects	aspect	NOUN
gs-3921	735	5	of	of	ADP
gs-3921	735	6	cardiovascular	cardiovascular	ADJ
gs-3921	735	7	diseases	disease	NOUN
gs-3921	735	8	,	,	PUNCT
gs-3921	735	9	implications	implication	NOUN
gs-3921	735	10	,	,	PUNCT
gs-3921	735	11	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	735	12	strategies	strategy	NOUN
gs-3921	735	13	,	,	PUNCT
gs-3921	735	14	effects	effect	NOUN
gs-3921	735	15	,	,	PUNCT
gs-3921	735	16	impacts	impact	NOUN
gs-3921	735	17	and	and	CCONJ
gs-3921	735	18	potential	potential	ADJ
gs-3921	735	19	hazards	hazard	NOUN
gs-3921	735	20	in	in	ADP
gs-3921	735	21	general	general	ADJ
gs-3921	735	22	.	.	PUNCT
gs-3921	736	1	jr	jr	PROPN
gs-3921	737	1	[	[	X
gs-3921	737	2	internet	internet	NOUN
gs-3921	737	3	]	]	PUNCT
gs-3921	737	4	.	.	PUNCT
gs-3921	738	1	2025	2025	NUM
gs-3921	738	2	feb	feb	X
gs-3921	738	3	.	.	PROPN
gs-3921	738	4	7	7	NUM
gs-3921	738	5	[	[	X
gs-3921	738	6	cited	cite	VERB
gs-3921	738	7	2025	2025	NUM
gs-3921	738	8	may	may	PROPN
gs-3921	738	9	22];3(1):1	22];3(1):1	NUM
gs-3921	738	10	-	-	SYM
gs-3921	738	11	27	27	NUM
gs-3921	738	12	.	.	PUNCT
gs-3921	739	1	available	available	ADJ
gs-3921	739	2	from	from	ADP
gs-3921	739	3	:	:	PUNCT
gs-3921	739	4	https://journals.4science.ge/index.php/jr/article/view/3393	https://journals.4science.ge/index.php/jr/article/view/3393	PROPN
gs-3921	739	5	.	.	PUNCT
gs-3921	740	1	21	21	NUM
gs-3921	740	2	.	.	PUNCT
gs-3921	741	1	sulashvili	sulashvili	PROPN
gs-3921	741	2	n	n	CCONJ
gs-3921	741	3	,	,	PUNCT
gs-3921	741	4	yaduvanshi	yaduvanshi	NOUN
gs-3921	741	5	u	u	NOUN
gs-3921	741	6	,	,	PUNCT
gs-3921	741	7	yadav	yadav	PROPN
gs-3921	741	8	m	m	PROPN
gs-3921	741	9	,	,	PUNCT
gs-3921	741	10	gabunia	gabunia	NOUN
gs-3921	741	11	l	l	NOUN
gs-3921	741	12	,	,	PUNCT
gs-3921	741	13	ghambashidze	ghambashidze	PROPN
gs-3921	741	14	k	k	PROPN
gs-3921	741	15	,	,	PUNCT
gs-3921	741	16	gorgaslidze	gorgaslidze	ADJ
gs-3921	741	17	n	n	CCONJ
gs-3921	741	18	,	,	PUNCT
gs-3921	741	19	et	et	PROPN
gs-3921	741	20	al	al	PROPN
gs-3921	741	21	.	.	PUNCT
gs-3921	742	1	the	the	DET
gs-3921	742	2	scientific	scientific	ADJ
gs-3921	742	3	discourse	discourse	NOUN
gs-3921	742	4	of	of	ADP
gs-3921	742	5	features	feature	NOUN
gs-3921	742	6	of	of	ADP
gs-3921	742	7	clinical	clinical	ADJ
gs-3921	742	8	use	use	NOUN
gs-3921	742	9	and	and	CCONJ
gs-3921	742	10	pharmacology	pharmacology	NOUN
gs-3921	742	11	of	of	ADP
gs-3921	742	12	vasoconstrictors	vasoconstrictor	NOUN
gs-3921	742	13	and	and	CCONJ
gs-3921	742	14	their	their	PRON
gs-3921	742	15	impact	impact	NOUN
gs-3921	742	16	on	on	ADP
gs-3921	742	17	cardiac	cardiac	ADJ
gs-3921	742	18	function	function	NOUN
gs-3921	742	19	.	.	PUNCT
gs-3921	743	1	jr	jr	PROPN
gs-3921	744	1	[	[	X
gs-3921	744	2	internet	internet	NOUN
gs-3921	744	3	]	]	PUNCT
gs-3921	744	4	.	.	PUNCT
gs-3921	745	1	2025	2025	NUM
gs-3921	745	2	feb	feb	X
gs-3921	745	3	.	.	PROPN
gs-3921	745	4	21	21	NUM
gs-3921	745	5	[	[	X
gs-3921	745	6	cited	cite	VERB
gs-3921	745	7	2025	2025	NUM
gs-3921	745	8	may	may	PROPN
gs-3921	745	9	22];3(1):28	22];3(1):28	NUM
gs-3921	745	10	-	-	SYM
gs-3921	745	11	6	6	NUM
gs-3921	745	12	.	.	PUNCT
gs-3921	746	1	available	available	ADJ
gs-3921	746	2	from	from	ADP
gs-3921	746	3	:	:	PUNCT
gs-3921	746	4	https://journals.4science.ge/index.php/jr/article/view/3414	https://journals.4science.ge/index.php/jr/article/view/3414	NOUN
gs-3921	746	5	.	.	PUNCT
gs-3921	747	1	22	22	NUM
gs-3921	747	2	.	.	PUNCT
gs-3921	748	1	nodar	nodar	PROPN
gs-3921	748	2	sulashvili	sulashvili	NOUN
gs-3921	748	3	,	,	PUNCT
gs-3921	748	4	nana	nana	PROPN
gs-3921	748	5	gorgaslidze	gorgaslidze	PROPN
gs-3921	748	6	,	,	PUNCT
gs-3921	748	7	margarita	margarita	PROPN
gs-3921	748	8	beglaryan	beglaryan	PROPN
gs-3921	748	9	,	,	PUNCT
gs-3921	748	10	luiza	luiza	PROPN
gs-3921	748	11	gabunia	gabunia	PROPN
gs-3921	748	12	,	,	PUNCT
gs-3921	748	13	nato	nato	PROPN
gs-3921	748	14	alavidze	alavidze	PROPN
gs-3921	748	15	,	,	PUNCT
gs-3921	748	16	nino	nino	PROPN
gs-3921	748	17	abuladze	abuladze	PROPN
gs-3921	748	18	,	,	PUNCT
gs-3921	748	19	marina	marina	PROPN
gs-3921	748	20	giorgobiani	giorgobiani	PROPN
gs-3921	748	21	,	,	PUNCT
gs-3921	748	22	marika	marika	PROPN
gs-3921	748	23	sulashvili	sulashvili	PROPN
gs-3921	748	24	,	,	PUNCT
gs-3921	748	25	tamar	tamar	PROPN
gs-3921	748	26	okropiridze	okropiridze	PROPN
gs-3921	748	27	,	,	PUNCT
gs-3921	748	28	and	and	CCONJ
gs-3921	748	29	lali	lali	PROPN
gs-3921	748	30	patsia	patsia	PROPN
gs-3921	748	31	.	.	PUNCT
gs-3921	749	1	2025	2025	NUM
gs-3921	749	2	.	.	PUNCT
gs-3921	750	1	“	"	PUNCT
gs-3921	750	2	the	the	DET
gs-3921	750	3	scientific	scientific	ADJ
gs-3921	750	4	discourse	discourse	NOUN
gs-3921	750	5	of	of	ADP
gs-3921	750	6	key	key	ADJ
gs-3921	750	7	issue	issue	NOUN
gs-3921	750	8	aspects	aspect	NOUN
gs-3921	750	9	of	of	ADP
gs-3921	750	10	features	feature	NOUN
gs-3921	750	11	of	of	ADP
gs-3921	750	12	candida	candida	PROPN
gs-3921	750	13	problems	problem	NOUN
gs-3921	750	14	,	,	PUNCT
gs-3921	750	15	antifungal	antifungal	ADJ
gs-3921	750	16	drugs	drug	NOUN
gs-3921	750	17	resistance	resistance	NOUN
gs-3921	750	18	concerns	concern	NOUN
gs-3921	750	19	,	,	PUNCT
gs-3921	750	20	mycotoxicology	mycotoxicology	NOUN
gs-3921	750	21	issues	issue	NOUN
gs-3921	750	22	,	,	PUNCT
gs-3921	750	23	mycoecology	mycoecology	NOUN
gs-3921	750	24	,	,	PUNCT
gs-3921	750	25	biosafety	biosafety	NOUN
gs-3921	750	26	risks	risk	NOUN
gs-3921	750	27	and	and	CCONJ
gs-3921	750	28	emerging	emerge	VERB
gs-3921	750	29	solutions	solution	NOUN
gs-3921	750	30	”	"	PUNCT
gs-3921	750	31	.	.	PUNCT
gs-3921	751	1	modern	modern	ADJ
gs-3921	751	2	scientific	scientific	ADJ
gs-3921	751	3	method	method	NOUN
gs-3921	751	4	,	,	PUNCT
gs-3921	751	5	no	no	INTJ
gs-3921	751	6	.	.	NOUN
gs-3921	751	7	9	9	NUM
gs-3921	751	8	(	(	PUNCT
gs-3921	751	9	march	march	PROPN
gs-3921	751	10	)	)	PUNCT
gs-3921	751	11	.	.	PUNCT
gs-3921	752	1	https://ojs.scipub.de/index.php/msm/article/view/5423	https://ojs.scipub.de/index.php/msm/article/view/5423	NOUN
gs-3921	752	2	.	.	NOUN
gs-3921	752	3	23	23	NUM
gs-3921	752	4	.	.	X
gs-3921	753	1	aphkhazava	aphkhazava	PROPN
gs-3921	753	2	,	,	PUNCT
gs-3921	753	3	d.	d.	PROPN
gs-3921	753	4	,	,	PUNCT
gs-3921	753	5	tuphinashvili	tuphinashvili	NOUN
gs-3921	753	6	,	,	PUNCT
gs-3921	753	7	t.	t.	NOUN
gs-3921	753	8	,	,	PUNCT
gs-3921	753	9	sulashvili	sulashvili	NOUN
gs-3921	753	10	,	,	PUNCT
gs-3921	753	11	n.	n.	NOUN
gs-3921	753	12	,	,	PUNCT
gs-3921	753	13	&	&	CCONJ
gs-3921	753	14	nozadze	nozadze	NOUN
gs-3921	753	15	,	,	PUNCT
gs-3921	753	16	m.	m.	NOUN
gs-3921	753	17	(	(	PUNCT
gs-3921	753	18	2023	2023	NUM
gs-3921	753	19	)	)	PUNCT
gs-3921	753	20	.	.	PUNCT
gs-3921	754	1	the	the	DET
gs-3921	754	2	features	feature	NOUN
gs-3921	754	3	and	and	CCONJ
gs-3921	754	4	role	role	NOUN
gs-3921	754	5	of	of	ADP
gs-3921	754	6	shp2	shp2	ADJ
gs-3921	754	7	protein	protein	NOUN
gs-3921	754	8	in	in	ADP
gs-3921	754	9	postnatal	postnatal	ADJ
gs-3921	754	10	muscle	muscle	NOUN
gs-3921	754	11	development	development	NOUN
gs-3921	754	12	.	.	PUNCT
gs-3921	755	1	scientific	scientific	ADJ
gs-3921	755	2	journal	journal	NOUN
gs-3921	755	3	„	„	PUNCT
gs-3921	755	4	spectri	spectri	NOUN
gs-3921	755	5	“	"	PUNCT
gs-3921	755	6	,	,	PUNCT
gs-3921	755	7	1	1	X
gs-3921	755	8	.	.	PUNCT
gs-3921	756	1	https://doi.org/10.52340/spectri.2023.01	https://doi.org/10.52340/spectri.2023.01	DET
gs-3921	756	2	24	24	NUM
gs-3921	756	3	.	.	PUNCT
gs-3921	756	4	sulashvili	sulashvili	NOUN
gs-3921	756	5	,	,	PUNCT
gs-3921	756	6	n.	n.	NOUN
gs-3921	756	7	,	,	PUNCT
gs-3921	756	8	beglaryan	beglaryan	ADJ
gs-3921	756	9	,	,	PUNCT
gs-3921	756	10	m.	m.	NOUN
gs-3921	756	11	,	,	PUNCT
gs-3921	756	12	gorgaslidze	gorgaslidze	PROPN
gs-3921	756	13	,	,	PUNCT
gs-3921	756	14	n.	n.	PROPN
gs-3921	756	15	,	,	PUNCT
gs-3921	756	16	kocharyan	kocharyan	PROPN
gs-3921	756	17	,	,	PUNCT
gs-3921	756	18	s.	s.	PROPN
gs-3921	756	19	,	,	PUNCT
gs-3921	756	20	chichoyan	chichoyan	PROPN
gs-3921	756	21	,	,	PUNCT
gs-3921	756	22	n.	n.	NOUN
gs-3921	756	23	,	,	PUNCT
gs-3921	756	24	gabunia	gabunia	NOUN
gs-3921	756	25	,	,	PUNCT
gs-3921	756	26	l.	l.	PROPN
gs-3921	756	27	,	,	PUNCT
gs-3921	756	28	zarnadze	zarnadze	PROPN
gs-3921	756	29	,	,	PUNCT
gs-3921	756	30	s.	s.	PROPN
gs-3921	756	31	(	(	PUNCT
gs-3921	756	32	davit	davit	PROPN
gs-3921	756	33	)	)	PUNCT
gs-3921	756	34	.	.	PUNCT
gs-3921	757	1	(	(	PUNCT
gs-3921	757	2	2023	2023	NUM
gs-3921	757	3	)	)	PUNCT
gs-3921	757	4	.	.	PUNCT
gs-3921	758	1	the	the	DET
gs-3921	758	2	disclosure	disclosure	NOUN
gs-3921	758	3	of	of	ADP
gs-3921	758	4	features	feature	NOUN
gs-3921	758	5	,	,	PUNCT
gs-3921	758	6	characteristics	characteristic	NOUN
gs-3921	758	7	,	,	PUNCT
gs-3921	758	8	possibilities	possibility	NOUN
gs-3921	758	9	and	and	CCONJ
gs-3921	758	10	specialties	specialty	NOUN
gs-3921	758	11	of	of	ADP
gs-3921	758	12	clinical	clinical	ADJ
gs-3921	758	13	pharmacists	pharmacist	NOUN
gs-3921	758	14	as	as	ADP
gs-3921	758	15	mediator	mediator	NOUN
gs-3921	758	16	among	among	ADP
gs-3921	758	17	doctors	doctor	NOUN
gs-3921	758	18	and	and	CCONJ
gs-3921	758	19	patients	patient	NOUN
gs-3921	758	20	for	for	ADP
gs-3921	758	21	enhancement	enhancement	NOUN
gs-3921	758	22	public	public	ADJ
gs-3921	758	23	health	health	NOUN
gs-3921	758	24	sector	sector	NOUN
gs-3921	758	25	in	in	ADP
gs-3921	758	26	a	a	DET
gs-3921	758	27	global	global	ADJ
gs-3921	758	28	world	world	NOUN
gs-3921	758	29	.	.	PUNCT
gs-3921	759	1	experimental	experimental	ADJ
gs-3921	759	2	and	and	CCONJ
gs-3921	759	3	clinical	clinical	ADJ
gs-3921	759	4	medicine	medicine	NOUN
gs-3921	759	5	georgia	georgia	PROPN
gs-3921	759	6	,	,	PUNCT
gs-3921	759	7	(	(	PUNCT
gs-3921	759	8	4	4	NUM
gs-3921	759	9	)	)	PUNCT
gs-3921	759	10	,	,	PUNCT
gs-3921	759	11	57–62	57–62	NUM
gs-3921	759	12	.	.	PUNCT
gs-3921	760	1	https://doi.org/10.52340/jecm.2023.04.15	https://doi.org/10.52340/jecm.2023.04.15	X
gs-3921	760	2	georgian	georgian	ADJ
gs-3921	760	3	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	760	4	მეცნიერები	მეცნიერები	NOUN
gs-3921	760	5	ტ.	ტ.	VERB
gs-3921	760	6	7	7	NUM
gs-3921	760	7	n	n	PRON
gs-3921	760	8	3	3	NUM
gs-3921	760	9	,	,	PUNCT
gs-3921	760	10	2025	2025	NUM
gs-3921	760	11	258	258	NUM
gs-3921	760	12	25	25	NUM
gs-3921	760	13	.	.	PUNCT
gs-3921	761	1	sulashvili	sulashvili	PROPN
gs-3921	761	2	n	n	CCONJ
gs-3921	761	3	,	,	PUNCT
gs-3921	761	4	davitashvili	davitashvili	PROPN
gs-3921	761	5	m	m	PROPN
gs-3921	761	6	,	,	PUNCT
gs-3921	761	7	gorgaslidze	gorgaslidze	ADJ
gs-3921	761	8	n	n	CCONJ
gs-3921	761	9	,	,	PUNCT
gs-3921	761	10	gabunia	gabunia	NOUN
gs-3921	761	11	l	l	NOUN
gs-3921	761	12	,	,	PUNCT
gs-3921	761	13	beglaryan	beglaryan	PROPN
gs-3921	761	14	m	m	PROPN
gs-3921	761	15	,	,	PUNCT
gs-3921	761	16	alavidze	alavidze	PROPN
gs-3921	761	17	n	n	CCONJ
gs-3921	761	18	,	,	PUNCT
gs-3921	761	19	et	et	PROPN
gs-3921	761	20	al	al	PROPN
gs-3921	761	21	.	.	PUNCT
gs-3921	762	1	the	the	DET
gs-3921	762	2	scientific	scientific	ADJ
gs-3921	762	3	discussion	discussion	NOUN
gs-3921	762	4	of	of	ADP
gs-3921	762	5	some	some	DET
gs-3921	762	6	issues	issue	NOUN
gs-3921	762	7	of	of	ADP
gs-3921	762	8	features	feature	NOUN
gs-3921	762	9	and	and	CCONJ
gs-3921	762	10	challenges	challenge	NOUN
gs-3921	762	11	of	of	ADP
gs-3921	762	12	using	use	VERB
gs-3921	762	13	of	of	ADP
gs-3921	762	14	car	car	NOUN
gs-3921	762	15	-	-	PUNCT
gs-3921	762	16	t	t	NOUN
gs-3921	762	17	cells	cell	NOUN
gs-3921	762	18	in	in	ADP
gs-3921	762	19	immunotherapy	immunotherapy	NOUN
gs-3921	762	20	.	.	PUNCT
gs-3921	763	1	gs	gs	X
gs-3921	764	1	[	[	X
gs-3921	764	2	internet	internet	NOUN
gs-3921	764	3	]	]	PUNCT
gs-3921	764	4	.	.	PUNCT
gs-3921	765	1	2024	2024	NUM
gs-3921	765	2	nov	nov	PROPN
gs-3921	765	3	.	.	PROPN
gs-3921	765	4	26	26	NUM
gs-3921	765	5	[	[	X
gs-3921	765	6	cited	cite	VERB
gs-3921	765	7	2025	2025	NUM
gs-3921	765	8	jul	jul	PROPN
gs-3921	765	9	.	.	PUNCT
gs-3921	765	10	12];6(4):263	12];6(4):263	NUM
gs-3921	765	11	-	-	SYM
gs-3921	765	12	90	90	NUM
gs-3921	765	13	.	.	PUNCT
gs-3921	766	1	available	available	ADJ
gs-3921	766	2	from	from	ADP
gs-3921	766	3	:	:	PUNCT
gs-3921	766	4	https://journals.4science.ge/index.php/gs/article/view/3214	https://journals.4science.ge/index.php/gs/article/view/3214	PROPN
gs-3921	766	5	26	26	NUM
gs-3921	766	6	.	.	X
gs-3921	767	1	aphkhazava	aphkhazava	PROPN
gs-3921	767	2	,	,	PUNCT
gs-3921	767	3	david	david	PROPN
gs-3921	767	4	,	,	PUNCT
gs-3921	767	5	nodar	nodar	NOUN
gs-3921	767	6	sulashvili	sulashvili	NOUN
gs-3921	767	7	,	,	PUNCT
gs-3921	767	8	and	and	CCONJ
gs-3921	767	9	jaba	jaba	PROPN
gs-3921	767	10	tkemaladze	tkemaladze	PROPN
gs-3921	767	11	.	.	PUNCT
gs-3921	768	1	2025	2025	NUM
gs-3921	768	2	.	.	PUNCT
gs-3921	769	1	“	"	PUNCT
gs-3921	769	2	stem	stem	NOUN
gs-3921	769	3	cell	cell	NOUN
gs-3921	769	4	systems	system	NOUN
gs-3921	769	5	and	and	CCONJ
gs-3921	769	6	regeneration	regeneration	NOUN
gs-3921	769	7	”	"	PUNCT
gs-3921	769	8	.	.	PUNCT
gs-3921	770	1	georgian	georgian	PROPN
gs-3921	770	2	scientists	scientist	NOUN
gs-3921	770	3	7	7	NUM
gs-3921	770	4	(	(	PUNCT
gs-3921	770	5	1):271	1):271	NUM
gs-3921	770	6	-	-	SYM
gs-3921	770	7	319	319	NUM
gs-3921	770	8	.	.	PUNCT
gs-3921	771	1	https://doi.org/10.52340/gs.2025.07.01.26	https://doi.org/10.52340/gs.2025.07.01.26	NOUN
gs-3921	771	2	.	.	NOUN
gs-3921	771	3	27	27	NUM
gs-3921	771	4	.	.	X
gs-3921	772	1	relling	relle	VERB
gs-3921	772	2	,	,	PUNCT
gs-3921	772	3	mary	mary	PROPN
gs-3921	772	4	v.	v.	PROPN
gs-3921	772	5	,	,	PUNCT
gs-3921	772	6	and	and	CCONJ
gs-3921	772	7	william	william	PROPN
gs-3921	772	8	e.	e.	PROPN
gs-3921	772	9	evans	evans	PROPN
gs-3921	772	10	.	.	PROPN
gs-3921	772	11	2015	2015	NUM
gs-3921	772	12	.	.	PUNCT
gs-3921	773	1	“	"	PUNCT
gs-3921	773	2	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	773	3	in	in	ADP
gs-3921	773	4	the	the	DET
gs-3921	773	5	clinic	clinic	NOUN
gs-3921	773	6	.	.	PUNCT
gs-3921	773	7	”	"	PUNCT
gs-3921	774	1	nature	nature	NOUN
gs-3921	774	2	526	526	NUM
gs-3921	774	3	(	(	PUNCT
gs-3921	774	4	7573	7573	NUM
gs-3921	774	5	):	):	PUNCT
gs-3921	774	6	343–50	343–50	NUM
gs-3921	774	7	.	.	PUNCT
gs-3921	775	1	28	28	NUM
gs-3921	775	2	.	.	X
gs-3921	776	1	aphkhazava	aphkhazava	PROPN
gs-3921	776	2	,	,	PUNCT
gs-3921	776	3	david	david	PROPN
gs-3921	776	4	,	,	PUNCT
gs-3921	776	5	tamar	tamar	PROPN
gs-3921	776	6	tuphinashvili	tuphinashvili	PROPN
gs-3921	776	7	,	,	PUNCT
gs-3921	776	8	nodar	nodar	NOUN
gs-3921	776	9	sulashvili	sulashvili	NOUN
gs-3921	776	10	,	,	PUNCT
gs-3921	776	11	and	and	CCONJ
gs-3921	776	12	maia	maia	NOUN
gs-3921	776	13	nozadze	nozadze	NOUN
gs-3921	776	14	.	.	PUNCT
gs-3921	777	1	2023	2023	NUM
gs-3921	777	2	.	.	PUNCT
gs-3921	778	1	“	"	PUNCT
gs-3921	778	2	the	the	DET
gs-3921	778	3	features	feature	NOUN
gs-3921	778	4	and	and	CCONJ
gs-3921	778	5	role	role	NOUN
gs-3921	778	6	of	of	ADP
gs-3921	778	7	shp2	shp2	ADJ
gs-3921	778	8	protein	protein	NOUN
gs-3921	778	9	in	in	ADP
gs-3921	778	10	postnatal	postnatal	ADJ
gs-3921	778	11	muscle	muscle	NOUN
gs-3921	778	12	development	development	NOUN
gs-3921	778	13	”	"	PUNCT
gs-3921	778	14	.	.	PUNCT
gs-3921	779	1	scientific	scientific	ADJ
gs-3921	779	2	journal	journal	NOUN
gs-3921	779	3	„	„	PUNCT
gs-3921	779	4	spectri	spectri	ADJ
gs-3921	779	5	“	"	PUNCT
gs-3921	779	6	1	1	NUM
gs-3921	779	7	(	(	PUNCT
gs-3921	779	8	march	march	PROPN
gs-3921	779	9	)	)	PUNCT
gs-3921	779	10	.	.	PUNCT
gs-3921	780	1	https://doi.org/10.52340/spectri.2023.01	https://doi.org/10.52340/spectri.2023.01	PROPN
gs-3921	780	2	.	.	PUNCT
gs-3921	781	1	29	29	NUM
gs-3921	781	2	.	.	PUNCT
gs-3921	782	1	sulashvili	sulashvili	PROPN
gs-3921	782	2	n	n	CCONJ
gs-3921	782	3	,	,	PUNCT
gs-3921	782	4	gorgaslidze	gorgaslidze	ADJ
gs-3921	782	5	n	n	CCONJ
gs-3921	782	6	,	,	PUNCT
gs-3921	782	7	gabunia	gabunia	NOUN
gs-3921	782	8	l	l	NOUN
gs-3921	782	9	,	,	PUNCT
gs-3921	782	10	giorgobiani	giorgobiani	PROPN
gs-3921	782	11	m	m	PROPN
gs-3921	782	12	,	,	PUNCT
gs-3921	782	13	ratiani	ratiani	PROPN
gs-3921	782	14	l.	l.	PROPN
gs-3921	782	15	manifestation	manifestation	PROPN
gs-3921	782	16	of	of	ADP
gs-3921	782	17	the	the	DET
gs-3921	782	18	particularities	particularity	NOUN
gs-3921	782	19	of	of	ADP
gs-3921	782	20	the	the	DET
gs-3921	782	21	usage	usage	NOUN
gs-3921	782	22	features	feature	NOUN
gs-3921	782	23	of	of	ADP
gs-3921	782	24	monoclonal	monoclonal	NOUN
gs-3921	782	25	antibodies	antibody	NOUN
gs-3921	782	26	in	in	ADP
gs-3921	782	27	various	various	ADJ
gs-3921	782	28	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	782	29	applications	application	NOUN
gs-3921	782	30	.	.	PUNCT
gs-3921	783	1	jecmg	jecmg	NOUN
gs-3921	784	1	[	[	X
gs-3921	784	2	internet	internet	NOUN
gs-3921	784	3	]	]	X
gs-3921	784	4	.	.	PUNCT
gs-3921	785	1	2023	2023	NUM
gs-3921	785	2	nov	nov	PROPN
gs-3921	785	3	.	.	PROPN
gs-3921	785	4	26	26	NUM
gs-3921	785	5	[	[	X
gs-3921	785	6	cited	cite	VERB
gs-3921	785	7	2025	2025	NUM
gs-3921	785	8	jul	jul	PROPN
gs-3921	785	9	.	.	PROPN
gs-3921	785	10	12];(4):52	12];(4):52	NUM
gs-3921	785	11	-	-	SYM
gs-3921	785	12	7	7	NUM
gs-3921	785	13	.	.	PUNCT
gs-3921	785	14	available	available	ADJ
gs-3921	785	15	from	from	ADP
gs-3921	785	16	:	:	PUNCT
gs-3921	785	17	https://journals.4science.ge/index.php/jecm/article/view/2413	https://journals.4science.ge/index.php/jecm/article/view/2413	PROPN
gs-3921	785	18	.	.	PROPN
gs-3921	785	19	30	30	NUM
gs-3921	785	20	.	.	PUNCT
gs-3921	786	1	aphkhazava	aphkhazava	PROPN
gs-3921	786	2	,	,	PUNCT
gs-3921	786	3	david	david	PROPN
gs-3921	786	4	,	,	PUNCT
gs-3921	786	5	nodar	nodar	PROPN
gs-3921	786	6	sulashvili	sulashvili	NOUN
gs-3921	786	7	,	,	PUNCT
gs-3921	786	8	ia	ia	PROPN
gs-3921	786	9	egnatievi	egnatievi	PROPN
gs-3921	786	10	,	,	PUNCT
gs-3921	786	11	manana	manana	PROPN
gs-3921	786	12	giorgobiani	giorgobiani	PROPN
gs-3921	786	13	,	,	PUNCT
gs-3921	786	14	maia	maia	PROPN
gs-3921	786	15	nozadze	nozadze	PROPN
gs-3921	786	16	,	,	PUNCT
gs-3921	786	17	nani	nani	PROPN
gs-3921	786	18	vekua	vekua	NOUN
gs-3921	786	19	,	,	PUNCT
gs-3921	786	20	and	and	CCONJ
gs-3921	786	21	nino	nino	PROPN
gs-3921	786	22	japaridze	japaridze	PROPN
gs-3921	786	23	.	.	PUNCT
gs-3921	787	1	2024	2024	NUM
gs-3921	787	2	.	.	PUNCT
gs-3921	788	1	“	"	PUNCT
gs-3921	788	2	derivation	derivation	NOUN
gs-3921	788	3	of	of	ADP
gs-3921	788	4	ampa	ampa	NOUN
gs-3921	788	5	receptor	receptor	NOUN
gs-3921	788	6	glua1	glua1	NOUN
gs-3921	788	7	subunits	subunit	NOUN
gs-3921	788	8	in	in	ADP
gs-3921	788	9	mice	mouse	NOUN
gs-3921	788	10	from	from	ADP
gs-3921	788	11	exosomes	exosome	NOUN
gs-3921	788	12	modulates	modulate	NOUN
gs-3921	788	13	inflammatory	inflammatory	ADJ
gs-3921	788	14	pain	pain	NOUN
gs-3921	788	15	”	"	PUNCT
gs-3921	788	16	.	.	PUNCT
gs-3921	789	1	scientific	scientific	ADJ
gs-3921	789	2	journal	journal	NOUN
gs-3921	789	3	„	„	PUNCT
gs-3921	789	4	spectri	spectri	ADJ
gs-3921	789	5	“	"	PUNCT
gs-3921	789	6	9	9	NUM
gs-3921	789	7	(	(	PUNCT
gs-3921	789	8	1	1	NUM
gs-3921	789	9	)	)	PUNCT
gs-3921	789	10	.	.	PUNCT
gs-3921	790	1	https://doi.org/10.52340/spectri.2024.09.01.05	https://doi.org/10.52340/spectri.2024.09.01.05	NOUN
gs-3921	790	2	.	.	PROPN
gs-3921	791	1	31	31	NUM
gs-3921	791	2	.	.	X
gs-3921	792	1	aphkhazava	aphkhazava	PROPN
gs-3921	792	2	,	,	PUNCT
gs-3921	792	3	david	david	PROPN
gs-3921	792	4	,	,	PUNCT
gs-3921	792	5	nodar	nodar	PROPN
gs-3921	792	6	sulashvili	sulashvili	NOUN
gs-3921	792	7	,	,	PUNCT
gs-3921	792	8	ia	ia	PROPN
gs-3921	792	9	egnatievi	egnatievi	PROPN
gs-3921	792	10	,	,	PUNCT
gs-3921	792	11	tamar	tamar	PROPN
gs-3921	792	12	tupinashvili	tupinashvili	NOUN
gs-3921	792	13	,	,	PUNCT
gs-3921	792	14	and	and	CCONJ
gs-3921	792	15	maia	maia	PROPN
gs-3921	792	16	nozadze	nozadze	PROPN
gs-3921	792	17	.	.	PUNCT
gs-3921	793	1	2024	2024	NUM
gs-3921	793	2	.	.	PUNCT
gs-3921	794	1	“	"	PUNCT
gs-3921	794	2	dynamic	dynamic	ADJ
gs-3921	794	3	tumor	tumor	NOUN
gs-3921	794	4	microenvironment	microenvironment	NOUN
gs-3921	794	5	theory	theory	NOUN
gs-3921	794	6	:	:	PUNCT
gs-3921	794	7	a	a	DET
gs-3921	794	8	multifaceted	multifaceted	ADJ
gs-3921	794	9	approach	approach	NOUN
gs-3921	794	10	to	to	ADP
gs-3921	794	11	tumor	tumor	NOUN
gs-3921	794	12	research	research	NOUN
gs-3921	794	13	and	and	CCONJ
gs-3921	794	14	biochemistry	biochemistry	NOUN
gs-3921	794	15	”	"	PUNCT
gs-3921	794	16	.	.	PUNCT
gs-3921	795	1	scientific	scientific	ADJ
gs-3921	795	2	journal	journal	NOUN
gs-3921	795	3	„	„	PUNCT
gs-3921	795	4	spectri	spectri	ADJ
gs-3921	795	5	“	"	PUNCT
gs-3921	795	6	9	9	NUM
gs-3921	795	7	(	(	PUNCT
gs-3921	795	8	1	1	NUM
gs-3921	795	9	)	)	PUNCT
gs-3921	795	10	.	.	PUNCT
gs-3921	796	1	https://doi.org/10.52340/spectri.2024.09.01.06	https://doi.org/10.52340/spectri.2024.09.01.06	NOUN
gs-3921	796	2	.	.	PROPN
gs-3921	796	3	32	32	NUM
gs-3921	796	4	.	.	PUNCT
gs-3921	796	5	sulashvili	sulashvili	NOUN
gs-3921	796	6	,	,	PUNCT
gs-3921	796	7	nodar	nodar	ADV
gs-3921	796	8	,	,	PUNCT
gs-3921	796	9	irine	irine	NOUN
gs-3921	796	10	pkhakadze	pkhakadze	NOUN
gs-3921	796	11	,	,	PUNCT
gs-3921	796	12	margarita	margarita	PROPN
gs-3921	796	13	beglaryan	beglaryan	NOUN
gs-3921	796	14	,	,	PUNCT
gs-3921	796	15	ia	ia	PROPN
gs-3921	796	16	egnatievi	egnatievi	PROPN
gs-3921	796	17	,	,	PUNCT
gs-3921	796	18	manana	manana	PROPN
gs-3921	796	19	giorgobiani	giorgobiani	PROPN
gs-3921	796	20	,	,	PUNCT
gs-3921	796	21	luiza	luiza	PROPN
gs-3921	796	22	gabunia	gabunia	PROPN
gs-3921	796	23	,	,	PUNCT
gs-3921	796	24	nana	nana	PROPN
gs-3921	796	25	gorgaslidze	gorgaslidze	PROPN
gs-3921	796	26	,	,	PUNCT
gs-3921	796	27	magda	magda	PROPN
gs-3921	796	28	davitashvili	davitashvili	PROPN
gs-3921	796	29	,	,	PUNCT
gs-3921	796	30	ada	ada	PROPN
gs-3921	796	31	(	(	PUNCT
gs-3921	796	32	adel	adel	PROPN
gs-3921	796	33	)	)	PUNCT
gs-3921	796	34	tadevosyan	tadevosyan	PROPN
gs-3921	796	35	,	,	PUNCT
gs-3921	796	36	and	and	CCONJ
gs-3921	796	37	lali	lali	PROPN
gs-3921	796	38	patsia	patsia	PROPN
gs-3921	796	39	.	.	PUNCT
gs-3921	797	1	2025	2025	NUM
gs-3921	797	2	.	.	PUNCT
gs-3921	798	1	“	"	PUNCT
gs-3921	798	2	the	the	DET
gs-3921	798	3	scientific	scientific	ADJ
gs-3921	798	4	discussion	discussion	NOUN
gs-3921	798	5	of	of	ADP
gs-3921	798	6	key	key	ADJ
gs-3921	798	7	issue	issue	NOUN
gs-3921	798	8	aspects	aspect	NOUN
gs-3921	798	9	of	of	ADP
gs-3921	798	10	modern	modern	ADJ
gs-3921	798	11	advancing	advance	VERB
gs-3921	798	12	innovation	innovation	NOUN
gs-3921	798	13	of	of	ADP
gs-3921	798	14	learning	learning	NOUN
gs-3921	798	15	and	and	CCONJ
gs-3921	798	16	teaching	teaching	NOUN
gs-3921	798	17	methods	method	NOUN
gs-3921	798	18	and	and	CCONJ
gs-3921	798	19	pedagogical	pedagogical	ADJ
gs-3921	798	20	approaches	approach	NOUN
gs-3921	798	21	in	in	ADP
gs-3921	798	22	higher	high	ADJ
gs-3921	798	23	education	education	NOUN
gs-3921	798	24	institutions	institution	NOUN
gs-3921	798	25	in	in	ADP
gs-3921	798	26	medical	medical	ADJ
gs-3921	798	27	educational	educational	ADJ
gs-3921	798	28	study	study	NOUN
gs-3921	798	29	programs	program	NOUN
gs-3921	798	30	directions	direction	VERB
gs-3921	798	31	globally	globally	ADV
gs-3921	798	32	in	in	ADP
gs-3921	798	33	general	general	ADJ
gs-3921	798	34	”	"	PUNCT
gs-3921	798	35	.	.	PUNCT
gs-3921	799	1	scientific	scientific	ADJ
gs-3921	799	2	journal	journal	NOUN
gs-3921	799	3	„	„	PUNCT
gs-3921	799	4	spectri	spectri	ADJ
gs-3921	799	5	“	"	PUNCT
gs-3921	799	6	10	10	NUM
gs-3921	799	7	(	(	PUNCT
gs-3921	799	8	2	2	NUM
gs-3921	799	9	)	)	PUNCT
gs-3921	799	10	.	.	PUNCT
gs-3921	800	1	https://doi.org/10.52340/spectri.2024.10.01.12	https://doi.org/10.52340/spectri.2024.10.01.12	PUNCT
gs-3921	800	2	.	.	X
gs-3921	801	1	33	33	NUM
gs-3921	801	2	.	.	PUNCT
gs-3921	802	1	gorgaslidze	gorgaslidze	PROPN
gs-3921	802	2	,	,	PUNCT
gs-3921	802	3	nana	nana	PROPN
gs-3921	802	4	,	,	PUNCT
gs-3921	802	5	nodar	nodar	NOUN
gs-3921	802	6	sulashvili	sulashvili	NOUN
gs-3921	802	7	,	,	PUNCT
gs-3921	802	8	luiza	luiza	PROPN
gs-3921	802	9	gabunia	gabunia	PROPN
gs-3921	802	10	,	,	PUNCT
gs-3921	802	11	levan	levan	PROPN
gs-3921	802	12	ratiani	ratiani	PROPN
gs-3921	802	13	,	,	PUNCT
gs-3921	802	14	and	and	CCONJ
gs-3921	802	15	marina	marina	PROPN
gs-3921	802	16	giorgobiani	giorgobiani	PROPN
gs-3921	802	17	.	.	PUNCT
gs-3921	803	1	2023	2023	NUM
gs-3921	803	2	.	.	PUNCT
gs-3921	804	1	“	"	PUNCT
gs-3921	804	2	the	the	DET
gs-3921	804	3	singularities	singularity	NOUN
gs-3921	804	4	of	of	ADP
gs-3921	804	5	temozolomide	temozolomide	NOUN
gs-3921	804	6	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	804	7	effects	effect	NOUN
gs-3921	804	8	in	in	ADP
gs-3921	804	9	brain	brain	NOUN
gs-3921	804	10	tumor	tumor	NOUN
gs-3921	804	11	therapeutic	therapeutic	ADJ
gs-3921	804	12	applications	application	NOUN
gs-3921	804	13	”	"	PUNCT
gs-3921	804	14	.	.	PUNCT
gs-3921	805	1	experimental	experimental	ADJ
gs-3921	805	2	and	and	CCONJ
gs-3921	805	3	clinical	clinical	ADJ
gs-3921	805	4	medicine	medicine	NOUN
gs-3921	805	5	georgia	georgia	PROPN
gs-3921	805	6	,	,	PUNCT
gs-3921	805	7	no	no	INTJ
gs-3921	805	8	.	.	NOUN
gs-3921	805	9	4	4	NUM
gs-3921	805	10	(	(	PUNCT
gs-3921	805	11	november):6266	november):6266	NOUN
gs-3921	805	12	.	.	PUNCT
gs-3921	806	1	https://doi.org/10.52340/jecm.2023.04.16	https://doi.org/10.52340/jecm.2023.04.16	NOUN
gs-3921	806	2	.	.	PUNCT
gs-3921	807	1	georgian	georgian	ADJ
gs-3921	807	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	807	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	807	4	ტ.	ტ.	VERB
gs-3921	807	5	7	7	NUM
gs-3921	807	6	n	n	PRON
gs-3921	807	7	3	3	NUM
gs-3921	807	8	,	,	PUNCT
gs-3921	807	9	2025	2025	NUM
gs-3921	807	10	259	259	NUM
gs-3921	807	11	34	34	NUM
gs-3921	807	12	.	.	PUNCT
gs-3921	808	1	sulashvili	sulashvili	NOUN
gs-3921	808	2	,	,	PUNCT
gs-3921	808	3	nodar	nodar	ADV
gs-3921	808	4	,	,	PUNCT
gs-3921	808	5	margarita	margarita	PROPN
gs-3921	808	6	beglaryan	beglaryan	PROPN
gs-3921	808	7	,	,	PUNCT
gs-3921	808	8	nana	nana	PROPN
gs-3921	808	9	gorgaslidze	gorgaslidze	PROPN
gs-3921	808	10	,	,	PUNCT
gs-3921	808	11	seyran	seyran	PROPN
gs-3921	808	12	kocharyan	kocharyan	PROPN
gs-3921	808	13	,	,	PUNCT
gs-3921	808	14	naira	naira	PROPN
gs-3921	808	15	chichoyan	chichoyan	PROPN
gs-3921	808	16	,	,	PUNCT
gs-3921	808	17	luiza	luiza	PROPN
gs-3921	808	18	gabunia	gabunia	PROPN
gs-3921	808	19	,	,	PUNCT
gs-3921	808	20	irine	irine	NOUN
gs-3921	808	21	zarnadze	zarnadze	PROPN
gs-3921	808	22	,	,	PUNCT
gs-3921	808	23	et	et	PROPN
gs-3921	808	24	al	al	PROPN
gs-3921	808	25	.	.	PROPN
gs-3921	808	26	2023	2023	NUM
gs-3921	808	27	.	.	PUNCT
gs-3921	809	1	“	"	PUNCT
gs-3921	809	2	the	the	DET
gs-3921	809	3	disclosure	disclosure	NOUN
gs-3921	809	4	of	of	ADP
gs-3921	809	5	features	feature	NOUN
gs-3921	809	6	,	,	PUNCT
gs-3921	809	7	characteristics	characteristic	NOUN
gs-3921	809	8	,	,	PUNCT
gs-3921	809	9	possibilities	possibility	NOUN
gs-3921	809	10	and	and	CCONJ
gs-3921	809	11	specialties	specialty	NOUN
gs-3921	809	12	of	of	ADP
gs-3921	809	13	clinical	clinical	ADJ
gs-3921	809	14	pharmacists	pharmacist	NOUN
gs-3921	809	15	as	as	ADP
gs-3921	809	16	mediator	mediator	NOUN
gs-3921	809	17	among	among	ADP
gs-3921	809	18	doctors	doctor	NOUN
gs-3921	809	19	and	and	CCONJ
gs-3921	809	20	patients	patient	NOUN
gs-3921	809	21	for	for	ADP
gs-3921	809	22	enhancement	enhancement	NOUN
gs-3921	809	23	public	public	ADJ
gs-3921	809	24	health	health	NOUN
gs-3921	809	25	sector	sector	NOUN
gs-3921	809	26	in	in	ADP
gs-3921	809	27	a	a	DET
gs-3921	809	28	global	global	ADJ
gs-3921	809	29	world	world	NOUN
gs-3921	809	30	”	"	PUNCT
gs-3921	809	31	.	.	PUNCT
gs-3921	810	1	experimental	experimental	ADJ
gs-3921	810	2	and	and	CCONJ
gs-3921	810	3	clinical	clinical	ADJ
gs-3921	810	4	medicine	medicine	NOUN
gs-3921	810	5	georgia	georgia	PROPN
gs-3921	810	6	,	,	PUNCT
gs-3921	810	7	no	no	INTJ
gs-3921	810	8	.	.	NOUN
gs-3921	810	9	4	4	NUM
gs-3921	810	10	(	(	PUNCT
gs-3921	810	11	november):57	november):57	NOUN
gs-3921	810	12	-	-	PUNCT
gs-3921	810	13	62	62	NUM
gs-3921	810	14	.	.	PUNCT
gs-3921	811	1	https://doi.org/10.52340/jecm.2023.04.15	https://doi.org/10.52340/jecm.2023.04.15	PROPN
gs-3921	811	2	.	.	PROPN
gs-3921	811	3	35	35	NUM
gs-3921	811	4	.	.	PUNCT
gs-3921	812	1	kvizhinadze	kvizhinadze	PROPN
gs-3921	812	2	,	,	PUNCT
gs-3921	812	3	natia	natia	PROPN
gs-3921	812	4	,	,	PUNCT
gs-3921	812	5	nino	nino	PROPN
gs-3921	812	6	intskirveli	intskirveli	PROPN
gs-3921	812	7	,	,	PUNCT
gs-3921	812	8	david	david	PROPN
gs-3921	812	9	topuria	topuria	PROPN
gs-3921	812	10	,	,	PUNCT
gs-3921	812	11	nana	nana	PROPN
gs-3921	812	12	dughashvili	dughashvili	NOUN
gs-3921	812	13	,	,	PUNCT
gs-3921	812	14	and	and	CCONJ
gs-3921	812	15	nodar	nodar	NOUN
gs-3921	812	16	sulashvili	sulashvili	NOUN
gs-3921	812	17	.	.	PUNCT
gs-3921	813	1	2023	2023	NUM
gs-3921	813	2	.	.	PUNCT
gs-3921	814	1	“	"	PUNCT
gs-3921	814	2	gsp	gsp	NOUN
gs-3921	814	3	and	and	CCONJ
gs-3921	814	4	its	its	PRON
gs-3921	814	5	features	feature	NOUN
gs-3921	814	6	in	in	ADP
gs-3921	814	7	medical	medical	ADJ
gs-3921	814	8	and	and	CCONJ
gs-3921	814	9	pharmaceutical	pharmaceutical	NOUN
gs-3921	814	10	institutions	institution	NOUN
gs-3921	814	11	”	"	PUNCT
gs-3921	814	12	.	.	PUNCT
gs-3921	815	1	experimental	experimental	ADJ
gs-3921	815	2	and	and	CCONJ
gs-3921	815	3	clinical	clinical	ADJ
gs-3921	815	4	medicine	medicine	NOUN
gs-3921	815	5	georgia	georgia	PROPN
gs-3921	815	6	,	,	PUNCT
gs-3921	815	7	no	no	INTJ
gs-3921	815	8	.	.	NOUN
gs-3921	815	9	4	4	NUM
gs-3921	815	10	(	(	PUNCT
gs-3921	815	11	november):17	november):17	NOUN
gs-3921	815	12	-	-	PUNCT
gs-3921	815	13	19	19	NUM
gs-3921	815	14	.	.	PUNCT
gs-3921	815	15	https://doi.org/10.52340/jecm.2023.04.03	https://doi.org/10.52340/jecm.2023.04.03	NUM
gs-3921	815	16	.	.	NOUN
gs-3921	816	1	36	36	NUM
gs-3921	816	2	.	.	PUNCT
gs-3921	816	3	sulashvili	sulashvili	NOUN
gs-3921	816	4	,	,	PUNCT
gs-3921	816	5	nodar	nodar	PROPN
gs-3921	816	6	,	,	PUNCT
gs-3921	816	7	nana	nana	PROPN
gs-3921	816	8	gorgaslidze	gorgaslidze	PROPN
gs-3921	816	9	,	,	PUNCT
gs-3921	816	10	margarita	margarita	PROPN
gs-3921	816	11	beglaryan	beglaryan	PROPN
gs-3921	816	12	,	,	PUNCT
gs-3921	816	13	luiza	luiza	PROPN
gs-3921	816	14	gabunia	gabunia	PROPN
gs-3921	816	15	,	,	PUNCT
gs-3921	816	16	naira	naira	PROPN
gs-3921	816	17	chichoyan	chichoyan	PROPN
gs-3921	816	18	,	,	PUNCT
gs-3921	816	19	marina	marina	PROPN
gs-3921	816	20	giorgobiani	giorgobiani	PROPN
gs-3921	816	21	,	,	PUNCT
gs-3921	816	22	irine	irine	NOUN
gs-3921	816	23	zarnadze	zarnadze	NOUN
gs-3921	816	24	,	,	PUNCT
gs-3921	816	25	and	and	CCONJ
gs-3921	816	26	shalva	shalva	PROPN
gs-3921	816	27	(	(	PUNCT
gs-3921	816	28	davit	davit	NOUN
gs-3921	816	29	)	)	PUNCT
gs-3921	816	30	zarnadze	zarnadze	NOUN
gs-3921	816	31	.	.	PUNCT
gs-3921	816	32	2022	2022	NUM
gs-3921	816	33	.	.	PUNCT
gs-3921	817	1	“	"	PUNCT
gs-3921	817	2	the	the	DET
gs-3921	817	3	scientific	scientific	ADJ
gs-3921	817	4	talks	talk	NOUN
gs-3921	817	5	of	of	ADP
gs-3921	817	6	essential	essential	ADJ
gs-3921	817	7	issue	issue	NOUN
gs-3921	817	8	,	,	PUNCT
gs-3921	817	9	invocation	invocation	NOUN
gs-3921	817	10	,	,	PUNCT
gs-3921	817	11	perspectives	perspective	NOUN
gs-3921	817	12	,	,	PUNCT
gs-3921	817	13	inclinations	inclination	NOUN
gs-3921	817	14	and	and	CCONJ
gs-3921	817	15	features	feature	NOUN
gs-3921	817	16	of	of	ADP
gs-3921	817	17	the	the	DET
gs-3921	817	18	clinical	clinical	ADJ
gs-3921	817	19	pharmacists	pharmacist	NOUN
gs-3921	817	20	globally	globally	ADV
gs-3921	817	21	”	"	PUNCT
gs-3921	817	22	.	.	PUNCT
gs-3921	818	1	experimental	experimental	ADJ
gs-3921	818	2	and	and	CCONJ
gs-3921	818	3	clinical	clinical	ADJ
gs-3921	818	4	medicine	medicine	NOUN
gs-3921	818	5	georgia	georgia	PROPN
gs-3921	818	6	,	,	PUNCT
gs-3921	818	7	no	no	INTJ
gs-3921	818	8	.	.	NOUN
gs-3921	818	9	7	7	NUM
gs-3921	818	10	(	(	PUNCT
gs-3921	818	11	october	october	PROPN
gs-3921	818	12	)	)	PUNCT
gs-3921	818	13	.	.	PUNCT
gs-3921	819	1	https://doi.org/10.52340/jecm.2022.07.09	https://doi.org/10.52340/jecm.2022.07.09	PROPN
gs-3921	819	2	.	.	PUNCT
gs-3921	820	1	37	37	NUM
gs-3921	820	2	.	.	PUNCT
gs-3921	821	1	sulashvili	sulashvili	NOUN
gs-3921	821	2	,	,	PUNCT
gs-3921	821	3	nodar	nodar	INTJ
gs-3921	821	4	,	,	PUNCT
gs-3921	821	5	margarita	margarita	PROPN
gs-3921	821	6	beglaryan	beglaryan	PROPN
gs-3921	821	7	,	,	PUNCT
gs-3921	821	8	nana	nana	PROPN
gs-3921	821	9	gorgaslidze	gorgaslidze	PROPN
gs-3921	821	10	,	,	PUNCT
gs-3921	821	11	seyran	seyran	PROPN
gs-3921	821	12	kocharyan	kocharyan	PROPN
gs-3921	821	13	,	,	PUNCT
gs-3921	821	14	naira	naira	PROPN
gs-3921	821	15	chichoyan	chichoyan	PROPN
gs-3921	821	16	,	,	PUNCT
gs-3921	821	17	luiza	luiza	PROPN
gs-3921	821	18	gabunia	gabunia	PROPN
gs-3921	821	19	,	,	PUNCT
gs-3921	821	20	natia	natia	PROPN
gs-3921	821	21	kvizhinadze	kvizhinadze	PROPN
gs-3921	821	22	,	,	PUNCT
gs-3921	821	23	marina	marina	PROPN
gs-3921	821	24	giorgobiani	giorgobiani	PROPN
gs-3921	821	25	,	,	PUNCT
gs-3921	821	26	irine	irine	NOUN
gs-3921	821	27	zarnadze	zarnadze	NOUN
gs-3921	821	28	,	,	PUNCT
gs-3921	821	29	and	and	CCONJ
gs-3921	821	30	shalva	shalva	PROPN
gs-3921	821	31	(	(	PUNCT
gs-3921	821	32	davit	davit	NOUN
gs-3921	821	33	)	)	PUNCT
gs-3921	821	34	zarnadze	zarnadze	NOUN
gs-3921	821	35	.	.	PUNCT
gs-3921	822	1	2022	2022	NUM
gs-3921	822	2	.	.	PUNCT
gs-3921	823	1	“	"	PUNCT
gs-3921	823	2	the	the	DET
gs-3921	823	3	scientific	scientific	ADJ
gs-3921	823	4	discussion	discussion	NOUN
gs-3921	823	5	of	of	ADP
gs-3921	823	6	specificities	specificity	NOUN
gs-3921	823	7	of	of	ADP
gs-3921	823	8	pharmacist	pharmacist	NOUN
gs-3921	823	9	occupational	occupational	ADJ
gs-3921	823	10	and	and	CCONJ
gs-3921	823	11	higher	high	ADJ
gs-3921	823	12	medical	medical	ADJ
gs-3921	823	13	-	-	PUNCT
gs-3921	823	14	pharmaceutical	pharmaceutical	ADJ
gs-3921	823	15	educational	educational	ADJ
gs-3921	823	16	manifestation	manifestation	NOUN
gs-3921	823	17	outlooks	outlook	NOUN
gs-3921	823	18	in	in	ADP
gs-3921	823	19	georgia	georgia	PROPN
gs-3921	823	20	”	"	PUNCT
gs-3921	823	21	.	.	PUNCT
gs-3921	824	1	experimental	experimental	ADJ
gs-3921	824	2	and	and	CCONJ
gs-3921	824	3	clinical	clinical	ADJ
gs-3921	824	4	medicine	medicine	NOUN
gs-3921	824	5	georgia	georgia	PROPN
gs-3921	824	6	,	,	PUNCT
gs-3921	824	7	no	no	INTJ
gs-3921	824	8	.	.	NOUN
gs-3921	824	9	7	7	NUM
gs-3921	824	10	(	(	PUNCT
gs-3921	824	11	october	october	PROPN
gs-3921	824	12	)	)	PUNCT
gs-3921	824	13	.	.	PUNCT
gs-3921	825	1	https://doi.org/10.52340/jecm.2022.07.08	https://doi.org/10.52340/jecm.2022.07.08	NUM
gs-3921	825	2	.	.	PUNCT
gs-3921	826	1	38	38	NUM
gs-3921	826	2	.	.	PUNCT
gs-3921	827	1	gorgaslidze	gorgaslidze	PROPN
gs-3921	827	2	,	,	PUNCT
gs-3921	827	3	nana	nana	PROPN
gs-3921	827	4	,	,	PUNCT
gs-3921	827	5	shafiga	shafiga	PROPN
gs-3921	827	6	topchiyeva	topchiyeva	PROPN
gs-3921	827	7	,	,	PUNCT
gs-3921	827	8	marina	marina	NOUN
gs-3921	827	9	giorgobiani	giorgobiani	PROPN
gs-3921	827	10	,	,	PUNCT
gs-3921	827	11	and	and	CCONJ
gs-3921	827	12	nodar	nodar	NOUN
gs-3921	827	13	sulashvili	sulashvili	NOUN
gs-3921	827	14	.	.	PUNCT
gs-3921	828	1	2022	2022	NUM
gs-3921	828	2	.	.	PUNCT
gs-3921	829	1	“	"	PUNCT
gs-3921	829	2	the	the	DET
gs-3921	829	3	impact	impact	NOUN
gs-3921	829	4	of	of	ADP
gs-3921	829	5	pharmaceutical	pharmaceutical	ADJ
gs-3921	829	6	marketing	marketing	NOUN
gs-3921	829	7	on	on	ADP
gs-3921	829	8	the	the	DET
gs-3921	829	9	society	society	NOUN
gs-3921	829	10	and	and	CCONJ
gs-3921	829	11	individual	individual	ADJ
gs-3921	829	12	patient	patient	NOUN
gs-3921	829	13	and	and	CCONJ
gs-3921	829	14	its	its	PRON
gs-3921	829	15	specification	specification	NOUN
gs-3921	829	16	of	of	ADP
gs-3921	829	17	handling	handling	NOUN
gs-3921	829	18	”	"	PUNCT
gs-3921	829	19	.	.	PUNCT
gs-3921	830	1	experimental	experimental	ADJ
gs-3921	830	2	and	and	CCONJ
gs-3921	830	3	clinical	clinical	ADJ
gs-3921	830	4	medicine	medicine	NOUN
gs-3921	830	5	georgia	georgia	PROPN
gs-3921	830	6	,	,	PUNCT
gs-3921	830	7	no	no	INTJ
gs-3921	830	8	.	.	NOUN
gs-3921	830	9	7	7	NUM
gs-3921	830	10	(	(	PUNCT
gs-3921	830	11	october	october	PROPN
gs-3921	830	12	)	)	PUNCT
gs-3921	830	13	.	.	PUNCT
gs-3921	831	1	https://doi.org/10.52340/jecm.2022.07.07	https://doi.org/10.52340/jecm.2022.07.07	X
gs-3921	831	2	.	.	PROPN
gs-3921	832	1	39	39	NUM
gs-3921	832	2	.	.	PUNCT
gs-3921	833	1	gorgaslidze	gorgaslidze	PROPN
gs-3921	833	2	,	,	PUNCT
gs-3921	833	3	nana	nana	PROPN
gs-3921	833	4	,	,	PUNCT
gs-3921	833	5	and	and	CCONJ
gs-3921	833	6	nodar	nodar	NOUN
gs-3921	833	7	sulashvili	sulashvili	NOUN
gs-3921	833	8	.	.	PUNCT
gs-3921	834	1	2022	2022	NUM
gs-3921	834	2	.	.	PUNCT
gs-3921	835	1	“	"	PUNCT
gs-3921	835	2	the	the	DET
gs-3921	835	3	features	feature	NOUN
gs-3921	835	4	of	of	ADP
gs-3921	835	5	the	the	DET
gs-3921	835	6	pharmaceutical	pharmaceutical	ADJ
gs-3921	835	7	market	market	NOUN
gs-3921	835	8	and	and	CCONJ
gs-3921	835	9	its	its	PRON
gs-3921	835	10	outlooks	outlook	NOUN
gs-3921	835	11	in	in	ADP
gs-3921	835	12	georgia	georgia	PROPN
gs-3921	835	13	”	"	PUNCT
gs-3921	835	14	.	.	PUNCT
gs-3921	836	1	experimental	experimental	ADJ
gs-3921	836	2	and	and	CCONJ
gs-3921	836	3	clinical	clinical	ADJ
gs-3921	836	4	medicine	medicine	NOUN
gs-3921	836	5	georgia	georgia	PROPN
gs-3921	836	6	,	,	PUNCT
gs-3921	836	7	no	no	INTJ
gs-3921	836	8	.	.	NOUN
gs-3921	836	9	7	7	NUM
gs-3921	836	10	(	(	PUNCT
gs-3921	836	11	october	october	PROPN
gs-3921	836	12	)	)	PUNCT
gs-3921	836	13	.	.	PUNCT
gs-3921	837	1	https://doi.org/10.52340/jecm.2022.07.06	https://doi.org/10.52340/jecm.2022.07.06	PROPN
gs-3921	837	2	.	.	PUNCT
gs-3921	838	1	40	40	NUM
gs-3921	838	2	.	.	PUNCT
gs-3921	839	1	natia	natia	PROPN
gs-3921	839	2	kvizhinadze	kvizhinadze	PROPN
gs-3921	839	3	,	,	PUNCT
gs-3921	839	4	nana	nana	PROPN
gs-3921	839	5	dughashvili	dughashvili	NOUN
gs-3921	839	6	,	,	PUNCT
gs-3921	839	7	tamaz	tamaz	DET
gs-3921	839	8	tchumburidze	tchumburidze	PROPN
gs-3921	839	9	,	,	PUNCT
gs-3921	839	10	david	david	PROPN
gs-3921	839	11	topuria	topuria	PROPN
gs-3921	839	12	,	,	PUNCT
gs-3921	839	13	nodar	nodar	NOUN
gs-3921	839	14	sulashvili	sulashvili	NOUN
gs-3921	839	15	.	.	PUNCT
gs-3921	840	1	proper	proper	ADJ
gs-3921	840	2	practice	practice	NOUN
gs-3921	840	3	of	of	ADP
gs-3921	840	4	prescribing	prescribe	VERB
gs-3921	840	5	medications	medication	NOUN
gs-3921	840	6	in	in	ADP
gs-3921	840	7	georgia	georgia	PROPN
gs-3921	840	8	.	.	PUNCT
gs-3921	841	1	jecmg	jecmg	PROPN
gs-3921	842	1	[	[	X
gs-3921	842	2	internet	internet	NOUN
gs-3921	842	3	]	]	PUNCT
gs-3921	842	4	.	.	PUNCT
gs-3921	843	1	2021	2021	NUM
gs-3921	843	2	oct	oct	PROPN
gs-3921	843	3	.	.	PROPN
gs-3921	843	4	19	19	NUM
gs-3921	844	1	[	[	X
gs-3921	844	2	cited	cite	VERB
gs-3921	844	3	2025	2025	NUM
gs-3921	844	4	jul	jul	PROPN
gs-3921	844	5	.	.	PUNCT
gs-3921	845	1	12];(5	12];(5	NUM
gs-3921	845	2	-	-	PUNCT
gs-3921	845	3	6	6	NUM
gs-3921	845	4	)	)	PUNCT
gs-3921	845	5	.	.	PUNCT
gs-3921	846	1	available	available	ADJ
gs-3921	846	2	from	from	ADP
gs-3921	846	3	:	:	PUNCT
gs-3921	846	4	https://journals.4science.ge/index.php/jecm/article/view/597	https://journals.4science.ge/index.php/jecm/article/view/597	PROPN
gs-3921	846	5	.	.	PROPN
gs-3921	846	6	41	41	NUM
gs-3921	846	7	.	.	PUNCT
gs-3921	847	1	nana	nana	PROPN
gs-3921	847	2	gorgaslidze	gorgaslidze	PROPN
gs-3921	847	3	,	,	PUNCT
gs-3921	847	4	nodar	nodar	NOUN
gs-3921	847	5	sulashvili	sulashvili	NOUN
gs-3921	847	6	,	,	PUNCT
gs-3921	847	7	marina	marina	NOUN
gs-3921	847	8	giorgobiani	giorgobiani	PROPN
gs-3921	847	9	,	,	PUNCT
gs-3921	847	10	tea	tea	NOUN
gs-3921	847	11	zarkua	zarkua	NOUN
gs-3921	847	12	,	,	PUNCT
gs-3921	847	13	nana	nana	PROPN
gs-3921	847	14	dugashvili	dugashvili	PROPN
gs-3921	847	15	.	.	PUNCT
gs-3921	848	1	the	the	DET
gs-3921	848	2	features	feature	NOUN
gs-3921	848	3	of	of	ADP
gs-3921	848	4	inspection	inspection	NOUN
gs-3921	848	5	and	and	CCONJ
gs-3921	848	6	monitoring	monitoring	NOUN
gs-3921	848	7	framework	framework	NOUN
gs-3921	848	8	for	for	ADP
gs-3921	848	9	professional	professional	ADJ
gs-3921	848	10	safety	safety	NOUN
gs-3921	848	11	,	,	PUNCT
gs-3921	848	12	sanitary	sanitary	NOUN
gs-3921	848	13	,	,	PUNCT
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gs-3921	848	15	scientists/ქართველი	scientists/ქართველი	NOUN
gs-3921	848	16	მეცნიერები	მეცნიერები	NOUN
gs-3921	848	17	ტ.	ტ.	VERB
gs-3921	848	18	7	7	NUM
gs-3921	848	19	n	n	PRON
gs-3921	848	20	3	3	NUM
gs-3921	848	21	,	,	PUNCT
gs-3921	848	22	2025	2025	NUM
gs-3921	848	23	260	260	NUM
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gs-3921	848	25	,	,	PUNCT
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gs-3921	848	27	and	and	CCONJ
gs-3921	848	28	hygienic	hygienic	ADJ
gs-3921	848	29	novel	novel	ADJ
gs-3921	848	30	requirement	requirement	NOUN
gs-3921	848	31	issues	issue	NOUN
gs-3921	848	32	of	of	ADP
gs-3921	848	33	pharmaceutical	pharmaceutical	ADJ
gs-3921	848	34	organizations	organization	NOUN
gs-3921	848	35	in	in	ADP
gs-3921	848	36	the	the	DET
gs-3921	848	37	context	context	NOUN
gs-3921	848	38	of	of	ADP
gs-3921	848	39	the	the	DET
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gs-3921	848	41	pandemic	pandemic	NOUN
gs-3921	848	42	in	in	ADP
gs-3921	848	43	georgia	georgia	PROPN
gs-3921	848	44	.	.	PUNCT
gs-3921	849	1	jecmg	jecmg	PROPN
gs-3921	850	1	[	[	X
gs-3921	850	2	internet	internet	NOUN
gs-3921	850	3	]	]	PUNCT
gs-3921	850	4	.	.	PUNCT
gs-3921	851	1	2021	2021	NUM
gs-3921	851	2	oct	oct	PROPN
gs-3921	851	3	.	.	PROPN
gs-3921	851	4	19	19	NUM
gs-3921	852	1	[	[	X
gs-3921	852	2	cited	cite	VERB
gs-3921	852	3	2025	2025	NUM
gs-3921	852	4	jul	jul	PROPN
gs-3921	852	5	.	.	PUNCT
gs-3921	852	6	12];(5	12];(5	PROPN
gs-3921	852	7	-	-	PUNCT
gs-3921	852	8	6):426	6):426	NUM
gs-3921	852	9	.	.	PUNCT
gs-3921	853	1	available	available	ADJ
gs-3921	853	2	from	from	ADP
gs-3921	853	3	:	:	PUNCT
gs-3921	853	4	https://journals.4science.ge/index.php/jecm/article/view/576	https://journals.4science.ge/index.php/jecm/article/view/576	PROPN
gs-3921	853	5	.	.	PUNCT
gs-3921	854	1	42	42	NUM
gs-3921	854	2	.	.	PUNCT
gs-3921	854	3	sulashvili	sulashvili	NOUN
gs-3921	854	4	,	,	PUNCT
gs-3921	854	5	nodar	nodar	ADV
gs-3921	854	6	,	,	PUNCT
gs-3921	854	7	artashes	artashe	VERB
gs-3921	854	8	aznauryan	aznauryan	PROPN
gs-3921	854	9	,	,	PUNCT
gs-3921	854	10	anna	anna	PROPN
gs-3921	854	11	ter	ter	NOUN
gs-3921	854	12	-	-	PUNCT
gs-3921	854	13	markosyan	markosyan	ADJ
gs-3921	854	14	,	,	PUNCT
gs-3921	854	15	nana	nana	PROPN
gs-3921	854	16	gorgaslidze	gorgaslidze	PROPN
gs-3921	854	17	,	,	PUNCT
gs-3921	854	18	seyran	seyran	PROPN
gs-3921	854	19	kocharyan	kocharyan	PROPN
gs-3921	854	20	,	,	PUNCT
gs-3921	854	21	irine	irine	PROPN
gs-3921	854	22	zarnadze	zarnadze	PROPN
gs-3921	854	23	,	,	PUNCT
gs-3921	854	24	bagrat	bagrat	NOUN
gs-3921	854	25	yenokyan	yenokyan	PROPN
gs-3921	854	26	,	,	PUNCT
gs-3921	854	27	et	et	PROPN
gs-3921	854	28	al	al	PROPN
gs-3921	854	29	.	.	PROPN
gs-3921	854	30	2021	2021	NUM
gs-3921	854	31	.	.	PUNCT
gs-3921	855	1	“	"	PUNCT
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gs-3921	855	4	discussion	discussion	NOUN
gs-3921	855	5	of	of	ADP
gs-3921	855	6	specificites	specificite	NOUN
gs-3921	855	7	of	of	ADP
gs-3921	855	8	the	the	DET
gs-3921	855	9	role	role	NOUN
gs-3921	855	10	,	,	PUNCT
gs-3921	855	11	achievements	achievement	NOUN
gs-3921	855	12	,	,	PUNCT
gs-3921	855	13	innovations	innovation	NOUN
gs-3921	855	14	,	,	PUNCT
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gs-3921	855	16	and	and	CCONJ
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gs-3921	855	18	prospects	prospect	NOUN
gs-3921	855	19	of	of	ADP
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gs-3921	855	21	in	in	ADP
gs-3921	855	22	the	the	DET
gs-3921	855	23	context	context	NOUN
gs-3921	855	24	of	of	ADP
gs-3921	855	25	the	the	DET
gs-3921	855	26	development	development	NOUN
gs-3921	855	27	of	of	ADP
gs-3921	855	28	health	health	NOUN
gs-3921	855	29	care	care	NOUN
gs-3921	855	30	sector	sector	NOUN
gs-3921	855	31	globally	globally	ADV
gs-3921	855	32	”	"	PUNCT
gs-3921	855	33	.	.	PUNCT
gs-3921	856	1	experimental	experimental	ADJ
gs-3921	856	2	and	and	CCONJ
gs-3921	856	3	clinical	clinical	ADJ
gs-3921	856	4	medicine	medicine	NOUN
gs-3921	856	5	georgia	georgia	PROPN
gs-3921	856	6	,	,	PUNCT
gs-3921	856	7	no	no	INTJ
gs-3921	856	8	.	.	NOUN
gs-3921	856	9	5	5	NUM
gs-3921	856	10	-	-	SYM
gs-3921	856	11	6	6	NUM
gs-3921	856	12	(	(	PUNCT
gs-3921	856	13	october	october	PROPN
gs-3921	856	14	):	):	PUNCT
gs-3921	856	15	38	38	NUM
gs-3921	856	16	-	-	SYM
gs-3921	856	17	41	41	NUM
gs-3921	856	18	.	.	PUNCT
gs-3921	857	1	https://journals.4science.ge/index.php/jecm/article/view/575	https://journals.4science.ge/index.php/jecm/article/view/575	PROPN
gs-3921	857	2	.	.	PUNCT
gs-3921	858	1	43	43	NUM
gs-3921	858	2	.	.	PUNCT
gs-3921	859	1	aphkhazava	aphkhazava	PROPN
gs-3921	859	2	,	,	PUNCT
gs-3921	859	3	david	david	PROPN
gs-3921	859	4	,	,	PUNCT
gs-3921	859	5	nodar	nodar	NOUN
gs-3921	859	6	sulashvili	sulashvili	NOUN
gs-3921	859	7	,	,	PUNCT
gs-3921	859	8	and	and	CCONJ
gs-3921	859	9	jaba	jaba	PROPN
gs-3921	859	10	tkemaladze	tkemaladze	PROPN
gs-3921	859	11	.	.	PUNCT
gs-3921	860	1	2025	2025	NUM
gs-3921	860	2	.	.	PUNCT
gs-3921	861	1	“	"	PUNCT
gs-3921	861	2	stem	stem	NOUN
gs-3921	861	3	cell	cell	NOUN
gs-3921	861	4	systems	system	NOUN
gs-3921	861	5	and	and	CCONJ
gs-3921	861	6	regeneration	regeneration	NOUN
gs-3921	861	7	”	"	PUNCT
gs-3921	861	8	.	.	PUNCT
gs-3921	862	1	georgian	georgian	PROPN
gs-3921	862	2	scientists	scientist	NOUN
gs-3921	862	3	7	7	NUM
gs-3921	862	4	(	(	PUNCT
gs-3921	862	5	1):271	1):271	NUM
gs-3921	862	6	-	-	SYM
gs-3921	862	7	319	319	NUM
gs-3921	862	8	.	.	PUNCT
gs-3921	863	1	https://doi.org/10.52340/gs.2025.07.01.26	https://doi.org/10.52340/gs.2025.07.01.26	NOUN
gs-3921	863	2	.	.	PROPN
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gs-3921	863	4	.	.	PUNCT
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gs-3921	864	7	,	,	PUNCT
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gs-3921	864	10	,	,	PUNCT
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gs-3921	864	13	,	,	PUNCT
gs-3921	864	14	shorena	shorena	PROPN
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gs-3921	864	17	vira	vira	PROPN
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gs-3921	864	19	,	,	PUNCT
gs-3921	864	20	igor	igor	PROPN
gs-3921	864	21	seniuk	seniuk	NOUN
gs-3921	864	22	,	,	PUNCT
gs-3921	864	23	marina	marina	PROPN
gs-3921	864	24	giorgobiani	giorgobiani	PROPN
gs-3921	864	25	,	,	PUNCT
gs-3921	864	26	natia	natia	PROPN
gs-3921	864	27	kvizhinadze	kvizhinadze	PROPN
gs-3921	864	28	,	,	PUNCT
gs-3921	864	29	and	and	CCONJ
gs-3921	864	30	marika	marika	PROPN
gs-3921	864	31	sulashvili	sulashvili	PROPN
gs-3921	864	32	.	.	PUNCT
gs-3921	865	1	2024	2024	NUM
gs-3921	865	2	.	.	PUNCT
gs-3921	866	1	“	"	PUNCT
gs-3921	866	2	manifestation	manifestation	NOUN
gs-3921	866	3	of	of	ADP
gs-3921	866	4	the	the	DET
gs-3921	866	5	particularities	particularity	NOUN
gs-3921	866	6	of	of	ADP
gs-3921	866	7	some	some	DET
gs-3921	866	8	key	key	ADJ
gs-3921	866	9	issue	issue	NOUN
gs-3921	866	10	aspects	aspect	NOUN
gs-3921	866	11	of	of	ADP
gs-3921	866	12	new	new	ADJ
gs-3921	866	13	immunotherapy	immunotherapy	NOUN
gs-3921	866	14	challenges	challenge	NOUN
gs-3921	866	15	and	and	CCONJ
gs-3921	866	16	perspectives	perspective	NOUN
gs-3921	866	17	by	by	ADP
gs-3921	866	18	car	car	NOUN
gs-3921	866	19	-	-	PUNCT
gs-3921	866	20	t	t	NOUN
gs-3921	866	21	cell	cell	NOUN
gs-3921	866	22	therapy	therapy	NOUN
gs-3921	866	23	”	"	PUNCT
gs-3921	866	24	.	.	PUNCT
gs-3921	867	1	experimental	experimental	ADJ
gs-3921	867	2	and	and	CCONJ
gs-3921	867	3	clinical	clinical	ADJ
gs-3921	867	4	medicine	medicine	NOUN
gs-3921	867	5	georgia	georgia	PROPN
gs-3921	867	6	,	,	PUNCT
gs-3921	867	7	no	no	INTJ
gs-3921	867	8	.	.	NOUN
gs-3921	867	9	4	4	NUM
gs-3921	867	10	(	(	PUNCT
gs-3921	867	11	september):119	september):119	PROPN
gs-3921	867	12	-	-	PUNCT
gs-3921	867	13	21	21	NUM
gs-3921	867	14	.	.	PUNCT
gs-3921	868	1	https://doi.org/10.52340/jecm.2024.04.32	https://doi.org/10.52340/jecm.2024.04.32	NUM
gs-3921	868	2	.	.	PROPN
gs-3921	869	1	45	45	NUM
gs-3921	869	2	.	.	PUNCT
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gs-3921	869	4	,	,	PUNCT
gs-3921	869	5	nodar	nodar	INTJ
gs-3921	869	6	,	,	PUNCT
gs-3921	869	7	sharon	sharon	PROPN
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gs-3921	869	9	,	,	PUNCT
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gs-3921	869	12	-	-	PUNCT
gs-3921	869	13	hakeem	hakeem	PROPN
gs-3921	869	14	,	,	PUNCT
gs-3921	869	15	luiza	luiza	PROPN
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gs-3921	869	17	,	,	PUNCT
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gs-3921	869	22	beglaryan	beglaryan	PROPN
gs-3921	869	23	,	,	PUNCT
gs-3921	869	24	lali	lali	PROPN
gs-3921	869	25	patsia	patsia	PROPN
gs-3921	869	26	,	,	PUNCT
gs-3921	869	27	natia	natia	PROPN
gs-3921	869	28	kvizhinadze	kvizhinadze	PROPN
gs-3921	869	29	,	,	PUNCT
gs-3921	869	30	and	and	CCONJ
gs-3921	869	31	marika	marika	PROPN
gs-3921	869	32	sulashvili	sulashvili	PROPN
gs-3921	869	33	.	.	PUNCT
gs-3921	870	1	2025	2025	NUM
gs-3921	870	2	.	.	PUNCT
gs-3921	871	1	“	"	PUNCT
gs-3921	871	2	closed	close	VERB
gs-3921	871	3	-	-	PUNCT
gs-3921	871	4	loop	loop	NOUN
gs-3921	871	5	cardiopulmonary	cardiopulmonary	ADJ
gs-3921	871	6	bypass	bypass	NOUN
gs-3921	871	7	systems	system	NOUN
gs-3921	871	8	with	with	ADP
gs-3921	871	9	real	real	ADJ
gs-3921	871	10	-	-	PUNCT
gs-3921	871	11	time	time	NOUN
gs-3921	871	12	monitoring	monitoring	NOUN
gs-3921	871	13	and	and	CCONJ
gs-3921	871	14	pharmacotherapy	pharmacotherapy	NOUN
gs-3921	871	15	strategies	strategy	NOUN
gs-3921	871	16	:	:	PUNCT
gs-3921	871	17	innovations	innovation	NOUN
gs-3921	871	18	,	,	PUNCT
gs-3921	871	19	outcomes	outcome	NOUN
gs-3921	871	20	,	,	PUNCT
gs-3921	871	21	clinical	clinical	ADJ
gs-3921	871	22	impact	impact	NOUN
gs-3921	871	23	and	and	CCONJ
gs-3921	871	24	future	future	ADJ
gs-3921	871	25	directions	direction	NOUN
gs-3921	871	26	in	in	ADP
gs-3921	871	27	general	general	ADJ
gs-3921	871	28	”	"	PUNCT
gs-3921	871	29	.	.	PUNCT
gs-3921	872	1	georgian	georgian	PROPN
gs-3921	872	2	scientists	scientist	NOUN
gs-3921	872	3	7	7	NUM
gs-3921	872	4	(	(	PUNCT
gs-3921	872	5	2):381	2):381	PROPN
gs-3921	872	6	-	-	PUNCT
gs-3921	872	7	419	419	NUM
gs-3921	872	8	.	.	PUNCT
gs-3921	872	9	https://doi.org/10.52340/gs.2025.07.02.36	https://doi.org/10.52340/gs.2025.07.02.36	NUM
gs-3921	872	10	.	.	PUNCT
gs-3921	873	1	46	46	NUM
gs-3921	873	2	.	.	PUNCT
gs-3921	874	1	sulashvili	sulashvili	PROPN
gs-3921	874	2	n	n	PROPN
gs-3921	874	3	,	,	PUNCT
gs-3921	874	4	jadhav	jadhav	PROPN
gs-3921	874	5	rd	rd	PROPN
gs-3921	874	6	,	,	PUNCT
gs-3921	874	7	beglaryan	beglaryan	PROPN
gs-3921	874	8	m	m	PROPN
gs-3921	874	9	,	,	PUNCT
gs-3921	874	10	gabunia	gabunia	NOUN
gs-3921	874	11	l	l	NOUN
gs-3921	874	12	,	,	PUNCT
gs-3921	874	13	gorgaslidze	gorgaslidze	ADJ
gs-3921	874	14	n	n	CCONJ
gs-3921	874	15	,	,	PUNCT
gs-3921	874	16	alavidze	alavidze	PROPN
gs-3921	874	17	n	n	CCONJ
gs-3921	874	18	,	,	PUNCT
gs-3921	874	19	et	et	PROPN
gs-3921	874	20	al	al	PROPN
gs-3921	874	21	.	.	PUNCT
gs-3921	875	1	the	the	DET
gs-3921	875	2	scientific	scientific	ADJ
gs-3921	875	3	discussion	discussion	NOUN
gs-3921	875	4	of	of	ADP
gs-3921	875	5	key	key	ADJ
gs-3921	875	6	issue	issue	NOUN
gs-3921	875	7	aspects	aspect	NOUN
gs-3921	875	8	of	of	ADP
gs-3921	875	9	immunopathogenesis	immunopathogenesis	NOUN
gs-3921	875	10	and	and	CCONJ
gs-3921	875	11	pharmacological	pharmacological	NOUN
gs-3921	875	12	properties	property	NOUN
gs-3921	875	13	and	and	CCONJ
gs-3921	875	14	profiles	profile	NOUN
gs-3921	875	15	in	in	ADP
gs-3921	875	16	relation	relation	NOUN
gs-3921	875	17	to	to	ADP
gs-3921	875	18	adverse	adverse	ADJ
gs-3921	875	19	drug	drug	NOUN
gs-3921	875	20	reactions	reaction	NOUN
gs-3921	875	21	challenges	challenge	NOUN
gs-3921	875	22	,	,	PUNCT
gs-3921	875	23	focus	focus	VERB
gs-3921	875	24	on	on	ADP
gs-3921	875	25	multidimensional	multidimensional	ADJ
gs-3921	875	26	drug	drug	NOUN
gs-3921	875	27	-	-	PUNCT
gs-3921	875	28	induced	induce	VERB
gs-3921	875	29	eosinophilia	eosinophilia	NOUN
gs-3921	875	30	and	and	CCONJ
gs-3921	875	31	systemic	systemic	ADJ
gs-3921	875	32	syndrome	syndrome	NOUN
gs-3921	875	33	.	.	PUNCT
gs-3921	876	1	gs	gs	X
gs-3921	877	1	[	[	X
gs-3921	877	2	internet	internet	NOUN
gs-3921	877	3	]	]	X
gs-3921	877	4	.	.	PUNCT
gs-3921	878	1	2025	2025	NUM
gs-3921	878	2	jul	jul	NOUN
gs-3921	878	3	.	.	PROPN
gs-3921	878	4	11	11	NUM
gs-3921	879	1	[	[	X
gs-3921	879	2	cited	cite	VERB
gs-3921	879	3	2025	2025	NUM
gs-3921	879	4	jul	jul	PROPN
gs-3921	879	5	.	.	PUNCT
gs-3921	880	1	12];7(3):141	12];7(3):141	NUM
gs-3921	880	2	-	-	SYM
gs-3921	880	3	79	79	NUM
gs-3921	880	4	.	.	PUNCT
gs-3921	881	1	available	available	ADJ
gs-3921	881	2	from	from	ADP
gs-3921	881	3	:	:	PUNCT
gs-3921	881	4	https://journals.4science.ge/index.php/gs/article/view/3919	https://journals.4science.ge/index.php/gs/article/view/3919	NOUN
gs-3921	881	5	.	.	PUNCT
gs-3921	881	6	47	47	NUM
gs-3921	881	7	.	.	PUNCT
gs-3921	882	1	sulashvili	sulashvili	NOUN
gs-3921	882	2	,	,	PUNCT
gs-3921	882	3	nodar	nodar	INTJ
gs-3921	882	4	,	,	PUNCT
gs-3921	882	5	nato	nato	PROPN
gs-3921	882	6	alavidze	alavidze	PROPN
gs-3921	882	7	,	,	PUNCT
gs-3921	882	8	maka	maka	PROPN
gs-3921	882	9	buleishvili	buleishvili	PROPN
gs-3921	882	10	,	,	PUNCT
gs-3921	882	11	vira	vira	PROPN
gs-3921	882	12	kravchenko	kravchenko	PROPN
gs-3921	882	13	,	,	PUNCT
gs-3921	882	14	marika	marika	PROPN
gs-3921	882	15	sulashvili	sulashvili	PROPN
gs-3921	882	16	,	,	PUNCT
gs-3921	882	17	igor	igor	NOUN
gs-3921	882	18	seniuk	seniuk	NOUN
gs-3921	882	19	,	,	PUNCT
gs-3921	882	20	tamar	tamar	PROPN
gs-3921	882	21	okropiridze	okropiridze	PROPN
gs-3921	882	22	,	,	PUNCT
gs-3921	882	23	marina	marina	PROPN
gs-3921	882	24	giorgobiani	giorgobiani	PROPN
gs-3921	882	25	,	,	PUNCT
gs-3921	882	26	lela	lela	PROPN
gs-3921	882	27	grigolia	grigolia	PROPN
gs-3921	882	28	,	,	PUNCT
gs-3921	882	29	and	and	CCONJ
gs-3921	882	30	kakhaber	kakhaber	PROPN
gs-3921	882	31	robakidze	robakidze	NOUN
gs-3921	882	32	.	.	PUNCT
gs-3921	883	1	2025	2025	NUM
gs-3921	883	2	.	.	PUNCT
gs-3921	884	1	“	"	PUNCT
gs-3921	884	2	the	the	DET
gs-3921	884	3	manifestation	manifestation	NOUN
gs-3921	884	4	of	of	ADP
gs-3921	884	5	key	key	ADJ
gs-3921	884	6	issue	issue	NOUN
gs-3921	884	7	features	feature	NOUN
gs-3921	884	8	of	of	ADP
gs-3921	884	9	global	global	ADJ
gs-3921	884	10	perspectives	perspective	NOUN
gs-3921	884	11	on	on	ADP
gs-3921	884	12	innovative	innovative	ADJ
gs-3921	884	13	teaching	teaching	NOUN
gs-3921	884	14	and	and	CCONJ
gs-3921	884	15	learning	learn	VERB
gs-3921	884	16	approach	approach	NOUN
gs-3921	884	17	strategies	strategy	NOUN
gs-3921	884	18	in	in	ADP
gs-3921	884	19	higher	high	ADJ
gs-3921	884	20	medical	medical	ADJ
gs-3921	884	21	education	education	NOUN
gs-3921	884	22	:	:	PUNCT
gs-3921	884	23	advancing	advance	VERB
gs-3921	884	24	student	student	NOUN
gs-3921	884	25	georgian	georgian	PROPN
gs-3921	884	26	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	884	27	მეცნიერები	მეცნიერები	NOUN
gs-3921	884	28	ტ.	ტ.	VERB
gs-3921	884	29	7	7	NUM
gs-3921	884	30	n	n	PRON
gs-3921	884	31	3	3	NUM
gs-3921	884	32	,	,	PUNCT
gs-3921	884	33	2025	2025	NUM
gs-3921	884	34	261	261	NUM
gs-3921	884	35	centered	center	VERB
gs-3921	884	36	practices	practice	NOUN
gs-3921	884	37	,	,	PUNCT
gs-3921	884	38	technology	technology	NOUN
gs-3921	884	39	integration	integration	NOUN
gs-3921	884	40	and	and	CCONJ
gs-3921	884	41	competencybased	competencybase	VERB
gs-3921	884	42	frameworks	framework	NOUN
gs-3921	884	43	”	"	PUNCT
gs-3921	884	44	.	.	PUNCT
gs-3921	885	1	scientific	scientific	ADJ
gs-3921	885	2	journal	journal	NOUN
gs-3921	885	3	„	„	PUNCT
gs-3921	885	4	spectri	spectri	ADJ
gs-3921	885	5	“	"	PUNCT
gs-3921	885	6	10	10	NUM
gs-3921	885	7	(	(	PUNCT
gs-3921	885	8	2	2	NUM
gs-3921	885	9	)	)	PUNCT
gs-3921	885	10	.	.	PUNCT
gs-3921	886	1	https://doi.org/10.52340/spectri.2024.10.01.11	https://doi.org/10.52340/spectri.2024.10.01.11	X
gs-3921	886	2	.	.	PUNCT
gs-3921	887	1	48	48	NUM
gs-3921	887	2	.	.	PUNCT
gs-3921	888	1	sulashvili	sulashvili	NOUN
gs-3921	888	2	,	,	PUNCT
gs-3921	888	3	nodar	nodar	PROPN
gs-3921	888	4	,	,	PUNCT
gs-3921	888	5	nana	nana	PROPN
gs-3921	888	6	gorgaslidze	gorgaslidze	PROPN
gs-3921	888	7	,	,	PUNCT
gs-3921	888	8	margarita	margarita	PROPN
gs-3921	888	9	beglaryan	beglaryan	PROPN
gs-3921	888	10	,	,	PUNCT
gs-3921	888	11	luiza	luiza	PROPN
gs-3921	888	12	gabunia	gabunia	PROPN
gs-3921	888	13	,	,	PUNCT
gs-3921	888	14	natia	natia	PROPN
gs-3921	888	15	kvizhinadze	kvizhinadze	PROPN
gs-3921	888	16	,	,	PUNCT
gs-3921	888	17	tea	tea	NOUN
gs-3921	888	18	zarkua	zarkua	NOUN
gs-3921	888	19	,	,	PUNCT
gs-3921	888	20	marina	marina	NOUN
gs-3921	888	21	giorgobiani	giorgobiani	PROPN
gs-3921	888	22	,	,	PUNCT
gs-3921	888	23	nana	nana	PROPN
gs-3921	888	24	peikrishvili	peikrishvili	NOUN
gs-3921	888	25	,	,	PUNCT
gs-3921	888	26	and	and	CCONJ
gs-3921	888	27	marika	marika	PROPN
gs-3921	888	28	sulashvili	sulashvili	PROPN
gs-3921	888	29	.	.	PUNCT
gs-3921	889	1	2024	2024	NUM
gs-3921	889	2	.	.	PUNCT
gs-3921	890	1	“	"	PUNCT
gs-3921	890	2	the	the	DET
gs-3921	890	3	manifestation	manifestation	NOUN
gs-3921	890	4	of	of	ADP
gs-3921	890	5	characteristics	characteristic	NOUN
gs-3921	890	6	,	,	PUNCT
gs-3921	890	7	opportunities	opportunity	NOUN
gs-3921	890	8	and	and	CCONJ
gs-3921	890	9	challenges	challenge	NOUN
gs-3921	890	10	of	of	ADP
gs-3921	890	11	electronic	electronic	ADJ
gs-3921	890	12	systems	system	NOUN
gs-3921	890	13	and	and	CCONJ
gs-3921	890	14	digital	digital	ADJ
gs-3921	890	15	intelligence	intelligence	NOUN
gs-3921	890	16	using	use	VERB
gs-3921	890	17	in	in	ADP
gs-3921	890	18	pharmaceutical	pharmaceutical	ADJ
gs-3921	890	19	services	service	NOUN
gs-3921	890	20	”	"	PUNCT
gs-3921	890	21	.	.	PUNCT
gs-3921	891	1	experimental	experimental	ADJ
gs-3921	891	2	and	and	CCONJ
gs-3921	891	3	clinical	clinical	ADJ
gs-3921	891	4	medicine	medicine	NOUN
gs-3921	891	5	georgia	georgia	PROPN
gs-3921	891	6	,	,	PUNCT
gs-3921	891	7	no	no	INTJ
gs-3921	891	8	.	.	NOUN
gs-3921	891	9	4	4	NUM
gs-3921	891	10	(	(	PUNCT
gs-3921	891	11	september):122	september):122	PROPN
gs-3921	891	12	-	-	PUNCT
gs-3921	891	13	25	25	NUM
gs-3921	891	14	.	.	PUNCT
gs-3921	892	1	https://doi.org/10.52340/jecm.2024.04.33	https://doi.org/10.52340/jecm.2024.04.33	PROPN
gs-3921	892	2	.	.	PROPN
gs-3921	892	3	49	49	NUM
gs-3921	892	4	.	.	PUNCT
gs-3921	893	1	sulashvili	sulashvili	PROPN
gs-3921	893	2	n	n	CCONJ
gs-3921	893	3	,	,	PUNCT
gs-3921	893	4	davitashvili	davitashvili	PROPN
gs-3921	893	5	m	m	PROPN
gs-3921	893	6	,	,	PUNCT
gs-3921	893	7	gorgaslidze	gorgaslidze	ADJ
gs-3921	893	8	n	n	CCONJ
gs-3921	893	9	,	,	PUNCT
gs-3921	893	10	gabunia	gabunia	NOUN
gs-3921	893	11	l	l	NOUN
gs-3921	893	12	,	,	PUNCT
gs-3921	893	13	beglaryan	beglaryan	PROPN
gs-3921	893	14	m	m	PROPN
gs-3921	893	15	,	,	PUNCT
gs-3921	893	16	alavidze	alavidze	PROPN
gs-3921	893	17	n	n	CCONJ
gs-3921	893	18	,	,	PUNCT
gs-3921	893	19	et	et	PROPN
gs-3921	893	20	al	al	PROPN
gs-3921	893	21	.	.	PUNCT
gs-3921	894	1	the	the	DET
gs-3921	894	2	scientific	scientific	ADJ
gs-3921	894	3	discussion	discussion	NOUN
gs-3921	894	4	of	of	ADP
gs-3921	894	5	some	some	DET
gs-3921	894	6	issues	issue	NOUN
gs-3921	894	7	of	of	ADP
gs-3921	894	8	features	feature	NOUN
gs-3921	894	9	and	and	CCONJ
gs-3921	894	10	challenges	challenge	NOUN
gs-3921	894	11	of	of	ADP
gs-3921	894	12	using	use	VERB
gs-3921	894	13	of	of	ADP
gs-3921	894	14	car	car	NOUN
gs-3921	894	15	-	-	PUNCT
gs-3921	894	16	t	t	NOUN
gs-3921	894	17	cells	cell	NOUN
gs-3921	894	18	in	in	ADP
gs-3921	894	19	immunotherapy	immunotherapy	NOUN
gs-3921	894	20	.	.	PUNCT
gs-3921	895	1	gs	gs	X
gs-3921	896	1	[	[	X
gs-3921	896	2	internet	internet	NOUN
gs-3921	896	3	]	]	PUNCT
gs-3921	896	4	.	.	PUNCT
gs-3921	897	1	2024	2024	NUM
gs-3921	897	2	nov	nov	PROPN
gs-3921	897	3	.	.	PROPN
gs-3921	897	4	26	26	NUM
gs-3921	897	5	[	[	X
gs-3921	897	6	cited	cite	VERB
gs-3921	897	7	2025	2025	NUM
gs-3921	897	8	jul	jul	PROPN
gs-3921	897	9	.	.	PUNCT
gs-3921	897	10	12];6(4):263	12];6(4):263	NUM
gs-3921	897	11	-	-	SYM
gs-3921	897	12	90	90	NUM
gs-3921	897	13	.	.	PUNCT
gs-3921	898	1	available	available	ADJ
gs-3921	898	2	from	from	ADP
gs-3921	898	3	:	:	PUNCT
gs-3921	898	4	https://journals.4science.ge/index.php/gs/article/view/3214	https://journals.4science.ge/index.php/gs/article/view/3214	X
gs-3921	898	5	.	.	PUNCT
gs-3921	899	1	50	50	NUM
gs-3921	899	2	.	.	X
gs-3921	899	3	sulashvili	sulashvili	NOUN
gs-3921	899	4	,	,	PUNCT
gs-3921	899	5	nodar	nodar	INTJ
gs-3921	899	6	,	,	PUNCT
gs-3921	899	7	udgam	udgam	NOUN
gs-3921	899	8	yaduvanshi	yaduvanshi	PROPN
gs-3921	899	9	,	,	PUNCT
gs-3921	899	10	mohini	mohini	PROPN
gs-3921	899	11	yadav	yadav	PROPN
gs-3921	899	12	,	,	PUNCT
gs-3921	899	13	luiza	luiza	PROPN
gs-3921	899	14	gabunia	gabunia	PROPN
gs-3921	899	15	,	,	PUNCT
gs-3921	899	16	ketevan	ketevan	PROPN
gs-3921	899	17	ghambashidze	ghambashidze	PROPN
gs-3921	899	18	,	,	PUNCT
gs-3921	899	19	nana	nana	PROPN
gs-3921	899	20	gorgaslidze	gorgaslidze	PROPN
gs-3921	899	21	,	,	PUNCT
gs-3921	899	22	margarita	margarita	PROPN
gs-3921	899	23	beglaryan	beglaryan	PROPN
gs-3921	899	24	,	,	PUNCT
gs-3921	899	25	et	et	PROPN
gs-3921	899	26	al	al	PROPN
gs-3921	899	27	.	.	PROPN
gs-3921	899	28	2025	2025	NUM
gs-3921	899	29	.	.	PUNCT
gs-3921	900	1	“	"	PUNCT
gs-3921	900	2	the	the	DET
gs-3921	900	3	scientific	scientific	ADJ
gs-3921	900	4	discourse	discourse	NOUN
gs-3921	900	5	of	of	ADP
gs-3921	900	6	features	feature	NOUN
gs-3921	900	7	of	of	ADP
gs-3921	900	8	clinical	clinical	ADJ
gs-3921	900	9	use	use	NOUN
gs-3921	900	10	and	and	CCONJ
gs-3921	900	11	pharmacology	pharmacology	NOUN
gs-3921	900	12	of	of	ADP
gs-3921	900	13	vasoconstrictors	vasoconstrictor	NOUN
gs-3921	900	14	and	and	CCONJ
gs-3921	900	15	their	their	PRON
gs-3921	900	16	impact	impact	NOUN
gs-3921	900	17	on	on	ADP
gs-3921	900	18	cardiac	cardiac	ADJ
gs-3921	900	19	function	function	NOUN
gs-3921	900	20	”	"	PUNCT
gs-3921	900	21	.	.	PUNCT
gs-3921	901	1	junior	junior	ADJ
gs-3921	901	2	researchers	researcher	NOUN
gs-3921	901	3	3	3	NUM
gs-3921	901	4	(	(	PUNCT
gs-3921	901	5	1):28	1):28	NUM
gs-3921	901	6	-	-	SYM
gs-3921	901	7	68	68	NUM
gs-3921	901	8	.	.	PUNCT
gs-3921	902	1	https://doi.org/10.52340/jr.2025.03.01.02	https://doi.org/10.52340/jr.2025.03.01.02	X
gs-3921	902	2	.	.	NOUN
gs-3921	902	3	51	51	NUM
gs-3921	902	4	.	.	PUNCT
gs-3921	903	1	sulashvili	sulashvili	PROPN
gs-3921	903	2	n	n	CCONJ
gs-3921	903	3	,	,	PUNCT
gs-3921	903	4	nimangre	nimangre	PROPN
gs-3921	903	5	rr	rr	PROPN
gs-3921	903	6	.	.	PUNCT
gs-3921	904	1	manifestation	manifestation	NOUN
gs-3921	904	2	of	of	ADP
gs-3921	904	3	some	some	DET
gs-3921	904	4	aspects	aspect	NOUN
gs-3921	904	5	of	of	ADP
gs-3921	904	6	cardiovascular	cardiovascular	ADJ
gs-3921	904	7	diseases	disease	NOUN
gs-3921	904	8	,	,	PUNCT
gs-3921	904	9	implications	implication	NOUN
gs-3921	904	10	,	,	PUNCT
gs-3921	904	11	pharmacotherapeutic	pharmacotherapeutic	ADJ
gs-3921	904	12	strategies	strategy	NOUN
gs-3921	904	13	,	,	PUNCT
gs-3921	904	14	effects	effect	NOUN
gs-3921	904	15	,	,	PUNCT
gs-3921	904	16	impacts	impact	NOUN
gs-3921	904	17	and	and	CCONJ
gs-3921	904	18	potential	potential	ADJ
gs-3921	904	19	hazards	hazard	NOUN
gs-3921	904	20	in	in	ADP
gs-3921	904	21	general	general	ADJ
gs-3921	904	22	.	.	PUNCT
gs-3921	905	1	jr	jr	PROPN
gs-3921	906	1	[	[	X
gs-3921	906	2	internet	internet	NOUN
gs-3921	906	3	]	]	PUNCT
gs-3921	906	4	.	.	PUNCT
gs-3921	907	1	2025	2025	NUM
gs-3921	907	2	feb	feb	X
gs-3921	907	3	.	.	PROPN
gs-3921	907	4	7	7	NUM
gs-3921	907	5	[	[	X
gs-3921	907	6	cited	cite	VERB
gs-3921	907	7	2025	2025	NUM
gs-3921	907	8	jul	jul	PROPN
gs-3921	907	9	.	.	PUNCT
gs-3921	908	1	12];3(1):1	12];3(1):1	NUM
gs-3921	908	2	-	-	SYM
gs-3921	908	3	27	27	NUM
gs-3921	908	4	.	.	PUNCT
gs-3921	909	1	available	available	ADJ
gs-3921	909	2	from	from	ADP
gs-3921	909	3	:	:	PUNCT
gs-3921	909	4	https://journals.4science.ge/index.php/jr/article/view/3393	https://journals.4science.ge/index.php/jr/article/view/3393	PROPN
gs-3921	909	5	.	.	PUNCT
gs-3921	910	1	52	52	NUM
gs-3921	910	2	.	.	PUNCT
gs-3921	911	1	gorgaslidze	gorgaslidze	PROPN
gs-3921	911	2	,	,	PUNCT
gs-3921	911	3	nana	nana	PROPN
gs-3921	911	4	,	,	PUNCT
gs-3921	911	5	nodar	nodar	NOUN
gs-3921	911	6	sulashvili	sulashvili	NOUN
gs-3921	911	7	,	,	PUNCT
gs-3921	911	8	luiza	luiza	PROPN
gs-3921	911	9	gabunia	gabunia	PROPN
gs-3921	911	10	,	,	PUNCT
gs-3921	911	11	shafiga	shafiga	PROPN
gs-3921	911	12	topchiyeva	topchiyeva	PROPN
gs-3921	911	13	,	,	PUNCT
gs-3921	911	14	vira	vira	PROPN
gs-3921	911	15	kravchenko	kravchenko	PROPN
gs-3921	911	16	,	,	PUNCT
gs-3921	911	17	marina	marina	PROPN
gs-3921	911	18	giorgobiani	giorgobiani	PROPN
gs-3921	911	19	,	,	PUNCT
gs-3921	911	20	irina	irina	PROPN
gs-3921	911	21	zarnadze	zarnadze	PROPN
gs-3921	911	22	,	,	PUNCT
gs-3921	911	23	and	and	CCONJ
gs-3921	911	24	igor	igor	NOUN
gs-3921	911	25	seniuk	seniuk	NOUN
gs-3921	911	26	.	.	PUNCT
gs-3921	912	1	2024	2024	NUM
gs-3921	912	2	.	.	PUNCT
gs-3921	913	1	“	"	PUNCT
gs-3921	913	2	manifestation	manifestation	NOUN
gs-3921	913	3	of	of	ADP
gs-3921	913	4	some	some	DET
gs-3921	913	5	key	key	ADJ
gs-3921	913	6	issue	issue	NOUN
gs-3921	913	7	aspects	aspect	NOUN
gs-3921	913	8	of	of	ADP
gs-3921	913	9	features	feature	NOUN
gs-3921	913	10	of	of	ADP
gs-3921	913	11	medicines	medicine	NOUN
gs-3921	913	12	turnover	turnover	NOUN
gs-3921	913	13	and	and	CCONJ
gs-3921	913	14	its	its	PRON
gs-3921	913	15	influence	influence	NOUN
gs-3921	913	16	on	on	ADP
gs-3921	913	17	environment	environment	NOUN
gs-3921	913	18	and	and	CCONJ
gs-3921	913	19	medical	medical	ADJ
gs-3921	913	20	-	-	PUNCT
gs-3921	913	21	ecological	ecological	ADJ
gs-3921	913	22	safety	safety	NOUN
gs-3921	913	23	challenges	challenge	NOUN
gs-3921	913	24	globally	globally	ADV
gs-3921	913	25	”	"	PUNCT
gs-3921	913	26	.	.	PUNCT
gs-3921	914	1	experimental	experimental	ADJ
gs-3921	914	2	and	and	CCONJ
gs-3921	914	3	clinical	clinical	ADJ
gs-3921	914	4	medicine	medicine	NOUN
gs-3921	914	5	georgia	georgia	PROPN
gs-3921	914	6	,	,	PUNCT
gs-3921	914	7	no	no	INTJ
gs-3921	914	8	.	.	NOUN
gs-3921	914	9	4	4	NUM
gs-3921	914	10	(	(	PUNCT
gs-3921	914	11	september):130	september):130	PROPN
gs-3921	914	12	-	-	PUNCT
gs-3921	914	13	32	32	NUM
gs-3921	914	14	.	.	PUNCT
gs-3921	915	1	https://doi.org/10.52340/jecm.2024.04.35	https://doi.org/10.52340/jecm.2024.04.35	PROPN
gs-3921	915	2	.	.	PUNCT
gs-3921	916	1	53	53	NUM
gs-3921	916	2	.	.	PUNCT
gs-3921	916	3	sulashvili	sulashvili	NOUN
gs-3921	916	4	,	,	PUNCT
gs-3921	916	5	nodar	nodar	ADV
gs-3921	916	6	,	,	PUNCT
gs-3921	916	7	margarita	margarita	PROPN
gs-3921	916	8	beglaryan	beglaryan	PROPN
gs-3921	916	9	,	,	PUNCT
gs-3921	916	10	nana	nana	PROPN
gs-3921	916	11	gorgaslidze	gorgaslidze	PROPN
gs-3921	916	12	,	,	PUNCT
gs-3921	916	13	seyran	seyran	PROPN
gs-3921	916	14	kocharyan	kocharyan	PROPN
gs-3921	916	15	,	,	PUNCT
gs-3921	916	16	naira	naira	PROPN
gs-3921	916	17	chichoyan	chichoyan	PROPN
gs-3921	916	18	,	,	PUNCT
gs-3921	916	19	luiza	luiza	PROPN
gs-3921	916	20	gabunia	gabunia	PROPN
gs-3921	916	21	,	,	PUNCT
gs-3921	916	22	natia	natia	PROPN
gs-3921	916	23	kvizhinadze	kvizhinadze	PROPN
gs-3921	916	24	,	,	PUNCT
gs-3921	916	25	et	et	PROPN
gs-3921	916	26	al	al	PROPN
gs-3921	916	27	.	.	PROPN
gs-3921	916	28	2024	2024	NUM
gs-3921	916	29	.	.	PUNCT
gs-3921	917	1	“	"	PUNCT
gs-3921	917	2	the	the	DET
gs-3921	917	3	scientific	scientific	ADJ
gs-3921	917	4	discussion	discussion	NOUN
gs-3921	917	5	of	of	ADP
gs-3921	917	6	some	some	DET
gs-3921	917	7	key	key	ADJ
gs-3921	917	8	issue	issue	NOUN
gs-3921	917	9	aspects	aspect	NOUN
gs-3921	917	10	of	of	ADP
gs-3921	917	11	pharmacists	pharmacist	NOUN
gs-3921	917	12	’	’	PART
gs-3921	917	13	vocational	vocational	ADJ
gs-3921	917	14	challenges	challenge	NOUN
gs-3921	917	15	,	,	PUNCT
gs-3921	917	16	vision	vision	NOUN
gs-3921	917	17	,	,	PUNCT
gs-3921	917	18	opportunities	opportunity	NOUN
gs-3921	917	19	,	,	PUNCT
gs-3921	917	20	outlooks	outlook	NOUN
gs-3921	917	21	,	,	PUNCT
gs-3921	917	22	objections	objection	NOUN
gs-3921	917	23	,	,	PUNCT
gs-3921	917	24	appearances	appearance	NOUN
gs-3921	917	25	and	and	CCONJ
gs-3921	917	26	indentation	indentation	NOUN
gs-3921	917	27	in	in	ADP
gs-3921	917	28	general	general	ADJ
gs-3921	917	29	and	and	CCONJ
gs-3921	917	30	public	public	ADJ
gs-3921	917	31	health	health	NOUN
gs-3921	917	32	care	care	NOUN
gs-3921	917	33	direction	direction	NOUN
gs-3921	917	34	”	"	PUNCT
gs-3921	917	35	.	.	PUNCT
gs-3921	918	1	experimental	experimental	ADJ
gs-3921	918	2	and	and	CCONJ
gs-3921	918	3	clinical	clinical	ADJ
gs-3921	918	4	medicine	medicine	NOUN
gs-3921	918	5	georgia	georgia	PROPN
gs-3921	918	6	,	,	PUNCT
gs-3921	918	7	no	no	INTJ
gs-3921	918	8	.	.	NOUN
gs-3921	918	9	4	4	NUM
gs-3921	918	10	(	(	PUNCT
gs-3921	918	11	september):126	september):126	PROPN
gs-3921	918	12	-	-	PUNCT
gs-3921	918	13	29	29	NUM
gs-3921	918	14	.	.	PUNCT
gs-3921	919	1	https://doi.org/10.52340/jecm.2024.04.34	https://doi.org/10.52340/jecm.2024.04.34	NOUN
gs-3921	919	2	.	.	PUNCT
gs-3921	920	1	georgian	georgian	ADJ
gs-3921	920	2	scientists/ქართველი	scientists/ქართველი	PROPN
gs-3921	920	3	მეცნიერები	მეცნიერები	NOUN
gs-3921	920	4	ტ.	ტ.	VERB
gs-3921	920	5	7	7	NUM
gs-3921	920	6	n	n	DET
gs-3921	920	7	3	3	NUM
gs-3921	920	8	,	,	PUNCT
gs-3921	920	9	2025	2025	NUM
gs-3921	920	10	262	262	NUM
gs-3921	920	11	54	54	NUM
gs-3921	920	12	.	.	PUNCT
gs-3921	921	1	aphkhazava	aphkhazava	PROPN
gs-3921	921	2	,	,	PUNCT
gs-3921	921	3	david	david	PROPN
gs-3921	921	4	,	,	PUNCT
gs-3921	921	5	nodar	nodar	PROPN
gs-3921	921	6	sulashvili	sulashvili	NOUN
gs-3921	921	7	,	,	PUNCT
gs-3921	921	8	tamar	tamar	PROPN
gs-3921	921	9	tupinashvili	tupinashvili	NOUN
gs-3921	921	10	,	,	PUNCT
gs-3921	921	11	and	and	CCONJ
gs-3921	921	12	maia	maia	PROPN
gs-3921	921	13	nozadze	nozadze	PROPN
gs-3921	921	14	.	.	PUNCT
gs-3921	922	1	2024	2024	NUM
gs-3921	922	2	.	.	PUNCT
gs-3921	923	1	“	"	PUNCT
gs-3921	923	2	dynamic	dynamic	ADJ
gs-3921	923	3	cellular	cellular	ADJ
gs-3921	923	4	equilibrium	equilibrium	NOUN
gs-3921	923	5	theory	theory	NOUN
gs-3921	923	6	of	of	ADP
gs-3921	923	7	aging	aging	NOUN
gs-3921	923	8	:	:	PUNCT
gs-3921	923	9	integrating	integrate	VERB
gs-3921	923	10	maintenance	maintenance	NOUN
gs-3921	923	11	and	and	CCONJ
gs-3921	923	12	accumulation	accumulation	NOUN
gs-3921	923	13	in	in	ADP
gs-3921	923	14	the	the	DET
gs-3921	923	15	aging	age	VERB
gs-3921	923	16	process	process	NOUN
gs-3921	923	17	”	"	PUNCT
gs-3921	923	18	.	.	PUNCT
gs-3921	924	1	scientific	scientific	ADJ
gs-3921	924	2	journal	journal	NOUN
gs-3921	924	3	„	„	PUNCT
gs-3921	924	4	spectri	spectri	ADJ
gs-3921	924	5	“	"	PUNCT
gs-3921	924	6	8	8	NUM
gs-3921	924	7	(	(	PUNCT
gs-3921	924	8	2	2	NUM
gs-3921	924	9	)	)	PUNCT
gs-3921	924	10	.	.	PUNCT
gs-3921	925	1	https://doi.org/10.52340/spectri.2023.08.02.03	https://doi.org/10.52340/spectri.2023.08.02.03	X
gs-3921	925	2	.	.	X
gs-3921	926	1	55	55	NUM
gs-3921	926	2	.	.	PUNCT
gs-3921	927	1	luzum	luzum	PROPN
gs-3921	927	2	,	,	PUNCT
gs-3921	927	3	jennifer	jennifer	PROPN
gs-3921	927	4	a.	a.	PROPN
gs-3921	927	5	,	,	PUNCT
gs-3921	927	6	kristine	kristine	PROPN
gs-3921	927	7	r.	r.	PROPN
gs-3921	927	8	hoffman	hoffman	PROPN
gs-3921	927	9	,	,	PUNCT
gs-3921	927	10	and	and	CCONJ
gs-3921	927	11	mary	mary	PROPN
gs-3921	927	12	v.	v.	ADP
gs-3921	927	13	relling	relling	NOUN
gs-3921	927	14	.	.	PUNCT
gs-3921	928	1	2017	2017	NUM
gs-3921	928	2	.	.	PUNCT
gs-3921	929	1	“	"	PUNCT
gs-3921	929	2	the	the	DET
gs-3921	929	3	pharmacogenomics	pharmacogenomics	PROPN
gs-3921	929	4	research	research	PROPN
gs-3921	929	5	network	network	NOUN
gs-3921	929	6	translational	translational	ADJ
gs-3921	929	7	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	929	8	program	program	NOUN
gs-3921	929	9	:	:	PUNCT
gs-3921	929	10	outcomes	outcome	NOUN
gs-3921	929	11	and	and	CCONJ
gs-3921	929	12	metrics	metric	NOUN
gs-3921	929	13	of	of	ADP
gs-3921	929	14	pharmacogenetic	pharmacogenetic	ADJ
gs-3921	929	15	implementation	implementation	NOUN
gs-3921	929	16	across	across	ADP
gs-3921	929	17	diverse	diverse	ADJ
gs-3921	929	18	healthcare	healthcare	NOUN
gs-3921	929	19	systems	system	NOUN
gs-3921	929	20	.	.	PUNCT
gs-3921	929	21	”	"	PUNCT
gs-3921	930	1	clinical	clinical	ADJ
gs-3921	930	2	pharmacology	pharmacology	NOUN
gs-3921	930	3	&	&	CCONJ
gs-3921	930	4	therapeutics	therapeutic	NOUN
gs-3921	930	5	102	102	NUM
gs-3921	930	6	(	(	PUNCT
gs-3921	930	7	3	3	NUM
gs-3921	930	8	):	):	PUNCT
gs-3921	930	9	502–10	502–10	NUM
gs-3921	930	10	.	.	PUNCT
gs-3921	931	1	56	56	NUM
gs-3921	931	2	.	.	PUNCT
gs-3921	932	1	martin	martin	PROPN
gs-3921	932	2	,	,	PUNCT
gs-3921	932	3	maria	maria	PROPN
gs-3921	932	4	a.	a.	PROPN
gs-3921	932	5	,	,	PUNCT
gs-3921	932	6	j.	j.	PROPN
gs-3921	932	7	kevin	kevin	PROPN
gs-3921	932	8	hicks	hicks	PROPN
gs-3921	932	9	,	,	PUNCT
gs-3921	932	10	and	and	CCONJ
gs-3921	932	11	james	james	PROPN
gs-3921	932	12	m.	m.	PROPN
gs-3921	932	13	huddart	huddart	PROPN
gs-3921	932	14	.	.	PUNCT
gs-3921	933	1	2014	2014	NUM
gs-3921	933	2	.	.	PUNCT
gs-3921	934	1	“	"	PUNCT
gs-3921	934	2	clinical	clinical	ADJ
gs-3921	934	3	implementation	implementation	NOUN
gs-3921	934	4	of	of	ADP
gs-3921	934	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	934	6	:	:	PUNCT
gs-3921	934	7	overcoming	overcome	VERB
gs-3921	934	8	genetic	genetic	ADJ
gs-3921	934	9	exceptionalism	exceptionalism	NOUN
gs-3921	934	10	.	.	PUNCT
gs-3921	934	11	”	"	PUNCT
gs-3921	935	1	the	the	DET
gs-3921	935	2	lancet	lancet	PROPN
gs-3921	935	3	respiratory	respiratory	ADJ
gs-3921	935	4	medicine	medicine	NOUN
gs-3921	935	5	2	2	NUM
gs-3921	935	6	(	(	PUNCT
gs-3921	935	7	7	7	NUM
gs-3921	935	8	):	):	PUNCT
gs-3921	935	9	587–89	587–89	NUM
gs-3921	935	10	.	.	PUNCT
gs-3921	935	11	57	57	NUM
gs-3921	935	12	.	.	X
gs-3921	936	1	mega	mega	PROPN
gs-3921	936	2	,	,	PUNCT
gs-3921	936	3	jessica	jessica	PROPN
gs-3921	936	4	l.	l.	PROPN
gs-3921	936	5	,	,	PUNCT
gs-3921	936	6	and	and	CCONJ
gs-3921	936	7	calum	calum	PROPN
gs-3921	936	8	a.	a.	PROPN
gs-3921	936	9	macrae	macrae	PROPN
gs-3921	936	10	.	.	PUNCT
gs-3921	936	11	2015	2015	NUM
gs-3921	936	12	.	.	PUNCT
gs-3921	937	1	“	"	PUNCT
gs-3921	937	2	defining	define	VERB
gs-3921	937	3	the	the	DET
gs-3921	937	4	role	role	NOUN
gs-3921	937	5	of	of	ADP
gs-3921	937	6	genetics	genetic	NOUN
gs-3921	937	7	in	in	ADP
gs-3921	937	8	clinical	clinical	ADJ
gs-3921	937	9	drug	drug	NOUN
gs-3921	937	10	development	development	NOUN
gs-3921	937	11	.	.	PUNCT
gs-3921	937	12	”	"	PUNCT
gs-3921	938	1	nature	nature	NOUN
gs-3921	938	2	reviews	review	VERB
gs-3921	938	3	drug	drug	NOUN
gs-3921	938	4	discovery	discovery	NOUN
gs-3921	938	5	14	14	NUM
gs-3921	938	6	(	(	PUNCT
gs-3921	938	7	8)	8)	NUM
gs-3921	938	8	:	:	PUNCT
gs-3921	938	9	573–86	573–86	NUM
gs-3921	938	10	.	.	PUNCT
gs-3921	939	1	58	58	NUM
gs-3921	939	2	.	.	PUNCT
gs-3921	940	1	gurwitz	gurwitz	PROPN
gs-3921	940	2	,	,	PUNCT
gs-3921	940	3	david	david	PROPN
gs-3921	940	4	,	,	PUNCT
gs-3921	940	5	and	and	CCONJ
gs-3921	940	6	vardit	vardit	NOUN
gs-3921	940	7	ravitsky	ravitsky	NOUN
gs-3921	940	8	.	.	PUNCT
gs-3921	941	1	2020	2020	NUM
gs-3921	941	2	.	.	PUNCT
gs-3921	942	1	“	"	PUNCT
gs-3921	942	2	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	942	3	in	in	ADP
gs-3921	942	4	the	the	DET
gs-3921	942	5	age	age	NOUN
gs-3921	942	6	of	of	ADP
gs-3921	942	7	big	big	ADJ
gs-3921	942	8	data	datum	NOUN
gs-3921	942	9	.	.	PUNCT
gs-3921	942	10	”	"	PUNCT
gs-3921	943	1	nature	nature	NOUN
gs-3921	943	2	reviews	review	VERB
gs-3921	943	3	genetics	genetics	NOUN
gs-3921	943	4	21	21	NUM
gs-3921	943	5	(	(	PUNCT
gs-3921	943	6	3	3	NUM
gs-3921	943	7	):	):	PUNCT
gs-3921	943	8	148–49	148–49	NUM
gs-3921	943	9	.	.	PUNCT
gs-3921	944	1	59	59	NUM
gs-3921	944	2	.	.	PUNCT
gs-3921	945	1	suarez	suarez	PROPN
gs-3921	945	2	-	-	PUNCT
gs-3921	945	3	kurtz	kurtz	PROPN
gs-3921	945	4	,	,	PUNCT
gs-3921	945	5	guilherme	guilherme	PROPN
gs-3921	945	6	,	,	PUNCT
gs-3921	945	7	and	and	CCONJ
gs-3921	945	8	flavia	flavia	PROPN
gs-3921	945	9	m.	m.	PROPN
gs-3921	945	10	motta	motta	PROPN
gs-3921	945	11	.	.	PROPN
gs-3921	945	12	2019	2019	NUM
gs-3921	945	13	.	.	PUNCT
gs-3921	946	1	“	"	PUNCT
gs-3921	946	2	population	population	NOUN
gs-3921	946	3	diversity	diversity	NOUN
gs-3921	946	4	in	in	ADP
gs-3921	946	5	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	946	6	:	:	PUNCT
gs-3921	946	7	implications	implication	NOUN
gs-3921	946	8	for	for	ADP
gs-3921	946	9	drug	drug	NOUN
gs-3921	946	10	development	development	NOUN
gs-3921	946	11	and	and	CCONJ
gs-3921	946	12	clinical	clinical	ADJ
gs-3921	946	13	practice	practice	NOUN
gs-3921	946	14	.	.	PUNCT
gs-3921	946	15	”	"	PUNCT
gs-3921	947	1	british	british	ADJ
gs-3921	947	2	journal	journal	PROPN
gs-3921	947	3	of	of	ADP
gs-3921	947	4	clinical	clinical	ADJ
gs-3921	947	5	pharmacology	pharmacology	NOUN
gs-3921	947	6	85	85	NUM
gs-3921	947	7	(	(	PUNCT
gs-3921	947	8	12	12	NUM
gs-3921	947	9	):	):	PUNCT
gs-3921	947	10	2648–53	2648–53	NUM
gs-3921	947	11	.	.	PUNCT
gs-3921	948	1	60	60	NUM
gs-3921	948	2	.	.	PUNCT
gs-3921	949	1	johnson	johnson	PROPN
gs-3921	949	2	,	,	PUNCT
gs-3921	949	3	julie	julie	PROPN
gs-3921	949	4	a.	a.	PROPN
gs-3921	949	5	,	,	PUNCT
gs-3921	949	6	and	and	CCONJ
gs-3921	949	7	kristin	kristin	PROPN
gs-3921	949	8	w.	w.	PROPN
gs-3921	949	9	weitzel	weitzel	PROPN
gs-3921	949	10	.	.	PUNCT
gs-3921	949	11	2016	2016	NUM
gs-3921	949	12	.	.	PUNCT
gs-3921	950	1	“	"	PUNCT
gs-3921	950	2	advancing	advance	VERB
gs-3921	950	3	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	950	4	as	as	ADP
gs-3921	950	5	a	a	DET
gs-3921	950	6	component	component	NOUN
gs-3921	950	7	of	of	ADP
gs-3921	950	8	precision	precision	NOUN
gs-3921	950	9	medicine	medicine	NOUN
gs-3921	950	10	:	:	PUNCT
gs-3921	950	11	how	how	SCONJ
gs-3921	950	12	,	,	PUNCT
gs-3921	950	13	where	where	SCONJ
gs-3921	950	14	,	,	PUNCT
gs-3921	950	15	and	and	CCONJ
gs-3921	950	16	who	who	PRON
gs-3921	950	17	?	?	PUNCT
gs-3921	950	18	”	"	PUNCT
gs-3921	950	19	clinical	clinical	ADJ
gs-3921	950	20	pharmacology	pharmacology	NOUN
gs-3921	950	21	&	&	CCONJ
gs-3921	950	22	therapeutics	therapeutic	NOUN
gs-3921	950	23	99	99	NUM
gs-3921	950	24	(	(	PUNCT
gs-3921	950	25	2	2	NUM
gs-3921	950	26	):	):	PUNCT
gs-3921	950	27	154–56	154–56	NUM
gs-3921	950	28	.	.	PUNCT
gs-3921	951	1	61	61	NUM
gs-3921	951	2	.	.	X
gs-3921	951	3	o'donnell	o'donnell	PROPN
gs-3921	951	4	,	,	PUNCT
gs-3921	951	5	paul	paul	PROPN
gs-3921	951	6	h.	h.	PROPN
gs-3921	951	7	,	,	PUNCT
gs-3921	951	8	mark	mark	PROPN
gs-3921	951	9	j.	j.	PROPN
gs-3921	951	10	ratain	ratain	PROPN
gs-3921	951	11	,	,	PUNCT
gs-3921	951	12	and	and	CCONJ
gs-3921	951	13	m.	m.	PROPN
gs-3921	951	14	eileen	eileen	PROPN
gs-3921	951	15	dolan	dolan	PROPN
gs-3921	951	16	.	.	PUNCT
gs-3921	951	17	2012	2012	NUM
gs-3921	951	18	.	.	PUNCT
gs-3921	952	1	“	"	PUNCT
gs-3921	952	2	phase	phase	NOUN
gs-3921	952	3	ii	ii	NOUN
gs-3921	952	4	clinical	clinical	ADJ
gs-3921	952	5	trials	trial	NOUN
gs-3921	952	6	of	of	ADP
gs-3921	952	7	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	952	8	in	in	ADP
gs-3921	952	9	oncology	oncology	NOUN
gs-3921	952	10	.	.	PUNCT
gs-3921	952	11	”	"	PUNCT
gs-3921	953	1	clinical	clinical	ADJ
gs-3921	953	2	cancer	cancer	NOUN
gs-3921	953	3	research	research	NOUN
gs-3921	953	4	18	18	NUM
gs-3921	953	5	(	(	PUNCT
gs-3921	953	6	13	13	NUM
gs-3921	953	7	):	):	PUNCT
gs-3921	953	8	3461–66	3461–66	NOUN
gs-3921	953	9	.	.	PUNCT
gs-3921	953	10	62	62	NUM
gs-3921	953	11	.	.	PUNCT
gs-3921	954	1	beitelshees	beitelshees	PROPN
gs-3921	954	2	,	,	PUNCT
gs-3921	954	3	amber	amber	PROPN
gs-3921	954	4	l.	l.	PROPN
gs-3921	954	5	,	,	PUNCT
gs-3921	954	6	james	james	PROPN
gs-3921	954	7	m.	m.	PROPN
gs-3921	954	8	huddart	huddart	PROPN
gs-3921	954	9	,	,	PUNCT
gs-3921	954	10	and	and	CCONJ
gs-3921	954	11	marylyn	marylyn	PROPN
gs-3921	954	12	d.	d.	PROPN
gs-3921	954	13	ritchie	ritchie	PROPN
gs-3921	954	14	.	.	PROPN
gs-3921	954	15	2020	2020	NUM
gs-3921	954	16	.	.	PUNCT
gs-3921	955	1	“	"	PUNCT
gs-3921	955	2	precision	precision	NOUN
gs-3921	955	3	medicine	medicine	NOUN
gs-3921	955	4	and	and	CCONJ
gs-3921	955	5	pharmacogenetics	pharmacogenetic	NOUN
gs-3921	955	6	:	:	PUNCT
gs-3921	955	7	what	what	PRON
gs-3921	955	8	does	do	AUX
gs-3921	955	9	the	the	DET
gs-3921	955	10	future	future	ADJ
gs-3921	955	11	hold	hold	VERB
gs-3921	955	12	?	?	PUNCT
gs-3921	955	13	”	"	PUNCT
gs-3921	955	14	current	current	ADJ
gs-3921	955	15	genetic	genetic	ADJ
gs-3921	955	16	medicine	medicine	NOUN
gs-3921	955	17	reports	report	VERB
gs-3921	955	18	8	8	NUM
gs-3921	955	19	(	(	PUNCT
gs-3921	955	20	1	1	NUM
gs-3921	955	21	):	):	PUNCT
gs-3921	955	22	1–9	1–9	NUM
gs-3921	955	23	.	.	PROPN
gs-3921	955	24	63	63	NUM
gs-3921	955	25	.	.	PUNCT
gs-3921	956	1	mcgraw	mcgraw	PROPN
gs-3921	956	2	,	,	PUNCT
gs-3921	956	3	jeffery	jeffery	PROPN
gs-3921	956	4	,	,	PUNCT
gs-3921	956	5	j.	j.	PROPN
gs-3921	956	6	kevin	kevin	PROPN
gs-3921	956	7	hicks	hicks	PROPN
gs-3921	956	8	,	,	PUNCT
gs-3921	956	9	and	and	CCONJ
gs-3921	956	10	teri	teri	PROPN
gs-3921	956	11	e.	e.	PROPN
gs-3921	956	12	klein	klein	PROPN
gs-3921	956	13	.	.	PROPN
gs-3921	957	1	2013	2013	NUM
gs-3921	957	2	.	.	PUNCT
gs-3921	958	1	“	"	PUNCT
gs-3921	958	2	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	958	3	:	:	PUNCT
gs-3921	958	4	an	an	DET
gs-3921	958	5	introduction	introduction	NOUN
gs-3921	958	6	and	and	CCONJ
gs-3921	958	7	clinical	clinical	ADJ
gs-3921	958	8	perspective	perspective	NOUN
gs-3921	958	9	.	.	PUNCT
gs-3921	958	10	”	"	PUNCT
gs-3921	959	1	current	current	ADJ
gs-3921	959	2	opinion	opinion	NOUN
gs-3921	959	3	in	in	ADP
gs-3921	959	4	cardiology	cardiology	NOUN
gs-3921	959	5	28	28	NUM
gs-3921	959	6	(	(	PUNCT
gs-3921	959	7	3	3	NUM
gs-3921	959	8	):	):	PUNCT
gs-3921	959	9	329–35	329–35	NUM
gs-3921	959	10	.	.	PUNCT
gs-3921	960	1	64	64	NUM
gs-3921	960	2	.	.	PUNCT
gs-3921	960	3	frueh	frueh	PROPN
gs-3921	960	4	,	,	PUNCT
gs-3921	960	5	felix	felix	PROPN
gs-3921	960	6	w.	w.	PROPN
gs-3921	960	7	,	,	PUNCT
gs-3921	960	8	w.	w.	PROPN
gs-3921	960	9	gregory	gregory	PROPN
gs-3921	960	10	feero	feero	PROPN
gs-3921	960	11	,	,	PUNCT
gs-3921	960	12	and	and	CCONJ
gs-3921	960	13	muin	muin	PROPN
gs-3921	960	14	j.	j.	PROPN
gs-3921	960	15	khoury	khoury	PROPN
gs-3921	960	16	.	.	PUNCT
gs-3921	960	17	2008	2008	NUM
gs-3921	960	18	.	.	PUNCT
gs-3921	961	1	“	"	PUNCT
gs-3921	961	2	the	the	DET
gs-3921	961	3	future	future	NOUN
gs-3921	961	4	of	of	ADP
gs-3921	961	5	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	961	6	:	:	PUNCT
gs-3921	961	7	integration	integration	NOUN
gs-3921	961	8	into	into	ADP
gs-3921	961	9	clinical	clinical	ADJ
gs-3921	961	10	practice	practice	NOUN
gs-3921	961	11	.	.	PUNCT
gs-3921	961	12	”	"	PUNCT
gs-3921	962	1	nature	nature	NOUN
gs-3921	962	2	reviews	review	VERB
gs-3921	962	3	genetics	genetic	NOUN
gs-3921	962	4	9	9	NUM
gs-3921	962	5	(	(	PUNCT
gs-3921	962	6	12	12	NUM
gs-3921	962	7	):	):	PUNCT
gs-3921	962	8	949–58	949–58	NUM
gs-3921	962	9	.	.	PUNCT
gs-3921	962	10	65	65	NUM
gs-3921	962	11	.	.	PUNCT
gs-3921	963	1	gurwitz	gurwitz	PROPN
gs-3921	963	2	,	,	PUNCT
gs-3921	963	3	david	david	PROPN
gs-3921	963	4	,	,	PUNCT
gs-3921	963	5	and	and	CCONJ
gs-3921	963	6	vural	vural	ADJ
gs-3921	963	7	ozdemir	ozdemir	NOUN
gs-3921	963	8	.	.	PUNCT
gs-3921	963	9	2004	2004	NUM
gs-3921	963	10	.	.	PUNCT
gs-3921	964	1	“	"	PUNCT
gs-3921	964	2	ethical	ethical	ADJ
gs-3921	964	3	issues	issue	NOUN
gs-3921	964	4	in	in	ADP
gs-3921	964	5	pharmacogenomics	pharmacogenomic	NOUN
gs-3921	964	6	research	research	NOUN
gs-3921	964	7	and	and	CCONJ
gs-3921	964	8	practice	practice	NOUN
gs-3921	964	9	.	.	PUNCT
gs-3921	964	10	”	"	PUNCT
gs-3921	965	1	pharmacogenomics	pharmacogenomics	PROPN
gs-3921	965	2	journal	journal	NOUN
gs-3921	965	3	4	4	NUM
gs-3921	965	4	(	(	PUNCT
gs-3921	965	5	2	2	NUM
gs-3921	965	6	):	):	PUNCT
gs-3921	965	7	91–96	91–96	NUM
gs-3921	965	8	.	.	PUNCT