id	sid	tid	token	lemma	pos
bioscience-271	1	1	highlights	highlight	NOUN
bioscience-271	1	2	in	in	ADP
bioscience-271	1	3	bioscience	bioscience	PROPN
bioscience-271	1	4	issn:2682	issn:2682	PROPN
bioscience-271	1	5	-	-	PUNCT
bioscience-271	1	6	4043	4043	NUM
bioscience-271	1	7	doi:10.36462	doi:10.36462	NOUN
bioscience-271	1	8	/	/	SYM
bioscience-271	1	9	h.biosci.202509	h.biosci.202509	NOUN
bioscience-271	1	10	research	research	NOUN
bioscience-271	1	11	article	article	NOUN
bioscience-271	1	12	open	open	ADJ
bioscience-271	1	13	access	access	NOUN
bioscience-271	1	14	1	1	NUM
bioscience-271	1	15	department	department	NOUN
bioscience-271	1	16	of	of	ADP
bioscience-271	1	17	aquatic	aquatic	ADJ
bioscience-271	1	18	animal	animal	NOUN
bioscience-271	1	19	health	health	NOUN
bioscience-271	1	20	,	,	PUNCT
bioscience-271	1	21	faculty	faculty	NOUN
bioscience-271	1	22	of	of	ADP
bioscience-271	1	23	fishery	fishery	NOUN
bioscience-271	1	24	sciences	sciences	PROPN
bioscience-271	1	25	,	,	PUNCT
bioscience-271	1	26	west	west	PROPN
bioscience-271	1	27	bengal	bengal	PROPN
bioscience-271	1	28	university	university	PROPN
bioscience-271	1	29	of	of	ADP
bioscience-271	1	30	animal	animal	NOUN
bioscience-271	1	31	and	and	CCONJ
bioscience-271	1	32	fishery	fishery	NOUN
bioscience-271	1	33	sciences	sciences	PROPN
bioscience-271	1	34	,	,	PUNCT
bioscience-271	1	35	chakgaria	chakgaria	PROPN
bioscience-271	1	36	,	,	PUNCT
bioscience-271	1	37	kolkata	kolkata	PROPN
bioscience-271	1	38	700094	700094	NUM
bioscience-271	1	39	,	,	PUNCT
bioscience-271	1	40	west	west	PROPN
bioscience-271	1	41	bengal	bengal	PROPN
bioscience-271	1	42	,	,	PUNCT
bioscience-271	1	43	india	india	PROPN
bioscience-271	1	44	.	.	PROPN
bioscience-271	1	45	2	2	NUM
bioscience-271	1	46	nitte	nitte	NOUN
bioscience-271	1	47	-	-	PUNCT
bioscience-271	1	48	gok	gok	PROPN
bioscience-271	1	49	coe	coe	PROPN
bioscience-271	1	50	aquamarin	aquamarin	PROPN
bioscience-271	1	51	,	,	PUNCT
bioscience-271	1	52	nucser	nucser	NOUN
bioscience-271	1	53	,	,	PUNCT
bioscience-271	1	54	nitte	nitte	NOUN
bioscience-271	1	55	(	(	PUNCT
bioscience-271	1	56	deemed	deem	VERB
bioscience-271	1	57	to	to	PART
bioscience-271	1	58	be	be	AUX
bioscience-271	1	59	university	university	NOUN
bioscience-271	1	60	)	)	PUNCT
bioscience-271	1	61	,	,	PUNCT
bioscience-271	1	62	paneer	paneer	NOUN
bioscience-271	1	63	campus	campus	NOUN
bioscience-271	1	64	,	,	PUNCT
bioscience-271	1	65	deralakatte	deralakatte	NOUN
bioscience-271	1	66	,	,	PUNCT
bioscience-271	1	67	mangalore	mangalore	PROPN
bioscience-271	1	68	575018	575018	NUM
bioscience-271	1	69	,	,	PUNCT
bioscience-271	1	70	karnataka	karnataka	PROPN
bioscience-271	1	71	,	,	PUNCT
bioscience-271	1	72	india	india	PROPN
bioscience-271	1	73	.	.	PROPN
bioscience-271	2	1	3	3	NUM
bioscience-271	2	2	state	state	NOUN
bioscience-271	2	3	referral	referral	ADJ
bioscience-271	2	4	laboratory	laboratory	NOUN
bioscience-271	2	5	for	for	ADP
bioscience-271	2	6	aquatic	aquatic	ADJ
bioscience-271	2	7	animal	animal	NOUN
bioscience-271	2	8	health	health	NOUN
bioscience-271	2	9	,	,	PUNCT
bioscience-271	2	10	tamil	tamil	PROPN
bioscience-271	2	11	nadu	nadu	PROPN
bioscience-271	2	12	dr	dr	PROPN
bioscience-271	2	13	j.jayalalithaa	j.jayalalithaa	PROPN
bioscience-271	2	14	fisheries	fisheries	PROPN
bioscience-271	2	15	university	university	PROPN
bioscience-271	2	16	,	,	PUNCT
bioscience-271	2	17	madhavaram	madhavaram	VERB
bioscience-271	2	18	milk	milk	NOUN
bioscience-271	2	19	colony	colony	NOUN
bioscience-271	2	20	,	,	PUNCT
bioscience-271	2	21	chennai	chennai	PROPN
bioscience-271	2	22	600051	600051	NUM
bioscience-271	2	23	,	,	PUNCT
bioscience-271	2	24	tamil	tamil	PROPN
bioscience-271	2	25	nadu	nadu	PROPN
bioscience-271	2	26	,	,	PUNCT
bioscience-271	2	27	india	india	PROPN
bioscience-271	2	28	.	.	PROPN
bioscience-271	2	29	4	4	NUM
bioscience-271	2	30	aquatic	aquatic	ADJ
bioscience-271	2	31	animal	animal	NOUN
bioscience-271	2	32	health	health	NOUN
bioscience-271	2	33	and	and	CCONJ
bioscience-271	2	34	environment	environment	NOUN
bioscience-271	2	35	division	division	NOUN
bioscience-271	2	36	,	,	PUNCT
bioscience-271	2	37	icar	icar	ADJ
bioscience-271	2	38	-	-	PUNCT
bioscience-271	2	39	central	central	ADJ
bioscience-271	2	40	institute	institute	NOUN
bioscience-271	2	41	of	of	ADP
bioscience-271	2	42	brackishwater	brackishwater	PROPN
bioscience-271	2	43	aquaculture	aquaculture	NOUN
bioscience-271	2	44	,	,	PUNCT
bioscience-271	2	45	raja	raja	PROPN
bioscience-271	2	46	annamalai	annamalai	PROPN
bioscience-271	2	47	puram	puram	PROPN
bioscience-271	2	48	,	,	PUNCT
bioscience-271	2	49	chennai	chennai	PROPN
bioscience-271	2	50	600028	600028	NUM
bioscience-271	2	51	,	,	PUNCT
bioscience-271	2	52	tamil	tamil	PROPN
bioscience-271	2	53	nadu	nadu	PROPN
bioscience-271	2	54	,	,	PUNCT
bioscience-271	2	55	india	india	PROPN
bioscience-271	2	56	.	.	PUNCT
bioscience-271	3	1	*	*	PUNCT
bioscience-271	3	2	to	to	PART
bioscience-271	3	3	whom	whom	PRON
bioscience-271	3	4	correspondence	correspondence	NOUN
bioscience-271	3	5	should	should	AUX
bioscience-271	3	6	be	be	AUX
bioscience-271	3	7	addressed	address	VERB
bioscience-271	3	8	:	:	PUNCT
bioscience-271	3	9	abrahamtj1@gmail.com	abrahamtj1@gmail.com	X
bioscience-271	3	10	editor	editor	NOUN
bioscience-271	3	11	:	:	PUNCT
bioscience-271	3	12	alsamman	alsamman	PROPN
bioscience-271	3	13	m.	m.	PROPN
bioscience-271	3	14	alsamman	alsamman	PROPN
bioscience-271	3	15	,	,	PUNCT
bioscience-271	3	16	international	international	ADJ
bioscience-271	3	17	center	center	NOUN
bioscience-271	3	18	for	for	ADP
bioscience-271	3	19	agricultural	agricultural	ADJ
bioscience-271	3	20	research	research	NOUN
bioscience-271	3	21	in	in	ADP
bioscience-271	3	22	the	the	DET
bioscience-271	3	23	dry	dry	ADJ
bioscience-271	3	24	areas	area	NOUN
bioscience-271	3	25	(	(	PUNCT
bioscience-271	3	26	icarda	icarda	NOUN
bioscience-271	3	27	)	)	PUNCT
bioscience-271	3	28	,	,	PUNCT
bioscience-271	3	29	cairo	cairo	PROPN
bioscience-271	3	30	,	,	PUNCT
bioscience-271	3	31	egypt	egypt	PROPN
bioscience-271	3	32	.	.	PUNCT
bioscience-271	4	1	reviewer(s	reviewer(s	NOUN
bioscience-271	4	2	):	):	PUNCT
bioscience-271	4	3	hayder	hayder	NOUN
bioscience-271	4	4	tawfeeq	tawfeeq	PROPN
bioscience-271	4	5	qaddoori	qaddoori	PROPN
bioscience-271	4	6	,	,	PUNCT
bioscience-271	4	7	middle	middle	PROPN
bioscience-271	4	8	technical	technical	ADJ
bioscience-271	4	9	univarsity	univarsity	NOUN
bioscience-271	4	10	,	,	PUNCT
bioscience-271	4	11	technical	technical	PROPN
bioscience-271	4	12	insitute	insitute	NOUN
bioscience-271	4	13	of	of	ADP
bioscience-271	4	14	baqubah	baqubah	NOUN
bioscience-271	4	15	,	,	PUNCT
bioscience-271	4	16	department	department	NOUN
bioscience-271	4	17	of	of	ADP
bioscience-271	4	18	nursing	nursing	NOUN
bioscience-271	4	19	,	,	PUNCT
bioscience-271	4	20	dayala	dayala	PROPN
bioscience-271	4	21	iraq	iraq	PROPN
bioscience-271	4	22	.	.	PUNCT
bioscience-271	5	1	abdulaziz	abdulaziz	PROPN
bioscience-271	5	2	ascandari	ascandari	PROPN
bioscience-271	5	3	,	,	PUNCT
bioscience-271	5	4	african	african	ADJ
bioscience-271	5	5	genome	genome	NOUN
bioscience-271	5	6	center	center	NOUN
bioscience-271	5	7	,	,	PUNCT
bioscience-271	5	8	mohammed	mohammed	PROPN
bioscience-271	5	9	vi	vi	PROPN
bioscience-271	5	10	polytechnic	polytechnic	PROPN
bioscience-271	5	11	university	university	PROPN
bioscience-271	5	12	,	,	PUNCT
bioscience-271	5	13	ben	ben	PROPN
bioscience-271	5	14	guerir	guerir	PROPN
bioscience-271	5	15	,	,	PUNCT
bioscience-271	5	16	morocco	morocco	PROPN
bioscience-271	5	17	.	.	PUNCT
bioscience-271	5	18	received	receive	VERB
bioscience-271	5	19	:	:	PUNCT
bioscience-271	5	20	july	july	PROPN
bioscience-271	5	21	26	26	NUM
bioscience-271	5	22	,	,	PUNCT
bioscience-271	5	23	2025	2025	NUM
bioscience-271	5	24	accepted	accept	VERB
bioscience-271	5	25	:	:	PUNCT
bioscience-271	5	26	september	september	PROPN
bioscience-271	5	27	29	29	NUM
bioscience-271	5	28	,	,	PUNCT
bioscience-271	5	29	2025	2025	NUM
bioscience-271	5	30	published	publish	VERB
bioscience-271	5	31	:	:	PUNCT
bioscience-271	5	32	october	october	PROPN
bioscience-271	5	33	18	18	NUM
bioscience-271	5	34	,	,	PUNCT
bioscience-271	5	35	2025	2025	NUM
bioscience-271	5	36	citation	citation	NOUN
bioscience-271	5	37	:	:	PUNCT
bioscience-271	5	38	sinha	sinha	PROPN
bioscience-271	5	39	p	p	PROPN
bioscience-271	5	40	,	,	PUNCT
bioscience-271	5	41	abraham	abraham	PROPN
bioscience-271	5	42	tj	tj	PROPN
bioscience-271	5	43	,	,	PUNCT
bioscience-271	5	44	sen	sen	PROPN
bioscience-271	5	45	a	a	PROPN
bioscience-271	5	46	,	,	PUNCT
bioscience-271	5	47	sharon	sharon	PROPN
bioscience-271	5	48	j	j	PROPN
bioscience-271	5	49	,	,	PUNCT
bioscience-271	5	50	das	das	PROPN
bioscience-271	5	51	r	r	PROPN
bioscience-271	5	52	,	,	PUNCT
bioscience-271	5	53	rajeshwar	rajeshwar	NOUN
bioscience-271	5	54	bn	bn	PROPN
bioscience-271	5	55	,	,	PUNCT
bioscience-271	5	56	uma	uma	PROPN
bioscience-271	5	57	a	a	X
bioscience-271	5	58	,	,	PUNCT
bioscience-271	5	59	patil	patil	PROPN
bioscience-271	5	60	pk	pk	PROPN
bioscience-271	5	61	.	.	PROPN
bioscience-271	5	62	influence	influence	NOUN
bioscience-271	5	63	of	of	ADP
bioscience-271	5	64	in	in	ADP
bioscience-271	5	65	-	-	PUNCT
bioscience-271	5	66	feed	feed	NOUN
bioscience-271	5	67	oxolinic	oxolinic	ADJ
bioscience-271	5	68	acid	acid	NOUN
bioscience-271	5	69	therapy	therapy	NOUN
bioscience-271	5	70	on	on	ADP
bioscience-271	5	71	the	the	DET
bioscience-271	5	72	brain	brain	NOUN
bioscience-271	5	73	histoarchitecture	histoarchitecture	NOUN
bioscience-271	5	74	and	and	CCONJ
bioscience-271	5	75	virulence	virulence	NOUN
bioscience-271	5	76	factors	factor	NOUN
bioscience-271	5	77	of	of	ADP
bioscience-271	5	78	streptococcus	streptococcus	NOUN
bioscience-271	5	79	agalactiae	agalactiae	PROPN
bioscience-271	5	80	infecting	infect	VERB
bioscience-271	5	81	nile	nile	PROPN
bioscience-271	5	82	tilapia	tilapia	PROPN
bioscience-271	5	83	oreochromis	oreochromis	PROPN
bioscience-271	5	84	niloticus	niloticus	PROPN
bioscience-271	5	85	.	.	PUNCT
bioscience-271	6	1	2025	2025	NUM
bioscience-271	6	2	oct	oct	PROPN
bioscience-271	6	3	.	.	PROPN
bioscience-271	6	4	18;8	18;8	NUM
bioscience-271	6	5	:	:	PUNCT
bioscience-271	6	6	bs202509	bs202509	NOUN
bioscience-271	6	7	copyright	copyright	NOUN
bioscience-271	6	8	:	:	PUNCT
bioscience-271	7	1	©	©	PROPN
bioscience-271	7	2	2025	2025	NUM
bioscience-271	7	3	sinha	sinha	NOUN
bioscience-271	7	4	p	p	PROPN
bioscience-271	7	5	et	et	PROPN
bioscience-271	7	6	al	al	PROPN
bioscience-271	7	7	..	..	PROPN
bioscience-271	8	1	this	this	PRON
bioscience-271	8	2	is	be	AUX
bioscience-271	8	3	an	an	DET
bioscience-271	8	4	open	open	ADJ
bioscience-271	8	5	access	access	NOUN
bioscience-271	8	6	article	article	NOUN
bioscience-271	8	7	distributed	distribute	VERB
bioscience-271	8	8	under	under	ADP
bioscience-271	8	9	the	the	DET
bioscience-271	8	10	terms	term	NOUN
bioscience-271	8	11	of	of	ADP
bioscience-271	8	12	the	the	DET
bioscience-271	8	13	creative	creative	ADJ
bioscience-271	8	14	commons	common	NOUN
bioscience-271	8	15	attribution	attribution	NOUN
bioscience-271	8	16	license	license	NOUN
bioscience-271	8	17	,	,	PUNCT
bioscience-271	8	18	which	which	PRON
bioscience-271	8	19	permits	permit	VERB
bioscience-271	8	20	unrestricted	unrestricted	ADJ
bioscience-271	8	21	use	use	NOUN
bioscience-271	8	22	,	,	PUNCT
bioscience-271	8	23	distribution	distribution	NOUN
bioscience-271	8	24	,	,	PUNCT
bioscience-271	8	25	and	and	CCONJ
bioscience-271	8	26	reproduction	reproduction	NOUN
bioscience-271	8	27	in	in	ADP
bioscience-271	8	28	any	any	DET
bioscience-271	8	29	medium	medium	NOUN
bioscience-271	8	30	,	,	PUNCT
bioscience-271	8	31	provided	provide	VERB
bioscience-271	8	32	the	the	DET
bioscience-271	8	33	original	original	ADJ
bioscience-271	8	34	author	author	NOUN
bioscience-271	8	35	and	and	CCONJ
bioscience-271	8	36	source	source	NOUN
bioscience-271	8	37	are	be	AUX
bioscience-271	8	38	credited	credit	VERB
bioscience-271	8	39	.	.	PUNCT
bioscience-271	9	1	influence	influence	NOUN
bioscience-271	9	2	of	of	ADP
bioscience-271	9	3	in	in	ADP
bioscience-271	9	4	-	-	PUNCT
bioscience-271	9	5	feed	feed	NOUN
bioscience-271	9	6	oxolinic	oxolinic	ADJ
bioscience-271	9	7	acid	acid	NOUN
bioscience-271	9	8	therapy	therapy	NOUN
bioscience-271	9	9	on	on	ADP
bioscience-271	9	10	the	the	DET
bioscience-271	9	11	brain	brain	NOUN
bioscience-271	9	12	histoarchitecture	histoarchitecture	NOUN
bioscience-271	9	13	and	and	CCONJ
bioscience-271	9	14	virulence	virulence	NOUN
bioscience-271	9	15	factors	factor	NOUN
bioscience-271	9	16	of	of	ADP
bioscience-271	9	17	streptococcus	streptococcus	NOUN
bioscience-271	9	18	agalactiae	agalactiae	PROPN
bioscience-271	9	19	infecting	infect	VERB
bioscience-271	9	20	nile	nile	PROPN
bioscience-271	9	21	tilapia	tilapia	PROPN
bioscience-271	9	22	oreochromis	oreochromis	PROPN
bioscience-271	9	23	niloticus	niloticus	PROPN
bioscience-271	9	24	priyanka	priyanka	PROPN
bioscience-271	9	25	sinha1	sinha1	PROPN
bioscience-271	9	26	>	>	X
bioscience-271	9	27	<	<	X
bioscience-271	9	28	�	�	PROPN
bioscience-271	9	29	,	,	PUNCT
bioscience-271	9	30	thangapalam	thangapalam	PROPN
bioscience-271	9	31	jawahar	jawahar	PROPN
bioscience-271	9	32	abraham*1	abraham*1	PROPN
bioscience-271	9	33	>	>	X
bioscience-271	9	34	<	<	X
bioscience-271	9	35	�	�	PROPN
bioscience-271	9	36	,	,	PUNCT
bioscience-271	9	37	arya	arya	PROPN
bioscience-271	9	38	sen1	sen1	PROPN
bioscience-271	9	39	>	>	PUNCT
bioscience-271	9	40	<	<	X
bioscience-271	9	41	�	�	PROPN
bioscience-271	9	42	,	,	PUNCT
bioscience-271	9	43	joshi	joshi	PROPN
bioscience-271	9	44	sharon1	sharon1	PROPN
bioscience-271	9	45	>	>	X
bioscience-271	9	46	<	<	X
bioscience-271	9	47	�	�	PROPN
bioscience-271	9	48	,	,	PUNCT
bioscience-271	9	49	ratnapriya	ratnapriya	NOUN
bioscience-271	9	50	das1	das1	NOUN
bioscience-271	9	51	>	>	ADP
bioscience-271	9	52	<	<	X
bioscience-271	9	53	�	�	PROPN
bioscience-271	9	54	,	,	PUNCT
bioscience-271	9	55	b.	b.	PROPN
bioscience-271	9	56	naveen	naveen	PROPN
bioscience-271	9	57	rajeshwar2	rajeshwar2	X
bioscience-271	10	1	>	>	PUNCT
bioscience-271	10	2	<	<	X
bioscience-271	10	3	�	�	PROPN
bioscience-271	10	4	,	,	PUNCT
bioscience-271	10	5	arumugam	arumugam	ADJ
bioscience-271	10	6	uma3	uma3	NOUN
bioscience-271	10	7	>	>	X
bioscience-271	10	8	<	<	X
bioscience-271	10	9	�	�	PROPN
bioscience-271	10	10	,	,	PUNCT
bioscience-271	10	11	prasanna	prasanna	PROPN
bioscience-271	10	12	kumar	kumar	PROPN
bioscience-271	10	13	patil4	patil4	PROPN
bioscience-271	10	14	>	>	PUNCT
bioscience-271	10	15	<	<	X
bioscience-271	10	16	�	�	PROPN
bioscience-271	10	17	abstract	abstract	ADJ
bioscience-271	10	18	streptococcosis	streptococcosis	NOUN
bioscience-271	10	19	and	and	CCONJ
bioscience-271	10	20	its	its	PRON
bioscience-271	10	21	management	management	NOUN
bioscience-271	10	22	are	be	AUX
bioscience-271	10	23	major	major	ADJ
bioscience-271	10	24	constraints	constraint	NOUN
bioscience-271	10	25	to	to	ADP
bioscience-271	10	26	tilapia	tilapia	NOUN
bioscience-271	10	27	aquaculture	aquaculture	NOUN
bioscience-271	10	28	.	.	PUNCT
bioscience-271	11	1	the	the	DET
bioscience-271	11	2	present	present	ADJ
bioscience-271	11	3	study	study	NOUN
bioscience-271	11	4	assessed	assess	VERB
bioscience-271	11	5	the	the	DET
bioscience-271	11	6	effect	effect	NOUN
bioscience-271	11	7	of	of	ADP
bioscience-271	11	8	oral	oral	ADJ
bioscience-271	11	9	administration	administration	NOUN
bioscience-271	11	10	of	of	ADP
bioscience-271	11	11	12	12	NUM
bioscience-271	11	12	mg	mg	PROPN
bioscience-271	11	13	oxolinic	oxolinic	ADJ
bioscience-271	11	14	acid	acid	NOUN
bioscience-271	11	15	(	(	PUNCT
bioscience-271	11	16	oa)/kg	oa)/kg	ADP
bioscience-271	11	17	fish	fish	NOUN
bioscience-271	11	18	/	/	SYM
bioscience-271	11	19	day	day	NOUN
bioscience-271	11	20	for	for	ADP
bioscience-271	11	21	7	7	NUM
bioscience-271	11	22	uninterrupted	uninterrupted	ADJ
bioscience-271	11	23	days	day	NOUN
bioscience-271	11	24	against	against	ADP
bioscience-271	11	25	streptococcus	streptococcus	NOUN
bioscience-271	11	26	agalactiae	agalactiae	PROPN
bioscience-271	11	27	lcr1	lcr1	PROPN
bioscience-271	11	28	(	(	PUNCT
bioscience-271	11	29	sa	sa	NOUN
bioscience-271	11	30	)	)	PUNCT
bioscience-271	11	31	infection	infection	NOUN
bioscience-271	11	32	and	and	CCONJ
bioscience-271	11	33	its	its	PRON
bioscience-271	11	34	influence	influence	NOUN
bioscience-271	11	35	on	on	ADP
bioscience-271	11	36	histopathological	histopathological	ADJ
bioscience-271	11	37	anomalies	anomaly	NOUN
bioscience-271	11	38	in	in	ADP
bioscience-271	11	39	the	the	DET
bioscience-271	11	40	forebrain	forebrain	NOUN
bioscience-271	11	41	,	,	PUNCT
bioscience-271	11	42	optic	optic	ADJ
bioscience-271	11	43	tectum	tectum	ADJ
bioscience-271	11	44	region	region	NOUN
bioscience-271	11	45	of	of	ADP
bioscience-271	11	46	the	the	DET
bioscience-271	11	47	mid	mid	NOUN
bioscience-271	11	48	-	-	NOUN
bioscience-271	11	49	brain	brain	ADJ
bioscience-271	11	50	and	and	CCONJ
bioscience-271	11	51	granular	granular	ADJ
bioscience-271	11	52	cell	cell	NOUN
bioscience-271	11	53	layer	layer	NOUN
bioscience-271	11	54	of	of	ADP
bioscience-271	11	55	the	the	DET
bioscience-271	11	56	cerebellum	cerebellum	NOUN
bioscience-271	11	57	of	of	ADP
bioscience-271	11	58	oreochromis	oreochromis	PROPN
bioscience-271	11	59	niloticus	niloticus	PROPN
bioscience-271	11	60	.	.	PUNCT
bioscience-271	12	1	besides	besides	SCONJ
bioscience-271	12	2	,	,	PUNCT
bioscience-271	12	3	attempts	attempt	NOUN
bioscience-271	12	4	were	be	AUX
bioscience-271	12	5	made	make	VERB
bioscience-271	12	6	to	to	PART
bioscience-271	12	7	understand	understand	VERB
bioscience-271	12	8	how	how	SCONJ
bioscience-271	12	9	the	the	DET
bioscience-271	12	10	oa	oa	PROPN
bioscience-271	12	11	impacts	impact	VERB
bioscience-271	12	12	the	the	DET
bioscience-271	12	13	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	12	14	and	and	CCONJ
bioscience-271	12	15	camp	camp	NOUN
bioscience-271	12	16	factor	factor	NOUN
bioscience-271	12	17	of	of	ADP
bioscience-271	12	18	s.	s.	PROPN
bioscience-271	12	19	agalactiae	agalactiae	PROPN
bioscience-271	12	20	through	through	ADP
bioscience-271	12	21	molecular	molecular	ADJ
bioscience-271	12	22	docking	docking	NOUN
bioscience-271	12	23	.	.	PUNCT
bioscience-271	13	1	the	the	DET
bioscience-271	13	2	ld50	ld50	PROPN
bioscience-271	13	3	of	of	ADP
bioscience-271	13	4	sa	sa	PROPN
bioscience-271	13	5	was	be	AUX
bioscience-271	13	6	1.26	1.26	NUM
bioscience-271	13	7	×	×	NOUN
bioscience-271	13	8	108	108	NUM
bioscience-271	13	9	cells	cell	NOUN
bioscience-271	13	10	/	/	SYM
bioscience-271	13	11	fish	fish	NOUN
bioscience-271	13	12	.	.	PUNCT
bioscience-271	14	1	sa	sa	PROPN
bioscience-271	14	2	infection	infection	NOUN
bioscience-271	14	3	was	be	AUX
bioscience-271	14	4	apparent	apparent	ADJ
bioscience-271	14	5	in	in	ADP
bioscience-271	14	6	oa	oa	ADV
bioscience-271	14	7	-	-	PUNCT
bioscience-271	14	8	treated	treat	VERB
bioscience-271	14	9	and	and	CCONJ
bioscience-271	14	10	untreated	untreated	ADJ
bioscience-271	14	11	groups	group	NOUN
bioscience-271	14	12	,	,	PUNCT
bioscience-271	14	13	and	and	CCONJ
bioscience-271	14	14	the	the	DET
bioscience-271	14	15	brain	brain	NOUN
bioscience-271	14	16	tissues	tissue	NOUN
bioscience-271	14	17	exhibited	exhibit	VERB
bioscience-271	14	18	the	the	DET
bioscience-271	14	19	progression	progression	NOUN
bioscience-271	14	20	and	and	CCONJ
bioscience-271	14	21	reversal	reversal	NOUN
bioscience-271	14	22	of	of	ADP
bioscience-271	14	23	meningitis	meningitis	NOUN
bioscience-271	14	24	.	.	PUNCT
bioscience-271	15	1	the	the	DET
bioscience-271	15	2	forebrain	forebrain	NOUN
bioscience-271	15	3	exhibited	exhibit	VERB
bioscience-271	15	4	thickening	thickening	NOUN
bioscience-271	15	5	of	of	ADP
bioscience-271	15	6	the	the	DET
bioscience-271	15	7	meninx	meninx	PROPN
bioscience-271	15	8	primitiva	primitiva	PROPN
bioscience-271	15	9	,	,	PUNCT
bioscience-271	15	10	vacuolation	vacuolation	NOUN
bioscience-271	15	11	,	,	PUNCT
bioscience-271	15	12	and	and	CCONJ
bioscience-271	15	13	degeneration	degeneration	NOUN
bioscience-271	15	14	in	in	ADP
bioscience-271	15	15	the	the	DET
bioscience-271	15	16	brain	brain	NOUN
bioscience-271	15	17	parenchyma	parenchyma	NOUN
bioscience-271	15	18	and	and	CCONJ
bioscience-271	15	19	meninx	meninx	PROPN
bioscience-271	15	20	primitiva	primitiva	PROPN
bioscience-271	15	21	.	.	PUNCT
bioscience-271	16	1	inflammatory	inflammatory	ADJ
bioscience-271	16	2	changes	change	NOUN
bioscience-271	16	3	such	such	ADJ
bioscience-271	16	4	as	as	ADP
bioscience-271	16	5	meningitis	meningitis	NOUN
bioscience-271	16	6	and	and	CCONJ
bioscience-271	16	7	mononuclear	mononuclear	ADJ
bioscience-271	16	8	cell	cell	NOUN
bioscience-271	16	9	infiltration	infiltration	NOUN
bioscience-271	16	10	were	be	AUX
bioscience-271	16	11	documented	document	VERB
bioscience-271	16	12	.	.	PUNCT
bioscience-271	17	1	the	the	DET
bioscience-271	17	2	midbrain	midbrain	NOUN
bioscience-271	17	3	had	have	VERB
bioscience-271	17	4	edematous	edematous	ADJ
bioscience-271	17	5	optic	optic	ADJ
bioscience-271	17	6	tectum	tectum	NOUN
bioscience-271	17	7	,	,	PUNCT
bioscience-271	17	8	loosening	loosening	NOUN
bioscience-271	17	9	of	of	ADP
bioscience-271	17	10	connective	connective	ADJ
bioscience-271	17	11	tissue	tissue	NOUN
bioscience-271	17	12	,	,	PUNCT
bioscience-271	17	13	and	and	CCONJ
bioscience-271	17	14	leukocyte	leukocyte	NOUN
bioscience-271	17	15	infiltration	infiltration	NOUN
bioscience-271	17	16	.	.	PUNCT
bioscience-271	18	1	in	in	ADP
bioscience-271	18	2	the	the	DET
bioscience-271	18	3	granular	granular	ADJ
bioscience-271	18	4	cell	cell	NOUN
bioscience-271	18	5	layer	layer	NOUN
bioscience-271	18	6	,	,	PUNCT
bioscience-271	18	7	cerebellum	cerebellum	NOUN
bioscience-271	18	8	changes	change	NOUN
bioscience-271	18	9	such	such	ADJ
bioscience-271	18	10	as	as	ADP
bioscience-271	18	11	spongiform	spongiform	NOUN
bioscience-271	18	12	encephalopathy	encephalopathy	ADJ
bioscience-271	18	13	and	and	CCONJ
bioscience-271	18	14	necrosis	necrosis	NOUN
bioscience-271	18	15	indicate	indicate	VERB
bioscience-271	18	16	region	region	NOUN
bioscience-271	18	17	-	-	PUNCT
bioscience-271	18	18	specific	specific	ADJ
bioscience-271	18	19	damage	damage	NOUN
bioscience-271	18	20	.	.	PUNCT
bioscience-271	19	1	however	however	ADV
bioscience-271	19	2	,	,	PUNCT
bioscience-271	19	3	the	the	DET
bioscience-271	19	4	oa	oa	NOUN
bioscience-271	19	5	effectively	effectively	ADV
bioscience-271	19	6	reduced	reduce	VERB
bioscience-271	19	7	the	the	DET
bioscience-271	19	8	severity	severity	NOUN
bioscience-271	19	9	of	of	ADP
bioscience-271	19	10	brain	brain	NOUN
bioscience-271	19	11	tissue	tissue	NOUN
bioscience-271	19	12	damage	damage	NOUN
bioscience-271	19	13	,	,	PUNCT
bioscience-271	19	14	possibly	possibly	ADV
bioscience-271	19	15	by	by	ADP
bioscience-271	19	16	its	its	PRON
bioscience-271	19	17	binding	bind	VERB
bioscience-271	19	18	affinities	affinity	NOUN
bioscience-271	19	19	and	and	CCONJ
bioscience-271	19	20	upsetting	upset	VERB
bioscience-271	19	21	the	the	DET
bioscience-271	19	22	activities	activity	NOUN
bioscience-271	19	23	of	of	ADP
bioscience-271	19	24	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	19	25	and	and	CCONJ
bioscience-271	19	26	camp	camp	NOUN
bioscience-271	19	27	factor	factor	NOUN
bioscience-271	19	28	,	,	PUNCT
bioscience-271	19	29	as	as	SCONJ
bioscience-271	19	30	confirmed	confirm	VERB
bioscience-271	19	31	by	by	ADP
bioscience-271	19	32	molecular	molecular	ADJ
bioscience-271	19	33	docking	docking	NOUN
bioscience-271	19	34	.	.	PUNCT
bioscience-271	20	1	these	these	DET
bioscience-271	20	2	results	result	NOUN
bioscience-271	20	3	confirmed	confirm	VERB
bioscience-271	20	4	that	that	SCONJ
bioscience-271	20	5	oa	oa	PROPN
bioscience-271	20	6	can	can	AUX
bioscience-271	20	7	cross	cross	VERB
bioscience-271	20	8	the	the	DET
bioscience-271	20	9	blood	blood	NOUN
bioscience-271	20	10	-	-	PUNCT
bioscience-271	20	11	brain	brain	NOUN
bioscience-271	20	12	barrier	barrier	NOUN
bioscience-271	20	13	and	and	CCONJ
bioscience-271	20	14	interact	interact	VERB
bioscience-271	20	15	with	with	ADP
bioscience-271	20	16	virulence	virulence	NOUN
bioscience-271	20	17	proteins	protein	NOUN
bioscience-271	20	18	to	to	PART
bioscience-271	20	19	reduce	reduce	VERB
bioscience-271	20	20	the	the	DET
bioscience-271	20	21	sa	sa	NOUN
bioscience-271	20	22	infection	infection	NOUN
bioscience-271	20	23	in	in	ADP
bioscience-271	20	24	the	the	DET
bioscience-271	20	25	brain	brain	NOUN
bioscience-271	20	26	.	.	PUNCT
bioscience-271	21	1	furthermore	furthermore	ADV
bioscience-271	21	2	,	,	PUNCT
bioscience-271	21	3	the	the	DET
bioscience-271	21	4	results	result	NOUN
bioscience-271	21	5	underscore	underscore	VERB
bioscience-271	21	6	its	its	PRON
bioscience-271	21	7	responsible	responsible	ADJ
bioscience-271	21	8	use	use	NOUN
bioscience-271	21	9	in	in	ADP
bioscience-271	21	10	aquaculture	aquaculture	NOUN
bioscience-271	21	11	,	,	PUNCT
bioscience-271	21	12	as	as	SCONJ
bioscience-271	21	13	oa	oa	PROPN
bioscience-271	21	14	is	be	AUX
bioscience-271	21	15	a	a	DET
bioscience-271	21	16	critically	critically	ADV
bioscience-271	21	17	important	important	ADJ
bioscience-271	21	18	human	human	ADJ
bioscience-271	21	19	medicine	medicine	NOUN
bioscience-271	21	20	and	and	CCONJ
bioscience-271	21	21	ought	ought	AUX
bioscience-271	21	22	to	to	PART
bioscience-271	21	23	be	be	AUX
bioscience-271	21	24	used	use	VERB
bioscience-271	21	25	as	as	ADP
bioscience-271	21	26	a	a	DET
bioscience-271	21	27	secondary	secondary	ADJ
bioscience-271	21	28	treatment	treatment	NOUN
bioscience-271	21	29	.	.	PUNCT
bioscience-271	22	1	keywords	keyword	NOUN
bioscience-271	22	2	:	:	PUNCT
bioscience-271	22	3	aquaculture	aquaculture	NOUN
bioscience-271	22	4	,	,	PUNCT
bioscience-271	22	5	streptococcosis	streptococcosis	NOUN
bioscience-271	22	6	,	,	PUNCT
bioscience-271	22	7	virulence	virulence	NOUN
bioscience-271	22	8	proteins	protein	NOUN
bioscience-271	22	9	,	,	PUNCT
bioscience-271	22	10	antibiotic	antibiotic	ADJ
bioscience-271	22	11	therapy	therapy	NOUN
bioscience-271	22	12	,	,	PUNCT
bioscience-271	22	13	meningitis	meningitis	NOUN
bioscience-271	22	14	,	,	PUNCT
bioscience-271	22	15	histoarchitecture	histoarchitecture	NOUN
bioscience-271	22	16	.	.	PUNCT
bioscience-271	23	1	introduction	introduction	NOUN
bioscience-271	23	2	aquaculture	aquaculture	NOUN
bioscience-271	23	3	is	be	AUX
bioscience-271	23	4	swiftly	swiftly	ADV
bioscience-271	23	5	intensifying	intensify	VERB
bioscience-271	23	6	,	,	PUNCT
bioscience-271	23	7	significantly	significantly	ADV
bioscience-271	23	8	contributing	contribute	VERB
bioscience-271	23	9	to	to	ADP
bioscience-271	23	10	global	global	ADJ
bioscience-271	23	11	food	food	NOUN
bioscience-271	23	12	production	production	NOUN
bioscience-271	23	13	,	,	PUNCT
bioscience-271	23	14	economic	economic	ADJ
bioscience-271	23	15	development	development	NOUN
bioscience-271	23	16	,	,	PUNCT
bioscience-271	23	17	and	and	CCONJ
bioscience-271	23	18	nutritional	nutritional	ADJ
bioscience-271	23	19	security	security	NOUN
bioscience-271	23	20	.	.	PUNCT
bioscience-271	24	1	in	in	ADP
bioscience-271	24	2	2022	2022	NUM
bioscience-271	24	3	,	,	PUNCT
bioscience-271	24	4	aquaculture	aquaculture	NOUN
bioscience-271	24	5	contributed	contribute	VERB
bioscience-271	24	6	about	about	ADV
bioscience-271	24	7	59	59	NUM
bioscience-271	24	8	%	%	NOUN
bioscience-271	24	9	of	of	ADP
bioscience-271	24	10	the	the	DET
bioscience-271	24	11	total	total	ADJ
bioscience-271	24	12	fish	fish	NOUN
bioscience-271	24	13	production	production	NOUN
bioscience-271	24	14	of	of	ADP
bioscience-271	24	15	185.4	185.4	NUM
bioscience-271	24	16	million	million	NUM
bioscience-271	24	17	tonnes	tonne	NOUN
bioscience-271	24	18	.	.	PUNCT
bioscience-271	25	1	cichlids	cichlid	NOUN
bioscience-271	25	2	,	,	PUNCT
bioscience-271	25	3	including	include	VERB
bioscience-271	25	4	tilapias	tilapia	NOUN
bioscience-271	25	5	,	,	PUNCT
bioscience-271	25	6	ranked	rank	VERB
bioscience-271	25	7	third	third	ADV
bioscience-271	25	8	in	in	ADP
bioscience-271	25	9	the	the	DET
bioscience-271	25	10	major	major	ADJ
bioscience-271	25	11	farmed	farm	VERB
bioscience-271	25	12	fish	fish	NOUN
bioscience-271	25	13	group	group	NOUN
bioscience-271	25	14	with	with	ADP
bioscience-271	25	15	a	a	DET
bioscience-271	25	16	contribution	contribution	NOUN
bioscience-271	25	17	of	of	ADP
bioscience-271	25	18	10.6	10.6	NUM
bioscience-271	25	19	%	%	NOUN
bioscience-271	25	20	[	[	X
bioscience-271	25	21	1	1	NUM
bioscience-271	25	22	]	]	PUNCT
bioscience-271	25	23	.	.	PUNCT
bioscience-271	26	1	tilapias	tilapia	NOUN
bioscience-271	26	2	are	be	AUX
bioscience-271	26	3	highly	highly	ADV
bioscience-271	26	4	favourable	favourable	ADJ
bioscience-271	26	5	species	specie	NOUN
bioscience-271	26	6	for	for	ADP
bioscience-271	26	7	aquaculture	aquaculture	NOUN
bioscience-271	26	8	due	due	ADP
bioscience-271	26	9	to	to	ADP
bioscience-271	26	10	their	their	PRON
bioscience-271	26	11	adaptability	adaptability	NOUN
bioscience-271	26	12	,	,	PUNCT
bioscience-271	26	13	rapid	rapid	ADJ
bioscience-271	26	14	growth	growth	NOUN
bioscience-271	26	15	,	,	PUNCT
bioscience-271	26	16	disease	disease	NOUN
bioscience-271	26	17	resistance	resistance	NOUN
bioscience-271	26	18	,	,	PUNCT
bioscience-271	26	19	and	and	CCONJ
bioscience-271	26	20	low	low	ADJ
bioscience-271	26	21	production	production	NOUN
bioscience-271	26	22	costs	cost	NOUN
bioscience-271	26	23	[	[	X
bioscience-271	26	24	2	2	NUM
bioscience-271	26	25	]	]	PUNCT
bioscience-271	26	26	.	.	PUNCT
bioscience-271	27	1	however	however	ADV
bioscience-271	27	2	,	,	PUNCT
bioscience-271	27	3	intensive	intensive	ADJ
bioscience-271	27	4	tilapia	tilapia	NOUN
bioscience-271	27	5	aquaculture	aquaculture	NOUN
bioscience-271	27	6	has	have	AUX
bioscience-271	27	7	led	lead	VERB
bioscience-271	27	8	to	to	ADP
bioscience-271	27	9	a	a	DET
bioscience-271	27	10	rise	rise	NOUN
bioscience-271	27	11	in	in	ADP
bioscience-271	27	12	diseases	disease	NOUN
bioscience-271	27	13	,	,	PUNCT
bioscience-271	27	14	particularly	particularly	ADV
bioscience-271	27	15	bacterial	bacterial	ADJ
bioscience-271	27	16	infections	infection	NOUN
bioscience-271	27	17	like	like	ADP
bioscience-271	27	18	streptococcosis	streptococcosis	NOUN
bioscience-271	27	19	,	,	PUNCT
bioscience-271	27	20	motile	motile	NOUN
bioscience-271	27	21	aeromonas	aeromonas	PROPN
bioscience-271	27	22	septicemia	septicemia	PROPN
bioscience-271	27	23	(	(	PUNCT
bioscience-271	27	24	mas	mas	PROPN
bioscience-271	27	25	)	)	PUNCT
bioscience-271	27	26	,	,	PUNCT
bioscience-271	27	27	vibriosis	vibriosis	NOUN
bioscience-271	27	28	,	,	PUNCT
bioscience-271	27	29	and	and	CCONJ
bioscience-271	27	30	columnaris	columnaris	NOUN
bioscience-271	27	31	,	,	PUNCT
bioscience-271	27	32	which	which	PRON
bioscience-271	27	33	pose	pose	VERB
bioscience-271	27	34	significant	significant	ADJ
bioscience-271	27	35	challenges	challenge	NOUN
bioscience-271	27	36	to	to	ADP
bioscience-271	27	37	farming	farm	VERB
bioscience-271	27	38	[	[	X
bioscience-271	27	39	3	3	NUM
bioscience-271	27	40	]	]	PUNCT
bioscience-271	27	41	.	.	PUNCT
bioscience-271	28	1	streptococcosis	streptococcosis	NOUN
bioscience-271	28	2	,	,	PUNCT
bioscience-271	28	3	caused	cause	VERB
bioscience-271	28	4	by	by	ADP
bioscience-271	28	5	streptococcus	streptococcus	NOUN
bioscience-271	28	6	agalactiae	agalactiae	NOUN
bioscience-271	28	7	(	(	PUNCT
bioscience-271	28	8	sa	sa	PROPN
bioscience-271	28	9	)	)	PUNCT
bioscience-271	28	10	and	and	CCONJ
bioscience-271	28	11	s.	s.	PROPN
bioscience-271	28	12	iniae	iniae	PROPN
bioscience-271	28	13	,	,	PUNCT
bioscience-271	28	14	is	be	AUX
bioscience-271	28	15	one	one	NUM
bioscience-271	28	16	of	of	ADP
bioscience-271	28	17	the	the	DET
bioscience-271	28	18	most	most	ADV
bioscience-271	28	19	important	important	ADJ
bioscience-271	28	20	bacterial	bacterial	ADJ
bioscience-271	28	21	diseases	disease	NOUN
bioscience-271	28	22	in	in	ADP
bioscience-271	28	23	tilapia	tilapia	NOUN
bioscience-271	28	24	aquaculture	aquaculture	NOUN
bioscience-271	28	25	,	,	PUNCT
bioscience-271	28	26	causing	cause	VERB
bioscience-271	28	27	substantial	substantial	ADJ
bioscience-271	28	28	economic	economic	ADJ
bioscience-271	28	29	losses	loss	NOUN
bioscience-271	28	30	globally	globally	ADV
bioscience-271	28	31	[	[	X
bioscience-271	28	32	2	2	NUM
bioscience-271	28	33	;	;	PUNCT
bioscience-271	28	34	4	4	NUM
bioscience-271	28	35	]	]	PUNCT
bioscience-271	28	36	.	.	PUNCT
bioscience-271	29	1	it	it	PRON
bioscience-271	29	2	can	can	AUX
bioscience-271	29	3	lead	lead	VERB
bioscience-271	29	4	to	to	ADP
bioscience-271	29	5	meningoencephalitis	meningoencephalitis	PROPN
bioscience-271	29	6	in	in	ADP
bioscience-271	29	7	tilapia	tilapia	NOUN
bioscience-271	29	8	,	,	PUNCT
bioscience-271	29	9	characterised	characterise	VERB
bioscience-271	29	10	by	by	ADP
bioscience-271	29	11	several	several	ADJ
bioscience-271	29	12	neurological	neurological	ADJ
bioscience-271	29	13	disorders	disorder	NOUN
bioscience-271	29	14	and	and	CCONJ
bioscience-271	29	15	brain	brain	NOUN
bioscience-271	29	16	lesions	lesion	NOUN
bioscience-271	29	17	[	[	X
bioscience-271	29	18	5	5	NUM
bioscience-271	29	19	;	;	PUNCT
bioscience-271	29	20	6	6	NUM
bioscience-271	29	21	;	;	PUNCT
bioscience-271	29	22	7	7	NUM
bioscience-271	29	23	;	;	PUNCT
bioscience-271	29	24	8	8	NUM
bioscience-271	29	25	]	]	PUNCT
bioscience-271	29	26	.	.	PUNCT
bioscience-271	30	1	studies	study	NOUN
bioscience-271	30	2	indicated	indicate	VERB
bioscience-271	30	3	that	that	SCONJ
bioscience-271	30	4	sa	sa	PROPN
bioscience-271	30	5	causes	cause	VERB
bioscience-271	30	6	extensive	extensive	ADJ
bioscience-271	30	7	brain	brain	NOUN
bioscience-271	30	8	damage	damage	NOUN
bioscience-271	30	9	,	,	PUNCT
bioscience-271	30	10	particularly	particularly	ADV
bioscience-271	30	11	in	in	ADP
bioscience-271	30	12	regions	region	NOUN
bioscience-271	30	13	controlling	control	VERB
bioscience-271	30	14	swimming	swimming	NOUN
bioscience-271	30	15	activities	activity	NOUN
bioscience-271	30	16	,	,	PUNCT
bioscience-271	30	17	due	due	ADP
bioscience-271	30	18	to	to	ADP
bioscience-271	30	19	bacterial	bacterial	ADJ
bioscience-271	30	20	invasion	invasion	NOUN
bioscience-271	30	21	and	and	CCONJ
bioscience-271	30	22	acute	acute	ADJ
bioscience-271	30	23	inflammatory	inflammatory	ADJ
bioscience-271	30	24	responses	response	NOUN
bioscience-271	30	25	[	[	X
bioscience-271	30	26	6	6	NUM
bioscience-271	30	27	;	;	PUNCT
bioscience-271	30	28	8	8	NUM
bioscience-271	30	29	;	;	PUNCT
bioscience-271	30	30	9	9	NUM
bioscience-271	30	31	]	]	PUNCT
bioscience-271	30	32	.	.	PUNCT
bioscience-271	31	1	control	control	NOUN
bioscience-271	31	2	measures	measure	NOUN
bioscience-271	31	3	for	for	ADP
bioscience-271	31	4	streptococcosis	streptococcosis	NOUN
bioscience-271	31	5	include	include	VERB
bioscience-271	31	6	proper	proper	ADJ
bioscience-271	31	7	farm	farm	NOUN
bioscience-271	31	8	location	location	NOUN
bioscience-271	31	9	selection	selection	NOUN
bioscience-271	31	10	,	,	PUNCT
bioscience-271	31	11	good	good	ADJ
bioscience-271	31	12	aquaculture	aquaculture	NOUN
bioscience-271	31	13	practices	practice	NOUN
bioscience-271	31	14	,	,	PUNCT
bioscience-271	31	15	antibiotics	antibiotic	NOUN
bioscience-271	31	16	,	,	PUNCT
bioscience-271	31	17	immunostimulants	immunostimulant	NOUN
bioscience-271	31	18	,	,	PUNCT
bioscience-271	31	19	and	and	CCONJ
bioscience-271	31	20	vaccines	vaccine	NOUN
bioscience-271	31	21	[	[	X
bioscience-271	31	22	2	2	NUM
bioscience-271	31	23	]	]	PUNCT
bioscience-271	31	24	.	.	PUNCT
bioscience-271	32	1	antimicrobials	antimicrobial	NOUN
bioscience-271	32	2	like	like	ADP
bioscience-271	32	3	amphenicols	amphenicol	NOUN
bioscience-271	32	4	,	,	PUNCT
bioscience-271	32	5	quinolones	quinolone	NOUN
bioscience-271	32	6	,	,	PUNCT
bioscience-271	32	7	and	and	CCONJ
bioscience-271	32	8	tetracyclines	tetracycline	NOUN
bioscience-271	32	9	are	be	AUX
bioscience-271	32	10	widely	widely	ADV
bioscience-271	32	11	used	use	VERB
bioscience-271	32	12	,	,	PUNCT
bioscience-271	32	13	but	but	CCONJ
bioscience-271	32	14	their	their	PRON
bioscience-271	32	15	use	use	NOUN
bioscience-271	32	16	raises	raise	VERB
bioscience-271	32	17	highlights	highlight	NOUN
bioscience-271	32	18	in	in	ADP
bioscience-271	32	19	bioscience	bioscience	NOUN
bioscience-271	32	20	page	page	NOUN
bioscience-271	32	21	1	1	NUM
bioscience-271	32	22	of	of	ADP
bioscience-271	32	23	10	10	NUM
bioscience-271	32	24	october	october	PROPN
bioscience-271	32	25	2025|volume	2025|volume	NUM
bioscience-271	32	26	8	8	NUM
bioscience-271	32	27	https://doi.org/10.36462/h.biosci.202509	https://doi.org/10.36462/h.biosci.202509	NOUN
bioscience-271	32	28	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
bioscience-271	32	29	mailto:sinhapriyanka1197@gmail.com	mailto:sinhapriyanka1197@gmail.com	PROPN
bioscience-271	32	30	https://orcid.org/0009-0005-1867-5422	https://orcid.org/0009-0005-1867-5422	NOUN
bioscience-271	32	31	mailto:abrahamtj1@gmail.com	mailto:abrahamtj1@gmail.com	PROPN
bioscience-271	32	32	https://orcid.org/0000-0003-0581-1307	https://orcid.org/0000-0003-0581-1307	PROPN
bioscience-271	32	33	mailto:arya.sen2@gmail.com	mailto:arya.sen2@gmail.com	PROPN
bioscience-271	32	34	https://orcid.org/0000-0001-8991-7875	https://orcid.org/0000-0001-8991-7875	PROPN
bioscience-271	32	35	mailto:ashjosh9@gmail.com	mailto:ashjosh9@gmail.com	PROPN
bioscience-271	32	36	https://orcid.org/0009-0009-6799-9473	https://orcid.org/0009-0009-6799-9473	PROPN
bioscience-271	32	37	mailto:ratnapriyadas2015@gmail.com	mailto:ratnapriyadas2015@gmail.com	PROPN
bioscience-271	32	38	https://orcid.org/0000-0002-6414-7840	https://orcid.org/0000-0002-6414-7840	NOUN
bioscience-271	32	39	mailto:naveen.rajeshwar@nitte.edu.in	mailto:naveen.rajeshwar@nitte.edu.in	PROPN
bioscience-271	32	40	https://orcid.org/0000-0002-4496-9492	https://orcid.org/0000-0002-4496-9492	PROPN
bioscience-271	32	41	mailto:uma@tnfu.ac.in	mailto:uma@tnfu.ac.in	ADV
bioscience-271	32	42	https://orcid.org/0000-0002-9429-4075	https://orcid.org/0000-0002-9429-4075	VERB
bioscience-271	32	43	mailto:pk.patil@icar.org.in	mailto:pk.patil@icar.org.in	PROPN
bioscience-271	32	44	https://orcid.org/0000-0002-1924-5863	https://orcid.org/0000-0002-1924-5863	PROPN
bioscience-271	32	45	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	32	46	sinha	sinha	VERB
bioscience-271	32	47	p	p	PROPN
bioscience-271	32	48	et	et	PROPN
bioscience-271	32	49	al	al	PROPN
bioscience-271	32	50	.	.	PROPN
bioscience-271	32	51	,	,	PUNCT
bioscience-271	32	52	2025	2025	NUM
bioscience-271	32	53	effect	effect	NOUN
bioscience-271	32	54	of	of	ADP
bioscience-271	32	55	oxolinic	oxolinic	ADJ
bioscience-271	32	56	acid	acid	NOUN
bioscience-271	32	57	therapy	therapy	NOUN
bioscience-271	32	58	figure	figure	NOUN
bioscience-271	32	59	1	1	NUM
bioscience-271	32	60	.	.	PUNCT
bioscience-271	33	1	the	the	DET
bioscience-271	33	2	histopathological	histopathological	ADJ
bioscience-271	33	3	changes	change	NOUN
bioscience-271	33	4	indicating	indicate	VERB
bioscience-271	33	5	meningitis	meningitis	NOUN
bioscience-271	33	6	(	(	PUNCT
bioscience-271	33	7	*	*	PUNCT
bioscience-271	33	8	)	)	PUNCT
bioscience-271	33	9	in	in	ADP
bioscience-271	33	10	the	the	DET
bioscience-271	33	11	forebrain	forebrain	NOUN
bioscience-271	33	12	of	of	ADP
bioscience-271	33	13	streptococcus	streptococcus	NOUN
bioscience-271	33	14	agalactiae	agalactiae	PROPN
bioscience-271	33	15	lcr1	lcr1	PROPN
bioscience-271	33	16	challenged	challenge	VERB
bioscience-271	33	17	and	and	CCONJ
bioscience-271	33	18	oxolinic	oxolinic	ADJ
bioscience-271	33	19	acid	acid	NOUN
bioscience-271	33	20	(	(	PUNCT
bioscience-271	33	21	oa	oa	INTJ
bioscience-271	33	22	)	)	PUNCT
bioscience-271	33	23	treated	treat	VERB
bioscience-271	33	24	and	and	CCONJ
bioscience-271	33	25	untreated	untreate	VERB
bioscience-271	33	26	oreochromis	oreochromis	PROPN
bioscience-271	33	27	niloticus	niloticus	PROPN
bioscience-271	33	28	juveniles	juvenile	NOUN
bioscience-271	33	29	.	.	PUNCT
bioscience-271	34	1	[	[	X
bioscience-271	34	2	a	a	X
bioscience-271	34	3	]	]	X
bioscience-271	34	4	control	control	NOUN
bioscience-271	34	5	,	,	PUNCT
bioscience-271	34	6	[	[	X
bioscience-271	34	7	b	b	X
bioscience-271	34	8	]	]	X
bioscience-271	34	9	day	day	NOUN
bioscience-271	34	10	post	post	NOUN
bioscience-271	34	11	-	-	NOUN
bioscience-271	34	12	injection	injection	ADJ
bioscience-271	34	13	(	(	PUNCT
bioscience-271	34	14	dpi	dpi	NOUN
bioscience-271	34	15	)	)	PUNCT
bioscience-271	34	16	1	1	NUM
bioscience-271	34	17	oa	oa	PRON
bioscience-271	34	18	treated	treat	VERB
bioscience-271	34	19	and	and	CCONJ
bioscience-271	34	20	[	[	X
bioscience-271	34	21	c	c	X
bioscience-271	34	22	]	]	X
bioscience-271	34	23	untreated	untreated	ADJ
bioscience-271	34	24	;	;	PUNCT
bioscience-271	34	25	[	[	X
bioscience-271	34	26	d	d	X
bioscience-271	34	27	]	]	X
bioscience-271	34	28	dpi	dpi	NOUN
bioscience-271	34	29	7	7	NUM
bioscience-271	34	30	oa	oa	NOUN
bioscience-271	34	31	treated	treat	VERB
bioscience-271	34	32	and	and	CCONJ
bioscience-271	34	33	[	[	X
bioscience-271	34	34	e	e	X
bioscience-271	34	35	]	]	X
bioscience-271	34	36	untreated	untreated	ADJ
bioscience-271	34	37	;	;	PUNCT
bioscience-271	34	38	[	[	X
bioscience-271	34	39	f	f	X
bioscience-271	34	40	]	]	X
bioscience-271	34	41	dpi	dpi	NOUN
bioscience-271	34	42	14	14	NUM
bioscience-271	34	43	oa	oa	NUM
bioscience-271	34	44	treated	treat	VERB
bioscience-271	34	45	and	and	CCONJ
bioscience-271	34	46	[	[	X
bioscience-271	34	47	g	g	X
bioscience-271	34	48	]	]	PUNCT
bioscience-271	34	49	untreated	untreated	ADJ
bioscience-271	34	50	;	;	PUNCT
bioscience-271	34	51	and	and	CCONJ
bioscience-271	34	52	[	[	X
bioscience-271	34	53	h	h	X
bioscience-271	34	54	]	]	X
bioscience-271	34	55	dpi	dpi	NOUN
bioscience-271	34	56	21	21	NUM
bioscience-271	34	57	oa	oa	PRON
bioscience-271	34	58	treated	treat	VERB
bioscience-271	35	1	and	and	CCONJ
bioscience-271	35	2	[	[	X
bioscience-271	35	3	i	i	X
bioscience-271	35	4	]	]	PUNCT
bioscience-271	35	5	untreated	untreated	ADJ
bioscience-271	35	6	.	.	PUNCT
bioscience-271	36	1	dmp	dmp	NOUN
bioscience-271	36	2	:	:	PUNCT
bioscience-271	36	3	damage	damage	NOUN
bioscience-271	36	4	of	of	ADP
bioscience-271	36	5	meninx	meninx	PROPN
bioscience-271	36	6	primitiva	primitiva	PROPN
bioscience-271	36	7	;	;	PUNCT
bioscience-271	36	8	fh	fh	PROPN
bioscience-271	36	9	:	:	PUNCT
bioscience-271	36	10	focal	focal	ADJ
bioscience-271	36	11	haemorrhage	haemorrhage	NOUN
bioscience-271	36	12	;	;	PUNCT
bioscience-271	36	13	imc	imc	PROPN
bioscience-271	36	14	:	:	PUNCT
bioscience-271	36	15	infiltration	infiltration	NOUN
bioscience-271	36	16	of	of	ADP
bioscience-271	36	17	mononuclear	mononuclear	ADJ
bioscience-271	36	18	cells	cell	NOUN
bioscience-271	36	19	;	;	PUNCT
bioscience-271	36	20	ls	ls	ADJ
bioscience-271	36	21	:	:	PUNCT
bioscience-271	36	22	lifting	lifting	NOUN
bioscience-271	36	23	of	of	ADP
bioscience-271	36	24	superficial	superficial	ADJ
bioscience-271	36	25	layer	layer	NOUN
bioscience-271	36	26	;	;	PUNCT
bioscience-271	36	27	lse	lse	PROPN
bioscience-271	36	28	:	:	PUNCT
bioscience-271	36	29	localized	localized	ADJ
bioscience-271	36	30	spongiform	spongiform	NOUN
bioscience-271	36	31	encephalopathy	encephalopathy	NOUN
bioscience-271	36	32	;	;	PUNCT
bioscience-271	36	33	mp	mp	NOUN
bioscience-271	36	34	:	:	PUNCT
bioscience-271	36	35	meninx	meninx	PROPN
bioscience-271	36	36	primitiva	primitiva	PROPN
bioscience-271	36	37	(	(	PUNCT
bioscience-271	36	38	meningitis	meningitis	NOUN
bioscience-271	36	39	)	)	PUNCT
bioscience-271	36	40	;	;	PUNCT
bioscience-271	36	41	tmp	tmp	NOUN
bioscience-271	36	42	:	:	PUNCT
bioscience-271	36	43	thickening	thickening	NOUN
bioscience-271	36	44	of	of	ADP
bioscience-271	36	45	meninx	meninx	PROPN
bioscience-271	36	46	primitiva	primitiva	PROPN
bioscience-271	36	47	;	;	PUNCT
bioscience-271	36	48	dbp	dbp	PROPN
bioscience-271	36	49	:	:	PUNCT
bioscience-271	36	50	degeneration	degeneration	NOUN
bioscience-271	36	51	of	of	ADP
bioscience-271	36	52	brain	brain	NOUN
bioscience-271	36	53	parenchyma	parenchyma	NOUN
bioscience-271	36	54	;	;	PUNCT
bioscience-271	36	55	and	and	CCONJ
bioscience-271	36	56	v	v	ADP
bioscience-271	36	57	:	:	PUNCT
bioscience-271	36	58	vacuolation	vacuolation	NOUN
bioscience-271	36	59	x200	x200	PROPN
bioscience-271	36	60	,	,	PUNCT
bioscience-271	36	61	h&e	h&e	PROPN
bioscience-271	36	62	staining	staining	NOUN
bioscience-271	36	63	.	.	PUNCT
bioscience-271	37	1	concerns	concern	NOUN
bioscience-271	37	2	about	about	ADP
bioscience-271	37	3	antimicrobial	antimicrobial	ADJ
bioscience-271	37	4	resistance	resistance	NOUN
bioscience-271	37	5	(	(	PUNCT
bioscience-271	37	6	amr	amr	NOUN
bioscience-271	37	7	)	)	PUNCT
bioscience-271	37	8	,	,	PUNCT
bioscience-271	37	9	particularly	particularly	ADV
bioscience-271	37	10	in	in	ADP
bioscience-271	37	11	regions	region	NOUN
bioscience-271	37	12	like	like	ADP
bioscience-271	37	13	china	china	PROPN
bioscience-271	37	14	and	and	CCONJ
bioscience-271	37	15	india	india	PROPN
bioscience-271	38	1	[	[	X
bioscience-271	38	2	10	10	NUM
bioscience-271	38	3	;	;	PUNCT
bioscience-271	38	4	11	11	NUM
bioscience-271	38	5	;	;	PUNCT
bioscience-271	38	6	12	12	NUM
bioscience-271	38	7	;	;	PUNCT
bioscience-271	38	8	13	13	NUM
bioscience-271	38	9	]	]	PUNCT
bioscience-271	38	10	.	.	PUNCT
bioscience-271	39	1	the	the	DET
bioscience-271	39	2	quinolone	quinolone	ADJ
bioscience-271	39	3	antibiotic	antibiotic	NOUN
bioscience-271	39	4	,	,	PUNCT
bioscience-271	39	5	oxolinic	oxolinic	ADJ
bioscience-271	39	6	acid	acid	NOUN
bioscience-271	39	7	(	(	PUNCT
bioscience-271	39	8	oa	oa	NOUN
bioscience-271	39	9	)	)	PUNCT
bioscience-271	39	10	is	be	AUX
bioscience-271	39	11	not	not	PART
bioscience-271	39	12	on	on	ADP
bioscience-271	39	13	the	the	DET
bioscience-271	39	14	list	list	NOUN
bioscience-271	39	15	of	of	ADP
bioscience-271	39	16	approved	approve	VERB
bioscience-271	39	17	drugs	drug	NOUN
bioscience-271	39	18	for	for	ADP
bioscience-271	39	19	use	use	NOUN
bioscience-271	39	20	in	in	ADP
bioscience-271	39	21	finfish	finfish	ADJ
bioscience-271	39	22	production	production	NOUN
bioscience-271	39	23	by	by	ADP
bioscience-271	39	24	the	the	DET
bioscience-271	39	25	food	food	NOUN
bioscience-271	39	26	and	and	CCONJ
bioscience-271	39	27	drug	drug	NOUN
bioscience-271	39	28	administration	administration	NOUN
bioscience-271	39	29	in	in	ADP
bioscience-271	39	30	the	the	DET
bioscience-271	39	31	united	united	PROPN
bioscience-271	39	32	states	states	PROPN
bioscience-271	39	33	[	[	X
bioscience-271	39	34	14	14	NUM
bioscience-271	39	35	]	]	PUNCT
bioscience-271	39	36	.	.	PUNCT
bioscience-271	40	1	it	it	PRON
bioscience-271	40	2	develops	develop	VERB
bioscience-271	40	3	resistant	resistant	ADJ
bioscience-271	40	4	bacterial	bacterial	ADJ
bioscience-271	40	5	strains	strain	NOUN
bioscience-271	40	6	that	that	PRON
bioscience-271	40	7	may	may	AUX
bioscience-271	40	8	threaten	threaten	VERB
bioscience-271	40	9	human	human	ADJ
bioscience-271	40	10	health	health	NOUN
bioscience-271	40	11	[	[	X
bioscience-271	40	12	10	10	NUM
bioscience-271	40	13	;	;	PUNCT
bioscience-271	40	14	15	15	NUM
bioscience-271	40	15	]	]	PUNCT
bioscience-271	40	16	.	.	PUNCT
bioscience-271	41	1	however	however	ADV
bioscience-271	41	2	,	,	PUNCT
bioscience-271	41	3	the	the	DET
bioscience-271	41	4	european	european	PROPN
bioscience-271	41	5	union	union	PROPN
bioscience-271	41	6	,	,	PUNCT
bioscience-271	41	7	japan	japan	PROPN
bioscience-271	41	8	,	,	PUNCT
bioscience-271	41	9	and	and	CCONJ
bioscience-271	41	10	other	other	ADJ
bioscience-271	41	11	asian	asian	ADJ
bioscience-271	41	12	countries	country	NOUN
bioscience-271	41	13	have	have	AUX
bioscience-271	41	14	recommended	recommend	VERB
bioscience-271	41	15	it	it	PRON
bioscience-271	41	16	to	to	PART
bioscience-271	41	17	prevent	prevent	VERB
bioscience-271	41	18	bacterial	bacterial	ADJ
bioscience-271	41	19	infections	infection	NOUN
bioscience-271	41	20	at	at	ADP
bioscience-271	41	21	12	12	NUM
bioscience-271	41	22	mg	mg	NUM
bioscience-271	41	23	/	/	SYM
bioscience-271	41	24	kg	kg	NOUN
bioscience-271	41	25	fish	fish	NOUN
bioscience-271	41	26	/	/	SYM
bioscience-271	41	27	day	day	NOUN
bioscience-271	41	28	for	for	ADP
bioscience-271	41	29	7	7	NUM
bioscience-271	41	30	days	day	NOUN
bioscience-271	41	31	[	[	X
bioscience-271	41	32	11	11	NUM
bioscience-271	41	33	;	;	PUNCT
bioscience-271	41	34	16	16	NUM
bioscience-271	41	35	]	]	PUNCT
bioscience-271	41	36	.	.	PUNCT
bioscience-271	42	1	the	the	DET
bioscience-271	42	2	antibiotics	antibiotic	NOUN
bioscience-271	42	3	of	of	ADP
bioscience-271	42	4	the	the	DET
bioscience-271	42	5	quinolone	quinolone	NOUN
bioscience-271	42	6	family	family	NOUN
bioscience-271	42	7	are	be	AUX
bioscience-271	42	8	categorized	categorize	VERB
bioscience-271	42	9	as	as	ADP
bioscience-271	42	10	critically	critically	ADV
bioscience-271	42	11	important	important	ADJ
bioscience-271	42	12	and	and	CCONJ
bioscience-271	42	13	the	the	DET
bioscience-271	42	14	highest	high	ADJ
bioscience-271	42	15	priority	priority	NOUN
bioscience-271	42	16	antimicrobial	antimicrobial	ADJ
bioscience-271	42	17	group	group	NOUN
bioscience-271	42	18	for	for	ADP
bioscience-271	42	19	human	human	ADJ
bioscience-271	42	20	use	use	NOUN
bioscience-271	42	21	.	.	PUNCT
bioscience-271	43	1	such	such	ADJ
bioscience-271	43	2	medicines	medicine	NOUN
bioscience-271	43	3	should	should	AUX
bioscience-271	43	4	not	not	PART
bioscience-271	43	5	be	be	AUX
bioscience-271	43	6	used	use	VERB
bioscience-271	43	7	to	to	PART
bioscience-271	43	8	treat	treat	VERB
bioscience-271	43	9	infectious	infectious	ADJ
bioscience-271	43	10	diseases	disease	NOUN
bioscience-271	43	11	in	in	ADP
bioscience-271	43	12	food	food	NOUN
bioscience-271	43	13	-	-	PUNCT
bioscience-271	43	14	producing	produce	VERB
bioscience-271	43	15	animals	animal	NOUN
bioscience-271	43	16	.	.	PUNCT
bioscience-271	44	1	yet	yet	ADV
bioscience-271	44	2	,	,	PUNCT
bioscience-271	44	3	these	these	DET
bioscience-271	44	4	medicines	medicine	NOUN
bioscience-271	44	5	are	be	AUX
bioscience-271	44	6	proposed	propose	VERB
bioscience-271	44	7	for	for	ADP
bioscience-271	44	8	a	a	DET
bioscience-271	44	9	second	second	ADJ
bioscience-271	44	10	-	-	PUNCT
bioscience-271	44	11	line	line	NOUN
bioscience-271	44	12	treatment	treatment	NOUN
bioscience-271	44	13	in	in	ADP
bioscience-271	44	14	food	food	NOUN
bioscience-271	44	15	-	-	PUNCT
bioscience-271	44	16	producing	produce	VERB
bioscience-271	44	17	animals	animal	NOUN
bioscience-271	44	18	,	,	PUNCT
bioscience-271	44	19	complying	comply	VERB
bioscience-271	44	20	with	with	ADP
bioscience-271	44	21	the	the	DET
bioscience-271	44	22	national	national	ADJ
bioscience-271	44	23	legislation	legislation	NOUN
bioscience-271	44	24	in	in	ADP
bioscience-271	44	25	force	force	NOUN
bioscience-271	44	26	,	,	PUNCT
bioscience-271	44	27	when	when	SCONJ
bioscience-271	44	28	no	no	DET
bioscience-271	44	29	other	other	ADJ
bioscience-271	44	30	alternatives	alternative	NOUN
bioscience-271	44	31	are	be	AUX
bioscience-271	44	32	available	available	ADJ
bioscience-271	44	33	[	[	X
bioscience-271	44	34	15	15	NUM
bioscience-271	44	35	;	;	PUNCT
bioscience-271	44	36	17	17	NUM
bioscience-271	44	37	;	;	PUNCT
bioscience-271	44	38	18	18	NUM
bioscience-271	44	39	]	]	PUNCT
bioscience-271	44	40	.	.	PUNCT
bioscience-271	45	1	several	several	ADJ
bioscience-271	45	2	studies	study	NOUN
bioscience-271	45	3	reported	report	VERB
bioscience-271	45	4	the	the	DET
bioscience-271	45	5	effectiveness	effectiveness	NOUN
bioscience-271	45	6	of	of	ADP
bioscience-271	45	7	oa	oa	NOUN
bioscience-271	45	8	in	in	ADP
bioscience-271	45	9	controlling	control	VERB
bioscience-271	45	10	fish	fish	NOUN
bioscience-271	45	11	bacterial	bacterial	ADJ
bioscience-271	45	12	pathogens	pathogen	NOUN
bioscience-271	45	13	and	and	CCONJ
bioscience-271	45	14	the	the	DET
bioscience-271	45	15	onset	onset	NOUN
bioscience-271	45	16	of	of	ADP
bioscience-271	45	17	diseases	disease	NOUN
bioscience-271	45	18	[	[	X
bioscience-271	45	19	19	19	NUM
bioscience-271	45	20	;	;	PUNCT
bioscience-271	45	21	20	20	NUM
bioscience-271	45	22	;	;	PUNCT
bioscience-271	45	23	21	21	NUM
bioscience-271	45	24	;	;	PUNCT
bioscience-271	45	25	22	22	NUM
bioscience-271	45	26	]	]	PUNCT
bioscience-271	45	27	.	.	PUNCT
bioscience-271	46	1	however	however	ADV
bioscience-271	46	2	,	,	PUNCT
bioscience-271	46	3	more	more	ADJ
bioscience-271	46	4	research	research	NOUN
bioscience-271	46	5	is	be	AUX
bioscience-271	46	6	needed	need	VERB
bioscience-271	46	7	to	to	PART
bioscience-271	46	8	evaluate	evaluate	VERB
bioscience-271	46	9	its	its	PRON
bioscience-271	46	10	mode	mode	NOUN
bioscience-271	46	11	of	of	ADP
bioscience-271	46	12	action	action	NOUN
bioscience-271	46	13	,	,	PUNCT
bioscience-271	46	14	safety	safety	NOUN
bioscience-271	46	15	in	in	ADP
bioscience-271	46	16	tropical	tropical	ADJ
bioscience-271	46	17	fish	fish	NOUN
bioscience-271	46	18	species	specie	NOUN
bioscience-271	46	19	,	,	PUNCT
bioscience-271	46	20	and	and	CCONJ
bioscience-271	46	21	efficacy	efficacy	NOUN
bioscience-271	46	22	against	against	ADP
bioscience-271	46	23	several	several	ADJ
bioscience-271	46	24	mesophilic	mesophilic	ADJ
bioscience-271	46	25	fish	fish	NOUN
bioscience-271	46	26	pathogens	pathogen	NOUN
bioscience-271	46	27	to	to	PART
bioscience-271	46	28	ensure	ensure	VERB
bioscience-271	46	29	sustainable	sustainable	ADJ
bioscience-271	46	30	aquaculture	aquaculture	NOUN
bioscience-271	46	31	pracfigure	pracfigure	NOUN
bioscience-271	46	32	2	2	NUM
bioscience-271	46	33	.	.	PUNCT
bioscience-271	47	1	the	the	DET
bioscience-271	47	2	histopathological	histopathological	ADJ
bioscience-271	47	3	changes	change	NOUN
bioscience-271	47	4	in	in	ADP
bioscience-271	47	5	the	the	DET
bioscience-271	47	6	optic	optic	ADJ
bioscience-271	47	7	tectum	tectum	NOUN
bioscience-271	47	8	(	(	PUNCT
bioscience-271	47	9	ot	ot	ADJ
bioscience-271	47	10	)	)	PUNCT
bioscience-271	47	11	region	region	NOUN
bioscience-271	47	12	of	of	ADP
bioscience-271	47	13	the	the	DET
bioscience-271	47	14	brain	brain	NOUN
bioscience-271	47	15	of	of	ADP
bioscience-271	47	16	streptococcus	streptococcus	NOUN
bioscience-271	47	17	agalactiae	agalactiae	PROPN
bioscience-271	47	18	lcr1	lcr1	PROPN
bioscience-271	47	19	challenged	challenge	VERB
bioscience-271	47	20	and	and	CCONJ
bioscience-271	47	21	oxolinic	oxolinic	ADJ
bioscience-271	47	22	acid	acid	NOUN
bioscience-271	47	23	(	(	PUNCT
bioscience-271	47	24	oa	oa	INTJ
bioscience-271	47	25	)	)	PUNCT
bioscience-271	47	26	treated	treat	VERB
bioscience-271	47	27	and	and	CCONJ
bioscience-271	47	28	untreated	untreate	VERB
bioscience-271	47	29	oreochromis	oreochromis	PROPN
bioscience-271	47	30	niloticus	niloticus	PROPN
bioscience-271	47	31	juveniles	juvenile	NOUN
bioscience-271	47	32	.	.	PUNCT
bioscience-271	48	1	[	[	X
bioscience-271	48	2	a	a	X
bioscience-271	48	3	]	]	X
bioscience-271	48	4	control	control	NOUN
bioscience-271	48	5	,	,	PUNCT
bioscience-271	48	6	[	[	X
bioscience-271	48	7	b	b	X
bioscience-271	48	8	]	]	X
bioscience-271	48	9	day	day	NOUN
bioscience-271	48	10	post	post	NOUN
bioscience-271	48	11	-	-	NOUN
bioscience-271	48	12	injection	injection	ADJ
bioscience-271	48	13	(	(	PUNCT
bioscience-271	48	14	dpi	dpi	NOUN
bioscience-271	48	15	)	)	PUNCT
bioscience-271	48	16	1	1	NUM
bioscience-271	48	17	oa	oa	PRON
bioscience-271	48	18	treated	treat	VERB
bioscience-271	48	19	and	and	CCONJ
bioscience-271	48	20	[	[	X
bioscience-271	48	21	c	c	X
bioscience-271	48	22	]	]	X
bioscience-271	48	23	untreated	untreated	ADJ
bioscience-271	48	24	;	;	PUNCT
bioscience-271	48	25	[	[	X
bioscience-271	48	26	d	d	X
bioscience-271	48	27	]	]	X
bioscience-271	48	28	dpi	dpi	NOUN
bioscience-271	48	29	7	7	NUM
bioscience-271	48	30	oa	oa	NOUN
bioscience-271	48	31	treated	treat	VERB
bioscience-271	48	32	and	and	CCONJ
bioscience-271	48	33	[	[	X
bioscience-271	48	34	e	e	X
bioscience-271	48	35	]	]	X
bioscience-271	48	36	untreated	untreated	ADJ
bioscience-271	48	37	;	;	PUNCT
bioscience-271	48	38	[	[	X
bioscience-271	48	39	f	f	X
bioscience-271	48	40	]	]	X
bioscience-271	48	41	dpi	dpi	NOUN
bioscience-271	48	42	14	14	NUM
bioscience-271	48	43	oa	oa	NUM
bioscience-271	48	44	treated	treat	VERB
bioscience-271	48	45	and	and	CCONJ
bioscience-271	48	46	[	[	X
bioscience-271	48	47	g	g	X
bioscience-271	48	48	]	]	PUNCT
bioscience-271	48	49	untreated	untreated	ADJ
bioscience-271	48	50	;	;	PUNCT
bioscience-271	48	51	and	and	CCONJ
bioscience-271	48	52	[	[	X
bioscience-271	48	53	h	h	X
bioscience-271	48	54	]	]	X
bioscience-271	48	55	dpi	dpi	NOUN
bioscience-271	48	56	21	21	NUM
bioscience-271	48	57	oa	oa	PRON
bioscience-271	48	58	treated	treat	VERB
bioscience-271	49	1	and	and	CCONJ
bioscience-271	49	2	[	[	X
bioscience-271	49	3	i	i	X
bioscience-271	49	4	]	]	PUNCT
bioscience-271	49	5	untreated	untreated	ADJ
bioscience-271	49	6	.	.	PUNCT
bioscience-271	50	1	eot	eot	NOUN
bioscience-271	50	2	:	:	PUNCT
bioscience-271	50	3	edematous	edematous	ADJ
bioscience-271	50	4	optic	optic	ADJ
bioscience-271	50	5	tectum	tectum	NOUN
bioscience-271	50	6	;	;	PUNCT
bioscience-271	50	7	il	il	PROPN
bioscience-271	50	8	:	:	PUNCT
bioscience-271	50	9	infiltration	infiltration	NOUN
bioscience-271	50	10	of	of	ADP
bioscience-271	50	11	leucocytes	leucocyte	NOUN
bioscience-271	50	12	;	;	PUNCT
bioscience-271	50	13	imc	imc	PROPN
bioscience-271	50	14	:	:	PUNCT
bioscience-271	50	15	infiltration	infiltration	NOUN
bioscience-271	50	16	of	of	ADP
bioscience-271	50	17	mononuclear	mononuclear	ADJ
bioscience-271	50	18	cells	cell	NOUN
bioscience-271	50	19	;	;	PUNCT
bioscience-271	50	20	ldc	ldc	PROPN
bioscience-271	50	21	:	:	PUNCT
bioscience-271	50	22	loosened	loosen	VERB
bioscience-271	50	23	dense	dense	ADJ
bioscience-271	50	24	connective	connective	ADJ
bioscience-271	50	25	tissue	tissue	NOUN
bioscience-271	50	26	;	;	PUNCT
bioscience-271	50	27	ls	ls	ADJ
bioscience-271	50	28	:	:	PUNCT
bioscience-271	50	29	lifting	lifting	NOUN
bioscience-271	50	30	of	of	ADP
bioscience-271	50	31	superficial	superficial	ADJ
bioscience-271	50	32	layer	layer	NOUN
bioscience-271	50	33	;	;	PUNCT
bioscience-271	50	34	lse	lse	PROPN
bioscience-271	50	35	:	:	PUNCT
bioscience-271	50	36	localized	localized	ADJ
bioscience-271	50	37	spongiform	spongiform	NOUN
bioscience-271	50	38	encephalopathy	encephalopathy	NOUN
bioscience-271	50	39	;	;	PUNCT
bioscience-271	50	40	mp	mp	NOUN
bioscience-271	50	41	:	:	PUNCT
bioscience-271	50	42	meninx	meninx	PROPN
bioscience-271	50	43	primitiva	primitiva	PROPN
bioscience-271	50	44	;	;	PUNCT
bioscience-271	50	45	slc	slc	PROPN
bioscience-271	50	46	:	:	PUNCT
bioscience-271	50	47	spacing	space	VERB
bioscience-271	50	48	in	in	ADP
bioscience-271	50	49	loose	loose	ADJ
bioscience-271	50	50	connective	connective	ADJ
bioscience-271	50	51	tissue	tissue	NOUN
bioscience-271	50	52	;	;	PUNCT
bioscience-271	50	53	tmp	tmp	NOUN
bioscience-271	50	54	:	:	PUNCT
bioscience-271	50	55	thickening	thickening	NOUN
bioscience-271	50	56	of	of	ADP
bioscience-271	50	57	meninx	meninx	PROPN
bioscience-271	50	58	primitiva	primitiva	PROPN
bioscience-271	50	59	;	;	PUNCT
bioscience-271	50	60	and	and	CCONJ
bioscience-271	50	61	v	v	ADP
bioscience-271	50	62	:	:	PUNCT
bioscience-271	50	63	vacuolation	vacuolation	NOUN
bioscience-271	50	64	x200	x200	PROPN
bioscience-271	50	65	,	,	PUNCT
bioscience-271	50	66	h&e	h&e	PROPN
bioscience-271	50	67	staining	staining	NOUN
bioscience-271	50	68	.	.	PUNCT
bioscience-271	51	1	tices	tice	NOUN
bioscience-271	52	1	[	[	X
bioscience-271	52	2	23	23	NUM
bioscience-271	52	3	]	]	PUNCT
bioscience-271	52	4	.	.	PUNCT
bioscience-271	53	1	the	the	DET
bioscience-271	53	2	infection	infection	NOUN
bioscience-271	53	3	of	of	ADP
bioscience-271	53	4	sa	sa	PROPN
bioscience-271	53	5	relies	rely	VERB
bioscience-271	53	6	on	on	ADP
bioscience-271	53	7	several	several	ADJ
bioscience-271	53	8	virulence	virulence	NOUN
bioscience-271	53	9	factors	factor	NOUN
bioscience-271	53	10	,	,	PUNCT
bioscience-271	53	11	which	which	PRON
bioscience-271	53	12	encompass	encompass	VERB
bioscience-271	53	13	adhesion	adhesion	NOUN
bioscience-271	53	14	,	,	PUNCT
bioscience-271	53	15	invasion	invasion	NOUN
bioscience-271	53	16	,	,	PUNCT
bioscience-271	53	17	and	and	CCONJ
bioscience-271	53	18	infection	infection	NOUN
bioscience-271	53	19	.	.	PUNCT
bioscience-271	54	1	numerous	numerous	ADJ
bioscience-271	54	2	virulence	virulence	NOUN
bioscience-271	54	3	factors	factor	NOUN
bioscience-271	54	4	contribute	contribute	VERB
bioscience-271	54	5	to	to	ADP
bioscience-271	54	6	invasion	invasion	NOUN
bioscience-271	54	7	and	and	CCONJ
bioscience-271	54	8	colonisation	colonisation	NOUN
bioscience-271	54	9	[	[	X
bioscience-271	54	10	24	24	NUM
bioscience-271	54	11	;	;	PUNCT
bioscience-271	54	12	25	25	NUM
bioscience-271	54	13	]	]	PUNCT
bioscience-271	54	14	.	.	PUNCT
bioscience-271	55	1	the	the	DET
bioscience-271	55	2	relationship	relationship	NOUN
bioscience-271	55	3	between	between	ADP
bioscience-271	55	4	antibiotics	antibiotic	NOUN
bioscience-271	55	5	,	,	PUNCT
bioscience-271	55	6	virulence	virulence	NOUN
bioscience-271	55	7	proteins	protein	NOUN
bioscience-271	55	8	,	,	PUNCT
bioscience-271	55	9	and	and	CCONJ
bioscience-271	55	10	the	the	DET
bioscience-271	55	11	ability	ability	NOUN
bioscience-271	55	12	of	of	ADP
bioscience-271	55	13	bacteria	bacteria	NOUN
bioscience-271	55	14	to	to	PART
bioscience-271	55	15	infect	infect	VERB
bioscience-271	55	16	the	the	DET
bioscience-271	55	17	brain	brain	NOUN
bioscience-271	55	18	is	be	AUX
bioscience-271	55	19	complex	complex	ADJ
bioscience-271	55	20	,	,	PUNCT
bioscience-271	55	21	involving	involve	VERB
bioscience-271	55	22	factors	factor	NOUN
bioscience-271	55	23	like	like	ADP
bioscience-271	55	24	the	the	DET
bioscience-271	55	25	blood	blood	NOUN
bioscience-271	55	26	-	-	PUNCT
bioscience-271	55	27	brain	brain	NOUN
bioscience-271	55	28	barrier	barrier	NOUN
bioscience-271	55	29	(	(	PUNCT
bioscience-271	55	30	bbb	bbb	NOUN
bioscience-271	55	31	)	)	PUNCT
bioscience-271	55	32	and	and	CCONJ
bioscience-271	55	33	host	host	NOUN
bioscience-271	55	34	immune	immune	ADJ
bioscience-271	55	35	responses	response	NOUN
bioscience-271	55	36	.	.	PUNCT
bioscience-271	56	1	for	for	ADP
bioscience-271	56	2	example	example	NOUN
bioscience-271	56	3	,	,	PUNCT
bioscience-271	56	4	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	56	5	and	and	CCONJ
bioscience-271	56	6	the	the	DET
bioscience-271	56	7	camp	camp	NOUN
bioscience-271	56	8	factor	factor	NOUN
bioscience-271	56	9	play	play	VERB
bioscience-271	56	10	crucial	crucial	ADJ
bioscience-271	56	11	roles	role	NOUN
bioscience-271	56	12	in	in	ADP
bioscience-271	56	13	pathogenesis	pathogenesis	NOUN
bioscience-271	56	14	,	,	PUNCT
bioscience-271	56	15	as	as	SCONJ
bioscience-271	56	16	highly	highly	ADV
bioscience-271	56	17	pathogenic	pathogenic	ADJ
bioscience-271	56	18	strains	strain	NOUN
bioscience-271	56	19	of	of	ADP
bioscience-271	56	20	sa	sa	NOUN
bioscience-271	56	21	reportedly	reportedly	ADV
bioscience-271	56	22	produce	produce	VERB
bioscience-271	56	23	glycosylated	glycosylated	ADJ
bioscience-271	56	24	serine	serine	NOUN
bioscience-271	56	25	-	-	PUNCT
bioscience-271	56	26	rich	rich	ADJ
bioscience-271	56	27	repeats	repeat	NOUN
bioscience-271	56	28	and	and	CCONJ
bioscience-271	56	29	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	56	30	[	[	X
bioscience-271	56	31	26	26	NUM
bioscience-271	56	32	;	;	PUNCT
bioscience-271	56	33	27	27	NUM
bioscience-271	56	34	]	]	PUNCT
bioscience-271	56	35	.	.	PUNCT
bioscience-271	57	1	the	the	DET
bioscience-271	57	2	extracellular	extracellular	ADJ
bioscience-271	57	3	protein	protein	NOUN
bioscience-271	57	4	,	,	PUNCT
bioscience-271	57	5	such	such	ADJ
bioscience-271	57	6	as	as	ADP
bioscience-271	57	7	camp	camp	NOUN
bioscience-271	57	8	factor	factor	NOUN
bioscience-271	57	9	,	,	PUNCT
bioscience-271	57	10	induces	induce	VERB
bioscience-271	57	11	pore	pore	ADJ
bioscience-271	57	12	formation	formation	NOUN
bioscience-271	57	13	in	in	ADP
bioscience-271	57	14	target	target	NOUN
bioscience-271	57	15	cells	cell	NOUN
bioscience-271	57	16	and	and	CCONJ
bioscience-271	57	17	heightens	heighten	VERB
bioscience-271	57	18	the	the	DET
bioscience-271	57	19	pathogenicity	pathogenicity	NOUN
bioscience-271	57	20	of	of	ADP
bioscience-271	57	21	sa	sa	PROPN
bioscience-271	58	1	[	[	X
bioscience-271	58	2	24	24	NUM
bioscience-271	58	3	;	;	PUNCT
bioscience-271	58	4	25	25	NUM
bioscience-271	58	5	;	;	PUNCT
bioscience-271	58	6	28	28	NUM
bioscience-271	58	7	]	]	PUNCT
bioscience-271	58	8	.	.	PUNCT
bioscience-271	59	1	however	however	ADV
bioscience-271	59	2	,	,	PUNCT
bioscience-271	59	3	there	there	PRON
bioscience-271	59	4	is	be	VERB
bioscience-271	59	5	a	a	DET
bioscience-271	59	6	lack	lack	NOUN
bioscience-271	59	7	of	of	ADP
bioscience-271	59	8	scientific	scientific	ADJ
bioscience-271	59	9	literature	literature	NOUN
bioscience-271	59	10	focusing	focus	VERB
bioscience-271	59	11	on	on	ADP
bioscience-271	59	12	the	the	DET
bioscience-271	59	13	specific	specific	ADJ
bioscience-271	59	14	effects	effect	NOUN
bioscience-271	59	15	of	of	ADP
bioscience-271	59	16	aquaculture	aquaculture	NOUN
bioscience-271	59	17	antibiotics	antibiotic	NOUN
bioscience-271	59	18	on	on	ADP
bioscience-271	59	19	brain	brain	NOUN
bioscience-271	59	20	-	-	PUNCT
bioscience-271	59	21	infecting	infect	VERB
bioscience-271	59	22	bacteria	bacteria	NOUN
bioscience-271	59	23	,	,	PUNCT
bioscience-271	59	24	such	such	ADJ
bioscience-271	59	25	as	as	ADP
bioscience-271	59	26	sa	sa	PROPN
bioscience-271	59	27	,	,	PUNCT
bioscience-271	59	28	and	and	CCONJ
bioscience-271	59	29	their	their	PRON
bioscience-271	59	30	virulence	virulence	NOUN
bioscience-271	59	31	proteins	protein	NOUN
bioscience-271	59	32	.	.	PUNCT
bioscience-271	60	1	also	also	ADV
bioscience-271	60	2	,	,	PUNCT
bioscience-271	60	3	the	the	DET
bioscience-271	60	4	misuse	misuse	NOUN
bioscience-271	60	5	of	of	ADP
bioscience-271	60	6	antibiotics	antibiotic	NOUN
bioscience-271	60	7	can	can	AUX
bioscience-271	60	8	lead	lead	VERB
bioscience-271	60	9	to	to	ADP
bioscience-271	60	10	the	the	DET
bioscience-271	60	11	emergence	emergence	NOUN
bioscience-271	60	12	of	of	ADP
bioscience-271	60	13	amr	amr	NOUN
bioscience-271	60	14	,	,	PUNCT
bioscience-271	60	15	which	which	PRON
bioscience-271	60	16	is	be	AUX
bioscience-271	60	17	a	a	DET
bioscience-271	60	18	significant	significant	ADJ
bioscience-271	60	19	public	public	ADJ
bioscience-271	60	20	health	health	NOUN
bioscience-271	60	21	concern	concern	NOUN
bioscience-271	60	22	[	[	X
bioscience-271	60	23	10	10	NUM
bioscience-271	60	24	;	;	PUNCT
bioscience-271	60	25	15	15	NUM
bioscience-271	60	26	]	]	PUNCT
bioscience-271	60	27	.	.	PUNCT
bioscience-271	61	1	therefore	therefore	ADV
bioscience-271	61	2	,	,	PUNCT
bioscience-271	61	3	to	to	PART
bioscience-271	61	4	combat	combat	NOUN
bioscience-271	61	5	sa	sa	PROPN
bioscience-271	61	6	infections	infection	NOUN
bioscience-271	61	7	,	,	PUNCT
bioscience-271	61	8	understanding	understand	VERB
bioscience-271	61	9	the	the	DET
bioscience-271	61	10	roles	role	NOUN
bioscience-271	61	11	of	of	ADP
bioscience-271	61	12	important	important	ADJ
bioscience-271	61	13	virulent	virulent	ADJ
bioscience-271	61	14	proteins	protein	NOUN
bioscience-271	61	15	and	and	CCONJ
bioscience-271	61	16	their	their	PRON
bioscience-271	61	17	interaction	interaction	NOUN
bioscience-271	61	18	with	with	ADP
bioscience-271	61	19	antibiotics	antibiotic	NOUN
bioscience-271	61	20	is	be	AUX
bioscience-271	61	21	essential	essential	ADJ
bioscience-271	61	22	.	.	PUNCT
bioscience-271	62	1	this	this	DET
bioscience-271	62	2	study	study	NOUN
bioscience-271	62	3	delved	delve	VERB
bioscience-271	62	4	into	into	ADP
bioscience-271	62	5	the	the	DET
bioscience-271	62	6	efficacy	efficacy	NOUN
bioscience-271	62	7	of	of	ADP
bioscience-271	62	8	oa	oa	PROPN
bioscience-271	62	9	,	,	PUNCT
bioscience-271	62	10	an	an	DET
bioscience-271	62	11	antibiotic	antibiotic	NOUN
bioscience-271	62	12	recommended	recommend	VERB
bioscience-271	62	13	for	for	ADP
bioscience-271	62	14	second	second	ADJ
bioscience-271	62	15	-	-	PUNCT
bioscience-271	62	16	line	line	NOUN
bioscience-271	62	17	treatment	treatment	NOUN
bioscience-271	62	18	in	in	ADP
bioscience-271	62	19	food	food	NOUN
bioscience-271	62	20	-	-	PUNCT
bioscience-271	62	21	producing	produce	VERB
bioscience-271	62	22	animals	animal	NOUN
bioscience-271	62	23	[	[	X
bioscience-271	62	24	18	18	NUM
bioscience-271	62	25	]	]	PUNCT
bioscience-271	62	26	,	,	PUNCT
bioscience-271	62	27	to	to	PART
bioscience-271	62	28	curtail	curtail	VERB
bioscience-271	62	29	the	the	DET
bioscience-271	62	30	effect	effect	NOUN
bioscience-271	62	31	of	of	ADP
bioscience-271	62	32	sa	sa	NOUN
bioscience-271	62	33	-	-	PUNCT
bioscience-271	62	34	infection	infection	NOUN
bioscience-271	62	35	on	on	ADP
bioscience-271	62	36	the	the	DET
bioscience-271	62	37	brain	brain	NOUN
bioscience-271	62	38	histoarchitecture	histoarchitecture	NOUN
bioscience-271	62	39	of	of	ADP
bioscience-271	62	40	nile	nile	PROPN
bioscience-271	62	41	tilapia	tilapia	PROPN
bioscience-271	62	42	oreochromis	oreochromis	PROPN
bioscience-271	62	43	niloticus	niloticus	PROPN
bioscience-271	62	44	,	,	PUNCT
bioscience-271	62	45	and	and	CCONJ
bioscience-271	62	46	to	to	PART
bioscience-271	62	47	comprehend	comprehend	VERB
bioscience-271	62	48	how	how	SCONJ
bioscience-271	62	49	oa	oa	NOUN
bioscience-271	62	50	impacts	impact	VERB
bioscience-271	62	51	the	the	DET
bioscience-271	62	52	invasion	invasion	NOUN
bioscience-271	62	53	of	of	ADP
bioscience-271	62	54	sa	sa	NOUN
bioscience-271	62	55	into	into	ADP
bioscience-271	62	56	the	the	DET
bioscience-271	62	57	fish	fish	NOUN
bioscience-271	62	58	brain	brain	NOUN
bioscience-271	62	59	by	by	ADP
bioscience-271	62	60	molecular	molecular	ADJ
bioscience-271	62	61	docking	docking	NOUN
bioscience-271	62	62	highlights	highlight	NOUN
bioscience-271	62	63	in	in	ADP
bioscience-271	62	64	bioscience	bioscience	NOUN
bioscience-271	62	65	page	page	NOUN
bioscience-271	62	66	2	2	NUM
bioscience-271	62	67	of	of	ADP
bioscience-271	62	68	10	10	NUM
bioscience-271	62	69	october	october	PROPN
bioscience-271	62	70	2025|volume	2025|volume	NUM
bioscience-271	62	71	8	8	NUM
bioscience-271	62	72	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	62	73	sinha	sinha	PROPN
bioscience-271	62	74	p	p	PROPN
bioscience-271	62	75	et	et	PROPN
bioscience-271	62	76	al	al	PROPN
bioscience-271	62	77	.	.	PROPN
bioscience-271	62	78	,	,	PUNCT
bioscience-271	62	79	2025	2025	NUM
bioscience-271	62	80	effect	effect	NOUN
bioscience-271	62	81	of	of	ADP
bioscience-271	62	82	oxolinic	oxolinic	ADJ
bioscience-271	62	83	acid	acid	NOUN
bioscience-271	62	84	therapy	therapy	NOUN
bioscience-271	62	85	using	use	VERB
bioscience-271	62	86	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	62	87	and	and	CCONJ
bioscience-271	62	88	camp	camp	NOUN
bioscience-271	62	89	factor	factor	NOUN
bioscience-271	62	90	,	,	PUNCT
bioscience-271	62	91	to	to	PART
bioscience-271	62	92	plan	plan	VERB
bioscience-271	62	93	for	for	ADP
bioscience-271	62	94	further	further	ADJ
bioscience-271	62	95	course	course	NOUN
bioscience-271	62	96	of	of	ADP
bioscience-271	62	97	research	research	NOUN
bioscience-271	62	98	and	and	CCONJ
bioscience-271	62	99	specific	specific	ADJ
bioscience-271	62	100	mitigation	mitigation	NOUN
bioscience-271	62	101	strategies	strategy	NOUN
bioscience-271	62	102	.	.	PUNCT
bioscience-271	63	1	materials	material	NOUN
bioscience-271	63	2	and	and	CCONJ
bioscience-271	63	3	methods	method	NOUN
bioscience-271	63	4	experimental	experimental	ADJ
bioscience-271	63	5	fish	fish	NOUN
bioscience-271	63	6	and	and	CCONJ
bioscience-271	63	7	bacterial	bacterial	ADJ
bioscience-271	63	8	strain	strain	NOUN
bioscience-271	63	9	and	and	CCONJ
bioscience-271	63	10	its	its	PRON
bioscience-271	63	11	pathogenicity	pathogenicity	NOUN
bioscience-271	63	12	farm	farm	NOUN
bioscience-271	63	13	-	-	PUNCT
bioscience-271	63	14	raised	raise	VERB
bioscience-271	63	15	young	young	ADJ
bioscience-271	63	16	and	and	CCONJ
bioscience-271	63	17	healthy	healthy	ADJ
bioscience-271	63	18	oreochromis	oreochromis	PROPN
bioscience-271	63	19	niloticus	niloticus	PROPN
bioscience-271	63	20	were	be	AUX
bioscience-271	63	21	chosen	choose	VERB
bioscience-271	63	22	regardless	regardless	ADV
bioscience-271	63	23	of	of	ADP
bioscience-271	63	24	sex	sex	NOUN
bioscience-271	63	25	and	and	CCONJ
bioscience-271	63	26	adapted	adapt	VERB
bioscience-271	63	27	in	in	ADP
bioscience-271	63	28	circular	circular	ADJ
bioscience-271	63	29	tanks	tank	NOUN
bioscience-271	63	30	of	of	ADP
bioscience-271	63	31	500	500	NUM
bioscience-271	63	32	l	l	NOUN
bioscience-271	63	33	capacity	capacity	NOUN
bioscience-271	63	34	for	for	ADP
bioscience-271	63	35	15	15	NUM
bioscience-271	63	36	days	day	NOUN
bioscience-271	63	37	before	before	ADP
bioscience-271	63	38	the	the	DET
bioscience-271	63	39	experimentation	experimentation	NOUN
bioscience-271	63	40	[	[	X
bioscience-271	63	41	23	23	NUM
bioscience-271	63	42	]	]	PUNCT
bioscience-271	63	43	.	.	PUNCT
bioscience-271	64	1	streptococcus	streptococcus	VERB
bioscience-271	64	2	agalactiae	agalactiae	PROPN
bioscience-271	64	3	lcr1	lcr1	PROPN
bioscience-271	64	4	(	(	PUNCT
bioscience-271	64	5	national	national	ADJ
bioscience-271	64	6	centre	centre	NOUN
bioscience-271	64	7	for	for	ADP
bioscience-271	64	8	biotechnology	biotechnology	NOUN
bioscience-271	64	9	information	information	NOUN
bioscience-271	64	10	(	(	PUNCT
bioscience-271	64	11	ncbi	ncbi	NOUN
bioscience-271	64	12	)	)	PUNCT
bioscience-271	64	13	accession	accession	NOUN
bioscience-271	64	14	number	number	NOUN
bioscience-271	64	15	op752129	op752129	PROPN
bioscience-271	64	16	)	)	PUNCT
bioscience-271	64	17	was	be	AUX
bioscience-271	64	18	obtained	obtain	VERB
bioscience-271	64	19	from	from	ADP
bioscience-271	64	20	the	the	DET
bioscience-271	64	21	state	state	NOUN
bioscience-271	64	22	referral	referral	ADJ
bioscience-271	64	23	laboratory	laboratory	NOUN
bioscience-271	64	24	for	for	ADP
bioscience-271	64	25	aquatic	aquatic	ADJ
bioscience-271	64	26	animal	animal	NOUN
bioscience-271	64	27	health	health	NOUN
bioscience-271	64	28	,	,	PUNCT
bioscience-271	64	29	madhavaram	madhavaram	PROPN
bioscience-271	64	30	,	,	PUNCT
bioscience-271	64	31	chennai	chennai	PROPN
bioscience-271	64	32	,	,	PUNCT
bioscience-271	64	33	india	india	PROPN
bioscience-271	64	34	.	.	PUNCT
bioscience-271	65	1	following	follow	VERB
bioscience-271	65	2	earlier	early	ADJ
bioscience-271	65	3	descriptions	description	NOUN
bioscience-271	65	4	,	,	PUNCT
bioscience-271	65	5	the	the	DET
bioscience-271	65	6	bacterium	bacterium	NOUN
bioscience-271	65	7	was	be	AUX
bioscience-271	65	8	assessed	assess	VERB
bioscience-271	65	9	for	for	ADP
bioscience-271	65	10	its	its	PRON
bioscience-271	65	11	pathogenicity	pathogenicity	NOUN
bioscience-271	65	12	against	against	ADP
bioscience-271	65	13	o.	o.	PROPN
bioscience-271	65	14	niloticus	niloticus	PROPN
bioscience-271	65	15	(	(	PUNCT
bioscience-271	65	16	n	n	NOUN
bioscience-271	65	17	=	=	SYM
bioscience-271	65	18	10	10	NUM
bioscience-271	65	19	for	for	ADP
bioscience-271	65	20	each	each	DET
bioscience-271	65	21	challenge	challenge	NOUN
bioscience-271	65	22	dose	dose	VERB
bioscience-271	65	23	from	from	ADP
bioscience-271	65	24	105	105	NUM
bioscience-271	65	25	to	to	PART
bioscience-271	65	26	109	109	NUM
bioscience-271	65	27	and	and	CCONJ
bioscience-271	65	28	control	control	NOUN
bioscience-271	65	29	,	,	PUNCT
bioscience-271	65	30	in	in	ADP
bioscience-271	65	31	triplicate	triplicate	NOUN
bioscience-271	65	32	)	)	PUNCT
bioscience-271	65	33	by	by	ADP
bioscience-271	65	34	intramuscular	intramuscular	ADJ
bioscience-271	65	35	challenge	challenge	NOUN
bioscience-271	65	36	[	[	X
bioscience-271	65	37	29	29	NUM
bioscience-271	65	38	;	;	PUNCT
bioscience-271	65	39	30	30	NUM
bioscience-271	65	40	]	]	PUNCT
bioscience-271	65	41	.	.	PUNCT
bioscience-271	66	1	the	the	DET
bioscience-271	66	2	mean	mean	ADJ
bioscience-271	66	3	lethal	lethal	ADJ
bioscience-271	66	4	dose	dose	NOUN
bioscience-271	66	5	(	(	PUNCT
bioscience-271	66	6	ld50	ld50	PROPN
bioscience-271	66	7	)	)	PUNCT
bioscience-271	66	8	was	be	AUX
bioscience-271	66	9	calculated	calculate	VERB
bioscience-271	66	10	from	from	ADP
bioscience-271	66	11	the	the	DET
bioscience-271	66	12	mortality	mortality	NOUN
bioscience-271	66	13	data	datum	NOUN
bioscience-271	66	14	using	use	VERB
bioscience-271	66	15	the	the	DET
bioscience-271	66	16	method	method	NOUN
bioscience-271	66	17	established	establish	VERB
bioscience-271	66	18	by	by	ADP
bioscience-271	66	19	reed	reed	NOUN
bioscience-271	66	20	and	and	CCONJ
bioscience-271	66	21	muench	muench	ADJ
bioscience-271	66	22	[	[	X
bioscience-271	66	23	31	31	NUM
bioscience-271	66	24	]	]	PUNCT
bioscience-271	66	25	.	.	PUNCT
bioscience-271	67	1	using	use	VERB
bioscience-271	67	2	the	the	DET
bioscience-271	67	3	broth	broth	ADJ
bioscience-271	67	4	dilution	dilution	NOUN
bioscience-271	67	5	method	method	NOUN
bioscience-271	67	6	,	,	PUNCT
bioscience-271	67	7	the	the	DET
bioscience-271	67	8	minimum	minimum	ADJ
bioscience-271	67	9	inhibitory	inhibitory	ADJ
bioscience-271	67	10	concentration	concentration	NOUN
bioscience-271	67	11	(	(	PUNCT
bioscience-271	67	12	mic	mic	NOUN
bioscience-271	67	13	)	)	PUNCT
bioscience-271	67	14	of	of	ADP
bioscience-271	67	15	oa	oa	PRON
bioscience-271	67	16	was	be	AUX
bioscience-271	67	17	calculated	calculate	VERB
bioscience-271	67	18	[	[	X
bioscience-271	67	19	32	32	NUM
bioscience-271	67	20	]	]	PUNCT
bioscience-271	67	21	.	.	PUNCT
bioscience-271	68	1	before	before	ADP
bioscience-271	68	2	the	the	DET
bioscience-271	68	3	challenge	challenge	NOUN
bioscience-271	68	4	,	,	PUNCT
bioscience-271	68	5	inocula	inocula	VERB
bioscience-271	68	6	from	from	ADP
bioscience-271	68	7	the	the	DET
bioscience-271	68	8	kidney	kidney	NOUN
bioscience-271	68	9	of	of	ADP
bioscience-271	68	10	healthy	healthy	ADJ
bioscience-271	68	11	tilapia	tilapia	NOUN
bioscience-271	68	12	(	(	PUNCT
bioscience-271	68	13	n	n	NOUN
bioscience-271	68	14	=	=	SYM
bioscience-271	68	15	2	2	NUM
bioscience-271	68	16	)	)	PUNCT
bioscience-271	68	17	were	be	AUX
bioscience-271	68	18	plated	plate	VERB
bioscience-271	68	19	onto	onto	ADP
bioscience-271	68	20	brain	brain	NOUN
bioscience-271	68	21	heart	heart	NOUN
bioscience-271	68	22	infusion	infusion	NOUN
bioscience-271	68	23	agar	agar	NOUN
bioscience-271	68	24	(	(	PUNCT
bioscience-271	68	25	bhia	bhia	NOUN
bioscience-271	68	26	)	)	PUNCT
bioscience-271	68	27	to	to	PART
bioscience-271	68	28	ascertain	ascertain	VERB
bioscience-271	68	29	that	that	SCONJ
bioscience-271	68	30	the	the	DET
bioscience-271	68	31	stocks	stock	NOUN
bioscience-271	68	32	were	be	AUX
bioscience-271	68	33	disease	disease	NOUN
bioscience-271	68	34	-	-	PUNCT
bioscience-271	68	35	free	free	ADJ
bioscience-271	68	36	[	[	X
bioscience-271	68	37	5	5	NUM
bioscience-271	68	38	]	]	PUNCT
bioscience-271	68	39	.	.	PUNCT
bioscience-271	69	1	efficacy	efficacy	NOUN
bioscience-271	69	2	of	of	ADP
bioscience-271	69	3	oxolinic	oxolinic	ADJ
bioscience-271	69	4	acid	acid	NOUN
bioscience-271	69	5	against	against	ADP
bioscience-271	69	6	streptococcus	streptococcus	NOUN
bioscience-271	69	7	agalactiae	agalactiae	ADJ
bioscience-271	69	8	infection	infection	NOUN
bioscience-271	69	9	the	the	DET
bioscience-271	69	10	european	european	PROPN
bioscience-271	69	11	medicines	medicines	PROPN
bioscience-271	69	12	evaluation	evaluation	NOUN
bioscience-271	69	13	agency	agency	NOUN
bioscience-271	69	14	(	(	PUNCT
bioscience-271	69	15	emea	emea	PROPN
bioscience-271	69	16	)	)	PUNCT
bioscience-271	69	17	recommended	recommend	VERB
bioscience-271	69	18	a	a	DET
bioscience-271	69	19	dose	dose	NOUN
bioscience-271	69	20	of	of	ADP
bioscience-271	69	21	12	12	NUM
bioscience-271	69	22	mg	mg	NOUN
bioscience-271	69	23	oa	oa	PROPN
bioscience-271	69	24	/	/	SYM
bioscience-271	69	25	kg	kg	NOUN
bioscience-271	69	26	fish	fish	NOUN
bioscience-271	69	27	/	/	SYM
bioscience-271	69	28	day	day	NOUN
bioscience-271	69	29	for	for	ADP
bioscience-271	69	30	7	7	NUM
bioscience-271	69	31	uninterrupted	uninterrupted	ADJ
bioscience-271	69	32	days	day	NOUN
bioscience-271	69	33	to	to	PART
bioscience-271	69	34	control	control	VERB
bioscience-271	69	35	bacterial	bacterial	ADJ
bioscience-271	69	36	infection	infection	NOUN
bioscience-271	69	37	in	in	ADP
bioscience-271	69	38	fish	fish	NOUN
bioscience-271	69	39	[	[	X
bioscience-271	69	40	16	16	NUM
bioscience-271	69	41	]	]	PUNCT
bioscience-271	69	42	.	.	PUNCT
bioscience-271	70	1	the	the	DET
bioscience-271	70	2	medicated	medicate	VERB
bioscience-271	70	3	feed	feed	NOUN
bioscience-271	70	4	to	to	PART
bioscience-271	70	5	feed	feed	VERB
bioscience-271	70	6	the	the	DET
bioscience-271	70	7	experimental	experimental	ADJ
bioscience-271	70	8	fish	fish	NOUN
bioscience-271	70	9	at	at	ADP
bioscience-271	70	10	2	2	NUM
bioscience-271	70	11	%	%	NOUN
bioscience-271	70	12	body	body	NOUN
bioscience-271	70	13	weight	weight	NOUN
bioscience-271	70	14	(	(	PUNCT
bioscience-271	70	15	bw	bw	NOUN
bioscience-271	70	16	)	)	PUNCT
bioscience-271	70	17	was	be	AUX
bioscience-271	70	18	set	set	VERB
bioscience-271	70	19	by	by	ADP
bioscience-271	70	20	emulsifying	emulsify	VERB
bioscience-271	70	21	0.6	0.6	NUM
bioscience-271	70	22	g	g	NOUN
bioscience-271	70	23	of	of	ADP
bioscience-271	70	24	oa	oa	PROPN
bioscience-271	70	25	powder	powder	NOUN
bioscience-271	70	26	(	(	PUNCT
bioscience-271	70	27	o0877	o0877	NOUN
bioscience-271	70	28	-	-	PUNCT
bioscience-271	70	29	25	25	NUM
bioscience-271	70	30	g	g	NOUN
bioscience-271	70	31	;	;	PUNCT
bioscience-271	70	32	cas	cas	PROPN
bioscience-271	70	33	-	-	PROPN
bioscience-271	70	34	no	no	NOUN
bioscience-271	70	35	:	:	PUNCT
bioscience-271	70	36	14698	14698	NUM
bioscience-271	70	37	-	-	SYM
bioscience-271	70	38	29	29	NUM
bioscience-271	70	39	-	-	SYM
bioscience-271	70	40	4	4	NUM
bioscience-271	70	41	;	;	PUNCT
bioscience-271	70	42	sigma	sigma	PROPN
bioscience-271	70	43	-	-	PUNCT
bioscience-271	70	44	aldrich	aldrich	PROPN
bioscience-271	70	45	,	,	PUNCT
bioscience-271	70	46	india	india	PROPN
bioscience-271	70	47	)	)	PUNCT
bioscience-271	70	48	in	in	ADP
bioscience-271	70	49	5	5	NUM
bioscience-271	70	50	ml	ml	NOUN
bioscience-271	70	51	vegetable	vegetable	NOUN
bioscience-271	70	52	oil	oil	NOUN
bioscience-271	70	53	.	.	PUNCT
bioscience-271	71	1	this	this	DET
bioscience-271	71	2	emulsion	emulsion	NOUN
bioscience-271	71	3	was	be	AUX
bioscience-271	71	4	then	then	ADV
bioscience-271	71	5	top	top	ADV
bioscience-271	71	6	-	-	PUNCT
bioscience-271	71	7	coated	coated	ADJ
bioscience-271	71	8	onto	onto	ADP
bioscience-271	71	9	the	the	DET
bioscience-271	71	10	commercial	commercial	ADJ
bioscience-271	71	11	floating	float	VERB
bioscience-271	71	12	pellet	pellet	NOUN
bioscience-271	71	13	feed	feed	NOUN
bioscience-271	71	14	(	(	PUNCT
bioscience-271	71	15	1	1	NUM
bioscience-271	71	16	kg	kg	NOUN
bioscience-271	71	17	)	)	PUNCT
bioscience-271	71	18	and	and	CCONJ
bioscience-271	71	19	admixed	admix	VERB
bioscience-271	71	20	thoroughly	thoroughly	ADV
bioscience-271	71	21	.	.	PUNCT
bioscience-271	72	1	correspondingly	correspondingly	ADV
bioscience-271	72	2	,	,	PUNCT
bioscience-271	72	3	a	a	DET
bioscience-271	72	4	control	control	NOUN
bioscience-271	72	5	feed	feed	NOUN
bioscience-271	72	6	with	with	ADP
bioscience-271	72	7	binder	binder	NOUN
bioscience-271	72	8	but	but	CCONJ
bioscience-271	72	9	without	without	ADP
bioscience-271	72	10	oa	oa	PROPN
bioscience-271	72	11	was	be	AUX
bioscience-271	72	12	prepared	prepare	VERB
bioscience-271	72	13	[	[	PUNCT
bioscience-271	72	14	21	21	NUM
bioscience-271	72	15	]	]	PUNCT
bioscience-271	72	16	.	.	PUNCT
bioscience-271	73	1	the	the	DET
bioscience-271	73	2	analysis	analysis	NOUN
bioscience-271	73	3	of	of	ADP
bioscience-271	73	4	oa	oa	PRON
bioscience-271	73	5	in	in	ADP
bioscience-271	73	6	medicated	medicate	VERB
bioscience-271	73	7	feed	feed	NOUN
bioscience-271	73	8	by	by	ADP
bioscience-271	73	9	liquid	liquid	ADJ
bioscience-271	73	10	chromatography	chromatography	NOUN
bioscience-271	73	11	-	-	PUNCT
bioscience-271	73	12	tandem	tandem	NOUN
bioscience-271	73	13	mass	mass	ADJ
bioscience-271	73	14	spectrometry	spectrometry	NOUN
bioscience-271	73	15	(	(	PUNCT
bioscience-271	73	16	lc	lc	PROPN
bioscience-271	73	17	-	-	PUNCT
bioscience-271	73	18	ms	ms	PROPN
bioscience-271	73	19	/	/	SYM
bioscience-271	73	20	ms	ms	NOUN
bioscience-271	73	21	)	)	PUNCT
bioscience-271	73	22	revealed	reveal	VERB
bioscience-271	73	23	96±1	96±1	NUM
bioscience-271	73	24	%	%	NOUN
bioscience-271	73	25	of	of	ADP
bioscience-271	73	26	the	the	DET
bioscience-271	73	27	incorporated	incorporated	ADJ
bioscience-271	73	28	dose	dose	NOUN
bioscience-271	73	29	[	[	X
bioscience-271	73	30	23	23	NUM
bioscience-271	73	31	]	]	PUNCT
bioscience-271	73	32	.	.	PUNCT
bioscience-271	74	1	the	the	DET
bioscience-271	74	2	efficacy	efficacy	NOUN
bioscience-271	74	3	study	study	NOUN
bioscience-271	74	4	utilized	utilize	VERB
bioscience-271	74	5	o.	o.	PROPN
bioscience-271	74	6	niloticus	niloticus	PROPN
bioscience-271	74	7	weighing	weigh	VERB
bioscience-271	74	8	17.56	17.56	NUM
bioscience-271	74	9	±	±	NUM
bioscience-271	74	10	0.89	0.89	NUM
bioscience-271	74	11	g	g	NOUN
bioscience-271	74	12	(	(	PUNCT
bioscience-271	74	13	n	n	NOUN
bioscience-271	74	14	=	=	NUM
bioscience-271	74	15	225	225	NUM
bioscience-271	74	16	)	)	PUNCT
bioscience-271	74	17	and	and	CCONJ
bioscience-271	74	18	distributed	distribute	VERB
bioscience-271	74	19	randomly	randomly	ADV
bioscience-271	74	20	in	in	ADP
bioscience-271	74	21	nine	nine	NUM
bioscience-271	74	22	thoroughly	thoroughly	ADV
bioscience-271	74	23	cleaned	clean	VERB
bioscience-271	74	24	polypropylene	polypropylene	NOUN
bioscience-271	74	25	tanks	tank	NOUN
bioscience-271	74	26	(	(	PUNCT
bioscience-271	74	27	l58	l58	VERB
bioscience-271	74	28	×	×	PROPN
bioscience-271	74	29	h45	h45	ADJ
bioscience-271	74	30	×	×	PROPN
bioscience-271	74	31	b45	b45	NOUN
bioscience-271	74	32	cm	cm	NOUN
bioscience-271	74	33	)	)	PUNCT
bioscience-271	74	34	.	.	PUNCT
bioscience-271	75	1	the	the	DET
bioscience-271	75	2	rearing	rear	VERB
bioscience-271	75	3	water	water	NOUN
bioscience-271	75	4	(	(	PUNCT
bioscience-271	75	5	80	80	NUM
bioscience-271	75	6	l	l	NOUN
bioscience-271	75	7	)	)	PUNCT
bioscience-271	75	8	in	in	ADP
bioscience-271	75	9	each	each	DET
bioscience-271	75	10	tank	tank	NOUN
bioscience-271	75	11	was	be	AUX
bioscience-271	75	12	conditioned	condition	VERB
bioscience-271	75	13	for	for	ADP
bioscience-271	75	14	three	three	NUM
bioscience-271	75	15	days	day	NOUN
bioscience-271	75	16	,	,	PUNCT
bioscience-271	75	17	stocked	stock	VERB
bioscience-271	75	18	with	with	ADP
bioscience-271	75	19	25	25	NUM
bioscience-271	75	20	accustomed	accustomed	ADJ
bioscience-271	75	21	tilapias	tilapia	NOUN
bioscience-271	75	22	,	,	PUNCT
bioscience-271	75	23	and	and	CCONJ
bioscience-271	75	24	properly	properly	ADV
bioscience-271	75	25	covered	cover	VERB
bioscience-271	75	26	and	and	CCONJ
bioscience-271	75	27	marked	mark	VERB
bioscience-271	75	28	.	.	PUNCT
bioscience-271	76	1	about	about	ADV
bioscience-271	76	2	half	half	NOUN
bioscience-271	76	3	of	of	ADP
bioscience-271	76	4	the	the	DET
bioscience-271	76	5	water	water	NOUN
bioscience-271	76	6	was	be	AUX
bioscience-271	76	7	exchanged	exchange	VERB
bioscience-271	76	8	to	to	PART
bioscience-271	76	9	remove	remove	VERB
bioscience-271	76	10	feed	feed	NOUN
bioscience-271	76	11	and	and	CCONJ
bioscience-271	76	12	faecal	faecal	ADJ
bioscience-271	76	13	wastes	waste	NOUN
bioscience-271	76	14	.	.	PUNCT
bioscience-271	77	1	the	the	DET
bioscience-271	77	2	fish	fish	NOUN
bioscience-271	77	3	stocks	stock	NOUN
bioscience-271	77	4	were	be	AUX
bioscience-271	77	5	divided	divide	VERB
bioscience-271	77	6	into	into	ADP
bioscience-271	77	7	three	three	NUM
bioscience-271	77	8	groups	group	NOUN
bioscience-271	77	9	,	,	PUNCT
bioscience-271	77	10	in	in	ADP
bioscience-271	77	11	triplicate	triplicate	NOUN
bioscience-271	77	12	.	.	PUNCT
bioscience-271	78	1	the	the	DET
bioscience-271	78	2	control	control	NOUN
bioscience-271	78	3	,	,	PUNCT
bioscience-271	78	4	designated	designate	VERB
bioscience-271	78	5	as	as	ADP
bioscience-271	78	6	group	group	NOUN
bioscience-271	78	7	1	1	NUM
bioscience-271	78	8	,	,	PUNCT
bioscience-271	78	9	received	receive	VERB
bioscience-271	78	10	a	a	DET
bioscience-271	78	11	0.1	0.1	NUM
bioscience-271	78	12	ml	ml	NOUN
bioscience-271	78	13	saline	saline	ADJ
bioscience-271	78	14	injection	injection	NOUN
bioscience-271	78	15	intramuscularly	intramuscularly	ADV
bioscience-271	78	16	at	at	ADP
bioscience-271	78	17	the	the	DET
bioscience-271	78	18	dorsal	dorsal	NOUN
bioscience-271	78	19	fin	fin	NOUN
bioscience-271	78	20	base	base	NOUN
bioscience-271	78	21	.	.	PUNCT
bioscience-271	79	1	all	all	DET
bioscience-271	79	2	fish	fish	NOUN
bioscience-271	79	3	of	of	ADP
bioscience-271	79	4	groups	group	NOUN
bioscience-271	79	5	2	2	NUM
bioscience-271	79	6	and	and	CCONJ
bioscience-271	79	7	3	3	NUM
bioscience-271	79	8	were	be	AUX
bioscience-271	79	9	injected	inject	VERB
bioscience-271	79	10	intramuscularly	intramuscularly	ADV
bioscience-271	79	11	with	with	ADP
bioscience-271	79	12	s.	s.	PROPN
bioscience-271	79	13	agalactiae	agalactiae	PROPN
bioscience-271	79	14	lcr1	lcr1	PROPN
bioscience-271	79	15	at	at	ADP
bioscience-271	79	16	1.32	1.32	NUM
bioscience-271	79	17	×	×	NOUN
bioscience-271	79	18	107	107	NUM
bioscience-271	79	19	cells	cell	NOUN
bioscience-271	79	20	/	/	SYM
bioscience-271	79	21	fish	fish	NOUN
bioscience-271	79	22	.	.	PUNCT
bioscience-271	80	1	post	post	ADJ
bioscience-271	80	2	-	-	NOUN
bioscience-271	80	3	injection	injection	NOUN
bioscience-271	80	4	,	,	PUNCT
bioscience-271	80	5	the	the	DET
bioscience-271	80	6	fish	fish	NOUN
bioscience-271	80	7	were	be	AUX
bioscience-271	80	8	placed	place	VERB
bioscience-271	80	9	in	in	ADP
bioscience-271	80	10	their	their	PRON
bioscience-271	80	11	respective	respective	ADJ
bioscience-271	80	12	tanks	tank	NOUN
bioscience-271	80	13	.	.	PUNCT
bioscience-271	81	1	control	control	NOUN
bioscience-271	81	2	feed	feed	NOUN
bioscience-271	81	3	was	be	AUX
bioscience-271	81	4	offered	offer	VERB
bioscience-271	81	5	to	to	ADP
bioscience-271	81	6	groups	group	NOUN
bioscience-271	81	7	1	1	NUM
bioscience-271	81	8	and	and	CCONJ
bioscience-271	81	9	3	3	NUM
bioscience-271	81	10	throughout	throughout	ADP
bioscience-271	81	11	the	the	DET
bioscience-271	81	12	experimental	experimental	ADJ
bioscience-271	81	13	period	period	NOUN
bioscience-271	81	14	of	of	ADP
bioscience-271	81	15	21	21	NUM
bioscience-271	81	16	days	day	NOUN
bioscience-271	81	17	.	.	PUNCT
bioscience-271	82	1	oa	oa	VERB
bioscience-271	82	2	-	-	PUNCT
bioscience-271	82	3	medicated	medicate	VERB
bioscience-271	82	4	feed	feed	NOUN
bioscience-271	82	5	at	at	ADP
bioscience-271	82	6	2	2	NUM
bioscience-271	82	7	%	%	NOUN
bioscience-271	82	8	bw	bw	NOUN
bioscience-271	82	9	was	be	AUX
bioscience-271	82	10	served	serve	VERB
bioscience-271	82	11	to	to	ADP
bioscience-271	82	12	group	group	NOUN
bioscience-271	82	13	2	2	NUM
bioscience-271	82	14	continuously	continuously	ADV
bioscience-271	82	15	for	for	ADP
bioscience-271	82	16	7	7	NUM
bioscience-271	82	17	days	day	NOUN
bioscience-271	82	18	post	post	ADJ
bioscience-271	82	19	-	-	NOUN
bioscience-271	82	20	injection	injection	ADJ
bioscience-271	82	21	(	(	PUNCT
bioscience-271	82	22	dpi	dpi	NOUN
bioscience-271	82	23	)	)	PUNCT
bioscience-271	82	24	and	and	CCONJ
bioscience-271	82	25	then	then	ADV
bioscience-271	82	26	switched	switch	VERB
bioscience-271	82	27	to	to	ADP
bioscience-271	82	28	a	a	DET
bioscience-271	82	29	control	control	NOUN
bioscience-271	82	30	feed	feed	NOUN
bioscience-271	82	31	[	[	X
bioscience-271	82	32	21	21	NUM
bioscience-271	82	33	;	;	PUNCT
bioscience-271	82	34	23	23	NUM
bioscience-271	82	35	]	]	PUNCT
bioscience-271	82	36	.	.	PUNCT
bioscience-271	83	1	water	water	NOUN
bioscience-271	83	2	quality	quality	NOUN
bioscience-271	83	3	was	be	AUX
bioscience-271	83	4	continuously	continuously	ADV
bioscience-271	83	5	monitored	monitor	VERB
bioscience-271	83	6	,	,	PUNCT
bioscience-271	83	7	and	and	CCONJ
bioscience-271	83	8	any	any	DET
bioscience-271	83	9	leftover	leftover	NOUN
bioscience-271	83	10	feed	feed	NOUN
bioscience-271	83	11	,	,	PUNCT
bioscience-271	83	12	if	if	SCONJ
bioscience-271	83	13	any	any	PRON
bioscience-271	83	14	,	,	PUNCT
bioscience-271	83	15	was	be	AUX
bioscience-271	83	16	removed	remove	VERB
bioscience-271	83	17	1	1	NUM
bioscience-271	83	18	hour	hour	NOUN
bioscience-271	83	19	after	after	ADP
bioscience-271	83	20	each	each	DET
bioscience-271	83	21	feeding	feeding	NOUN
bioscience-271	83	22	.	.	PUNCT
bioscience-271	84	1	observations	observation	NOUN
bioscience-271	84	2	on	on	ADP
bioscience-271	84	3	mortality	mortality	NOUN
bioscience-271	84	4	,	,	PUNCT
bioscience-271	84	5	infection	infection	NOUN
bioscience-271	84	6	symptoms	symptom	NOUN
bioscience-271	84	7	,	,	PUNCT
bioscience-271	84	8	and	and	CCONJ
bioscience-271	84	9	behaviour	behaviour	NOUN
bioscience-271	84	10	were	be	AUX
bioscience-271	84	11	recorded	record	VERB
bioscience-271	84	12	daily	daily	ADV
bioscience-271	84	13	.	.	PUNCT
bioscience-271	85	1	inocula	inocula	VERB
bioscience-271	85	2	from	from	ADP
bioscience-271	85	3	the	the	DET
bioscience-271	85	4	freshly	freshly	ADV
bioscience-271	85	5	dead	dead	ADJ
bioscience-271	85	6	figure	figure	NOUN
bioscience-271	85	7	3	3	NUM
bioscience-271	85	8	.	.	PUNCT
bioscience-271	86	1	the	the	DET
bioscience-271	86	2	histopathological	histopathological	ADJ
bioscience-271	86	3	changes	change	NOUN
bioscience-271	86	4	in	in	ADP
bioscience-271	86	5	the	the	DET
bioscience-271	86	6	granular	granular	ADJ
bioscience-271	86	7	cell	cell	NOUN
bioscience-271	86	8	layer	layer	NOUN
bioscience-271	86	9	of	of	ADP
bioscience-271	86	10	the	the	DET
bioscience-271	86	11	cerebellum	cerebellum	ADJ
bioscience-271	86	12	(	(	PUNCT
bioscience-271	86	13	gic	gic	NOUN
bioscience-271	86	14	)	)	PUNCT
bioscience-271	86	15	of	of	ADP
bioscience-271	86	16	the	the	DET
bioscience-271	86	17	brain	brain	NOUN
bioscience-271	86	18	of	of	ADP
bioscience-271	86	19	streptococcus	streptococcus	NOUN
bioscience-271	86	20	agalactiae	agalactiae	PROPN
bioscience-271	86	21	lcr1	lcr1	PROPN
bioscience-271	86	22	challenged	challenge	VERB
bioscience-271	86	23	and	and	CCONJ
bioscience-271	86	24	oxolinic	oxolinic	ADJ
bioscience-271	86	25	acid	acid	NOUN
bioscience-271	86	26	(	(	PUNCT
bioscience-271	86	27	oa	oa	INTJ
bioscience-271	86	28	)	)	PUNCT
bioscience-271	86	29	treated	treat	VERB
bioscience-271	86	30	and	and	CCONJ
bioscience-271	86	31	untreated	untreate	VERB
bioscience-271	86	32	oreochromis	oreochromis	PROPN
bioscience-271	86	33	niloticus	niloticus	PROPN
bioscience-271	86	34	juveniles	juvenile	NOUN
bioscience-271	86	35	.	.	PUNCT
bioscience-271	87	1	[	[	X
bioscience-271	87	2	a	a	X
bioscience-271	87	3	]	]	X
bioscience-271	87	4	control	control	NOUN
bioscience-271	87	5	,	,	PUNCT
bioscience-271	87	6	[	[	X
bioscience-271	87	7	b	b	X
bioscience-271	87	8	]	]	X
bioscience-271	87	9	day	day	NOUN
bioscience-271	87	10	post	post	NOUN
bioscience-271	87	11	-	-	NOUN
bioscience-271	87	12	injection	injection	ADJ
bioscience-271	87	13	(	(	PUNCT
bioscience-271	87	14	dpi	dpi	NOUN
bioscience-271	87	15	)	)	PUNCT
bioscience-271	87	16	1	1	NUM
bioscience-271	87	17	oa	oa	PRON
bioscience-271	87	18	treated	treat	VERB
bioscience-271	87	19	and	and	CCONJ
bioscience-271	87	20	[	[	X
bioscience-271	87	21	c	c	X
bioscience-271	87	22	]	]	X
bioscience-271	87	23	untreated	untreated	ADJ
bioscience-271	87	24	;	;	PUNCT
bioscience-271	87	25	[	[	X
bioscience-271	87	26	d	d	X
bioscience-271	87	27	]	]	X
bioscience-271	87	28	dpi	dpi	NOUN
bioscience-271	87	29	7	7	NUM
bioscience-271	87	30	oa	oa	NOUN
bioscience-271	87	31	treated	treat	VERB
bioscience-271	87	32	and	and	CCONJ
bioscience-271	87	33	[	[	X
bioscience-271	87	34	e	e	X
bioscience-271	87	35	]	]	X
bioscience-271	87	36	untreated	untreated	ADJ
bioscience-271	87	37	;	;	PUNCT
bioscience-271	87	38	[	[	X
bioscience-271	87	39	f	f	X
bioscience-271	87	40	]	]	X
bioscience-271	87	41	dpi	dpi	NOUN
bioscience-271	87	42	14	14	NUM
bioscience-271	87	43	oa	oa	NUM
bioscience-271	87	44	treated	treat	VERB
bioscience-271	87	45	and	and	CCONJ
bioscience-271	87	46	[	[	X
bioscience-271	87	47	g	g	X
bioscience-271	87	48	]	]	PUNCT
bioscience-271	87	49	untreated	untreated	ADJ
bioscience-271	87	50	;	;	PUNCT
bioscience-271	87	51	and	and	CCONJ
bioscience-271	87	52	[	[	X
bioscience-271	87	53	h	h	X
bioscience-271	87	54	]	]	X
bioscience-271	87	55	dpi	dpi	NOUN
bioscience-271	87	56	21	21	NUM
bioscience-271	87	57	oa	oa	PRON
bioscience-271	87	58	treated	treat	VERB
bioscience-271	88	1	and	and	CCONJ
bioscience-271	88	2	[	[	X
bioscience-271	88	3	i	i	X
bioscience-271	88	4	]	]	PUNCT
bioscience-271	88	5	untreated	untreated	ADJ
bioscience-271	88	6	.	.	PUNCT
bioscience-271	89	1	lse	lse	PROPN
bioscience-271	89	2	:	:	PUNCT
bioscience-271	89	3	localized	localized	ADJ
bioscience-271	89	4	spongiform	spongiform	NOUN
bioscience-271	89	5	encephalopathy	encephalopathy	NOUN
bioscience-271	89	6	;	;	PUNCT
bioscience-271	89	7	v	v	NOUN
bioscience-271	89	8	:	:	PUNCT
bioscience-271	89	9	vacuolation	vacuolation	NOUN
bioscience-271	89	10	;	;	PUNCT
bioscience-271	89	11	lgc	lgc	ADJ
bioscience-271	89	12	:	:	PUNCT
bioscience-271	89	13	lysis	lysis	NOUN
bioscience-271	89	14	of	of	ADP
bioscience-271	89	15	granular	granular	ADJ
bioscience-271	89	16	cells	cell	NOUN
bioscience-271	89	17	of	of	ADP
bioscience-271	89	18	the	the	DET
bioscience-271	89	19	cerebellum	cerebellum	NOUN
bioscience-271	89	20	;	;	PUNCT
bioscience-271	89	21	and	and	CCONJ
bioscience-271	89	22	n	n	CCONJ
bioscience-271	89	23	:	:	PUNCT
bioscience-271	89	24	necrotised	necrotise	VERB
bioscience-271	89	25	area	area	NOUN
bioscience-271	89	26	x200	x200	PROPN
bioscience-271	89	27	,	,	PUNCT
bioscience-271	89	28	h&e	h&e	PROPN
bioscience-271	89	29	staining	staining	NOUN
bioscience-271	89	30	.	.	PUNCT
bioscience-271	90	1	sa	sa	VERB
bioscience-271	90	2	-	-	PUNCT
bioscience-271	90	3	challenged	challenge	VERB
bioscience-271	90	4	tilapia	tilapia	NOUN
bioscience-271	90	5	brain	brain	NOUN
bioscience-271	90	6	were	be	AUX
bioscience-271	90	7	plated	plate	VERB
bioscience-271	90	8	onto	onto	ADP
bioscience-271	90	9	bhia	bhia	NOUN
bioscience-271	90	10	to	to	PART
bioscience-271	90	11	establish	establish	VERB
bioscience-271	90	12	sa	sa	NOUN
bioscience-271	90	13	-	-	PUNCT
bioscience-271	90	14	infection	infection	NOUN
bioscience-271	90	15	[	[	X
bioscience-271	90	16	5	5	NUM
bioscience-271	90	17	]	]	PUNCT
bioscience-271	90	18	.	.	PUNCT
bioscience-271	91	1	histopathology	histopathology	NOUN
bioscience-271	91	2	and	and	CCONJ
bioscience-271	91	3	evaluation	evaluation	NOUN
bioscience-271	91	4	of	of	ADP
bioscience-271	91	5	pathological	pathological	ADJ
bioscience-271	91	6	anomalies	anomaly	NOUN
bioscience-271	91	7	on	on	ADP
bioscience-271	91	8	0	0	NUM
bioscience-271	91	9	,	,	PUNCT
bioscience-271	91	10	1	1	NUM
bioscience-271	91	11	,	,	PUNCT
bioscience-271	91	12	7	7	NUM
bioscience-271	91	13	,	,	PUNCT
bioscience-271	91	14	14	14	NUM
bioscience-271	91	15	,	,	PUNCT
bioscience-271	91	16	and	and	CCONJ
bioscience-271	91	17	21	21	NUM
bioscience-271	91	18	dpi	dpi	NOUN
bioscience-271	91	19	,	,	PUNCT
bioscience-271	91	20	two	two	NUM
bioscience-271	91	21	fish	fish	NOUN
bioscience-271	91	22	were	be	AUX
bioscience-271	91	23	randomly	randomly	ADV
bioscience-271	91	24	sampled	sample	VERB
bioscience-271	91	25	from	from	ADP
bioscience-271	91	26	each	each	DET
bioscience-271	91	27	replicate	replicate	ADJ
bioscience-271	91	28	tank	tank	NOUN
bioscience-271	91	29	,	,	PUNCT
bioscience-271	91	30	euthanized	euthanize	VERB
bioscience-271	91	31	by	by	ADP
bioscience-271	91	32	adding	add	VERB
bioscience-271	91	33	clove	clove	NOUN
bioscience-271	91	34	oil	oil	NOUN
bioscience-271	91	35	at	at	ADP
bioscience-271	91	36	100	100	NUM
bioscience-271	91	37	µl	µl	ADP
bioscience-271	91	38	/	/	SYM
bioscience-271	91	39	l	l	NOUN
bioscience-271	91	40	,	,	PUNCT
bioscience-271	91	41	and	and	CCONJ
bioscience-271	91	42	dissected	dissect	VERB
bioscience-271	91	43	prudently	prudently	ADV
bioscience-271	91	44	.	.	PUNCT
bioscience-271	92	1	the	the	DET
bioscience-271	92	2	cranial	cranial	ADJ
bioscience-271	92	3	bone	bone	NOUN
bioscience-271	92	4	was	be	AUX
bioscience-271	92	5	removed	remove	VERB
bioscience-271	92	6	carefully	carefully	ADV
bioscience-271	92	7	to	to	PART
bioscience-271	92	8	expose	expose	VERB
bioscience-271	92	9	the	the	DET
bioscience-271	92	10	brain	brain	NOUN
bioscience-271	92	11	.	.	PUNCT
bioscience-271	93	1	the	the	DET
bioscience-271	93	2	precisely	precisely	ADV
bioscience-271	93	3	collected	collect	VERB
bioscience-271	93	4	wholebrain	wholebrain	ADJ
bioscience-271	93	5	tissue	tissue	NOUN
bioscience-271	93	6	samples	sample	NOUN
bioscience-271	93	7	were	be	AUX
bioscience-271	93	8	fixed	fix	VERB
bioscience-271	93	9	for	for	ADP
bioscience-271	93	10	24	24	NUM
bioscience-271	93	11	hours	hour	NOUN
bioscience-271	93	12	in	in	ADP
bioscience-271	93	13	bouin	bouin	NOUN
bioscience-271	93	14	’s	’s	PART
bioscience-271	93	15	fixative	fixative	ADJ
bioscience-271	93	16	,	,	PUNCT
bioscience-271	93	17	processed	process	VERB
bioscience-271	93	18	,	,	PUNCT
bioscience-271	93	19	and	and	CCONJ
bioscience-271	93	20	embedded	embed	VERB
bioscience-271	93	21	in	in	ADP
bioscience-271	93	22	paraffin	paraffin	NOUN
bioscience-271	93	23	wax	wax	NOUN
bioscience-271	93	24	.	.	PUNCT
bioscience-271	94	1	sections	section	NOUN
bioscience-271	94	2	of	of	ADP
bioscience-271	94	3	5	5	NUM
bioscience-271	94	4	µm	µm	NOUN
bioscience-271	94	5	thickness	thickness	NOUN
bioscience-271	94	6	were	be	AUX
bioscience-271	94	7	sliced	slice	VERB
bioscience-271	94	8	,	,	PUNCT
bioscience-271	94	9	processed	process	VERB
bioscience-271	94	10	,	,	PUNCT
bioscience-271	94	11	and	and	CCONJ
bioscience-271	94	12	double	double	ADJ
bioscience-271	94	13	-	-	PUNCT
bioscience-271	94	14	stained	stained	ADJ
bioscience-271	94	15	using	use	VERB
bioscience-271	94	16	hematoxylin	hematoxylin	NOUN
bioscience-271	94	17	and	and	CCONJ
bioscience-271	94	18	eosin	eosin	NOUN
bioscience-271	94	19	[	[	X
bioscience-271	94	20	33	33	NUM
bioscience-271	94	21	]	]	PUNCT
bioscience-271	94	22	.	.	PUNCT
bioscience-271	95	1	the	the	DET
bioscience-271	95	2	brain	brain	NOUN
bioscience-271	95	3	sections	section	NOUN
bioscience-271	95	4	were	be	AUX
bioscience-271	95	5	examined	examine	VERB
bioscience-271	95	6	under	under	ADP
bioscience-271	95	7	an	an	DET
bioscience-271	95	8	olympus	olympus	PROPN
bioscience-271	95	9	microscope	microscope	NOUN
bioscience-271	95	10	(	(	PUNCT
bioscience-271	95	11	model	model	NOUN
bioscience-271	95	12	:	:	PUNCT
bioscience-271	95	13	bx51	bx51	PROPN
bioscience-271	95	14	)	)	PUNCT
bioscience-271	95	15	at	at	ADP
bioscience-271	95	16	20×	20×	NUM
bioscience-271	95	17	magnification	magnification	NOUN
bioscience-271	95	18	to	to	PART
bioscience-271	95	19	identify	identify	VERB
bioscience-271	95	20	abnormalities	abnormality	NOUN
bioscience-271	95	21	in	in	ADP
bioscience-271	95	22	tissue	tissue	NOUN
bioscience-271	95	23	arrangement	arrangement	NOUN
bioscience-271	95	24	.	.	PUNCT
bioscience-271	96	1	for	for	ADP
bioscience-271	96	2	quantitative	quantitative	ADJ
bioscience-271	96	3	analysis	analysis	NOUN
bioscience-271	96	4	,	,	PUNCT
bioscience-271	96	5	images	image	NOUN
bioscience-271	96	6	were	be	AUX
bioscience-271	96	7	captured	capture	VERB
bioscience-271	96	8	and	and	CCONJ
bioscience-271	96	9	processed	process	VERB
bioscience-271	96	10	using	use	VERB
bioscience-271	96	11	an	an	DET
bioscience-271	96	12	scolux	scolux	NOUN
bioscience-271	96	13	camera	camera	NOUN
bioscience-271	96	14	(	(	PUNCT
bioscience-271	96	15	16	16	NUM
bioscience-271	96	16	mp	mp	NOUN
bioscience-271	96	17	)	)	PUNCT
bioscience-271	96	18	and	and	CCONJ
bioscience-271	96	19	touptek	touptek	NOUN
bioscience-271	96	20	toupview	toupview	NOUN
bioscience-271	96	21	software	software	NOUN
bioscience-271	96	22	(	(	PUNCT
bioscience-271	96	23	version	version	NOUN
bioscience-271	96	24	x64	x64	PROPN
bioscience-271	96	25	)	)	PUNCT
bioscience-271	96	26	.	.	PUNCT
bioscience-271	97	1	the	the	DET
bioscience-271	97	2	histopathological	histopathological	ADJ
bioscience-271	97	3	abnormalities	abnormality	NOUN
bioscience-271	97	4	were	be	AUX
bioscience-271	97	5	evaluated	evaluate	VERB
bioscience-271	97	6	based	base	VERB
bioscience-271	97	7	on	on	ADP
bioscience-271	97	8	circulatory	circulatory	ADJ
bioscience-271	97	9	,	,	PUNCT
bioscience-271	97	10	progressive	progressive	ADJ
bioscience-271	97	11	,	,	PUNCT
bioscience-271	97	12	regressive	regressive	ADJ
bioscience-271	97	13	,	,	PUNCT
bioscience-271	97	14	and	and	CCONJ
bioscience-271	97	15	inflammatory	inflammatory	ADJ
bioscience-271	97	16	changes	change	NOUN
bioscience-271	97	17	.	.	PUNCT
bioscience-271	98	1	following	follow	VERB
bioscience-271	98	2	the	the	DET
bioscience-271	98	3	observations	observation	NOUN
bioscience-271	98	4	,	,	PUNCT
bioscience-271	98	5	reaction	reaction	NOUN
bioscience-271	98	6	indices	index	NOUN
bioscience-271	98	7	(	(	PUNCT
bioscience-271	98	8	ri	ri	NOUN
bioscience-271	98	9	)	)	PUNCT
bioscience-271	98	10	were	be	AUX
bioscience-271	98	11	calculated	calculate	VERB
bioscience-271	98	12	as	as	ADP
bioscience-271	98	13	a	a	DET
bioscience-271	98	14	product	product	NOUN
bioscience-271	98	15	of	of	ADP
bioscience-271	98	16	the	the	DET
bioscience-271	98	17	score	score	NOUN
bioscience-271	98	18	value	value	NOUN
bioscience-271	98	19	and	and	CCONJ
bioscience-271	98	20	the	the	DET
bioscience-271	98	21	importance	importance	NOUN
bioscience-271	98	22	factor	factor	NOUN
bioscience-271	98	23	.	.	PUNCT
bioscience-271	99	1	the	the	DET
bioscience-271	99	2	score	score	NOUN
bioscience-271	99	3	value	value	NOUN
bioscience-271	99	4	,	,	PUNCT
bioscience-271	99	5	ranging	range	VERB
bioscience-271	99	6	from	from	ADP
bioscience-271	99	7	0	0	NUM
bioscience-271	99	8	to	to	ADP
bioscience-271	99	9	6	6	NUM
bioscience-271	99	10	,	,	PUNCT
bioscience-271	99	11	was	be	AUX
bioscience-271	99	12	assigned	assign	VERB
bioscience-271	99	13	based	base	VERB
bioscience-271	99	14	on	on	ADP
bioscience-271	99	15	the	the	DET
bioscience-271	99	16	severity	severity	NOUN
bioscience-271	99	17	and	and	CCONJ
bioscience-271	99	18	degree	degree	NOUN
bioscience-271	99	19	of	of	ADP
bioscience-271	99	20	damage	damage	NOUN
bioscience-271	99	21	:	:	PUNCT
bioscience-271	99	22	no	no	DET
bioscience-271	99	23	change	change	NOUN
bioscience-271	99	24	(	(	PUNCT
bioscience-271	99	25	0	0	NUM
bioscience-271	99	26	)	)	PUNCT
bioscience-271	99	27	,	,	PUNCT
bioscience-271	99	28	mild	mild	ADJ
bioscience-271	99	29	occurrence	occurrence	NOUN
bioscience-271	99	30	(	(	PUNCT
bioscience-271	99	31	2	2	NUM
bioscience-271	99	32	)	)	PUNCT
bioscience-271	99	33	,	,	PUNCT
bioscience-271	99	34	moderate	moderate	ADJ
bioscience-271	99	35	occurrence	occurrence	NOUN
bioscience-271	99	36	(	(	PUNCT
bioscience-271	99	37	4	4	NUM
bioscience-271	99	38	)	)	PUNCT
bioscience-271	99	39	,	,	PUNCT
bioscience-271	99	40	and	and	CCONJ
bioscience-271	99	41	severe	severe	ADJ
bioscience-271	99	42	occurrence	occurrence	NOUN
bioscience-271	99	43	(	(	PUNCT
bioscience-271	99	44	6	6	NUM
bioscience-271	99	45	)	)	PUNCT
bioscience-271	99	46	.	.	PUNCT
bioscience-271	100	1	the	the	DET
bioscience-271	100	2	importance	importance	NOUN
bioscience-271	100	3	factor	factor	NOUN
bioscience-271	100	4	,	,	PUNCT
bioscience-271	100	5	ranging	range	VERB
bioscience-271	100	6	from	from	ADP
bioscience-271	100	7	1	1	NUM
bioscience-271	100	8	to	to	ADP
bioscience-271	100	9	3	3	NUM
bioscience-271	100	10	,	,	PUNCT
bioscience-271	100	11	was	be	AUX
bioscience-271	100	12	assigned	assign	VERB
bioscience-271	100	13	based	base	VERB
bioscience-271	100	14	on	on	ADP
bioscience-271	100	15	the	the	DET
bioscience-271	100	16	pathological	pathological	ADJ
bioscience-271	100	17	significance	significance	NOUN
bioscience-271	100	18	of	of	ADP
bioscience-271	100	19	each	each	DET
bioscience-271	100	20	alteration	alteration	NOUN
bioscience-271	100	21	,	,	PUNCT
bioscience-271	100	22	categorized	categorize	VERB
bioscience-271	100	23	1	1	NUM
bioscience-271	100	24	:	:	PUNCT
bioscience-271	100	25	minimal	minimal	ADJ
bioscience-271	100	26	pathological	pathological	ADJ
bioscience-271	100	27	importance	importance	NOUN
bioscience-271	100	28	,	,	PUNCT
bioscience-271	100	29	easily	easily	ADV
bioscience-271	100	30	reversible	reversible	ADJ
bioscience-271	100	31	post	post	ADJ
bioscience-271	100	32	-	-	ADJ
bioscience-271	100	33	stressor	stressor	ADJ
bioscience-271	100	34	highlights	highlight	NOUN
bioscience-271	100	35	in	in	ADP
bioscience-271	100	36	bioscience	bioscience	NOUN
bioscience-271	100	37	page	page	NOUN
bioscience-271	100	38	3	3	NUM
bioscience-271	100	39	of	of	ADP
bioscience-271	100	40	10	10	NUM
bioscience-271	100	41	october	october	PROPN
bioscience-271	100	42	2025|volume	2025|volume	NUM
bioscience-271	100	43	8	8	NUM
bioscience-271	100	44	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	100	45	sinha	sinha	PROPN
bioscience-271	100	46	p	p	PROPN
bioscience-271	100	47	et	et	PROPN
bioscience-271	100	48	al	al	PROPN
bioscience-271	100	49	.	.	PROPN
bioscience-271	100	50	,	,	PUNCT
bioscience-271	100	51	2025	2025	NUM
bioscience-271	100	52	effect	effect	NOUN
bioscience-271	100	53	of	of	ADP
bioscience-271	100	54	oxolinic	oxolinic	ADJ
bioscience-271	100	55	acid	acid	NOUN
bioscience-271	100	56	therapy	therapy	NOUN
bioscience-271	100	57	figure	figure	NOUN
bioscience-271	100	58	4	4	NUM
bioscience-271	100	59	.	.	PUNCT
bioscience-271	100	60	homology	homology	NOUN
bioscience-271	100	61	modelled	model	VERB
bioscience-271	100	62	3d	3d	NUM
bioscience-271	100	63	structures	structure	NOUN
bioscience-271	100	64	[	[	X
bioscience-271	100	65	a1	a1	NOUN
bioscience-271	100	66	and	and	CCONJ
bioscience-271	100	67	b1	b1	NOUN
bioscience-271	100	68	]	]	PUNCT
bioscience-271	100	69	and	and	CCONJ
bioscience-271	100	70	ramachandran	ramachandran	NOUN
bioscience-271	100	71	plots	plot	NOUN
bioscience-271	101	1	[	[	X
bioscience-271	101	2	a2	a2	NOUN
bioscience-271	101	3	and	and	CCONJ
bioscience-271	101	4	b2	b2	NOUN
bioscience-271	101	5	]	]	PUNCT
bioscience-271	101	6	of	of	ADP
bioscience-271	101	7	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	101	8	(	(	PUNCT
bioscience-271	101	9	aam99596	aam99596	NOUN
bioscience-271	101	10	)	)	PUNCT
bioscience-271	101	11	and	and	CCONJ
bioscience-271	101	12	camp	camp	NOUN
bioscience-271	101	13	factor	factor	NOUN
bioscience-271	101	14	(	(	PUNCT
bioscience-271	101	15	aki96324	aki96324	ADJ
bioscience-271	101	16	)	)	PUNCT
bioscience-271	101	17	of	of	ADP
bioscience-271	101	18	streptococcus	streptococcus	NOUN
bioscience-271	101	19	agalactiae	agalactiae	NOUN
bioscience-271	101	20	,	,	PUNCT
bioscience-271	101	21	respectively	respectively	ADV
bioscience-271	101	22	,	,	PUNCT
bioscience-271	101	23	computed	compute	VERB
bioscience-271	101	24	using	use	VERB
bioscience-271	101	25	swissmodel	swissmodel	NOUN
bioscience-271	101	26	.	.	PUNCT
bioscience-271	102	1	administration	administration	NOUN
bioscience-271	102	2	,	,	PUNCT
bioscience-271	102	3	2	2	NUM
bioscience-271	102	4	:	:	PUNCT
bioscience-271	102	5	moderate	moderate	ADJ
bioscience-271	102	6	pathological	pathological	ADJ
bioscience-271	102	7	importance	importance	NOUN
bioscience-271	102	8	,	,	PUNCT
bioscience-271	102	9	reversible	reversible	ADJ
bioscience-271	102	10	if	if	SCONJ
bioscience-271	102	11	the	the	DET
bioscience-271	102	12	stressor	stressor	NOUN
bioscience-271	102	13	is	be	AUX
bioscience-271	102	14	neutralized	neutralize	VERB
bioscience-271	102	15	,	,	PUNCT
bioscience-271	102	16	3	3	NUM
bioscience-271	102	17	:	:	PUNCT
bioscience-271	102	18	marked	mark	VERB
bioscience-271	102	19	pathological	pathological	ADJ
bioscience-271	102	20	importance	importance	NOUN
bioscience-271	102	21	,	,	PUNCT
bioscience-271	102	22	generally	generally	ADV
bioscience-271	102	23	irreversible	irreversible	ADJ
bioscience-271	102	24	with	with	ADP
bioscience-271	102	25	potential	potential	ADJ
bioscience-271	102	26	loss	loss	NOUN
bioscience-271	102	27	of	of	ADP
bioscience-271	102	28	organ	organ	NOUN
bioscience-271	102	29	function	function	NOUN
bioscience-271	102	30	.	.	PUNCT
bioscience-271	103	1	for	for	ADP
bioscience-271	103	2	instance	instance	NOUN
bioscience-271	103	3	,	,	PUNCT
bioscience-271	103	4	for	for	ADP
bioscience-271	103	5	mild	mild	ADJ
bioscience-271	103	6	vacuolation	vacuolation	NOUN
bioscience-271	103	7	,	,	PUNCT
bioscience-271	103	8	which	which	PRON
bioscience-271	103	9	has	have	VERB
bioscience-271	103	10	a	a	DET
bioscience-271	103	11	pathological	pathological	ADJ
bioscience-271	103	12	importance	importance	NOUN
bioscience-271	103	13	factor	factor	NOUN
bioscience-271	103	14	of	of	ADP
bioscience-271	103	15	2	2	NUM
bioscience-271	103	16	,	,	PUNCT
bioscience-271	103	17	and	and	CCONJ
bioscience-271	103	18	an	an	DET
bioscience-271	103	19	observed	observed	ADJ
bioscience-271	103	20	severity	severity	NOUN
bioscience-271	103	21	score	score	NOUN
bioscience-271	103	22	of	of	ADP
bioscience-271	103	23	1.65	1.65	NUM
bioscience-271	103	24	depending	depend	VERB
bioscience-271	103	25	on	on	ADP
bioscience-271	103	26	damage	damage	NOUN
bioscience-271	103	27	intensity	intensity	NOUN
bioscience-271	103	28	,	,	PUNCT
bioscience-271	103	29	the	the	DET
bioscience-271	103	30	ri	ri	PROPN
bioscience-271	103	31	would	would	AUX
bioscience-271	103	32	be	be	AUX
bioscience-271	103	33	3.30	3.30	NUM
bioscience-271	103	34	(	(	PUNCT
bioscience-271	103	35	i.e.	i.e.	X
bioscience-271	103	36	,	,	PUNCT
bioscience-271	103	37	1.65	1.65	NUM
bioscience-271	103	38	×	×	NOUN
bioscience-271	103	39	2	2	NUM
bioscience-271	103	40	)	)	PUNCT
bioscience-271	103	41	.	.	PUNCT
bioscience-271	104	1	alterations	alteration	NOUN
bioscience-271	104	2	with	with	ADP
bioscience-271	104	3	a	a	DET
bioscience-271	104	4	higher	high	ADJ
bioscience-271	104	5	ri	ri	NOUN
bioscience-271	104	6	value	value	NOUN
bioscience-271	104	7	signified	signify	VERB
bioscience-271	104	8	greater	great	ADJ
bioscience-271	104	9	severity	severity	NOUN
bioscience-271	104	10	[	[	X
bioscience-271	104	11	34	34	NUM
bioscience-271	104	12	]	]	PUNCT
bioscience-271	104	13	.	.	PUNCT
bioscience-271	105	1	the	the	DET
bioscience-271	105	2	qualitative	qualitative	ADJ
bioscience-271	105	3	scores	score	NOUN
bioscience-271	105	4	of	of	ADP
bioscience-271	105	5	the	the	DET
bioscience-271	105	6	brain	brain	NOUN
bioscience-271	105	7	histological	histological	ADJ
bioscience-271	105	8	changes	change	NOUN
bioscience-271	105	9	,	,	PUNCT
bioscience-271	105	10	expressed	express	VERB
bioscience-271	105	11	as	as	ADP
bioscience-271	105	12	mean	mean	NOUN
bioscience-271	105	13	±	±	NUM
bioscience-271	105	14	standard	standard	ADJ
bioscience-271	105	15	deviation	deviation	NOUN
bioscience-271	105	16	of	of	ADP
bioscience-271	105	17	six	six	NUM
bioscience-271	105	18	observations	observation	NOUN
bioscience-271	105	19	,	,	PUNCT
bioscience-271	105	20	were	be	AUX
bioscience-271	105	21	analysed	analyse	VERB
bioscience-271	105	22	by	by	ADP
bioscience-271	105	23	a	a	DET
bioscience-271	105	24	non	non	ADJ
bioscience-271	105	25	-	-	ADJ
bioscience-271	105	26	parametric	parametric	ADJ
bioscience-271	105	27	kruskal	kruskal	PROPN
bioscience-271	105	28	–	–	PUNCT
bioscience-271	105	29	wallis	wallis	PROPN
bioscience-271	105	30	test	test	NOUN
bioscience-271	105	31	.	.	PUNCT
bioscience-271	106	1	the	the	DET
bioscience-271	106	2	mann	mann	PROPN
bioscience-271	106	3	–	–	PUNCT
bioscience-271	106	4	whitney	whitney	PROPN
bioscience-271	106	5	u	u	PROPN
bioscience-271	106	6	test	test	NOUN
bioscience-271	106	7	was	be	AUX
bioscience-271	106	8	conducted	conduct	VERB
bioscience-271	106	9	for	for	ADP
bioscience-271	106	10	pairwise	pairwise	NOUN
bioscience-271	106	11	comparisons	comparison	NOUN
bioscience-271	106	12	in	in	ADP
bioscience-271	106	13	ibm	ibm	PROPN
bioscience-271	106	14	-	-	PUNCT
bioscience-271	106	15	spss	spss	NOUN
bioscience-271	106	16	version	version	NOUN
bioscience-271	106	17	22.0	22.0	NUM
bioscience-271	106	18	at	at	ADP
bioscience-271	106	19	a	a	DET
bioscience-271	106	20	significance	significance	NOUN
bioscience-271	106	21	level	level	NOUN
bioscience-271	106	22	of	of	ADP
bioscience-271	106	23	p	p	NOUN
bioscience-271	106	24	<	<	X
bioscience-271	106	25	0.05	0.05	NUM
bioscience-271	106	26	.	.	PUNCT
bioscience-271	107	1	in	in	ADP
bioscience-271	107	2	silico	silico	NOUN
bioscience-271	107	3	and	and	CCONJ
bioscience-271	107	4	molecular	molecular	ADJ
bioscience-271	107	5	docking	docking	NOUN
bioscience-271	107	6	of	of	ADP
bioscience-271	107	7	streptococcus	streptococcus	NOUN
bioscience-271	107	8	agalactiae	agalactiae	ADJ
bioscience-271	107	9	virulence	virulence	NOUN
bioscience-271	107	10	factors	factor	NOUN
bioscience-271	107	11	protein	protein	NOUN
bioscience-271	107	12	and	and	CCONJ
bioscience-271	107	13	ligand	ligand	NOUN
bioscience-271	107	14	modelling	modelling	NOUN
bioscience-271	107	15	for	for	ADP
bioscience-271	107	16	docking	dock	VERB
bioscience-271	107	17	studies	study	NOUN
bioscience-271	107	18	the	the	DET
bioscience-271	107	19	virulence	virulence	NOUN
bioscience-271	107	20	proteins	protein	NOUN
bioscience-271	107	21	of	of	ADP
bioscience-271	107	22	s.	s.	PROPN
bioscience-271	107	23	agalactiae	agalactiae	PROPN
bioscience-271	107	24	,	,	PUNCT
bioscience-271	107	25	such	such	ADJ
bioscience-271	107	26	as	as	ADP
bioscience-271	107	27	the	the	DET
bioscience-271	107	28	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	107	29	enzyme	enzyme	NOUN
bioscience-271	107	30	encoded	encode	VERB
bioscience-271	107	31	by	by	ADP
bioscience-271	107	32	the	the	DET
bioscience-271	107	33	iaga	iaga	NOUN
bioscience-271	107	34	gene	gene	NOUN
bioscience-271	107	35	involved	involve	VERB
bioscience-271	107	36	in	in	ADP
bioscience-271	107	37	bbb	bbb	PROPN
bioscience-271	107	38	invasion	invasion	NOUN
bioscience-271	107	39	,	,	PUNCT
bioscience-271	107	40	and	and	CCONJ
bioscience-271	107	41	an	an	DET
bioscience-271	107	42	invasin	invasin	NOUN
bioscience-271	107	43	protein	protein	NOUN
bioscience-271	107	44	,	,	PUNCT
bioscience-271	107	45	camp	camp	NOUN
bioscience-271	107	46	factor	factor	NOUN
bioscience-271	107	47	[	[	X
bioscience-271	107	48	24	24	NUM
bioscience-271	107	49	;	;	PUNCT
bioscience-271	107	50	25	25	NUM
bioscience-271	107	51	;	;	PUNCT
bioscience-271	107	52	27	27	NUM
bioscience-271	107	53	;	;	PUNCT
bioscience-271	107	54	28	28	NUM
bioscience-271	107	55	]	]	PUNCT
bioscience-271	107	56	,	,	PUNCT
bioscience-271	107	57	were	be	AUX
bioscience-271	107	58	retrieved	retrieve	VERB
bioscience-271	107	59	from	from	ADP
bioscience-271	107	60	the	the	DET
bioscience-271	107	61	ncbi	ncbi	PROPN
bioscience-271	107	62	database	database	NOUN
bioscience-271	107	63	for	for	ADP
bioscience-271	107	64	further	further	ADJ
bioscience-271	107	65	detailed	detailed	ADJ
bioscience-271	107	66	analysis	analysis	NOUN
bioscience-271	107	67	and	and	CCONJ
bioscience-271	107	68	understanding	understanding	NOUN
bioscience-271	107	69	.	.	PUNCT
bioscience-271	108	1	the	the	DET
bioscience-271	108	2	corresponding	corresponding	ADJ
bioscience-271	108	3	fasta	fasta	PROPN
bioscience-271	108	4	protein	protein	NOUN
bioscience-271	108	5	sequences	sequence	NOUN
bioscience-271	108	6	were	be	AUX
bioscience-271	108	7	subsequently	subsequently	ADV
bioscience-271	108	8	subjected	subject	VERB
bioscience-271	108	9	to	to	ADP
bioscience-271	108	10	homology	homology	NOUN
bioscience-271	108	11	modelling	modelling	NOUN
bioscience-271	108	12	using	use	VERB
bioscience-271	108	13	the	the	DET
bioscience-271	108	14	expasy	expasy	ADJ
bioscience-271	108	15	swiss	swiss	ADJ
bioscience-271	108	16	-	-	PUNCT
bioscience-271	108	17	model	model	NOUN
bioscience-271	108	18	server	server	NOUN
bioscience-271	108	19	.	.	PUNCT
bioscience-271	108	20	oxolinic	oxolinic	ADJ
bioscience-271	108	21	acid	acid	NOUN
bioscience-271	108	22	(	(	PUNCT
bioscience-271	108	23	oa	oa	NOUN
bioscience-271	108	24	)	)	PUNCT
bioscience-271	108	25	was	be	AUX
bioscience-271	108	26	considered	consider	VERB
bioscience-271	108	27	the	the	DET
bioscience-271	108	28	ligand	ligand	NOUN
bioscience-271	108	29	,	,	PUNCT
bioscience-271	108	30	and	and	CCONJ
bioscience-271	108	31	its	its	PRON
bioscience-271	108	32	3d	3d	NOUN
bioscience-271	108	33	structure	structure	NOUN
bioscience-271	108	34	was	be	AUX
bioscience-271	108	35	obtained	obtain	VERB
bioscience-271	108	36	from	from	ADP
bioscience-271	108	37	the	the	DET
bioscience-271	108	38	pubchem	pubchem	NOUN
bioscience-271	108	39	database	database	NOUN
bioscience-271	108	40	in	in	ADP
bioscience-271	108	41	.sdf	.sdf	NOUN
bioscience-271	108	42	format	format	NOUN
bioscience-271	108	43	and	and	CCONJ
bioscience-271	108	44	then	then	ADV
bioscience-271	108	45	conveniently	conveniently	ADV
bioscience-271	108	46	converted	convert	VERB
bioscience-271	108	47	to	to	ADP
bioscience-271	108	48	.pdb	.pdb	PUNCT
bioscience-271	108	49	format	format	NOUN
bioscience-271	108	50	using	use	VERB
bioscience-271	108	51	open	open	ADJ
bioscience-271	108	52	babel	babel	NOUN
bioscience-271	108	53	software	software	NOUN
bioscience-271	108	54	.	.	PUNCT
bioscience-271	109	1	molecular	molecular	ADJ
bioscience-271	109	2	docking	dock	VERB
bioscience-271	109	3	the	the	DET
bioscience-271	109	4	molecular	molecular	ADJ
bioscience-271	109	5	docking	docking	NOUN
bioscience-271	109	6	and	and	CCONJ
bioscience-271	109	7	interactions	interaction	NOUN
bioscience-271	109	8	between	between	ADP
bioscience-271	109	9	oa	oa	PROPN
bioscience-271	109	10	and	and	CCONJ
bioscience-271	109	11	the	the	DET
bioscience-271	109	12	target	target	NOUN
bioscience-271	109	13	virulence	virulence	NOUN
bioscience-271	109	14	proteins	protein	NOUN
bioscience-271	109	15	of	of	ADP
bioscience-271	109	16	s.	s.	PROPN
bioscience-271	109	17	agalactiae	agalactiae	PROPN
bioscience-271	109	18	were	be	AUX
bioscience-271	109	19	analysed	analyse	VERB
bioscience-271	109	20	using	use	VERB
bioscience-271	109	21	mgl	mgl	ADJ
bioscience-271	109	22	tools	tool	NOUN
bioscience-271	109	23	and	and	CCONJ
bioscience-271	109	24	autodock	autodock	NOUN
bioscience-271	109	25	tools	tool	NOUN
bioscience-271	109	26	1.5.7	1.5.7	PROPN
bioscience-271	110	1	[	[	X
bioscience-271	110	2	35	35	NUM
bioscience-271	110	3	]	]	PUNCT
bioscience-271	110	4	,	,	PUNCT
bioscience-271	110	5	employing	employ	VERB
bioscience-271	110	6	a	a	DET
bioscience-271	110	7	grid	grid	NOUN
bioscience-271	110	8	box	box	NOUN
bioscience-271	110	9	size	size	NOUN
bioscience-271	110	10	of	of	ADP
bioscience-271	110	11	126	126	NUM
bioscience-271	110	12	å	å	NOUN
bioscience-271	110	13	in	in	ADP
bioscience-271	110	14	the	the	DET
bioscience-271	110	15	x	x	PROPN
bioscience-271	110	16	,	,	PUNCT
bioscience-271	110	17	y	y	PROPN
bioscience-271	110	18	,	,	PUNCT
bioscience-271	110	19	and	and	CCONJ
bioscience-271	110	20	z	z	NOUN
bioscience-271	110	21	dimensions	dimension	NOUN
bioscience-271	110	22	,	,	PUNCT
bioscience-271	110	23	and	and	CCONJ
bioscience-271	110	24	the	the	DET
bioscience-271	110	25	lamarckian	lamarckian	ADJ
bioscience-271	110	26	genetic	genetic	ADJ
bioscience-271	110	27	algorithm	algorithm	NOUN
bioscience-271	110	28	for	for	ADP
bioscience-271	110	29	docking	dock	VERB
bioscience-271	110	30	simulations	simulation	NOUN
bioscience-271	110	31	.	.	PUNCT
bioscience-271	111	1	the	the	DET
bioscience-271	111	2	docking	docking	NOUN
bioscience-271	111	3	results	result	NOUN
bioscience-271	111	4	and	and	CCONJ
bioscience-271	111	5	molecular	molecular	ADJ
bioscience-271	111	6	interactions	interaction	NOUN
bioscience-271	111	7	were	be	AUX
bioscience-271	111	8	visualised	visualise	VERB
bioscience-271	111	9	using	use	VERB
bioscience-271	111	10	pymol	pymol	PROPN
bioscience-271	111	11	edu	edu	PROPN
bioscience-271	111	12	version	version	PROPN
bioscience-271	111	13	2.5	2.5	NUM
bioscience-271	111	14	.	.	PUNCT
bioscience-271	112	1	the	the	DET
bioscience-271	112	2	docking	docking	NOUN
bioscience-271	112	3	score	score	NOUN
bioscience-271	112	4	,	,	PUNCT
bioscience-271	112	5	representing	represent	VERB
bioscience-271	112	6	the	the	DET
bioscience-271	112	7	interaction	interaction	NOUN
bioscience-271	112	8	energy	energy	NOUN
bioscience-271	112	9	with	with	ADP
bioscience-271	112	10	appropriate	appropriate	ADJ
bioscience-271	112	11	scaling	scaling	NOUN
bioscience-271	112	12	factors	factor	NOUN
bioscience-271	112	13	,	,	PUNCT
bioscience-271	112	14	was	be	AUX
bioscience-271	112	15	used	use	VERB
bioscience-271	112	16	to	to	PART
bioscience-271	112	17	assess	assess	VERB
bioscience-271	112	18	the	the	DET
bioscience-271	112	19	binding	bind	VERB
bioscience-271	112	20	affinity	affinity	NOUN
bioscience-271	112	21	of	of	ADP
bioscience-271	112	22	the	the	DET
bioscience-271	112	23	ligand	ligand	NOUN
bioscience-271	112	24	.	.	PUNCT
bioscience-271	113	1	furthermore	furthermore	ADV
bioscience-271	113	2	,	,	PUNCT
bioscience-271	113	3	specific	specific	ADJ
bioscience-271	113	4	amino	amino	NOUN
bioscience-271	113	5	acid	acid	NOUN
bioscience-271	113	6	interactions	interaction	NOUN
bioscience-271	113	7	between	between	ADP
bioscience-271	113	8	the	the	DET
bioscience-271	113	9	ligand	ligand	ADJ
bioscience-271	113	10	and	and	CCONJ
bioscience-271	113	11	target	target	NOUN
bioscience-271	113	12	proteins	protein	NOUN
bioscience-271	113	13	were	be	AUX
bioscience-271	113	14	computed	compute	VERB
bioscience-271	113	15	and	and	CCONJ
bioscience-271	113	16	outlined	outline	VERB
bioscience-271	113	17	.	.	PUNCT
bioscience-271	114	1	lower	low	ADJ
bioscience-271	114	2	binding	binding	ADJ
bioscience-271	114	3	free	free	ADJ
bioscience-271	114	4	energy	energy	NOUN
bioscience-271	114	5	may	may	AUX
bioscience-271	114	6	indicate	indicate	VERB
bioscience-271	114	7	stronger	strong	ADJ
bioscience-271	114	8	ligand	ligand	NOUN
bioscience-271	114	9	-	-	PUNCT
bioscience-271	114	10	protein	protein	NOUN
bioscience-271	114	11	interaction	interaction	NOUN
bioscience-271	114	12	,	,	PUNCT
bioscience-271	114	13	while	while	SCONJ
bioscience-271	114	14	hydrogen	hydrogen	NOUN
bioscience-271	114	15	bond	bond	NOUN
bioscience-271	114	16	strength	strength	NOUN
bioscience-271	114	17	may	may	AUX
bioscience-271	114	18	categorise	categorise	VERB
bioscience-271	114	19	donoracceptor	donoracceptor	NOUN
bioscience-271	114	20	distances	distance	NOUN
bioscience-271	114	21	as	as	ADP
bioscience-271	114	22	strong	strong	ADJ
bioscience-271	114	23	(	(	PUNCT
bioscience-271	114	24	2.2–2.5	2.2–2.5	NUM
bioscience-271	114	25	å	å	ADJ
bioscience-271	114	26	;	;	PUNCT
bioscience-271	114	27	mostly	mostly	ADV
bioscience-271	114	28	covalent	covalent	NOUN
bioscience-271	114	29	)	)	PUNCT
bioscience-271	114	30	,	,	PUNCT
bioscience-271	114	31	moderate	moderate	ADJ
bioscience-271	114	32	(	(	PUNCT
bioscience-271	114	33	2.5–3.2	2.5–3.2	NUM
bioscience-271	114	34	å	å	NOUN
bioscience-271	114	35	;	;	PUNCT
bioscience-271	114	36	mostly	mostly	ADV
bioscience-271	114	37	electrostatic	electrostatic	ADJ
bioscience-271	114	38	)	)	PUNCT
bioscience-271	114	39	,	,	PUNCT
bioscience-271	114	40	and	and	CCONJ
bioscience-271	114	41	weak	weak	ADJ
bioscience-271	114	42	(	(	PUNCT
bioscience-271	114	43	3.2–4.0	3.2–4.0	NUM
bioscience-271	114	44	å	å	NOUN
bioscience-271	114	45	;	;	PUNCT
bioscience-271	114	46	electrostatic	electrostatic	ADJ
bioscience-271	114	47	)	)	PUNCT
bioscience-271	114	48	,	,	PUNCT
bioscience-271	114	49	as	as	ADP
bioscience-271	114	50	per	per	ADP
bioscience-271	114	51	jeffrey	jeffrey	NOUN
bioscience-271	115	1	[	[	X
bioscience-271	115	2	36	36	NUM
bioscience-271	115	3	]	]	PUNCT
bioscience-271	115	4	.	.	PUNCT
bioscience-271	116	1	results	result	VERB
bioscience-271	116	2	brain	brain	NOUN
bioscience-271	116	3	histopathology	histopathology	NOUN
bioscience-271	116	4	and	and	CCONJ
bioscience-271	116	5	evaluation	evaluation	NOUN
bioscience-271	116	6	of	of	ADP
bioscience-271	116	7	pathological	pathological	ADJ
bioscience-271	116	8	anomalies	anomaly	NOUN
bioscience-271	116	9	the	the	DET
bioscience-271	116	10	ld50	ld50	PROPN
bioscience-271	116	11	of	of	ADP
bioscience-271	116	12	s.	s.	PROPN
bioscience-271	116	13	agalactiae	agalactiae	PROPN
bioscience-271	116	14	and	and	CCONJ
bioscience-271	116	15	the	the	DET
bioscience-271	116	16	mic	mic	NOUN
bioscience-271	116	17	of	of	ADP
bioscience-271	116	18	oxolinic	oxolinic	ADJ
bioscience-271	116	19	acid	acid	NOUN
bioscience-271	116	20	(	(	PUNCT
bioscience-271	116	21	oa	oa	NOUN
bioscience-271	116	22	)	)	PUNCT
bioscience-271	116	23	were	be	AUX
bioscience-271	116	24	1.26	1.26	NUM
bioscience-271	116	25	×	×	NOUN
bioscience-271	116	26	108	108	NUM
bioscience-271	116	27	cells	cell	NOUN
bioscience-271	116	28	/	/	SYM
bioscience-271	116	29	fish	fish	NOUN
bioscience-271	116	30	and	and	CCONJ
bioscience-271	116	31	12.50	12.50	NUM
bioscience-271	116	32	µg	µg	NOUN
bioscience-271	116	33	/	/	SYM
bioscience-271	116	34	ml	ml	NOUN
bioscience-271	116	35	,	,	PUNCT
bioscience-271	116	36	respectively	respectively	ADV
bioscience-271	116	37	.	.	PUNCT
bioscience-271	117	1	in	in	ADP
bioscience-271	117	2	the	the	DET
bioscience-271	117	3	forebrain	forebrain	NOUN
bioscience-271	117	4	of	of	ADP
bioscience-271	117	5	the	the	DET
bioscience-271	117	6	control	control	NOUN
bioscience-271	117	7	fish	fish	NOUN
bioscience-271	117	8	,	,	PUNCT
bioscience-271	117	9	the	the	DET
bioscience-271	117	10	tissue	tissue	NOUN
bioscience-271	117	11	structure	structure	NOUN
bioscience-271	117	12	was	be	AUX
bioscience-271	117	13	normal	normal	ADJ
bioscience-271	117	14	,	,	PUNCT
bioscience-271	117	15	with	with	ADP
bioscience-271	117	16	a	a	DET
bioscience-271	117	17	well	well	ADV
bioscience-271	117	18	-	-	PUNCT
bioscience-271	117	19	organized	organize	VERB
bioscience-271	117	20	epithelial	epithelial	ADJ
bioscience-271	117	21	layer	layer	NOUN
bioscience-271	117	22	,	,	PUNCT
bioscience-271	117	23	the	the	DET
bioscience-271	117	24	meninx	meninx	PROPN
bioscience-271	117	25	primitiva	primitiva	PROPN
bioscience-271	117	26	,	,	PUNCT
bioscience-271	117	27	and	and	CCONJ
bioscience-271	117	28	mononuclear	mononuclear	ADJ
bioscience-271	117	29	cells	cell	NOUN
bioscience-271	117	30	present	present	ADJ
bioscience-271	117	31	in	in	ADP
bioscience-271	117	32	the	the	DET
bioscience-271	117	33	brain	brain	NOUN
bioscience-271	117	34	parenchyma	parenchyma	NOUN
bioscience-271	117	35	(	(	PUNCT
bioscience-271	117	36	figure	figure	NOUN
bioscience-271	117	37	1	1	NUM
bioscience-271	117	38	a	a	NOUN
bioscience-271	117	39	)	)	PUNCT
bioscience-271	117	40	.	.	PUNCT
bioscience-271	118	1	the	the	DET
bioscience-271	118	2	histopathological	histopathological	ADJ
bioscience-271	118	3	analyses	analysis	NOUN
bioscience-271	118	4	of	of	ADP
bioscience-271	118	5	oa	oa	ADV
bioscience-271	118	6	-	-	PUNCT
bioscience-271	118	7	treated	treat	VERB
bioscience-271	118	8	and	and	CCONJ
bioscience-271	118	9	untreated	untreated	ADJ
bioscience-271	118	10	s.	s.	PROPN
bioscience-271	118	11	agalactiae	agalactiae	PROPN
bioscience-271	118	12	challenged	challenge	VERB
bioscience-271	118	13	o.	o.	PROPN
bioscience-271	118	14	niloticus	niloticus	PROPN
bioscience-271	118	15	revealed	reveal	VERB
bioscience-271	118	16	three	three	NUM
bioscience-271	118	17	types	type	NOUN
bioscience-271	118	18	of	of	ADP
bioscience-271	118	19	reaction	reaction	NOUN
bioscience-271	118	20	patterns	pattern	NOUN
bioscience-271	118	21	:	:	PUNCT
bioscience-271	118	22	progressive	progressive	ADJ
bioscience-271	118	23	,	,	PUNCT
bioscience-271	118	24	regressive	regressive	ADJ
bioscience-271	118	25	,	,	PUNCT
bioscience-271	118	26	and	and	CCONJ
bioscience-271	118	27	inflammatory	inflammatory	ADJ
bioscience-271	118	28	(	(	PUNCT
bioscience-271	118	29	figure	figure	NOUN
bioscience-271	118	30	1	1	NUM
bioscience-271	118	31	b	b	X
bioscience-271	118	32	–	–	PUNCT
bioscience-271	118	33	i	i	NOUN
bioscience-271	118	34	;	;	PUNCT
bioscience-271	118	35	table	table	NOUN
bioscience-271	118	36	1	1	NUM
bioscience-271	118	37	)	)	PUNCT
bioscience-271	118	38	.	.	PUNCT
bioscience-271	119	1	the	the	DET
bioscience-271	119	2	identified	identify	VERB
bioscience-271	119	3	progressive	progressive	ADJ
bioscience-271	119	4	change	change	NOUN
bioscience-271	119	5	was	be	AUX
bioscience-271	119	6	thickening	thicken	VERB
bioscience-271	119	7	of	of	ADP
bioscience-271	119	8	the	the	DET
bioscience-271	119	9	meninx	meninx	PROPN
bioscience-271	119	10	primitiva	primitiva	PROPN
bioscience-271	119	11	,	,	PUNCT
bioscience-271	119	12	while	while	SCONJ
bioscience-271	119	13	regressive	regressive	ADJ
bioscience-271	119	14	changes	change	NOUN
bioscience-271	119	15	included	include	VERB
bioscience-271	119	16	superficial	superficial	ADJ
bioscience-271	119	17	layer	layer	NOUN
bioscience-271	119	18	lifting	lifting	NOUN
bioscience-271	119	19	,	,	PUNCT
bioscience-271	119	20	localized	localize	VERB
bioscience-271	119	21	spongiform	spongiform	NOUN
bioscience-271	119	22	encephalopathy	encephalopathy	NOUN
bioscience-271	119	23	,	,	PUNCT
bioscience-271	119	24	vacuolation	vacuolation	NOUN
bioscience-271	119	25	,	,	PUNCT
bioscience-271	119	26	and	and	CCONJ
bioscience-271	119	27	degeneration	degeneration	NOUN
bioscience-271	119	28	of	of	ADP
bioscience-271	119	29	the	the	DET
bioscience-271	119	30	meninx	meninx	PROPN
bioscience-271	119	31	primitiva	primitiva	NOUN
bioscience-271	119	32	and	and	CCONJ
bioscience-271	119	33	brain	brain	NOUN
bioscience-271	119	34	parenchyma	parenchyma	NOUN
bioscience-271	119	35	.	.	PUNCT
bioscience-271	120	1	inflammatory	inflammatory	ADJ
bioscience-271	120	2	changes	change	NOUN
bioscience-271	120	3	were	be	AUX
bioscience-271	120	4	characterized	characterize	VERB
bioscience-271	120	5	by	by	ADP
bioscience-271	120	6	meningitis	meningitis	ADJ
bioscience-271	120	7	and	and	CCONJ
bioscience-271	120	8	mononuclear	mononuclear	ADJ
bioscience-271	120	9	cell	cell	NOUN
bioscience-271	120	10	infiltration	infiltration	NOUN
bioscience-271	120	11	.	.	PUNCT
bioscience-271	121	1	on	on	ADP
bioscience-271	121	2	dpi	dpi	PROPN
bioscience-271	121	3	1	1	NUM
bioscience-271	121	4	,	,	PUNCT
bioscience-271	121	5	both	both	DET
bioscience-271	121	6	groups	group	NOUN
bioscience-271	121	7	displayed	display	VERB
bioscience-271	121	8	mild	mild	ADJ
bioscience-271	121	9	progressive	progressive	ADJ
bioscience-271	121	10	,	,	PUNCT
bioscience-271	121	11	regressive	regressive	ADJ
bioscience-271	121	12	,	,	PUNCT
bioscience-271	121	13	and	and	CCONJ
bioscience-271	121	14	inflammatory	inflammatory	ADJ
bioscience-271	121	15	changes	change	NOUN
bioscience-271	121	16	,	,	PUNCT
bioscience-271	121	17	including	include	VERB
bioscience-271	121	18	meninx	meninx	PROPN
bioscience-271	121	19	primitiva	primitiva	NOUN
bioscience-271	121	20	thickening	thickening	NOUN
bioscience-271	121	21	with	with	ADP
bioscience-271	121	22	high	high	ADJ
bioscience-271	121	23	ri	ri	PROPN
bioscience-271	121	24	values	value	NOUN
bioscience-271	121	25	.	.	PUNCT
bioscience-271	122	1	the	the	DET
bioscience-271	122	2	damage	damage	NOUN
bioscience-271	122	3	,	,	PUNCT
bioscience-271	122	4	particularly	particularly	ADV
bioscience-271	122	5	regressive	regressive	ADJ
bioscience-271	122	6	and	and	CCONJ
bioscience-271	122	7	inflammatory	inflammatory	ADJ
bioscience-271	122	8	changes	change	NOUN
bioscience-271	122	9	,	,	PUNCT
bioscience-271	122	10	intensified	intensify	VERB
bioscience-271	122	11	on	on	ADP
bioscience-271	122	12	dpi	dpi	PROPN
bioscience-271	122	13	7	7	NUM
bioscience-271	122	14	.	.	PUNCT
bioscience-271	123	1	the	the	DET
bioscience-271	123	2	oa	oa	ADV
bioscience-271	123	3	-	-	PUNCT
bioscience-271	123	4	treated	treat	VERB
bioscience-271	123	5	group	group	NOUN
bioscience-271	123	6	showed	show	VERB
bioscience-271	123	7	reduced	reduce	VERB
bioscience-271	123	8	regressive	regressive	ADJ
bioscience-271	123	9	changes	change	NOUN
bioscience-271	123	10	and	and	CCONJ
bioscience-271	123	11	evidence	evidence	NOUN
bioscience-271	123	12	of	of	ADP
bioscience-271	123	13	healing	healing	NOUN
bioscience-271	123	14	in	in	ADP
bioscience-271	123	15	the	the	DET
bioscience-271	123	16	brain	brain	NOUN
bioscience-271	123	17	parenchyma	parenchyma	NOUN
bioscience-271	123	18	,	,	PUNCT
bioscience-271	123	19	whereas	whereas	SCONJ
bioscience-271	123	20	the	the	DET
bioscience-271	123	21	untreated	untreated	ADJ
bioscience-271	123	22	group	group	NOUN
bioscience-271	123	23	experienced	experience	VERB
bioscience-271	123	24	significant	significant	ADJ
bioscience-271	123	25	damage	damage	NOUN
bioscience-271	123	26	on	on	ADP
bioscience-271	123	27	dpi	dpi	PROPN
bioscience-271	123	28	14	14	NUM
bioscience-271	123	29	.	.	PUNCT
bioscience-271	124	1	by	by	ADP
bioscience-271	124	2	dpi	dpi	PROPN
bioscience-271	124	3	21	21	NUM
bioscience-271	124	4	,	,	PUNCT
bioscience-271	124	5	the	the	DET
bioscience-271	124	6	oa	oa	ADV
bioscience-271	124	7	-	-	PUNCT
bioscience-271	124	8	treated	treat	VERB
bioscience-271	124	9	group	group	NOUN
bioscience-271	124	10	was	be	AUX
bioscience-271	124	11	nearly	nearly	ADV
bioscience-271	124	12	healed	heal	VERB
bioscience-271	124	13	except	except	SCONJ
bioscience-271	124	14	for	for	ADP
bioscience-271	124	15	mild	mild	ADJ
bioscience-271	124	16	meningitis	meningiti	NOUN
bioscience-271	124	17	,	,	PUNCT
bioscience-271	124	18	while	while	SCONJ
bioscience-271	124	19	the	the	DET
bioscience-271	124	20	untreated	untreated	ADJ
bioscience-271	124	21	group	group	NOUN
bioscience-271	124	22	continued	continue	VERB
bioscience-271	124	23	to	to	PART
bioscience-271	124	24	exhibit	exhibit	VERB
bioscience-271	124	25	moderate	moderate	ADJ
bioscience-271	124	26	brain	brain	NOUN
bioscience-271	124	27	damage	damage	NOUN
bioscience-271	124	28	.	.	PUNCT
bioscience-271	125	1	in	in	ADP
bioscience-271	125	2	the	the	DET
bioscience-271	125	3	midbrain	midbrain	NOUN
bioscience-271	125	4	,	,	PUNCT
bioscience-271	125	5	the	the	DET
bioscience-271	125	6	normal	normal	ADJ
bioscience-271	125	7	structure	structure	NOUN
bioscience-271	125	8	consisted	consist	VERB
bioscience-271	125	9	of	of	ADP
bioscience-271	125	10	an	an	DET
bioscience-271	125	11	outer	outer	ADJ
bioscience-271	125	12	meninx	meninx	NOUN
bioscience-271	125	13	primitiva	primitiva	NOUN
bioscience-271	125	14	and	and	CCONJ
bioscience-271	125	15	underlying	underlying	ADJ
bioscience-271	125	16	connective	connective	ADJ
bioscience-271	125	17	tissue	tissue	NOUN
bioscience-271	125	18	above	above	ADP
bioscience-271	125	19	the	the	DET
bioscience-271	125	20	optic	optic	ADJ
bioscience-271	125	21	tectum	tectum	NOUN
bioscience-271	125	22	(	(	PUNCT
bioscience-271	125	23	figure	figure	NOUN
bioscience-271	125	24	2	2	NUM
bioscience-271	125	25	a	a	NOUN
bioscience-271	125	26	)	)	PUNCT
bioscience-271	125	27	.	.	PUNCT
bioscience-271	126	1	the	the	DET
bioscience-271	126	2	histopathological	histopathological	ADJ
bioscience-271	126	3	changes	change	NOUN
bioscience-271	126	4	included	include	VERB
bioscience-271	126	5	circulatory	circulatory	ADJ
bioscience-271	126	6	alterations	alteration	NOUN
bioscience-271	126	7	such	such	ADJ
bioscience-271	126	8	as	as	ADP
bioscience-271	126	9	edematous	edematous	ADJ
bioscience-271	126	10	optic	optic	ADJ
bioscience-271	126	11	tectum	tectum	NOUN
bioscience-271	126	12	,	,	PUNCT
bioscience-271	126	13	regressive	regressive	ADJ
bioscience-271	126	14	changes	change	NOUN
bioscience-271	126	15	like	like	ADP
bioscience-271	126	16	superficial	superficial	ADJ
bioscience-271	126	17	layer	layer	NOUN
bioscience-271	126	18	lifting	lifting	NOUN
bioscience-271	126	19	,	,	PUNCT
bioscience-271	126	20	loosening	loosening	NOUN
bioscience-271	126	21	of	of	ADP
bioscience-271	126	22	connective	connective	ADJ
bioscience-271	126	23	tissue	tissue	NOUN
bioscience-271	126	24	,	,	PUNCT
bioscience-271	126	25	and	and	CCONJ
bioscience-271	126	26	vacuolation	vacuolation	NOUN
bioscience-271	126	27	,	,	PUNCT
bioscience-271	126	28	as	as	ADV
bioscience-271	126	29	well	well	ADV
bioscience-271	126	30	as	as	ADP
bioscience-271	126	31	inflammatory	inflammatory	ADJ
bioscience-271	126	32	changes	change	NOUN
bioscience-271	126	33	such	such	ADJ
bioscience-271	126	34	as	as	ADP
bioscience-271	126	35	mononuclear	mononuclear	ADJ
bioscience-271	126	36	cell	cell	NOUN
bioscience-271	126	37	infiltration	infiltration	NOUN
bioscience-271	126	38	(	(	PUNCT
bioscience-271	126	39	figure	figure	NOUN
bioscience-271	126	40	2	2	NUM
bioscience-271	126	41	b	b	NOUN
bioscience-271	126	42	–	–	PUNCT
bioscience-271	126	43	i	i	NOUN
bioscience-271	126	44	;	;	PUNCT
bioscience-271	126	45	table	table	NOUN
bioscience-271	126	46	1	1	NUM
bioscience-271	126	47	)	)	PUNCT
bioscience-271	126	48	.	.	PUNCT
bioscience-271	127	1	on	on	ADP
bioscience-271	127	2	dpi	dpi	PROPN
bioscience-271	127	3	1	1	NUM
bioscience-271	127	4	,	,	PUNCT
bioscience-271	127	5	both	both	DET
bioscience-271	127	6	groups	group	NOUN
bioscience-271	127	7	exhibited	exhibit	VERB
bioscience-271	127	8	mild	mild	ADJ
bioscience-271	127	9	circulatory	circulatory	ADJ
bioscience-271	127	10	,	,	PUNCT
bioscience-271	127	11	inflammatory	inflammatory	ADJ
bioscience-271	127	12	,	,	PUNCT
bioscience-271	127	13	and	and	CCONJ
bioscience-271	127	14	regressive	regressive	ADJ
bioscience-271	127	15	changes	change	NOUN
bioscience-271	127	16	.	.	PUNCT
bioscience-271	128	1	on	on	ADP
bioscience-271	128	2	dpi	dpi	PROPN
bioscience-271	128	3	7	7	NUM
bioscience-271	128	4	,	,	PUNCT
bioscience-271	128	5	circulatory	circulatory	ADJ
bioscience-271	128	6	damage	damage	NOUN
bioscience-271	128	7	peaked	peak	VERB
bioscience-271	128	8	in	in	ADP
bioscience-271	128	9	the	the	DET
bioscience-271	128	10	oatreated	oatreated	ADJ
bioscience-271	128	11	group	group	NOUN
bioscience-271	128	12	,	,	PUNCT
bioscience-271	128	13	while	while	SCONJ
bioscience-271	128	14	regressive	regressive	ADJ
bioscience-271	128	15	changes	change	NOUN
bioscience-271	128	16	worsened	worsen	VERB
bioscience-271	128	17	in	in	ADP
bioscience-271	128	18	the	the	DET
bioscience-271	128	19	untreated	untreated	ADJ
bioscience-271	128	20	group	group	NOUN
bioscience-271	128	21	.	.	PUNCT
bioscience-271	129	1	a	a	DET
bioscience-271	129	2	gradual	gradual	ADJ
bioscience-271	129	3	reduction	reduction	NOUN
bioscience-271	129	4	in	in	ADP
bioscience-271	129	5	damage	damage	NOUN
bioscience-271	129	6	over	over	ADP
bioscience-271	129	7	time	time	NOUN
bioscience-271	129	8	was	be	AUX
bioscience-271	129	9	noted	note	VERB
bioscience-271	129	10	in	in	ADP
bioscience-271	129	11	the	the	DET
bioscience-271	129	12	highlights	highlight	NOUN
bioscience-271	129	13	in	in	ADP
bioscience-271	129	14	bioscience	bioscience	NOUN
bioscience-271	129	15	page	page	NOUN
bioscience-271	129	16	4	4	NUM
bioscience-271	129	17	of	of	ADP
bioscience-271	129	18	10	10	NUM
bioscience-271	129	19	october	october	PROPN
bioscience-271	129	20	2025|volume	2025|volume	NUM
bioscience-271	129	21	8	8	NUM
bioscience-271	129	22	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	129	23	sinha	sinha	PROPN
bioscience-271	129	24	p	p	PROPN
bioscience-271	129	25	et	et	PROPN
bioscience-271	129	26	al	al	PROPN
bioscience-271	129	27	.	.	PROPN
bioscience-271	129	28	,	,	PUNCT
bioscience-271	129	29	2025	2025	NUM
bioscience-271	129	30	effect	effect	NOUN
bioscience-271	129	31	of	of	ADP
bioscience-271	129	32	oxolinic	oxolinic	ADJ
bioscience-271	129	33	acid	acid	NOUN
bioscience-271	129	34	therapy	therapy	NOUN
bioscience-271	129	35	table	table	NOUN
bioscience-271	129	36	1	1	NUM
bioscience-271	129	37	.	.	PUNCT
bioscience-271	130	1	reaction	reaction	NOUN
bioscience-271	130	2	indices	index	NOUN
bioscience-271	130	3	*	*	VERB
bioscience-271	130	4	based	base	VERB
bioscience-271	130	5	on	on	ADP
bioscience-271	130	6	the	the	DET
bioscience-271	130	7	major	major	ADJ
bioscience-271	130	8	histopathological	histopathological	ADJ
bioscience-271	130	9	changes	change	NOUN
bioscience-271	130	10	in	in	ADP
bioscience-271	130	11	the	the	DET
bioscience-271	130	12	brain	brain	NOUN
bioscience-271	130	13	of	of	ADP
bioscience-271	130	14	streptococcus	streptococcus	NOUN
bioscience-271	130	15	agalactiae	agalactiae	PROPN
bioscience-271	130	16	lcr1	lcr1	PROPN
bioscience-271	130	17	challenged	challenge	VERB
bioscience-271	130	18	and	and	CCONJ
bioscience-271	130	19	oxolinic	oxolinic	ADJ
bioscience-271	130	20	acid	acid	NOUN
bioscience-271	130	21	(	(	PUNCT
bioscience-271	130	22	oa)-fed	oa)-fed	PROPN
bioscience-271	130	23	oreochromis	oreochromis	PROPN
bioscience-271	130	24	niloticus	niloticus	PROPN
bioscience-271	130	25	juveniles	juvenile	NOUN
bioscience-271	130	26	.	.	PUNCT
bioscience-271	131	1	reaction	reaction	NOUN
bioscience-271	131	2	pattern	pattern	NOUN
bioscience-271	131	3	histopathological	histopathological	ADJ
bioscience-271	131	4	changes	change	NOUN
bioscience-271	131	5	if	if	SCONJ
bioscience-271	131	6	dpi	dpi	NOUN
bioscience-271	131	7	1	1	NUM
bioscience-271	131	8	dpi	dpi	NOUN
bioscience-271	131	9	7	7	NUM
bioscience-271	131	10	dpi	dpi	NOUN
bioscience-271	131	11	14	14	NUM
bioscience-271	131	12	dpi	dpi	NOUN
bioscience-271	131	13	21	21	NUM
bioscience-271	131	14	oa	oa	PRON
bioscience-271	131	15	treated	treat	VERB
bioscience-271	131	16	untreated	untreated	ADJ
bioscience-271	131	17	oa	oa	PRON
bioscience-271	131	18	treated	treat	VERB
bioscience-271	131	19	untreated	untreated	ADJ
bioscience-271	131	20	oa	oa	PRON
bioscience-271	131	21	treated	treat	VERB
bioscience-271	131	22	untreated	untreated	ADJ
bioscience-271	131	23	oa	oa	PRON
bioscience-271	131	24	treated	treat	VERB
bioscience-271	131	25	untreated	untreated	ADJ
bioscience-271	131	26	forebrain	forebrain	NOUN
bioscience-271	131	27	progressive	progressive	ADJ
bioscience-271	131	28	thickening	thickening	NOUN
bioscience-271	131	29	of	of	ADP
bioscience-271	131	30	mp	mp	PROPN
bioscience-271	131	31	1	1	NUM
bioscience-271	131	32	0.80±0.171ab	0.80±0.171ab	NOUN
bioscience-271	131	33	1.02±0.551ab	1.02±0.551ab	NUM
bioscience-271	132	1	1.06±0.271a	1.06±0.271a	NUM
bioscience-271	133	1	1.12±0.211a	1.12±0.211a	NUM
bioscience-271	133	2	0.57±0.251b	0.57±0.251b	NOUN
bioscience-271	134	1	0.72±0.301	0.72±0.301	PUNCT
bioscience-271	134	2	a	a	DET
bioscience-271	134	3	b	b	PROPN
bioscience-271	135	1	0.27±0.121c	0.27±0.121c	NOUN
bioscience-271	135	2	0.57±0.102	0.57±0.102	PUNCT
bioscience-271	136	1	b	b	NOUN
bioscience-271	136	2	regressive	regressive	ADJ
bioscience-271	136	3	lifting	lifting	NOUN
bioscience-271	136	4	of	of	ADP
bioscience-271	136	5	sl	sl	INTJ
bioscience-271	136	6	1	1	NUM
bioscience-271	136	7	0.52±0.451ab	0.52±0.451ab	NOUN
bioscience-271	136	8	1.07±0.531a	1.07±0.531a	NUM
bioscience-271	136	9	0.62±0.241a	0.62±0.241a	NOUN
bioscience-271	137	1	0.98±0.371a	0.98±0.371a	VERB
bioscience-271	137	2	0.25±0.121ab	0.25±0.121ab	NUM
bioscience-271	138	1	1.05±0.432	1.05±0.432	NUM
bioscience-271	139	1	a	a	DET
bioscience-271	139	2	0.23±0.051b	0.23±0.051b	ADJ
bioscience-271	139	3	0.47±0.192	0.47±0.192	PUNCT
bioscience-271	140	1	b	b	NOUN
bioscience-271	140	2	lse	lse	NOUN
bioscience-271	140	3	2	2	NUM
bioscience-271	140	4	2.10±1.181ab	2.10±1.181ab	NUM
bioscience-271	140	5	1.67±1.541a	1.67±1.541a	NOUN
bioscience-271	140	6	2.60±0.491a	2.60±0.491a	PUNCT
bioscience-271	141	1	3.80±1.211	3.80±1.211	PROPN
bioscience-271	141	2	b	b	NOUN
bioscience-271	141	3	1.07±0.211bc	1.07±0.211bc	NUM
bioscience-271	141	4	1.63±0.392	1.63±0.392	NOUN
bioscience-271	141	5	a	a	DET
bioscience-271	141	6	0.83±0.461c	0.83±0.461c	NUM
bioscience-271	141	7	1.27±0.391a	1.27±0.391a	ADJ
bioscience-271	141	8	vacuolation	vacuolation	NOUN
bioscience-271	141	9	2	2	NUM
bioscience-271	141	10	1.93±0.641ab	1.93±0.641ab	NUM
bioscience-271	141	11	1.13±0.631a	1.13±0.631a	NUM
bioscience-271	141	12	1.93±0.651a	1.93±0.651a	NOUN
bioscience-271	142	1	3.47±1.042	3.47±1.042	PROPN
bioscience-271	142	2	b	b	PROPN
bioscience-271	142	3	1.03±0.591ab	1.03±0.591ab	NUM
bioscience-271	142	4	1.73±0.621	1.73±0.621	PROPN
bioscience-271	142	5	a	a	PRON
bioscience-271	142	6	0.67±0.331b	0.67±0.331b	ADJ
bioscience-271	142	7	1.33±0.552a	1.33±0.552a	PROPN
bioscience-271	142	8	damaged	damage	VERB
bioscience-271	142	9	mp	mp	PROPN
bioscience-271	142	10	3	3	NUM
bioscience-271	142	11	3.05±1.261ab	3.05±1.261ab	NUM
bioscience-271	142	12	2.95±1.221a	2.95±1.221a	PROPN
bioscience-271	142	13	b	b	NOUN
bioscience-271	142	14	3.05±0.481a	3.05±0.481a	NUM
bioscience-271	142	15	5.55±2.541a	5.55±2.541a	NOUN
bioscience-271	142	16	1.70±0.921ab	1.70±0.921ab	NOUN
bioscience-271	143	1	3.55±1.721	3.55±1.721	PROPN
bioscience-271	143	2	a	a	DET
bioscience-271	143	3	b	b	PROPN
bioscience-271	143	4	1.00±0.491b	1.00±0.491b	PROPN
bioscience-271	143	5	2.20±0.622	2.20±0.622	NOUN
bioscience-271	143	6	b	b	NOUN
bioscience-271	143	7	degeneration	degeneration	NOUN
bioscience-271	143	8	of	of	ADP
bioscience-271	143	9	bp	bp	PROPN
bioscience-271	143	10	3	3	NUM
bioscience-271	143	11	3.00±1.001ab	3.00±1.001ab	NUM
bioscience-271	143	12	1.90±1.381a	1.90±1.381a	PROPN
bioscience-271	144	1	3.00±0.801b	3.00±0.801b	PROPN
bioscience-271	145	1	5.70±1.612	5.70±1.612	PROPN
bioscience-271	145	2	b	b	PROPN
bioscience-271	145	3	1.05±1.321a	1.05±1.321a	ADJ
bioscience-271	145	4	3.15±0.732c	3.15±0.732c	NUM
bioscience-271	145	5	0.75±0.371a	0.75±0.371a	SYM
bioscience-271	145	6	1.90±0.822a	1.90±0.822a	NUM
bioscience-271	145	7	inflammatory	inflammatory	ADJ
bioscience-271	145	8	meningitis	meningitis	NOUN
bioscience-271	145	9	2	2	NUM
bioscience-271	145	10	3.57±0.411a	3.57±0.411a	NUM
bioscience-271	145	11	1.70±1.271a	1.70±1.271a	PROPN
bioscience-271	145	12	3.57±1.241b	3.57±1.241b	NOUN
bioscience-271	146	1	3.90±1.051	3.90±1.051	NUM
bioscience-271	146	2	b	b	NOUN
bioscience-271	146	3	1.13±0.391a	1.13±0.391a	PRON
bioscience-271	147	1	2.03±0.961	2.03±0.961	NOUN
bioscience-271	147	2	a	a	DET
bioscience-271	147	3	0.70±0.351a	0.70±0.351a	NUM
bioscience-271	147	4	1.43±0.372a	1.43±0.372a	NUM
bioscience-271	147	5	infiltration	infiltration	NOUN
bioscience-271	147	6	of	of	ADP
bioscience-271	147	7	mnc	mnc	PROPN
bioscience-271	147	8	2	2	NUM
bioscience-271	147	9	2.17±0.351a	2.17±0.351a	NUM
bioscience-271	147	10	1.23±0.731a	1.23±0.731a	NOUN
bioscience-271	147	11	2.17±0.601b	2.17±0.601b	PROPN
bioscience-271	148	1	3.10±1.161	3.10±1.161	PROPN
bioscience-271	148	2	b	b	PROPN
bioscience-271	148	3	0.67±0.431c	0.67±0.431c	NOUN
bioscience-271	149	1	1.50±0.901	1.50±0.901	PROPN
bioscience-271	149	2	a	a	DET
bioscience-271	149	3	0.43±0.391c	0.43±0.391c	NOUN
bioscience-271	150	1	1.47±0.352a	1.47±0.352a	NUM
bioscience-271	150	2	mid	mid	NOUN
bioscience-271	150	3	-	-	NOUN
bioscience-271	150	4	brain	brain	ADJ
bioscience-271	150	5	(	(	PUNCT
bioscience-271	150	6	optic	optic	ADJ
bioscience-271	150	7	tectum	tectum	NOUN
bioscience-271	150	8	)	)	PUNCT
bioscience-271	150	9	circulatory	circulatory	ADJ
bioscience-271	150	10	edematous	edematous	ADJ
bioscience-271	150	11	ot	ot	INTJ
bioscience-271	150	12	1	1	NUM
bioscience-271	150	13	0.70±0.171a	0.70±0.171a	NUM
bioscience-271	150	14	0.72±0.171a	0.72±0.171a	NUM
bioscience-271	150	15	0.73±0.211a	0.73±0.211a	NUM
bioscience-271	151	1	1.42±0.182	1.42±0.182	PROPN
bioscience-271	151	2	b	b	NOUN
bioscience-271	151	3	0.73±0.161a	0.73±0.161a	NUM
bioscience-271	151	4	1.00±0.241c	1.00±0.241c	NUM
bioscience-271	151	5	0.37±0.141b	0.37±0.141b	NOUN
bioscience-271	151	6	0.55±0.181a	0.55±0.181a	X
bioscience-271	151	7	regressive	regressive	ADJ
bioscience-271	151	8	lifting	lifting	NOUN
bioscience-271	151	9	of	of	ADP
bioscience-271	151	10	sl	sl	INTJ
bioscience-271	151	11	1	1	NUM
bioscience-271	151	12	0.80±0.131a	0.80±0.131a	NOUN
bioscience-271	151	13	0.70±0.231a	0.70±0.231a	NOUN
bioscience-271	151	14	0.68±0.171a	0.68±0.171a	PUNCT
bioscience-271	152	1	1.50±0.372	1.50±0.372	NUM
bioscience-271	153	1	b	b	NOUN
bioscience-271	153	2	0.43±0.231b	0.43±0.231b	NOUN
bioscience-271	153	3	1.02±0.282c	1.02±0.282c	NUM
bioscience-271	154	1	0.38±0.121b	0.38±0.121b	NOUN
bioscience-271	154	2	0.75±0.102a	0.75±0.102a	NOUN
bioscience-271	155	1	loosening	loosening	NOUN
bioscience-271	155	2	of	of	ADP
bioscience-271	155	3	dct	dct	PROPN
bioscience-271	155	4	1	1	NUM
bioscience-271	155	5	0.83±0.081a	0.83±0.081a	NUM
bioscience-271	155	6	0.72±0.121a	0.72±0.121a	ADJ
bioscience-271	155	7	0.67±0.151a	0.67±0.151a	NOUN
bioscience-271	156	1	1.18±0.332	1.18±0.332	X
bioscience-271	156	2	b	b	NOUN
bioscience-271	157	1	0.75±0.211a	0.75±0.211a	NOUN
bioscience-271	158	1	1.10±0.321	1.10±0.321	NUM
bioscience-271	158	2	a	a	DET
bioscience-271	158	3	b	b	PROPN
bioscience-271	158	4	0.47±0.101b	0.47±0.101b	NOUN
bioscience-271	158	5	0.72±0.182a	0.72±0.182a	PROPN
bioscience-271	159	1	spacing	spacing	NOUN
bioscience-271	159	2	of	of	ADP
bioscience-271	159	3	lct	lct	PROPN
bioscience-271	159	4	1	1	NUM
bioscience-271	159	5	0.85±0.211a	0.85±0.211a	NUM
bioscience-271	159	6	0.85±0.141a	0.85±0.141a	NOUN
bioscience-271	159	7	0.73±0.261ab	0.73±0.261ab	NOUN
bioscience-271	160	1	1.43±0.592	1.43±0.592	NUM
bioscience-271	160	2	b	b	NOUN
bioscience-271	160	3	0.65±0.141ab	0.65±0.141ab	NUM
bioscience-271	160	4	1.15±0.342	1.15±0.342	PROPN
bioscience-271	160	5	b	b	PROPN
bioscience-271	160	6	0.47±0.181b	0.47±0.181b	X
bioscience-271	160	7	0.83±0.182a	0.83±0.182a	ADJ
bioscience-271	160	8	vacuolation	vacuolation	NOUN
bioscience-271	160	9	2	2	NUM
bioscience-271	160	10	1.30±0.581a	1.30±0.581a	NOUN
bioscience-271	160	11	1.60±0.281a	1.60±0.281a	ADJ
bioscience-271	160	12	1.50±0.451a	1.50±0.451a	NOUN
bioscience-271	161	1	3.13±0.702	3.13±0.702	NUM
bioscience-271	161	2	b	b	PROPN
bioscience-271	161	3	1.30±0.451a	1.30±0.451a	PROPN
bioscience-271	161	4	2.50±1.062a	2.50±1.062a	PROPN
bioscience-271	161	5	b	b	PROPN
bioscience-271	161	6	0.97±0.231a	0.97±0.231a	ADJ
bioscience-271	161	7	1.13±0.241c	1.13±0.241c	NUM
bioscience-271	161	8	inflammatory	inflammatory	ADJ
bioscience-271	161	9	infiltration	infiltration	NOUN
bioscience-271	161	10	of	of	ADP
bioscience-271	161	11	lc	lc	PROPN
bioscience-271	161	12	2	2	NUM
bioscience-271	161	13	1.73±0.241a	1.73±0.241a	NUM
bioscience-271	161	14	1.63±0.291ab	1.63±0.291ab	NUM
bioscience-271	161	15	1.27±0.451ab	1.27±0.451ab	NUM
bioscience-271	161	16	1.30±0.681a	1.30±0.681a	NUM
bioscience-271	162	1	b	b	NUM
bioscience-271	162	2	0.83±0.611b	0.83±0.611b	NOUN
bioscience-271	163	1	1.73±0.332	1.73±0.332	PROPN
bioscience-271	163	2	a	a	DET
bioscience-271	163	3	0.57±0.151b	0.57±0.151b	NOUN
bioscience-271	163	4	1.03±0.232	1.03±0.232	NOUN
bioscience-271	163	5	b	b	NOUN
bioscience-271	164	1	cerebellum	cerebellum	NOUN
bioscience-271	164	2	(	(	PUNCT
bioscience-271	164	3	granular	granular	ADJ
bioscience-271	164	4	cell	cell	NOUN
bioscience-271	164	5	layer	layer	NOUN
bioscience-271	164	6	)	)	PUNCT
bioscience-271	164	7	regressive	regressive	ADJ
bioscience-271	164	8	lse	lse	NOUN
bioscience-271	164	9	2	2	NUM
bioscience-271	164	10	2.57±0.231a	2.57±0.231a	NUM
bioscience-271	164	11	2.40±0.181a	2.40±0.181a	NOUN
bioscience-271	164	12	2.20±0.331a	2.20±0.331a	NUM
bioscience-271	165	1	4.20±0.332	4.20±0.332	PROPN
bioscience-271	165	2	b	b	X
bioscience-271	165	3	0.47±0.101b	0.47±0.101b	PROPN
bioscience-271	166	1	1.93±0.532	1.93±0.532	PROPN
bioscience-271	167	1	a	a	DET
bioscience-271	167	2	0.90±0.281c	0.90±0.281c	NUM
bioscience-271	167	3	1.30±0.282c	1.30±0.282c	NUM
bioscience-271	167	4	lysis	lysis	NOUN
bioscience-271	167	5	of	of	ADP
bioscience-271	167	6	gc	gc	PROPN
bioscience-271	167	7	3	3	NUM
bioscience-271	167	8	3.75±0.311a	3.75±0.311a	NUM
bioscience-271	167	9	3.70±0.241a	3.70±0.241a	PROPN
bioscience-271	167	10	2.30±0.591b	2.30±0.591b	NOUN
bioscience-271	168	1	5.25±0.682	5.25±0.682	NUM
bioscience-271	168	2	b	b	NOUN
bioscience-271	168	3	0.65±0.121c	0.65±0.121c	NUM
bioscience-271	169	1	3.10±1.212	3.10±1.212	NUM
bioscience-271	169	2	a	a	DET
bioscience-271	169	3	1.25±0.351d	1.25±0.351d	NUM
bioscience-271	169	4	1.80±0.661c	1.80±0.661c	NUM
bioscience-271	169	5	necrotized	necrotized	ADJ
bioscience-271	169	6	area	area	NOUN
bioscience-271	169	7	3	3	NUM
bioscience-271	169	8	5.45±0.581a	5.45±0.581a	NUM
bioscience-271	169	9	5.30±0.411a	5.30±0.411a	NUM
bioscience-271	170	1	1.85±0.581b	1.85±0.581b	NUM
bioscience-271	171	1	5.45±0.962a	5.45±0.962a	NOUN
bioscience-271	172	1	1.35±0.161b	1.35±0.161b	PROPN
bioscience-271	173	1	3.25±1.362	3.25±1.362	NUM
bioscience-271	173	2	b	b	X
bioscience-271	173	3	1.35±0.311b	1.35±0.311b	NOUN
bioscience-271	173	4	1.80±0.421c	1.80±0.421c	NUM
bioscience-271	174	1	*	*	PUNCT
bioscience-271	174	2	as	as	ADP
bioscience-271	174	3	per	per	ADP
bioscience-271	174	4	the	the	DET
bioscience-271	174	5	descriptions	description	NOUN
bioscience-271	174	6	of	of	ADP
bioscience-271	174	7	bernet	bernet	NOUN
bioscience-271	174	8	et	et	PROPN
bioscience-271	174	9	al	al	PROPN
bioscience-271	174	10	.	.	PUNCT
bioscience-271	175	1	(	(	PUNCT
bioscience-271	175	2	1999	1999	NUM
bioscience-271	175	3	)	)	PUNCT
bioscience-271	175	4	.	.	PUNCT
bioscience-271	176	1	no	no	DET
bioscience-271	176	2	changes	change	NOUN
bioscience-271	176	3	were	be	AUX
bioscience-271	176	4	noted	note	VERB
bioscience-271	176	5	in	in	ADP
bioscience-271	176	6	the	the	DET
bioscience-271	176	7	control	control	NOUN
bioscience-271	176	8	group	group	NOUN
bioscience-271	176	9	.	.	PUNCT
bioscience-271	177	1	1	1	NUM
bioscience-271	177	2	-	-	SYM
bioscience-271	177	3	2	2	NUM
bioscience-271	177	4	:	:	PUNCT
bioscience-271	177	5	values	value	NOUN
bioscience-271	177	6	sharing	share	VERB
bioscience-271	177	7	a	a	DET
bioscience-271	177	8	common	common	ADJ
bioscience-271	177	9	numerical	numerical	ADJ
bioscience-271	177	10	superscript	superscript	PROPN
bioscience-271	177	11	for	for	ADP
bioscience-271	177	12	a	a	DET
bioscience-271	177	13	specific	specific	ADJ
bioscience-271	177	14	row	row	NOUN
bioscience-271	177	15	among	among	ADP
bioscience-271	177	16	the	the	DET
bioscience-271	177	17	treatment	treatment	NOUN
bioscience-271	177	18	groups	group	NOUN
bioscience-271	177	19	for	for	ADP
bioscience-271	177	20	a	a	DET
bioscience-271	177	21	specific	specific	ADJ
bioscience-271	177	22	day	day	NOUN
bioscience-271	177	23	differed	differ	VERB
bioscience-271	177	24	insignificantly	insignificantly	ADV
bioscience-271	177	25	(	(	PUNCT
bioscience-271	177	26	p>0.05	p>0.05	PROPN
bioscience-271	177	27	)	)	PUNCT
bioscience-271	177	28	.	.	PUNCT
bioscience-271	178	1	a	a	X
bioscience-271	178	2	-	-	PUNCT
bioscience-271	178	3	d	d	NOUN
bioscience-271	178	4	:	:	PUNCT
bioscience-271	178	5	values	value	NOUN
bioscience-271	178	6	sharing	share	VERB
bioscience-271	178	7	a	a	DET
bioscience-271	178	8	common	common	ADJ
bioscience-271	178	9	alphabetical	alphabetical	ADJ
bioscience-271	178	10	superscript	superscript	NOUN
bioscience-271	178	11	within	within	ADP
bioscience-271	178	12	a	a	DET
bioscience-271	178	13	row	row	NOUN
bioscience-271	178	14	for	for	ADP
bioscience-271	178	15	the	the	DET
bioscience-271	178	16	treated	treat	VERB
bioscience-271	178	17	group	group	NOUN
bioscience-271	178	18	on	on	ADP
bioscience-271	178	19	different	different	ADJ
bioscience-271	178	20	dpi	dpi	NOUN
bioscience-271	178	21	differed	differ	VERB
bioscience-271	178	22	insignificantly	insignificantly	ADV
bioscience-271	178	23	(	(	PUNCT
bioscience-271	178	24	p>0.05	p>0.05	PROPN
bioscience-271	178	25	)	)	PUNCT
bioscience-271	178	26	.	.	PUNCT
bioscience-271	179	1	a	a	X
bioscience-271	179	2	-	-	PUNCT
bioscience-271	179	3	c	c	NOUN
bioscience-271	179	4	:	:	PUNCT
bioscience-271	179	5	values	value	NOUN
bioscience-271	179	6	sharing	share	VERB
bioscience-271	179	7	a	a	DET
bioscience-271	179	8	common	common	ADJ
bioscience-271	179	9	alphabetical	alphabetical	ADJ
bioscience-271	179	10	superscript	superscript	NOUN
bioscience-271	179	11	within	within	ADP
bioscience-271	179	12	a	a	DET
bioscience-271	179	13	row	row	NOUN
bioscience-271	179	14	for	for	ADP
bioscience-271	179	15	the	the	DET
bioscience-271	179	16	untreated	untreated	ADJ
bioscience-271	179	17	group	group	NOUN
bioscience-271	179	18	on	on	ADP
bioscience-271	179	19	different	different	ADJ
bioscience-271	179	20	dpi	dpi	NOUN
bioscience-271	179	21	differed	differ	VERB
bioscience-271	179	22	insignificantly	insignificantly	ADV
bioscience-271	179	23	(	(	PUNCT
bioscience-271	179	24	p>0.05	p>0.05	PROPN
bioscience-271	179	25	)	)	PUNCT
bioscience-271	179	26	.	.	PUNCT
bioscience-271	180	1	dpi	dpi	NOUN
bioscience-271	180	2	:	:	PUNCT
bioscience-271	180	3	day	day	NOUN
bioscience-271	180	4	post	post	NOUN
bioscience-271	180	5	-	-	NOUN
bioscience-271	180	6	injection	injection	NOUN
bioscience-271	180	7	.	.	PUNCT
bioscience-271	181	1	if	if	SCONJ
bioscience-271	181	2	:	:	PUNCT
bioscience-271	181	3	importance	importance	NOUN
bioscience-271	181	4	factor	factor	NOUN
bioscience-271	181	5	;	;	PUNCT
bioscience-271	181	6	mp	mp	PROPN
bioscience-271	181	7	:	:	PUNCT
bioscience-271	181	8	meninx	meninx	PROPN
bioscience-271	181	9	primitiva	primitiva	PROPN
bioscience-271	181	10	;	;	PUNCT
bioscience-271	181	11	sl	sl	NUM
bioscience-271	181	12	:	:	PUNCT
bioscience-271	181	13	superficial	superficial	ADJ
bioscience-271	181	14	layer	layer	NOUN
bioscience-271	181	15	;	;	PUNCT
bioscience-271	181	16	lse	lse	PROPN
bioscience-271	181	17	:	:	PUNCT
bioscience-271	181	18	localized	localized	ADJ
bioscience-271	181	19	spongiform	spongiform	NOUN
bioscience-271	181	20	encephalopathy	encephalopathy	NOUN
bioscience-271	181	21	;	;	PUNCT
bioscience-271	181	22	bp	bp	PROPN
bioscience-271	181	23	:	:	PUNCT
bioscience-271	181	24	brain	brain	NOUN
bioscience-271	181	25	parenchyma	parenchyma	NOUN
bioscience-271	181	26	;	;	PUNCT
bioscience-271	181	27	mnc	mnc	PROPN
bioscience-271	181	28	:	:	PUNCT
bioscience-271	181	29	mononuclear	mononuclear	ADJ
bioscience-271	181	30	cells	cell	NOUN
bioscience-271	181	31	;	;	PUNCT
bioscience-271	181	32	ot	ot	NUM
bioscience-271	181	33	:	:	PUNCT
bioscience-271	181	34	optic	optic	ADJ
bioscience-271	181	35	tectum	tectum	NOUN
bioscience-271	181	36	;	;	PUNCT
bioscience-271	181	37	dct	dct	PROPN
bioscience-271	181	38	:	:	PUNCT
bioscience-271	181	39	loosened	loosen	VERB
bioscience-271	181	40	dense	dense	ADJ
bioscience-271	181	41	connective	connective	ADJ
bioscience-271	181	42	tissue	tissue	NOUN
bioscience-271	181	43	;	;	PUNCT
bioscience-271	181	44	lct	lct	PROPN
bioscience-271	181	45	:	:	PUNCT
bioscience-271	181	46	loose	loose	ADJ
bioscience-271	181	47	connective	connective	ADJ
bioscience-271	181	48	tissue	tissue	NOUN
bioscience-271	181	49	;	;	PUNCT
bioscience-271	181	50	lc	lc	NOUN
bioscience-271	181	51	:	:	PUNCT
bioscience-271	181	52	leucocytes	leucocyte	NOUN
bioscience-271	181	53	;	;	PUNCT
bioscience-271	181	54	gc	gc	PROPN
bioscience-271	181	55	:	:	PUNCT
bioscience-271	181	56	granular	granular	ADJ
bioscience-271	181	57	cells	cell	NOUN
bioscience-271	181	58	of	of	ADP
bioscience-271	181	59	the	the	DET
bioscience-271	181	60	cerebellum	cerebellum	NOUN
bioscience-271	181	61	.	.	PUNCT
bioscience-271	182	1	oa	oa	VERB
bioscience-271	182	2	-	-	PUNCT
bioscience-271	182	3	treated	treat	VERB
bioscience-271	182	4	group	group	NOUN
bioscience-271	182	5	,	,	PUNCT
bioscience-271	182	6	whereas	whereas	SCONJ
bioscience-271	182	7	the	the	DET
bioscience-271	182	8	untreated	untreated	ADJ
bioscience-271	182	9	group	group	NOUN
bioscience-271	182	10	presented	present	VERB
bioscience-271	182	11	more	more	ADV
bioscience-271	182	12	severe	severe	ADJ
bioscience-271	182	13	and	and	CCONJ
bioscience-271	182	14	persistent	persistent	ADJ
bioscience-271	182	15	damage	damage	NOUN
bioscience-271	182	16	.	.	PUNCT
bioscience-271	183	1	by	by	ADP
bioscience-271	183	2	dpi	dpi	PROPN
bioscience-271	183	3	21	21	NUM
bioscience-271	183	4	,	,	PUNCT
bioscience-271	183	5	both	both	DET
bioscience-271	183	6	groups	group	NOUN
bioscience-271	183	7	showed	show	VERB
bioscience-271	183	8	decreasing	decrease	VERB
bioscience-271	183	9	damage	damage	NOUN
bioscience-271	183	10	,	,	PUNCT
bioscience-271	183	11	with	with	ADP
bioscience-271	183	12	near	near	ADJ
bioscience-271	183	13	-	-	PUNCT
bioscience-271	183	14	normalization	normalization	NOUN
bioscience-271	183	15	of	of	ADP
bioscience-271	183	16	architecture	architecture	NOUN
bioscience-271	183	17	in	in	ADP
bioscience-271	183	18	the	the	DET
bioscience-271	183	19	oa	oa	ADV
bioscience-271	183	20	-	-	PUNCT
bioscience-271	183	21	treated	treat	VERB
bioscience-271	183	22	group	group	NOUN
bioscience-271	183	23	.	.	PUNCT
bioscience-271	184	1	in	in	ADP
bioscience-271	184	2	the	the	DET
bioscience-271	184	3	granular	granular	ADJ
bioscience-271	184	4	cell	cell	NOUN
bioscience-271	184	5	layer	layer	NOUN
bioscience-271	184	6	of	of	ADP
bioscience-271	184	7	the	the	DET
bioscience-271	184	8	cerebellum	cerebellum	NOUN
bioscience-271	184	9	,	,	PUNCT
bioscience-271	184	10	both	both	DET
bioscience-271	184	11	groups	group	NOUN
bioscience-271	184	12	experienced	experience	VERB
bioscience-271	184	13	regressive	regressive	ADJ
bioscience-271	184	14	changes	change	NOUN
bioscience-271	184	15	,	,	PUNCT
bioscience-271	184	16	including	include	VERB
bioscience-271	184	17	spongiform	spongiform	NOUN
bioscience-271	184	18	encephalopathy	encephalopathy	ADJ
bioscience-271	184	19	with	with	ADP
bioscience-271	184	20	vacuolation	vacuolation	NOUN
bioscience-271	184	21	and	and	CCONJ
bioscience-271	184	22	necrosis	necrosis	NOUN
bioscience-271	184	23	,	,	PUNCT
bioscience-271	184	24	which	which	PRON
bioscience-271	184	25	decreased	decrease	VERB
bioscience-271	184	26	with	with	ADP
bioscience-271	184	27	time	time	NOUN
bioscience-271	184	28	.	.	PUNCT
bioscience-271	185	1	on	on	ADP
bioscience-271	185	2	dpi	dpi	PROPN
bioscience-271	185	3	21	21	NUM
bioscience-271	185	4	,	,	PUNCT
bioscience-271	185	5	the	the	DET
bioscience-271	185	6	treated	treat	VERB
bioscience-271	185	7	group	group	NOUN
bioscience-271	185	8	displayed	display	VERB
bioscience-271	185	9	minimal	minimal	ADJ
bioscience-271	185	10	vacuolation	vacuolation	NOUN
bioscience-271	185	11	,	,	PUNCT
bioscience-271	185	12	while	while	SCONJ
bioscience-271	185	13	the	the	DET
bioscience-271	185	14	untreated	untreated	ADJ
bioscience-271	185	15	group	group	NOUN
bioscience-271	185	16	showed	show	VERB
bioscience-271	185	17	moderate	moderate	ADJ
bioscience-271	185	18	damage	damage	NOUN
bioscience-271	185	19	(	(	PUNCT
bioscience-271	185	20	figure	figure	NOUN
bioscience-271	185	21	3	3	NUM
bioscience-271	185	22	b	b	PROPN
bioscience-271	185	23	–	–	PUNCT
bioscience-271	185	24	i	i	NOUN
bioscience-271	185	25	;	;	PUNCT
bioscience-271	185	26	table	table	NOUN
bioscience-271	185	27	1	1	NUM
bioscience-271	185	28	)	)	PUNCT
bioscience-271	185	29	.	.	PUNCT
bioscience-271	186	1	overall	overall	ADV
bioscience-271	186	2	,	,	PUNCT
bioscience-271	186	3	the	the	DET
bioscience-271	186	4	oa	oa	ADV
bioscience-271	186	5	-	-	PUNCT
bioscience-271	186	6	treated	treat	VERB
bioscience-271	186	7	group	group	NOUN
bioscience-271	186	8	exhibited	exhibit	VERB
bioscience-271	186	9	less	less	ADJ
bioscience-271	186	10	damage	damage	NOUN
bioscience-271	186	11	,	,	PUNCT
bioscience-271	186	12	improved	improved	ADJ
bioscience-271	186	13	recovery	recovery	NOUN
bioscience-271	186	14	,	,	PUNCT
bioscience-271	186	15	and	and	CCONJ
bioscience-271	186	16	reduced	reduced	ADJ
bioscience-271	186	17	mortalities	mortality	NOUN
bioscience-271	186	18	(	(	PUNCT
bioscience-271	186	19	26	26	NUM
bioscience-271	186	20	%	%	NOUN
bioscience-271	186	21	;	;	PUNCT
bioscience-271	186	22	p	p	X
bioscience-271	186	23	>	>	X
bioscience-271	186	24	0.05	0.05	NUM
bioscience-271	186	25	)	)	PUNCT
bioscience-271	186	26	compared	compare	VERB
bioscience-271	186	27	to	to	ADP
bioscience-271	186	28	the	the	DET
bioscience-271	186	29	untreated	untreated	ADJ
bioscience-271	186	30	group	group	NOUN
bioscience-271	186	31	(	(	PUNCT
bioscience-271	186	32	32	32	NUM
bioscience-271	186	33	%	%	NOUN
bioscience-271	186	34	)	)	PUNCT
bioscience-271	186	35	.	.	PUNCT
bioscience-271	187	1	homology	homology	NOUN
bioscience-271	187	2	modelling	modelling	NOUN
bioscience-271	187	3	and	and	CCONJ
bioscience-271	187	4	molecular	molecular	ADJ
bioscience-271	187	5	docking	docking	NOUN
bioscience-271	187	6	using	use	VERB
bioscience-271	187	7	the	the	DET
bioscience-271	187	8	swiss	swiss	ADJ
bioscience-271	187	9	-	-	PUNCT
bioscience-271	187	10	model	model	NOUN
bioscience-271	187	11	server	server	NOUN
bioscience-271	187	12	,	,	PUNCT
bioscience-271	187	13	three	three	NUM
bioscience-271	187	14	-	-	PUNCT
bioscience-271	187	15	dimensional	dimensional	ADJ
bioscience-271	187	16	(	(	PUNCT
bioscience-271	187	17	3d	3d	NOUN
bioscience-271	187	18	)	)	PUNCT
bioscience-271	187	19	models	model	NOUN
bioscience-271	187	20	of	of	ADP
bioscience-271	187	21	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	187	22	and	and	CCONJ
bioscience-271	187	23	camp	camp	NOUN
bioscience-271	187	24	factor	factor	NOUN
bioscience-271	187	25	from	from	ADP
bioscience-271	187	26	s.	s.	PROPN
bioscience-271	187	27	agalactiae	agalactiae	PROPN
bioscience-271	187	28	were	be	AUX
bioscience-271	187	29	constructed	construct	VERB
bioscience-271	187	30	based	base	VERB
bioscience-271	187	31	on	on	ADP
bioscience-271	187	32	sequence	sequence	NOUN
bioscience-271	187	33	similarity	similarity	NOUN
bioscience-271	187	34	with	with	ADP
bioscience-271	187	35	identified	identify	VERB
bioscience-271	187	36	structural	structural	ADJ
bioscience-271	187	37	templates	template	NOUN
bioscience-271	187	38	.	.	PUNCT
bioscience-271	188	1	it	it	PRON
bioscience-271	188	2	is	be	AUX
bioscience-271	188	3	generally	generally	ADV
bioscience-271	188	4	important	important	ADJ
bioscience-271	188	5	to	to	PART
bioscience-271	188	6	note	note	VERB
bioscience-271	188	7	,	,	PUNCT
bioscience-271	188	8	in	in	ADP
bioscience-271	188	9	a	a	DET
bioscience-271	188	10	rather	rather	ADV
bioscience-271	188	11	typical	typical	ADJ
bioscience-271	188	12	and	and	CCONJ
bioscience-271	188	13	somewhat	somewhat	ADV
bioscience-271	188	14	broadly	broadly	ADV
bioscience-271	188	15	consistent	consistent	ADJ
bioscience-271	188	16	and	and	CCONJ
bioscience-271	188	17	commonly	commonly	ADV
bioscience-271	188	18	recognised	recognise	VERB
bioscience-271	188	19	manner	manner	NOUN
bioscience-271	188	20	,	,	PUNCT
bioscience-271	188	21	that	that	SCONJ
bioscience-271	188	22	this	this	DET
bioscience-271	188	23	modelling	modelling	NOUN
bioscience-271	188	24	approach	approach	NOUN
bioscience-271	188	25	essentially	essentially	ADV
bioscience-271	188	26	follows	follow	VERB
bioscience-271	188	27	a	a	DET
bioscience-271	188	28	broadly	broadly	ADV
bioscience-271	188	29	conventional	conventional	ADJ
bioscience-271	188	30	and	and	CCONJ
bioscience-271	188	31	widely	widely	ADV
bioscience-271	188	32	accepted	accept	VERB
bioscience-271	188	33	procedure	procedure	NOUN
bioscience-271	188	34	overall	overall	ADJ
bioscience-271	188	35	.	.	PUNCT
bioscience-271	189	1	the	the	DET
bioscience-271	189	2	models	model	NOUN
bioscience-271	189	3	generated	generate	VERB
bioscience-271	189	4	from	from	ADP
bioscience-271	189	5	templates	template	NOUN
bioscience-271	189	6	with	with	ADP
bioscience-271	189	7	the	the	DET
bioscience-271	189	8	highest	high	ADJ
bioscience-271	189	9	sequence	sequence	NOUN
bioscience-271	189	10	identity	identity	NOUN
bioscience-271	189	11	are	be	AUX
bioscience-271	189	12	presented	present	VERB
bioscience-271	189	13	in	in	ADP
bioscience-271	189	14	(	(	PUNCT
bioscience-271	189	15	figure	figure	NOUN
bioscience-271	189	16	4	4	NUM
bioscience-271	189	17	a1	a1	NOUN
bioscience-271	189	18	,	,	PUNCT
bioscience-271	189	19	b1	b1	NOUN
bioscience-271	189	20	)	)	PUNCT
bioscience-271	189	21	.	.	PUNCT
bioscience-271	190	1	this	this	DET
bioscience-271	190	2	approach	approach	NOUN
bioscience-271	190	3	,	,	PUNCT
bioscience-271	190	4	in	in	ADP
bioscience-271	190	5	many	many	ADJ
bioscience-271	190	6	ways	way	NOUN
bioscience-271	190	7	,	,	PUNCT
bioscience-271	190	8	essentially	essentially	ADV
bioscience-271	190	9	leverages	leverage	VERB
bioscience-271	190	10	the	the	DET
bioscience-271	190	11	inherent	inherent	ADJ
bioscience-271	190	12	structural	structural	ADJ
bioscience-271	190	13	similarity	similarity	NOUN
bioscience-271	190	14	among	among	ADP
bioscience-271	190	15	proteins	protein	NOUN
bioscience-271	190	16	of	of	ADP
bioscience-271	190	17	the	the	DET
bioscience-271	190	18	same	same	ADJ
bioscience-271	190	19	family	family	NOUN
bioscience-271	190	20	,	,	PUNCT
bioscience-271	190	21	which	which	PRON
bioscience-271	190	22	usually	usually	ADV
bioscience-271	190	23	tend	tend	VERB
bioscience-271	190	24	to	to	PART
bioscience-271	190	25	share	share	VERB
bioscience-271	190	26	broadly	broadly	ADV
bioscience-271	190	27	comparable	comparable	ADJ
bioscience-271	190	28	and	and	CCONJ
bioscience-271	190	29	functionally	functionally	ADV
bioscience-271	190	30	related	relate	VERB
bioscience-271	190	31	three	three	NUM
bioscience-271	190	32	-	-	PUNCT
bioscience-271	190	33	dimensional	dimensional	ADJ
bioscience-271	190	34	architectures	architecture	NOUN
bioscience-271	190	35	.	.	PUNCT
bioscience-271	191	1	the	the	DET
bioscience-271	191	2	outcomes	outcome	NOUN
bioscience-271	191	3	of	of	ADP
bioscience-271	191	4	the	the	DET
bioscience-271	191	5	homology	homology	NOUN
bioscience-271	191	6	modelling	modelling	NOUN
bioscience-271	191	7	are	be	AUX
bioscience-271	191	8	,	,	PUNCT
bioscience-271	191	9	more	more	ADV
bioscience-271	191	10	or	or	CCONJ
bioscience-271	191	11	less	less	ADJ
bioscience-271	191	12	,	,	PUNCT
bioscience-271	191	13	conveniently	conveniently	ADV
bioscience-271	191	14	summarised	summarise	VERB
bioscience-271	191	15	in	in	ADP
bioscience-271	191	16	(	(	PUNCT
bioscience-271	191	17	table	table	NOUN
bioscience-271	191	18	2	2	NUM
bioscience-271	191	19	)	)	PUNCT
bioscience-271	191	20	.	.	PUNCT
bioscience-271	192	1	the	the	DET
bioscience-271	192	2	global	global	ADJ
bioscience-271	192	3	model	model	PROPN
bioscience-271	192	4	quality	quality	PROPN
bioscience-271	192	5	estimation	estimation	NOUN
bioscience-271	192	6	(	(	PUNCT
bioscience-271	192	7	gmqe	gmqe	NOUN
bioscience-271	192	8	)	)	PUNCT
bioscience-271	192	9	and	and	CCONJ
bioscience-271	192	10	qualitative	qualitative	ADJ
bioscience-271	192	11	model	model	NOUN
bioscience-271	192	12	energy	energy	NOUN
bioscience-271	192	13	analysis	analysis	NOUN
bioscience-271	192	14	(	(	PUNCT
bioscience-271	192	15	qmean	qmean	ADJ
bioscience-271	192	16	)	)	PUNCT
bioscience-271	192	17	scores	score	NOUN
bioscience-271	192	18	were	be	AUX
bioscience-271	192	19	high	high	ADJ
bioscience-271	192	20	,	,	PUNCT
bioscience-271	192	21	corresponding	correspond	VERB
bioscience-271	192	22	to	to	ADP
bioscience-271	192	23	higher	high	ADJ
bioscience-271	192	24	sequence	sequence	NOUN
bioscience-271	192	25	identity	identity	NOUN
bioscience-271	192	26	with	with	ADP
bioscience-271	192	27	templates	template	NOUN
bioscience-271	192	28	.	.	PUNCT
bioscience-271	193	1	the	the	DET
bioscience-271	193	2	generated	generate	VERB
bioscience-271	193	3	models	model	NOUN
bioscience-271	193	4	exhibited	exhibit	VERB
bioscience-271	193	5	optimal	optimal	ADJ
bioscience-271	193	6	quality	quality	NOUN
bioscience-271	193	7	,	,	PUNCT
bioscience-271	193	8	as	as	SCONJ
bioscience-271	193	9	validated	validate	VERB
bioscience-271	193	10	by	by	ADP
bioscience-271	193	11	swiss	swiss	ADJ
bioscience-271	193	12	-	-	PUNCT
bioscience-271	193	13	model	model	NOUN
bioscience-271	193	14	,	,	PUNCT
bioscience-271	193	15	with	with	ADP
bioscience-271	193	16	molprobity	molprobity	NOUN
bioscience-271	193	17	scores	score	NOUN
bioscience-271	193	18	above	above	ADP
bioscience-271	193	19	0.66	0.66	NUM
bioscience-271	193	20	,	,	PUNCT
bioscience-271	193	21	and	and	CCONJ
bioscience-271	193	22	were	be	AUX
bioscience-271	193	23	considered	consider	VERB
bioscience-271	193	24	excellent	excellent	ADJ
bioscience-271	193	25	.	.	PUNCT
bioscience-271	194	1	nearly	nearly	ADV
bioscience-271	194	2	98	98	NUM
bioscience-271	194	3	%	%	NOUN
bioscience-271	194	4	of	of	ADP
bioscience-271	194	5	residues	residue	NOUN
bioscience-271	194	6	were	be	AUX
bioscience-271	194	7	located	locate	VERB
bioscience-271	194	8	in	in	ADP
bioscience-271	194	9	the	the	DET
bioscience-271	194	10	favoured	favour	VERB
bioscience-271	194	11	regions	region	NOUN
bioscience-271	194	12	of	of	ADP
bioscience-271	194	13	the	the	DET
bioscience-271	194	14	ramachandran	ramachandran	PROPN
bioscience-271	194	15	plot	plot	NOUN
bioscience-271	194	16	(	(	PUNCT
bioscience-271	194	17	figure	figure	NOUN
bioscience-271	194	18	4	4	NUM
bioscience-271	194	19	a2	a2	NOUN
bioscience-271	194	20	,	,	PUNCT
bioscience-271	194	21	b2	b2	NOUN
bioscience-271	194	22	)	)	PUNCT
bioscience-271	194	23	.	.	PUNCT
bioscience-271	195	1	the	the	DET
bioscience-271	195	2	ligand	ligand	NOUN
bioscience-271	195	3	oa	oa	PRON
bioscience-271	195	4	exhibited	exhibit	VERB
bioscience-271	195	5	notable	notable	ADJ
bioscience-271	195	6	binding	bind	VERB
bioscience-271	195	7	affinities	affinity	NOUN
bioscience-271	195	8	toward	toward	ADP
bioscience-271	195	9	both	both	PRON
bioscience-271	195	10	glycosyltransferase	glycosyltransferase	VERB
bioscience-271	195	11	and	and	CCONJ
bioscience-271	195	12	camp	camp	NOUN
bioscience-271	195	13	factor	factor	NOUN
bioscience-271	195	14	,	,	PUNCT
bioscience-271	195	15	with	with	ADP
bioscience-271	195	16	docking	docking	NOUN
bioscience-271	195	17	scores	score	NOUN
bioscience-271	195	18	of	of	ADP
bioscience-271	195	19	–	–	PUNCT
bioscience-271	195	20	4.99	4.99	NUM
bioscience-271	195	21	and	and	CCONJ
bioscience-271	195	22	–	–	PUNCT
bioscience-271	195	23	4.31	4.31	NUM
bioscience-271	195	24	kcal	kcal	NOUN
bioscience-271	195	25	/	/	SYM
bioscience-271	195	26	mol	mol	NOUN
bioscience-271	195	27	,	,	PUNCT
bioscience-271	195	28	respectively	respectively	ADV
bioscience-271	195	29	.	.	PUNCT
bioscience-271	196	1	these	these	DET
bioscience-271	196	2	interactions	interaction	NOUN
bioscience-271	196	3	were	be	AUX
bioscience-271	196	4	supported	support	VERB
bioscience-271	196	5	,	,	PUNCT
bioscience-271	196	6	in	in	ADP
bioscience-271	196	7	a	a	DET
bioscience-271	196	8	fairly	fairly	ADV
bioscience-271	196	9	straightforward	straightforward	ADJ
bioscience-271	196	10	and	and	CCONJ
bioscience-271	196	11	somewhat	somewhat	ADV
bioscience-271	196	12	broadly	broadly	ADV
bioscience-271	196	13	descriptive	descriptive	ADJ
bioscience-271	196	14	and	and	CCONJ
bioscience-271	196	15	methodologically	methodologically	ADV
bioscience-271	196	16	consistent	consistent	ADJ
bioscience-271	196	17	manner	manner	NOUN
bioscience-271	196	18	,	,	PUNCT
bioscience-271	196	19	by	by	ADP
bioscience-271	196	20	multiple	multiple	ADJ
bioscience-271	196	21	hydrogen	hydrogen	NOUN
bioscience-271	196	22	bonds	bond	NOUN
bioscience-271	196	23	and	and	CCONJ
bioscience-271	196	24	close	close	ADJ
bioscience-271	196	25	-	-	PUNCT
bioscience-271	196	26	contact	contact	NOUN
bioscience-271	196	27	residues	residue	NOUN
bioscience-271	196	28	,	,	PUNCT
bioscience-271	196	29	suggesting	suggest	VERB
bioscience-271	196	30	generally	generally	ADV
bioscience-271	196	31	stable	stable	ADJ
bioscience-271	196	32	and	and	CCONJ
bioscience-271	196	33	favourable	favourable	ADJ
bioscience-271	196	34	binding	binding	ADJ
bioscience-271	196	35	conformations	conformation	NOUN
bioscience-271	196	36	(	(	PUNCT
bioscience-271	196	37	table	table	NOUN
bioscience-271	196	38	3	3	NUM
bioscience-271	196	39	;	;	PUNCT
bioscience-271	196	40	figure	figure	VERB
bioscience-271	196	41	5	5	NUM
bioscience-271	196	42	a	a	PRON
bioscience-271	196	43	,	,	PUNCT
bioscience-271	196	44	b	b	NOUN
bioscience-271	196	45	)	)	PUNCT
bioscience-271	196	46	.	.	PUNCT
bioscience-271	197	1	highlights	highlight	NOUN
bioscience-271	197	2	in	in	ADP
bioscience-271	197	3	bioscience	bioscience	NOUN
bioscience-271	197	4	page	page	NOUN
bioscience-271	197	5	5	5	NUM
bioscience-271	197	6	of	of	ADP
bioscience-271	197	7	10	10	NUM
bioscience-271	197	8	october	october	PROPN
bioscience-271	197	9	2025|volume	2025|volume	NUM
bioscience-271	197	10	8	8	NUM
bioscience-271	197	11	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	197	12	sinha	sinha	PROPN
bioscience-271	197	13	p	p	PROPN
bioscience-271	197	14	et	et	PROPN
bioscience-271	197	15	al	al	PROPN
bioscience-271	197	16	.	.	PROPN
bioscience-271	197	17	,	,	PUNCT
bioscience-271	197	18	2025	2025	NUM
bioscience-271	197	19	effect	effect	NOUN
bioscience-271	197	20	of	of	ADP
bioscience-271	197	21	oxolinic	oxolinic	ADJ
bioscience-271	197	22	acid	acid	NOUN
bioscience-271	197	23	therapy	therapy	NOUN
bioscience-271	197	24	table	table	NOUN
bioscience-271	197	25	2	2	NUM
bioscience-271	197	26	.	.	PUNCT
bioscience-271	197	27	homology	homology	NOUN
bioscience-271	197	28	modelling	model	VERB
bioscience-271	197	29	data	datum	NOUN
bioscience-271	197	30	of	of	ADP
bioscience-271	197	31	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	197	32	aam99596	aam99596	NOUN
bioscience-271	197	33	and	and	CCONJ
bioscience-271	197	34	camp	camp	NOUN
bioscience-271	197	35	factor	factor	NOUN
bioscience-271	197	36	aki96324	aki96324	NOUN
bioscience-271	197	37	of	of	ADP
bioscience-271	197	38	streptococcus	streptococcus	NOUN
bioscience-271	197	39	agalactiae	agalactiae	PROPN
bioscience-271	197	40	computed	compute	VERB
bioscience-271	197	41	using	use	VERB
bioscience-271	197	42	swiss	swiss	ADJ
bioscience-271	197	43	model	model	NOUN
bioscience-271	197	44	.	.	PUNCT
bioscience-271	198	1	characteristics	characteristic	NOUN
bioscience-271	198	2	glycosyltransferase	glycosyltransferase	PROPN
bioscience-271	198	3	aam99596	aam99596	PROPN
bioscience-271	198	4	camp	camp	PROPN
bioscience-271	198	5	factor	factor	NOUN
bioscience-271	198	6	aki96324	aki96324	NOUN
bioscience-271	198	7	template	template	NOUN
bioscience-271	198	8	i	i	PROPN
bioscience-271	198	9	d	d	PROPN
bioscience-271	198	10	a0a4v0ha53.1.a	a0a4v0ha53.1.a	X
bioscience-271	199	1	5h6i.1.a	5h6i.1.a	NUM
bioscience-271	199	2	sequence	sequence	NOUN
bioscience-271	199	3	identity	identity	NOUN
bioscience-271	199	4	(	(	PUNCT
bioscience-271	199	5	%	%	NOUN
bioscience-271	199	6	)	)	PUNCT
bioscience-271	199	7	71.69	71.69	NUM
bioscience-271	199	8	100	100	NUM
bioscience-271	199	9	qmean	qmean	ADJ
bioscience-271	199	10	0.90	0.90	NUM
bioscience-271	199	11	0.86	0.86	NUM
bioscience-271	199	12	gmqe	gmqe	NOUN
bioscience-271	199	13	0.96	0.96	NUM
bioscience-271	199	14	0.80	0.80	NUM
bioscience-271	199	15	molprobity	molprobity	NOUN
bioscience-271	199	16	score	score	NOUN
bioscience-271	199	17	0.91	0.91	NUM
bioscience-271	199	18	0.70	0.70	NUM
bioscience-271	199	19	ramachandran	ramachandran	NOUN
bioscience-271	199	20	plot	plot	NOUN
bioscience-271	199	21	–	–	PUNCT
bioscience-271	199	22	favoured	favour	VERB
bioscience-271	199	23	region	region	NOUN
bioscience-271	199	24	(	(	PUNCT
bioscience-271	199	25	%	%	INTJ
bioscience-271	199	26	)	)	PUNCT
bioscience-271	199	27	96.97	96.97	NUM
bioscience-271	199	28	98.12	98.12	NUM
bioscience-271	199	29	ramachandran	ramachandran	PROPN
bioscience-271	199	30	plot	plot	NOUN
bioscience-271	199	31	–	–	PUNCT
bioscience-271	199	32	outlier	outlier	NOUN
bioscience-271	199	33	region	region	NOUN
bioscience-271	199	34	(	(	PUNCT
bioscience-271	199	35	%	%	NOUN
bioscience-271	199	36	)	)	PUNCT
bioscience-271	199	37	0.00	0.00	NUM
bioscience-271	199	38	0.00	0.00	NUM
bioscience-271	199	39	qmean	qmean	ADJ
bioscience-271	199	40	:	:	PUNCT
bioscience-271	199	41	qualitative	qualitative	ADJ
bioscience-271	199	42	model	model	NOUN
bioscience-271	199	43	energy	energy	NOUN
bioscience-271	199	44	analysis	analysis	NOUN
bioscience-271	199	45	;	;	PUNCT
bioscience-271	199	46	gmqe	gmqe	NOUN
bioscience-271	199	47	:	:	PUNCT
bioscience-271	199	48	global	global	ADJ
bioscience-271	199	49	model	model	NOUN
bioscience-271	199	50	quality	quality	NOUN
bioscience-271	199	51	estimation	estimation	NOUN
bioscience-271	199	52	.	.	PUNCT
bioscience-271	200	1	discussions	discussion	NOUN
bioscience-271	200	2	in	in	ADP
bioscience-271	200	3	terms	term	NOUN
bioscience-271	200	4	of	of	ADP
bioscience-271	200	5	virulence	virulence	NOUN
bioscience-271	200	6	,	,	PUNCT
bioscience-271	200	7	the	the	DET
bioscience-271	200	8	sa	sa	PROPN
bioscience-271	200	9	strain	strain	PROPN
bioscience-271	200	10	,	,	PUNCT
bioscience-271	200	11	isolated	isolate	VERB
bioscience-271	200	12	from	from	ADP
bioscience-271	200	13	the	the	DET
bioscience-271	200	14	kidney	kidney	NOUN
bioscience-271	200	15	of	of	ADP
bioscience-271	200	16	asian	asian	ADJ
bioscience-271	200	17	seabass	seabass	NOUN
bioscience-271	200	18	lates	late	NOUN
bioscience-271	200	19	calcarifer	calcarifer	NOUN
bioscience-271	200	20	,	,	PUNCT
bioscience-271	200	21	was	be	AUX
bioscience-271	200	22	borderline	borderline	ADJ
bioscience-271	200	23	avirulent	avirulent	NOUN
bioscience-271	200	24	to	to	ADP
bioscience-271	200	25	weakly	weakly	ADJ
bioscience-271	200	26	virulent	virulent	NOUN
bioscience-271	200	27	[	[	X
bioscience-271	200	28	7	7	NUM
bioscience-271	200	29	;	;	PUNCT
bioscience-271	200	30	37	37	NUM
bioscience-271	200	31	;	;	PUNCT
bioscience-271	200	32	38	38	NUM
bioscience-271	200	33	]	]	PUNCT
bioscience-271	200	34	with	with	ADP
bioscience-271	200	35	a	a	DET
bioscience-271	200	36	moderately	moderately	ADV
bioscience-271	200	37	high	high	ADJ
bioscience-271	200	38	mic	mic	NOUN
bioscience-271	200	39	for	for	ADP
bioscience-271	200	40	oa	oa	PROPN
bioscience-271	200	41	.	.	PROPN
bioscience-271	200	42	sa	sa	PROPN
bioscience-271	200	43	affects	affect	VERB
bioscience-271	200	44	the	the	DET
bioscience-271	200	45	brain	brain	NOUN
bioscience-271	200	46	using	use	VERB
bioscience-271	200	47	several	several	ADJ
bioscience-271	200	48	virulence	virulence	NOUN
bioscience-271	200	49	factors	factor	NOUN
bioscience-271	200	50	to	to	PART
bioscience-271	200	51	allow	allow	VERB
bioscience-271	200	52	the	the	DET
bioscience-271	200	53	infection	infection	NOUN
bioscience-271	200	54	process	process	NOUN
bioscience-271	200	55	[	[	X
bioscience-271	200	56	4	4	NUM
bioscience-271	200	57	;	;	PUNCT
bioscience-271	200	58	38	38	NUM
bioscience-271	200	59	;	;	PUNCT
bioscience-271	200	60	39	39	NUM
bioscience-271	200	61	]	]	PUNCT
bioscience-271	200	62	.	.	PUNCT
bioscience-271	201	1	in	in	ADP
bioscience-271	201	2	this	this	DET
bioscience-271	201	3	study	study	NOUN
bioscience-271	201	4	,	,	PUNCT
bioscience-271	201	5	sa	sa	PROPN
bioscience-271	201	6	resulted	result	VERB
bioscience-271	201	7	in	in	ADP
bioscience-271	201	8	systemic	systemic	ADJ
bioscience-271	201	9	pathological	pathological	ADJ
bioscience-271	201	10	alterations	alteration	NOUN
bioscience-271	201	11	,	,	PUNCT
bioscience-271	201	12	including	include	VERB
bioscience-271	201	13	inflammation	inflammation	NOUN
bioscience-271	201	14	,	,	PUNCT
bioscience-271	201	15	haemorrhages	haemorrhage	NOUN
bioscience-271	201	16	,	,	PUNCT
bioscience-271	201	17	and	and	CCONJ
bioscience-271	201	18	meningitis	meningitis	NOUN
bioscience-271	201	19	in	in	ADP
bioscience-271	201	20	challenged	challenge	VERB
bioscience-271	201	21	fish	fish	NOUN
bioscience-271	201	22	,	,	PUNCT
bioscience-271	201	23	as	as	ADP
bioscience-271	201	24	in	in	ADP
bioscience-271	201	25	previous	previous	ADJ
bioscience-271	201	26	research	research	NOUN
bioscience-271	201	27	[	[	X
bioscience-271	201	28	5	5	NUM
bioscience-271	201	29	;	;	PUNCT
bioscience-271	201	30	6	6	NUM
bioscience-271	201	31	;	;	PUNCT
bioscience-271	201	32	7	7	NUM
bioscience-271	201	33	;	;	PUNCT
bioscience-271	201	34	8	8	NUM
bioscience-271	201	35	;	;	PUNCT
bioscience-271	201	36	9	9	NUM
bioscience-271	201	37	]	]	PUNCT
bioscience-271	201	38	.	.	PUNCT
bioscience-271	202	1	the	the	DET
bioscience-271	202	2	sa	sa	NOUN
bioscience-271	202	3	-	-	PUNCT
bioscience-271	202	4	infected	infect	VERB
bioscience-271	202	5	fish	fish	NOUN
bioscience-271	202	6	also	also	ADV
bioscience-271	202	7	exhibited	exhibit	VERB
bioscience-271	202	8	aberrant	aberrant	ADJ
bioscience-271	202	9	swimming	swimming	NOUN
bioscience-271	202	10	,	,	PUNCT
bioscience-271	202	11	marked	mark	VERB
bioscience-271	202	12	by	by	ADP
bioscience-271	202	13	circular	circular	ADJ
bioscience-271	202	14	movement	movement	NOUN
bioscience-271	202	15	and	and	CCONJ
bioscience-271	202	16	c	c	NOUN
bioscience-271	202	17	-	-	PUNCT
bioscience-271	202	18	shaped	shape	VERB
bioscience-271	202	19	body	body	NOUN
bioscience-271	202	20	bending	bending	NOUN
bioscience-271	202	21	.	.	PUNCT
bioscience-271	203	1	it	it	PRON
bioscience-271	203	2	could	could	AUX
bioscience-271	203	3	be	be	AUX
bioscience-271	203	4	due	due	ADJ
bioscience-271	203	5	to	to	ADP
bioscience-271	203	6	the	the	DET
bioscience-271	203	7	possible	possible	ADJ
bioscience-271	203	8	neurological	neurological	ADJ
bioscience-271	203	9	problem	problem	NOUN
bioscience-271	203	10	,	,	PUNCT
bioscience-271	203	11	as	as	SCONJ
bioscience-271	203	12	the	the	DET
bioscience-271	203	13	midbrain	midbrain	NOUN
bioscience-271	203	14	reportedly	reportedly	ADV
bioscience-271	203	15	controls	control	VERB
bioscience-271	203	16	fish	fish	NOUN
bioscience-271	203	17	swimming	swim	VERB
bioscience-271	203	18	by	by	ADP
bioscience-271	203	19	transmitting	transmit	VERB
bioscience-271	203	20	axons	axon	NOUN
bioscience-271	203	21	to	to	PART
bioscience-271	203	22	innervate	innervate	VERB
bioscience-271	203	23	the	the	DET
bioscience-271	203	24	spinal	spinal	NOUN
bioscience-271	203	25	cord	cord	NOUN
bioscience-271	203	26	’s	’s	PART
bioscience-271	203	27	primary	primary	ADJ
bioscience-271	203	28	and	and	CCONJ
bioscience-271	203	29	secondary	secondary	ADJ
bioscience-271	203	30	motor	motor	NOUN
bioscience-271	203	31	neurons	neuron	NOUN
bioscience-271	204	1	[	[	X
bioscience-271	204	2	9	9	NUM
bioscience-271	204	3	;	;	PUNCT
bioscience-271	204	4	40	40	NUM
bioscience-271	204	5	]	]	PUNCT
bioscience-271	204	6	.	.	PUNCT
bioscience-271	205	1	further	far	ADV
bioscience-271	205	2	,	,	PUNCT
bioscience-271	205	3	abnormal	abnormal	ADJ
bioscience-271	205	4	swimming	swimming	NOUN
bioscience-271	205	5	behaviours	behaviour	NOUN
bioscience-271	205	6	due	due	ADP
bioscience-271	205	7	to	to	ADP
bioscience-271	205	8	streptococcal	streptococcal	ADJ
bioscience-271	205	9	infections	infection	NOUN
bioscience-271	205	10	were	be	AUX
bioscience-271	205	11	linked	link	VERB
bioscience-271	205	12	to	to	ADP
bioscience-271	205	13	brain	brain	NOUN
bioscience-271	205	14	fluid	fluid	ADJ
bioscience-271	205	15	accumulation	accumulation	NOUN
bioscience-271	205	16	[	[	X
bioscience-271	205	17	7	7	NUM
bioscience-271	205	18	]	]	PUNCT
bioscience-271	205	19	.	.	PUNCT
bioscience-271	206	1	in	in	ADP
bioscience-271	206	2	this	this	DET
bioscience-271	206	3	work	work	NOUN
bioscience-271	206	4	,	,	PUNCT
bioscience-271	206	5	we	we	PRON
bioscience-271	206	6	isolated	isolate	VERB
bioscience-271	206	7	sa	sa	NOUN
bioscience-271	206	8	from	from	ADP
bioscience-271	206	9	the	the	DET
bioscience-271	206	10	brain	brain	NOUN
bioscience-271	206	11	tissues	tissue	NOUN
bioscience-271	206	12	of	of	ADP
bioscience-271	206	13	challenged	challenge	VERB
bioscience-271	206	14	tilapias	tilapia	NOUN
bioscience-271	206	15	on	on	ADP
bioscience-271	206	16	bhia	bhia	NOUN
bioscience-271	206	17	,	,	PUNCT
bioscience-271	206	18	indicating	indicate	VERB
bioscience-271	206	19	a	a	DET
bioscience-271	206	20	breach	breach	NOUN
bioscience-271	206	21	of	of	ADP
bioscience-271	206	22	the	the	DET
bioscience-271	206	23	bbb	bbb	PROPN
bioscience-271	206	24	.	.	PUNCT
bioscience-271	207	1	sa	sa	PROPN
bioscience-271	207	2	employ	employ	VERB
bioscience-271	207	3	various	various	ADJ
bioscience-271	207	4	strategies	strategy	NOUN
bioscience-271	207	5	to	to	PART
bioscience-271	207	6	survive	survive	VERB
bioscience-271	207	7	in	in	ADP
bioscience-271	207	8	the	the	DET
bioscience-271	207	9	bloodstream	bloodstream	NOUN
bioscience-271	207	10	,	,	PUNCT
bioscience-271	207	11	colonize	colonize	VERB
bioscience-271	207	12	brain	brain	NOUN
bioscience-271	207	13	vasculature	vasculature	NOUN
bioscience-271	207	14	,	,	PUNCT
bioscience-271	207	15	and	and	CCONJ
bioscience-271	207	16	cross	cross	VERB
bioscience-271	207	17	the	the	DET
bioscience-271	207	18	bbb	bbb	NOUN
bioscience-271	208	1	[	[	X
bioscience-271	208	2	41	41	NUM
bioscience-271	208	3	]	]	PUNCT
bioscience-271	208	4	.	.	PUNCT
bioscience-271	209	1	the	the	DET
bioscience-271	209	2	results	result	NOUN
bioscience-271	209	3	indicated	indicate	VERB
bioscience-271	209	4	that	that	SCONJ
bioscience-271	209	5	the	the	DET
bioscience-271	209	6	sa	sa	NOUN
bioscience-271	209	7	can	can	AUX
bioscience-271	209	8	enter	enter	VERB
bioscience-271	209	9	the	the	DET
bioscience-271	209	10	brain	brain	NOUN
bioscience-271	209	11	parenchyma	parenchyma	NOUN
bioscience-271	209	12	by	by	ADP
bioscience-271	209	13	destroying	destroy	VERB
bioscience-271	209	14	the	the	DET
bioscience-271	209	15	host	host	NOUN
bioscience-271	209	16	bbb	bbb	NOUN
bioscience-271	209	17	and	and	CCONJ
bioscience-271	209	18	causing	cause	VERB
bioscience-271	209	19	localized	localized	ADJ
bioscience-271	209	20	spongiform	spongiform	NOUN
bioscience-271	209	21	encephalopathy	encephalopathy	ADJ
bioscience-271	209	22	.	.	PUNCT
bioscience-271	210	1	several	several	ADJ
bioscience-271	210	2	earlier	early	ADJ
bioscience-271	210	3	studies	study	NOUN
bioscience-271	210	4	confirmed	confirm	VERB
bioscience-271	210	5	the	the	DET
bioscience-271	210	6	establishment	establishment	NOUN
bioscience-271	210	7	of	of	ADP
bioscience-271	210	8	sa	sa	PROPN
bioscience-271	211	1	[	[	X
bioscience-271	211	2	6	6	NUM
bioscience-271	211	3	;	;	PUNCT
bioscience-271	211	4	8	8	NUM
bioscience-271	211	5	;	;	PUNCT
bioscience-271	211	6	42	42	NUM
bioscience-271	211	7	]	]	PUNCT
bioscience-271	211	8	or	or	CCONJ
bioscience-271	211	9	biofilm	biofilm	NOUN
bioscience-271	211	10	formation	formation	NOUN
bioscience-271	211	11	[	[	X
bioscience-271	211	12	43	43	NUM
bioscience-271	211	13	]	]	PUNCT
bioscience-271	211	14	in	in	ADP
bioscience-271	211	15	fish	fish	NOUN
bioscience-271	211	16	brains	brain	NOUN
bioscience-271	211	17	.	.	PUNCT
bioscience-271	212	1	when	when	SCONJ
bioscience-271	212	2	the	the	DET
bioscience-271	212	3	bacteria	bacteria	NOUN
bioscience-271	212	4	enter	enter	VERB
bioscience-271	212	5	the	the	DET
bioscience-271	212	6	circulatory	circulatory	ADJ
bioscience-271	212	7	system	system	NOUN
bioscience-271	212	8	,	,	PUNCT
bioscience-271	212	9	they	they	PRON
bioscience-271	212	10	survive	survive	VERB
bioscience-271	212	11	within	within	ADP
bioscience-271	212	12	macrophages	macrophage	NOUN
bioscience-271	212	13	,	,	PUNCT
bioscience-271	212	14	allowing	allow	VERB
bioscience-271	212	15	them	they	PRON
bioscience-271	212	16	to	to	PART
bioscience-271	212	17	evade	evade	VERB
bioscience-271	212	18	the	the	DET
bioscience-271	212	19	immune	immune	ADJ
bioscience-271	212	20	system	system	NOUN
bioscience-271	212	21	and	and	CCONJ
bioscience-271	212	22	spread	spread	VERB
bioscience-271	212	23	to	to	ADP
bioscience-271	212	24	the	the	DET
bioscience-271	212	25	central	central	ADJ
bioscience-271	212	26	nervous	nervous	ADJ
bioscience-271	212	27	system	system	NOUN
bioscience-271	212	28	(	(	PUNCT
bioscience-271	212	29	cns	cns	NOUN
bioscience-271	212	30	)	)	PUNCT
bioscience-271	213	1	[	[	X
bioscience-271	213	2	8	8	NUM
bioscience-271	213	3	;	;	PUNCT
bioscience-271	213	4	44	44	NUM
bioscience-271	213	5	]	]	PUNCT
bioscience-271	213	6	.	.	PUNCT
bioscience-271	214	1	such	such	ADJ
bioscience-271	214	2	macrophages	macrophage	NOUN
bioscience-271	214	3	reportedly	reportedly	ADV
bioscience-271	214	4	act	act	VERB
bioscience-271	214	5	as	as	ADP
bioscience-271	214	6	a	a	DET
bioscience-271	214	7	vehicle	vehicle	NOUN
bioscience-271	214	8	for	for	ADP
bioscience-271	214	9	sa	sa	PROPN
bioscience-271	214	10	,	,	PUNCT
bioscience-271	214	11	allowing	allow	VERB
bioscience-271	214	12	it	it	PRON
bioscience-271	214	13	to	to	PART
bioscience-271	214	14	cross	cross	VERB
bioscience-271	214	15	the	the	DET
bioscience-271	214	16	bbb	bbb	NOUN
bioscience-271	214	17	and	and	CCONJ
bioscience-271	214	18	gain	gain	VERB
bioscience-271	214	19	access	access	NOUN
bioscience-271	214	20	to	to	ADP
bioscience-271	214	21	the	the	DET
bioscience-271	214	22	cns	cns	NOUN
bioscience-271	215	1	[	[	X
bioscience-271	215	2	6	6	NUM
bioscience-271	215	3	;	;	PUNCT
bioscience-271	215	4	8	8	NUM
bioscience-271	215	5	]	]	PUNCT
bioscience-271	215	6	.	.	PUNCT
bioscience-271	216	1	the	the	DET
bioscience-271	216	2	current	current	ADJ
bioscience-271	216	3	investigation	investigation	NOUN
bioscience-271	216	4	revealed	reveal	VERB
bioscience-271	216	5	progressive	progressive	ADJ
bioscience-271	216	6	alterations	alteration	NOUN
bioscience-271	216	7	such	such	ADJ
bioscience-271	216	8	as	as	ADP
bioscience-271	216	9	thickening	thickening	NOUN
bioscience-271	216	10	of	of	ADP
bioscience-271	216	11	the	the	DET
bioscience-271	216	12	meninx	meninx	PROPN
bioscience-271	216	13	primitiva	primitiva	PROPN
bioscience-271	216	14	,	,	PUNCT
bioscience-271	216	15	suggesting	suggest	VERB
bioscience-271	216	16	bacterial	bacterial	ADJ
bioscience-271	216	17	meningitis	meningiti	NOUN
bioscience-271	216	18	similar	similar	ADJ
bioscience-271	216	19	to	to	ADP
bioscience-271	216	20	earlier	early	ADJ
bioscience-271	216	21	studies	study	NOUN
bioscience-271	216	22	[	[	X
bioscience-271	216	23	5	5	NUM
bioscience-271	216	24	;	;	PUNCT
bioscience-271	216	25	6	6	NUM
bioscience-271	216	26	;	;	PUNCT
bioscience-271	216	27	7	7	NUM
bioscience-271	216	28	;	;	PUNCT
bioscience-271	216	29	9	9	NUM
bioscience-271	216	30	]	]	PUNCT
bioscience-271	216	31	.	.	PUNCT
bioscience-271	217	1	regressive	regressive	ADJ
bioscience-271	217	2	changes	change	NOUN
bioscience-271	217	3	in	in	ADP
bioscience-271	217	4	the	the	DET
bioscience-271	217	5	forebrain	forebrain	NOUN
bioscience-271	217	6	,	,	PUNCT
bioscience-271	217	7	midbrain	midbrain	NOUN
bioscience-271	217	8	,	,	PUNCT
bioscience-271	217	9	and	and	CCONJ
bioscience-271	217	10	cerebellum	cerebellum	NOUN
bioscience-271	217	11	of	of	ADP
bioscience-271	217	12	the	the	DET
bioscience-271	217	13	current	current	ADJ
bioscience-271	217	14	study	study	NOUN
bioscience-271	217	15	were	be	AUX
bioscience-271	217	16	in	in	ADP
bioscience-271	217	17	line	line	NOUN
bioscience-271	217	18	with	with	ADP
bioscience-271	217	19	the	the	DET
bioscience-271	217	20	earlier	early	ADJ
bioscience-271	217	21	findings	finding	NOUN
bioscience-271	217	22	.	.	PUNCT
bioscience-271	218	1	they	they	PRON
bioscience-271	218	2	reported	report	VERB
bioscience-271	218	3	that	that	SCONJ
bioscience-271	218	4	bacteria	bacteria	NOUN
bioscience-271	218	5	can	can	AUX
bioscience-271	218	6	permeate	permeate	VERB
bioscience-271	218	7	brain	brain	NOUN
bioscience-271	218	8	parenchymal	parenchymal	ADJ
bioscience-271	218	9	regions	region	NOUN
bioscience-271	218	10	and	and	CCONJ
bioscience-271	218	11	cause	cause	VERB
bioscience-271	218	12	localised	localised	ADJ
bioscience-271	218	13	spongiform	spongiform	NOUN
bioscience-271	218	14	encephalopathy	encephalopathy	ADJ
bioscience-271	218	15	,	,	PUNCT
bioscience-271	218	16	characterised	characterise	VERB
bioscience-271	218	17	by	by	ADP
bioscience-271	218	18	focal	focal	ADJ
bioscience-271	218	19	haemorrhages	haemorrhage	NOUN
bioscience-271	218	20	and	and	CCONJ
bioscience-271	218	21	vacuolization	vacuolization	NOUN
bioscience-271	218	22	,	,	PUNCT
bioscience-271	218	23	mostly	mostly	ADV
bioscience-271	218	24	in	in	ADP
bioscience-271	218	25	the	the	DET
bioscience-271	218	26	midbrain	midbrain	NOUN
bioscience-271	218	27	and	and	CCONJ
bioscience-271	218	28	hindbrain	hindbrain	NOUN
bioscience-271	218	29	.	.	PUNCT
bioscience-271	219	1	also	also	ADV
bioscience-271	219	2	,	,	PUNCT
bioscience-271	219	3	gram	gram	ADJ
bioscience-271	219	4	-	-	PUNCT
bioscience-271	219	5	positive	positive	ADJ
bioscience-271	219	6	cocci	cocci	NOUN
bioscience-271	219	7	in	in	ADP
bioscience-271	219	8	the	the	DET
bioscience-271	219	9	granular	granular	ADJ
bioscience-271	219	10	cell	cell	NOUN
bioscience-271	219	11	layer	layer	NOUN
bioscience-271	219	12	were	be	AUX
bioscience-271	219	13	observed	observe	VERB
bioscience-271	219	14	,	,	PUNCT
bioscience-271	219	15	causing	cause	VERB
bioscience-271	219	16	lysis	lysis	NOUN
bioscience-271	219	17	of	of	ADP
bioscience-271	219	18	granular	granular	ADJ
bioscience-271	219	19	cells	cell	NOUN
bioscience-271	219	20	,	,	PUNCT
bioscience-271	219	21	and	and	CCONJ
bioscience-271	219	22	brain	brain	NOUN
bioscience-271	219	23	lesions	lesion	NOUN
bioscience-271	219	24	,	,	PUNCT
bioscience-271	219	25	includfigure	includfigure	VERB
bioscience-271	219	26	5	5	NUM
bioscience-271	219	27	.	.	PUNCT
bioscience-271	219	28	protein	protein	NOUN
bioscience-271	219	29	–	–	PUNCT
bioscience-271	219	30	ligand	ligand	NOUN
bioscience-271	219	31	interaction	interaction	NOUN
bioscience-271	219	32	of	of	ADP
bioscience-271	219	33	streptococcus	streptococcus	NOUN
bioscience-271	219	34	agalactiae	agalactiae	ADJ
bioscience-271	219	35	virulence	virulence	NOUN
bioscience-271	219	36	factors	factor	NOUN
bioscience-271	219	37	:	:	PUNCT
bioscience-271	220	1	[	[	X
bioscience-271	220	2	a	a	X
bioscience-271	220	3	]	]	X
bioscience-271	220	4	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	220	5	and	and	CCONJ
bioscience-271	220	6	[	[	X
bioscience-271	220	7	b	b	X
bioscience-271	220	8	]	]	X
bioscience-271	220	9	camp	camp	NOUN
bioscience-271	220	10	factor	factor	NOUN
bioscience-271	220	11	against	against	ADP
bioscience-271	220	12	oxolinic	oxolinic	ADJ
bioscience-271	220	13	acid	acid	NOUN
bioscience-271	220	14	,	,	PUNCT
bioscience-271	220	15	visualised	visualise	VERB
bioscience-271	220	16	using	use	VERB
bioscience-271	220	17	the	the	DET
bioscience-271	220	18	pymol	pymol	PROPN
bioscience-271	220	19	tool	tool	NOUN
bioscience-271	220	20	.	.	PUNCT
bioscience-271	221	1	note	note	NOUN
bioscience-271	221	2	:	:	PUNCT
bioscience-271	221	3	green	green	ADJ
bioscience-271	221	4	structures	structure	NOUN
bioscience-271	221	5	represent	represent	VERB
bioscience-271	221	6	ligands	ligand	NOUN
bioscience-271	221	7	;	;	PUNCT
bioscience-271	221	8	coloured	colour	VERB
bioscience-271	221	9	ribbons	ribbon	NOUN
bioscience-271	221	10	depict	depict	VERB
bioscience-271	221	11	the	the	DET
bioscience-271	221	12	target	target	NOUN
bioscience-271	221	13	protein	protein	NOUN
bioscience-271	221	14	;	;	PUNCT
bioscience-271	221	15	yellow	yellow	ADJ
bioscience-271	221	16	dotted	dot	VERB
bioscience-271	221	17	lines	line	NOUN
bioscience-271	221	18	indicate	indicate	VERB
bioscience-271	221	19	interaction	interaction	NOUN
bioscience-271	221	20	sites	site	NOUN
bioscience-271	221	21	.	.	PUNCT
bioscience-271	222	1	distances	distance	NOUN
bioscience-271	222	2	between	between	ADP
bioscience-271	222	3	the	the	DET
bioscience-271	222	4	ligand	ligand	NOUN
bioscience-271	222	5	and	and	CCONJ
bioscience-271	222	6	target	target	VERB
bioscience-271	222	7	at	at	ADP
bioscience-271	222	8	the	the	DET
bioscience-271	222	9	interaction	interaction	NOUN
bioscience-271	222	10	sites	site	NOUN
bioscience-271	222	11	are	be	AUX
bioscience-271	222	12	measured	measure	VERB
bioscience-271	222	13	in	in	ADP
bioscience-271	222	14	angstroms	angstrom	NOUN
bioscience-271	222	15	(	(	PUNCT
bioscience-271	222	16	å	å	NOUN
bioscience-271	222	17	)	)	PUNCT
bioscience-271	222	18	.	.	PUNCT
bioscience-271	223	1	ing	ing	ADJ
bioscience-271	223	2	haemorrhages	haemorrhage	NOUN
bioscience-271	223	3	,	,	PUNCT
bioscience-271	223	4	neuronal	neuronal	ADJ
bioscience-271	223	5	necrosis	necrosis	NOUN
bioscience-271	223	6	,	,	PUNCT
bioscience-271	223	7	and	and	CCONJ
bioscience-271	223	8	inflammation	inflammation	NOUN
bioscience-271	223	9	in	in	ADP
bioscience-271	223	10	regions	region	NOUN
bioscience-271	223	11	governing	govern	VERB
bioscience-271	223	12	swimming	swim	VERB
bioscience-271	223	13	in	in	ADP
bioscience-271	223	14	tilapia	tilapia	NOUN
bioscience-271	223	15	[	[	X
bioscience-271	223	16	9	9	NUM
bioscience-271	223	17	]	]	PUNCT
bioscience-271	223	18	.	.	PUNCT
bioscience-271	224	1	sa	sa	PROPN
bioscience-271	224	2	infection	infection	NOUN
bioscience-271	224	3	also	also	ADV
bioscience-271	224	4	disrupted	disrupt	VERB
bioscience-271	224	5	cerebral	cerebral	ADJ
bioscience-271	224	6	bioenergetics	bioenergetic	NOUN
bioscience-271	224	7	by	by	ADP
bioscience-271	224	8	impairing	impair	VERB
bioscience-271	224	9	mitochondrial	mitochondrial	ADJ
bioscience-271	224	10	complex	complex	NOUN
bioscience-271	224	11	iv	iv	NOUN
bioscience-271	224	12	and	and	CCONJ
bioscience-271	224	13	creatine	creatine	PROPN
bioscience-271	224	14	kinase	kinase	PROPN
bioscience-271	224	15	activities	activity	NOUN
bioscience-271	224	16	,	,	PUNCT
bioscience-271	224	17	leading	lead	VERB
bioscience-271	224	18	to	to	ADP
bioscience-271	224	19	energy	energy	NOUN
bioscience-271	224	20	imbalance	imbalance	NOUN
bioscience-271	224	21	[	[	X
bioscience-271	224	22	45	45	NUM
bioscience-271	224	23	]	]	PUNCT
bioscience-271	224	24	.	.	PUNCT
bioscience-271	225	1	all	all	DET
bioscience-271	225	2	these	these	DET
bioscience-271	225	3	investigations	investigation	NOUN
bioscience-271	225	4	pointed	point	VERB
bioscience-271	225	5	out	out	ADP
bioscience-271	225	6	that	that	SCONJ
bioscience-271	225	7	sa	sa	PROPN
bioscience-271	225	8	is	be	AUX
bioscience-271	225	9	neurotropic	neurotropic	ADJ
bioscience-271	225	10	,	,	PUNCT
bioscience-271	225	11	seriously	seriously	ADV
bioscience-271	225	12	harming	harm	VERB
bioscience-271	225	13	neurological	neurological	ADJ
bioscience-271	225	14	function	function	NOUN
bioscience-271	225	15	and	and	CCONJ
bioscience-271	225	16	influencing	influence	VERB
bioscience-271	225	17	swimming	swimming	NOUN
bioscience-271	225	18	behaviour	behaviour	NOUN
bioscience-271	225	19	and	and	CCONJ
bioscience-271	225	20	survival	survival	NOUN
bioscience-271	225	21	of	of	ADP
bioscience-271	225	22	fish	fish	NOUN
bioscience-271	225	23	.	.	PUNCT
bioscience-271	226	1	the	the	DET
bioscience-271	226	2	inflammatory	inflammatory	ADJ
bioscience-271	226	3	responses	response	NOUN
bioscience-271	226	4	in	in	ADP
bioscience-271	226	5	the	the	DET
bioscience-271	226	6	forebrain	forebrain	NOUN
bioscience-271	226	7	and	and	CCONJ
bioscience-271	226	8	mid	mid	NOUN
bioscience-271	226	9	-	-	NOUN
bioscience-271	226	10	brain	brain	NOUN
bioscience-271	226	11	of	of	ADP
bioscience-271	226	12	sa	sa	NOUN
bioscience-271	226	13	-	-	PUNCT
bioscience-271	226	14	infected	infect	VERB
bioscience-271	226	15	tilapias	tilapia	NOUN
bioscience-271	226	16	corroborated	corroborate	VERB
bioscience-271	226	17	earlier	early	ADJ
bioscience-271	226	18	studies	study	NOUN
bioscience-271	226	19	[	[	X
bioscience-271	226	20	6	6	NUM
bioscience-271	226	21	;	;	PUNCT
bioscience-271	226	22	7	7	NUM
bioscience-271	226	23	;	;	PUNCT
bioscience-271	226	24	8	8	NUM
bioscience-271	226	25	;	;	PUNCT
bioscience-271	226	26	9	9	NUM
bioscience-271	226	27	;	;	PUNCT
bioscience-271	226	28	46	46	NUM
bioscience-271	226	29	]	]	PUNCT
bioscience-271	226	30	,	,	PUNCT
bioscience-271	226	31	which	which	PRON
bioscience-271	226	32	documented	document	VERB
bioscience-271	226	33	meningitis	meningitis	NOUN
bioscience-271	226	34	and	and	CCONJ
bioscience-271	226	35	several	several	ADJ
bioscience-271	226	36	significant	significant	ADJ
bioscience-271	226	37	brain	brain	NOUN
bioscience-271	226	38	alterations	alteration	NOUN
bioscience-271	226	39	.	.	PUNCT
bioscience-271	227	1	sa	sa	PROPN
bioscience-271	227	2	reportedly	reportedly	ADV
bioscience-271	227	3	triggers	trigger	VERB
bioscience-271	227	4	an	an	DET
bioscience-271	227	5	inflammatory	inflammatory	ADJ
bioscience-271	227	6	response	response	NOUN
bioscience-271	227	7	,	,	PUNCT
bioscience-271	227	8	which	which	PRON
bioscience-271	227	9	impairs	impair	VERB
bioscience-271	227	10	phagocytosis	phagocytosis	NOUN
bioscience-271	227	11	,	,	PUNCT
bioscience-271	227	12	cytokine	cytokine	ADJ
bioscience-271	227	13	and	and	CCONJ
bioscience-271	227	14	chemokine	chemokine	ADJ
bioscience-271	227	15	levels	level	NOUN
bioscience-271	227	16	,	,	PUNCT
bioscience-271	227	17	contributing	contribute	VERB
bioscience-271	227	18	to	to	PART
bioscience-271	227	19	oxidative	oxidative	ADJ
bioscience-271	227	20	stress	stress	NOUN
bioscience-271	227	21	and	and	CCONJ
bioscience-271	227	22	disruption	disruption	NOUN
bioscience-271	227	23	of	of	ADP
bioscience-271	227	24	the	the	DET
bioscience-271	227	25	bbb	bbb	NOUN
bioscience-271	228	1	[	[	X
bioscience-271	228	2	45	45	NUM
bioscience-271	228	3	;	;	PUNCT
bioscience-271	228	4	47	47	NUM
bioscience-271	228	5	]	]	PUNCT
bioscience-271	228	6	and	and	CCONJ
bioscience-271	228	7	interfering	interfere	VERB
bioscience-271	228	8	with	with	ADP
bioscience-271	228	9	the	the	DET
bioscience-271	228	10	immune	immune	ADJ
bioscience-271	228	11	system	system	NOUN
bioscience-271	228	12	[	[	X
bioscience-271	228	13	48	48	NUM
bioscience-271	228	14	]	]	PUNCT
bioscience-271	228	15	.	.	PUNCT
bioscience-271	229	1	the	the	DET
bioscience-271	229	2	resulting	result	VERB
bioscience-271	229	3	neuroinflammation	neuroinflammation	NOUN
bioscience-271	229	4	can	can	AUX
bioscience-271	229	5	be	be	AUX
bioscience-271	229	6	characterized	characterize	VERB
bioscience-271	229	7	by	by	ADP
bioscience-271	229	8	immune	immune	ADJ
bioscience-271	229	9	cell	cell	NOUN
bioscience-271	229	10	migration	migration	NOUN
bioscience-271	229	11	and	and	CCONJ
bioscience-271	229	12	the	the	DET
bioscience-271	229	13	production	production	NOUN
bioscience-271	229	14	of	of	ADP
bioscience-271	229	15	pro	pro	ADJ
bioscience-271	229	16	-	-	ADJ
bioscience-271	229	17	inflammatory	inflammatory	ADJ
bioscience-271	229	18	cytokines	cytokine	NOUN
bioscience-271	229	19	,	,	PUNCT
bioscience-271	229	20	which	which	PRON
bioscience-271	229	21	drive	drive	VERB
bioscience-271	229	22	the	the	DET
bioscience-271	229	23	immune	immune	ADJ
bioscience-271	229	24	response	response	NOUN
bioscience-271	229	25	[	[	X
bioscience-271	229	26	6	6	NUM
bioscience-271	229	27	]	]	PUNCT
bioscience-271	229	28	.	.	PUNCT
bioscience-271	230	1	antibiotics	antibiotic	NOUN
bioscience-271	230	2	like	like	ADP
bioscience-271	230	3	ampicillin	ampicillin	PROPN
bioscience-271	230	4	,	,	PUNCT
bioscience-271	230	5	colistin	colistin	PROPN
bioscience-271	230	6	sulfate	sulfate	PROPN
bioscience-271	230	7	,	,	PUNCT
bioscience-271	230	8	sulfadimethoxineormetoprim	sulfadimethoxineormetoprim	NOUN
bioscience-271	230	9	,	,	PUNCT
bioscience-271	230	10	and	and	CCONJ
bioscience-271	230	11	florfenicol	florfenicol	NOUN
bioscience-271	230	12	are	be	AUX
bioscience-271	230	13	effectively	effectively	ADV
bioscience-271	230	14	used	use	VERB
bioscience-271	230	15	against	against	ADP
bioscience-271	230	16	streptococcus	streptococcus	NOUN
bioscience-271	230	17	spp	spp	NOUN
bioscience-271	230	18	.	.	PUNCT
bioscience-271	231	1	moreover	moreover	ADV
bioscience-271	231	2	,	,	PUNCT
bioscience-271	231	3	the	the	DET
bioscience-271	231	4	use	use	NOUN
bioscience-271	231	5	of	of	ADP
bioscience-271	231	6	β	β	NOUN
bioscience-271	231	7	-	-	NOUN
bioscience-271	231	8	lactams	lactam	NOUN
bioscience-271	231	9	,	,	PUNCT
bioscience-271	231	10	fluoroquinolones	fluoroquinolone	NOUN
bioscience-271	231	11	and	and	CCONJ
bioscience-271	231	12	macrolides	macrolide	NOUN
bioscience-271	231	13	has	have	AUX
bioscience-271	231	14	been	be	AUX
bioscience-271	231	15	highlighted	highlight	VERB
bioscience-271	231	16	as	as	ADP
bioscience-271	231	17	effective	effective	ADJ
bioscience-271	231	18	against	against	ADP
bioscience-271	231	19	meningitiscausing	meningitiscause	VERB
bioscience-271	231	20	s.	s.	PROPN
bioscience-271	231	21	pneumoniae	pneumoniae	ADP
bioscience-271	231	22	[	[	X
bioscience-271	231	23	49	49	NUM
bioscience-271	231	24	;	;	PUNCT
bioscience-271	231	25	50	50	NUM
bioscience-271	231	26	;	;	PUNCT
bioscience-271	231	27	51	51	NUM
bioscience-271	231	28	;	;	PUNCT
bioscience-271	231	29	46	46	NUM
bioscience-271	231	30	;	;	PUNCT
bioscience-271	231	31	52	52	NUM
bioscience-271	231	32	]	]	PUNCT
bioscience-271	231	33	.	.	PUNCT
bioscience-271	232	1	in	in	ADP
bioscience-271	232	2	this	this	DET
bioscience-271	232	3	study	study	NOUN
bioscience-271	232	4	,	,	PUNCT
bioscience-271	232	5	the	the	DET
bioscience-271	232	6	ri	ri	PROPN
bioscience-271	232	7	values	value	NOUN
bioscience-271	232	8	increased	increase	VERB
bioscience-271	232	9	during	during	ADP
bioscience-271	232	10	the	the	DET
bioscience-271	232	11	initial	initial	ADJ
bioscience-271	232	12	period	period	NOUN
bioscience-271	232	13	of	of	ADP
bioscience-271	232	14	infection	infection	NOUN
bioscience-271	232	15	and	and	CCONJ
bioscience-271	232	16	highlights	highlight	NOUN
bioscience-271	232	17	in	in	ADP
bioscience-271	232	18	bioscience	bioscience	NOUN
bioscience-271	232	19	page	page	NOUN
bioscience-271	232	20	6	6	NUM
bioscience-271	232	21	of	of	ADP
bioscience-271	232	22	10	10	NUM
bioscience-271	232	23	october	october	PROPN
bioscience-271	232	24	2025|volume	2025|volume	NUM
bioscience-271	232	25	8	8	NUM
bioscience-271	232	26	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	232	27	sinha	sinha	PROPN
bioscience-271	232	28	p	p	PROPN
bioscience-271	232	29	et	et	PROPN
bioscience-271	232	30	al	al	PROPN
bioscience-271	232	31	.	.	PROPN
bioscience-271	232	32	,	,	PUNCT
bioscience-271	232	33	2025	2025	NUM
bioscience-271	232	34	effect	effect	NOUN
bioscience-271	232	35	of	of	ADP
bioscience-271	232	36	oxolinic	oxolinic	ADJ
bioscience-271	232	37	acid	acid	NOUN
bioscience-271	232	38	therapy	therapy	NOUN
bioscience-271	232	39	table	table	NOUN
bioscience-271	232	40	3	3	NUM
bioscience-271	232	41	.	.	X
bioscience-271	232	42	molecular	molecular	ADJ
bioscience-271	232	43	docking	docking	NOUN
bioscience-271	232	44	summary	summary	NOUN
bioscience-271	232	45	of	of	ADP
bioscience-271	232	46	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	232	47	aam99596	aam99596	NOUN
bioscience-271	232	48	and	and	CCONJ
bioscience-271	232	49	camp	camp	NOUN
bioscience-271	232	50	factor	factor	NOUN
bioscience-271	232	51	aki96324	aki96324	NOUN
bioscience-271	232	52	of	of	ADP
bioscience-271	232	53	streptococcus	streptococcus	ADJ
bioscience-271	232	54	agalactiae	agalactiae	NOUN
bioscience-271	232	55	against	against	ADP
bioscience-271	232	56	the	the	DET
bioscience-271	232	57	ligand	ligand	ADJ
bioscience-271	232	58	oxolinic	oxolinic	ADJ
bioscience-271	232	59	acid	acid	PROPN
bioscience-271	232	60	using	use	VERB
bioscience-271	232	61	the	the	DET
bioscience-271	232	62	autodock	autodock	NOUN
bioscience-271	232	63	tool	tool	NOUN
bioscience-271	232	64	.	.	PUNCT
bioscience-271	233	1	proteins	protein	NOUN
bioscience-271	233	2	affinity	affinity	NOUN
bioscience-271	233	3	ligand	ligand	NOUN
bioscience-271	233	4	–	–	PUNCT
bioscience-271	233	5	protein	protein	NOUN
bioscience-271	233	6	interaction	interaction	NOUN
bioscience-271	233	7	distance	distance	NOUN
bioscience-271	233	8	(	(	PUNCT
bioscience-271	233	9	å	å	NOUN
bioscience-271	233	10	)	)	PUNCT
bioscience-271	233	11	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	233	12	-4.99	-4.99	NUM
bioscience-271	233	13	a	a	PRON
bioscience-271	233	14	:	:	PUNCT
bioscience-271	233	15	asn1̀97	asn1̀97	NUM
bioscience-271	233	16	:	:	PUNCT
bioscience-271	233	17	od1–:unl1̀:h	od1–:unl1̀:h	NOUN
bioscience-271	233	18	2.3	2.3	NUM
bioscience-271	233	19	a	a	DET
bioscience-271	233	20	:	:	PUNCT
bioscience-271	233	21	lys1̀93	lys1̀93	NOUN
bioscience-271	233	22	:	:	PUNCT
bioscience-271	233	23	nz–:unl1̀:o	nz–:unl1̀:o	PROPN
bioscience-271	233	24	2.7	2.7	NUM
bioscience-271	233	25	a	a	PRON
bioscience-271	233	26	:	:	PUNCT
bioscience-271	233	27	asn1̀97	asn1̀97	NUM
bioscience-271	233	28	:	:	PUNCT
bioscience-271	233	29	od1–:unl1̀:o	od1–:unl1̀:o	ADP
bioscience-271	233	30	3.0	3.0	NUM
bioscience-271	233	31	a	a	DET
bioscience-271	233	32	:	:	PUNCT
bioscience-271	233	33	lys1̀93	lys1̀93	NOUN
bioscience-271	233	34	:	:	PUNCT
bioscience-271	233	35	nz–:unl1̀:o	nz–:unl1̀:o	ADJ
bioscience-271	233	36	3.2	3.2	NUM
bioscience-271	233	37	camp	camp	NOUN
bioscience-271	233	38	factor	factor	NOUN
bioscience-271	233	39	-4.31	-4.31	ADP
bioscience-271	233	40	a	a	PRON
bioscience-271	233	41	:	:	PUNCT
bioscience-271	233	42	lys2̀05	lys2̀05	ADJ
bioscience-271	233	43	:	:	PUNCT
bioscience-271	233	44	nz–:unl1̀:o	nz–:unl1̀:o	PROPN
bioscience-271	233	45	2.9	2.9	NUM
bioscience-271	233	46	a	a	PRON
bioscience-271	233	47	:	:	PUNCT
bioscience-271	233	48	arg2̀04	arg2̀04	ADJ
bioscience-271	233	49	:	:	PUNCT
bioscience-271	233	50	n–:unl1̀:o	n–:unl1̀:o	NUM
bioscience-271	233	51	3.1	3.1	NUM
bioscience-271	234	1	a	a	DET
bioscience-271	234	2	:	:	PUNCT
bioscience-271	234	3	arg2̀04	arg2̀04	ADJ
bioscience-271	234	4	:	:	PUNCT
bioscience-271	234	5	nh1–:unl1̀:o	nh1–:unl1̀:o	ADV
bioscience-271	234	6	3.2	3.2	NUM
bioscience-271	234	7	gradually	gradually	ADV
bioscience-271	234	8	reduced	reduce	VERB
bioscience-271	234	9	with	with	ADP
bioscience-271	234	10	time	time	NOUN
bioscience-271	234	11	,	,	PUNCT
bioscience-271	234	12	indicating	indicate	VERB
bioscience-271	234	13	the	the	DET
bioscience-271	234	14	fish	fish	NOUN
bioscience-271	234	15	’s	’s	PART
bioscience-271	234	16	adaptive	adaptive	ADJ
bioscience-271	234	17	and	and	CCONJ
bioscience-271	234	18	immune	immune	ADJ
bioscience-271	234	19	responses	response	NOUN
bioscience-271	234	20	to	to	ADP
bioscience-271	234	21	healing	heal	VERB
bioscience-271	234	22	the	the	DET
bioscience-271	234	23	brain	brain	NOUN
bioscience-271	234	24	lesions	lesion	NOUN
bioscience-271	234	25	.	.	PUNCT
bioscience-271	235	1	while	while	SCONJ
bioscience-271	235	2	the	the	DET
bioscience-271	235	3	effects	effect	NOUN
bioscience-271	235	4	were	be	AUX
bioscience-271	235	5	almost	almost	ADV
bioscience-271	235	6	similar	similar	ADJ
bioscience-271	235	7	,	,	PUNCT
bioscience-271	235	8	the	the	DET
bioscience-271	235	9	oa	oa	ADV
bioscience-271	235	10	-	-	PUNCT
bioscience-271	235	11	treated	treat	VERB
bioscience-271	235	12	tilapia	tilapia	NOUN
bioscience-271	235	13	showed	show	VERB
bioscience-271	235	14	lower	low	ADJ
bioscience-271	235	15	ri	ri	NOUN
bioscience-271	235	16	.	.	PUNCT
bioscience-271	236	1	the	the	PRON
bioscience-271	236	2	oa	oa	NOUN
bioscience-271	236	3	-	-	PUNCT
bioscience-271	236	4	treatment	treatment	NOUN
bioscience-271	236	5	facilitated	facilitate	VERB
bioscience-271	236	6	quicker	quick	ADJ
bioscience-271	236	7	recovery	recovery	NOUN
bioscience-271	236	8	,	,	PUNCT
bioscience-271	236	9	indicating	indicate	VERB
bioscience-271	236	10	that	that	SCONJ
bioscience-271	236	11	oa	oa	PROPN
bioscience-271	236	12	can	can	AUX
bioscience-271	236	13	cross	cross	VERB
bioscience-271	236	14	the	the	DET
bioscience-271	236	15	bbb	bbb	NOUN
bioscience-271	236	16	and	and	CCONJ
bioscience-271	236	17	lessen	lessen	VERB
bioscience-271	236	18	the	the	DET
bioscience-271	236	19	sa	sa	NOUN
bioscience-271	236	20	-	-	PUNCT
bioscience-271	236	21	infection	infection	NOUN
bioscience-271	236	22	.	.	PUNCT
bioscience-271	237	1	the	the	DET
bioscience-271	237	2	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	237	3	and	and	CCONJ
bioscience-271	237	4	the	the	DET
bioscience-271	237	5	camp	camp	NOUN
bioscience-271	237	6	factor	factor	NOUN
bioscience-271	237	7	play	play	VERB
bioscience-271	237	8	crucial	crucial	ADJ
bioscience-271	237	9	roles	role	NOUN
bioscience-271	237	10	in	in	ADP
bioscience-271	237	11	the	the	DET
bioscience-271	237	12	pathogenesis	pathogenesis	NOUN
bioscience-271	237	13	of	of	ADP
bioscience-271	237	14	sa	sa	PROPN
bioscience-271	237	15	.	.	PUNCT
bioscience-271	238	1	the	the	DET
bioscience-271	238	2	infection	infection	NOUN
bioscience-271	238	3	may	may	AUX
bioscience-271	238	4	influence	influence	VERB
bioscience-271	238	5	bacterial	bacterial	ADJ
bioscience-271	238	6	interactions	interaction	NOUN
bioscience-271	238	7	with	with	ADP
bioscience-271	238	8	the	the	DET
bioscience-271	238	9	host	host	NOUN
bioscience-271	238	10	,	,	PUNCT
bioscience-271	238	11	create	create	VERB
bioscience-271	238	12	specific	specific	ADJ
bioscience-271	238	13	pores	pore	NOUN
bioscience-271	238	14	in	in	ADP
bioscience-271	238	15	host	host	NOUN
bioscience-271	238	16	membranes	membrane	NOUN
bioscience-271	238	17	,	,	PUNCT
bioscience-271	238	18	modify	modify	VERB
bioscience-271	238	19	proteins	protein	NOUN
bioscience-271	238	20	and	and	CCONJ
bioscience-271	238	21	carbohydrates	carbohydrate	NOUN
bioscience-271	238	22	,	,	PUNCT
bioscience-271	238	23	and	and	CCONJ
bioscience-271	238	24	disrupt	disrupt	VERB
bioscience-271	238	25	cell	cell	NOUN
bioscience-271	238	26	integrity	integrity	NOUN
bioscience-271	238	27	,	,	PUNCT
bioscience-271	238	28	leading	lead	VERB
bioscience-271	238	29	to	to	ADP
bioscience-271	238	30	cell	cell	NOUN
bioscience-271	238	31	lysis	lysis	NOUN
bioscience-271	238	32	[	[	X
bioscience-271	238	33	24	24	NUM
bioscience-271	238	34	;	;	PUNCT
bioscience-271	238	35	53	53	NUM
bioscience-271	238	36	]	]	PUNCT
bioscience-271	238	37	.	.	PUNCT
bioscience-271	239	1	the	the	DET
bioscience-271	239	2	lesser	less	ADJ
bioscience-271	239	3	impact	impact	NOUN
bioscience-271	239	4	of	of	ADP
bioscience-271	239	5	sa	sa	NOUN
bioscience-271	239	6	-	-	PUNCT
bioscience-271	239	7	infection	infection	NOUN
bioscience-271	239	8	in	in	ADP
bioscience-271	239	9	the	the	DET
bioscience-271	239	10	brain	brain	NOUN
bioscience-271	239	11	suggested	suggest	VERB
bioscience-271	239	12	that	that	SCONJ
bioscience-271	239	13	the	the	DET
bioscience-271	239	14	oa	oa	PROPN
bioscience-271	239	15	can	can	AUX
bioscience-271	239	16	exhibit	exhibit	VERB
bioscience-271	239	17	binding	bind	VERB
bioscience-271	239	18	affinities	affinity	NOUN
bioscience-271	239	19	with	with	ADP
bioscience-271	239	20	virulent	virulent	ADJ
bioscience-271	239	21	proteins	protein	NOUN
bioscience-271	239	22	,	,	PUNCT
bioscience-271	239	23	as	as	SCONJ
bioscience-271	239	24	confirmed	confirm	VERB
bioscience-271	239	25	by	by	ADP
bioscience-271	239	26	interactions	interaction	NOUN
bioscience-271	239	27	with	with	ADP
bioscience-271	239	28	glycosyltransferases	glycosyltransferase	NOUN
bioscience-271	239	29	and	and	CCONJ
bioscience-271	239	30	the	the	DET
bioscience-271	239	31	camp	camp	NOUN
bioscience-271	239	32	factor	factor	NOUN
bioscience-271	239	33	,	,	PUNCT
bioscience-271	239	34	and	and	CCONJ
bioscience-271	239	35	to	to	PART
bioscience-271	239	36	prevent	prevent	VERB
bioscience-271	239	37	the	the	DET
bioscience-271	239	38	activities	activity	NOUN
bioscience-271	239	39	of	of	ADP
bioscience-271	239	40	sa	sa	PROPN
bioscience-271	239	41	.	.	PUNCT
bioscience-271	240	1	in	in	ADP
bioscience-271	240	2	the	the	DET
bioscience-271	240	3	molecular	molecular	ADJ
bioscience-271	240	4	docking	docking	NOUN
bioscience-271	240	5	study	study	NOUN
bioscience-271	240	6	,	,	PUNCT
bioscience-271	240	7	our	our	PRON
bioscience-271	240	8	observations	observation	NOUN
bioscience-271	240	9	on	on	ADP
bioscience-271	240	10	the	the	DET
bioscience-271	240	11	shorter	short	ADJ
bioscience-271	240	12	bond	bond	NOUN
bioscience-271	240	13	distances	distance	NOUN
bioscience-271	240	14	and	and	CCONJ
bioscience-271	240	15	number	number	NOUN
bioscience-271	240	16	of	of	ADP
bioscience-271	240	17	interactions	interaction	NOUN
bioscience-271	240	18	with	with	ADP
bioscience-271	240	19	multiple	multiple	ADJ
bioscience-271	240	20	hydrogen	hydrogen	NOUN
bioscience-271	240	21	bonds	bond	NOUN
bioscience-271	240	22	and	and	CCONJ
bioscience-271	240	23	close	close	ADJ
bioscience-271	240	24	-	-	PUNCT
bioscience-271	240	25	contact	contact	NOUN
bioscience-271	240	26	residues	residue	NOUN
bioscience-271	240	27	suggested	suggest	VERB
bioscience-271	240	28	stable	stable	ADJ
bioscience-271	240	29	and	and	CCONJ
bioscience-271	240	30	favourable	favourable	ADJ
bioscience-271	240	31	binding	binding	ADJ
bioscience-271	240	32	conformations	conformation	NOUN
bioscience-271	240	33	.	.	PUNCT
bioscience-271	241	1	these	these	DET
bioscience-271	241	2	results	result	NOUN
bioscience-271	241	3	supported	support	VERB
bioscience-271	241	4	the	the	DET
bioscience-271	241	5	potential	potential	NOUN
bioscience-271	241	6	of	of	ADP
bioscience-271	241	7	oa	oa	PRON
bioscience-271	241	8	as	as	ADP
bioscience-271	241	9	a	a	DET
bioscience-271	241	10	strong	strong	ADJ
bioscience-271	241	11	inhibitor	inhibitor	NOUN
bioscience-271	241	12	of	of	ADP
bioscience-271	241	13	the	the	DET
bioscience-271	241	14	virulent	virulent	ADJ
bioscience-271	241	15	proteins	protein	NOUN
bioscience-271	241	16	of	of	ADP
bioscience-271	241	17	sa	sa	NOUN
bioscience-271	241	18	.	.	PUNCT
bioscience-271	242	1	our	our	PRON
bioscience-271	242	2	study	study	NOUN
bioscience-271	242	3	further	far	ADV
bioscience-271	242	4	noted	note	VERB
bioscience-271	242	5	an	an	DET
bioscience-271	242	6	insignificant	insignificant	ADJ
bioscience-271	242	7	difference	difference	NOUN
bioscience-271	242	8	in	in	ADP
bioscience-271	242	9	mortalities	mortality	NOUN
bioscience-271	242	10	due	due	ADP
bioscience-271	242	11	to	to	ADP
bioscience-271	242	12	the	the	DET
bioscience-271	242	13	tested	test	VERB
bioscience-271	242	14	strains	strain	NOUN
bioscience-271	242	15	moderately	moderately	ADV
bioscience-271	242	16	high	high	ADJ
bioscience-271	242	17	mic	mic	NOUN
bioscience-271	242	18	for	for	ADP
bioscience-271	242	19	oa	oa	NOUN
bioscience-271	242	20	.	.	PUNCT
bioscience-271	243	1	strikingly	strikingly	ADV
bioscience-271	243	2	,	,	PUNCT
bioscience-271	243	3	the	the	DET
bioscience-271	243	4	7	7	NUM
bioscience-271	243	5	days	day	NOUN
bioscience-271	243	6	of	of	ADP
bioscience-271	243	7	treatment	treatment	NOUN
bioscience-271	243	8	at	at	ADP
bioscience-271	243	9	12	12	NUM
bioscience-271	243	10	mg	mg	NOUN
bioscience-271	243	11	oa	oa	PROPN
bioscience-271	243	12	/	/	SYM
bioscience-271	243	13	kg	kg	NOUN
bioscience-271	243	14	fish	fish	NOUN
bioscience-271	243	15	/	/	SYM
bioscience-271	243	16	day	day	NOUN
bioscience-271	243	17	inhibited	inhibit	VERB
bioscience-271	243	18	the	the	DET
bioscience-271	243	19	sa	sa	PROPN
bioscience-271	243	20	strain	strain	NOUN
bioscience-271	243	21	,	,	PUNCT
bioscience-271	243	22	mitigated	mitigate	VERB
bioscience-271	243	23	the	the	DET
bioscience-271	243	24	severity	severity	NOUN
bioscience-271	243	25	of	of	ADP
bioscience-271	243	26	brain	brain	NOUN
bioscience-271	243	27	damage	damage	NOUN
bioscience-271	243	28	,	,	PUNCT
bioscience-271	243	29	and	and	CCONJ
bioscience-271	243	30	improved	improve	VERB
bioscience-271	243	31	fish	fish	NOUN
bioscience-271	243	32	survival	survival	NOUN
bioscience-271	243	33	.	.	PUNCT
bioscience-271	244	1	thus	thus	ADV
bioscience-271	244	2	,	,	PUNCT
bioscience-271	244	3	these	these	DET
bioscience-271	244	4	biologically	biologically	ADV
bioscience-271	244	5	meaningful	meaningful	ADJ
bioscience-271	244	6	results	result	NOUN
bioscience-271	244	7	proved	prove	VERB
bioscience-271	244	8	the	the	DET
bioscience-271	244	9	protective	protective	ADJ
bioscience-271	244	10	effect	effect	NOUN
bioscience-271	244	11	of	of	ADP
bioscience-271	244	12	oa	oa	PRON
bioscience-271	244	13	against	against	ADP
bioscience-271	244	14	the	the	DET
bioscience-271	244	15	progression	progression	NOUN
bioscience-271	244	16	of	of	ADP
bioscience-271	244	17	sa	sa	NOUN
bioscience-271	244	18	-	-	PUNCT
bioscience-271	244	19	infection	infection	NOUN
bioscience-271	244	20	and	and	CCONJ
bioscience-271	244	21	ensuing	ensue	VERB
bioscience-271	244	22	brain	brain	NOUN
bioscience-271	244	23	histopathological	histopathological	ADJ
bioscience-271	244	24	changes	change	NOUN
bioscience-271	244	25	.	.	PUNCT
bioscience-271	245	1	however	however	ADV
bioscience-271	245	2	,	,	PUNCT
bioscience-271	245	3	future	future	ADJ
bioscience-271	245	4	studies	study	NOUN
bioscience-271	245	5	are	be	AUX
bioscience-271	245	6	warranted	warrant	VERB
bioscience-271	245	7	on	on	ADP
bioscience-271	245	8	the	the	DET
bioscience-271	245	9	expression	expression	NOUN
bioscience-271	245	10	of	of	ADP
bioscience-271	245	11	glycosyltransferase	glycosyltransferase	NOUN
bioscience-271	245	12	,	,	PUNCT
bioscience-271	245	13	camp	camp	NOUN
bioscience-271	245	14	factor	factor	NOUN
bioscience-271	245	15	and	and	CCONJ
bioscience-271	245	16	other	other	ADJ
bioscience-271	245	17	virulence	virulence	NOUN
bioscience-271	245	18	factors	factor	NOUN
bioscience-271	245	19	using	use	VERB
bioscience-271	245	20	qrt	qrt	NOUN
bioscience-271	245	21	-	-	PUNCT
bioscience-271	245	22	pcr	pcr	ADJ
bioscience-271	245	23	or	or	CCONJ
bioscience-271	245	24	western	western	ADJ
bioscience-271	245	25	blotting	blotting	NOUN
bioscience-271	245	26	to	to	PART
bioscience-271	245	27	provide	provide	VERB
bioscience-271	245	28	direct	direct	ADJ
bioscience-271	245	29	evidence	evidence	NOUN
bioscience-271	245	30	of	of	ADP
bioscience-271	245	31	their	their	PRON
bioscience-271	245	32	involvement	involvement	NOUN
bioscience-271	245	33	in	in	ADP
bioscience-271	245	34	sa	sa	NOUN
bioscience-271	245	35	pathogenesis	pathogenesis	NOUN
bioscience-271	245	36	and	and	CCONJ
bioscience-271	245	37	oas	oas	PROPN
bioscience-271	245	38	mechanism	mechanism	NOUN
bioscience-271	245	39	of	of	ADP
bioscience-271	245	40	action	action	NOUN
bioscience-271	245	41	.	.	PUNCT
bioscience-271	246	1	conclusions	conclusion	NOUN
bioscience-271	246	2	our	our	PRON
bioscience-271	246	3	results	result	NOUN
bioscience-271	246	4	demonstrated	demonstrate	VERB
bioscience-271	246	5	that	that	SCONJ
bioscience-271	246	6	understanding	understand	VERB
bioscience-271	246	7	the	the	DET
bioscience-271	246	8	role	role	NOUN
bioscience-271	246	9	of	of	ADP
bioscience-271	246	10	virulence	virulence	NOUN
bioscience-271	246	11	proteins	protein	NOUN
bioscience-271	246	12	of	of	ADP
bioscience-271	246	13	s.	s.	PROPN
bioscience-271	246	14	agalactiae	agalactiae	PROPN
bioscience-271	246	15	in	in	ADP
bioscience-271	246	16	pathogenesis	pathogenesis	NOUN
bioscience-271	246	17	and	and	CCONJ
bioscience-271	246	18	interactions	interaction	NOUN
bioscience-271	246	19	with	with	ADP
bioscience-271	246	20	drugs	drug	NOUN
bioscience-271	246	21	can	can	AUX
bioscience-271	246	22	offer	offer	VERB
bioscience-271	246	23	scope	scope	NOUN
bioscience-271	246	24	for	for	ADP
bioscience-271	246	25	new	new	ADJ
bioscience-271	246	26	therapeutic	therapeutic	ADJ
bioscience-271	246	27	strategies	strategy	NOUN
bioscience-271	246	28	,	,	PUNCT
bioscience-271	246	29	such	such	ADJ
bioscience-271	246	30	as	as	ADP
bioscience-271	246	31	targeting	target	VERB
bioscience-271	246	32	such	such	ADJ
bioscience-271	246	33	factors	factor	NOUN
bioscience-271	246	34	or	or	CCONJ
bioscience-271	246	35	blocking	block	VERB
bioscience-271	246	36	interactions	interaction	NOUN
bioscience-271	246	37	with	with	ADP
bioscience-271	246	38	host	host	NOUN
bioscience-271	246	39	cells	cell	NOUN
bioscience-271	246	40	and	and	CCONJ
bioscience-271	246	41	developing	develop	VERB
bioscience-271	246	42	targeted	targeted	ADJ
bioscience-271	246	43	therapies	therapy	NOUN
bioscience-271	246	44	that	that	PRON
bioscience-271	246	45	can	can	AUX
bioscience-271	246	46	disrupt	disrupt	VERB
bioscience-271	246	47	the	the	DET
bioscience-271	246	48	bacterial	bacterial	ADJ
bioscience-271	246	49	toxin	toxin	NOUN
bioscience-271	246	50	’s	’s	PART
bioscience-271	246	51	activity	activity	NOUN
bioscience-271	246	52	.	.	PUNCT
bioscience-271	247	1	in	in	ADP
bioscience-271	247	2	this	this	DET
bioscience-271	247	3	study	study	NOUN
bioscience-271	247	4	,	,	PUNCT
bioscience-271	247	5	oxolinic	oxolinic	ADJ
bioscience-271	247	6	acid	acid	NOUN
bioscience-271	247	7	(	(	PUNCT
bioscience-271	247	8	oa	oa	NOUN
bioscience-271	247	9	)	)	PUNCT
bioscience-271	247	10	therapy	therapy	NOUN
bioscience-271	247	11	in	in	ADP
bioscience-271	247	12	s.	s.	PROPN
bioscience-271	247	13	agalactiae	agalactiae	PROPN
bioscience-271	247	14	-	-	PUNCT
bioscience-271	247	15	infected	infect	VERB
bioscience-271	247	16	tilapia	tilapia	NOUN
bioscience-271	247	17	revealed	reveal	VERB
bioscience-271	247	18	a	a	DET
bioscience-271	247	19	protective	protective	ADJ
bioscience-271	247	20	effect	effect	NOUN
bioscience-271	247	21	by	by	ADP
bioscience-271	247	22	reducing	reduce	VERB
bioscience-271	247	23	the	the	DET
bioscience-271	247	24	mortalities	mortality	NOUN
bioscience-271	247	25	,	,	PUNCT
bioscience-271	247	26	brain	brain	NOUN
bioscience-271	247	27	damage	damage	NOUN
bioscience-271	247	28	and	and	CCONJ
bioscience-271	247	29	histopathological	histopathological	ADJ
bioscience-271	247	30	alterations	alteration	NOUN
bioscience-271	247	31	.	.	PUNCT
bioscience-271	248	1	the	the	DET
bioscience-271	248	2	treated	treat	VERB
bioscience-271	248	3	fish	fish	NOUN
bioscience-271	248	4	unveiled	unveil	VERB
bioscience-271	248	5	less	less	ADJ
bioscience-271	248	6	damage	damage	NOUN
bioscience-271	248	7	in	in	ADP
bioscience-271	248	8	the	the	DET
bioscience-271	248	9	forebrain	forebrain	NOUN
bioscience-271	248	10	,	,	PUNCT
bioscience-271	248	11	midbrain	midbrain	NOUN
bioscience-271	248	12	,	,	PUNCT
bioscience-271	248	13	and	and	CCONJ
bioscience-271	248	14	cerebellum	cerebellum	NOUN
bioscience-271	248	15	,	,	PUNCT
bioscience-271	248	16	with	with	SCONJ
bioscience-271	248	17	tissue	tissue	NOUN
bioscience-271	248	18	architecture	architecture	NOUN
bioscience-271	248	19	almost	almost	ADV
bioscience-271	248	20	normalized	normalize	VERB
bioscience-271	248	21	on	on	ADP
bioscience-271	248	22	dpi	dpi	PROPN
bioscience-271	248	23	21	21	NUM
bioscience-271	248	24	.	.	PUNCT
bioscience-271	249	1	the	the	DET
bioscience-271	249	2	results	result	NOUN
bioscience-271	249	3	implied	imply	VERB
bioscience-271	249	4	that	that	SCONJ
bioscience-271	249	5	oa	oa	PROPN
bioscience-271	249	6	is	be	AUX
bioscience-271	249	7	efficacious	efficacious	ADJ
bioscience-271	249	8	and	and	CCONJ
bioscience-271	249	9	can	can	AUX
bioscience-271	249	10	be	be	AUX
bioscience-271	249	11	used	use	VERB
bioscience-271	249	12	in	in	ADP
bioscience-271	249	13	treating	treat	VERB
bioscience-271	249	14	tilapia	tilapia	NOUN
bioscience-271	249	15	against	against	ADP
bioscience-271	249	16	s.	s.	PROPN
bioscience-271	249	17	agalactiae	agalactiae	PROPN
bioscience-271	249	18	infection	infection	NOUN
bioscience-271	249	19	.	.	PUNCT
bioscience-271	250	1	however	however	ADV
bioscience-271	250	2	,	,	PUNCT
bioscience-271	250	3	the	the	DET
bioscience-271	250	4	world	world	PROPN
bioscience-271	250	5	health	health	NOUN
bioscience-271	250	6	organisation	organisation	NOUN
bioscience-271	250	7	stated	state	VERB
bioscience-271	250	8	that	that	SCONJ
bioscience-271	250	9	quinolones	quinolone	NOUN
bioscience-271	250	10	,	,	PUNCT
bioscience-271	250	11	including	include	VERB
bioscience-271	250	12	oa	oa	NOUN
bioscience-271	250	13	,	,	PUNCT
bioscience-271	250	14	are	be	AUX
bioscience-271	250	15	critically	critically	ADV
bioscience-271	250	16	important	important	ADJ
bioscience-271	250	17	human	human	ADJ
bioscience-271	250	18	medicines	medicine	NOUN
bioscience-271	250	19	,	,	PUNCT
bioscience-271	250	20	and	and	CCONJ
bioscience-271	250	21	they	they	PRON
bioscience-271	250	22	should	should	AUX
bioscience-271	250	23	at	at	ADP
bioscience-271	250	24	no	no	DET
bioscience-271	250	25	time	time	NOUN
bioscience-271	250	26	be	be	AUX
bioscience-271	250	27	used	use	VERB
bioscience-271	250	28	in	in	ADP
bioscience-271	250	29	animals	animal	NOUN
bioscience-271	250	30	produced	produce	VERB
bioscience-271	250	31	for	for	ADP
bioscience-271	250	32	food	food	NOUN
bioscience-271	250	33	as	as	ADP
bioscience-271	250	34	a	a	DET
bioscience-271	250	35	primary	primary	ADJ
bioscience-271	250	36	treatment	treatment	NOUN
bioscience-271	250	37	agent	agent	NOUN
bioscience-271	250	38	.	.	PUNCT
bioscience-271	251	1	based	base	VERB
bioscience-271	251	2	on	on	ADP
bioscience-271	251	3	the	the	DET
bioscience-271	251	4	results	result	NOUN
bioscience-271	251	5	,	,	PUNCT
bioscience-271	251	6	we	we	PRON
bioscience-271	251	7	advocate	advocate	VERB
bioscience-271	251	8	the	the	DET
bioscience-271	251	9	use	use	NOUN
bioscience-271	251	10	of	of	ADP
bioscience-271	251	11	oa	oa	PRON
bioscience-271	251	12	as	as	ADP
bioscience-271	251	13	a	a	DET
bioscience-271	251	14	therapeutic	therapeutic	ADJ
bioscience-271	251	15	agent	agent	NOUN
bioscience-271	251	16	for	for	ADP
bioscience-271	251	17	second	second	ADJ
bioscience-271	251	18	-	-	PUNCT
bioscience-271	251	19	line	line	NOUN
bioscience-271	251	20	treatment	treatment	NOUN
bioscience-271	251	21	in	in	ADP
bioscience-271	251	22	food	food	NOUN
bioscience-271	251	23	-	-	PUNCT
bioscience-271	251	24	producing	produce	VERB
bioscience-271	251	25	animals	animal	NOUN
bioscience-271	251	26	following	follow	VERB
bioscience-271	251	27	the	the	DET
bioscience-271	251	28	national	national	ADJ
bioscience-271	251	29	and	and	CCONJ
bioscience-271	251	30	international	international	ADJ
bioscience-271	251	31	criteria	criterion	NOUN
bioscience-271	251	32	.	.	PUNCT
bioscience-271	252	1	yet	yet	ADV
bioscience-271	252	2	,	,	PUNCT
bioscience-271	252	3	a	a	DET
bioscience-271	252	4	prudent	prudent	ADJ
bioscience-271	252	5	and	and	CCONJ
bioscience-271	252	6	responsible	responsible	ADJ
bioscience-271	252	7	use	use	NOUN
bioscience-271	252	8	of	of	ADP
bioscience-271	252	9	antibiotics	antibiotic	NOUN
bioscience-271	252	10	,	,	PUNCT
bioscience-271	252	11	targeted	target	VERB
bioscience-271	252	12	therapeutic	therapeutic	ADJ
bioscience-271	252	13	applications	application	NOUN
bioscience-271	252	14	for	for	ADP
bioscience-271	252	15	treating	treat	VERB
bioscience-271	252	16	s.	s.	PROPN
bioscience-271	252	17	agalactiae	agalactiae	PROPN
bioscience-271	252	18	-	-	PUNCT
bioscience-271	252	19	induced	induce	VERB
bioscience-271	252	20	meningitis	meningitis	NOUN
bioscience-271	252	21	in	in	ADP
bioscience-271	252	22	fish	fish	NOUN
bioscience-271	252	23	and	and	CCONJ
bioscience-271	252	24	implementing	implement	VERB
bioscience-271	252	25	long	long	ADJ
bioscience-271	252	26	-	-	PUNCT
bioscience-271	252	27	term	term	NOUN
bioscience-271	252	28	amr	amr	NOUN
bioscience-271	252	29	and	and	CCONJ
bioscience-271	252	30	residue	residue	NOUN
bioscience-271	252	31	surveillance	surveillance	NOUN
bioscience-271	252	32	to	to	PART
bioscience-271	252	33	safeguard	safeguard	VERB
bioscience-271	252	34	public	public	ADJ
bioscience-271	252	35	health	health	NOUN
bioscience-271	252	36	are	be	AUX
bioscience-271	252	37	obligatory	obligatory	ADJ
bioscience-271	252	38	.	.	PUNCT
bioscience-271	253	1	data	datum	NOUN
bioscience-271	253	2	availability	availability	NOUN
bioscience-271	253	3	statement	statement	NOUN
bioscience-271	253	4	all	all	DET
bioscience-271	253	5	relevant	relevant	ADJ
bioscience-271	253	6	data	datum	NOUN
bioscience-271	253	7	are	be	AUX
bioscience-271	253	8	within	within	ADP
bioscience-271	253	9	the	the	DET
bioscience-271	253	10	paper	paper	NOUN
bioscience-271	253	11	and	and	CCONJ
bioscience-271	253	12	supplementary	supplementary	ADJ
bioscience-271	253	13	materials	material	NOUN
bioscience-271	253	14	.	.	PUNCT
bioscience-271	254	1	funding	fund	VERB
bioscience-271	254	2	the	the	DET
bioscience-271	254	3	work	work	NOUN
bioscience-271	254	4	was	be	AUX
bioscience-271	254	5	supported	support	VERB
bioscience-271	254	6	by	by	ADP
bioscience-271	254	7	the	the	DET
bioscience-271	254	8	indian	indian	PROPN
bioscience-271	254	9	council	council	PROPN
bioscience-271	254	10	of	of	ADP
bioscience-271	254	11	agricultural	agricultural	ADJ
bioscience-271	254	12	research	research	NOUN
bioscience-271	254	13	,	,	PUNCT
bioscience-271	254	14	government	government	NOUN
bioscience-271	254	15	of	of	ADP
bioscience-271	254	16	india	india	PROPN
bioscience-271	254	17	,	,	PUNCT
bioscience-271	254	18	new	new	ADJ
bioscience-271	254	19	delhi	delhi	PROPN
bioscience-271	254	20	,	,	PUNCT
bioscience-271	254	21	under	under	ADP
bioscience-271	254	22	the	the	DET
bioscience-271	254	23	all	all	DET
bioscience-271	254	24	-	-	PUNCT
bioscience-271	254	25	india	india	PROPN
bioscience-271	254	26	network	network	NOUN
bioscience-271	254	27	project	project	NOUN
bioscience-271	254	28	on	on	ADP
bioscience-271	254	29	fish	fish	NOUN
bioscience-271	254	30	health	health	NOUN
bioscience-271	254	31	vide	vide	NOUN
bioscience-271	254	32	grant	grant	PROPN
bioscience-271	254	33	f.	f.	PROPN
bioscience-271	254	34	no	no	PROPN
bioscience-271	254	35	.	.	PUNCT
bioscience-271	255	1	ciba	ciba	PROPN
bioscience-271	255	2	/	/	SYM
bioscience-271	255	3	ainpfh/2015	ainpfh/2015	PROPN
bioscience-271	255	4	-	-	PUNCT
bioscience-271	255	5	16	16	NUM
bioscience-271	255	6	dated	date	VERB
bioscience-271	255	7	02	02	NUM
bioscience-271	255	8	june	june	PROPN
bioscience-271	255	9	2015	2015	NUM
bioscience-271	255	10	.	.	PUNCT
bioscience-271	256	1	competing	compete	VERB
bioscience-271	256	2	interests	interest	NOUN
bioscience-271	256	3	the	the	DET
bioscience-271	256	4	authors	author	NOUN
bioscience-271	256	5	declare	declare	VERB
bioscience-271	256	6	that	that	SCONJ
bioscience-271	256	7	they	they	PRON
bioscience-271	256	8	have	have	VERB
bioscience-271	256	9	no	no	DET
bioscience-271	256	10	competing	compete	VERB
bioscience-271	256	11	interests	interest	NOUN
bioscience-271	256	12	.	.	PUNCT
bioscience-271	257	1	reference	reference	NOUN
bioscience-271	257	2	1	1	NUM
bioscience-271	257	3	.	.	PUNCT
bioscience-271	257	4	fao	fao	NOUN
bioscience-271	257	5	.	.	PUNCT
bioscience-271	258	1	the	the	DET
bioscience-271	258	2	state	state	NOUN
bioscience-271	258	3	of	of	ADP
bioscience-271	258	4	world	world	NOUN
bioscience-271	258	5	fisheries	fishery	NOUN
bioscience-271	258	6	and	and	CCONJ
bioscience-271	258	7	aquaculture	aquaculture	NOUN
bioscience-271	258	8	2024	2024	NUM
bioscience-271	258	9	blue	blue	ADJ
bioscience-271	258	10	transformation	transformation	NOUN
bioscience-271	258	11	in	in	ADP
bioscience-271	258	12	action	action	NOUN
bioscience-271	258	13	.	.	PUNCT
bioscience-271	259	1	rome	rome	PROPN
bioscience-271	259	2	:	:	PUNCT
bioscience-271	259	3	food	food	NOUN
bioscience-271	259	4	and	and	CCONJ
bioscience-271	259	5	agriculture	agriculture	NOUN
bioscience-271	259	6	organization	organization	NOUN
bioscience-271	259	7	of	of	ADP
bioscience-271	259	8	the	the	DET
bioscience-271	259	9	united	united	PROPN
bioscience-271	259	10	nations	nations	PROPN
bioscience-271	259	11	;	;	PUNCT
bioscience-271	259	12	2024	2024	NUM
bioscience-271	259	13	.	.	PUNCT
bioscience-271	260	1	available	available	ADJ
bioscience-271	260	2	from	from	ADP
bioscience-271	260	3	:	:	PUNCT
bioscience-271	260	4	https://doi.org/10.4060/cd0683en	https://doi.org/10.4060/cd0683en	NOUN
bioscience-271	260	5	.	.	PUNCT
bioscience-271	261	1	2	2	X
bioscience-271	261	2	.	.	X
bioscience-271	261	3	el	el	PROPN
bioscience-271	261	4	-	-	PUNCT
bioscience-271	261	5	sayed	say	VERB
bioscience-271	261	6	afm	afm	PROPN
bioscience-271	261	7	.	.	PUNCT
bioscience-271	261	8	tilapia	tilapia	NOUN
bioscience-271	261	9	culture	culture	NOUN
bioscience-271	261	10	.	.	PUNCT
bioscience-271	262	1	2nd	2nd	ADJ
bioscience-271	262	2	ed	ed	NOUN
bioscience-271	262	3	.	.	PUNCT
bioscience-271	263	1	london	london	PROPN
bioscience-271	263	2	:	:	PUNCT
bioscience-271	263	3	academic	academic	ADJ
bioscience-271	263	4	press	press	NOUN
bioscience-271	263	5	;	;	PUNCT
bioscience-271	263	6	2019	2019	NUM
bioscience-271	263	7	.	.	PUNCT
bioscience-271	264	1	available	available	ADJ
bioscience-271	264	2	from	from	ADP
bioscience-271	264	3	:	:	PUNCT
bioscience-271	264	4	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	264	5	.	.	PUNCT
bioscience-271	265	1	1079/9780851990149.0000	1079/9780851990149.0000	NUM
bioscience-271	265	2	.	.	PUNCT
bioscience-271	266	1	3	3	X
bioscience-271	266	2	.	.	X
bioscience-271	266	3	haenen	haenen	PROPN
bioscience-271	266	4	ol	ol	PROPN
bioscience-271	266	5	,	,	PUNCT
bioscience-271	266	6	dong	dong	PROPN
bioscience-271	266	7	ht	ht	PROPN
bioscience-271	266	8	,	,	PUNCT
bioscience-271	266	9	hoai	hoai	PROPN
bioscience-271	266	10	td	td	NOUN
bioscience-271	266	11	,	,	PUNCT
bioscience-271	266	12	crumlish	crumlish	PROPN
bioscience-271	266	13	m	m	PROPN
bioscience-271	266	14	,	,	PUNCT
bioscience-271	266	15	karunasagar	karunasagar	PROPN
bioscience-271	266	16	i	i	PROPN
bioscience-271	266	17	,	,	PUNCT
bioscience-271	266	18	barkham	barkham	PROPN
bioscience-271	266	19	t	t	PROPN
bioscience-271	266	20	,	,	PUNCT
bioscience-271	266	21	et	et	PROPN
bioscience-271	266	22	al	al	PROPN
bioscience-271	266	23	.	.	PUNCT
bioscience-271	267	1	bacterial	bacterial	ADJ
bioscience-271	267	2	diseases	disease	NOUN
bioscience-271	267	3	of	of	ADP
bioscience-271	267	4	tilapia	tilapia	NOUN
bioscience-271	267	5	,	,	PUNCT
bioscience-271	267	6	their	their	PRON
bioscience-271	267	7	zoonotic	zoonotic	ADJ
bioscience-271	267	8	potential	potential	NOUN
bioscience-271	267	9	and	and	CCONJ
bioscience-271	267	10	risk	risk	NOUN
bioscience-271	267	11	of	of	ADP
bioscience-271	267	12	antimicrobial	antimicrobial	ADJ
bioscience-271	267	13	resistance	resistance	NOUN
bioscience-271	267	14	.	.	PUNCT
bioscience-271	268	1	reviews	review	NOUN
bioscience-271	268	2	in	in	ADP
bioscience-271	268	3	aquaculture	aquaculture	NOUN
bioscience-271	268	4	.	.	PUNCT
bioscience-271	269	1	2023;15:154	2023;15:154	NUM
bioscience-271	269	2	-	-	SYM
bioscience-271	269	3	85	85	NUM
bioscience-271	269	4	.	.	PUNCT
bioscience-271	269	5	available	available	ADJ
bioscience-271	269	6	from	from	ADP
bioscience-271	269	7	:	:	PUNCT
bioscience-271	269	8	https://	https://	PROPN
bioscience-271	269	9	doi.org/10.1111/raq.12743	doi.org/10.1111/raq.12743	PROPN
bioscience-271	269	10	.	.	PUNCT
bioscience-271	270	1	4	4	X
bioscience-271	270	2	.	.	X
bioscience-271	270	3	zhang	zhang	PROPN
bioscience-271	270	4	z.	z.	PROPN
bioscience-271	270	5	research	research	PROPN
bioscience-271	270	6	advances	advance	NOUN
bioscience-271	270	7	on	on	ADP
bioscience-271	270	8	tilapia	tilapia	NOUN
bioscience-271	270	9	streptococcosis	streptococcosis	NOUN
bioscience-271	270	10	.	.	PUNCT
bioscience-271	271	1	pathogens	pathogen	NOUN
bioscience-271	271	2	.	.	PUNCT
bioscience-271	272	1	2021;10(5):550	2021;10(5):550	NUM
bioscience-271	272	2	-	-	SYM
bioscience-271	272	3	8	8	NUM
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bioscience-271	272	5	available	available	ADJ
bioscience-271	272	6	from	from	ADP
bioscience-271	272	7	:	:	PUNCT
bioscience-271	272	8	https	https	NOUN
bioscience-271	272	9	:	:	PUNCT
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bioscience-271	273	2	.	.	X
bioscience-271	273	3	adikesavalu	adikesavalu	PROPN
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bioscience-271	273	8	,	,	PUNCT
bioscience-271	273	9	patra	patra	PROPN
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bioscience-271	273	12	abraham	abraham	PROPN
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bioscience-271	273	14	.	.	PUNCT
bioscience-271	274	1	meningoencephalitis	meningoencephalitis	PROPN
bioscience-271	274	2	in	in	ADP
bioscience-271	274	3	farmed	farm	VERB
bioscience-271	274	4	monosex	monosex	PROPN
bioscience-271	274	5	nile	nile	PROPN
bioscience-271	274	6	tilapia	tilapia	PROPN
bioscience-271	274	7	(	(	PUNCT
bioscience-271	274	8	oreochromis	oreochromis	PROPN
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bioscience-271	274	11	)	)	PUNCT
bioscience-271	274	12	caused	cause	VERB
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bioscience-271	274	14	streptococcus	streptococcus	NOUN
bioscience-271	274	15	agalactiae	agalactiae	NOUN
bioscience-271	274	16	.	.	PUNCT
bioscience-271	275	1	fisheries	fishery	NOUN
bioscience-271	275	2	and	and	CCONJ
bioscience-271	275	3	aquatic	aquatic	ADJ
bioscience-271	275	4	life	life	NOUN
bioscience-271	275	5	.	.	PUNCT
bioscience-271	276	1	2017;5(3):187	2017;5(3):187	NUM
bioscience-271	276	2	-	-	SYM
bioscience-271	276	3	200	200	NUM
bioscience-271	276	4	.	.	PUNCT
bioscience-271	276	5	available	available	ADJ
bioscience-271	276	6	from	from	ADP
bioscience-271	276	7	:	:	PUNCT
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bioscience-271	277	5	,	,	PUNCT
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bioscience-271	277	9	de	de	PROPN
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bioscience-271	277	12	,	,	PUNCT
bioscience-271	277	13	da	da	PROPN
bioscience-271	277	14	costa	costa	PROPN
bioscience-271	277	15	-	-	PUNCT
bioscience-271	277	16	alecrim	alecrim	NOUN
bioscience-271	277	17	jv	jv	PROPN
bioscience-271	277	18	,	,	PUNCT
bioscience-271	277	19	de	de	PROPN
bioscience-271	277	20	souza	souza	PROPN
bioscience-271	277	21	pg	pg	PROPN
bioscience-271	277	22	,	,	PUNCT
bioscience-271	277	23	de	de	PROPN
bioscience-271	277	24	carvalho	carvalho	PROPN
bioscience-271	277	25	fca	fca	PROPN
bioscience-271	277	26	,	,	PUNCT
bioscience-271	277	27	et	et	PROPN
bioscience-271	277	28	al	al	PROPN
bioscience-271	277	29	.	.	PROPN
bioscience-271	278	1	meningitis	meningitis	PROPN
bioscience-271	278	2	caused	cause	VERB
bioscience-271	278	3	highlights	highlight	NOUN
bioscience-271	278	4	in	in	ADP
bioscience-271	278	5	bioscience	bioscience	NOUN
bioscience-271	278	6	page	page	NOUN
bioscience-271	278	7	7	7	NUM
bioscience-271	278	8	of	of	ADP
bioscience-271	278	9	10	10	NUM
bioscience-271	278	10	october	october	PROPN
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bioscience-271	278	12	8	8	NUM
bioscience-271	278	13	https://doi.org/10.4060/cd0683en	https://doi.org/10.4060/cd0683en	NOUN
bioscience-271	278	14	https://doi.org/10.1079/9780851990149.0000	https://doi.org/10.1079/9780851990149.0000	PROPN
bioscience-271	278	15	https://doi.org/10.1079/9780851990149.0000	https://doi.org/10.1079/9780851990149.0000	PROPN
bioscience-271	279	1	https://doi.org/10.1111/raq.12743	https://doi.org/10.1111/raq.12743	PROPN
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bioscience-271	279	3	https://doi.org/10.3390/pathogens10050558	https://doi.org/10.3390/pathogens10050558	PROPN
bioscience-271	279	4	https://doi.org/10.3390/pathogens10050558	https://doi.org/10.3390/pathogens10050558	PROPN
bioscience-271	279	5	https://doi.org/10.1515/aopf-2017-0018	https://doi.org/10.1515/aopf-2017-0018	PROPN
bioscience-271	280	1	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	280	2	sinha	sinha	PROPN
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bioscience-271	280	5	al	al	PROPN
bioscience-271	280	6	.	.	PROPN
bioscience-271	280	7	,	,	PUNCT
bioscience-271	280	8	2025	2025	NUM
bioscience-271	280	9	effect	effect	NOUN
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bioscience-271	280	11	oxolinic	oxolinic	ADJ
bioscience-271	280	12	acid	acid	NOUN
bioscience-271	280	13	therapy	therapy	NOUN
bioscience-271	280	14	by	by	ADP
bioscience-271	280	15	streptococcus	streptococcus	NOUN
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bioscience-271	280	17	in	in	ADP
bioscience-271	280	18	nile	nile	PROPN
bioscience-271	280	19	tilapia	tilapia	PROPN
bioscience-271	280	20	(	(	PUNCT
bioscience-271	280	21	oreochromis	oreochromis	PROPN
bioscience-271	280	22	niloticus	niloticus	PROPN
bioscience-271	280	23	):	):	PUNCT
bioscience-271	280	24	infection	infection	NOUN
bioscience-271	280	25	and	and	CCONJ
bioscience-271	280	26	inflammatory	inflammatory	ADJ
bioscience-271	280	27	response	response	NOUN
bioscience-271	280	28	.	.	PUNCT
bioscience-271	281	1	animals	animal	NOUN
bioscience-271	281	2	.	.	PUNCT
bioscience-271	282	1	2020;10:2166	2020;10:2166	NUM
bioscience-271	282	2	.	.	PUNCT
bioscience-271	282	3	available	available	ADJ
bioscience-271	282	4	from	from	ADP
bioscience-271	282	5	:	:	PUNCT
bioscience-271	282	6	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	282	7	.	.	PUNCT
bioscience-271	282	8	3390	3390	NUM
bioscience-271	282	9	/	/	SYM
bioscience-271	282	10	ani10112166	ani10112166	NOUN
bioscience-271	282	11	.	.	PUNCT
bioscience-271	283	1	7	7	X
bioscience-271	283	2	.	.	X
bioscience-271	283	3	syuhada	syuhada	PROPN
bioscience-271	283	4	rm	rm	PROPN
bioscience-271	283	5	,	,	PUNCT
bioscience-271	283	6	zamri	zamri	PROPN
bioscience-271	283	7	-	-	PUNCT
bioscience-271	283	8	saad	saad	PROPN
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bioscience-271	283	10	,	,	PUNCT
bioscience-271	283	11	ina	ina	PROPN
bioscience-271	283	12	-	-	PUNCT
bioscience-271	283	13	salwany	salwany	NOUN
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bioscience-271	283	16	mustafa	mustafa	PROPN
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bioscience-271	283	18	,	,	PUNCT
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bioscience-271	283	20	mnm	mnm	PROPN
bioscience-271	283	21	,	,	PUNCT
bioscience-271	283	22	desa	desa	PROPN
bioscience-271	283	23	sa	sa	PROPN
bioscience-271	283	24	,	,	PUNCT
bioscience-271	283	25	et	et	PROPN
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bioscience-271	283	27	.	.	PUNCT
bioscience-271	284	1	molecular	molecular	ADJ
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bioscience-271	284	3	and	and	CCONJ
bioscience-271	284	4	pathogenicity	pathogenicity	NOUN
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bioscience-271	284	6	streptococcus	streptococcus	NOUN
bioscience-271	284	7	agalactiae	agalactiae	PROPN
bioscience-271	284	8	serotypes	serotype	NOUN
bioscience-271	284	9	ia	ia	PROPN
bioscience-271	284	10	st7	st7	PROPN
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bioscience-271	284	12	iii	iii	PROPN
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bioscience-271	284	15	from	from	ADP
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bioscience-271	284	17	red	red	ADJ
bioscience-271	284	18	hybrid	hybrid	ADJ
bioscience-271	284	19	tilapia	tilapia	NOUN
bioscience-271	284	20	in	in	ADP
bioscience-271	284	21	malaysia	malaysia	PROPN
bioscience-271	284	22	.	.	PUNCT
bioscience-271	284	23	aquaculture	aquaculture	PROPN
bioscience-271	284	24	.	.	PUNCT
bioscience-271	285	1	2020;515:734543	2020;515:734543	X
bioscience-271	285	2	.	.	PUNCT
bioscience-271	285	3	available	available	ADJ
bioscience-271	285	4	from	from	ADP
bioscience-271	285	5	:	:	PUNCT
bioscience-271	285	6	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	285	7	.	.	PUNCT
bioscience-271	286	1	1016	1016	NUM
bioscience-271	286	2	/	/	SYM
bioscience-271	286	3	j.aquaculture.2019.734543	j.aquaculture.2019.734543	NOUN
bioscience-271	286	4	.	.	PUNCT
bioscience-271	287	1	8	8	X
bioscience-271	287	2	.	.	PUNCT
bioscience-271	287	3	cao	cao	PROPN
bioscience-271	287	4	jz	jz	PROPN
bioscience-271	287	5	,	,	PUNCT
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bioscience-271	287	8	,	,	PUNCT
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bioscience-271	287	13	f	f	PROPN
bioscience-271	287	14	,	,	PUNCT
bioscience-271	287	15	gao	gao	PROPN
bioscience-271	287	16	m	m	PROPN
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bioscience-271	287	18	wang	wang	PROPN
bioscience-271	287	19	m	m	PROPN
bioscience-271	287	20	,	,	PUNCT
bioscience-271	287	21	et	et	PROPN
bioscience-271	287	22	al	al	PROPN
bioscience-271	287	23	.	.	PUNCT
bioscience-271	287	24	distribution	distribution	NOUN
bioscience-271	287	25	and	and	CCONJ
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bioscience-271	287	28	streptococcus	streptococcus	NOUN
bioscience-271	287	29	agalactiae	agalactiae	NOUN
bioscience-271	287	30	in	in	ADP
bioscience-271	287	31	different	different	ADJ
bioscience-271	287	32	tissues	tissue	NOUN
bioscience-271	287	33	of	of	ADP
bioscience-271	287	34	artificially	artificially	ADV
bioscience-271	287	35	infected	infect	VERB
bioscience-271	287	36	tilapia	tilapia	NOUN
bioscience-271	287	37	(	(	PUNCT
bioscience-271	287	38	oreochromis	oreochromis	NOUN
bioscience-271	287	39	niloticus	niloticus	PROPN
bioscience-271	287	40	)	)	PUNCT
bioscience-271	287	41	.	.	PUNCT
bioscience-271	288	1	aquaculture	aquaculture	NOUN
bioscience-271	288	2	.	.	PUNCT
bioscience-271	289	1	2022;546:737370	2022;546:737370	X
bioscience-271	289	2	.	.	PUNCT
bioscience-271	290	1	available	available	ADJ
bioscience-271	290	2	from	from	ADP
bioscience-271	290	3	:	:	PUNCT
bioscience-271	290	4	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	290	5	.	.	PUNCT
bioscience-271	291	1	1016	1016	NUM
bioscience-271	291	2	/	/	SYM
bioscience-271	291	3	j.aquaculture.2021.737370	j.aquaculture.2021.737370	NOUN
bioscience-271	291	4	.	.	PUNCT
bioscience-271	292	1	9	9	X
bioscience-271	292	2	.	.	X
bioscience-271	292	3	palang	palang	PROPN
bioscience-271	292	4	i	i	PROPN
bioscience-271	292	5	,	,	PUNCT
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bioscience-271	292	7	b	b	AUX
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bioscience-271	292	11	,	,	PUNCT
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bioscience-271	292	14	,	,	PUNCT
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bioscience-271	292	18	histopathology	histopathology	NOUN
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bioscience-271	292	30	serotype	serotype	PROPN
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bioscience-271	292	35	and	and	CCONJ
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bioscience-271	292	37	.	.	PUNCT
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bioscience-271	293	4	.	.	PUNCT
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bioscience-271	293	7	:	:	PUNCT
bioscience-271	293	8	https://doi.org/	https://doi.org/	NOUN
bioscience-271	293	9	10.1002	10.1002	NUM
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bioscience-271	293	14	.	.	PUNCT
bioscience-271	294	1	world	world	PROPN
bioscience-271	294	2	health	health	PROPN
bioscience-271	294	3	organization	organization	NOUN
bioscience-271	294	4	(	(	PUNCT
bioscience-271	294	5	who	who	PRON
bioscience-271	294	6	)	)	PUNCT
bioscience-271	294	7	.	.	PUNCT
bioscience-271	295	1	critically	critically	ADV
bioscience-271	295	2	important	important	ADJ
bioscience-271	295	3	antimicrobials	antimicrobial	NOUN
bioscience-271	295	4	for	for	ADP
bioscience-271	295	5	human	human	ADJ
bioscience-271	295	6	medicine	medicine	NOUN
bioscience-271	295	7	,	,	PUNCT
bioscience-271	295	8	6th	6th	ADJ
bioscience-271	295	9	revision	revision	NOUN
bioscience-271	295	10	.	.	PUNCT
bioscience-271	296	1	geneva	geneva	PROPN
bioscience-271	296	2	;	;	PUNCT
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bioscience-271	296	4	.	.	PUNCT
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bioscience-271	296	6	:	:	PUNCT
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bioscience-271	296	8	-	-	SYM
bioscience-271	296	9	10	10	NUM
bioscience-271	296	10	-	-	SYM
bioscience-271	296	11	12	12	NUM
bioscience-271	296	12	.	.	PUNCT
bioscience-271	297	1	available	available	ADJ
bioscience-271	297	2	from	from	ADP
bioscience-271	297	3	:	:	PUNCT
bioscience-271	297	4	https://www.who.int/publications/i/item/	https://www.who.int/publications/i/item/	NOUN
bioscience-271	297	5	9789241515528	9789241515528	NUM
bioscience-271	297	6	.	.	PUNCT
bioscience-271	298	1	11	11	NUM
bioscience-271	298	2	.	.	PUNCT
bioscience-271	299	1	lulijwa	lulijwa	NOUN
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bioscience-271	299	9	.	.	PUNCT
bioscience-271	300	1	antibiotic	antibiotic	ADJ
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bioscience-271	300	4	aquaculture	aquaculture	NOUN
bioscience-271	300	5	,	,	PUNCT
bioscience-271	300	6	policies	policy	NOUN
bioscience-271	300	7	and	and	CCONJ
bioscience-271	300	8	regulation	regulation	NOUN
bioscience-271	300	9	,	,	PUNCT
bioscience-271	300	10	health	health	NOUN
bioscience-271	300	11	and	and	CCONJ
bioscience-271	300	12	environmental	environmental	ADJ
bioscience-271	300	13	risks	risk	NOUN
bioscience-271	300	14	:	:	PUNCT
bioscience-271	300	15	a	a	DET
bioscience-271	300	16	review	review	NOUN
bioscience-271	300	17	of	of	ADP
bioscience-271	300	18	the	the	DET
bioscience-271	300	19	top	top	ADJ
bioscience-271	300	20	15	15	NUM
bioscience-271	300	21	major	major	ADJ
bioscience-271	300	22	producers	producer	NOUN
bioscience-271	300	23	.	.	PUNCT
bioscience-271	301	1	reviews	review	NOUN
bioscience-271	301	2	in	in	ADP
bioscience-271	301	3	aquaculture	aquaculture	NOUN
bioscience-271	301	4	.	.	PUNCT
bioscience-271	302	1	2020;12:640	2020;12:640	VERB
bioscience-271	302	2	-	-	SYM
bioscience-271	302	3	63	63	NUM
bioscience-271	302	4	.	.	PUNCT
bioscience-271	303	1	available	available	ADJ
bioscience-271	303	2	from	from	ADP
bioscience-271	303	3	:	:	PUNCT
bioscience-271	303	4	https://doi.org/10.1111/raq.12344	https://doi.org/10.1111/raq.12344	PROPN
bioscience-271	303	5	.	.	PUNCT
bioscience-271	304	1	12	12	NUM
bioscience-271	304	2	.	.	PUNCT
bioscience-271	305	1	schar	schar	PROPN
bioscience-271	305	2	d	d	PROPN
bioscience-271	305	3	,	,	PUNCT
bioscience-271	305	4	klein	klein	PROPN
bioscience-271	305	5	ey	ey	PROPN
bioscience-271	305	6	,	,	PUNCT
bioscience-271	305	7	laxminarayan	laxminarayan	PROPN
bioscience-271	305	8	r	r	PROPN
bioscience-271	305	9	,	,	PUNCT
bioscience-271	305	10	gilbert	gilbert	PROPN
bioscience-271	305	11	m	m	PROPN
bioscience-271	305	12	,	,	PUNCT
bioscience-271	305	13	van	van	PROPN
bioscience-271	305	14	boeckel	boeckel	PROPN
bioscience-271	305	15	tp	tp	PROPN
bioscience-271	305	16	.	.	PUNCT
bioscience-271	306	1	global	global	ADJ
bioscience-271	306	2	trends	trend	NOUN
bioscience-271	306	3	in	in	ADP
bioscience-271	306	4	antimicrobial	antimicrobial	ADJ
bioscience-271	306	5	use	use	NOUN
bioscience-271	306	6	in	in	ADP
bioscience-271	306	7	aquaculture	aquaculture	NOUN
bioscience-271	306	8	.	.	PUNCT
bioscience-271	307	1	scientific	scientific	ADJ
bioscience-271	307	2	reports	report	NOUN
bioscience-271	307	3	.	.	PUNCT
bioscience-271	308	1	2020;10:21878	2020;10:21878	NUM
bioscience-271	308	2	.	.	PUNCT
bioscience-271	308	3	available	available	ADJ
bioscience-271	308	4	from	from	ADP
bioscience-271	308	5	:	:	PUNCT
bioscience-271	308	6	https	https	NOUN
bioscience-271	308	7	:	:	PUNCT
bioscience-271	308	8	//doi.org/10.1038	//doi.org/10.1038	PROPN
bioscience-271	308	9	/	/	SYM
bioscience-271	308	10	s41598	s41598	NOUN
bioscience-271	308	11	-	-	PUNCT
bioscience-271	308	12	020	020	NUM
bioscience-271	308	13	-	-	PUNCT
bioscience-271	308	14	78849	78849	NUM
bioscience-271	308	15	-	-	SYM
bioscience-271	308	16	3	3	NUM
bioscience-271	308	17	.	.	NOUN
bioscience-271	308	18	13	13	NUM
bioscience-271	308	19	.	.	PUNCT
bioscience-271	309	1	world	world	NOUN
bioscience-271	309	2	organisation	organisation	NOUN
bioscience-271	309	3	for	for	ADP
bioscience-271	309	4	animal	animal	NOUN
bioscience-271	309	5	health	health	NOUN
bioscience-271	309	6	(	(	PUNCT
bioscience-271	309	7	woah	woah	NOUN
bioscience-271	309	8	)	)	PUNCT
bioscience-271	309	9	.	.	PUNCT
bioscience-271	310	1	annual	annual	ADJ
bioscience-271	310	2	report	report	NOUN
bioscience-271	310	3	on	on	ADP
bioscience-271	310	4	antimicrobial	antimicrobial	ADJ
bioscience-271	310	5	agents	agent	NOUN
bioscience-271	310	6	intended	intend	VERB
bioscience-271	310	7	for	for	ADP
bioscience-271	310	8	use	use	NOUN
bioscience-271	310	9	in	in	ADP
bioscience-271	310	10	animals	animal	NOUN
bioscience-271	310	11	,	,	PUNCT
bioscience-271	310	12	8th	8th	ADJ
bioscience-271	310	13	report	report	NOUN
bioscience-271	310	14	.	.	PUNCT
bioscience-271	311	1	paris	paris	PROPN
bioscience-271	311	2	;	;	PUNCT
bioscience-271	311	3	2024	2024	NUM
bioscience-271	311	4	.	.	PUNCT
bioscience-271	312	1	44	44	NUM
bioscience-271	312	2	p	p	NOUN
bioscience-271	312	3	,	,	PUNCT
bioscience-271	312	4	accessed	access	VERB
bioscience-271	312	5	:	:	PUNCT
bioscience-271	312	6	2025	2025	NUM
bioscience-271	312	7	-	-	SYM
bioscience-271	312	8	10	10	NUM
bioscience-271	312	9	-	-	SYM
bioscience-271	312	10	12	12	NUM
bioscience-271	312	11	.	.	PUNCT
bioscience-271	313	1	available	available	ADJ
bioscience-271	313	2	from	from	ADP
bioscience-271	313	3	:	:	PUNCT
bioscience-271	313	4	https://doi.org/10.20506/amu.3474	https://doi.org/10.20506/amu.3474	PROPN
bioscience-271	313	5	.	.	PROPN
bioscience-271	313	6	14	14	NUM
bioscience-271	313	7	.	.	PUNCT
bioscience-271	314	1	united	united	PROPN
bioscience-271	314	2	states	states	PROPN
bioscience-271	314	3	food	food	PROPN
bioscience-271	314	4	and	and	CCONJ
bioscience-271	314	5	drug	drug	PROPN
bioscience-271	314	6	administration	administration	PROPN
bioscience-271	314	7	(	(	PUNCT
bioscience-271	314	8	usfda	usfda	PROPN
bioscience-271	314	9	)	)	PUNCT
bioscience-271	314	10	.	.	PUNCT
bioscience-271	315	1	approved	approve	VERB
bioscience-271	315	2	aquaculture	aquaculture	NOUN
bioscience-271	315	3	drugs	drug	NOUN
bioscience-271	315	4	.	.	PUNCT
bioscience-271	316	1	silver	silver	ADJ
bioscience-271	316	2	spring	spring	PROPN
bioscience-271	316	3	,	,	PUNCT
bioscience-271	316	4	md	md	PROPN
bioscience-271	316	5	;	;	PUNCT
bioscience-271	316	6	2024	2024	NUM
bioscience-271	316	7	.	.	PUNCT
bioscience-271	316	8	accessed	access	VERB
bioscience-271	316	9	:	:	PUNCT
bioscience-271	316	10	2023	2023	NUM
bioscience-271	316	11	-	-	SYM
bioscience-271	316	12	03	03	NUM
bioscience-271	316	13	-	-	SYM
bioscience-271	316	14	13	13	NUM
bioscience-271	316	15	.	.	PUNCT
bioscience-271	317	1	available	available	ADJ
bioscience-271	317	2	from	from	ADP
bioscience-271	317	3	:	:	PUNCT
bioscience-271	317	4	https://www.fda.gov/animal-veterinary/	https://www.fda.gov/animal-veterinary/	X
bioscience-271	317	5	aquaculture	aquaculture	NOUN
bioscience-271	317	6	/	/	SYM
bioscience-271	317	7	approved	approve	VERB
bioscience-271	317	8	-	-	PUNCT
bioscience-271	317	9	aquaculture	aquaculture	NOUN
bioscience-271	317	10	-	-	PUNCT
bioscience-271	317	11	drugs	drug	NOUN
bioscience-271	317	12	.	.	PUNCT
bioscience-271	318	1	15	15	NUM
bioscience-271	318	2	.	.	PUNCT
bioscience-271	318	3	world	world	PROPN
bioscience-271	318	4	health	health	PROPN
bioscience-271	318	5	organization	organization	NOUN
bioscience-271	318	6	(	(	PUNCT
bioscience-271	318	7	who	who	PRON
bioscience-271	318	8	)	)	PUNCT
bioscience-271	318	9	.	.	PUNCT
bioscience-271	319	1	list	list	NOUN
bioscience-271	319	2	of	of	ADP
bioscience-271	319	3	medically	medically	ADV
bioscience-271	319	4	important	important	ADJ
bioscience-271	319	5	antimicrobials	antimicrobial	NOUN
bioscience-271	319	6	.	.	PUNCT
bioscience-271	320	1	geneva	geneva	PROPN
bioscience-271	320	2	;	;	PUNCT
bioscience-271	320	3	2024	2024	NUM
bioscience-271	320	4	.	.	PUNCT
bioscience-271	320	5	accessed	access	VERB
bioscience-271	320	6	:	:	PUNCT
bioscience-271	320	7	2025	2025	NUM
bioscience-271	320	8	-	-	SYM
bioscience-271	320	9	10	10	NUM
bioscience-271	320	10	-	-	SYM
bioscience-271	320	11	12	12	NUM
bioscience-271	320	12	.	.	PUNCT
bioscience-271	321	1	available	available	ADJ
bioscience-271	321	2	from	from	ADP
bioscience-271	321	3	:	:	PUNCT
bioscience-271	321	4	https://cdn.who.int/media/docs/	https://cdn.who.int/media/docs/	PROPN
bioscience-271	321	5	default	default	NOUN
bioscience-271	321	6	-	-	PUNCT
bioscience-271	321	7	source	source	NOUN
bioscience-271	321	8	/	/	SYM
bioscience-271	321	9	gcp	gcp	NOUN
bioscience-271	321	10	/	/	SYM
bioscience-271	321	11	who	who	PRON
bioscience-271	321	12	-	-	PUNCT
bioscience-271	321	13	mia	mia	NOUN
bioscience-271	321	14	-	-	PUNCT
bioscience-271	321	15	list-2024	list-2024	NOUN
bioscience-271	321	16	-	-	PUNCT
bioscience-271	321	17	lv.pdf	lv.pdf	NOUN
bioscience-271	321	18	.	.	PUNCT
bioscience-271	322	1	16	16	NUM
bioscience-271	322	2	.	.	PUNCT
bioscience-271	323	1	emea	emea	PROPN
bioscience-271	323	2	.	.	PUNCT
bioscience-271	323	3	committee	committee	PROPN
bioscience-271	323	4	for	for	ADP
bioscience-271	323	5	medicinal	medicinal	ADJ
bioscience-271	323	6	products	product	NOUN
bioscience-271	323	7	for	for	ADP
bioscience-271	323	8	veterinary	veterinary	ADJ
bioscience-271	323	9	use	use	NOUN
bioscience-271	323	10	:	:	PUNCT
bioscience-271	323	11	oxolinic	oxolinic	ADJ
bioscience-271	323	12	acid	acid	NOUN
bioscience-271	323	13	(	(	PUNCT
bioscience-271	323	14	extension	extension	NOUN
bioscience-271	323	15	to	to	ADP
bioscience-271	323	16	all	all	DET
bioscience-271	323	17	foodproducing	foodproduce	VERB
bioscience-271	323	18	species	specie	NOUN
bioscience-271	323	19	)	)	PUNCT
bioscience-271	323	20	.	.	PUNCT
bioscience-271	324	1	london	london	PROPN
bioscience-271	324	2	;	;	PUNCT
bioscience-271	324	3	2005	2005	NUM
bioscience-271	324	4	.	.	PUNCT
bioscience-271	325	1	available	available	ADJ
bioscience-271	325	2	from	from	ADP
bioscience-271	325	3	:	:	PUNCT
bioscience-271	325	4	https://www.ema.europa.eu/en/documents/	https://www.ema.europa.eu/en/documents/	NOUN
bioscience-271	325	5	committee	committee	NOUN
bioscience-271	325	6	-	-	PUNCT
bioscience-271	325	7	report	report	NOUN
bioscience-271	325	8	/	/	SYM
bioscience-271	325	9	committee	committee	NOUN
bioscience-271	325	10	-	-	PUNCT
bioscience-271	325	11	medicinalproducts	medicinalproduct	NOUN
bioscience-271	325	12	-	-	PUNCT
bioscience-271	325	13	veterinary	veterinary	ADJ
bioscience-271	325	14	-	-	PUNCT
bioscience-271	325	15	use	use	NOUN
bioscience-271	325	16	-	-	PUNCT
bioscience-271	325	17	cvmp	cvmp	NOUN
bioscience-271	325	18	-	-	PUNCT
bioscience-271	325	19	monthly	monthly	ADJ
bioscience-271	325	20	-	-	PUNCT
bioscience-271	325	21	reportapplication	reportapplication	NOUN
bioscience-271	325	22	-	-	PUNCT
bioscience-271	325	23	procedures	procedure	NOUN
bioscience-271	325	24	-	-	PUNCT
bioscience-271	325	25	guidelines_en-4.pdf	guidelines_en-4.pdf	NOUN
bioscience-271	325	26	.	.	PUNCT
bioscience-271	326	1	17	17	NUM
bioscience-271	326	2	.	.	PUNCT
bioscience-271	327	1	oie	oie	PROPN
bioscience-271	327	2	,	,	PUNCT
bioscience-271	327	3	list	list	NOUN
bioscience-271	327	4	of	of	ADP
bioscience-271	327	5	antimicrobial	antimicrobial	ADJ
bioscience-271	327	6	agents	agent	NOUN
bioscience-271	327	7	of	of	ADP
bioscience-271	327	8	veterinary	veterinary	ADJ
bioscience-271	327	9	importance	importance	NOUN
bioscience-271	327	10	,	,	PUNCT
bioscience-271	327	11	office	office	NOUN
bioscience-271	327	12	international	international	PROPN
bioscience-271	327	13	des	des	X
bioscience-271	327	14	epizooties	epizooties	PROPN
bioscience-271	327	15	(	(	PUNCT
bioscience-271	327	16	world	world	NOUN
bioscience-271	327	17	organization	organization	NOUN
bioscience-271	327	18	for	for	ADP
bioscience-271	327	19	animal	animal	NOUN
bioscience-271	327	20	health	health	NOUN
bioscience-271	327	21	)	)	PUNCT
bioscience-271	327	22	.	.	PUNCT
bioscience-271	328	1	paris	paris	PROPN
bioscience-271	328	2	;	;	PUNCT
bioscience-271	328	3	2019	2019	NUM
bioscience-271	328	4	.	.	PUNCT
bioscience-271	328	5	accessed	access	VERB
bioscience-271	328	6	:	:	PUNCT
bioscience-271	328	7	2025	2025	NUM
bioscience-271	328	8	-	-	SYM
bioscience-271	328	9	10	10	NUM
bioscience-271	328	10	-	-	SYM
bioscience-271	328	11	12	12	NUM
bioscience-271	328	12	.	.	PUNCT
bioscience-271	329	1	available	available	ADJ
bioscience-271	329	2	from	from	ADP
bioscience-271	329	3	:	:	PUNCT
bioscience-271	329	4	https://www.woah.org/app/uploads/2021/03/aoie-list-antimicrobials-july2019.pdf	https://www.woah.org/app/uploads/2021/03/aoie-list-antimicrobials-july2019.pdf	PROPN
bioscience-271	329	5	.	.	PUNCT
bioscience-271	329	6	18	18	NUM
bioscience-271	329	7	.	.	PUNCT
bioscience-271	330	1	world	world	NOUN
bioscience-271	330	2	organisation	organisation	NOUN
bioscience-271	330	3	for	for	ADP
bioscience-271	330	4	animal	animal	NOUN
bioscience-271	330	5	health	health	NOUN
bioscience-271	330	6	(	(	PUNCT
bioscience-271	330	7	oie	oie	PROPN
bioscience-271	330	8	)	)	PUNCT
bioscience-271	330	9	.	.	PUNCT
bioscience-271	331	1	guidelines	guideline	NOUN
bioscience-271	331	2	and	and	CCONJ
bioscience-271	331	3	resolutions	resolution	NOUN
bioscience-271	331	4	on	on	ADP
bioscience-271	331	5	antimicrobial	antimicrobial	ADJ
bioscience-271	331	6	resistance	resistance	NOUN
bioscience-271	331	7	and	and	CCONJ
bioscience-271	331	8	the	the	DET
bioscience-271	331	9	use	use	NOUN
bioscience-271	331	10	of	of	ADP
bioscience-271	331	11	antimicrobial	antimicrobial	ADJ
bioscience-271	331	12	agents	agent	NOUN
bioscience-271	331	13	.	.	PUNCT
bioscience-271	332	1	paris	paris	PROPN
bioscience-271	332	2	;	;	PUNCT
bioscience-271	332	3	2020	2020	NUM
bioscience-271	332	4	.	.	PUNCT
bioscience-271	332	5	accessed	access	VERB
bioscience-271	332	6	:	:	PUNCT
bioscience-271	332	7	2025	2025	NUM
bioscience-271	332	8	-	-	SYM
bioscience-271	332	9	1012	1012	NUM
bioscience-271	332	10	.	.	PUNCT
bioscience-271	333	1	available	available	ADJ
bioscience-271	333	2	from	from	ADP
bioscience-271	333	3	:	:	PUNCT
bioscience-271	333	4	https://www.oie.int/fileadmin/	https://www.oie.int/fileadmin/	NOUN
bioscience-271	333	5	home	home	NOUN
bioscience-271	333	6	/	/	SYM
bioscience-271	333	7	eng/.	eng/.	NOUN
bioscience-271	333	8	19	19	NUM
bioscience-271	333	9	.	.	PUNCT
bioscience-271	334	1	love	love	PROPN
bioscience-271	334	2	dc	dc	PROPN
bioscience-271	334	3	,	,	PUNCT
bioscience-271	334	4	fry	fry	NOUN
bioscience-271	334	5	jp	jp	PROPN
bioscience-271	334	6	,	,	PUNCT
bioscience-271	334	7	cabello	cabello	PROPN
bioscience-271	334	8	f	f	PROPN
bioscience-271	334	9	,	,	PUNCT
bioscience-271	334	10	good	good	ADJ
bioscience-271	334	11	cm	cm	NOUN
bioscience-271	334	12	,	,	PUNCT
bioscience-271	334	13	lunestad	lunestad	PROPN
bioscience-271	334	14	bt	bt	PROPN
bioscience-271	334	15	.	.	PROPN
bioscience-271	335	1	veterinary	veterinary	ADJ
bioscience-271	335	2	drug	drug	NOUN
bioscience-271	335	3	use	use	NOUN
bioscience-271	335	4	in	in	ADP
bioscience-271	335	5	united	united	PROPN
bioscience-271	335	6	states	states	PROPN
bioscience-271	335	7	net	net	ADJ
bioscience-271	335	8	-	-	PUNCT
bioscience-271	335	9	pen	pen	NOUN
bioscience-271	335	10	salmon	salmon	NOUN
bioscience-271	335	11	aquaculture	aquaculture	NOUN
bioscience-271	335	12	:	:	PUNCT
bioscience-271	335	13	implications	implication	NOUN
bioscience-271	335	14	for	for	ADP
bioscience-271	335	15	drug	drug	NOUN
bioscience-271	335	16	use	use	NOUN
bioscience-271	335	17	policy	policy	NOUN
bioscience-271	335	18	.	.	PUNCT
bioscience-271	336	1	aquaculture	aquaculture	NOUN
bioscience-271	336	2	.	.	PUNCT
bioscience-271	337	1	2020;518:734820	2020;518:734820	NOUN
bioscience-271	337	2	.	.	PUNCT
bioscience-271	338	1	available	available	ADJ
bioscience-271	338	2	from	from	ADP
bioscience-271	338	3	:	:	PUNCT
bioscience-271	338	4	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	338	5	.	.	PUNCT
bioscience-271	339	1	1016	1016	NUM
bioscience-271	339	2	/	/	SYM
bioscience-271	339	3	j.aquaculture.2019.734820	j.aquaculture.2019.734820	NOUN
bioscience-271	339	4	.	.	PUNCT
bioscience-271	340	1	20	20	NUM
bioscience-271	340	2	.	.	PUNCT
bioscience-271	341	1	rigos	rigo	NOUN
bioscience-271	341	2	g	g	PROPN
bioscience-271	341	3	,	,	PUNCT
bioscience-271	341	4	kogiannou	kogiannou	PROPN
bioscience-271	342	1	d	d	NOUN
bioscience-271	342	2	,	,	PUNCT
bioscience-271	342	3	padrós	padrós	PROPN
bioscience-271	342	4	f	f	NOUN
bioscience-271	342	5	,	,	PUNCT
bioscience-271	342	6	cristofol	cristofol	NOUN
bioscience-271	342	7	c	c	PROPN
bioscience-271	342	8	,	,	PUNCT
bioscience-271	342	9	florio	florio	PROPN
bioscience-271	342	10	d	d	PROPN
bioscience-271	342	11	,	,	PUNCT
bioscience-271	342	12	fioravanti	fioravanti	VERB
bioscience-271	342	13	m	m	PROPN
bioscience-271	342	14	,	,	PUNCT
bioscience-271	342	15	et	et	PROPN
bioscience-271	342	16	al	al	PROPN
bioscience-271	342	17	.	.	PUNCT
bioscience-271	343	1	best	good	ADJ
bioscience-271	343	2	therapeutic	therapeutic	ADJ
bioscience-271	343	3	practices	practice	NOUN
bioscience-271	343	4	for	for	ADP
bioscience-271	343	5	the	the	DET
bioscience-271	343	6	use	use	NOUN
bioscience-271	343	7	of	of	ADP
bioscience-271	343	8	antibacterial	antibacterial	ADJ
bioscience-271	343	9	agents	agent	NOUN
bioscience-271	343	10	in	in	ADP
bioscience-271	343	11	finfish	finfish	ADJ
bioscience-271	343	12	aquaculture	aquaculture	NOUN
bioscience-271	343	13	:	:	PUNCT
bioscience-271	343	14	a	a	DET
bioscience-271	343	15	particular	particular	ADJ
bioscience-271	343	16	view	view	NOUN
bioscience-271	343	17	on	on	ADP
bioscience-271	343	18	european	european	ADJ
bioscience-271	343	19	seabass	seabass	NOUN
bioscience-271	343	20	(	(	PUNCT
bioscience-271	343	21	dicentrarchus	dicentrarchus	NOUN
bioscience-271	343	22	labrax	labrax	NOUN
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bioscience-271	343	24	and	and	CCONJ
bioscience-271	343	25	gilthead	gilthead	VERB
bioscience-271	343	26	seabream	seabream	NOUN
bioscience-271	343	27	(	(	PUNCT
bioscience-271	343	28	sparus	sparus	NOUN
bioscience-271	343	29	aurata	aurata	PROPN
bioscience-271	343	30	)	)	PUNCT
bioscience-271	343	31	in	in	ADP
bioscience-271	343	32	mediterranean	mediterranean	PROPN
bioscience-271	343	33	aquaculture	aquaculture	NOUN
bioscience-271	343	34	.	.	PUNCT
bioscience-271	344	1	reviews	review	NOUN
bioscience-271	344	2	in	in	ADP
bioscience-271	344	3	aquaculture	aquaculture	NOUN
bioscience-271	344	4	.	.	PUNCT
bioscience-271	345	1	2021;13:1285	2021;13:1285	NUM
bioscience-271	345	2	-	-	SYM
bioscience-271	345	3	323	323	NUM
bioscience-271	345	4	.	.	PUNCT
bioscience-271	346	1	available	available	ADJ
bioscience-271	346	2	from	from	ADP
bioscience-271	346	3	:	:	PUNCT
bioscience-271	346	4	https://doi.org/10.1111/raq.12523	https://doi.org/10.1111/raq.12523	NOUN
bioscience-271	346	5	.	.	PUNCT
bioscience-271	347	1	21	21	NUM
bioscience-271	347	2	.	.	X
bioscience-271	348	1	patel	patel	PROPN
bioscience-271	348	2	jb	jb	PROPN
bioscience-271	348	3	,	,	PUNCT
bioscience-271	348	4	abraham	abraham	PROPN
bioscience-271	348	5	tj	tj	PROPN
bioscience-271	348	6	,	,	PUNCT
bioscience-271	348	7	bardhan	bardhan	ADV
bioscience-271	348	8	a	a	PRON
bioscience-271	348	9	,	,	PUNCT
bioscience-271	348	10	das	das	PROPN
bioscience-271	348	11	r	r	PROPN
bioscience-271	348	12	,	,	PUNCT
bioscience-271	348	13	sen	sen	PROPN
bioscience-271	348	14	a	a	PROPN
bioscience-271	348	15	,	,	PUNCT
bioscience-271	348	16	boda	boda	PROPN
bioscience-271	348	17	s	s	PROPN
bioscience-271	348	18	,	,	PUNCT
bioscience-271	348	19	et	et	PROPN
bioscience-271	348	20	al	al	PROPN
bioscience-271	348	21	.	.	PROPN
bioscience-271	348	22	efficacy	efficacy	PROPN
bioscience-271	348	23	of	of	ADP
bioscience-271	348	24	oxolinic	oxolinic	ADJ
bioscience-271	348	25	acid	acid	NOUN
bioscience-271	348	26	against	against	ADP
bioscience-271	348	27	aeromonas	aeromonas	PROPN
bioscience-271	348	28	hydrophila	hydrophila	PROPN
bioscience-271	348	29	infection	infection	NOUN
bioscience-271	348	30	in	in	ADP
bioscience-271	348	31	nile	nile	PROPN
bioscience-271	348	32	tilapia	tilapia	PROPN
bioscience-271	348	33	(	(	PUNCT
bioscience-271	348	34	oreochromis	oreochromis	PROPN
bioscience-271	348	35	niloticus	niloticus	PROPN
bioscience-271	348	36	)	)	PUNCT
bioscience-271	348	37	juveniles	juvenile	NOUN
bioscience-271	348	38	.	.	PUNCT
bioscience-271	349	1	aquaculture	aquaculture	NOUN
bioscience-271	349	2	studies	study	NOUN
bioscience-271	349	3	.	.	PUNCT
bioscience-271	350	1	2024;24(3):aquast1653	2024;24(3):aquast1653	NUM
bioscience-271	350	2	.	.	PUNCT
bioscience-271	351	1	22	22	NUM
bioscience-271	351	2	.	.	PUNCT
bioscience-271	352	1	sinha	sinha	PROPN
bioscience-271	352	2	p	p	PROPN
bioscience-271	352	3	,	,	PUNCT
bioscience-271	352	4	abraham	abraham	PROPN
bioscience-271	352	5	tj	tj	PROPN
bioscience-271	352	6	,	,	PUNCT
bioscience-271	352	7	sen	sen	PROPN
bioscience-271	352	8	a	a	PROPN
bioscience-271	352	9	,	,	PUNCT
bioscience-271	352	10	sharon	sharon	PROPN
bioscience-271	352	11	j	j	PROPN
bioscience-271	352	12	,	,	PUNCT
bioscience-271	352	13	das	das	PROPN
bioscience-271	352	14	r	r	X
bioscience-271	352	15	,	,	PUNCT
bioscience-271	352	16	ghorai	ghorai	VERB
bioscience-271	352	17	a	a	PRON
bioscience-271	352	18	,	,	PUNCT
bioscience-271	352	19	et	et	PROPN
bioscience-271	352	20	al	al	PROPN
bioscience-271	352	21	.	.	PROPN
bioscience-271	352	22	oxolinic	oxolinic	PROPN
bioscience-271	352	23	acid	acid	PROPN
bioscience-271	352	24	therapy	therapy	NOUN
bioscience-271	352	25	:	:	PUNCT
bioscience-271	352	26	an	an	DET
bioscience-271	352	27	effective	effective	ADJ
bioscience-271	352	28	way	way	NOUN
bioscience-271	352	29	to	to	PART
bioscience-271	352	30	reduce	reduce	VERB
bioscience-271	352	31	aeromonas	aeromonas	PROPN
bioscience-271	352	32	veronii	veronii	ADJ
bioscience-271	352	33	infection	infection	NOUN
bioscience-271	352	34	in	in	ADP
bioscience-271	352	35	oreochromis	oreochromis	PROPN
bioscience-271	352	36	niloticus	niloticus	PROPN
bioscience-271	352	37	and	and	CCONJ
bioscience-271	352	38	improve	improve	VERB
bioscience-271	352	39	biochemical	biochemical	ADJ
bioscience-271	352	40	and	and	CCONJ
bioscience-271	352	41	hematological	hematological	ADJ
bioscience-271	352	42	parameters	parameter	NOUN
bioscience-271	352	43	and	and	CCONJ
bioscience-271	352	44	histopathological	histopathological	ADJ
bioscience-271	352	45	lesions	lesion	NOUN
bioscience-271	352	46	.	.	PUNCT
bioscience-271	353	1	fisheries	fishery	NOUN
bioscience-271	353	2	and	and	CCONJ
bioscience-271	353	3	aquatic	aquatic	ADJ
bioscience-271	353	4	life	life	NOUN
bioscience-271	353	5	.	.	PUNCT
bioscience-271	354	1	2025;33:1	2025;33:1	NUM
bioscience-271	354	2	-	-	SYM
bioscience-271	354	3	18	18	NUM
bioscience-271	354	4	.	.	PUNCT
bioscience-271	354	5	available	available	ADJ
bioscience-271	354	6	from	from	ADP
bioscience-271	354	7	:	:	PUNCT
bioscience-271	354	8	https://doi.org/	https://doi.org/	NOUN
bioscience-271	354	9	10.2478	10.2478	NUM
bioscience-271	354	10	/	/	SYM
bioscience-271	354	11	aopf-2025	aopf-2025	NOUN
bioscience-271	354	12	-	-	PUNCT
bioscience-271	354	13	0001	0001	NUM
bioscience-271	354	14	.	.	PUNCT
bioscience-271	355	1	23	23	NUM
bioscience-271	355	2	.	.	PUNCT
bioscience-271	356	1	abraham	abraham	PROPN
bioscience-271	356	2	tj	tj	PROPN
bioscience-271	356	3	,	,	PUNCT
bioscience-271	356	4	patel	patel	PROPN
bioscience-271	356	5	jb	jb	PROPN
bioscience-271	356	6	,	,	PUNCT
bioscience-271	356	7	bardhan	bardhan	ADV
bioscience-271	356	8	a	a	PRON
bioscience-271	356	9	,	,	PUNCT
bioscience-271	356	10	rajisha	rajisha	NOUN
bioscience-271	356	11	r	r	NOUN
bioscience-271	356	12	,	,	PUNCT
bioscience-271	356	13	panda	panda	NOUN
bioscience-271	356	14	sk	sk	NOUN
bioscience-271	356	15	,	,	PUNCT
bioscience-271	356	16	patil	patil	PROPN
bioscience-271	356	17	pk	pk	PROPN
bioscience-271	356	18	.	.	PROPN
bioscience-271	356	19	safety	safety	NOUN
bioscience-271	356	20	,	,	PUNCT
bioscience-271	356	21	tolerability	tolerability	NOUN
bioscience-271	356	22	,	,	PUNCT
bioscience-271	356	23	and	and	CCONJ
bioscience-271	356	24	biological	biological	ADJ
bioscience-271	356	25	responses	response	NOUN
bioscience-271	356	26	of	of	ADP
bioscience-271	356	27	oreochromis	oreochromis	PROPN
bioscience-271	356	28	niloticus	niloticus	PROPN
bioscience-271	356	29	juveniles	juvenile	NOUN
bioscience-271	356	30	upon	upon	SCONJ
bioscience-271	356	31	oral	oral	ADJ
bioscience-271	356	32	oxolinic	oxolinic	ADJ
bioscience-271	356	33	acid	acid	PROPN
bioscience-271	356	34	administration	administration	PROPN
bioscience-271	356	35	.	.	PUNCT
bioscience-271	357	1	journal	journal	PROPN
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bioscience-271	357	3	veterinary	veterinary	ADJ
bioscience-271	357	4	pharmacology	pharmacology	NOUN
bioscience-271	357	5	and	and	CCONJ
bioscience-271	357	6	therapeutics	therapeutic	NOUN
bioscience-271	357	7	.	.	PUNCT
bioscience-271	358	1	2024;47(2):121	2024;47(2):121	NUM
bioscience-271	358	2	-	-	SYM
bioscience-271	358	3	33	33	NUM
bioscience-271	358	4	.	.	PUNCT
bioscience-271	358	5	available	available	ADJ
bioscience-271	358	6	from	from	ADP
bioscience-271	358	7	:	:	PUNCT
bioscience-271	358	8	https	https	NOUN
bioscience-271	358	9	:	:	PUNCT
bioscience-271	358	10	//doi.org/10.1111	//doi.org/10.1111	PUNCT
bioscience-271	358	11	/	/	SYM
bioscience-271	358	12	jvp.13408	jvp.13408	PROPN
bioscience-271	358	13	.	.	PUNCT
bioscience-271	359	1	highlights	highlight	NOUN
bioscience-271	359	2	in	in	ADP
bioscience-271	359	3	bioscience	bioscience	NOUN
bioscience-271	359	4	page	page	NOUN
bioscience-271	359	5	8	8	NUM
bioscience-271	359	6	of	of	ADP
bioscience-271	359	7	10	10	NUM
bioscience-271	359	8	october	october	PROPN
bioscience-271	359	9	2025|volume	2025|volume	NUM
bioscience-271	359	10	8	8	NUM
bioscience-271	359	11	https://doi.org/10.3390/ani10112166	https://doi.org/10.3390/ani10112166	NOUN
bioscience-271	359	12	https://doi.org/10.3390/ani10112166	https://doi.org/10.3390/ani10112166	PROPN
bioscience-271	359	13	https://doi.org/10.1016/j.aquaculture.2019.734543	https://doi.org/10.1016/j.aquaculture.2019.734543	ADJ
bioscience-271	359	14	https://doi.org/10.1016/j.aquaculture.2019.734543	https://doi.org/10.1016/j.aquaculture.2019.734543	PROPN
bioscience-271	359	15	https://doi.org/10.1016/j.aquaculture.2021.737370	https://doi.org/10.1016/j.aquaculture.2021.737370	ADJ
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bioscience-271	359	17	https://doi.org/10.1002/jemt.23481	https://doi.org/10.1002/jemt.23481	PROPN
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bioscience-271	359	19	https://www.who.int/publications/i/item/9789241515528	https://www.who.int/publications/i/item/9789241515528	PROPN
bioscience-271	359	20	https://www.who.int/publications/i/item/9789241515528	https://www.who.int/publications/i/item/9789241515528	PROPN
bioscience-271	360	1	https://doi.org/10.1111/raq.12344	https://doi.org/10.1111/raq.12344	PROPN
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bioscience-271	360	7	https://cdn.who.int/media/docs/default-source/gcp/who-mia-list-2024-lv.pdf	https://cdn.who.int/media/docs/default-source/gcp/who-mia-list-2024-lv.pdf	PROPN
bioscience-271	360	8	https://cdn.who.int/media/docs/default-source/gcp/who-mia-list-2024-lv.pdf	https://cdn.who.int/media/docs/default-source/gcp/who-mia-list-2024-lv.pdf	PROPN
bioscience-271	360	9	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	PROPN
bioscience-271	360	10	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	PROPN
bioscience-271	360	11	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	PROPN
bioscience-271	360	12	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	https://www.ema.europa.eu/en/documents/committee-report/committee-medicinal-products-veterinary-use-cvmp-monthly-report-application-procedures-guidelines_en-4.pdf	PROPN
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bioscience-271	360	14	https://www.woah.org/app/uploads/2021/03/a-oie-list-antimicrobials-july2019.pdf	https://www.woah.org/app/uploads/2021/03/a-oie-list-antimicrobials-july2019.pdf	PROPN
bioscience-271	360	15	https://www.oie.int/fileadmin/home/eng/	https://www.oie.int/fileadmin/home/eng/	VERB
bioscience-271	360	16	https://www.oie.int/fileadmin/home/eng/	https://www.oie.int/fileadmin/home/eng/	PROPN
bioscience-271	361	1	https://doi.org/10.1016/j.aquaculture.2019.734820	https://doi.org/10.1016/j.aquaculture.2019.734820	PROPN
bioscience-271	361	2	https://doi.org/10.1016/j.aquaculture.2019.734820	https://doi.org/10.1016/j.aquaculture.2019.734820	PROPN
bioscience-271	361	3	https://doi.org/10.1111/raq.12523	https://doi.org/10.1111/raq.12523	PROPN
bioscience-271	361	4	https://doi.org/10.2478/aopf-2025-0001	https://doi.org/10.2478/aopf-2025-0001	PROPN
bioscience-271	362	1	https://doi.org/10.2478/aopf-2025-0001	https://doi.org/10.2478/aopf-2025-0001	PROPN
bioscience-271	363	1	https://doi.org/10.1111/jvp.13408	https://doi.org/10.1111/jvp.13408	ADV
bioscience-271	363	2	https://doi.org/10.1111/jvp.13408	https://doi.org/10.1111/jvp.13408	ADV
bioscience-271	363	3	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
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bioscience-271	363	14	acid	acid	NOUN
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bioscience-271	364	1	abdallah	abdallah	PROPN
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bioscience-271	364	23	tilapia	tilapia	PROPN
bioscience-271	364	24	(	(	PUNCT
bioscience-271	364	25	oreochromis	oreochromis	PROPN
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bioscience-271	364	28	a	a	DET
bioscience-271	364	29	review	review	NOUN
bioscience-271	364	30	.	.	PUNCT
bioscience-271	365	1	biology	biology	NOUN
bioscience-271	365	2	.	.	PUNCT
bioscience-271	366	1	2024;13:914	2024;13:914	X
bioscience-271	366	2	.	.	PUNCT
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bioscience-271	366	4	from	from	ADP
bioscience-271	366	5	:	:	PUNCT
bioscience-271	366	6	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	366	7	.	.	PUNCT
bioscience-271	366	8	3390	3390	NUM
bioscience-271	366	9	/	/	SYM
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bioscience-271	366	11	.	.	PUNCT
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bioscience-271	367	2	.	.	PUNCT
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bioscience-271	367	4	s	s	PROPN
bioscience-271	367	5	,	,	PUNCT
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bioscience-271	367	7	t	t	PROPN
bioscience-271	367	8	,	,	PUNCT
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bioscience-271	367	10	s	s	PROPN
bioscience-271	367	11	,	,	PUNCT
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bioscience-271	367	15	of	of	ADP
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bioscience-271	367	22	streptococcus	streptococcus	NOUN
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bioscience-271	367	24	associated	associate	VERB
bioscience-271	367	25	with	with	ADP
bioscience-271	367	26	bovine	bovine	ADJ
bioscience-271	367	27	mastitis	mastitis	ADJ
bioscience-271	367	28	cases	case	NOUN
bioscience-271	367	29	in	in	ADP
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bioscience-271	367	31	.	.	PUNCT
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bioscience-271	368	2	.	.	PUNCT
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bioscience-271	369	5	:	:	PUNCT
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bioscience-271	369	7	.	.	PUNCT
bioscience-271	369	8	3390	3390	NUM
bioscience-271	369	9	/	/	SYM
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bioscience-271	369	11	.	.	PUNCT
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bioscience-271	370	2	.	.	PUNCT
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bioscience-271	371	3	,	,	PUNCT
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bioscience-271	371	5	ee	ee	PROPN
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bioscience-271	371	7	whiting	white	VERB
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bioscience-271	371	9	,	,	PUNCT
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bioscience-271	371	18	.	.	PUNCT
bioscience-271	372	1	a	a	DET
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bioscience-271	372	3	serine	serine	NOUN
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bioscience-271	372	5	rich	rich	ADJ
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bioscience-271	372	7	protein	protein	NOUN
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bioscience-271	372	9	srr-2	srr-2	X
bioscience-271	372	10	)	)	PUNCT
bioscience-271	372	11	and	and	CCONJ
bioscience-271	372	12	novel	novel	ADJ
bioscience-271	372	13	surface	surface	NOUN
bioscience-271	372	14	antigen	antigen	NOUN
bioscience-271	372	15	(	(	PUNCT
bioscience-271	372	16	epsilon	epsilon	PROPN
bioscience-271	372	17	)	)	PUNCT
bioscience-271	372	18	associated	associate	VERB
bioscience-271	372	19	with	with	ADP
bioscience-271	372	20	a	a	DET
bioscience-271	372	21	virulent	virulent	ADJ
bioscience-271	372	22	lineage	lineage	NOUN
bioscience-271	372	23	of	of	ADP
bioscience-271	372	24	serotype	serotype	ADJ
bioscience-271	372	25	iii	iii	NOUN
bioscience-271	372	26	streptococcus	streptococcus	NOUN
bioscience-271	372	27	agalactiae	agalactiae	NOUN
bioscience-271	372	28	.	.	PUNCT
bioscience-271	373	1	microbiology	microbiology	NOUN
bioscience-271	373	2	.	.	PUNCT
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bioscience-271	374	4	.	.	PUNCT
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bioscience-271	375	3	:	:	PUNCT
bioscience-271	375	4	https://doi.org/10.1099/mic.0.28516-0	https://doi.org/10.1099/mic.0.28516-0	PROPN
bioscience-271	375	5	.	.	PROPN
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bioscience-271	376	2	.	.	PUNCT
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bioscience-271	377	3	,	,	PUNCT
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bioscience-271	377	6	,	,	PUNCT
bioscience-271	377	7	mlia	mlia	PROPN
bioscience-271	377	8	e	e	PROPN
bioscience-271	377	9	,	,	PUNCT
bioscience-271	377	10	nishihara	nishihara	PROPN
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bioscience-271	377	12	,	,	PUNCT
bioscience-271	377	13	chan	chan	PROPN
bioscience-271	377	14	jm	jm	PROPN
bioscience-271	377	15	,	,	PUNCT
bioscience-271	377	16	msefula	msefula	PROPN
bioscience-271	377	17	j	j	PROPN
bioscience-271	377	18	,	,	PUNCT
bioscience-271	377	19	et	et	PROPN
bioscience-271	377	20	al	al	PROPN
bioscience-271	377	21	.	.	PROPN
bioscience-271	377	22	pan	pan	PROPN
bioscience-271	377	23	-	-	PROPN
bioscience-271	377	24	gwas	gwas	NOUN
bioscience-271	377	25	of	of	ADP
bioscience-271	377	26	streptococcus	streptococcus	NOUN
bioscience-271	377	27	agalactiae	agalactiae	ADJ
bioscience-271	377	28	highlights	highlight	NOUN
bioscience-271	377	29	lineage	lineage	NOUN
bioscience-271	377	30	-	-	PUNCT
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bioscience-271	377	35	virulence	virulence	NOUN
bioscience-271	377	36	and	and	CCONJ
bioscience-271	377	37	niche	niche	NOUN
bioscience-271	377	38	adaptation	adaptation	NOUN
bioscience-271	377	39	.	.	PUNCT
bioscience-271	378	1	mbio	mbio	PROPN
bioscience-271	378	2	.	.	PUNCT
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bioscience-271	379	2	-	-	SYM
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bioscience-271	379	4	.	.	PUNCT
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bioscience-271	379	7	:	:	PUNCT
bioscience-271	379	8	https://doi.org/10.1128/mbio.00728-20	https://doi.org/10.1128/mbio.00728-20	PROPN
bioscience-271	379	9	.	.	PUNCT
bioscience-271	380	1	28	28	NUM
bioscience-271	380	2	.	.	PUNCT
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bioscience-271	381	4	the	the	DET
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bioscience-271	381	6	of	of	ADP
bioscience-271	381	7	group	group	NOUN
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bioscience-271	381	10	virulence	virulence	NOUN
bioscience-271	381	11	factors	factor	NOUN
bioscience-271	381	12	.	.	PUNCT
bioscience-271	382	1	future	future	ADJ
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bioscience-271	383	2	-	-	SYM
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bioscience-271	383	4	.	.	PUNCT
bioscience-271	384	1	available	available	ADJ
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bioscience-271	384	3	:	:	PUNCT
bioscience-271	384	4	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	384	5	.	.	PUNCT
bioscience-271	385	1	2217/17460913.4.2.201	2217/17460913.4.2.201	NUM
bioscience-271	385	2	.	.	NOUN
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bioscience-271	385	4	.	.	PUNCT
bioscience-271	386	1	julinta	julinta	PROPN
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bioscience-271	386	3	,	,	PUNCT
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bioscience-271	386	5	tj	tj	PROPN
bioscience-271	386	6	,	,	PUNCT
bioscience-271	386	7	roy	roy	PROPN
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bioscience-271	386	9	,	,	PUNCT
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bioscience-271	386	11	j	j	PROPN
bioscience-271	386	12	,	,	PUNCT
bioscience-271	386	13	dash	dash	VERB
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bioscience-271	386	18	,	,	PUNCT
bioscience-271	386	19	et	et	PROPN
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bioscience-271	386	21	.	.	PROPN
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bioscience-271	386	26	in	in	ADP
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bioscience-271	386	28	-	-	PUNCT
bioscience-271	386	29	treated	treat	VERB
bioscience-271	386	30	oreochromis	oreochromis	PROPN
bioscience-271	386	31	niloticus	niloticus	PROPN
bioscience-271	386	32	(	(	PUNCT
bioscience-271	386	33	l.	l.	PROPN
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bioscience-271	386	37	hydrophila	hydrophila	VERB
bioscience-271	386	38	intramuscular	intramuscular	ADJ
bioscience-271	386	39	challenge	challenge	NOUN
bioscience-271	386	40	.	.	PUNCT
bioscience-271	387	1	journal	journal	NOUN
bioscience-271	387	2	of	of	ADP
bioscience-271	387	3	aquaculture	aquaculture	NOUN
bioscience-271	387	4	research	research	NOUN
bioscience-271	387	5	&	&	CCONJ
bioscience-271	387	6	development	development	NOUN
bioscience-271	387	7	.	.	PUNCT
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bioscience-271	388	2	.	.	PUNCT
bioscience-271	388	3	available	available	ADJ
bioscience-271	388	4	from	from	ADP
bioscience-271	388	5	:	:	PUNCT
bioscience-271	388	6	https://doi.org/	https://doi.org/	NOUN
bioscience-271	388	7	10.4172/2155	10.4172/2155	PROPN
bioscience-271	388	8	-	-	SYM
bioscience-271	388	9	9546.1000488	9546.1000488	NUM
bioscience-271	388	10	.	.	PROPN
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bioscience-271	388	12	.	.	PUNCT
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bioscience-271	389	3	,	,	PUNCT
bioscience-271	389	4	namdeo	namdeo	PROPN
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bioscience-271	389	6	,	,	PUNCT
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bioscience-271	389	8	h	h	NOUN
bioscience-271	389	9	,	,	PUNCT
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bioscience-271	389	18	in	in	ADP
bioscience-271	389	19	challenged	challenge	VERB
bioscience-271	389	20	mozambique	mozambique	ADJ
bioscience-271	389	21	tilapia	tilapia	NOUN
bioscience-271	389	22	oreochromis	oreochromis	PROPN
bioscience-271	389	23	mossambicus	mossambicus	PROPN
bioscience-271	389	24	(	(	PUNCT
bioscience-271	389	25	peters	peters	PROPN
bioscience-271	389	26	1852	1852	NUM
bioscience-271	389	27	)	)	PUNCT
bioscience-271	389	28	juveniles	juvenile	NOUN
bioscience-271	389	29	.	.	PUNCT
bioscience-271	390	1	aquatic	aquatic	ADJ
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bioscience-271	390	3	.	.	PUNCT
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bioscience-271	391	2	-	-	SYM
bioscience-271	391	3	90	90	NUM
bioscience-271	391	4	.	.	PUNCT
bioscience-271	392	1	available	available	ADJ
bioscience-271	392	2	from	from	ADP
bioscience-271	392	3	:	:	PUNCT
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bioscience-271	392	5	.	.	PUNCT
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bioscience-271	392	7	.	.	PUNCT
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bioscience-271	393	3	,	,	PUNCT
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bioscience-271	393	5	h.	h.	PROPN
bioscience-271	394	1	a	a	DET
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bioscience-271	394	4	of	of	ADP
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bioscience-271	394	7	per	per	NOUN
bioscience-271	394	8	cent	cent	NOUN
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bioscience-271	395	2	journal	journal	PROPN
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bioscience-271	395	5	.	.	PUNCT
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bioscience-271	396	4	.	.	PUNCT
bioscience-271	396	5	available	available	ADJ
bioscience-271	396	6	from	from	ADP
bioscience-271	396	7	:	:	PUNCT
bioscience-271	396	8	https://www.cabidigitallibrary.org/doi/	https://www.cabidigitallibrary.org/doi/	PROPN
bioscience-271	396	9	full/10.5555/19412202800	full/10.5555/19412202800	PROPN
bioscience-271	396	10	.	.	PROPN
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bioscience-271	396	12	.	.	PUNCT
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bioscience-271	397	6	.	.	PUNCT
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bioscience-271	398	3	for	for	ADP
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bioscience-271	398	6	testing	testing	NOUN
bioscience-271	398	7	.	.	PUNCT
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bioscience-271	399	3	.	.	PUNCT
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bioscience-271	400	2	,	,	PUNCT
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bioscience-271	400	4	,	,	PUNCT
bioscience-271	400	5	usa	usa	PROPN
bioscience-271	400	6	:	:	PUNCT
bioscience-271	400	7	clsi	clsi	NOUN
bioscience-271	400	8	;	;	PUNCT
bioscience-271	400	9	2012	2012	NUM
bioscience-271	400	10	.	.	PUNCT
bioscience-271	401	1	33	33	NUM
bioscience-271	401	2	.	.	PUNCT
bioscience-271	402	1	roberts	roberts	PROPN
bioscience-271	402	2	rj	rj	PROPN
bioscience-271	402	3	.	.	PROPN
bioscience-271	402	4	fish	fish	PROPN
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bioscience-271	402	6	.	.	PUNCT
bioscience-271	403	1	4th	4th	ADJ
bioscience-271	403	2	ed	ed	NOUN
bioscience-271	403	3	.	.	PUNCT
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bioscience-271	404	5	;	;	PUNCT
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bioscience-271	404	7	.	.	PUNCT
bioscience-271	405	1	34	34	NUM
bioscience-271	405	2	.	.	PUNCT
bioscience-271	405	3	bernet	bernet	PROPN
bioscience-271	405	4	d	d	PROPN
bioscience-271	405	5	,	,	PUNCT
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bioscience-271	405	7	h	h	PROPN
bioscience-271	405	8	,	,	PUNCT
bioscience-271	405	9	meier	meier	PROPN
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bioscience-271	405	11	,	,	PUNCT
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bioscience-271	405	13	-	-	PUNCT
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bioscience-271	405	18	t.	t.	PROPN
bioscience-271	405	19	histopathology	histopathology	NOUN
bioscience-271	405	20	in	in	ADP
bioscience-271	405	21	fish	fish	NOUN
bioscience-271	405	22	:	:	PUNCT
bioscience-271	405	23	proposal	proposal	NOUN
bioscience-271	405	24	for	for	ADP
bioscience-271	405	25	a	a	DET
bioscience-271	405	26	protocol	protocol	NOUN
bioscience-271	405	27	to	to	PART
bioscience-271	405	28	assess	assess	VERB
bioscience-271	405	29	aquatic	aquatic	ADJ
bioscience-271	405	30	pollution	pollution	NOUN
bioscience-271	405	31	.	.	PUNCT
bioscience-271	406	1	journal	journal	PROPN
bioscience-271	406	2	of	of	ADP
bioscience-271	406	3	fish	fish	NOUN
bioscience-271	406	4	diseases	disease	NOUN
bioscience-271	406	5	.	.	PUNCT
bioscience-271	407	1	1999;22(1):2534	1999;22(1):2534	NUM
bioscience-271	407	2	.	.	PUNCT
bioscience-271	407	3	available	available	ADJ
bioscience-271	407	4	from	from	ADP
bioscience-271	407	5	:	:	PUNCT
bioscience-271	407	6	https://doi.org/10.1046/j	https://doi.org/10.1046/j	NOUN
bioscience-271	407	7	.	.	PUNCT
bioscience-271	408	1	1365	1365	NUM
bioscience-271	408	2	-	-	SYM
bioscience-271	408	3	2761.1999.00134.x	2761.1999.00134.x	NUM
bioscience-271	408	4	.	.	PROPN
bioscience-271	408	5	35	35	NUM
bioscience-271	408	6	.	.	PUNCT
bioscience-271	409	1	morris	morris	PROPN
bioscience-271	409	2	gm	gm	PROPN
bioscience-271	409	3	,	,	PUNCT
bioscience-271	409	4	huey	huey	PROPN
bioscience-271	409	5	r	r	PROPN
bioscience-271	409	6	,	,	PUNCT
bioscience-271	409	7	lindstrom	lindstrom	PROPN
bioscience-271	409	8	w	w	PROPN
bioscience-271	409	9	,	,	PUNCT
bioscience-271	409	10	sanner	sanner	NOUN
bioscience-271	409	11	mf	mf	PROPN
bioscience-271	409	12	,	,	PUNCT
bioscience-271	409	13	belew	belew	NOUN
bioscience-271	409	14	rk	rk	PROPN
bioscience-271	409	15	,	,	PUNCT
bioscience-271	409	16	goodsell	goodsell	X
bioscience-271	409	17	ds	ds	PROPN
bioscience-271	409	18	,	,	PUNCT
bioscience-271	409	19	et	et	PROPN
bioscience-271	409	20	al	al	PROPN
bioscience-271	409	21	.	.	PUNCT
bioscience-271	410	1	autodock4	autodock4	PROPN
bioscience-271	410	2	and	and	CCONJ
bioscience-271	410	3	autodocktools4	autodocktools4	NOUN
bioscience-271	410	4	:	:	PUNCT
bioscience-271	410	5	automated	automate	VERB
bioscience-271	410	6	docking	docking	NOUN
bioscience-271	410	7	with	with	ADP
bioscience-271	410	8	selective	selective	ADJ
bioscience-271	410	9	receptor	receptor	NOUN
bioscience-271	410	10	flexibility	flexibility	NOUN
bioscience-271	410	11	.	.	PUNCT
bioscience-271	411	1	journal	journal	NOUN
bioscience-271	411	2	of	of	ADP
bioscience-271	411	3	computational	computational	ADJ
bioscience-271	411	4	chemistry	chemistry	NOUN
bioscience-271	411	5	.	.	PUNCT
bioscience-271	412	1	2009;30(16):2785	2009;30(16):2785	NUM
bioscience-271	412	2	-	-	SYM
bioscience-271	412	3	91	91	NUM
bioscience-271	412	4	.	.	PUNCT
bioscience-271	413	1	available	available	ADJ
bioscience-271	413	2	from	from	ADP
bioscience-271	413	3	:	:	PUNCT
bioscience-271	413	4	https://doi.org/10.1002/jcc.21256	https://doi.org/10.1002/jcc.21256	PROPN
bioscience-271	413	5	.	.	PUNCT
bioscience-271	413	6	36	36	NUM
bioscience-271	413	7	.	.	PUNCT
bioscience-271	414	1	jeffrey	jeffrey	PROPN
bioscience-271	414	2	ga	ga	PROPN
bioscience-271	414	3	.	.	PUNCT
bioscience-271	415	1	an	an	DET
bioscience-271	415	2	introduction	introduction	NOUN
bioscience-271	415	3	to	to	ADP
bioscience-271	415	4	hydrogen	hydrogen	NOUN
bioscience-271	415	5	bonding	bonding	NOUN
bioscience-271	415	6	.	.	PUNCT
bioscience-271	416	1	oxford	oxford	PROPN
bioscience-271	416	2	university	university	PROPN
bioscience-271	416	3	press	press	NOUN
bioscience-271	416	4	;	;	PUNCT
bioscience-271	416	5	1997	1997	NUM
bioscience-271	416	6	.	.	PUNCT
bioscience-271	417	1	37	37	NUM
bioscience-271	417	2	.	.	X
bioscience-271	417	3	santos	santos	PROPN
bioscience-271	417	4	y	y	PROPN
bioscience-271	417	5	,	,	PUNCT
bioscience-271	417	6	toranzo	toranzo	PROPN
bioscience-271	417	7	ae	ae	PROPN
bioscience-271	417	8	,	,	PUNCT
bioscience-271	417	9	barja	barja	PROPN
bioscience-271	417	10	jl	jl	PROPN
bioscience-271	417	11	,	,	PUNCT
bioscience-271	417	12	nieto	nieto	PROPN
bioscience-271	417	13	tp	tp	PROPN
bioscience-271	417	14	,	,	PUNCT
bioscience-271	417	15	villa	villa	PROPN
bioscience-271	417	16	tg	tg	PROPN
bioscience-271	417	17	.	.	PUNCT
bioscience-271	418	1	virulence	virulence	NOUN
bioscience-271	418	2	properties	property	NOUN
bioscience-271	418	3	and	and	CCONJ
bioscience-271	418	4	enterotoxin	enterotoxin	X
bioscience-271	418	5	production	production	NOUN
bioscience-271	418	6	of	of	ADP
bioscience-271	418	7	aeromonas	aeromonas	PROPN
bioscience-271	418	8	strains	strain	VERB
bioscience-271	418	9	isolated	isolate	VERB
bioscience-271	418	10	from	from	ADP
bioscience-271	418	11	fish	fish	NOUN
bioscience-271	418	12	.	.	PUNCT
bioscience-271	419	1	infection	infection	NOUN
bioscience-271	419	2	and	and	CCONJ
bioscience-271	419	3	immunity	immunity	NOUN
bioscience-271	419	4	.	.	PUNCT
bioscience-271	420	1	1988;56:3285	1988;56:3285	NUM
bioscience-271	420	2	-	-	SYM
bioscience-271	420	3	93	93	NUM
bioscience-271	420	4	.	.	PUNCT
bioscience-271	421	1	available	available	ADJ
bioscience-271	421	2	from	from	ADP
bioscience-271	421	3	:	:	PUNCT
bioscience-271	421	4	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	421	5	.	.	PUNCT
bioscience-271	421	6	1128	1128	NUM
bioscience-271	421	7	/	/	SYM
bioscience-271	421	8	iai.56.12.3285	iai.56.12.3285	PROPN
bioscience-271	421	9	-	-	PUNCT
bioscience-271	421	10	3293.1988	3293.1988	NUM
bioscience-271	421	11	.	.	PUNCT
bioscience-271	422	1	38	38	NUM
bioscience-271	422	2	.	.	PUNCT
bioscience-271	423	1	kayansamruaj	kayansamruaj	PROPN
bioscience-271	423	2	p	p	PROPN
bioscience-271	423	3	,	,	PUNCT
bioscience-271	423	4	pirarat	pirarat	NOUN
bioscience-271	423	5	n	n	PRON
bioscience-271	423	6	,	,	PUNCT
bioscience-271	423	7	katagiri	katagiri	PROPN
bioscience-271	423	8	t	t	PROPN
bioscience-271	423	9	,	,	PUNCT
bioscience-271	423	10	hirono	hirono	PROPN
bioscience-271	423	11	i	i	PROPN
bioscience-271	423	12	,	,	PUNCT
bioscience-271	423	13	rodkhum	rodkhum	PROPN
bioscience-271	423	14	c.	c.	PROPN
bioscience-271	423	15	molecular	molecular	ADJ
bioscience-271	423	16	characterization	characterization	NOUN
bioscience-271	423	17	and	and	CCONJ
bioscience-271	423	18	virulence	virulence	NOUN
bioscience-271	423	19	gene	gene	NOUN
bioscience-271	423	20	profiling	profiling	NOUN
bioscience-271	423	21	of	of	ADP
bioscience-271	423	22	pathogenic	pathogenic	ADJ
bioscience-271	423	23	streptococcus	streptococcus	NOUN
bioscience-271	423	24	agalactiae	agalactiae	ADJ
bioscience-271	423	25	populations	population	NOUN
bioscience-271	423	26	from	from	ADP
bioscience-271	423	27	tilapia	tilapia	NOUN
bioscience-271	423	28	(	(	PUNCT
bioscience-271	423	29	oreochromis	oreochromis	NOUN
bioscience-271	423	30	sp	sp	NOUN
bioscience-271	423	31	.	.	PUNCT
bioscience-271	423	32	)	)	PUNCT
bioscience-271	423	33	farms	farm	NOUN
bioscience-271	423	34	in	in	ADP
bioscience-271	423	35	thailand	thailand	PROPN
bioscience-271	423	36	.	.	PUNCT
bioscience-271	424	1	journal	journal	PROPN
bioscience-271	424	2	of	of	ADP
bioscience-271	424	3	veterinary	veterinary	ADJ
bioscience-271	424	4	diagnostic	diagnostic	ADJ
bioscience-271	424	5	investigation	investigation	NOUN
bioscience-271	424	6	.	.	PUNCT
bioscience-271	425	1	2014;26(4):488	2014;26(4):488	NUM
bioscience-271	425	2	-	-	SYM
bioscience-271	425	3	95	95	NUM
bioscience-271	425	4	.	.	PUNCT
bioscience-271	425	5	available	available	ADJ
bioscience-271	425	6	from	from	ADP
bioscience-271	425	7	:	:	PUNCT
bioscience-271	425	8	https://doi.org/	https://doi.org/	NOUN
bioscience-271	425	9	10.1177/1040638714534237	10.1177/1040638714534237	NUM
bioscience-271	425	10	.	.	NOUN
bioscience-271	425	11	39	39	NUM
bioscience-271	425	12	.	.	PUNCT
bioscience-271	426	1	li	li	PROPN
bioscience-271	426	2	s	s	PROPN
bioscience-271	426	3	,	,	PUNCT
bioscience-271	426	4	li	li	PROPN
bioscience-271	426	5	q	q	PROPN
bioscience-271	426	6	,	,	PUNCT
bioscience-271	426	7	liang	liang	PROPN
bioscience-271	426	8	j	j	PROPN
bioscience-271	426	9	,	,	PUNCT
bioscience-271	426	10	cao	cao	PROPN
bioscience-271	426	11	h	h	PROPN
bioscience-271	426	12	,	,	PUNCT
bioscience-271	426	13	li	li	PROPN
bioscience-271	426	14	z	z	PROPN
bioscience-271	426	15	,	,	PUNCT
bioscience-271	426	16	li	li	PROPN
bioscience-271	426	17	a.	a.	NOUN
bioscience-271	426	18	characterization	characterization	NOUN
bioscience-271	426	19	and	and	CCONJ
bioscience-271	426	20	virulence	virulence	NOUN
bioscience-271	426	21	of	of	ADP
bioscience-271	426	22	streptococcus	streptococcus	ADJ
bioscience-271	426	23	agalactiae	agalactiae	PROPN
bioscience-271	426	24	deficient	deficient	ADJ
bioscience-271	426	25	in	in	ADP
bioscience-271	426	26	saers	saer	NOUN
bioscience-271	426	27	of	of	ADP
bioscience-271	426	28	the	the	DET
bioscience-271	426	29	two	two	NUM
bioscience-271	426	30	-	-	PUNCT
bioscience-271	426	31	component	component	NOUN
bioscience-271	426	32	system	system	NOUN
bioscience-271	426	33	.	.	PUNCT
bioscience-271	427	1	frontiers	frontier	NOUN
bioscience-271	427	2	in	in	ADP
bioscience-271	427	3	microbiology	microbiology	NOUN
bioscience-271	427	4	.	.	PUNCT
bioscience-271	428	1	2023;14:1121621	2023;14:1121621	NUM
bioscience-271	428	2	.	.	PUNCT
bioscience-271	428	3	available	available	ADJ
bioscience-271	428	4	from	from	ADP
bioscience-271	428	5	:	:	PUNCT
bioscience-271	428	6	https://doi.org/10	https://doi.org/10	PROPN
bioscience-271	428	7	.	.	PUNCT
bioscience-271	429	1	3389	3389	NUM
bioscience-271	429	2	/	/	SYM
bioscience-271	429	3	fmicb.2023.1121621	fmicb.2023.1121621	PROPN
bioscience-271	429	4	.	.	PROPN
bioscience-271	429	5	40	40	NUM
bioscience-271	429	6	.	.	PUNCT
bioscience-271	430	1	uematsu	uematsu	PROPN
bioscience-271	430	2	k	k	PROPN
bioscience-271	430	3	,	,	PUNCT
bioscience-271	430	4	baba	baba	PROPN
bioscience-271	430	5	y	y	PROPN
bioscience-271	430	6	,	,	PUNCT
bioscience-271	430	7	kake	kake	PROPN
bioscience-271	430	8	y	y	PROPN
bioscience-271	430	9	,	,	PUNCT
bioscience-271	430	10	ikenaga	ikenaga	PROPN
bioscience-271	430	11	t	t	PROPN
bioscience-271	430	12	,	,	PUNCT
bioscience-271	430	13	moon	moon	NOUN
bioscience-271	430	14	sj	sj	PROPN
bioscience-271	430	15	,	,	PUNCT
bioscience-271	430	16	miyai	miyai	PROPN
bioscience-271	430	17	y	y	PROPN
bioscience-271	430	18	,	,	PUNCT
bioscience-271	430	19	et	et	PROPN
bioscience-271	430	20	al	al	PROPN
bioscience-271	430	21	.	.	PUNCT
bioscience-271	431	1	central	central	ADJ
bioscience-271	431	2	mechanisms	mechanism	NOUN
bioscience-271	431	3	underlying	underlie	VERB
bioscience-271	431	4	fish	fish	NOUN
bioscience-271	431	5	swimming	swimming	NOUN
bioscience-271	431	6	.	.	PUNCT
bioscience-271	432	1	brain	brain	NOUN
bioscience-271	432	2	,	,	PUNCT
bioscience-271	432	3	behavior	behavior	NOUN
bioscience-271	432	4	and	and	CCONJ
bioscience-271	432	5	evolution	evolution	NOUN
bioscience-271	432	6	.	.	PUNCT
bioscience-271	433	1	2007;69(2):142	2007;69(2):142	PROPN
bioscience-271	433	2	-	-	PUNCT
bioscience-271	433	3	50	50	NUM
bioscience-271	433	4	.	.	PUNCT
bioscience-271	433	5	available	available	ADJ
bioscience-271	433	6	from	from	ADP
bioscience-271	433	7	:	:	PUNCT
bioscience-271	433	8	https://doi.org/10.1159/000095203	https://doi.org/10.1159/000095203	PROPN
bioscience-271	433	9	.	.	X
bioscience-271	434	1	41	41	NUM
bioscience-271	434	2	.	.	PUNCT
bioscience-271	435	1	le	le	PROPN
bioscience-271	435	2	guennec	guennec	PROPN
bioscience-271	435	3	l	l	PROPN
bioscience-271	435	4	,	,	PUNCT
bioscience-271	435	5	coureuil	coureuil	PROPN
bioscience-271	435	6	m	m	PROPN
bioscience-271	435	7	,	,	PUNCT
bioscience-271	435	8	nassif	nassif	NOUN
bioscience-271	435	9	x	x	NOUN
bioscience-271	435	10	,	,	PUNCT
bioscience-271	435	11	bourdoulous	bourdoulous	ADJ
bioscience-271	435	12	s.	s.	PROPN
bioscience-271	435	13	strategies	strategy	NOUN
bioscience-271	435	14	used	use	VERB
bioscience-271	435	15	by	by	ADP
bioscience-271	435	16	bacterial	bacterial	ADJ
bioscience-271	435	17	pathogens	pathogen	NOUN
bioscience-271	435	18	to	to	PART
bioscience-271	435	19	cross	cross	VERB
bioscience-271	435	20	the	the	DET
bioscience-271	435	21	bloodbrain	bloodbrain	NOUN
bioscience-271	435	22	barrier	barrier	NOUN
bioscience-271	435	23	.	.	PUNCT
bioscience-271	436	1	cellular	cellular	ADJ
bioscience-271	436	2	microbiology	microbiology	NOUN
bioscience-271	436	3	.	.	PUNCT
bioscience-271	437	1	2020;22(1):e13132	2020;22(1):e13132	X
bioscience-271	437	2	.	.	X
bioscience-271	438	1	42	42	NUM
bioscience-271	438	2	.	.	PUNCT
bioscience-271	439	1	su	su	PROPN
bioscience-271	439	2	yl	yl	PROPN
bioscience-271	439	3	,	,	PUNCT
bioscience-271	439	4	feng	feng	PROPN
bioscience-271	439	5	j	j	PROPN
bioscience-271	439	6	,	,	PUNCT
bioscience-271	439	7	li	li	PROPN
bioscience-271	439	8	yw	yw	PROPN
bioscience-271	439	9	,	,	PUNCT
bioscience-271	439	10	bai	bai	PROPN
bioscience-271	439	11	js	js	PROPN
bioscience-271	439	12	,	,	PUNCT
bioscience-271	439	13	li	li	PROPN
bioscience-271	439	14	ax	ax	PROPN
bioscience-271	439	15	.	.	PUNCT
bioscience-271	440	1	development	development	NOUN
bioscience-271	440	2	of	of	ADP
bioscience-271	440	3	a	a	DET
bioscience-271	440	4	quantitative	quantitative	ADJ
bioscience-271	440	5	pcr	pcr	NOUN
bioscience-271	440	6	assay	assay	NOUN
bioscience-271	440	7	for	for	ADP
bioscience-271	440	8	monitoring	monitor	VERB
bioscience-271	440	9	streptococcus	streptococcus	VERB
bioscience-271	440	10	agalactiae	agalactiae	ADJ
bioscience-271	440	11	colonization	colonization	NOUN
bioscience-271	440	12	and	and	CCONJ
bioscience-271	440	13	tissue	tissue	NOUN
bioscience-271	440	14	tropism	tropism	NOUN
bioscience-271	440	15	in	in	ADP
bioscience-271	440	16	experimentally	experimentally	ADV
bioscience-271	440	17	infected	infect	VERB
bioscience-271	440	18	tilapia	tilapia	NOUN
bioscience-271	440	19	.	.	PUNCT
bioscience-271	441	1	journal	journal	PROPN
bioscience-271	441	2	of	of	ADP
bioscience-271	441	3	fish	fish	NOUN
bioscience-271	441	4	diseases	disease	NOUN
bioscience-271	441	5	.	.	PUNCT
bioscience-271	442	1	2016;39(2):229	2016;39(2):229	NUM
bioscience-271	442	2	-	-	SYM
bioscience-271	442	3	38	38	NUM
bioscience-271	442	4	.	.	PUNCT
bioscience-271	443	1	43	43	NUM
bioscience-271	443	2	.	.	PUNCT
bioscience-271	444	1	isiaku	isiaku	NOUN
bioscience-271	444	2	ai	ai	VERB
bioscience-271	444	3	,	,	PUNCT
bioscience-271	444	4	sabri	sabri	PROPN
bioscience-271	444	5	my	my	PRON
bioscience-271	444	6	,	,	PUNCT
bioscience-271	444	7	ina	ina	PROPN
bioscience-271	444	8	-	-	PUNCT
bioscience-271	444	9	salwany	salwany	NOUN
bioscience-271	444	10	my	my	PRON
bioscience-271	444	11	,	,	PUNCT
bioscience-271	444	12	hassan	hassan	PROPN
bioscience-271	444	13	md	md	PROPN
bioscience-271	444	14	,	,	PUNCT
bioscience-271	444	15	tanko	tanko	PROPN
bioscience-271	444	16	pn	pn	PROPN
bioscience-271	444	17	,	,	PUNCT
bioscience-271	444	18	bello	bello	PROPN
bioscience-271	444	19	mb	mb	NOUN
bioscience-271	444	20	.	.	PUNCT
bioscience-271	444	21	biofilm	biofilm	NOUN
bioscience-271	444	22	is	be	AUX
bioscience-271	444	23	associated	associate	VERB
bioscience-271	444	24	with	with	ADP
bioscience-271	444	25	chronic	chronic	ADJ
bioscience-271	444	26	streptococcal	streptococcal	ADJ
bioscience-271	444	27	meningoencephalitis	meningoencephalitis	NOUN
bioscience-271	444	28	in	in	ADP
bioscience-271	444	29	fish	fish	NOUN
bioscience-271	444	30	.	.	PUNCT
bioscience-271	445	1	microbial	microbial	ADJ
bioscience-271	445	2	pathogenesis	pathogenesis	NOUN
bioscience-271	445	3	.	.	PUNCT
bioscience-271	446	1	2017;102:59	2017;102:59	NUM
bioscience-271	446	2	-	-	SYM
bioscience-271	446	3	68	68	NUM
bioscience-271	446	4	.	.	PUNCT
bioscience-271	447	1	44	44	NUM
bioscience-271	447	2	.	.	PUNCT
bioscience-271	448	1	guo	guo	PROPN
bioscience-271	448	2	cm	cm	PROPN
bioscience-271	448	3	,	,	PUNCT
bioscience-271	448	4	chen	chen	PROPN
bioscience-271	448	5	rr	rr	PROPN
bioscience-271	448	6	,	,	PUNCT
bioscience-271	448	7	kalhoro	kalhoro	PROPN
bioscience-271	448	8	dh	dh	PROPN
bioscience-271	448	9	,	,	PUNCT
bioscience-271	448	10	wang	wang	PROPN
bioscience-271	448	11	zf	zf	PROPN
bioscience-271	448	12	,	,	PUNCT
bioscience-271	448	13	liu	liu	PROPN
bioscience-271	448	14	gj	gj	PROPN
bioscience-271	448	15	,	,	PUNCT
bioscience-271	448	16	lu	lu	PROPN
bioscience-271	448	17	cp	cp	PROPN
bioscience-271	448	18	,	,	PUNCT
bioscience-271	448	19	et	et	PROPN
bioscience-271	448	20	al	al	PROPN
bioscience-271	448	21	.	.	PUNCT
bioscience-271	449	1	identification	identification	NOUN
bioscience-271	449	2	of	of	ADP
bioscience-271	449	3	genes	gene	NOUN
bioscience-271	449	4	preferentially	preferentially	ADV
bioscience-271	449	5	expressed	express	VERB
bioscience-271	449	6	by	by	ADP
bioscience-271	449	7	highly	highly	ADV
bioscience-271	449	8	virulent	virulent	ADJ
bioscience-271	449	9	piscine	piscine	NOUN
bioscience-271	449	10	streptococcus	streptococcus	NOUN
bioscience-271	449	11	agalactiae	agalactiae	NOUN
bioscience-271	449	12	upon	upon	SCONJ
bioscience-271	449	13	interaction	interaction	NOUN
bioscience-271	449	14	with	with	ADP
bioscience-271	449	15	macrophages	macrophage	NOUN
bioscience-271	449	16	.	.	PUNCT
bioscience-271	450	1	plos	plos	PROPN
bioscience-271	450	2	one	one	NUM
bioscience-271	450	3	.	.	PUNCT
bioscience-271	451	1	2014;9(2):e87980	2014;9(2):e87980	X
bioscience-271	451	2	.	.	PUNCT
bioscience-271	452	1	highlights	highlight	NOUN
bioscience-271	452	2	in	in	ADP
bioscience-271	452	3	bioscience	bioscience	NOUN
bioscience-271	452	4	page	page	NOUN
bioscience-271	452	5	9	9	NUM
bioscience-271	452	6	of	of	ADP
bioscience-271	452	7	10	10	NUM
bioscience-271	452	8	october	october	PROPN
bioscience-271	452	9	2025|volume	2025|volume	NUM
bioscience-271	452	10	8	8	NUM
bioscience-271	452	11	https://doi.org/10.3390/biology13110914	https://doi.org/10.3390/biology13110914	PROPN
bioscience-271	452	12	https://doi.org/10.3390/biology13110914	https://doi.org/10.3390/biology13110914	PROPN
bioscience-271	452	13	https://doi.org/10.3390/ani14030447	https://doi.org/10.3390/ani14030447	PROPN
bioscience-271	452	14	https://doi.org/10.3390/ani14030447	https://doi.org/10.3390/ani14030447	PROPN
bioscience-271	452	15	https://doi.org/10.1099/mic.0.28516-0	https://doi.org/10.1099/mic.0.28516-0	PROPN
bioscience-271	452	16	https://doi.org/10.1128/mbio.00728-20	https://doi.org/10.1128/mbio.00728-20	PROPN
bioscience-271	452	17	https://doi.org/10.2217/17460913.4.2.201	https://doi.org/10.2217/17460913.4.2.201	VERB
bioscience-271	452	18	https://doi.org/10.2217/17460913.4.2.201	https://doi.org/10.2217/17460913.4.2.201	VERB
bioscience-271	452	19	https://doi.org/10.4172/2155-9546.1000488	https://doi.org/10.4172/2155-9546.1000488	PROPN
bioscience-271	452	20	https://doi.org/10.4172/2155-9546.1000488	https://doi.org/10.4172/2155-9546.1000488	PROPN
bioscience-271	452	21	https://doi.org/10.3153/ar19017	https://doi.org/10.3153/ar19017	ADP
bioscience-271	452	22	https://www.cabidigitallibrary.org/doi/full/10.5555/19412202800	https://www.cabidigitallibrary.org/doi/full/10.5555/19412202800	PROPN
bioscience-271	452	23	https://www.cabidigitallibrary.org/doi/full/10.5555/19412202800	https://www.cabidigitallibrary.org/doi/full/10.5555/19412202800	PROPN
bioscience-271	452	24	https://doi.org/10.1046/j.1365-2761.1999.00134.x	https://doi.org/10.1046/j.1365-2761.1999.00134.x	NUM
bioscience-271	452	25	https://doi.org/10.1046/j.1365-2761.1999.00134.x	https://doi.org/10.1046/j.1365-2761.1999.00134.x	NUM
bioscience-271	453	1	https://doi.org/10.1002/jcc.21256	https://doi.org/10.1002/jcc.21256	PROPN
bioscience-271	453	2	https://doi.org/10.1128/iai.56.12.3285-3293.1988	https://doi.org/10.1128/iai.56.12.3285-3293.1988	PROPN
bioscience-271	454	1	https://doi.org/10.1128/iai.56.12.3285-3293.1988	https://doi.org/10.1128/iai.56.12.3285-3293.1988	PROPN
bioscience-271	455	1	https://doi.org/10.1177/1040638714534237	https://doi.org/10.1177/1040638714534237	PROPN
bioscience-271	456	1	https://doi.org/10.1177/1040638714534237	https://doi.org/10.1177/1040638714534237	PROPN
bioscience-271	457	1	https://doi.org/10.3389/fmicb.2023.1121621	https://doi.org/10.3389/fmicb.2023.1121621	PROPN
bioscience-271	458	1	https://doi.org/10.3389/fmicb.2023.1121621	https://doi.org/10.3389/fmicb.2023.1121621	PROPN
bioscience-271	458	2	https://doi.org/10.1159/000095203	https://doi.org/10.1159/000095203	PROPN
bioscience-271	458	3	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PROPN
bioscience-271	458	4	sinha	sinha	NOUN
bioscience-271	458	5	p	p	PROPN
bioscience-271	458	6	et	et	PROPN
bioscience-271	458	7	al	al	PROPN
bioscience-271	458	8	.	.	PROPN
bioscience-271	458	9	,	,	PUNCT
bioscience-271	458	10	2025	2025	NUM
bioscience-271	458	11	effect	effect	NOUN
bioscience-271	458	12	of	of	ADP
bioscience-271	458	13	oxolinic	oxolinic	ADJ
bioscience-271	458	14	acid	acid	NOUN
bioscience-271	458	15	therapy	therapy	NOUN
bioscience-271	458	16	45	45	NUM
bioscience-271	458	17	.	.	PUNCT
bioscience-271	459	1	baldissera	baldissera	PROPN
bioscience-271	459	2	md	md	PROPN
bioscience-271	459	3	,	,	PUNCT
bioscience-271	459	4	souza	souza	PROPN
bioscience-271	459	5	cf	cf	PROPN
bioscience-271	459	6	,	,	PUNCT
bioscience-271	459	7	parmeggiani	parmeggiani	ADJ
bioscience-271	459	8	bs	bs	NOUN
bioscience-271	459	9	,	,	PUNCT
bioscience-271	459	10	santos	santos	PROPN
bioscience-271	459	11	rc	rc	PROPN
bioscience-271	459	12	,	,	PUNCT
bioscience-271	459	13	leipnitz	leipnitz	PROPN
bioscience-271	459	14	g	g	PROPN
bioscience-271	459	15	,	,	PUNCT
bioscience-271	459	16	moreira	moreira	PROPN
bioscience-271	459	17	kl	kl	PROPN
bioscience-271	459	18	,	,	PUNCT
bioscience-271	459	19	et	et	PROPN
bioscience-271	459	20	al	al	PROPN
bioscience-271	459	21	.	.	PROPN
bioscience-271	459	22	streptococcus	streptococcus	NOUN
bioscience-271	459	23	agalactiae	agalactiae	PROPN
bioscience-271	459	24	impairs	impair	VERB
bioscience-271	459	25	cerebral	cerebral	ADJ
bioscience-271	459	26	bioenergetics	bioenergetic	NOUN
bioscience-271	459	27	in	in	ADP
bioscience-271	459	28	experimentally	experimentally	ADV
bioscience-271	459	29	infected	infect	VERB
bioscience-271	459	30	silver	silver	ADJ
bioscience-271	459	31	catfish	catfish	NOUN
bioscience-271	459	32	.	.	PUNCT
bioscience-271	460	1	microbial	microbial	ADJ
bioscience-271	460	2	pathogenesis	pathogenesis	NOUN
bioscience-271	460	3	.	.	PUNCT
bioscience-271	461	1	2017;111:28	2017;111:28	NUM
bioscience-271	461	2	-	-	SYM
bioscience-271	461	3	32	32	NUM
bioscience-271	461	4	.	.	PUNCT
bioscience-271	462	1	46	46	NUM
bioscience-271	462	2	.	.	PUNCT
bioscience-271	462	3	de	de	PROPN
bioscience-271	462	4	sousa	sousa	PROPN
bioscience-271	462	5	el	el	PROPN
bioscience-271	462	6	,	,	PUNCT
bioscience-271	462	7	assane	assane	PROPN
bioscience-271	462	8	i	i	PROPN
bioscience-271	462	9	m	m	PROPN
bioscience-271	462	10	,	,	PUNCT
bioscience-271	462	11	santos	santos	PROPN
bioscience-271	462	12	-	-	PUNCT
bioscience-271	462	13	filho	filho	PROPN
bioscience-271	462	14	na	na	NOUN
bioscience-271	462	15	,	,	PUNCT
bioscience-271	462	16	cilli	cilli	VERB
bioscience-271	462	17	em	em	PRON
bioscience-271	462	18	,	,	PUNCT
bioscience-271	462	19	de	de	PROPN
bioscience-271	462	20	jesus	jesus	PROPN
bioscience-271	462	21	rb	rb	PROPN
bioscience-271	462	22	,	,	PUNCT
bioscience-271	462	23	pilarski	pilarski	PROPN
bioscience-271	462	24	f.	f.	PROPN
bioscience-271	462	25	haematological	haematological	PROPN
bioscience-271	462	26	,	,	PUNCT
bioscience-271	462	27	biochemical	biochemical	ADJ
bioscience-271	462	28	,	,	PUNCT
bioscience-271	462	29	and	and	CCONJ
bioscience-271	462	30	immunological	immunological	ADJ
bioscience-271	462	31	biomarkers	biomarker	NOUN
bioscience-271	462	32	,	,	PUNCT
bioscience-271	462	33	antibacterial	antibacterial	ADJ
bioscience-271	462	34	activity	activity	NOUN
bioscience-271	462	35	,	,	PUNCT
bioscience-271	462	36	and	and	CCONJ
bioscience-271	462	37	survival	survival	NOUN
bioscience-271	462	38	in	in	ADP
bioscience-271	462	39	nile	nile	PROPN
bioscience-271	462	40	tilapia	tilapia	PROPN
bioscience-271	462	41	oreochromis	oreochromis	PROPN
bioscience-271	462	42	niloticus	niloticus	PROPN
bioscience-271	462	43	after	after	ADP
bioscience-271	462	44	treatment	treatment	NOUN
bioscience-271	462	45	using	use	VERB
bioscience-271	462	46	antimicrobial	antimicrobial	ADJ
bioscience-271	462	47	peptide	peptide	NOUN
bioscience-271	462	48	ll-37	ll-37	NOUN
bioscience-271	462	49	against	against	ADP
bioscience-271	462	50	streptococcus	streptococcus	NOUN
bioscience-271	462	51	agalactiae	agalactiae	NOUN
bioscience-271	462	52	.	.	PUNCT
bioscience-271	463	1	aquaculture	aquaculture	PROPN
bioscience-271	463	2	.	.	PUNCT
bioscience-271	464	1	2021;533:736181	2021;533:736181	NUM
bioscience-271	464	2	.	.	PUNCT
bioscience-271	465	1	47	47	NUM
bioscience-271	465	2	.	.	PUNCT
bioscience-271	465	3	barichello	barichello	PROPN
bioscience-271	465	4	t	t	PROPN
bioscience-271	465	5	,	,	PUNCT
bioscience-271	465	6	lemos	lemos	PROPN
bioscience-271	465	7	jc	jc	PROPN
bioscience-271	465	8	,	,	PUNCT
bioscience-271	465	9	generoso	generoso	PROPN
bioscience-271	465	10	js	js	PROPN
bioscience-271	465	11	,	,	PUNCT
bioscience-271	465	12	cipriano	cipriano	PROPN
bioscience-271	465	13	al	al	PROPN
bioscience-271	465	14	,	,	PUNCT
bioscience-271	465	15	milioli	milioli	PROPN
bioscience-271	465	16	gl	gl	PROPN
bioscience-271	465	17	,	,	PUNCT
bioscience-271	465	18	marcelino	marcelino	PROPN
bioscience-271	465	19	dm	dm	PROPN
bioscience-271	465	20	,	,	PUNCT
bioscience-271	465	21	et	et	PROPN
bioscience-271	465	22	al	al	PROPN
bioscience-271	465	23	.	.	PROPN
bioscience-271	465	24	oxidative	oxidative	ADJ
bioscience-271	465	25	stress	stress	NOUN
bioscience-271	465	26	,	,	PUNCT
bioscience-271	465	27	cytokine	cytokine	NOUN
bioscience-271	465	28	/	/	SYM
bioscience-271	465	29	chemokine	chemokine	ADJ
bioscience-271	465	30	and	and	CCONJ
bioscience-271	465	31	disruption	disruption	NOUN
bioscience-271	465	32	of	of	ADP
bioscience-271	465	33	blood	blood	NOUN
bioscience-271	465	34	-	-	PUNCT
bioscience-271	465	35	brain	brain	NOUN
bioscience-271	465	36	barrier	barrier	NOUN
bioscience-271	465	37	in	in	ADP
bioscience-271	465	38	neonate	neonate	NOUN
bioscience-271	465	39	rats	rat	NOUN
bioscience-271	465	40	after	after	ADP
bioscience-271	465	41	meningitis	meningitis	NOUN
bioscience-271	465	42	by	by	ADP
bioscience-271	465	43	streptococcus	streptococcus	NOUN
bioscience-271	465	44	agalactiae	agalactiae	NOUN
bioscience-271	465	45	.	.	PUNCT
bioscience-271	466	1	neurochemical	neurochemical	ADJ
bioscience-271	466	2	research	research	NOUN
bioscience-271	466	3	.	.	PUNCT
bioscience-271	467	1	2011;36:1922	2011;36:1922	NUM
bioscience-271	467	2	-	-	SYM
bioscience-271	467	3	30	30	NUM
bioscience-271	467	4	.	.	PUNCT
bioscience-271	468	1	48	48	NUM
bioscience-271	468	2	.	.	PUNCT
bioscience-271	469	1	van	van	PROPN
bioscience-271	469	2	doan	doan	PROPN
bioscience-271	469	3	h	h	NOUN
bioscience-271	469	4	,	,	PUNCT
bioscience-271	469	5	soltani	soltani	PROPN
bioscience-271	469	6	m	m	PROPN
bioscience-271	469	7	,	,	PUNCT
bioscience-271	469	8	leitão	leitão	PROPN
bioscience-271	469	9	a	a	PRON
bioscience-271	469	10	,	,	PUNCT
bioscience-271	469	11	shafiei	shafiei	PROPN
bioscience-271	469	12	s	s	PROPN
bioscience-271	469	13	,	,	PUNCT
bioscience-271	469	14	asadi	asadi	PROPN
bioscience-271	469	15	s	s	PROPN
bioscience-271	469	16	,	,	PUNCT
bioscience-271	469	17	lymbery	lymbery	PROPN
bioscience-271	469	18	aj	aj	PROPN
bioscience-271	469	19	,	,	PUNCT
bioscience-271	469	20	et	et	PROPN
bioscience-271	469	21	al	al	PROPN
bioscience-271	469	22	.	.	PUNCT
bioscience-271	470	1	streptococcosis	streptococcosis	PROPN
bioscience-271	470	2	:	:	PUNCT
bioscience-271	470	3	a	a	DET
bioscience-271	470	4	re	re	ADJ
bioscience-271	470	5	-	-	ADJ
bioscience-271	470	6	emerging	emerge	VERB
bioscience-271	470	7	disease	disease	NOUN
bioscience-271	470	8	in	in	ADP
bioscience-271	470	9	aquaculture	aquaculture	NOUN
bioscience-271	470	10	:	:	PUNCT
bioscience-271	470	11	significance	significance	NOUN
bioscience-271	470	12	and	and	CCONJ
bioscience-271	470	13	phytotherapy	phytotherapy	NOUN
bioscience-271	470	14	.	.	PUNCT
bioscience-271	471	1	animals	animal	NOUN
bioscience-271	471	2	.	.	PUNCT
bioscience-271	472	1	2022;12:2443	2022;12:2443	NUM
bioscience-271	472	2	.	.	NOUN
bioscience-271	472	3	49	49	NUM
bioscience-271	472	4	.	.	PUNCT
bioscience-271	473	1	ghetas	gheta	NOUN
bioscience-271	473	2	h	h	PROPN
bioscience-271	473	3	,	,	PUNCT
bioscience-271	473	4	neiana	neiana	PROPN
bioscience-271	473	5	a	a	PRON
bioscience-271	473	6	,	,	PUNCT
bioscience-271	473	7	khalil	khalil	PROPN
bioscience-271	473	8	r	r	PROPN
bioscience-271	473	9	,	,	PUNCT
bioscience-271	473	10	khallaf	khallaf	PROPN
bioscience-271	473	11	m.	m.	NOUN
bioscience-271	473	12	streptococcus	streptococcus	VERB
bioscience-271	473	13	agalactiae	agalactiae	ADJ
bioscience-271	473	14	isolation	isolation	NOUN
bioscience-271	473	15	and	and	CCONJ
bioscience-271	473	16	characterization	characterization	NOUN
bioscience-271	473	17	in	in	ADP
bioscience-271	473	18	nile	nile	PROPN
bioscience-271	473	19	tilapia	tilapia	PROPN
bioscience-271	473	20	(	(	PUNCT
bioscience-271	473	21	oreochromis	oreochromis	NOUN
bioscience-271	473	22	niloticus	niloticus	PROPN
bioscience-271	473	23	)	)	PUNCT
bioscience-271	473	24	with	with	ADP
bioscience-271	473	25	histopathological	histopathological	ADJ
bioscience-271	473	26	studies	study	NOUN
bioscience-271	473	27	.	.	PUNCT
bioscience-271	474	1	journal	journal	PROPN
bioscience-271	474	2	of	of	ADP
bioscience-271	474	3	current	current	ADJ
bioscience-271	474	4	veterinary	veterinary	ADJ
bioscience-271	474	5	research	research	NOUN
bioscience-271	474	6	.	.	PUNCT
bioscience-271	475	1	2021;3(1):70	2021;3(1):70	NUM
bioscience-271	475	2	-	-	SYM
bioscience-271	475	3	9	9	NUM
bioscience-271	475	4	.	.	NOUN
bioscience-271	475	5	50	50	NUM
bioscience-271	475	6	.	.	PUNCT
bioscience-271	476	1	vinarukwong	vinarukwong	PROPN
bioscience-271	476	2	n	n	CCONJ
bioscience-271	476	3	,	,	PUNCT
bioscience-271	476	4	lukkana	lukkana	PROPN
bioscience-271	476	5	m	m	PROPN
bioscience-271	476	6	,	,	PUNCT
bioscience-271	476	7	berntsen	berntsen	PROPN
bioscience-271	476	8	jo	jo	PROPN
bioscience-271	476	9	,	,	PUNCT
bioscience-271	476	10	wongtavatchai	wongtavatchai	PROPN
bioscience-271	476	11	j.	j.	PROPN
bioscience-271	476	12	therapeutic	therapeutic	ADJ
bioscience-271	476	13	use	use	NOUN
bioscience-271	476	14	of	of	ADP
bioscience-271	476	15	sulfadimethoxine	sulfadimethoxine	NOUN
bioscience-271	476	16	-	-	PUNCT
bioscience-271	476	17	ormetoprim	ormetoprim	NOUN
bioscience-271	476	18	for	for	ADP
bioscience-271	476	19	control	control	NOUN
bioscience-271	476	20	of	of	ADP
bioscience-271	476	21	streptococcus	streptococcus	NOUN
bioscience-271	476	22	agalactiae	agalactiae	ADJ
bioscience-271	476	23	infection	infection	NOUN
bioscience-271	476	24	in	in	ADP
bioscience-271	476	25	nile	nile	PROPN
bioscience-271	476	26	tilapia	tilapia	PROPN
bioscience-271	476	27	(	(	PUNCT
bioscience-271	476	28	oreochromis	oreochromis	PROPN
bioscience-271	476	29	niloticus	niloticus	PROPN
bioscience-271	476	30	)	)	PUNCT
bioscience-271	476	31	fry	fry	PROPN
bioscience-271	476	32	.	.	PROPN
bioscience-271	476	33	thai	thai	PROPN
bioscience-271	476	34	journal	journal	PROPN
bioscience-271	476	35	of	of	ADP
bioscience-271	476	36	veterinary	veterinary	ADJ
bioscience-271	476	37	medicine	medicine	NOUN
bioscience-271	476	38	.	.	PUNCT
bioscience-271	477	1	2018;48(3):367	2018;48(3):367	NUM
bioscience-271	477	2	-	-	SYM
bioscience-271	477	3	73	73	NUM
bioscience-271	477	4	.	.	PUNCT
bioscience-271	478	1	51	51	NUM
bioscience-271	478	2	.	.	PUNCT
bioscience-271	478	3	bowker	bowker	PROPN
bioscience-271	478	4	jd	jd	PROPN
bioscience-271	478	5	,	,	PUNCT
bioscience-271	478	6	ostland	ostland	PROPN
bioscience-271	478	7	d	d	PROPN
bioscience-271	478	8	,	,	PUNCT
bioscience-271	478	9	bowman	bowman	PROPN
bioscience-271	478	10	mp	mp	PROPN
bioscience-271	478	11	.	.	PROPN
bioscience-271	478	12	effectiveness	effectiveness	NOUN
bioscience-271	478	13	of	of	ADP
bioscience-271	478	14	aquaflor	aquaflor	NOUN
bioscience-271	478	15	(	(	PUNCT
bioscience-271	478	16	50	50	NUM
bioscience-271	478	17	%	%	NOUN
bioscience-271	478	18	florfenicol	florfenicol	NOUN
bioscience-271	478	19	)	)	PUNCT
bioscience-271	478	20	to	to	PART
bioscience-271	478	21	control	control	VERB
bioscience-271	478	22	mortality	mortality	NOUN
bioscience-271	478	23	associated	associate	VERB
bioscience-271	478	24	with	with	ADP
bioscience-271	478	25	streptococcus	streptococcus	NOUN
bioscience-271	478	26	iniae	iniae	NOUN
bioscience-271	478	27	in	in	ADP
bioscience-271	478	28	freshwater	freshwater	NOUN
bioscience-271	478	29	-	-	PUNCT
bioscience-271	478	30	reared	rear	VERB
bioscience-271	478	31	subadult	subadult	NOUN
bioscience-271	478	32	sunshine	sunshine	NOUN
bioscience-271	478	33	bass	bass	PROPN
bioscience-271	478	34	.	.	PUNCT
bioscience-271	479	1	journal	journal	PROPN
bioscience-271	479	2	of	of	ADP
bioscience-271	479	3	aquatic	aquatic	ADJ
bioscience-271	479	4	animal	animal	NOUN
bioscience-271	479	5	health	health	NOUN
bioscience-271	479	6	.	.	PUNCT
bioscience-271	480	1	2010;22(4):254	2010;22(4):254	NUM
bioscience-271	480	2	-	-	PUNCT
bioscience-271	480	3	65	65	NUM
bioscience-271	480	4	.	.	PUNCT
bioscience-271	480	5	52	52	NUM
bioscience-271	480	6	.	.	PUNCT
bioscience-271	480	7	zahari	zahari	PROPN
bioscience-271	480	8	nin	nin	PROPN
bioscience-271	480	9	,	,	PUNCT
bioscience-271	480	10	rahman	rahman	PROPN
bioscience-271	480	11	ea	ea	PROPN
bioscience-271	480	12	,	,	PUNCT
bioscience-271	480	13	irekeola	irekeola	PROPN
bioscience-271	480	14	aa	aa	PROPN
bioscience-271	480	15	,	,	PUNCT
bioscience-271	480	16	ahmed	ahmed	PROPN
bioscience-271	480	17	n	n	CCONJ
bioscience-271	480	18	,	,	PUNCT
bioscience-271	480	19	rabaan	rabaan	PROPN
bioscience-271	480	20	aa	aa	PROPN
bioscience-271	480	21	,	,	PUNCT
bioscience-271	480	22	alotaibi	alotaibi	PROPN
bioscience-271	480	23	j	j	PROPN
bioscience-271	480	24	,	,	PUNCT
bioscience-271	480	25	et	et	PROPN
bioscience-271	480	26	al	al	PROPN
bioscience-271	480	27	.	.	PUNCT
bioscience-271	481	1	a	a	DET
bioscience-271	481	2	review	review	NOUN
bioscience-271	481	3	of	of	ADP
bioscience-271	481	4	the	the	DET
bioscience-271	481	5	resistance	resistance	NOUN
bioscience-271	481	6	mechanisms	mechanism	NOUN
bioscience-271	481	7	for	for	ADP
bioscience-271	481	8	-lactams	-lactam	NOUN
bioscience-271	481	9	,	,	PUNCT
bioscience-271	481	10	macrolides	macrolide	NOUN
bioscience-271	481	11	and	and	CCONJ
bioscience-271	481	12	fluoroquinolones	fluoroquinolone	NOUN
bioscience-271	481	13	among	among	ADP
bioscience-271	481	14	streptococcus	streptococcus	NOUN
bioscience-271	481	15	pneumoniae	pneumoniae	NOUN
bioscience-271	481	16	.	.	PUNCT
bioscience-271	482	1	medicina	medicina	NOUN
bioscience-271	482	2	.	.	PUNCT
bioscience-271	483	1	2023;59(11):1927	2023;59(11):1927	NUM
bioscience-271	483	2	.	.	NOUN
bioscience-271	483	3	53	53	NUM
bioscience-271	483	4	.	.	PUNCT
bioscience-271	484	1	hensler	hensler	NOUN
bioscience-271	484	2	me	me	PROPN
bioscience-271	484	3	,	,	PUNCT
bioscience-271	484	4	quach	quach	NOUN
bioscience-271	484	5	d	d	PROPN
bioscience-271	484	6	,	,	PUNCT
bioscience-271	484	7	hsieh	hsieh	PROPN
bioscience-271	484	8	cj	cj	PROPN
bioscience-271	484	9	,	,	PUNCT
bioscience-271	484	10	doran	doran	PROPN
bioscience-271	484	11	ks	ks	PROPN
bioscience-271	484	12	,	,	PUNCT
bioscience-271	484	13	nizet	nizet	PROPN
bioscience-271	484	14	v.	v.	CCONJ
bioscience-271	484	15	camp	camp	NOUN
bioscience-271	484	16	factor	factor	NOUN
bioscience-271	484	17	is	be	AUX
bioscience-271	484	18	not	not	PART
bioscience-271	484	19	essential	essential	ADJ
bioscience-271	484	20	for	for	ADP
bioscience-271	484	21	systemic	systemic	ADJ
bioscience-271	484	22	virulence	virulence	NOUN
bioscience-271	484	23	of	of	ADP
bioscience-271	484	24	group	group	NOUN
bioscience-271	484	25	b	b	PROPN
bioscience-271	484	26	streptococcus	streptococcus	NOUN
bioscience-271	484	27	.	.	PUNCT
bioscience-271	485	1	microbial	microbial	ADJ
bioscience-271	485	2	pathogenesis	pathogenesis	NOUN
bioscience-271	485	3	.	.	PUNCT
bioscience-271	486	1	2008;44(1):84	2008;44(1):84	NOUN
bioscience-271	486	2	-	-	SYM
bioscience-271	486	3	8	8	NUM
bioscience-271	486	4	.	.	PUNCT
bioscience-271	487	1	highlights	highlight	NOUN
bioscience-271	487	2	in	in	ADP
bioscience-271	487	3	bioscience	bioscience	NOUN
bioscience-271	487	4	page	page	NOUN
bioscience-271	487	5	10	10	NUM
bioscience-271	487	6	of	of	ADP
bioscience-271	487	7	10	10	NUM
bioscience-271	487	8	october	october	PROPN
bioscience-271	487	9	2025|volume	2025|volume	NUM
bioscience-271	487	10	8	8	NUM
bioscience-271	487	11	http://bioscience.highlightsin.org/	http://bioscience.highlightsin.org/	PRON
bioscience-271	487	12	abstract	abstract	ADJ
bioscience-271	487	13	introduction	introduction	NOUN
bioscience-271	487	14	materials	material	NOUN
bioscience-271	487	15	and	and	CCONJ
bioscience-271	487	16	methods	method	NOUN
bioscience-271	487	17	experimental	experimental	ADJ
bioscience-271	487	18	fish	fish	NOUN
bioscience-271	487	19	and	and	CCONJ
bioscience-271	487	20	bacterial	bacterial	ADJ
bioscience-271	487	21	strain	strain	NOUN
bioscience-271	487	22	and	and	CCONJ
bioscience-271	487	23	its	its	PRON
bioscience-271	487	24	pathogenicity	pathogenicity	NOUN
bioscience-271	487	25	efficacy	efficacy	NOUN
bioscience-271	487	26	of	of	ADP
bioscience-271	487	27	oxolinic	oxolinic	ADJ
bioscience-271	487	28	acid	acid	NOUN
bioscience-271	487	29	against	against	ADP
bioscience-271	487	30	streptococcus	streptococcus	NOUN
bioscience-271	487	31	agalactiae	agalactiae	ADJ
bioscience-271	487	32	infection	infection	NOUN
bioscience-271	487	33	histopathology	histopathology	NOUN
bioscience-271	487	34	and	and	CCONJ
bioscience-271	487	35	evaluation	evaluation	NOUN
bioscience-271	487	36	of	of	ADP
bioscience-271	487	37	pathological	pathological	ADJ
bioscience-271	487	38	anomalies	anomaly	NOUN
bioscience-271	487	39	in	in	ADP
bioscience-271	487	40	silico	silico	NOUN
bioscience-271	487	41	and	and	CCONJ
bioscience-271	487	42	molecular	molecular	ADJ
bioscience-271	487	43	docking	docking	NOUN
bioscience-271	487	44	of	of	ADP
bioscience-271	487	45	streptococcus	streptococcus	NOUN
bioscience-271	487	46	agalactiae	agalactiae	ADJ
bioscience-271	487	47	virulence	virulence	NOUN
bioscience-271	487	48	factors	factor	NOUN
bioscience-271	487	49	results	result	VERB
bioscience-271	487	50	brain	brain	NOUN
bioscience-271	487	51	histopathology	histopathology	NOUN
bioscience-271	487	52	and	and	CCONJ
bioscience-271	487	53	evaluation	evaluation	NOUN
bioscience-271	487	54	of	of	ADP
bioscience-271	487	55	pathological	pathological	ADJ
bioscience-271	487	56	anomalies	anomaly	NOUN
bioscience-271	487	57	homology	homology	VERB
bioscience-271	487	58	modelling	modelling	NOUN
bioscience-271	487	59	and	and	CCONJ
bioscience-271	487	60	molecular	molecular	ADJ
bioscience-271	487	61	docking	docking	NOUN
bioscience-271	487	62	discussions	discussion	NOUN
bioscience-271	487	63	conclusions	conclusion	NOUN
bioscience-271	487	64	data	datum	NOUN
bioscience-271	487	65	availability	availability	NOUN
bioscience-271	487	66	statement	statement	NOUN
bioscience-271	487	67	funding	fund	VERB
bioscience-271	487	68	competing	compete	VERB
bioscience-271	487	69	interests	interest	NOUN