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(x200 H&E) . 6 , (x100 H&E) : , , , , , . . . 7 (x100 H&E)_1 . 7 (x100 H&E) Georgian Scientists/ . 6 N 2, 2024 411 2.4 : - Agilent 7890A GC-G1888 Headspase - - - (5.5 ) - DB -ALC1 (30 x 0.530 X 3 ); DB –ALC2 (30 x 0.530 X 2 ); - 400C, 5 ( ) - 2500C - 3000C 0.8‰ . , , ,,ELISA“ ( - HUMAREADER- ) (GC/MS) : (ELISA ) 25-25 , . 100-100 . 30 . 100-100 30 100- 100 . - Agilent Technologies 7890B GC System /5977A MSD: - Elite 5-MS; 30m X 250 m X 0. 25 m; - 50°C -310°C ( ); - 250°C; - 310°C; – - 1 ; EI - 70 ev; - TIC (40 – 500 Da) - , , , . , : , , , , , , , - , - , - , , , , 5F-AB-PINACA, RSC-4, AKB-48(APINACA), MAM-2201. : . 3. . , . ( , 2006). 72.72%- (89/116) ( ) , 27 . , Georgian Scientists/ . 6 N 2, 2024 412 3.6 ( 1-5 ). 46 , 43 . 56 , 60 . 38 , . . MELAN-A, Syn (50- 46), NSE (50- 44), Vim (50- 42) Ki-67 <5% (50- 24, 26 Ki-67 ) (Jia AH, 2015 ). , (PF Plouin, 2006). , (Badui, 1982). , . , - 14- , : , (Stolk RF, 2013). , (Batisse-Lignier, 2015). , 0.2%- , . : 37 , , : , , , - (LVH). (MR) , LVH, , , , (HCM)- . , . , 4 . , , , , . , LVH- . Georgian Scientists/ . 6 N 2, 2024 413 24 (396 421 g/24 ; - 2-350 g/24 ); (CT) . , . . 6 (143 g/24 ), LVH (14 ). , , (Olmati, 2018). , 2%- (G. Qian, 2014). , , . , , , , , , , . , , , . Georgian Scientists/ . 6 N 2, 2024 414 References 1. Dutt, M., Wehrle, C. J., & Jialal, I. (2022). Physiology, adrenal gland. In StatPearls [Internet]. StatPearls Publishing. 2. , ., , . (2002). Frequency and Types of Traumas in Khevsureti according to the Fossil Material of the High and Late Middle Ages. , (3), 189-215. 3. WHO, (2016). Estimated death by cause, sex and WHO Member State, Department of information evidence and Research. 4. Song JH, Chaudhry FS, Mayo-Smith WW. The incidental adrenal mass on CT: prevalence of adrenal disease in 1,049 consecutive adrenal masses in patients with no known malignancy. AJR Am J Roentgenol. 2008 May; 190(5): 1163-8. [PubMed: 18430826] 5. 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B, 15(12), 1048. - ; - ; - ; LVH - ; MR - ; CT - ; Georgian Scientists/ . 6 N 2, 2024 416 Heart rupture – a complication of adrenal cortical adenoma – case report Elguja Latchkepiani1, Maia Gambarashvili2, Dimitri Kochadze3 1LEPL Levan Samkharauli National Forensic Bureau, Department of Medical Examination Department, Forensic Medical Expert at Living Bodies and Corpses Examination Unit; PhD student of Tbilisi State University; 2 LEPL Levan Samkharauli National Forensic Bureau, Department of Medical Examination Department, Histological Examination Expert; Pathologist; 3PhD student of Tbilisi State Medical University; Doctor of Infectious deseases. Abstract Adrenal adenoma are usually benign neoplasms arising from the cortex of adrenal gland. Most adenomas do not produce hormones, but can produce excessive amounts of adrenocortical hormones. However, cases have been described when these types of tumors produce catecholamines, which are characterized by cardiotoxicity. Most studies have focused on adrenal medulla tumors that develop as a result of degeneration of chromaffin cells and neuros. Most of them synthesize and secrete catecholamines. This case of adrenal cortical adenoma discussed above is a functional tumor, the chronic hormonal activity of which was manifested by hypertrophy of cardiomyocytes, the formation of infarction, which led us to the final result, called heart rupture. Key words: Rupture; Autopsy; Adenoma; Incidentaloma; Adrenal gland.