id	sid	tid	token	lemma	pos
gs-4254	1	1	fullpdf070412025.pdf	fullpdf070412025.pdf	ADJ
gs-4254	1	2	modern	modern	ADJ
gs-4254	1	3	approaches	approach	NOUN
gs-4254	1	4	to	to	ADP
gs-4254	1	5	the	the	DET
gs-4254	1	6	pathophysiology	pathophysiology	NOUN
gs-4254	1	7	and	and	CCONJ
gs-4254	1	8	classification	classification	NOUN
gs-4254	1	9	of	of	ADP
gs-4254	1	10	shock	shock	NOUN
gs-4254	1	11	in	in	ADP
gs-4254	1	12	critical	critical	ADJ
gs-4254	1	13	care	care	NOUN
gs-4254	1	14	vakhtang	vakhtang	PROPN
gs-4254	1	15	shoshiashvili,1	shoshiashvili,1	PROPN
gs-4254	1	16	natia	natia	PROPN
gs-4254	1	17	gamkrelidze2	gamkrelidze2	PROPN
gs-4254	2	1	tbilisi	tbilisi	PROPN
gs-4254	2	2	state	state	PROPN
gs-4254	2	3	medical	medical	PROPN
gs-4254	2	4	university	university	PROPN
gs-4254	2	5	;	;	PUNCT
gs-4254	2	6	tbilisi	tbilisi	PROPN
gs-4254	2	7	,	,	PUNCT
gs-4254	2	8	georgia	georgia	PROPN
gs-4254	2	9	the	the	DET
gs-4254	2	10	word	word	NOUN
gs-4254	2	11	is	be	AUX
gs-4254	2	12	derived	derive	VERB
gs-4254	2	13	from	from	ADP
gs-4254	2	14	the	the	DET
gs-4254	2	15	french	french	ADJ
gs-4254	2	16	meaning	mean	VERB
gs-4254	2	17	a	a	DET
gs-4254	2	18	clash	clash	NOUN
gs-4254	2	19	or	or	CCONJ
gs-4254	2	20	collision	collision	VERB
gs-4254	2	21	between	between	ADP
gs-4254	2	22	two	two	NUM
gs-4254	2	23	opposing	oppose	VERB
gs-4254	2	24	forces	force	NOUN
gs-4254	2	25	.	.	PUNCT
gs-4254	3	1	historically	historically	ADV
gs-4254	3	2	,	,	PUNCT
gs-4254	3	3	numerous	numerous	ADJ
gs-4254	3	4	definitions	definition	NOUN
gs-4254	3	5	of	of	ADP
gs-4254	3	6	shock	shock	NOUN
gs-4254	3	7	have	have	AUX
gs-4254	3	8	been	be	AUX
gs-4254	3	9	proposed	propose	VERB
gs-4254	3	10	.	.	PUNCT
gs-4254	4	1	the	the	DET
gs-4254	4	2	current	current	ADJ
gs-4254	4	3	volume	volume	NOUN
gs-4254	4	4	.	.	PUNCT
gs-4254	5	1	global	global	ADJ
gs-4254	5	2	hypoperfusion	hypoperfusion	NOUN
gs-4254	5	3	leads	lead	VERB
gs-4254	5	4	to	to	ADP
gs-4254	5	5	an	an	DET
gs-4254	5	6	imbalance	imbalance	NOUN
gs-4254	5	7	between	between	ADP
gs-4254	5	8	oxygen	oxygen	NOUN
gs-4254	5	9	supply	supply	NOUN
gs-4254	5	10	and	and	CCONJ
gs-4254	5	11	demand	demand	NOUN
gs-4254	5	12	,	,	PUNCT
gs-4254	5	13	resulting	result	VERB
gs-4254	5	14	in	in	ADP
gs-4254	5	15	insufficient	insufficient	ADJ
gs-4254	5	16	atp	atp	NOUN
gs-4254	5	17	synthesis	synthesis	NOUN
gs-4254	5	18	,	,	PUNCT
gs-4254	5	19	anaerobic	anaerobic	NOUN
gs-4254	5	20	respiration	respiration	NOUN
gs-4254	5	21	,	,	PUNCT
gs-4254	5	22	and	and	CCONJ
gs-4254	5	23	lactic	lactic	ADJ
gs-4254	5	24	acidosis	acidosis	NOUN
gs-4254	5	25	.	.	PUNCT
gs-4254	6	1	therefore	therefore	ADV
gs-4254	6	2	,	,	PUNCT
gs-4254	6	3	shock	shock	NOUN
gs-4254	6	4	is	be	AUX
gs-4254	6	5	a	a	DET
gs-4254	6	6	lifethreatening	lifethreatene	VERB
gs-4254	6	7	medical	medical	ADJ
gs-4254	6	8	emergency	emergency	NOUN
gs-4254	6	9	characterized	characterize	VERB
gs-4254	6	10	by	by	ADP
gs-4254	6	11	inadequate	inadequate	ADJ
gs-4254	6	12	delivery	delivery	NOUN
gs-4254	6	13	of	of	ADP
gs-4254	6	14	oxygen	oxygen	NOUN
gs-4254	6	15	-	-	PUNCT
gs-4254	6	16	rich	rich	ADJ
gs-4254	6	17	blood	blood	NOUN
gs-4254	6	18	to	to	ADP
gs-4254	6	19	tissues	tissue	NOUN
gs-4254	6	20	and	and	CCONJ
gs-4254	6	21	organs	organ	NOUN
gs-4254	6	22	.	.	PUNCT
gs-4254	7	1	shock	shock	NOUN
gs-4254	7	2	leads	lead	VERB
gs-4254	7	3	to	to	ADP
gs-4254	7	4	a	a	DET
gs-4254	7	5	dangerous	dangerous	ADJ
gs-4254	7	6	drop	drop	NOUN
gs-4254	7	7	in	in	ADP
gs-4254	7	8	blood	blood	NOUN
gs-4254	7	9	pressure	pressure	NOUN
gs-4254	7	10	and	and	CCONJ
gs-4254	7	11	reduced	reduce	VERB
gs-4254	7	12	blood	blood	NOUN
gs-4254	7	13	flow	flow	NOUN
gs-4254	7	14	.	.	PUNCT
gs-4254	8	1	the	the	DET
gs-4254	8	2	underlying	underlying	ADJ
gs-4254	8	3	pathophysiological	pathophysiological	ADJ
gs-4254	8	4	mechanism	mechanism	NOUN
gs-4254	8	5	of	of	ADP
gs-4254	8	6	shock	shock	NOUN
gs-4254	8	7	is	be	AUX
gs-4254	8	8	widespread	widespread	ADJ
gs-4254	8	9	circulatory	circulatory	ADJ
gs-4254	8	10	failure	failure	NOUN
gs-4254	8	11	resulting	result	VERB
gs-4254	8	12	in	in	ADP
gs-4254	8	13	inadequate	inadequate	ADJ
gs-4254	8	14	tissue	tissue	NOUN
gs-4254	8	15	perfusion	perfusion	NOUN
gs-4254	8	16	and	and	CCONJ
gs-4254	8	17	oxygen	oxygen	NOUN
gs-4254	8	18	delivery	delivery	NOUN
gs-4254	8	19	.	.	PUNCT
gs-4254	9	1	shock	shock	NOUN
gs-4254	9	2	can	can	AUX
gs-4254	9	3	be	be	AUX
gs-4254	9	4	classified	classify	VERB
gs-4254	9	5	into	into	ADP
gs-4254	9	6	four	four	NUM
gs-4254	9	7	main	main	ADJ
gs-4254	9	8	types	type	NOUN
gs-4254	9	9	:	:	PUNCT
gs-4254	9	10	hypovolemic	hypovolemic	ADJ
gs-4254	9	11	,	,	PUNCT
gs-4254	9	12	cardiogenic	cardiogenic	ADJ
gs-4254	9	13	,	,	PUNCT
gs-4254	9	14	obstructive	obstructive	ADJ
gs-4254	9	15	,	,	PUNCT
gs-4254	9	16	and	and	CCONJ
gs-4254	9	17	distributive	distributive	ADJ
gs-4254	9	18	.	.	PUNCT
gs-4254	10	1	the	the	DET
gs-4254	10	2	distributive	distributive	ADJ
gs-4254	10	3	category	category	NOUN
gs-4254	10	4	includes	include	VERB
gs-4254	10	5	septic	septic	ADJ
gs-4254	10	6	,	,	PUNCT
gs-4254	10	7	anaphylactic	anaphylactic	ADJ
gs-4254	10	8	,	,	PUNCT
gs-4254	10	9	and	and	CCONJ
gs-4254	10	10	neurogenic	neurogenic	ADJ
gs-4254	10	11	shock	shock	NOUN
gs-4254	10	12	.	.	PUNCT
gs-4254	11	1	among	among	ADP
gs-4254	11	2	these	these	PRON
gs-4254	11	3	,	,	PUNCT
gs-4254	11	4	septic	septic	ADJ
gs-4254	11	5	shock	shock	NOUN
gs-4254	11	6	is	be	AUX
gs-4254	11	7	the	the	DET
gs-4254	11	8	most	most	ADV
gs-4254	11	9	common	common	ADJ
gs-4254	11	10	in	in	ADP
gs-4254	11	11	intensive	intensive	ADJ
gs-4254	11	12	care	care	NOUN
gs-4254	11	13	units	unit	NOUN
gs-4254	11	14	,	,	PUNCT
gs-4254	11	15	followed	follow	VERB
gs-4254	11	16	by	by	ADP
gs-4254	11	17	cardiogenic	cardiogenic	ADJ
gs-4254	11	18	and	and	CCONJ
gs-4254	11	19	hypovolemic	hypovolemic	ADJ
gs-4254	11	20	shock	shock	NOUN
gs-4254	11	21	.	.	PUNCT
gs-4254	12	1	when	when	SCONJ
gs-4254	12	2	oxygen	oxygen	NOUN
gs-4254	12	3	supply	supply	NOUN
gs-4254	12	4	becomes	become	VERB
gs-4254	12	5	inadequate	inadequate	ADJ
gs-4254	12	6	,	,	PUNCT
gs-4254	12	7	the	the	DET
gs-4254	12	8	body	body	NOUN
gs-4254	12	9	initiates	initiate	VERB
gs-4254	12	10	several	several	ADJ
gs-4254	12	11	adaptive	adaptive	ADJ
gs-4254	12	12	mechanisms	mechanism	NOUN
gs-4254	12	13	to	to	PART
gs-4254	12	14	maintain	maintain	VERB
gs-4254	12	15	perfusion	perfusion	NOUN
gs-4254	12	16	pressure	pressure	NOUN
gs-4254	12	17	and	and	CCONJ
gs-4254	12	18	oxygen	oxygen	NOUN
gs-4254	12	19	delivery	delivery	NOUN
gs-4254	12	20	.	.	PUNCT
gs-4254	13	1	this	this	DET
gs-4254	13	2	compensatory	compensatory	ADJ
gs-4254	13	3	period	period	NOUN
gs-4254	13	4	is	be	AUX
gs-4254	13	5	known	know	VERB
gs-4254	13	6	as	as	ADP
gs-4254	13	7	compensated	compensated	ADJ
gs-4254	13	8	shock	shock	NOUN
gs-4254	13	9	,	,	PUNCT
gs-4254	13	10	during	during	ADP
gs-4254	13	11	which	which	PRON
gs-4254	13	12	early	early	ADJ
gs-4254	13	13	clinical	clinical	ADJ
gs-4254	13	14	signs	sign	NOUN
gs-4254	13	15	may	may	AUX
gs-4254	13	16	be	be	AUX
gs-4254	13	17	detected	detect	VERB
gs-4254	13	18	.	.	PUNCT
gs-4254	14	1	the	the	DET
gs-4254	14	2	initial	initial	ADJ
gs-4254	14	3	response	response	NOUN
gs-4254	14	4	to	to	ADP
gs-4254	14	5	hypoperfusion	hypoperfusion	NOUN
gs-4254	14	6	involves	involve	VERB
gs-4254	14	7	activation	activation	NOUN
gs-4254	14	8	of	of	ADP
gs-4254	14	9	the	the	DET
gs-4254	14	10	baroreceptor	baroreceptor	NOUN
gs-4254	14	11	reflex	reflex	NOUN
gs-4254	14	12	and	and	CCONJ
gs-4254	14	13	the	the	DET
gs-4254	14	14	renin	renin	ADJ
gs-4254	14	15	angiotensin	angiotensin	NOUN
gs-4254	14	16	aldosterone	aldosterone	NOUN
gs-4254	14	17	system	system	NOUN
gs-4254	14	18	.	.	PUNCT
gs-4254	15	1	aldosterone	aldosterone	NOUN
gs-4254	15	2	acts	act	VERB
gs-4254	15	3	on	on	ADP
gs-4254	15	4	the	the	DET
gs-4254	15	5	principal	principal	ADJ
gs-4254	15	6	cells	cell	NOUN
gs-4254	15	7	of	of	ADP
gs-4254	15	8	the	the	DET
gs-4254	15	9	renal	renal	ADJ
gs-4254	15	10	collecting	collect	VERB
gs-4254	15	11	tubules	tubule	NOUN
gs-4254	15	12	to	to	PART
gs-4254	15	13	increase	increase	VERB
gs-4254	15	14	sodium	sodium	NOUN
gs-4254	15	15	reabsorption	reabsorption	NOUN
gs-4254	15	16	,	,	PUNCT
gs-4254	15	17	resulting	result	VERB
gs-4254	15	18	in	in	ADP
gs-4254	15	19	fluid	fluid	ADJ
gs-4254	15	20	retention	retention	NOUN
gs-4254	15	21	and	and	CCONJ
gs-4254	15	22	improved	improve	VERB
gs-4254	15	23	cardiac	cardiac	ADJ
gs-4254	15	24	output	output	NOUN
gs-4254	15	25	.	.	PUNCT
gs-4254	16	1	when	when	SCONJ
gs-4254	16	2	compensatory	compensatory	ADJ
gs-4254	16	3	mechanisms	mechanism	NOUN
gs-4254	16	4	fail	fail	VERB
gs-4254	16	5	and	and	CCONJ
gs-4254	16	6	oxygen	oxygen	NOUN
gs-4254	16	7	delivery	delivery	NOUN
gs-4254	16	8	(	(	PUNCT
gs-4254	16	9	)	)	PUNCT
gs-4254	16	10	declines	decline	VERB
gs-4254	16	11	beyond	beyond	ADP
gs-4254	16	12	a	a	DET
gs-4254	16	13	critical	critical	ADJ
gs-4254	16	14	threshold	threshold	NOUN
gs-4254	16	15	,	,	PUNCT
gs-4254	16	16	shock	shock	NOUN
gs-4254	16	17	progresses	progress	VERB
gs-4254	16	18	to	to	ADP
gs-4254	16	19	the	the	DET
gs-4254	16	20	uncompensated	uncompensated	ADJ
gs-4254	16	21	stage	stage	NOUN
gs-4254	16	22	.	.	PUNCT
gs-4254	17	1	prolonged	prolonged	ADJ
gs-4254	17	2	hypoxia	hypoxia	NOUN
gs-4254	17	3	and	and	CCONJ
gs-4254	17	4	anaerobic	anaerobic	ADJ
gs-4254	17	5	metabolism	metabolism	NOUN
gs-4254	17	6	cause	cause	VERB
gs-4254	17	7	rapid	rapid	ADJ
gs-4254	17	8	clinical	clinical	ADJ
gs-4254	17	9	deterioration	deterioration	NOUN
gs-4254	17	10	.	.	PUNCT
gs-4254	18	1	the	the	DET
gs-4254	18	2	final	final	ADJ
gs-4254	18	3	stage	stage	NOUN
gs-4254	18	4	,	,	PUNCT
gs-4254	18	5	termed	term	VERB
gs-4254	18	6	irreversible	irreversible	ADJ
gs-4254	18	7	or	or	CCONJ
gs-4254	18	8	refractory	refractory	NOUN
gs-4254	18	9	shock	shock	NOUN
gs-4254	18	10	,	,	PUNCT
gs-4254	18	11	is	be	AUX
gs-4254	18	12	typically	typically	ADV
gs-4254	18	13	associated	associate	VERB
gs-4254	18	14	with	with	ADP
gs-4254	18	15	multiple	multiple	ADJ
gs-4254	18	16	organ	organ	NOUN
gs-4254	18	17	dysfunction	dysfunction	NOUN
gs-4254	18	18	syndrome	syndrome	NOUN
gs-4254	18	19	(	(	PUNCT
gs-4254	18	20	mods	mod	NOUN
gs-4254	18	21	)	)	PUNCT
gs-4254	18	22	and	and	CCONJ
gs-4254	18	23	carries	carry	VERB
gs-4254	18	24	a	a	DET
gs-4254	18	25	mortality	mortality	NOUN
gs-4254	18	26	rate	rate	NOUN
gs-4254	18	27	of	of	ADP
gs-4254	18	28	96	96	NUM
gs-4254	18	29	99	99	NUM
gs-4254	18	30	%	%	NOUN
gs-4254	18	31	.	.	PUNCT
gs-4254	19	1	a	a	DET
gs-4254	19	2	common	common	ADJ
gs-4254	19	3	mechanism	mechanism	NOUN
gs-4254	19	4	underlying	underlying	ADJ
gs-4254	19	5	mods	mod	NOUN
gs-4254	19	6	is	be	AUX
gs-4254	19	7	ischemia	ischemia	NOUN
gs-4254	19	8	reperfusion	reperfusion	NOUN
gs-4254	19	9	injury	injury	NOUN
gs-4254	19	10	,	,	PUNCT
gs-4254	19	11	which	which	PRON
gs-4254	19	12	contributes	contribute	VERB
gs-4254	19	13	significantly	significantly	ADV
gs-4254	19	14	to	to	ADP
gs-4254	19	15	mortality	mortality	NOUN
gs-4254	19	16	among	among	ADP
gs-4254	19	17	intensive	intensive	ADJ
gs-4254	19	18	care	care	NOUN
gs-4254	19	19	patients	patient	NOUN
gs-4254	19	20	.	.	PUNCT
gs-4254	20	1	recent	recent	ADJ
gs-4254	20	2	advancements	advancement	NOUN
gs-4254	20	3	in	in	ADP
gs-4254	20	4	understanding	understand	VERB
gs-4254	20	5	shock	shock	NOUN
gs-4254	20	6	pathogenesis	pathogenesis	NOUN
gs-4254	20	7	emphasize	emphasize	VERB
gs-4254	20	8	the	the	DET
gs-4254	20	9	critical	critical	ADJ
gs-4254	20	10	role	role	NOUN
gs-4254	20	11	of	of	ADP
gs-4254	20	12	microcirculatory	microcirculatory	ADJ
gs-4254	20	13	dysfunction	dysfunction	NOUN
gs-4254	20	14	and	and	CCONJ
gs-4254	20	15	endothelial	endothelial	ADJ
gs-4254	20	16	injury	injury	NOUN
gs-4254	20	17	,	,	PUNCT
gs-4254	20	18	even	even	ADV
gs-4254	20	19	when	when	SCONJ
gs-4254	20	20	traditional	traditional	ADJ
gs-4254	20	21	"	"	PUNCT
gs-4254	20	22	macro	macro	NOUN
gs-4254	20	23	"	"	PUNCT
gs-4254	20	24	measures	measure	NOUN
gs-4254	20	25	like	like	ADP
gs-4254	20	26	blood	blood	NOUN
gs-4254	20	27	pressure	pressure	NOUN
gs-4254	20	28	appear	appear	VERB
gs-4254	20	29	stable	stable	ADJ
gs-4254	20	30	.	.	PUNCT
gs-4254	21	1	this	this	PRON
gs-4254	21	2	has	have	AUX
gs-4254	21	3	led	lead	VERB
gs-4254	21	4	to	to	ADP
gs-4254	21	5	the	the	DET
gs-4254	21	6	development	development	NOUN
gs-4254	21	7	of	of	ADP
gs-4254	21	8	new	new	ADJ
gs-4254	21	9	diagnostic	diagnostic	ADJ
gs-4254	21	10	and	and	CCONJ
gs-4254	21	11	therapeutic	therapeutic	ADJ
gs-4254	21	12	strategies	strategy	NOUN
gs-4254	21	13	focused	focus	VERB
gs-4254	21	14	on	on	ADP
gs-4254	21	15	the	the	DET
gs-4254	21	16	cellular	cellular	ADJ
gs-4254	21	17	and	and	CCONJ
gs-4254	21	18	microvascular	microvascular	ADJ
gs-4254	21	19	levels	level	NOUN
gs-4254	21	20	.	.	PUNCT
gs-4254	22	1	keywords	keyword	NOUN
gs-4254	22	2	:	:	PUNCT
gs-4254	22	3	shock	shock	NOUN
gs-4254	22	4	,	,	PUNCT
gs-4254	22	5	hypoperfusion	hypoperfusion	NOUN
gs-4254	22	6	,	,	PUNCT
gs-4254	22	7	oxygen	oxygen	NOUN
gs-4254	22	8	supply	supply	NOUN
gs-4254	22	9	,	,	PUNCT
gs-4254	22	10	hypoxia	hypoxia	NOUN
gs-4254	22	11	,	,	PUNCT
gs-4254	22	12	intensive	intensive	ADJ
gs-4254	22	13	care	care	NOUN