BACKGROUND A poison is any substance that is harmful to your body when ingested (eaten), inhaled (breathed), injected, or absorbed through the skin. Poisons have been used for many purposes across the span of human existence, most commonly as [1, 2]weapons, anti-venoms, and medicines . Over the last few decades agricultural pesticides have become a common household item in rural areas of the developing world. Due to their easy availability, pesticides have also become commonly used for intentional self- [3, 4]poisoning . Poisoning is an acute presentation and demands a need for early and aggressive management in Emergency. Early identication and triage helps to guide the needed resuscitation efforts and other management priorities like use of antidotes, supportive measures and psychiatric (5, 6)care if needed . The incidence of poisoning in India is among the highest in the world. It is estimated that more than 50,000 people die every year from toxic exposure. According to the National Poisons Information Centre, New Delhi, analysis of poisoning calls showed that the highest incidence of poisoning was due to household agents (44.1%) followed by drugs (18.8%), agricultural pesticides (12.8%), industrial chemicals (8.9%), animals bites and stings (4.7%), plants (1.7%), unknown (2.9%) and miscellaneous groups (5.6%)(7). Poisoning patients with the evidence of organ failure require admission to the intensive care unit (ICU) for organ support and specic management. There are various clinical entities that can determine the clinical course and outcome in the ICU. Besides the type of poison, delayed presentation and multi- organ failure that require immediately advanced life support . (8, 9)organ can lead to high mortality AIM AND OBJECTIVES: 1. To study sociodemographic prole of patients with poisoning. 2. To study the relationship between sociodemographic variables by nature of poisoning. 3. To determine nature and frequency of poisoning. MATERIALS AND METHOD: This is a cross sectional, Descriptive, Observational, Analytical study which was conducted on 60 patients admitted in medicine ward and intensive care unit with poison case in Geetanjali Medical College and Hospital, Udaipur. The study was conducted from June 2018 to December 2018.Data of patients were collected by detailed case history from patient or the attendant regarding nature of poison ,circumstances of poisoning and time of consumption. All routine investigations was done. Follow-up of the enrolled cases was done to know about the clinical course, complications, treatment received and the outcome and data regarding age, sex, time elapsed after intake; circumstances of poisoning, name of the poisonous substance, chemical type, and duration of hospitalization, severity and outcome were collected in the pre-structured proforma. Informed consent was obtained from all subjects to participate in the study. Patient condentiality was maintained. Inclusion criteria: 1) Inpatients having Organophosphorus poisoning, Aluminium phosphide, Zinc phosphide, chemicals and drugs. 2) Inpatients age more than 18 years. Exclusion criteria: All cases with food poisoning and allergic reactions to drugs. RESULTS: With 60 cases study most common poison is organopho sphorus 31.7% with intentional ingestion 95.0% highest among age group 31-40 years with female predominance 75.0% and most commonly seen in married 78.3% and are housewives 43.3%.majority of patients were educated less ththan 12 class 65% and those who belong to upper middle class 31.7% were highest. Table 1: Age Group Table 2: Sex STUDY OF SOCIO-DEMOGRAPHIC AND CLINICAL PROFILE OF VARIOUS POISONING CASES IN ADULTS AT TERTIARY CENTRE Original Research Paper Dr. Rootik patel Resident, Department of General Medicine, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India General Medicine Background – In this study, we determined data of all poisoning cases admitted in medicine ward and intensive care unit with detailed history about nature of poison, time of consumption and circumstances of poisoning. Method- This is a cross-sectional, Descriptive, Observational, analytical study on the sociodemographic and clinical prole of various poisoning cases in Geetanjali Medical College and Hospital, and Udaipur.60 cases were included in the study. . Results- The patients between ages 31-40 are highly 36.7% exposed to poisonous substance with 75.0% female predominance thwhile 25% male, 78.3% were married, 65% patients had education less than 12 class, 43.3% were housewife, organophosphorus is most common 31.7% and upper middle class patients were highest 31.7%. Conclusion- This study found that organophosphorus was the leading cause of acute poisoning .most common mode was intentional. Majority patients belong to upper middle socioeconomic class with predominance in age 31-40years more common in females who are married and are housewives ABSTRACT KEYWORDS : Organophosphorus, poison VOLUME-9, ISSUE-2, FEBRUARY-2020 • PRINT ISSN No. 2277 - 8160 • DOI : 10.36106/gjra Dr. J. S. Jhala* Associate Professor, Department of General Medicine, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India *Corresponding Author Frequency Percent Age Group (Years) 31-40 22 36.7 21-30 17 28.3 <20 10 16.7 41-50 10 16.7 51-60 1 1.7 Total 60 100.0 Frequency Percent Sex Female 45 75.0 Male 15 25.0 Total 60 100.0 38 X GJRA - GLOBAL JOURNAL FOR RESEARCH ANALYSIS Table 3: Marital status Table 5: Occupation Table 6: Socioeconomic status Table 7: Poisonous substance DISCUSSION: In the current study, it was found that the majority of the patients belonged to 31-40 years age group. However, in contrast to the current study Vaiday et al., (2012) found that majority of the patients were aged in 21-30 years of age group. The study showed female predominance. Contrastingly, in the study of Vaidya et al., (2012) the male patients outnumbered the female patients. In the current study majority of the patients were married. However, according to the study of Reddy et al., (2018) there was not much difference between the married and unmarried patients. In the current study, it was found that the majority of patients belonged to upper middle socio-economic class. In contrast to the current results, Reddy et al. (2018) found that the majority of patients belonged to upper lower socio-economic the current, it was found that the most common poisoning substance was Organophosphorus. Similarly, the study of Vaidya et al., (2012) found the Organophosphorus was the most common type of poisoning substance. CONCLUSION It was found in the current study that Organophosphorus was the leading Cause of acute poisoning. The most common mode of poisoning was intentional. Majority of the patients in the current study belonged to upper middle socio-economic Class which claried the reason of suicidal tendencies among the study population. 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VOLUME-9, ISSUE-2, FEBRUARY-2020 • PRINT ISSN No. 2277 - 8160 • DOI : 10.36106/gjra Frequency Percent Marital status Married 47 78.3 Unmarried 13 21.7 Total 60 100.0 Frequency Percent Occupation Housewife 26 43.3 Student 16 26.7 Farmer 11 18.3 worker 7 11.7 Total 60 100.0 Frequency Percent Socioeconomic status Upper Middle 19 31.7 Lower 18 30.0 Upper Lower 16 26.7 Lower Middle 7 11.7 Total 60 100.0 Frequency Percent Name of poisonous substance celphos poison 18 30.0 organophosphorus 19 31.7 Phenyl 6 10.0 dolo 3 5.0 Insecticide 3 5.0 laxman rekha 3 5.0 alprax 2 3.3 clonotril 2 3.3 crocin 1 1.7 lobivon 1 1.7 metocard xl 1 1.7 prolomet xl 1 1.7 Total 60 100.0 X 39GJRA - GLOBAL JOURNAL FOR RESEARCH ANALYSIS