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Main causes of intelligence decrease and prospects for treatment Jaba Tkemaladze1 1 Research director, Longevity Clinic jtkemaladze@longevity.ge Abstract The association of leukocyte telomere length (LTL) with structural and cognitive changes in the brain suggests a specific canonical effect, particularly in the elderly and in women. Unfortunately, the feedback does not appear - brain training exercises do not increase the length of telomeres. It turns out that intelligence is almost entirely due to genetics, not to teaching or any other training. Today, with gene editing, it is possible to increase the length of telomeres, while shortening it would pose a threat to the brain. Key words: intelligence; telomere length; cognition; senescence; aging