id	sid	tid	token	lemma	pos
gra-48	1	1	introducti̇on	introducti̇on	PROPN
gra-48	1	2	:	:	PUNCT
gra-48	1	3	colorectal	colorectal	ADJ
gra-48	1	4	cancer	cancer	NOUN
gra-48	1	5	(	(	PUNCT
gra-48	1	6	crc	crc	NOUN
gra-48	1	7	)	)	PUNCT
gra-48	1	8	is	be	AUX
gra-48	1	9	the	the	DET
gra-48	1	10	third	third	ADJ
gra-48	1	11	most	most	ADV
gra-48	1	12	common	common	ADJ
gra-48	1	13	cancer	cancer	NOUN
gra-48	1	14	and	and	CCONJ
gra-48	1	15	nearly	nearly	ADV
gra-48	1	16	one	one	NUM
gra-48	1	17	million	million	NUM
gra-48	1	18	new	new	ADJ
gra-48	1	19	cases	case	NOUN
gra-48	1	20	has	have	AUX
gra-48	1	21	been	be	AUX
gra-48	1	22	diagnosed	diagnose	VERB
gra-48	1	23	annually(1	annually(1	PROPN
gra-48	1	24	)	)	PUNCT
gra-48	1	25	colorectal	colorectal	ADJ
gra-48	1	26	cancer	cancer	NOUN
gra-48	1	27	pogression	pogression	NOUN
gra-48	1	28	is	be	AUX
gra-48	1	29	a	a	DET
gra-48	1	30	multistep	multistep	ADJ
gra-48	1	31	process	process	NOUN
gra-48	1	32	,	,	PUNCT
gra-48	1	33	in	in	ADP
gra-48	1	34	which	which	PRON
gra-48	1	35	many	many	ADJ
gra-48	1	36	genes	gene	NOUN
gra-48	1	37	and	and	CCONJ
gra-48	1	38	proteins	protein	NOUN
gra-48	1	39	are	be	AUX
gra-48	1	40	involved	involve	VERB
gra-48	1	41	.	.	PUNCT
gra-48	2	1	the	the	DET
gra-48	2	2	function	function	NOUN
gra-48	2	3	of	of	ADP
gra-48	2	4	extracellular	extracellular	ADJ
gra-48	2	5	matrix	matrix	NOUN
gra-48	2	6	in	in	ADP
gra-48	2	7	many	many	ADJ
gra-48	2	8	kinds	kind	NOUN
gra-48	2	9	of	of	ADP
gra-48	2	10	cancers	cancer	NOUN
gra-48	2	11	have	have	AUX
gra-48	2	12	been	be	AUX
gra-48	2	13	revealed	reveal	VERB
gra-48	2	14	and	and	CCONJ
gra-48	2	15	their	their	PRON
gra-48	2	16	role	role	NOUN
gra-48	2	17	of	of	ADP
gra-48	2	18	the	the	DET
gra-48	2	19	clinical	clinical	ADJ
gra-48	2	20	signicance	signicance	NOUN
gra-48	2	21	in	in	ADP
gra-48	2	22	colorectal	colorectal	ADJ
gra-48	2	23	cancer	cancer	NOUN
gra-48	2	24	is	be	AUX
gra-48	2	25	under	under	ADP
gra-48	2	26	investigation	investigation	NOUN
gra-48	2	27	.	.	PUNCT
gra-48	3	1	the	the	DET
gra-48	3	2	matrix	matrix	NOUN
gra-48	3	3	metalloproteinases	metalloproteinase	NOUN
gra-48	3	4	(	(	PUNCT
gra-48	3	5	mmps	mmp	NOUN
gra-48	3	6	)	)	PUNCT
gra-48	3	7	are	be	AUX
gra-48	3	8	a	a	DET
gra-48	3	9	family	family	NOUN
gra-48	3	10	of	of	ADP
gra-48	3	11	zincdependent	zincdependent	NOUN
gra-48	3	12	endopeptidases	endopeptidase	NOUN
gra-48	3	13	that	that	PRON
gra-48	3	14	are	be	AUX
gra-48	3	15	involved	involve	VERB
gra-48	3	16	in	in	ADP
gra-48	3	17	degrading	degrade	VERB
gra-48	3	18	extracellular	extracellular	ADJ
gra-48	3	19	matrix	matrix	NOUN
gra-48	3	20	and	and	CCONJ
gra-48	3	21	facilitating	facilitate	VERB
gra-48	3	22	tumor	tumor	NOUN
gra-48	3	23	invasion(2,3	invasion(2,3	NOUN
gra-48	3	24	)	)	PUNCT
gra-48	3	25	mmp9	mmp9	PROPN
gra-48	3	26	and	and	CCONJ
gra-48	3	27	mmp-2	mmp-2	NOUN
gra-48	3	28	are	be	AUX
gra-48	3	29	gelatinases	gelatinase	NOUN
gra-48	3	30	of	of	ADP
gra-48	3	31	mmp	mmp	PROPN
gra-48	3	32	family	family	PROPN
gra-48	3	33	and	and	CCONJ
gra-48	3	34	degrade	degrade	VERB
gra-48	3	35	substrates	substrate	NOUN
gra-48	3	36	of	of	ADP
gra-48	3	37	type	type	NOUN
gra-48	3	38	iv	iv	NUM
gra-48	3	39	collagen	collagen	NOUN
gra-48	3	40	and	and	CCONJ
gra-48	3	41	gelatin	gelatin	NOUN
gra-48	3	42	.	.	PUNCT
gra-48	4	1	previous	previous	ADJ
gra-48	4	2	studies	study	NOUN
gra-48	4	3	have	have	AUX
gra-48	4	4	demonstrated	demonstrate	VERB
gra-48	4	5	that	that	SCONJ
gra-48	4	6	mmp-2	mmp-2	PRON
gra-48	4	7	is	be	AUX
gra-48	4	8	associated	associate	VERB
gra-48	4	9	with	with	ADP
gra-48	4	10	invasion	invasion	NOUN
gra-48	4	11	and	and	CCONJ
gra-48	4	12	metastasis	metastasis	NOUN
gra-48	4	13	in	in	ADP
gra-48	4	14	colorectal	colorectal	ADJ
gra-48	4	15	carcinoma	carcinoma	NOUN
gra-48	4	16	(	(	PUNCT
gra-48	4	17	4,5,6	4,5,6	NUM
gra-48	4	18	)	)	PUNCT
gra-48	4	19	e	e	NOUN
gra-48	4	20	-	-	NOUN
gra-48	4	21	cadherin	cadherin	NOUN
gra-48	4	22	is	be	AUX
gra-48	4	23	a	a	DET
gra-48	4	24	key	key	ADJ
gra-48	4	25	mediator	mediator	NOUN
gra-48	4	26	of	of	ADP
gra-48	4	27	cell	cell	NOUN
gra-48	4	28	–	–	PUNCT
gra-48	4	29	cell	cell	NOUN
gra-48	4	30	adhesions	adhesion	NOUN
gra-48	4	31	in	in	ADP
gra-48	4	32	epithelial	epithelial	ADJ
gra-48	4	33	tissues	tissue	NOUN
gra-48	4	34	,	,	PUNCT
gra-48	4	35	and	and	CCONJ
gra-48	4	36	loss	loss	NOUN
gra-48	4	37	of	of	ADP
gra-48	4	38	e	e	NOUN
gra-48	4	39	-	-	NOUN
gra-48	4	40	cadherin	cadherin	NOUN
gra-48	4	41	can	can	AUX
gra-48	4	42	promote	promote	VERB
gra-48	4	43	invasive	invasive	ADJ
gra-48	4	44	and	and	CCONJ
gra-48	4	45	metastatic	metastatic	ADJ
gra-48	4	46	behaviour	behaviour	NOUN
gra-48	4	47	in	in	ADP
gra-48	4	48	many	many	ADJ
gra-48	4	49	epithelial	epithelial	ADJ
gra-48	4	50	tumours	tumour	NOUN
gra-48	4	51	,	,	PUNCT
gra-48	4	52	also	also	ADV
gra-48	4	53	(	(	PUNCT
gra-48	4	54	7	7	NUM
gra-48	4	55	)	)	PUNCT
gra-48	4	56	.	.	PUNCT
gra-48	5	1	the	the	DET
gra-48	5	2	cytoplasmic	cytoplasmic	ADJ
gra-48	5	3	domain	domain	NOUN
gra-48	5	4	of	of	ADP
gra-48	5	5	e	e	NOUN
gra-48	5	6	-	-	NOUN
gra-48	5	7	cadherin	cadherin	NOUN
gra-48	5	8	interacts	interact	VERB
gra-48	5	9	with	with	ADP
gra-48	5	10	catenin	catenin	ADJ
gra-48	5	11	molecules	molecule	NOUN
gra-48	5	12	,	,	PUNCT
gra-48	5	13	including	include	VERB
gra-48	5	14	β	β	NOUN
gra-48	5	15	-	-	NOUN
gra-48	5	16	catenin	catenin	NOUN
gra-48	5	17	.	.	PUNCT
gra-48	6	1	β	β	X
gra-48	6	2	-	-	NOUN
gra-48	6	3	catenin	catenin	NOUN
gra-48	6	4	which	which	PRON
gra-48	6	5	is	be	AUX
gra-48	6	6	major	major	ADJ
gra-48	6	7	mediator	mediator	NOUN
gra-48	6	8	cadherin	cadherin	NOUN
gra-48	6	9	-	-	PUNCT
gra-48	6	10	associated	associate	VERB
gra-48	6	11	protein	protein	NOUN
gra-48	6	12	play	play	VERB
gra-48	6	13	important	important	ADJ
gra-48	6	14	role	role	NOUN
gra-48	6	15	in	in	ADP
gra-48	6	16	wnt	wnt	NOUN
gra-48	6	17	signalling	signal	VERB
gra-48	6	18	pathway	pathway	NOUN
gra-48	6	19	.	.	PUNCT
gra-48	7	1	mutations	mutation	NOUN
gra-48	7	2	in	in	ADP
gra-48	7	3	adenomatous	adenomatous	ADJ
gra-48	7	4	polyposis	polyposis	NOUN
gra-48	7	5	coli	coli	NOUN
gra-48	7	6	(	(	PUNCT
gra-48	7	7	apc	apc	PROPN
gra-48	7	8	)	)	PUNCT
gra-48	7	9	which	which	PRON
gra-48	7	10	is	be	AUX
gra-48	7	11	a	a	DET
gra-48	7	12	tumour	tumour	NOUN
gra-48	7	13	suppresser	suppresser	NOUN
gra-48	7	14	gen	gen	PROPN
gra-48	7	15	leads	lead	VERB
gra-48	7	16	to	to	ADP
gra-48	7	17	enhances	enhance	VERB
gra-48	7	18	β	β	NOUN
gra-48	7	19	-	-	ADJ
gra-48	7	20	catenin	catenin	ADJ
gra-48	7	21	gene	gene	NOUN
gra-48	7	22	expression	expression	NOUN
gra-48	7	23	.	.	PUNCT
gra-48	8	1	(	(	PUNCT
gra-48	8	2	8)	8)	NUM
gra-48	8	3	.	.	PUNCT
gra-48	9	1	when	when	SCONJ
gra-48	9	2	β	β	X
gra-48	9	3	-	-	ADJ
gra-48	9	4	catenin	catenin	NOUN
gra-48	9	5	accumulates	accumulate	VERB
gra-48	9	6	,	,	PUNCT
gra-48	9	7	it	it	PRON
gra-48	9	8	translocates	translocate	VERB
gra-48	9	9	to	to	ADP
gra-48	9	10	the	the	DET
gra-48	9	11	nucleus	nucleus	NOUN
gra-48	9	12	,	,	PUNCT
gra-48	9	13	and	and	CCONJ
gra-48	9	14	associates	associate	NOUN
gra-48	9	15	with	with	ADP
gra-48	9	16	tcf	tcf	PROPN
gra-48	9	17	/	/	SYM
gra-48	9	18	lef	lef	PROPN
gra-48	9	19	,	,	PUNCT
gra-48	9	20	leading	lead	VERB
gra-48	9	21	to	to	ADP
gra-48	9	22	its	its	PRON
gra-48	9	23	binding	binding	NOUN
gra-48	9	24	to	to	ADP
gra-48	9	25	dna	dna	NOUN
gra-48	9	26	and	and	CCONJ
gra-48	9	27	subsequent	subsequent	ADJ
gra-48	9	28	transcription	transcription	NOUN
gra-48	9	29	of	of	ADP
gra-48	9	30	genes	gene	NOUN
gra-48	9	31	associated	associate	VERB
gra-48	9	32	with	with	ADP
gra-48	9	33	crc	crc	PROPN
gra-48	9	34	development	development	PROPN
gra-48	9	35	.	.	PUNCT
gra-48	10	1	wnt	wnt	PROPN
gra-48	10	2	/	/	SYM
gra-48	10	3	β‐catenin	β‐catenin	PUNCT
gra-48	10	4	signaling	signal	VERB
gra-48	10	5	pathway	pathway	NOUN
gra-48	10	6	is	be	AUX
gra-48	10	7	aberrantly	aberrantly	ADV
gra-48	10	8	activated	activate	VERB
gra-48	10	9	and	and	CCONJ
gra-48	10	10	responsible	responsible	ADJ
gra-48	10	11	for	for	ADP
gra-48	10	12	upregulating	upregulating	ADJ
gra-48	10	13	mmps	mmps	NOUN
gra-48	10	14	expression	expression	NOUN
gra-48	10	15	(	(	PUNCT
gra-48	10	16	9,10	9,10	NUM
gra-48	10	17	)	)	PUNCT
gra-48	10	18	.	.	PUNCT
gra-48	11	1	disturbance	disturbance	NOUN
gra-48	11	2	of	of	ADP
gra-48	11	3	the	the	DET
gra-48	11	4	e	e	NOUN
gra-48	11	5	-	-	NOUN
gra-48	11	6	cadherin	cadherin	NOUN
gra-48	11	7	/	/	SYM
gra-48	11	8	catenin	catenin	NOUN
gra-48	11	9	complex	complex	NOUN
gra-48	11	10	during	during	ADP
gra-48	11	11	tumor	tumor	NOUN
gra-48	11	12	progression	progression	NOUN
gra-48	11	13	is	be	AUX
gra-48	11	14	correlated	correlate	VERB
gra-48	11	15	with	with	ADP
gra-48	11	16	the	the	DET
gra-48	11	17	onset	onset	NOUN
gra-48	11	18	of	of	ADP
gra-48	11	19	an	an	DET
gra-48	11	20	invasive	invasive	ADJ
gra-48	11	21	phenotype	phenotype	NOUN
gra-48	11	22	(	(	PUNCT
gra-48	11	23	11	11	NUM
gra-48	11	24	)	)	PUNCT
gra-48	11	25	.	.	PUNCT
gra-48	12	1	in	in	ADP
gra-48	12	2	addition	addition	NOUN
gra-48	12	3	,	,	PUNCT
gra-48	12	4	studies	study	NOUN
gra-48	12	5	suggested	suggest	VERB
gra-48	12	6	that	that	SCONJ
gra-48	12	7	the	the	DET
gra-48	12	8	matrix	matrix	NOUN
gra-48	12	9	metalloproteinase	metalloproteinase	NOUN
gra-48	12	10	leads	lead	VERB
gra-48	12	11	directly	directly	ADV
gra-48	12	12	or	or	CCONJ
gra-48	12	13	indirectly	indirectly	ADV
gra-48	12	14	to	to	ADP
gra-48	12	15	shedding	shed	VERB
gra-48	12	16	of	of	ADP
gra-48	12	17	the	the	DET
gra-48	12	18	e	e	NOUN
gra-48	12	19	-	-	NOUN
gra-48	12	20	cadherin	cadherin	NOUN
gra-48	12	21	(	(	PUNCT
gra-48	12	22	12	12	NUM
gra-48	12	23	)	)	PUNCT
gra-48	12	24	.	.	PUNCT
gra-48	13	1	in	in	ADP
gra-48	13	2	our	our	PRON
gra-48	13	3	study	study	NOUN
gra-48	13	4	,	,	PUNCT
gra-48	13	5	we	we	PRON
gra-48	13	6	aim	aim	VERB
gra-48	13	7	to	to	PART
gra-48	13	8	investigate	investigate	VERB
gra-48	13	9	the	the	DET
gra-48	13	10	expression	expression	NOUN
gra-48	13	11	of	of	ADP
gra-48	13	12	ecadherin	ecadherin	NOUN
gra-48	13	13	and	and	CCONJ
gra-48	13	14	mmp-2	mmp-2	NOUN
gra-48	13	15	in	in	ADP
gra-48	13	16	colorectal	colorectal	ADJ
gra-48	13	17	cancer	cancer	NOUN
gra-48	13	18	and	and	CCONJ
gra-48	13	19	their	their	PRON
gra-48	13	20	associations	association	NOUN
gra-48	13	21	with	with	ADP
gra-48	13	22	clinical	clinical	ADJ
gra-48	13	23	pathological	pathological	ADJ
gra-48	13	24	features	feature	NOUN
gra-48	13	25	.	.	PUNCT
gra-48	14	1	materi̇al	materi̇al	NOUN
gra-48	14	2	and	and	CCONJ
gra-48	14	3	methods	method	NOUN
gra-48	14	4	:	:	PUNCT
gra-48	14	5	tissue	tissue	NOUN
gra-48	14	6	samples	sample	NOUN
gra-48	14	7	and	and	CCONJ
gra-48	14	8	patients	patient	NOUN
gra-48	14	9	the	the	DET
gra-48	14	10	study	study	NOUN
gra-48	14	11	was	be	AUX
gra-48	14	12	designed	design	VERB
gra-48	14	13	as	as	ADP
gra-48	14	14	retrospectively	retrospectively	ADV
gra-48	14	15	and	and	CCONJ
gra-48	14	16	due	due	ADP
gra-48	14	17	to	to	ADP
gra-48	14	18	retrospective	retrospective	ADJ
gra-48	14	19	nature	nature	NOUN
gra-48	14	20	of	of	ADP
gra-48	14	21	the	the	DET
gra-48	14	22	study	study	NOUN
gra-48	14	23	informed	inform	VERB
gra-48	14	24	consent	consent	NOUN
gra-48	14	25	was	be	AUX
gra-48	14	26	not	not	PART
gra-48	14	27	required	require	VERB
gra-48	14	28	.	.	PUNCT
gra-48	15	1	this	this	DET
gra-48	15	2	research	research	NOUN
gra-48	15	3	did	do	AUX
gra-48	15	4	not	not	PART
gra-48	15	5	receive	receive	VERB
gra-48	15	6	any	any	DET
gra-48	15	7	specic	specic	NOUN
gra-48	15	8	grant	grant	NOUN
gra-48	15	9	from	from	ADP
gra-48	15	10	funding	fund	VERB
gra-48	15	11	agencies	agency	NOUN
gra-48	15	12	in	in	ADP
gra-48	15	13	the	the	DET
gra-48	15	14	public	public	ADJ
gra-48	15	15	,	,	PUNCT
gra-48	15	16	commercial	commercial	ADJ
gra-48	15	17	,	,	PUNCT
gra-48	15	18	or	or	CCONJ
gra-48	15	19	not	not	PART
gra-48	15	20	-	-	PUNCT
gra-48	15	21	forprot	forprot	ADJ
gra-48	15	22	sectors	sector	NOUN
gra-48	15	23	.	.	PUNCT
gra-48	16	1	our	our	PRON
gra-48	16	2	study	study	NOUN
gra-48	16	3	consisted	consist	VERB
gra-48	16	4	of	of	ADP
gra-48	16	5	48	48	NUM
gra-48	16	6	patients	patient	NOUN
gra-48	16	7	with	with	ADP
gra-48	16	8	colorectal	colorectal	ADJ
gra-48	16	9	cancer	cancer	NOUN
gra-48	16	10	who	who	PRON
gra-48	16	11	had	have	AUX
gra-48	16	12	undergone	undergo	VERB
gra-48	16	13	surgical	surgical	ADJ
gra-48	16	14	resections	resection	NOUN
gra-48	16	15	at	at	ADP
gra-48	16	16	baskent	baskent	NOUN
gra-48	16	17	university	university	NOUN
gra-48	16	18	hospital	hospital	NOUN
gra-48	16	19	between	between	ADP
gra-48	16	20	2014	2014	NUM
gra-48	16	21	and	and	CCONJ
gra-48	16	22	2018	2018	NUM
gra-48	16	23	.	.	PUNCT
gra-48	17	1	the	the	DET
gra-48	17	2	study	study	NOUN
gra-48	17	3	group	group	NOUN
gra-48	17	4	consisted	consist	VERB
gra-48	17	5	of	of	ADP
gra-48	17	6	24	24	NUM
gra-48	17	7	classic	classic	ADJ
gra-48	17	8	adenocarcinomas	adenocarcinoma	NOUN
gra-48	17	9	and	and	CCONJ
gra-48	17	10	24	24	NUM
gra-48	17	11	mucinous	mucinous	ADJ
gra-48	17	12	adenocarcinomas	adenocarcinoma	NOUN
gra-48	17	13	.	.	PUNCT
gra-48	18	1	tumor	tumor	NOUN
gra-48	18	2	staging	staging	NOUN
gra-48	18	3	and	and	CCONJ
gra-48	18	4	histological	histological	ADJ
gra-48	18	5	classications	classication	NOUN
gra-48	18	6	were	be	AUX
gra-48	18	7	assessed	assess	VERB
gra-48	18	8	according	accord	VERB
gra-48	18	9	to	to	ADP
gra-48	18	10	world	world	PROPN
gra-48	18	11	health	health	NOUN
gra-48	18	12	organization	organization	NOUN
gra-48	18	13	classication	classication	NOUN
gra-48	18	14	(	(	PUNCT
gra-48	18	15	13	13	NUM
gra-48	18	16	)	)	PUNCT
gra-48	18	17	.	.	PUNCT
gra-48	19	1	of	of	ADP
gra-48	19	2	the	the	DET
gra-48	19	3	patients	patient	NOUN
gra-48	19	4	,	,	PUNCT
gra-48	19	5	35	35	NUM
gra-48	19	6	were	be	AUX
gra-48	19	7	men	man	NOUN
gra-48	19	8	(	(	PUNCT
gra-48	19	9	62,867	62,867	NUM
gra-48	19	10	%	%	NOUN
gra-48	19	11	)	)	PUNCT
gra-48	19	12	and	and	CCONJ
gra-48	19	13	13	13	NUM
gra-48	19	14	were	be	AUX
gra-48	19	15	women	woman	NOUN
gra-48	19	16	(	(	PUNCT
gra-48	19	17	37,14	37,14	NUM
gra-48	19	18	%	%	NOUN
gra-48	19	19	)	)	PUNCT
gra-48	19	20	.	.	PUNCT
gra-48	20	1	,	,	PUNCT
gra-48	20	2	the	the	DET
gra-48	20	3	patients	patient	NOUN
gra-48	20	4	ranged	range	VERB
gra-48	20	5	in	in	ADP
gra-48	20	6	age	age	NOUN
gra-48	20	7	from	from	ADP
gra-48	20	8	30–84	30–84	NUM
gra-48	20	9	years	year	NOUN
gra-48	20	10	(	(	PUNCT
gra-48	20	11	mean	mean	VERB
gra-48	20	12	,	,	PUNCT
gra-48	20	13	57,52	57,52	NUM
gra-48	20	14	+	+	NUM
gra-48	20	15	14,98	14,98	NOUN
gra-48	20	16	years).the	years).the	PRON
gra-48	20	17	investigated	investigate	VERB
gra-48	20	18	tumors	tumor	NOUN
gra-48	20	19	were	be	AUX
gra-48	20	20	classied	classied	PROPN
gra-48	20	21	as	as	SCONJ
gra-48	20	22	pt1	pt1	PROPN
gra-48	20	23	tumor	tumor	NOUN
gra-48	20	24	was	be	AUX
gra-48	20	25	observed	observe	VERB
gra-48	20	26	in	in	ADP
gra-48	20	27	(	(	PUNCT
gra-48	20	28	n:3	n:3	NOUN
gra-48	20	29	)	)	PUNCT
gra-48	20	30	6,25	6,25	NUM
gra-48	20	31	%	%	NOUN
gra-48	20	32	of	of	ADP
gra-48	20	33	patients	patient	NOUN
gra-48	20	34	,	,	PUNCT
gra-48	20	35	pt2	pt2	PROPN
gra-48	20	36	tumor	tumor	NOUN
gra-48	20	37	in	in	ADP
gra-48	20	38	(	(	PUNCT
gra-48	20	39	n:20	n:20	ADJ
gra-48	20	40	)	)	PUNCT
gra-48	20	41	41,66	41,66	NUM
gra-48	20	42	%	%	NOUN
gra-48	20	43	of	of	ADP
gra-48	20	44	patients	patient	NOUN
gra-48	20	45	,	,	PUNCT
gra-48	20	46	pt3	pt3	VERB
gra-48	20	47	tumor	tumor	NOUN
gra-48	20	48	in	in	ADP
gra-48	20	49	(	(	PUNCT
gra-48	20	50	n:18	n:18	PROPN
gra-48	20	51	)	)	PUNCT
gra-48	20	52	37,59	37,59	NUM
gra-48	20	53	%	%	NOUN
gra-48	20	54	of	of	ADP
gra-48	20	55	patients	patient	NOUN
gra-48	20	56	and	and	CCONJ
gra-48	20	57	pt4	pt4	PROPN
gra-48	20	58	tumor	tumor	NOUN
gra-48	20	59	in	in	ADP
gra-48	20	60	(	(	PUNCT
gra-48	20	61	n:7)14,585	n:7)14,585	NOUN
gra-48	20	62	%	%	NOUN
gra-48	20	63	of	of	ADP
gra-48	20	64	patients	patient	NOUN
gra-48	20	65	.	.	PUNCT
gra-48	21	1	among	among	ADP
gra-48	21	2	them	they	PRON
gra-48	21	3	(	(	PUNCT
gra-48	21	4	n:4	n:4	NOUN
gra-48	21	5	)	)	PUNCT
gra-48	21	6	8,33	8,33	NUM
gra-48	21	7	%	%	NOUN
gra-48	21	8	were	be	AUX
gra-48	21	9	located	locate	VERB
gra-48	21	10	at	at	ADP
gra-48	21	11	right	right	ADJ
gra-48	21	12	colon	colon	NOUN
gra-48	21	13	and	and	CCONJ
gra-48	21	14	(	(	PUNCT
gra-48	21	15	n:44	n:44	ADJ
gra-48	21	16	)	)	PUNCT
gra-48	21	17	91,67	91,67	NOUN
gra-48	21	18	%	%	NOUN
gra-48	21	19	were	be	AUX
gra-48	21	20	located	locate	VERB
gra-48	21	21	at	at	ADP
gra-48	21	22	left	leave	VERB
gra-48	21	23	colon	colon	NOUN
gra-48	21	24	.	.	PUNCT
gra-48	22	1	the	the	DET
gra-48	22	2	control	control	PROPN
gra-48	22	3	group	group	NOUN
gra-48	22	4	consisted	consist	VERB
gra-48	22	5	of	of	ADP
gra-48	22	6	20	20	NUM
gra-48	22	7	normal	normal	ADJ
gra-48	22	8	colon	colon	NOUN
gra-48	22	9	mucosa	mucosa	NOUN
gra-48	22	10	.	.	PUNCT
gra-48	23	1	the	the	DET
gra-48	23	2	clicopathologic	clicopathologic	NOUN
gra-48	23	3	features	feature	NOUN
gra-48	23	4	of	of	ADP
gra-48	23	5	cases	case	NOUN
gra-48	23	6	has	have	AUX
gra-48	23	7	been	be	AUX
gra-48	23	8	listed	list	VERB
gra-48	23	9	in	in	ADP
gra-48	23	10	table	table	NOUN
gra-48	23	11	i	i	PRON
gra-48	23	12	.	.	PUNCT
gra-48	24	1	immunohistochemical	immunohistochemical	ADJ
gra-48	24	2	staining	staining	NOUN
gra-48	24	3	:	:	PUNCT
gra-48	24	4	immunohistochemistry	immunohistochemistry	NOUN
gra-48	24	5	was	be	AUX
gra-48	24	6	performed	perform	VERB
gra-48	24	7	using	use	VERB
gra-48	24	8	antibodies	antibody	NOUN
gra-48	24	9	to	to	ADP
gra-48	24	10	mmp-2	mmp-2	NUM
gra-48	24	11	,	,	PUNCT
gra-48	24	12	(	(	PUNCT
gra-48	24	13	novo	novo	PROPN
gra-48	24	14	castra	castra	PROPN
gra-48	24	15	,	,	PUNCT
gra-48	24	16	clone	clone	NOUN
gra-48	24	17	17c2	17c2	NUM
gra-48	24	18	,	,	PUNCT
gra-48	24	19	1/100	1/100	NUM
gra-48	24	20	dilution	dilution	NOUN
gra-48	24	21	)	)	PUNCT
gra-48	24	22	,	,	PUNCT
gra-48	24	23	e	e	X
gra-48	24	24	cadherin	cadherin	NOUN
gra-48	24	25	(	(	PUNCT
gra-48	24	26	biogenex	biogenex	PROPN
gra-48	24	27	,	,	PUNCT
gra-48	24	28	clone	clone	NOUN
gra-48	24	29	ep	ep	PROPN
gra-48	24	30	,	,	PUNCT
gra-48	24	31	1/300	1/300	NUM
gra-48	24	32	dilution	dilution	NOUN
gra-48	24	33	)	)	PUNCT
gra-48	24	34	immuno	immuno	NOUN
gra-48	24	35	staining	stain	VERB
gra-48	24	36	were	be	AUX
gra-48	24	37	performed	perform	VERB
gra-48	24	38	by	by	ADP
gra-48	24	39	using	use	VERB
gra-48	24	40	manuel	manuel	NOUN
gra-48	24	41	method	method	NOUN
gra-48	24	42	.	.	PUNCT
gra-48	25	1	in	in	ADP
gra-48	25	2	manuel	manuel	PROPN
gra-48	25	3	method	method	PROPN
gra-48	25	4	,	,	PUNCT
gra-48	25	5	tissue	tissue	NOUN
gra-48	25	6	sections	section	NOUN
gra-48	25	7	(	(	PUNCT
gra-48	25	8	4	4	NUM
gra-48	25	9	µm	µm	ADP
gra-48	25	10	thick	thick	ADJ
gra-48	25	11	)	)	PUNCT
gra-48	25	12	were	be	AUX
gra-48	25	13	cut	cut	VERB
gra-48	25	14	,	,	PUNCT
gra-48	25	15	deparafnized	deparafnize	VERB
gra-48	25	16	in	in	ADP
gra-48	25	17	xylene	xylene	NOUN
gra-48	25	18	,	,	PUNCT
gra-48	25	19	dehydrated	dehydrate	VERB
gra-48	25	20	with	with	ADP
gra-48	25	21	graded	grade	VERB
gra-48	25	22	ethanol	ethanol	NOUN
gra-48	25	23	and	and	CCONJ
gra-48	25	24	then	then	ADV
gra-48	25	25	the	the	DET
gra-48	25	26	sections	section	NOUN
gra-48	25	27	were	be	AUX
gra-48	25	28	placed	place	VERB
gra-48	25	29	in	in	ADP
gra-48	25	30	10	10	NUM
gra-48	25	31	mm	mm	NOUN
gra-48	25	32	citrate	citrate	NOUN
gra-48	25	33	buffer	buffer	NOUN
gra-48	25	34	solution	solution	NOUN
gra-48	25	35	(	(	PUNCT
gra-48	25	36	ph	ph	NOUN
gra-48	25	37	7,3	7,3	NUM
gra-48	25	38	)	)	PUNCT
gra-48	25	39	and	and	CCONJ
gra-48	25	40	processed	process	VERB
gra-48	25	41	in	in	ADP
gra-48	25	42	an	an	DET
gra-48	25	43	autoclave	autoclave	NOUN
gra-48	25	44	for	for	ADP
gra-48	25	45	1,5	1,5	NUM
gra-48	25	46	minutes	minute	NOUN
gra-48	25	47	at	at	ADP
gra-48	25	48	120	120	NUM
gra-48	25	49	°	°	ADP
gra-48	25	50	c	c	NOUN
gra-48	25	51	for	for	ADP
gra-48	25	52	antigen	antigen	ADJ
gra-48	25	53	retrieval	retrieval	NOUN
gra-48	25	54	.	.	PUNCT
gra-48	26	1	after	after	ADP
gra-48	26	2	washing	wash	VERB
gra-48	26	3	in	in	ADP
gra-48	26	4	distilled	distil	VERB
gra-48	26	5	water	water	NOUN
gra-48	26	6	(	(	PUNCT
gra-48	26	7	5	5	NUM
gra-48	26	8	minutes	minute	NOUN
gra-48	26	9	)	)	PUNCT
gra-48	26	10	and	and	CCONJ
gra-48	26	11	in	in	ADP
gra-48	26	12	phosphate	phosphate	NOUN
gra-48	26	13	-	-	PUNCT
gra-48	26	14	buffered	buffer	VERB
gra-48	26	15	saline	saline	NOUN
gra-48	26	16	(	(	PUNCT
gra-48	26	17	pbs	pbs	PROPN
gra-48	26	18	)	)	PUNCT
gra-48	26	19	(	(	PUNCT
gra-48	26	20	5	5	NUM
gra-48	26	21	minutes	minute	NOUN
gra-48	26	22	)	)	PUNCT
gra-48	26	23	immersed	immerse	VERB
gra-48	26	24	in	in	ADP
gra-48	26	25	methanol	methanol	NOUN
gra-48	26	26	with	with	ADP
gra-48	26	27	0,3	0,3	NUM
gra-48	26	28	%	%	NOUN
gra-48	26	29	peroxidase	peroxidase	NOUN
gra-48	26	30	for	for	ADP
gra-48	26	31	5	5	NUM
gra-48	26	32	minutes	minute	NOUN
gra-48	26	33	to	to	PART
gra-48	26	34	inhibit	inhibit	VERB
gra-48	26	35	endogenous	endogenous	ADJ
gra-48	26	36	peroxidase	peroxidase	NOUN
gra-48	26	37	activity	activity	NOUN
gra-48	26	38	.	.	PUNCT
gra-48	27	1	antibody	antibody	NOUN
gra-48	27	2	was	be	AUX
gra-48	27	3	applied	apply	VERB
gra-48	27	4	,	,	PUNCT
gra-48	27	5	and	and	CCONJ
gra-48	27	6	incubations	incubation	NOUN
gra-48	27	7	were	be	AUX
gra-48	27	8	performed	perform	VERB
gra-48	27	9	2	2	NUM
gra-48	27	10	hours	hour	NOUN
gra-48	27	11	at	at	ADP
gra-48	27	12	room	room	NOUN
gra-48	27	13	temperature	temperature	NOUN
gra-48	27	14	.	.	PUNCT
gra-48	28	1	after	after	ADP
gra-48	28	2	washing	wash	VERB
gra-48	28	3	ve	ve	PROPN
gra-48	28	4	times	time	NOUN
gra-48	28	5	in	in	ADP
gra-48	28	6	pbs	pbs	PROPN
gra-48	28	7	,	,	PUNCT
gra-48	28	8	slides	slide	NOUN
gra-48	28	9	were	be	AUX
gra-48	28	10	incubated	incubate	VERB
gra-48	28	11	with	with	ADP
gra-48	28	12	biotinylated	biotinylated	ADJ
gra-48	28	13	second	second	ADJ
gra-48	28	14	antimouse	antimouse	ADP
gra-48	28	15	antibody	antibody	NOUN
gra-48	28	16	(	(	PUNCT
gra-48	28	17	zymed	zyme	VERB
gra-48	28	18	,	,	PUNCT
gra-48	28	19	diluted	dilute	VERB
gra-48	28	20	1:200	1:200	NUM
gra-48	28	21	)	)	PUNCT
gra-48	28	22	after	after	SCONJ
gra-48	28	23	ve	ve	PROPN
gra-48	28	24	washes	wash	VERB
gra-48	28	25	with	with	ADP
gra-48	28	26	washing	washing	NOUN
gra-48	28	27	buffer	buffer	NOUN
gra-48	28	28	,	,	PUNCT
gra-48	28	29	the	the	DET
gra-48	28	30	sections	section	NOUN
gra-48	28	31	were	be	AUX
gra-48	28	32	incubated	incubate	VERB
gra-48	28	33	with	with	ADP
gra-48	28	34	aec	aec	PROPN
gra-48	28	35	.	.	PUNCT
gra-48	29	1	the	the	DET
gra-48	29	2	sections	section	NOUN
gra-48	29	3	were	be	AUX
gra-48	29	4	counterstained	counterstaine	VERB
gra-48	29	5	with	with	ADP
gra-48	29	6	meyer	meyer	PROPN
gra-48	29	7	's	's	PART
gra-48	29	8	hematoxylin	hematoxylin	NOUN
gra-48	29	9	.	.	PUNCT
gra-48	30	1	evaluation	evaluation	NOUN
gra-48	30	2	of	of	ADP
gra-48	30	3	immunostaining	immunostaining	NOUN
gra-48	30	4	:	:	PUNCT
gra-48	30	5	mmp-2	mmp-2	ADJ
gra-48	30	6	expression	expression	NOUN
gra-48	30	7	:	:	PUNCT
gra-48	30	8	mmp-2	mmp-2	ADJ
gra-48	30	9	staining	stain	VERB
gra-48	30	10	was	be	AUX
gra-48	30	11	restricted	restrict	VERB
gra-48	30	12	to	to	ADP
gra-48	30	13	the	the	DET
gra-48	30	14	stromal	stromal	ADJ
gra-48	30	15	broblasts	broblast	NOUN
gra-48	30	16	and	and	CCONJ
gra-48	30	17	inammatory	inammatory	ADJ
gra-48	30	18	cell	cell	NOUN
gra-48	30	19	,	,	PUNCT
gra-48	30	20	with	with	ADP
gra-48	30	21	no	no	DET
gra-48	30	22	staining	staining	NOUN
gra-48	30	23	of	of	ADP
gra-48	30	24	evaluati̇on	evaluati̇on	PROPN
gra-48	30	25	of	of	ADP
gra-48	30	26	e	e	NOUN
gra-48	30	27	-	-	NOUN
gra-48	30	28	cadheri̇n	cadheri̇n	PROPN
gra-48	30	29	,	,	PUNCT
gra-48	30	30	mmp-2	mmp-2	VERB
gra-48	30	31	i̇n	i̇n	ADJ
gra-48	30	32	colorectal	colorectal	ADJ
gra-48	30	33	carci̇noma	carci̇noma	ADP
gra-48	30	34	original	original	ADJ
gra-48	30	35	research	research	NOUN
gra-48	30	36	paper	paper	NOUN
gra-48	30	37	hilal	hilal	PROPN
gra-48	30	38	erinanç	erinanç	PROPN
gra-48	30	39	*	*	PROPN
gra-48	30	40	baskent	baskent	PROPN
gra-48	30	41	university	university	NOUN
gra-48	30	42	,	,	PUNCT
gra-48	30	43	faculty	faculty	NOUN
gra-48	30	44	of	of	ADP
gra-48	30	45	medicine	medicine	NOUN
gra-48	30	46	,	,	PUNCT
gra-48	30	47	department	department	NOUN
gra-48	30	48	of	of	ADP
gra-48	30	49	pathology	pathology	PROPN
gra-48	30	50	*	*	PUNCT
gra-48	30	51	corresponding	correspond	VERB
gra-48	30	52	author	author	NOUN
gra-48	30	53	medicine	medicine	NOUN
gra-48	30	54	background	background	NOUN
gra-48	30	55	:	:	PUNCT
gra-48	30	56	colorectal	colorectal	ADJ
gra-48	30	57	cancer	cancer	NOUN
gra-48	30	58	pogression	pogression	NOUN
gra-48	30	59	is	be	AUX
gra-48	30	60	a	a	DET
gra-48	30	61	multistep	multistep	ADJ
gra-48	30	62	process	process	NOUN
gra-48	30	63	,	,	PUNCT
gra-48	30	64	in	in	ADP
gra-48	30	65	which	which	PRON
gra-48	30	66	many	many	ADJ
gra-48	30	67	genes	gene	NOUN
gra-48	30	68	and	and	CCONJ
gra-48	30	69	proteins	protein	NOUN
gra-48	30	70	are	be	AUX
gra-48	30	71	involved	involve	VERB
gra-48	30	72	.	.	PUNCT
gra-48	31	1	matrix	matrix	NOUN
gra-48	31	2	metalloproteinase	metalloproteinase	NOUN
gra-48	31	3	and	and	CCONJ
gra-48	31	4	loss	loss	NOUN
gra-48	31	5	of	of	ADP
gra-48	31	6	-	-	PUNCT
gra-48	31	7	e	e	NOUN
gra-48	31	8	-	-	NOUN
gra-48	31	9	cadherin	cadherin	NOUN
gra-48	31	10	has	have	AUX
gra-48	31	11	been	be	AUX
gra-48	31	12	considered	consider	VERB
gra-48	31	13	to	to	PART
gra-48	31	14	be	be	AUX
gra-48	31	15	associated	associate	VERB
gra-48	31	16	with	with	ADP
gra-48	31	17	cancer	cancer	NOUN
gra-48	31	18	invasion	invasion	NOUN
gra-48	31	19	and	and	CCONJ
gra-48	31	20	metastasis	metastasis	NOUN
gra-48	31	21	.	.	PUNCT
gra-48	32	1	in	in	ADP
gra-48	32	2	our	our	PRON
gra-48	32	3	study	study	NOUN
gra-48	32	4	,	,	PUNCT
gra-48	32	5	we	we	PRON
gra-48	32	6	aim	aim	VERB
gra-48	32	7	to	to	PART
gra-48	32	8	evaluate	evaluate	VERB
gra-48	32	9	the	the	DET
gra-48	32	10	expressions	expression	NOUN
gra-48	32	11	of	of	ADP
gra-48	32	12	e	e	NOUN
gra-48	32	13	-	-	NOUN
gra-48	32	14	cadherin	cadherin	NOUN
gra-48	32	15	and	and	CCONJ
gra-48	32	16	mmp-2	mmp-2	NOUN
gra-48	32	17	in	in	ADP
gra-48	32	18	colorectal	colorectal	ADJ
gra-48	32	19	carcinoma	carcinoma	NOUN
gra-48	32	20	.	.	PUNCT
gra-48	33	1	material	material	NOUN
gra-48	33	2	and	and	CCONJ
gra-48	33	3	methods	method	NOUN
gra-48	33	4	:	:	PUNCT
gra-48	33	5	expressions	expression	NOUN
gra-48	33	6	of	of	ADP
gra-48	33	7	ecadherin	ecadherin	NOUN
gra-48	33	8	and	and	CCONJ
gra-48	33	9	mmp-2	mmp-2	NOUN
gra-48	33	10	in	in	ADP
gra-48	33	11	specimens	specimen	NOUN
gra-48	33	12	from	from	ADP
gra-48	33	13	48	48	NUM
gra-48	33	14	colorectal	colorectal	ADJ
gra-48	33	15	adenocarcinomas	adenocarcinoma	NOUN
gra-48	33	16	(	(	PUNCT
gra-48	33	17	24	24	NUM
gra-48	33	18	classic	classic	ADJ
gra-48	33	19	adenocarcinomas	adenocarcinoma	NOUN
gra-48	33	20	and	and	CCONJ
gra-48	33	21	24	24	NUM
gra-48	33	22	mucinous	mucinous	ADJ
gra-48	33	23	adenocarcinomas	adenocarcinoma	NOUN
gra-48	33	24	)	)	PUNCT
gra-48	33	25	were	be	AUX
gra-48	33	26	detected	detect	VERB
gra-48	33	27	by	by	ADP
gra-48	33	28	immunohistochemistry	immunohistochemistry	NOUN
gra-48	33	29	.	.	PUNCT
gra-48	34	1	results	result	NOUN
gra-48	34	2	:	:	PUNCT
gra-48	34	3	mmp-2	mmp-2	NUM
gra-48	34	4	expression	expression	NOUN
gra-48	34	5	was	be	AUX
gra-48	34	6	found	find	VERB
gra-48	34	7	45,84	45,84	ADJ
gra-48	34	8	%	%	NOUN
gra-48	34	9	in	in	ADP
gra-48	34	10	classic	classic	ADJ
gra-48	34	11	adenocarcinoma	adenocarcinoma	NOUN
gra-48	34	12	while	while	SCONJ
gra-48	34	13	e	e	NOUN
gra-48	34	14	-	-	NOUN
gra-48	34	15	cadherin	cadherin	NOUN
gra-48	34	16	was	be	AUX
gra-48	34	17	found	find	VERB
gra-48	34	18	33,33	33,33	NUM
gra-48	34	19	%	%	NOUN
gra-48	34	20	in	in	ADP
gra-48	34	21	mucinous	mucinous	ADJ
gra-48	34	22	carcinomas	carcinoma	NOUN
gra-48	34	23	.	.	PUNCT
gra-48	35	1	conclusion	conclusion	NOUN
gra-48	35	2	:	:	PUNCT
gra-48	35	3	our	our	PRON
gra-48	35	4	ndings	nding	NOUN
gra-48	35	5	demonstrate	demonstrate	VERB
gra-48	35	6	that	that	SCONJ
gra-48	35	7	e	e	NOUN
gra-48	35	8	-	-	NOUN
gra-48	35	9	cadherin	cadherin	NOUN
gra-48	35	10	and	and	CCONJ
gra-48	35	11	mmp-2	mmp-2	DET
gra-48	35	12	expression	expression	NOUN
gra-48	35	13	contributes	contribute	VERB
gra-48	35	14	to	to	ADP
gra-48	35	15	tumor	tumor	NOUN
gra-48	35	16	development	development	NOUN
gra-48	35	17	.	.	PUNCT
gra-48	36	1	it	it	PRON
gra-48	36	2	sems	sem	VERB
gra-48	36	3	that	that	SCONJ
gra-48	36	4	mmp-2	mmp-2	NUM
gra-48	36	5	expression	expression	NOUN
gra-48	36	6	was	be	AUX
gra-48	36	7	more	more	ADV
gra-48	36	8	associated	associate	VERB
gra-48	36	9	with	with	ADP
gra-48	36	10	classic	classic	ADJ
gra-48	36	11	adenocarcinomas	adenocarcinoma	NOUN
gra-48	36	12	while	while	SCONJ
gra-48	36	13	e	e	NOUN
gra-48	36	14	-	-	NOUN
gra-48	36	15	cadherin	cadherin	NOUN
gra-48	36	16	was	be	AUX
gra-48	36	17	related	relate	VERB
gra-48	36	18	with	with	ADP
gra-48	36	19	mucinous	mucinous	ADJ
gra-48	36	20	adenocarcinomas	adenocarcinoma	NOUN
gra-48	36	21	.further	.further	ADP
gra-48	36	22	studies	study	NOUN
gra-48	36	23	are	be	AUX
gra-48	36	24	need	need	ADJ
gra-48	36	25	to	to	ADP
gra-48	36	26	nd	nd	DET
gra-48	36	27	the	the	DET
gra-48	36	28	correlations	correlation	NOUN
gra-48	36	29	between	between	ADP
gra-48	36	30	e	e	NOUN
gra-48	36	31	-	-	NOUN
gra-48	36	32	cadherin	cadherin	NOUN
gra-48	36	33	,	,	PUNCT
gra-48	36	34	mmp-2	mmp-2	NUM
gra-48	36	35	and	and	CCONJ
gra-48	36	36	epithelial	epithelial	ADJ
gra-48	36	37	-	-	PUNCT
gra-48	36	38	mesenchymal	mesenchymal	NOUN
gra-48	36	39	transition	transition	NOUN
gra-48	36	40	.	.	PUNCT
gra-48	37	1	abstract	abstract	ADJ
gra-48	37	2	keywords	keyword	NOUN
gra-48	37	3	:	:	PUNCT
gra-48	37	4	colorectal	colorectal	ADJ
gra-48	37	5	cancer	cancer	NOUN
gra-48	37	6	,	,	PUNCT
gra-48	37	7	e	e	NOUN
gra-48	37	8	-	-	NOUN
gra-48	37	9	cadherin	cadherin	NOUN
gra-48	37	10	,	,	PUNCT
gra-48	37	11	mmp-2	mmp-2	PROPN
gra-48	37	12	emin	emin	PROPN
gra-48	37	13	turk	turk	PROPN
gra-48	37	14	baskent	baskent	PROPN
gra-48	37	15	university	university	NOUN
gra-48	37	16	,	,	PUNCT
gra-48	37	17	faculty	faculty	NOUN
gra-48	37	18	of	of	ADP
gra-48	37	19	medicine	medicine	NOUN
gra-48	37	20	,	,	PUNCT
gra-48	37	21	department	department	NOUN
gra-48	37	22	of	of	ADP
gra-48	37	23	general	general	ADJ
gra-48	37	24	surgery	surgery	NOUN
gra-48	37	25	volume-8	volume-8	NUM
gra-48	37	26	,	,	PUNCT
gra-48	37	27	issue-9	issue-9	NUM
gra-48	37	28	,	,	PUNCT
gra-48	37	29	september-2019	september-2019	ADJ
gra-48	37	30	•	•	NUM
gra-48	37	31	print	print	NOUN
gra-48	37	32	issn	issn	PROPN
gra-48	37	33	no	no	NOUN
gra-48	37	34	.	.	PROPN
gra-48	37	35	2277	2277	NUM
gra-48	37	36	8160	8160	NUM
gra-48	37	37	•	•	NOUN
gra-48	37	38	doi	doi	NOUN
gra-48	37	39	:	:	PUNCT
gra-48	37	40	10.36106	10.36106	NUM
gra-48	37	41	/	/	SYM
gra-48	37	42	gjra	gjra	NOUN
gra-48	37	43	22	22	NUM
gra-48	37	44	x	x	NOUN
gra-48	37	45	gjra	gjra	PROPN
gra-48	37	46	global	global	ADJ
gra-48	37	47	journal	journal	PROPN
gra-48	37	48	for	for	ADP
gra-48	37	49	research	research	NOUN
gra-48	37	50	analysis	analysis	NOUN
gra-48	37	51	tumor	tumor	NOUN
gra-48	37	52	cells	cell	NOUN
gra-48	37	53	.	.	PUNCT
gra-48	38	1	staining	stain	VERB
gra-48	38	2	intensity	intensity	NOUN
gra-48	38	3	was	be	AUX
gra-48	38	4	graded	grade	VERB
gra-48	38	5	as	as	SCONJ
gra-48	38	6	follows	follow	VERB
gra-48	38	7	:	:	PUNCT
gra-48	38	8	0	0	NUM
gra-48	38	9	,	,	PUNCT
gra-48	38	10	no	no	DET
gra-48	38	11	staining	staining	NOUN
gra-48	38	12	;	;	PUNCT
gra-48	38	13	1	1	NUM
gra-48	38	14	,	,	PUNCT
gra-48	38	15	weak	weak	ADJ
gra-48	38	16	staining	staining	NOUN
gra-48	38	17	;	;	PUNCT
gra-48	38	18	2	2	NUM
gra-48	38	19	,	,	PUNCT
gra-48	38	20	moderate	moderate	ADJ
gra-48	38	21	staining	staining	NOUN
gra-48	38	22	;	;	PUNCT
gra-48	38	23	and	and	CCONJ
gra-48	38	24	3	3	NUM
gra-48	38	25	,	,	PUNCT
gra-48	38	26	intense	intense	ADJ
gra-48	38	27	staining	staining	NOUN
gra-48	38	28	.	.	PUNCT
gra-48	39	1	e	e	X
gra-48	39	2	-	-	NOUN
gra-48	39	3	cadherin	cadherin	NOUN
gra-48	39	4	expression	expression	NOUN
gra-48	39	5	:	:	PUNCT
gra-48	40	1	e	e	X
gra-48	40	2	-	-	NOUN
gra-48	40	3	cadherin	cadherin	NOUN
gra-48	40	4	immunoreactivity	immunoreactivity	NOUN
gra-48	40	5	was	be	AUX
gra-48	40	6	localized	localize	VERB
gra-48	40	7	in	in	ADP
gra-48	40	8	the	the	DET
gra-48	40	9	cytoplasm	cytoplasm	ADJ
gra-48	40	10	and	and	CCONJ
gra-48	40	11	plasma	plasma	NOUN
gra-48	40	12	membrane	membrane	NOUN
gra-48	40	13	in	in	ADP
gra-48	40	14	normal	normal	ADJ
gra-48	40	15	mucosa	mucosa	NOUN
gra-48	40	16	.	.	PUNCT
gra-48	41	1	cytoplasmic	cytoplasmic	ADJ
gra-48	41	2	expression	expression	NOUN
gra-48	41	3	of	of	ADP
gra-48	41	4	e	e	NOUN
gra-48	41	5	-	-	NOUN
gra-48	41	6	cadherin	cadherin	NOUN
gra-48	41	7	was	be	AUX
gra-48	41	8	recorded	record	VERB
gra-48	41	9	when	when	SCONJ
gra-48	41	10	staining	stain	VERB
gra-48	41	11	was	be	AUX
gra-48	41	12	absent	absent	ADJ
gra-48	41	13	from	from	ADP
gra-48	41	14	the	the	DET
gra-48	41	15	cancer	cancer	NOUN
gra-48	41	16	cell	cell	NOUN
gra-48	41	17	membrane	membrane	NOUN
gra-48	41	18	and	and	CCONJ
gra-48	41	19	preserved	preserve	VERB
gra-48	41	20	in	in	ADP
gra-48	41	21	cancer	cancer	NOUN
gra-48	41	22	cell	cell	NOUN
gra-48	41	23	cytoplasm	cytoplasm	NOUN
gra-48	41	24	and	and	CCONJ
gra-48	41	25	nucleus	nucleus	NOUN
gra-48	41	26	.	.	PUNCT
gra-48	42	1	(	(	PUNCT
gra-48	42	2	0	0	X
gra-48	42	3	)	)	PUNCT
gra-48	42	4	negative	negative	ADJ
gra-48	42	5	,	,	PUNCT
gra-48	42	6	no	no	DET
gra-48	42	7	detectable	detectable	ADJ
gra-48	42	8	staining	staining	NOUN
gra-48	42	9	.	.	PUNCT
gra-48	43	1	weak	weak	ADJ
gra-48	43	2	but	but	CCONJ
gra-48	43	3	detectable	detectable	ADJ
gra-48	43	4	discontinuous	discontinuous	ADJ
gra-48	43	5	staining	staining	NOUN
gra-48	43	6	graded	grade	VERB
gra-48	43	7	as	as	ADP
gra-48	43	8	(	(	PUNCT
gra-48	43	9	1	1	NUM
gra-48	43	10	)	)	PUNCT
gra-48	43	11	;	;	PUNCT
gra-48	43	12	moderate	moderate	ADJ
gra-48	43	13	,	,	PUNCT
gra-48	43	14	but	but	CCONJ
gra-48	43	15	discontinuous	discontinuous	ADJ
gra-48	43	16	staining	staining	NOUN
gra-48	43	17	graded	grade	VERB
gra-48	43	18	as(2	as(2	NOUN
gra-48	43	19	)	)	PUNCT
gra-48	43	20	;	;	PUNCT
gra-48	43	21	intense	intense	ADJ
gra-48	43	22	and	and	CCONJ
gra-48	43	23	continuous	continuous	ADJ
gra-48	43	24	staining	staining	NOUN
gra-48	43	25	graded	grade	VERB
gra-48	43	26	as	as	ADP
gra-48	43	27	(	(	PUNCT
gra-48	43	28	3	3	NUM
gra-48	43	29	)	)	PUNCT
gra-48	43	30	.	.	PUNCT
gra-48	44	1	statistical	statistical	ADJ
gra-48	44	2	analysis	analysis	NOUN
gra-48	44	3	the	the	DET
gra-48	44	4	associations	association	NOUN
gra-48	44	5	between	between	ADP
gra-48	44	6	expressions	expression	NOUN
gra-48	44	7	of	of	ADP
gra-48	44	8	the	the	DET
gra-48	44	9	two	two	NUM
gra-48	44	10	items	item	NOUN
gra-48	44	11	with	with	ADP
gra-48	44	12	clinicopathological	clinicopathological	ADJ
gra-48	44	13	variables	variable	NOUN
gra-48	44	14	were	be	AUX
gra-48	44	15	assessed	assess	VERB
gra-48	44	16	by	by	ADP
gra-48	44	17	chi	chi	ADJ
gra-48	44	18	-	-	PUNCT
gra-48	44	19	square	square	ADJ
gra-48	44	20	test	test	NOUN
gra-48	44	21	.	.	PUNCT
gra-48	45	1	p	p	X
gra-48	45	2	-	-	PUNCT
gra-48	45	3	values	value	NOUN
gra-48	45	4	were	be	AUX
gra-48	45	5	calculated	calculate	VERB
gra-48	45	6	with	with	ADP
gra-48	45	7	signicance	signicance	NOUN
gra-48	45	8	level	level	NOUN
gra-48	45	9	<	<	NOUN
gra-48	45	10	0.05	0.05	NUM
gra-48	45	11	.	.	PUNCT
gra-48	46	1	all	all	DET
gra-48	46	2	calculations	calculation	NOUN
gra-48	46	3	were	be	AUX
gra-48	46	4	performed	perform	VERB
gra-48	46	5	with	with	ADP
gra-48	46	6	spss	spss	PROPN
gra-48	46	7	software	software	NOUN
gra-48	46	8	package	package	NOUN
gra-48	46	9	,	,	PUNCT
gra-48	46	10	standard	standard	ADJ
gra-48	46	11	version	version	NOUN
gra-48	46	12	17.0	17.0	NUM
gra-48	46	13	(	(	PUNCT
gra-48	46	14	spss	spss	PROPN
gra-48	46	15	inc	inc	PROPN
gra-48	46	16	.	.	PROPN
gra-48	46	17	,	,	PUNCT
gra-48	46	18	chicago	chicago	PROPN
gra-48	46	19	,	,	PUNCT
gra-48	46	20	il	il	PROPN
gra-48	46	21	,	,	PUNCT
gra-48	46	22	usa	usa	PROPN
gra-48	46	23	)	)	PUNCT
gra-48	46	24	.	.	PUNCT
gra-48	47	1	results	result	NOUN
gra-48	47	2	:	:	PUNCT
gra-48	47	3	mmp-2	mmp-2	ADJ
gra-48	47	4	staining	stain	VERB
gra-48	47	5	:	:	PUNCT
gra-48	47	6	mmp-2	mmp-2	NUM
gra-48	47	7	was	be	AUX
gra-48	47	8	localized	localize	VERB
gra-48	47	9	in	in	ADP
gra-48	47	10	stromal	stromal	ADJ
gra-48	47	11	broblast	broblast	NOUN
gra-48	47	12	in	in	ADP
gra-48	47	13	colon	colon	NOUN
gra-48	47	14	adenocarcinomas	adenocarcinoma	NOUN
gra-48	47	15	(	(	PUNCT
gra-48	47	16	figurei	figurei	NOUN
gra-48	47	17	)	)	PUNCT
gra-48	47	18	.	.	PUNCT
gra-48	48	1	mmp-2	mmp-2	VERB
gra-48	48	2	staining	stain	VERB
gra-48	48	3	was	be	AUX
gra-48	48	4	also	also	ADV
gra-48	48	5	weakly	weakly	ADV
gra-48	48	6	observed	observed	ADJ
gra-48	48	7	in	in	ADP
gra-48	48	8	inammatory	inammatory	ADJ
gra-48	48	9	cells	cell	NOUN
gra-48	48	10	,	,	PUNCT
gra-48	48	11	macrophages	macrophage	NOUN
gra-48	48	12	,	,	PUNCT
gra-48	48	13	endothelial	endothelial	ADJ
gra-48	48	14	cells	cell	NOUN
gra-48	48	15	and	and	CCONJ
gra-48	48	16	muscularis	muscularis	NOUN
gra-48	48	17	mucosa	mucosa	NOUN
gra-48	48	18	.	.	PUNCT
gra-48	49	1	while	while	SCONJ
gra-48	49	2	mmp-2	mmp-2	ADV
gra-48	49	3	was	be	AUX
gra-48	49	4	weakly	weakly	ADV
gra-48	49	5	expressed	express	VERB
gra-48	49	6	in	in	ADP
gra-48	49	7	21,7	21,7	NUM
gra-48	49	8	%	%	NOUN
gra-48	49	9	of	of	ADP
gra-48	49	10	normal	normal	ADJ
gra-48	49	11	mucosa	mucosa	NOUN
gra-48	49	12	,	,	PUNCT
gra-48	49	13	higher	high	ADJ
gra-48	49	14	expression	expression	NOUN
gra-48	49	15	seen	see	VERB
gra-48	49	16	in	in	ADP
gra-48	49	17	45,84	45,84	ADJ
gra-48	49	18	%	%	NOUN
gra-48	49	19	of	of	ADP
gra-48	49	20	classic	classic	ADJ
gra-48	49	21	adenocarcinomas	adenocarcinoma	NOUN
gra-48	49	22	.	.	PUNCT
gra-48	50	1	in	in	ADP
gra-48	50	2	mucinous	mucinous	ADJ
gra-48	50	3	tumors	tumor	NOUN
gra-48	50	4	,	,	PUNCT
gra-48	50	5	the	the	DET
gra-48	50	6	rate	rate	NOUN
gra-48	50	7	of	of	ADP
gra-48	50	8	positive	positive	ADJ
gra-48	50	9	cases	case	NOUN
gra-48	50	10	were	be	AUX
gra-48	50	11	similar	similar	ADJ
gra-48	50	12	to	to	ADP
gra-48	50	13	normal	normal	ADJ
gra-48	50	14	mucosa	mucosa	NOUN
gra-48	50	15	.	.	PUNCT
gra-48	51	1	the	the	DET
gra-48	51	2	staining	stain	VERB
gra-48	51	3	intensity	intensity	NOUN
gra-48	51	4	was	be	AUX
gra-48	51	5	scored	score	VERB
gra-48	51	6	as	as	ADP
gra-48	51	7	(	(	PUNCT
gra-48	51	8	range	range	NOUN
gra-48	51	9	:	:	PUNCT
gra-48	51	10	0	0	NUM
gra-48	51	11	to	to	PART
gra-48	51	12	3	3	NUM
gra-48	51	13	)	)	PUNCT
gra-48	51	14	and	and	CCONJ
gra-48	51	15	the	the	DET
gra-48	51	16	percentage	percentage	NOUN
gra-48	51	17	of	of	ADP
gra-48	51	18	positive	positive	ADJ
gra-48	51	19	casess	casess	NOUN
gra-48	51	20	as	as	ADP
gra-48	51	21	(	(	PUNCT
gra-48	51	22	range	range	NOUN
gra-48	51	23	:	:	PUNCT
gra-48	51	24	0	0	NUM
gra-48	51	25	to	to	ADP
gra-48	51	26	3	3	NUM
gra-48	51	27	[	[	X
gra-48	51	28	0	0	NUM
gra-48	51	29	,	,	PUNCT
gra-48	51	30	{	{	PUNCT
gra-48	51	31	n:13	n:13	VERB
gra-48	51	32	,	,	PUNCT
gra-48	51	33	54,16	54,16	NUM
gra-48	51	34	%	%	NOUN
gra-48	51	35	}	}	PUNCT
gra-48	51	36	,	,	PUNCT
gra-48	51	37	1	1	NUM
gra-48	51	38	{	{	PUNCT
gra-48	51	39	n:8,%33,3	n:8,%33,3	NUM
gra-48	51	40	%	%	NOUN
gra-48	51	41	}	}	PUNCT
gra-48	51	42	,	,	PUNCT
gra-48	51	43	2	2	NUM
gra-48	51	44	{	{	PUNCT
gra-48	51	45	n:2	n:2	PROPN
gra-48	51	46	,	,	PUNCT
gra-48	51	47	%	%	NOUN
gra-48	51	48	8,33	8,33	NUM
gra-48	51	49	%	%	NOUN
gra-48	51	50	}	}	PUNCT
gra-48	51	51	,	,	PUNCT
gra-48	51	52	3	3	NUM
gra-48	51	53	{	{	PUNCT
gra-48	51	54	n.1	n.1	NUM
gra-48	51	55	,	,	PUNCT
gra-48	51	56	4,16	4,16	NUM
gra-48	51	57	%	%	NOUN
gra-48	51	58	}	}	PUNCT
gra-48	51	59	]	]	PUNCT
gra-48	51	60	)	)	PUNCT
gra-48	51	61	.	.	PUNCT
gra-48	52	1	the	the	DET
gra-48	52	2	mean	mean	ADJ
gra-48	52	3	level	level	NOUN
gra-48	52	4	of	of	ADP
gra-48	52	5	mmp-2	mmp-2	NUM
gra-48	52	6	was	be	AUX
gra-48	52	7	between	between	ADP
gra-48	52	8	0,200,52	0,200,52	PROPN
gra-48	52	9	and	and	CCONJ
gra-48	52	10	1,661,41	1,661,41	NUM
gra-48	52	11	.	.	PUNCT
gra-48	53	1	staining	stain	VERB
gra-48	53	2	was	be	AUX
gra-48	53	3	increased	increase	VERB
gra-48	53	4	from	from	ADP
gra-48	53	5	normal	normal	ADJ
gra-48	53	6	mucosa	mucosa	NOUN
gra-48	53	7	(	(	PUNCT
gra-48	53	8	0,621,03	0,621,03	PROPN
gra-48	53	9	)	)	PUNCT
gra-48	53	10	to	to	ADP
gra-48	53	11	carcinomas	carcinomas	PROPN
gra-48	53	12	group	group	NOUN
gra-48	53	13	(	(	PUNCT
gra-48	53	14	0,730,98	0,730,98	PROPN
gra-48	53	15	)	)	PUNCT
gra-48	53	16	however	however	ADV
gra-48	53	17	there	there	PRON
gra-48	53	18	was	be	VERB
gra-48	53	19	no	no	DET
gra-48	53	20	statistical	statistical	ADJ
gra-48	53	21	difference	difference	NOUN
gra-48	53	22	.	.	PUNCT
gra-48	54	1	there	there	PRON
gra-48	54	2	was	be	VERB
gra-48	54	3	no	no	DET
gra-48	54	4	correlation	correlation	NOUN
gra-48	54	5	between	between	ADP
gra-48	54	6	mmp-2	mmp-2	ADJ
gra-48	54	7	staining	staining	ADJ
gra-48	54	8	and	and	CCONJ
gra-48	54	9	tumor	tumor	NOUN
gra-48	54	10	grade	grade	NOUN
gra-48	54	11	and	and	CCONJ
gra-48	54	12	stage	stage	NOUN
gra-48	54	13	.	.	PUNCT
gra-48	55	1	table	table	NOUN
gra-48	55	2	i	i	PRON
gra-48	55	3	shows	show	VERB
gra-48	55	4	mmp-2	mmp-2	NUM
gra-48	55	5	expression	expression	NOUN
gra-48	55	6	according	accord	VERB
gra-48	55	7	to	to	ADP
gra-48	55	8	staining	stain	VERB
gra-48	55	9	intensity	intensity	NOUN
gra-48	55	10	.	.	PUNCT
gra-48	56	1	e	e	X
gra-48	56	2	-	-	NOUN
gra-48	56	3	cadherin	cadherin	NOUN
gra-48	56	4	staining	staining	NOUN
gra-48	56	5	:	:	PUNCT
gra-48	56	6	all	all	PRON
gra-48	56	7	of	of	ADP
gra-48	56	8	the	the	DET
gra-48	56	9	classic	classic	ADJ
gra-48	56	10	adenocarcinomas	adenocarcinoma	NOUN
gra-48	56	11	showed	show	VERB
gra-48	56	12	the	the	DET
gra-48	56	13	membranous	membranous	ADJ
gra-48	56	14	and	and	CCONJ
gra-48	56	15	cytoplasmic	cytoplasmic	ADJ
gra-48	56	16	expression	expression	NOUN
gra-48	56	17	pattern	pattern	NOUN
gra-48	56	18	of	of	ADP
gra-48	56	19	e	e	NOUN
gra-48	56	20	-	-	NOUN
gra-48	56	21	cadherin	cadherin	NOUN
gra-48	56	22	(	(	PUNCT
gra-48	56	23	figure	figure	NOUN
gra-48	56	24	ii	ii	PROPN
gra-48	56	25	)	)	PUNCT
gra-48	56	26	.	.	PUNCT
gra-48	57	1	of	of	ADP
gra-48	57	2	the	the	DET
gra-48	57	3	24	24	NUM
gra-48	57	4	tumors	tumor	NOUN
gra-48	57	5	,	,	PUNCT
gra-48	57	6	12	12	NUM
gra-48	57	7	(	(	PUNCT
gra-48	57	8	50	50	NUM
gra-48	57	9	%	%	NOUN
gra-48	57	10	)	)	PUNCT
gra-48	57	11	were	be	AUX
gra-48	57	12	considered	consider	VERB
gra-48	57	13	as	as	SCONJ
gra-48	57	14	grade	grade	NOUN
gra-48	57	15	3	3	NUM
gra-48	57	16	staining	stain	VERB
gra-48	57	17	intensity	intensity	NOUN
gra-48	57	18	and	and	CCONJ
gra-48	57	19	12	12	NUM
gra-48	57	20	(	(	PUNCT
gra-48	57	21	50	50	NUM
gra-48	57	22	)	)	PUNCT
gra-48	57	23	were	be	AUX
gra-48	57	24	considered	consider	VERB
gra-48	57	25	as	as	ADP
gra-48	57	26	grade	grade	NOUN
gra-48	57	27	2	2	NUM
gra-48	57	28	staining	stain	VERB
gra-48	57	29	intensity	intensity	NOUN
gra-48	57	30	.	.	PUNCT
gra-48	58	1	there	there	PRON
gra-48	58	2	were	be	VERB
gra-48	58	3	no	no	DET
gra-48	58	4	decreased	decrease	VERB
gra-48	58	5	in	in	ADP
gra-48	58	6	e	e	NOUN
gra-48	58	7	-	-	NOUN
gra-48	58	8	cadherin	cadherin	NOUN
gra-48	58	9	expression	expression	NOUN
gra-48	58	10	in	in	ADP
gra-48	58	11	classic	classic	ADJ
gra-48	58	12	adenocarcinomas	adenocarcinoma	NOUN
gra-48	58	13	.	.	PUNCT
gra-48	59	1	loss	loss	NOUN
gra-48	59	2	of	of	ADP
gra-48	59	3	e	e	NOUN
gra-48	59	4	-	-	NOUN
gra-48	59	5	cadherin	cadherin	NOUN
gra-48	59	6	expression	expression	NOUN
gra-48	59	7	was	be	AUX
gra-48	59	8	seen	see	VERB
gra-48	59	9	in	in	ADP
gra-48	59	10	33,33	33,33	NUM
gra-48	59	11	%	%	NOUN
gra-48	59	12	of	of	ADP
gra-48	59	13	patients	patient	NOUN
gra-48	59	14	with	with	ADP
gra-48	59	15	mucinous	mucinous	ADJ
gra-48	59	16	tumors	tumor	NOUN
gra-48	59	17	(	(	PUNCT
gra-48	59	18	figure	figure	NOUN
gra-48	59	19	iii	iii	NOUN
gra-48	59	20	)	)	PUNCT
gra-48	59	21	.	.	PUNCT
gra-48	60	1	of	of	ADP
gra-48	60	2	the	the	DET
gra-48	60	3	24	24	NUM
gra-48	60	4	tumors	tumor	NOUN
gra-48	60	5	,	,	PUNCT
gra-48	60	6	16	16	NUM
gra-48	60	7	patient	patient	NOUN
gra-48	60	8	(	(	PUNCT
gra-48	60	9	66,67	66,67	NUM
gra-48	60	10	%	%	NOUN
gra-48	60	11	)	)	PUNCT
gra-48	60	12	were	be	AUX
gra-48	60	13	considered	consider	VERB
gra-48	60	14	as	as	SCONJ
gra-48	60	15	grade	grade	NOUN
gra-48	60	16	3	3	NUM
gra-48	60	17	staining	stain	VERB
gra-48	60	18	intensity	intensity	NOUN
gra-48	60	19	and	and	CCONJ
gra-48	60	20	8	8	NUM
gra-48	60	21	patient	patient	NOUN
gra-48	60	22	(	(	PUNCT
gra-48	60	23	33,33	33,33	NUM
gra-48	60	24	%	%	NOUN
gra-48	60	25	)	)	PUNCT
gra-48	60	26	were	be	AUX
gra-48	60	27	considered	consider	VERB
gra-48	60	28	as	as	ADP
gra-48	60	29	grade	grade	NOUN
gra-48	60	30	0	0	NUM
gra-48	60	31	.	.	PUNCT
gra-48	60	32	table	table	NOUN
gra-48	60	33	ii	ii	PROPN
gra-48	60	34	shows	show	VERB
gra-48	60	35	e	e	NOUN
gra-48	60	36	-	-	NOUN
gra-48	60	37	cadherin	cadherin	NOUN
gra-48	60	38	expression	expression	NOUN
gra-48	60	39	according	accord	VERB
gra-48	60	40	to	to	ADP
gra-48	60	41	staining	stain	VERB
gra-48	60	42	intensity	intensity	NOUN
gra-48	60	43	.	.	PUNCT
gra-48	61	1	di̇scussi̇on	di̇scussi̇on	VERB
gra-48	61	2	:	:	PUNCT
gra-48	61	3	in	in	ADP
gra-48	61	4	this	this	DET
gra-48	61	5	study	study	NOUN
gra-48	61	6	,	,	PUNCT
gra-48	61	7	we	we	PRON
gra-48	61	8	evaluated	evaluate	VERB
gra-48	61	9	the	the	DET
gra-48	61	10	expressions	expression	NOUN
gra-48	61	11	of	of	ADP
gra-48	61	12	e	e	NOUN
gra-48	61	13	-	-	NOUN
gra-48	61	14	cadherin	cadherin	NOUN
gra-48	61	15	and	and	CCONJ
gra-48	61	16	mmp-2	mmp-2	ADJ
gra-48	61	17	and	and	CCONJ
gra-48	61	18	their	their	PRON
gra-48	61	19	relation	relation	NOUN
gra-48	61	20	with	with	ADP
gra-48	61	21	clinocopathologic	clinocopathologic	ADJ
gra-48	61	22	features	feature	NOUN
gra-48	61	23	.	.	PUNCT
gra-48	62	1	numerous	numerous	ADJ
gra-48	62	2	studies	study	NOUN
gra-48	62	3	were	be	AUX
gra-48	62	4	performed	perform	VERB
gra-48	62	5	to	to	PART
gra-48	62	6	determine	determine	VERB
gra-48	62	7	how	how	SCONJ
gra-48	62	8	mmps	mmp	NOUN
gra-48	62	9	contribute	contribute	VERB
gra-48	62	10	to	to	ADP
gra-48	62	11	colorectal	colorectal	ADJ
gra-48	62	12	carcinogenesis	carcinogenesis	NOUN
gra-48	62	13	.	.	PUNCT
gra-48	63	1	in	in	ADP
gra-48	63	2	colorectal	colorectal	ADJ
gra-48	63	3	cancer	cancer	NOUN
gra-48	63	4	,	,	PUNCT
gra-48	63	5	mmp-7	mmp-7	X
gra-48	63	6	(	(	PUNCT
gra-48	63	7	matrilysin	matrilysin	NOUN
gra-48	63	8	)	)	PUNCT
gra-48	63	9	,	,	PUNCT
gra-48	63	10	mmp-2(gelatinase	mmp-2(gelatinase	NOUN
gra-48	63	11	a	a	PRON
gra-48	63	12	)	)	PUNCT
gra-48	63	13	,	,	PUNCT
gra-48	63	14	mmp-9(gelatinase	mmp-9(gelatinase	PROPN
gra-48	63	15	b	b	X
gra-48	63	16	)	)	PUNCT
gra-48	63	17	and	and	CCONJ
gra-48	63	18	mmp-1	mmp-1	PART
gra-48	63	19	have	have	AUX
gra-48	63	20	demonstrated	demonstrate	VERB
gra-48	63	21	to	to	PART
gra-48	63	22	be	be	AUX
gra-48	63	23	overexpressed	overexpresse	VERB
gra-48	63	24	(	(	PUNCT
gra-48	63	25	46,14	46,14	ADV
gra-48	63	26	-	-	SYM
gra-48	63	27	16	16	NUM
gra-48	63	28	)	)	PUNCT
gra-48	63	29	.	.	PUNCT
gra-48	64	1	mmp-2	mmp-2	PUNCT
gra-48	64	2	has	have	VERB
gra-48	64	3	the	the	DET
gra-48	64	4	ability	ability	NOUN
gra-48	64	5	to	to	PART
gra-48	64	6	degrade	degrade	VERB
gra-48	64	7	basement	basement	NOUN
gra-48	64	8	mem	mem	ADJ
gra-48	64	9	brane	brane	NOUN
gra-48	64	10	type	type	NOUN
gra-48	64	11	iv	iv	NUM
gra-48	64	12	collagen	collagen	NOUN
gra-48	64	13	,	,	PUNCT
gra-48	64	14	which	which	PRON
gra-48	64	15	would	would	AUX
gra-48	64	16	facilitate	facilitate	VERB
gra-48	64	17	tumor	tumor	NOUN
gra-48	64	18	cells	cell	NOUN
gra-48	64	19	invasion	invasion	NOUN
gra-48	64	20	.	.	PUNCT
gra-48	65	1	the	the	DET
gra-48	65	2	present	present	ADJ
gra-48	65	3	study	study	NOUN
gra-48	65	4	showed	show	VERB
gra-48	65	5	that	that	SCONJ
gra-48	65	6	the	the	DET
gra-48	65	7	expression	expression	NOUN
gra-48	65	8	of	of	ADP
gra-48	65	9	mmp-2	mmp-2	NUM
gra-48	65	10	was	be	AUX
gra-48	65	11	higher	high	ADJ
gra-48	65	12	compare	compare	NOUN
gra-48	65	13	to	to	ADP
gra-48	65	14	normal	normal	ADJ
gra-48	65	15	mucosa	mucosa	NOUN
gra-48	65	16	however	however	ADV
gra-48	65	17	its	its	PRON
gra-48	65	18	correlation	correlation	NOUN
gra-48	65	19	with	with	ADP
gra-48	65	20	tumor	tumor	NOUN
gra-48	65	21	stage	stage	NOUN
gra-48	65	22	and	and	CCONJ
gra-48	65	23	grade	grade	NOUN
gra-48	65	24	was	be	AUX
gra-48	65	25	not	not	PART
gra-48	65	26	obtained	obtain	VERB
gra-48	65	27	.	.	PUNCT
gra-48	66	1	studies	study	NOUN
gra-48	66	2	on	on	ADP
gra-48	66	3	the	the	DET
gra-48	66	4	functions	function	NOUN
gra-48	66	5	of	of	ADP
gra-48	66	6	mmp-2	mmp-2	NUM
gra-48	66	7	in	in	ADP
gra-48	66	8	cancer	cancer	NOUN
gra-48	66	9	progression	progression	NOUN
gra-48	66	10	were	be	AUX
gra-48	66	11	quite	quite	ADV
gra-48	66	12	controversial	controversial	ADJ
gra-48	66	13	waas	waas	NOUN
gra-48	66	14	and	and	CCONJ
gra-48	66	15	colleagues	colleague	NOUN
gra-48	66	16	similarly	similarly	ADV
gra-48	66	17	showed	show	VERB
gra-48	66	18	.	.	PUNCT
gra-48	67	1	that	that	DET
gra-48	67	2	low	low	ADJ
gra-48	67	3	stage	stage	NOUN
gra-48	67	4	(	(	PUNCT
gra-48	67	5	i	i	NOUN
gra-48	67	6	and	and	CCONJ
gra-48	67	7	ii	ii	NOUN
gra-48	67	8	)	)	PUNCT
gra-48	67	9	disease	disease	NOUN
gra-48	67	10	showed	show	VERB
gra-48	67	11	higher	high	ADJ
gra-48	67	12	mmp2	mmp2	ADJ
gra-48	67	13	expression	expression	NOUN
gra-48	67	14	than	than	ADP
gra-48	67	15	more	more	ADV
gra-48	67	16	advanced	advanced	ADJ
gra-48	67	17	stages	stage	NOUN
gra-48	67	18	(	(	PUNCT
gra-48	67	19	iii	iii	NOUN
gra-48	67	20	and	and	CCONJ
gra-48	67	21	iv	iv	X
gra-48	67	22	)	)	PUNCT
gra-48	67	23	(	(	PUNCT
gra-48	67	24	17	17	NUM
gra-48	67	25	)	)	PUNCT
gra-48	67	26	.	.	PUNCT
gra-48	68	1	wong	wong	PROPN
gra-48	68	2	et	et	PROPN
gra-48	68	3	al	al	PROPN
gra-48	68	4	demonstrated	demonstrate	VERB
gra-48	68	5	that	that	SCONJ
gra-48	68	6	lack	lack	NOUN
gra-48	68	7	of	of	ADP
gra-48	68	8	mmp2	mmp2	ADJ
gra-48	68	9	expression	expression	NOUN
gra-48	68	10	was	be	AUX
gra-48	68	11	associated	associate	VERB
gra-48	68	12	with	with	ADP
gra-48	68	13	poorer	poor	ADJ
gra-48	68	14	outcomes	outcome	NOUN
gra-48	68	15	in	in	ADP
gra-48	68	16	stage	stage	NOUN
gra-48	68	17	iii	iii	NUM
gra-48	68	18	rectal	rectal	ADJ
gra-48	68	19	cancers	cancer	NOUN
gra-48	68	20	,	,	PUNCT
gra-48	68	21	including	include	VERB
gra-48	68	22	the	the	DET
gra-48	68	23	risk	risk	NOUN
gra-48	68	24	of	of	ADP
gra-48	68	25	local	local	ADJ
gra-48	68	26	recurrence	recurrence	NOUN
gra-48	68	27	(	(	PUNCT
gra-48	68	28	18	18	NUM
gra-48	68	29	)	)	PUNCT
gra-48	68	30	.	.	PUNCT
gra-48	69	1	matrix	matrix	NOUN
gra-48	69	2	metalloproteinases	metalloproteinase	NOUN
gra-48	69	3	are	be	AUX
gra-48	69	4	synthesized	synthesize	VERB
gra-48	69	5	by	by	ADP
gra-48	69	6	neoplastic	neoplastic	ADJ
gra-48	69	7	and	and	CCONJ
gra-48	69	8	stromal	stromal	ADJ
gra-48	69	9	cells	cell	NOUN
gra-48	69	10	(	(	PUNCT
gra-48	69	11	19	19	NUM
gra-48	69	12	)	)	PUNCT
gra-48	69	13	in	in	ADP
gra-48	69	14	the	the	DET
gra-48	69	15	present	present	ADJ
gra-48	69	16	stuy	stuy	NOUN
gra-48	69	17	the	the	DET
gra-48	69	18	source	source	NOUN
gra-48	69	19	of	of	ADP
gra-48	69	20	mmp-2	mmp-2	NUM
gra-48	69	21	was	be	AUX
gra-48	69	22	only	only	ADV
gra-48	69	23	broblasts	broblast	NOUN
gra-48	69	24	and	and	CCONJ
gra-48	69	25	inammatory	inammatory	ADJ
gra-48	69	26	cells	cell	NOUN
gra-48	69	27	.	.	PUNCT
gra-48	70	1	our	our	PRON
gra-48	70	2	research	research	NOUN
gra-48	70	3	has	have	AUX
gra-48	70	4	demonstrated	demonstrate	VERB
gra-48	70	5	that	that	SCONJ
gra-48	70	6	weak	weak	ADJ
gra-48	70	7	expression	expression	NOUN
gra-48	70	8	of	of	ADP
gra-48	70	9	mmp2	mmp2	NOUN
gra-48	70	10	in	in	ADP
gra-48	70	11	the	the	DET
gra-48	70	12	inammatory	inammatory	ADJ
gra-48	70	13	inltration	inltration	NOUN
gra-48	70	14	and	and	CCONJ
gra-48	70	15	a	a	DET
gra-48	70	16	much	much	ADV
gra-48	70	17	stronger	strong	ADJ
gra-48	70	18	response	response	NOUN
gra-48	70	19	in	in	ADP
gra-48	70	20	stromal	stromal	ADJ
gra-48	70	21	broblast	broblast	NOUN
gra-48	70	22	in	in	ADP
gra-48	70	23	tumor	tumor	NOUN
gra-48	70	24	tissue	tissue	NOUN
gra-48	70	25	.	.	PUNCT
gra-48	71	1	groblewska	groblewska	NOUN
gra-48	71	2	et	et	PROPN
gra-48	71	3	al	al	PROPN
gra-48	71	4	found	find	VERB
gra-48	71	5	a	a	DET
gra-48	71	6	signicant	signicant	ADJ
gra-48	71	7	correlation	correlation	NOUN
gra-48	71	8	between	between	ADP
gra-48	71	9	mmp-2	mmp-2	PUNCT
gra-48	71	10	immunoreactivity	immunoreactivity	NOUN
gra-48	71	11	in	in	ADP
gra-48	71	12	inammatory	inammatory	ADJ
gra-48	71	13	cells	cell	NOUN
gra-48	71	14	and	and	CCONJ
gra-48	71	15	the	the	DET
gra-48	71	16	presence	presence	NOUN
gra-48	71	17	of	of	ADP
gra-48	71	18	distant	distant	ADJ
gra-48	71	19	metastases	metastasis	NOUN
gra-48	71	20	.	.	PUNCT
gra-48	72	1	(	(	PUNCT
gra-48	72	2	20	20	NUM
gra-48	72	3	)	)	PUNCT
gra-48	72	4	in	in	ADP
gra-48	72	5	the	the	DET
gra-48	72	6	present	present	ADJ
gra-48	72	7	study	study	NOUN
gra-48	72	8	mmp-2	mmp-2	DET
gra-48	72	9	expression	expression	NOUN
gra-48	72	10	was	be	AUX
gra-48	72	11	mostly	mostly	ADV
gra-48	72	12	seen	see	VERB
gra-48	72	13	in	in	ADP
gra-48	72	14	classic	classic	ADJ
gra-48	72	15	adenocarcinomas	adenocarcinoma	NOUN
gra-48	72	16	while	while	SCONJ
gra-48	72	17	stromal	stromal	ADJ
gra-48	72	18	mmp-2	mmp-2	ADJ
gra-48	72	19	expression	expression	NOUN
gra-48	72	20	could	could	AUX
gra-48	72	21	not	not	PART
gra-48	72	22	obtained	obtain	VERB
gra-48	72	23	in	in	ADP
gra-48	72	24	majority	majority	NOUN
gra-48	72	25	of	of	ADP
gra-48	72	26	mucinous	mucinous	ADJ
gra-48	72	27	tumors	tumor	NOUN
gra-48	72	28	.	.	PUNCT
gra-48	73	1	we	we	PRON
gra-48	73	2	thought	think	VERB
gra-48	73	3	that	that	SCONJ
gra-48	73	4	mmp-2	mmp-2	X
gra-48	73	5	expression	expression	NOUN
gra-48	73	6	coul	coul	PROPN
gra-48	73	7	not	not	PART
gra-48	73	8	pooperly	pooperly	ADV
gra-48	73	9	evaluated	evaluate	VERB
gra-48	73	10	due	due	ADP
gra-48	73	11	to	to	ADP
gra-48	73	12	mucinous	mucinous	ADJ
gra-48	73	13	nature	nature	NOUN
gra-48	73	14	of	of	ADP
gra-48	73	15	stroma	stroma	NOUN
gra-48	73	16	in	in	ADP
gra-48	73	17	mucinous	mucinous	ADJ
gra-48	73	18	tumors	tumor	NOUN
gra-48	73	19	.	.	PUNCT
gra-48	74	1	cellular	cellular	ADJ
gra-48	74	2	adhesion	adhesion	NOUN
gra-48	74	3	molecules	molecule	NOUN
gra-48	74	4	also	also	ADV
gra-48	74	5	plays	play	VERB
gra-48	74	6	an	an	DET
gra-48	74	7	important	important	ADJ
gra-48	74	8	role	role	NOUN
gra-48	74	9	in	in	ADP
gra-48	74	10	the	the	DET
gra-48	74	11	invasion	invasion	NOUN
gra-48	74	12	and	and	CCONJ
gra-48	74	13	metastasis	metastasis	NOUN
gra-48	74	14	of	of	ADP
gra-48	74	15	the	the	DET
gra-48	74	16	tumour	tumour	NOUN
gra-48	74	17	(	(	PUNCT
gra-48	74	18	21	21	NUM
gra-48	74	19	)	)	PUNCT
gra-48	74	20	loss	loss	NOUN
gra-48	74	21	of	of	ADP
gra-48	74	22	ecadherin	ecadherin	NOUN
gra-48	74	23	expression	expression	NOUN
gra-48	74	24	was	be	AUX
gra-48	74	25	reported	report	VERB
gra-48	74	26	to	to	PART
gra-48	74	27	promote	promote	VERB
gra-48	74	28	cancer	cancer	NOUN
gra-48	74	29	cell	cell	NOUN
gra-48	74	30	proliferation	proliferation	NOUN
gra-48	74	31	and	and	CCONJ
gra-48	74	32	invasion	invasion	NOUN
gra-48	74	33	and	and	CCONJ
gra-48	74	34	proved	prove	VERB
gra-48	74	35	to	to	PART
gra-48	74	36	correlate	correlate	VERB
gra-48	74	37	with	with	ADP
gra-48	74	38	cancer	cancer	NOUN
gra-48	74	39	progression	progression	NOUN
gra-48	74	40	and	and	CCONJ
gra-48	74	41	unfavorable	unfavorable	ADJ
gra-48	74	42	prognosis	prognosis	NOUN
gra-48	74	43	in	in	ADP
gra-48	74	44	various	various	ADJ
gra-48	74	45	cancer	cancer	NOUN
gra-48	74	46	.	.	PUNCT
gra-48	75	1	(	(	PUNCT
gra-48	75	2	22,23,24	22,23,24	NUM
gra-48	75	3	)	)	PUNCT
gra-48	75	4	loss	loss	NOUN
gra-48	75	5	of	of	ADP
gra-48	75	6	e	e	NOUN
gra-48	75	7	-	-	NOUN
gra-48	75	8	cadherin	cadherin	NOUN
gra-48	75	9	has	have	AUX
gra-48	75	10	been	be	AUX
gra-48	75	11	associated	associate	VERB
gra-48	75	12	with	with	ADP
gra-48	75	13	colorectal	colorectal	ADJ
gra-48	75	14	cancer	cancer	NOUN
gra-48	75	15	,	,	PUNCT
gra-48	75	16	before	before	ADP
gra-48	75	17	(	(	PUNCT
gra-48	75	18	25	25	NUM
gra-48	75	19	)	)	PUNCT
gra-48	75	20	.	.	PUNCT
gra-48	76	1	however	however	ADV
gra-48	76	2	conicting	conicte	VERB
gra-48	76	3	results	result	NOUN
gra-48	76	4	exist	exist	VERB
gra-48	76	5	on	on	ADP
gra-48	76	6	the	the	DET
gra-48	76	7	role	role	NOUN
gra-48	76	8	of	of	ADP
gra-48	76	9	e	e	NOUN
gra-48	76	10	-	-	NOUN
gra-48	76	11	cadherin	cadherin	NOUN
gra-48	76	12	in	in	ADP
gra-48	76	13	tumor	tumor	NOUN
gra-48	76	14	progression	progression	NOUN
gra-48	76	15	.	.	PUNCT
gra-48	77	1	authors	author	NOUN
gra-48	77	2	reported	report	VERB
gra-48	77	3	that	that	SCONJ
gra-48	77	4	decreased	decrease	VERB
gra-48	77	5	expression	expression	NOUN
gra-48	77	6	of	of	ADP
gra-48	77	7	e	e	NOUN
gra-48	77	8	-	-	NOUN
gra-48	77	9	cadherin	cadherin	NOUN
gra-48	77	10	correlated	correlate	VERB
gra-48	77	11	with	with	ADP
gra-48	77	12	poor	poor	ADJ
gra-48	77	13	prognosis	prognosis	NOUN
gra-48	77	14	(	(	PUNCT
gra-48	77	15	26,27,28	26,27,28	NUM
gra-48	77	16	)	)	PUNCT
gra-48	77	17	while	while	SCONJ
gra-48	77	18	unaltered	unaltered	ADJ
gra-48	77	19	ecadherin	ecadherin	NOUN
gra-48	77	20	level	level	NOUN
gra-48	77	21	has	have	AUX
gra-48	77	22	been	be	AUX
gra-48	77	23	found	find	VERB
gra-48	77	24	in	in	ADP
gra-48	77	25	in	in	ADP
gra-48	77	26	patients	patient	NOUN
gra-48	77	27	with	with	ADP
gra-48	77	28	inammatory	inammatory	ADJ
gra-48	77	29	bowel	bowel	NOUN
gra-48	77	30	disease	disease	NOUN
gra-48	77	31	(	(	PUNCT
gra-48	77	32	ibd	ibd	NOUN
gra-48	77	33	)	)	PUNCT
gra-48	77	34	or	or	CCONJ
gra-48	77	35	early	early	ADJ
gra-48	77	36	stage	stage	NOUN
gra-48	77	37	colorectal	colorectal	ADJ
gra-48	77	38	tumors	tumor	NOUN
gra-48	77	39	(	(	PUNCT
gra-48	77	40	29	29	NUM
gra-48	77	41	)	)	PUNCT
gra-48	77	42	.	.	PUNCT
gra-48	78	1	in	in	ADP
gra-48	78	2	this	this	DET
gra-48	78	3	study	study	NOUN
gra-48	78	4	,	,	PUNCT
gra-48	78	5	loss	loss	NOUN
gra-48	78	6	of	of	ADP
gra-48	78	7	e	e	NOUN
gra-48	78	8	-	-	NOUN
gra-48	78	9	cadherin	cadherin	NOUN
gra-48	78	10	was	be	AUX
gra-48	78	11	demonstrated	demonstrate	VERB
gra-48	78	12	to	to	PART
gra-48	78	13	be	be	AUX
gra-48	78	14	found	find	VERB
gra-48	78	15	more	more	ADV
gra-48	78	16	frequently	frequently	ADV
gra-48	78	17	in	in	ADP
gra-48	78	18	mucinous	mucinous	ADJ
gra-48	78	19	tumors	tumor	NOUN
gra-48	78	20	.	.	PUNCT
gra-48	79	1	we	we	PRON
gra-48	79	2	found	find	VERB
gra-48	79	3	that	that	SCONJ
gra-48	79	4	ecadherin	ecadherin	NOUN
gra-48	79	5	expression	expression	NOUN
gra-48	79	6	were	be	AUX
gra-48	79	7	similar	similar	ADJ
gra-48	79	8	to	to	ADP
gra-48	79	9	normal	normal	ADJ
gra-48	79	10	mucosa	mucosa	NOUN
gra-48	79	11	in	in	ADP
gra-48	79	12	majority	majority	NOUN
gra-48	79	13	of	of	ADP
gra-48	79	14	classic	classic	ADJ
gra-48	79	15	adenocarcinomas	adenocarcinoma	NOUN
gra-48	79	16	.	.	PUNCT
gra-48	80	1	the	the	DET
gra-48	80	2	ability	ability	NOUN
gra-48	80	3	of	of	ADP
gra-48	80	4	matrix	matrix	NOUN
gra-48	80	5	metalloproteinases	metalloproteinase	NOUN
gra-48	80	6	to	to	PART
gra-48	80	7	enhance	enhance	VERB
gra-48	80	8	tumor	tumor	NOUN
gra-48	80	9	cell	cell	NOUN
gra-48	80	10	invasion	invasion	NOUN
gra-48	80	11	has	have	AUX
gra-48	80	12	been	be	AUX
gra-48	80	13	thought	think	VERB
gra-48	80	14	to	to	PART
gra-48	80	15	be	be	AUX
gra-48	80	16	a	a	DET
gra-48	80	17	result	result	NOUN
gra-48	80	18	of	of	ADP
gra-48	80	19	the	the	DET
gra-48	80	20	degradation	degradation	NOUN
gra-48	80	21	of	of	ADP
gra-48	80	22	the	the	DET
gra-48	80	23	extracellular	extracellular	ADJ
gra-48	80	24	matrix	matrix	NOUN
gra-48	80	25	.	.	PUNCT
gra-48	81	1	authors	author	NOUN
gra-48	81	2	found	find	VERB
gra-48	81	3	that	that	SCONJ
gra-48	81	4	that	that	DET
gra-48	81	5	matrix	matrix	NOUN
gra-48	81	6	metalloproteinase	metalloproteinase	NOUN
gra-48	81	7	mediated	mediate	VERB
gra-48	81	8	induction	induction	NOUN
gra-48	81	9	of	of	ADP
gra-48	81	10	cellular	cellular	ADJ
gra-48	81	11	invasion	invasion	NOUN
gra-48	81	12	also	also	ADV
gra-48	81	13	can	can	AUX
gra-48	81	14	be	be	AUX
gra-48	81	15	independent	independent	ADJ
gra-48	81	16	of	of	ADP
gra-48	81	17	direct	direct	ADJ
gra-48	81	18	matrix	matrix	NOUN
gra-48	81	19	degradation	degradation	NOUN
gra-48	81	20	and	and	CCONJ
gra-48	81	21	,	,	PUNCT
gra-48	81	22	instead	instead	ADV
gra-48	81	23	,	,	PUNCT
gra-48	81	24	a	a	DET
gra-48	81	25	result	result	NOUN
gra-48	81	26	of	of	ADP
gra-48	81	27	the	the	DET
gra-48	81	28	release	release	NOUN
gra-48	81	29	of	of	ADP
gra-48	81	30	e	e	NOUN
gra-48	81	31	-	-	NOUN
gra-48	81	32	cadherin	cadherin	NOUN
gra-48	81	33	fragments	fragment	NOUN
gra-48	81	34	(	(	PUNCT
gra-48	81	35	30	30	NUM
gra-48	81	36	)	)	PUNCT
gra-48	81	37	.	.	PUNCT
gra-48	82	1	in	in	ADP
gra-48	82	2	addition	addition	NOUN
gra-48	82	3	,	,	PUNCT
gra-48	82	4	authors	author	NOUN
gra-48	82	5	found	find	VERB
gra-48	82	6	that	that	SCONJ
gra-48	82	7	the	the	DET
gra-48	82	8	increase	increase	NOUN
gra-48	82	9	in	in	ADP
gra-48	82	10	the	the	DET
gra-48	82	11	metastatic	metastatic	ADJ
gra-48	82	12	potential	potential	NOUN
gra-48	82	13	of	of	ADP
gra-48	82	14	tumour	tumour	NOUN
gra-48	82	15	cells	cell	NOUN
gra-48	82	16	is	be	AUX
gra-48	82	17	associated	associate	VERB
gra-48	82	18	with	with	ADP
gra-48	82	19	an	an	DET
gra-48	82	20	increased	increase	VERB
gra-48	82	21	expression	expression	NOUN
gra-48	82	22	of	of	ADP
gra-48	82	23	mmp-2	mmp-2	NUM
gra-48	82	24	and	and	CCONJ
gra-48	82	25	a	a	DET
gra-48	82	26	decreased	decrease	VERB
gra-48	82	27	expression	expression	NOUN
gra-48	82	28	of	of	ADP
gra-48	82	29	ecadherin(31	ecadherin(31	PROPN
gra-48	82	30	)	)	PUNCT
gra-48	82	31	.	.	PUNCT
gra-48	83	1	however	however	ADV
gra-48	83	2	we	we	PRON
gra-48	83	3	did	do	VERB
gra-48	83	4	not	not	PART
gra-48	83	5	nd	nd	ADV
gra-48	83	6	the	the	DET
gra-48	83	7	relation	relation	NOUN
gra-48	83	8	betwwen	betwwen	NOUN
gra-48	83	9	mmpand	mmpand	PROPN
gra-48	83	10	e	e	NOUN
gra-48	83	11	-	-	NOUN
gra-48	83	12	cadherin	cadherin	NOUN
gra-48	83	13	,	,	PUNCT
gra-48	83	14	in	in	ADP
gra-48	83	15	the	the	DET
gra-48	83	16	present	present	ADJ
gra-48	83	17	study	study	NOUN
gra-48	83	18	.	.	PUNCT
gra-48	84	1	we	we	PRON
gra-48	84	2	thougt	thougt	VERB
gra-48	84	3	that	that	SCONJ
gra-48	84	4	the	the	DET
gra-48	84	5	present	present	ADJ
gra-48	84	6	study	study	NOUN
gra-48	84	7	may	may	AUX
gra-48	84	8	indicates	indicate	VERB
gra-48	84	9	that	that	SCONJ
gra-48	84	10	the	the	DET
gra-48	84	11	extracellular	extracellular	ADJ
gra-48	84	12	matrix	matrix	NOUN
gra-48	84	13	transition	transition	NOUN
gra-48	84	14	(	(	PUNCT
gra-48	84	15	emt	emt	NOUN
gra-48	84	16	)	)	PUNCT
gra-48	84	17	process	process	NOUN
gra-48	84	18	may	may	AUX
gra-48	84	19	be	be	AUX
gra-48	84	20	different	different	ADJ
gra-48	84	21	in	in	ADP
gra-48	84	22	classic	classic	ADJ
gra-48	84	23	adenocarcinomas	adenocarcinoma	NOUN
gra-48	84	24	and	and	CCONJ
gra-48	84	25	mucinous	mucinous	ADJ
gra-48	84	26	tumors	tumor	NOUN
gra-48	84	27	.	.	PUNCT
gra-48	85	1	recent	recent	ADJ
gra-48	85	2	studies	study	NOUN
gra-48	85	3	described	describe	VERB
gra-48	85	4	wnt	wnt	NOUN
gra-48	85	5	signaling	signal	VERB
gra-48	85	6	pathway	pathway	NOUN
gra-48	85	7	is	be	AUX
gra-48	85	8	aberrantly	aberrantly	ADV
gra-48	85	9	upregulated	upregulate	VERB
gra-48	85	10	in	in	ADP
gra-48	85	11	both	both	CCONJ
gra-48	85	12	mss	mss	PROPN
gra-48	85	13	and	and	CCONJ
gra-48	85	14	msi	msi	PROPN
gra-48	85	15	colorectal	colorectal	ADJ
gra-48	85	16	cancers	cancer	NOUN
gra-48	85	17	.	.	PUNCT
gra-48	86	1	the	the	DET
gra-48	86	2	msi	msi	PROPN
gra-48	86	3	pathway	pathway	NOUN
gra-48	86	4	is	be	AUX
gra-48	86	5	often	often	ADV
gra-48	86	6	associated	associate	VERB
gra-48	86	7	with	with	ADP
gra-48	86	8	,	,	PUNCT
gra-48	86	9	mucinous	mucinous	ADJ
gra-48	86	10	morphology	morphology	NOUN
gra-48	86	11	,	,	PUNCT
gra-48	86	12	proximal	proximal	ADJ
gra-48	86	13	colon(32	colon(32	NOUN
gra-48	86	14	)	)	PUNCT
gra-48	86	15	.	.	PUNCT
gra-48	87	1	the	the	DET
gra-48	87	2	limitation	limitation	NOUN
gra-48	87	3	of	of	ADP
gra-48	87	4	our	our	PRON
gra-48	87	5	study	study	NOUN
gra-48	87	6	,	,	PUNCT
gra-48	87	7	study	study	VERB
gra-48	87	8	we	we	PRON
gra-48	87	9	did	do	AUX
gra-48	87	10	not	not	PART
gra-48	87	11	evaluate	evaluate	VERB
gra-48	87	12	molecular	molecular	ADJ
gra-48	87	13	msi	msi	NOUN
gra-48	87	14	status	status	NOUN
gra-48	87	15	and	and	CCONJ
gra-48	87	16	tumor	tumor	NOUN
gra-48	87	17	site	site	NOUN
gra-48	87	18	.	.	PUNCT
gra-48	88	1	in	in	ADP
gra-48	88	2	conclusion	conclusion	NOUN
gra-48	88	3	our	our	PRON
gra-48	88	4	nding	nding	NOUN
gra-48	88	5	prove	prove	VERB
gra-48	88	6	that	that	SCONJ
gra-48	88	7	mmp-2	mmp-2	NUM
gra-48	88	8	and	and	CCONJ
gra-48	88	9	loss	loss	NOUN
gra-48	88	10	of	of	ADP
gra-48	88	11	ecadherin	ecadherin	NOUN
gra-48	88	12	play	play	NOUN
gra-48	88	13	role	role	NOUN
gra-48	88	14	in	in	ADP
gra-48	88	15	colorectal	colorectal	ADJ
gra-48	88	16	carcinogenesis	carcinogenesis	NOUN
gra-48	88	17	however	however	ADV
gra-48	88	18	there	there	PRON
gra-48	88	19	is	be	VERB
gra-48	88	20	no	no	DET
gra-48	88	21	relation	relation	NOUN
gra-48	88	22	between	between	ADP
gra-48	88	23	the	the	DET
gra-48	88	24	mmp-2	mmp-2	NUM
gra-48	88	25	expression	expression	NOUN
gra-48	88	26	and	and	CCONJ
gra-48	88	27	loss	loss	NOUN
gra-48	88	28	of	of	ADP
gra-48	88	29	e	e	NOUN
gra-48	88	30	cadherin	cadherin	NOUN
gra-48	88	31	.	.	PUNCT
gra-48	89	1	it	it	PRON
gra-48	89	2	seems	seem	VERB
gra-48	89	3	that	that	SCONJ
gra-48	89	4	mmp-2	mmp-2	NUM
gra-48	89	5	expression	expression	NOUN
gra-48	89	6	was	be	AUX
gra-48	89	7	more	more	ADV
gra-48	89	8	related	related	ADJ
gra-48	89	9	with	with	ADP
gra-48	89	10	classic	classic	ADJ
gra-48	89	11	adenocarcinomas	adenocarcinoma	NOUN
gra-48	89	12	while	while	SCONJ
gra-48	89	13	loss	loss	NOUN
gra-48	89	14	of	of	ADP
gra-48	89	15	e	e	NOUN
gra-48	89	16	-	-	NOUN
gra-48	89	17	cadherin	cadherin	NOUN
gra-48	89	18	expression	expression	NOUN
gra-48	89	19	was	be	AUX
gra-48	89	20	more	more	ADV
gra-48	89	21	related	related	ADJ
gra-48	89	22	with	with	ADP
gra-48	89	23	mucinous	mucinous	ADJ
gra-48	89	24	adenocarc	adenocarc	NOUN
gra-48	89	25	volume-8	volume-8	NUM
gra-48	89	26	,	,	PUNCT
gra-48	89	27	issue-9	issue-9	NUM
gra-48	89	28	,	,	PUNCT
gra-48	89	29	september-2019	september-2019	ADJ
gra-48	89	30	•	•	NUM
gra-48	89	31	print	print	NOUN
gra-48	89	32	issn	issn	PROPN
gra-48	89	33	no	no	NOUN
gra-48	89	34	.	.	PROPN
gra-48	90	1	2277	2277	NUM
gra-48	90	2	8160	8160	NUM
gra-48	90	3	•	•	NOUN
gra-48	90	4	doi	doi	NOUN
gra-48	90	5	:	:	PUNCT
gra-48	90	6	10.36106	10.36106	NUM
gra-48	90	7	/	/	SYM
gra-48	90	8	gjra	gjra	NOUN
gra-48	90	9	x	x	SYM
gra-48	90	10	23gjra	23gjra	PROPN
gra-48	90	11	global	global	ADJ
gra-48	90	12	journal	journal	PROPN
gra-48	90	13	for	for	ADP
gra-48	90	14	research	research	NOUN
gra-48	90	15	analysis	analysis	NOUN
gra-48	90	16	inomas	inoma	NOUN
gra-48	90	17	.	.	PUNCT
gra-48	91	1	we	we	PRON
gra-48	91	2	thought	think	VERB
gra-48	91	3	that	that	SCONJ
gra-48	91	4	further	further	ADJ
gra-48	91	5	studies	study	NOUN
gra-48	91	6	needs	need	VERB
gra-48	91	7	to	to	ADP
gra-48	91	8	nd	nd	DET
gra-48	91	9	the	the	DET
gra-48	91	10	underlying	underlying	ADJ
gra-48	91	11	mechanism	mechanism	NOUN
gra-48	91	12	of	of	ADP
gra-48	91	13	extracellular	extracellular	ADJ
gra-48	91	14	matrix	matrix	NOUN
gra-48	91	15	transition	transition	NOUN
gra-48	91	16	in	in	ADP
gra-48	91	17	colorectal	colorectal	ADJ
gra-48	91	18	cancer	cancer	NOUN
gra-48	91	19	.	.	PUNCT
gra-48	92	1	figure	figure	VERB
gra-48	92	2	i	i	PRON
gra-48	92	3	:	:	PUNCT
gra-48	92	4	figure	figure	NOUN
gra-48	92	5	shows	show	VERB
gra-48	92	6	mmp-2	mmp-2	NUM
gra-48	92	7	expression	expression	NOUN
gra-48	92	8	in	in	ADP
gra-48	92	9	stromal	stromal	ADJ
gra-48	92	10	broblast	broblast	NOUN
gra-48	92	11	(	(	PUNCT
gra-48	92	12	mmp-2x100	mmp-2x100	PROPN
gra-48	92	13	)	)	PUNCT
gra-48	92	14	figureii	figureii	NOUN
gra-48	92	15	:	:	PUNCT
gra-48	92	16	figure	figure	NOUN
gra-48	92	17	shows	show	VERB
gra-48	92	18	grade	grade	NOUN
gra-48	92	19	3	3	NUM
gra-48	92	20	e	e	NOUN
gra-48	92	21	–	–	PUNCT
gra-48	92	22	cadherin	cadherin	NOUN
gra-48	92	23	expression	expression	NOUN
gra-48	92	24	(	(	PUNCT
gra-48	92	25	ecadherin	ecadherin	PROPN
gra-48	92	26	x40	x40	PROPN
gra-48	92	27	)	)	PUNCT
gra-48	92	28	figure	figure	NOUN
gra-48	92	29	iii	iii	NUM
gra-48	92	30	fıgure	fıgure	NOUN
gra-48	92	31	shows	show	VERB
gra-48	92	32	loss	loss	NOUN
gra-48	92	33	of	of	ADP
gra-48	92	34	membranous	membranous	ADJ
gra-48	92	35	expression	expression	NOUN
gra-48	92	36	in	in	ADP
gra-48	92	37	mucinous	mucinous	ADJ
gra-48	92	38	adenocarciomas	adenocarcioma	NOUN
gra-48	92	39	(	(	PUNCT
gra-48	92	40	ecadherin	ecadherin	NOUN
gra-48	92	41	x20	x20	NOUN
gra-48	92	42	)	)	PUNCT
gra-48	92	43	table	table	NOUN
gra-48	93	1	i	i	PRON
gra-48	93	2	:	:	PUNCT
gra-48	93	3	the	the	DET
gra-48	93	4	distrubution	distrubution	NOUN
gra-48	93	5	of	of	ADP
gra-48	93	6	mmp2	mmp2	ADJ
gra-48	93	7	staining	stain	VERB
gra-48	93	8	intensity	intensity	NOUN
gra-48	93	9	table	table	PROPN
gra-48	93	10	ii	ii	PROPN
gra-48	93	11	:	:	PUNCT
gra-48	93	12	the	the	DET
gra-48	93	13	distrubution	distrubution	NOUN
gra-48	93	14	of	of	ADP
gra-48	93	15	e	e	NOUN
gra-48	93	16	-	-	NOUN
gra-48	93	17	cadherin	cadherin	NOUN
gra-48	93	18	staining	stain	VERB
gra-48	93	19	references	reference	NOUN
gra-48	93	20	1bhandari	1bhandari	NUM
gra-48	93	21	a	a	PRON
gra-48	93	22	,	,	PUNCT
gra-48	93	23	woodhouse	woodhouse	PROPN
gra-48	93	24	m	m	PROPN
gra-48	93	25	,	,	PUNCT
gra-48	93	26	gupta	gupta	PROPN
gra-48	93	27	s.	s.	PROPN
gra-48	93	28	colorectal	colorectal	ADJ
gra-48	93	29	cancer	cancer	NOUN
gra-48	93	30	is	be	AUX
gra-48	93	31	a	a	DET
gra-48	93	32	leading	lead	VERB
gra-48	93	33	cause	cause	NOUN
gra-48	93	34	of	of	ADP
gra-48	93	35	cancer	cancer	NOUN
gra-48	93	36	incidence	incidence	NOUN
gra-48	93	37	and	and	CCONJ
gra-48	93	38	mortality	mortality	NOUN
gra-48	93	39	among	among	ADP
gra-48	93	40	adults	adult	NOUN
gra-48	93	41	younger	young	ADJ
gra-48	93	42	than	than	ADP
gra-48	93	43	50	50	NUM
gra-48	93	44	years	year	NOUN
gra-48	93	45	in	in	ADP
gra-48	93	46	the	the	DET
gra-48	93	47	usa	usa	PROPN
gra-48	93	48	:	:	PUNCT
gra-48	93	49	a	a	DET
gra-48	93	50	seer	seer	NOUN
gra-48	93	51	-	-	PUNCT
gra-48	93	52	based	base	VERB
gra-48	93	53	analysis	analysis	NOUN
gra-48	93	54	with	with	ADP
gra-48	93	55	comparison	comparison	NOUN
gra-48	93	56	to	to	ADP
gra-48	93	57	other	other	ADJ
gra-48	93	58	young	young	ADJ
gra-48	93	59	-	-	PUNCT
gra-48	93	60	onset	onset	VERB
gra-48	93	61	cancers	cancer	NOUN
gra-48	93	62	.	.	PUNCT
gra-48	94	1	j	j	PROPN
gra-48	94	2	investig	investig	NOUN
gra-48	94	3	med	med	PROPN
gra-48	94	4	.	.	PUNCT
gra-48	95	1	2017	2017	NUM
gra-48	95	2	feb;65(2):311	feb;65(2):311	NUM
gra-48	95	3	-	-	SYM
gra-48	95	4	315	315	NUM
gra-48	95	5	.	.	NOUN
gra-48	95	6	2	2	NUM
gra-48	95	7	gialeli	gialeli	NOUN
gra-48	95	8	c	c	NOUN
gra-48	95	9	,	,	PUNCT
gra-48	95	10	theocharis	theocharis	PROPN
gra-48	95	11	ad	ad	NOUN
gra-48	95	12	,	,	PUNCT
gra-48	95	13	karamanos	karamanos	PROPN
gra-48	95	14	nk	nk	PROPN
gra-48	95	15	.	.	PROPN
gra-48	95	16	roles	role	NOUN
gra-48	95	17	of	of	ADP
gra-48	95	18	matrix	matrix	NOUN
gra-48	95	19	metalloproteinases	metalloproteinase	NOUN
gra-48	95	20	in	in	ADP
gra-48	95	21	cancer	cancer	NOUN
gra-48	95	22	progression	progression	NOUN
gra-48	95	23	and	and	CCONJ
gra-48	95	24	their	their	PRON
gra-48	95	25	pharmacological	pharmacological	ADJ
gra-48	95	26	targeting	targeting	NOUN
gra-48	95	27	.	.	PUNCT
gra-48	96	1	febs	febs	PROPN
gra-48	96	2	j.	j.	PROPN
gra-48	96	3	2011	2011	NUM
gra-48	96	4	jan;278(1):16	jan;278(1):16	PROPN
gra-48	96	5	-	-	PUNCT
gra-48	96	6	27	27	NUM
gra-48	96	7	.	.	PUNCT
gra-48	96	8	3	3	NUM
gra-48	96	9	hua	hua	PROPN
gra-48	96	10	h.	h.	PROPN
gra-48	96	11	,	,	PUNCT
gra-48	96	12	li	li	PROPN
gra-48	96	13	m.	m.	PROPN
gra-48	96	14	,	,	PUNCT
gra-48	96	15	luo	luo	PROPN
gra-48	96	16	t.	t.	PROPN
gra-48	96	17	,	,	PUNCT
gra-48	96	18	yin	yin	PROPN
gra-48	96	19	y.	y.	PROPN
gra-48	96	20	,	,	PUNCT
gra-48	96	21	jiang	jiang	PROPN
gra-48	96	22	y.	y.	PROPN
gra-48	96	23	matrix	matrix	NOUN
gra-48	96	24	metalloproteinases	metalloproteinase	NOUN
gra-48	96	25	in	in	ADP
gra-48	96	26	tumorigenesis	tumorigenesis	NOUN
gra-48	96	27	:	:	PUNCT
gra-48	96	28	an	an	DET
gra-48	96	29	evolving	evolve	VERB
gra-48	96	30	paradigm	paradigm	NOUN
gra-48	96	31	.	.	PUNCT
gra-48	97	1	cell	cell	NOUN
gra-48	97	2	.	.	PUNCT
gra-48	98	1	mol	mol	PROPN
gra-48	98	2	.	.	PROPN
gra-48	99	1	life	life	PROPN
gra-48	99	2	sci	sci	PROPN
gra-48	99	3	.	.	PUNCT
gra-48	100	1	2011;68:3853–3868	2011;68:3853–3868	PROPN
gra-48	100	2	4salem	4salem	NUM
gra-48	100	3	n	n	CCONJ
gra-48	100	4	,	,	PUNCT
gra-48	100	5	kamal	kamal	PROPN
gra-48	100	6	i	i	PRON
gra-48	100	7	,	,	PUNCT
gra-48	100	8	al	al	PROPN
gra-48	100	9	-	-	PUNCT
gra-48	100	10	maghrabi	maghrabi	PROPN
gra-48	100	11	j	j	PROPN
gra-48	100	12	,	,	PUNCT
gra-48	100	13	abuzenadah	abuzenadah	PROPN
gra-48	100	14	a	a	DET
gra-48	100	15	,	,	PUNCT
gra-48	100	16	peer	peer	NOUN
gra-48	100	17	-	-	PUNCT
gra-48	100	18	zada	zada	PROPN
gra-48	100	19	aa	aa	PROPN
gra-48	100	20	,	,	PUNCT
gra-48	100	21	qari	qari	PROPN
gra-48	100	22	y	y	PROPN
gra-48	100	23	,	,	PUNCT
gra-48	100	24	alahwal	alahwal	PROPN
gra-48	100	25	m	m	PROPN
gra-48	100	26	,	,	PUNCT
gra-48	100	27	al	al	PROPN
gra-48	100	28	-	-	PUNCT
gra-48	100	29	qahtani	qahtani	PROPN
gra-48	100	30	m	m	PROPN
gra-48	100	31	,	,	PUNCT
gra-48	100	32	buhmeida	buhmeida	PROPN
gra-48	100	33	a.	a.	NOUN
gra-48	100	34	high	high	ADJ
gra-48	100	35	expression	expression	NOUN
gra-48	100	36	of	of	ADP
gra-48	100	37	matrix	matrix	NOUN
gra-48	100	38	metalloproteinases	metalloproteinase	NOUN
gra-48	100	39	:	:	PUNCT
gra-48	100	40	mmp-2	mmp-2	NUM
gra-48	100	41	and	and	CCONJ
gra-48	100	42	mmp-9	mmp-9	NOUN
gra-48	100	43	predicts	predict	NOUN
gra-48	100	44	poor	poor	ADJ
gra-48	100	45	survival	survival	NOUN
gra-48	100	46	outcome	outcome	NOUN
gra-48	100	47	in	in	ADP
gra-48	100	48	colorectal	colorectal	ADJ
gra-48	100	49	carcinoma	carcinoma	NOUN
gra-48	100	50	.	.	PUNCT
gra-48	101	1	future	future	ADJ
gra-48	101	2	oncol	oncol	ADJ
gra-48	101	3	.	.	PUNCT
gra-48	102	1	2016;12(3):323	2016;12(3):323	PROPN
gra-48	102	2	-	-	PUNCT
gra-48	102	3	331	331	NUM
gra-48	102	4	.	.	PUNCT
gra-48	103	1	5langenskiold	5langenskiold	NUM
gra-48	103	2	m.	m.	NOUN
gra-48	103	3	,	,	PUNCT
gra-48	103	4	holmdahl	holmdahl	PROPN
gra-48	103	5	l.	l.	PROPN
gra-48	103	6	,	,	PUNCT
gra-48	103	7	falk	falk	PROPN
gra-48	103	8	p.	p.	PROPN
gra-48	103	9	,	,	PUNCT
gra-48	103	10	ivarsson	ivarsson	PROPN
gra-48	103	11	m.l	m.l	PROPN
gra-48	103	12	.	.	PROPN
gra-48	103	13	increased	increase	VERB
gra-48	103	14	plasma	plasma	NOUN
gra-48	103	15	mmp2	mmp2	ADJ
gra-48	103	16	protein	protein	NOUN
gra-48	103	17	expression	expression	NOUN
gra-48	103	18	in	in	ADP
gra-48	103	19	lymph	lymph	NOUN
gra-48	103	20	node	node	NOUN
gra-48	103	21	-	-	PUNCT
gra-48	103	22	positive	positive	ADJ
gra-48	103	23	patients	patient	NOUN
gra-48	103	24	with	with	ADP
gra-48	103	25	colorectal	colorectal	ADJ
gra-48	103	26	cancer	cancer	NOUN
gra-48	103	27	.	.	PUNCT
gra-48	104	1	int	int	NOUN
gra-48	104	2	.	.	PUNCT
gra-48	105	1	j.	j.	PROPN
gra-48	105	2	colorectal	colorectal	PROPN
gra-48	105	3	dis	dis	PROPN
gra-48	105	4	.	.	PUNCT
gra-48	106	1	2005;20:245–252	2005;20:245–252	NUM
gra-48	106	2	6	6	NUM
gra-48	106	3	hong	hong	PROPN
gra-48	106	4	sw	sw	PROPN
gra-48	106	5	,	,	PUNCT
gra-48	106	6	kang	kang	PROPN
gra-48	106	7	yk	yk	PROPN
gra-48	106	8	,	,	PUNCT
gra-48	106	9	lee	lee	PROPN
gra-48	106	10	b	b	PROPN
gra-48	106	11	,	,	PUNCT
gra-48	106	12	lee	lee	PROPN
gra-48	106	13	wy	wy	PROPN
gra-48	106	14	,	,	PUNCT
gra-48	106	15	jang	jang	PROPN
gra-48	106	16	yg	yg	PROPN
gra-48	106	17	,	,	PUNCT
gra-48	106	18	paik	paik	PROPN
gra-48	106	19	iw	iw	PROPN
gra-48	106	20	,	,	PUNCT
gra-48	106	21	lee	lee	PROPN
gra-48	106	22	h	h	PROPN
gra-48	106	23	matrix	matrix	NOUN
gra-48	106	24	metalloproteinase-2	metalloproteinase-2	NUM
gra-48	106	25	and	and	CCONJ
gra-48	106	26	-7	-7	PUNCT
gra-48	106	27	expression	expression	NOUN
gra-48	106	28	in	in	ADP
gra-48	106	29	colorectal	colorectal	ADJ
gra-48	106	30	cancer	cancer	NOUN
gra-48	106	31	.	.	PUNCT
gra-48	107	1	j	j	PROPN
gra-48	107	2	korean	korean	ADJ
gra-48	107	3	soc	soc	PROPN
gra-48	107	4	coloproctol	coloproctol	PROPN
gra-48	107	5	.	.	PUNCT
gra-48	108	1	2011	2011	NUM
gra-48	108	2	;	;	PUNCT
gra-48	108	3	3:133	3:133	NUM
gra-48	108	4	-	-	SYM
gra-48	108	5	139	139	NUM
gra-48	108	6	.	.	X
gra-48	108	7	7	7	NUM
gra-48	108	8	canel	canel	NOUN
gra-48	108	9	m	m	NOUN
gra-48	108	10	,	,	PUNCT
gra-48	108	11	serrels	serrel	VERB
gra-48	108	12	a	a	PRON
gra-48	108	13	,	,	PUNCT
gra-48	108	14	frame	frame	PROPN
gra-48	108	15	mc	mc	PROPN
gra-48	108	16	,	,	PUNCT
gra-48	108	17	brunton	brunton	PROPN
gra-48	108	18	vg	vg	PROPN
gra-48	108	19	.	.	PUNCT
gra-48	109	1	e	e	X
gra-48	109	2	-	-	NOUN
gra-48	109	3	cadherin	cadherin	NOUN
gra-48	109	4	-	-	PUNCT
gra-48	109	5	integrin	integrin	NOUN
gra-48	109	6	crosstalk	crosstalk	NOUN
gra-48	109	7	in	in	ADP
gra-48	109	8	cancer	cancer	NOUN
gra-48	109	9	invasion	invasion	NOUN
gra-48	109	10	and	and	CCONJ
gra-48	109	11	metastasisj	metastasisj	PROPN
gra-48	109	12	cell	cell	PROPN
gra-48	109	13	sci	sci	PROPN
gra-48	109	14	.	.	PROPN
gra-48	109	15	2013	2013	NUM
gra-48	109	16	;	;	PUNCT
gra-48	109	17	126:393	126:393	NUM
gra-48	109	18	-	-	SYM
gra-48	109	19	401	401	NUM
gra-48	109	20	.	.	NOUN
gra-48	110	1	8	8	NUM
gra-48	110	2	clevers	clever	NOUN
gra-48	110	3	h	h	PROPN
gra-48	110	4	wnt	wnt	PROPN
gra-48	110	5	/	/	SYM
gra-48	110	6	beta	beta	NOUN
gra-48	110	7	-	-	PUNCT
gra-48	110	8	catenin	catenin	NOUN
gra-48	110	9	signaling	signal	VERB
gra-48	110	10	in	in	ADP
gra-48	110	11	development	development	NOUN
gra-48	110	12	and	and	CCONJ
gra-48	110	13	disease	disease	NOUN
gra-48	110	14	.	.	PUNCT
gra-48	111	1	cell	cell	NOUN
gra-48	111	2	2006	2006	NUM
gra-48	111	3	;	;	PUNCT
gra-48	111	4	127	127	NUM
gra-48	111	5	:	:	PUNCT
gra-48	111	6	469	469	NUM
gra-48	111	7	-	-	SYM
gra-48	111	8	480	480	NUM
gra-48	111	9	.	.	PUNCT
gra-48	112	1	9scholer	9scholer	NUM
gra-48	112	2	-	-	NOUN
gra-48	112	3	dahirel	dahirel	NOUN
gra-48	112	4	a	a	NOUN
gra-48	112	5	,	,	PUNCT
gra-48	112	6	schlabach	schlabach	PROPN
gra-48	112	7	mr	mr	PROPN
gra-48	112	8	,	,	PUNCT
gra-48	112	9	loo	loo	VERB
gra-48	112	10	a	a	PRON
gra-48	112	11	,	,	PUNCT
gra-48	112	12	et	et	PROPN
gra-48	112	13	al	al	PROPN
gra-48	112	14	.	.	PUNCT
gra-48	112	15	maintenance	maintenance	NOUN
gra-48	112	16	of	of	ADP
gra-48	112	17	adenomatous	adenomatous	ADJ
gra-48	112	18	polyposis	polyposis	NOUN
gra-48	112	19	coli	coli	NOUN
gra-48	112	20	(	(	PUNCT
gra-48	112	21	apc)-mutant	apc)-mutant	ADJ
gra-48	112	22	colorectal	colorectal	ADJ
gra-48	112	23	cancer	cancer	NOUN
gra-48	112	24	is	be	AUX
gra-48	112	25	dependent	dependent	ADJ
gra-48	112	26	on	on	ADP
gra-48	112	27	wnt	wnt	PROPN
gra-48	112	28	/	/	SYM
gra-48	112	29	betacatenin	betacatenin	NOUN
gra-48	112	30	signaling	signaling	NOUN
gra-48	112	31	.	.	PUNCT
gra-48	113	1	proc	proc	PROPN
gra-48	113	2	natl	natl	PROPN
gra-48	113	3	acad	acad	PROPN
gra-48	113	4	sci	sci	PROPN
gra-48	113	5	usa	usa	PROPN
gra-48	113	6	.	.	PROPN
gra-48	114	1	2011;108:17135–17140	2011;108:17135–17140	NUM
gra-48	114	2	10	10	NUM
gra-48	114	3	wu	wu	PROPN
gra-48	114	4	b	b	PROPN
gra-48	114	5	,	,	PUNCT
gra-48	114	6	crampton	crampton	PROPN
gra-48	114	7	sp	sp	PROPN
gra-48	114	8	,	,	PUNCT
gra-48	114	9	hughes	hughes	PROPN
gra-48	114	10	cc	cc	PROPN
gra-48	114	11	.	.	PROPN
gra-48	114	12	wnt	wnt	PROPN
gra-48	114	13	signaling	signal	VERB
gra-48	114	14	induces	induce	NOUN
gra-48	114	15	matrix	matrix	NOUN
gra-48	114	16	metalloproteinase	metalloproteinase	NOUN
gra-48	114	17	expression	expression	NOUN
gra-48	114	18	and	and	CCONJ
gra-48	114	19	regulates	regulate	VERB
gra-48	114	20	t	t	PROPN
gra-48	114	21	cell	cell	NOUN
gra-48	114	22	transmigration	transmigration	NOUN
gra-48	114	23	.	.	PUNCT
gra-48	115	1	immunity	immunity	NOUN
gra-48	115	2	.	.	PUNCT
gra-48	116	1	2007	2007	NUM
gra-48	116	2	;	;	PUNCT
gra-48	116	3	26	26	NUM
gra-48	116	4	:	:	SYM
gra-48	116	5	227239	227239	NUM
gra-48	116	6	.	.	PUNCT
gra-48	117	1	11tsanou	11tsanou	NUM
gra-48	117	2	e	e	NOUN
gra-48	117	3	,	,	PUNCT
gra-48	117	4	peschos	peschos	NOUN
gra-48	117	5	d	d	NOUN
gra-48	117	6	,	,	PUNCT
gra-48	117	7	batistatou	batistatou	VERB
gra-48	117	8	a	a	PRON
gra-48	117	9	,	,	PUNCT
gra-48	117	10	charalabopoulos	charalabopoulos	PROPN
gra-48	117	11	a	a	PROPN
gra-48	117	12	,	,	PUNCT
gra-48	118	1	charalabopoulos	charalabopoulos	PROPN
gra-48	118	2	k.	k.	PROPN
gra-48	118	3	the	the	DET
gra-48	118	4	e	e	PROPN
gra-48	118	5	-	-	NOUN
gra-48	118	6	cadherin	cadherin	NOUN
gra-48	118	7	adhesion	adhesion	NOUN
gra-48	118	8	molecule	molecule	NOUN
gra-48	118	9	and	and	CCONJ
gra-48	118	10	colorectal	colorectal	ADJ
gra-48	118	11	cancer	cancer	NOUN
gra-48	118	12	.	.	PUNCT
gra-48	119	1	a	a	DET
gra-48	119	2	global	global	ADJ
gra-48	119	3	literature	literature	NOUN
gra-48	119	4	approach	approach	NOUN
gra-48	119	5	.	.	PUNCT
gra-48	120	1	anticancer	anticancer	NOUN
gra-48	120	2	res	re	NOUN
gra-48	120	3	.	.	PROPN
gra-48	120	4	2008	2008	NUM
gra-48	121	1	nov	nov	PROPN
gra-48	121	2	-	-	NOUN
gra-48	121	3	dec;28(6a):3815	dec;28(6a):3815	PROPN
gra-48	121	4	-	-	PUNCT
gra-48	121	5	26	26	NUM
gra-48	121	6	.	.	PUNCT
gra-48	122	1	12christou	12christou	NUM
gra-48	122	2	n	n	CCONJ
gra-48	122	3	,	,	PUNCT
gra-48	122	4	perraud	perraud	VERB
gra-48	122	5	a	a	PRON
gra-48	122	6	,	,	PUNCT
gra-48	122	7	blondy	blondy	NOUN
gra-48	122	8	s	s	NOUN
gra-48	122	9	,	,	PUNCT
gra-48	122	10	jauberteau	jauberteau	PROPN
gra-48	122	11	mo	mo	PROPN
gra-48	122	12	,	,	PUNCT
gra-48	122	13	battu	battu	PROPN
gra-48	122	14	s	s	PROPN
gra-48	122	15	,	,	PUNCT
gra-48	122	16	mathonnet	mathonnet	NOUN
gra-48	122	17	m	m	PROPN
gra-48	122	18	ecadherin	ecadherin	NOUN
gra-48	122	19	:	:	PUNCT
gra-48	122	20	a	a	DET
gra-48	122	21	potential	potential	ADJ
gra-48	122	22	biomarker	biomarker	NOUN
gra-48	122	23	of	of	ADP
gra-48	122	24	colorectal	colorectal	ADJ
gra-48	122	25	cancer	cancer	NOUN
gra-48	122	26	prognosisoncol	prognosisoncol	PROPN
gra-48	122	27	lett	lett	PROPN
gra-48	122	28	.	.	PUNCT
gra-48	123	1	2017	2017	NUM
gra-48	123	2	jun;13(6):4571	jun;13(6):4571	PROPN
gra-48	123	3	-	-	PUNCT
gra-48	123	4	4576	4576	NUM
gra-48	123	5	.	.	PUNCT
gra-48	124	1	13	13	NUM
gra-48	124	2	fred	fred	PROPN
gra-48	124	3	t	t	PROPN
gra-48	124	4	bomsan	bomsan	NOUN
gra-48	124	5	,	,	PUNCT
gra-48	124	6	fatime	fatime	PROPN
gra-48	124	7	carneiro	carneiro	PROPN
gra-48	124	8	,	,	PUNCT
gra-48	124	9	ralph	ralph	PROPN
gra-48	124	10	h.	h.	PROPN
gra-48	124	11	hruban	hruban	PROPN
gra-48	124	12	,	,	PUNCT
gra-48	124	13	noil	noil	PROPN
gra-48	124	14	d.	d.	PROPN
gra-48	124	15	theise	theise	PROPN
gra-48	124	16	who	who	PRON
gra-48	124	17	classication	classication	NOUN
gra-48	124	18	of	of	ADP
gra-48	124	19	tumors	tumor	NOUN
gra-48	124	20	of	of	ADP
gra-48	124	21	the	the	DET
gra-48	124	22	digestive	digestive	ADJ
gra-48	124	23	system	system	NOUN
gra-48	124	24	iarc	iarc	NOUN
gra-48	124	25	:	:	PUNCT
gra-48	124	26	lyon	lyon	PROPN
gra-48	124	27	2010	2010	NUM
gra-48	124	28	14adachi	14adachi	NUM
gra-48	125	1	y.	y.	PROPN
gra-48	125	2	,	,	PUNCT
gra-48	125	3	yamamoto	yamamoto	PROPN
gra-48	125	4	h.	h.	PROPN
gra-48	125	5	,	,	PUNCT
gra-48	125	6	itoh	itoh	PROPN
gra-48	125	7	f.	f.	PROPN
gra-48	125	8	,	,	PUNCT
gra-48	125	9	hinoda	hinoda	ADP
gra-48	125	10	y.	y.	NOUN
gra-48	125	11	,	,	PUNCT
gra-48	125	12	okada	okada	PROPN
gra-48	125	13	y.	y.	PROPN
gra-48	125	14	,	,	PUNCT
gra-48	125	15	imai	imai	PROPN
gra-48	125	16	k.	k.	PROPN
gra-48	125	17	contribution	contribution	PROPN
gra-48	125	18	of	of	ADP
gra-48	125	19	matrilysin	matrilysin	NOUN
gra-48	125	20	(	(	PUNCT
gra-48	125	21	mmp-7	mmp-7	X
gra-48	125	22	)	)	PUNCT
gra-48	125	23	to	to	ADP
gra-48	125	24	the	the	DET
gra-48	125	25	metastatic	metastatic	ADJ
gra-48	125	26	pathway	pathway	NOUN
gra-48	125	27	of	of	ADP
gra-48	125	28	human	human	ADJ
gra-48	125	29	colorectal	colorectal	ADJ
gra-48	125	30	cancers	cancer	NOUN
gra-48	125	31	.	.	PUNCT
gra-48	126	1	gut	gut	VERB
gra-48	126	2	.	.	PUNCT
gra-48	127	1	1999;45:252–258	1999;45:252–258	NUM
gra-48	128	1	15dragutinovic	15dragutinovic	NUM
gra-48	128	2	v.v	v.v	PROPN
gra-48	128	3	.	.	PROPN
gra-48	128	4	,	,	PUNCT
gra-48	128	5	radonjic	radonjic	PROPN
gra-48	128	6	n.v	n.v	PROPN
gra-48	128	7	.	.	PROPN
gra-48	128	8	,	,	PUNCT
gra-48	128	9	petronijevic	petronijevic	PROPN
gra-48	128	10	n.d	n.d	PROPN
gra-48	128	11	.	.	PROPN
gra-48	128	12	,	,	PUNCT
gra-48	128	13	tatic	tatic	ADJ
gra-48	128	14	s.b	s.b	NOUN
gra-48	128	15	.	.	PROPN
gra-48	128	16	,	,	PUNCT
gra-48	128	17	dimitrijevic	dimitrijevic	PROPN
gra-48	128	18	i.b	i.b	PROPN
gra-48	128	19	.	.	PROPN
gra-48	128	20	,	,	PUNCT
gra-48	128	21	radovanovic	radovanovic	PROPN
gra-48	128	22	n.s	n.s	PROPN
gra-48	128	23	.	.	PROPN
gra-48	128	24	,	,	PUNCT
gra-48	128	25	krivokapic	krivokapic	PROPN
gra-48	128	26	z.v	z.v	PROPN
gra-48	128	27	.	.	PROPN
gra-48	128	28	matrix	matrix	NOUN
gra-48	128	29	metalloproteinase-2	metalloproteinase-2	PROPN
gra-48	128	30	(	(	PUNCT
gra-48	128	31	mmp-2	mmp-2	NUM
gra-48	128	32	)	)	PUNCT
gra-48	128	33	and	and	CCONJ
gra-48	128	34	-9	-9	INTJ
gra-48	128	35	(	(	PUNCT
gra-48	128	36	mmp-9	mmp-9	NUM
gra-48	128	37	)	)	PUNCT
gra-48	128	38	in	in	ADP
gra-48	128	39	preoperative	preoperative	ADJ
gra-48	128	40	serum	serum	NOUN
gra-48	128	41	as	as	ADP
gra-48	128	42	independent	independent	ADJ
gra-48	128	43	prognostic	prognostic	ADJ
gra-48	128	44	markers	marker	NOUN
gra-48	128	45	in	in	ADP
gra-48	128	46	patients	patient	NOUN
gra-48	128	47	with	with	ADP
gra-48	128	48	colorectal	colorectal	ADJ
gra-48	128	49	cancer	cancer	NOUN
gra-48	128	50	.	.	PUNCT
gra-48	129	1	mol	mol	PROPN
gra-48	129	2	.	.	PROPN
gra-48	129	3	cell	cell	NOUN
gra-48	129	4	.	.	PUNCT
gra-48	130	1	biochem	biochem	PROPN
gra-48	130	2	.	.	PUNCT
gra-48	131	1	2011;355:173–178	2011;355:173–178	X
gra-48	131	2	.	.	PUNCT
gra-48	132	1	16	16	NUM
gra-48	132	2	sunami	sunami	PROPN
gra-48	132	3	e.	e.	PROPN
gra-48	132	4	,	,	PUNCT
gra-48	132	5	tsuno	tsuno	PROPN
gra-48	132	6	n.	n.	PROPN
gra-48	132	7	,	,	PUNCT
gra-48	132	8	osada	osada	PROPN
gra-48	132	9	t.	t.	PROPN
gra-48	132	10	,	,	PUNCT
gra-48	132	11	saito	saito	PROPN
gra-48	132	12	s.	s.	PROPN
gra-48	132	13	,	,	PUNCT
gra-48	132	14	kitayama	kitayama	PROPN
gra-48	132	15	j.	j.	PROPN
gra-48	132	16	,	,	PUNCT
gra-48	132	17	tomozawa	tomozawa	PROPN
gra-48	132	18	s.	s.	PROPN
gra-48	132	19	,	,	PUNCT
gra-48	132	20	tsuruo	tsuruo	PROPN
gra-48	132	21	t.	t.	PROPN
gra-48	132	22	,	,	PUNCT
gra-48	132	23	shibata	shibata	PROPN
gra-48	132	24	y.	y.	PROPN
gra-48	132	25	,	,	PUNCT
gra-48	132	26	muto	muto	PROPN
gra-48	132	27	t.	t.	PROPN
gra-48	132	28	,	,	PUNCT
gra-48	132	29	nagawa	nagawa	PROPN
gra-48	132	30	h.	h.	PROPN
gra-48	132	31	mmp-1	mmp-1	ADV
gra-48	132	32	is	be	AUX
gra-48	132	33	a	a	DET
gra-48	132	34	prognostic	prognostic	ADJ
gra-48	132	35	marker	marker	NOUN
gra-48	132	36	for	for	ADP
gra-48	132	37	hematogenous	hematogenous	ADJ
gra-48	132	38	metastasis	metastasis	NOUN
gra-48	132	39	of	of	ADP
gra-48	132	40	colorectal	colorectal	ADJ
gra-48	132	41	cancer	cancer	NOUN
gra-48	132	42	.	.	PUNCT
gra-48	133	1	oncologist	oncologist	NOUN
gra-48	133	2	.	.	PUNCT
gra-48	134	1	2000;5:108–114	2000;5:108–114	NUM
gra-48	134	2	17	17	NUM
gra-48	134	3	waas	waas	NOUN
gra-48	134	4	et	et	PROPN
gra-48	134	5	,	,	PUNCT
gra-48	134	6	hendriks	hendriks	PROPN
gra-48	134	7	t	t	PROPN
gra-48	134	8	,	,	PUNCT
gra-48	134	9	lomme	lomme	PROPN
gra-48	134	10	rm	rm	PROPN
gra-48	134	11	,	,	PUNCT
gra-48	134	12	wobbes	wobbe	NOUN
gra-48	134	13	t.	t.	PROPN
gra-48	134	14	plasma	plasma	NOUN
gra-48	134	15	levels	level	NOUN
gra-48	134	16	of	of	ADP
gra-48	134	17	matrix	matrix	NOUN
gra-48	134	18	metalloproteinase-2	metalloproteinase-2	NUM
gra-48	134	19	and	and	CCONJ
gra-48	134	20	tissue	tissue	NOUN
gra-48	134	21	inhibitor	inhibitor	NOUN
gra-48	134	22	of	of	ADP
gra-48	134	23	metalloproteinase-1	metalloproteinase-1	NUM
gra-48	134	24	correlate	correlate	VERB
gra-48	134	25	with	with	ADP
gra-48	134	26	disease	disease	NOUN
gra-48	134	27	stage	stage	NOUN
gra-48	134	28	and	and	CCONJ
gra-48	134	29	survival	survival	NOUN
gra-48	134	30	in	in	ADP
gra-48	134	31	colorectal	colorectal	ADJ
gra-48	134	32	cancer	cancer	NOUN
gra-48	134	33	patients	patient	NOUN
gra-48	134	34	.	.	PUNCT
gra-48	135	1	dis	dis	PROPN
gra-48	135	2	colon	colon	NOUN
gra-48	135	3	rectum	rectum	NOUN
gra-48	135	4	2005;48:700–10	2005;48:700–10	NUM
gra-48	135	5	.	.	PUNCT
gra-48	136	1	18wong	18wong	PROPN
gra-48	137	1	jc	jc	PROPN
gra-48	137	2	,	,	PUNCT
gra-48	137	3	chan	chan	PROPN
gra-48	137	4	sk	sk	PROPN
gra-48	137	5	,	,	PUNCT
gra-48	137	6	schaeffer	schaeffer	PROPN
gra-48	137	7	df	df	PROPN
gra-48	137	8	,	,	PUNCT
gra-48	137	9	sagaert	sagaert	PROPN
gra-48	137	10	x	x	X
gra-48	137	11	,	,	PUNCT
gra-48	137	12	lim	lim	PROPN
gra-48	137	13	hj	hj	PROPN
gra-48	137	14	,	,	PUNCT
gra-48	137	15	kennecke	kennecke	PROPN
gra-48	137	16	h	h	PROPN
gra-48	137	17	,	,	PUNCT
gra-48	137	18	owen	owen	PROPN
gra-48	137	19	da	da	PROPN
gra-48	137	20	,	,	PUNCT
gra-48	137	21	suh	suh	PROPN
gra-48	137	22	kw	kw	PROPN
gra-48	137	23	,	,	PUNCT
gra-48	137	24	kim	kim	PROPN
gra-48	137	25	yb	yb	PROPN
gra-48	137	26	,	,	PUNCT
gra-48	137	27	tai	tai	VERB
gra-48	137	28	it	it	PRON
gra-48	137	29	.	.	PUNCT
gra-48	138	1	absence	absence	NOUN
gra-48	138	2	of	of	ADP
gra-48	138	3	mmp2	mmp2	ADJ
gra-48	138	4	expression	expression	NOUN
gra-48	138	5	correlates	correlate	VERB
gra-48	138	6	with	with	ADP
gra-48	138	7	poor	poor	ADJ
gra-48	138	8	clinical	clinical	ADJ
gra-48	138	9	outcomes	outcome	NOUN
gra-48	138	10	in	in	ADP
gra-48	138	11	rectal	rectal	ADJ
gra-48	138	12	cancer	cancer	NOUN
gra-48	138	13	,	,	PUNCT
gra-48	138	14	and	and	CCONJ
gra-48	138	15	is	be	AUX
gra-48	138	16	distinct	distinct	ADJ
gra-48	138	17	from	from	ADP
gra-48	138	18	mmp1	mmp1	NOUN
gra-48	138	19	-	-	PUNCT
gra-48	138	20	related	relate	VERB
gra-48	138	21	outcomes	outcome	NOUN
gra-48	138	22	in	in	ADP
gra-48	138	23	colon	colon	NOUN
gra-48	138	24	cancer	cancer	NOUN
gra-48	138	25	clin	clin	PROPN
gra-48	138	26	cancer	cancer	NOUN
gra-48	138	27	res	re	NOUN
gra-48	138	28	.	.	PUNCT
gra-48	139	1	2011	2011	NUM
gra-48	139	2	jun	jun	PROPN
gra-48	139	3	15;17(12):4167	15;17(12):4167	NUM
gra-48	139	4	-	-	SYM
gra-48	139	5	76	76	NUM
gra-48	139	6	19	19	NUM
gra-48	139	7	vihinen	vihinen	NOUN
gra-48	139	8	p	p	NOUN
gra-48	139	9	,	,	PUNCT
gra-48	139	10	kahari	kahari	PROPN
gra-48	139	11	vm	vm	PROPN
gra-48	139	12	.	.	PROPN
gra-48	139	13	matrix	matrix	NOUN
gra-48	139	14	metalloproteinases	metalloproteinase	NOUN
gra-48	139	15	in	in	ADP
gra-48	139	16	cancer	cancer	NOUN
gra-48	139	17	:	:	PUNCT
gra-48	139	18	prognostic	prognostic	ADJ
gra-48	139	19	markers	marker	NOUN
gra-48	139	20	and	and	CCONJ
gra-48	139	21	therapeutic	therapeutic	ADJ
gra-48	139	22	targets	target	NOUN
gra-48	139	23	.	.	PUNCT
gra-48	140	1	int	int	NOUN
gra-48	140	2	j	j	PROPN
gra-48	140	3	cancer	cancer	NOUN
gra-48	140	4	.	.	PUNCT
gra-48	141	1	2002;99:157–66	2002;99:157–66	X
gra-48	141	2	.	.	PROPN
gra-48	141	3	20	20	NUM
gra-48	141	4	groblewska	groblewska	PROPN
gra-48	141	5	m	m	PROPN
gra-48	141	6	,	,	PUNCT
gra-48	141	7	mroczko	mroczko	PROPN
gra-48	141	8	b	b	PROPN
gra-48	141	9	,	,	PUNCT
gra-48	141	10	gryko	gryko	ADJ
gra-48	141	11	m	m	PROPN
gra-48	141	12	,	,	PUNCT
gra-48	141	13	pryczynicz	pryczynicz	PROPN
gra-48	141	14	a	a	PRON
gra-48	141	15	,	,	PUNCT
gra-48	141	16	guzi	guzi	PROPN
gra-48	141	17	�	�	PROPN
gra-48	141	18	ska	ska	ADJ
gra-48	141	19	-	-	ADJ
gra-48	141	20	ustymowicz	ustymowicz	ADJ
gra-48	141	21	k	k	NOUN
gra-48	141	22	,	,	PUNCT
gra-48	141	23	k	k	PROPN
gra-48	141	24	�	�	PROPN
gra-48	141	25	dra	dra	PROPN
gra-48	141	26	b	b	PROPN
gra-48	141	27	,	,	PUNCT
gra-48	141	28	kemona	kemona	NOUN
gra-48	141	29	a	a	NOUN
gra-48	141	30	,	,	PUNCT
gra-48	141	31	szmitkowski	szmitkowski	PROPN
gra-48	141	32	m.	m.	NOUN
gra-48	141	33	serum	serum	NOUN
gra-48	141	34	levels	level	NOUN
gra-48	141	35	and	and	CCONJ
gra-48	141	36	tissue	tissue	NOUN
gra-48	141	37	expression	expression	NOUN
gra-48	141	38	of	of	ADP
gra-48	141	39	matr	matr	ADJ
gra-48	141	40	ix	ix	ADP
gra-48	141	41	metal	metal	NOUN
gra-48	141	42	lopro	lopro	NOUN
gra-48	141	43	te	te	AUX
gra-48	141	44	inase	inase	VERB
gra-48	141	45	2	2	NUM
gra-48	141	46	(	(	PUNCT
gra-48	141	47	mmp-2	mmp-2	NUM
gra-48	141	48	)	)	PUNCT
gra-48	141	49	and	and	CCONJ
gra-48	141	50	t	t	NOUN
gra-48	141	51	i	i	PRON
gra-48	141	52	ssue	ssue	NOUN
gra-48	141	53	inhib	inhib	VERB
gra-48	142	1	i	i	PRON
gra-48	142	2	tor	tor	VERB
gra-48	143	1	o	o	X
gra-48	143	2	f	f	NOUN
gra-48	143	3	metalloproteinases	metalloproteinase	VERB
gra-48	143	4	2	2	NUM
gra-48	143	5	(	(	PUNCT
gra-48	143	6	timp-2	timp-2	NOUN
gra-48	143	7	)	)	PUNCT
gra-48	143	8	in	in	ADP
gra-48	143	9	colorectal	colorectal	ADJ
gra-48	143	10	cancer	cancer	NOUN
gra-48	143	11	patients	patient	NOUN
gra-48	143	12	.	.	PUNCT
gra-48	144	1	tumour	tumour	PROPN
gra-48	144	2	biol	biol	PROPN
gra-48	144	3	.	.	PUNCT
gra-48	145	1	2014	2014	NUM
gra-48	145	2	;	;	PUNCT
gra-48	145	3	35(4):3793	35(4):3793	NUM
gra-48	145	4	-	-	SYM
gra-48	145	5	802	802	NUM
gra-48	145	6	.	.	PUNCT
gra-48	145	7	21paredes	21paredes	NUM
gra-48	146	1	j	j	PROPN
gra-48	146	2	,	,	PUNCT
gra-48	146	3	figueiredo	figueiredo	PROPN
gra-48	146	4	j	j	PROPN
gra-48	146	5	,	,	PUNCT
gra-48	146	6	albergaria	albergaria	PROPN
gra-48	146	7	a	a	PROPN
gra-48	146	8	,	,	PUNCT
gra-48	146	9	oliveira	oliveira	PROPN
gra-48	146	10	p	p	PROPN
gra-48	146	11	,	,	PUNCT
gra-48	146	12	carvalho	carvalho	PROPN
gra-48	146	13	j	j	PROPN
gra-48	146	14	,	,	PUNCT
gra-48	146	15	ribeiro	ribeiro	PROPN
gra-48	146	16	as	as	ADP
gra-48	146	17	,	,	PUNCT
gra-48	146	18	caldeira	caldeira	PROPN
gra-48	146	19	j	j	PROPN
gra-48	146	20	,	,	PUNCT
gra-48	146	21	costa	costa	PROPN
gra-48	146	22	am	be	AUX
gra-48	146	23	,	,	PUNCT
gra-48	146	24	simões	simões	PROPN
gra-48	146	25	-	-	PUNCT
gra-48	146	26	correia	correia	PROPN
gra-48	146	27	j	j	PROPN
gra-48	146	28	,	,	PUNCT
gra-48	146	29	oliveira	oliveira	PROPN
gra-48	146	30	mj	mj	PROPN
gra-48	146	31	,	,	PUNCT
gra-48	146	32	pinheiro	pinheiro	PROPN
gra-48	146	33	h	h	PROPN
gra-48	146	34	,	,	PUNCT
gra-48	146	35	pinho	pinho	PROPN
gra-48	146	36	ss	ss	PROPN
gra-48	146	37	,	,	PUNCT
gra-48	146	38	mateus	mateus	PROPN
gra-48	146	39	r	r	PROPN
gra-48	146	40	,	,	PUNCT
gra-48	146	41	reis	reis	NOUN
gra-48	146	42	ca	ca	PROPN
gra-48	146	43	,	,	PUNCT
gra-48	146	44	leite	leite	PROPN
gra-48	146	45	m	m	PROPN
gra-48	146	46	,	,	PUNCT
gra-48	146	47	fernandes	fernandes	PROPN
gra-48	146	48	ms	ms	PROPN
gra-48	146	49	,	,	PUNCT
gra-48	146	50	schmitt	schmitt	PROPN
gra-48	146	51	f	f	X
gra-48	146	52	,	,	PUNCT
gra-48	146	53	carneiro	carneiro	PROPN
gra-48	146	54	f	f	PROPN
gra-48	146	55	,	,	PUNCT
gra-48	146	56	figueiredo	figueiredo	PROPN
gra-48	146	57	c	c	PROPN
gra-48	146	58	,	,	PUNCT
gra-48	146	59	oliveira	oliveira	PROPN
gra-48	146	60	c	c	PROPN
gra-48	146	61	,	,	PUNCT
gra-48	146	62	seruca	seruca	PROPN
gra-48	146	63	r.	r.	PROPN
gra-48	146	64	epithelial	epithelial	PROPN
gra-48	146	65	eand	eand	PROPN
gra-48	146	66	p	p	X
gra-48	146	67	-	-	PUNCT
gra-48	146	68	cadherins	cadherin	VERB
gra-48	146	69	:	:	PUNCT
gra-48	146	70	role	role	NOUN
gra-48	146	71	and	and	CCONJ
gra-48	146	72	clinical	clinical	ADJ
gra-48	146	73	signicance	signicance	NOUN
gra-48	146	74	in	in	ADP
gra-48	146	75	cancer	cancer	NOUN
gra-48	146	76	.	.	PUNCT
gra-48	147	1	biochim	biochim	PROPN
gra-48	147	2	biophys	biophy	NOUN
gra-48	147	3	acta	acta	PROPN
gra-48	147	4	.	.	PUNCT
gra-48	148	1	2012;1826(2):297–311	2012;1826(2):297–311	NUM
gra-48	148	2	.	.	PUNCT
gra-48	149	1	22	22	NUM
gra-48	149	2	wijnhoven	wijnhoven	ADJ
gra-48	149	3	bp	bp	PROPN
gra-48	149	4	,	,	PUNCT
gra-48	149	5	dinjens	dinjen	VERB
gra-48	149	6	wn	wn	NOUN
gra-48	149	7	and	and	CCONJ
gra-48	149	8	pignatelli	pignatelli	NOUN
gra-48	149	9	m	m	PROPN
gra-48	149	10	:	:	PUNCT
gra-48	150	1	e	e	X
gra-48	150	2	-	-	NOUN
gra-48	150	3	cadherin	cadherin	NOUN
gra-48	150	4	-	-	PUNCT
gra-48	150	5	catenin	catenin	NOUN
gra-48	150	6	cell	cell	NOUN
gra-48	150	7	-	-	PUNCT
gra-48	150	8	cell	cell	NOUN
gra-48	150	9	adhesion	adhesion	NOUN
gra-48	150	10	complex	complex	ADJ
gra-48	150	11	and	and	CCONJ
gra-48	150	12	human	human	ADJ
gra-48	150	13	cancer	cancer	NOUN
gra-48	150	14	.	.	PUNCT
gra-48	151	1	br	br	PROPN
gra-48	151	2	j	j	PROPN
gra-48	151	3	surg	surg	PROPN
gra-48	151	4	2000	2000	NUM
gra-48	151	5	;	;	PUNCT
gra-48	151	6	87	87	NUM
gra-48	151	7	:	:	SYM
gra-48	151	8	992–1005	992–1005	NUM
gra-48	151	9	.	.	X
gra-48	151	10	23	23	NUM
gra-48	152	1	chao	chao	PROPN
gra-48	152	2	yl	yl	NOUN
gra-48	152	3	,	,	PUNCT
gra-48	152	4	shepard	shepard	NOUN
gra-48	152	5	cr	cr	PROPN
gra-48	152	6	and	and	CCONJ
gra-48	152	7	wells	wells	PROPN
gra-48	152	8	a	a	DET
gra-48	152	9	:	:	PUNCT
gra-48	152	10	breast	breast	NOUN
gra-48	152	11	carcinoma	carcinoma	NOUN
gra-48	152	12	cells	cell	NOUN
gra-48	152	13	re	re	VERB
gra-48	152	14	-	-	NOUN
gra-48	152	15	express	express	ADJ
gra-48	152	16	ecadherin	ecadherin	NOUN
gra-48	152	17	during	during	ADP
gra-48	152	18	mesenchymal	mesenchymal	NOUN
gra-48	152	19	to	to	ADP
gra-48	152	20	epithelial	epithelial	ADJ
gra-48	152	21	reverting	revert	VERB
gra-48	152	22	transition	transition	NOUN
gra-48	152	23	.	.	PUNCT
gra-48	153	1	mol	mol	ADP
gra-48	153	2	cancer	cancer	NOUN
gra-48	153	3	2010	2010	NUM
gra-48	153	4	;	;	PUNCT
gra-48	153	5	179	179	NUM
gra-48	153	6	,	,	PUNCT
gra-48	153	7	.	.	PUNCT
gra-48	154	1	24	24	NUM
gra-48	154	2	bae	bae	PROPN
gra-48	154	3	k	k	PROPN
gra-48	154	4	-	-	PROPN
gra-48	154	5	m	m	PROPN
gra-48	154	6	,	,	PUNCT
gra-48	154	7	parker	parker	PROPN
gra-48	154	8	nn	nn	PROPN
gra-48	154	9	,	,	PUNCT
gra-48	154	10	dai	dai	PROPN
gra-48	154	11	y	y	PROPN
gra-48	154	12	,	,	PUNCT
gra-48	154	13	vieweg	vieweg	VERB
gra-48	154	14	j	j	PROPN
gra-48	154	15	and	and	CCONJ
gra-48	154	16	siemann	siemann	PROPN
gra-48	154	17	dw	dw	PROPN
gra-48	154	18	:	:	PUNCT
gra-48	154	19	e	e	NOUN
gra-48	154	20	-	-	NOUN
gra-48	154	21	cadherin	cadherin	NOUN
gra-48	154	22	plasticity	plasticity	NOUN
gra-48	154	23	in	in	ADP
gra-48	154	24	prostate	prostate	NOUN
gra-48	154	25	cancer	cancer	NOUN
gra-48	154	26	stem	stem	NOUN
gra-48	154	27	cell	cell	NOUN
gra-48	154	28	invasion	invasion	NOUN
gra-48	154	29	.	.	PUNCT
gra-48	155	1	am	be	AUX
gra-48	155	2	j	j	PROPN
gra-48	155	3	cancer	cancer	NOUN
gra-48	155	4	res	re	NOUN
gra-48	155	5	2011	2011	NUM
gra-48	155	6	;	;	PUNCT
gra-48	155	7	1	1	NUM
gra-48	155	8	:	:	PUNCT
gra-48	155	9	71–84	71–84	NOUN
gra-48	155	10	.	.	PUNCT
gra-48	156	1	25	25	NUM
gra-48	156	2	he	he	PRON
gra-48	156	3	,	,	PUNCT
gra-48	156	4	x.	x.	PROPN
gra-48	156	5	;	;	PUNCT
gra-48	156	6	chen	chen	PROPN
gra-48	156	7	,	,	PUNCT
gra-48	156	8	z.	z.	PROPN
gra-48	156	9	;	;	PUNCT
gra-48	156	10	jia	jia	PROPN
gra-48	156	11	,	,	PUNCT
gra-48	156	12	m.	m.	NOUN
gra-48	156	13	;	;	PUNCT
gra-48	156	14	zhao	zhao	PROPN
gra-48	156	15	,	,	PUNCT
gra-48	156	16	x.	x.	NOUN
gra-48	156	17	downregulated	downregulate	VERB
gra-48	156	18	e	e	NOUN
gra-48	156	19	-	-	NOUN
gra-48	156	20	cadherin	cadherin	NOUN
gra-48	156	21	expression	expression	NOUN
gra-48	156	22	indicates	indicate	VERB
gra-48	156	23	worse	bad	ADJ
gra-48	156	24	prognosis	prognosis	NOUN
gra-48	156	25	in	in	ADP
gra-48	156	26	asian	asian	ADJ
gra-48	156	27	patients	patient	NOUN
gra-48	156	28	with	with	ADP
gra-48	156	29	colorectal	colorectal	ADJ
gra-48	156	30	cancer	cancer	NOUN
gra-48	156	31	:	:	PUNCT
gra-48	156	32	evidence	evidence	NOUN
gra-48	156	33	from	from	ADP
gra-48	156	34	meta	meta	ADJ
gra-48	156	35	-	-	PUNCT
gra-48	156	36	analysis	analysis	NOUN
gra-48	156	37	.	.	PUNCT
gra-48	157	1	plos	plos	PROPN
gra-48	157	2	one	one	NUM
gra-48	157	3	2013	2013	NUM
gra-48	157	4	,	,	PUNCT
gra-48	157	5	8	8	NUM
gra-48	157	6	,	,	PUNCT
gra-48	157	7	e70858	e70858	NOUN
gra-48	157	8	26	26	NUM
gra-48	157	9	karamitopoulou	karamitopoulou	NOUN
gra-48	157	10	,	,	PUNCT
gra-48	157	11	e.	e.	PROPN
gra-48	157	12	;	;	PUNCT
gra-48	157	13	zlobec	zlobec	PROPN
gra-48	157	14	,	,	PUNCT
gra-48	157	15	i.	i.	PROPN
gra-48	157	16	;	;	PUNCT
gra-48	157	17	patsouris	patsouris	PROPN
gra-48	157	18	,	,	PUNCT
gra-48	157	19	e.	e.	PROPN
gra-48	157	20	;	;	PUNCT
gra-48	157	21	peros	peros	PROPN
gra-48	157	22	,	,	PUNCT
gra-48	157	23	g.	g.	PROPN
gra-48	157	24	;	;	PUNCT
gra-48	157	25	lugli	lugli	NOUN
gra-48	157	26	,	,	PUNCT
gra-48	157	27	a.	a.	NOUN
gra-48	157	28	loss	loss	NOUN
gra-48	157	29	of	of	ADP
gra-48	157	30	ecadherin	ecadherin	NOUN
gra-48	157	31	independently	independently	ADV
gra-48	157	32	predicts	predict	VERB
gra-48	157	33	the	the	DET
gra-48	157	34	lymph	lymph	NOUN
gra-48	157	35	node	node	ADJ
gra-48	157	36	status	status	NOUN
gra-48	157	37	in	in	ADP
gra-48	157	38	colorectal	colorectal	ADJ
gra-48	157	39	cancer	cancer	NOUN
gra-48	157	40	.	.	PUNCT
gra-48	158	1	pathology	pathology	NOUN
gra-48	158	2	2011	2011	NUM
gra-48	158	3	;	;	PUNCT
gra-48	158	4	43	43	NUM
gra-48	158	5	,	,	PUNCT
gra-48	158	6	133–137	133–137	NUM
gra-48	158	7	.	.	PUNCT
gra-48	159	1	27	27	NUM
gra-48	159	2	tóth	tóth	NOUN
gra-48	159	3	,	,	PUNCT
gra-48	159	4	l.	l.	PROPN
gra-48	159	5	;	;	PUNCT
gra-48	159	6	andrás	andrás	PROPN
gra-48	159	7	,	,	PUNCT
gra-48	159	8	c.	c.	PROPN
gra-48	159	9	;	;	PUNCT
gra-48	159	10	molnár	molnár	PROPN
gra-48	159	11	,	,	PUNCT
gra-48	159	12	c.	c.	PROPN
gra-48	159	13	;	;	PUNCT
gra-48	159	14	tanyi	tanyi	PROPN
gra-48	159	15	,	,	PUNCT
gra-48	159	16	m.	m.	NOUN
gra-48	159	17	;	;	PUNCT
gra-48	159	18	csiki	csiki	PROPN
gra-48	159	19	,	,	PUNCT
gra-48	159	20	z.	z.	PROPN
gra-48	159	21	;	;	PUNCT
gra-48	159	22	molnár	molnár	PROPN
gra-48	159	23	,	,	PUNCT
gra-48	159	24	p.	p.	NOUN
gra-48	159	25	;	;	PUNCT
gra-48	159	26	szántó	szántó	PROPN
gra-48	159	27	,	,	PUNCT
gra-48	159	28	j.	j.	PROPN
gra-48	159	29	investigation	investigation	NOUN
gra-48	159	30	of	of	ADP
gra-48	159	31	_	_	NOUN
gra-48	159	32	-catenin	-catenin	ADJ
gra-48	159	33	and	and	CCONJ
gra-48	159	34	e	e	NOUN
gra-48	159	35	-	-	NOUN
gra-48	159	36	cadherin	cadherin	NOUN
gra-48	159	37	expression	expression	NOUN
gra-48	159	38	in	in	ADP
gra-48	159	39	dukes	duke	NOUN
gra-48	159	40	b2	b2	NOUN
gra-48	159	41	stage	stage	NOUN
gra-48	159	42	colorectal	colorectal	ADJ
gra-48	159	43	cancer	cancer	NOUN
gra-48	159	44	with	with	ADP
gra-48	159	45	tissue	tissue	NOUN
gra-48	159	46	microarray	microarray	NOUN
gra-48	159	47	method	method	NOUN
gra-48	159	48	.	.	PUNCT
gra-48	159	49	is	be	AUX
gra-48	159	50	it	it	PRON
gra-48	159	51	a	a	DET
gra-48	159	52	marker	marker	NOUN
gra-48	159	53	of	of	ADP
gra-48	159	54	metastatic	metastatic	ADJ
gra-48	159	55	potential	potential	NOUN
gra-48	159	56	in	in	ADP
gra-48	159	57	rectal	rectal	ADJ
gra-48	159	58	cancer	cancer	NOUN
gra-48	159	59	?	?	PUNCT
gra-48	160	1	pathol	pathol	NOUN
gra-48	160	2	.	.	PUNCT
gra-48	161	1	oncol	oncol	ADJ
gra-48	161	2	.	.	PUNCT
gra-48	162	1	res	re	NOUN
gra-48	162	2	.	.	PUNCT
gra-48	163	1	por	por	PROPN
gra-48	163	2	2012	2012	NUM
gra-48	163	3	;	;	PUNCT
gra-48	163	4	18	18	NUM
gra-48	163	5	,	,	PUNCT
gra-48	163	6	429–437	429–437	NUM
gra-48	163	7	.	.	PUNCT
gra-48	163	8	28	28	NUM
gra-48	163	9	khoursheed	khoursheed	NOUN
gra-48	163	10	,	,	PUNCT
gra-48	163	11	m.a	m.a	PROPN
gra-48	163	12	.	.	PROPN
gra-48	163	13	;	;	PUNCT
gra-48	163	14	mathew	mathew	PROPN
gra-48	163	15	,	,	PUNCT
gra-48	163	16	t.c	t.c	PROPN
gra-48	163	17	.	.	PROPN
gra-48	163	18	;	;	PUNCT
gra-48	164	1	makar	makar	PROPN
gra-48	164	2	,	,	PUNCT
gra-48	164	3	r.r	r.r	PROPN
gra-48	164	4	.	.	PROPN
gra-48	164	5	;	;	PUNCT
gra-48	164	6	louis	louis	PROPN
gra-48	164	7	,	,	PUNCT
gra-48	164	8	s.	s.	PROPN
gra-48	164	9	;	;	PUNCT
gra-48	164	10	asfar	asfar	ADV
gra-48	164	11	,	,	PUNCT
gra-48	164	12	s.k	s.k	PROPN
gra-48	164	13	.	.	PROPN
gra-48	164	14	;	;	PUNCT
gra-48	164	15	al	al	PROPN
gra-48	164	16	-	-	PUNCT
gra-48	164	17	sayer	sayer	PROPN
gra-48	164	18	,	,	PUNCT
gra-48	164	19	h.m	h.m	PROPN
gra-48	164	20	.	.	PROPN
gra-48	164	21	;	;	PUNCT
gra-48	164	22	dashti	dashti	NOUN
gra-48	164	23	,	,	PUNCT
gra-48	164	24	h.m	h.m	PROPN
gra-48	164	25	.	.	PROPN
gra-48	164	26	;	;	PUNCT
gra-48	165	1	al	al	PROPN
gra-48	165	2	-	-	PUNCT
gra-48	165	3	bader	bader	PROPN
gra-48	165	4	,	,	PUNCT
gra-48	165	5	a.	a.	NOUN
gra-48	165	6	expression	expression	NOUN
gra-48	165	7	of	of	ADP
gra-48	165	8	e	e	NOUN
gra-48	165	9	-	-	NOUN
gra-48	165	10	cadherin	cadherin	NOUN
gra-48	165	11	in	in	ADP
gra-48	165	12	human	human	ADJ
gra-48	165	13	colorectal	colorectal	ADJ
gra-48	165	14	cancer	cancer	NOUN
gra-48	165	15	.	.	PUNCT
gra-48	166	1	surg	surg	PROPN
gra-48	166	2	.	.	PUNCT
gra-48	167	1	j.	j.	PROPN
gra-48	167	2	r.	r.	PROPN
gra-48	167	3	coll	coll	PROPN
gra-48	167	4	.	.	PUNCT
gra-48	168	1	surg	surg	PROPN
gra-48	168	2	.	.	PUNCT
gra-48	169	1	edinb	edinb	PROPN
gra-48	169	2	.	.	PUNCT
gra-48	170	1	irel	irel	NOUN
gra-48	170	2	.	.	PUNCT
gra-48	171	1	2003	2003	NUM
gra-48	171	2	;	;	PUNCT
gra-48	171	3	1	1	NUM
gra-48	171	4	,	,	PUNCT
gra-48	171	5	86–91	86–91	NUM
gra-48	171	6	29	29	NUM
gra-48	171	7	weiss	weiss	NOUN
gra-48	171	8	,	,	PUNCT
gra-48	171	9	j.v	j.v	PROPN
gra-48	171	10	.	.	PROPN
gra-48	171	11	;	;	PUNCT
gra-48	171	12	klein	klein	PROPN
gra-48	171	13	-	-	PUNCT
gra-48	171	14	scory	scory	PROPN
gra-48	171	15	,	,	PUNCT
gra-48	171	16	s.	s.	PROPN
gra-48	171	17	;	;	PUNCT
gra-48	171	18	kübler	kübler	PROPN
gra-48	171	19	,	,	PUNCT
gra-48	171	20	s.	s.	PROPN
gra-48	171	21	;	;	PUNCT
gra-48	171	22	reinacher	reinacher	NOUN
gra-48	171	23	-	-	PUNCT
gra-48	171	24	schick	schick	NOUN
gra-48	171	25	,	,	PUNCT
gra-48	171	26	a.	a.	NOUN
gra-48	171	27	;	;	PUNCT
gra-48	171	28	stricker	stricker	PROPN
gra-48	171	29	,	,	PUNCT
gra-48	171	30	i.	i.	PROPN
gra-48	171	31	;	;	PUNCT
gra-48	171	32	schmiegel	schmiegel	PROPN
gra-48	171	33	,	,	PUNCT
gra-48	171	34	w.	w.	PROPN
gra-48	171	35	;	;	PUNCT
gra-48	171	36	schwarte	schwarte	NOUN
gra-48	171	37	-	-	PUNCT
gra-48	171	38	waldho	waldho	ADJ
gra-48	171	39	,	,	PUNCT
gra-48	171	40	i.soluble	i.soluble	ADJ
gra-48	171	41	e	e	NOUN
gra-48	171	42	-	-	NOUN
gra-48	171	43	cadherin	cadherin	NOUN
gra-48	171	44	as	as	ADP
gra-48	171	45	a	a	DET
gra-48	171	46	serum	serum	NOUN
gra-48	171	47	biomarker	biomarker	NOUN
gra-48	171	48	candidate	candidate	NOUN
gra-48	171	49	:	:	PUNCT
gra-48	171	50	elevated	elevated	ADJ
gra-48	171	51	levels	level	NOUN
gra-48	171	52	in	in	ADP
gra-48	171	53	patients	patient	NOUN
gra-48	171	54	with	with	ADP
gra-48	171	55	late	late	ADJ
gra-48	171	56	-	-	PUNCT
gra-48	171	57	stage	stage	NOUN
gra-48	171	58	colorectal	colorectal	ADJ
gra-48	171	59	carcinoma	carcinoma	NOUN
gra-48	171	60	and	and	CCONJ
gra-48	171	61	fap	fap	NOUN
gra-48	171	62	.	.	PUNCT
gra-48	172	1	int	int	NOUN
gra-48	172	2	.	.	PUNCT
gra-48	173	1	j.	j.	PROPN
gra-48	173	2	cancer	cancer	PROPN
gra-48	173	3	2011	2011	NUM
gra-48	173	4	;	;	PUNCT
gra-48	173	5	128	128	NUM
gra-48	173	6	,	,	PUNCT
gra-48	173	7	1384–1392	1384–1392	NUM
gra-48	173	8	30	30	NUM
gra-48	173	9	noë	noë	PROPN
gra-48	173	10	v	v	NOUN
gra-48	173	11	,	,	PUNCT
gra-48	173	12	fingleton	fingleton	PROPN
gra-48	173	13	b	b	PROPN
gra-48	173	14	,	,	PUNCT
gra-48	173	15	jacobs	jacobs	PROPN
gra-48	173	16	k	k	PROPN
gra-48	173	17	,	,	PUNCT
gra-48	173	18	crawford	crawford	PROPN
gra-48	173	19	hc	hc	PROPN
gra-48	173	20	,	,	PUNCT
gra-48	173	21	vermeulen	vermeulen	PROPN
gra-48	173	22	s	s	PROPN
gra-48	173	23	,	,	PUNCT
gra-48	173	24	steelant	steelant	ADJ
gra-48	173	25	w	w	PROPN
gra-48	173	26	,	,	PUNCT
gra-48	173	27	bruyneel	bruyneel	NOUN
gra-48	173	28	e	e	NOUN
gra-48	173	29	,	,	PUNCT
gra-48	173	30	matrisian	matrisian	PROPN
gra-48	173	31	lm	lm	PROPN
gra-48	173	32	,	,	PUNCT
gra-48	173	33	mareel	mareel	NOUN
gra-48	173	34	m.	m.	NOUN
gra-48	173	35	release	release	NOUN
gra-48	173	36	of	of	ADP
gra-48	173	37	an	an	DET
gra-48	173	38	invasion	invasion	NOUN
gra-48	173	39	promoter	promoter	NOUN
gra-48	173	40	e	e	NOUN
gra-48	173	41	-	-	NOUN
gra-48	173	42	cadherin	cadherin	NOUN
gra-48	173	43	fragment	fragment	NOUN
gra-48	173	44	by	by	ADP
gra-48	173	45	matrilysin	matrilysin	NOUN
gra-48	173	46	and	and	CCONJ
gra-48	173	47	stromelysin-1	stromelysin-1	PROPN
gra-48	173	48	.	.	PUNCT
gra-48	174	1	j	j	PROPN
gra-48	174	2	cell	cell	PROPN
gra-48	174	3	sci	sci	PROPN
gra-48	174	4	.	.	PROPN
gra-48	175	1	2001;j14(pt	2001;j14(pt	PROPN
gra-48	175	2	1):111	1):111	NUM
gra-48	175	3	-	-	SYM
gra-48	175	4	118	118	NUM
gra-48	175	5	.	.	PUNCT
gra-48	176	1	31nowak	31nowak	NUM
gra-48	176	2	m	m	NOUN
gra-48	176	3	,	,	PUNCT
gra-48	176	4	madej	madej	PROPN
gra-48	176	5	ja	ja	PROPN
gra-48	176	6	,	,	PUNCT
gra-48	176	7	pula	pula	PROPN
gra-48	176	8	b	b	PROPN
gra-48	176	9	,	,	PUNCT
gra-48	176	10	dziegiel	dziegiel	PROPN
gra-48	176	11	p	p	NOUN
gra-48	176	12	,	,	PUNCT
gra-48	176	13	ciaputa	ciaputa	ADJ
gra-48	176	14	r.expression	r.expression	NOUN
gra-48	176	15	of	of	ADP
gra-48	176	16	matrix	matrix	NOUN
gra-48	176	17	metalloproteinase	metalloproteinase	NOUN
gra-48	176	18	2	2	NUM
gra-48	176	19	(	(	PUNCT
gra-48	176	20	mmp-2	mmp-2	NUM
gra-48	176	21	)	)	PUNCT
gra-48	176	22	,	,	PUNCT
gra-48	176	23	e	e	NOUN
gra-48	176	24	-	-	NOUN
gra-48	176	25	cadherin	cadherin	NOUN
gra-48	176	26	and	and	CCONJ
gra-48	176	27	ki-67	ki-67	ADJ
gra-48	176	28	in	in	ADP
gra-48	176	29	metastatic	metastatic	ADJ
gra-48	176	30	and	and	CCONJ
gra-48	176	31	nonmetastatic	nonmetastatic	ADJ
gra-48	176	32	canine	canine	NOUN
gra-48	176	33	mammary	mammary	ADJ
gra-48	176	34	carcinomas	carcinoma	NOUN
gra-48	176	35	.	.	PUNCT
gra-48	177	1	ir	ir	PROPN
gra-48	177	2	vet	vet	NOUN
gra-48	177	3	j.	j.	PROPN
gra-48	177	4	2016	2016	NUM
gra-48	177	5	aug	aug	PROPN
gra-48	177	6	2;69:9	2;69:9	NUM
gra-48	177	7	.	.	PUNCT
gra-48	178	1	32cong	32cong	NUM
gra-48	179	1	luo	luo	PROPN
gra-48	179	2	,	,	PUNCT
gra-48	179	3	shuyi	shuyi	PROPN
gra-48	179	4	cen	cen	PROPN
gra-48	179	5	,	,	PUNCT
gra-48	179	6	guojun	guojun	PROPN
gra-48	179	7	ding	ding	NOUN
gra-48	179	8	,	,	PUNCT
gra-48	179	9	and	and	CCONJ
gra-48	179	10	wei	wei	PROPN
gra-48	179	11	wu	wu	PROPN
gra-48	179	12	mucinous	mucinous	ADJ
gra-48	179	13	colorectal	colorectal	ADJ
gra-48	179	14	adenocarcinoma	adenocarcinoma	NOUN
gra-48	179	15	:	:	PUNCT
gra-48	179	16	clinical	clinical	ADJ
gra-48	179	17	pathology	pathology	NOUN
gra-48	179	18	and	and	CCONJ
gra-48	179	19	treatment	treatment	NOUN
gra-48	179	20	optionscancer	optionscancer	PROPN
gra-48	179	21	commun	commun	PROPN
gra-48	179	22	(	(	PUNCT
gra-48	179	23	lond	lond	PROPN
gra-48	179	24	)	)	PUNCT
gra-48	179	25	.	.	PUNCT
gra-48	180	1	2019	2019	NUM
gra-48	180	2	;	;	PUNCT
gra-48	180	3	39	39	NUM
gra-48	180	4	:	:	SYM
gra-48	180	5	13	13	NUM
gra-48	180	6	.	.	X
gra-48	181	1	volume-8	volume-8	NUM
gra-48	181	2	,	,	PUNCT
gra-48	181	3	issue-9	issue-9	NUM
gra-48	181	4	,	,	PUNCT
gra-48	181	5	september-2019	september-2019	ADJ
gra-48	181	6	•	•	NUM
gra-48	181	7	print	print	NOUN
gra-48	181	8	issn	issn	PROPN
gra-48	181	9	no	no	NOUN
gra-48	181	10	.	.	PROPN
gra-48	182	1	2277	2277	NUM
gra-48	182	2	8160	8160	NUM
gra-48	182	3	•	•	NOUN
gra-48	182	4	doi	doi	NOUN
gra-48	182	5	:	:	PUNCT
gra-48	182	6	10.36106	10.36106	NUM
gra-48	182	7	/	/	SYM
gra-48	182	8	gjra	gjra	NOUN
gra-48	182	9	0	0	NUM
gra-48	182	10	1	1	NUM
gra-48	182	11	2	2	NUM
gra-48	182	12	3	3	NUM
gra-48	182	13	classic	classic	ADJ
gra-48	182	14	adenocarcinoma	adenocarcinoma	NOUN
gra-48	182	15	n:13	n:13	VERB
gra-48	182	16	54,16	54,16	NUM
gra-48	182	17	%	%	NOUN
gra-48	182	18	n:8	n:8	ADP
gra-48	182	19	33,3	33,3	NUM
gra-48	182	20	%	%	NOUN
gra-48	182	21	n:2	n:2	ADV
gra-48	182	22	8,33	8,33	NUM
gra-48	183	1	%	%	INTJ
gra-48	183	2	n:1	n:1	PRON
gra-48	183	3	4,16	4,16	NUM
gra-48	183	4	%	%	NOUN
gra-48	183	5	mucinous	mucinous	ADJ
gra-48	183	6	adenocarcinoma	adenocarcinoma	NOUN
gra-48	183	7	n:20	n:20	ADJ
gra-48	183	8	83,33	83,33	NUM
gra-48	183	9	%	%	NOUN
gra-48	183	10	n:2	n:2	ADV
gra-48	183	11	8,33	8,33	NUM
gra-48	183	12	%	%	NOUN
gra-48	183	13	n:2	n:2	ADV
gra-48	183	14	8,33	8,33	NUM
gra-48	183	15	%	%	NOUN
gra-48	183	16	0	0	NUM
gra-48	183	17	0	0	NUM
gra-48	183	18	%	%	NOUN
gra-48	183	19	0	0	NUM
gra-48	183	20	1	1	NUM
gra-48	183	21	2	2	NUM
gra-48	183	22	3	3	NUM
gra-48	183	23	classic	classic	ADJ
gra-48	183	24	adenocarcinoma	adenocarcinoma	NOUN
gra-48	183	25	0	0	NUM
gra-48	183	26	0	0	NUM
gra-48	183	27	%	%	NOUN
gra-48	183	28	0	0	NUM
gra-48	183	29	0	0	NUM
gra-48	183	30	%	%	NOUN
gra-48	183	31	n:12	n:12	CCONJ
gra-48	183	32	50	50	NUM
gra-48	183	33	%	%	NOUN
gra-48	183	34	n:12	n:12	CCONJ
gra-48	183	35	50	50	NUM
gra-48	183	36	%	%	NOUN
gra-48	183	37	mucinous	mucinous	ADJ
gra-48	183	38	adenocarcinoma	adenocarcinoma	NOUN
gra-48	183	39	8	8	NUM
gra-48	183	40	33,33	33,33	NUM
gra-48	183	41	%	%	NOUN
gra-48	183	42	0	0	NUM
gra-48	183	43	0	0	NUM
gra-48	183	44	%	%	NOUN
gra-48	183	45	0	0	NUM
gra-48	183	46	0	0	NUM
gra-48	183	47	%	%	NOUN
gra-48	183	48	0	0	NUM
gra-48	183	49	66,67	66,67	NUM
gra-48	183	50	%	%	NOUN
gra-48	183	51	24	24	NUM
gra-48	183	52	x	x	NOUN
gra-48	183	53	gjra	gjra	ADJ
gra-48	183	54	global	global	ADJ
gra-48	183	55	journal	journal	PROPN
gra-48	183	56	for	for	ADP
gra-48	183	57	research	research	NOUN
gra-48	183	58	analysis	analysis	NOUN