id	sid	tid	token	lemma	pos
gra-845	1	1	introduction	introduction	NOUN
gra-845	1	2	:	:	PUNCT
gra-845	1	3	valproic	valproic	ADJ
gra-845	1	4	acid	acid	NOUN
gra-845	1	5	(	(	PUNCT
gra-845	1	6	valproate	valproate	NOUN
gra-845	1	7	)	)	PUNCT
gra-845	1	8	is	be	AUX
gra-845	1	9	a	a	DET
gra-845	1	10	branched	branched	ADJ
gra-845	1	11	chain	chain	NOUN
gra-845	1	12	organic	organic	ADJ
gra-845	1	13	acid	acid	NOUN
gra-845	1	14	,	,	PUNCT
gra-845	1	15	used	use	VERB
gra-845	1	16	for	for	ADP
gra-845	1	17	treatment	treatment	NOUN
gra-845	1	18	of	of	ADP
gra-845	1	19	epilepsy	epilepsy	NOUN
gra-845	1	20	,	,	PUNCT
gra-845	1	21	migraine	migraine	VERB
gra-845	1	22	headache	headache	NOUN
gra-845	1	23	prophylaxis	prophylaxis	NOUN
gra-845	1	24	,	,	PUNCT
gra-845	1	25	bipolar	bipolar	ADJ
gra-845	1	26	disorders	disorder	NOUN
gra-845	1	27	and	and	CCONJ
gra-845	1	28	is	be	AUX
gra-845	1	29	a	a	DET
gra-845	1	30	renowned	renowned	ADJ
gra-845	1	31	cause	cause	NOUN
gra-845	1	32	of	of	ADP
gra-845	1	33	several	several	ADJ
gra-845	1	34	distinctive	distinctive	ADJ
gra-845	1	35	forms	form	NOUN
gra-845	1	36	of	of	ADP
gra-845	1	37	acute	acute	ADJ
gra-845	1	38	and	and	CCONJ
gra-845	1	39	chronic	chronic	ADJ
gra-845	1	40	liver	liver	NOUN
gra-845	1	41	injury	injury	NOUN
gra-845	1	42	.	.	PUNCT
gra-845	2	1	valproate	valproate	ADJ
gra-845	2	2	acts	act	NOUN
gra-845	2	3	by	by	ADP
gra-845	2	4	increasing	increase	VERB
gra-845	2	5	levels	level	NOUN
gra-845	2	6	of	of	ADP
gra-845	2	7	gamma	gamma	PROPN
gra-845	2	8	amino	amino	PROPN
gra-845	2	9	butyric	butyric	PROPN
gra-845	2	10	acid(gaba),a	acid(gaba),a	PROPN
gra-845	2	11	major	major	ADJ
gra-845	2	12	inhibitory	inhibitory	ADJ
gra-845	2	13	neuro	neuro	NOUN
gra-845	2	14	-	-	PUNCT
gra-845	2	15	transmitter	transmitter	NOUN
gra-845	2	16	in	in	ADP
gra-845	2	17	human	human	ADJ
gra-845	2	18	brain	brain	NOUN
gra-845	2	19	.	.	PUNCT
gra-845	3	1	valproate	valproate	ADJ
gra-845	3	2	has	have	VERB
gra-845	3	3	multiple	multiple	ADJ
gra-845	3	4	side	side	NOUN
gra-845	3	5	effects	effect	NOUN
gra-845	3	6	and	and	CCONJ
gra-845	3	7	clinically	clinically	ADV
gra-845	3	8	signicant	signicant	ADJ
gra-845	3	9	drug	drug	NOUN
gra-845	3	10	interactions	interaction	NOUN
gra-845	3	11	;	;	PUNCT
gra-845	3	12	common	common	ADJ
gra-845	3	13	side	side	NOUN
gra-845	3	14	effects	effect	NOUN
gra-845	3	15	include	include	VERB
gra-845	3	16	headache	headache	NOUN
gra-845	3	17	,	,	PUNCT
gra-845	3	18	insomnia	insomnia	NOUN
gra-845	3	19	,	,	PUNCT
gra-845	3	20	nervousness	nervousness	NOUN
gra-845	3	21	,	,	PUNCT
gra-845	3	22	somnolence	somnolence	NOUN
gra-845	3	23	,	,	PUNCT
gra-845	3	24	tremor	tremor	NOUN
gra-845	3	25	,	,	PUNCT
gra-845	3	26	blurred	blurred	ADJ
gra-845	3	27	vision	vision	NOUN
gra-845	3	28	,	,	PUNCT
gra-845	3	29	nausea	nausea	NOUN
gra-845	3	30	,	,	PUNCT
gra-845	3	31	weight	weight	NOUN
gra-845	3	32	gain	gain	NOUN
gra-845	3	33	and	and	CCONJ
gra-845	3	34	rash	rash	ADJ
gra-845	3	35	.	.	PUNCT
gra-845	4	1	more	more	ADV
gra-845	4	2	serious	serious	ADJ
gra-845	4	3	side	side	NOUN
gra-845	4	4	-	-	PUNCT
gra-845	4	5	effect	effect	NOUN
gra-845	4	6	includes	include	VERB
gra-845	4	7	fatal	fatal	ADJ
gra-845	4	8	liver	liver	NOUN
gra-845	4	9	damage	damage	NOUN
gra-845	4	10	.	.	PUNCT
gra-845	5	1	valproate	valproate	ADJ
gra-845	5	2	induced	induced	ADJ
gra-845	5	3	hepato	hepato	NOUN
gra-845	5	4	-	-	PUNCT
gra-845	5	5	toxicity	toxicity	NOUN
gra-845	5	6	can	can	AUX
gra-845	5	7	occur	occur	VERB
gra-845	5	8	in	in	ADP
gra-845	5	9	following	follow	VERB
gra-845	5	10	three	three	NUM
gra-845	5	11	:	:	PUNCT
gra-845	5	12	valproate	valproate	ADJ
gra-845	5	13	can	can	AUX
gra-845	5	14	cause	cause	VERB
gra-845	5	15	hepatotoxicity	hepatotoxicity	NOUN
gra-845	5	16	by	by	ADP
gra-845	5	17	3	3	NUM
gra-845	5	18	mechanisms	mechanism	NOUN
gra-845	5	19	1	1	NUM
gra-845	5	20	:	:	PUNCT
gra-845	5	21	hyperammonemia	hyperammonemia	NOUN
gra-845	5	22	with	with	ADP
gra-845	5	23	minimal	minimal	ADJ
gra-845	5	24	or	or	CCONJ
gra-845	5	25	no	no	DET
gra-845	5	26	evidence	evidence	NOUN
gra-845	5	27	of	of	ADP
gra-845	5	28	hepatic	hepatic	ADJ
gra-845	5	29	injury	injury	NOUN
gra-845	5	30	.	.	PUNCT
gra-845	6	1	this	this	DET
gra-845	6	2	syndrome	syndrome	NOUN
gra-845	6	3	presents	present	VERB
gra-845	6	4	with	with	ADP
gra-845	6	5	progressive	progressive	ADJ
gra-845	6	6	and	and	CCONJ
gra-845	6	7	episodic	episodic	ADJ
gra-845	6	8	confusion	confusion	NOUN
gra-845	6	9	followed	follow	VERB
gra-845	6	10	by	by	ADP
gra-845	6	11	obtundation	obtundation	NOUN
gra-845	6	12	and	and	CCONJ
gra-845	6	13	coma	coma	NOUN
gra-845	6	14	.	.	PUNCT
gra-845	7	1	diagnosis	diagnosis	NOUN
gra-845	7	2	can	can	AUX
gra-845	7	3	be	be	AUX
gra-845	7	4	made	make	VERB
gra-845	7	5	by	by	ADP
gra-845	7	6	elevation	elevation	NOUN
gra-845	7	7	in	in	ADP
gra-845	7	8	serum	serum	NOUN
gra-845	7	9	ammonia	ammonia	NOUN
gra-845	7	10	with	with	ADP
gra-845	7	11	normal	normal	ADJ
gra-845	7	12	serum	serum	NOUN
gra-845	7	13	amino	amino	NOUN
gra-845	7	14	-	-	PUNCT
gra-845	7	15	transferases	transferase	NOUN
gra-845	7	16	and	and	CCONJ
gra-845	7	17	bilirubin	bilirubin	NOUN
gra-845	7	18	levels	level	NOUN
gra-845	7	19	.	.	PUNCT
gra-845	8	1	this	this	DET
gra-845	8	2	syndrome	syndrome	NOUN
gra-845	8	3	resolves	resolve	NOUN
gra-845	8	4	within	within	ADP
gra-845	8	5	few	few	ADJ
gra-845	8	6	days	day	NOUN
gra-845	8	7	with	with	ADP
gra-845	8	8	stopping	stopping	NOUN
gra-845	8	9	of	of	ADP
gra-845	8	10	drug	drug	NOUN
gra-845	8	11	and	and	CCONJ
gra-845	8	12	more	more	ADV
gra-845	8	13	rapidly	rapidly	ADV
gra-845	8	14	with	with	ADP
gra-845	8	15	carnitidine	carnitidine	NOUN
gra-845	8	16	supplementation	supplementation	NOUN
gra-845	8	17	.	.	PUNCT
gra-845	9	1	2	2	NUM
gra-845	9	2	:	:	PUNCT
gra-845	9	3	acute	acute	VERB
gra-845	9	4	hepatocellular	hepatocellular	ADJ
gra-845	9	5	injury	injury	NOUN
gra-845	9	6	with	with	ADP
gra-845	9	7	jaundice	jaundice	NOUN
gra-845	9	8	and	and	CCONJ
gra-845	9	9	mixed	mixed	ADJ
gra-845	9	10	pattern	pattern	NOUN
gra-845	9	11	enzyme	enzyme	NOUN
gra-845	9	12	elevation	elevation	NOUN
gra-845	9	13	.	.	PUNCT
gra-845	10	1	onset	onset	NOUN
gra-845	10	2	is	be	AUX
gra-845	10	3	usually	usually	ADV
gra-845	10	4	within	within	ADP
gra-845	10	5	1	1	NUM
gra-845	10	6	-	-	SYM
gra-845	10	7	6	6	NUM
gra-845	10	8	months	month	NOUN
gra-845	10	9	of	of	ADP
gra-845	10	10	starting	start	VERB
gra-845	10	11	valproate	valproate	ADJ
gra-845	10	12	.	.	PUNCT
gra-845	11	1	mixed	mix	VERB
gra-845	11	2	pattern	pattern	NOUN
gra-845	11	3	or	or	CCONJ
gra-845	11	4	hepato	hepato	NOUN
gra-845	11	5	-	-	PUNCT
gra-845	11	6	cellular	cellular	ADJ
gra-845	11	7	pattern	pattern	NOUN
gra-845	11	8	of	of	ADP
gra-845	11	9	enzyme	enzyme	NOUN
gra-845	11	10	elevation	elevation	NOUN
gra-845	11	11	may	may	AUX
gra-845	11	12	be	be	AUX
gra-845	11	13	seen	see	VERB
gra-845	11	14	.	.	PUNCT
gra-845	12	1	fever	fever	NOUN
gra-845	12	2	,	,	PUNCT
gra-845	12	3	rash	rash	ADJ
gra-845	12	4	,	,	PUNCT
gra-845	12	5	eosinophilia	eosinophilia	PROPN
gra-845	12	6	are	be	AUX
gra-845	12	7	rare	rare	ADJ
gra-845	12	8	.	.	PUNCT
gra-845	13	1	liver	liver	NOUN
gra-845	13	2	histology	histology	NOUN
gra-845	13	3	s	s	PROPN
gra-845	13	4	/	/	SYM
gra-845	13	5	o	o	X
gra-845	13	6	microvesicular	microvesicular	ADJ
gra-845	13	7	steatosis	steatosis	NOUN
gra-845	13	8	with	with	ADP
gra-845	13	9	central	central	ADJ
gra-845	13	10	lobular	lobular	ADJ
gra-845	13	11	necrosis	necrosis	NOUN
gra-845	13	12	,	,	PUNCT
gra-845	13	13	mild	mild	ADJ
gra-845	13	14	to	to	ADP
gra-845	13	15	moderate	moderate	ADJ
gra-845	13	16	inammation	inammation	NOUN
gra-845	13	17	and	and	CCONJ
gra-845	13	18	steatosis	steatosis	NOUN
gra-845	13	19	.	.	PUNCT
gra-845	14	1	intravenous	intravenous	ADJ
gra-845	14	2	carnitine	carnitine	NOUN
gra-845	14	3	can	can	AUX
gra-845	14	4	be	be	AUX
gra-845	14	5	useful	useful	ADJ
gra-845	14	6	if	if	SCONJ
gra-845	14	7	given	give	VERB
gra-845	14	8	soon	soon	ADV
gra-845	14	9	after	after	ADP
gra-845	14	10	presentation	presentation	NOUN
gra-845	14	11	.	.	PUNCT
gra-845	15	1	3	3	NUM
gra-845	15	2	:	:	PUNCT
gra-845	15	3	acute	acute	ADJ
gra-845	15	4	hepatic	hepatic	ADJ
gra-845	15	5	injury	injury	NOUN
gra-845	15	6	with	with	ADP
gra-845	15	7	reye	reye	PROPN
gra-845	15	8	like	like	ADP
gra-845	15	9	syndrome	syndrome	PROPN
gra-845	15	10	usually	usually	ADV
gra-845	15	11	occurs	occur	VERB
gra-845	15	12	in	in	ADP
gra-845	15	13	children	child	NOUN
gra-845	15	14	on	on	ADP
gra-845	15	15	aspirin	aspirin	NOUN
gra-845	15	16	like	like	ADP
gra-845	15	17	agent	agent	NOUN
gra-845	15	18	following	follow	VERB
gra-845	15	19	inuenza	inuenza	PROPN
gra-845	15	20	or	or	CCONJ
gra-845	15	21	varicella	varicella	NOUN
gra-845	15	22	infection	infection	NOUN
gra-845	15	23	.	.	PUNCT
gra-845	16	1	child	child	NOUN
gra-845	16	2	on	on	ADP
gra-845	16	3	valproate	valproate	ADJ
gra-845	16	4	develops	develop	VERB
gra-845	16	5	fever	fever	NOUN
gra-845	16	6	,	,	PUNCT
gra-845	16	7	lethargy	lethargy	NOUN
gra-845	16	8	followed	follow	VERB
gra-845	16	9	by	by	ADP
gra-845	16	10	confusion	confusion	NOUN
gra-845	16	11	,	,	PUNCT
gra-845	16	12	stupor	stupor	NOUN
gra-845	16	13	and	and	CCONJ
gra-845	16	14	coma	coma	NOUN
gra-845	16	15	.	.	PUNCT
gra-845	17	1	laboratory	laboratory	NOUN
gra-845	17	2	nding	nde	VERB
gra-845	17	3	s	s	PROPN
gra-845	17	4	/	/	SYM
gra-845	17	5	o	o	NOUN
gra-845	17	6	raised	raise	VERB
gra-845	17	7	in	in	ADP
gra-845	17	8	ammonia	ammonia	ADJ
gra-845	17	9	level	level	NOUN
gra-845	17	10	with	with	ADP
gra-845	17	11	marked	mark	VERB
gra-845	17	12	alt	alt	VERB
gra-845	17	13	elevation	elevation	NOUN
gra-845	17	14	with	with	ADP
gra-845	17	15	normal	normal	ADJ
gra-845	17	16	bilirubin	bilirubin	NOUN
gra-845	17	17	level	level	NOUN
gra-845	17	18	.	.	PUNCT
gra-845	18	1	incidence	incidence	NOUN
gra-845	18	2	of	of	ADP
gra-845	18	3	valproate	valproate	ADJ
gra-845	18	4	induced	induced	ADJ
gra-845	18	5	hepatotoxicity	hepatotoxicity	NOUN
gra-845	18	6	in	in	ADP
gra-845	18	7	united	united	PROPN
gra-845	18	8	states	states	PROPN
gra-845	18	9	in	in	ADP
gra-845	18	10	2016	2016	NUM
gra-845	18	11	was	be	AUX
gra-845	18	12	3060	3060	NUM
gra-845	18	13	single	single	ADJ
gra-845	18	14	exposures	exposure	NOUN
gra-845	18	15	.	.	PUNCT
gra-845	19	1	the	the	DET
gra-845	19	2	international	international	ADJ
gra-845	19	3	frequency	frequency	NOUN
gra-845	19	4	of	of	ADP
gra-845	19	5	valproate	valproate	ADJ
gra-845	19	6	toxicity	toxicity	NOUN
gra-845	19	7	is	be	AUX
gra-845	19	8	unknown	unknown	ADJ
gra-845	19	9	.	.	PUNCT
gra-845	20	1	retrospective	retrospective	ADJ
gra-845	20	2	studies	study	NOUN
gra-845	20	3	indicate	indicate	VERB
gra-845	20	4	that	that	SCONJ
gra-845	20	5	patients	patient	NOUN
gra-845	20	6	under	under	ADP
gra-845	20	7	2	2	NUM
gra-845	20	8	years	year	NOUN
gra-845	20	9	of	of	ADP
gra-845	20	10	age	age	NOUN
gra-845	20	11	,	,	PUNCT
gra-845	20	12	those	those	PRON
gra-845	20	13	receiving	receive	VERB
gra-845	20	14	multiple	multiple	ADJ
gra-845	20	15	anticonvulsants	anticonvulsant	NOUN
gra-845	20	16	,	,	PUNCT
gra-845	20	17	and	and	CCONJ
gra-845	20	18	children	child	NOUN
gra-845	20	19	with	with	ADP
gra-845	20	20	underlying	underlie	VERB
gra-845	20	21	developmental	developmental	ADJ
gra-845	20	22	disorders	disorder	NOUN
gra-845	20	23	and	and	CCONJ
gra-845	20	24	inborn	inborn	ADJ
gra-845	20	25	errors	error	NOUN
gra-845	20	26	of	of	ADP
gra-845	20	27	metabolism	metabolism	NOUN
gra-845	20	28	may	may	AUX
gra-845	20	29	be	be	AUX
gra-845	20	30	at	at	ADP
gra-845	20	31	increased	increase	VERB
gra-845	20	32	risk	risk	NOUN
gra-845	20	33	clinical	clinical	ADJ
gra-845	20	34	features	feature	NOUN
gra-845	20	35	of	of	ADP
gra-845	20	36	valproate	valproate	ADJ
gra-845	20	37	induced	induced	ADJ
gra-845	20	38	hepato	hepato	NOUN
gra-845	20	39	-	-	PUNCT
gra-845	20	40	toxicity	toxicity	NOUN
gra-845	20	41	:	:	PUNCT
gra-845	20	42	symptoms	symptom	NOUN
gra-845	20	43	are	be	AUX
gra-845	20	44	accounted	account	VERB
gra-845	20	45	to	to	ADP
gra-845	20	46	hepatocyte	hepatocyte	NOUN
gra-845	20	47	damage	damage	NOUN
gra-845	20	48	,	,	PUNCT
gra-845	20	49	biliary	biliary	NOUN
gra-845	20	50	stasis	stasis	NOUN
gra-845	20	51	,	,	PUNCT
gra-845	20	52	hyperammonemia	hyperammonemia	NOUN
gra-845	20	53	.	.	PUNCT
gra-845	21	1	usually	usually	ADV
gra-845	21	2	occur	occur	VERB
gra-845	21	3	within	within	ADP
gra-845	21	4	1	1	NUM
gra-845	21	5	-	-	SYM
gra-845	21	6	6	6	NUM
gra-845	21	7	months	month	NOUN
gra-845	21	8	of	of	ADP
gra-845	21	9	starting	start	VERB
gra-845	21	10	drug	drug	NOUN
gra-845	21	11	.	.	PUNCT
gra-845	22	1	clinical	clinical	ADJ
gra-845	22	2	presentation	presentation	NOUN
gra-845	22	3	usually	usually	ADV
gra-845	22	4	begins	begin	VERB
gra-845	22	5	in	in	ADP
gra-845	22	6	form	form	NOUN
gra-845	22	7	of	of	ADP
gra-845	22	8	lethargy	lethargy	NOUN
gra-845	22	9	,	,	PUNCT
gra-845	22	10	nausea	nausea	NOUN
gra-845	22	11	,	,	PUNCT
gra-845	22	12	vomiting	vomiting	NOUN
gra-845	22	13	.	.	PUNCT
gra-845	23	1	soon	soon	ADV
gra-845	23	2	,	,	PUNCT
gra-845	23	3	jaundice	jaundice	NOUN
gra-845	23	4	,	,	PUNCT
gra-845	23	5	fever	fever	NOUN
gra-845	23	6	,	,	PUNCT
gra-845	23	7	rash	rash	ADJ
gra-845	23	8	,	,	PUNCT
gra-845	23	9	itching	itching	NOUN
gra-845	23	10	,	,	PUNCT
gra-845	23	11	abdominal	abdominal	ADJ
gra-845	23	12	pain	pain	NOUN
gra-845	23	13	may	may	AUX
gra-845	23	14	occur	occur	VERB
gra-845	23	15	.	.	PUNCT
gra-845	24	1	symptoms	symptom	NOUN
gra-845	24	2	depend	depend	VERB
gra-845	24	3	on	on	ADP
gra-845	24	4	form	form	NOUN
gra-845	24	5	of	of	ADP
gra-845	24	6	hepato	hepato	NOUN
gra-845	24	7	-	-	PUNCT
gra-845	24	8	toxicity	toxicity	NOUN
gra-845	24	9	which	which	PRON
gra-845	24	10	has	have	VERB
gra-845	24	11	varied	varied	ADJ
gra-845	24	12	manifestations	manifestation	NOUN
gra-845	24	13	in	in	ADP
gra-845	24	14	different	different	ADJ
gra-845	24	15	patients	patient	NOUN
gra-845	24	16	.	.	PUNCT
gra-845	25	1	patients	patient	NOUN
gra-845	25	2	with	with	ADP
gra-845	25	3	hyperammonemia	hyperammonemia	NOUN
gra-845	25	4	as	as	ADP
gra-845	25	5	predominant	predominant	ADJ
gra-845	25	6	form	form	NOUN
gra-845	25	7	of	of	ADP
gra-845	25	8	injury	injury	NOUN
gra-845	25	9	present	present	ADJ
gra-845	25	10	with	with	ADP
gra-845	25	11	altered	altered	ADJ
gra-845	25	12	sensorium	sensorium	NOUN
gra-845	25	13	,	,	PUNCT
gra-845	25	14	coma	coma	NOUN
gra-845	25	15	,	,	PUNCT
gra-845	25	16	features	feature	NOUN
gra-845	25	17	of	of	ADP
gra-845	25	18	hepatic	hepatic	ADJ
gra-845	25	19	encephalopathy	encephalopathy	NOUN
gra-845	25	20	.	.	PUNCT
gra-845	26	1	while	while	SCONJ
gra-845	26	2	those	those	PRON
gra-845	26	3	with	with	ADP
gra-845	26	4	hepatocellular	hepatocellular	NOUN
gra-845	26	5	or	or	CCONJ
gra-845	26	6	mixed	mixed	ADJ
gra-845	26	7	pattern	pattern	NOUN
gra-845	26	8	present	present	ADJ
gra-845	26	9	with	with	ADP
gra-845	26	10	symptoms	symptom	NOUN
gra-845	26	11	of	of	ADP
gra-845	26	12	obstructive	obstructive	ADJ
gra-845	26	13	jaundice	jaundice	NOUN
gra-845	26	14	like	like	ADP
gra-845	26	15	pruritus	pruritus	PROPN
gra-845	26	16	,	,	PUNCT
gra-845	26	17	right	right	ADJ
gra-845	26	18	hypochondrial	hypochondrial	ADJ
gra-845	26	19	pain	pain	NOUN
gra-845	26	20	,	,	PUNCT
gra-845	26	21	pale	pale	ADJ
gra-845	26	22	stools	stool	NOUN
gra-845	26	23	,	,	PUNCT
gra-845	26	24	dark	dark	ADJ
gra-845	26	25	urine	urine	NOUN
gra-845	26	26	and	and	CCONJ
gra-845	26	27	sclera	sclera	NOUN
gra-845	26	28	.	.	PUNCT
gra-845	27	1	children	child	NOUN
gra-845	27	2	with	with	ADP
gra-845	27	3	features	feature	NOUN
gra-845	27	4	of	of	ADP
gra-845	27	5	hepatic	hepatic	ADJ
gra-845	27	6	injury	injury	NOUN
gra-845	27	7	like	like	ADP
gra-845	27	8	rye	rye	NOUN
gra-845	27	9	syndrome	syndrome	PROPN
gra-845	27	10	present	present	ADJ
gra-845	27	11	with	with	ADP
gra-845	27	12	fever	fever	NOUN
gra-845	27	13	,	,	PUNCT
gra-845	27	14	lethargy	lethargy	NOUN
gra-845	27	15	,	,	PUNCT
gra-845	27	16	confusion	confusion	NOUN
gra-845	27	17	,	,	PUNCT
gra-845	27	18	coma	coma	NOUN
gra-845	27	19	.	.	PUNCT
gra-845	28	1	ii	ii	PROPN
gra-845	28	2	.	.	PUNCT
gra-845	29	1	case	case	NOUN
gra-845	29	2	report	report	NOUN
gra-845	29	3	:	:	PUNCT
gra-845	29	4	a	a	DET
gra-845	29	5	22	22	NUM
gra-845	29	6	year	year	NOUN
gra-845	29	7	old	old	ADJ
gra-845	29	8	male	male	NOUN
gra-845	29	9	,	,	PUNCT
gra-845	29	10	presented	present	VERB
gra-845	29	11	to	to	ADP
gra-845	29	12	the	the	DET
gra-845	29	13	emergency	emergency	NOUN
gra-845	29	14	room	room	NOUN
gra-845	29	15	of	of	ADP
gra-845	29	16	civil	civil	ADJ
gra-845	29	17	hospital	hospital	NOUN
gra-845	29	18	ahmedabad	ahmedabad	NOUN
gra-845	29	19	on	on	ADP
gra-845	29	20	6/1/2019	6/1/2019	NUM
gra-845	29	21	with	with	ADP
gra-845	29	22	chief	chief	ADJ
gra-845	29	23	complaints	complaint	NOUN
gra-845	29	24	of	of	ADP
gra-845	29	25	:	:	PUNCT
gra-845	29	26	yellowish	yellowish	ADJ
gra-845	29	27	urine	urine	NOUN
gra-845	29	28	and	and	CCONJ
gra-845	29	29	sclera	sclera	NOUN
gra-845	29	30	,	,	PUNCT
gra-845	29	31	anorexia	anorexia	PROPN
gra-845	29	32	,	,	PUNCT
gra-845	29	33	generalized	generalized	ADJ
gra-845	29	34	weakness	weakness	NOUN
gra-845	29	35	and	and	CCONJ
gra-845	29	36	easy	easy	ADJ
gra-845	29	37	fatiguability	fatiguability	NOUN
gra-845	29	38	and	and	CCONJ
gra-845	29	39	rash	rash	NOUN
gra-845	29	40	since	since	SCONJ
gra-845	29	41	10	10	NUM
gra-845	29	42	days	day	NOUN
gra-845	29	43	patient	patient	NOUN
gra-845	29	44	had	have	VERB
gra-845	29	45	no	no	DET
gra-845	29	46	history	history	NOUN
gra-845	29	47	of	of	ADP
gra-845	29	48	nausea	nausea	NOUN
gra-845	29	49	,	,	PUNCT
gra-845	29	50	vomiting	vomiting	NOUN
gra-845	29	51	,	,	PUNCT
gra-845	29	52	fever	fever	NOUN
gra-845	29	53	,	,	PUNCT
gra-845	29	54	abdominal	abdominal	ADJ
gra-845	29	55	pain	pain	NOUN
gra-845	29	56	,	,	PUNCT
gra-845	29	57	loose	loose	ADJ
gra-845	29	58	stools	stool	NOUN
gra-845	29	59	.	.	PUNCT
gra-845	30	1	patient	patient	NOUN
gra-845	30	2	was	be	AUX
gra-845	30	3	a	a	DET
gra-845	30	4	known	known	ADJ
gra-845	30	5	case	case	NOUN
gra-845	30	6	of	of	ADP
gra-845	30	7	seizure	seizure	NOUN
gra-845	30	8	disorder	disorder	NOUN
gra-845	30	9	since	since	SCONJ
gra-845	30	10	2010	2010	NUM
gra-845	30	11	and	and	CCONJ
gra-845	30	12	a	a	DET
gra-845	30	13	rare	rare	ADJ
gra-845	30	14	case	case	NOUN
gra-845	30	15	of	of	ADP
gra-845	30	16	valproate	valproate	ADJ
gra-845	30	17	induced	induced	ADJ
gra-845	30	18	hepato	hepato	NOUN
gra-845	30	19	-	-	PUNCT
gra-845	30	20	toxicity	toxicity	NOUN
gra-845	30	21	original	original	ADJ
gra-845	30	22	research	research	NOUN
gra-845	30	23	paper	paper	NOUN
gra-845	30	24	dr	dr	PROPN
gra-845	30	25	.	.	PROPN
gra-845	30	26	v.	v.	PROPN
gra-845	30	27	c.	c.	PROPN
gra-845	30	28	singel	singel	PROPN
gra-845	30	29	professor	professor	PROPN
gra-845	30	30	,	,	PUNCT
gra-845	30	31	head	head	NOUN
gra-845	30	32	of	of	ADP
gra-845	30	33	department	department	PROPN
gra-845	30	34	&	&	CCONJ
gra-845	30	35	head	head	PROPN
gra-845	30	36	of	of	ADP
gra-845	30	37	unit	unit	NOUN
gra-845	30	38	,	,	PUNCT
gra-845	30	39	department	department	NOUN
gra-845	30	40	of	of	ADP
gra-845	30	41	medicine	medicine	NOUN
gra-845	30	42	,	,	PUNCT
gra-845	30	43	b.	b.	PROPN
gra-845	30	44	j.	j.	PROPN
gra-845	30	45	medical	medical	PROPN
gra-845	30	46	college	college	PROPN
gra-845	30	47	,	,	PUNCT
gra-845	30	48	ahmedabad	ahmedabad	PROPN
gra-845	30	49	.	.	PUNCT
gra-845	31	1	medicine	medicine	NOUN
gra-845	31	2	drug	drug	NOUN
gra-845	31	3	induced	induce	VERB
gra-845	31	4	liver	liver	NOUN
gra-845	31	5	injury(dili	injury(dili	PROPN
gra-845	31	6	)	)	PUNCT
gra-845	31	7	can	can	AUX
gra-845	31	8	occur	occur	VERB
gra-845	31	9	owing	owe	VERB
gra-845	31	10	to	to	ADP
gra-845	31	11	a	a	DET
gra-845	31	12	dose	dose	NOUN
gra-845	31	13	dependent	dependent	ADJ
gra-845	31	14	or	or	CCONJ
gra-845	31	15	idiosyncratic	idiosyncratic	ADJ
gra-845	31	16	reaction	reaction	NOUN
gra-845	31	17	to	to	ADP
gra-845	31	18	a	a	DET
gra-845	31	19	drug	drug	NOUN
gra-845	31	20	.	.	PUNCT
gra-845	32	1	valproate	valproate	ADJ
gra-845	32	2	induced	induced	ADJ
gra-845	32	3	hepato	hepato	NOUN
gra-845	32	4	-	-	PUNCT
gra-845	32	5	toxicity	toxicity	NOUN
gra-845	32	6	can	can	AUX
gra-845	32	7	lead	lead	VERB
gra-845	32	8	to	to	ADP
gra-845	32	9	acute	acute	ADJ
gra-845	32	10	hepatic	hepatic	ADJ
gra-845	32	11	failure	failure	NOUN
gra-845	32	12	,	,	PUNCT
gra-845	32	13	occasionally	occasionally	ADV
gra-845	32	14	can	can	AUX
gra-845	32	15	progress	progress	VERB
gra-845	32	16	to	to	ADP
gra-845	32	17	fulminant	fulminant	ADJ
gra-845	32	18	hepatic	hepatic	ADJ
gra-845	32	19	failure	failure	NOUN
gra-845	32	20	and	and	CCONJ
gra-845	32	21	may	may	AUX
gra-845	32	22	require	require	VERB
gra-845	32	23	liver	liver	NOUN
gra-845	32	24	transplantation	transplantation	NOUN
gra-845	32	25	.	.	PUNCT
gra-845	33	1	valproate	valproate	ADJ
gra-845	33	2	being	be	AUX
gra-845	33	3	a	a	DET
gra-845	33	4	commonly	commonly	ADV
gra-845	33	5	used	use	VERB
gra-845	33	6	drug	drug	NOUN
gra-845	33	7	,	,	PUNCT
gra-845	33	8	most	most	ADJ
gra-845	33	9	physicians	physician	NOUN
gra-845	33	10	need	need	VERB
gra-845	33	11	to	to	PART
gra-845	33	12	exert	exert	VERB
gra-845	33	13	a	a	DET
gra-845	33	14	cautious	cautious	ADJ
gra-845	33	15	approach	approach	NOUN
gra-845	33	16	for	for	ADP
gra-845	33	17	judicious	judicious	ADJ
gra-845	33	18	use	use	NOUN
gra-845	33	19	of	of	ADP
gra-845	33	20	the	the	DET
gra-845	33	21	drug	drug	NOUN
gra-845	33	22	.	.	PUNCT
gra-845	34	1	hereby	hereby	ADV
gra-845	34	2	,	,	PUNCT
gra-845	34	3	we	we	PRON
gra-845	34	4	aim	aim	VERB
gra-845	34	5	to	to	PART
gra-845	34	6	discuss	discuss	VERB
gra-845	34	7	different	different	ADJ
gra-845	34	8	manifestations	manifestation	NOUN
gra-845	34	9	of	of	ADP
gra-845	34	10	valproate	valproate	ADJ
gra-845	34	11	induced	induced	ADJ
gra-845	34	12	hepato	hepato	NOUN
gra-845	34	13	-	-	PUNCT
gra-845	34	14	toxicity	toxicity	NOUN
gra-845	34	15	and	and	CCONJ
gra-845	34	16	it	it	PRON
gra-845	34	17	's	be	AUX
gra-845	34	18	medical	medical	ADJ
gra-845	34	19	management	management	NOUN
gra-845	34	20	.	.	PUNCT
gra-845	35	1	abstract	abstract	ADJ
gra-845	35	2	keywords	keyword	NOUN
gra-845	35	3	:	:	PUNCT
gra-845	35	4	valproate	valproate	ADJ
gra-845	35	5	hepato	hepato	NOUN
gra-845	35	6	-	-	PUNCT
gra-845	35	7	toxicity	toxicity	NOUN
gra-845	35	8	,	,	PUNCT
gra-845	35	9	hyperammonemia	hyperammonemia	NOUN
gra-845	35	10	,	,	PUNCT
gra-845	35	11	l	l	NOUN
gra-845	35	12	-	-	NOUN
gra-845	35	13	carnitine	carnitine	NOUN
gra-845	35	14	,	,	PUNCT
gra-845	35	15	reye	reye	NOUN
gra-845	35	16	like	like	ADP
gra-845	35	17	syndrome	syndrome	PROPN
gra-845	35	18	,	,	PUNCT
gra-845	35	19	hy	hy	NOUN
gra-845	35	20	's	's	PART
gra-845	35	21	law	law	NOUN
gra-845	35	22	.	.	PUNCT
gra-845	36	1	dr	dr	PROPN
gra-845	36	2	.	.	PROPN
gra-845	36	3	kartikeya	kartikeya	PROPN
gra-845	36	4	parmar	parmar	PROPN
gra-845	36	5	assistant	assistant	PROPN
gra-845	36	6	professor	professor	NOUN
gra-845	36	7	,	,	PUNCT
gra-845	36	8	department	department	NOUN
gra-845	36	9	of	of	ADP
gra-845	36	10	medicine	medicine	NOUN
gra-845	36	11	,	,	PUNCT
gra-845	36	12	b.	b.	PROPN
gra-845	36	13	j.	j.	PROPN
gra-845	36	14	medical	medical	PROPN
gra-845	36	15	college	college	PROPN
gra-845	36	16	,	,	PUNCT
gra-845	36	17	ahmedabad	ahmedabad	PROPN
gra-845	36	18	.	.	PUNCT
gra-845	37	1	dr	dr	PROPN
gra-845	37	2	.	.	PROPN
gra-845	37	3	khanjan	khanjan	PROPN
gra-845	37	4	patel	patel	PROPN
gra-845	37	5	*	*	PROPN
gra-845	37	6	third	third	ADJ
gra-845	37	7	year	year	NOUN
gra-845	37	8	resident	resident	NOUN
gra-845	37	9	,	,	PUNCT
gra-845	37	10	department	department	NOUN
gra-845	37	11	of	of	ADP
gra-845	37	12	medicine	medicine	NOUN
gra-845	37	13	,	,	PUNCT
gra-845	37	14	b.	b.	PROPN
gra-845	37	15	j.	j.	PROPN
gra-845	37	16	medical	medical	PROPN
gra-845	37	17	college	college	PROPN
gra-845	37	18	,	,	PUNCT
gra-845	37	19	ahmedabad	ahmedabad	PROPN
gra-845	37	20	.	.	PUNCT
gra-845	38	1	*	*	PUNCT
gra-845	38	2	corresponding	correspond	VERB
gra-845	38	3	author	author	NOUN
gra-845	38	4	dr	dr	PROPN
gra-845	38	5	.	.	PROPN
gra-845	38	6	vijay	vijay	PROPN
gra-845	38	7	dhalavaniya	dhalavaniya	PROPN
gra-845	38	8	third	third	ADJ
gra-845	38	9	year	year	NOUN
gra-845	38	10	resident	resident	NOUN
gra-845	38	11	,	,	PUNCT
gra-845	38	12	department	department	NOUN
gra-845	38	13	of	of	ADP
gra-845	38	14	medicine	medicine	NOUN
gra-845	38	15	,	,	PUNCT
gra-845	38	16	b.	b.	PROPN
gra-845	38	17	j.	j.	PROPN
gra-845	38	18	medical	medical	PROPN
gra-845	38	19	college	college	PROPN
gra-845	38	20	,	,	PUNCT
gra-845	38	21	ahmedabad	ahmedabad	PROPN
gra-845	38	22	.	.	PUNCT
gra-845	39	1	dr	dr	PROPN
gra-845	39	2	.	.	PROPN
gra-845	39	3	swansu	swansu	PROPN
gra-845	39	4	batra	batra	PROPN
gra-845	39	5	third	third	ADJ
gra-845	39	6	year	year	NOUN
gra-845	39	7	resident	resident	NOUN
gra-845	39	8	,	,	PUNCT
gra-845	39	9	department	department	NOUN
gra-845	39	10	of	of	ADP
gra-845	39	11	medicine	medicine	NOUN
gra-845	39	12	,	,	PUNCT
gra-845	39	13	b.	b.	PROPN
gra-845	39	14	j.	j.	PROPN
gra-845	39	15	medical	medical	PROPN
gra-845	39	16	college	college	PROPN
gra-845	39	17	,	,	PUNCT
gra-845	39	18	ahmedabad	ahmedabad	PROPN
gra-845	39	19	.	.	PUNCT
gra-845	40	1	volume-8	volume-8	NUM
gra-845	40	2	,	,	PUNCT
gra-845	40	3	issue-11	issue-11	PROPN
gra-845	40	4	,	,	PUNCT
gra-845	40	5	november-2019	november-2019	ADJ
gra-845	40	6	•	•	NOUN
gra-845	40	7	print	print	NOUN
gra-845	40	8	issn	issn	PROPN
gra-845	40	9	no	no	NOUN
gra-845	40	10	.	.	PROPN
gra-845	41	1	2277	2277	NUM
gra-845	41	2	8160	8160	NUM
gra-845	41	3	•	•	NOUN
gra-845	41	4	doi	doi	NOUN
gra-845	41	5	:	:	PUNCT
gra-845	41	6	10.36106	10.36106	NUM
gra-845	41	7	/	/	SYM
gra-845	41	8	gjra	gjra	NOUN
gra-845	41	9	32	32	NUM
gra-845	41	10	x	x	SYM
gra-845	41	11	gjra	gjra	PROPN
gra-845	41	12	global	global	ADJ
gra-845	41	13	journal	journal	PROPN
gra-845	41	14	for	for	ADP
gra-845	41	15	research	research	NOUN
gra-845	41	16	analysis	analysis	NOUN
gra-845	41	17	was	be	AUX
gra-845	41	18	on	on	ADP
gra-845	41	19	tab	tab	PROPN
gra-845	41	20	.	.	PUNCT
gra-845	42	1	phenytoin	phenytoin	PROPN
gra-845	42	2	(	(	PUNCT
gra-845	42	3	300	300	NUM
gra-845	42	4	mg	mg	NUM
gra-845	42	5	)	)	PUNCT
gra-845	42	6	since	since	SCONJ
gra-845	42	7	two	two	NUM
gra-845	42	8	years	year	NOUN
gra-845	42	9	,	,	PUNCT
gra-845	42	10	which	which	PRON
gra-845	42	11	he	he	PRON
gra-845	42	12	stopped	stop	VERB
gra-845	42	13	in	in	ADP
gra-845	42	14	2012	2012	NUM
gra-845	42	15	.	.	PUNCT
gra-845	43	1	he	he	PRON
gra-845	43	2	had	have	VERB
gra-845	43	3	3	3	NUM
gra-845	43	4	-	-	SYM
gra-845	43	5	4	4	NUM
gra-845	43	6	episodes	episode	NOUN
gra-845	43	7	of	of	ADP
gra-845	43	8	seizures	seizure	NOUN
gra-845	43	9	for	for	ADP
gra-845	43	10	which	which	PRON
gra-845	43	11	he	he	PRON
gra-845	43	12	was	be	AUX
gra-845	43	13	started	start	VERB
gra-845	43	14	on	on	ADP
gra-845	43	15	tablet	tablet	ADJ
gra-845	43	16	valproate	valproate	ADJ
gra-845	43	17	(	(	PUNCT
gra-845	43	18	500	500	NUM
gra-845	43	19	mg	mg	NUM
gra-845	43	20	)	)	PUNCT
gra-845	43	21	in	in	ADP
gra-845	43	22	october	october	PROPN
gra-845	43	23	2018	2018	NUM
gra-845	43	24	.	.	PUNCT
gra-845	44	1	within	within	ADP
gra-845	44	2	2	2	NUM
gra-845	44	3	months	month	NOUN
gra-845	44	4	of	of	ADP
gra-845	44	5	initiation	initiation	NOUN
gra-845	44	6	of	of	ADP
gra-845	44	7	tab	tab	NOUN
gra-845	44	8	.	.	PUNCT
gra-845	45	1	valproate	valproate	ADJ
gra-845	45	2	patient	patient	NOUN
gra-845	45	3	started	start	VERB
gra-845	45	4	developing	develop	VERB
gra-845	45	5	generalized	generalized	ADJ
gra-845	45	6	weakness	weakness	NOUN
gra-845	45	7	,	,	PUNCT
gra-845	45	8	yellow	yellow	ADJ
gra-845	45	9	discoloration	discoloration	NOUN
gra-845	45	10	of	of	ADP
gra-845	45	11	urine	urine	NOUN
gra-845	45	12	and	and	CCONJ
gra-845	45	13	sclera	sclera	NOUN
gra-845	45	14	,	,	PUNCT
gra-845	45	15	skin	skin	NOUN
gra-845	45	16	rash	rash	NOUN
gra-845	45	17	.	.	PUNCT
gra-845	46	1	he	he	PRON
gra-845	46	2	was	be	AUX
gra-845	46	3	admitted	admit	VERB
gra-845	46	4	for	for	ADP
gra-845	46	5	the	the	DET
gra-845	46	6	same	same	ADJ
gra-845	46	7	at	at	ADP
gra-845	46	8	some	some	DET
gra-845	46	9	local	local	ADJ
gra-845	46	10	hospital	hospital	NOUN
gra-845	46	11	in	in	ADP
gra-845	46	12	december	december	PROPN
gra-845	46	13	2018	2018	NUM
gra-845	46	14	and	and	CCONJ
gra-845	46	15	was	be	AUX
gra-845	46	16	later	later	ADV
gra-845	46	17	on	on	ADV
gra-845	46	18	referred	refer	VERB
gra-845	46	19	to	to	ADP
gra-845	46	20	civil	civil	ADJ
gra-845	46	21	hospital	hospital	NOUN
gra-845	46	22	ahmedabad	ahmedabad	NOUN
gra-845	46	23	for	for	ADP
gra-845	46	24	further	further	ADJ
gra-845	46	25	evaluation	evaluation	NOUN
gra-845	46	26	and	and	CCONJ
gra-845	46	27	management	management	NOUN
gra-845	46	28	in	in	ADP
gra-845	46	29	january	january	PROPN
gra-845	46	30	2019	2019	NUM
gra-845	46	31	.	.	PUNCT
gra-845	47	1	examination	examination	NOUN
gra-845	47	2	on	on	ADP
gra-845	47	3	examination	examination	NOUN
gra-845	47	4	patient	patient	NOUN
gra-845	47	5	was	be	AUX
gra-845	47	6	conscious	conscious	ADJ
gra-845	47	7	,	,	PUNCT
gra-845	47	8	oriented	oriented	ADJ
gra-845	47	9	.	.	PUNCT
gra-845	48	1	temperature	temperature	NOUN
gra-845	48	2	-	-	PUNCT
gra-845	48	3	normal	normal	ADJ
gra-845	48	4	pulse-82	pulse-82	PROPN
gra-845	48	5	/	/	SYM
gra-845	48	6	min	min	NOUN
gra-845	48	7	blood	blood	NOUN
gra-845	48	8	pressure-112/70	pressure-112/70	NOUN
gra-845	48	9	mmhg	mmhg	NOUN
gra-845	48	10	tonguepale	tonguepale	NOUN
gra-845	48	11	nail	nail	NOUN
gra-845	48	12	-	-	PUNCT
gra-845	48	13	pale	pale	NOUN
gra-845	48	14	bulbar	bulbar	NOUN
gra-845	48	15	conjunctiva	conjunctiva	NOUN
gra-845	48	16	,	,	PUNCT
gra-845	48	17	scleraicterus	scleraicterus	VERB
gra-845	48	18	present	present	ADJ
gra-845	48	19	respiratory	respiratory	ADJ
gra-845	48	20	system	system	NOUN
gra-845	48	21	-	-	PUNCT
gra-845	48	22	bilateral	bilateral	ADJ
gra-845	48	23	air	air	NOUN
gra-845	48	24	entry	entry	NOUN
gra-845	48	25	present	present	ADJ
gra-845	48	26	cardiovascular	cardiovascular	ADJ
gra-845	48	27	system	system	NOUN
gra-845	48	28	-	-	PUNCT
gra-845	48	29	first	first	ADJ
gra-845	48	30	and	and	CCONJ
gra-845	48	31	second	second	ADJ
gra-845	48	32	heart	heart	NOUN
gra-845	48	33	sounds	sound	VERB
gra-845	48	34	present	present	ADJ
gra-845	48	35	abdominal	abdominal	ADJ
gra-845	48	36	examination	examination	NOUN
gra-845	48	37	-	-	PUNCT
gra-845	48	38	no	no	DET
gra-845	48	39	palpable	palpable	ADJ
gra-845	48	40	hepato	hepato	NOUN
gra-845	48	41	-	-	PUNCT
gra-845	48	42	splenomegaly	splenomegaly	NOUN
gra-845	48	43	no	no	DET
gra-845	48	44	obvious	obvious	ADJ
gra-845	48	45	enlargement	enlargement	NOUN
gra-845	48	46	or	or	CCONJ
gra-845	48	47	swelling	swell	VERB
gra-845	48	48	central	central	ADJ
gra-845	48	49	nervous	nervous	ADJ
gra-845	48	50	systemconscious	systemconscious	ADJ
gra-845	48	51	,	,	PUNCT
gra-845	48	52	oriented	oriented	ADJ
gra-845	48	53	.	.	PUNCT
gra-845	49	1	tone	tone	NOUN
gra-845	49	2	,	,	PUNCT
gra-845	49	3	reexes	reexe	NOUN
gra-845	49	4	,	,	PUNCT
gra-845	49	5	power	power	NOUN
gra-845	49	6	,	,	PUNCT
gra-845	49	7	sensations	sensation	NOUN
gra-845	49	8	wnl	wnl	NOUN
gra-845	49	9	image	image	NOUN
gra-845	49	10	1	1	NUM
gra-845	49	11	:	:	PUNCT
gra-845	49	12	icteric	icteric	ADJ
gra-845	49	13	sclera	sclera	NOUN
gra-845	49	14	and	and	CCONJ
gra-845	49	15	under	under	NOUN
gra-845	49	16	-	-	PUNCT
gra-845	49	17	surface	surface	NOUN
gra-845	49	18	of	of	ADP
gra-845	49	19	tongue	tongue	NOUN
gra-845	49	20	image	image	NOUN
gra-845	49	21	2	2	NUM
gra-845	49	22	:	:	PUNCT
gra-845	49	23	rashes	rash	NOUN
gra-845	49	24	in	in	ADP
gra-845	49	25	palms	palm	NOUN
gra-845	49	26	and	and	CCONJ
gra-845	49	27	soles	sol	NOUN
gra-845	49	28	secondary	secondary	ADJ
gra-845	49	29	to	to	PART
gra-845	49	30	vaproate	vaproate	VERB
gra-845	49	31	exposure	exposure	NOUN
gra-845	49	32	volume-8	volume-8	NUM
gra-845	49	33	,	,	PUNCT
gra-845	49	34	issue-11	issue-11	PROPN
gra-845	49	35	,	,	PUNCT
gra-845	49	36	november-2019	november-2019	ADJ
gra-845	49	37	•	•	NOUN
gra-845	49	38	print	print	NOUN
gra-845	49	39	issn	issn	PROPN
gra-845	49	40	no	no	NOUN
gra-845	49	41	.	.	PROPN
gra-845	50	1	2277	2277	NUM
gra-845	50	2	8160	8160	NUM
gra-845	50	3	•	•	NOUN
gra-845	50	4	doi	doi	NOUN
gra-845	50	5	:	:	PUNCT
gra-845	50	6	10.36106	10.36106	NUM
gra-845	50	7	/	/	SYM
gra-845	50	8	gjra	gjra	NOUN
gra-845	50	9	laboratory	laboratory	NOUN
gra-845	50	10	investigations	investigation	NOUN
gra-845	50	11	hb	hb	X
gra-845	50	12	(	(	PUNCT
gra-845	50	13	gm	gm	PROPN
gra-845	50	14	/	/	SYM
gra-845	50	15	dl	dl	PROPN
gra-845	50	16	)	)	PUNCT
gra-845	50	17	total	total	ADJ
gra-845	50	18	wbc	wbc	PROPN
gra-845	50	19	count	count	NOUN
gra-845	50	20	(	(	PUNCT
gra-845	50	21	/cumm	/cumm	INTJ
gra-845	50	22	)	)	PUNCT
gra-845	50	23	bilirubin(mg	bilirubin(mg	PROPN
gra-845	50	24	/	/	SYM
gra-845	50	25	dl	dl	NOUN
gra-845	50	26	)	)	PUNCT
gra-845	50	27	sgot	sgot	NOUN
gra-845	50	28	(	(	PUNCT
gra-845	50	29	u	u	NOUN
gra-845	50	30	/	/	SYM
gra-845	50	31	l	l	NOUN
gra-845	50	32	)	)	PUNCT
gra-845	50	33	sgpt	sgpt	NOUN
gra-845	50	34	(	(	PUNCT
gra-845	50	35	u	u	NOUN
gra-845	50	36	/	/	SYM
gra-845	50	37	l	l	NOUN
gra-845	50	38	)	)	PUNCT
gra-845	50	39	alp	alp	NOUN
gra-845	50	40	(	(	PUNCT
gra-845	50	41	u	u	NOUN
gra-845	50	42	/	/	SYM
gra-845	50	43	l	l	NOUN
gra-845	50	44	)	)	PUNCT
gra-845	50	45	albumin	albumin	NOUN
gra-845	50	46	(	(	PUNCT
gra-845	50	47	gm	gm	PROPN
gra-845	50	48	/	/	SYM
gra-845	50	49	dl	dl	PROPN
gra-845	50	50	)	)	PUNCT
gra-845	50	51	inr	inr	PROPN
gra-845	50	52	creatinine	creatinine	NOUN
gra-845	50	53	(	(	PUNCT
gra-845	50	54	mg	mg	PROPN
gra-845	50	55	/	/	SYM
gra-845	50	56	dl	dl	NOUN
gra-845	50	57	)	)	PUNCT
gra-845	50	58	platelet	platelet	NOUN
gra-845	50	59	(	(	PUNCT
gra-845	50	60	lacs	lac	NOUN
gra-845	50	61	)	)	PUNCT
gra-845	50	62	sodium	sodium	NOUN
gra-845	50	63	(	(	PUNCT
gra-845	50	64	meq	meq	NOUN
gra-845	50	65	/	/	SYM
gra-845	50	66	l)direct	l)direct	ADJ
gra-845	50	67	indirect	indirect	ADJ
gra-845	50	68	total	total	NOUN
gra-845	50	69	10.3	10.3	NUM
gra-845	50	70	18,100	18,100	NUM
gra-845	50	71	12	12	NUM
gra-845	50	72	3	3	NUM
gra-845	50	73	15	15	NUM
gra-845	50	74	1745	1745	NUM
gra-845	50	75	2150	2150	NUM
gra-845	50	76	2.2.72	2.2.72	NUM
gra-845	50	77	5	5	NUM
gra-845	50	78	25,500	25,500	NUM
gra-845	50	79	14	14	NUM
gra-845	50	80	2.1	2.1	NUM
gra-845	50	81	16.1	16.1	NUM
gra-845	50	82	704	704	NUM
gra-845	50	83	1550	1550	NUM
gra-845	50	84	5.3	5.3	NUM
gra-845	50	85	3.8	3.8	NUM
gra-845	50	86	7	7	NUM
gra-845	50	87	4100	4100	NUM
gra-845	50	88	18	18	NUM
gra-845	50	89	8	8	NUM
gra-845	50	90	26	26	NUM
gra-845	50	91	232	232	NUM
gra-845	50	92	876	876	NUM
gra-845	50	93	125	125	NUM
gra-845	50	94	2.26	2.26	NUM
gra-845	50	95	1.6	1.6	NUM
gra-845	50	96	0.8	0.8	NUM
gra-845	50	97	2.6	2.6	NUM
gra-845	50	98	139	139	NUM
gra-845	50	99	10	10	NUM
gra-845	50	100	4600	4600	NUM
gra-845	50	101	28	28	NUM
gra-845	50	102	8	8	NUM
gra-845	50	103	36	36	NUM
gra-845	50	104	163	163	NUM
gra-845	50	105	312	312	NUM
gra-845	50	106	766	766	NUM
gra-845	50	107	3.1	3.1	NUM
gra-845	50	108	2.32	2.32	NUM
gra-845	50	109	1.2	1.2	NUM
gra-845	50	110	2.8	2.8	NUM
gra-845	50	111	141	141	NUM
gra-845	50	112	8.5	8.5	NUM
gra-845	50	113	5200	5200	NUM
gra-845	50	114	18	18	NUM
gra-845	50	115	4	4	NUM
gra-845	50	116	22	22	NUM
gra-845	50	117	164	164	NUM
gra-845	50	118	165	165	NUM
gra-845	50	119	1141	1141	NUM
gra-845	50	120	2.8	2.8	NUM
gra-845	50	121	1	1	NUM
gra-845	50	122	1.24	1.24	NUM
gra-845	50	123	2.6	2.6	NUM
gra-845	50	124	128	128	NUM
gra-845	50	125	tests	test	NOUN
gra-845	50	126	for	for	ADP
gra-845	50	127	hbsag	hbsag	NOUN
gra-845	50	128	,	,	PUNCT
gra-845	50	129	hcv	hcv	PROPN
gra-845	50	130	,	,	PUNCT
gra-845	50	131	hiv	hiv	PROPN
gra-845	50	132	,	,	PUNCT
gra-845	50	133	hav	hav	VERB
gra-845	50	134	,	,	PUNCT
gra-845	50	135	hev	hev	PROPN
gra-845	50	136	were	be	AUX
gra-845	50	137	negative	negative	ADJ
gra-845	50	138	.	.	PUNCT
gra-845	51	1	tests	test	NOUN
gra-845	51	2	for	for	ADP
gra-845	51	3	autoantibodies	autoantibody	NOUN
gra-845	51	4	asma	asma	PROPN
gra-845	51	5	,	,	PUNCT
gra-845	51	6	igg	igg	PROPN
gra-845	51	7	,	,	PUNCT
gra-845	51	8	ana	ana	PROPN
gra-845	51	9	,	,	PUNCT
gra-845	51	10	ama	ama	PROPN
gra-845	51	11	were	be	AUX
gra-845	51	12	negative	negative	ADJ
gra-845	51	13	.	.	PUNCT
gra-845	52	1	serum	serum	PROPN
gra-845	52	2	ceruloplasmin	ceruloplasmin	PROPN
gra-845	52	3	was	be	AUX
gra-845	52	4	normal	normal	ADJ
gra-845	52	5	serum	serum	NOUN
gra-845	52	6	ammonia	ammonia	NOUN
gra-845	52	7	–	–	PUNCT
gra-845	52	8	58	58	NUM
gra-845	52	9	µmol	µmol	NOUN
gra-845	52	10	/	/	SYM
gra-845	52	11	l	l	NOUN
gra-845	52	12	imaging	imaging	NOUN
gra-845	52	13	studies	study	NOUN
gra-845	52	14	and	and	CCONJ
gra-845	52	15	other	other	ADJ
gra-845	52	16	investigations	investigation	NOUN
gra-845	52	17	ecg	ecg	PROPN
gra-845	52	18	,	,	PUNCT
gra-845	52	19	chest	chest	NOUN
gra-845	52	20	xray	xray	NOUN
gra-845	52	21	-	-	PUNCT
gra-845	52	22	normal	normal	ADJ
gra-845	52	23	usg	usg	PROPN
gra-845	52	24	abdomen	abdomen	PROPN
gra-845	52	25	and	and	CCONJ
gra-845	52	26	pelvis	pelvis	NOUN
gra-845	52	27	-	-	PUNCT
gra-845	52	28	nad	nad	PROPN
gra-845	52	29	,	,	PUNCT
gra-845	52	30	with	with	ADP
gra-845	52	31	no	no	DET
gra-845	52	32	signs	sign	NOUN
gra-845	52	33	of	of	ADP
gra-845	52	34	biliary	biliary	ADJ
gra-845	52	35	obstruction	obstruction	NOUN
gra-845	52	36	cect	cect	NOUN
gra-845	52	37	abdomen	abdoman	NOUN
gra-845	52	38	and	and	CCONJ
gra-845	52	39	pelvis	pelvis	NOUN
gra-845	52	40	,	,	PUNCT
gra-845	52	41	mrcp	mrcp	ADJ
gra-845	52	42	-	-	ADJ
gra-845	52	43	nad	nad	ADJ
gra-845	52	44	slit	slit	NOUN
gra-845	52	45	lamp	lamp	PROPN
gra-845	52	46	examination	examination	NOUN
gra-845	52	47	-no	-no	ADP
gra-845	52	48	evidence	evidence	NOUN
gra-845	52	49	of	of	ADP
gra-845	52	50	kayser	kayser	PROPN
gra-845	52	51	fleischer	fleischer	PROPN
gra-845	52	52	ring	ring	NOUN
gra-845	52	53	.	.	PUNCT
gra-845	53	1	2d	2d	NUM
gra-845	53	2	echo	echo	NOUN
gra-845	53	3	-	-	PUNCT
gra-845	53	4	nad	nad	ADJ
gra-845	53	5	liver	liver	NOUN
gra-845	53	6	biopsy	biopsy	NOUN
gra-845	53	7	-	-	PUNCT
gra-845	53	8	lobular	lobular	ADJ
gra-845	53	9	architecture	architecture	NOUN
gra-845	53	10	of	of	ADP
gra-845	53	11	hepatic	hepatic	ADJ
gra-845	53	12	tissue	tissue	NOUN
gra-845	53	13	with	with	ADP
gra-845	53	14	extensive	extensive	ADJ
gra-845	53	15	sinusoidal	sinusoidal	ADJ
gra-845	53	16	dilation	dilation	NOUN
gra-845	53	17	,	,	PUNCT
gra-845	53	18	intrahepatic	intrahepatic	ADJ
gra-845	53	19	cholestasis	cholestasis	NOUN
gra-845	53	20	and	and	CCONJ
gra-845	53	21	mild	mild	ADJ
gra-845	53	22	hepatic	hepatic	ADJ
gra-845	53	23	steatosis	steatosis	NOUN
gra-845	53	24	.	.	PUNCT
gra-845	54	1	no	no	DET
gra-845	54	2	granulomatous	granulomatous	ADJ
gra-845	54	3	lesion	lesion	NOUN
gra-845	54	4	or	or	CCONJ
gra-845	54	5	sclerotic	sclerotic	ADJ
gra-845	54	6	changes	change	NOUN
gra-845	54	7	seen	see	VERB
gra-845	54	8	.	.	PUNCT
gra-845	55	1	course	course	NOUN
gra-845	55	2	in	in	ADP
gra-845	55	3	hospital	hospital	NOUN
gra-845	55	4	patient	patient	NOUN
gra-845	55	5	was	be	AUX
gra-845	55	6	admitted	admit	VERB
gra-845	55	7	at	at	ADP
gra-845	55	8	civil	civil	ADJ
gra-845	55	9	hospital	hospital	NOUN
gra-845	55	10	ahmedabad	ahmedabad	NOUN
gra-845	55	11	on	on	ADP
gra-845	55	12	6/1/2019.routine	6/1/2019.routine	NUM
gra-845	55	13	investigations	investigation	NOUN
gra-845	55	14	were	be	AUX
gra-845	55	15	suggestive	suggestive	ADJ
gra-845	55	16	of	of	ADP
gra-845	55	17	obstructive	obstructive	ADJ
gra-845	55	18	jaundice	jaundice	NOUN
gra-845	55	19	.	.	PUNCT
gra-845	56	1	tab	tab	NOUN
gra-845	56	2	.	.	PUNCT
gra-845	57	1	valproate	valproate	PROPN
gra-845	57	2	was	be	AUX
gra-845	57	3	stopped	stop	VERB
gra-845	57	4	and	and	CCONJ
gra-845	57	5	tab	tab	NOUN
gra-845	57	6	.	.	PUNCT
gra-845	58	1	levetiracetam	levetiracetam	PROPN
gra-845	58	2	was	be	AUX
gra-845	58	3	started	start	VERB
gra-845	58	4	in	in	ADP
gra-845	58	5	its	its	PRON
gra-845	58	6	place	place	NOUN
gra-845	58	7	.	.	PUNCT
gra-845	59	1	initially	initially	ADV
gra-845	59	2	supportive	supportive	ADJ
gra-845	59	3	treatment	treatment	NOUN
gra-845	59	4	was	be	AUX
gra-845	59	5	given	give	VERB
gra-845	59	6	in	in	ADP
gra-845	59	7	form	form	NOUN
gra-845	59	8	of	of	ADP
gra-845	59	9	tab	tab	NOUN
gra-845	59	10	ursetor	ursetor	NOUN
gra-845	59	11	(	(	PUNCT
gra-845	59	12	ursodeoxycholic	ursodeoxycholic	NOUN
gra-845	59	13	acid	acid	NOUN
gra-845	59	14	)	)	PUNCT
gra-845	59	15	300	300	NUM
gra-845	59	16	mg	mg	PROPN
gra-845	59	17	thrice	thrice	PROPN
gra-845	59	18	a	a	DET
gra-845	59	19	day	day	NOUN
gra-845	59	20	,	,	PUNCT
gra-845	59	21	liquid	liquid	ADJ
gra-845	59	22	lactulose	lactulose	NOUN
gra-845	59	23	30cc	30cc	PROPN
gra-845	59	24	thrice	thrice	NOUN
gra-845	59	25	a	a	DET
gra-845	59	26	day	day	NOUN
gra-845	59	27	,	,	PUNCT
gra-845	59	28	lactulose	lactulose	NOUN
gra-845	59	29	enema	enema	NOUN
gra-845	59	30	,	,	PUNCT
gra-845	59	31	intravenous	intravenous	ADJ
gra-845	59	32	uids	uids	PRON
gra-845	59	33	containing	contain	VERB
gra-845	59	34	dextrose	dextrose	NOUN
gra-845	59	35	over	over	ADP
gra-845	59	36	a	a	DET
gra-845	59	37	period	period	NOUN
gra-845	59	38	of	of	ADP
gra-845	59	39	5	5	NUM
gra-845	59	40	days	day	NOUN
gra-845	59	41	.	.	PUNCT
gra-845	60	1	intravenous	intravenous	ADJ
gra-845	60	2	n	n	CCONJ
gra-845	60	3	-	-	PUNCT
gra-845	60	4	acetylcysteine	acetylcysteine	NOUN
gra-845	60	5	over	over	ADP
gra-845	60	6	21	21	NUM
gra-845	60	7	hours	hour	NOUN
gra-845	60	8	was	be	AUX
gra-845	60	9	given	give	VERB
gra-845	60	10	in	in	ADP
gra-845	60	11	form	form	NOUN
gra-845	60	12	of	of	ADP
gra-845	60	13	divided	divide	VERB
gra-845	60	14	doses	dose	NOUN
gra-845	60	15	ie	ie	X
gra-845	60	16	50mg	50mg	PROPN
gra-845	60	17	/	/	SYM
gra-845	60	18	kg	kg	PROPN
gra-845	60	19	over	over	ADP
gra-845	60	20	1	1	NUM
gra-845	60	21	hr	hr	NOUN
gra-845	60	22	,	,	PUNCT
gra-845	60	23	150	150	NUM
gra-845	60	24	mg	mg	NUM
gra-845	60	25	/	/	SYM
gra-845	60	26	kg	kg	NOUN
gra-845	60	27	over	over	ADP
gra-845	60	28	4	4	NUM
gra-845	60	29	hrs,100mg	hrs,100mg	NOUN
gra-845	60	30	/	/	SYM
gra-845	60	31	kg	kg	NOUN
gra-845	60	32	over	over	ADP
gra-845	60	33	16	16	NUM
gra-845	60	34	hrs	hrs	NOUN
gra-845	60	35	.	.	PUNCT
gra-845	61	1	during	during	ADP
gra-845	61	2	this	this	DET
gra-845	61	3	period	period	NOUN
gra-845	61	4	,	,	PUNCT
gra-845	61	5	complete	complete	ADJ
gra-845	61	6	workup	workup	PROPN
gra-845	61	7	was	be	AUX
gra-845	61	8	done	do	VERB
gra-845	61	9	.	.	PUNCT
gra-845	62	1	all	all	DET
gra-845	62	2	other	other	ADJ
gra-845	62	3	causes	cause	NOUN
gra-845	62	4	of	of	ADP
gra-845	62	5	jaundice	jaundice	NOUN
gra-845	62	6	ie	ie	X
gra-845	62	7	infectious	infectious	ADJ
gra-845	62	8	,	,	PUNCT
gra-845	62	9	metabolic	metabolic	NOUN
gra-845	62	10	,	,	PUNCT
gra-845	62	11	genetic	genetic	ADJ
gra-845	62	12	;	;	PUNCT
gra-845	62	13	mainly	mainly	ADV
gra-845	62	14	of	of	ADP
gra-845	62	15	obstructive	obstructive	ADJ
gra-845	62	16	variety	variety	NOUN
gra-845	62	17	were	be	AUX
gra-845	62	18	ruled	rule	VERB
gra-845	62	19	out	out	ADP
gra-845	62	20	.	.	PUNCT
gra-845	63	1	a	a	DET
gra-845	63	2	nal	nal	ADJ
gra-845	63	3	diagnosis	diagnosis	NOUN
gra-845	63	4	of	of	ADP
gra-845	63	5	valproate	valproate	ADJ
gra-845	63	6	induced	induced	ADJ
gra-845	63	7	hepato	hepato	NOUN
gra-845	63	8	-	-	PUNCT
gra-845	63	9	toxicity	toxicity	NOUN
gra-845	63	10	was	be	AUX
gra-845	63	11	established	establish	VERB
gra-845	63	12	post	post	NOUN
gra-845	63	13	liver	liver	NOUN
gra-845	63	14	biopsy	biopsy	NOUN
gra-845	63	15	.	.	PUNCT
gra-845	64	1	patient	patient	NOUN
gra-845	64	2	was	be	AUX
gra-845	64	3	started	start	VERB
gra-845	64	4	on	on	ADP
gra-845	64	5	carnitine	carnitine	NOUN
gra-845	64	6	and	and	CCONJ
gra-845	64	7	other	other	ADJ
gra-845	64	8	antioxidants	antioxidant	NOUN
gra-845	64	9	.	.	PUNCT
gra-845	65	1	carnitine	carnitine	NOUN
gra-845	65	2	was	be	AUX
gra-845	65	3	given	give	VERB
gra-845	65	4	intravenously	intravenously	ADV
gra-845	65	5	in	in	ADP
gra-845	65	6	the	the	DET
gra-845	65	7	loading	loading	NOUN
gra-845	65	8	dose	dose	NOUN
gra-845	65	9	of	of	ADP
gra-845	65	10	100mg	100mg	PROPN
gra-845	65	11	/	/	SYM
gra-845	65	12	kg	kg	PROPN
gra-845	65	13	over	over	ADP
gra-845	65	14	30	30	NUM
gra-845	65	15	minutes	minute	NOUN
gra-845	65	16	and	and	CCONJ
gra-845	65	17	15mg	15mg	NOUN
gra-845	65	18	/	/	SYM
gra-845	65	19	kg	kg	NOUN
gra-845	65	20	every	every	DET
gra-845	65	21	4	4	NUM
gra-845	65	22	hours	hour	NOUN
gra-845	65	23	till	till	SCONJ
gra-845	65	24	3	3	NUM
gra-845	65	25	days	day	NOUN
gra-845	65	26	.	.	PUNCT
gra-845	66	1	as	as	SCONJ
gra-845	66	2	patient	patient	NOUN
gra-845	66	3	's	's	PART
gra-845	66	4	liver	liver	NOUN
gra-845	66	5	function	function	NOUN
gra-845	66	6	test	test	NOUN
gra-845	66	7	was	be	AUX
gra-845	66	8	not	not	PART
gra-845	66	9	improving	improve	VERB
gra-845	66	10	signicantly	signicantly	ADV
gra-845	66	11	and	and	CCONJ
gra-845	66	12	had	have	AUX
gra-845	66	13	developed	develop	VERB
gra-845	66	14	dilin	dilin	NOUN
gra-845	66	15	grade	grade	NOUN
gra-845	66	16	4	4	NUM
gra-845	66	17	(	(	PUNCT
gra-845	66	18	severe	severe	ADJ
gra-845	66	19	)	)	PUNCT
gra-845	66	20	acute	acute	ADJ
gra-845	66	21	hepatic	hepatic	ADJ
gra-845	66	22	failure	failure	NOUN
gra-845	66	23	,	,	PUNCT
gra-845	66	24	patient	patient	NOUN
gra-845	66	25	was	be	AUX
gra-845	66	26	referred	refer	VERB
gra-845	66	27	to	to	ADP
gra-845	66	28	ikdrc	ikdrc	NOUN
gra-845	66	29	at	at	ADP
gra-845	66	30	civil	civil	ADJ
gra-845	66	31	hospital	hospital	NOUN
gra-845	66	32	ahmedabad	ahmedabad	PROPN
gra-845	66	33	for	for	ADP
gra-845	66	34	liver	liver	NOUN
gra-845	66	35	transplantation	transplantation	NOUN
gra-845	66	36	.	.	PUNCT
gra-845	67	1	i.	i.	NOUN
gra-845	67	2	discussion	discussion	NOUN
gra-845	67	3	regarding	regard	VERB
gra-845	67	4	treatment	treatment	NOUN
gra-845	67	5	of	of	ADP
gra-845	67	6	valproate	valproate	ADJ
gra-845	67	7	induced	induced	ADJ
gra-845	67	8	hepato	hepato	NOUN
gra-845	67	9	-	-	PUNCT
gra-845	67	10	toxicity	toxicity	NOUN
gra-845	67	11	the	the	DET
gra-845	67	12	offending	offend	VERB
gra-845	67	13	drug	drug	NOUN
gra-845	67	14	i.e.	i.e.	X
gra-845	67	15	valproate	valproate	ADJ
gra-845	67	16	is	be	AUX
gra-845	67	17	to	to	PART
gra-845	67	18	be	be	AUX
gra-845	67	19	stopped	stop	VERB
gra-845	67	20	rstly	rstly	ADV
gra-845	67	21	.	.	PUNCT
gra-845	68	1	importantly	importantly	ADV
gra-845	68	2	,	,	PUNCT
gra-845	68	3	carnitine	carnitine	NOUN
gra-845	68	4	appears	appear	VERB
gra-845	68	5	to	to	PART
gra-845	68	6	be	be	AUX
gra-845	68	7	a	a	DET
gra-845	68	8	specic	specic	NOUN
gra-845	68	9	antidote	antidote	NOUN
gra-845	68	10	for	for	ADP
gra-845	68	11	valproate	valproate	ADJ
gra-845	68	12	hepatotoxicity	hepatotoxicity	NOUN
gra-845	68	13	.	.	PUNCT
gra-845	69	1	l	l	NOUN
gra-845	69	2	-	-	NOUN
gra-845	69	3	carnitine	carnitine	NOUN
gra-845	69	4	,	,	PUNCT
gra-845	69	5	a	a	DET
gra-845	69	6	water	water	NOUN
gra-845	69	7	soluble	soluble	ADJ
gra-845	69	8	amino	amino	NOUN
gra-845	69	9	acid	acid	NOUN
gra-845	69	10	,	,	PUNCT
gra-845	69	11	is	be	AUX
gra-845	69	12	indicated	indicate	VERB
gra-845	69	13	in	in	ADP
gra-845	69	14	the	the	DET
gra-845	69	15	management	management	NOUN
gra-845	69	16	of	of	ADP
gra-845	69	17	patients	patient	NOUN
gra-845	69	18	that	that	PRON
gra-845	69	19	develop	develop	VERB
gra-845	69	20	hyperammonemia	hyperammonemia	NOUN
gra-845	69	21	(	(	PUNCT
gra-845	69	22	serum	serum	NOUN
gra-845	69	23	ammonia	ammonia	NOUN
gra-845	69	24	concentrations	concentration	NOUN
gra-845	69	25	>	>	X
gra-845	69	26	80	80	NUM
gra-845	69	27	µg	µg	NOUN
gra-845	69	28	/	/	SYM
gra-845	69	29	dl	dl	NOUN
gra-845	69	30	)	)	PUNCT
gra-845	69	31	and	and	CCONJ
gra-845	69	32	hepatic	hepatic	NOUN
gra-845	69	33	toxicity	toxicity	NOUN
gra-845	69	34	associated	associate	VERB
gra-845	69	35	with	with	ADP
gra-845	69	36	both	both	CCONJ
gra-845	69	37	therapeutic	therapeutic	ADJ
gra-845	69	38	dosing	dose	VERB
gra-845	69	39	and	and	CCONJ
gra-845	69	40	acute	acute	ADJ
gra-845	69	41	overdose	overdose	NOUN
gra-845	69	42	of	of	ADP
gra-845	69	43	valproic	valproic	ADJ
gra-845	69	44	acid	acid	NOUN
gra-845	69	45	.	.	PUNCT
gra-845	70	1	valproic	valproic	ADJ
gra-845	70	2	acid	acid	NOUN
gra-845	70	3	is	be	AUX
gra-845	70	4	commonly	commonly	ADV
gra-845	70	5	used	use	VERB
gra-845	70	6	in	in	ADP
gra-845	70	7	the	the	DET
gra-845	70	8	management	management	NOUN
gra-845	70	9	of	of	ADP
gra-845	70	10	seizure	seizure	NOUN
gra-845	70	11	and	and	CCONJ
gra-845	70	12	psychiatric	psychiatric	ADJ
gra-845	70	13	mood	mood	NOUN
gra-845	70	14	disorders	disorder	NOUN
gra-845	70	15	.	.	PUNCT
gra-845	71	1	deciencies	deciencie	NOUN
gra-845	71	2	in	in	ADP
gra-845	71	3	dietary	dietary	ADJ
gra-845	71	4	intake	intake	NOUN
gra-845	71	5	and	and	CCONJ
gra-845	71	6	endogenous	endogenous	ADJ
gra-845	71	7	production	production	NOUN
gra-845	71	8	of	of	ADP
gra-845	71	9	l	l	NOUN
gra-845	71	10	-	-	ADJ
gra-845	71	11	carnitine	carnitine	ADJ
gra-845	71	12	increase	increase	NOUN
gra-845	71	13	the	the	DET
gra-845	71	14	risk	risk	NOUN
gra-845	71	15	of	of	ADP
gra-845	71	16	developing	develop	VERB
gra-845	71	17	hyperammonemia	hyperammonemia	NOUN
gra-845	71	18	fol	fol	NOUN
gra-845	71	19	lowing	low	VERB
gra-845	71	20	valproic	valproic	ADJ
gra-845	71	21	acid	acid	NOUN
gra-845	71	22	exposure	exposure	NOUN
gra-845	71	23	.	.	PUNCT
gra-845	72	1	high	high	ADJ
gra-845	72	2	ammonia	ammonia	NOUN
gra-845	72	3	concentrations	concentration	NOUN
gra-845	72	4	may	may	AUX
gra-845	72	5	produce	produce	VERB
gra-845	72	6	encephalopathy	encephalopathy	NOUN
gra-845	72	7	characterized	characterize	VERB
gra-845	72	8	by	by	ADP
gra-845	72	9	altered	alter	VERB
gra-845	72	10	mental	mental	ADJ
gra-845	72	11	status	status	NOUN
gra-845	72	12	or	or	CCONJ
gra-845	72	13	seizures	seizure	NOUN
gra-845	72	14	and	and	CCONJ
gra-845	72	15	possibly	possibly	ADV
gra-845	72	16	death	death	NOUN
gra-845	72	17	if	if	SCONJ
gra-845	72	18	not	not	PART
gra-845	72	19	recognized	recognize	VERB
gra-845	72	20	.	.	PUNCT
gra-845	73	1	prompt	prompt	ADJ
gra-845	73	2	administration	administration	NOUN
gra-845	73	3	of	of	ADP
gra-845	73	4	carnitine	carnitine	NOUN
gra-845	73	5	(	(	PUNCT
gra-845	73	6	particularly	particularly	ADV
gra-845	73	7	when	when	SCONJ
gra-845	73	8	given	give	VERB
gra-845	73	9	intravenously	intravenously	ADV
gra-845	73	10	)	)	PUNCT
gra-845	73	11	improves	improve	VERB
gra-845	73	12	survival	survival	NOUN
gra-845	73	13	in	in	ADP
gra-845	73	14	acute	acute	ADJ
gra-845	73	15	valproate	valproate	ADJ
gra-845	73	16	hepatotoxicity	hepatotoxicity	NOUN
gra-845	73	17	.	.	PUNCT
gra-845	74	1	the	the	DET
gra-845	74	2	typically	typically	ADV
gra-845	74	3	recommended	recommend	VERB
gra-845	74	4	dose	dose	NOUN
gra-845	74	5	is	be	AUX
gra-845	74	6	100	100	NUM
gra-845	74	7	mg	mg	NOUN
gra-845	74	8	/	/	SYM
gra-845	74	9	kg	kg	PROPN
gra-845	74	10	intravenously	intravenously	ADV
gra-845	74	11	over	over	ADP
gra-845	74	12	30	30	NUM
gra-845	74	13	minutes	minute	NOUN
gra-845	74	14	(	(	PUNCT
gra-845	74	15	but	but	CCONJ
gra-845	74	16	less	less	ADJ
gra-845	74	17	than	than	ADP
gra-845	74	18	6	6	NUM
gra-845	74	19	grams	gram	NOUN
gra-845	74	20	)	)	PUNCT
gra-845	74	21	,	,	PUNCT
gra-845	74	22	followed	follow	VERB
gra-845	74	23	by	by	ADP
gra-845	74	24	15	15	NUM
gra-845	74	25	mg	mg	NOUN
gra-845	74	26	/	/	SYM
gra-845	74	27	kg	kg	NOUN
gra-845	74	28	every	every	DET
gra-845	74	29	four	four	NUM
gra-845	74	30	hours	hour	NOUN
gra-845	74	31	until	until	ADP
gra-845	74	32	clinical	clinical	ADJ
gra-845	74	33	improvement	improvement	NOUN
gra-845	74	34	.	.	PUNCT
gra-845	75	1	other	other	ADJ
gra-845	75	2	supportive	supportive	ADJ
gra-845	75	3	management	management	NOUN
gra-845	75	4	for	for	ADP
gra-845	75	5	liver	liver	NOUN
gra-845	75	6	failure	failure	NOUN
gra-845	75	7	includes	include	VERB
gra-845	75	8	intravenous	intravenous	ADJ
gra-845	75	9	dextrose	dextrose	NOUN
gra-845	75	10	containing	contain	VERB
gra-845	75	11	uids	uid	NOUN
gra-845	75	12	,	,	PUNCT
gra-845	75	13	syrup	syrup	NOUN
gra-845	75	14	lactulose	lactulose	NOUN
gra-845	75	15	,	,	PUNCT
gra-845	75	16	ursodeoxycholic	ursodeoxycholic	PROPN
gra-845	75	17	acid	acid	PROPN
gra-845	75	18	.	.	PUNCT
gra-845	76	1	n	n	CCONJ
gra-845	76	2	-	-	PUNCT
gra-845	76	3	acetylcysteine	acetylcysteine	VERB
gra-845	76	4	an	an	DET
gra-845	76	5	antioxidant	antioxidant	NOUN
gra-845	76	6	commonly	commonly	ADV
gra-845	76	7	used	use	VERB
gra-845	76	8	in	in	ADP
gra-845	76	9	paracetamol	paracetamol	NOUN
gra-845	76	10	poisoning	poisoning	NOUN
gra-845	76	11	,	,	PUNCT
gra-845	76	12	can	can	AUX
gra-845	76	13	be	be	AUX
gra-845	76	14	used	use	VERB
gra-845	76	15	in	in	ADP
gra-845	76	16	acute	acute	ADJ
gra-845	76	17	hepatic	hepatic	ADJ
gra-845	76	18	failure	failure	NOUN
gra-845	76	19	due	due	ADP
gra-845	76	20	to	to	ADP
gra-845	76	21	it	it	PRON
gra-845	76	22	's	be	AUX
gra-845	76	23	hepato	hepato	NOUN
gra-845	76	24	-	-	PUNCT
gra-845	76	25	protective	protective	ADJ
gra-845	76	26	x	x	SYM
gra-845	76	27	33gjra	33gjra	NUM
gra-845	76	28	global	global	ADJ
gra-845	76	29	journal	journal	NOUN
gra-845	76	30	for	for	ADP
gra-845	76	31	research	research	NOUN
gra-845	76	32	analysis	analysis	NOUN
gra-845	76	33	volume-8	volume-8	NUM
gra-845	76	34	,	,	PUNCT
gra-845	76	35	issue-11	issue-11	PROPN
gra-845	76	36	,	,	PUNCT
gra-845	76	37	november-2019	november-2019	ADJ
gra-845	76	38	•	•	NOUN
gra-845	76	39	print	print	NOUN
gra-845	76	40	issn	issn	PROPN
gra-845	76	41	no	no	NOUN
gra-845	76	42	.	.	PROPN
gra-845	77	1	2277	2277	NUM
gra-845	77	2	8160	8160	NUM
gra-845	77	3	•	•	NOUN
gra-845	77	4	doi	doi	NOUN
gra-845	77	5	:	:	PUNCT
gra-845	77	6	10.36106	10.36106	NUM
gra-845	77	7	/	/	SYM
gra-845	77	8	gjra	gjra	ADJ
gra-845	77	9	effect	effect	NOUN
gra-845	77	10	.	.	PUNCT
gra-845	78	1	patients	patient	NOUN
gra-845	78	2	not	not	PART
gra-845	78	3	improving	improve	VERB
gra-845	78	4	with	with	ADP
gra-845	78	5	medical	medical	ADJ
gra-845	78	6	management	management	NOUN
gra-845	78	7	and	and	CCONJ
gra-845	78	8	progressing	progress	VERB
gra-845	78	9	towards	towards	ADP
gra-845	78	10	acute	acute	ADJ
gra-845	78	11	hepatic	hepatic	ADJ
gra-845	78	12	failure	failure	NOUN
gra-845	78	13	may	may	AUX
gra-845	78	14	require	require	VERB
gra-845	78	15	liver	liver	NOUN
gra-845	78	16	transplantation	transplantation	NOUN
gra-845	78	17	at	at	ADP
gra-845	78	18	the	the	DET
gra-845	78	19	earliest	early	ADJ
gra-845	78	20	.	.	PUNCT
gra-845	79	1	iv	iv	X
gra-845	79	2	.	.	PUNCT
gra-845	79	3	key	key	ADJ
gra-845	79	4	message	message	NOUN
gra-845	79	5	valproate	valproate	ADJ
gra-845	79	6	induced	induce	VERB
gra-845	79	7	hepato	hepato	NOUN
gra-845	79	8	-	-	PUNCT
gra-845	79	9	toxicity	toxicity	NOUN
gra-845	79	10	is	be	AUX
gra-845	79	11	a	a	DET
gra-845	79	12	diagnosis	diagnosis	NOUN
gra-845	79	13	of	of	ADP
gra-845	79	14	exclusion	exclusion	NOUN
gra-845	79	15	.	.	PUNCT
gra-845	80	1	only	only	ADV
gra-845	80	2	after	after	ADP
gra-845	80	3	ruling	rule	VERB
gra-845	80	4	out	out	ADP
gra-845	80	5	all	all	DET
gra-845	80	6	other	other	ADJ
gra-845	80	7	causes	cause	NOUN
gra-845	80	8	,	,	PUNCT
gra-845	80	9	should	should	AUX
gra-845	80	10	a	a	DET
gra-845	80	11	patient	patient	NOUN
gra-845	80	12	be	be	AUX
gra-845	80	13	diagnosed	diagnose	VERB
gra-845	80	14	as	as	ADP
gra-845	80	15	a	a	DET
gra-845	80	16	case	case	NOUN
gra-845	80	17	of	of	ADP
gra-845	80	18	valproate	valproate	ADJ
gra-845	80	19	toxicity	toxicity	NOUN
gra-845	80	20	.	.	PUNCT
gra-845	81	1	dosage	dosage	NOUN
gra-845	81	2	of	of	ADP
gra-845	81	3	valproate	valproate	ADJ
gra-845	81	4	should	should	AUX
gra-845	81	5	be	be	AUX
gra-845	81	6	appropriate	appropriate	ADJ
gra-845	81	7	to	to	ADP
gra-845	81	8	age	age	NOUN
gra-845	81	9	,	,	PUNCT
gra-845	81	10	condition	condition	NOUN
gra-845	81	11	and	and	CCONJ
gra-845	81	12	other	other	ADJ
gra-845	81	13	factors	factor	NOUN
gra-845	81	14	.	.	PUNCT
gra-845	82	1	liver	liver	NOUN
gra-845	82	2	function	function	NOUN
gra-845	82	3	tests	test	NOUN
gra-845	82	4	mainly	mainly	ADV
gra-845	82	5	amino	amino	ADJ
gra-845	82	6	-	-	PUNCT
gra-845	82	7	transferase	transferase	NOUN
gra-845	82	8	levels	level	NOUN
gra-845	82	9	should	should	AUX
gra-845	82	10	be	be	AUX
gra-845	82	11	frequently	frequently	ADV
gra-845	82	12	monitored	monitor	VERB
gra-845	82	13	in	in	ADP
gra-845	82	14	all	all	DET
gra-845	82	15	patients	patient	NOUN
gra-845	82	16	.	.	PUNCT
gra-845	83	1	valproate	valproate	ADJ
gra-845	83	2	should	should	AUX
gra-845	83	3	be	be	AUX
gra-845	83	4	avoided	avoid	VERB
gra-845	83	5	in	in	ADP
gra-845	83	6	patients	patient	NOUN
gra-845	83	7	with	with	ADP
gra-845	83	8	known	know	VERB
gra-845	83	9	liver	liver	NOUN
gra-845	83	10	diseases	disease	NOUN
gra-845	83	11	,	,	PUNCT
gra-845	83	12	alcoholism	alcoholism	NOUN
gra-845	83	13	,	,	PUNCT
gra-845	83	14	enzyme	enzyme	NOUN
gra-845	83	15	defect	defect	NOUN
gra-845	83	16	disorders	disorder	NOUN
gra-845	83	17	.	.	PUNCT
gra-845	84	1	according	accord	VERB
gra-845	84	2	to	to	ADP
gra-845	84	3	hy	hy	PROPN
gra-845	84	4	's	's	PART
gra-845	84	5	law	law	NOUN
gra-845	84	6	,	,	PUNCT
gra-845	84	7	patients	patient	NOUN
gra-845	84	8	with	with	ADP
gra-845	84	9	drug	drug	NOUN
gra-845	84	10	induced	induce	VERB
gra-845	84	11	hepato	hepato	NOUN
gra-845	84	12	-	-	PUNCT
gra-845	84	13	toxicity	toxicity	NOUN
gra-845	84	14	,	,	PUNCT
gra-845	84	15	have	have	VERB
gra-845	84	16	10	10	NUM
gra-845	84	17	%	%	NOUN
gra-845	84	18	or	or	CCONJ
gra-845	84	19	more	more	ADJ
gra-845	84	20	chance	chance	NOUN
gra-845	84	21	of	of	ADP
gra-845	84	22	progressing	progress	VERB
gra-845	84	23	towards	towards	ADP
gra-845	84	24	hepatic	hepatic	ADJ
gra-845	84	25	failure	failure	NOUN
gra-845	84	26	may	may	AUX
gra-845	84	27	require	require	VERB
gra-845	84	28	liver	liver	NOUN
gra-845	84	29	transplant	transplant	NOUN
gra-845	84	30	.	.	PUNCT
gra-845	85	1	thus	thus	ADV
gra-845	85	2	,	,	PUNCT
gra-845	85	3	early	early	ADJ
gra-845	85	4	diagnosis	diagnosis	NOUN
gra-845	85	5	may	may	AUX
gra-845	85	6	aid	aid	VERB
gra-845	85	7	in	in	ADP
gra-845	85	8	improving	improve	VERB
gra-845	85	9	prognosis	prognosis	NOUN
gra-845	85	10	.	.	PUNCT
gra-845	86	1	references	reference	NOUN
gra-845	86	2	:	:	PUNCT
gra-845	86	3	1	1	NUM
gra-845	86	4	bethesda	bethesda	NOUN
gra-845	86	5	(	(	PUNCT
gra-845	86	6	md	md	PROPN
gra-845	86	7	):	):	PUNCT
gra-845	86	8	national	national	PROPN
gra-845	86	9	institute	institute	PROPN
gra-845	86	10	of	of	ADP
gra-845	86	11	diabetes	diabetes	NOUN
gra-845	86	12	and	and	CCONJ
gra-845	86	13	digestive	digestive	ADJ
gra-845	86	14	and	and	CCONJ
gra-845	86	15	kidney	kidney	NOUN
gra-845	86	16	diseases	disease	NOUN
gra-845	86	17	;	;	PUNCT
gra-845	86	18	2012	2012	NUM
gra-845	86	19	.livertox	.livertox	NUM
gra-845	86	20	:	:	PUNCT
gra-845	86	21	clinical	clinical	ADJ
gra-845	86	22	and	and	CCONJ
gra-845	86	23	research	research	NOUN
gra-845	86	24	information	information	NOUN
gra-845	86	25	on	on	ADP
gra-845	86	26	druginduced	druginduced	ADJ
gra-845	86	27	liver	liver	NOUN
gra-845	86	28	injury	injury	NOUN
gra-845	86	29	https://www.ncbi.nlm.nih.gov/books/nbk548284/	https://www.ncbi.nlm.nih.gov/books/nbk548284/	PROPN
gra-845	86	30	2	2	NUM
gra-845	86	31	.	.	PROPN
gra-845	86	32	zimmerman	zimmerman	PROPN
gra-845	86	33	hj	hj	PROPN
gra-845	86	34	,	,	PUNCT
gra-845	86	35	ishak	ishak	PROPN
gra-845	86	36	kg	kg	PROPN
gra-845	86	37	.	.	PUNCT
gra-845	87	1	valproate	valproate	ADJ
gra-845	87	2	-	-	PUNCT
gra-845	87	3	induced	induce	VERB
gra-845	87	4	hepatic	hepatic	ADJ
gra-845	87	5	injury	injury	NOUN
gra-845	87	6	:	:	PUNCT
gra-845	87	7	analysis	analysis	NOUN
gra-845	87	8	of	of	ADP
gra-845	87	9	23	23	NUM
gra-845	87	10	fatal	fatal	ADJ
gra-845	87	11	cases	case	NOUN
gra-845	87	12	.	.	PUNCT
gra-845	88	1	hepatology	hepatology	NOUN
gra-845	88	2	1982	1982	NUM
gra-845	88	3	;	;	PUNCT
gra-845	88	4	2	2	NUM
gra-845	88	5	:	:	PUNCT
gra-845	88	6	592	592	NUM
gra-845	88	7	-	-	SYM
gra-845	88	8	597	597	NUM
gra-845	88	9	3	3	NUM
gra-845	88	10	.	.	PUNCT
gra-845	89	1	sherlock	sherlock	PROPN
gra-845	89	2	’s	’s	PART
gra-845	89	3	diseases	disease	NOUN
gra-845	89	4	of	of	ADP
gra-845	89	5	the	the	DET
gra-845	89	6	liver	liver	NOUN
gra-845	89	7	and	and	CCONJ
gra-845	89	8	biliary	biliary	NOUN
gra-845	89	9	system	system	NOUN
gra-845	89	10	chapter	chapter	NOUN
gra-845	89	11	24	24	NUM
gra-845	89	12	:	:	PUNCT
gra-845	89	13	drug	drug	NOUN
gra-845	89	14	induced	induce	VERB
gra-845	89	15	liver	liver	NOUN
gra-845	89	16	injury	injury	NOUN
gra-845	89	17	4	4	NUM
gra-845	89	18	.	.	PUNCT
gra-845	90	1	university	university	PROPN
gra-845	90	2	of	of	ADP
gra-845	90	3	maryland	maryland	PROPN
gra-845	90	4	school	school	PROPN
gra-845	90	5	of	of	ADP
gra-845	90	6	pharmacy	pharmacy	NOUN
gra-845	90	7	;	;	PUNCT
gra-845	90	8	july	july	PROPN
gra-845	90	9	2012	2012	NUM
gra-845	90	10	34	34	NUM
gra-845	90	11	x	x	SYM
gra-845	90	12	gjra	gjra	PROPN
gra-845	90	13	global	global	ADJ
gra-845	90	14	journal	journal	PROPN
gra-845	90	15	for	for	ADP
gra-845	90	16	research	research	NOUN
gra-845	90	17	analysis	analysis	NOUN