id sid tid token lemma pos ghmj-113 1 1 cite cite VERB ghmj-113 1 2     SPACE ghmj-113 1 3 this this DET ghmj-113 1 4     SPACE ghmj-113 1 5 article article NOUN ghmj-113 1 6     SPACE ghmj-113 1 7 as as ADP ghmj-113 1 8     SPACE ghmj-113 1 9 sawasdee sawasdee PROPN ghmj-113 1 10     SPACE ghmj-113 1 11 k k PROPN ghmj-113 1 12 , , PUNCT ghmj-113 1 13     SPACE ghmj-113 1 14 choksawad choksawad VERB ghmj-113 1 15     SPACE ghmj-113 1 16 p p PROPN ghmj-113 1 17 , , PUNCT ghmj-113 1 18     SPACE ghmj-113 1 19 pimcharoen pimcharoen NOUN ghmj-113 1 20     SPACE ghmj-113 1 21 s s PROPN ghmj-113 1 22 , , PUNCT ghmj-113 1 23     SPACE ghmj-113 1 24 prapainop prapainop NOUN ghmj-113 1 25     SPACE ghmj-113 1 26 k. k. PROPN ghmj-113 1 27     SPACE ghmj-113 1 28 development development NOUN ghmj-113 1 29     SPACE ghmj-113 1 30 of of ADP ghmj-113 1 31     SPACE ghmj-113 1 32 size‐tunable size‐tunable NOUN ghmj-113 1 33     SPACE ghmj-113 1 34 polymeric polymeric ADJ ghmj-113 1 35     SPACE ghmj-113 1 36 nanoparticles nanoparticle NOUN ghmj-113 1 37     SPACE ghmj-113 1 38 for for ADP ghmj-113 1 39     SPACE ghmj-113 1 40 drug drug NOUN ghmj-113 1 41     SPACE ghmj-113 1 42 delivery delivery NOUN ghmj-113 1 43     SPACE ghmj-113 1 44 applications application NOUN ghmj-113 1 45 . . PUNCT ghmj-113 1 46     SPACE ghmj-113 2 1 global global ADJ ghmj-113 2 2     SPACE ghmj-113 2 3 health health NOUN ghmj-113 2 4     SPACE ghmj-113 2 5 management management NOUN ghmj-113 2 6     SPACE ghmj-113 2 7 journal journal NOUN ghmj-113 2 8 . . PUNCT ghmj-113 2 9     SPACE ghmj-113 2 10 2017 2017 NUM ghmj-113 2 11 ; ; PUNCT ghmj-113 2 12     SPACE ghmj-113 2 13 1(2 1(2 NUM ghmj-113 2 14 ): ): PUNCT ghmj-113 2 15     SPACE ghmj-113 2 16 31‐6 31‐6 NUM ghmj-113 2 17 . . PUNCT ghmj-113 2 18         SPACE ghmj-113 2 19 global global ADJ ghmj-113 2 20     SPACE ghmj-113 2 21 health health NOUN ghmj-113 2 22     SPACE ghmj-113 2 23 management management NOUN ghmj-113 2 24     SPACE ghmj-113 2 25 journal journal NOUN ghmj-113 2 26     SPACE ghmj-113 2 27 www.publications.inschool.id www.publications.inschool.id NOUN ghmj-113 2 28     SPACE ghmj-113 2 29 published publish VERB ghmj-113 2 30     SPACE ghmj-113 2 31 by by ADP ghmj-113 2 32     SPACE ghmj-113 2 33 original original ADJ ghmj-113 2 34 research research NOUN ghmj-113 2 35 article article NOUN ghmj-113 2 36 issn issn VERB ghmj-113 2 37 2580 2580 NUM ghmj-113 2 38 - - SYM ghmj-113 2 39 9296 9296 NUM ghmj-113 2 40 ( ( PUNCT ghmj-113 2 41 online online ADJ ghmj-113 2 42 ) ) PUNCT ghmj-113 2 43 development development NOUN ghmj-113 2 44 of of ADP ghmj-113 2 45 size size NOUN ghmj-113 2 46 - - PUNCT ghmj-113 2 47 tunable tunable NOUN ghmj-113 2 48 polymeric polymeric ADJ ghmj-113 2 49 nanoparticles nanoparticle NOUN ghmj-113 2 50 for for ADP ghmj-113 2 51 drug drug NOUN ghmj-113 2 52 delivery delivery NOUN ghmj-113 2 53 applications application NOUN ghmj-113 2 54 komkrich komkrich VERB ghmj-113 2 55 sawasdee sawasdee PROPN ghmj-113 2 56 1 1 NUM ghmj-113 2 57 , , PUNCT ghmj-113 2 58 ployphailin ployphailin NOUN ghmj-113 2 59 choksawad choksawad PROPN ghmj-113 2 60 1 1 NUM ghmj-113 2 61 , , PUNCT ghmj-113 2 62 sopida sopida NOUN ghmj-113 2 63 pimcharoen pimcharoen NOUN ghmj-113 2 64 2 2 NUM ghmj-113 2 65 , , PUNCT ghmj-113 2 66 kanlaya kanlaya NOUN ghmj-113 2 67 prapainop1 prapainop1 NOUN ghmj-113 2 68 , , PUNCT ghmj-113 2 69 * * SYM ghmj-113 2 70 1 1 NUM ghmj-113 2 71 department department NOUN ghmj-113 2 72 of of ADP ghmj-113 2 73 biochemistry biochemistry NOUN ghmj-113 2 74 , , PUNCT ghmj-113 2 75 faculty faculty NOUN ghmj-113 2 76 of of ADP ghmj-113 2 77 science science NOUN ghmj-113 2 78 , , PUNCT ghmj-113 2 79 mahidol mahidol PROPN ghmj-113 2 80 university university PROPN ghmj-113 2 81 , , PUNCT ghmj-113 2 82 bangkok bangkok PROPN ghmj-113 2 83 , , PUNCT ghmj-113 2 84 thailand thailand PROPN ghmj-113 2 85 . . PROPN ghmj-113 2 86 2 2 NUM ghmj-113 2 87 samsenwittayalai samsenwittayalai NOUN ghmj-113 2 88 school school NOUN ghmj-113 2 89 , , PUNCT ghmj-113 2 90 rama rama PROPN ghmj-113 2 91 vi vi PROPN ghmj-113 2 92 road road PROPN ghmj-113 2 93 , , PUNCT ghmj-113 2 94 bangkok bangkok PROPN ghmj-113 2 95 , , PUNCT ghmj-113 2 96 thailand thailand PROPN ghmj-113 2 97 . . PUNCT ghmj-113 3 1 * * PUNCT ghmj-113 3 2 corresponding correspond VERB ghmj-113 3 3 author author NOUN ghmj-113 3 4 . . PUNCT ghmj-113 4 1 email email NOUN ghmj-113 4 2 : : PUNCT ghmj-113 5 1 kanlaya.pra@mahidol.edu kanlaya.pra@mahidol.edu PROPN ghmj-113 5 2 article article NOUN ghmj-113 5 3 info info NOUN ghmj-113 5 4 abstract abstract ADJ ghmj-113 5 5 article article NOUN ghmj-113 5 6 history history NOUN ghmj-113 5 7 : : PUNCT ghmj-113 5 8 submitted submit VERB ghmj-113 5 9 16 16 NUM ghmj-113 5 10 october october PROPN ghmj-113 5 11 2017 2017 NUM ghmj-113 5 12 accepted accept VERB ghmj-113 5 13 27 27 NUM ghmj-113 5 14 october october PROPN ghmj-113 5 15 2017 2017 NUM ghmj-113 5 16 background background NOUN ghmj-113 5 17 : : PUNCT ghmj-113 5 18 poly poly ADJ ghmj-113 5 19 lactide lactide NOUN ghmj-113 5 20 - - PUNCT ghmj-113 5 21 co co NOUN ghmj-113 5 22 - - NOUN ghmj-113 5 23 glycolide glycolide ADJ ghmj-113 5 24 ( ( PUNCT ghmj-113 5 25 plga plga NOUN ghmj-113 5 26 ) ) PUNCT ghmj-113 5 27 nanoparticles nanoparticle NOUN ghmj-113 5 28 ( ( PUNCT ghmj-113 5 29 nps nps PROPN ghmj-113 5 30 ) ) PUNCT ghmj-113 5 31 have have AUX ghmj-113 5 32 been be AUX ghmj-113 5 33 widely widely ADV ghmj-113 5 34 used use VERB ghmj-113 5 35 in in ADP ghmj-113 5 36 drug drug NOUN ghmj-113 5 37 delivery delivery NOUN ghmj-113 5 38 applications application NOUN ghmj-113 5 39 because because SCONJ ghmj-113 5 40 of of ADP ghmj-113 5 41 their their PRON ghmj-113 5 42 excellent excellent ADJ ghmj-113 5 43 properties property NOUN ghmj-113 5 44 such such ADJ ghmj-113 5 45 as as ADP ghmj-113 5 46 biocompatibility biocompatibility NOUN ghmj-113 5 47 , , PUNCT ghmj-113 5 48 and and CCONJ ghmj-113 5 49 biodegradability biodegradability NOUN ghmj-113 5 50 along along ADP ghmj-113 5 51 with with ADP ghmj-113 5 52 the the DET ghmj-113 5 53 ability ability NOUN ghmj-113 5 54 to to PART ghmj-113 5 55 deliver deliver VERB ghmj-113 5 56 hydrophobic hydrophobic NOUN ghmj-113 5 57 drugs drug NOUN ghmj-113 5 58 , , PUNCT ghmj-113 5 59 increase increase VERB ghmj-113 5 60 drug drug NOUN ghmj-113 5 61 bioavailability bioavailability NOUN ghmj-113 5 62 and and CCONJ ghmj-113 5 63 improve improve VERB ghmj-113 5 64 drug drug NOUN ghmj-113 5 65 absorption absorption NOUN ghmj-113 5 66 to to ADP ghmj-113 5 67 targeted target VERB ghmj-113 5 68 cells cell NOUN ghmj-113 5 69 in in ADP ghmj-113 5 70 both both CCONJ ghmj-113 5 71 oral oral ADJ ghmj-113 5 72 and and CCONJ ghmj-113 5 73 parenteral parenteral ADJ ghmj-113 5 74 administrations administration NOUN ghmj-113 5 75 . . PUNCT ghmj-113 6 1 the the DET ghmj-113 6 2 plga plga NOUN ghmj-113 6 3 nps nps PROPN ghmj-113 6 4 can can AUX ghmj-113 6 5 be be AUX ghmj-113 6 6 synthesized synthesize VERB ghmj-113 6 7 using use VERB ghmj-113 6 8 an an DET ghmj-113 6 9 emulsion emulsion NOUN ghmj-113 6 10 solvent solvent NOUN ghmj-113 6 11 evaporation evaporation NOUN ghmj-113 6 12 method method NOUN ghmj-113 6 13 . . PUNCT ghmj-113 7 1 each each DET ghmj-113 7 2 parameter parameter NOUN ghmj-113 7 3 during during ADP ghmj-113 7 4 synthesis synthesis NOUN ghmj-113 7 5 plays play VERB ghmj-113 7 6 a a DET ghmj-113 7 7 role role NOUN ghmj-113 7 8 in in ADP ghmj-113 7 9 the the DET ghmj-113 7 10 formation formation NOUN ghmj-113 7 11 of of ADP ghmj-113 7 12 nanoparticles nanoparticle NOUN ghmj-113 7 13 and and CCONJ ghmj-113 7 14 can can AUX ghmj-113 7 15 affect affect VERB ghmj-113 7 16 np np PRON ghmj-113 7 17 size size NOUN ghmj-113 7 18 ; ; PUNCT ghmj-113 7 19 important important ADJ ghmj-113 7 20 factors factor NOUN ghmj-113 7 21 for for ADP ghmj-113 7 22 successful successful ADJ ghmj-113 7 23 development development NOUN ghmj-113 7 24 of of ADP ghmj-113 7 25 a a DET ghmj-113 7 26 drug drug NOUN ghmj-113 7 27 delivery delivery NOUN ghmj-113 7 28 system system NOUN ghmj-113 7 29 . . PUNCT ghmj-113 8 1 aims aim VERB ghmj-113 8 2 : : PUNCT ghmj-113 8 3 the the DET ghmj-113 8 4 aim aim NOUN ghmj-113 8 5 of of ADP ghmj-113 8 6 this this DET ghmj-113 8 7 study study NOUN ghmj-113 8 8 was be AUX ghmj-113 8 9 to to PART ghmj-113 8 10 prepare prepare VERB ghmj-113 8 11 different different ADJ ghmj-113 8 12 sizes size NOUN ghmj-113 8 13 of of ADP ghmj-113 8 14 plga plga NOUN ghmj-113 8 15 nps nps PROPN ghmj-113 8 16 by by ADP ghmj-113 8 17 investigation investigation NOUN ghmj-113 8 18 of of ADP ghmj-113 8 19 four four NUM ghmj-113 8 20 factors factor NOUN ghmj-113 8 21 ( ( PUNCT ghmj-113 8 22 molecular molecular ADJ ghmj-113 8 23 weight weight NOUN ghmj-113 8 24 , , PUNCT ghmj-113 8 25 mw mw PROPN ghmj-113 8 26 ) ) PUNCT ghmj-113 8 27 of of ADP ghmj-113 8 28 plga plga NOUN ghmj-113 8 29 , , PUNCT ghmj-113 8 30 emulsifier emulsifier NOUN ghmj-113 8 31 concentrations concentration NOUN ghmj-113 8 32 , , PUNCT ghmj-113 8 33 organic organic ADJ ghmj-113 8 34 solvent solvent ADJ ghmj-113 8 35 type type NOUN ghmj-113 8 36 and and CCONJ ghmj-113 8 37 power power NOUN ghmj-113 8 38 of of ADP ghmj-113 8 39 ultrasonication ultrasonication NOUN ghmj-113 8 40 ) ) PUNCT ghmj-113 8 41 involved involve VERB ghmj-113 8 42 in in ADP ghmj-113 8 43 plga plga NOUN ghmj-113 8 44 nanoparticle nanoparticle NOUN ghmj-113 8 45 synthesis synthesis NOUN ghmj-113 8 46 . . PUNCT ghmj-113 9 1 methods method NOUN ghmj-113 9 2 : : PUNCT ghmj-113 9 3 plga plga VERB ghmj-113 9 4 nanoparticles nanoparticle NOUN ghmj-113 9 5 were be AUX ghmj-113 9 6 prepared prepare VERB ghmj-113 9 7 by by ADP ghmj-113 9 8 an an DET ghmj-113 9 9 emulsion emulsion NOUN ghmj-113 9 10 solvent solvent NOUN ghmj-113 9 11 evaporation evaporation NOUN ghmj-113 9 12 method method NOUN ghmj-113 9 13 . . PUNCT ghmj-113 10 1 size size NOUN ghmj-113 10 2 and and CCONJ ghmj-113 10 3 size size NOUN ghmj-113 10 4 distribution distribution NOUN ghmj-113 10 5 were be AUX ghmj-113 10 6 analyzed analyze VERB ghmj-113 10 7 by by ADP ghmj-113 10 8 dynamic dynamic ADJ ghmj-113 10 9 light light NOUN ghmj-113 10 10 scattering scattering NOUN ghmj-113 10 11 and and CCONJ ghmj-113 10 12 polydispersity polydispersity NOUN ghmj-113 10 13 index index NOUN ghmj-113 10 14 ( ( PUNCT ghmj-113 10 15 pdi pdi PROPN ghmj-113 10 16 ) ) PUNCT ghmj-113 10 17 . . PUNCT ghmj-113 11 1 results result NOUN ghmj-113 11 2 : : PUNCT ghmj-113 11 3 the the DET ghmj-113 11 4 effect effect NOUN ghmj-113 11 5 of of ADP ghmj-113 11 6 four four NUM ghmj-113 11 7 parameters parameter NOUN ghmj-113 11 8 : : PUNCT ghmj-113 11 9 plga plga NOUN ghmj-113 11 10 mw mw NOUN ghmj-113 11 11 , , PUNCT ghmj-113 11 12 emulsifier emulsifier NOUN ghmj-113 11 13 concentrations concentration NOUN ghmj-113 11 14 , , PUNCT ghmj-113 11 15 solvent solvent ADJ ghmj-113 11 16 types type NOUN ghmj-113 11 17 , , PUNCT ghmj-113 11 18 and and CCONJ ghmj-113 11 19 amplitude amplitude NOUN ghmj-113 11 20 of of ADP ghmj-113 11 21 ultrasonication ultrasonication NOUN ghmj-113 11 22 on on ADP ghmj-113 11 23 plga plga NOUN ghmj-113 11 24 nps nps PROPN ghmj-113 11 25 preparation preparation NOUN ghmj-113 11 26 were be AUX ghmj-113 11 27 evaluated evaluate VERB ghmj-113 11 28 . . PUNCT ghmj-113 12 1 changing change VERB ghmj-113 12 2 one one NUM ghmj-113 12 3 parameter parameter NOUN ghmj-113 12 4 results result NOUN ghmj-113 12 5 in in ADP ghmj-113 12 6 different different ADJ ghmj-113 12 7 sizes size NOUN ghmj-113 12 8 of of ADP ghmj-113 12 9 plga plga NOUN ghmj-113 12 10 nps nps PROPN ghmj-113 12 11 that that PRON ghmj-113 12 12 varied vary VERB ghmj-113 12 13 from from ADP ghmj-113 12 14 150300 150300 NUM ghmj-113 12 15 nm nm NOUN ghmj-113 12 16 . . PUNCT ghmj-113 13 1 pdi pdi NOUN ghmj-113 13 2 which which PRON ghmj-113 13 3 is be AUX ghmj-113 13 4 an an DET ghmj-113 13 5 indicator indicator NOUN ghmj-113 13 6 for for ADP ghmj-113 13 7 determination determination NOUN ghmj-113 13 8 of of ADP ghmj-113 13 9 size size NOUN ghmj-113 13 10 distribution distribution NOUN ghmj-113 13 11 of of ADP ghmj-113 13 12 nps nps PROPN ghmj-113 13 13 , , PUNCT ghmj-113 13 14 varied varied ADJ ghmj-113 13 15 with with ADP ghmj-113 13 16 an an DET ghmj-113 13 17 overall overall ADJ ghmj-113 13 18 value value NOUN ghmj-113 13 19 < < X ghmj-113 13 20 0.2 0.2 NUM ghmj-113 13 21 . . PUNCT ghmj-113 14 1 conclusion conclusion NOUN ghmj-113 14 2 : : PUNCT ghmj-113 14 3 mw mw X ghmj-113 14 4 of of ADP ghmj-113 14 5 plga plga NOUN ghmj-113 14 6 polymer polymer NOUN ghmj-113 14 7 , , PUNCT ghmj-113 14 8 emulsifier emulsifier NOUN ghmj-113 14 9 concentration concentration NOUN ghmj-113 14 10 , , PUNCT ghmj-113 14 11 type type NOUN ghmj-113 14 12 of of ADP ghmj-113 14 13 organic organic ADJ ghmj-113 14 14 solvent solvent NOUN ghmj-113 14 15 and and CCONJ ghmj-113 14 16 power power NOUN ghmj-113 14 17 of of ADP ghmj-113 14 18 ultrasonication ultrasonication NOUN ghmj-113 14 19 affect affect VERB ghmj-113 14 20 the the DET ghmj-113 14 21 size size NOUN ghmj-113 14 22 and and CCONJ ghmj-113 14 23 size size NOUN ghmj-113 14 24 distribution distribution NOUN ghmj-113 14 25 of of ADP ghmj-113 14 26 plga plga NOUN ghmj-113 14 27 nps nps PROPN ghmj-113 14 28 . . PUNCT ghmj-113 15 1 keywords keyword NOUN ghmj-113 15 2 : : PUNCT ghmj-113 15 3 drug drug NOUN ghmj-113 15 4 delivery delivery NOUN ghmj-113 15 5 polymeric polymeric ADJ ghmj-113 15 6 nanoparticles nanoparticle NOUN ghmj-113 15 7 tunable tunable ADJ ghmj-113 15 8 size size NOUN ghmj-113 15 9 of of ADP ghmj-113 15 10 nanoparticles nanoparticle NOUN ghmj-113 15 11 © © PROPN ghmj-113 15 12 2017 2017 NUM ghmj-113 15 13 publications publication NOUN ghmj-113 15 14 of of ADP ghmj-113 15 15 yayasan yayasan PROPN ghmj-113 15 16 aliansi aliansi PROPN ghmj-113 15 17 cendekiawan cendekiawan PROPN ghmj-113 15 18 indonesia indonesia PROPN ghmj-113 15 19 thailand thailand PROPN ghmj-113 15 20 this this PRON ghmj-113 15 21 is be AUX ghmj-113 15 22 an an DET ghmj-113 15 23 open open ADJ ghmj-113 15 24 access access NOUN ghmj-113 15 25 following follow VERB ghmj-113 15 26 creative creative ADJ ghmj-113 15 27 commons common NOUN ghmj-113 15 28 license license NOUN ghmj-113 15 29 deed deed NOUN ghmj-113 15 30 – – PUNCT ghmj-113 15 31 attribution attribution NOUN ghmj-113 15 32 - - PUNCT ghmj-113 15 33 noncommercial noncommercial ADJ ghmj-113 15 34 - - PUNCT ghmj-113 15 35 sharealike sharealike ADJ ghmj-113 15 36 4.0 4.0 NUM ghmj-113 15 37 international international ADJ ghmj-113 15 38 ( ( PUNCT ghmj-113 15 39 cc cc NOUN ghmj-113 15 40 by by ADP ghmj-113 15 41 - - PUNCT ghmj-113 15 42 nc nc PROPN ghmj-113 15 43 - - PUNCT ghmj-113 15 44 sa sa PROPN ghmj-113 15 45 4.0 4.0 NUM ghmj-113 15 46 ) ) PUNCT ghmj-113 15 47 introduction introduction NOUN ghmj-113 15 48 cancer cancer NOUN ghmj-113 15 49 is be AUX ghmj-113 15 50 a a DET ghmj-113 15 51 worldwide worldwide ADJ ghmj-113 15 52 health health NOUN ghmj-113 15 53 problem problem NOUN ghmj-113 15 54 with with ADP ghmj-113 15 55 millions million NOUN ghmj-113 15 56 of of ADP ghmj-113 15 57 people people NOUN ghmj-113 15 58 suffering suffer VERB ghmj-113 15 59 from from ADP ghmj-113 15 60 this this DET ghmj-113 15 61 disease disease NOUN ghmj-113 15 62 in in ADP ghmj-113 15 63 both both CCONJ ghmj-113 15 64 economically economically ADV ghmj-113 15 65 developed develop VERB ghmj-113 15 66 countries country NOUN ghmj-113 15 67 and and CCONJ ghmj-113 15 68 developing develop VERB ghmj-113 15 69 countries country NOUN ghmj-113 15 70 [ [ X ghmj-113 15 71 1 1 NUM ghmj-113 15 72 ] ] PUNCT ghmj-113 15 73 . . PUNCT ghmj-113 16 1 the the DET ghmj-113 16 2 current current ADJ ghmj-113 16 3 strategies strategy NOUN ghmj-113 16 4 for for ADP ghmj-113 16 5 treatment treatment NOUN ghmj-113 16 6 of of ADP ghmj-113 16 7 cancer cancer NOUN ghmj-113 16 8 include include VERB ghmj-113 16 9 surgery surgery NOUN ghmj-113 16 10 , , PUNCT ghmj-113 16 11 radiation radiation NOUN ghmj-113 16 12 , , PUNCT ghmj-113 16 13 immunotherapy immunotherapy NOUN ghmj-113 16 14 or or CCONJ ghmj-113 16 15 chemotherapy chemotherapy NOUN ghmj-113 16 16 . . PUNCT ghmj-113 17 1 the the DET ghmj-113 17 2 chemotherapeutic chemotherapeutic ADJ ghmj-113 17 3 drug drug NOUN ghmj-113 17 4 is be AUX ghmj-113 17 5 administered administer VERB ghmj-113 17 6 intravenously intravenously ADV ghmj-113 17 7 can can AUX ghmj-113 17 8 spread spread VERB ghmj-113 17 9 to to PART ghmj-113 17 10 accumulate accumulate VERB ghmj-113 17 11 in in ADP ghmj-113 17 12 offtargeted offtargeted ADJ ghmj-113 17 13 tissues tissue NOUN ghmj-113 17 14 or or CCONJ ghmj-113 17 15 organs organ NOUN ghmj-113 17 16 leading lead VERB ghmj-113 17 17 to to ADP ghmj-113 17 18 undesirable undesirable ADJ ghmj-113 17 19 side side NOUN ghmj-113 17 20 effects effect NOUN ghmj-113 17 21 . . PUNCT ghmj-113 18 1 to to PART ghmj-113 18 2 solve solve VERB ghmj-113 18 3 these these DET ghmj-113 18 4 problems problem NOUN ghmj-113 18 5 , , PUNCT ghmj-113 18 6 anti anti ADJ ghmj-113 18 7 - - ADJ ghmj-113 18 8 cancer cancer ADJ ghmj-113 18 9 drug drug NOUN ghmj-113 18 10 loaded load VERB ghmj-113 18 11 nanoparticles nanoparticle NOUN ghmj-113 18 12 have have AUX ghmj-113 18 13 gained gain VERB ghmj-113 18 14 extensive extensive ADJ ghmj-113 18 15 attention attention NOUN ghmj-113 18 16 to to PART ghmj-113 18 17 use use VERB ghmj-113 18 18 as as ADP ghmj-113 18 19 an an DET ghmj-113 18 20 effective effective ADJ ghmj-113 18 21 drug drug NOUN ghmj-113 18 22 delivery delivery NOUN ghmj-113 18 23 system system NOUN ghmj-113 18 24 to to ADP ghmj-113 18 25 specific specific ADJ ghmj-113 18 26 target target NOUN ghmj-113 18 27 sites site NOUN ghmj-113 18 28 [ [ X ghmj-113 18 29 1 1 NUM ghmj-113 18 30 , , PUNCT ghmj-113 18 31 2 2 NUM ghmj-113 18 32 ] ] PUNCT ghmj-113 18 33 . . PUNCT ghmj-113 19 1 polymeric polymeric PROPN ghmj-113 19 2 nps nps PROPN ghmj-113 19 3 have have VERB ghmj-113 19 4 unique unique ADJ ghmj-113 19 5 properties property NOUN ghmj-113 19 6 including include VERB ghmj-113 19 7 stability stability NOUN ghmj-113 19 8 , , PUNCT ghmj-113 19 9 biocompatibility biocompatibility NOUN ghmj-113 19 10 and and CCONJ ghmj-113 19 11 ease ease NOUN ghmj-113 19 12 of of ADP ghmj-113 19 13 surface surface NOUN ghmj-113 19 14 chemistry chemistry NOUN ghmj-113 19 15 modification modification NOUN ghmj-113 19 16 [ [ X ghmj-113 19 17 3 3 NUM ghmj-113 19 18 , , PUNCT ghmj-113 19 19 4 4 NUM ghmj-113 19 20 ] ] PUNCT ghmj-113 19 21 . . PUNCT ghmj-113 20 1 therefore therefore ADV ghmj-113 20 2 these these DET ghmj-113 20 3 nanoparticles nanoparticle NOUN ghmj-113 20 4 have have AUX ghmj-113 20 5 been be AUX ghmj-113 20 6 used use VERB ghmj-113 20 7 in in ADP ghmj-113 20 8 drug drug NOUN ghmj-113 20 9 delivery delivery NOUN ghmj-113 20 10 global global ADJ ghmj-113 20 11     SPACE ghmj-113 20 12 health health NOUN ghmj-113 20 13     SPACE ghmj-113 20 14 management management NOUN ghmj-113 20 15     SPACE ghmj-113 20 16 journal journal NOUN ghmj-113 20 17 , , PUNCT ghmj-113 20 18     SPACE ghmj-113 20 19 2017 2017 NUM ghmj-113 20 20 , , PUNCT ghmj-113 20 21     SPACE ghmj-113 20 22 vol vol NOUN ghmj-113 20 23 . . PUNCT ghmj-113 20 24     SPACE ghmj-113 21 1 1 1 NUM ghmj-113 21 2 , , PUNCT ghmj-113 21 3     SPACE ghmj-113 21 4 no no INTJ ghmj-113 21 5 . . PUNCT ghmj-113 21 6     SPACE ghmj-113 21 7 2 2 NUM ghmj-113 21 8     SPACE ghmj-113 21 9 32 32 NUM ghmj-113 21 10           SPACE ghmj-113 21 11 systems system NOUN ghmj-113 21 12 to to PART ghmj-113 21 13 protect protect VERB ghmj-113 21 14 drugs drug NOUN ghmj-113 21 15 from from ADP ghmj-113 21 16 bioand bioand X ghmj-113 21 17 chemical chemical NOUN ghmj-113 21 18 degradation degradation NOUN ghmj-113 21 19 which which PRON ghmj-113 21 20 also also ADV ghmj-113 21 21 help help VERB ghmj-113 21 22 to to PART ghmj-113 21 23 increase increase VERB ghmj-113 21 24 drug drug NOUN ghmj-113 21 25 stability stability NOUN ghmj-113 21 26 . . PUNCT ghmj-113 22 1 in in ADP ghmj-113 22 2 addition addition NOUN ghmj-113 22 3 , , PUNCT ghmj-113 22 4 the the DET ghmj-113 22 5 nanoparticle nanoparticle NOUN ghmj-113 22 6 surface surface NOUN ghmj-113 22 7 can can AUX ghmj-113 22 8 be be AUX ghmj-113 22 9 further far ADV ghmj-113 22 10 modified modify VERB ghmj-113 22 11 for for ADP ghmj-113 22 12 specific specific ADJ ghmj-113 22 13 targeting targeting NOUN ghmj-113 22 14 purposes purpose NOUN ghmj-113 22 15 . . PUNCT ghmj-113 23 1 for for ADP ghmj-113 23 2 example example NOUN ghmj-113 23 3 , , PUNCT ghmj-113 23 4 nps nps PROPN ghmj-113 23 5 are be AUX ghmj-113 23 6 conjugated conjugate VERB ghmj-113 23 7 with with ADP ghmj-113 23 8 specific specific ADJ ghmj-113 23 9 antibodies antibody NOUN ghmj-113 23 10 against against ADP ghmj-113 23 11 cancer cancer NOUN ghmj-113 23 12 cells cell NOUN ghmj-113 23 13 and and CCONJ ghmj-113 23 14 used use VERB ghmj-113 23 15 to to PART ghmj-113 23 16 deliver deliver VERB ghmj-113 23 17 anti anti ADJ ghmj-113 23 18 - - ADJ ghmj-113 23 19 cancer cancer ADJ ghmj-113 23 20 drugs drug NOUN ghmj-113 23 21 for for ADP ghmj-113 23 22 therapeutic therapeutic ADJ ghmj-113 23 23 purpose purpose NOUN ghmj-113 24 1 [ [ X ghmj-113 24 2 5 5 NUM ghmj-113 24 3 ] ] PUNCT ghmj-113 24 4 . . PUNCT ghmj-113 25 1 poly poly ADJ ghmj-113 25 2 lactide lactide NOUN ghmj-113 25 3 - - PUNCT ghmj-113 25 4 co co NOUN ghmj-113 25 5 - - NOUN ghmj-113 25 6 glycolide glycolide ADJ ghmj-113 25 7 ( ( PUNCT ghmj-113 25 8 plga plga NOUN ghmj-113 25 9 ) ) PUNCT ghmj-113 25 10 is be AUX ghmj-113 25 11 one one NUM ghmj-113 25 12 of of ADP ghmj-113 25 13 the the DET ghmj-113 25 14 polymers polymer NOUN ghmj-113 25 15 that that PRON ghmj-113 25 16 can can AUX ghmj-113 25 17 form form VERB ghmj-113 25 18 nanoparticles nanoparticle NOUN ghmj-113 25 19 [ [ X ghmj-113 25 20 6 6 NUM ghmj-113 25 21 ] ] PUNCT ghmj-113 25 22 . . PUNCT ghmj-113 26 1 this this DET ghmj-113 26 2 linear linear ADJ ghmj-113 26 3 copolymer copolymer NOUN ghmj-113 26 4 can can AUX ghmj-113 26 5 be be AUX ghmj-113 26 6 hydrolyzed hydrolyze VERB ghmj-113 26 7 into into ADP ghmj-113 26 8 the the DET ghmj-113 26 9 two two NUM ghmj-113 26 10 non non ADJ ghmj-113 26 11 - - ADJ ghmj-113 26 12 toxic toxic ADJ ghmj-113 26 13 monomers monomer NOUN ghmj-113 26 14 : : PUNCT ghmj-113 26 15 lactic lactic ADJ ghmj-113 26 16 acid acid NOUN ghmj-113 26 17 and and CCONJ ghmj-113 26 18 glycolic glycolic NOUN ghmj-113 26 19 acid acid NOUN ghmj-113 27 1 [ [ X ghmj-113 27 2 7 7 NUM ghmj-113 27 3 ] ] PUNCT ghmj-113 27 4 , , PUNCT ghmj-113 27 5 therefore therefore ADV ghmj-113 27 6 , , PUNCT ghmj-113 27 7 plga plga NOUN ghmj-113 27 8 has have AUX ghmj-113 27 9 been be AUX ghmj-113 27 10 approved approve VERB ghmj-113 27 11 for for ADP ghmj-113 27 12 use use NOUN ghmj-113 27 13 in in ADP ghmj-113 27 14 biomedical biomedical ADJ ghmj-113 27 15 applications application NOUN ghmj-113 27 16 such such ADJ ghmj-113 27 17 as as ADP ghmj-113 27 18 drug drug NOUN ghmj-113 27 19 delivery delivery NOUN ghmj-113 27 20 by by ADP ghmj-113 27 21 the the DET ghmj-113 27 22 united united PROPN ghmj-113 27 23 states states PROPN ghmj-113 27 24 food food PROPN ghmj-113 27 25 and and CCONJ ghmj-113 27 26 drug drug PROPN ghmj-113 27 27 administration administration PROPN ghmj-113 27 28 ( ( PUNCT ghmj-113 27 29 fda fda PROPN ghmj-113 27 30 ) ) PUNCT ghmj-113 27 31 and and CCONJ ghmj-113 27 32 european european ADJ ghmj-113 27 33 medicine medicine PROPN ghmj-113 27 34 agency agency PROPN ghmj-113 27 35 ( ( PUNCT ghmj-113 27 36 ema ema PROPN ghmj-113 27 37 ) ) PUNCT ghmj-113 28 1 [ [ X ghmj-113 28 2 8 8 NUM ghmj-113 28 3 , , PUNCT ghmj-113 28 4 9 9 NUM ghmj-113 28 5 ] ] PUNCT ghmj-113 28 6 . . PUNCT ghmj-113 29 1 in in ADP ghmj-113 29 2 order order NOUN ghmj-113 29 3 to to PART ghmj-113 29 4 develop develop VERB ghmj-113 29 5 a a DET ghmj-113 29 6 successful successful ADJ ghmj-113 29 7 drug drug NOUN ghmj-113 29 8 carrier carrier NOUN ghmj-113 29 9 system system NOUN ghmj-113 29 10 , , PUNCT ghmj-113 29 11 the the DET ghmj-113 29 12 size size NOUN ghmj-113 29 13 of of ADP ghmj-113 29 14 nps nps PROPN ghmj-113 29 15 is be AUX ghmj-113 29 16 a a DET ghmj-113 29 17 key key ADJ ghmj-113 29 18 factor factor NOUN ghmj-113 29 19 especially especially ADV ghmj-113 29 20 in in ADP ghmj-113 29 21 cancer cancer NOUN ghmj-113 29 22 therapy therapy NOUN ghmj-113 29 23 [ [ X ghmj-113 29 24 1 1 NUM ghmj-113 29 25 , , PUNCT ghmj-113 29 26 2 2 NUM ghmj-113 29 27 ] ] PUNCT ghmj-113 29 28 . . PUNCT ghmj-113 30 1 several several ADJ ghmj-113 30 2 reports report NOUN ghmj-113 30 3 show show VERB ghmj-113 30 4 that that PRON ghmj-113 30 5 size size NOUN ghmj-113 30 6 and and CCONJ ghmj-113 30 7 size size NOUN ghmj-113 30 8 distribution distribution NOUN ghmj-113 30 9 of of ADP ghmj-113 30 10 nps nps PROPN ghmj-113 30 11 play play VERB ghmj-113 30 12 important important ADJ ghmj-113 30 13 role role NOUN ghmj-113 30 14 in in ADP ghmj-113 30 15 term term NOUN ghmj-113 30 16 of of ADP ghmj-113 30 17 in in ADP ghmj-113 30 18 vivo vivo ADJ ghmj-113 30 19 biodistribution biodistribution NOUN ghmj-113 30 20 , , PUNCT ghmj-113 30 21 biological biological ADJ ghmj-113 30 22 fate fate NOUN ghmj-113 30 23 and and CCONJ ghmj-113 30 24 toxicity toxicity NOUN ghmj-113 30 25 [ [ X ghmj-113 30 26 10 10 NUM ghmj-113 30 27 ] ] PUNCT ghmj-113 30 28 . . PUNCT ghmj-113 31 1 smaller small ADJ ghmj-113 31 2 particles particle NOUN ghmj-113 31 3 have have VERB ghmj-113 31 4 relatively relatively ADV ghmj-113 31 5 higher high ADJ ghmj-113 31 6 uptake uptake ADJ ghmj-113 31 7 efficiency efficiency NOUN ghmj-113 31 8 to to ADP ghmj-113 31 9 the the DET ghmj-113 31 10 targeted target VERB ghmj-113 31 11 cells cell NOUN ghmj-113 31 12 compared compare VERB ghmj-113 31 13 to to ADP ghmj-113 31 14 larger large ADJ ghmj-113 31 15 particles particle NOUN ghmj-113 31 16 but but CCONJ ghmj-113 31 17 have have VERB ghmj-113 31 18 smaller small ADJ ghmj-113 31 19 inner inner ADJ ghmj-113 31 20 space space NOUN ghmj-113 31 21 for for ADP ghmj-113 31 22 drug drug NOUN ghmj-113 31 23 entrapment entrapment ADJ ghmj-113 31 24 [ [ PUNCT ghmj-113 31 25 11 11 NUM ghmj-113 31 26 ] ] PUNCT ghmj-113 31 27 . . PUNCT ghmj-113 32 1 in in ADP ghmj-113 32 2 addition addition NOUN ghmj-113 32 3 , , PUNCT ghmj-113 32 4 the the DET ghmj-113 32 5 drugs drug NOUN ghmj-113 32 6 in in ADP ghmj-113 32 7 the the DET ghmj-113 32 8 small small PROPN ghmj-113 32 9 nps nps PROPN ghmj-113 32 10 are be AUX ghmj-113 32 11 at at ADP ghmj-113 32 12 or or CCONJ ghmj-113 32 13 near near ADP ghmj-113 32 14 the the DET ghmj-113 32 15 particle particle NOUN ghmj-113 32 16 surface surface NOUN ghmj-113 32 17 , , PUNCT ghmj-113 32 18 leading lead VERB ghmj-113 32 19 to to ADP ghmj-113 32 20 faster fast ADJ ghmj-113 32 21 drug drug NOUN ghmj-113 32 22 release release NOUN ghmj-113 32 23 compared compare VERB ghmj-113 32 24 to to ADP ghmj-113 32 25 large large ADJ ghmj-113 32 26 particle particle NOUN ghmj-113 32 27 size size NOUN ghmj-113 32 28 [ [ X ghmj-113 32 29 12 12 NUM ghmj-113 32 30 ] ] PUNCT ghmj-113 32 31 . . PUNCT ghmj-113 33 1 this this DET ghmj-113 33 2 faster fast ADJ ghmj-113 33 3 release release NOUN ghmj-113 33 4 rate rate NOUN ghmj-113 33 5 in in ADP ghmj-113 33 6 smaller small ADJ ghmj-113 33 7 nanoparticles nanoparticle NOUN ghmj-113 33 8 was be AUX ghmj-113 33 9 also also ADV ghmj-113 33 10 observed observe VERB ghmj-113 33 11 in in ADP ghmj-113 33 12 a a DET ghmj-113 33 13 bovine bovine NOUN ghmj-113 33 14 serum serum NOUN ghmj-113 33 15 albumin albumin ADJ ghmj-113 33 16 protein protein NOUN ghmj-113 33 17 release release NOUN ghmj-113 33 18 model model NOUN ghmj-113 33 19 [ [ X ghmj-113 33 20 13 13 NUM ghmj-113 33 21 ] ] PUNCT ghmj-113 33 22 . . PUNCT ghmj-113 34 1 therefore therefore ADV ghmj-113 34 2 , , PUNCT ghmj-113 34 3 the the DET ghmj-113 34 4 small small ADJ ghmj-113 34 5 nps nps PROPN ghmj-113 34 6 would would AUX ghmj-113 34 7 be be AUX ghmj-113 34 8 suitable suitable ADJ ghmj-113 34 9 for for ADP ghmj-113 34 10 drug drug NOUN ghmj-113 34 11 delivery delivery NOUN ghmj-113 34 12 that that PRON ghmj-113 34 13 requires require VERB ghmj-113 34 14 fast fast ADJ ghmj-113 34 15 release release NOUN ghmj-113 34 16 rate rate NOUN ghmj-113 34 17 whereas whereas SCONJ ghmj-113 34 18 the the DET ghmj-113 34 19 large large ADJ ghmj-113 34 20 particles particle NOUN ghmj-113 34 21 would would AUX ghmj-113 34 22 be be AUX ghmj-113 34 23 appropriate appropriate ADJ ghmj-113 34 24 for for ADP ghmj-113 34 25 drug drug NOUN ghmj-113 34 26 that that PRON ghmj-113 34 27 requires require VERB ghmj-113 34 28 slow slow ADJ ghmj-113 34 29 release release NOUN ghmj-113 34 30 rate rate NOUN ghmj-113 34 31 . . PUNCT ghmj-113 35 1 due due ADP ghmj-113 35 2 to to ADP ghmj-113 35 3 the the DET ghmj-113 35 4 importance importance NOUN ghmj-113 35 5 of of ADP ghmj-113 35 6 drug drug NOUN ghmj-113 35 7 carrier carrier NOUN ghmj-113 35 8 size size NOUN ghmj-113 35 9 , , PUNCT ghmj-113 35 10 the the DET ghmj-113 35 11 development development NOUN ghmj-113 35 12 of of ADP ghmj-113 35 13 synthesis synthesis NOUN ghmj-113 35 14 methods method NOUN ghmj-113 35 15 for for ADP ghmj-113 35 16 preparation preparation NOUN ghmj-113 35 17 of of ADP ghmj-113 35 18 different different ADJ ghmj-113 35 19 np np NOUN ghmj-113 35 20 sizes size NOUN ghmj-113 35 21 is be AUX ghmj-113 35 22 important important ADJ ghmj-113 35 23 to to PART ghmj-113 35 24 provide provide VERB ghmj-113 35 25 the the DET ghmj-113 35 26 most most ADV ghmj-113 35 27 optimal optimal ADJ ghmj-113 35 28 size size NOUN ghmj-113 35 29 and and CCONJ ghmj-113 35 30 property property NOUN ghmj-113 35 31 to to ADP ghmj-113 35 32 each each DET ghmj-113 35 33 specific specific ADJ ghmj-113 35 34 drug drug NOUN ghmj-113 35 35 delivery delivery NOUN ghmj-113 35 36 requirement requirement NOUN ghmj-113 35 37 [ [ X ghmj-113 35 38 14 14 NUM ghmj-113 35 39 ] ] PUNCT ghmj-113 35 40 . . PUNCT ghmj-113 36 1 this this DET ghmj-113 36 2 study study NOUN ghmj-113 36 3 focuses focus VERB ghmj-113 36 4 on on ADP ghmj-113 36 5 development development NOUN ghmj-113 36 6 of of ADP ghmj-113 36 7 tunable tunable ADJ ghmj-113 36 8 size size NOUN ghmj-113 36 9 of of ADP ghmj-113 36 10 plga plga NOUN ghmj-113 36 11 nps nps PROPN ghmj-113 36 12 . . PROPN ghmj-113 37 1 four four NUM ghmj-113 37 2 different different ADJ ghmj-113 37 3 parameters parameter NOUN ghmj-113 37 4 that that PRON ghmj-113 37 5 might might AUX ghmj-113 37 6 affect affect VERB ghmj-113 37 7 particle particle NOUN ghmj-113 37 8 sizes size NOUN ghmj-113 37 9 ( ( PUNCT ghmj-113 37 10 molecular molecular ADJ ghmj-113 37 11 weight weight NOUN ghmj-113 37 12 of of ADP ghmj-113 37 13 plga plga NOUN ghmj-113 37 14 polymer polymer NOUN ghmj-113 37 15 , , PUNCT ghmj-113 37 16 emulsifier emulsifier NOUN ghmj-113 37 17 concentrations concentration NOUN ghmj-113 37 18 , , PUNCT ghmj-113 37 19 type type NOUN ghmj-113 37 20 of of ADP ghmj-113 37 21 organic organic ADJ ghmj-113 37 22 solvent solvent NOUN ghmj-113 37 23 and and CCONJ ghmj-113 37 24 power power NOUN ghmj-113 37 25 of of ADP ghmj-113 37 26 ultrasonication ultrasonication NOUN ghmj-113 37 27 ) ) PUNCT ghmj-113 37 28 are be AUX ghmj-113 37 29 investigated investigate VERB ghmj-113 37 30 . . PUNCT ghmj-113 38 1 the the DET ghmj-113 38 2 overall overall ADJ ghmj-113 38 3 scheme scheme NOUN ghmj-113 38 4 of of ADP ghmj-113 38 5 plga plga NOUN ghmj-113 38 6 nps nps PROPN ghmj-113 38 7 synthesis synthesis NOUN ghmj-113 38 8 is be AUX ghmj-113 38 9 shown show VERB ghmj-113 38 10 in in ADP ghmj-113 38 11 figure figure NOUN ghmj-113 38 12 1 1 NUM ghmj-113 38 13 . . PUNCT ghmj-113 38 14 figure figure NOUN ghmj-113 38 15 1 1 NUM ghmj-113 38 16 . . PUNCT ghmj-113 38 17 schematic schematic ADJ ghmj-113 38 18 representation representation NOUN ghmj-113 38 19 of of ADP ghmj-113 38 20 general general ADJ ghmj-113 38 21 procedure procedure NOUN ghmj-113 38 22 of of ADP ghmj-113 38 23 preparation preparation NOUN ghmj-113 38 24 of of ADP ghmj-113 38 25 plga plga NOUN ghmj-113 38 26 nanoparticle nanoparticle NOUN ghmj-113 38 27 by by ADP ghmj-113 38 28 emulsion emulsion NOUN ghmj-113 38 29 solvent solvent NOUN ghmj-113 38 30 evaporation evaporation NOUN ghmj-113 38 31 method method NOUN ghmj-113 38 32 . . PUNCT ghmj-113 39 1 33 33 NUM ghmj-113 39 2                                                                   SPACE ghmj-113 39 3 global global ADJ ghmj-113 39 4     SPACE ghmj-113 39 5 health health NOUN ghmj-113 39 6     SPACE ghmj-113 39 7 management management NOUN ghmj-113 39 8     SPACE ghmj-113 39 9 journal journal NOUN ghmj-113 39 10 , , PUNCT ghmj-113 39 11     SPACE ghmj-113 39 12 2017 2017 NUM ghmj-113 39 13 , , PUNCT ghmj-113 39 14     SPACE ghmj-113 39 15 vol vol NOUN ghmj-113 39 16 . . PUNCT ghmj-113 39 17     SPACE ghmj-113 39 18 1 1 NUM ghmj-113 39 19 , , PUNCT ghmj-113 39 20     SPACE ghmj-113 39 21 no no INTJ ghmj-113 39 22 . . PUNCT ghmj-113 39 23     SPACE ghmj-113 39 24 2 2 NUM ghmj-113 39 25                 SPACE ghmj-113 39 26 methods method NOUN ghmj-113 39 27 materials material NOUN ghmj-113 39 28 plga plga VERB ghmj-113 39 29 nps nps PROPN ghmj-113 39 30 were be AUX ghmj-113 39 31 prepared prepare VERB ghmj-113 39 32 by by ADP ghmj-113 39 33 a a DET ghmj-113 39 34 modification modification NOUN ghmj-113 39 35 of of ADP ghmj-113 39 36 emulsion emulsion NOUN ghmj-113 39 37 solvent solvent NOUN ghmj-113 39 38 evaporation evaporation NOUN ghmj-113 39 39 method method NOUN ghmj-113 39 40 as as SCONJ ghmj-113 39 41 previously previously ADV ghmj-113 39 42 described describe VERB ghmj-113 39 43 [ [ PUNCT ghmj-113 39 44 15,16 15,16 NUM ghmj-113 39 45 ] ] PUNCT ghmj-113 39 46 . . PUNCT ghmj-113 40 1 four four NUM ghmj-113 40 2 parameters parameter NOUN ghmj-113 40 3 were be AUX ghmj-113 40 4 investigated investigate VERB ghmj-113 40 5 : : PUNCT ghmj-113 40 6 ( ( PUNCT ghmj-113 40 7 i i NOUN ghmj-113 40 8 ) ) PUNCT ghmj-113 40 9 size size NOUN ghmj-113 40 10 of of ADP ghmj-113 40 11 plga plga NOUN ghmj-113 40 12 polymer polymer NOUN ghmj-113 40 13 ( ( PUNCT ghmj-113 40 14 60,000 60,000 NUM ghmj-113 40 15 g g NOUN ghmj-113 40 16 / / SYM ghmj-113 40 17 mol mol NOUN ghmj-113 40 18 and and CCONJ ghmj-113 40 19 80,000 80,000 NUM ghmj-113 40 20 g g NOUN ghmj-113 40 21 / / SYM ghmj-113 40 22 mol mol NOUN ghmj-113 40 23 ) ) PUNCT ghmj-113 40 24 , , PUNCT ghmj-113 40 25 ( ( PUNCT ghmj-113 40 26 ii ii NOUN ghmj-113 40 27 ) ) PUNCT ghmj-113 40 28 concentration concentration NOUN ghmj-113 40 29 of of ADP ghmj-113 40 30 pva pva NOUN ghmj-113 40 31 that that PRON ghmj-113 40 32 acts act VERB ghmj-113 40 33 as as ADP ghmj-113 40 34 emulsifier emulsifier NOUN ghmj-113 40 35 ( ( PUNCT ghmj-113 40 36 1 1 NUM ghmj-113 40 37 - - SYM ghmj-113 40 38 10 10 NUM ghmj-113 40 39 % % NOUN ghmj-113 40 40 ( ( PUNCT ghmj-113 40 41 w w NOUN ghmj-113 40 42 / / SYM ghmj-113 40 43 v v NOUN ghmj-113 40 44 ) ) PUNCT ghmj-113 40 45 ) ) PUNCT ghmj-113 40 46 , , PUNCT ghmj-113 40 47 ( ( PUNCT ghmj-113 40 48 iii iii NOUN ghmj-113 40 49 ) ) PUNCT ghmj-113 40 50 type type NOUN ghmj-113 40 51 of of ADP ghmj-113 40 52 organic organic ADJ ghmj-113 40 53 solvent solvent NOUN ghmj-113 40 54 ( ( PUNCT ghmj-113 40 55 etoac etoac ADJ ghmj-113 40 56 and and CCONJ ghmj-113 40 57 dcm dcm PROPN ghmj-113 40 58 ) ) PUNCT ghmj-113 40 59 and and CCONJ ghmj-113 40 60 ( ( PUNCT ghmj-113 40 61 iv iv X ghmj-113 40 62 ) ) PUNCT ghmj-113 40 63 power power NOUN ghmj-113 40 64 of of ADP ghmj-113 40 65 ultrasonication ultrasonication NOUN ghmj-113 40 66 ( ( PUNCT ghmj-113 40 67 10 10 NUM ghmj-113 40 68 % % NOUN ghmj-113 40 69 , , PUNCT ghmj-113 40 70 35 35 NUM ghmj-113 40 71 % % NOUN ghmj-113 40 72 and and CCONJ ghmj-113 40 73 38 38 NUM ghmj-113 40 74 % % NOUN ghmj-113 40 75 amplitude amplitude NOUN ghmj-113 40 76 ) ) PUNCT ghmj-113 40 77 . . PUNCT ghmj-113 41 1 preparation preparation NOUN ghmj-113 41 2 of of ADP ghmj-113 41 3 plga plga NOUN ghmj-113 41 4 nps nps PROPN ghmj-113 41 5 plga plga NOUN ghmj-113 41 6 nps nps PROPN ghmj-113 41 7 were be AUX ghmj-113 41 8 prepared prepare VERB ghmj-113 41 9 by by ADP ghmj-113 41 10 a a DET ghmj-113 41 11 modification modification NOUN ghmj-113 41 12 of of ADP ghmj-113 41 13 emulsion emulsion NOUN ghmj-113 41 14 solvent solvent NOUN ghmj-113 41 15 evaporation evaporation NOUN ghmj-113 41 16 method method NOUN ghmj-113 41 17 as as SCONJ ghmj-113 41 18 previously previously ADV ghmj-113 41 19 described describe VERB ghmj-113 41 20 [ [ X ghmj-113 41 21 15 15 NUM ghmj-113 41 22 , , PUNCT ghmj-113 41 23 16 16 NUM ghmj-113 41 24 ] ] PUNCT ghmj-113 41 25 . . PUNCT ghmj-113 42 1 four four NUM ghmj-113 42 2 parameters parameter NOUN ghmj-113 42 3 were be AUX ghmj-113 42 4 investigated investigate VERB ghmj-113 42 5 : : PUNCT ghmj-113 42 6 ( ( PUNCT ghmj-113 42 7 i i NOUN ghmj-113 42 8 ) ) PUNCT ghmj-113 42 9 size size NOUN ghmj-113 42 10 of of ADP ghmj-113 42 11 plga plga NOUN ghmj-113 42 12 polymer polymer NOUN ghmj-113 42 13 ( ( PUNCT ghmj-113 42 14 60,000 60,000 NUM ghmj-113 42 15 g g NOUN ghmj-113 42 16 / / SYM ghmj-113 42 17 mol mol NOUN ghmj-113 42 18 and and CCONJ ghmj-113 42 19 80,000 80,000 NUM ghmj-113 42 20 g g NOUN ghmj-113 42 21 / / SYM ghmj-113 42 22 mol mol NOUN ghmj-113 42 23 ) ) PUNCT ghmj-113 42 24 , , PUNCT ghmj-113 42 25 ( ( PUNCT ghmj-113 42 26 ii ii NOUN ghmj-113 42 27 ) ) PUNCT ghmj-113 42 28 concentration concentration NOUN ghmj-113 42 29 of of ADP ghmj-113 42 30 pva pva NOUN ghmj-113 42 31 that that PRON ghmj-113 42 32 acts act VERB ghmj-113 42 33 as as ADP ghmj-113 42 34 emulsifier emulsifier NOUN ghmj-113 42 35 ( ( PUNCT ghmj-113 42 36 1 1 NUM ghmj-113 42 37 - - SYM ghmj-113 42 38 10 10 NUM ghmj-113 42 39 % % NOUN ghmj-113 42 40 ( ( PUNCT ghmj-113 42 41 w w NOUN ghmj-113 42 42 / / SYM ghmj-113 42 43 v v NOUN ghmj-113 42 44 ) ) PUNCT ghmj-113 42 45 ) ) PUNCT ghmj-113 42 46 , , PUNCT ghmj-113 42 47 ( ( PUNCT ghmj-113 42 48 iii iii NOUN ghmj-113 42 49 ) ) PUNCT ghmj-113 42 50 type type NOUN ghmj-113 42 51 of of ADP ghmj-113 42 52 organic organic ADJ ghmj-113 42 53 solvent solvent NOUN ghmj-113 42 54 ( ( PUNCT ghmj-113 42 55 etoac etoac ADJ ghmj-113 42 56 and and CCONJ ghmj-113 42 57 dcm dcm PROPN ghmj-113 42 58 ) ) PUNCT ghmj-113 42 59 and and CCONJ ghmj-113 42 60 ( ( PUNCT ghmj-113 42 61 iv iv X ghmj-113 42 62 ) ) PUNCT ghmj-113 42 63 power power NOUN ghmj-113 42 64 of of ADP ghmj-113 42 65 ultrasonication ultrasonication NOUN ghmj-113 42 66 ( ( PUNCT ghmj-113 42 67 10 10 NUM ghmj-113 42 68 % % NOUN ghmj-113 42 69 , , PUNCT ghmj-113 42 70 35 35 NUM ghmj-113 42 71 % % NOUN ghmj-113 42 72 and and CCONJ ghmj-113 42 73 38 38 NUM ghmj-113 42 74 % % NOUN ghmj-113 42 75 amplitude amplitude NOUN ghmj-113 42 76 ) ) PUNCT ghmj-113 42 77 . . PUNCT ghmj-113 43 1 preparation preparation NOUN ghmj-113 43 2 of of ADP ghmj-113 43 3 plga plga NOUN ghmj-113 43 4 nps nps PROPN ghmj-113 43 5 using use VERB ghmj-113 43 6 different different ADJ ghmj-113 43 7 molecular molecular ADJ ghmj-113 43 8 weight weight NOUN ghmj-113 43 9 of of ADP ghmj-113 43 10 plga plga NOUN ghmj-113 43 11 a a DET ghmj-113 43 12 total total NOUN ghmj-113 43 13 of of ADP ghmj-113 43 14 50 50 NUM ghmj-113 43 15 mg mg NOUN ghmj-113 43 16 of of ADP ghmj-113 43 17 two two NUM ghmj-113 43 18 different different ADJ ghmj-113 43 19 mw mw NOUN ghmj-113 43 20 of of ADP ghmj-113 43 21 plga plga NOUN ghmj-113 43 22 polymer polymer NOUN ghmj-113 43 23 ( ( PUNCT ghmj-113 43 24 60,000 60,000 NUM ghmj-113 43 25 and and CCONJ ghmj-113 43 26 80,000 80,000 NUM ghmj-113 43 27 g g NOUN ghmj-113 43 28 / / SYM ghmj-113 43 29 mol mol NOUN ghmj-113 43 30 ) ) PUNCT ghmj-113 43 31 was be AUX ghmj-113 43 32 dissolved dissolve VERB ghmj-113 43 33 in in ADP ghmj-113 43 34 0.5 0.5 NUM ghmj-113 43 35 ml ml NOUN ghmj-113 43 36 etoac etoac ADJ ghmj-113 43 37 . . PUNCT ghmj-113 44 1 the the DET ghmj-113 44 2 plga plga NOUN ghmj-113 44 3 solution solution NOUN ghmj-113 44 4 was be AUX ghmj-113 44 5 added add VERB ghmj-113 44 6 dropwise dropwise NOUN ghmj-113 44 7 to to ADP ghmj-113 44 8 2 2 NUM ghmj-113 44 9 ml ml NOUN ghmj-113 44 10 of of ADP ghmj-113 44 11 pva pva NOUN ghmj-113 44 12 dissolved dissolve VERB ghmj-113 44 13 in in ADP ghmj-113 44 14 water water NOUN ghmj-113 44 15 under under ADP ghmj-113 44 16 vortex vortex NOUN ghmj-113 44 17 . . PUNCT ghmj-113 45 1 afterwards afterwards ADV ghmj-113 45 2 , , PUNCT ghmj-113 45 3 the the DET ghmj-113 45 4 emulsion emulsion NOUN ghmj-113 45 5 solution solution NOUN ghmj-113 45 6 was be AUX ghmj-113 45 7 treated treat VERB ghmj-113 45 8 with with ADP ghmj-113 45 9 3 3 NUM ghmj-113 45 10 cycles cycle NOUN ghmj-113 45 11 of of ADP ghmj-113 45 12 30 30 NUM ghmj-113 45 13 seconds second NOUN ghmj-113 45 14 pulse pulse NOUN ghmj-113 45 15 ( ( PUNCT ghmj-113 45 16 38 38 NUM ghmj-113 45 17 % % NOUN ghmj-113 45 18 amplitude amplitude NOUN ghmj-113 45 19 ) ) PUNCT ghmj-113 45 20 . . PUNCT ghmj-113 46 1 at at ADP ghmj-113 46 2 the the DET ghmj-113 46 3 end end NOUN ghmj-113 46 4 of of ADP ghmj-113 46 5 the the DET ghmj-113 46 6 cycles cycle NOUN ghmj-113 46 7 , , PUNCT ghmj-113 46 8 the the DET ghmj-113 46 9 solution solution NOUN ghmj-113 46 10 was be AUX ghmj-113 46 11 quickly quickly ADV ghmj-113 46 12 added add VERB ghmj-113 46 13 into into ADP ghmj-113 46 14 25 25 NUM ghmj-113 46 15 ml ml NOUN ghmj-113 46 16 of of ADP ghmj-113 46 17 0.3 0.3 NUM ghmj-113 46 18 % % NOUN ghmj-113 46 19 pva pva NOUN ghmj-113 46 20 under under ADP ghmj-113 46 21 stirring stir VERB ghmj-113 46 22 for for ADP ghmj-113 46 23 4 4 NUM ghmj-113 46 24 hours hour NOUN ghmj-113 46 25 to to PART ghmj-113 46 26 evaporate evaporate VERB ghmj-113 46 27 the the DET ghmj-113 46 28 organic organic ADJ ghmj-113 46 29 solvent solvent NOUN ghmj-113 46 30 . . PUNCT ghmj-113 47 1 the the DET ghmj-113 47 2 plga plga NOUN ghmj-113 47 3 nanoparticles nanoparticle NOUN ghmj-113 47 4 were be AUX ghmj-113 47 5 collected collect VERB ghmj-113 47 6 by by ADP ghmj-113 47 7 centrifugation centrifugation NOUN ghmj-113 47 8 at at ADP ghmj-113 47 9 15,000 15,000 NUM ghmj-113 47 10 rpm rpm NOUN ghmj-113 47 11 for for ADP ghmj-113 47 12 15 15 NUM ghmj-113 47 13 minutes minute NOUN ghmj-113 47 14 . . PUNCT ghmj-113 48 1 after after ADP ghmj-113 48 2 that that PRON ghmj-113 48 3 , , PUNCT ghmj-113 48 4 plga plga VERB ghmj-113 48 5 nanoparticles nanoparticle NOUN ghmj-113 48 6 were be AUX ghmj-113 48 7 washed wash VERB ghmj-113 48 8 for for ADP ghmj-113 48 9 three three NUM ghmj-113 48 10 times time NOUN ghmj-113 48 11 with with ADP ghmj-113 48 12 deionized deionize VERB ghmj-113 48 13 water water NOUN ghmj-113 48 14 and and CCONJ ghmj-113 48 15 followed follow VERB ghmj-113 48 16 by by ADP ghmj-113 48 17 lyophilization lyophilization NOUN ghmj-113 48 18 . . PUNCT ghmj-113 49 1 preparation preparation NOUN ghmj-113 49 2 of of ADP ghmj-113 49 3 plga plga NOUN ghmj-113 49 4 nps nps PROPN ghmj-113 49 5 using use VERB ghmj-113 49 6 different different ADJ ghmj-113 49 7 emulsifier emulsifier NOUN ghmj-113 49 8 concentrations concentration NOUN ghmj-113 49 9 to to PART ghmj-113 49 10 study study VERB ghmj-113 49 11 the the DET ghmj-113 49 12 effect effect NOUN ghmj-113 49 13 of of ADP ghmj-113 49 14 emulsifier emulsifier NOUN ghmj-113 49 15 concentrations concentration NOUN ghmj-113 49 16 , , PUNCT ghmj-113 49 17 50 50 NUM ghmj-113 49 18 mg mg NOUN ghmj-113 49 19 plga plga NOUN ghmj-113 49 20 polymer polymer NOUN ghmj-113 49 21 ( ( PUNCT ghmj-113 49 22 60,000 60,000 NUM ghmj-113 49 23 g g NOUN ghmj-113 49 24 / / SYM ghmj-113 49 25 mol mol NOUN ghmj-113 49 26 ) ) PUNCT ghmj-113 49 27 was be AUX ghmj-113 49 28 dissolved dissolve VERB ghmj-113 49 29 in in ADP ghmj-113 49 30 0.5 0.5 NUM ghmj-113 49 31 ml ml NOUN ghmj-113 49 32 etoac etoac ADJ ghmj-113 49 33 . . PUNCT ghmj-113 50 1 the the DET ghmj-113 50 2 plga plga NOUN ghmj-113 50 3 solution solution NOUN ghmj-113 50 4 was be AUX ghmj-113 50 5 added add VERB ghmj-113 50 6 dropwise dropwise NOUN ghmj-113 50 7 to to ADP ghmj-113 50 8 2 2 NUM ghmj-113 50 9 ml ml NOUN ghmj-113 50 10 of of ADP ghmj-113 50 11 different different ADJ ghmj-113 50 12 pva pva NOUN ghmj-113 50 13 concentrations concentration NOUN ghmj-113 50 14 dissolved dissolve VERB ghmj-113 50 15 in in ADP ghmj-113 50 16 water water NOUN ghmj-113 50 17 ( ( PUNCT ghmj-113 50 18 1 1 NUM ghmj-113 50 19 % % NOUN ghmj-113 50 20 , , PUNCT ghmj-113 50 21 5 5 NUM ghmj-113 50 22 % % NOUN ghmj-113 50 23 and and CCONJ ghmj-113 50 24 10 10 NUM ghmj-113 50 25 % % NOUN ghmj-113 50 26 ( ( PUNCT ghmj-113 50 27 w w NOUN ghmj-113 50 28 / / SYM ghmj-113 50 29 v v NOUN ghmj-113 50 30 ) ) PUNCT ghmj-113 50 31 ) ) PUNCT ghmj-113 50 32 under under ADP ghmj-113 50 33 vortex vortex NOUN ghmj-113 50 34 . . PUNCT ghmj-113 51 1 the the DET ghmj-113 51 2 mixture mixture NOUN ghmj-113 51 3 was be AUX ghmj-113 51 4 emulsified emulsify VERB ghmj-113 51 5 , , PUNCT ghmj-113 51 6 collected collect VERB ghmj-113 51 7 and and CCONJ ghmj-113 51 8 stored store VERB ghmj-113 51 9 using use VERB ghmj-113 51 10 the the DET ghmj-113 51 11 same same ADJ ghmj-113 51 12 procedure procedure NOUN ghmj-113 51 13 as as SCONJ ghmj-113 51 14 described describe VERB ghmj-113 51 15 above above ADV ghmj-113 51 16 . . PUNCT ghmj-113 52 1 preparation preparation NOUN ghmj-113 52 2 of of ADP ghmj-113 52 3 plga plga NOUN ghmj-113 52 4 nps nps PROPN ghmj-113 52 5 using use VERB ghmj-113 52 6 different different ADJ ghmj-113 52 7 organic organic ADJ ghmj-113 52 8 solvent solvent ADJ ghmj-113 52 9 types type NOUN ghmj-113 52 10 to to PART ghmj-113 52 11 study study VERB ghmj-113 52 12 the the DET ghmj-113 52 13 effect effect NOUN ghmj-113 52 14 of of ADP ghmj-113 52 15 organic organic ADJ ghmj-113 52 16 solvent solvent NOUN ghmj-113 52 17 type type NOUN ghmj-113 52 18 , , PUNCT ghmj-113 52 19 50 50 NUM ghmj-113 52 20 mg mg NOUN ghmj-113 52 21 plga plga NOUN ghmj-113 52 22 polymer polymer NOUN ghmj-113 52 23 ( ( PUNCT ghmj-113 52 24 60,000 60,000 NUM ghmj-113 52 25 g g NOUN ghmj-113 52 26 / / SYM ghmj-113 52 27 mol mol NOUN ghmj-113 52 28 ) ) PUNCT ghmj-113 52 29 was be AUX ghmj-113 52 30 dissolved dissolve VERB ghmj-113 52 31 in in ADP ghmj-113 52 32 0.5 0.5 NUM ghmj-113 52 33 ml ml NOUN ghmj-113 52 34 of of ADP ghmj-113 52 35 different different ADJ ghmj-113 52 36 organic organic ADJ ghmj-113 52 37 solvents solvent NOUN ghmj-113 52 38 ( ( PUNCT ghmj-113 52 39 etoac etoac ADJ ghmj-113 52 40 or or CCONJ ghmj-113 52 41 dcm dcm NOUN ghmj-113 52 42 ) ) PUNCT ghmj-113 52 43 . . PUNCT ghmj-113 53 1 the the DET ghmj-113 53 2 plga plga NOUN ghmj-113 53 3 solution solution NOUN ghmj-113 53 4 was be AUX ghmj-113 53 5 added add VERB ghmj-113 53 6 dropwise dropwise NOUN ghmj-113 53 7 to to ADP ghmj-113 53 8 2 2 NUM ghmj-113 53 9 ml ml NOUN ghmj-113 53 10 of of ADP ghmj-113 53 11 5 5 NUM ghmj-113 53 12 % % NOUN ghmj-113 53 13 ( ( PUNCT ghmj-113 53 14 w w NOUN ghmj-113 53 15 / / SYM ghmj-113 53 16 v v NOUN ghmj-113 53 17 ) ) PUNCT ghmj-113 53 18 pva pva NOUN ghmj-113 53 19 dissolved dissolve VERB ghmj-113 53 20 in in ADP ghmj-113 53 21 water water NOUN ghmj-113 53 22 under under ADP ghmj-113 53 23 vortex vortex NOUN ghmj-113 53 24 . . PUNCT ghmj-113 54 1 the the DET ghmj-113 54 2 mixture mixture NOUN ghmj-113 54 3 was be AUX ghmj-113 54 4 emulsified emulsify VERB ghmj-113 54 5 , , PUNCT ghmj-113 54 6 collected collect VERB ghmj-113 54 7 and and CCONJ ghmj-113 54 8 stored store VERB ghmj-113 54 9 using use VERB ghmj-113 54 10 the the DET ghmj-113 54 11 same same ADJ ghmj-113 54 12 procedure procedure NOUN ghmj-113 54 13 as as SCONJ ghmj-113 54 14 described describe VERB ghmj-113 54 15 above above ADV ghmj-113 54 16 . . PUNCT ghmj-113 55 1 preparation preparation NOUN ghmj-113 55 2 of of ADP ghmj-113 55 3 plga plga NOUN ghmj-113 55 4 nps nps PROPN ghmj-113 55 5 using use VERB ghmj-113 55 6 different different ADJ ghmj-113 55 7 power power NOUN ghmj-113 55 8 of of ADP ghmj-113 55 9 ultrasonication ultrasonication NOUN ghmj-113 55 10 to to PART ghmj-113 55 11 study study VERB ghmj-113 55 12 the the DET ghmj-113 55 13 last last ADJ ghmj-113 55 14 parameter parameter NOUN ghmj-113 55 15 : : PUNCT ghmj-113 55 16 the the DET ghmj-113 55 17 power power NOUN ghmj-113 55 18 of of ADP ghmj-113 55 19 ultrasonication ultrasonication NOUN ghmj-113 55 20 , , PUNCT ghmj-113 55 21 50 50 NUM ghmj-113 55 22 mg mg NOUN ghmj-113 55 23 plga plga NOUN ghmj-113 55 24 polymer polymer NOUN ghmj-113 55 25 ( ( PUNCT ghmj-113 55 26 60,000 60,000 NUM ghmj-113 55 27 g g NOUN ghmj-113 55 28 / / SYM ghmj-113 55 29 mol mol NOUN ghmj-113 55 30 ) ) PUNCT ghmj-113 55 31 was be AUX ghmj-113 55 32 dissolved dissolve VERB ghmj-113 55 33 in in ADP ghmj-113 55 34 0.5 0.5 NUM ghmj-113 55 35 ml ml NOUN ghmj-113 55 36 etoac etoac ADJ ghmj-113 55 37 . . PUNCT ghmj-113 56 1 the the DET ghmj-113 56 2 plga plga NOUN ghmj-113 56 3 solution solution NOUN ghmj-113 56 4 was be AUX ghmj-113 56 5 added add VERB ghmj-113 56 6 dropwise dropwise NOUN ghmj-113 56 7 to to ADP ghmj-113 56 8 2 2 NUM ghmj-113 56 9 ml ml NOUN ghmj-113 56 10 of of ADP ghmj-113 56 11 5 5 NUM ghmj-113 56 12 % % NOUN ghmj-113 56 13 ( ( PUNCT ghmj-113 56 14 w w NOUN ghmj-113 56 15 / / SYM ghmj-113 56 16 v v NOUN ghmj-113 56 17 ) ) PUNCT ghmj-113 56 18 pva pva NOUN ghmj-113 56 19 dissolved dissolve VERB ghmj-113 56 20 in in ADP ghmj-113 56 21 water water NOUN ghmj-113 56 22 under under ADP ghmj-113 56 23 vortex vortex NOUN ghmj-113 56 24 . . PUNCT ghmj-113 57 1 the the DET ghmj-113 57 2 mixed mixed ADJ ghmj-113 57 3 solution solution NOUN ghmj-113 57 4 was be AUX ghmj-113 57 5 subsequently subsequently ADV ghmj-113 57 6 emulsified emulsify VERB ghmj-113 57 7 by by ADP ghmj-113 57 8 sonication sonication NOUN ghmj-113 57 9 with with ADP ghmj-113 57 10 3 3 NUM ghmj-113 57 11 cycles cycle NOUN ghmj-113 57 12 of of ADP ghmj-113 57 13 30 30 NUM ghmj-113 57 14 - - PUNCT ghmj-113 57 15 second second NOUN ghmj-113 57 16 pulses pulse NOUN ghmj-113 57 17 ( ( PUNCT ghmj-113 57 18 10 10 NUM ghmj-113 57 19 % % NOUN ghmj-113 57 20 , , PUNCT ghmj-113 57 21 35 35 NUM ghmj-113 57 22 % % NOUN ghmj-113 57 23 and and CCONJ ghmj-113 57 24 38 38 NUM ghmj-113 57 25 % % NOUN ghmj-113 57 26 amplitude amplitude NOUN ghmj-113 57 27 ) ) PUNCT ghmj-113 57 28 . . PUNCT ghmj-113 58 1 the the DET ghmj-113 58 2 mixture mixture NOUN ghmj-113 58 3 was be AUX ghmj-113 58 4 collected collect VERB ghmj-113 58 5 and and CCONJ ghmj-113 58 6 stored store VERB ghmj-113 58 7 using use VERB ghmj-113 58 8 the the DET ghmj-113 58 9 same same ADJ ghmj-113 58 10 procedure procedure NOUN ghmj-113 58 11 as as SCONJ ghmj-113 58 12 described describe VERB ghmj-113 58 13 above above ADV ghmj-113 58 14 . . PUNCT ghmj-113 59 1 characterization characterization NOUN ghmj-113 59 2 of of ADP ghmj-113 59 3 particle particle NOUN ghmj-113 59 4 size size NOUN ghmj-113 59 5 and and CCONJ ghmj-113 59 6 pdi pdi PROPN ghmj-113 59 7 value value NOUN ghmj-113 59 8 nps nps PROPN ghmj-113 59 9 were be AUX ghmj-113 59 10 dispersed disperse VERB ghmj-113 59 11 in in ADP ghmj-113 59 12 milli milli ADJ ghmj-113 59 13 q q NOUN ghmj-113 59 14 water water NOUN ghmj-113 59 15 at at ADP ghmj-113 59 16 concentration concentration NOUN ghmj-113 59 17 of of ADP ghmj-113 59 18 0.1 0.1 NUM ghmj-113 59 19 mg mg NUM ghmj-113 59 20 / / SYM ghmj-113 59 21 ml ml NOUN ghmj-113 59 22 before before ADP ghmj-113 59 23 characterization characterization NOUN ghmj-113 59 24 . . PUNCT ghmj-113 60 1 the the DET ghmj-113 60 2 size size NOUN ghmj-113 60 3 and and CCONJ ghmj-113 60 4 pdi pdi NOUN ghmj-113 60 5 value value NOUN ghmj-113 60 6 of of ADP ghmj-113 60 7 the the DET ghmj-113 60 8 particles particle NOUN ghmj-113 60 9 were be AUX ghmj-113 60 10 analyzed analyze VERB ghmj-113 60 11 using use VERB ghmj-113 60 12 nanosizer nanosizer NOUN ghmj-113 60 13 90 90 NUM ghmj-113 60 14 zs zs PROPN ghmj-113 60 15 ( ( PUNCT ghmj-113 60 16 malvern malvern PROPN ghmj-113 60 17 instrument instrument PROPN ghmj-113 60 18 ltd ltd PROPN ghmj-113 60 19 . . PROPN ghmj-113 60 20 , , PUNCT ghmj-113 60 21 malvern malvern PROPN ghmj-113 60 22 , , PUNCT ghmj-113 60 23 uk uk PROPN ghmj-113 60 24 ) ) PUNCT ghmj-113 60 25 at at ADP ghmj-113 60 26 25c 25c NUM ghmj-113 60 27 . . PUNCT ghmj-113 61 1 all all DET ghmj-113 61 2 measurements measurement NOUN ghmj-113 61 3 were be AUX ghmj-113 61 4 carried carry VERB ghmj-113 61 5 out out ADP ghmj-113 61 6 as as ADP ghmj-113 61 7 the the DET ghmj-113 61 8 average average NOUN ghmj-113 61 9 of of ADP ghmj-113 61 10 value value NOUN ghmj-113 61 11 with with ADP ghmj-113 61 12 triplicate triplicate NOUN ghmj-113 61 13 measurements measurement NOUN ghmj-113 61 14 and and CCONJ ghmj-113 61 15 at at ADV ghmj-113 61 16 least least ADV ghmj-113 61 17 10 10 NUM ghmj-113 61 18 runs run NOUN ghmj-113 61 19 within within ADP ghmj-113 61 20 each each DET ghmj-113 61 21 analysis analysis NOUN ghmj-113 61 22 . . PUNCT ghmj-113 62 1 the the DET ghmj-113 62 2 results result NOUN ghmj-113 62 3 were be AUX ghmj-113 62 4 reported report VERB ghmj-113 62 5 as as ADP ghmj-113 62 6 a a DET ghmj-113 62 7 mean mean NOUN ghmj-113 62 8 of of ADP ghmj-113 62 9 three three NUM ghmj-113 62 10 independent independent ADJ ghmj-113 62 11 readings reading NOUN ghmj-113 62 12   PROPN ghmj-113 62 13 standard standard ADJ ghmj-113 62 14 deviation deviation NOUN ghmj-113 62 15 . . PUNCT ghmj-113 63 1 results result NOUN ghmj-113 63 2 plga plga VERB ghmj-113 63 3 np np INTJ ghmj-113 63 4 size size NOUN ghmj-113 63 5 and and CCONJ ghmj-113 63 6 size size NOUN ghmj-113 63 7 distribution distribution NOUN ghmj-113 63 8 from from ADP ghmj-113 63 9 different different ADJ ghmj-113 63 10 mw mw NOUN ghmj-113 63 11 of of ADP ghmj-113 63 12 plga plga NOUN ghmj-113 63 13 in in ADP ghmj-113 63 14 this this DET ghmj-113 63 15 experiment experiment NOUN ghmj-113 63 16 , , PUNCT ghmj-113 63 17 the the DET ghmj-113 63 18 particles particle NOUN ghmj-113 63 19 prepared prepare VERB ghmj-113 63 20 by by ADP ghmj-113 63 21 60,000 60,000 NUM ghmj-113 63 22 and and CCONJ ghmj-113 63 23 80,000 80,000 NUM ghmj-113 63 24 g g NOUN ghmj-113 63 25 / / SYM ghmj-113 63 26 mol mol NOUN ghmj-113 63 27 plga plga NOUN ghmj-113 63 28 have have VERB ghmj-113 63 29 a a DET ghmj-113 63 30 size size NOUN ghmj-113 63 31 about about ADP ghmj-113 63 32 179 179 NUM ghmj-113 63 33 and and CCONJ ghmj-113 63 34 261 261 NUM ghmj-113 63 35 nm nm NOUN ghmj-113 63 36 respectively respectively ADV ghmj-113 63 37 ( ( PUNCT ghmj-113 63 38 figure figure NOUN ghmj-113 63 39 2 2 NUM ghmj-113 63 40 ) ) PUNCT ghmj-113 63 41 . . PUNCT ghmj-113 64 1 both both DET ghmj-113 64 2 nps nps PROPN ghmj-113 64 3 prepared prepare VERB ghmj-113 64 4 by by ADP ghmj-113 64 5 the the DET ghmj-113 64 6 two two NUM ghmj-113 64 7 mw mw NOUN ghmj-113 64 8 showed show VERB ghmj-113 64 9 pdi pdi ADJ ghmj-113 64 10 values value NOUN ghmj-113 64 11 less less ADJ ghmj-113 64 12 global global ADJ ghmj-113 64 13     SPACE ghmj-113 64 14 health health NOUN ghmj-113 64 15     SPACE ghmj-113 64 16 management management NOUN ghmj-113 64 17     SPACE ghmj-113 64 18 journal journal NOUN ghmj-113 64 19 , , PUNCT ghmj-113 64 20     SPACE ghmj-113 64 21 2017 2017 NUM ghmj-113 64 22 , , PUNCT ghmj-113 64 23     SPACE ghmj-113 64 24 vol vol NOUN ghmj-113 64 25 . . PUNCT ghmj-113 64 26     SPACE ghmj-113 64 27 1 1 NUM ghmj-113 64 28 , , PUNCT ghmj-113 64 29     SPACE ghmj-113 64 30 no no INTJ ghmj-113 64 31 . . PUNCT ghmj-113 64 32     SPACE ghmj-113 65 1 2 2 NUM ghmj-113 65 2     SPACE ghmj-113 65 3 34 34 NUM ghmj-113 65 4           SPACE ghmj-113 65 5 than than ADP ghmj-113 65 6 0.2 0.2 NUM ghmj-113 65 7 which which PRON ghmj-113 65 8 indicated indicate VERB ghmj-113 65 9 that that SCONJ ghmj-113 65 10 the the DET ghmj-113 65 11 nps nps PROPN ghmj-113 65 12 were be AUX ghmj-113 65 13 monodispersed monodisperse VERB ghmj-113 65 14 . . PUNCT ghmj-113 66 1 figure figure NOUN ghmj-113 66 2 2 2 NUM ghmj-113 66 3 . . PUNCT ghmj-113 66 4 characterization characterization NOUN ghmj-113 66 5 of of ADP ghmj-113 66 6 plga plga NOUN ghmj-113 66 7 nps nps PROPN ghmj-113 66 8 prepared prepare VERB ghmj-113 66 9 using use VERB ghmj-113 66 10 different different ADJ ghmj-113 66 11 molecular molecular ADJ ghmj-113 66 12 weight weight NOUN ghmj-113 66 13 of of ADP ghmj-113 66 14 plga plga NOUN ghmj-113 66 15 . . PUNCT ghmj-113 67 1 the the DET ghmj-113 67 2 5 5 NUM ghmj-113 67 3 % % NOUN ghmj-113 67 4 pva pva NOUN ghmj-113 67 5 , , PUNCT ghmj-113 67 6 etoac etoac VERB ghmj-113 67 7 was be AUX ghmj-113 67 8 applied apply VERB ghmj-113 67 9 to to ADP ghmj-113 67 10 the the DET ghmj-113 67 11 reaction reaction NOUN ghmj-113 67 12 and and CCONJ ghmj-113 67 13 38 38 NUM ghmj-113 67 14 % % NOUN ghmj-113 67 15 power power NOUN ghmj-113 67 16 of of ADP ghmj-113 67 17 sonication sonication NOUN ghmj-113 67 18 was be AUX ghmj-113 67 19 used use VERB ghmj-113 67 20 . . PUNCT ghmj-113 68 1 size size NOUN ghmj-113 68 2 ( ( PUNCT ghmj-113 68 3 black black ADJ ghmj-113 68 4 bars bar NOUN ghmj-113 68 5 , , PUNCT ghmj-113 68 6 left leave VERB ghmj-113 68 7 yaxis yaxis NOUN ghmj-113 68 8 ) ) PUNCT ghmj-113 68 9 and and CCONJ ghmj-113 68 10 pdi pdi PROPN ghmj-113 68 11 ( ( PUNCT ghmj-113 68 12 white white ADJ ghmj-113 68 13 bars bar NOUN ghmj-113 68 14 , , PUNCT ghmj-113 68 15 right right ADJ ghmj-113 68 16 y y NOUN ghmj-113 68 17 - - PUNCT ghmj-113 68 18 axis axis NOUN ghmj-113 68 19 ) ) PUNCT ghmj-113 68 20 values value NOUN ghmj-113 68 21 are be AUX ghmj-113 68 22 presented present VERB ghmj-113 68 23 . . PUNCT ghmj-113 69 1 plga plga VERB ghmj-113 69 2 np np INTJ ghmj-113 69 3 size size NOUN ghmj-113 69 4 and and CCONJ ghmj-113 69 5 size size NOUN ghmj-113 69 6 distribution distribution NOUN ghmj-113 69 7 from from ADP ghmj-113 69 8 different different ADJ ghmj-113 69 9 emulsifier emulsifier NOUN ghmj-113 69 10 concentrations concentration NOUN ghmj-113 69 11 and and CCONJ ghmj-113 69 12 organic organic ADJ ghmj-113 69 13 solvent solvent NOUN ghmj-113 69 14 types type NOUN ghmj-113 69 15 the the DET ghmj-113 69 16 sizes size NOUN ghmj-113 69 17 of of ADP ghmj-113 69 18 plga plga NOUN ghmj-113 69 19 nanoparticles nanoparticle NOUN ghmj-113 69 20 decreased decrease VERB ghmj-113 69 21 when when SCONJ ghmj-113 69 22 the the DET ghmj-113 69 23 pva pva NOUN ghmj-113 69 24 concentration concentration NOUN ghmj-113 69 25 was be AUX ghmj-113 69 26 increased increase VERB ghmj-113 69 27 ( ( PUNCT ghmj-113 69 28 figure figure NOUN ghmj-113 69 29 3 3 NUM ghmj-113 69 30 ) ) PUNCT ghmj-113 69 31 . . PUNCT ghmj-113 70 1 using use VERB ghmj-113 70 2 etoac etoac ADJ ghmj-113 70 3 as as ADP ghmj-113 70 4 solvent solvent NOUN ghmj-113 70 5 ( ( PUNCT ghmj-113 70 6 figure figure NOUN ghmj-113 70 7 3a 3a NUM ghmj-113 70 8 ) ) PUNCT ghmj-113 70 9 , , PUNCT ghmj-113 70 10 at at ADP ghmj-113 70 11 1 1 NUM ghmj-113 70 12 % % NOUN ghmj-113 70 13 ( ( PUNCT ghmj-113 70 14 w w NOUN ghmj-113 70 15 / / SYM ghmj-113 70 16 v v NOUN ghmj-113 70 17 ) ) PUNCT ghmj-113 70 18 pva pva NOUN ghmj-113 70 19 , , PUNCT ghmj-113 70 20 the the DET ghmj-113 70 21 particle particle NOUN ghmj-113 70 22 size size NOUN ghmj-113 70 23 was be AUX ghmj-113 70 24 about about ADV ghmj-113 70 25 259 259 NUM ghmj-113 70 26 nm nm NOUN ghmj-113 70 27 . . PUNCT ghmj-113 71 1 when when SCONJ ghmj-113 71 2 the the DET ghmj-113 71 3 pva pva NOUN ghmj-113 71 4 concentration concentration NOUN ghmj-113 71 5 was be AUX ghmj-113 71 6 increased increase VERB ghmj-113 71 7 to to ADP ghmj-113 71 8 5 5 NUM ghmj-113 71 9 % % NOUN ghmj-113 71 10 and and CCONJ ghmj-113 71 11 10 10 NUM ghmj-113 71 12 % % NOUN ghmj-113 71 13 ( ( PUNCT ghmj-113 71 14 w w NOUN ghmj-113 71 15 / / SYM ghmj-113 71 16 v v NOUN ghmj-113 71 17 ) ) PUNCT ghmj-113 71 18 , , PUNCT ghmj-113 71 19 the the DET ghmj-113 71 20 particle particle NOUN ghmj-113 71 21 sizes size NOUN ghmj-113 71 22 were be AUX ghmj-113 71 23 179 179 NUM ghmj-113 71 24 and and CCONJ ghmj-113 71 25 176 176 NUM ghmj-113 71 26 nm nm NOUN ghmj-113 71 27 , , PUNCT ghmj-113 71 28 respectively respectively ADV ghmj-113 71 29 . . PUNCT ghmj-113 72 1 it it PRON ghmj-113 72 2 was be AUX ghmj-113 72 3 found find VERB ghmj-113 72 4 that that SCONJ ghmj-113 72 5 at at ADP ghmj-113 72 6 5 5 NUM ghmj-113 72 7 % % NOUN ghmj-113 72 8 and and CCONJ ghmj-113 72 9 10 10 NUM ghmj-113 72 10 % % NOUN ghmj-113 72 11 ( ( PUNCT ghmj-113 72 12 w w NOUN ghmj-113 72 13 / / SYM ghmj-113 72 14 v v NOUN ghmj-113 72 15 ) ) PUNCT ghmj-113 72 16 pva pva NOUN ghmj-113 72 17 the the DET ghmj-113 72 18 particle particle NOUN ghmj-113 72 19 sizes size NOUN ghmj-113 72 20 were be AUX ghmj-113 72 21 not not PART ghmj-113 72 22 significantly significantly ADV ghmj-113 72 23 different different ADJ ghmj-113 72 24 . . PUNCT ghmj-113 73 1 the the DET ghmj-113 73 2 pdi pdi PROPN ghmj-113 73 3 value value NOUN ghmj-113 73 4 that that PRON ghmj-113 73 5 indicates indicate VERB ghmj-113 73 6 nanoparticle nanoparticle NOUN ghmj-113 73 7 size size NOUN ghmj-113 73 8 distribution distribution NOUN ghmj-113 73 9 showed show VERB ghmj-113 73 10 the the DET ghmj-113 73 11 value value NOUN ghmj-113 73 12 less less ADJ ghmj-113 73 13 than than ADP ghmj-113 73 14 0.2 0.2 NUM ghmj-113 73 15 which which PRON ghmj-113 73 16 suggested suggest VERB ghmj-113 73 17 that that PRON ghmj-113 73 18 plga plga NOUN ghmj-113 73 19 nanoparticles nanoparticle NOUN ghmj-113 73 20 prepared prepare VERB ghmj-113 73 21 by by ADP ghmj-113 73 22 these these DET ghmj-113 73 23 pva pva NOUN ghmj-113 73 24 concentrations concentration NOUN ghmj-113 73 25 were be AUX ghmj-113 73 26 monodispersed monodisperse VERB ghmj-113 73 27 . . PUNCT ghmj-113 74 1 similar similar ADJ ghmj-113 74 2 results result NOUN ghmj-113 74 3 were be AUX ghmj-113 74 4 also also ADV ghmj-113 74 5 obtained obtain VERB ghmj-113 74 6 from from ADP ghmj-113 74 7 nps nps PROPN ghmj-113 74 8 preparation preparation NOUN ghmj-113 74 9 using use VERB ghmj-113 74 10 dcm dcm PROPN ghmj-113 74 11 as as ADP ghmj-113 74 12 a a DET ghmj-113 74 13 solvent solvent NOUN ghmj-113 74 14 ( ( PUNCT ghmj-113 74 15 figure figure NOUN ghmj-113 74 16 3b 3b NUM ghmj-113 74 17 ) ) PUNCT ghmj-113 74 18 . . PUNCT ghmj-113 75 1 nps nps PROPN ghmj-113 75 2 size size NOUN ghmj-113 75 3 and and CCONJ ghmj-113 75 4 pdi pdi NOUN ghmj-113 75 5 values value NOUN ghmj-113 75 6 prepared prepare VERB ghmj-113 75 7 in in ADP ghmj-113 75 8 etoac etoac ADJ ghmj-113 75 9 were be AUX ghmj-113 75 10 smaller small ADJ ghmj-113 75 11 ( ( PUNCT ghmj-113 75 12 170 170 NUM ghmj-113 75 13 - - SYM ghmj-113 75 14 220 220 NUM ghmj-113 75 15 nm nm NOUN ghmj-113 75 16 ) ) PUNCT ghmj-113 75 17 ( ( PUNCT ghmj-113 75 18 figure figure NOUN ghmj-113 75 19 3a 3a NUM ghmj-113 75 20 ) ) PUNCT ghmj-113 75 21 than than ADP ghmj-113 75 22 the the DET ghmj-113 75 23 particles particle NOUN ghmj-113 75 24 that that PRON ghmj-113 75 25 prepared prepare VERB ghmj-113 75 26 in in ADP ghmj-113 75 27 dcm dcm PROPN ghmj-113 75 28 ( ( PUNCT ghmj-113 75 29 300 300 NUM ghmj-113 75 30 - - SYM ghmj-113 75 31 500 500 NUM ghmj-113 75 32 nm nm NOUN ghmj-113 75 33 ) ) PUNCT ghmj-113 75 34 ( ( PUNCT ghmj-113 75 35 figure figure NOUN ghmj-113 75 36 3b 3b NUM ghmj-113 75 37 ) ) PUNCT ghmj-113 75 38 . . PUNCT ghmj-113 76 1 figure figure VERB ghmj-113 76 2 3 3 NUM ghmj-113 76 3 . . PUNCT ghmj-113 76 4 characterization characterization NOUN ghmj-113 76 5 of of ADP ghmj-113 76 6 plga plga NOUN ghmj-113 76 7 nps nps PROPN ghmj-113 76 8 prepared prepare VERB ghmj-113 76 9 using use VERB ghmj-113 76 10 different different ADJ ghmj-113 76 11 pva pva NOUN ghmj-113 76 12 concentrations concentration NOUN ghmj-113 76 13 and and CCONJ ghmj-113 76 14 different different ADJ ghmj-113 76 15 solvents solvent NOUN ghmj-113 76 16 . . PUNCT ghmj-113 77 1 a a PRON ghmj-113 77 2 ) ) PUNCT ghmj-113 77 3 nps nps PROPN ghmj-113 77 4 prepared prepare VERB ghmj-113 77 5 using use VERB ghmj-113 77 6 etoac etoac ADJ ghmj-113 77 7 , , PUNCT ghmj-113 77 8 b b X ghmj-113 77 9 ) ) PUNCT ghmj-113 77 10 nps nps PROPN ghmj-113 77 11 prepared prepare VERB ghmj-113 77 12 using use VERB ghmj-113 77 13 dcm dcm PROPN ghmj-113 77 14 . . PUNCT ghmj-113 78 1 the the DET ghmj-113 78 2 60,000 60,000 NUM ghmj-113 78 3 g g NOUN ghmj-113 78 4 / / SYM ghmj-113 78 5 mol mol NOUN ghmj-113 78 6 plga plga NOUN ghmj-113 78 7 , , PUNCT ghmj-113 78 8 and and CCONJ ghmj-113 78 9 solvent solvent NOUN ghmj-113 78 10 were be AUX ghmj-113 78 11 applied apply VERB ghmj-113 78 12 to to ADP ghmj-113 78 13 the the DET ghmj-113 78 14 reaction reaction NOUN ghmj-113 78 15 and and CCONJ ghmj-113 78 16 38 38 NUM ghmj-113 78 17 % % NOUN ghmj-113 78 18 power power NOUN ghmj-113 78 19 of of ADP ghmj-113 78 20 sonication sonication NOUN ghmj-113 78 21 was be AUX ghmj-113 78 22 used use VERB ghmj-113 78 23 . . PUNCT ghmj-113 79 1 size size NOUN ghmj-113 79 2 ( ( PUNCT ghmj-113 79 3 black black ADJ ghmj-113 79 4 bar bar NOUN ghmj-113 79 5 , , PUNCT ghmj-113 79 6 left leave VERB ghmj-113 79 7 y y NOUN ghmj-113 79 8 - - PUNCT ghmj-113 79 9 axis axis NOUN ghmj-113 79 10 ) ) PUNCT ghmj-113 79 11 and and CCONJ ghmj-113 79 12 pdi pdi PROPN ghmj-113 79 13 ( ( PUNCT ghmj-113 79 14 white white ADJ ghmj-113 79 15 bars bar NOUN ghmj-113 79 16 , , PUNCT ghmj-113 79 17 right right ADJ ghmj-113 79 18 y y NOUN ghmj-113 79 19 - - PUNCT ghmj-113 79 20 axis axis NOUN ghmj-113 79 21 ) ) PUNCT ghmj-113 79 22 values value NOUN ghmj-113 79 23 are be AUX ghmj-113 79 24 presented present VERB ghmj-113 79 25 . . PUNCT ghmj-113 80 1 plga plga VERB ghmj-113 80 2 np np INTJ ghmj-113 80 3 size size NOUN ghmj-113 80 4 and and CCONJ ghmj-113 80 5 size size NOUN ghmj-113 80 6 distribution distribution NOUN ghmj-113 80 7 from from ADP ghmj-113 80 8 different different ADJ ghmj-113 80 9 power power NOUN ghmj-113 80 10 of of ADP ghmj-113 80 11 ultrasonication ultrasonication NOUN ghmj-113 80 12 nps nps PROPN ghmj-113 80 13 prepared prepare VERB ghmj-113 80 14 by by ADP ghmj-113 80 15 38 38 NUM ghmj-113 80 16 % % NOUN ghmj-113 80 17 sonication sonication NOUN ghmj-113 80 18 were be AUX ghmj-113 80 19 of of ADP ghmj-113 80 20 smaller small ADJ ghmj-113 80 21 size size NOUN ghmj-113 80 22 ( ( PUNCT ghmj-113 80 23 179 179 NUM ghmj-113 80 24 nm nm NOUN ghmj-113 80 25 ) ) PUNCT ghmj-113 80 26 than than ADP ghmj-113 80 27 particles particle NOUN ghmj-113 80 28 prepared prepare VERB ghmj-113 80 29 by by ADP ghmj-113 80 30 10 10 NUM ghmj-113 80 31 % % NOUN ghmj-113 80 32 ( ( PUNCT ghmj-113 80 33 246 246 NUM ghmj-113 80 34 nm nm NOUN ghmj-113 80 35 ) ) PUNCT ghmj-113 80 36 . . PUNCT ghmj-113 81 1 this this DET ghmj-113 81 2 result result NOUN ghmj-113 81 3 indicated indicate VERB ghmj-113 81 4 that that SCONJ ghmj-113 81 5 higher high ADJ ghmj-113 81 6 power power NOUN ghmj-113 81 7 of of ADP ghmj-113 81 8 sonication sonication NOUN ghmj-113 81 9 induced induce VERB ghmj-113 81 10 the the DET ghmj-113 81 11 production production NOUN ghmj-113 81 12 of of ADP ghmj-113 81 13 smaller small ADJ ghmj-113 81 14 size size NOUN ghmj-113 81 15 of of ADP ghmj-113 81 16 nps nps PROPN ghmj-113 81 17 . . PUNCT ghmj-113 82 1 the the DET ghmj-113 82 2 pdi pdi PROPN ghmj-113 82 3 values value NOUN ghmj-113 82 4 from from ADP ghmj-113 82 5 both both DET ghmj-113 82 6 conditions condition NOUN ghmj-113 82 7 were be AUX ghmj-113 82 8 less less ADJ ghmj-113 82 9 than than ADP ghmj-113 82 10 0.2 0.2 NUM ghmj-113 82 11 that that PRON ghmj-113 82 12 represented represent VERB ghmj-113 82 13 monodispersity monodispersity NOUN ghmj-113 82 14 of of ADP ghmj-113 82 15 nps nps PROPN ghmj-113 82 16 ( ( PUNCT ghmj-113 82 17 figure figure NOUN ghmj-113 82 18 4 4 NUM ghmj-113 82 19 ) ) PUNCT ghmj-113 82 20 . . PUNCT ghmj-113 83 1 35 35 NUM ghmj-113 83 2                                                                   SPACE ghmj-113 83 3 global global ADJ ghmj-113 83 4     SPACE ghmj-113 83 5 health health NOUN ghmj-113 83 6     SPACE ghmj-113 83 7 management management NOUN ghmj-113 83 8     SPACE ghmj-113 83 9 journal journal NOUN ghmj-113 83 10 , , PUNCT ghmj-113 83 11     SPACE ghmj-113 83 12 2017 2017 NUM ghmj-113 83 13 , , PUNCT ghmj-113 83 14     SPACE ghmj-113 83 15 vol vol NOUN ghmj-113 83 16 . . PUNCT ghmj-113 83 17     SPACE ghmj-113 83 18 1 1 NUM ghmj-113 83 19 , , PUNCT ghmj-113 83 20     SPACE ghmj-113 83 21 no no INTJ ghmj-113 83 22 . . PUNCT ghmj-113 83 23     SPACE ghmj-113 83 24 2 2 NUM ghmj-113 83 25                 SPACE ghmj-113 83 26 figure figure NOUN ghmj-113 83 27 4 4 NUM ghmj-113 83 28 . . PUNCT ghmj-113 83 29 characterization characterization NOUN ghmj-113 83 30 of of ADP ghmj-113 83 31 plga plga NOUN ghmj-113 83 32 nps nps PROPN ghmj-113 83 33 prepared prepare VERB ghmj-113 83 34 by by ADP ghmj-113 83 35 using use VERB ghmj-113 83 36 different different ADJ ghmj-113 83 37 ultrasonication ultrasonication NOUN ghmj-113 83 38 power power NOUN ghmj-113 83 39 . . PUNCT ghmj-113 84 1 the the DET ghmj-113 84 2 5 5 NUM ghmj-113 84 3 % % NOUN ghmj-113 84 4 pva pva NOUN ghmj-113 84 5 , , PUNCT ghmj-113 84 6 60,000 60,000 NUM ghmj-113 84 7 g g NOUN ghmj-113 84 8 / / SYM ghmj-113 84 9 mol mol NOUN ghmj-113 84 10 plga plga NOUN ghmj-113 84 11 and and CCONJ ghmj-113 84 12 etoac etoac ADJ ghmj-113 84 13 were be AUX ghmj-113 84 14 applied apply VERB ghmj-113 84 15 to to ADP ghmj-113 84 16 the the DET ghmj-113 84 17 reaction reaction NOUN ghmj-113 84 18 . . PUNCT ghmj-113 85 1 size size NOUN ghmj-113 85 2 ( ( PUNCT ghmj-113 85 3 black black ADJ ghmj-113 85 4 bars bar NOUN ghmj-113 85 5 , , PUNCT ghmj-113 85 6 left leave VERB ghmj-113 85 7 y y NOUN ghmj-113 85 8 - - PUNCT ghmj-113 85 9 axis axis NOUN ghmj-113 85 10 ) ) PUNCT ghmj-113 85 11 and and CCONJ ghmj-113 85 12 pdi pdi PROPN ghmj-113 85 13 ( ( PUNCT ghmj-113 85 14 white white ADJ ghmj-113 85 15 bars bar NOUN ghmj-113 85 16 , , PUNCT ghmj-113 85 17 right right ADJ ghmj-113 85 18 y y NOUN ghmj-113 85 19 - - PUNCT ghmj-113 85 20 axis axis NOUN ghmj-113 85 21 ) ) PUNCT ghmj-113 85 22 values value NOUN ghmj-113 85 23 are be AUX ghmj-113 85 24 presented present VERB ghmj-113 85 25 . . PUNCT ghmj-113 86 1 plga plga VERB ghmj-113 86 2 np np INTJ ghmj-113 86 3 size size NOUN ghmj-113 86 4 after after ADP ghmj-113 86 5 long long ADJ ghmj-113 86 6 storage storage NOUN ghmj-113 86 7 in in ADP ghmj-113 86 8 aqueous aqueous ADJ ghmj-113 86 9 solution solution NOUN ghmj-113 86 10 to to PART ghmj-113 86 11 use use VERB ghmj-113 86 12 nps nps PROPN ghmj-113 86 13 as as ADP ghmj-113 86 14 a a DET ghmj-113 86 15 drug drug NOUN ghmj-113 86 16 delivery delivery NOUN ghmj-113 86 17 system system NOUN ghmj-113 86 18 the the DET ghmj-113 86 19 stability stability NOUN ghmj-113 86 20 of of ADP ghmj-113 86 21 drug drug NOUN ghmj-113 86 22 carrier carrier NOUN ghmj-113 86 23 is be AUX ghmj-113 86 24 important important ADJ ghmj-113 86 25 . . PUNCT ghmj-113 87 1 figure figure NOUN ghmj-113 87 2 5 5 NUM ghmj-113 87 3 illustrates illustrate VERB ghmj-113 87 4 examples example NOUN ghmj-113 87 5 of of ADP ghmj-113 87 6 nps nps PROPN ghmj-113 87 7 size size NOUN ghmj-113 87 8 after after ADP ghmj-113 87 9 long long ADJ ghmj-113 87 10 storage storage NOUN ghmj-113 87 11 in in ADP ghmj-113 87 12 aqueous aqueous ADJ ghmj-113 87 13 solution solution NOUN ghmj-113 87 14 up up ADP ghmj-113 87 15 to to PART ghmj-113 87 16 7 7 NUM ghmj-113 87 17 months month NOUN ghmj-113 87 18 . . PUNCT ghmj-113 88 1 the the DET ghmj-113 88 2 nps nps PROPN ghmj-113 88 3 size size NOUN ghmj-113 88 4 remains remain VERB ghmj-113 88 5 similar similar ADJ ghmj-113 88 6 to to ADP ghmj-113 88 7 short short ADJ ghmj-113 88 8 storage storage NOUN ghmj-113 88 9 time time NOUN ghmj-113 88 10 and and CCONJ ghmj-113 88 11 no no DET ghmj-113 88 12 sign sign NOUN ghmj-113 88 13 of of ADP ghmj-113 88 14 aggregation aggregation NOUN ghmj-113 88 15 was be AUX ghmj-113 88 16 observed observe VERB ghmj-113 88 17 . . PUNCT ghmj-113 89 1 this this DET ghmj-113 89 2 result result NOUN ghmj-113 89 3 suggested suggest VERB ghmj-113 89 4 that that SCONJ ghmj-113 89 5 the the DET ghmj-113 89 6 obtained obtain VERB ghmj-113 89 7 plga plga NOUN ghmj-113 89 8 nps nps PROPN ghmj-113 89 9 are be AUX ghmj-113 89 10 stable stable ADJ ghmj-113 89 11 up up ADP ghmj-113 89 12 to to PART ghmj-113 89 13 7 7 NUM ghmj-113 89 14 months month NOUN ghmj-113 89 15 and and CCONJ ghmj-113 89 16 has have VERB ghmj-113 89 17 high high ADJ ghmj-113 89 18 potential potential NOUN ghmj-113 89 19 for for ADP ghmj-113 89 20 development development NOUN ghmj-113 89 21 as as ADP ghmj-113 89 22 a a DET ghmj-113 89 23 drug drug NOUN ghmj-113 89 24 carrier carrier NOUN ghmj-113 89 25 system system NOUN ghmj-113 89 26 . . PUNCT ghmj-113 90 1 figure figure NOUN ghmj-113 90 2 5 5 NUM ghmj-113 90 3 . . PUNCT ghmj-113 90 4 characterization characterization NOUN ghmj-113 90 5 of of ADP ghmj-113 90 6 plga plga NOUN ghmj-113 90 7 nps nps PROPN ghmj-113 90 8 prepared prepare VERB ghmj-113 90 9 by by ADP ghmj-113 90 10 using use VERB ghmj-113 90 11 different different ADJ ghmj-113 90 12 pva pva NOUN ghmj-113 90 13 concentrations concentration NOUN ghmj-113 90 14 and and CCONJ ghmj-113 90 15 after after ADP ghmj-113 90 16 long long ADJ ghmj-113 90 17 term term NOUN ghmj-113 90 18 storage storage NOUN ghmj-113 90 19 . . PUNCT ghmj-113 91 1 nps nps PROPN ghmj-113 91 2 prepared prepare VERB ghmj-113 91 3 using use VERB ghmj-113 91 4 60,000 60,000 NUM ghmj-113 91 5 g g NOUN ghmj-113 91 6 / / SYM ghmj-113 91 7 mol mol NOUN ghmj-113 91 8 plga plga NOUN ghmj-113 91 9 , , PUNCT ghmj-113 91 10 and and CCONJ ghmj-113 91 11 etoac etoac ADJ ghmj-113 91 12 were be AUX ghmj-113 91 13 applied apply VERB ghmj-113 91 14 to to ADP ghmj-113 91 15 the the DET ghmj-113 91 16 reaction reaction NOUN ghmj-113 91 17 and and CCONJ ghmj-113 91 18 35 35 NUM ghmj-113 91 19 % % NOUN ghmj-113 91 20 power power NOUN ghmj-113 91 21 of of ADP ghmj-113 91 22 sonication sonication NOUN ghmj-113 91 23 was be AUX ghmj-113 91 24 used use VERB ghmj-113 91 25 . . PUNCT ghmj-113 92 1 size size NOUN ghmj-113 92 2 after after ADP ghmj-113 92 3 one one NUM ghmj-113 92 4 week week NOUN ghmj-113 92 5 ( ( PUNCT ghmj-113 92 6 black black ADJ ghmj-113 92 7 bars bar NOUN ghmj-113 92 8 ) ) PUNCT ghmj-113 92 9 and and CCONJ ghmj-113 92 10 size size NOUN ghmj-113 92 11 after after ADP ghmj-113 92 12 7 7 NUM ghmj-113 92 13 months month NOUN ghmj-113 92 14 ( ( PUNCT ghmj-113 92 15 white white ADJ ghmj-113 92 16 bars bar NOUN ghmj-113 92 17 ) ) PUNCT ghmj-113 92 18 are be AUX ghmj-113 92 19 presented present VERB ghmj-113 92 20 . . PUNCT ghmj-113 93 1 discussion discussion NOUN ghmj-113 93 2 plga plga VERB ghmj-113 93 3 np np INTJ ghmj-113 93 4 size size NOUN ghmj-113 93 5 is be AUX ghmj-113 93 6 easily easily ADV ghmj-113 93 7 tunable tunable ADJ ghmj-113 93 8 by by ADP ghmj-113 93 9 simple simple ADJ ghmj-113 93 10 changes change NOUN ghmj-113 93 11 in in ADP ghmj-113 93 12 the the DET ghmj-113 93 13 synthesis synthesis NOUN ghmj-113 93 14 parameters parameter NOUN ghmj-113 93 15 . . PUNCT ghmj-113 94 1 with with ADP ghmj-113 94 2 high high ADJ ghmj-113 94 3 mw mw NOUN ghmj-113 94 4 of of ADP ghmj-113 94 5 plga plga NOUN ghmj-113 94 6 a a DET ghmj-113 94 7 larger large ADJ ghmj-113 94 8 particle particle NOUN ghmj-113 94 9 size size NOUN ghmj-113 94 10 is be AUX ghmj-113 94 11 produced produce VERB ghmj-113 94 12 because because SCONJ ghmj-113 94 13 the the DET ghmj-113 94 14 long long ADJ ghmj-113 94 15 chain chain NOUN ghmj-113 94 16 of of ADP ghmj-113 94 17 polymer polymer NOUN ghmj-113 94 18 can can AUX ghmj-113 94 19 induce induce VERB ghmj-113 94 20 larger large ADJ ghmj-113 94 21 oil oil NOUN ghmj-113 94 22 droplets droplet NOUN ghmj-113 94 23 [ [ X ghmj-113 94 24 17 17 NUM ghmj-113 94 25 ] ] PUNCT ghmj-113 94 26 . . PUNCT ghmj-113 95 1 data datum NOUN ghmj-113 95 2 show show VERB ghmj-113 95 3 that that SCONJ ghmj-113 95 4 pva pva NOUN ghmj-113 95 5 can can AUX ghmj-113 95 6 be be AUX ghmj-113 95 7 used use VERB ghmj-113 95 8 to to PART ghmj-113 95 9 stabilize stabilize VERB ghmj-113 95 10 emulsion emulsion NOUN ghmj-113 95 11 and and CCONJ ghmj-113 95 12 lead lead VERB ghmj-113 95 13 to to ADP ghmj-113 95 14 formation formation NOUN ghmj-113 95 15 of of ADP ghmj-113 95 16 small small ADJ ghmj-113 95 17 and and CCONJ ghmj-113 95 18 monodispersed monodisperse VERB ghmj-113 95 19 particles particle NOUN ghmj-113 95 20 [ [ X ghmj-113 95 21 18 18 NUM ghmj-113 95 22 , , PUNCT ghmj-113 95 23 19 19 NUM ghmj-113 95 24 ] ] PUNCT ghmj-113 95 25 . . PUNCT ghmj-113 96 1 therefore therefore ADV ghmj-113 96 2 , , PUNCT ghmj-113 96 3 when when SCONJ ghmj-113 96 4 increasing increase VERB ghmj-113 96 5 the the DET ghmj-113 96 6 concentration concentration NOUN ghmj-113 96 7 of of ADP ghmj-113 96 8 pva pva NOUN ghmj-113 96 9 the the DET ghmj-113 96 10 size size NOUN ghmj-113 96 11 of of ADP ghmj-113 96 12 particles particle NOUN ghmj-113 96 13 tend tend VERB ghmj-113 96 14 to to PART ghmj-113 96 15 decrease decrease VERB ghmj-113 96 16 . . PUNCT ghmj-113 97 1 in in ADP ghmj-113 97 2 addition addition NOUN ghmj-113 97 3 , , PUNCT ghmj-113 97 4 organic organic ADJ ghmj-113 97 5 solvent solvent NOUN ghmj-113 97 6 can can AUX ghmj-113 97 7 affect affect VERB ghmj-113 97 8 the the DET ghmj-113 97 9 particles particle NOUN ghmj-113 97 10 size size NOUN ghmj-113 97 11 of of ADP ghmj-113 97 12 plga plga NOUN ghmj-113 97 13 nps nps PROPN ghmj-113 97 14 . . PUNCT ghmj-113 98 1 the the DET ghmj-113 98 2 nps nps PROPN ghmj-113 98 3 prepared prepare VERB ghmj-113 98 4 by by ADP ghmj-113 98 5 dcm dcm PROPN ghmj-113 98 6 were be AUX ghmj-113 98 7 bigger big ADJ ghmj-113 98 8 than than ADP ghmj-113 98 9 particles particle NOUN ghmj-113 98 10 prepared prepare VERB ghmj-113 98 11 by by ADP ghmj-113 98 12 etoac etoac ADJ ghmj-113 98 13 . . PUNCT ghmj-113 99 1 these these DET ghmj-113 99 2 results result NOUN ghmj-113 99 3 could could AUX ghmj-113 99 4 be be AUX ghmj-113 99 5 due due ADJ ghmj-113 99 6 to to ADP ghmj-113 99 7 different different ADJ ghmj-113 99 8 properties property NOUN ghmj-113 99 9 of of ADP ghmj-113 99 10 the the DET ghmj-113 99 11 solvent solvent NOUN ghmj-113 99 12 . . PUNCT ghmj-113 100 1 dcm dcm PROPN ghmj-113 100 2 is be AUX ghmj-113 100 3 a a DET ghmj-113 100 4 non non ADJ ghmj-113 100 5 - - ADJ ghmj-113 100 6 miscible miscible ADJ ghmj-113 100 7 solvent solvent NOUN ghmj-113 100 8 in in ADP ghmj-113 100 9 water water NOUN ghmj-113 100 10 , , PUNCT ghmj-113 100 11 unlike unlike ADP ghmj-113 100 12 etoac etoac ADV ghmj-113 100 13 . . PUNCT ghmj-113 101 1 therefore therefore ADV ghmj-113 101 2 , , PUNCT ghmj-113 101 3 dcm dcm PROPN ghmj-113 101 4 has have VERB ghmj-113 101 5 a a DET ghmj-113 101 6 higher high ADJ ghmj-113 101 7 surface surface NOUN ghmj-113 101 8 tension tension NOUN ghmj-113 101 9 in in ADP ghmj-113 101 10 oil oil NOUN ghmj-113 101 11 droplets droplet NOUN ghmj-113 101 12 from from ADP ghmj-113 101 13 the the DET ghmj-113 101 14 emulsion emulsion NOUN ghmj-113 101 15 step step NOUN ghmj-113 101 16 , , PUNCT ghmj-113 101 17 resulting result VERB ghmj-113 101 18 in in ADP ghmj-113 101 19 larger large ADJ ghmj-113 101 20 nanoparticles nanoparticle NOUN ghmj-113 101 21 [ [ X ghmj-113 101 22 20 20 NUM ghmj-113 101 23 ] ] PUNCT ghmj-113 101 24 . . PUNCT ghmj-113 102 1 apart apart ADV ghmj-113 102 2 from from ADP ghmj-113 102 3 mw mw NOUN ghmj-113 102 4 , , PUNCT ghmj-113 102 5 emulsifier emulsifier NOUN ghmj-113 102 6 concentrations concentration NOUN ghmj-113 102 7 and and CCONJ ghmj-113 102 8 organic organic ADJ ghmj-113 102 9 solvent solvent NOUN ghmj-113 102 10 type type NOUN ghmj-113 102 11 , , PUNCT ghmj-113 102 12 power power NOUN ghmj-113 102 13 of of ADP ghmj-113 102 14 sonication sonication NOUN ghmj-113 102 15 can can AUX ghmj-113 102 16 affect affect VERB ghmj-113 102 17 particle particle NOUN ghmj-113 102 18 size size NOUN ghmj-113 102 19 . . PUNCT ghmj-113 103 1 the the DET ghmj-113 103 2 power power NOUN ghmj-113 103 3 of of ADP ghmj-113 103 4 sonication sonication NOUN ghmj-113 103 5 applied apply VERB ghmj-113 103 6 to to ADP ghmj-113 103 7 the the DET ghmj-113 103 8 emulsion emulsion NOUN ghmj-113 103 9 step step NOUN ghmj-113 103 10 can can AUX ghmj-113 103 11 disrupt disrupt VERB ghmj-113 103 12 the the DET ghmj-113 103 13 surface surface NOUN ghmj-113 103 14 tension tension NOUN ghmj-113 103 15 of of ADP ghmj-113 103 16 the the DET ghmj-113 103 17 larger large ADJ ghmj-113 103 18 oil oil NOUN ghmj-113 103 19 drops drop NOUN ghmj-113 103 20 to to PART ghmj-113 103 21 create create VERB ghmj-113 103 22 a a DET ghmj-113 103 23 smaller small ADJ ghmj-113 103 24 oil oil NOUN ghmj-113 103 25 drop drop NOUN ghmj-113 103 26 which which PRON ghmj-113 103 27 leads lead VERB ghmj-113 103 28 to to ADP ghmj-113 103 29 formation formation NOUN ghmj-113 103 30 of of ADP ghmj-113 103 31 smaller small ADJ ghmj-113 103 32 particles particle NOUN ghmj-113 103 33 as as SCONJ ghmj-113 103 34 previously previously ADV ghmj-113 103 35 observed observe VERB ghmj-113 103 36 [ [ X ghmj-113 103 37 21 21 NUM ghmj-113 103 38 ] ] PUNCT ghmj-113 103 39 . . PUNCT ghmj-113 104 1 conclusion conclusion VERB ghmj-113 104 2 different different ADJ ghmj-113 104 3 sizes size NOUN ghmj-113 104 4 of of ADP ghmj-113 104 5 plga plga NOUN ghmj-113 104 6 nps nps PROPN ghmj-113 104 7 were be AUX ghmj-113 104 8 successfully successfully ADV ghmj-113 104 9 prepared prepare VERB ghmj-113 104 10 by by ADP ghmj-113 104 11 changing change VERB ghmj-113 104 12 each each PRON ghmj-113 104 13 of of ADP ghmj-113 104 14 four four NUM ghmj-113 104 15 synthesis synthesis NOUN ghmj-113 104 16 parameters parameter NOUN ghmj-113 104 17 . . PUNCT ghmj-113 105 1 the the DET ghmj-113 105 2 factors factor NOUN ghmj-113 105 3 that that PRON ghmj-113 105 4 contribute contribute VERB ghmj-113 105 5 to to ADP ghmj-113 105 6 the the DET ghmj-113 105 7 achievement achievement NOUN ghmj-113 105 8 of of ADP ghmj-113 105 9 desirable desirable ADJ ghmj-113 105 10 size size NOUN ghmj-113 105 11 are be AUX ghmj-113 105 12 plga plga NOUN ghmj-113 105 13 mw mw X ghmj-113 105 14 , , PUNCT ghmj-113 105 15 pva pva NOUN ghmj-113 105 16 concentrations concentration NOUN ghmj-113 105 17 , , PUNCT ghmj-113 105 18 organic organic ADJ ghmj-113 105 19 solvent solvent NOUN ghmj-113 105 20 type type NOUN ghmj-113 105 21 , , PUNCT ghmj-113 105 22 and and CCONJ ghmj-113 105 23 sonication sonication NOUN ghmj-113 105 24 power power NOUN ghmj-113 105 25 . . PUNCT ghmj-113 106 1 the the DET ghmj-113 106 2 nps nps PROPN ghmj-113 106 3 obtained obtain VERB ghmj-113 106 4 are be AUX ghmj-113 106 5 stable stable ADJ ghmj-113 106 6 in in ADP ghmj-113 106 7 aqueous aqueous ADJ ghmj-113 106 8 solution solution NOUN ghmj-113 106 9 , , PUNCT ghmj-113 106 10 and and CCONJ ghmj-113 106 11 therefore therefore ADV ghmj-113 106 12 are be AUX ghmj-113 106 13 suitable suitable ADJ ghmj-113 106 14 for for ADP ghmj-113 106 15 further further ADJ ghmj-113 106 16 development development NOUN ghmj-113 106 17 as as ADP ghmj-113 106 18 a a DET ghmj-113 106 19 drug drug NOUN ghmj-113 106 20 carrier carrier NOUN ghmj-113 106 21 system system NOUN ghmj-113 106 22 for for ADP ghmj-113 106 23 cancer cancer NOUN ghmj-113 106 24 treatment treatment NOUN ghmj-113 106 25 . . PUNCT ghmj-113 107 1 acknowledgements acknowledgement NOUN ghmj-113 107 2 this this DET ghmj-113 107 3 project project NOUN ghmj-113 107 4 was be AUX ghmj-113 107 5 supported support VERB ghmj-113 107 6 by by ADP ghmj-113 107 7 mahidol mahidol PROPN ghmj-113 107 8 university university NOUN ghmj-113 107 9 and and CCONJ ghmj-113 107 10 faculty faculty NOUN ghmj-113 107 11 of of ADP ghmj-113 107 12 science science NOUN ghmj-113 107 13 , , PUNCT ghmj-113 107 14 mahidol mahidol PROPN ghmj-113 107 15 university university PROPN ghmj-113 107 16 , , PUNCT ghmj-113 107 17 development development NOUN ghmj-113 107 18 and and CCONJ ghmj-113 107 19 promotion promotion NOUN ghmj-113 107 20 of of ADP ghmj-113 107 21 science science NOUN ghmj-113 107 22 and and CCONJ ghmj-113 107 23 technology technology NOUN ghmj-113 107 24 talents talent NOUN ghmj-113 107 25 project project NOUN ghmj-113 107 26 . . PUNCT ghmj-113 108 1 this this DET ghmj-113 108 2 project project NOUN ghmj-113 108 3 was be AUX ghmj-113 108 4 partially partially ADV ghmj-113 108 5 supported support VERB ghmj-113 108 6 by by ADP ghmj-113 108 7 cif cif PROPN ghmj-113 108 8 grant grant PROPN ghmj-113 108 9 , , PUNCT ghmj-113 108 10 faculty faculty NOUN ghmj-113 108 11 of of ADP ghmj-113 108 12 science science NOUN ghmj-113 108 13 , , PUNCT ghmj-113 108 14 mahidol mahidol PROPN ghmj-113 108 15 university university NOUN ghmj-113 108 16 . . PUNCT ghmj-113 109 1 ks ks PROPN ghmj-113 109 2 was be AUX ghmj-113 109 3 supported support VERB ghmj-113 109 4 by by ADP ghmj-113 109 5 research research NOUN ghmj-113 109 6 assistantships assistantship NOUN ghmj-113 109 7 , , PUNCT ghmj-113 109 8 faculty faculty NOUN ghmj-113 109 9 of of ADP ghmj-113 109 10 graduate graduate NOUN ghmj-113 109 11 studies study NOUN ghmj-113 109 12 , , PUNCT ghmj-113 109 13 mahidol mahidol PROPN ghmj-113 109 14 university university PROPN ghmj-113 109 15 . . PUNCT ghmj-113 110 1 pc pc PROPN ghmj-113 110 2 was be AUX ghmj-113 110 3 supported support VERB ghmj-113 110 4 by by ADP ghmj-113 110 5 science science NOUN ghmj-113 110 6 achievement achievement NOUN ghmj-113 110 7 scholarship scholarship NOUN ghmj-113 110 8 of of ADP ghmj-113 110 9 thailand thailand PROPN ghmj-113 110 10 . . PUNCT ghmj-113 111 1 sp sp PROPN ghmj-113 111 2 was be AUX ghmj-113 111 3 supported support VERB ghmj-113 111 4 by by ADP ghmj-113 111 5 development development NOUN ghmj-113 111 6 and and CCONJ ghmj-113 111 7 promotion promotion NOUN ghmj-113 111 8 of of ADP ghmj-113 111 9 science science NOUN ghmj-113 111 10 and and CCONJ ghmj-113 111 11 technology technology NOUN ghmj-113 111 12 talents talent NOUN ghmj-113 111 13 project project NOUN ghmj-113 111 14 . . PUNCT ghmj-113 112 1 global global ADJ ghmj-113 112 2     SPACE ghmj-113 112 3 health health NOUN ghmj-113 112 4     SPACE ghmj-113 112 5 management management NOUN ghmj-113 112 6     SPACE ghmj-113 112 7 journal journal NOUN ghmj-113 112 8 , , PUNCT ghmj-113 112 9     SPACE ghmj-113 112 10 2017 2017 NUM ghmj-113 112 11 , , PUNCT ghmj-113 112 12     SPACE ghmj-113 112 13 vol vol NOUN ghmj-113 112 14 . . PUNCT ghmj-113 112 15     SPACE ghmj-113 112 16 1 1 NUM ghmj-113 112 17 , , PUNCT ghmj-113 112 18     SPACE ghmj-113 113 1 no no INTJ ghmj-113 113 2 . . PUNCT ghmj-113 113 3     SPACE ghmj-113 113 4 2 2 NUM ghmj-113 113 5     SPACE ghmj-113 113 6 36 36 NUM ghmj-113 113 7           SPACE ghmj-113 113 8 conflict conflict NOUN ghmj-113 113 9 of of ADP ghmj-113 113 10 interests interest NOUN ghmj-113 113 11 the the DET ghmj-113 113 12 authors author NOUN ghmj-113 113 13 have have VERB ghmj-113 113 14 no no DET ghmj-113 113 15 conflict conflict NOUN ghmj-113 113 16 of of ADP ghmj-113 113 17 interests interest NOUN ghmj-113 113 18 . . PUNCT ghmj-113 114 1 references reference NOUN ghmj-113 114 2 1 1 NUM ghmj-113 114 3 . . PUNCT ghmj-113 114 4 tabatabaei tabatabaei PROPN ghmj-113 114 5 mirakabad mirakabad PROPN ghmj-113 114 6 fsn fsn PROPN ghmj-113 114 7 - - PUNCT ghmj-113 114 8 k k PROPN ghmj-113 114 9 , , PUNCT ghmj-113 114 10 kazem kazem PROPN ghmj-113 114 11 ; ; PUNCT ghmj-113 114 12 akbarzadeh akbarzadeh PROPN ghmj-113 114 13 , , PUNCT ghmj-113 114 14 abolfazl abolfazl ADJ ghmj-113 114 15 ; ; PUNCT ghmj-113 114 16 yamchi yamchi NOUN ghmj-113 114 17 , , PUNCT ghmj-113 114 18 mohammad mohammad PROPN ghmj-113 114 19 rahmati rahmati PROPN ghmj-113 114 20 ; ; PUNCT ghmj-113 114 21 milani milani PROPN ghmj-113 114 22 , , PUNCT ghmj-113 114 23 mortaza mortaza PROPN ghmj-113 114 24 ; ; PUNCT ghmj-113 114 25 zarghami zarghami NOUN ghmj-113 114 26 , , PUNCT ghmj-113 114 27 nosratollah nosratollah ADV ghmj-113 114 28 ; ; PUNCT ghmj-113 114 29 zeighamian zeighamian NUM ghmj-113 114 30 , , PUNCT ghmj-113 114 31 vahideh vahideh PROPN ghmj-113 114 32 ; ; PUNCT ghmj-113 114 33 rahimzadeh rahimzadeh ADJ ghmj-113 114 34 , , PUNCT ghmj-113 114 35 amirbahman amirbahman NOUN ghmj-113 114 36 ; ; PUNCT ghmj-113 114 37 alimohammadi alimohammadi NOUN ghmj-113 114 38 , , PUNCT ghmj-113 114 39 somayeh somayeh NOUN ghmj-113 114 40 ; ; PUNCT ghmj-113 114 41 hanifehpour hanifehpour VERB ghmj-113 114 42 , , PUNCT ghmj-113 114 43 younes youne NOUN ghmj-113 114 44 ; ; PUNCT ghmj-113 114 45 joo joo NOUN ghmj-113 114 46 , , PUNCT ghmj-113 114 47 sang sing VERB ghmj-113 114 48 woo woo NOUN ghmj-113 114 49 . . PUNCT ghmj-113 115 1 plga plga NOUN ghmj-113 115 2 - - PUNCT ghmj-113 115 3 based base VERB ghmj-113 115 4 nanoparticles nanoparticle NOUN ghmj-113 115 5 as as ADP ghmj-113 115 6 cancer cancer NOUN ghmj-113 115 7 drug drug NOUN ghmj-113 115 8 delivery delivery NOUN ghmj-113 115 9 systems system NOUN ghmj-113 115 10 . . PUNCT ghmj-113 116 1 asian asian PROPN ghmj-113 116 2 pacific pacific PROPN ghmj-113 116 3 journal journal PROPN ghmj-113 116 4 of of ADP ghmj-113 116 5 cancer cancer NOUN ghmj-113 116 6 prevention prevention NOUN ghmj-113 116 7 . . PUNCT ghmj-113 117 1 2014;15(2):517 2014;15(2):517 NUM ghmj-113 117 2 - - SYM ghmj-113 117 3 35 35 NUM ghmj-113 117 4 . . PUNCT ghmj-113 118 1 2 2 NUM ghmj-113 118 2 . . X ghmj-113 118 3 dinarvand dinarvand NOUN ghmj-113 118 4 r r NOUN ghmj-113 118 5 , , PUNCT ghmj-113 118 6 sepehri sepehri NOUN ghmj-113 118 7 n n PRON ghmj-113 118 8 , , PUNCT ghmj-113 118 9 manoochehri manoochehri PROPN ghmj-113 118 10 s s PROPN ghmj-113 118 11 , , PUNCT ghmj-113 118 12 rouhani rouhani ADJ ghmj-113 118 13 h h NOUN ghmj-113 118 14 , , PUNCT ghmj-113 118 15 atyabi atyabi PROPN ghmj-113 118 16 f. f. PROPN ghmj-113 118 17 polylactide polylactide PROPN ghmj-113 118 18 - - PUNCT ghmj-113 118 19 co co ADJ ghmj-113 118 20 - - ADJ ghmj-113 118 21 glycolide glycolide ADJ ghmj-113 118 22 nanoparticles nanoparticle NOUN ghmj-113 118 23 for for ADP ghmj-113 118 24 controlled control VERB ghmj-113 118 25 delivery delivery NOUN ghmj-113 118 26 of of ADP ghmj-113 118 27 anticancer anticancer NOUN ghmj-113 118 28 agents agent NOUN ghmj-113 118 29 . . PUNCT ghmj-113 119 1 international international ADJ ghmj-113 119 2 journal journal PROPN ghmj-113 119 3 of of ADP ghmj-113 119 4 nanomedicine nanomedicine PROPN ghmj-113 119 5 . . PUNCT ghmj-113 120 1 2011;6:877 2011;6:877 NUM ghmj-113 120 2 - - SYM ghmj-113 120 3 95 95 NUM ghmj-113 120 4 . . PUNCT ghmj-113 121 1 3 3 X ghmj-113 121 2 . . X ghmj-113 121 3 marguet marguet PROPN ghmj-113 121 4 m m PROPN ghmj-113 121 5 , , PUNCT ghmj-113 121 6 bonduelle bonduelle PROPN ghmj-113 121 7 c c PROPN ghmj-113 121 8 , , PUNCT ghmj-113 121 9 lecommandoux lecommandoux PROPN ghmj-113 121 10 s. s. PROPN ghmj-113 121 11 multicompartmentalized multicompartmentalize VERB ghmj-113 121 12 polymeric polymeric ADJ ghmj-113 121 13 systems system NOUN ghmj-113 121 14 : : PUNCT ghmj-113 121 15 towards towards ADP ghmj-113 121 16 biomimetic biomimetic ADJ ghmj-113 121 17 cellular cellular ADJ ghmj-113 121 18 structure structure NOUN ghmj-113 121 19 and and CCONJ ghmj-113 121 20 function function NOUN ghmj-113 121 21 . . PUNCT ghmj-113 122 1 chemical chemical ADJ ghmj-113 122 2 society society NOUN ghmj-113 122 3 reviews review NOUN ghmj-113 122 4 . . PUNCT ghmj-113 123 1 2013;42(2):512 2013;42(2):512 NUM ghmj-113 123 2 - - SYM ghmj-113 123 3 29 29 NUM ghmj-113 123 4 . . PUNCT ghmj-113 124 1 4 4 NUM ghmj-113 124 2 . . X ghmj-113 125 1 kumari kumari PROPN ghmj-113 125 2 a a PROPN ghmj-113 125 3 , , PUNCT ghmj-113 125 4 yadav yadav PROPN ghmj-113 125 5 sk sk PROPN ghmj-113 125 6 , , PUNCT ghmj-113 125 7 yadav yadav PROPN ghmj-113 125 8 sc sc PROPN ghmj-113 125 9 . . PUNCT ghmj-113 125 10 biodegradable biodegradable ADJ ghmj-113 125 11 polymeric polymeric ADJ ghmj-113 125 12 nanoparticles nanoparticle NOUN ghmj-113 125 13 based base VERB ghmj-113 125 14 drug drug NOUN ghmj-113 125 15 delivery delivery NOUN ghmj-113 125 16 systems system NOUN ghmj-113 125 17 . . PUNCT ghmj-113 126 1 colloids colloid NOUN ghmj-113 126 2 and and CCONJ ghmj-113 126 3 surfaces surface NOUN ghmj-113 126 4 b b X ghmj-113 126 5 : : PUNCT ghmj-113 126 6 biointerfaces biointerface NOUN ghmj-113 126 7 . . PUNCT ghmj-113 127 1 2010;75(1):1 2010;75(1):1 NUM ghmj-113 127 2 - - SYM ghmj-113 127 3 18 18 NUM ghmj-113 127 4 . . NOUN ghmj-113 127 5 5 5 NUM ghmj-113 127 6 . . X ghmj-113 127 7 kocbek kocbek PROPN ghmj-113 128 1 p p PROPN ghmj-113 128 2 , , PUNCT ghmj-113 128 3 obermajer obermajer NOUN ghmj-113 128 4 n n CCONJ ghmj-113 128 5 , , PUNCT ghmj-113 128 6 cegnar cegnar PROPN ghmj-113 128 7 m m PROPN ghmj-113 128 8 , , PUNCT ghmj-113 128 9 kos kos PROPN ghmj-113 128 10 j j PROPN ghmj-113 128 11 , , PUNCT ghmj-113 128 12 kristl kristl PROPN ghmj-113 128 13 j. j. PROPN ghmj-113 128 14 targeting target VERB ghmj-113 128 15 cancer cancer NOUN ghmj-113 128 16 cells cell NOUN ghmj-113 128 17 using use VERB ghmj-113 128 18 plga plga NOUN ghmj-113 128 19 nanoparticles nanoparticle NOUN ghmj-113 128 20 surface surface VERB ghmj-113 128 21 modified modify VERB ghmj-113 128 22 with with ADP ghmj-113 128 23 monoclonal monoclonal NOUN ghmj-113 128 24 antibody antibody NOUN ghmj-113 128 25 . . PUNCT ghmj-113 129 1 journal journal NOUN ghmj-113 129 2 of of ADP ghmj-113 129 3 controlled control VERB ghmj-113 129 4 release release NOUN ghmj-113 129 5 . . PUNCT ghmj-113 130 1 2007;120(1):18 2007;120(1):18 NUM ghmj-113 130 2 - - PUNCT ghmj-113 130 3 26 26 NUM ghmj-113 130 4 . . NOUN ghmj-113 131 1 6 6 NUM ghmj-113 131 2 . . X ghmj-113 131 3 yin yin PROPN ghmj-113 131 4 win win PROPN ghmj-113 131 5 k k PROPN ghmj-113 131 6 , , PUNCT ghmj-113 131 7 feng feng PROPN ghmj-113 131 8 s s PROPN ghmj-113 131 9 - - PUNCT ghmj-113 131 10 s. s. PROPN ghmj-113 131 11 effects effect NOUN ghmj-113 131 12 of of ADP ghmj-113 131 13 particle particle NOUN ghmj-113 131 14 size size NOUN ghmj-113 131 15 and and CCONJ ghmj-113 131 16 surface surface NOUN ghmj-113 131 17 coating coating NOUN ghmj-113 131 18 on on ADP ghmj-113 131 19 cellular cellular ADJ ghmj-113 131 20 uptake uptake NOUN ghmj-113 131 21 of of ADP ghmj-113 131 22 polymeric polymeric ADJ ghmj-113 131 23 nanoparticles nanoparticle NOUN ghmj-113 131 24 for for ADP ghmj-113 131 25 oral oral ADJ ghmj-113 131 26 delivery delivery NOUN ghmj-113 131 27 of of ADP ghmj-113 131 28 anticancer anticancer NOUN ghmj-113 131 29 drugs drug NOUN ghmj-113 131 30 . . PUNCT ghmj-113 132 1 biomaterials biomaterial NOUN ghmj-113 132 2 . . PUNCT ghmj-113 133 1 2005;26(15):2713 2005;26(15):2713 NUM ghmj-113 133 2 - - SYM ghmj-113 133 3 22 22 NUM ghmj-113 133 4 . . PUNCT ghmj-113 134 1 7 7 X ghmj-113 134 2 . . X ghmj-113 134 3 zhou zhou PROPN ghmj-113 134 4 s s PROPN ghmj-113 134 5 , , PUNCT ghmj-113 134 6 deng deng PROPN ghmj-113 134 7 x x PROPN ghmj-113 134 8 , , PUNCT ghmj-113 134 9 li li PROPN ghmj-113 134 10 x x PROPN ghmj-113 134 11 , , PUNCT ghmj-113 134 12 jia jia PROPN ghmj-113 134 13 w w PROPN ghmj-113 134 14 , , PUNCT ghmj-113 134 15 liu liu PROPN ghmj-113 134 16 l. l. PROPN ghmj-113 134 17 synthesis synthesis NOUN ghmj-113 134 18 and and CCONJ ghmj-113 134 19 characterization characterization NOUN ghmj-113 134 20 of of ADP ghmj-113 134 21 biodegradable biodegradable ADJ ghmj-113 134 22 low low ADJ ghmj-113 134 23 molecular molecular ADJ ghmj-113 134 24 weight weight NOUN ghmj-113 134 25 aliphatic aliphatic ADJ ghmj-113 134 26 polyesters polyester NOUN ghmj-113 134 27 and and CCONJ ghmj-113 134 28 their their PRON ghmj-113 134 29 use use NOUN ghmj-113 134 30 in in ADP ghmj-113 134 31 proteindelivery proteindelivery NOUN ghmj-113 134 32 systems system NOUN ghmj-113 134 33 . . PUNCT ghmj-113 135 1 journal journal NOUN ghmj-113 135 2 of of ADP ghmj-113 135 3 applied apply VERB ghmj-113 135 4 polymer polymer NOUN ghmj-113 135 5 science science NOUN ghmj-113 135 6 . . PUNCT ghmj-113 136 1 2004;91(3):1848 2004;91(3):1848 NUM ghmj-113 136 2 - - SYM ghmj-113 136 3 56 56 NUM ghmj-113 136 4 . . NOUN ghmj-113 136 5 8 8 NUM ghmj-113 136 6 . . PUNCT ghmj-113 137 1 danhier danhier ADV ghmj-113 137 2 f f NOUN ghmj-113 137 3 , , PUNCT ghmj-113 137 4 ansorena ansorena NOUN ghmj-113 137 5 e e NOUN ghmj-113 137 6 , , PUNCT ghmj-113 137 7 silva silva PROPN ghmj-113 137 8 jm jm PROPN ghmj-113 137 9 , , PUNCT ghmj-113 137 10 coco coco PROPN ghmj-113 137 11 r r PROPN ghmj-113 137 12 , , PUNCT ghmj-113 137 13 le le X ghmj-113 137 14 breton breton PROPN ghmj-113 137 15 a a PROPN ghmj-113 137 16 , , PUNCT ghmj-113 137 17 préat préat NOUN ghmj-113 137 18 v. v. ADP ghmj-113 137 19 plga plga NOUN ghmj-113 137 20 - - PUNCT ghmj-113 137 21 based base VERB ghmj-113 137 22 nanoparticles nanoparticle NOUN ghmj-113 137 23 : : PUNCT ghmj-113 137 24 an an DET ghmj-113 137 25 overview overview NOUN ghmj-113 137 26 of of ADP ghmj-113 137 27 biomedical biomedical ADJ ghmj-113 137 28 applications application NOUN ghmj-113 137 29 . . PUNCT ghmj-113 138 1 journal journal PROPN ghmj-113 138 2 of of ADP ghmj-113 138 3 controlled control VERB ghmj-113 138 4 release release NOUN ghmj-113 138 5 . . PUNCT ghmj-113 139 1 2012;161(2):505 2012;161(2):505 PROPN ghmj-113 139 2 - - SYM ghmj-113 139 3 22 22 NUM ghmj-113 139 4 . . PUNCT ghmj-113 140 1 9 9 X ghmj-113 140 2 . . X ghmj-113 140 3 lü lü PROPN ghmj-113 140 4 j j PROPN ghmj-113 140 5 - - PROPN ghmj-113 140 6 m m PROPN ghmj-113 140 7 , , PUNCT ghmj-113 140 8 wang wang PROPN ghmj-113 140 9 x x PROPN ghmj-113 140 10 , , PUNCT ghmj-113 140 11 marin marin NOUN ghmj-113 140 12 - - PUNCT ghmj-113 140 13 muller muller NOUN ghmj-113 140 14 c c PROPN ghmj-113 140 15 , , PUNCT ghmj-113 140 16 wang wang PROPN ghmj-113 140 17 h h PROPN ghmj-113 140 18 , , PUNCT ghmj-113 140 19 lin lin PROPN ghmj-113 140 20 ph ph PROPN ghmj-113 140 21 , , PUNCT ghmj-113 140 22 yao yao PROPN ghmj-113 141 1 q q NOUN ghmj-113 141 2 , , PUNCT ghmj-113 141 3 et et PROPN ghmj-113 141 4 al al PROPN ghmj-113 141 5 . . PUNCT ghmj-113 142 1 current current ADJ ghmj-113 142 2 advances advance NOUN ghmj-113 142 3 in in ADP ghmj-113 142 4 research research NOUN ghmj-113 142 5 and and CCONJ ghmj-113 142 6 clinical clinical ADJ ghmj-113 142 7 applications application NOUN ghmj-113 142 8 of of ADP ghmj-113 142 9 plga plga NOUN ghmj-113 142 10 - - PUNCT ghmj-113 142 11 based base VERB ghmj-113 142 12 nanotechnology nanotechnology NOUN ghmj-113 142 13 . . PUNCT ghmj-113 143 1 expert expert NOUN ghmj-113 143 2 review review NOUN ghmj-113 143 3 of of ADP ghmj-113 143 4 molecular molecular ADJ ghmj-113 143 5 diagnostics diagnostic NOUN ghmj-113 143 6 . . PUNCT ghmj-113 144 1 2009;9(4):325 2009;9(4):325 NUM ghmj-113 144 2 - - SYM ghmj-113 144 3 41 41 NUM ghmj-113 144 4 . . PUNCT ghmj-113 145 1 10 10 NUM ghmj-113 145 2 . . PUNCT ghmj-113 145 3 alexis alexis PROPN ghmj-113 145 4 f f PROPN ghmj-113 145 5 , , PUNCT ghmj-113 145 6 pridgen pridgen PROPN ghmj-113 145 7 e e PROPN ghmj-113 145 8 , , PUNCT ghmj-113 145 9 molnar molnar PROPN ghmj-113 145 10 lk lk PROPN ghmj-113 145 11 , , PUNCT ghmj-113 145 12 farokhzad farokhzad ADJ ghmj-113 145 13 oc oc PROPN ghmj-113 145 14 . . PUNCT ghmj-113 146 1 factors factor NOUN ghmj-113 146 2 affecting affect VERB ghmj-113 146 3 the the DET ghmj-113 146 4 clearance clearance NOUN ghmj-113 146 5 and and CCONJ ghmj-113 146 6 biodistribution biodistribution NOUN ghmj-113 146 7 of of ADP ghmj-113 146 8 polymeric polymeric ADJ ghmj-113 146 9 nanoparticles nanoparticle NOUN ghmj-113 146 10 . . PUNCT ghmj-113 147 1 molecular molecular ADJ ghmj-113 147 2 pharmaceutics pharmaceutic NOUN ghmj-113 147 3 . . PUNCT ghmj-113 148 1 2008;5(4):505 2008;5(4):505 NUM ghmj-113 148 2 - - SYM ghmj-113 148 3 15 15 NUM ghmj-113 148 4 . . PUNCT ghmj-113 149 1 11 11 NUM ghmj-113 149 2 . . PUNCT ghmj-113 150 1 singh singh PROPN ghmj-113 150 2 r r PROPN ghmj-113 150 3 , , PUNCT ghmj-113 150 4 lillard lillard PROPN ghmj-113 150 5 jw jw PROPN ghmj-113 150 6 . . PROPN ghmj-113 150 7 nanoparticle nanoparticle PROPN ghmj-113 150 8 - - PUNCT ghmj-113 150 9 based base VERB ghmj-113 150 10 targeted target VERB ghmj-113 150 11 drug drug NOUN ghmj-113 150 12 delivery delivery NOUN ghmj-113 150 13 . . PUNCT ghmj-113 151 1 experimental experimental ADJ ghmj-113 151 2 and and CCONJ ghmj-113 151 3 molecular molecular ADJ ghmj-113 151 4 pathology pathology NOUN ghmj-113 151 5 . . PUNCT ghmj-113 152 1 2009;86(3):215 2009;86(3):215 PROPN ghmj-113 152 2 - - PUNCT ghmj-113 152 3 23 23 NUM ghmj-113 152 4 . . PUNCT ghmj-113 152 5 12 12 NUM ghmj-113 152 6 . . PUNCT ghmj-113 153 1 redhead redhead PROPN ghmj-113 153 2 hm hm PROPN ghmj-113 153 3 , , PUNCT ghmj-113 153 4 davis davis PROPN ghmj-113 153 5 ss ss PROPN ghmj-113 153 6 , , PUNCT ghmj-113 153 7 illum illum PROPN ghmj-113 153 8 l. l. PROPN ghmj-113 153 9 drug drug PROPN ghmj-113 153 10 delivery delivery NOUN ghmj-113 153 11 in in ADP ghmj-113 153 12 poly(lactide poly(lactide PROPN ghmj-113 153 13 - - PUNCT ghmj-113 153 14 co co NOUN ghmj-113 153 15 - - ADJ ghmj-113 153 16 glycolide glycolide ADJ ghmj-113 153 17 ) ) PUNCT ghmj-113 153 18 nanoparticles nanoparticle NOUN ghmj-113 153 19 surface surface VERB ghmj-113 153 20 modified modify VERB ghmj-113 153 21 with with ADP ghmj-113 153 22 poloxamer poloxamer PROPN ghmj-113 153 23 407 407 NUM ghmj-113 153 24 and and CCONJ ghmj-113 153 25 poloxamine poloxamine VERB ghmj-113 153 26 908 908 NUM ghmj-113 153 27 : : PUNCT ghmj-113 153 28 in in ADP ghmj-113 153 29 vitro vitro X ghmj-113 153 30 characterisation characterisation NOUN ghmj-113 153 31 and and CCONJ ghmj-113 153 32 in in ADP ghmj-113 153 33 vivo vivo ADJ ghmj-113 153 34 evaluation evaluation NOUN ghmj-113 153 35 . . PUNCT ghmj-113 154 1 journal journal PROPN ghmj-113 154 2 of of ADP ghmj-113 154 3 controlled control VERB ghmj-113 154 4 release release NOUN ghmj-113 154 5 . . PUNCT ghmj-113 155 1 2001;70(3):353 2001;70(3):353 NUM ghmj-113 155 2 - - SYM ghmj-113 155 3 63 63 NUM ghmj-113 155 4 . . PUNCT ghmj-113 155 5 13 13 NUM ghmj-113 155 6 . . PUNCT ghmj-113 156 1 panyam panyam PROPN ghmj-113 156 2 j j PROPN ghmj-113 156 3 , , PUNCT ghmj-113 156 4 dali dali PROPN ghmj-113 156 5 mm mm PROPN ghmj-113 156 6 , , PUNCT ghmj-113 156 7 sahoo sahoo PROPN ghmj-113 156 8 sk sk PROPN ghmj-113 156 9 , , PUNCT ghmj-113 156 10 ma ma PROPN ghmj-113 156 11 w w PROPN ghmj-113 156 12 , , PUNCT ghmj-113 156 13 chakravarthi chakravarthi PROPN ghmj-113 156 14 ss ss PROPN ghmj-113 156 15 , , PUNCT ghmj-113 156 16 amidon amidon PROPN ghmj-113 156 17 gl gl PROPN ghmj-113 156 18 , , PUNCT ghmj-113 156 19 et et PROPN ghmj-113 156 20 al al PROPN ghmj-113 156 21 . . PUNCT ghmj-113 156 22 polymer polymer NOUN ghmj-113 156 23 degradation degradation NOUN ghmj-113 156 24 and and CCONJ ghmj-113 156 25 in in ADP ghmj-113 156 26 vitro vitro X ghmj-113 156 27 release release NOUN ghmj-113 156 28 of of ADP ghmj-113 156 29 a a DET ghmj-113 156 30 model model NOUN ghmj-113 156 31 protein protein NOUN ghmj-113 156 32 from from ADP ghmj-113 156 33 poly(d poly(d NOUN ghmj-113 156 34 , , PUNCT ghmj-113 156 35 l l NOUN ghmj-113 156 36 - - ADJ ghmj-113 156 37 lactideco lactideco ADJ ghmj-113 156 38 - - PUNCT ghmj-113 156 39 glycolide glycolide NOUN ghmj-113 156 40 ) ) PUNCT ghmj-113 156 41 nanoand nanoand NOUN ghmj-113 156 42 microparticles microparticle NOUN ghmj-113 156 43 . . PUNCT ghmj-113 157 1 journal journal PROPN ghmj-113 157 2 of of ADP ghmj-113 157 3 controlled control VERB ghmj-113 157 4 release release NOUN ghmj-113 157 5 . . PUNCT ghmj-113 158 1 2003;92(1):173 2003;92(1):173 NUM ghmj-113 158 2 - - SYM ghmj-113 158 3 87 87 NUM ghmj-113 158 4 . . PUNCT ghmj-113 159 1 14 14 NUM ghmj-113 159 2 . . PUNCT ghmj-113 160 1 choi choi PROPN ghmj-113 160 2 hs hs PROPN ghmj-113 160 3 , , PUNCT ghmj-113 160 4 liu liu PROPN ghmj-113 160 5 w w PROPN ghmj-113 160 6 , , PUNCT ghmj-113 160 7 misra misra NOUN ghmj-113 160 8 p p X ghmj-113 160 9 , , PUNCT ghmj-113 160 10 tanaka tanaka PROPN ghmj-113 160 11 e e PROPN ghmj-113 160 12 , , PUNCT ghmj-113 160 13 zimmer zimmer PROPN ghmj-113 160 14 jp jp PROPN ghmj-113 160 15 , , PUNCT ghmj-113 160 16 ipe ipe NOUN ghmj-113 160 17 bi bi NOUN ghmj-113 160 18 , , PUNCT ghmj-113 160 19 et et PROPN ghmj-113 160 20 al al PROPN ghmj-113 160 21 . . PUNCT ghmj-113 161 1 renal renal ADJ ghmj-113 161 2 clearance clearance NOUN ghmj-113 161 3 of of ADP ghmj-113 161 4 nanoparticles nanoparticle NOUN ghmj-113 161 5 . . PUNCT ghmj-113 162 1 nature nature NOUN ghmj-113 162 2 biotechnology biotechnology NOUN ghmj-113 162 3 . . PUNCT ghmj-113 163 1 2007;25(10):1165 2007;25(10):1165 NUM ghmj-113 163 2 - - SYM ghmj-113 163 3 70 70 NUM ghmj-113 163 4 . . PUNCT ghmj-113 164 1 15 15 NUM ghmj-113 164 2 . . PUNCT ghmj-113 165 1 montalvo montalvo PROPN ghmj-113 165 2 - - PUNCT ghmj-113 165 3 ortiz ortiz PROPN ghmj-113 165 4 bl bl PROPN ghmj-113 165 5 , , PUNCT ghmj-113 165 6 sosa sosa PROPN ghmj-113 165 7 b b PROPN ghmj-113 165 8 , , PUNCT ghmj-113 165 9 griebenow griebenow PROPN ghmj-113 165 10 k. k. PROPN ghmj-113 165 11 improved improve VERB ghmj-113 165 12 enzyme enzyme NOUN ghmj-113 165 13 activity activity NOUN ghmj-113 165 14 and and CCONJ ghmj-113 165 15 stability stability NOUN ghmj-113 165 16 in in ADP ghmj-113 165 17 polymer polymer NOUN ghmj-113 165 18 microspheres microsphere NOUN ghmj-113 165 19 by by ADP ghmj-113 165 20 encapsulation encapsulation NOUN ghmj-113 165 21 of of ADP ghmj-113 165 22 protein protein NOUN ghmj-113 165 23 nanospheres nanosphere NOUN ghmj-113 165 24 . . PUNCT ghmj-113 166 1 aaps aap NOUN ghmj-113 166 2 pharmscitech pharmscitech VERB ghmj-113 166 3 . . PUNCT ghmj-113 167 1 2012;13(2):632 2012;13(2):632 NUM ghmj-113 167 2 - - PUNCT ghmj-113 167 3 6 6 NUM ghmj-113 167 4 . . NOUN ghmj-113 167 5 16 16 NUM ghmj-113 167 6 . . PUNCT ghmj-113 168 1 morales morales PROPN ghmj-113 168 2 - - PUNCT ghmj-113 168 3 cruz cruz PROPN ghmj-113 168 4 m m PROPN ghmj-113 168 5 , , PUNCT ghmj-113 168 6 flores flores PROPN ghmj-113 168 7 - - PUNCT ghmj-113 168 8 fernández fernández PROPN ghmj-113 168 9 gm gm PROPN ghmj-113 168 10 , , PUNCT ghmj-113 168 11 moralescruz moralescruz PROPN ghmj-113 168 12 m m PROPN ghmj-113 168 13 , , PUNCT ghmj-113 168 14 orellano orellano PROPN ghmj-113 168 15 ea ea PROPN ghmj-113 168 16 , , PUNCT ghmj-113 168 17 rodriguez rodriguez PROPN ghmj-113 168 18 - - PUNCT ghmj-113 168 19 martinez martinez PROPN ghmj-113 168 20 ja ja PROPN ghmj-113 168 21 , , PUNCT ghmj-113 168 22 ruiz ruiz NOUN ghmj-113 168 23 m m PROPN ghmj-113 168 24 , , PUNCT ghmj-113 168 25 et et PROPN ghmj-113 168 26 al al PROPN ghmj-113 168 27 . . PROPN ghmj-113 169 1 two two NUM ghmj-113 169 2 - - PUNCT ghmj-113 169 3 step step NOUN ghmj-113 169 4 nanoprecipitation nanoprecipitation NOUN ghmj-113 169 5 for for ADP ghmj-113 169 6 the the DET ghmj-113 169 7 production production NOUN ghmj-113 169 8 of of ADP ghmj-113 169 9 protein protein NOUN ghmj-113 169 10 - - PUNCT ghmj-113 169 11 loaded load VERB ghmj-113 169 12 plga plga NOUN ghmj-113 169 13 nanospheres nanosphere NOUN ghmj-113 169 14 . . PUNCT ghmj-113 170 1 results result NOUN ghmj-113 170 2 in in ADP ghmj-113 170 3 pharma pharma PROPN ghmj-113 170 4 sciences science NOUN ghmj-113 170 5 . . PUNCT ghmj-113 171 1 2012;2:79 2012;2:79 NOUN ghmj-113 171 2 - - PUNCT ghmj-113 171 3 85 85 NUM ghmj-113 171 4 . . PUNCT ghmj-113 171 5 17 17 NUM ghmj-113 171 6 . . PUNCT ghmj-113 171 7 mittal mittal PROPN ghmj-113 171 8 g g PROPN ghmj-113 171 9 , , PUNCT ghmj-113 171 10 sahana sahana PROPN ghmj-113 171 11 dk dk PROPN ghmj-113 171 12 , , PUNCT ghmj-113 171 13 bhardwaj bhardwaj PROPN ghmj-113 171 14 v v PROPN ghmj-113 171 15 , , PUNCT ghmj-113 171 16 ravi ravi PROPN ghmj-113 171 17 kumar kumar PROPN ghmj-113 171 18 mnv mnv PROPN ghmj-113 171 19 . . PUNCT ghmj-113 172 1 estradiol estradiol PROPN ghmj-113 172 2 loaded load VERB ghmj-113 172 3 plga plga NOUN ghmj-113 172 4 nanoparticles nanoparticle NOUN ghmj-113 172 5 for for ADP ghmj-113 172 6 oral oral ADJ ghmj-113 172 7 administration administration NOUN ghmj-113 172 8 : : PUNCT ghmj-113 172 9 effect effect NOUN ghmj-113 172 10 of of ADP ghmj-113 172 11 polymer polymer NOUN ghmj-113 172 12 molecular molecular ADJ ghmj-113 172 13 weight weight NOUN ghmj-113 172 14 and and CCONJ ghmj-113 172 15 copolymer copolymer NOUN ghmj-113 172 16 composition composition NOUN ghmj-113 172 17 on on ADP ghmj-113 172 18 release release NOUN ghmj-113 172 19 behavior behavior NOUN ghmj-113 172 20 in in ADP ghmj-113 172 21 vitro vitro X ghmj-113 172 22 and and CCONJ ghmj-113 172 23 in in ADP ghmj-113 172 24 vivo vivo NOUN ghmj-113 172 25 . . PUNCT ghmj-113 173 1 journal journal PROPN ghmj-113 173 2 of of ADP ghmj-113 173 3 controlled control VERB ghmj-113 173 4 release release NOUN ghmj-113 173 5 . . PUNCT ghmj-113 174 1 2007;119(1):77 2007;119(1):77 NUM ghmj-113 174 2 - - PUNCT ghmj-113 174 3 85 85 NUM ghmj-113 174 4 . . PUNCT ghmj-113 174 5 18 18 NUM ghmj-113 174 6 . . PUNCT ghmj-113 175 1 dutschk dutschk PROPN ghmj-113 175 2 v v PROPN ghmj-113 175 3 , , PUNCT ghmj-113 175 4 chen chen PROPN ghmj-113 175 5 j j PROPN ghmj-113 175 6 , , PUNCT ghmj-113 175 7 petzold petzold VERB ghmj-113 175 8 g g PROPN ghmj-113 175 9 , , PUNCT ghmj-113 175 10 vogel vogel NOUN ghmj-113 175 11 r r PROPN ghmj-113 175 12 , , PUNCT ghmj-113 175 13 clausse clausse NOUN ghmj-113 175 14 d d PROPN ghmj-113 175 15 , , PUNCT ghmj-113 175 16 ravera ravera PROPN ghmj-113 175 17 f f PROPN ghmj-113 175 18 , , PUNCT ghmj-113 175 19 et et PROPN ghmj-113 175 20 al al PROPN ghmj-113 175 21 . . PUNCT ghmj-113 176 1 the the DET ghmj-113 176 2 role role NOUN ghmj-113 176 3 of of ADP ghmj-113 176 4 emulsifier emulsifier NOUN ghmj-113 176 5 in in ADP ghmj-113 176 6 stabilization stabilization NOUN ghmj-113 176 7 of of ADP ghmj-113 176 8 emulsions emulsion NOUN ghmj-113 176 9 containing contain VERB ghmj-113 176 10 colloidal colloidal NOUN ghmj-113 176 11 alumina alumina NOUN ghmj-113 176 12 particles particle NOUN ghmj-113 176 13 . . PUNCT ghmj-113 177 1 colloids colloid NOUN ghmj-113 177 2 and and CCONJ ghmj-113 177 3 surfaces surface NOUN ghmj-113 177 4 a a DET ghmj-113 177 5 : : PUNCT ghmj-113 177 6 physicochemical physicochemical ADJ ghmj-113 177 7 and and CCONJ ghmj-113 177 8 engineering engineering NOUN ghmj-113 177 9 aspects aspect NOUN ghmj-113 177 10 . . PUNCT ghmj-113 178 1 2012;413(supplement 2012;413(supplement NUM ghmj-113 178 2 c):23947 c):23947 X ghmj-113 178 3 . . PUNCT ghmj-113 179 1 19 19 NUM ghmj-113 179 2 . . PUNCT ghmj-113 180 1 sahoo sahoo PROPN ghmj-113 180 2 sk sk PROPN ghmj-113 180 3 , , PUNCT ghmj-113 180 4 panyam panyam PROPN ghmj-113 180 5 j j PROPN ghmj-113 180 6 , , PUNCT ghmj-113 180 7 prabha prabha NOUN ghmj-113 180 8 s s PART ghmj-113 180 9 , , PUNCT ghmj-113 180 10 labhasetwar labhasetwar ADV ghmj-113 180 11 v. v. ADP ghmj-113 180 12 residual residual ADJ ghmj-113 180 13 polyvinyl polyvinyl NOUN ghmj-113 180 14 alcohol alcohol NOUN ghmj-113 180 15 associated associate VERB ghmj-113 180 16 with with ADP ghmj-113 180 17 poly poly ADJ ghmj-113 180 18 ( ( PUNCT ghmj-113 180 19 d d NOUN ghmj-113 180 20 , , PUNCT ghmj-113 180 21 llactide llactide NOUN ghmj-113 180 22 - - PUNCT ghmj-113 180 23 co co NOUN ghmj-113 180 24 - - ADJ ghmj-113 180 25 glycolide glycolide ADJ ghmj-113 180 26 ) ) PUNCT ghmj-113 180 27 nanoparticles nanoparticle NOUN ghmj-113 180 28 affects affect VERB ghmj-113 180 29 their their PRON ghmj-113 180 30 physical physical ADJ ghmj-113 180 31 properties property NOUN ghmj-113 180 32 and and CCONJ ghmj-113 180 33 cellular cellular ADJ ghmj-113 180 34 uptake uptake NOUN ghmj-113 180 35 . . PUNCT ghmj-113 181 1 journal journal PROPN ghmj-113 181 2 of of ADP ghmj-113 181 3 controlled control VERB ghmj-113 181 4 release release NOUN ghmj-113 181 5 . . PUNCT ghmj-113 182 1 2002;82(1):105 2002;82(1):105 NUM ghmj-113 182 2 - - SYM ghmj-113 182 3 14 14 NUM ghmj-113 182 4 . . PUNCT ghmj-113 183 1 20 20 NUM ghmj-113 183 2 . . PUNCT ghmj-113 183 3 mccall mccall PROPN ghmj-113 183 4 rl rl PROPN ghmj-113 183 5 , , PUNCT ghmj-113 183 6 sirianni sirianni PROPN ghmj-113 183 7 rw rw PROPN ghmj-113 183 8 . . PUNCT ghmj-113 183 9 plga plga NOUN ghmj-113 183 10 nanoparticles nanoparticle NOUN ghmj-113 183 11 formed form VERB ghmj-113 183 12 by by ADP ghmj-113 183 13 singleor singleor NOUN ghmj-113 183 14 double double ADJ ghmj-113 183 15 - - PUNCT ghmj-113 183 16 emulsion emulsion NOUN ghmj-113 183 17 with with ADP ghmj-113 183 18 vitamin vitamin NOUN ghmj-113 183 19 e e NOUN ghmj-113 183 20 - - NOUN ghmj-113 183 21 tpgs tpgs ADJ ghmj-113 183 22 . . PUNCT ghmj-113 184 1 journal journal NOUN ghmj-113 184 2 of of ADP ghmj-113 184 3 visualized visualized ADJ ghmj-113 184 4 experiments experiment NOUN ghmj-113 184 5 : : PUNCT ghmj-113 184 6 jove jove NOUN ghmj-113 184 7 . . PUNCT ghmj-113 185 1 2013(82):51015 2013(82):51015 NUM ghmj-113 185 2 . . PUNCT ghmj-113 186 1 21 21 NUM ghmj-113 186 2 . . PUNCT ghmj-113 186 3 bilati bilati PROPN ghmj-113 186 4 u u NOUN ghmj-113 186 5 , , PUNCT ghmj-113 186 6 allémann allémann PROPN ghmj-113 186 7 e e NOUN ghmj-113 186 8 , , PUNCT ghmj-113 186 9 doelker doelker PROPN ghmj-113 186 10 e. e. PROPN ghmj-113 186 11 sonication sonication NOUN ghmj-113 186 12 parameters parameter NOUN ghmj-113 186 13 for for ADP ghmj-113 186 14 the the DET ghmj-113 186 15 preparation preparation NOUN ghmj-113 186 16 of of ADP ghmj-113 186 17 biodegradable biodegradable ADJ ghmj-113 186 18 nanocapsulesof nanocapsulesof NOUN ghmj-113 186 19 controlled control VERB ghmj-113 186 20 size size NOUN ghmj-113 186 21 by by ADP ghmj-113 186 22 the the DET ghmj-113 186 23 double double ADJ ghmj-113 186 24 emulsion emulsion NOUN ghmj-113 186 25 method method NOUN ghmj-113 186 26 . . PUNCT ghmj-113 187 1 pharmaceutical pharmaceutical NOUN ghmj-113 187 2 development development NOUN ghmj-113 187 3 and and CCONJ ghmj-113 187 4 technology technology NOUN ghmj-113 187 5 . . PUNCT ghmj-113 188 1 2003;8(1):1 2003;8(1):1 NOUN ghmj-113 188 2 - - PUNCT ghmj-113 188 3 9 9 NUM ghmj-113 188 4 . . PUNCT