id	sid	tid	token	lemma	pos
gra-2157	1	1	14.bluetree	14.bluetree	X
gra-2157	1	2	01.cdr	01.cdr	PROPN
gra-2157	1	3	globally	globally	ADV
gra-2157	1	4	,	,	PUNCT
gra-2157	1	5	the	the	DET
gra-2157	1	6	prevalence	prevalence	NOUN
gra-2157	1	7	of	of	ADP
gra-2157	1	8	diabetes	diabetes	NOUN
gra-2157	1	9	mellitus	mellitus	NOUN
gra-2157	1	10	is	be	AUX
gra-2157	1	11	continuously	continuously	ADV
gra-2157	1	12	escalating	escalate	VERB
gra-2157	1	13	.	.	PUNCT
gra-2157	2	1	the	the	DET
gra-2157	2	2	complications	complication	NOUN
gra-2157	2	3	of	of	ADP
gra-2157	2	4	chronic	chronic	ADJ
gra-2157	2	5	diabetes	diabetes	NOUN
gra-2157	2	6	mellitus	mellitus	NOUN
gra-2157	2	7	i	i	PRON
gra-2157	2	8	n	n	VERB
gra-2157	2	9	c	c	NOUN
gra-2157	2	10	l	l	NOUN
gra-2157	3	1	u	u	X
gra-2157	4	1	d	d	X
gra-2157	4	2	e	e	X
gra-2157	4	3	r	r	NOUN
gra-2157	4	4	e	e	NOUN
gra-2157	4	5	t	t	NOUN
gra-2157	4	6	i	i	PRON
gra-2157	4	7	n	n	ADV
gra-2157	5	1	o	o	NOUN
gra-2157	5	2	p	p	X
gra-2157	5	3	a	a	DET
gra-2157	5	4	t	t	NOUN
gra-2157	5	5	h	h	NOUN
gra-2157	5	6	y	y	PROPN
gra-2157	5	7	,	,	PUNCT
gra-2157	5	8	n	n	PROPN
gra-2157	5	9	e	e	NOUN
gra-2157	5	10	u	u	NOUN
gra-2157	5	11	r	r	NOUN
gra-2157	5	12	o	o	NOUN
gra-2157	5	13	p	p	NOUN
gra-2157	5	14	a	a	DET
gra-2157	5	15	t	t	NOUN
gra-2157	5	16	h	h	NOUN
gra-2157	5	17	y	y	PROPN
gra-2157	5	18	,	,	PUNCT
gra-2157	5	19	n	n	PROPN
gra-2157	6	1	e	e	NOUN
gra-2157	6	2	p	p	NOUN
gra-2157	6	3	h	h	NOUN
gra-2157	6	4	r	r	NOUN
gra-2157	6	5	o	o	NOUN
gra-2157	6	6	p	p	NOUN
gra-2157	6	7	a	a	DET
gra-2157	6	8	t	t	NOUN
gra-2157	6	9	h	h	NOUN
gra-2157	6	10	y	y	NOUN
gra-2157	6	11	,	,	PUNCT
gra-2157	6	12	cardiomyopathy	cardiomyopathy	ADJ
gra-2157	6	13	,	,	PUNCT
gra-2157	6	14	and	and	CCONJ
gra-2157	6	15	vasculopathy	vasculopathy	NOUN
gra-2157	6	16	.	.	PUNCT
gra-2157	7	1	diabetes	diabetes	NOUN
gra-2157	7	2	mellitus	mellitus	NOUN
gra-2157	7	3	is	be	AUX
gra-2157	7	4	the	the	DET
gra-2157	7	5	leading	lead	VERB
gra-2157	7	6	cause	cause	NOUN
gra-2157	7	7	of	of	ADP
gra-2157	7	8	renal	renal	ADJ
gra-2157	7	9	failure	failure	NOUN
gra-2157	7	10	and	and	CCONJ
gra-2157	7	11	approximately	approximately	ADV
gra-2157	7	12	20	20	NUM
gra-2157	7	13	-	-	SYM
gra-2157	7	14	30	30	NUM
gra-2157	7	15	%	%	NOUN
gra-2157	7	16	of	of	ADP
gra-2157	7	17	all	all	DET
gra-2157	7	18	diabetic	diabetic	ADJ
gra-2157	7	19	subjects	subject	NOUN
gra-2157	7	20	develop	develop	VERB
gra-2157	7	21	evidence	evidence	NOUN
gra-2157	7	22	of	of	ADP
gra-2157	7	23	diabetic	diabetic	ADJ
gra-2157	7	24	nephropathy	nephropathy	NOUN
gra-2157	7	25	manifesting	manifest	VERB
gra-2157	7	26	from	from	ADP
gra-2157	7	27	microalbuminuria	microalbuminuria	PROPN
gra-2157	7	28	to	to	ADP
gra-2157	7	29	macroal	macroal	PROPN
gra-2157	7	30	buminuria	buminuria	PROPN
gra-2157	7	31	and	and	CCONJ
gra-2157	7	32	renal	renal	ADJ
gra-2157	7	33	failure	failure	NOUN
gra-2157	7	34	.	.	PUNCT
gra-2157	8	1	nephropathy	nephropathy	NOUN
gra-2157	8	2	is	be	AUX
gra-2157	8	3	one	one	NUM
gra-2157	8	4	of	of	ADP
gra-2157	8	5	the	the	DET
gra-2157	8	6	major	major	ADJ
gra-2157	8	7	complications	complication	NOUN
gra-2157	8	8	of	of	ADP
gra-2157	8	9	uncontrolled	uncontrolled	ADJ
gra-2157	8	10	diabetes	diabetes	NOUN
gra-2157	8	11	mellitus	mellitus	NOUN
gra-2157	8	12	.	.	PUNCT
gra-2157	9	1	the	the	DET
gra-2157	9	2	renal	renal	ADJ
gra-2157	9	3	pathologic	pathologic	ADJ
gra-2157	9	4	alterations	alteration	NOUN
gra-2157	9	5	of	of	ADP
gra-2157	9	6	diabetic	diabetic	ADJ
gra-2157	9	7	nephropathy	nephropathy	NOUN
gra-2157	9	8	are	be	AUX
gra-2157	9	9	associated	associate	VERB
gra-2157	9	10	with	with	ADP
gra-2157	9	11	glomerular	glomerular	ADJ
gra-2157	9	12	basement	basement	NOUN
gra-2157	9	13	membrane	membrane	NOUN
gra-2157	9	14	thickening	thickening	NOUN
gra-2157	9	15	,	,	PUNCT
gra-2157	9	16	mesangial	mesangial	ADJ
gra-2157	9	17	cell	cell	NOUN
gra-2157	9	18	expansion	expansion	NOUN
gra-2157	9	19	,	,	PUNCT
gra-2157	9	20	glomerulosclerosis	glomerulosclerosis	NOUN
gra-2157	9	21	,	,	PUNCT
gra-2157	9	22	interstitial	interstitial	ADJ
gra-2157	9	23	brosis	brosis	PROPN
gra-2157	9	24	,	,	PUNCT
gra-2157	9	25	podocyte	podocyte	NOUN
gra-2157	9	26	loss	loss	NOUN
gra-2157	9	27	,	,	PUNCT
gra-2157	9	28	and	and	CCONJ
gra-2157	9	29	tubular	tubular	ADJ
gra-2157	9	30	atrophy	atrophy	NOUN
gra-2157	9	31	.	.	PUNCT
gra-2157	10	1	these	these	DET
gra-2157	10	2	renal	renal	ADJ
gra-2157	10	3	alterations	alteration	NOUN
gra-2157	10	4	during	during	ADP
gra-2157	10	5	diabetic	diabetic	ADJ
gra-2157	10	6	nephropathy	nephropathy	NOUN
gra-2157	10	7	could	could	AUX
gra-2157	10	8	result	result	VERB
gra-2157	10	9	in	in	ADP
gra-2157	10	10	albuminuria	albuminuria	PROPN
gra-2157	10	11	,	,	PUNCT
gra-2157	10	12	a	a	DET
gra-2157	10	13	decrease	decrease	NOUN
gra-2157	10	14	in	in	ADP
gra-2157	10	15	glomerular	glomerular	ADJ
gra-2157	10	16	ltration	ltration	NOUN
gra-2157	10	17	rate	rate	NOUN
gra-2157	10	18	(	(	PUNCT
gra-2157	10	19	gfr	gfr	NOUN
gra-2157	10	20	)	)	PUNCT
gra-2157	10	21	and	and	CCONJ
gra-2157	10	22	an	an	DET
gra-2157	10	23	increase	increase	NOUN
gra-2157	10	24	1	1	NUM
gra-2157	10	25	in	in	ADP
gra-2157	10	26	serum	serum	NOUN
gra-2157	10	27	creatinine	creatinine	NOUN
gra-2157	10	28	and	and	CCONJ
gra-2157	10	29	urea	urea	PROPN
gra-2157	10	30	nitrogen	nitrogen	NOUN
gra-2157	10	31	levels	level	NOUN
gra-2157	10	32	.	.	PUNCT
gra-2157	11	1	the	the	DET
gra-2157	11	2	reninangiotensin	reninangiotensin	NOUN
gra-2157	11	3	system	system	NOUN
gra-2157	11	4	(	(	PUNCT
gra-2157	11	5	ras	ras	NOUN
gra-2157	11	6	)	)	PUNCT
gra-2157	11	7	plays	play	VERB
gra-2157	11	8	a	a	DET
gra-2157	11	9	pivotal	pivotal	ADJ
gra-2157	11	10	role	role	NOUN
gra-2157	11	11	in	in	ADP
gra-2157	11	12	the	the	DET
gra-2157	11	13	2pathogenesis	2pathogenesis	NUM
gra-2157	11	14	of	of	ADP
gra-2157	11	15	diabetic	diabetic	ADJ
gra-2157	11	16	nephropathy	nephropathy	NOUN
gra-2157	11	17	.	.	PUNCT
gra-2157	12	1	the	the	DET
gra-2157	12	2	activation	activation	NOUN
gra-2157	12	3	of	of	ADP
gra-2157	12	4	the	the	DET
gra-2157	12	5	renin	renin	ADJ
gra-2157	12	6	-	-	PUNCT
gra-2157	12	7	angiotensin	angiotensin	NOUN
gra-2157	12	8	system	system	NOUN
gra-2157	12	9	,	,	PUNCT
gra-2157	12	10	especially	especially	ADV
gra-2157	12	11	the	the	DET
gra-2157	12	12	angiotensin	angiotensin	NOUN
gra-2157	12	13	ii	ii	PROPN
gra-2157	12	14	type-1	type-1	PROPN
gra-2157	12	15	receptor	receptor	NOUN
gra-2157	12	16	(	(	PUNCT
gra-2157	12	17	at1r	at1r	NOUN
gra-2157	12	18	)	)	PUNCT
gra-2157	12	19	pathway	pathway	NOUN
gra-2157	12	20	,	,	PUNCT
gra-2157	12	21	has	have	AUX
gra-2157	12	22	been	be	AUX
gra-2157	12	23	demonstrated	demonstrate	VERB
gra-2157	12	24	to	to	PART
gra-2157	12	25	play	play	VERB
gra-2157	12	26	a	a	DET
gra-2157	12	27	3detrimental	3detrimental	NUM
gra-2157	12	28	role	role	NOUN
gra-2157	12	29	in	in	ADP
gra-2157	12	30	the	the	DET
gra-2157	12	31	progression	progression	NOUN
gra-2157	12	32	of	of	ADP
gra-2157	12	33	diabetic	diabetic	ADJ
gra-2157	12	34	nephropathy	nephropathy	NOUN
gra-2157	12	35	.	.	PUNCT
gra-2157	13	1	even	even	ADV
gra-2157	13	2	though	though	SCONJ
gra-2157	13	3	the	the	DET
gra-2157	13	4	etiology	etiology	NOUN
gra-2157	13	5	of	of	ADP
gra-2157	13	6	diabetic	diabetic	ADJ
gra-2157	13	7	nephropathy	nephropathy	NOUN
gra-2157	13	8	is	be	AUX
gra-2157	13	9	poorly	poorly	ADV
gra-2157	13	10	understood	understand	VERB
gra-2157	13	11	,	,	PUNCT
gra-2157	13	12	chronic	chronic	ADJ
gra-2157	13	13	hyperglycemia	hyperglycemia	NOUN
gra-2157	13	14	and	and	CCONJ
gra-2157	13	15	hypertension	hypertension	NOUN
gra-2157	13	16	are	be	AUX
gra-2157	13	17	1considered	1considered	NUM
gra-2157	13	18	major	major	ADJ
gra-2157	13	19	risk	risk	NOUN
gra-2157	13	20	factors	factor	NOUN
gra-2157	13	21	for	for	ADP
gra-2157	13	22	diabetic	diabetic	ADJ
gra-2157	13	23	nephropathy	nephropathy	NOUN
gra-2157	13	24	.	.	PUNCT
gra-2157	14	1	although	although	SCONJ
gra-2157	14	2	various	various	ADJ
gra-2157	14	3	hyperglycemia	hyperglycemia	NOUN
gra-2157	14	4	-	-	PUNCT
gra-2157	14	5	elicited	elicit	VERB
gra-2157	14	6	metabolic	metabolic	NOUN
gra-2157	14	7	derangements	derangement	NOUN
gra-2157	14	8	such	such	ADJ
gra-2157	14	9	as	as	ADP
gra-2157	14	10	the	the	DET
gra-2157	14	11	increased	increase	VERB
gra-2157	14	12	formation	formation	NOUN
gra-2157	14	13	of	of	ADP
gra-2157	14	14	advanced	advanced	ADJ
gra-2157	14	15	glycation	glycation	NOUN
gra-2157	14	16	end	end	NOUN
gra-2157	14	17	-	-	PUNCT
gra-2157	14	18	products	product	NOUN
gra-2157	14	19	(	(	PUNCT
gra-2157	14	20	ages	age	NOUN
gra-2157	14	21	)	)	PUNCT
gra-2157	14	22	,	,	PUNCT
gra-2157	14	23	protein	protein	NOUN
gra-2157	14	24	kinase	kinase	PROPN
gra-2157	14	25	c	c	PROPN
gra-2157	14	26	(	(	PUNCT
gra-2157	14	27	pkc	pkc	NOUN
gra-2157	14	28	)	)	PUNCT
gra-2157	14	29	activation	activation	NOUN
gra-2157	14	30	,	,	PUNCT
gra-2157	14	31	and	and	CCONJ
gra-2157	14	32	enhanced	enhance	VERB
gra-2157	14	33	production	production	NOUN
gra-2157	14	34	of	of	ADP
gra-2157	14	35	reactive	reactive	ADJ
gra-2157	14	36	oxygen	oxygen	NOUN
gra-2157	14	37	species	specie	NOUN
gra-2157	14	38	(	(	PUNCT
gra-2157	14	39	ros	ros	PROPN
gra-2157	14	40	)	)	PUNCT
gra-2157	14	41	have	have	AUX
gra-2157	14	42	been	be	AUX
gra-2157	14	43	proposed	propose	VERB
gra-2157	14	44	to	to	PART
gra-2157	14	45	contribute	contribute	VERB
gra-2157	14	46	to	to	ADP
gra-2157	14	47	the	the	DET
gra-2157	14	48	characteristic	characteristic	ADJ
gra-2157	14	49	histopathological	histopathological	ADJ
gra-2157	14	50	changes	change	NOUN
gra-2157	14	51	associated	associate	VERB
gra-2157	14	52	with	with	ADP
gra-2157	14	53	2diabetic	2diabetic	NUM
gra-2157	14	54	nephropathy	nephropathy	NOUN
gra-2157	14	55	.	.	PUNCT
gra-2157	15	1	diabetic	diabetic	ADJ
gra-2157	15	2	nephropathy	nephropathy	NOUN
gra-2157	15	3	is	be	AUX
gra-2157	15	4	characterized	characterize	VERB
gra-2157	15	5	by	by	ADP
gra-2157	15	6	glomerular	glomerular	ADJ
gra-2157	15	7	and	and	CCONJ
gra-2157	15	8	tubular	tubular	ADJ
gra-2157	15	9	basement	basement	NOUN
gra-2157	15	10	membrane	membrane	NOUN
gra-2157	15	11	thickening	thickening	NOUN
gra-2157	15	12	,	,	PUNCT
gra-2157	15	13	extracellular	extracellular	ADJ
gra-2157	15	14	matrix	matrix	NOUN
gra-2157	15	15	(	(	PUNCT
gra-2157	15	16	ecm	ecm	NOUN
gra-2157	15	17	)	)	PUNCT
gra-2157	15	18	expansion	expansion	NOUN
gra-2157	15	19	,	,	PUNCT
gra-2157	15	20	microvascular	microvascular	ADJ
gra-2157	15	21	damage	damage	NOUN
gra-2157	15	22	,	,	PUNCT
gra-2157	15	23	and	and	CCONJ
gra-2157	15	24	brotic	brotic	ADJ
gra-2157	15	25	changes	change	NOUN
gra-2157	15	26	in	in	ADP
gra-2157	15	27	the	the	DET
gra-2157	15	28	tubule	tubule	NOUN
gra-2157	15	29	-	-	PUNCT
gra-2157	15	30	interstitium	interstitium	NOUN
gra-2157	15	31	.	.	PUNCT
gra-2157	16	1	hypertension	hypertension	NOUN
gra-2157	16	2	further	far	ADV
gra-2157	16	3	increases	increase	VERB
gra-2157	16	4	the	the	DET
gra-2157	16	5	risk	risk	NOUN
gra-2157	16	6	for	for	ADP
gra-2157	16	7	onset	onset	NOUN
gra-2157	16	8	of	of	ADP
gra-2157	16	9	kidney	kidney	NOUN
gra-2157	16	10	disease	disease	NOUN
gra-2157	16	11	and	and	CCONJ
gra-2157	16	12	progression	progression	NOUN
gra-2157	16	13	and	and	CCONJ
gra-2157	16	14	cardiovascular	cardiovascular	ADJ
gra-2157	16	15	(	(	PUNCT
gra-2157	16	16	cv	cv	ADJ
gra-2157	16	17	)	)	PUNCT
gra-2157	16	18	morbidity	morbidity	NOUN
gra-2157	16	19	and	and	CCONJ
gra-2157	16	20	mortality	mortality	NOUN
gra-2157	16	21	.	.	PUNCT
gra-2157	17	1	multiple	multiple	ADJ
gra-2157	17	2	factors	factor	NOUN
gra-2157	17	3	contribute	contribute	VERB
gra-2157	17	4	to	to	ADP
gra-2157	17	5	increases	increase	NOUN
gra-2157	17	6	in	in	ADP
gra-2157	17	7	blood	blood	NOUN
gra-2157	17	8	pressure	pressure	NOUN
gra-2157	17	9	and	and	CCONJ
gra-2157	17	10	hypertension	hypertension	NOUN
gra-2157	17	11	in	in	ADP
gra-2157	17	12	patients	patient	NOUN
gra-2157	17	13	with	with	ADP
gra-2157	17	14	diabetes	diabetes	NOUN
gra-2157	17	15	and	and	CCONJ
gra-2157	17	16	nephropathy	nephropathy	NOUN
gra-2157	17	17	.	.	PUNCT
gra-2157	18	1	the	the	DET
gra-2157	18	2	major	major	ADJ
gra-2157	18	3	causes	cause	NOUN
gra-2157	18	4	of	of	ADP
gra-2157	18	5	hypertension	hypertension	NOUN
gra-2157	18	6	in	in	ADP
gra-2157	18	7	both	both	DET
gra-2157	18	8	diabetes	diabetes	NOUN
gra-2157	18	9	type	type	NOUN
gra-2157	18	10	i	i	PRON
gra-2157	18	11	as	as	ADV
gra-2157	18	12	well	well	ADV
gra-2157	18	13	as	as	ADP
gra-2157	18	14	type	type	NOUN
gra-2157	18	15	ii	ii	PROPN
gra-2157	18	16	include	include	VERB
gra-2157	18	17	volume	volume	NOUN
gra-2157	18	18	expansion	expansion	NOUN
gra-2157	18	19	owing	owe	VERB
gra-2157	18	20	to	to	ADP
gra-2157	18	21	increased	increase	VERB
gra-2157	18	22	renal	renal	ADJ
gra-2157	18	23	sodium	sodium	NOUN
gra-2157	18	24	reabsorption	reabsorption	NOUN
gra-2157	18	25	and	and	CCONJ
gra-2157	18	26	peripheral	peripheral	ADJ
gra-2157	18	27	vasoconstriction	vasoconstriction	NOUN
gra-2157	18	28	as	as	ADP
gra-2157	18	29	a	a	DET
gra-2157	18	30	result	result	NOUN
gra-2157	18	31	of	of	ADP
gra-2157	18	32	dysregulation	dysregulation	NOUN
gra-2157	18	33	of	of	ADP
gra-2157	18	34	factors	factor	NOUN
gra-2157	18	35	that	that	PRON
gra-2157	18	36	regulate	regulate	VERB
gra-2157	18	37	peripheral	peripheral	ADJ
gra-2157	18	38	vascular	vascular	ADJ
gra-2157	18	39	resistance	resistance	NOUN
gra-2157	18	40	.	.	PUNCT
gra-2157	19	1	excess	excess	ADJ
gra-2157	19	2	sodium	sodium	NOUN
gra-2157	19	3	retention	retention	NOUN
gra-2157	19	4	,	,	PUNCT
gra-2157	19	5	activation	activation	NOUN
gra-2157	19	6	of	of	ADP
gra-2157	19	7	the	the	DET
gra-2157	19	8	sympathetic	sympathetic	ADJ
gra-2157	19	9	nervous	nervous	ADJ
gra-2157	19	10	system	system	NOUN
gra-2157	19	11	(	(	PUNCT
gra-2157	19	12	sns	sns	PROPN
gra-2157	19	13	)	)	PUNCT
gra-2157	19	14	and	and	CCONJ
gra-2157	19	15	raas	raas	NOUN
gra-2157	19	16	,	,	PUNCT
gra-2157	19	17	endothelial	endothelial	ADJ
gra-2157	19	18	cell	cell	NOUN
gra-2157	19	19	dysfunction	dysfunction	NOUN
gra-2157	19	20	(	(	PUNCT
gra-2157	19	21	ecd	ecd	PROPN
gra-2157	19	22	)	)	PUNCT
gra-2157	19	23	,	,	PUNCT
gra-2157	19	24	and	and	CCONJ
gra-2157	19	25	increased	increase	VERB
gra-2157	19	26	oxidative	oxidative	ADJ
gra-2157	19	27	stress	stress	NOUN
gra-2157	19	28	leads	lead	VERB
gra-2157	19	29	to	to	ADP
gra-2157	19	30	hypertension	hypertension	NOUN
gra-2157	19	31	in	in	ADP
gra-2157	19	32	diabetic	diabetic	ADJ
gra-2157	19	33	4nephropathy	4nephropathy	NUM
gra-2157	19	34	.	.	PUNCT
gra-2157	20	1	angiotensin	angiotensin	NOUN
gra-2157	20	2	-	-	PUNCT
gra-2157	20	3	converting	convert	VERB
gra-2157	20	4	enzyme	enzyme	NOUN
gra-2157	20	5	(	(	PUNCT
gra-2157	20	6	ace	ace	NOUN
gra-2157	20	7	)	)	PUNCT
gra-2157	20	8	inhibitors	inhibitor	NOUN
gra-2157	20	9	and	and	CCONJ
gra-2157	20	10	angiotensin	angiotensin	NOUN
gra-2157	20	11	-	-	PUNCT
gra-2157	20	12	ii	ii	NOUN
gra-2157	20	13	type	type	NOUN
gra-2157	20	14	1	1	NUM
gra-2157	20	15	(	(	PUNCT
gra-2157	20	16	at1	at1	PROPN
gra-2157	20	17	)	)	PUNCT
gra-2157	20	18	receptor	receptor	NOUN
gra-2157	20	19	blockers	blocker	NOUN
gra-2157	20	20	(	(	PUNCT
gra-2157	20	21	arbs	arb	NOUN
gra-2157	20	22	)	)	PUNCT
gra-2157	20	23	are	be	AUX
gra-2157	20	24	often	often	ADV
gra-2157	20	25	employed	employ	VERB
gra-2157	20	26	to	to	PART
gra-2157	20	27	treat	treat	VERB
gra-2157	20	28	diabetic	diabetic	ADJ
gra-2157	20	29	nephropathy	nephropathy	NOUN
gra-2157	20	30	.	.	PUNCT
gra-2157	21	1	although	although	SCONJ
gra-2157	21	2	new	new	ADJ
gra-2157	21	3	strategies	strategy	NOUN
gra-2157	21	4	for	for	ADP
gra-2157	21	5	treating	treat	VERB
gra-2157	21	6	nephropathy	nephropathy	NOUN
gra-2157	21	7	are	be	AUX
gra-2157	21	8	req	req	ADV
gra-2157	21	9	uired	uired	ADJ
gra-2157	21	10	as	as	SCONJ
gra-2157	21	11	current	current	ADJ
gra-2157	21	12	approaches	approach	NOUN
gra-2157	21	13	are	be	AUX
gra-2157	21	14	insufcient	insufcient	ADJ
gra-2157	21	15	since	since	SCONJ
gra-2157	21	16	most	most	ADJ
gra-2157	21	17	of	of	ADP
gra-2157	21	18	the	the	DET
gra-2157	21	19	diabetic	diabetic	ADJ
gra-2157	21	20	patients	patient	NOUN
gra-2157	21	21	continue	continue	VERB
gra-2157	21	22	to	to	PART
gra-2157	21	23	show	show	VERB
gra-2157	21	24	progressive	progressive	ADJ
gra-2157	21	25	renal	renal	ADJ
gra-2157	21	26	damage	damage	NOUN
gra-2157	21	27	.	.	PUNCT
gra-2157	22	1	new	new	ADJ
gra-2157	22	2	studies	study	NOUN
gra-2157	22	3	indicate	indicate	VERB
gra-2157	22	4	the	the	DET
gra-2157	22	5	therapeutic	therapeutic	ADJ
gra-2157	22	6	potential	potential	NOUN
gra-2157	22	7	of	of	ADP
gra-2157	22	8	peroxisome	peroxisome	NOUN
gra-2157	22	9	proliferator	proliferator	NOUN
gra-2157	22	10	-	-	PUNCT
gra-2157	22	11	activated	activate	VERB
gra-2157	22	12	receptors	receptor	NOUN
gra-2157	22	13	(	(	PUNCT
gra-2157	22	14	ppar	ppar	NOUN
gra-2157	22	15	)	)	PUNCT
gra-2157	22	16	ligands	ligand	NOUN
gra-2157	22	17	in	in	ADP
gra-2157	22	18	the	the	DET
gra-2157	22	19	treat	treat	NOUN
gra-2157	22	20	5,6ment	5,6ment	NUM
gra-2157	22	21	of	of	ADP
gra-2157	22	22	patients	patient	NOUN
gra-2157	22	23	with	with	ADP
gra-2157	22	24	diabetic	diabetic	ADJ
gra-2157	22	25	nephropathy	nephropathy	NOUN
gra-2157	22	26	.	.	PUNCT
gra-2157	23	1	ppars	ppar	NOUN
gra-2157	23	2	are	be	AUX
gra-2157	23	3	ligand	ligand	NOUN
gra-2157	23	4	-	-	PUNCT
gra-2157	23	5	activated	activate	VERB
gra-2157	23	6	transcription	transcription	NOUN
gra-2157	23	7	factors	factor	NOUN
gra-2157	23	8	of	of	ADP
gra-2157	23	9	nuclear	nuclear	ADJ
gra-2157	23	10	hormone	hormone	NOUN
gra-2157	23	11	receptor	receptor	NOUN
gra-2157	23	12	superfamily	superfamily	NOUN
gra-2157	23	13	,	,	PUNCT
gra-2157	23	14	which	which	PRON
gra-2157	23	15	comprises	comprise	VERB
gra-2157	23	16	of	of	ADP
gra-2157	23	17	three	three	NUM
gra-2157	23	18	members	member	NOUN
gra-2157	23	19	such	such	ADJ
gra-2157	23	20	as	as	ADP
gra-2157	23	21	ppar	ppar	NOUN
gra-2157	23	22	α	α	NOUN
gra-2157	23	23	,	,	PUNCT
gra-2157	23	24	ppar	ppar	NOUN
gra-2157	23	25	ß	ß	NOUN
gra-2157	23	26	and	and	CCONJ
gra-2157	23	27	ppar	ppar	NOUN
gra-2157	23	28	γ	γ	PROPN
gra-2157	23	29	/	/	SYM
gra-2157	23	30	δ	δ	PROPN
gra-2157	23	31	.	.	PUNCT
gra-2157	24	1	ppar	ppar	NOUN
gra-2157	24	2	α	α	PRON
gra-2157	24	3	plays	play	VERB
gra-2157	24	4	an	an	DET
gra-2157	24	5	important	important	ADJ
gra-2157	24	6	role	role	NOUN
gra-2157	24	7	in	in	ADP
gra-2157	24	8	the	the	DET
gra-2157	24	9	oxidation	oxidation	NOUN
gra-2157	24	10	of	of	ADP
gra-2157	24	11	fatty	fatty	NOUN
gra-2157	24	12	acids	acid	NOUN
gra-2157	24	13	.	.	PUNCT
gra-2157	25	1	studies	study	NOUN
gra-2157	25	2	suggest	suggest	VERB
gra-2157	25	3	that	that	SCONJ
gra-2157	25	4	hyperlipidemia	hyperlipidemia	NOUN
gra-2157	25	5	is	be	AUX
gra-2157	25	6	an	an	DET
gra-2157	25	7	independent	independent	ADJ
gra-2157	25	8	risk	risk	NOUN
gra-2157	25	9	factor	factor	NOUN
gra-2157	25	10	involved	involve	VERB
gra-2157	25	11	in	in	ADP
gra-2157	25	12	the	the	DET
gra-2157	25	13	7–9development	7–9development	NUM
gra-2157	25	14	of	of	ADP
gra-2157	25	15	diabetic	diabetic	ADJ
gra-2157	25	16	nephropathy	nephropathy	NOUN
gra-2157	25	17	.	.	PUNCT
gra-2157	26	1	the	the	DET
gra-2157	26	2	elevated	elevated	ADJ
gra-2157	26	3	levels	level	NOUN
gra-2157	26	4	of	of	ADP
gra-2157	26	5	lipids	lipid	NOUN
gra-2157	26	6	are	be	AUX
gra-2157	26	7	associated	associate	VERB
gra-2157	26	8	with	with	ADP
gra-2157	26	9	the	the	DET
gra-2157	26	10	progression	progression	NOUN
gra-2157	26	11	of	of	ADP
gra-2157	26	12	renal	renal	ADJ
gra-2157	26	13	10dysfunction	10dysfunction	NOUN
gra-2157	26	14	.	.	PUNCT
gra-2157	27	1	the	the	DET
gra-2157	27	2	increase	increase	NOUN
gra-2157	27	3	in	in	ADP
gra-2157	27	4	circulating	circulate	VERB
gra-2157	27	5	lipids	lipid	NOUN
gra-2157	27	6	induces	induce	NOUN
gra-2157	27	7	glomerulosclerosis	glomerulosclerosis	NOUN
gra-2157	27	8	and	and	CCONJ
gra-2157	27	9	tubule	tubule	ADJ
gra-2157	27	10	-	-	PUNCT
gra-2157	27	11	interstitial	interstitial	ADJ
gra-2157	27	12	injury	injury	NOUN
gra-2157	27	13	by	by	ADP
gra-2157	27	14	acceler	acceler	NOUN
gra-2157	27	15	ating	ate	VERB
gra-2157	27	16	the	the	DET
gra-2157	27	17	generation	generation	NOUN
gra-2157	27	18	of	of	ADP
gra-2157	27	19	reactive	reactive	ADJ
gra-2157	27	20	oxygen	oxygen	NOUN
gra-2157	27	21	species	specie	NOUN
gra-2157	27	22	(	(	PUNCT
gra-2157	27	23	ros	ros	PROPN
gra-2157	27	24	)	)	PUNCT
gra-2157	27	25	and	and	CCONJ
gra-2157	27	26	stimulating	stimulate	VERB
gra-2157	27	27	the	the	DET
gra-2157	27	28	overexpression	overexpression	NOUN
gra-2157	27	29	of	of	ADP
gra-2157	27	30	transforming	transform	VERB
gra-2157	27	31	growth	growth	NOUN
gra-2157	27	32	factor	factor	NOUN
gra-2157	27	33	ß	ß	X
gra-2157	27	34	(	(	PUNCT
gra-2157	27	35	tgf	tgf	PROPN
gra-2157	27	36	-	-	PUNCT
gra-2157	27	37	ß	ß	NOUN
gra-2157	27	38	)	)	PUNCT
gra-2157	27	39	in	in	ADP
gra-2157	27	40	the	the	DET
gra-2157	27	41	glomeruli	glomeruli	NOUN
gra-2157	27	42	and	and	CCONJ
gra-2157	27	43	tubule	tubule	NOUN
gra-2157	27	44	-	-	PUNCT
gra-2157	27	45	interstitium	interstitium	NOUN
gra-2157	27	46	.	.	PUNCT
gra-2157	28	1	it	it	PRON
gra-2157	28	2	was	be	AUX
gra-2157	28	3	suggested	suggest	VERB
gra-2157	28	4	that	that	SCONJ
gra-2157	28	5	circulating	circulate	VERB
gra-2157	28	6	lipids	lipid	NOUN
gra-2157	28	7	are	be	AUX
gra-2157	28	8	entrapped	entrap	VERB
gra-2157	28	9	by	by	ADP
gra-2157	28	10	extracellular	extracellular	ADJ
gra-2157	28	11	matrix	matrix	NOUN
gra-2157	28	12	molecules	molecule	NOUN
gra-2157	28	13	where	where	SCONJ
gra-2157	28	14	they	they	PRON
gra-2157	28	15	undergo	undergo	VERB
gra-2157	28	16	the	the	DET
gra-2157	28	17	process	process	NOUN
gra-2157	28	18	of	of	ADP
gra-2157	28	19	lipid	lipid	NOUN
gra-2157	28	20	peroxidation	peroxidation	NOUN
gra-2157	28	21	and	and	CCONJ
gra-2157	28	22	generate	generate	VERB
gra-2157	28	23	ros	ros	PROPN
gra-2157	28	24	to	to	PART
gra-2157	28	25	induce	induce	VERB
gra-2157	28	26	10renal	10renal	ADJ
gra-2157	28	27	dysfunction	dysfunction	NOUN
gra-2157	28	28	.	.	PUNCT
gra-2157	29	1	further	further	ADJ
gra-2157	29	2	evidence	evidence	NOUN
gra-2157	29	3	revealed	reveal	VERB
gra-2157	29	4	that	that	SCONJ
gra-2157	29	5	diabetes	diabetes	NOUN
gra-2157	29	6	may	may	AUX
gra-2157	29	7	mediate	mediate	VERB
gra-2157	29	8	renal	renal	ADJ
gra-2157	29	9	injury	injury	NOUN
gra-2157	29	10	by	by	ADP
gra-2157	29	11	increasing	increase	VERB
gra-2157	29	12	the	the	DET
gra-2157	29	13	expression	expression	NOUN
gra-2157	29	14	of	of	ADP
gra-2157	29	15	sterol	sterol	NOUN
gra-2157	29	16	regulatory	regulatory	ADJ
gra-2157	29	17	element	element	NOUN
gra-2157	29	18	-	-	PUNCT
gra-2157	29	19	binding	bind	VERB
gra-2157	29	20	protein-1	protein-1	NUM
gra-2157	29	21	(	(	PUNCT
gra-2157	29	22	srebp-1	srebp-1	NOUN
gra-2157	29	23	)	)	PUNCT
gra-2157	29	24	,	,	PUNCT
gra-2157	29	25	which	which	PRON
gra-2157	29	26	are	be	AUX
gra-2157	29	27	responsible	responsible	ADJ
gra-2157	29	28	for	for	ADP
gra-2157	29	29	increasing	increase	VERB
gra-2157	29	30	the	the	DET
gra-2157	29	31	synthesis	synthesis	NOUN
gra-2157	29	32	of	of	ADP
gra-2157	29	33	triglycerides	triglyceride	NOUN
gra-2157	29	34	and	and	CCONJ
gra-2157	29	35	cholesterol	cholesterol	NOUN
gra-2157	29	36	in	in	ADP
gra-2157	29	37	the	the	DET
gra-2157	29	38	kidney	kidney	NOUN
gra-2157	29	39	,	,	PUNCT
gra-2157	29	40	that	that	PRON
gra-2157	29	41	is	be	AUX
gra-2157	29	42	associated	associate	VERB
gra-2157	29	43	with	with	ADP
gra-2157	29	44	the	the	DET
gra-2157	29	45	upregulation	upregulation	NOUN
gra-2157	29	46	of	of	ADP
gra-2157	29	47	tgf	tgf	PROPN
gra-2157	29	48	-	-	PUNCT
gra-2157	29	49	ß	ß	NOUN
gra-2157	29	50	,	,	PUNCT
gra-2157	29	51	vascular	vascular	ADJ
gra-2157	29	52	endothelial	endothelial	ADJ
gra-2157	29	53	growth	growth	NOUN
gra-2157	29	54	factor	factor	NOUN
gra-2157	29	55	(	(	PUNCT
gra-2157	29	56	vegf	vegf	PROPN
gra-2157	29	57	)	)	PUNCT
gra-2157	29	58	and	and	CCONJ
gra-2157	29	59	extracellular	extracellular	ADJ
gra-2157	29	60	matrix	matrix	NOUN
gra-2157	29	61	proteins	protein	NOUN
gra-2157	29	62	,	,	PUNCT
gra-2157	29	63	resulting	result	VERB
gra-2157	29	64	in	in	ADP
gra-2157	29	65	glomerulosclerosis	glomerulosclerosis	NOUN
gra-2157	29	66	and	and	CCONJ
gra-2157	29	67	tubule	tubule	ADJ
gra-2157	29	68	-	-	PUNCT
gra-2157	29	69	interstitial	interstitial	ADJ
gra-2157	29	70	brosis	brosis	PROPN
gra-2157	29	71	to	to	PART
gra-2157	29	72	provoke	provoke	VERB
gra-2157	29	73	11,12diabetic	11,12diabetic	NUM
gra-2157	29	74	nephropathy	nephropathy	NOUN
gra-2157	29	75	.	.	PUNCT
gra-2157	30	1	hence	hence	ADV
gra-2157	30	2	,	,	PUNCT
gra-2157	30	3	reducing	reduce	VERB
gra-2157	30	4	the	the	DET
gra-2157	30	5	circulating	circulate	VERB
gra-2157	30	6	lipids	lipid	NOUN
gra-2157	30	7	in	in	ADP
gra-2157	30	8	diabetic	diabetic	ADJ
gra-2157	30	9	patients	patient	NOUN
gra-2157	30	10	may	may	AUX
gra-2157	30	11	provide	provide	VERB
gra-2157	30	12	a	a	DET
gra-2157	30	13	new	new	ADJ
gra-2157	30	14	therapeutic	therapeutic	ADJ
gra-2157	30	15	option	option	NOUN
gra-2157	30	16	in	in	ADP
gra-2157	30	17	managing	manage	VERB
gra-2157	30	18	diabetic	diabetic	ADJ
gra-2157	30	19	nephropathy	nephropathy	NOUN
gra-2157	30	20	.	.	PUNCT
gra-2157	31	1	the	the	DET
gra-2157	31	2	agent	agent	NOUN
gra-2157	31	3	like	like	ADP
gra-2157	31	4	ppar	ppar	NOUN
gra-2157	31	5	�	�	PROPN
gra-2157	31	6	agonists	agonist	NOUN
gra-2157	31	7	has	have	AUX
gra-2157	31	8	been	be	AUX
gra-2157	31	9	suggested	suggest	VERB
gra-2157	31	10	as	as	ADP
gra-2157	31	11	a	a	DET
gra-2157	31	12	novel	novel	NOUN
gra-2157	31	13	therapeutic	therapeutic	ADJ
gra-2157	31	14	13intervention	13intervention	NOUN
gra-2157	31	15	to	to	PART
gra-2157	31	16	manage	manage	VERB
gra-2157	31	17	diabetic	diabetic	ADJ
gra-2157	31	18	nephropathy	nephropathy	NOUN
gra-2157	31	19	.	.	PUNCT
gra-2157	32	1	moreover	moreover	ADV
gra-2157	32	2	,	,	PUNCT
gra-2157	32	3	adiponectin	adiponectin	NOUN
gra-2157	32	4	,	,	PUNCT
gra-2157	32	5	an	an	DET
gra-2157	32	6	adipose	adipose	ADJ
gra-2157	32	7	tissue	tissue	NOUN
gra-2157	32	8	-	-	PUNCT
gra-2157	32	9	derived	derive	VERB
gra-2157	32	10	secreted	secrete	VERB
gra-2157	32	11	cytokine	cytokine	NOUN
gra-2157	32	12	,	,	PUNCT
gra-2157	32	13	has	have	AUX
gra-2157	32	14	been	be	AUX
gra-2157	32	15	found	find	VERB
gra-2157	32	16	to	to	PART
gra-2157	32	17	have	have	VERB
gra-2157	32	18	insulin	insulin	NOUN
gra-2157	32	19	-	-	PUNCT
gra-2157	32	20	sensitizing	sensitize	VERB
gra-2157	32	21	,	,	PUNCT
gra-2157	32	22	antiinammatory	antiinammatory	NOUN
gra-2157	32	23	,	,	PUNCT
gra-2157	32	24	and	and	CCONJ
gra-2157	32	25	vasculoprotective	vasculoprotective	ADJ
gra-2157	32	26	actions	action	NOUN
gra-2157	32	27	through	through	ADP
gra-2157	32	28	binding	bind	VERB
gra-2157	32	29	to	to	ADP
gra-2157	32	30	its	its	PRON
gra-2157	32	31	receptors	receptor	NOUN
gra-2157	32	32	,	,	PUNCT
gra-2157	32	33	adipor1	adipor1	NOUN
gra-2157	32	34	and	and	CCONJ
gra-2157	32	35	adipor2	adipor2	PROPN
gra-2157	32	36	.	.	PUNCT
gra-2157	33	1	these	these	DET
gra-2157	33	2	two	two	NUM
gra-2157	33	3	adiponectin	adiponectin	NOUN
gra-2157	33	4	receptors	receptor	NOUN
gra-2157	33	5	have	have	AUX
gra-2157	33	6	been	be	AUX
gra-2157	33	7	previously	previously	ADV
gra-2157	33	8	shown	show	VERB
gra-2157	33	9	to	to	PART
gra-2157	33	10	mediate	mediate	VERB
gra-2157	33	11	the	the	DET
gra-2157	33	12	increase	increase	NOUN
gra-2157	33	13	in	in	ADP
gra-2157	33	14	ampk	ampk	NOUN
gra-2157	33	15	activities	activity	NOUN
gra-2157	33	16	,	,	PUNCT
gra-2157	33	17	as	as	ADV
gra-2157	33	18	well	well	ADV
gra-2157	33	19	as	as	ADP
gra-2157	33	20	fatty	fatty	NOUN
gra-2157	33	21	acid	acid	NOUN
gra-2157	33	22	oxidation	oxidation	NOUN
gra-2157	33	23	and	and	CCONJ
gra-2157	33	24	glucose	glucose	NOUN
gra-2157	33	25	uptake	uptake	NOUN
gra-2157	33	26	by	by	ADP
gra-2157	33	27	adiponectin	adiponectin	NOUN
gra-2157	33	28	.	.	PUNCT
gra-2157	34	1	there	there	PRON
gra-2157	34	2	is	be	VERB
gra-2157	34	3	a	a	DET
gra-2157	34	4	growing	grow	VERB
gra-2157	34	5	body	body	NOUN
gra-2157	34	6	of	of	ADP
gra-2157	34	7	evidence	evidence	NOUN
gra-2157	34	8	demonstrating	demonstrate	VERB
gra-2157	34	9	the	the	DET
gra-2157	34	10	renoprotective	renoprotective	ADJ
gra-2157	34	11	functions	function	NOUN
gra-2157	34	12	of	of	ADP
gra-2157	34	13	adiponectin	adiponectin	NOUN
gra-2157	34	14	and	and	CCONJ
gra-2157	34	15	its	its	PRON
gra-2157	34	16	receptors	receptor	NOUN
gra-2157	34	17	,	,	PUNCT
gra-2157	34	18	which	which	PRON
gra-2157	34	19	protects	protect	VERB
gra-2157	34	20	against	against	ADP
gra-2157	34	21	the	the	DET
gra-2157	34	22	development	development	NOUN
gra-2157	34	23	of	of	ADP
gra-2157	34	24	3albuminuria	3albuminuria	NUM
gra-2157	34	25	.	.	PUNCT
gra-2157	35	1	thiazolidinediones	thiazolidinedione	NOUN
gra-2157	35	2	,	,	PUNCT
gra-2157	35	3	ligands	ligand	NOUN
gra-2157	35	4	for	for	ADP
gra-2157	35	5	ppar	ppar	NOUN
gra-2157	35	6	�	�	NOUN
gra-2157	35	7	,	,	PUNCT
gra-2157	35	8	have	have	AUX
gra-2157	35	9	been	be	AUX
gra-2157	35	10	employed	employ	VERB
gra-2157	35	11	for	for	ADP
gra-2157	35	12	the	the	DET
gra-2157	35	13	treatment	treatment	NOUN
gra-2157	35	14	of	of	ADP
gra-2157	35	15	type	type	NOUN
gra-2157	35	16	2	2	NUM
gra-2157	35	17	diabetes	diabetes	NOUN
gra-2157	35	18	mellitus	mellitus	NOUN
gra-2157	35	19	,	,	PUNCT
gra-2157	35	20	however	however	ADV
gra-2157	35	21	,	,	PUNCT
gra-2157	35	22	they	they	PRON
gra-2157	35	23	have	have	AUX
gra-2157	35	24	been	be	AUX
gra-2157	35	25	found	find	VERB
gra-2157	35	26	to	to	PART
gra-2157	35	27	increase	increase	VERB
gra-2157	35	28	the	the	DET
gra-2157	35	29	risk	risk	NOUN
gra-2157	35	30	of	of	ADP
gra-2157	35	31	myocardial	myocardial	ADJ
gra-2157	35	32	infarction	infarction	NOUN
gra-2157	35	33	and	and	CCONJ
gra-2157	35	34	heart	heart	NOUN
gra-2157	35	35	failure	failure	NOUN
gra-2157	35	36	.	.	PUNCT
gra-2157	36	1	however	however	ADV
gra-2157	36	2	,	,	PUNCT
gra-2157	36	3	telmisartan	telmisartan	PROPN
gra-2157	36	4	has	have	AUX
gra-2157	36	5	been	be	AUX
gra-2157	36	6	suggested	suggest	VERB
gra-2157	36	7	to	to	PART
gra-2157	36	8	be	be	AUX
gra-2157	36	9	devoid	devoid	ADJ
gra-2157	36	10	of	of	ADP
gra-2157	36	11	these	these	DET
gra-2157	36	12	undesirable	undesirable	ADJ
gra-2157	36	13	effects	effect	NOUN
gra-2157	36	14	.	.	PUNCT
gra-2157	37	1	thus	thus	ADV
gra-2157	37	2	,	,	PUNCT
gra-2157	37	3	telmisartan	telmisartan	PROPN
gra-2157	37	4	could	could	AUX
gra-2157	37	5	be	be	AUX
gra-2157	37	6	a	a	DET
gra-2157	37	7	novel	novel	ADJ
gra-2157	37	8	therapeutic	therapeutic	ADJ
gra-2157	37	9	choice	choice	NOUN
gra-2157	37	10	to	to	PART
gra-2157	37	11	treat	treat	VERB
gra-2157	37	12	co	co	ADJ
gra-2157	37	13	-	-	ADJ
gra-2157	37	14	existing	existing	ADJ
gra-2157	37	15	diabetes	diabetes	NOUN
gra-2157	37	16	mellitus	mellitus	NOUN
gra-2157	37	17	and	and	CCONJ
gra-2157	37	18	hypertension	hypertension	NOUN
gra-2157	37	19	-	-	PUNCT
gra-2157	37	20	associated	associate	VERB
gra-2157	37	21	role	role	NOUN
gra-2157	37	22	of	of	ADP
gra-2157	37	23	telmisartan	telmisartan	NOUN
gra-2157	37	24	in	in	ADP
gra-2157	37	25	diabetic	diabetic	ADJ
gra-2157	37	26	nephropathy	nephropathy	NOUN
gra-2157	37	27	a	a	DET
gra-2157	37	28	novel	novel	ADJ
gra-2157	37	29	treatment	treatment	NOUN
gra-2157	37	30	avenue	avenue	NOUN
gra-2157	37	31	original	original	ADJ
gra-2157	37	32	research	research	NOUN
gra-2157	37	33	paper	paper	NOUN
gra-2157	37	34	dr	dr	PROPN
gra-2157	37	35	manash	manash	PROPN
gra-2157	37	36	das	das	PROPN
gra-2157	37	37	settlement	settlement	PROPN
gra-2157	37	38	road	road	NOUN
gra-2157	37	39	,	,	PUNCT
gra-2157	37	40	ward	ward	VERB
gra-2157	37	41	no-1.karimganj-788712,assam	no-1.karimganj-788712,assam	PROPN
gra-2157	37	42	medicine	medicine	NOUN
gra-2157	37	43	keywords	keyword	NOUN
gra-2157	37	44	:	:	PUNCT
gra-2157	37	45	volume-9	volume-9	NUM
gra-2157	37	46	,	,	PUNCT
gra-2157	37	47	issue-3	issue-3	NUM
gra-2157	37	48	,	,	PUNCT
gra-2157	37	49	march-2020	march-2020	ADJ
gra-2157	37	50	•	•	NOUN
gra-2157	37	51	print	print	NOUN
gra-2157	37	52	issn	issn	PROPN
gra-2157	37	53	no	no	NOUN
gra-2157	37	54	.	.	PROPN
gra-2157	37	55	2277	2277	NUM
gra-2157	37	56	8160	8160	NUM
gra-2157	37	57	•	•	NOUN
gra-2157	37	58	doi	doi	NOUN
gra-2157	37	59	:	:	PUNCT
gra-2157	37	60	10.36106	10.36106	NUM
gra-2157	37	61	/	/	SYM
gra-2157	37	62	gjra	gjra	PROPN
gra-2157	37	63	dr	dr	PROPN
gra-2157	37	64	md	md	PROPN
gra-2157	37	65	anfas	anfas	PROPN
gra-2157	37	66	nusrat	nusrat	PROPN
gra-2157	37	67	pasha	pasha	PROPN
gra-2157	37	68	*	*	PROPN
gra-2157	37	69	shine	shine	VERB
gra-2157	37	70	speciality	speciality	NOUN
gra-2157	37	71	clinics	clinic	NOUN
gra-2157	37	72	,	,	PUNCT
gra-2157	37	73	laxmi	laxmi	NOUN
gra-2157	37	74	nagar	nagar	NOUN
gra-2157	37	75	colony	colony	NOUN
gra-2157	37	76	,	,	PUNCT
gra-2157	37	77	shaikpet	shaikpet	NOUN
gra-2157	37	78	,	,	PUNCT
gra-2157	37	79	hyderabad	hyderabad	NOUN
gra-2157	37	80	*	*	PUNCT
gra-2157	37	81	corresponding	correspond	VERB
gra-2157	37	82	author	author	NOUN
gra-2157	37	83	dr	dr	PROPN
gra-2157	37	84	mukesh	mukesh	PROPN
gra-2157	37	85	gupta	gupta	PROPN
gra-2157	37	86	daksh	daksh	PROPN
gra-2157	37	87	hospital	hospital	NOUN
gra-2157	37	88	,	,	PUNCT
gra-2157	37	89	gandhi	gandhi	PROPN
gra-2157	37	90	nagar	nagar	PROPN
gra-2157	37	91	,	,	PUNCT
gra-2157	37	92	alwar	alwar	PROPN
gra-2157	37	93	,	,	PUNCT
gra-2157	37	94	pin301001	pin301001	PROPN
gra-2157	37	95	dr	dr	PROPN
gra-2157	37	96	mriganka	mriganka	PROPN
gra-2157	37	97	baruah	baruah	PROPN
gra-2157	37	98	vg	vg	ADP
gra-2157	37	99	hospital	hospital	NOUN
gra-2157	37	100	,	,	PUNCT
gra-2157	37	101	convoy	convoy	NOUN
gra-2157	37	102	road	road	NOUN
gra-2157	37	103	,	,	PUNCT
gra-2157	37	104	dibrugarh	dibrugarh	NOUN
gra-2157	37	105	,	,	PUNCT
gra-2157	37	106	assam,786001	assam,786001	VERB
gra-2157	37	107	dr	dr	PROPN
gra-2157	37	108	navneet	navneet	PROPN
gra-2157	37	109	maini	maini	PROPN
gra-2157	37	110	5	5	NUM
gra-2157	37	111	rb	rb	PROPN
gra-2157	37	112	duni	duni	PROPN
gra-2157	37	113	chand	chand	PROPN
gra-2157	37	114	road	road	PROPN
gra-2157	37	115	,	,	PUNCT
gra-2157	37	116	jamun	jamun	PROPN
gra-2157	37	117	wali	wali	PROPN
gra-2157	37	118	road	road	PROPN
gra-2157	37	119	amritsar	amritsar	PROPN
gra-2157	37	120	143001	143001	NUM
gra-2157	37	121	punjab	punjab	NOUN
gra-2157	37	122	.	.	PUNCT
gra-2157	38	1	38	38	NUM
gra-2157	38	2	x	x	SYM
gra-2157	38	3	gjra	gjra	ADJ
gra-2157	38	4	global	global	ADJ
gra-2157	38	5	journal	journal	PROPN
gra-2157	38	6	for	for	ADP
gra-2157	38	7	research	research	NOUN
gra-2157	38	8	analysis	analysis	NOUN
gra-2157	38	9	1progression	1progression	NUM
gra-2157	38	10	of	of	ADP
gra-2157	38	11	diabetic	diabetic	ADJ
gra-2157	38	12	nephropathy	nephropathy	NOUN
gra-2157	38	13	.	.	PUNCT
gra-2157	39	1	telmisartan	telmisartan	PROPN
gra-2157	39	2	is	be	AUX
gra-2157	39	3	a	a	DET
gra-2157	39	4	long	long	ADV
gra-2157	39	5	-	-	PUNCT
gra-2157	39	6	lasting	last	VERB
gra-2157	39	7	,	,	PUNCT
gra-2157	39	8	non	non	ADJ
gra-2157	39	9	-	-	ADJ
gra-2157	39	10	competitive/	competitive/	ADJ
gra-2157	39	11	insurmo	insurmo	NOUN
gra-2157	39	12	untable	untable	ADJ
gra-2157	39	13	,	,	PUNCT
gra-2157	39	14	non	non	ADJ
gra-2157	39	15	-	-	ADJ
gra-2157	39	16	peptide	peptide	ADJ
gra-2157	39	17	arb	arb	NOUN
gra-2157	39	18	with	with	ADP
gra-2157	39	19	the	the	DET
gra-2157	39	20	strongest	strong	ADJ
gra-2157	39	21	receptor	receptor	NOUN
gra-2157	39	22	binding	bind	VERB
gra-2157	39	23	afnity	afnity	NOUN
gra-2157	39	24	having	having	AUX
gra-2157	39	25	potent	potent	ADJ
gra-2157	39	26	anti	anti	ADJ
gra-2157	39	27	-	-	ADJ
gra-2157	39	28	hypertensive	hypertensive	ADJ
gra-2157	39	29	action	action	NOUN
gra-2157	39	30	.	.	PUNCT
gra-2157	40	1	telmisartan	telmisartan	PROPN
gra-2157	40	2	chemically	chemically	ADV
gra-2157	40	3	is	be	AUX
gra-2157	40	4	2-(4-{[4	2-(4-{[4	NOUN
gra-2157	40	5	-	-	PUNCT
gra-2157	40	6	methyl-6-(1	methyl-6-(1	NOUN
gra-2157	40	7	-	-	PUNCT
gra-2157	40	8	methyl-1h-1,3	methyl-1h-1,3	PROPN
gra-2157	40	9	-	-	PUNCT
gra-2157	40	10	benzodiazol2	benzodiazol2	NOUN
gra-2157	40	11	-	-	PUNCT
gra-2157	40	12	yl)-2propyl-1h-1	yl)-2propyl-1h-1	PROPN
gra-2157	40	13	,	,	PUNCT
gra-2157	40	14	3	3	NUM
gra-2157	40	15	-	-	SYM
gra-2157	40	16	benzodiazol-1	benzodiazol-1	NUM
gra-2157	40	17	yl	yl	NOUN
gra-2157	40	18	]	]	X
gra-2157	40	19	methyl	methyl	NOUN
gra-2157	40	20	}	}	PUNCT
gra-2157	40	21	phenyl	phenyl	NOUN
gra-2157	40	22	)	)	PUNCT
gra-2157	40	23	benzoic	benzoic	ADJ
gra-2157	40	24	acid	acid	NOUN
gra-2157	40	25	.	.	PUNCT
gra-2157	41	1	it	it	PRON
gra-2157	41	2	is	be	AUX
gra-2157	41	3	orally	orally	ADV
gra-2157	41	4	active	active	ADJ
gra-2157	41	5	and	and	CCONJ
gra-2157	41	6	possesses	possess	VERB
gra-2157	41	7	good	good	ADJ
gra-2157	41	8	oral	oral	ADJ
gra-2157	41	9	absorption	absorption	NOUN
gra-2157	41	10	and	and	CCONJ
gra-2157	41	11	tolerability	tolerability	NOUN
gra-2157	41	12	.	.	PUNCT
gra-2157	42	1	the	the	DET
gra-2157	42	2	oral	oral	ADJ
gra-2157	42	3	clearance	clearance	NOUN
gra-2157	42	4	was	be	AUX
gra-2157	42	5	associated	associate	VERB
gra-2157	42	6	with	with	ADP
gra-2157	42	7	age	age	NOUN
gra-2157	42	8	and	and	CCONJ
gra-2157	42	9	dose	dose	PROPN
gra-2157	42	10	.	.	PUNCT
gra-2157	43	1	the	the	DET
gra-2157	43	2	oral	oral	ADJ
gra-2157	43	3	clearance	clearance	NOUN
gra-2157	43	4	was	be	AUX
gra-2157	43	5	noted	note	VERB
gra-2157	43	6	to	to	PART
gra-2157	43	7	be	be	AUX
gra-2157	43	8	decreased	decrease	VERB
gra-2157	43	9	with	with	ADP
gra-2157	43	10	advanced	advanced	ADJ
gra-2157	43	11	age	age	NOUN
gra-2157	43	12	.	.	PUNCT
gra-2157	44	1	the	the	DET
gra-2157	44	2	volume	volume	NOUN
gra-2157	44	3	of	of	ADP
gra-2157	44	4	distribution	distribution	NOUN
gra-2157	44	5	for	for	ADP
gra-2157	44	6	the	the	DET
gra-2157	44	7	central	central	ADJ
gra-2157	44	8	compartment	compartment	NOUN
gra-2157	44	9	was	be	AUX
gra-2157	44	10	noted	note	VERB
gra-2157	44	11	to	to	PART
gra-2157	44	12	be	be	AUX
gra-2157	44	13	related	relate	VERB
gra-2157	44	14	to	to	ADP
gra-2157	44	15	age	age	NOUN
gra-2157	44	16	and	and	CCONJ
gra-2157	44	17	dose	dose	NOUN
gra-2157	44	18	,	,	PUNCT
gra-2157	44	19	and	and	CCONJ
gra-2157	44	20	the	the	DET
gra-2157	44	21	volume	volume	NOUN
gra-2157	44	22	of	of	ADP
gra-2157	44	23	distribution	distribution	NOUN
gra-2157	44	24	for	for	ADP
gra-2157	44	25	the	the	DET
gra-2157	44	26	peripheral	peripheral	ADJ
gra-2157	44	27	compartment	compartment	NOUN
gra-2157	44	28	was	be	AUX
gra-2157	44	29	noted	note	VERB
gra-2157	44	30	to	to	PART
gra-2157	44	31	be	be	AUX
gra-2157	44	32	related	relate	VERB
gra-2157	44	33	to	to	ADP
gra-2157	44	34	body	body	NOUN
gra-2157	44	35	weight	weight	NOUN
gra-2157	44	36	and	and	CCONJ
gra-2157	44	37	gender	gender	NOUN
gra-2157	44	38	.	.	PUNCT
gra-2157	45	1	the	the	DET
gra-2157	45	2	absolute	absolute	ADJ
gra-2157	45	3	bioavailability	bioavailability	NOUN
gra-2157	45	4	of	of	ADP
gra-2157	45	5	telmisartan	telmisartan	PROPN
gra-2157	45	6	is	be	AUX
gra-2157	45	7	dose	dose	NOUN
gra-2157	45	8	-	-	PUNCT
gra-2157	45	9	dependent	dependent	ADJ
gra-2157	45	10	,	,	PUNCT
gra-2157	45	11	and	and	CCONJ
gra-2157	45	12	food	food	NOUN
gra-2157	45	13	may	may	AUX
gra-2157	45	14	slightly	slightly	ADV
gra-2157	45	15	reduce	reduce	VERB
gra-2157	45	16	its	its	PRON
gra-2157	45	17	bioavailability	bioavailability	NOUN
gra-2157	45	18	.	.	PUNCT
gra-2157	46	1	it	it	PRON
gra-2157	46	2	is	be	AUX
gra-2157	46	3	a	a	DET
gra-2157	46	4	lipophilic	lipophilic	ADJ
gra-2157	46	5	compound	compound	NOUN
gra-2157	46	6	widely	widely	ADV
gra-2157	46	7	distri	distri	VERB
gra-2157	46	8	buted	bute	VERB
gra-2157	46	9	to	to	ADP
gra-2157	46	10	tissue	tissue	NOUN
gra-2157	46	11	and	and	CCONJ
gra-2157	46	12	is	be	AUX
gra-2157	46	13	highly	highly	ADV
gra-2157	46	14	bound	bind	VERB
gra-2157	46	15	to	to	AUX
gra-2157	46	16	plasma	plasma	VERB
gra-2157	46	17	proteins	protein	NOUN
gra-2157	46	18	up	up	ADP
gra-2157	46	19	to	to	PART
gra-2157	46	20	99.5	99.5	NUM
gra-2157	46	21	%	%	NOUN
gra-2157	46	22	.	.	PUNCT
gra-2157	47	1	telmisartan	telmisartan	PROPN
gra-2157	47	2	1	1	NUM
gra-2157	47	3	-	-	PUNCT
gra-2157	47	4	o	o	NOUN
gra-2157	47	5	-	-	NOUN
gra-2157	47	6	acylglucuronide	acylglucuronide	NOUN
gra-2157	47	7	is	be	AUX
gra-2157	47	8	the	the	DET
gra-2157	47	9	principal	principal	ADJ
gra-2157	47	10	metabolite	metabolite	NOUN
gra-2157	47	11	of	of	ADP
gra-2157	47	12	telmisartan	telmisartan	NOUN
gra-2157	47	13	in	in	ADP
gra-2157	47	14	humans	human	NOUN
gra-2157	47	15	.	.	PUNCT
gra-2157	48	1	biliary	biliary	ADJ
gra-2157	48	2	fecal	fecal	ADJ
gra-2157	48	3	excretion	excretion	NOUN
gra-2157	48	4	is	be	AUX
gra-2157	48	5	a	a	DET
gra-2157	48	6	primary	primary	ADJ
gra-2157	48	7	elimination	elimination	NOUN
gra-2157	48	8	route	route	NOUN
gra-2157	48	9	of	of	ADP
gra-2157	48	10	telmisartan	telmisartan	PROPN
gra-2157	48	11	and	and	CCONJ
gra-2157	48	12	its	its	PRON
gra-2157	48	13	metabolite	metabolite	NOUN
gra-2157	48	14	.	.	PUNCT
gra-2157	49	1	being	be	AUX
gra-2157	49	2	an	an	DET
gra-2157	49	3	arb	arb	NOUN
gra-2157	49	4	,	,	PUNCT
gra-2157	49	5	telmisartan	telmisartan	NOUN
gra-2157	49	6	reduces	reduce	VERB
gra-2157	49	7	high	high	ADJ
gra-2157	49	8	blood	blood	NOUN
gra-2157	49	9	pressure	pressure	NOUN
gra-2157	49	10	by	by	ADP
gra-2157	49	11	antagonizing	antagonize	VERB
gra-2157	49	12	the	the	DET
gra-2157	49	13	aforementioned	aforementioned	ADJ
gra-2157	49	14	actions	action	NOUN
gra-2157	49	15	of	of	ADP
gra-2157	49	16	angiotensinii	angiotensinii	NOUN
gra-2157	49	17	.	.	PUNCT
gra-2157	50	1	because	because	SCONJ
gra-2157	50	2	of	of	ADP
gra-2157	50	3	its	its	PRON
gra-2157	50	4	long	long	ADJ
gra-2157	50	5	half	half	ADJ
gra-2157	50	6	-	-	PUNCT
gra-2157	50	7	life	life	NOUN
gra-2157	50	8	,	,	PUNCT
gra-2157	50	9	a	a	DET
gra-2157	50	10	once	once	ADV
gra-2157	50	11	-	-	PUNCT
gra-2157	50	12	daily	daily	ADJ
gra-2157	50	13	dose	dose	NOUN
gra-2157	50	14	of	of	ADP
gra-2157	50	15	telmisartan	telmisartan	PROPN
gra-2157	50	16	has	have	AUX
gra-2157	50	17	been	be	AUX
gra-2157	50	18	found	find	VERB
gra-2157	50	19	to	to	PART
gra-2157	50	20	be	be	AUX
gra-2157	50	21	effective	effective	ADJ
gra-2157	50	22	in	in	ADP
gra-2157	50	23	minimizing	minimize	VERB
gra-2157	50	24	the	the	DET
gra-2157	50	25	elevated	elevated	ADJ
gra-2157	50	26	blood	blood	NOUN
gra-2157	50	27	pressure	pressure	NOUN
gra-2157	50	28	.	.	PUNCT
gra-2157	51	1	interestingly	interestingly	ADV
gra-2157	51	2	,	,	PUNCT
gra-2157	51	3	telmisartan	telmisartan	PROPN
gra-2157	51	4	has	have	VERB
gra-2157	51	5	the	the	DET
gra-2157	51	6	additional	additional	ADJ
gra-2157	51	7	property	property	NOUN
gra-2157	51	8	of	of	ADP
gra-2157	51	9	activating	activate	VERB
gra-2157	51	10	ppar	ppar	NOUN
gra-2157	51	11	�	�	NOUN
gra-2157	51	12	partially	partially	ADV
gra-2157	51	13	,	,	PUNCT
gra-2157	51	14	which	which	PRON
gra-2157	51	15	could	could	AUX
gra-2157	51	16	make	make	VERB
gra-2157	51	17	it	it	PRON
gra-2157	51	18	a	a	DET
gra-2157	51	19	unique	unique	ADJ
gra-2157	51	20	agent	agent	NOUN
gra-2157	51	21	in	in	ADP
gra-2157	51	22	preventing	prevent	VERB
gra-2157	51	23	cardiovascular	cardiovascular	ADJ
gra-2157	51	24	and	and	CCONJ
gra-2157	51	25	renal	renal	ADJ
gra-2157	51	26	complications	complication	NOUN
gra-2157	51	27	.	.	PUNCT
gra-2157	52	1	telmisartan	telmisartan	PROPN
gra-2157	52	2	induces	induce	VERB
gra-2157	52	3	ppar	ppar	NOUN
gra-2157	52	4	�	�	NOUN
gra-2157	52	5	activity	activity	NOUN
gra-2157	52	6	independently	independently	ADV
gra-2157	52	7	to	to	ADP
gra-2157	52	8	its	its	PRON
gra-2157	52	9	at1	at1	PROPN
gra-2157	52	10	receptor	receptor	NOUN
gra-2157	52	11	blocking	block	VERB
gra-2157	52	12	action	action	NOUN
gra-2157	52	13	.	.	PUNCT
gra-2157	53	1	patients	patient	NOUN
gra-2157	53	2	with	with	ADP
gra-2157	53	3	uncontrolled	uncontrolled	ADJ
gra-2157	53	4	type	type	NOUN
gra-2157	53	5	2	2	NUM
gra-2157	53	6	diabetes	diabetes	NOUN
gra-2157	53	7	mellitus	mellitus	NOUN
gra-2157	53	8	are	be	AUX
gra-2157	53	9	prone	prone	ADJ
gra-2157	53	10	to	to	ADP
gra-2157	53	11	hypertension	hypertension	NOUN
gra-2157	53	12	and	and	CCONJ
gra-2157	53	13	persistent	persistent	ADJ
gra-2157	53	14	proteinuria	proteinuria	NOUN
gra-2157	53	15	ranging	range	VERB
gra-2157	53	16	from	from	ADP
gra-2157	53	17	microalbuminuria	microalbuminuria	PROPN
gra-2157	53	18	to	to	ADP
gra-2157	53	19	macroalbuminuria	macroalbuminuria	PROPN
gra-2157	53	20	.	.	PUNCT
gra-2157	54	1	raas	raas	NOUN
gra-2157	54	2	over	over	ADP
gra-2157	54	3	activ	activ	PROPN
gra-2157	54	4	ation	ation	PROPN
gra-2157	54	5	plays	play	VERB
gra-2157	54	6	a	a	DET
gra-2157	54	7	central	central	ADJ
gra-2157	54	8	role	role	NOUN
gra-2157	54	9	in	in	ADP
gra-2157	54	10	the	the	DET
gra-2157	54	11	pathogenesis	pathogenesis	NOUN
gra-2157	54	12	of	of	ADP
gra-2157	54	13	diabetic	diabetic	ADJ
gra-2157	54	14	nephropathy	nephropathy	NOUN
gra-2157	54	15	.	.	PUNCT
gra-2157	55	1	telmisartan	telmisartan	PROPN
gra-2157	55	2	has	have	VERB
gra-2157	55	3	renoprotective	renoprotective	ADJ
gra-2157	55	4	effects	effect	NOUN
gra-2157	55	5	that	that	PRON
gra-2157	55	6	are	be	AUX
gra-2157	55	7	mediated	mediate	VERB
gra-2157	55	8	by	by	ADP
gra-2157	55	9	its	its	PRON
gra-2157	55	10	long	long	ADV
gra-2157	55	11	-	-	PUNCT
gra-2157	55	12	acting	act	VERB
gra-2157	55	13	at1	at1	NOUN
gra-2157	55	14	receptor	receptor	NOUN
gra-2157	55	15	blocking	block	VERB
gra-2157	55	16	action	action	NOUN
gra-2157	55	17	and	and	CCONJ
gra-2157	55	18	pparγ	pparγ	ADJ
gra-2157	55	19	partial	partial	ADJ
gra-2157	55	20	agonistic	agonistic	ADJ
gra-2157	55	21	action	action	NOUN
gra-2157	55	22	,	,	PUNCT
gra-2157	55	23	both	both	PRON
gra-2157	55	24	of	of	ADP
gra-2157	55	25	which	which	PRON
gra-2157	55	26	could	could	AUX
gra-2157	55	27	be	be	AUX
gra-2157	55	28	benecial	benecial	ADJ
gra-2157	55	29	in	in	ADP
gra-2157	55	30	affording	afford	VERB
gra-2157	55	31	renal	renal	ADJ
gra-2157	55	32	vasodilation	vasodilation	NOUN
gra-2157	55	33	,	,	PUNCT
gra-2157	55	34	preventing	prevent	VERB
gra-2157	55	35	renal	renal	ADJ
gra-2157	55	36	inammation	inammation	NOUN
gra-2157	55	37	,	,	PUNCT
gra-2157	55	38	inhibiting	inhibit	VERB
gra-2157	55	39	renal	renal	ADJ
gra-2157	55	40	oxidative	oxidative	ADJ
gra-2157	55	41	stress	stress	NOUN
gra-2157	55	42	and	and	CCONJ
gra-2157	55	43	halting	halt	VERB
gra-2157	55	44	renal	renal	ADJ
gra-2157	55	45	injury	injury	NOUN
gra-2157	55	46	in	in	ADP
gra-2157	55	47	patients	patient	NOUN
gra-2157	55	48	with	with	ADP
gra-2157	55	49	diabetic	diabetic	ADJ
gra-2157	55	50	nephropathy	nephropathy	NOUN
gra-2157	55	51	.	.	PUNCT
gra-2157	56	1	the	the	DET
gra-2157	56	2	groundbreaking	groundbreake	VERB
gra-2157	56	3	'	'	PUNCT
gra-2157	56	4	diabetics	diabetic	NOUN
gra-2157	56	5	exposed	expose	VERB
gra-2157	56	6	to	to	ADP
gra-2157	56	7	telmisartan	telmisartan	NOUN
gra-2157	56	8	and	and	CCONJ
gra-2157	56	9	enalapril	enalapril	PROPN
gra-2157	56	10	(	(	PUNCT
gra-2157	56	11	detail	detail	NOUN
gra-2157	56	12	)	)	PUNCT
gra-2157	56	13	'	'	PUNCT
gra-2157	56	14	trial	trial	NOUN
gra-2157	56	15	addressed	address	VERB
gra-2157	56	16	the	the	DET
gra-2157	56	17	long	long	ADJ
gra-2157	56	18	-	-	PUNCT
gra-2157	56	19	term	term	NOUN
gra-2157	56	20	(	(	PUNCT
gra-2157	56	21	5	5	NUM
gra-2157	56	22	years	year	NOUN
gra-2157	56	23	)	)	PUNCT
gra-2157	56	24	effects	effect	NOUN
gra-2157	56	25	of	of	ADP
gra-2157	56	26	telmisartan	telmisartan	PROPN
gra-2157	56	27	versus	versus	ADP
gra-2157	56	28	enalapril	enalapril	PROPN
gra-2157	56	29	on	on	ADP
gra-2157	56	30	renoprotection	renoprotection	NOUN
gra-2157	56	31	in	in	ADP
gra-2157	56	32	patients	patient	NOUN
gra-2157	56	33	with	with	ADP
gra-2157	56	34	hypertension	hypertension	NOUN
gra-2157	56	35	and	and	CCONJ
gra-2157	56	36	early	early	ADJ
gra-2157	56	37	type	type	NOUN
gra-2157	56	38	2	2	NUM
gra-2157	56	39	diabetic	diabetic	ADJ
gra-2157	56	40	nephropathy	nephropathy	NOUN
gra-2157	56	41	.	.	PUNCT
gra-2157	57	1	this	this	DET
gra-2157	57	2	study	study	NOUN
gra-2157	57	3	suggested	suggest	VERB
gra-2157	57	4	that	that	SCONJ
gra-2157	57	5	telmisartan	telmisartan	PROPN
gra-2157	57	6	was	be	AUX
gra-2157	57	7	not	not	PART
gra-2157	57	8	inferior	inferior	ADJ
gra-2157	57	9	to	to	PART
gra-2157	57	10	enalapril	enalapril	VERB
gra-2157	57	11	in	in	ADP
gra-2157	57	12	reducing	reduce	VERB
gra-2157	57	13	the	the	DET
gra-2157	57	14	decline	decline	NOUN
gra-2157	57	15	in	in	ADP
gra-2157	57	16	glomerular	glomerular	ADJ
gra-2157	57	17	ltration	ltration	NOUN
gra-2157	57	18	rate	rate	NOUN
gra-2157	57	19	.	.	PUNCT
gra-2157	58	1	the	the	DET
gra-2157	58	2	long	long	ADJ
gra-2157	58	3	-	-	PUNCT
gra-2157	58	4	term	term	NOUN
gra-2157	58	5	treatment	treatment	NOUN
gra-2157	58	6	with	with	ADP
gra-2157	58	7	telmisartan	telmisartan	PROPN
gra-2157	58	8	afforded	afford	VERB
gra-2157	58	9	renoprotective	renoprotective	ADJ
gra-2157	58	10	efcacy	efcacy	NOUN
gra-2157	58	11	comparable	comparable	ADJ
gra-2157	58	12	to	to	ADP
gra-2157	58	13	enalapril	enalapril	NOUN
gra-2157	58	14	in	in	ADP
gra-2157	58	15	patients	patient	NOUN
gra-2157	58	16	of	of	ADP
gra-2157	58	17	early	early	ADJ
gra-2157	58	18	-	-	PUNCT
gra-2157	58	19	type	type	NOUN
gra-2157	58	20	2	2	NUM
gra-2157	58	21	diabetic	diabetic	ADJ
gra-2157	58	22	nephropathies	nephropathy	NOUN
gra-2157	58	23	with	with	ADP
gra-2157	58	24	greater	great	ADJ
gra-2157	58	25	14tolerability	14tolerability	NUM
gra-2157	58	26	.	.	PUNCT
gra-2157	59	1	the	the	DET
gra-2157	59	2	incipient	incipient	NOUN
gra-2157	59	3	to	to	PART
gra-2157	59	4	overt	overt	VERB
gra-2157	59	5	:	:	PUNCT
gra-2157	59	6	angiotensin	angiotensin	PROPN
gra-2157	59	7	ii	ii	PROPN
gra-2157	59	8	blocker	blocker	NOUN
gra-2157	59	9	,	,	PUNCT
gra-2157	59	10	telmisartan	telmisartan	NOUN
gra-2157	59	11	,	,	PUNCT
gra-2157	59	12	investigation	investigation	NOUN
gra-2157	59	13	on	on	ADP
gra-2157	59	14	type	type	NOUN
gra-2157	59	15	2	2	NUM
gra-2157	59	16	diabetic	diabetic	ADJ
gra-2157	59	17	nephropathy	nephropathy	NOUN
gra-2157	59	18	(	(	PUNCT
gra-2157	59	19	innovation	innovation	NOUN
gra-2157	59	20	)	)	PUNCT
gra-2157	59	21	study	study	NOUN
gra-2157	59	22	determined	determine	VERB
gra-2157	59	23	whether	whether	SCONJ
gra-2157	59	24	telmisartan	telmisartan	PROPN
gra-2157	59	25	could	could	AUX
gra-2157	59	26	provide	provide	VERB
gra-2157	59	27	clinical	clinical	ADJ
gra-2157	59	28	benets	benets	PROPN
gra-2157	59	29	in	in	ADP
gra-2157	59	30	normotensive	normotensive	ADJ
gra-2157	59	31	patients	patient	NOUN
gra-2157	59	32	with	with	ADP
gra-2157	59	33	diabetes	diabetes	NOUN
gra-2157	59	34	mellitus	mellitus	NOUN
gra-2157	59	35	and	and	CCONJ
gra-2157	59	36	diabetic	diabetic	ADJ
gra-2157	59	37	nephropathy	nephropathy	NOUN
gra-2157	59	38	.	.	PUNCT
gra-2157	60	1	the	the	DET
gra-2157	60	2	patients	patient	NOUN
gra-2157	60	3	treated	treat	VERB
gra-2157	60	4	with	with	ADP
gra-2157	60	5	telmisartan	telmisartan	PROPN
gra-2157	60	6	showed	show	VERB
gra-2157	60	7	a	a	DET
gra-2157	60	8	reduction	reduction	NOUN
gra-2157	60	9	in	in	ADP
gra-2157	60	10	the	the	DET
gra-2157	60	11	transition	transition	NOUN
gra-2157	60	12	rate	rate	NOUN
gra-2157	60	13	from	from	ADP
gra-2157	60	14	microalbuminuria	microalbuminuria	PROPN
gra-2157	60	15	to	to	PART
gra-2157	60	16	overt	overt	VERB
gra-2157	60	17	nephropathy	nephropathy	NOUN
gra-2157	60	18	as	as	SCONJ
gra-2157	60	19	compared	compare	VERB
gra-2157	60	20	to	to	ADP
gra-2157	60	21	the	the	DET
gra-2157	60	22	placebo	placebo	NOUN
gra-2157	60	23	group	group	NOUN
gra-2157	60	24	.	.	PUNCT
gra-2157	61	1	moreover	moreover	ADV
gra-2157	61	2	,	,	PUNCT
gra-2157	61	3	a	a	DET
gra-2157	61	4	signicant	signicant	ADJ
gra-2157	61	5	number	number	NOUN
gra-2157	61	6	of	of	ADP
gra-2157	61	7	patients	patient	NOUN
gra-2157	61	8	in	in	ADP
gra-2157	61	9	the	the	DET
gra-2157	61	10	telmisartan	telmisartan	PROPN
gra-2157	61	11	group	group	NOUN
gra-2157	61	12	was	be	AUX
gra-2157	61	13	reverted	revert	VERB
gra-2157	61	14	to	to	ADP
gra-2157	61	15	normoalbuminuria	normoalbuminuria	PROPN
gra-2157	61	16	.	.	PUNCT
gra-2157	62	1	this	this	DET
gra-2157	62	2	clinical	clinical	ADJ
gra-2157	62	3	trial	trial	NOUN
gra-2157	62	4	strongly	strongly	ADV
gra-2157	62	5	suggested	suggest	VERB
gra-2157	62	6	that	that	SCONJ
gra-2157	62	7	telmisartan	telmisartan	PROPN
gra-2157	62	8	could	could	AUX
gra-2157	62	9	prevent	prevent	VERB
gra-2157	62	10	the	the	DET
gra-2157	62	11	progression	progression	NOUN
gra-2157	62	12	of	of	ADP
gra-2157	62	13	microalbuminuria	microalbuminuria	PROPN
gra-2157	62	14	,	,	PUNCT
gra-2157	62	15	and	and	CCONJ
gra-2157	62	16	also	also	ADV
gra-2157	62	17	induce	induce	VERB
gra-2157	62	18	remission	remission	NOUN
gra-2157	62	19	of	of	ADP
gra-2157	62	20	albuminuria	albuminuria	PROPN
gra-2157	62	21	in	in	ADP
gra-2157	62	22	normotensive	normotensive	ADJ
gra-2157	62	23	japanese	japanese	ADJ
gra-2157	62	24	patients	patient	NOUN
gra-2157	62	25	with	with	ADP
gra-2157	62	26	type	type	NOUN
gra-2157	62	27	2	2	NUM
gra-2157	62	28	diabetes	diabetes	NOUN
gra-2157	62	29	mellitus	mellitus	NOUN
gra-2157	62	30	.	.	PUNCT
gra-2157	63	1	a	a	DET
gra-2157	63	2	comparison	comparison	NOUN
gra-2157	63	3	of	of	ADP
gra-2157	63	4	telmisartan	telmisartan	PROPN
gra-2157	63	5	versus	versus	ADP
gra-2157	63	6	losartan	losartan	ADJ
gra-2157	63	7	in	in	ADP
gra-2157	63	8	hypertensive	hypertensive	ADJ
gra-2157	63	9	type	type	NOUN
gra-2157	63	10	2	2	NUM
gra-2157	63	11	diabetic	diabetic	ADJ
gra-2157	63	12	patients	patient	NOUN
gra-2157	63	13	with	with	ADP
gra-2157	63	14	overt	overt	ADJ
gra-2157	63	15	nephropathy	nephropathy	NOUN
gra-2157	63	16	(	(	PUNCT
gra-2157	63	17	amadeo	amadeo	PROPN
gra-2157	63	18	)	)	PUNCT
gra-2157	63	19	study	study	NOUN
gra-2157	63	20	compared	compare	VERB
gra-2157	63	21	the	the	DET
gra-2157	63	22	efcacy	efcacy	NOUN
gra-2157	63	23	of	of	ADP
gra-2157	63	24	telmisartan	telmisartan	NOUN
gra-2157	63	25	with	with	ADP
gra-2157	63	26	losartan	losartan	NOUN
gra-2157	63	27	for	for	ADP
gra-2157	63	28	reducing	reduce	VERB
gra-2157	63	29	urinary	urinary	ADJ
gra-2157	63	30	protein	protein	NOUN
gra-2157	63	31	-	-	PUNCT
gra-2157	63	32	to	to	ADP
gra-2157	63	33	-	-	PUNCT
gra-2157	63	34	creatinine	creatinine	NOUN
gra-2157	63	35	(	(	PUNCT
gra-2157	63	36	upc	upc	PROPN
gra-2157	63	37	)	)	PUNCT
gra-2157	63	38	ratio	ratio	NOUN
gra-2157	63	39	from	from	ADP
gra-2157	63	40	baseline	baseline	NOUN
gra-2157	63	41	after	after	ADP
gra-2157	63	42	52	52	NUM
gra-2157	63	43	weeks	week	NOUN
gra-2157	63	44	of	of	ADP
gra-2157	63	45	therapy	therapy	NOUN
gra-2157	63	46	in	in	ADP
gra-2157	63	47	hypertensive	hypertensive	ADJ
gra-2157	63	48	patients	patient	NOUN
gra-2157	63	49	with	with	ADP
gra-2157	63	50	type	type	NOUN
gra-2157	63	51	2	2	NUM
gra-2157	63	52	diabetes	diabetes	NOUN
gra-2157	63	53	mellitus	mellitus	NOUN
gra-2157	63	54	and	and	CCONJ
gra-2157	63	55	overt	overt	ADJ
gra-2157	63	56	nephropathy	nephropathy	NOUN
gra-2157	63	57	.	.	PUNCT
gra-2157	64	1	this	this	DET
gra-2157	64	2	clinical	clinical	ADJ
gra-2157	64	3	trial	trial	NOUN
gra-2157	64	4	reported	report	VERB
gra-2157	64	5	that	that	SCONJ
gra-2157	64	6	telmisartan	telmisartan	NOUN
gra-2157	64	7	-	-	PUNCT
gra-2157	64	8	based	base	VERB
gra-2157	64	9	regimen	regiman	NOUN
gra-2157	64	10	in	in	ADP
gra-2157	64	11	these	these	DET
gra-2157	64	12	patients	patient	NOUN
gra-2157	64	13	showed	show	VERB
gra-2157	64	14	a	a	DET
gra-2157	64	15	greater	great	ADJ
gra-2157	64	16	anti	anti	ADJ
gra-2157	64	17	-	-	ADJ
gra-2157	64	18	proteinuric	proteinuric	ADJ
gra-2157	64	19	effect	effect	NOUN
gra-2157	64	20	than	than	ADP
gra-2157	64	21	a	a	DET
gra-2157	64	22	losartan	losartan	NOUN
gra-2157	64	23	-	-	PUNCT
gra-2157	64	24	based	base	VERB
gra-2157	64	25	regimen	regiman	NOUN
gra-2157	64	26	at	at	ADP
gra-2157	64	27	similarly	similarly	ADV
gra-2157	64	28	achieved	achieve	VERB
gra-2157	64	29	blood	blood	NOUN
gra-2157	64	30	pressure	pressure	NOUN
gra-2157	64	31	1,15lowering	1,15lowering	NUM
gra-2157	64	32	effects	effect	NOUN
gra-2157	64	33	.	.	PUNCT
gra-2157	65	1	further	far	ADV
gra-2157	65	2	,	,	PUNCT
gra-2157	65	3	the	the	DET
gra-2157	65	4	long	long	ADJ
gra-2157	65	5	term	term	NOUN
gra-2157	65	6	renoprotective	renoprotective	ADJ
gra-2157	65	7	potential	potential	NOUN
gra-2157	65	8	of	of	ADP
gra-2157	65	9	telmisartan	telmisartan	NOUN
gra-2157	65	10	with	with	ADP
gra-2157	65	11	effects	effect	NOUN
gra-2157	65	12	of	of	ADP
gra-2157	65	13	“	"	PUNCT
gra-2157	65	14	standard	standard	NOUN
gra-2157	65	15	”	"	PUNCT
gra-2157	65	16	(	(	PUNCT
gra-2157	65	17	80	80	NUM
gra-2157	65	18	mg	mg	NOUN
gra-2157	65	19	once	once	ADV
gra-2157	65	20	daily	daily	ADV
gra-2157	65	21	)	)	PUNCT
gra-2157	65	22	versus	versus	ADP
gra-2157	65	23	“	"	PUNCT
gra-2157	65	24	high	high	ADJ
gra-2157	65	25	”	"	PUNCT
gra-2157	65	26	(	(	PUNCT
gra-2157	65	27	80	80	NUM
gra-2157	65	28	mg	mg	NOUN
gra-2157	65	29	twice	twice	ADV
gra-2157	65	30	daily	daily	ADV
gra-2157	65	31	)	)	PUNCT
gra-2157	65	32	doses	dose	NOUN
gra-2157	65	33	of	of	ADP
gra-2157	65	34	telmisartan	telmisartan	PROPN
gra-2157	65	35	in	in	ADP
gra-2157	65	36	hypertensive	hypertensive	ADJ
gra-2157	65	37	patients	patient	NOUN
gra-2157	65	38	without	without	ADP
gra-2157	65	39	diabetes	diabetes	NOUN
gra-2157	65	40	with	with	ADP
gra-2157	65	41	biopsy	biopsy	NOUN
gra-2157	65	42	-	-	PUNCT
gra-2157	65	43	proven	prove	VERB
gra-2157	65	44	chronic	chronic	ADJ
gra-2157	65	45	proteinuric	proteinuric	ADJ
gra-2157	65	46	nephropathies	nephropathy	NOUN
gra-2157	65	47	was	be	AUX
gra-2157	65	48	carried	carry	VERB
gra-2157	65	49	out	out	ADP
gra-2157	65	50	by	by	ADP
gra-2157	65	51	aranda	aranda	PROPN
gra-2157	65	52	16et	16et	PROPN
gra-2157	65	53	al	al	PROPN
gra-2157	65	54	.	.	PROPN
gra-2157	65	55	.	.	PUNCT
gra-2157	66	1	the	the	DET
gra-2157	66	2	study	study	NOUN
gra-2157	66	3	was	be	AUX
gra-2157	66	4	carried	carry	VERB
gra-2157	66	5	out	out	ADP
gra-2157	66	6	in	in	ADP
gra-2157	66	7	78	78	NUM
gra-2157	66	8	patients	patient	NOUN
gra-2157	66	9	.	.	PUNCT
gra-2157	67	1	at	at	ADP
gra-2157	67	2	the	the	DET
gra-2157	67	3	end	end	NOUN
gra-2157	67	4	of	of	ADP
gra-2157	67	5	the	the	DET
gra-2157	67	6	study	study	NOUN
gra-2157	67	7	,	,	PUNCT
gra-2157	67	8	blood	blood	NOUN
gra-2157	67	9	pressure	pressure	NOUN
gra-2157	67	10	control	control	NOUN
gra-2157	67	11	did	do	AUX
gra-2157	67	12	not	not	PART
gra-2157	67	13	differ	differ	VERB
gra-2157	67	14	between	between	ADP
gra-2157	67	15	groups	group	NOUN
gra-2157	67	16	.	.	PUNCT
gra-2157	68	1	in	in	ADP
gra-2157	68	2	the	the	DET
gra-2157	68	3	group	group	NOUN
gra-2157	68	4	administered	administer	VERB
gra-2157	68	5	telmisartan	telmisartan	NOUN
gra-2157	68	6	,	,	PUNCT
gra-2157	68	7	80	80	NUM
gra-2157	68	8	mg	mg	ADP
gra-2157	68	9	once	once	ADV
gra-2157	68	10	daily	daily	ADV
gra-2157	68	11	,	,	PUNCT
gra-2157	68	12	serum	serum	NOUN
gra-2157	68	13	creatinine	creatinine	NOUN
gra-2157	68	14	level	level	NOUN
gra-2157	68	15	increased	increase	VERB
gra-2157	68	16	from	from	ADP
gra-2157	68	17	1.6	1.6	NUM
gra-2157	68	18	±	±	NUM
gra-2157	68	19	0.6	0.6	NUM
gra-2157	68	20	to	to	ADP
gra-2157	68	21	2.7±0.9	2.7±0.9	NUM
gra-2157	68	22	mg	mg	PROPN
gra-2157	68	23	/	/	SYM
gra-2157	68	24	dl	dl	PROPN
gra-2157	68	25	(	(	PUNCT
gra-2157	68	26	141	141	NUM
gra-2157	68	27	±52	±52	PROPN
gra-2157	68	28	to	to	ADP
gra-2157	68	29	239±80	239±80	PROPN
gra-2157	68	30	µmol	µmol	NOUN
gra-2157	68	31	/	/	SYM
gra-2157	68	32	l	l	NOUN
gra-2157	68	33	)	)	PUNCT
gra-2157	68	34	,	,	PUNCT
gra-2157	68	35	and	and	CCONJ
gra-2157	68	36	estimated	estimate	VERB
gra-2157	68	37	creatinine	creatinine	NOUN
gra-2157	68	38	clearance	clearance	NOUN
gra-2157	68	39	declined	decline	VERB
gra-2157	68	40	from	from	ADP
gra-2157	68	41	68	68	NUM
gra-2157	68	42	±30	±30	ADV
gra-2157	68	43	to	to	ADP
gra-2157	68	44	50	50	NUM
gra-2157	68	45	±34	±34	NOUN
gra-2157	68	46	ml	ml	NOUN
gra-2157	68	47	/	/	SYM
gra-2157	68	48	min	min	PROPN
gra-2157	69	1	(	(	PUNCT
gra-2157	69	2	1.13±0.50	1.13±0.50	NUM
gra-2157	69	3	to	to	ADP
gra-2157	69	4	0.83	0.83	NUM
gra-2157	69	5	±	±	NUM
gra-2157	69	6	0.57	0.57	NUM
gra-2157	69	7	ml	ml	NOUN
gra-2157	69	8	/	/	SYM
gra-2157	69	9	s	s	NOUN
gra-2157	69	10	)	)	PUNCT
gra-2157	69	11	,	,	PUNCT
gra-2157	69	12	whereas	whereas	SCONJ
gra-2157	69	13	in	in	SCONJ
gra-2157	69	14	that	that	PRON
gra-2157	69	15	administered	administer	VERB
gra-2157	69	16	80	80	NUM
gra-2157	69	17	mg	mg	NOUN
gra-2157	69	18	twice	twice	ADV
gra-2157	69	19	daily	daily	ADV
gra-2157	69	20	,	,	PUNCT
gra-2157	69	21	serum	serum	NOUN
gra-2157	69	22	creatinine	creatinine	NOUN
gra-2157	69	23	(	(	PUNCT
gra-2157	69	24	1.6±0.7	1.6±0.7	NUM
gra-2157	69	25	to	to	PART
gra-2157	69	26	1.6±0.8	1.6±0.8	NUM
gra-2157	69	27	mg	mg	PROPN
gra-2157	69	28	/	/	SYM
gra-2157	69	29	dl	dl	PROPN
gra-2157	70	1	[	[	X
gra-2157	70	2	141±62	141±62	NUM
gra-2157	70	3	to	to	ADP
gra-2157	70	4	141±	141±	PROPN
gra-2157	70	5	71	71	NUM
gra-2157	70	6	µmol	µmol	NOUN
gra-2157	70	7	/	/	SYM
gra-2157	70	8	l	l	NOUN
gra-2157	70	9	]	]	PUNCT
gra-2157	70	10	)	)	PUNCT
gra-2157	70	11	and	and	CCONJ
gra-2157	70	12	estimated	estimate	VERB
gra-2157	70	13	creatinine	creatinine	NOUN
gra-2157	70	14	clearance	clearance	NOUN
gra-2157	70	15	values	value	NOUN
gra-2157	70	16	(	(	PUNCT
gra-2157	70	17	67±38	67±38	NOUN
gra-2157	70	18	to	to	ADP
gra-2157	70	19	74±38	74±38	PROPN
gra-2157	70	20	ml	ml	NOUN
gra-2157	70	21	/	/	SYM
gra-2157	70	22	min	min	NOUN
gra-2157	70	23	[	[	X
gra-2157	70	24	1.12	1.12	NUM
gra-2157	70	25	±0.63	±0.63	PROPN
gra-2157	70	26	to	to	ADP
gra-2157	70	27	1.23	1.23	NUM
gra-2157	70	28	±	±	NUM
gra-2157	70	29	0.63	0.63	NUM
gra-2157	70	30	ml	ml	NOUN
gra-2157	70	31	/	/	SYM
gra-2157	70	32	s	s	PROPN
gra-2157	70	33	]	]	PUNCT
gra-2157	70	34	)	)	PUNCT
gra-2157	70	35	did	do	AUX
gra-2157	70	36	not	not	PART
gra-2157	70	37	change	change	VERB
gra-2157	70	38	during	during	ADP
gra-2157	70	39	the	the	DET
gra-2157	70	40	study	study	NOUN
gra-2157	70	41	.	.	PUNCT
gra-2157	71	1	the	the	DET
gra-2157	71	2	decrease	decrease	NOUN
gra-2157	71	3	in	in	ADP
gra-2157	71	4	proteinuria	proteinuria	NOUN
gra-2157	71	5	was	be	AUX
gra-2157	71	6	more	more	ADV
gra-2157	71	7	pronounced	pronounced	ADJ
gra-2157	71	8	(	(	PUNCT
gra-2157	71	9	p<0.01	p<0.01	PROPN
gra-2157	71	10	)	)	PUNCT
gra-2157	71	11	in	in	ADP
gra-2157	71	12	patients	patient	NOUN
gra-2157	71	13	administered	administer	VERB
gra-2157	71	14	the	the	DET
gra-2157	71	15	high	high	ADJ
gra-2157	71	16	dose	dose	NOUN
gra-2157	71	17	of	of	ADP
gra-2157	71	18	telmisartan	telmisartan	PROPN
gra-2157	71	19	compared	compare	VERB
gra-2157	71	20	with	with	ADP
gra-2157	71	21	those	those	PRON
gra-2157	71	22	treated	treat	VERB
gra-2157	71	23	with	with	ADP
gra-2157	71	24	the	the	DET
gra-2157	71	25	standard	standard	ADJ
gra-2157	71	26	dose	dose	NOUN
gra-2157	71	27	.	.	PUNCT
gra-2157	72	1	it	it	PRON
gra-2157	72	2	was	be	AUX
gra-2157	72	3	concluded	conclude	VERB
gra-2157	72	4	that	that	SCONJ
gra-2157	72	5	long	long	ADJ
gra-2157	72	6	-	-	PUNCT
gra-2157	72	7	term	term	NOUN
gra-2157	72	8	administration	administration	NOUN
gra-2157	72	9	of	of	ADP
gra-2157	72	10	high	high	ADJ
gra-2157	72	11	doses	dose	NOUN
gra-2157	72	12	of	of	ADP
gra-2157	72	13	telmisartan	telmisartan	PROPN
gra-2157	72	14	seems	seem	VERB
gra-2157	72	15	to	to	PART
gra-2157	72	16	improve	improve	VERB
gra-2157	72	17	the	the	DET
gra-2157	72	18	efcacy	efcacy	NOUN
gra-2157	72	19	of	of	ADP
gra-2157	72	20	the	the	DET
gra-2157	72	21	drug	drug	NOUN
gra-2157	72	22	to	to	PART
gra-2157	72	23	decrease	decrease	VERB
gra-2157	72	24	proteinuria	proteinuria	NOUN
gra-2157	72	25	and	and	CCONJ
gra-2157	72	26	slow	slow	VERB
gra-2157	72	27	the	the	DET
gra-2157	72	28	progression	progression	NOUN
gra-2157	72	29	to	to	PART
gra-2157	72	30	end	end	VERB
gra-2157	72	31	-	-	PUNCT
gra-2157	72	32	stage	stage	NOUN
gra-2157	72	33	renal	renal	ADJ
gra-2157	72	34	failure	failure	NOUN
gra-2157	72	35	in	in	ADP
gra-2157	72	36	nondiabetic	nondiabetic	ADJ
gra-2157	72	37	16hypertensive	16hypertensive	NUM
gra-2157	72	38	renal	renal	ADJ
gra-2157	72	39	disease	disease	NOUN
gra-2157	72	40	.	.	PUNCT
gra-2157	73	1	attenuation	attenuation	NOUN
gra-2157	73	2	of	of	ADP
gra-2157	73	3	the	the	DET
gra-2157	73	4	renal	renal	ADJ
gra-2157	73	5	damage	damage	NOUN
gra-2157	73	6	of	of	ADP
gra-2157	73	7	diabetic	diabetic	ADJ
gra-2157	73	8	nephropathy	nephropathy	NOUN
gra-2157	73	9	through	through	ADP
gra-2157	73	10	the	the	DET
gra-2157	73	11	inhibition	inhibition	NOUN
gra-2157	73	12	of	of	ADP
gra-2157	73	13	at1r	at1r	PROPN
gra-2157	73	14	-	-	PUNCT
gra-2157	73	15	adipor1	adipor1	NOUN
gra-2157	73	16	heterodimerization	heterodimerization	NOUN
gra-2157	73	17	and	and	CCONJ
gra-2157	73	18	alleviation	alleviation	NOUN
gra-2157	73	19	of	of	ADP
gra-2157	73	20	downstream	downstream	ADJ
gra-2157	73	21	inammatory	inammatory	ADJ
gra-2157	73	22	responses	response	NOUN
gra-2157	73	23	and	and	CCONJ
gra-2157	73	24	cell	cell	NOUN
gra-2157	73	25	apoptosis	apoptosis	NOUN
gra-2157	73	26	by	by	ADP
gra-2157	73	27	telmisartan	telmisartan	PROPN
gra-2157	73	28	has	have	AUX
gra-2157	73	29	also	also	ADV
gra-2157	73	30	been	be	AUX
gra-2157	73	31	proposed	propose	VERB
gra-2157	73	32	to	to	PART
gra-2157	73	33	be	be	AUX
gra-2157	73	34	3another	3another	NUM
gra-2157	73	35	mechanism	mechanism	NOUN
gra-2157	73	36	of	of	ADP
gra-2157	73	37	renoprotective	renoprotective	ADJ
gra-2157	73	38	action	action	NOUN
gra-2157	73	39	of	of	ADP
gra-2157	73	40	telmisartan	telmisartan	PROPN
gra-2157	73	41	.	.	PUNCT
gra-2157	74	1	simultaneously	simultaneously	ADV
gra-2157	74	2	,	,	PUNCT
gra-2157	74	3	the	the	DET
gra-2157	74	4	telmisartan	telmisartan	NOUN
gra-2157	74	5	versus	versus	ADP
gra-2157	74	6	ramipril	ramipril	PROPN
gra-2157	74	7	in	in	ADP
gra-2157	74	8	renal	renal	ADJ
gra-2157	74	9	®	®	NOUN
gra-2157	74	10	endothelium	endothelium	NOUN
gra-2157	74	11	dysfunction	dysfunction	NOUN
gra-2157	74	12	(	(	PUNCT
gra-2157	74	13	trendy	trendy	ADJ
gra-2157	74	14	)	)	PUNCT
gra-2157	74	15	study	study	NOUN
gra-2157	74	16	showed	show	VERB
gra-2157	74	17	that	that	SCONJ
gra-2157	74	18	treatment	treatment	NOUN
gra-2157	74	19	with	with	ADP
gra-2157	74	20	telmisartan	telmisartan	NOUN
gra-2157	74	21	or	or	CCONJ
gra-2157	74	22	ramipril	ramipril	VERB
gra-2157	74	23	for	for	ADP
gra-2157	74	24	9	9	NUM
gra-2157	74	25	weeks	week	NOUN
gra-2157	74	26	signicantly	signicantly	ADV
gra-2157	74	27	improved	improve	VERB
gra-2157	74	28	(	(	PUNCT
gra-2157	74	29	p	p	X
gra-2157	74	30	<	<	X
gra-2157	74	31	0.001	0.001	NUM
gra-2157	74	32	)	)	PUNCT
gra-2157	74	33	the	the	DET
gra-2157	74	34	response	response	NOUN
gra-2157	74	35	of	of	ADP
gra-2157	74	36	the	the	DET
gra-2157	74	37	renal	renal	ADJ
gra-2157	74	38	vasculature	vasculature	NOUN
gra-2157	74	39	to	to	ADP
gra-2157	74	40	nitric	nitric	ADJ
gra-2157	74	41	oxide	oxide	NOUN
gra-2157	74	42	,	,	PUNCT
gra-2157	74	43	an	an	DET
gra-2157	74	44	indicator	indicator	NOUN
gra-2157	74	45	of	of	ADP
gra-2157	74	46	basal	basal	ADJ
gra-2157	74	47	nitric	nitric	ADJ
gra-2157	74	48	oxide	oxide	NOUN
gra-2157	74	49	activity	activity	NOUN
gra-2157	74	50	and	and	CCONJ
gra-2157	74	51	thereby	thereby	ADV
gra-2157	74	52	of	of	ADP
gra-2157	74	53	endothelial	endothelial	ADJ
gra-2157	74	54	function	function	NOUN
gra-2157	74	55	of	of	ADP
gra-2157	74	56	the	the	DET
gra-2157	74	57	renal	renal	ADJ
gra-2157	74	58	vasculature	vasculature	NOUN
gra-2157	74	59	.	.	PUNCT
gra-2157	75	1	the	the	DET
gra-2157	75	2	magnitude	magnitude	NOUN
gra-2157	75	3	of	of	ADP
gra-2157	75	4	the	the	DET
gra-2157	75	5	effect	effect	NOUN
gra-2157	75	6	of	of	ADP
gra-2157	75	7	telmisartan	telmisartan	PROPN
gra-2157	75	8	appeared	appear	VERB
gra-2157	75	9	somewhat	somewhat	ADV
gra-2157	75	10	17greater	17greater	NUM
gra-2157	75	11	than	than	ADP
gra-2157	75	12	that	that	PRON
gra-2157	75	13	of	of	ADP
gra-2157	75	14	ramipril	ramipril	NOUN
gra-2157	75	15	.	.	PUNCT
gra-2157	76	1	conclusion	conclusion	NOUN
gra-2157	76	2	an	an	DET
gra-2157	76	3	essential	essential	ADJ
gra-2157	76	4	component	component	NOUN
gra-2157	76	5	of	of	ADP
gra-2157	76	6	the	the	DET
gra-2157	76	7	management	management	NOUN
gra-2157	76	8	of	of	ADP
gra-2157	76	9	diabetic	diabetic	ADJ
gra-2157	76	10	patients	patient	NOUN
gra-2157	76	11	,	,	PUNCT
gra-2157	76	12	especially	especially	ADV
gra-2157	76	13	those	those	PRON
gra-2157	76	14	with	with	ADP
gra-2157	76	15	other	other	ADJ
gra-2157	76	16	risk	risk	NOUN
gra-2157	76	17	factors	factor	NOUN
gra-2157	76	18	such	such	ADJ
gra-2157	76	19	as	as	ADP
gra-2157	76	20	neph	neph	NOUN
gra-2157	76	21	ropathy	ropathy	ADJ
gra-2157	76	22	,	,	PUNCT
gra-2157	76	23	is	be	AUX
gra-2157	76	24	the	the	DET
gra-2157	76	25	control	control	NOUN
gra-2157	76	26	of	of	ADP
gra-2157	76	27	blood	blood	NOUN
gra-2157	76	28	pressure	pressure	NOUN
gra-2157	76	29	to	to	PART
gra-2157	76	30	prevent	prevent	VERB
gra-2157	76	31	cardio	cardio	NOUN
gra-2157	76	32	v	v	ADP
gra-2157	76	33	ascular	ascular	ADJ
gra-2157	76	34	events	event	NOUN
gra-2157	76	35	and	and	CCONJ
gra-2157	76	36	premature	premature	ADJ
gra-2157	76	37	death	death	NOUN
gra-2157	76	38	.	.	PUNCT
gra-2157	77	1	blood	blood	NOUN
gra-2157	77	2	pressure	pressure	NOUN
gra-2157	77	3	targets	target	NOUN
gra-2157	77	4	are	be	AUX
gra-2157	77	5	in	in	ADP
gra-2157	77	6	most	most	ADJ
gra-2157	77	7	cases	case	NOUN
gra-2157	77	8	not	not	PART
gra-2157	77	9	being	be	AUX
gra-2157	77	10	met	meet	VERB
gra-2157	77	11	and	and	CCONJ
gra-2157	77	12	further	far	ADV
gra-2157	77	13	complicating	complicate	VERB
gra-2157	77	14	the	the	DET
gra-2157	77	15	disease	disease	NOUN
gra-2157	77	16	state	state	NOUN
gra-2157	77	17	.	.	PUNCT
gra-2157	78	1	telmisartan	telmisartan	PROPN
gra-2157	78	2	seems	seem	VERB
gra-2157	78	3	to	to	PART
gra-2157	78	4	be	be	AUX
gra-2157	78	5	an	an	DET
gra-2157	78	6	ideal	ideal	ADJ
gra-2157	78	7	drug	drug	NOUN
gra-2157	78	8	for	for	ADP
gra-2157	78	9	such	such	DET
gra-2157	78	10	a	a	DET
gra-2157	78	11	situation	situation	NOUN
gra-2157	78	12	.	.	PUNCT
gra-2157	79	1	telmisartan	telmisartan	PROPN
gra-2157	79	2	posses	posse	NOUN
gra-2157	79	3	dual	dual	ADJ
gra-2157	79	4	action	action	NOUN
gra-2157	79	5	of	of	ADP
gra-2157	79	6	cardioprotection	cardioprotection	NOUN
gra-2157	79	7	along	along	ADP
gra-2157	79	8	with	with	ADP
gra-2157	79	9	with	with	ADP
gra-2157	79	10	underlying	underlie	VERB
gra-2157	79	11	long	long	ADJ
gra-2157	79	12	term	term	NOUN
gra-2157	79	13	renoprotective	renoprotective	ADJ
gra-2157	79	14	action	action	NOUN
gra-2157	79	15	by	by	ADP
gra-2157	79	16	virtue	virtue	NOUN
gra-2157	79	17	of	of	ADP
gra-2157	79	18	inhibiting	inhibit	VERB
gra-2157	79	19	at	at	ADP
gra-2157	79	20	ii	ii	NOUN
gra-2157	79	21	and	and	CCONJ
gra-2157	79	22	induces	induce	VERB
gra-2157	79	23	pparγ	pparγ	ADJ
gra-2157	79	24	activity	activity	NOUN
gra-2157	79	25	.	.	PUNCT
gra-2157	80	1	thus	thus	ADV
gra-2157	80	2	,	,	PUNCT
gra-2157	80	3	it	it	PRON
gra-2157	80	4	seems	seem	VERB
gra-2157	80	5	logical	logical	ADJ
gra-2157	80	6	to	to	PART
gra-2157	80	7	adopt	adopt	VERB
gra-2157	80	8	telmisartan	telmisartan	PROPN
gra-2157	80	9	in	in	ADP
gra-2157	80	10	therapy	therapy	NOUN
gra-2157	80	11	for	for	ADP
gra-2157	80	12	the	the	DET
gra-2157	80	13	better	well	ADJ
gra-2157	80	14	management	management	NOUN
gra-2157	80	15	of	of	ADP
gra-2157	80	16	diabetes	diabete	NOUN
gra-2157	80	17	complicated	complicate	VERB
gra-2157	80	18	with	with	ADP
gra-2157	80	19	hypertension	hypertension	NOUN
gra-2157	80	20	and	and	CCONJ
gra-2157	80	21	diabetic	diabetic	ADJ
gra-2157	80	22	nephropathy	nephropathy	NOUN
gra-2157	80	23	.	.	PUNCT
gra-2157	81	1	references	reference	NOUN
gra-2157	81	2	1	1	NUM
gra-2157	81	3	.	.	PUNCT
gra-2157	82	1	balakumar	balakumar	PROPN
gra-2157	82	2	p	p	PROPN
gra-2157	82	3	,	,	PUNCT
gra-2157	82	4	k.	k.	PROPN
gra-2157	82	5	bishnoi	bishnoi	PROPN
gra-2157	82	6	h	h	PROPN
gra-2157	82	7	,	,	PUNCT
gra-2157	82	8	mahadevan	mahadevan	PROPN
gra-2157	82	9	n.	n.	PROPN
gra-2157	82	10	telmisartan	telmisartan	PROPN
gra-2157	82	11	in	in	ADP
gra-2157	82	12	the	the	DET
gra-2157	82	13	management	management	NOUN
gra-2157	82	14	of	of	ADP
gra-2157	82	15	diabetic	diabetic	ADJ
gra-2157	82	16	nephropathy	nephropathy	NOUN
gra-2157	82	17	:	:	PUNCT
gra-2157	82	18	a	a	DET
gra-2157	82	19	contemporary	contemporary	ADJ
gra-2157	82	20	view	view	NOUN
gra-2157	82	21	.	.	PUNCT
gra-2157	83	1	curr	curr	PROPN
gra-2157	83	2	diabetes	diabetes	PROPN
gra-2157	83	3	rev	rev	VERB
gra-2157	83	4	.	.	PROPN
gra-2157	84	1	2012;8(3):183	2012;8(3):183	NUM
gra-2157	84	2	-	-	SYM
gra-2157	84	3	190	190	NUM
gra-2157	84	4	.	.	PUNCT
gra-2157	85	1	doi:10.2174/157339912800563972	doi:10.2174/157339912800563972	VERB
gra-2157	85	2	2	2	NUM
gra-2157	85	3	.	.	NUM
gra-2157	85	4	fukami	fukami	PROPN
gra-2157	85	5	k	k	PROPN
gra-2157	85	6	,	,	PUNCT
gra-2157	85	7	yamagishi	yamagishi	PROPN
gra-2157	85	8	s.	s.	PROPN
gra-2157	86	1	an	an	DET
gra-2157	86	2	overview	overview	NOUN
gra-2157	86	3	on	on	ADP
gra-2157	86	4	diabetic	diabetic	ADJ
gra-2157	86	5	nephropathy	nephropathy	NOUN
gra-2157	86	6	.	.	PUNCT
gra-2157	87	1	nutr	nutr	PROPN
gra-2157	87	2	ther	ther	PROPN
gra-2157	87	3	interv	interv	VERB
gra-2157	87	4	diabetes	diabete	VERB
gra-2157	87	5	metab	metab	ADJ
gra-2157	87	6	syndr	syndr	NOUN
gra-2157	87	7	.	.	PUNCT
gra-2157	88	1	2018:125	2018:125	NUM
gra-2157	88	2	-	-	PUNCT
gra-2157	88	3	137	137	NUM
gra-2157	88	4	.	.	PUNCT
gra-2157	89	1	doi:10.1016	doi:10.1016	PROPN
gra-2157	89	2	/	/	SYM
gra-2157	89	3	b978	b978	PROPN
gra-2157	89	4	-	-	PUNCT
gra-2157	89	5	0	0	NUM
gra-2157	89	6	-	-	PUNCT
gra-2157	89	7	12	12	NUM
gra-2157	89	8	-	-	PUNCT
gra-2157	89	9	8120194.00010	8120194.00010	NUM
gra-2157	89	10	-	-	PUNCT
gra-2157	89	11	6	6	NUM
gra-2157	89	12	3	3	NUM
gra-2157	89	13	.	.	PUNCT
gra-2157	89	14	zha	zha	PROPN
gra-2157	89	15	d	d	PROPN
gra-2157	89	16	,	,	PUNCT
gra-2157	89	17	yao	yao	PROPN
gra-2157	89	18	t	t	PROPN
gra-2157	89	19	,	,	PUNCT
gra-2157	89	20	bao	bao	PROPN
gra-2157	89	21	l	l	PROPN
gra-2157	89	22	,	,	PUNCT
gra-2157	89	23	gao	gao	PROPN
gra-2157	89	24	p	p	X
gra-2157	89	25	,	,	PUNCT
gra-2157	89	26	wu	wu	PROPN
gra-2157	89	27	x.	x.	PROPN
gra-2157	89	28	telmisartan	telmisartan	PROPN
gra-2157	89	29	attenuates	attenuate	VERB
gra-2157	89	30	diabetic	diabetic	ADJ
gra-2157	89	31	nephropathy	nephropathy	ADJ
gra-2157	89	32	progression	progression	NOUN
gra-2157	89	33	by	by	ADP
gra-2157	89	34	inhibiting	inhibit	VERB
gra-2157	89	35	the	the	DET
gra-2157	89	36	dimerization	dimerization	NOUN
gra-2157	89	37	of	of	ADP
gra-2157	89	38	angiotensin	angiotensin	NOUN
gra-2157	89	39	type-1	type-1	PROPN
gra-2157	89	40	receptor	receptor	NOUN
gra-2157	89	41	and	and	CCONJ
gra-2157	89	42	adiponectin	adiponectin	NOUN
gra-2157	89	43	receptor-1	receptor-1	NUM
gra-2157	89	44	.	.	PUNCT
gra-2157	90	1	life	life	PROPN
gra-2157	90	2	sci	sci	PROPN
gra-2157	90	3	.	.	PUNCT
gra-2157	91	1	2019;221(august	2019;221(august	NUM
gra-2157	91	2	2018):109	2018):109	NUM
gra-2157	91	3	-	-	SYM
gra-2157	91	4	120	120	NUM
gra-2157	91	5	.	.	PUNCT
gra-2157	92	1	doi:10.1016	doi:10.1016	PROPN
gra-2157	92	2	/	/	SYM
gra-2157	92	3	j.lfs.2019.01.044	j.lfs.2019.01.044	PROPN
gra-2157	92	4	4	4	NUM
gra-2157	92	5	.	.	PUNCT
gra-2157	93	1	van	van	PROPN
gra-2157	93	2	buren	buren	PROPN
gra-2157	93	3	pn	pn	PROPN
gra-2157	93	4	,	,	PUNCT
gra-2157	93	5	toto	toto	PROPN
gra-2157	93	6	r.	r.	PROPN
gra-2157	93	7	hypertension	hypertension	PROPN
gra-2157	93	8	in	in	ADP
gra-2157	93	9	diabetic	diabetic	ADJ
gra-2157	93	10	nephropathy	nephropathy	NOUN
gra-2157	93	11	:	:	PUNCT
gra-2157	93	12	epidemiology	epidemiology	NOUN
gra-2157	93	13	,	,	PUNCT
gra-2157	93	14	mechanisms	mechanism	NOUN
gra-2157	93	15	,	,	PUNCT
gra-2157	93	16	and	and	CCONJ
gra-2157	93	17	management	management	NOUN
gra-2157	93	18	.	.	PUNCT
gra-2157	94	1	adv	adv	PROPN
gra-2157	94	2	chronic	chronic	ADJ
gra-2157	94	3	kidney	kidney	PROPN
gra-2157	94	4	dis	dis	PROPN
gra-2157	94	5	.	.	PUNCT
gra-2157	95	1	2011;18(1):28	2011;18(1):28	PROPN
gra-2157	95	2	-	-	PUNCT
gra-2157	95	3	41	41	NUM
gra-2157	95	4	.	.	PUNCT
gra-2157	96	1	doi:10.1053	doi:10.1053	PROPN
gra-2157	96	2	/	/	SYM
gra-2157	96	3	j.ackd.2010.10.003	j.ackd.2010.10.003	ADJ
gra-2157	96	4	5	5	NUM
gra-2157	96	5	.	.	PUNCT
gra-2157	97	1	pitrosch	pitrosch	PROPN
gra-2157	97	2	f	f	X
gra-2157	97	3	,	,	PUNCT
gra-2157	97	4	herbrig	herbrig	PROPN
gra-2157	97	5	k	k	PROPN
gra-2157	97	6	,	,	PUNCT
gra-2157	97	7	kinder	kind	ADJ
gra-2157	97	8	b	b	NOUN
gra-2157	97	9	,	,	PUNCT
gra-2157	97	10	passauer	passauer	PROPN
gra-2157	97	11	j	j	PROPN
gra-2157	97	12	,	,	PUNCT
gra-2157	97	13	fisher	fisher	PROPN
gra-2157	97	14	s	s	PART
gra-2157	97	15	gp	gp	NOUN
gra-2157	97	16	.	.	PUNCT
gra-2157	98	1	rosiglitazone	rosiglitazone	NOUN
gra-2157	98	2	improves	improve	VERB
gra-2157	98	3	glomerular	glomerular	ADJ
gra-2157	98	4	hyperlteration	hyperlteration	NOUN
gra-2157	98	5	,	,	PUNCT
gra-2157	98	6	renal	renal	ADJ
gra-2157	98	7	endothelial	endothelial	ADJ
gra-2157	98	8	dysfunction	dysfunction	NOUN
gra-2157	98	9	and	and	CCONJ
gra-2157	98	10	microalbuminuria	microalbuminuria	NOUN
gra-2157	98	11	of	of	ADP
gra-2157	98	12	incipient	incipient	ADJ
gra-2157	98	13	diabetic	diabetic	ADJ
gra-2157	98	14	nephropathy	nephropathy	NOUN
gra-2157	98	15	in	in	ADP
gra-2157	98	16	patients	patient	NOUN
gra-2157	98	17	.	.	PUNCT
gra-2157	99	1	diabetes	diabetes	NOUN
gra-2157	99	2	.	.	PUNCT
gra-2157	100	1	2005;54:2206–11	2005;54:2206–11	NUM
gra-2157	100	2	.	.	NOUN
gra-2157	100	3	6	6	NUM
gra-2157	100	4	.	.	PUNCT
gra-2157	100	5	nagai	nagai	PROPN
gra-2157	100	6	t	t	PROPN
gra-2157	100	7	,	,	PUNCT
gra-2157	100	8	tomizawa	tomizawa	PROPN
gra-2157	100	9	t	t	PROPN
gra-2157	100	10	mm	mm	PROPN
gra-2157	100	11	.	.	PUNCT
gra-2157	101	1	effect	effect	NOUN
gra-2157	101	2	of	of	ADP
gra-2157	101	3	bezabrate	bezabrate	NOUN
gra-2157	101	4	or	or	CCONJ
gra-2157	101	5	pravastatin	pravastatin	NOUN
gra-2157	101	6	on	on	ADP
gra-2157	101	7	serum	serum	NOUN
gra-2157	101	8	lipid	lipid	NOUN
gra-2157	101	9	level	level	NOUN
gra-2157	101	10	and	and	CCONJ
gra-2157	101	11	albuminuria	albuminuria	NOUN
gra-2157	101	12	in	in	ADP
gra-2157	101	13	niddm	niddm	PROPN
gra-2157	101	14	patients	patient	NOUN
gra-2157	101	15	.	.	PUNCT
gra-2157	102	1	j	j	PROPN
gra-2157	102	2	atheroscler	atheroscler	PROPN
gra-2157	102	3	thromb	thromb	PROPN
gra-2157	102	4	.	.	PUNCT
gra-2157	103	1	2000;7:91–6	2000;7:91–6	NOUN
gra-2157	103	2	.	.	PUNCT
gra-2157	104	1	7	7	X
gra-2157	104	2	.	.	X
gra-2157	104	3	bonnet	bonnet	NOUN
gra-2157	104	4	f	f	PROPN
gra-2157	104	5	cm	cm	PROPN
gra-2157	104	6	.	.	PUNCT
gra-2157	105	1	potential	potential	ADJ
gra-2157	105	2	inuence	inuence	PROPN
gra-2157	105	3	of	of	ADP
gra-2157	105	4	lipids	lipid	NOUN
gra-2157	105	5	in	in	ADP
gra-2157	105	6	diabetic	diabetic	ADJ
gra-2157	105	7	nephropathy	nephropathy	NOUN
gra-2157	105	8	:	:	PUNCT
gra-2157	105	9	insights	insight	NOUN
gra-2157	105	10	volume-9	volume-9	NUM
gra-2157	105	11	,	,	PUNCT
gra-2157	105	12	issue-3	issue-3	NUM
gra-2157	105	13	,	,	PUNCT
gra-2157	105	14	march-2020	march-2020	ADJ
gra-2157	105	15	•	•	NOUN
gra-2157	105	16	print	print	NOUN
gra-2157	105	17	issn	issn	PROPN
gra-2157	105	18	no	no	NOUN
gra-2157	105	19	.	.	PROPN
gra-2157	105	20	2277	2277	NUM
gra-2157	105	21	8160	8160	NUM
gra-2157	105	22	•	•	NOUN
gra-2157	105	23	doi	doi	NOUN
gra-2157	105	24	:	:	PUNCT
gra-2157	105	25	10.36106	10.36106	NUM
gra-2157	105	26	/	/	SYM
gra-2157	105	27	gjra	gjra	NOUN
gra-2157	105	28	x	x	SYM
gra-2157	105	29	39gjra	39gjra	PROPN
gra-2157	105	30	global	global	ADJ
gra-2157	105	31	journal	journal	PROPN
gra-2157	105	32	for	for	ADP
gra-2157	105	33	research	research	NOUN
gra-2157	105	34	analysis	analysis	NOUN
gra-2157	105	35	from	from	ADP
gra-2157	105	36	experimental	experimental	ADJ
gra-2157	105	37	data	datum	NOUN
gra-2157	105	38	and	and	CCONJ
gra-2157	105	39	clinical	clinical	ADJ
gra-2157	105	40	studies	study	NOUN
gra-2157	105	41	.	.	PUNCT
gra-2157	106	1	diab	diab	PROPN
gra-2157	106	2	metab	metab	PROPN
gra-2157	106	3	.	.	PUNCT
gra-2157	107	1	2000;26:254–64	2000;26:254–64	X
gra-2157	107	2	.	.	NOUN
gra-2157	107	3	8	8	NUM
gra-2157	107	4	.	.	PUNCT
gra-2157	108	1	ravid	ravid	PROPN
gra-2157	108	2	m	m	PROPN
gra-2157	108	3	,	,	PUNCT
gra-2157	108	4	neumann	neumann	PROPN
gra-2157	108	5	l	l	PROPN
gra-2157	108	6	lm	lm	PROPN
gra-2157	108	7	.	.	PUNCT
gra-2157	109	1	plasma	plasma	NOUN
gra-2157	109	2	lipids	lipid	NOUN
gra-2157	109	3	and	and	CCONJ
gra-2157	109	4	progression	progression	NOUN
gra-2157	109	5	of	of	ADP
gra-2157	109	6	nephropathy	nephropathy	NOUN
gra-2157	109	7	in	in	ADP
gra-2157	109	8	diabetes	diabetes	NOUN
gra-2157	109	9	mellitus	mellitus	PROPN
gra-2157	109	10	type	type	PROPN
gra-2157	109	11	ii	ii	PROPN
gra-2157	109	12	:	:	PUNCT
gra-2157	109	13	effect	effect	NOUN
gra-2157	109	14	of	of	ADP
gra-2157	109	15	ace	ace	ADJ
gra-2157	109	16	inhibitors	inhibitor	NOUN
gra-2157	109	17	.	.	PUNCT
gra-2157	110	1	kidney	kidney	NOUN
gra-2157	110	2	int	int	NOUN
gra-2157	110	3	.	.	PUNCT
gra-2157	111	1	1995;47:907–10	1995;47:907–10	X
gra-2157	111	2	.	.	NOUN
gra-2157	111	3	9	9	NUM
gra-2157	111	4	.	.	X
gra-2157	111	5	rosario	rosario	PROPN
gra-2157	111	6	rf	rf	PROPN
gra-2157	111	7	sp	sp	PROPN
gra-2157	111	8	.	.	PUNCT
gra-2157	111	9	lipids	lipids	ADJ
gra-2157	111	10	and	and	CCONJ
gra-2157	111	11	diabetic	diabetic	ADJ
gra-2157	111	12	nephropathy	nephropathy	NOUN
gra-2157	111	13	.	.	PUNCT
gra-2157	112	1	curr	curr	PROPN
gra-2157	112	2	diab	diab	PROPN
gra-2157	112	3	rep	rep	PROPN
gra-2157	112	4	.	.	PROPN
gra-2157	112	5	2006;6:455–62	2006;6:455–62	NUM
gra-2157	112	6	.	.	NOUN
gra-2157	112	7	10	10	NUM
gra-2157	112	8	.	.	PUNCT
gra-2157	113	1	munter	munter	PROPN
gra-2157	113	2	p	p	PROPN
gra-2157	113	3	,	,	PUNCT
gra-2157	113	4	coresh	coresh	PROPN
gra-2157	113	5	j	j	PROPN
gra-2157	113	6	,	,	PUNCT
gra-2157	113	7	smith	smith	PROPN
gra-2157	113	8	jc	jc	PROPN
gra-2157	113	9	,	,	PUNCT
gra-2157	113	10	eckfeldt	eckfeldt	PROPN
gra-2157	113	11	j	j	PROPN
gra-2157	113	12	km	km	PROPN
gra-2157	113	13	.	.	PUNCT
gra-2157	114	1	plasma	plasma	NOUN
gra-2157	114	2	lipids	lipid	NOUN
gra-2157	114	3	and	and	CCONJ
gra-2157	114	4	risk	risk	NOUN
gra-2157	114	5	of	of	ADP
gra-2157	114	6	developing	develop	VERB
gra-2157	114	7	renal	renal	ADJ
gra-2157	114	8	dysfunction	dysfunction	NOUN
gra-2157	114	9	:	:	PUNCT
gra-2157	114	10	the	the	DET
gra-2157	114	11	atherosclerosis	atherosclerosis	NOUN
gra-2157	114	12	risk	risk	NOUN
gra-2157	114	13	in	in	ADP
gra-2157	114	14	communities	community	NOUN
gra-2157	114	15	study	study	NOUN
gra-2157	114	16	.	.	PUNCT
gra-2157	115	1	kidney	kidney	NOUN
gra-2157	115	2	int	int	NOUN
gra-2157	115	3	.	.	PUNCT
gra-2157	116	1	2000;58:293–301	2000;58:293–301	NUM
gra-2157	116	2	.	.	PUNCT
gra-2157	117	1	11	11	NUM
gra-2157	117	2	.	.	PUNCT
gra-2157	118	1	wang	wang	PROPN
gra-2157	118	2	z	z	PROPN
gra-2157	118	3	,	,	PUNCT
gra-2157	118	4	jiang	jiang	PROPN
gra-2157	118	5	t	t	PROPN
gra-2157	118	6	,	,	PUNCT
gra-2157	118	7	li	li	PROPN
gra-2157	118	8	j	j	PROPN
gra-2157	118	9	,	,	PUNCT
gra-2157	118	10	proctor	proctor	PROPN
gra-2157	118	11	g	g	PROPN
gra-2157	118	12	,	,	PUNCT
gra-2157	118	13	mcmanaman	mcmanaman	NOUN
gra-2157	118	14	jl	jl	PROPN
gra-2157	118	15	,	,	PUNCT
gra-2157	118	16	lucia	lucia	PROPN
gra-2157	118	17	s	s	PART
gra-2157	118	18	et	et	PROPN
gra-2157	118	19	al	al	PROPN
gra-2157	118	20	.	.	PUNCT
gra-2157	118	21	regulation	regulation	NOUN
gra-2157	118	22	of	of	ADP
gra-2157	118	23	renal	renal	ADJ
gra-2157	118	24	lipid	lipid	NOUN
gra-2157	118	25	metabolism	metabolism	NOUN
gra-2157	118	26	,	,	PUNCT
gra-2157	118	27	lipid	lipid	NOUN
gra-2157	118	28	accumulation	accumulation	NOUN
gra-2157	118	29	and	and	CCONJ
gra-2157	118	30	glomerulosclerosis	glomerulosclerosis	NOUN
gra-2157	118	31	in	in	ADP
gra-2157	118	32	fvbdb	fvbdb	PROPN
gra-2157	118	33	/	/	SYM
gra-2157	118	34	db	db	VERB
gra-2157	118	35	mice	mouse	NOUN
gra-2157	118	36	with	with	ADP
gra-2157	118	37	type	type	NOUN
gra-2157	118	38	2	2	NUM
gra-2157	118	39	diabetes	diabetes	NOUN
gra-2157	118	40	.	.	PUNCT
gra-2157	119	1	diabetes	diabetes	NOUN
gra-2157	119	2	.	.	PUNCT
gra-2157	120	1	2005;54:2328–35	2005;54:2328–35	NUM
gra-2157	120	2	.	.	PUNCT
gra-2157	121	1	12	12	NUM
gra-2157	121	2	.	.	PUNCT
gra-2157	122	1	sun	sun	PROPN
gra-2157	122	2	l	l	PROPN
gra-2157	122	3	,	,	PUNCT
gra-2157	122	4	halaihel	halaihel	PROPN
gra-2157	122	5	n	n	CCONJ
gra-2157	122	6	,	,	PUNCT
gra-2157	122	7	zhang	zhang	PROPN
gra-2157	122	8	w	w	PROPN
gra-2157	122	9	,	,	PUNCT
gra-2157	122	10	rogers	rogers	PROPN
gra-2157	122	11	t	t	PROPN
gra-2157	122	12	lm	lm	PROPN
gra-2157	122	13	.	.	PUNCT
gra-2157	122	14	role	role	NOUN
gra-2157	122	15	of	of	ADP
gra-2157	122	16	sterol	sterol	NOUN
gra-2157	122	17	regulatory	regulatory	ADJ
gra-2157	122	18	elementbinding	elementbinding	NOUN
gra-2157	122	19	protein-1	protein-1	NUM
gra-2157	122	20	in	in	ADP
gra-2157	122	21	regulation	regulation	NOUN
gra-2157	122	22	of	of	ADP
gra-2157	122	23	renal	renal	ADJ
gra-2157	122	24	lipid	lipid	NOUN
gra-2157	122	25	metabolism	metabolism	NOUN
gra-2157	122	26	and	and	CCONJ
gra-2157	122	27	glomerulosclerosis	glomerulosclerosis	NOUN
gra-2157	122	28	in	in	ADP
gra-2157	122	29	diabetes	diabetes	NOUN
gra-2157	122	30	mellitus	mellitus	NOUN
gra-2157	122	31	.	.	PUNCT
gra-2157	123	1	j	j	PROPN
gra-2157	123	2	biol	biol	PROPN
gra-2157	123	3	chem	chem	NOUN
gra-2157	123	4	.	.	PUNCT
gra-2157	124	1	2002;277:18919–27	2002;277:18919–27	NOUN
gra-2157	124	2	.	.	PUNCT
gra-2157	125	1	13	13	NUM
gra-2157	125	2	.	.	PUNCT
gra-2157	126	1	balakumar	balakumar	PROPN
gra-2157	126	2	p	p	PROPN
gra-2157	126	3	,	,	PUNCT
gra-2157	126	4	arora	arora	PROPN
gra-2157	126	5	mk	mk	PROPN
gra-2157	126	6	,	,	PUNCT
gra-2157	126	7	singh	singh	PROPN
gra-2157	126	8	m.	m.	NOUN
gra-2157	126	9	emerging	emerge	VERB
gra-2157	126	10	role	role	NOUN
gra-2157	126	11	of	of	ADP
gra-2157	126	12	ppar	ppar	NOUN
gra-2157	126	13	ligands	ligand	NOUN
gra-2157	126	14	in	in	ADP
gra-2157	126	15	the	the	DET
gra-2157	126	16	management	management	NOUN
gra-2157	126	17	of	of	ADP
gra-2157	126	18	diabetic	diabetic	ADJ
gra-2157	126	19	nephropathy	nephropathy	NOUN
gra-2157	126	20	.	.	PUNCT
gra-2157	127	1	pharmacol	pharmacol	NOUN
gra-2157	127	2	res	re	NOUN
gra-2157	127	3	.	.	PUNCT
gra-2157	128	1	2009;60(3):170	2009;60(3):170	NUM
gra-2157	128	2	-	-	PUNCT
gra-2157	128	3	173	173	NUM
gra-2157	128	4	.	.	PUNCT
gra-2157	129	1	doi:10.1016	doi:10.1016	PROPN
gra-2157	129	2	/	/	SYM
gra-2157	129	3	j.phrs.2009.01.010	j.phrs.2009.01.010	PROPN
gra-2157	129	4	14	14	NUM
gra-2157	129	5	.	.	PUNCT
gra-2157	130	1	rippin	rippin	PROPN
gra-2157	130	2	j	j	PROPN
gra-2157	130	3	,	,	PUNCT
gra-2157	130	4	bain	bain	PROPN
gra-2157	130	5	sc	sc	PROPN
gra-2157	130	6	,	,	PUNCT
gra-2157	130	7	barnett	barnett	PROPN
gra-2157	130	8	ah	ah	INTJ
gra-2157	130	9	.	.	PUNCT
gra-2157	130	10	rationale	rationale	NOUN
gra-2157	130	11	and	and	CCONJ
gra-2157	130	12	design	design	NOUN
gra-2157	130	13	of	of	ADP
gra-2157	130	14	diabetics	diabetic	NOUN
gra-2157	130	15	exposed	expose	VERB
gra-2157	130	16	to	to	ADP
gra-2157	130	17	telmisartan	telmisartan	NOUN
gra-2157	130	18	and	and	CCONJ
gra-2157	130	19	enalapril	enalapril	PROPN
gra-2157	130	20	(	(	PUNCT
gra-2157	130	21	detail	detail	NOUN
gra-2157	130	22	)	)	PUNCT
gra-2157	130	23	study	study	NOUN
gra-2157	130	24	.	.	PUNCT
gra-2157	131	1	j	j	PROPN
gra-2157	131	2	diabetes	diabetes	NOUN
gra-2157	131	3	complications	complication	NOUN
gra-2157	131	4	.	.	PUNCT
gra-2157	132	1	2002;16(3):195	2002;16(3):195	NUM
gra-2157	132	2	-	-	SYM
gra-2157	132	3	200	200	NUM
gra-2157	132	4	.	.	PUNCT
gra-2157	133	1	doi:10.1016	doi:10.1016	PROPN
gra-2157	133	2	/	/	SYM
gra-2157	133	3	s1056	s1056	PROPN
gra-2157	133	4	-	-	PUNCT
gra-2157	133	5	8727(01)00165	8727(01)00165	NUM
gra-2157	133	6	-	-	SYM
gra-2157	133	7	9	9	NUM
gra-2157	133	8	15	15	NUM
gra-2157	133	9	.	.	PUNCT
gra-2157	134	1	bakris	bakris	PROPN
gra-2157	134	2	g	g	PROPN
gra-2157	134	3	,	,	PUNCT
gra-2157	134	4	burgess	burgess	PROPN
gra-2157	134	5	e	e	PROPN
gra-2157	134	6	,	,	PUNCT
gra-2157	134	7	weir	weir	PROPN
gra-2157	134	8	m	m	PROPN
gra-2157	134	9	,	,	PUNCT
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gra-2157	134	11	g	g	PROPN
gra-2157	134	12	,	,	PUNCT
gra-2157	134	13	koval	koval	PROPN
gra-2157	134	14	s.	s.	PROPN
gra-2157	134	15	telmisartan	telmisartan	PROPN
gra-2157	134	16	is	be	AUX
gra-2157	134	17	more	more	ADV
gra-2157	134	18	effective	effective	ADJ
gra-2157	134	19	than	than	ADP
gra-2157	134	20	losartan	losartan	ADJ
gra-2157	134	21	in	in	ADP
gra-2157	134	22	reducing	reduce	VERB
gra-2157	134	23	proteinuria	proteinuria	NOUN
gra-2157	134	24	in	in	ADP
gra-2157	134	25	patients	patient	NOUN
gra-2157	134	26	with	with	ADP
gra-2157	134	27	diabetic	diabetic	ADJ
gra-2157	134	28	nephropathy	nephropathy	NOUN
gra-2157	134	29	.	.	PUNCT
gra-2157	135	1	kidney	kidney	NOUN
gra-2157	135	2	int	int	NOUN
gra-2157	135	3	.	.	PUNCT
gra-2157	136	1	2008;74(3):364	2008;74(3):364	NUM
gra-2157	136	2	-	-	PUNCT
gra-2157	136	3	369	369	NUM
gra-2157	136	4	.	.	PUNCT
gra-2157	137	1	doi:10.1038	doi:10.1038	PROPN
gra-2157	137	2	/	/	SYM
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gra-2157	137	5	.	.	PUNCT
gra-2157	138	1	aranda	aranda	PROPN
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gra-2157	138	3	,	,	PUNCT
gra-2157	138	4	segura	segura	PROPN
gra-2157	138	5	j	j	PROPN
gra-2157	138	6	,	,	PUNCT
gra-2157	138	7	ruilope	ruilope	PROPN
gra-2157	138	8	lm	lm	PROPN
gra-2157	138	9	,	,	PUNCT
gra-2157	138	10	et	et	PROPN
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gra-2157	138	12	.	.	PUNCT
gra-2157	139	1	long	long	ADJ
gra-2157	139	2	-	-	PUNCT
gra-2157	139	3	term	term	NOUN
gra-2157	139	4	renoprotective	renoprotective	ADJ
gra-2157	139	5	effects	effect	NOUN
gra-2157	139	6	of	of	ADP
gra-2157	139	7	standard	standard	ADJ
gra-2157	139	8	versus	versus	ADP
gra-2157	139	9	high	high	ADJ
gra-2157	139	10	doses	dose	NOUN
gra-2157	139	11	of	of	ADP
gra-2157	139	12	telmisartan	telmisartan	PROPN
gra-2157	139	13	in	in	ADP
gra-2157	139	14	hypertensive	hypertensive	ADJ
gra-2157	139	15	nondiabetic	nondiabetic	ADJ
gra-2157	139	16	nephropathies	nephropathy	NOUN
gra-2157	139	17	.	.	PUNCT
gra-2157	140	1	am	be	AUX
gra-2157	140	2	j	j	PROPN
gra-2157	140	3	kidney	kidney	PROPN
gra-2157	140	4	dis	dis	PROPN
gra-2157	140	5	.	.	PUNCT
gra-2157	141	1	2005;46(6):1074	2005;46(6):1074	NUM
gra-2157	141	2	-	-	SYM
gra-2157	141	3	1079	1079	NUM
gra-2157	141	4	.	.	PUNCT
gra-2157	142	1	doi:10.105	doi:10.105	ADJ
gra-2157	142	2	3	3	X
gra-2157	142	3	/	/	SYM
gra-2157	142	4	j.a	j.a	PROPN
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gra-2157	142	6	17	17	NUM
gra-2157	142	7	.	.	PUNCT
gra-2157	142	8	schmieder	schmieder	PROPN
gra-2157	143	1	re	re	PROPN
gra-2157	143	2	,	,	PUNCT
gra-2157	143	3	delles	delle	VERB
gra-2157	143	4	c	c	PROPN
gra-2157	143	5	,	,	PUNCT
gra-2157	143	6	mimran	mimran	VERB
gra-2157	143	7	a	a	PRON
gra-2157	143	8	,	,	PUNCT
gra-2157	143	9	fauvel	fauvel	NOUN
gra-2157	143	10	jp	jp	NOUN
gra-2157	143	11	rl	rl	X
gra-2157	143	12	.	.	PROPN
gra-2157	143	13	impact	impact	NOUN
gra-2157	143	14	of	of	ADP
gra-2157	143	15	telmisartan	telmisartan	PROPN
gra-2157	143	16	versus	versus	ADP
gra-2157	143	17	ramipril	ramipril	PROPN
gra-2157	143	18	on	on	ADP
gra-2157	143	19	renal	renal	ADJ
gra-2157	143	20	endothelial	endothelial	ADJ
gra-2157	143	21	function	function	NOUN
gra-2157	143	22	in	in	ADP
gra-2157	143	23	patients	patient	NOUN
gra-2157	143	24	with	with	ADP
gra-2157	143	25	hypertension	hypertension	NOUN
gra-2157	143	26	and	and	CCONJ
gra-2157	143	27	type	type	NOUN
gra-2157	143	28	2	2	NUM
gra-2157	143	29	diabetes	diabetes	NOUN
gra-2157	143	30	.	.	PUNCT
gra-2157	144	1	diabetes	diabetes	NOUN
gra-2157	144	2	care	care	VERB
gra-2157	144	3	.	.	PUNCT
gra-2157	145	1	2007;30:1351	2007;30:1351	PROPN
gra-2157	145	2	-	-	SYM
gra-2157	145	3	1356	1356	NUM
gra-2157	145	4	.	.	PUNCT
gra-2157	146	1	volume-9	volume-9	NUM
gra-2157	146	2	,	,	PUNCT
gra-2157	146	3	issue-3	issue-3	NUM
gra-2157	146	4	,	,	PUNCT
gra-2157	146	5	march-2020	march-2020	ADJ
gra-2157	146	6	•	•	NOUN
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gra-2157	146	10	.	.	PROPN
gra-2157	147	1	2277	2277	NUM
gra-2157	147	2	8160	8160	NUM
gra-2157	147	3	•	•	NOUN
gra-2157	147	4	doi	doi	NOUN
gra-2157	147	5	:	:	PUNCT
gra-2157	147	6	10.36106	10.36106	NUM
gra-2157	147	7	/	/	SYM
gra-2157	147	8	gjra	gjra	NOUN
gra-2157	147	9	40	40	NUM
gra-2157	147	10	x	x	NOUN
gra-2157	147	11	gjra	gjra	ADJ
gra-2157	147	12	global	global	ADJ
gra-2157	147	13	journal	journal	PROPN
gra-2157	147	14	for	for	ADP
gra-2157	147	15	research	research	NOUN
gra-2157	147	16	analysis	analysis	NOUN