id	sid	tid	token	lemma	pos
hjic-106	1	1	microsoft	microsoft	PROPN
hjic-106	1	2	word	word	NOUN
hjic-106	1	3	contents.doc	contents.doc	X
hjic-106	1	4	hungarian	hungarian	ADJ
hjic-106	1	5	journal	journal	NOUN
hjic-106	1	6	of	of	ADP
hjic-106	1	7	industrial	industrial	ADJ
hjic-106	1	8	chemistry	chemistry	NOUN
hjic-106	1	9	veszprém	veszprém	NOUN
hjic-106	1	10	vol	vol	NOUN
hjic-106	1	11	.	.	PUNCT
hjic-106	2	1	34	34	NUM
hjic-106	2	2	.	.	PUNCT
hjic-106	3	1	pp	pp	ADJ
hjic-106	3	2	.	.	PUNCT
hjic-106	4	1	15	15	NUM
hjic-106	4	2	-	-	SYM
hjic-106	4	3	20	20	NUM
hjic-106	4	4	(	(	PUNCT
hjic-106	4	5	2006	2006	NUM
hjic-106	4	6	)	)	PUNCT
hjic-106	4	7	quasi	quasi	ADJ
hjic-106	4	8	-	-	ADJ
hjic-106	4	9	continuous	continuous	ADJ
hjic-106	4	10	elution	elution	NOUN
hjic-106	4	11	chromatographic	chromatographic	ADJ
hjic-106	4	12	purification	purification	NOUN
hjic-106	4	13	of	of	ADP
hjic-106	4	14	a	a	DET
hjic-106	4	15	steroid	steroid	NOUN
hjic-106	4	16	active	active	ADJ
hjic-106	4	17	compound	compound	NOUN
hjic-106	4	18	k.	k.	PROPN
hjic-106	4	19	temesvári1	temesvári1	PROPN
hjic-106	4	20	,	,	PUNCT
hjic-106	4	21	,	,	PUNCT
hjic-106	4	22	a.	a.	PROPN
hjic-106	4	23	aranyi1	aranyi1	PROPN
hjic-106	4	24	,	,	PUNCT
hjic-106	4	25	z.	z.	PROPN
hjic-106	4	26	horváth1	horváth1	PROPN
hjic-106	4	27	,	,	PUNCT
hjic-106	4	28	m.	m.	NOUN
hjic-106	4	29	nagy2	nagy2	PROPN
hjic-106	4	30	,	,	PUNCT
hjic-106	4	31	t.	t.	NOUN
hjic-106	4	32	szánya2	szánya2	PROPN
hjic-106	4	33	and	and	CCONJ
hjic-106	4	34	l.	l.	PROPN
hjic-106	4	35	hanák2	hanák2	PROPN
hjic-106	5	1	1gedeon	1gedeon	NUM
hjic-106	5	2	richter	richter	PROPN
hjic-106	5	3	ltd	ltd	PROPN
hjic-106	5	4	.	.	PROPN
hjic-106	5	5	,	,	PUNCT
hjic-106	6	1	h-1475	h-1475	PROPN
hjic-106	6	2	budapest	budapest	PROPN
hjic-106	6	3	10	10	NUM
hjic-106	6	4	.	.	PUNCT
hjic-106	6	5	po	po	PROPN
hjic-106	6	6	box	box	PROPN
hjic-106	6	7	27	27	NUM
hjic-106	6	8	.	.	PUNCT
hjic-106	7	1	hungary	hungary	PROPN
hjic-106	7	2	;	;	PUNCT
hjic-106	7	3	e	e	X
hjic-106	7	4	-	-	NOUN
hjic-106	7	5	mail	mail	NOUN
hjic-106	7	6	:	:	PUNCT
hjic-106	7	7	k.temesvari@richter.hu	k.temesvari@richter.hu	X
hjic-106	8	1	2university	2university	NUM
hjic-106	8	2	of	of	ADP
hjic-106	8	3	pannon	pannon	NOUN
hjic-106	8	4	,	,	PUNCT
hjic-106	8	5	department	department	NOUN
hjic-106	8	6	of	of	ADP
hjic-106	8	7	chemical	chemical	PROPN
hjic-106	8	8	engineering	engineering	PROPN
hjic-106	8	9	pob	pob	PROPN
hjic-106	8	10	158	158	NUM
hjic-106	8	11	,	,	PUNCT
hjic-106	8	12	veszprém	veszprém	NOUN
hjic-106	8	13	,	,	PUNCT
hjic-106	8	14	h-8201	h-8201	PROPN
hjic-106	8	15	,	,	PUNCT
hjic-106	8	16	hungary	hungary	NOUN
hjic-106	8	17	a	a	DET
hjic-106	8	18	pilot	pilot	NOUN
hjic-106	8	19	-	-	PUNCT
hjic-106	8	20	scale	scale	NOUN
hjic-106	8	21	preparative	preparative	ADJ
hjic-106	8	22	batch	batch	NOUN
hjic-106	8	23	elution	elution	NOUN
hjic-106	8	24	chromatographic	chromatographic	ADJ
hjic-106	8	25	separation	separation	NOUN
hjic-106	8	26	of	of	ADP
hjic-106	8	27	a	a	DET
hjic-106	8	28	steroid	steroid	NOUN
hjic-106	8	29	active	active	ADJ
hjic-106	8	30	compound	compound	NOUN
hjic-106	8	31	from	from	ADP
hjic-106	8	32	its	its	PRON
hjic-106	8	33	impurities	impurity	NOUN
hjic-106	8	34	was	be	AUX
hjic-106	8	35	developed	develop	VERB
hjic-106	8	36	and	and	CCONJ
hjic-106	8	37	is	be	AUX
hjic-106	8	38	applied	apply	VERB
hjic-106	8	39	at	at	ADP
hjic-106	8	40	our	our	PRON
hjic-106	8	41	company	company	NOUN
hjic-106	8	42	.	.	PUNCT
hjic-106	9	1	the	the	DET
hjic-106	9	2	process	process	NOUN
hjic-106	9	3	consists	consist	VERB
hjic-106	9	4	of	of	ADP
hjic-106	9	5	the	the	DET
hjic-106	9	6	following	follow	VERB
hjic-106	9	7	steps	step	NOUN
hjic-106	9	8	:	:	PUNCT
hjic-106	9	9	(	(	PUNCT
hjic-106	9	10	1	1	NUM
hjic-106	9	11	.	.	PUNCT
hjic-106	9	12	)	)	PUNCT
hjic-106	10	1	injection	injection	NOUN
hjic-106	10	2	of	of	ADP
hjic-106	10	3	the	the	DET
hjic-106	10	4	crude	crude	ADJ
hjic-106	10	5	sample	sample	NOUN
hjic-106	10	6	solved	solve	VERB
hjic-106	10	7	in	in	ADP
hjic-106	10	8	the	the	DET
hjic-106	10	9	eluent	eluent	NOUN
hjic-106	10	10	onto	onto	ADP
hjic-106	10	11	the	the	DET
hjic-106	10	12	chromatographic	chromatographic	ADJ
hjic-106	10	13	column	column	NOUN
hjic-106	10	14	,	,	PUNCT
hjic-106	10	15	(	(	PUNCT
hjic-106	10	16	2	2	NUM
hjic-106	10	17	.	.	PUNCT
hjic-106	10	18	)	)	PUNCT
hjic-106	11	1	elution	elution	NOUN
hjic-106	11	2	of	of	ADP
hjic-106	11	3	the	the	DET
hjic-106	11	4	less	less	ADV
hjic-106	11	5	retained	retain	VERB
hjic-106	11	6	impurities	impurity	NOUN
hjic-106	11	7	with	with	ADP
hjic-106	11	8	the	the	DET
hjic-106	11	9	eluent	eluent	NOUN
hjic-106	11	10	,	,	PUNCT
hjic-106	11	11	(	(	PUNCT
hjic-106	11	12	3	3	NUM
hjic-106	11	13	.	.	PUNCT
hjic-106	11	14	)	)	PUNCT
hjic-106	12	1	elution	elution	NOUN
hjic-106	12	2	of	of	ADP
hjic-106	12	3	the	the	DET
hjic-106	12	4	pure	pure	ADJ
hjic-106	12	5	fraction	fraction	NOUN
hjic-106	12	6	of	of	ADP
hjic-106	12	7	the	the	DET
hjic-106	12	8	active	active	ADJ
hjic-106	12	9	compound	compound	NOUN
hjic-106	12	10	(	(	PUNCT
hjic-106	12	11	main	main	ADJ
hjic-106	12	12	fraction	fraction	NOUN
hjic-106	12	13	)	)	PUNCT
hjic-106	12	14	with	with	ADP
hjic-106	12	15	the	the	DET
hjic-106	12	16	eluent	eluent	NOUN
hjic-106	12	17	,	,	PUNCT
hjic-106	12	18	(	(	PUNCT
hjic-106	12	19	4	4	NUM
hjic-106	12	20	.	.	PUNCT
hjic-106	12	21	)	)	PUNCT
hjic-106	12	22	back	back	ADV
hjic-106	12	23	-	-	PUNCT
hjic-106	12	24	flushing	flush	VERB
hjic-106	12	25	the	the	DET
hjic-106	12	26	column	column	NOUN
hjic-106	12	27	with	with	ADP
hjic-106	12	28	the	the	DET
hjic-106	12	29	more	more	ADV
hjic-106	12	30	polar	polar	ADJ
hjic-106	12	31	solvent	solvent	ADJ
hjic-106	12	32	component	component	NOUN
hjic-106	12	33	of	of	ADP
hjic-106	12	34	the	the	DET
hjic-106	12	35	eluent	eluent	NOUN
hjic-106	12	36	to	to	PART
hjic-106	12	37	remove	remove	VERB
hjic-106	12	38	the	the	DET
hjic-106	12	39	strongly	strongly	ADV
hjic-106	12	40	retained	retain	VERB
hjic-106	12	41	compounds	compound	NOUN
hjic-106	12	42	,	,	PUNCT
hjic-106	12	43	(	(	PUNCT
hjic-106	12	44	5	5	NUM
hjic-106	12	45	.	.	PUNCT
hjic-106	12	46	)	)	PUNCT
hjic-106	13	1	conditioning	condition	VERB
hjic-106	13	2	the	the	DET
hjic-106	13	3	column	column	NOUN
hjic-106	13	4	with	with	ADP
hjic-106	13	5	the	the	DET
hjic-106	13	6	eluent	eluent	NOUN
hjic-106	13	7	to	to	PART
hjic-106	13	8	prepare	prepare	VERB
hjic-106	13	9	for	for	ADP
hjic-106	13	10	the	the	DET
hjic-106	13	11	next	next	ADJ
hjic-106	13	12	injection	injection	NOUN
hjic-106	13	13	.	.	PUNCT
hjic-106	14	1	the	the	DET
hjic-106	14	2	above	above	ADV
hjic-106	14	3	mentioned	mention	VERB
hjic-106	14	4	five	five	NUM
hjic-106	14	5	-	-	PUNCT
hjic-106	14	6	step	step	NOUN
hjic-106	14	7	chromatographic	chromatographic	ADJ
hjic-106	14	8	process	process	NOUN
hjic-106	14	9	can	can	AUX
hjic-106	14	10	be	be	AUX
hjic-106	14	11	realized	realize	VERB
hjic-106	14	12	quasi	quasi	ADJ
hjic-106	14	13	-	-	ADJ
hjic-106	14	14	continuously	continuously	ADV
hjic-106	14	15	by	by	ADP
hjic-106	14	16	applying	apply	VERB
hjic-106	14	17	the	the	DET
hjic-106	14	18	simulated	simulated	ADJ
hjic-106	14	19	moving	move	VERB
hjic-106	14	20	bed	bed	NOUN
hjic-106	14	21	(	(	PUNCT
hjic-106	14	22	smb	smb	NOUN
hjic-106	14	23	)	)	PUNCT
hjic-106	14	24	instrument	instrument	NOUN
hjic-106	14	25	.	.	PUNCT
hjic-106	15	1	the	the	DET
hjic-106	15	2	subsequent	subsequent	ADJ
hjic-106	15	3	steps	step	NOUN
hjic-106	15	4	can	can	AUX
hjic-106	15	5	be	be	AUX
hjic-106	15	6	carried	carry	VERB
hjic-106	15	7	out	out	ADP
hjic-106	15	8	in	in	ADP
hjic-106	15	9	parallel	parallel	NOUN
hjic-106	15	10	in	in	ADP
hjic-106	15	11	the	the	DET
hjic-106	15	12	zones	zone	NOUN
hjic-106	15	13	of	of	ADP
hjic-106	15	14	the	the	DET
hjic-106	15	15	smb	smb	PROPN
hjic-106	15	16	unit	unit	NOUN
hjic-106	15	17	,	,	PUNCT
hjic-106	15	18	which	which	PRON
hjic-106	15	19	are	be	AUX
hjic-106	15	20	independent	independent	ADJ
hjic-106	15	21	from	from	ADP
hjic-106	15	22	each	each	DET
hjic-106	15	23	other	other	ADJ
hjic-106	15	24	in	in	ADP
hjic-106	15	25	this	this	DET
hjic-106	15	26	special	special	ADJ
hjic-106	15	27	case	case	NOUN
hjic-106	15	28	.	.	PUNCT
hjic-106	16	1	in	in	ADP
hjic-106	16	2	our	our	PRON
hjic-106	16	3	present	present	ADJ
hjic-106	16	4	paper	paper	NOUN
hjic-106	16	5	the	the	DET
hjic-106	16	6	elaborated	elaborate	VERB
hjic-106	16	7	quasi	quasi	ADJ
hjic-106	16	8	-	-	ADJ
hjic-106	16	9	continuous	continuous	ADJ
hjic-106	16	10	elution	elution	NOUN
hjic-106	16	11	chromatographic	chromatographic	ADJ
hjic-106	16	12	separation	separation	NOUN
hjic-106	16	13	is	be	AUX
hjic-106	16	14	shown	show	VERB
hjic-106	16	15	using	use	VERB
hjic-106	16	16	the	the	DET
hjic-106	16	17	following	follow	VERB
hjic-106	16	18	instrument	instrument	NOUN
hjic-106	16	19	set	set	VERB
hjic-106	16	20	up	up	ADP
hjic-106	16	21	and	and	CCONJ
hjic-106	16	22	experimental	experimental	ADJ
hjic-106	16	23	conditions	condition	NOUN
hjic-106	16	24	:	:	PUNCT
hjic-106	16	25	a	a	DET
hjic-106	16	26	knauer	knauer	NOUN
hjic-106	16	27	csep	csep	NOUN
hjic-106	16	28	9116	9116	NUM
hjic-106	16	29	laboratory	laboratory	NOUN
hjic-106	16	30	-	-	PUNCT
hjic-106	16	31	scale	scale	NOUN
hjic-106	16	32	smb	smb	NOUN
hjic-106	16	33	unit	unit	NOUN
hjic-106	16	34	with	with	ADP
hjic-106	16	35	five	five	NUM
hjic-106	16	36	knauer	knauer	NOUN
hjic-106	16	37	k-501	k-501	NOUN
hjic-106	16	38	hplc	hplc	PROPN
hjic-106	16	39	pumps	pump	NOUN
hjic-106	16	40	and	and	CCONJ
hjic-106	16	41	eight	eight	NUM
hjic-106	16	42	columns	column	NOUN
hjic-106	16	43	(	(	PUNCT
hjic-106	16	44	column	column	NOUN
hjic-106	16	45	dimension	dimension	NOUN
hjic-106	16	46	:	:	PUNCT
hjic-106	16	47	250x16	250x16	NUM
hjic-106	16	48	mm	mm	INTJ
hjic-106	16	49	i.d	i.d	PROPN
hjic-106	16	50	.	.	PROPN
hjic-106	16	51	)	)	PUNCT
hjic-106	16	52	.	.	PUNCT
hjic-106	17	1	the	the	DET
hjic-106	17	2	columns	column	NOUN
hjic-106	17	3	were	be	AUX
hjic-106	17	4	packed	pack	VERB
hjic-106	17	5	in	in	ADP
hjic-106	17	6	our	our	PRON
hjic-106	17	7	laboratory	laboratory	NOUN
hjic-106	17	8	by	by	ADP
hjic-106	17	9	dry	dry	ADJ
hjic-106	17	10	-	-	PUNCT
hjic-106	17	11	packing	pack	VERB
hjic-106	17	12	method	method	NOUN
hjic-106	17	13	using	use	VERB
hjic-106	17	14	vibration	vibration	NOUN
hjic-106	17	15	,	,	PUNCT
hjic-106	17	16	the	the	DET
hjic-106	17	17	applied	apply	VERB
hjic-106	17	18	packing	packing	NOUN
hjic-106	17	19	material	material	NOUN
hjic-106	17	20	was	be	AUX
hjic-106	17	21	uetikon	uetikon	PROPN
hjic-106	17	22	c-490	c-490	VERB
hjic-106	17	23	15	15	NUM
hjic-106	17	24	-	-	SYM
hjic-106	17	25	35	35	NUM
hjic-106	17	26	μm	μm	NUM
hjic-106	17	27	si	si	NOUN
hjic-106	17	28	gel	gel	NOUN
hjic-106	17	29	.	.	PUNCT
hjic-106	18	1	the	the	DET
hjic-106	18	2	appropriate	appropriate	ADJ
hjic-106	18	3	eluent	eluent	NOUN
hjic-106	18	4	was	be	AUX
hjic-106	18	5	methylene	methylene	ADJ
hjic-106	18	6	chloride	chloride	NOUN
hjic-106	18	7	/	/	SYM
hjic-106	18	8	ethyl	ethyl	PROPN
hjic-106	18	9	acetate	acetate	NOUN
hjic-106	18	10	mixture	mixture	NOUN
hjic-106	18	11	and	and	CCONJ
hjic-106	18	12	as	as	ADP
hjic-106	18	13	back	back	ADV
hjic-106	18	14	-	-	PUNCT
hjic-106	18	15	flushing	flush	VERB
hjic-106	18	16	solvent	solvent	NOUN
hjic-106	18	17	,	,	PUNCT
hjic-106	18	18	pure	pure	ADJ
hjic-106	18	19	ethyl	ethyl	PROPN
hjic-106	18	20	acetate	acetate	PROPN
hjic-106	18	21	was	be	AUX
hjic-106	18	22	used	use	VERB
hjic-106	18	23	.	.	PUNCT
hjic-106	19	1	after	after	ADP
hjic-106	19	2	the	the	DET
hjic-106	19	3	elaboration	elaboration	NOUN
hjic-106	19	4	of	of	ADP
hjic-106	19	5	quasi	quasi	ADJ
hjic-106	19	6	-	-	ADJ
hjic-106	19	7	continuous	continuous	ADJ
hjic-106	19	8	elution	elution	NOUN
hjic-106	19	9	chromatographic	chromatographic	ADJ
hjic-106	19	10	purification	purification	NOUN
hjic-106	19	11	,	,	PUNCT
hjic-106	19	12	the	the	DET
hjic-106	19	13	intensification	intensification	NOUN
hjic-106	19	14	of	of	ADP
hjic-106	19	15	the	the	DET
hjic-106	19	16	process	process	NOUN
hjic-106	19	17	was	be	AUX
hjic-106	19	18	carried	carry	VERB
hjic-106	19	19	out	out	ADP
hjic-106	19	20	.	.	PUNCT
hjic-106	20	1	the	the	DET
hjic-106	20	2	specific	specific	ADJ
hjic-106	20	3	capacity	capacity	NOUN
hjic-106	20	4	parameters	parameter	NOUN
hjic-106	20	5	of	of	ADP
hjic-106	20	6	the	the	DET
hjic-106	20	7	best	good	ADJ
hjic-106	20	8	quasi	quasi	ADJ
hjic-106	20	9	-	-	ADJ
hjic-106	20	10	continuous	continuous	ADJ
hjic-106	20	11	experiments	experiment	NOUN
hjic-106	20	12	were	be	AUX
hjic-106	20	13	compared	compare	VERB
hjic-106	20	14	with	with	ADP
hjic-106	20	15	the	the	DET
hjic-106	20	16	performance	performance	NOUN
hjic-106	20	17	parameters	parameter	NOUN
hjic-106	20	18	of	of	ADP
hjic-106	20	19	the	the	DET
hjic-106	20	20	current	current	ADJ
hjic-106	20	21	batch	batch	NOUN
hjic-106	20	22	pilot	pilot	NOUN
hjic-106	20	23	-	-	PUNCT
hjic-106	20	24	scale	scale	NOUN
hjic-106	20	25	separation	separation	NOUN
hjic-106	20	26	of	of	ADP
hjic-106	20	27	the	the	DET
hjic-106	20	28	compound	compound	NOUN
hjic-106	20	29	.	.	PUNCT
hjic-106	21	1	keywords	keyword	NOUN
hjic-106	21	2	:	:	PUNCT
hjic-106	21	3	quasi	quasi	ADJ
hjic-106	21	4	-	-	ADJ
hjic-106	21	5	continuous	continuous	ADJ
hjic-106	21	6	,	,	PUNCT
hjic-106	21	7	pilot	pilot	NOUN
hjic-106	21	8	-	-	PUNCT
hjic-106	21	9	scale	scale	NOUN
hjic-106	21	10	,	,	PUNCT
hjic-106	21	11	preparative	preparative	ADJ
hjic-106	21	12	chromatographic	chromatographic	ADJ
hjic-106	21	13	separation	separation	NOUN
hjic-106	21	14	,	,	PUNCT
hjic-106	21	15	steroid	steroid	NOUN
hjic-106	21	16	,	,	PUNCT
hjic-106	21	17	simulated	simulate	VERB
hjic-106	21	18	moving	move	VERB
hjic-106	21	19	bed	bed	NOUN
hjic-106	21	20	(	(	PUNCT
hjic-106	21	21	smb	smb	NOUN
hjic-106	21	22	)	)	PUNCT
hjic-106	21	23	introduction	introduction	NOUN
hjic-106	21	24	in	in	ADP
hjic-106	21	25	pharmaceutical	pharmaceutical	ADJ
hjic-106	21	26	industry	industry	NOUN
hjic-106	21	27	there	there	PRON
hjic-106	21	28	is	be	VERB
hjic-106	21	29	a	a	DET
hjic-106	21	30	strict	strict	ADJ
hjic-106	21	31	demand	demand	NOUN
hjic-106	21	32	on	on	ADP
hjic-106	21	33	the	the	DET
hjic-106	21	34	quality	quality	NOUN
hjic-106	21	35	of	of	ADP
hjic-106	21	36	active	active	ADJ
hjic-106	21	37	compounds	compound	NOUN
hjic-106	21	38	.	.	PUNCT
hjic-106	22	1	in	in	ADP
hjic-106	22	2	most	most	ADJ
hjic-106	22	3	cases	case	NOUN
hjic-106	22	4	the	the	DET
hjic-106	22	5	amount	amount	NOUN
hjic-106	22	6	of	of	ADP
hjic-106	22	7	all	all	DET
hjic-106	22	8	impurities	impurity	NOUN
hjic-106	22	9	must	must	AUX
hjic-106	22	10	be	be	AUX
hjic-106	22	11	under	under	ADP
hjic-106	22	12	0.5	0.5	NUM
hjic-106	22	13	-	-	SYM
hjic-106	22	14	1	1	NUM
hjic-106	22	15	%	%	NOUN
hjic-106	22	16	,	,	PUNCT
hjic-106	22	17	the	the	DET
hjic-106	22	18	maximum	maximum	ADJ
hjic-106	22	19	level	level	NOUN
hjic-106	22	20	of	of	ADP
hjic-106	22	21	individual	individual	ADJ
hjic-106	22	22	impurities	impurity	NOUN
hjic-106	22	23	had	have	VERB
hjic-106	22	24	to	to	PART
hjic-106	22	25	be	be	AUX
hjic-106	22	26	under	under	ADP
hjic-106	22	27	0.1	0.1	NUM
hjic-106	22	28	%	%	NOUN
hjic-106	22	29	.	.	PUNCT
hjic-106	23	1	in	in	ADP
hjic-106	23	2	many	many	ADJ
hjic-106	23	3	cases	case	NOUN
hjic-106	23	4	these	these	DET
hjic-106	23	5	demands	demand	NOUN
hjic-106	23	6	can	can	AUX
hjic-106	23	7	not	not	PART
hjic-106	23	8	be	be	AUX
hjic-106	23	9	fulfil	fulfil	NOUN
hjic-106	23	10	with	with	ADP
hjic-106	23	11	traditional	traditional	ADJ
hjic-106	23	12	techniques	technique	NOUN
hjic-106	23	13	,	,	PUNCT
hjic-106	23	14	such	such	ADJ
hjic-106	23	15	as	as	ADP
hjic-106	23	16	distillation	distillation	NOUN
hjic-106	23	17	or	or	CCONJ
hjic-106	23	18	crystallization	crystallization	NOUN
hjic-106	23	19	.	.	PUNCT
hjic-106	24	1	pilotand	pilotand	NOUN
hjic-106	24	2	process	process	NOUN
hjic-106	24	3	-	-	PUNCT
hjic-106	24	4	scale	scale	NOUN
hjic-106	24	5	preparative	preparative	ADJ
hjic-106	24	6	chromatographic	chromatographic	ADJ
hjic-106	24	7	processes	process	NOUN
hjic-106	24	8	can	can	AUX
hjic-106	24	9	solve	solve	VERB
hjic-106	24	10	these	these	DET
hjic-106	24	11	difficult	difficult	ADJ
hjic-106	24	12	separation	separation	NOUN
hjic-106	24	13	problems	problem	NOUN
hjic-106	24	14	.	.	PUNCT
hjic-106	25	1	[	[	X
hjic-106	25	2	1	1	X
hjic-106	25	3	]	]	PUNCT
hjic-106	25	4	the	the	DET
hjic-106	25	5	preparative	preparative	ADJ
hjic-106	25	6	chromatographic	chromatographic	ADJ
hjic-106	25	7	processes	process	NOUN
hjic-106	25	8	can	can	AUX
hjic-106	25	9	be	be	AUX
hjic-106	25	10	divided	divide	VERB
hjic-106	25	11	into	into	ADP
hjic-106	25	12	batch	batch	NOUN
hjic-106	25	13	and	and	CCONJ
hjic-106	25	14	continuous	continuous	ADJ
hjic-106	25	15	methods	method	NOUN
hjic-106	25	16	,	,	PUNCT
hjic-106	25	17	depending	depend	VERB
hjic-106	25	18	on	on	ADP
hjic-106	25	19	the	the	DET
hjic-106	25	20	actual	actual	ADJ
hjic-106	25	21	separation	separation	NOUN
hjic-106	25	22	task	task	NOUN
hjic-106	25	23	.	.	PUNCT
hjic-106	26	1	in	in	ADP
hjic-106	26	2	some	some	DET
hjic-106	26	3	cases	case	NOUN
hjic-106	26	4	these	these	DET
hjic-106	26	5	techniques	technique	NOUN
hjic-106	26	6	can	can	AUX
hjic-106	26	7	compete	compete	VERB
hjic-106	26	8	with	with	ADP
hjic-106	26	9	each	each	DET
hjic-106	26	10	other	other	ADJ
hjic-106	26	11	.	.	PUNCT
hjic-106	27	1	[	[	X
hjic-106	27	2	2	2	NUM
hjic-106	27	3	-	-	SYM
hjic-106	27	4	5	5	NUM
hjic-106	27	5	]	]	PUNCT
hjic-106	27	6	the	the	DET
hjic-106	27	7	application	application	NOUN
hjic-106	27	8	areas	area	NOUN
hjic-106	27	9	of	of	ADP
hjic-106	27	10	continuous	continuous	ADJ
hjic-106	27	11	counter	counter	ADJ
hjic-106	27	12	-	-	ADJ
hjic-106	27	13	current	current	ADJ
hjic-106	27	14	separation	separation	NOUN
hjic-106	27	15	methods	method	NOUN
hjic-106	27	16	are	be	AUX
hjic-106	27	17	chiral	chiral	ADJ
hjic-106	27	18	,	,	PUNCT
hjic-106	27	19	isomer	isomer	ADJ
hjic-106	27	20	,	,	PUNCT
hjic-106	27	21	or	or	CCONJ
hjic-106	27	22	other	other	ADJ
hjic-106	27	23	twocomponent	twocomponent	NOUN
hjic-106	27	24	(	(	PUNCT
hjic-106	27	25	or	or	CCONJ
hjic-106	27	26	pseudo	pseudo	NOUN
hjic-106	27	27	two	two	NUM
hjic-106	27	28	-	-	PUNCT
hjic-106	27	29	component	component	NOUN
hjic-106	27	30	)	)	PUNCT
hjic-106	27	31	separation	separation	NOUN
hjic-106	27	32	problems	problem	NOUN
hjic-106	27	33	.	.	PUNCT
hjic-106	28	1	[	[	X
hjic-106	28	2	6	6	NUM
hjic-106	28	3	-	-	SYM
hjic-106	28	4	11	11	NUM
hjic-106	28	5	]	]	PUNCT
hjic-106	28	6	the	the	DET
hjic-106	28	7	simulated	simulate	VERB
hjic-106	28	8	moving	move	VERB
hjic-106	28	9	bed	bed	NOUN
hjic-106	28	10	(	(	PUNCT
hjic-106	28	11	smb	smb	NOUN
hjic-106	28	12	)	)	PUNCT
hjic-106	28	13	technology	technology	NOUN
hjic-106	28	14	is	be	AUX
hjic-106	28	15	the	the	DET
hjic-106	28	16	up	up	ADJ
hjic-106	28	17	-	-	PUNCT
hjic-106	28	18	to	to	ADP
hjic-106	28	19	-	-	PUNCT
hjic-106	28	20	date	date	NOUN
hjic-106	28	21	solution	solution	NOUN
hjic-106	28	22	for	for	ADP
hjic-106	28	23	the	the	DET
hjic-106	28	24	practical	practical	ADJ
hjic-106	28	25	realization	realization	NOUN
hjic-106	28	26	of	of	ADP
hjic-106	28	27	continuous	continuous	ADJ
hjic-106	28	28	,	,	PUNCT
hjic-106	28	29	counter	counter	ADJ
hjic-106	28	30	-	-	ADJ
hjic-106	28	31	current	current	ADJ
hjic-106	28	32	preparative	preparative	ADJ
hjic-106	28	33	chromatographic	chromatographic	ADJ
hjic-106	28	34	processes	process	NOUN
hjic-106	28	35	.	.	PUNCT
hjic-106	29	1	it	it	PRON
hjic-106	29	2	was	be	AUX
hjic-106	29	3	invented	invent	VERB
hjic-106	29	4	and	and	CCONJ
hjic-106	29	5	patented	patent	VERB
hjic-106	29	6	in	in	ADP
hjic-106	29	7	the	the	DET
hjic-106	29	8	late	late	ADJ
hjic-106	29	9	1950	1950	NUM
hjic-106	29	10	’s	’s	NOUN
hjic-106	29	11	and	and	CCONJ
hjic-106	29	12	was	be	AUX
hjic-106	29	13	mainly	mainly	ADV
hjic-106	29	14	applied	apply	VERB
hjic-106	29	15	in	in	ADP
hjic-106	29	16	the	the	DET
hjic-106	29	17	petrochemical	petrochemical	NOUN
hjic-106	29	18	and	and	CCONJ
hjic-106	29	19	sugar	sugar	NOUN
hjic-106	29	20	industries	industry	NOUN
hjic-106	29	21	for	for	ADP
hjic-106	29	22	large	large	ADJ
hjic-106	29	23	-	-	PUNCT
hjic-106	29	24	scale	scale	NOUN
hjic-106	29	25	separations	separation	NOUN
hjic-106	29	26	.	.	PUNCT
hjic-106	30	1	smb	smb	PROPN
hjic-106	30	2	has	have	AUX
hjic-106	30	3	been	be	AUX
hjic-106	30	4	introduced	introduce	VERB
hjic-106	30	5	in	in	ADP
hjic-106	30	6	the	the	DET
hjic-106	30	7	pharmaceutical	pharmaceutical	NOUN
hjic-106	30	8	industry	industry	NOUN
hjic-106	30	9	since	since	SCONJ
hjic-106	30	10	the	the	DET
hjic-106	30	11	1990	1990	NUM
hjic-106	30	12	’s	’s	NOUN
hjic-106	30	13	.	.	PUNCT
hjic-106	31	1	[	[	X
hjic-106	31	2	12	12	NUM
hjic-106	31	3	]	]	PUNCT
hjic-106	31	4	the	the	DET
hjic-106	31	5	principle	principle	NOUN
hjic-106	31	6	of	of	ADP
hjic-106	31	7	the	the	DET
hjic-106	31	8	technique	technique	NOUN
hjic-106	31	9	has	have	AUX
hjic-106	31	10	been	be	AUX
hjic-106	31	11	described	describe	VERB
hjic-106	31	12	in	in	ADP
hjic-106	31	13	numerous	numerous	ADJ
hjic-106	31	14	publications	publication	NOUN
hjic-106	31	15	[	[	X
hjic-106	31	16	13	13	NUM
hjic-106	31	17	-	-	SYM
hjic-106	31	18	15	15	NUM
hjic-106	31	19	]	]	PUNCT
hjic-106	31	20	.	.	PUNCT
hjic-106	32	1	the	the	DET
hjic-106	32	2	essence	essence	NOUN
hjic-106	32	3	of	of	ADP
hjic-106	32	4	the	the	DET
hjic-106	32	5	process	process	NOUN
hjic-106	32	6	is	be	AUX
hjic-106	32	7	that	that	SCONJ
hjic-106	32	8	instead	instead	ADV
hjic-106	32	9	of	of	ADP
hjic-106	32	10	the	the	DET
hjic-106	32	11	continuous	continuous	ADJ
hjic-106	32	12	transportation	transportation	NOUN
hjic-106	32	13	of	of	ADP
hjic-106	32	14	the	the	DET
hjic-106	32	15	particulate	particulate	NOUN
hjic-106	32	16	solid	solid	ADJ
hjic-106	32	17	phase	phase	NOUN
hjic-106	32	18	,	,	PUNCT
hjic-106	32	19	which	which	PRON
hjic-106	32	20	leads	lead	VERB
hjic-106	32	21	to	to	ADP
hjic-106	32	22	a	a	DET
hjic-106	32	23	lot	lot	NOUN
hjic-106	32	24	of	of	ADP
hjic-106	32	25	difficulties	difficulty	NOUN
hjic-106	32	26	,	,	PUNCT
hjic-106	32	27	(	(	PUNCT
hjic-106	32	28	bad	bad	ADJ
hjic-106	32	29	efficiency	efficiency	NOUN
hjic-106	32	30	because	because	SCONJ
hjic-106	32	31	of	of	ADP
hjic-106	32	32	high	high	ADJ
hjic-106	32	33	hetp	hetp	NOUN
hjic-106	32	34	and	and	CCONJ
hjic-106	32	35	mechanic	mechanic	ADJ
hjic-106	32	36	problems	problem	NOUN
hjic-106	32	37	with	with	ADP
hjic-106	32	38	transportation	transportation	NOUN
hjic-106	32	39	of	of	ADP
hjic-106	32	40	the	the	DET
hjic-106	32	41	solid	solid	ADJ
hjic-106	32	42	phase	phase	NOUN
hjic-106	32	43	)	)	PUNCT
hjic-106	32	44	the	the	DET
hjic-106	32	45	moving	moving	NOUN
hjic-106	32	46	of	of	ADP
hjic-106	32	47	the	the	DET
hjic-106	32	48	solid	solid	ADJ
hjic-106	32	49	phase	phase	NOUN
hjic-106	32	50	in	in	ADP
hjic-106	32	51	packed	packed	ADJ
hjic-106	32	52	columns	column	NOUN
hjic-106	32	53	is	be	AUX
hjic-106	32	54	simulated	simulate	VERB
hjic-106	32	55	.	.	PUNCT
hjic-106	33	1	this	this	DET
hjic-106	33	2	simulated	simulated	ADJ
hjic-106	33	3	moving	moving	NOUN
hjic-106	33	4	can	can	AUX
hjic-106	33	5	be	be	AUX
hjic-106	33	6	solved	solve	VERB
hjic-106	33	7	either	either	CCONJ
hjic-106	33	8	by	by	ADP
hjic-106	33	9	switching	switch	VERB
hjic-106	33	10	the	the	DET
hjic-106	33	11	inlets	inlet	NOUN
hjic-106	33	12	and	and	CCONJ
hjic-106	33	13	outlets	outlet	NOUN
hjic-106	33	14	co	co	NOUN
hjic-106	33	15	-	-	NOUN
hjic-106	33	16	current	current	ADJ
hjic-106	33	17	with	with	ADP
hjic-106	33	18	the	the	DET
hjic-106	33	19	liquid	liquid	ADJ
hjic-106	33	20	flow	flow	NOUN
hjic-106	33	21	direction	direction	NOUN
hjic-106	33	22	,	,	PUNCT
hjic-106	33	23	or	or	CCONJ
hjic-106	33	24	by	by	ADP
hjic-106	33	25	the	the	DET
hjic-106	33	26	real	real	ADJ
hjic-106	33	27	rotation	rotation	NOUN
hjic-106	33	28	of	of	ADP
hjic-106	33	29	the	the	DET
hjic-106	33	30	packed	pack	VERB
hjic-106	33	31	columns	column	NOUN
hjic-106	33	32	,	,	PUNCT
hjic-106	33	33	connected	connect	VERB
hjic-106	33	34	to	to	ADP
hjic-106	33	35	special	special	ADJ
hjic-106	33	36	distributing	distribute	VERB
hjic-106	33	37	valves	valve	NOUN
hjic-106	33	38	.	.	PUNCT
hjic-106	34	1	(	(	PUNCT
hjic-106	34	2	fig	fig	NOUN
hjic-106	34	3	.	.	PUNCT
hjic-106	35	1	1	1	NUM
hjic-106	35	2	.	.	PUNCT
hjic-106	35	3	)	)	PUNCT
hjic-106	36	1	in	in	ADP
hjic-106	36	2	the	the	DET
hjic-106	36	3	smb	smb	NOUN
hjic-106	36	4	process	process	NOUN
hjic-106	36	5	the	the	PRON
hjic-106	36	6	strong	strong	ADJ
hjic-106	36	7	(	(	PUNCT
hjic-106	36	8	s	s	X
hjic-106	36	9	,	,	PUNCT
hjic-106	36	10	more	more	ADV
hjic-106	36	11	retained	retain	VERB
hjic-106	36	12	)	)	PUNCT
hjic-106	36	13	and	and	CCONJ
hjic-106	36	14	weak	weak	ADJ
hjic-106	36	15	(	(	PUNCT
hjic-106	36	16	w	w	NOUN
hjic-106	36	17	,	,	PUNCT
hjic-106	36	18	less	less	ADV
hjic-106	36	19	retained	retained	ADJ
hjic-106	36	20	)	)	PUNCT
hjic-106	36	21	components	component	NOUN
hjic-106	36	22	of	of	ADP
hjic-106	36	23	the	the	DET
hjic-106	36	24	feed	feed	NOUN
hjic-106	36	25	(	(	PUNCT
hjic-106	36	26	f	f	X
hjic-106	36	27	)	)	PUNCT
hjic-106	36	28	of	of	ADP
hjic-106	36	29	concentration	concentration	NOUN
hjic-106	36	30	cf	cf	NOUN
hjic-106	36	31	,	,	PUNCT
hjic-106	36	32	s	s	PART
hjic-106	36	33	and	and	CCONJ
hjic-106	36	34	cf	cf	NOUN
hjic-106	36	35	,	,	PUNCT
hjic-106	36	36	w	w	PROPN
hjic-106	36	37	are	be	AUX
hjic-106	36	38	separated	separate	VERB
hjic-106	36	39	into	into	ADP
hjic-106	36	40	two	two	NUM
hjic-106	36	41	outlet	outlet	NOUN
hjic-106	36	42	flows	flow	NOUN
hjic-106	36	43	.	.	PUNCT
hjic-106	37	1	in	in	ADP
hjic-106	37	2	the	the	DET
hjic-106	37	3	extract	extract	NOUN
hjic-106	37	4	(	(	PUNCT
hjic-106	37	5	e	e	NOUN
hjic-106	37	6	,	,	PUNCT
hjic-106	37	7	ce	ce	PROPN
hjic-106	37	8	,	,	PUNCT
hjic-106	37	9	s	s	PROPN
hjic-106	37	10	,	,	PUNCT
hjic-106	37	11	ce	ce	PROPN
hjic-106	37	12	,	,	PUNCT
hjic-106	37	13	w	w	PROPN
hjic-106	37	14	)	)	PUNCT
hjic-106	37	15	the	the	DET
hjic-106	37	16	better	well	ADV
hjic-106	37	17	adsorbing	adsorb	VERB
hjic-106	37	18	strong	strong	ADJ
hjic-106	37	19	,	,	PUNCT
hjic-106	37	20	while	while	SCONJ
hjic-106	37	21	in	in	SCONJ
hjic-106	37	22	the	the	DET
hjic-106	37	23	raffinate	raffinate	NOUN
hjic-106	37	24	(	(	PUNCT
hjic-106	37	25	r	r	NOUN
hjic-106	37	26	,	,	PUNCT
hjic-106	37	27	cr	cr	PROPN
hjic-106	37	28	,	,	PUNCT
hjic-106	37	29	s	s	PROPN
hjic-106	37	30	,	,	PUNCT
hjic-106	37	31	cr	cr	PROPN
hjic-106	37	32	,	,	PUNCT
hjic-106	37	33	w	w	PROPN
hjic-106	37	34	)	)	PUNCT
hjic-106	37	35	the	the	DET
hjic-106	37	36	less	less	ADV
hjic-106	37	37	adsorbing	adsorbing	ADJ
hjic-106	37	38	weak	weak	ADJ
hjic-106	37	39	components	component	NOUN
hjic-106	37	40	are	be	AUX
hjic-106	37	41	enriched	enrich	VERB
hjic-106	37	42	,	,	PUNCT
hjic-106	37	43	respectively	respectively	ADV
hjic-106	37	44	.	.	PUNCT
hjic-106	38	1	(	(	PUNCT
hjic-106	38	2	fig	fig	NOUN
hjic-106	38	3	.	.	PUNCT
hjic-106	39	1	2	2	NUM
hjic-106	39	2	.	.	PUNCT
hjic-106	39	3	)	)	PUNCT
hjic-106	40	1	in	in	ADP
hjic-106	40	2	purification	purification	NOUN
hjic-106	40	3	tasks	task	NOUN
hjic-106	40	4	there	there	PRON
hjic-106	40	5	are	be	VERB
hjic-106	40	6	usually	usually	ADV
hjic-106	40	7	one	one	NUM
hjic-106	40	8	(	(	PUNCT
hjic-106	40	9	or	or	CCONJ
hjic-106	40	10	some	some	PRON
hjic-106	40	11	more	more	ADJ
hjic-106	40	12	)	)	PUNCT
hjic-106	40	13	main	main	ADJ
hjic-106	40	14	compounds	compound	NOUN
hjic-106	40	15	in	in	ADP
hjic-106	40	16	the	the	DET
hjic-106	40	17	presence	presence	NOUN
hjic-106	40	18	of	of	ADP
hjic-106	40	19	numerous	numerous	ADJ
hjic-106	40	20	impurities	impurity	NOUN
hjic-106	40	21	of	of	ADP
hjic-106	40	22	small	small	ADJ
hjic-106	40	23	amount	amount	NOUN
hjic-106	40	24	.	.	PUNCT
hjic-106	41	1	in	in	ADP
hjic-106	41	2	such	such	ADJ
hjic-106	41	3	cases	case	NOUN
hjic-106	41	4	smb	smb	NOUN
hjic-106	41	5	is	be	AUX
hjic-106	41	6	generally	generally	ADV
hjic-106	41	7	not	not	PART
hjic-106	41	8	applicable	applicable	ADJ
hjic-106	41	9	,	,	PUNCT
hjic-106	41	10	mainly	mainly	ADV
hjic-106	41	11	preparative	preparative	ADJ
hjic-106	41	12	batch	batch	NOUN
hjic-106	41	13	elution	elution	NOUN
hjic-106	41	14	techniques	technique	NOUN
hjic-106	41	15	are	be	AUX
hjic-106	41	16	used	use	VERB
hjic-106	41	17	.	.	PUNCT
hjic-106	42	1	[	[	X
hjic-106	42	2	16	16	NUM
hjic-106	42	3	-	-	SYM
hjic-106	42	4	19	19	NUM
hjic-106	42	5	]	]	PUNCT
hjic-106	42	6	16	16	NUM
hjic-106	42	7	fig	fig	NOUN
hjic-106	42	8	.	.	PUNCT
hjic-106	43	1	1	1	NUM
hjic-106	43	2	:	:	PUNCT
hjic-106	43	3	conventional	conventional	ADJ
hjic-106	43	4	four	four	NUM
hjic-106	43	5	-	-	PUNCT
hjic-106	43	6	zone	zone	NOUN
hjic-106	43	7	smb	smb	NOUN
hjic-106	43	8	unit	unit	NOUN
hjic-106	43	9	with	with	ADP
hjic-106	43	10	eight	eight	NUM
hjic-106	43	11	columns	column	NOUN
hjic-106	43	12	the	the	DET
hjic-106	43	13	conventional	conventional	ADJ
hjic-106	43	14	smb	smb	PROPN
hjic-106	43	15	instrument	instrument	NOUN
hjic-106	43	16	set	set	NOUN
hjic-106	43	17	-	-	PUNCT
hjic-106	43	18	up	up	NOUN
hjic-106	43	19	can	can	AUX
hjic-106	43	20	be	be	AUX
hjic-106	43	21	utilized	utilize	VERB
hjic-106	43	22	to	to	PART
hjic-106	43	23	solve	solve	VERB
hjic-106	43	24	a	a	DET
hjic-106	43	25	batch	batch	NOUN
hjic-106	43	26	elution	elution	NOUN
hjic-106	43	27	chromatographic	chromatographic	ADJ
hjic-106	43	28	purification	purification	NOUN
hjic-106	43	29	task	task	NOUN
hjic-106	43	30	quasi	quasi	NOUN
hjic-106	43	31	-	-	PUNCT
hjic-106	43	32	continuously	continuously	ADV
hjic-106	43	33	,	,	PUNCT
hjic-106	43	34	if	if	SCONJ
hjic-106	43	35	an	an	DET
hjic-106	43	36	astute	astute	ADJ
hjic-106	43	37	assembling	assemble	VERB
hjic-106	43	38	mode	mode	NOUN
hjic-106	43	39	of	of	ADP
hjic-106	43	40	the	the	DET
hjic-106	43	41	available	available	ADJ
hjic-106	43	42	unit	unit	NOUN
hjic-106	43	43	is	be	AUX
hjic-106	43	44	applied	apply	VERB
hjic-106	43	45	.	.	PUNCT
hjic-106	44	1	in	in	ADP
hjic-106	44	2	this	this	DET
hjic-106	44	3	present	present	ADJ
hjic-106	44	4	study	study	NOUN
hjic-106	44	5	the	the	DET
hjic-106	44	6	quasi	quasi	ADJ
hjic-106	44	7	-	-	ADJ
hjic-106	44	8	continuous	continuous	ADJ
hjic-106	44	9	implementation	implementation	NOUN
hjic-106	44	10	of	of	ADP
hjic-106	44	11	a	a	DET
hjic-106	44	12	current	current	ADJ
hjic-106	44	13	pilot	pilot	NOUN
hjic-106	44	14	-	-	PUNCT
hjic-106	44	15	scale	scale	NOUN
hjic-106	44	16	batch	batch	NOUN
hjic-106	44	17	elution	elution	NOUN
hjic-106	44	18	purification	purification	NOUN
hjic-106	44	19	of	of	ADP
hjic-106	44	20	a	a	DET
hjic-106	44	21	steroid	steroid	NOUN
hjic-106	44	22	active	active	ADJ
hjic-106	44	23	compound	compound	NOUN
hjic-106	44	24	is	be	AUX
hjic-106	44	25	shown	show	VERB
hjic-106	44	26	.	.	PUNCT
hjic-106	45	1	the	the	DET
hjic-106	45	2	process	process	NOUN
hjic-106	45	3	consists	consist	VERB
hjic-106	45	4	of	of	ADP
hjic-106	45	5	the	the	DET
hjic-106	45	6	following	follow	VERB
hjic-106	45	7	steps	step	NOUN
hjic-106	45	8	:	:	PUNCT
hjic-106	45	9	(	(	PUNCT
hjic-106	45	10	1	1	NUM
hjic-106	45	11	.	.	PUNCT
hjic-106	45	12	)	)	PUNCT
hjic-106	46	1	injection	injection	NOUN
hjic-106	46	2	of	of	ADP
hjic-106	46	3	the	the	DET
hjic-106	46	4	crude	crude	ADJ
hjic-106	46	5	sample	sample	NOUN
hjic-106	46	6	solved	solve	VERB
hjic-106	46	7	in	in	ADP
hjic-106	46	8	the	the	DET
hjic-106	46	9	eluent	eluent	NOUN
hjic-106	46	10	onto	onto	ADP
hjic-106	46	11	the	the	DET
hjic-106	46	12	chromatographic	chromatographic	ADJ
hjic-106	46	13	column	column	NOUN
hjic-106	46	14	,	,	PUNCT
hjic-106	46	15	(	(	PUNCT
hjic-106	46	16	2	2	NUM
hjic-106	46	17	.	.	PUNCT
hjic-106	46	18	)	)	PUNCT
hjic-106	47	1	elution	elution	NOUN
hjic-106	47	2	of	of	ADP
hjic-106	47	3	the	the	DET
hjic-106	47	4	less	less	ADV
hjic-106	47	5	retained	retain	VERB
hjic-106	47	6	impurities	impurity	NOUN
hjic-106	47	7	with	with	ADP
hjic-106	47	8	the	the	DET
hjic-106	47	9	eluent	eluent	NOUN
hjic-106	47	10	,	,	PUNCT
hjic-106	47	11	(	(	PUNCT
hjic-106	47	12	3	3	NUM
hjic-106	47	13	.	.	PUNCT
hjic-106	47	14	)	)	PUNCT
hjic-106	48	1	elution	elution	NOUN
hjic-106	48	2	of	of	ADP
hjic-106	48	3	the	the	DET
hjic-106	48	4	pure	pure	ADJ
hjic-106	48	5	fraction	fraction	NOUN
hjic-106	48	6	of	of	ADP
hjic-106	48	7	the	the	DET
hjic-106	48	8	active	active	ADJ
hjic-106	48	9	compound	compound	NOUN
hjic-106	48	10	(	(	PUNCT
hjic-106	48	11	main	main	ADJ
hjic-106	48	12	fraction	fraction	NOUN
hjic-106	48	13	)	)	PUNCT
hjic-106	48	14	with	with	ADP
hjic-106	48	15	the	the	DET
hjic-106	48	16	eluent	eluent	NOUN
hjic-106	48	17	,	,	PUNCT
hjic-106	48	18	(	(	PUNCT
hjic-106	48	19	4	4	NUM
hjic-106	48	20	.	.	PUNCT
hjic-106	48	21	)	)	PUNCT
hjic-106	48	22	back	back	ADV
hjic-106	48	23	-	-	PUNCT
hjic-106	48	24	flushing	flush	VERB
hjic-106	48	25	the	the	DET
hjic-106	48	26	column	column	NOUN
hjic-106	48	27	with	with	ADP
hjic-106	48	28	the	the	DET
hjic-106	48	29	more	more	ADV
hjic-106	48	30	polar	polar	ADJ
hjic-106	48	31	solvent	solvent	ADJ
hjic-106	48	32	component	component	NOUN
hjic-106	48	33	of	of	ADP
hjic-106	48	34	the	the	DET
hjic-106	48	35	eluent	eluent	NOUN
hjic-106	48	36	to	to	PART
hjic-106	48	37	remove	remove	VERB
hjic-106	48	38	the	the	DET
hjic-106	48	39	strongly	strongly	ADV
hjic-106	48	40	retained	retain	VERB
hjic-106	48	41	compounds	compound	NOUN
hjic-106	48	42	,	,	PUNCT
hjic-106	48	43	(	(	PUNCT
hjic-106	48	44	5	5	NUM
hjic-106	48	45	.	.	PUNCT
hjic-106	48	46	)	)	PUNCT
hjic-106	49	1	conditioning	condition	VERB
hjic-106	49	2	the	the	DET
hjic-106	49	3	column	column	NOUN
hjic-106	49	4	with	with	ADP
hjic-106	49	5	the	the	DET
hjic-106	49	6	eluent	eluent	NOUN
hjic-106	49	7	to	to	PART
hjic-106	49	8	prepare	prepare	VERB
hjic-106	49	9	for	for	ADP
hjic-106	49	10	the	the	DET
hjic-106	49	11	next	next	ADJ
hjic-106	49	12	injection	injection	NOUN
hjic-106	49	13	.	.	PUNCT
hjic-106	50	1	the	the	DET
hjic-106	50	2	subsequent	subsequent	ADJ
hjic-106	50	3	steps	step	NOUN
hjic-106	50	4	can	can	AUX
hjic-106	50	5	be	be	AUX
hjic-106	50	6	carried	carry	VERB
hjic-106	50	7	out	out	ADP
hjic-106	50	8	in	in	ADP
hjic-106	50	9	parallel	parallel	NOUN
hjic-106	50	10	in	in	ADP
hjic-106	50	11	the	the	DET
hjic-106	50	12	zones	zone	NOUN
hjic-106	50	13	of	of	ADP
hjic-106	50	14	the	the	DET
hjic-106	50	15	smb	smb	PROPN
hjic-106	50	16	unit	unit	NOUN
hjic-106	50	17	,	,	PUNCT
hjic-106	50	18	which	which	PRON
hjic-106	50	19	are	be	AUX
hjic-106	50	20	independent	independent	ADJ
hjic-106	50	21	from	from	ADP
hjic-106	50	22	each	each	DET
hjic-106	50	23	other	other	ADJ
hjic-106	50	24	in	in	ADP
hjic-106	50	25	this	this	DET
hjic-106	50	26	special	special	ADJ
hjic-106	50	27	case	case	NOUN
hjic-106	50	28	.	.	PUNCT
hjic-106	51	1	the	the	DET
hjic-106	51	2	implementation	implementation	NOUN
hjic-106	51	3	of	of	ADP
hjic-106	51	4	quasi	quasi	ADJ
hjic-106	51	5	-	-	ADJ
hjic-106	51	6	continuous	continuous	ADJ
hjic-106	51	7	process	process	NOUN
hjic-106	51	8	starting	start	VERB
hjic-106	51	9	from	from	ADP
hjic-106	51	10	usual	usual	ADJ
hjic-106	51	11	smb	smb	NOUN
hjic-106	51	12	instrument	instrument	NOUN
hjic-106	51	13	set	set	NOUN
hjic-106	51	14	-	-	PUNCT
hjic-106	51	15	up	up	ADP
hjic-106	51	16	the	the	DET
hjic-106	51	17	conventional	conventional	ADJ
hjic-106	51	18	smb	smb	NOUN
hjic-106	51	19	unit	unit	NOUN
hjic-106	51	20	has	have	VERB
hjic-106	51	21	four	four	NUM
hjic-106	51	22	zones	zone	NOUN
hjic-106	51	23	as	as	SCONJ
hjic-106	51	24	can	can	AUX
hjic-106	51	25	be	be	AUX
hjic-106	51	26	seen	see	VERB
hjic-106	51	27	in	in	ADP
hjic-106	51	28	fig.1	fig.1	PROPN
hjic-106	51	29	.	.	PUNCT
hjic-106	52	1	and	and	CCONJ
hjic-106	52	2	fig.2	fig.2	PROPN
hjic-106	52	3	.	.	PUNCT
hjic-106	52	4	fig	fig	NOUN
hjic-106	52	5	.	.	PUNCT
hjic-106	53	1	2	2	NUM
hjic-106	53	2	.	.	X
hjic-106	53	3	:	:	PUNCT
hjic-106	54	1	one	one	NUM
hjic-106	54	2	of	of	ADP
hjic-106	54	3	the	the	DET
hjic-106	54	4	applied	apply	VERB
hjic-106	54	5	practical	practical	ADJ
hjic-106	54	6	solutions	solution	NOUN
hjic-106	54	7	of	of	ADP
hjic-106	54	8	the	the	DET
hjic-106	54	9	simulated	simulated	ADJ
hjic-106	54	10	moving	move	VERB
hjic-106	54	11	bed	bed	NOUN
hjic-106	54	12	it	it	PRON
hjic-106	54	13	is	be	AUX
hjic-106	54	14	possible	possible	ADJ
hjic-106	54	15	to	to	PART
hjic-106	54	16	carry	carry	VERB
hjic-106	54	17	out	out	ADP
hjic-106	54	18	the	the	DET
hjic-106	54	19	above	above	ADV
hjic-106	54	20	-	-	PUNCT
hjic-106	54	21	mentioned	mention	VERB
hjic-106	54	22	actual	actual	ADJ
hjic-106	54	23	five	five	NUM
hjic-106	54	24	-	-	PUNCT
hjic-106	54	25	step	step	NOUN
hjic-106	54	26	batch	batch	NOUN
hjic-106	54	27	elution	elution	NOUN
hjic-106	54	28	chromatographic	chromatographic	ADJ
hjic-106	54	29	purification	purification	NOUN
hjic-106	54	30	procedure	procedure	NOUN
hjic-106	54	31	quasi	quasi	NOUN
hjic-106	54	32	-	-	PUNCT
hjic-106	54	33	continuously	continuously	ADV
hjic-106	54	34	in	in	ADP
hjic-106	54	35	these	these	DET
hjic-106	54	36	zones	zone	NOUN
hjic-106	54	37	with	with	ADP
hjic-106	54	38	the	the	DET
hjic-106	54	39	help	help	NOUN
hjic-106	54	40	of	of	ADP
hjic-106	54	41	the	the	DET
hjic-106	54	42	rotating	rotate	VERB
hjic-106	54	43	switching	switching	NOUN
hjic-106	54	44	valve	valve	NOUN
hjic-106	54	45	of	of	ADP
hjic-106	54	46	the	the	DET
hjic-106	54	47	smb	smb	PROPN
hjic-106	54	48	instrument	instrument	NOUN
hjic-106	54	49	.	.	PUNCT
hjic-106	55	1	as	as	ADP
hjic-106	55	2	in	in	ADP
hjic-106	55	3	our	our	PRON
hjic-106	55	4	special	special	ADJ
hjic-106	55	5	case	case	NOUN
hjic-106	55	6	the	the	DET
hjic-106	55	7	zones	zone	NOUN
hjic-106	55	8	are	be	AUX
hjic-106	55	9	independent	independent	ADJ
hjic-106	55	10	from	from	ADP
hjic-106	55	11	each	each	DET
hjic-106	55	12	other	other	ADJ
hjic-106	55	13	,	,	PUNCT
hjic-106	55	14	they	they	PRON
hjic-106	55	15	can	can	AUX
hjic-106	55	16	be	be	AUX
hjic-106	55	17	decomposed	decompose	VERB
hjic-106	55	18	to	to	ADP
hjic-106	55	19	six	six	NUM
hjic-106	55	20	parts	part	NOUN
hjic-106	55	21	and	and	CCONJ
hjic-106	55	22	the	the	DET
hjic-106	55	23	flow	flow	NOUN
hjic-106	55	24	rate	rate	NOUN
hjic-106	55	25	can	can	AUX
hjic-106	55	26	be	be	AUX
hjic-106	55	27	reversed	reverse	VERB
hjic-106	55	28	in	in	ADP
hjic-106	55	29	zone	zone	PROPN
hjic-106	56	1	i	i	PRON
hjic-106	56	2	,	,	PUNCT
hjic-106	56	3	as	as	ADP
hjic-106	56	4	fig	fig	NOUN
hjic-106	56	5	.	.	PUNCT
hjic-106	57	1	3	3	NUM
hjic-106	57	2	shows	show	NOUN
hjic-106	57	3	.	.	PUNCT
hjic-106	58	1	fig	fig	NOUN
hjic-106	58	2	.	.	PUNCT
hjic-106	59	1	3	3	X
hjic-106	59	2	.	.	PUNCT
hjic-106	59	3	:	:	PUNCT
hjic-106	59	4	quasi	quasi	ADJ
hjic-106	59	5	-	-	ADJ
hjic-106	59	6	continuous	continuous	ADJ
hjic-106	59	7	operation	operation	NOUN
hjic-106	59	8	with	with	ADP
hjic-106	59	9	the	the	DET
hjic-106	59	10	help	help	NOUN
hjic-106	59	11	of	of	ADP
hjic-106	59	12	rotating	rotate	VERB
hjic-106	59	13	switching	switching	NOUN
hjic-106	59	14	valve	valve	NOUN
hjic-106	59	15	of	of	ADP
hjic-106	59	16	the	the	DET
hjic-106	59	17	smb	smb	PROPN
hjic-106	59	18	unit	unit	NOUN
hjic-106	59	19	the	the	DET
hjic-106	59	20	minimum	minimum	ADJ
hjic-106	59	21	number	number	NOUN
hjic-106	59	22	of	of	ADP
hjic-106	59	23	columns	column	NOUN
hjic-106	59	24	required	require	VERB
hjic-106	59	25	in	in	ADP
hjic-106	59	26	the	the	DET
hjic-106	59	27	process	process	NOUN
hjic-106	59	28	is	be	AUX
hjic-106	59	29	eight	eight	NUM
hjic-106	59	30	and	and	CCONJ
hjic-106	59	31	in	in	ADP
hjic-106	59	32	every	every	DET
hjic-106	59	33	second	second	ADJ
hjic-106	59	34	position	position	NOUN
hjic-106	59	35	an	an	DET
hjic-106	59	36	empty	empty	ADJ
hjic-106	59	37	short	short	ADJ
hjic-106	59	38	capillary	capillary	NOUN
hjic-106	59	39	is	be	AUX
hjic-106	59	40	inserted	insert	VERB
hjic-106	59	41	in	in	ADP
hjic-106	59	42	the	the	DET
hjic-106	59	43	unit	unit	NOUN
hjic-106	59	44	.	.	PUNCT
hjic-106	60	1	one	one	NUM
hjic-106	60	2	column	column	NOUN
hjic-106	60	3	and	and	CCONJ
hjic-106	60	4	one	one	NUM
hjic-106	60	5	empty	empty	ADJ
hjic-106	60	6	position	position	NOUN
hjic-106	60	7	move	move	VERB
hjic-106	60	8	together	together	ADV
hjic-106	60	9	to	to	ADP
hjic-106	60	10	the	the	DET
hjic-106	60	11	next	next	ADJ
hjic-106	60	12	position	position	NOUN
hjic-106	60	13	in	in	ADP
hjic-106	60	14	every	every	DET
hjic-106	60	15	switching	switching	NOUN
hjic-106	60	16	.	.	PUNCT
hjic-106	61	1	with	with	ADP
hjic-106	61	2	the	the	DET
hjic-106	61	3	knowledge	knowledge	NOUN
hjic-106	61	4	of	of	ADP
hjic-106	61	5	the	the	DET
hjic-106	61	6	solvent	solvent	ADJ
hjic-106	61	7	volumes	volume	NOUN
hjic-106	61	8	necessary	necessary	ADJ
hjic-106	61	9	to	to	ADP
hjic-106	61	10	the	the	DET
hjic-106	61	11	subsequent	subsequent	ADJ
hjic-106	61	12	steps	step	NOUN
hjic-106	61	13	of	of	ADP
hjic-106	61	14	the	the	DET
hjic-106	61	15	separation	separation	NOUN
hjic-106	61	16	,	,	PUNCT
hjic-106	61	17	the	the	DET
hjic-106	61	18	switching	switch	VERB
hjic-106	61	19	time	time	NOUN
hjic-106	61	20	of	of	ADP
hjic-106	61	21	the	the	DET
hjic-106	61	22	rotating	rotate	VERB
hjic-106	61	23	smb	smb	NOUN
hjic-106	61	24	valve	valve	NOUN
hjic-106	61	25	and	and	CCONJ
hjic-106	61	26	flow	flow	NOUN
hjic-106	61	27	rates	rate	NOUN
hjic-106	61	28	of	of	ADP
hjic-106	61	29	the	the	DET
hjic-106	61	30	pumps	pump	NOUN
hjic-106	61	31	in	in	ADP
hjic-106	61	32	the	the	DET
hjic-106	61	33	zones	zone	NOUN
hjic-106	61	34	can	can	AUX
hjic-106	61	35	be	be	AUX
hjic-106	61	36	calculated	calculate	VERB
hjic-106	61	37	.	.	PUNCT
hjic-106	62	1	the	the	DET
hjic-106	62	2	main	main	ADJ
hjic-106	62	3	steps	step	NOUN
hjic-106	62	4	of	of	ADP
hjic-106	62	5	the	the	DET
hjic-106	62	6	elaboration	elaboration	NOUN
hjic-106	62	7	of	of	ADP
hjic-106	62	8	the	the	DET
hjic-106	62	9	quasicontinuous	quasicontinuous	ADJ
hjic-106	62	10	process	process	NOUN
hjic-106	62	11	are	be	AUX
hjic-106	62	12	:	:	PUNCT
hjic-106	62	13	(	(	PUNCT
hjic-106	62	14	a.	a.	NOUN
hjic-106	62	15	)	)	PUNCT
hjic-106	62	16	preliminary	preliminary	ADJ
hjic-106	62	17	elution	elution	NOUN
hjic-106	62	18	experiment	experiment	NOUN
hjic-106	62	19	on	on	ADP
hjic-106	62	20	one	one	NUM
hjic-106	62	21	of	of	ADP
hjic-106	62	22	the	the	DET
hjic-106	62	23	eight	eight	NUM
hjic-106	62	24	250x16	250x16	NUM
hjic-106	62	25	mm	mm	PROPN
hjic-106	62	26	i.d	i.d	PROPN
hjic-106	62	27	.	.	PROPN
hjic-106	62	28	columns	column	NOUN
hjic-106	62	29	used	use	VERB
hjic-106	62	30	in	in	ADP
hjic-106	62	31	the	the	DET
hjic-106	62	32	smb	smb	PROPN
hjic-106	62	33	unit	unit	NOUN
hjic-106	62	34	for	for	ADP
hjic-106	62	35	quasi	quasi	ADJ
hjic-106	62	36	-	-	ADJ
hjic-106	62	37	continuous	continuous	ADJ
hjic-106	62	38	elution	elution	NOUN
hjic-106	62	39	separation	separation	NOUN
hjic-106	62	40	,	,	PUNCT
hjic-106	62	41	for	for	ADP
hjic-106	62	42	the	the	DET
hjic-106	62	43	determination	determination	NOUN
hjic-106	62	44	of	of	ADP
hjic-106	62	45	the	the	DET
hjic-106	62	46	solvent	solvent	ADJ
hjic-106	62	47	volumes	volume	NOUN
hjic-106	62	48	necessary	necessary	ADJ
hjic-106	62	49	to	to	ADP
hjic-106	62	50	the	the	DET
hjic-106	62	51	steps	step	NOUN
hjic-106	62	52	of	of	ADP
hjic-106	62	53	the	the	DET
hjic-106	62	54	separation	separation	NOUN
hjic-106	62	55	.	.	PUNCT
hjic-106	63	1	from	from	ADP
hjic-106	63	2	these	these	DET
hjic-106	63	3	data	datum	NOUN
hjic-106	63	4	the	the	DET
hjic-106	63	5	switching	switching	NOUN
hjic-106	63	6	time	time	NOUN
hjic-106	63	7	of	of	ADP
hjic-106	63	8	the	the	DET
hjic-106	63	9	rotating	rotate	VERB
hjic-106	63	10	smb	smb	NOUN
hjic-106	63	11	valve	valve	NOUN
hjic-106	63	12	and	and	CCONJ
hjic-106	63	13	the	the	DET
hjic-106	63	14	pump	pump	NOUN
hjic-106	63	15	flow	flow	NOUN
hjic-106	63	16	rates	rate	NOUN
hjic-106	63	17	can	can	AUX
hjic-106	63	18	be	be	AUX
hjic-106	63	19	calculated	calculate	VERB
hjic-106	63	20	.	.	PUNCT
hjic-106	64	1	(	(	PUNCT
hjic-106	64	2	b.	b.	NOUN
hjic-106	64	3	)	)	PUNCT
hjic-106	64	4	carrying	carry	VERB
hjic-106	64	5	out	out	ADP
hjic-106	64	6	a	a	DET
hjic-106	64	7	quasi	quasi	ADJ
hjic-106	64	8	-	-	ADJ
hjic-106	64	9	continuous	continuous	ADJ
hjic-106	64	10	experiment	experiment	NOUN
hjic-106	64	11	applying	apply	VERB
hjic-106	64	12	the	the	DET
hjic-106	64	13	calculated	calculated	ADJ
hjic-106	64	14	parameters	parameter	NOUN
hjic-106	64	15	.	.	PUNCT
hjic-106	65	1	(	(	PUNCT
hjic-106	65	2	c.	c.	NOUN
hjic-106	65	3	)	)	PUNCT
hjic-106	65	4	refining	refine	VERB
hjic-106	65	5	the	the	DET
hjic-106	65	6	process	process	NOUN
hjic-106	65	7	parameters	parameter	NOUN
hjic-106	65	8	in	in	ADP
hjic-106	65	9	experimental	experimental	ADJ
hjic-106	65	10	way	way	NOUN
hjic-106	65	11	.	.	PUNCT
hjic-106	66	1	(	(	PUNCT
hjic-106	66	2	d.	d.	NOUN
hjic-106	66	3	)	)	PUNCT
hjic-106	66	4	improvement	improvement	VERB
hjic-106	66	5	the	the	DET
hjic-106	66	6	productivity	productivity	NOUN
hjic-106	66	7	by	by	ADP
hjic-106	66	8	decreasing	decrease	VERB
hjic-106	66	9	the	the	DET
hjic-106	66	10	switching	switching	NOUN
hjic-106	66	11	time	time	NOUN
hjic-106	66	12	and	and	CCONJ
hjic-106	66	13	proportionally	proportionally	ADV
hjic-106	66	14	increasing	increase	VERB
hjic-106	66	15	the	the	DET
hjic-106	66	16	flow	flow	NOUN
hjic-106	66	17	rates	rate	NOUN
hjic-106	66	18	of	of	ADP
hjic-106	66	19	the	the	DET
hjic-106	66	20	pumps	pump	NOUN
hjic-106	66	21	at	at	ADP
hjic-106	66	22	the	the	DET
hjic-106	66	23	same	same	ADJ
hjic-106	66	24	time	time	NOUN
hjic-106	66	25	.	.	PUNCT
hjic-106	67	1	experimental	experimental	ADJ
hjic-106	67	2	the	the	DET
hjic-106	67	3	problem	problem	NOUN
hjic-106	67	4	under	under	ADP
hjic-106	67	5	investigation	investigation	NOUN
hjic-106	67	6	was	be	AUX
hjic-106	67	7	the	the	DET
hjic-106	67	8	solution	solution	NOUN
hjic-106	67	9	of	of	ADP
hjic-106	67	10	quasi	quasi	ADJ
hjic-106	67	11	-	-	ADJ
hjic-106	67	12	continuous	continuous	ADJ
hjic-106	67	13	elution	elution	NOUN
hjic-106	67	14	chromatographic	chromatographic	ADJ
hjic-106	67	15	purification	purification	NOUN
hjic-106	67	16	of	of	ADP
hjic-106	67	17	a	a	DET
hjic-106	67	18	steroid	steroid	NOUN
hjic-106	67	19	active	active	ADJ
hjic-106	67	20	compound	compound	NOUN
hjic-106	67	21	,	,	PUNCT
hjic-106	67	22	produced	produce	VERB
hjic-106	67	23	by	by	ADP
hjic-106	67	24	gedeon	gedeon	PROPN
hjic-106	67	25	richter	richter	PROPN
hjic-106	67	26	ltd	ltd	PROPN
hjic-106	67	27	.	.	PUNCT
hjic-106	68	1	the	the	DET
hjic-106	68	2	starting	starting	NOUN
hjic-106	68	3	point	point	NOUN
hjic-106	68	4	of	of	ADP
hjic-106	68	5	the	the	DET
hjic-106	68	6	investigation	investigation	NOUN
hjic-106	68	7	was	be	AUX
hjic-106	68	8	the	the	DET
hjic-106	68	9	pilot	pilot	NOUN
hjic-106	68	10	-	-	PUNCT
hjic-106	68	11	plant	plant	NOUN
hjic-106	68	12	batch	batch	NOUN
hjic-106	68	13	elution	elution	NOUN
hjic-106	68	14	chromatographic	chromatographic	ADJ
hjic-106	68	15	separation	separation	NOUN
hjic-106	68	16	of	of	ADP
hjic-106	68	17	the	the	DET
hjic-106	68	18	compound	compound	NOUN
hjic-106	68	19	from	from	ADP
hjic-106	68	20	its	its	PRON
hjic-106	68	21	impurities	impurity	NOUN
hjic-106	68	22	,	,	PUNCT
hjic-106	68	23	followed	follow	VERB
hjic-106	68	24	by	by	ADP
hjic-106	68	25	a	a	DET
hjic-106	68	26	crystallisation	crystallisation	NOUN
hjic-106	68	27	step	step	NOUN
hjic-106	68	28	(	(	PUNCT
hjic-106	68	29	not	not	PART
hjic-106	68	30	published	publish	VERB
hjic-106	68	31	here	here	ADV
hjic-106	68	32	)	)	PUNCT
hjic-106	68	33	.	.	PUNCT
hjic-106	69	1	this	this	DET
hjic-106	69	2	procedure	procedure	NOUN
hjic-106	69	3	has	have	AUX
hjic-106	69	4	been	be	AUX
hjic-106	69	5	applied	apply	VERB
hjic-106	69	6	successfully	successfully	ADV
hjic-106	69	7	for	for	ADP
hjic-106	69	8	years	year	NOUN
hjic-106	69	9	.	.	PUNCT
hjic-106	70	1	the	the	DET
hjic-106	70	2	purity	purity	NOUN
hjic-106	70	3	of	of	ADP
hjic-106	70	4	the	the	DET
hjic-106	70	5	crude	crude	ADJ
hjic-106	70	6	material	material	NOUN
hjic-106	70	7	was	be	AUX
hjic-106	70	8	94	94	NUM
hjic-106	70	9	%	%	NOUN
hjic-106	70	10	for	for	ADP
hjic-106	70	11	the	the	DET
hjic-106	70	12	active	active	ADJ
hjic-106	70	13	compound	compound	NOUN
hjic-106	70	14	.	.	PUNCT
hjic-106	71	1	the	the	DET
hjic-106	71	2	goal	goal	NOUN
hjic-106	71	3	was	be	AUX
hjic-106	71	4	to	to	PART
hjic-106	71	5	produce	produce	VERB
hjic-106	71	6	the	the	DET
hjic-106	71	7	active	active	ADJ
hjic-106	71	8	compound	compound	NOUN
hjic-106	71	9	with	with	ADP
hjic-106	71	10	a	a	DET
hjic-106	71	11	purity	purity	NOUN
hjic-106	71	12	of	of	ADP
hjic-106	71	13	>	>	PROPN
hjic-106	71	14	99	99	NUM
hjic-106	71	15	%	%	NOUN
hjic-106	71	16	,	,	PUNCT
hjic-106	71	17	the	the	DET
hjic-106	71	18	maximum	maximum	ADJ
hjic-106	71	19	level	level	NOUN
hjic-106	71	20	of	of	ADP
hjic-106	71	21	individual	individual	ADJ
hjic-106	71	22	impurities	impurity	NOUN
hjic-106	71	23	had	have	VERB
hjic-106	71	24	to	to	PART
hjic-106	71	25	be	be	AUX
hjic-106	71	26	under	under	ADP
hjic-106	71	27	0.3	0.3	NUM
hjic-106	71	28	%	%	NOUN
hjic-106	71	29	.	.	PUNCT
hjic-106	72	1	17	17	NUM
hjic-106	72	2	chemicals	chemical	NOUN
hjic-106	72	3	uetikon	uetikon	NOUN
hjic-106	72	4	c-490	c-490	VERB
hjic-106	72	5	15	15	NUM
hjic-106	72	6	-	-	SYM
hjic-106	72	7	35	35	NUM
hjic-106	72	8	μm	μm	NOUN
hjic-106	72	9	si	si	NOUN
hjic-106	72	10	gel	gel	NOUN
hjic-106	72	11	was	be	AUX
hjic-106	72	12	used	use	VERB
hjic-106	72	13	as	as	ADP
hjic-106	72	14	the	the	DET
hjic-106	72	15	stationary	stationary	ADJ
hjic-106	72	16	phase	phase	NOUN
hjic-106	72	17	,	,	PUNCT
hjic-106	72	18	it	it	PRON
hjic-106	72	19	was	be	AUX
hjic-106	72	20	purchased	purchase	VERB
hjic-106	72	21	from	from	ADP
hjic-106	72	22	zeochem	zeochem	PROPN
hjic-106	72	23	ag	ag	PROPN
hjic-106	72	24	(	(	PUNCT
hjic-106	72	25	switzerland	switzerland	PROPN
hjic-106	72	26	)	)	PUNCT
hjic-106	72	27	.	.	PUNCT
hjic-106	73	1	the	the	DET
hjic-106	73	2	mobile	mobile	ADJ
hjic-106	73	3	phase	phase	NOUN
hjic-106	73	4	was	be	AUX
hjic-106	73	5	methylene	methylene	ADJ
hjic-106	73	6	chloride	chloride	NOUN
hjic-106	73	7	/	/	SYM
hjic-106	73	8	ethyl	ethyl	PROPN
hjic-106	73	9	acetate	acetate	NOUN
hjic-106	73	10	mixture	mixture	NOUN
hjic-106	73	11	.	.	PUNCT
hjic-106	74	1	the	the	DET
hjic-106	74	2	back	back	ADV
hjic-106	74	3	-	-	PUNCT
hjic-106	74	4	flushing	flush	VERB
hjic-106	74	5	solvent	solvent	NOUN
hjic-106	74	6	was	be	AUX
hjic-106	74	7	pure	pure	ADJ
hjic-106	74	8	ethyl	ethyl	PROPN
hjic-106	74	9	acetate	acetate	NOUN
hjic-106	74	10	.	.	PUNCT
hjic-106	75	1	solvents	solvent	NOUN
hjic-106	75	2	were	be	AUX
hjic-106	75	3	purchased	purchase	VERB
hjic-106	75	4	from	from	ADP
hjic-106	75	5	merck	merck	PROPN
hjic-106	75	6	kgaa	kgaa	PROPN
hjic-106	75	7	(	(	PUNCT
hjic-106	75	8	darmstadt	darmstadt	PROPN
hjic-106	75	9	,	,	PUNCT
hjic-106	75	10	germany	germany	PROPN
hjic-106	75	11	)	)	PUNCT
hjic-106	75	12	.	.	PUNCT
hjic-106	76	1	instrumentation	instrumentation	NOUN
hjic-106	76	2	preliminary	preliminary	ADJ
hjic-106	76	3	elution	elution	NOUN
hjic-106	76	4	experiment	experiment	NOUN
hjic-106	76	5	the	the	DET
hjic-106	76	6	applied	apply	VERB
hjic-106	76	7	instrument	instrument	NOUN
hjic-106	76	8	consisted	consist	VERB
hjic-106	76	9	of	of	ADP
hjic-106	76	10	a	a	DET
hjic-106	76	11	knauer	knauer	NOUN
hjic-106	76	12	k-501	k-501	PROPN
hjic-106	76	13	hplc	hplc	PROPN
hjic-106	76	14	pump	pump	NOUN
hjic-106	76	15	,	,	PUNCT
hjic-106	76	16	the	the	DET
hjic-106	76	17	volumetric	volumetric	NOUN
hjic-106	76	18	flow	flow	NOUN
hjic-106	76	19	rate	rate	NOUN
hjic-106	76	20	was	be	AUX
hjic-106	76	21	set	set	VERB
hjic-106	76	22	to	to	ADP
hjic-106	76	23	5	5	NUM
hjic-106	76	24	ml	ml	NOUN
hjic-106	76	25	min-1	min-1	NOUN
hjic-106	76	26	,	,	PUNCT
hjic-106	76	27	one	one	NUM
hjic-106	76	28	of	of	ADP
hjic-106	76	29	the	the	DET
hjic-106	76	30	eight	eight	NUM
hjic-106	76	31	250x16	250x16	NUM
hjic-106	76	32	mm	mm	PROPN
hjic-106	76	33	i.d	i.d	PROPN
hjic-106	76	34	.	.	PROPN
hjic-106	76	35	columns	column	NOUN
hjic-106	76	36	used	use	VERB
hjic-106	76	37	in	in	ADP
hjic-106	76	38	the	the	DET
hjic-106	76	39	smb	smb	PROPN
hjic-106	76	40	unit	unit	NOUN
hjic-106	76	41	for	for	ADP
hjic-106	76	42	quasi	quasi	ADJ
hjic-106	76	43	-	-	ADJ
hjic-106	76	44	continuous	continuous	ADJ
hjic-106	76	45	elution	elution	NOUN
hjic-106	76	46	separation	separation	NOUN
hjic-106	76	47	,	,	PUNCT
hjic-106	76	48	packed	pack	VERB
hjic-106	76	49	with	with	ADP
hjic-106	76	50	uetikon	uetikon	PROPN
hjic-106	76	51	c-490	c-490	VERB
hjic-106	76	52	15	15	NUM
hjic-106	76	53	-	-	SYM
hjic-106	76	54	35	35	NUM
hjic-106	76	55	μm	μm	NOUN
hjic-106	76	56	si	si	NOUN
hjic-106	76	57	gel	gel	NOUN
hjic-106	76	58	packing	packing	NOUN
hjic-106	76	59	material	material	NOUN
hjic-106	76	60	in	in	ADP
hjic-106	76	61	our	our	PRON
hjic-106	76	62	laboratory	laboratory	NOUN
hjic-106	76	63	by	by	ADP
hjic-106	76	64	dry	dry	ADJ
hjic-106	76	65	-	-	PUNCT
hjic-106	76	66	packing	pack	VERB
hjic-106	76	67	method	method	NOUN
hjic-106	76	68	using	use	VERB
hjic-106	76	69	vibration	vibration	NOUN
hjic-106	76	70	,	,	PUNCT
hjic-106	76	71	and	and	CCONJ
hjic-106	76	72	a	a	DET
hjic-106	76	73	knauer	knauer	NOUN
hjic-106	76	74	uv	uv	NOUN
hjic-106	76	75	/	/	SYM
hjic-106	76	76	vis	vis	X
hjic-106	76	77	filter	filter	NOUN
hjic-106	76	78	photometer	photometer	NOUN
hjic-106	76	79	.	.	PUNCT
hjic-106	77	1	the	the	DET
hjic-106	77	2	wavelength	wavelength	NOUN
hjic-106	77	3	of	of	ADP
hjic-106	77	4	the	the	DET
hjic-106	77	5	measurement	measurement	NOUN
hjic-106	77	6	was	be	AUX
hjic-106	77	7	254	254	NUM
hjic-106	77	8	nm	nm	NOUN
hjic-106	77	9	.	.	PUNCT
hjic-106	78	1	for	for	ADP
hjic-106	78	2	the	the	DET
hjic-106	78	3	purpose	purpose	NOUN
hjic-106	78	4	of	of	ADP
hjic-106	78	5	recording	record	VERB
hjic-106	78	6	the	the	DET
hjic-106	78	7	chromatogram	chromatogram	NOUN
hjic-106	78	8	a	a	DET
hjic-106	78	9	radelkis	radelki	NOUN
hjic-106	78	10	oh-850	oh-850	DET
hjic-106	78	11	potentiometric	potentiometric	ADJ
hjic-106	78	12	recorder	recorder	NOUN
hjic-106	78	13	was	be	AUX
hjic-106	78	14	applied	apply	VERB
hjic-106	78	15	.	.	PUNCT
hjic-106	79	1	the	the	DET
hjic-106	79	2	temperature	temperature	NOUN
hjic-106	79	3	was	be	AUX
hjic-106	79	4	set	set	VERB
hjic-106	79	5	to	to	ADP
hjic-106	79	6	25	25	NUM
hjic-106	79	7	˚c	˚c	PROPN
hjic-106	79	8	.	.	PUNCT
hjic-106	80	1	quasi	quasi	ADJ
hjic-106	80	2	-	-	ADJ
hjic-106	80	3	continuous	continuous	ADJ
hjic-106	80	4	experiments	experiment	NOUN
hjic-106	80	5	a	a	DET
hjic-106	80	6	laboratory	laboratory	NOUN
hjic-106	80	7	-	-	PUNCT
hjic-106	80	8	scale	scale	NOUN
hjic-106	80	9	smb	smb	NOUN
hjic-106	80	10	unit	unit	NOUN
hjic-106	80	11	(	(	PUNCT
hjic-106	80	12	knauer	knauer	PROPN
hjic-106	80	13	csep	csep	PROPN
hjic-106	80	14	9116	9116	NUM
hjic-106	80	15	)	)	PUNCT
hjic-106	80	16	was	be	AUX
hjic-106	80	17	used	use	VERB
hjic-106	80	18	for	for	ADP
hjic-106	80	19	the	the	DET
hjic-106	80	20	quasi	quasi	ADJ
hjic-106	80	21	-	-	ADJ
hjic-106	80	22	continuous	continuous	ADJ
hjic-106	80	23	elution	elution	NOUN
hjic-106	80	24	experiments	experiment	NOUN
hjic-106	80	25	with	with	ADP
hjic-106	80	26	five	five	NUM
hjic-106	80	27	knauer	knauer	NOUN
hjic-106	80	28	k-501	k-501	NOUN
hjic-106	80	29	hplc	hplc	PROPN
hjic-106	80	30	pumps	pump	NOUN
hjic-106	80	31	and	and	CCONJ
hjic-106	80	32	eight	eight	NUM
hjic-106	80	33	columns	column	NOUN
hjic-106	80	34	.	.	PUNCT
hjic-106	81	1	the	the	DET
hjic-106	81	2	columns	column	NOUN
hjic-106	81	3	were	be	AUX
hjic-106	81	4	packed	pack	VERB
hjic-106	81	5	in	in	ADP
hjic-106	81	6	our	our	PRON
hjic-106	81	7	laboratory	laboratory	NOUN
hjic-106	81	8	by	by	ADP
hjic-106	81	9	dry	dry	ADJ
hjic-106	81	10	-	-	PUNCT
hjic-106	81	11	packing	pack	VERB
hjic-106	81	12	method	method	NOUN
hjic-106	81	13	,	,	PUNCT
hjic-106	81	14	using	use	VERB
hjic-106	81	15	vibration	vibration	NOUN
hjic-106	81	16	,	,	PUNCT
hjic-106	81	17	as	as	SCONJ
hjic-106	81	18	we	we	PRON
hjic-106	81	19	described	describe	VERB
hjic-106	81	20	above	above	ADV
hjic-106	81	21	.	.	PUNCT
hjic-106	82	1	(	(	PUNCT
hjic-106	82	2	column	column	NOUN
hjic-106	82	3	dimension	dimension	NOUN
hjic-106	82	4	was	be	AUX
hjic-106	82	5	250x16	250x16	NUM
hjic-106	82	6	mm	mm	PROPN
hjic-106	82	7	i.d	i.d	PROPN
hjic-106	82	8	.	.	PROPN
hjic-106	82	9	)	)	PUNCT
hjic-106	82	10	.	.	PUNCT
hjic-106	83	1	the	the	DET
hjic-106	83	2	uniformity	uniformity	NOUN
hjic-106	83	3	of	of	ADP
hjic-106	83	4	columns	column	NOUN
hjic-106	83	5	was	be	AUX
hjic-106	83	6	tested	test	VERB
hjic-106	83	7	by	by	ADP
hjic-106	83	8	elution	elution	NOUN
hjic-106	83	9	investigations	investigation	NOUN
hjic-106	83	10	,	,	PUNCT
hjic-106	83	11	injecting	inject	VERB
hjic-106	83	12	pure	pure	ADJ
hjic-106	83	13	active	active	ADJ
hjic-106	83	14	compound	compound	NOUN
hjic-106	83	15	on	on	ADP
hjic-106	83	16	the	the	DET
hjic-106	83	17	columns	column	NOUN
hjic-106	83	18	and	and	CCONJ
hjic-106	83	19	eluting	elute	VERB
hjic-106	83	20	it	it	PRON
hjic-106	83	21	with	with	ADP
hjic-106	83	22	the	the	DET
hjic-106	83	23	eluent	eluent	NOUN
hjic-106	83	24	.	.	PUNCT
hjic-106	84	1	in	in	ADP
hjic-106	84	2	the	the	DET
hjic-106	84	3	zone	zone	NOUN
hjic-106	84	4	of	of	ADP
hjic-106	84	5	the	the	DET
hjic-106	84	6	pure	pure	ADJ
hjic-106	84	7	main	main	ADJ
hjic-106	84	8	fraction	fraction	NOUN
hjic-106	84	9	a	a	DET
hjic-106	84	10	knauer	knauer	NOUN
hjic-106	84	11	uv	uv	NOUN
hjic-106	84	12	/	/	SYM
hjic-106	84	13	vis	vis	X
hjic-106	84	14	filter	filter	NOUN
hjic-106	84	15	photometer	photometer	NOUN
hjic-106	84	16	was	be	AUX
hjic-106	84	17	connected	connect	VERB
hjic-106	84	18	.	.	PUNCT
hjic-106	85	1	the	the	DET
hjic-106	85	2	wavelength	wavelength	NOUN
hjic-106	85	3	was	be	AUX
hjic-106	85	4	set	set	VERB
hjic-106	85	5	to	to	ADP
hjic-106	85	6	254	254	NUM
hjic-106	85	7	nm	nm	NOUN
hjic-106	85	8	.	.	PUNCT
hjic-106	86	1	for	for	ADP
hjic-106	86	2	the	the	DET
hjic-106	86	3	purpose	purpose	NOUN
hjic-106	86	4	of	of	ADP
hjic-106	86	5	recording	record	VERB
hjic-106	86	6	the	the	DET
hjic-106	86	7	successive	successive	ADJ
hjic-106	86	8	chromatograms	chromatogram	NOUN
hjic-106	86	9	a	a	DET
hjic-106	86	10	radelkis	radelki	NOUN
hjic-106	86	11	oh-850	oh-850	DET
hjic-106	86	12	potentiometric	potentiometric	ADJ
hjic-106	86	13	recorder	recorder	NOUN
hjic-106	86	14	was	be	AUX
hjic-106	86	15	applied	apply	VERB
hjic-106	86	16	.	.	PUNCT
hjic-106	87	1	the	the	DET
hjic-106	87	2	temperature	temperature	NOUN
hjic-106	87	3	was	be	AUX
hjic-106	87	4	set	set	VERB
hjic-106	87	5	to	to	ADP
hjic-106	87	6	25	25	NUM
hjic-106	87	7	˚c	˚c	NOUN
hjic-106	87	8	.	.	PUNCT
hjic-106	88	1	(	(	PUNCT
hjic-106	88	2	see	see	VERB
hjic-106	88	3	fig	fig	NOUN
hjic-106	88	4	.	.	PUNCT
hjic-106	89	1	4	4	NUM
hjic-106	89	2	.	.	NUM
hjic-106	89	3	)	)	PUNCT
hjic-106	89	4	fig	fig	NOUN
hjic-106	89	5	.	.	PUNCT
hjic-106	90	1	4	4	X
hjic-106	90	2	.	.	NUM
hjic-106	90	3	:	:	PUNCT
hjic-106	91	1	knauer	knauer	PROPN
hjic-106	91	2	csep	csep	PROPN
hjic-106	91	3	9116	9116	NUM
hjic-106	91	4	smb	smb	PROPN
hjic-106	91	5	unit	unit	NOUN
hjic-106	91	6	assembled	assemble	VERB
hjic-106	91	7	for	for	ADP
hjic-106	91	8	quasi	quasi	ADJ
hjic-106	91	9	-	-	ADJ
hjic-106	91	10	continuous	continuous	ADJ
hjic-106	91	11	process	process	NOUN
hjic-106	91	12	analytical	analytical	ADJ
hjic-106	91	13	method	method	NOUN
hjic-106	91	14	applied	apply	VERB
hjic-106	91	15	for	for	ADP
hjic-106	91	16	the	the	DET
hjic-106	91	17	quality	quality	NOUN
hjic-106	91	18	control	control	NOUN
hjic-106	91	19	of	of	ADP
hjic-106	91	20	the	the	DET
hjic-106	91	21	separation	separation	NOUN
hjic-106	91	22	the	the	DET
hjic-106	91	23	quality	quality	NOUN
hjic-106	91	24	control	control	NOUN
hjic-106	91	25	of	of	ADP
hjic-106	91	26	the	the	DET
hjic-106	91	27	purified	purified	ADJ
hjic-106	91	28	active	active	ADJ
hjic-106	91	29	compound	compound	NOUN
hjic-106	91	30	was	be	AUX
hjic-106	91	31	performed	perform	VERB
hjic-106	91	32	by	by	ADP
hjic-106	91	33	a	a	DET
hjic-106	91	34	validated	validate	VERB
hjic-106	91	35	analytical	analytical	ADJ
hjic-106	91	36	chromatographic	chromatographic	ADJ
hjic-106	91	37	method	method	NOUN
hjic-106	91	38	,	,	PUNCT
hjic-106	91	39	which	which	PRON
hjic-106	91	40	is	be	AUX
hjic-106	91	41	applied	apply	VERB
hjic-106	91	42	for	for	ADP
hjic-106	91	43	the	the	DET
hjic-106	91	44	time	time	NOUN
hjic-106	91	45	being	be	AUX
hjic-106	91	46	in	in	ADP
hjic-106	91	47	the	the	DET
hjic-106	91	48	current	current	ADJ
hjic-106	91	49	manufacturing	manufacturing	NOUN
hjic-106	91	50	process	process	NOUN
hjic-106	91	51	of	of	ADP
hjic-106	91	52	the	the	DET
hjic-106	91	53	product	product	NOUN
hjic-106	91	54	.	.	PUNCT
hjic-106	92	1	preliminary	preliminary	ADJ
hjic-106	92	2	elution	elution	NOUN
hjic-106	92	3	experiment	experiment	NOUN
hjic-106	92	4	before	before	ADP
hjic-106	92	5	beginning	begin	VERB
hjic-106	92	6	the	the	DET
hjic-106	92	7	experiment	experiment	NOUN
hjic-106	92	8	,	,	PUNCT
hjic-106	92	9	the	the	DET
hjic-106	92	10	column	column	NOUN
hjic-106	92	11	was	be	AUX
hjic-106	92	12	equilibrated	equilibrate	VERB
hjic-106	92	13	with	with	ADP
hjic-106	92	14	the	the	DET
hjic-106	92	15	eluent	eluent	NOUN
hjic-106	92	16	.	.	PUNCT
hjic-106	93	1	the	the	DET
hjic-106	93	2	injected	inject	VERB
hjic-106	93	3	sample	sample	NOUN
hjic-106	93	4	amount	amount	NOUN
hjic-106	93	5	was	be	AUX
hjic-106	93	6	0.32	0.32	NUM
hjic-106	93	7	g	g	NOUN
hjic-106	93	8	of	of	ADP
hjic-106	93	9	crude	crude	ADJ
hjic-106	93	10	material	material	NOUN
hjic-106	93	11	,	,	PUNCT
hjic-106	93	12	which	which	PRON
hjic-106	93	13	was	be	AUX
hjic-106	93	14	solved	solve	VERB
hjic-106	93	15	in	in	ADP
hjic-106	93	16	5	5	NUM
hjic-106	93	17	ml	ml	ADP
hjic-106	93	18	methylene	methylene	NOUN
hjic-106	93	19	-	-	PUNCT
hjic-106	93	20	chloride	chloride	NOUN
hjic-106	93	21	.	.	PUNCT
hjic-106	94	1	after	after	ADP
hjic-106	94	2	the	the	DET
hjic-106	94	3	injection	injection	NOUN
hjic-106	94	4	step	step	NOUN
hjic-106	94	5	,	,	PUNCT
hjic-106	94	6	the	the	DET
hjic-106	94	7	elution	elution	NOUN
hjic-106	94	8	of	of	ADP
hjic-106	94	9	less	less	ADJ
hjic-106	94	10	retained	retain	VERB
hjic-106	94	11	impurities	impurity	NOUN
hjic-106	94	12	was	be	AUX
hjic-106	94	13	started	start	VERB
hjic-106	94	14	and	and	CCONJ
hjic-106	94	15	seven	seven	NUM
hjic-106	94	16	fractions	fraction	NOUN
hjic-106	94	17	were	be	AUX
hjic-106	94	18	collected	collect	VERB
hjic-106	94	19	,	,	PUNCT
hjic-106	94	20	for	for	ADP
hjic-106	94	21	the	the	DET
hjic-106	94	22	purpose	purpose	NOUN
hjic-106	94	23	of	of	ADP
hjic-106	94	24	determination	determination	NOUN
hjic-106	94	25	of	of	ADP
hjic-106	94	26	the	the	DET
hjic-106	94	27	first	first	ADJ
hjic-106	94	28	cut	cut	NOUN
hjic-106	94	29	point	point	NOUN
hjic-106	94	30	of	of	ADP
hjic-106	94	31	the	the	DET
hjic-106	94	32	pure	pure	ADJ
hjic-106	94	33	main	main	ADJ
hjic-106	94	34	fraction	fraction	NOUN
hjic-106	94	35	.	.	PUNCT
hjic-106	95	1	the	the	DET
hjic-106	95	2	end	end	NOUN
hjic-106	95	3	cut	cut	NOUN
hjic-106	95	4	point	point	NOUN
hjic-106	95	5	of	of	ADP
hjic-106	95	6	the	the	DET
hjic-106	95	7	peak	peak	NOUN
hjic-106	95	8	was	be	AUX
hjic-106	95	9	not	not	PART
hjic-106	95	10	so	so	ADV
hjic-106	95	11	critical	critical	ADJ
hjic-106	95	12	,	,	PUNCT
hjic-106	95	13	because	because	SCONJ
hjic-106	95	14	a	a	DET
hjic-106	95	15	certain	certain	ADJ
hjic-106	95	16	impurity	impurity	NOUN
hjic-106	95	17	of	of	ADP
hjic-106	95	18	small	small	ADJ
hjic-106	95	19	amount	amount	NOUN
hjic-106	95	20	,	,	PUNCT
hjic-106	95	21	eluting	elute	VERB
hjic-106	95	22	in	in	ADP
hjic-106	95	23	the	the	DET
hjic-106	95	24	tail	tail	NOUN
hjic-106	95	25	of	of	ADP
hjic-106	95	26	the	the	DET
hjic-106	95	27	active	active	ADJ
hjic-106	95	28	compound	compound	NOUN
hjic-106	95	29	peak	peak	NOUN
hjic-106	95	30	can	can	AUX
hjic-106	95	31	be	be	AUX
hjic-106	95	32	removed	remove	VERB
hjic-106	95	33	by	by	ADP
hjic-106	95	34	the	the	DET
hjic-106	95	35	crystallization	crystallization	NOUN
hjic-106	95	36	step	step	NOUN
hjic-106	95	37	,	,	PUNCT
hjic-106	95	38	following	follow	VERB
hjic-106	95	39	the	the	DET
hjic-106	95	40	chromatography	chromatography	NOUN
hjic-106	95	41	.	.	PUNCT
hjic-106	96	1	that	that	PRON
hjic-106	96	2	was	be	AUX
hjic-106	96	3	the	the	DET
hjic-106	96	4	reason	reason	NOUN
hjic-106	96	5	,	,	PUNCT
hjic-106	96	6	why	why	SCONJ
hjic-106	96	7	there	there	PRON
hjic-106	96	8	was	be	VERB
hjic-106	96	9	no	no	DET
hjic-106	96	10	fraction	fraction	NOUN
hjic-106	96	11	collection	collection	NOUN
hjic-106	96	12	there	there	ADV
hjic-106	96	13	.	.	PUNCT
hjic-106	97	1	fig	fig	NOUN
hjic-106	97	2	.	.	PUNCT
hjic-106	98	1	5	5	NUM
hjic-106	98	2	.	.	PUNCT
hjic-106	98	3	:	:	PUNCT
hjic-106	99	1	chromatogram	chromatogram	PROPN
hjic-106	99	2	of	of	ADP
hjic-106	99	3	the	the	DET
hjic-106	99	4	preliminary	preliminary	ADJ
hjic-106	99	5	elution	elution	NOUN
hjic-106	99	6	experiment	experiment	NOUN
hjic-106	99	7	when	when	SCONJ
hjic-106	99	8	the	the	DET
hjic-106	99	9	elution	elution	NOUN
hjic-106	99	10	of	of	ADP
hjic-106	99	11	the	the	DET
hjic-106	99	12	main	main	ADJ
hjic-106	99	13	compound	compound	NOUN
hjic-106	99	14	was	be	AUX
hjic-106	99	15	finished	finish	VERB
hjic-106	99	16	,	,	PUNCT
hjic-106	99	17	the	the	DET
hjic-106	99	18	back	back	ADV
hjic-106	99	19	-	-	PUNCT
hjic-106	99	20	flushing	flush	VERB
hjic-106	99	21	with	with	ADP
hjic-106	99	22	ethyl	ethyl	PROPN
hjic-106	99	23	acetate	acetate	PROPN
hjic-106	99	24	was	be	AUX
hjic-106	99	25	started	start	VERB
hjic-106	99	26	and	and	CCONJ
hjic-106	99	27	continued	continue	VERB
hjic-106	99	28	until	until	SCONJ
hjic-106	99	29	a	a	DET
hjic-106	99	30	stable	stable	ADJ
hjic-106	99	31	baseline	baseline	NOUN
hjic-106	99	32	was	be	AUX
hjic-106	99	33	achieved	achieve	VERB
hjic-106	99	34	.	.	PUNCT
hjic-106	100	1	at	at	ADP
hjic-106	100	2	the	the	DET
hjic-106	100	3	end	end	NOUN
hjic-106	100	4	of	of	ADP
hjic-106	100	5	the	the	DET
hjic-106	100	6	back	back	ADV
hjic-106	100	7	-	-	PUNCT
hjic-106	100	8	flushing	flush	VERB
hjic-106	100	9	,	,	PUNCT
hjic-106	100	10	the	the	DET
hjic-106	100	11	column	column	NOUN
hjic-106	100	12	conditioning	conditioning	NOUN
hjic-106	100	13	was	be	AUX
hjic-106	100	14	carried	carry	VERB
hjic-106	100	15	out	out	ADP
hjic-106	100	16	with	with	ADP
hjic-106	100	17	twice	twice	DET
hjic-106	100	18	of	of	ADP
hjic-106	100	19	the	the	DET
hjic-106	100	20	column	column	NOUN
hjic-106	100	21	volume	volume	NOUN
hjic-106	100	22	of	of	ADP
hjic-106	100	23	the	the	DET
hjic-106	100	24	eluent	eluent	NOUN
hjic-106	100	25	.	.	PUNCT
hjic-106	101	1	based	base	VERB
hjic-106	101	2	on	on	ADP
hjic-106	101	3	the	the	DET
hjic-106	101	4	pump	pump	NOUN
hjic-106	101	5	flow	flow	NOUN
hjic-106	101	6	rate	rate	NOUN
hjic-106	101	7	and	and	CCONJ
hjic-106	101	8	speed	speed	NOUN
hjic-106	101	9	of	of	ADP
hjic-106	101	10	the	the	DET
hjic-106	101	11	recorder	recorder	NOUN
hjic-106	101	12	,	,	PUNCT
hjic-106	101	13	the	the	DET
hjic-106	101	14	solvent	solvent	NOUN
hjic-106	101	15	volumes	volume	NOUN
hjic-106	101	16	,	,	PUNCT
hjic-106	101	17	necessary	necessary	ADJ
hjic-106	101	18	to	to	ADP
hjic-106	101	19	the	the	DET
hjic-106	101	20	subsequent	subsequent	ADJ
hjic-106	101	21	steps	step	NOUN
hjic-106	101	22	of	of	ADP
hjic-106	101	23	the	the	DET
hjic-106	101	24	separation	separation	NOUN
hjic-106	101	25	could	could	AUX
hjic-106	101	26	be	be	AUX
hjic-106	101	27	calculated	calculate	VERB
hjic-106	101	28	.	.	PUNCT
hjic-106	102	1	(	(	PUNCT
hjic-106	102	2	fig.5	fig.5	PROPN
hjic-106	102	3	.	.	PUNCT
hjic-106	102	4	)	)	PUNCT
hjic-106	103	1	quasi	quasi	ADJ
hjic-106	103	2	-	-	ADJ
hjic-106	103	3	continuous	continuous	ADJ
hjic-106	103	4	elution	elution	NOUN
hjic-106	103	5	experiments	experiment	NOUN
hjic-106	103	6	the	the	DET
hjic-106	103	7	switching	switch	VERB
hjic-106	103	8	time	time	NOUN
hjic-106	103	9	of	of	ADP
hjic-106	103	10	the	the	DET
hjic-106	103	11	rotating	rotate	VERB
hjic-106	103	12	smb	smb	NOUN
hjic-106	103	13	valve	valve	NOUN
hjic-106	103	14	was	be	AUX
hjic-106	103	15	calculated	calculate	VERB
hjic-106	103	16	based	base	VERB
hjic-106	103	17	on	on	ADP
hjic-106	103	18	the	the	DET
hjic-106	103	19	critical	critical	ADJ
hjic-106	103	20	data	datum	NOUN
hjic-106	103	21	of	of	ADP
hjic-106	103	22	the	the	DET
hjic-106	103	23	preliminary	preliminary	ADJ
hjic-106	103	24	elution	elution	NOUN
hjic-106	103	25	experiment	experiment	NOUN
hjic-106	103	26	,	,	PUNCT
hjic-106	103	27	such	such	ADJ
hjic-106	103	28	as	as	ADP
hjic-106	103	29	the	the	DET
hjic-106	103	30	elution	elution	NOUN
hjic-106	103	31	volumes	volume	NOUN
hjic-106	103	32	of	of	ADP
hjic-106	103	33	less	less	ADV
hjic-106	103	34	retained	retain	VERB
hjic-106	103	35	impurities	impurity	NOUN
hjic-106	103	36	and	and	CCONJ
hjic-106	103	37	the	the	DET
hjic-106	103	38	pure	pure	ADJ
hjic-106	103	39	active	active	ADJ
hjic-106	103	40	compound	compound	NOUN
hjic-106	103	41	.	.	PUNCT
hjic-106	104	1	(	(	PUNCT
hjic-106	104	2	see	see	VERB
hjic-106	104	3	table	table	NOUN
hjic-106	104	4	1	1	NUM
hjic-106	104	5	.	.	PUNCT
hjic-106	104	6	)	)	PUNCT
hjic-106	105	1	the	the	DET
hjic-106	105	2	pump	pump	NOUN
hjic-106	105	3	flow	flow	NOUN
hjic-106	105	4	rates	rate	NOUN
hjic-106	105	5	were	be	AUX
hjic-106	105	6	set	set	VERB
hjic-106	105	7	in	in	ADP
hjic-106	105	8	accordance	accordance	NOUN
hjic-106	105	9	with	with	ADP
hjic-106	105	10	the	the	DET
hjic-106	105	11	calculated	calculate	VERB
hjic-106	105	12	switching	switching	NOUN
hjic-106	105	13	time	time	NOUN
hjic-106	105	14	and	and	CCONJ
hjic-106	105	15	the	the	DET
hjic-106	105	16	solvent	solvent	ADJ
hjic-106	105	17	volumes	volume	NOUN
hjic-106	105	18	,	,	PUNCT
hjic-106	105	19	necessary	necessary	ADJ
hjic-106	105	20	to	to	ADP
hjic-106	105	21	the	the	DET
hjic-106	105	22	steps	step	NOUN
hjic-106	105	23	of	of	ADP
hjic-106	105	24	the	the	DET
hjic-106	105	25	separation	separation	NOUN
hjic-106	105	26	.	.	PUNCT
hjic-106	106	1	18	18	NUM
hjic-106	106	2	table	table	NOUN
hjic-106	106	3	1	1	NUM
hjic-106	106	4	:	:	PUNCT
hjic-106	106	5	results	result	NOUN
hjic-106	106	6	of	of	ADP
hjic-106	106	7	the	the	DET
hjic-106	106	8	preliminary	preliminary	ADJ
hjic-106	106	9	elution	elution	NOUN
hjic-106	106	10	experiment	experiment	NOUN
hjic-106	106	11	steps	step	NOUN
hjic-106	106	12	of	of	ADP
hjic-106	106	13	the	the	DET
hjic-106	106	14	separation	separation	NOUN
hjic-106	106	15	solvent	solvent	NOUN
hjic-106	106	16	volumes	volume	NOUN
hjic-106	106	17	necessary	necessary	ADJ
hjic-106	106	18	to	to	ADP
hjic-106	106	19	the	the	DET
hjic-106	106	20	subsequent	subsequent	ADJ
hjic-106	106	21	steps	step	NOUN
hjic-106	106	22	of	of	ADP
hjic-106	106	23	the	the	DET
hjic-106	106	24	separation	separation	NOUN
hjic-106	106	25	(	(	PUNCT
hjic-106	106	26	ml	ml	NOUN
hjic-106	106	27	)	)	PUNCT
hjic-106	106	28	elution	elution	NOUN
hjic-106	106	29	of	of	ADP
hjic-106	106	30	less	less	ADJ
hjic-106	106	31	retained	retain	VERB
hjic-106	106	32	impurities	impurity	NOUN
hjic-106	106	33	≈105	≈105	NOUN
hjic-106	106	34	elution	elution	NOUN
hjic-106	106	35	of	of	ADP
hjic-106	106	36	the	the	DET
hjic-106	106	37	pure	pure	ADJ
hjic-106	106	38	active	active	ADJ
hjic-106	106	39	compound	compound	NOUN
hjic-106	106	40	≈84	≈84	NOUN
hjic-106	106	41	back	back	ADV
hjic-106	106	42	-	-	PUNCT
hjic-106	106	43	flushing	flush	VERB
hjic-106	106	44	with	with	ADP
hjic-106	106	45	ethyl	ethyl	PROPN
hjic-106	106	46	acetate	acetate	PROPN
hjic-106	106	47	minimum	minimum	PROPN
hjic-106	106	48	65	65	NUM
hjic-106	106	49	column	column	NOUN
hjic-106	106	50	conditioning	conditioning	NOUN
hjic-106	106	51	twice	twice	ADV
hjic-106	106	52	of	of	ADP
hjic-106	106	53	the	the	DET
hjic-106	106	54	column	column	NOUN
hjic-106	106	55	volume	volume	NOUN
hjic-106	106	56	,	,	PUNCT
hjic-106	106	57	minimum	minimum	NOUN
hjic-106	106	58	100	100	NUM
hjic-106	106	59	the	the	DET
hjic-106	106	60	crude	crude	ADJ
hjic-106	106	61	sample	sample	NOUN
hjic-106	106	62	was	be	AUX
hjic-106	106	63	solved	solve	VERB
hjic-106	106	64	in	in	ADP
hjic-106	106	65	methylene	methylene	NOUN
hjic-106	106	66	-	-	PUNCT
hjic-106	106	67	chloride	chloride	NOUN
hjic-106	106	68	,	,	PUNCT
hjic-106	106	69	which	which	PRON
hjic-106	106	70	was	be	AUX
hjic-106	106	71	the	the	DET
hjic-106	106	72	weaker	weak	ADJ
hjic-106	106	73	solvent	solvent	ADJ
hjic-106	106	74	component	component	NOUN
hjic-106	106	75	of	of	ADP
hjic-106	106	76	the	the	DET
hjic-106	106	77	eluent	eluent	NOUN
hjic-106	106	78	.	.	PUNCT
hjic-106	107	1	the	the	DET
hjic-106	107	2	compounds	compound	NOUN
hjic-106	107	3	were	be	AUX
hjic-106	107	4	adsorbed	adsorb	VERB
hjic-106	107	5	on	on	ADP
hjic-106	107	6	the	the	DET
hjic-106	107	7	surface	surface	NOUN
hjic-106	107	8	of	of	ADP
hjic-106	107	9	packing	packing	NOUN
hjic-106	107	10	material	material	NOUN
hjic-106	107	11	from	from	ADP
hjic-106	107	12	this	this	DET
hjic-106	107	13	solution	solution	NOUN
hjic-106	107	14	in	in	ADP
hjic-106	107	15	a	a	DET
hjic-106	107	16	narrow	narrow	ADJ
hjic-106	107	17	band	band	NOUN
hjic-106	107	18	at	at	ADP
hjic-106	107	19	the	the	DET
hjic-106	107	20	beginning	beginning	NOUN
hjic-106	107	21	of	of	ADP
hjic-106	107	22	the	the	DET
hjic-106	107	23	columns	column	NOUN
hjic-106	107	24	,	,	PUNCT
hjic-106	107	25	therefore	therefore	ADV
hjic-106	107	26	the	the	DET
hjic-106	107	27	injected	inject	VERB
hjic-106	107	28	sample	sample	NOUN
hjic-106	107	29	volume	volume	NOUN
hjic-106	107	30	could	could	AUX
hjic-106	107	31	be	be	AUX
hjic-106	107	32	higher	high	ADJ
hjic-106	107	33	,	,	PUNCT
hjic-106	107	34	in	in	ADP
hjic-106	107	35	most	most	ADJ
hjic-106	107	36	cases	case	NOUN
hjic-106	107	37	exactly	exactly	ADV
hjic-106	107	38	10.5	10.5	NUM
hjic-106	107	39	ml	ml	NOUN
hjic-106	107	40	.	.	PUNCT
hjic-106	108	1	in	in	ADP
hjic-106	108	2	this	this	DET
hjic-106	108	3	case	case	NOUN
hjic-106	108	4	the	the	DET
hjic-106	108	5	sample	sample	NOUN
hjic-106	108	6	pump	pump	NOUN
hjic-106	108	7	(	(	PUNCT
hjic-106	108	8	p1	p1	NOUN
hjic-106	108	9	)	)	PUNCT
hjic-106	108	10	flow	flow	NOUN
hjic-106	108	11	rate	rate	NOUN
hjic-106	108	12	was	be	AUX
hjic-106	108	13	set	set	VERB
hjic-106	108	14	to	to	ADP
hjic-106	108	15	0.5	0.5	NUM
hjic-106	108	16	ml	ml	NOUN
hjic-106	108	17	min-1	min-1	PROPN
hjic-106	108	18	,	,	PUNCT
hjic-106	108	19	which	which	PRON
hjic-106	108	20	was	be	AUX
hjic-106	108	21	a	a	DET
hjic-106	108	22	reasonable	reasonable	ADJ
hjic-106	108	23	value	value	NOUN
hjic-106	108	24	.	.	PUNCT
hjic-106	109	1	in	in	ADP
hjic-106	109	2	the	the	DET
hjic-106	109	3	quasi	quasi	ADJ
hjic-106	109	4	-	-	ADJ
hjic-106	109	5	continuous	continuous	ADJ
hjic-106	109	6	experiments	experiment	NOUN
hjic-106	109	7	the	the	DET
hjic-106	109	8	sample	sample	NOUN
hjic-106	109	9	load	load	NOUN
hjic-106	109	10	was	be	AUX
hjic-106	109	11	the	the	DET
hjic-106	109	12	same	same	ADJ
hjic-106	109	13	as	as	ADP
hjic-106	109	14	in	in	ADP
hjic-106	109	15	the	the	DET
hjic-106	109	16	preliminary	preliminary	ADJ
hjic-106	109	17	elution	elution	NOUN
hjic-106	109	18	experiment	experiment	NOUN
hjic-106	109	19	,	,	PUNCT
hjic-106	109	20	namely	namely	ADV
hjic-106	109	21	0.32	0.32	NUM
hjic-106	109	22	g	g	NOUN
hjic-106	109	23	of	of	ADP
hjic-106	109	24	crude	crude	ADJ
hjic-106	109	25	material	material	NOUN
hjic-106	109	26	.	.	PUNCT
hjic-106	110	1	the	the	DET
hjic-106	110	2	exception	exception	NOUN
hjic-106	110	3	was	be	AUX
hjic-106	110	4	only	only	ADV
hjic-106	110	5	the	the	DET
hjic-106	110	6	second	second	ADJ
hjic-106	110	7	experiment	experiment	NOUN
hjic-106	110	8	,	,	PUNCT
hjic-106	110	9	in	in	ADP
hjic-106	110	10	which	which	PRON
hjic-106	110	11	the	the	DET
hjic-106	110	12	sample	sample	NOUN
hjic-106	110	13	load	load	NOUN
hjic-106	110	14	was	be	AUX
hjic-106	110	15	lower	low	ADJ
hjic-106	110	16	,	,	PUNCT
hjic-106	110	17	exactly	exactly	ADV
hjic-106	110	18	0.29	0.29	NUM
hjic-106	110	19	g	g	NOUN
hjic-106	110	20	of	of	ADP
hjic-106	110	21	crude	crude	ADJ
hjic-106	110	22	material	material	NOUN
hjic-106	110	23	.	.	PUNCT
hjic-106	111	1	the	the	DET
hjic-106	111	2	process	process	NOUN
hjic-106	111	3	parameters	parameter	NOUN
hjic-106	111	4	of	of	ADP
hjic-106	111	5	the	the	DET
hjic-106	111	6	experiments	experiment	NOUN
hjic-106	111	7	are	be	AUX
hjic-106	111	8	summarized	summarize	VERB
hjic-106	111	9	in	in	ADP
hjic-106	111	10	table	table	NOUN
hjic-106	111	11	2	2	NUM
hjic-106	111	12	.	.	PUNCT
hjic-106	111	13	table	table	NOUN
hjic-106	111	14	2	2	NUM
hjic-106	111	15	:	:	PUNCT
hjic-106	111	16	process	process	NOUN
hjic-106	111	17	parameters	parameter	NOUN
hjic-106	111	18	of	of	ADP
hjic-106	111	19	quasi	quasi	ADJ
hjic-106	111	20	-	-	ADJ
hjic-106	111	21	continuous	continuous	ADJ
hjic-106	111	22	elution	elution	NOUN
hjic-106	111	23	experiments	experiment	NOUN
hjic-106	111	24	flow	flow	NOUN
hjic-106	111	25	rates	rate	NOUN
hjic-106	111	26	of	of	ADP
hjic-106	111	27	the	the	DET
hjic-106	111	28	pumps	pump	NOUN
hjic-106	111	29	(	(	PUNCT
hjic-106	111	30	ml	ml	NOUN
hjic-106	111	31	min-1	min-1	NOUN
hjic-106	111	32	)	)	PUNCT
hjic-106	111	33	experiment	experiment	NOUN
hjic-106	111	34	switching	switch	VERB
hjic-106	111	35	time	time	NOUN
hjic-106	111	36	(	(	PUNCT
hjic-106	111	37	min	min	NOUN
hjic-106	111	38	)	)	PUNCT
hjic-106	111	39	sample	sample	NOUN
hjic-106	112	1	injection	injection	NOUN
hjic-106	112	2	p1	p1	NOUN
hjic-106	112	3	elution	elution	NOUN
hjic-106	112	4	of	of	ADP
hjic-106	112	5	less	less	ADJ
hjic-106	112	6	retained	retain	VERB
hjic-106	112	7	impurities	impurity	NOUN
hjic-106	112	8	p5	p5	ADJ
hjic-106	112	9	elution	elution	NOUN
hjic-106	112	10	of	of	ADP
hjic-106	112	11	the	the	DET
hjic-106	112	12	pure	pure	ADJ
hjic-106	112	13	active	active	ADJ
hjic-106	112	14	compound	compound	NOUN
hjic-106	112	15	p4	p4	ADJ
hjic-106	112	16	backflushing	backflushe	VERB
hjic-106	112	17	p2	p2	NOUN
hjic-106	112	18	column	column	NOUN
hjic-106	112	19	conditioning	condition	VERB
hjic-106	112	20	p3	p3	PROPN
hjic-106	112	21	1	1	NUM
hjic-106	112	22	.	.	NUM
hjic-106	112	23	21	21	NUM
hjic-106	112	24	0.5	0.5	NUM
hjic-106	112	25	5	5	NUM
hjic-106	112	26	4	4	NUM
hjic-106	112	27	4	4	NUM
hjic-106	112	28	3	3	NUM
hjic-106	112	29	2	2	NUM
hjic-106	112	30	.	.	NOUN
hjic-106	112	31	19	19	NUM
hjic-106	112	32	0.5	0.5	NUM
hjic-106	112	33	5	5	NUM
hjic-106	112	34	4	4	NUM
hjic-106	112	35	4	4	NUM
hjic-106	112	36	3	3	NUM
hjic-106	112	37	3	3	NUM
hjic-106	112	38	.	.	NOUN
hjic-106	112	39	21	21	NUM
hjic-106	112	40	0.5	0.5	NUM
hjic-106	112	41	4.7	4.7	NUM
hjic-106	112	42	4	4	NUM
hjic-106	112	43	4	4	NUM
hjic-106	112	44	3	3	NUM
hjic-106	112	45	4	4	NUM
hjic-106	112	46	.	.	PUNCT
hjic-106	112	47	21	21	NUM
hjic-106	112	48	0.5	0.5	NUM
hjic-106	112	49	4.5	4.5	NUM
hjic-106	112	50	2.5	2.5	NUM
hjic-106	112	51	4	4	NUM
hjic-106	112	52	3	3	NUM
hjic-106	112	53	5	5	NUM
hjic-106	112	54	.	.	SYM
hjic-106	113	1	21	21	NUM
hjic-106	113	2	0.5	0.5	NUM
hjic-106	113	3	4.5	4.5	NUM
hjic-106	113	4	3.2	3.2	NUM
hjic-106	113	5	4	4	NUM
hjic-106	113	6	3	3	NUM
hjic-106	113	7	6	6	NUM
hjic-106	113	8	.	.	SYM
hjic-106	113	9	21	21	NUM
hjic-106	113	10	0.5	0.5	NUM
hjic-106	113	11	4.5	4.5	NUM
hjic-106	113	12	3.5	3.5	NUM
hjic-106	113	13	4	4	NUM
hjic-106	113	14	3	3	NUM
hjic-106	113	15	7	7	NUM
hjic-106	113	16	.	.	SYM
hjic-106	113	17	21	21	NUM
hjic-106	113	18	0.5	0.5	NUM
hjic-106	113	19	4.5	4.5	NUM
hjic-106	113	20	3.5	3.5	NUM
hjic-106	113	21	4	4	NUM
hjic-106	113	22	3	3	NUM
hjic-106	113	23	8	8	NUM
hjic-106	113	24	.	.	PUNCT
hjic-106	113	25	14	14	NUM
hjic-106	113	26	0.75	0.75	NUM
hjic-106	113	27	6.75	6.75	NUM
hjic-106	113	28	5.2	5.2	NUM
hjic-106	113	29	6	6	NUM
hjic-106	113	30	4.5	4.5	NUM
hjic-106	113	31	results	result	NOUN
hjic-106	113	32	and	and	CCONJ
hjic-106	113	33	discussion	discussion	NOUN
hjic-106	113	34	results	result	NOUN
hjic-106	113	35	of	of	ADP
hjic-106	113	36	the	the	DET
hjic-106	113	37	preliminary	preliminary	ADJ
hjic-106	113	38	elution	elution	NOUN
hjic-106	113	39	experiment	experiment	NOUN
hjic-106	113	40	the	the	DET
hjic-106	113	41	aim	aim	NOUN
hjic-106	113	42	of	of	ADP
hjic-106	113	43	this	this	DET
hjic-106	113	44	experiment	experiment	NOUN
hjic-106	113	45	was	be	AUX
hjic-106	113	46	to	to	PART
hjic-106	113	47	determine	determine	VERB
hjic-106	113	48	the	the	DET
hjic-106	113	49	solvent	solvent	ADJ
hjic-106	113	50	volumes	volume	NOUN
hjic-106	113	51	necessary	necessary	ADJ
hjic-106	113	52	to	to	ADP
hjic-106	113	53	the	the	DET
hjic-106	113	54	steps	step	NOUN
hjic-106	113	55	of	of	ADP
hjic-106	113	56	the	the	DET
hjic-106	113	57	separation	separation	NOUN
hjic-106	113	58	.	.	PUNCT
hjic-106	114	1	the	the	DET
hjic-106	114	2	received	receive	VERB
hjic-106	114	3	data	datum	NOUN
hjic-106	114	4	can	can	AUX
hjic-106	114	5	be	be	AUX
hjic-106	114	6	seen	see	VERB
hjic-106	114	7	in	in	ADP
hjic-106	114	8	table	table	NOUN
hjic-106	114	9	1	1	NUM
hjic-106	114	10	.	.	PUNCT
hjic-106	114	11	elaboration	elaboration	NOUN
hjic-106	114	12	and	and	CCONJ
hjic-106	114	13	intensification	intensification	NOUN
hjic-106	114	14	of	of	ADP
hjic-106	114	15	the	the	DET
hjic-106	114	16	quasicontinuous	quasicontinuous	ADJ
hjic-106	114	17	process	process	NOUN
hjic-106	114	18	as	as	SCONJ
hjic-106	114	19	we	we	PRON
hjic-106	114	20	mentioned	mention	VERB
hjic-106	114	21	before	before	ADV
hjic-106	114	22	,	,	PUNCT
hjic-106	114	23	based	base	VERB
hjic-106	114	24	on	on	ADP
hjic-106	114	25	the	the	DET
hjic-106	114	26	critical	critical	ADJ
hjic-106	114	27	data	datum	NOUN
hjic-106	114	28	of	of	ADP
hjic-106	114	29	the	the	DET
hjic-106	114	30	preliminary	preliminary	ADJ
hjic-106	114	31	elution	elution	NOUN
hjic-106	114	32	experiment	experiment	NOUN
hjic-106	114	33	,	,	PUNCT
hjic-106	114	34	such	such	ADJ
hjic-106	114	35	as	as	ADP
hjic-106	114	36	the	the	DET
hjic-106	114	37	elution	elution	NOUN
hjic-106	114	38	volumes	volume	NOUN
hjic-106	114	39	of	of	ADP
hjic-106	114	40	less	less	ADV
hjic-106	114	41	retained	retain	VERB
hjic-106	114	42	impurities	impurity	NOUN
hjic-106	114	43	and	and	CCONJ
hjic-106	114	44	the	the	DET
hjic-106	114	45	pure	pure	ADJ
hjic-106	114	46	active	active	ADJ
hjic-106	114	47	compound	compound	NOUN
hjic-106	114	48	,	,	PUNCT
hjic-106	114	49	(	(	PUNCT
hjic-106	114	50	table	table	NOUN
hjic-106	114	51	1	1	NUM
hjic-106	114	52	.	.	PUNCT
hjic-106	114	53	)	)	PUNCT
hjic-106	115	1	the	the	DET
hjic-106	115	2	applied	apply	VERB
hjic-106	115	3	switching	switching	NOUN
hjic-106	115	4	time	time	NOUN
hjic-106	115	5	was	be	AUX
hjic-106	115	6	21	21	NUM
hjic-106	115	7	min	min	NOUN
hjic-106	115	8	in	in	ADP
hjic-106	115	9	the	the	DET
hjic-106	115	10	first	first	ADJ
hjic-106	115	11	experiment	experiment	NOUN
hjic-106	115	12	.	.	PUNCT
hjic-106	116	1	in	in	ADP
hjic-106	116	2	this	this	DET
hjic-106	116	3	first	first	ADJ
hjic-106	116	4	run	run	NOUN
hjic-106	116	5	the	the	DET
hjic-106	116	6	purity	purity	NOUN
hjic-106	116	7	was	be	AUX
hjic-106	116	8	very	very	ADV
hjic-106	116	9	good	good	ADJ
hjic-106	116	10	,	,	PUNCT
hjic-106	116	11	but	but	CCONJ
hjic-106	116	12	the	the	DET
hjic-106	116	13	recovery	recovery	NOUN
hjic-106	116	14	was	be	AUX
hjic-106	116	15	poor	poor	ADJ
hjic-106	116	16	,	,	PUNCT
hjic-106	116	17	because	because	SCONJ
hjic-106	116	18	a	a	DET
hjic-106	116	19	significant	significant	ADJ
hjic-106	116	20	part	part	NOUN
hjic-106	116	21	of	of	ADP
hjic-106	116	22	the	the	DET
hjic-106	116	23	main	main	ADJ
hjic-106	116	24	fraction	fraction	NOUN
hjic-106	116	25	eluted	elute	VERB
hjic-106	116	26	in	in	ADP
hjic-106	116	27	the	the	DET
hjic-106	116	28	zone	zone	NOUN
hjic-106	116	29	of	of	ADP
hjic-106	116	30	the	the	DET
hjic-106	116	31	less	less	ADV
hjic-106	116	32	retained	retain	VERB
hjic-106	116	33	impurities	impurity	NOUN
hjic-106	116	34	.	.	PUNCT
hjic-106	117	1	the	the	DET
hjic-106	117	2	reason	reason	NOUN
hjic-106	117	3	of	of	ADP
hjic-106	117	4	the	the	DET
hjic-106	117	5	deviation	deviation	NOUN
hjic-106	117	6	between	between	ADP
hjic-106	117	7	the	the	DET
hjic-106	117	8	preliminary	preliminary	ADJ
hjic-106	117	9	elution	elution	NOUN
hjic-106	117	10	experiment	experiment	NOUN
hjic-106	117	11	and	and	CCONJ
hjic-106	117	12	the	the	DET
hjic-106	117	13	first	first	ADJ
hjic-106	117	14	quasi	quasi	ADJ
hjic-106	117	15	-	-	ADJ
hjic-106	117	16	continuous	continuous	ADJ
hjic-106	117	17	run	run	NOUN
hjic-106	117	18	was	be	AUX
hjic-106	117	19	the	the	DET
hjic-106	117	20	difference	difference	NOUN
hjic-106	117	21	of	of	ADP
hjic-106	117	22	the	the	DET
hjic-106	117	23	extra	extra	ADJ
hjic-106	117	24	column	column	NOUN
hjic-106	117	25	volumes	volume	NOUN
hjic-106	117	26	of	of	ADP
hjic-106	117	27	the	the	DET
hjic-106	117	28	two	two	NUM
hjic-106	117	29	systems	system	NOUN
hjic-106	117	30	in	in	ADP
hjic-106	117	31	which	which	PRON
hjic-106	117	32	the	the	DET
hjic-106	117	33	experiments	experiment	NOUN
hjic-106	117	34	were	be	AUX
hjic-106	117	35	carried	carry	VERB
hjic-106	117	36	out	out	ADP
hjic-106	117	37	.	.	PUNCT
hjic-106	118	1	to	to	PART
hjic-106	118	2	improve	improve	VERB
hjic-106	118	3	the	the	DET
hjic-106	118	4	result	result	NOUN
hjic-106	118	5	of	of	ADP
hjic-106	118	6	the	the	DET
hjic-106	118	7	first	first	ADJ
hjic-106	118	8	quasi	quasi	ADJ
hjic-106	118	9	-	-	ADJ
hjic-106	118	10	continuous	continuous	ADJ
hjic-106	118	11	run	run	NOUN
hjic-106	118	12	,	,	PUNCT
hjic-106	118	13	two	two	NUM
hjic-106	118	14	possible	possible	ADJ
hjic-106	118	15	ways	way	NOUN
hjic-106	118	16	were	be	AUX
hjic-106	118	17	tried	try	VERB
hjic-106	118	18	:	:	PUNCT
hjic-106	118	19	the	the	DET
hjic-106	118	20	first	first	ADJ
hjic-106	118	21	was	be	AUX
hjic-106	118	22	the	the	DET
hjic-106	118	23	reduction	reduction	NOUN
hjic-106	118	24	of	of	ADP
hjic-106	118	25	the	the	DET
hjic-106	118	26	switching	switching	NOUN
hjic-106	118	27	time	time	NOUN
hjic-106	118	28	,	,	PUNCT
hjic-106	118	29	but	but	CCONJ
hjic-106	118	30	in	in	ADP
hjic-106	118	31	this	this	DET
hjic-106	118	32	case	case	NOUN
hjic-106	118	33	the	the	DET
hjic-106	118	34	sample	sample	NOUN
hjic-106	118	35	load	load	NOUN
hjic-106	118	36	and	and	CCONJ
hjic-106	118	37	volumes	volume	NOUN
hjic-106	118	38	of	of	ADP
hjic-106	118	39	solvents	solvent	NOUN
hjic-106	118	40	in	in	ADP
hjic-106	118	41	each	each	DET
hjic-106	118	42	zone	zone	NOUN
hjic-106	118	43	were	be	AUX
hjic-106	118	44	also	also	ADV
hjic-106	118	45	decreased	decrease	VERB
hjic-106	118	46	,	,	PUNCT
hjic-106	118	47	therefore	therefore	ADV
hjic-106	118	48	finding	find	VERB
hjic-106	118	49	the	the	DET
hjic-106	118	50	optimal	optimal	ADJ
hjic-106	118	51	set	set	NOUN
hjic-106	118	52	of	of	ADP
hjic-106	118	53	process	process	NOUN
hjic-106	118	54	parameters	parameter	NOUN
hjic-106	118	55	was	be	AUX
hjic-106	118	56	difficult	difficult	ADJ
hjic-106	118	57	.	.	PUNCT
hjic-106	119	1	(	(	PUNCT
hjic-106	119	2	2	2	X
hjic-106	119	3	.	.	X
hjic-106	119	4	experiment	experiment	NOUN
hjic-106	119	5	in	in	ADP
hjic-106	119	6	table	table	NOUN
hjic-106	119	7	2	2	NUM
hjic-106	119	8	.	.	PUNCT
hjic-106	119	9	)	)	PUNCT
hjic-106	120	1	•	•	ADP
hjic-106	120	2	the	the	DET
hjic-106	120	3	other	other	ADJ
hjic-106	120	4	(	(	PUNCT
hjic-106	120	5	easier	easy	ADJ
hjic-106	120	6	)	)	PUNCT
hjic-106	120	7	way	way	NOUN
hjic-106	120	8	was	be	AUX
hjic-106	120	9	decreasing	decrease	VERB
hjic-106	120	10	the	the	DET
hjic-106	120	11	flow	flow	NOUN
hjic-106	120	12	rate	rate	NOUN
hjic-106	120	13	in	in	ADP
hjic-106	120	14	the	the	DET
hjic-106	120	15	zone	zone	NOUN
hjic-106	120	16	of	of	ADP
hjic-106	120	17	the	the	DET
hjic-106	120	18	less	less	ADV
hjic-106	120	19	retained	retain	VERB
hjic-106	120	20	impurities	impurity	NOUN
hjic-106	120	21	.	.	PUNCT
hjic-106	121	1	(	(	PUNCT
hjic-106	121	2	3	3	X
hjic-106	121	3	.	.	X
hjic-106	121	4	experiment	experiment	NOUN
hjic-106	121	5	)	)	PUNCT
hjic-106	121	6	fig	fig	NOUN
hjic-106	121	7	.	.	PUNCT
hjic-106	122	1	6	6	NUM
hjic-106	122	2	.	.	PUNCT
hjic-106	122	3	:	:	PUNCT
hjic-106	123	1	chromatograms	chromatogram	NOUN
hjic-106	123	2	of	of	ADP
hjic-106	123	3	the	the	DET
hjic-106	123	4	pure	pure	ADJ
hjic-106	123	5	main	main	ADJ
hjic-106	123	6	fractions	fraction	NOUN
hjic-106	123	7	eluted	elute	VERB
hjic-106	123	8	from	from	ADP
hjic-106	123	9	successive	successive	ADJ
hjic-106	123	10	columns	column	NOUN
hjic-106	123	11	19	19	NUM
hjic-106	123	12	in	in	ADP
hjic-106	123	13	the	the	DET
hjic-106	123	14	4	4	NUM
hjic-106	123	15	.	.	NUM
hjic-106	123	16	,	,	PUNCT
hjic-106	123	17	5	5	NUM
hjic-106	123	18	.	.	NUM
hjic-106	123	19	and	and	CCONJ
hjic-106	123	20	6	6	NUM
hjic-106	123	21	.	.	PUNCT
hjic-106	123	22	experiments	experiment	VERB
hjic-106	123	23	the	the	DET
hjic-106	123	24	cut	cut	NOUN
hjic-106	123	25	point	point	NOUN
hjic-106	123	26	at	at	ADP
hjic-106	123	27	the	the	DET
hjic-106	123	28	end	end	NOUN
hjic-106	123	29	tail	tail	NOUN
hjic-106	123	30	of	of	ADP
hjic-106	123	31	the	the	DET
hjic-106	123	32	main	main	ADJ
hjic-106	123	33	fraction	fraction	NOUN
hjic-106	123	34	was	be	AUX
hjic-106	123	35	optimized	optimize	VERB
hjic-106	123	36	with	with	ADP
hjic-106	123	37	varying	vary	VERB
hjic-106	123	38	the	the	DET
hjic-106	123	39	flow	flow	NOUN
hjic-106	123	40	rate	rate	NOUN
hjic-106	123	41	in	in	ADP
hjic-106	123	42	the	the	DET
hjic-106	123	43	zone	zone	NOUN
hjic-106	123	44	of	of	ADP
hjic-106	123	45	the	the	DET
hjic-106	123	46	active	active	ADJ
hjic-106	123	47	compound	compound	NOUN
hjic-106	123	48	for	for	ADP
hjic-106	123	49	the	the	DET
hjic-106	123	50	purpose	purpose	NOUN
hjic-106	123	51	of	of	ADP
hjic-106	123	52	keeping	keep	VERB
hjic-106	123	53	the	the	DET
hjic-106	123	54	recovery	recovery	NOUN
hjic-106	123	55	as	as	ADV
hjic-106	123	56	high	high	ADJ
hjic-106	123	57	as	as	ADP
hjic-106	123	58	possible	possible	ADJ
hjic-106	123	59	and	and	CCONJ
hjic-106	123	60	the	the	DET
hjic-106	123	61	level	level	NOUN
hjic-106	123	62	of	of	ADP
hjic-106	123	63	the	the	DET
hjic-106	123	64	above	above	ADV
hjic-106	123	65	-	-	PUNCT
hjic-106	123	66	mentioned	mention	VERB
hjic-106	123	67	impurity	impurity	NOUN
hjic-106	123	68	under	under	ADP
hjic-106	123	69	a	a	DET
hjic-106	123	70	certain	certain	ADJ
hjic-106	123	71	limit	limit	NOUN
hjic-106	123	72	,	,	PUNCT
hjic-106	123	73	with	with	ADP
hjic-106	123	74	respect	respect	NOUN
hjic-106	123	75	to	to	ADP
hjic-106	123	76	the	the	DET
hjic-106	123	77	cleaning	clean	VERB
hjic-106	123	78	effect	effect	NOUN
hjic-106	123	79	of	of	ADP
hjic-106	123	80	the	the	DET
hjic-106	123	81	crystallisation	crystallisation	NOUN
hjic-106	123	82	step	step	NOUN
hjic-106	123	83	.	.	PUNCT
hjic-106	124	1	with	with	ADP
hjic-106	124	2	the	the	DET
hjic-106	124	3	best	good	ADJ
hjic-106	124	4	process	process	NOUN
hjic-106	124	5	parameters	parameter	NOUN
hjic-106	124	6	a	a	DET
hjic-106	124	7	repetition	repetition	NOUN
hjic-106	124	8	was	be	AUX
hjic-106	124	9	carried	carry	VERB
hjic-106	124	10	out	out	ADP
hjic-106	124	11	.	.	PUNCT
hjic-106	125	1	(	(	PUNCT
hjic-106	125	2	7	7	X
hjic-106	125	3	.	.	X
hjic-106	125	4	experiment	experiment	NOUN
hjic-106	125	5	)	)	PUNCT
hjic-106	125	6	in	in	ADP
hjic-106	125	7	the	the	DET
hjic-106	125	8	final	final	ADJ
hjic-106	125	9	step	step	NOUN
hjic-106	125	10	(	(	PUNCT
hjic-106	125	11	8	8	NUM
hjic-106	125	12	.	.	PUNCT
hjic-106	126	1	experiment	experiment	NOUN
hjic-106	126	2	)	)	PUNCT
hjic-106	126	3	the	the	DET
hjic-106	126	4	productivity	productivity	NOUN
hjic-106	126	5	was	be	AUX
hjic-106	126	6	increased	increase	VERB
hjic-106	126	7	with	with	ADP
hjic-106	126	8	decreasing	decrease	VERB
hjic-106	126	9	the	the	DET
hjic-106	126	10	switching	switching	NOUN
hjic-106	126	11	time	time	NOUN
hjic-106	126	12	and	and	CCONJ
hjic-106	126	13	proportionally	proportionally	ADV
hjic-106	126	14	increasing	increase	VERB
hjic-106	126	15	the	the	DET
hjic-106	126	16	flow	flow	NOUN
hjic-106	126	17	rates	rate	NOUN
hjic-106	126	18	at	at	ADP
hjic-106	126	19	the	the	DET
hjic-106	126	20	same	same	ADJ
hjic-106	126	21	time	time	NOUN
hjic-106	126	22	.	.	PUNCT
hjic-106	127	1	the	the	DET
hjic-106	127	2	last	last	ADJ
hjic-106	127	3	two	two	NUM
hjic-106	127	4	runs	run	NOUN
hjic-106	127	5	,	,	PUNCT
hjic-106	127	6	switching	switch	VERB
hjic-106	127	7	from	from	ADP
hjic-106	127	8	parameter	parameter	NOUN
hjic-106	127	9	set	set	NOUN
hjic-106	127	10	of	of	ADP
hjic-106	127	11	7	7	NUM
hjic-106	127	12	.	.	PUNCT
hjic-106	127	13	experiment	experiment	NOUN
hjic-106	127	14	to	to	ADP
hjic-106	127	15	the	the	DET
hjic-106	127	16	ones	one	NOUN
hjic-106	127	17	of	of	ADP
hjic-106	127	18	8	8	NUM
hjic-106	127	19	.	.	PUNCT
hjic-106	128	1	experiment	experiment	NOUN
hjic-106	128	2	,	,	PUNCT
hjic-106	128	3	with	with	ADP
hjic-106	128	4	two	two	NUM
hjic-106	128	5	transient	transient	ADJ
hjic-106	128	6	peaks	peak	NOUN
hjic-106	128	7	can	can	AUX
hjic-106	128	8	be	be	AUX
hjic-106	128	9	seen	see	VERB
hjic-106	128	10	in	in	ADP
hjic-106	128	11	fig	fig	NOUN
hjic-106	128	12	.	.	PUNCT
hjic-106	129	1	6	6	NUM
hjic-106	129	2	.	.	PUNCT
hjic-106	129	3	the	the	DET
hjic-106	129	4	reason	reason	NOUN
hjic-106	129	5	of	of	ADP
hjic-106	129	6	transients	transient	NOUN
hjic-106	129	7	is	be	AUX
hjic-106	129	8	that	that	SCONJ
hjic-106	129	9	,	,	PUNCT
hjic-106	129	10	when	when	SCONJ
hjic-106	129	11	the	the	DET
hjic-106	129	12	experimental	experimental	ADJ
hjic-106	129	13	parameters	parameter	NOUN
hjic-106	129	14	were	be	AUX
hjic-106	129	15	changed	change	VERB
hjic-106	129	16	,	,	PUNCT
hjic-106	129	17	the	the	DET
hjic-106	129	18	peak	peak	NOUN
hjic-106	129	19	of	of	ADP
hjic-106	129	20	the	the	DET
hjic-106	129	21	main	main	ADJ
hjic-106	129	22	fraction	fraction	NOUN
hjic-106	129	23	from	from	ADP
hjic-106	129	24	the	the	DET
hjic-106	129	25	actually	actually	ADV
hjic-106	129	26	injected	inject	VERB
hjic-106	129	27	sample	sample	NOUN
hjic-106	129	28	eluted	elute	VERB
hjic-106	129	29	after	after	ADP
hjic-106	129	30	two	two	NUM
hjic-106	129	31	switching	switching	NOUN
hjic-106	129	32	.	.	PUNCT
hjic-106	130	1	that	that	PRON
hjic-106	130	2	is	be	AUX
hjic-106	130	3	why	why	SCONJ
hjic-106	130	4	the	the	DET
hjic-106	130	5	new	new	ADJ
hjic-106	130	6	valuable	valuable	ADJ
hjic-106	130	7	status	status	NOUN
hjic-106	130	8	was	be	AUX
hjic-106	130	9	possible	possible	ADJ
hjic-106	130	10	to	to	PART
hjic-106	130	11	see	see	VERB
hjic-106	130	12	on	on	ADP
hjic-106	130	13	the	the	DET
hjic-106	130	14	recorder	recorder	NOUN
hjic-106	130	15	after	after	ADP
hjic-106	130	16	two	two	NUM
hjic-106	130	17	transient	transient	ADJ
hjic-106	130	18	peaks	peak	NOUN
hjic-106	130	19	.	.	PUNCT
hjic-106	131	1	the	the	DET
hjic-106	131	2	specific	specific	ADJ
hjic-106	131	3	capacity	capacity	NOUN
hjic-106	131	4	parameters	parameter	NOUN
hjic-106	131	5	of	of	ADP
hjic-106	131	6	7	7	NUM
hjic-106	131	7	.	.	PUNCT
hjic-106	131	8	and	and	CCONJ
hjic-106	131	9	8	8	NUM
hjic-106	131	10	.	.	NUM
hjic-106	131	11	runs	run	NOUN
hjic-106	131	12	,	,	PUNCT
hjic-106	131	13	in	in	ADP
hjic-106	131	14	comparison	comparison	NOUN
hjic-106	131	15	with	with	ADP
hjic-106	131	16	the	the	DET
hjic-106	131	17	pilot	pilot	NOUN
hjic-106	131	18	-	-	PUNCT
hjic-106	131	19	plant	plant	NOUN
hjic-106	131	20	batch	batch	NOUN
hjic-106	131	21	elution	elution	NOUN
hjic-106	131	22	separation	separation	NOUN
hjic-106	131	23	are	be	AUX
hjic-106	131	24	shown	show	VERB
hjic-106	131	25	in	in	ADP
hjic-106	131	26	table	table	NOUN
hjic-106	131	27	3	3	NUM
hjic-106	131	28	.	.	PUNCT
hjic-106	131	29	table	table	NOUN
hjic-106	131	30	3	3	NUM
hjic-106	131	31	:	:	PUNCT
hjic-106	131	32	the	the	DET
hjic-106	131	33	specific	specific	ADJ
hjic-106	131	34	capacity	capacity	NOUN
hjic-106	131	35	parameters	parameter	NOUN
hjic-106	131	36	of	of	ADP
hjic-106	131	37	7	7	NUM
hjic-106	131	38	.	.	PUNCT
hjic-106	131	39	and	and	CCONJ
hjic-106	131	40	8	8	NUM
hjic-106	131	41	.	.	NUM
hjic-106	131	42	runs	run	VERB
hjic-106	131	43	in	in	ADP
hjic-106	131	44	comparison	comparison	NOUN
hjic-106	131	45	with	with	ADP
hjic-106	131	46	the	the	DET
hjic-106	131	47	pilot	pilot	NOUN
hjic-106	131	48	-	-	PUNCT
hjic-106	131	49	plant	plant	NOUN
hjic-106	131	50	batch	batch	NOUN
hjic-106	131	51	elution	elution	NOUN
hjic-106	131	52	separation	separation	NOUN
hjic-106	131	53	specific	specific	ADJ
hjic-106	131	54	capacity	capacity	NOUN
hjic-106	131	55	parameters	parameter	NOUN
hjic-106	131	56	experiment	experiment	VERB
hjic-106	131	57	specific	specific	ADJ
hjic-106	131	58	solvent	solvent	ADJ
hjic-106	131	59	consumption	consumption	NOUN
hjic-106	131	60	methylene	methylene	NOUN
hjic-106	131	61	chloride	chloride	NOUN
hjic-106	131	62	(	(	PUNCT
hjic-106	131	63	ml	ml	PROPN
hjic-106	131	64	g-1	g-1	PROPN
hjic-106	131	65	)	)	PUNCT
hjic-106	131	66	specific	specific	ADJ
hjic-106	131	67	solvent	solvent	ADJ
hjic-106	131	68	consumption	consumption	NOUN
hjic-106	131	69	ethyl	ethyl	PROPN
hjic-106	131	70	acetate	acetate	NOUN
hjic-106	131	71	(	(	PUNCT
hjic-106	131	72	ml	ml	PROPN
hjic-106	131	73	g-1	g-1	PROPN
hjic-106	131	74	)	)	PUNCT
hjic-106	132	1	productivity	productivity	NOUN
hjic-106	133	1	[	[	X
hjic-106	133	2	g	g	X
hjic-106	133	3	(	(	PUNCT
hjic-106	133	4	kg	kg	NOUN
hjic-106	133	5	packing	pack	VERB
hjic-106	133	6	hour)-1	hour)-1	PROPN
hjic-106	133	7	]	]	PUNCT
hjic-106	133	8	recovery	recovery	NOUN
hjic-106	133	9	(	(	PUNCT
hjic-106	133	10	m	m	PROPN
hjic-106	133	11	m-1	m-1	NUM
hjic-106	133	12	%	%	NOUN
hjic-106	133	13	)	)	PUNCT
hjic-106	133	14	batch	batch	NOUN
hjic-106	133	15	elution	elution	NOUN
hjic-106	133	16	pilot	pilot	NOUN
hjic-106	133	17	-	-	PUNCT
hjic-106	133	18	scale	scale	NOUN
hjic-106	133	19	499.51	499.51	NUM
hjic-106	133	20	214.34	214.34	NUM
hjic-106	133	21	10.15	10.15	NUM
hjic-106	133	22	84.26	84.26	NUM
hjic-106	133	23	7	7	NUM
hjic-106	133	24	.	.	PUNCT
hjic-106	133	25	836.02	836.02	NUM
hjic-106	133	26	409.97	409.97	NUM
hjic-106	133	27	4.11	4.11	NUM
hjic-106	133	28	86.85	86.85	NUM
hjic-106	133	29	8	8	NUM
hjic-106	133	30	.	.	PUNCT
hjic-106	134	1	761.58	761.58	NUM
hjic-106	134	2	374.30	374.30	NUM
hjic-106	134	3	6.75	6.75	NUM
hjic-106	134	4	95.06	95.06	NUM
hjic-106	134	5	in	in	ADP
hjic-106	134	6	the	the	DET
hjic-106	134	7	8	8	NUM
hjic-106	134	8	.	.	PUNCT
hjic-106	134	9	experiment	experiment	NOUN
hjic-106	134	10	a	a	DET
hjic-106	134	11	higher	high	ADJ
hjic-106	134	12	recovery	recovery	NOUN
hjic-106	134	13	resulted	result	VERB
hjic-106	134	14	a	a	DET
hjic-106	134	15	little	little	ADJ
hjic-106	134	16	bit	bit	NOUN
hjic-106	134	17	higher	high	ADJ
hjic-106	134	18	level	level	NOUN
hjic-106	134	19	of	of	ADP
hjic-106	134	20	impurities	impurity	NOUN
hjic-106	134	21	in	in	ADP
hjic-106	134	22	the	the	DET
hjic-106	134	23	product	product	NOUN
hjic-106	134	24	,	,	PUNCT
hjic-106	134	25	but	but	CCONJ
hjic-106	134	26	the	the	DET
hjic-106	134	27	quality	quality	NOUN
hjic-106	134	28	still	still	ADV
hjic-106	134	29	met	meet	VERB
hjic-106	134	30	the	the	DET
hjic-106	134	31	requirements	requirement	NOUN
hjic-106	134	32	.	.	PUNCT
hjic-106	135	1	conclusion	conclusion	VERB
hjic-106	135	2	the	the	DET
hjic-106	135	3	quasi	quasi	ADJ
hjic-106	135	4	-	-	ADJ
hjic-106	135	5	continuous	continuous	ADJ
hjic-106	135	6	elution	elution	NOUN
hjic-106	135	7	chromatographic	chromatographic	ADJ
hjic-106	135	8	purification	purification	NOUN
hjic-106	135	9	of	of	ADP
hjic-106	135	10	a	a	DET
hjic-106	135	11	steroid	steroid	NOUN
hjic-106	135	12	active	active	ADJ
hjic-106	135	13	compound	compound	NOUN
hjic-106	135	14	was	be	AUX
hjic-106	135	15	possible	possible	ADJ
hjic-106	135	16	to	to	PART
hjic-106	135	17	carry	carry	VERB
hjic-106	135	18	out	out	ADP
hjic-106	135	19	successfully	successfully	ADV
hjic-106	135	20	with	with	ADP
hjic-106	135	21	the	the	DET
hjic-106	135	22	help	help	NOUN
hjic-106	135	23	of	of	ADP
hjic-106	135	24	the	the	DET
hjic-106	135	25	rotating	rotate	VERB
hjic-106	135	26	switching	switching	NOUN
hjic-106	135	27	valve	valve	NOUN
hjic-106	135	28	of	of	ADP
hjic-106	135	29	a	a	DET
hjic-106	135	30	laboratory	laboratory	NOUN
hjic-106	135	31	-	-	PUNCT
hjic-106	135	32	scale	scale	NOUN
hjic-106	135	33	simulated	simulated	ADJ
hjic-106	135	34	moving	move	VERB
hjic-106	135	35	bed	bed	NOUN
hjic-106	135	36	(	(	PUNCT
hjic-106	135	37	smb	smb	NOUN
hjic-106	135	38	)	)	PUNCT
hjic-106	135	39	instrument	instrument	NOUN
hjic-106	135	40	.	.	PUNCT
hjic-106	136	1	the	the	DET
hjic-106	136	2	quality	quality	NOUN
hjic-106	136	3	of	of	ADP
hjic-106	136	4	the	the	DET
hjic-106	136	5	product	product	NOUN
hjic-106	136	6	,	,	PUNCT
hjic-106	136	7	gained	gain	VERB
hjic-106	136	8	at	at	ADP
hjic-106	136	9	optimum	optimum	ADJ
hjic-106	136	10	operating	operating	NOUN
hjic-106	136	11	conditions	condition	NOUN
hjic-106	136	12	met	meet	VERB
hjic-106	136	13	the	the	DET
hjic-106	136	14	purity	purity	NOUN
hjic-106	136	15	requirements	requirement	NOUN
hjic-106	136	16	(	(	PUNCT
hjic-106	136	17	purity	purity	NOUN
hjic-106	136	18	>	>	X
hjic-106	136	19	99	99	NUM
hjic-106	136	20	%	%	NOUN
hjic-106	136	21	,	,	PUNCT
hjic-106	136	22	maximum	maximum	ADJ
hjic-106	136	23	level	level	NOUN
hjic-106	136	24	of	of	ADP
hjic-106	136	25	individual	individual	ADJ
hjic-106	136	26	impurities	impurity	NOUN
hjic-106	136	27	<	<	X
hjic-106	136	28	0.3	0.3	NUM
hjic-106	136	29	%	%	NOUN
hjic-106	136	30	)	)	PUNCT
hjic-106	136	31	.	.	PUNCT
hjic-106	137	1	the	the	DET
hjic-106	137	2	main	main	ADJ
hjic-106	137	3	advantage	advantage	NOUN
hjic-106	137	4	of	of	ADP
hjic-106	137	5	applying	apply	VERB
hjic-106	137	6	this	this	DET
hjic-106	137	7	quasicontinuous	quasicontinuous	ADJ
hjic-106	137	8	separation	separation	NOUN
hjic-106	137	9	method	method	NOUN
hjic-106	137	10	is	be	AUX
hjic-106	137	11	that	that	SCONJ
hjic-106	137	12	the	the	DET
hjic-106	137	13	staff	staff	NOUN
hjic-106	137	14	need	need	VERB
hjic-106	137	15	for	for	ADP
hjic-106	137	16	processing	processing	NOUN
hjic-106	137	17	is	be	AUX
hjic-106	137	18	less	less	ADJ
hjic-106	137	19	,	,	PUNCT
hjic-106	137	20	than	than	ADP
hjic-106	137	21	in	in	ADP
hjic-106	137	22	case	case	NOUN
hjic-106	137	23	of	of	ADP
hjic-106	137	24	batch	batch	NOUN
hjic-106	137	25	elution	elution	NOUN
hjic-106	137	26	chromatographic	chromatographic	ADJ
hjic-106	137	27	separation	separation	NOUN
hjic-106	137	28	.	.	PUNCT
hjic-106	138	1	fraction	fraction	NOUN
hjic-106	138	2	collector	collector	NOUN
hjic-106	138	3	is	be	AUX
hjic-106	138	4	not	not	PART
hjic-106	138	5	needed	need	VERB
hjic-106	138	6	,	,	PUNCT
hjic-106	138	7	because	because	SCONJ
hjic-106	138	8	cutting	cut	VERB
hjic-106	138	9	is	be	AUX
hjic-106	138	10	done	do	VERB
hjic-106	138	11	automatically	automatically	ADV
hjic-106	138	12	by	by	ADP
hjic-106	138	13	switching	switch	VERB
hjic-106	138	14	the	the	DET
hjic-106	138	15	columns	column	NOUN
hjic-106	138	16	and	and	CCONJ
hjic-106	138	17	the	the	DET
hjic-106	138	18	main	main	ADJ
hjic-106	138	19	fractions	fraction	NOUN
hjic-106	138	20	coming	come	VERB
hjic-106	138	21	from	from	ADP
hjic-106	138	22	successive	successive	ADJ
hjic-106	138	23	columns	column	NOUN
hjic-106	138	24	can	can	AUX
hjic-106	138	25	be	be	AUX
hjic-106	138	26	pooled	pool	VERB
hjic-106	138	27	in	in	ADP
hjic-106	138	28	one	one	NUM
hjic-106	138	29	vessel	vessel	NOUN
hjic-106	138	30	.	.	PUNCT
hjic-106	139	1	comparing	compare	VERB
hjic-106	139	2	the	the	DET
hjic-106	139	3	specific	specific	ADJ
hjic-106	139	4	capacity	capacity	NOUN
hjic-106	139	5	parameters	parameter	NOUN
hjic-106	139	6	of	of	ADP
hjic-106	139	7	the	the	DET
hjic-106	139	8	quasi	quasi	ADJ
hjic-106	139	9	-	-	ADJ
hjic-106	139	10	continuous	continuous	ADJ
hjic-106	139	11	process	process	NOUN
hjic-106	139	12	with	with	ADP
hjic-106	139	13	the	the	DET
hjic-106	139	14	batch	batch	NOUN
hjic-106	139	15	pilot	pilot	NOUN
hjic-106	139	16	-	-	PUNCT
hjic-106	139	17	scale	scale	NOUN
hjic-106	139	18	separation	separation	NOUN
hjic-106	139	19	,	,	PUNCT
hjic-106	139	20	the	the	DET
hjic-106	139	21	specific	specific	ADJ
hjic-106	139	22	solvent	solvent	ADJ
hjic-106	139	23	consumption	consumption	NOUN
hjic-106	139	24	is	be	AUX
hjic-106	139	25	higher	high	ADJ
hjic-106	139	26	and	and	CCONJ
hjic-106	139	27	the	the	DET
hjic-106	139	28	productivity	productivity	NOUN
hjic-106	139	29	is	be	AUX
hjic-106	139	30	lower	low	ADJ
hjic-106	139	31	.	.	PUNCT
hjic-106	140	1	but	but	CCONJ
hjic-106	140	2	mention	mention	VERB
hjic-106	140	3	must	must	AUX
hjic-106	140	4	be	be	AUX
hjic-106	140	5	made	make	VERB
hjic-106	140	6	,	,	PUNCT
hjic-106	140	7	that	that	SCONJ
hjic-106	140	8	the	the	DET
hjic-106	140	9	number	number	NOUN
hjic-106	140	10	of	of	ADP
hjic-106	140	11	columns	column	NOUN
hjic-106	140	12	applied	apply	VERB
hjic-106	140	13	in	in	ADP
hjic-106	140	14	the	the	DET
hjic-106	140	15	smb	smb	PROPN
hjic-106	140	16	instrument	instrument	NOUN
hjic-106	140	17	were	be	AUX
hjic-106	140	18	eight	eight	NUM
hjic-106	140	19	instead	instead	ADV
hjic-106	140	20	of	of	ADP
hjic-106	140	21	the	the	DET
hjic-106	140	22	necessary	necessary	ADJ
hjic-106	140	23	five	five	NUM
hjic-106	140	24	because	because	SCONJ
hjic-106	140	25	of	of	ADP
hjic-106	140	26	the	the	DET
hjic-106	140	27	construction	construction	NOUN
hjic-106	140	28	of	of	ADP
hjic-106	140	29	the	the	DET
hjic-106	140	30	smb	smb	PROPN
hjic-106	140	31	unit	unit	NOUN
hjic-106	140	32	.	.	PUNCT
hjic-106	141	1	the	the	DET
hjic-106	141	2	columns	column	NOUN
hjic-106	141	3	applied	apply	VERB
hjic-106	141	4	in	in	ADP
hjic-106	141	5	the	the	DET
hjic-106	141	6	smb	smb	PROPN
hjic-106	141	7	instrument	instrument	NOUN
hjic-106	141	8	were	be	AUX
hjic-106	141	9	shorter	short	ADJ
hjic-106	141	10	than	than	ADP
hjic-106	141	11	the	the	DET
hjic-106	141	12	pilot	pilot	NOUN
hjic-106	141	13	-	-	PUNCT
hjic-106	141	14	scale	scale	NOUN
hjic-106	141	15	column	column	NOUN
hjic-106	141	16	,	,	PUNCT
hjic-106	141	17	so	so	CCONJ
hjic-106	141	18	the	the	DET
hjic-106	141	19	theoretical	theoretical	ADJ
hjic-106	141	20	plate	plate	NOUN
hjic-106	141	21	number	number	NOUN
hjic-106	141	22	of	of	ADP
hjic-106	141	23	these	these	DET
hjic-106	141	24	columns	column	NOUN
hjic-106	141	25	was	be	AUX
hjic-106	141	26	considerably	considerably	ADV
hjic-106	141	27	lower	low	ADJ
hjic-106	141	28	,	,	PUNCT
hjic-106	141	29	therefore	therefore	ADV
hjic-106	141	30	the	the	DET
hjic-106	141	31	specific	specific	ADJ
hjic-106	141	32	sample	sample	NOUN
hjic-106	141	33	load	load	NOUN
hjic-106	141	34	also	also	ADV
hjic-106	141	35	had	have	VERB
hjic-106	141	36	to	to	PART
hjic-106	141	37	be	be	AUX
hjic-106	141	38	lower	low	ADJ
hjic-106	141	39	.	.	PUNCT
hjic-106	142	1	(	(	PUNCT
hjic-106	142	2	in	in	ADP
hjic-106	142	3	case	case	NOUN
hjic-106	142	4	of	of	ADP
hjic-106	142	5	pilot	pilot	NOUN
hjic-106	142	6	-	-	PUNCT
hjic-106	142	7	scale	scale	NOUN
hjic-106	142	8	column	column	NOUN
hjic-106	142	9	the	the	DET
hjic-106	142	10	specific	specific	ADJ
hjic-106	142	11	sample	sample	NOUN
hjic-106	142	12	load	load	NOUN
hjic-106	142	13	was	be	AUX
hjic-106	142	14	0.02	0.02	NUM
hjic-106	142	15	[	[	X
hjic-106	142	16	g	g	NOUN
hjic-106	142	17	sample	sample	NOUN
hjic-106	142	18	g-1	g-1	ADJ
hjic-106	142	19	packing	packing	NOUN
hjic-106	142	20	material	material	NOUN
hjic-106	142	21	]	]	PUNCT
hjic-106	142	22	,	,	PUNCT
hjic-106	142	23	while	while	SCONJ
hjic-106	142	24	in	in	ADP
hjic-106	142	25	quasi	quasi	ADJ
hjic-106	142	26	-	-	ADJ
hjic-106	142	27	continuous	continuous	ADJ
hjic-106	142	28	process	process	NOUN
hjic-106	142	29	it	it	PRON
hjic-106	142	30	was	be	AUX
hjic-106	142	31	only	only	ADV
hjic-106	142	32	0.0143	0.0143	NUM
hjic-106	143	1	[	[	X
hjic-106	143	2	g	g	NOUN
hjic-106	143	3	sample	sample	NOUN
hjic-106	143	4	g-1	g-1	ADJ
hjic-106	143	5	packing	packing	NOUN
hjic-106	143	6	material	material	NOUN
hjic-106	143	7	]	]	PUNCT
hjic-106	143	8	.	.	PUNCT
hjic-106	143	9	)	)	PUNCT
hjic-106	144	1	the	the	DET
hjic-106	144	2	robustness	robustness	NOUN
hjic-106	144	3	of	of	ADP
hjic-106	144	4	the	the	DET
hjic-106	144	5	process	process	NOUN
hjic-106	144	6	demands	demand	VERB
hjic-106	144	7	the	the	DET
hjic-106	144	8	uniformity	uniformity	NOUN
hjic-106	144	9	of	of	ADP
hjic-106	144	10	columns	column	NOUN
hjic-106	144	11	inserted	insert	VERB
hjic-106	144	12	in	in	ADP
hjic-106	144	13	the	the	DET
hjic-106	144	14	smb	smb	PROPN
hjic-106	144	15	instrument	instrument	NOUN
hjic-106	144	16	.	.	PUNCT
hjic-106	145	1	the	the	DET
hjic-106	145	2	change	change	NOUN
hjic-106	145	3	of	of	ADP
hjic-106	145	4	temperature	temperature	NOUN
hjic-106	145	5	has	have	VERB
hjic-106	145	6	strong	strong	ADJ
hjic-106	145	7	impact	impact	NOUN
hjic-106	145	8	on	on	ADP
hjic-106	145	9	the	the	DET
hjic-106	145	10	adsorption	adsorption	NOUN
hjic-106	145	11	behaviour	behaviour	NOUN
hjic-106	145	12	of	of	ADP
hjic-106	145	13	compounds	compound	NOUN
hjic-106	145	14	,	,	PUNCT
hjic-106	145	15	therefore	therefore	ADV
hjic-106	145	16	transients	transient	NOUN
hjic-106	145	17	in	in	ADP
hjic-106	145	18	temperature	temperature	NOUN
hjic-106	145	19	can	can	AUX
hjic-106	145	20	detrimentally	detrimentally	ADV
hjic-106	145	21	influence	influence	VERB
hjic-106	145	22	the	the	DET
hjic-106	145	23	separation	separation	NOUN
hjic-106	145	24	.	.	PUNCT
hjic-106	146	1	symbols	symbols	PROPN
hjic-106	146	2	i.d	i.d	PROPN
hjic-106	146	3	.	.	PROPN
hjic-106	146	4	internal	internal	PROPN
hjic-106	146	5	diameter	diameter	NOUN
hjic-106	146	6	f	f	PROPN
hjic-106	146	7	feed	feed	NOUN
hjic-106	146	8	c	c	NOUN
hjic-106	146	9	concentration	concentration	NOUN
hjic-106	146	10	of	of	ADP
hjic-106	146	11	the	the	DET
hjic-106	146	12	compounds	compound	NOUN
hjic-106	146	13	r	r	NOUN
hjic-106	146	14	raffinate	raffinate	NOUN
hjic-106	146	15	e	e	NOUN
hjic-106	146	16	extract	extract	VERB
hjic-106	146	17	l	l	NOUN
hjic-106	146	18	liquid	liquid	ADJ
hjic-106	146	19	recycle	recycle	NOUN
hjic-106	146	20	d	d	X
hjic-106	146	21	fresh	fresh	ADJ
hjic-106	146	22	solvent	solvent	NOUN
hjic-106	146	23	p	p	NOUN
hjic-106	146	24	“	"	PUNCT
hjic-106	146	25	recycle	recycle	NOUN
hjic-106	146	26	of	of	ADP
hjic-106	146	27	the	the	DET
hjic-106	146	28	packing	packing	NOUN
hjic-106	146	29	”	"	PUNCT
hjic-106	146	30	,	,	PUNCT
hjic-106	146	31	column	column	NOUN
hjic-106	146	32	switching	switch	VERB
hjic-106	146	33	time	time	NOUN
hjic-106	146	34	indices	index	NOUN
hjic-106	146	35	w	w	ADP
hjic-106	146	36	less	less	ADV
hjic-106	146	37	retained	retain	VERB
hjic-106	146	38	compound	compound	NOUN
hjic-106	146	39	s	s	PART
hjic-106	146	40	more	more	ADV
hjic-106	146	41	retained	retain	VERB
hjic-106	146	42	compound	compound	NOUN
hjic-106	146	43	f	f	NOUN
hjic-106	146	44	feed	feed	NOUN
hjic-106	146	45	r	r	NOUN
hjic-106	146	46	raffinate	raffinate	NOUN
hjic-106	146	47	e	e	NOUN
hjic-106	146	48	extract	extract	VERB
hjic-106	146	49	20	20	NUM
hjic-106	146	50	references	reference	NOUN
hjic-106	146	51	1	1	NUM
hjic-106	146	52	.	.	PUNCT
hjic-106	147	1	mann	mann	PROPN
hjic-106	147	2	g.	g.	PROPN
hjic-106	147	3	(	(	PUNCT
hjic-106	147	4	1998	1998	NUM
hjic-106	147	5	)	)	PUNCT
hjic-106	147	6	analusis	analusis	NOUN
hjic-106	147	7	26	26	NUM
hjic-106	147	8	(	(	PUNCT
hjic-106	147	9	7	7	NUM
hjic-106	147	10	):	):	PUNCT
hjic-106	147	11	76	76	NUM
hjic-106	147	12	-	-	SYM
hjic-106	147	13	82	82	NUM
hjic-106	147	14	2	2	NUM
hjic-106	147	15	.	.	PUNCT
hjic-106	148	1	colin	colin	PROPN
hjic-106	148	2	h.	h.	PROPN
hjic-106	148	3	(	(	PUNCT
hjic-106	148	4	1998	1998	NUM
hjic-106	148	5	)	)	PUNCT
hjic-106	148	6	analusis	analusis	NOUN
hjic-106	148	7	26	26	NUM
hjic-106	148	8	(	(	PUNCT
hjic-106	148	9	7	7	NUM
hjic-106	148	10	):	):	PUNCT
hjic-106	148	11	15	15	NUM
hjic-106	148	12	-	-	SYM
hjic-106	148	13	17	17	NUM
hjic-106	148	14	3	3	NUM
hjic-106	148	15	.	.	PUNCT
hjic-106	149	1	katti	katti	PROPN
hjic-106	149	2	a.	a.	NOUN
hjic-106	149	3	m.	m.	NOUN
hjic-106	149	4	,	,	PUNCT
hjic-106	149	5	jagland	jagland	NOUN
hjic-106	149	6	p.	p.	PROPN
hjic-106	149	7	(	(	PUNCT
hjic-106	149	8	1998	1998	NUM
hjic-106	149	9	)	)	PUNCT
hjic-106	149	10	analusis	analusis	NOUN
hjic-106	149	11	26	26	NUM
hjic-106	149	12	(	(	PUNCT
hjic-106	149	13	7	7	NUM
hjic-106	149	14	):	):	PUNCT
hjic-106	149	15	38	38	NUM
hjic-106	149	16	-	-	SYM
hjic-106	149	17	46	46	NUM
hjic-106	149	18	4	4	NUM
hjic-106	149	19	.	.	PUNCT
hjic-106	149	20	a.	a.	PROPN
hjic-106	149	21	seidel	seidel	PROPN
hjic-106	149	22	-	-	PUNCT
hjic-106	149	23	morgenstern	morgenstern	PROPN
hjic-106	149	24	(	(	PUNCT
hjic-106	149	25	1998	1998	NUM
hjic-106	149	26	)	)	PUNCT
hjic-106	149	27	analusis	analusis	NOUN
hjic-106	149	28	26	26	NUM
hjic-106	149	29	(	(	PUNCT
hjic-106	149	30	7	7	NUM
hjic-106	149	31	):	):	PUNCT
hjic-106	149	32	46	46	NUM
hjic-106	149	33	-	-	SYM
hjic-106	149	34	55	55	NUM
hjic-106	149	35	5	5	NUM
hjic-106	149	36	.	.	PUNCT
hjic-106	149	37	grill	grill	PROPN
hjic-106	149	38	c.	c.	PROPN
hjic-106	149	39	m.	m.	PROPN
hjic-106	149	40	,	,	PUNCT
hjic-106	149	41	miller	miller	PROPN
hjic-106	149	42	l.	l.	PROPN
hjic-106	149	43	,	,	PUNCT
hjic-106	149	44	yan	yan	PROPN
hjic-106	149	45	t.	t.	PROPN
hjic-106	149	46	q.	q.	PROPN
hjic-106	149	47	(	(	PUNCT
hjic-106	149	48	2004	2004	NUM
hjic-106	149	49	)	)	PUNCT
hjic-106	150	1	j	j	PROPN
hjic-106	150	2	chromatography	chromatography	NOUN
hjic-106	150	3	a	a	DET
hjic-106	150	4	1026	1026	NUM
hjic-106	150	5	:	:	PUNCT
hjic-106	150	6	101	101	NUM
hjic-106	150	7	-	-	SYM
hjic-106	150	8	108	108	NUM
hjic-106	150	9	6	6	NUM
hjic-106	150	10	.	.	PUNCT
hjic-106	150	11	nicoud	nicoud	PROPN
hjic-106	150	12	r.-m	r.-m	NOUN
hjic-106	150	13	.	.	PUNCT
hjic-106	151	1	(	(	PUNCT
hjic-106	151	2	1999	1999	NUM
hjic-106	151	3	)	)	PUNCT
hjic-106	151	4	pharmaceutical	pharmaceutical	NOUN
hjic-106	151	5	technology	technology	NOUN
hjic-106	151	6	europe	europe	PROPN
hjic-106	151	7	11	11	NUM
hjic-106	151	8	:	:	PUNCT
hjic-106	151	9	36	36	NUM
hjic-106	151	10	-	-	SYM
hjic-106	151	11	44	44	NUM
hjic-106	151	12	7	7	NUM
hjic-106	151	13	.	.	PUNCT
hjic-106	151	14	charton	charton	PROPN
hjic-106	151	15	f.	f.	PROPN
hjic-106	151	16	,	,	PUNCT
hjic-106	151	17	nicoud	nicoud	PROPN
hjic-106	151	18	r.-m	r.-m	NOUN
hjic-106	151	19	.	.	PUNCT
hjic-106	152	1	(	(	PUNCT
hjic-106	152	2	1995	1995	NUM
hjic-106	152	3	)	)	PUNCT
hjic-106	152	4	j	j	PROPN
hjic-106	152	5	chromatography	chromatography	NOUN
hjic-106	152	6	a	a	DET
hjic-106	152	7	702	702	NUM
hjic-106	152	8	:	:	SYM
hjic-106	152	9	97	97	NUM
hjic-106	152	10	-	-	SYM
hjic-106	152	11	112	112	NUM
hjic-106	152	12	8	8	NUM
hjic-106	152	13	.	.	PUNCT
hjic-106	153	1	khattabi	khattabi	PROPN
hjic-106	153	2	s.	s.	PROPN
hjic-106	153	3	,	,	PUNCT
hjic-106	153	4	cherrak	cherrak	PROPN
hjic-106	153	5	d.	d.	PROPN
hjic-106	153	6	e.	e.	PROPN
hjic-106	153	7	,	,	PUNCT
hjic-106	153	8	mihlbachler	mihlbachler	PROPN
hjic-106	153	9	k.	k.	PROPN
hjic-106	153	10	,	,	PUNCT
hjic-106	153	11	guiochon	guiochon	PROPN
hjic-106	153	12	g.	g.	PROPN
hjic-106	153	13	(	(	PUNCT
hjic-106	153	14	2000	2000	NUM
hjic-106	153	15	)	)	PUNCT
hjic-106	153	16	j	j	PROPN
hjic-106	153	17	chromatography	chromatography	NOUN
hjic-106	153	18	a	a	DET
hjic-106	153	19	893	893	NUM
hjic-106	153	20	:	:	PUNCT
hjic-106	153	21	307	307	NUM
hjic-106	153	22	-	-	SYM
hjic-106	153	23	319	319	NUM
hjic-106	153	24	9	9	NUM
hjic-106	153	25	.	.	PUNCT
hjic-106	153	26	pedeferri	pedeferri	PROPN
hjic-106	153	27	m.	m.	NOUN
hjic-106	153	28	,	,	PUNCT
hjic-106	153	29	zenoni	zenoni	PROPN
hjic-106	153	30	g.	g.	PROPN
hjic-106	153	31	,	,	PUNCT
hjic-106	153	32	mazzotti	mazzotti	PROPN
hjic-106	153	33	m.	m.	NOUN
hjic-106	153	34	,	,	PUNCT
hjic-106	153	35	morbidelli	morbidelli	PROPN
hjic-106	153	36	m.	m.	NOUN
hjic-106	153	37	(	(	PUNCT
hjic-106	153	38	1999	1999	NUM
hjic-106	153	39	)	)	PUNCT
hjic-106	153	40	chem	chem	NOUN
hjic-106	153	41	eng	eng	PROPN
hjic-106	153	42	sci	sci	PROPN
hjic-106	153	43	54	54	NUM
hjic-106	153	44	:	:	SYM
hjic-106	153	45	37353748	37353748	NUM
hjic-106	153	46	10	10	NUM
hjic-106	153	47	.	.	PUNCT
hjic-106	154	1	lee	lee	PROPN
hjic-106	154	2	h.-j	h.-j	PROPN
hjic-106	154	3	.	.	PROPN
hjic-106	154	4	,	,	PUNCT
hjic-106	155	1	xie	xie	PROPN
hjic-106	155	2	y.	y.	PROPN
hjic-106	155	3	,	,	PUNCT
hjic-106	155	4	koo	koo	PROPN
hjic-106	155	5	y.-m	y.-m	PROPN
hjic-106	155	6	.	.	PROPN
hjic-106	155	7	,	,	PUNCT
hjic-106	155	8	wang	wang	PROPN
hjic-106	155	9	n.-h	n.-h	PROPN
hjic-106	155	10	.	.	PUNCT
hjic-106	156	1	l.	l.	PROPN
hjic-106	156	2	(	(	PUNCT
hjic-106	156	3	2004	2004	NUM
hjic-106	156	4	)	)	PUNCT
hjic-106	156	5	biotechnol	biotechnol	ADJ
hjic-106	156	6	prog	prog	NOUN
hjic-106	156	7	20	20	NUM
hjic-106	156	8	:	:	SYM
hjic-106	156	9	179	179	NUM
hjic-106	156	10	-	-	SYM
hjic-106	156	11	192	192	NUM
hjic-106	156	12	11	11	NUM
hjic-106	156	13	.	.	PUNCT
hjic-106	157	1	santos	santos	PROPN
hjic-106	157	2	m.	m.	PROPN
hjic-106	157	3	a.	a.	PROPN
hjic-106	157	4	g.	g.	PROPN
hjic-106	157	5	,	,	PUNCT
hjic-106	157	6	veredas	veredas	PROPN
hjic-106	157	7	v.	v.	PROPN
hjic-106	157	8	,	,	PUNCT
hjic-106	157	9	silva	silva	PROPN
hjic-106	157	10	jr	jr	PROPN
hjic-106	157	11	.	.	PROPN
hjic-106	157	12	i.	i.	PROPN
hjic-106	157	13	j.	j.	PROPN
hjic-106	157	14	,	,	PUNCT
hjic-106	157	15	correia	correia	PROPN
hjic-106	157	16	c.	c.	PROPN
hjic-106	157	17	r.	r.	PROPN
hjic-106	157	18	d.	d.	PROPN
hjic-106	157	19	,	,	PUNCT
hjic-106	157	20	furlan	furlan	PROPN
hjic-106	157	21	l.	l.	PROPN
hjic-106	157	22	t.	t.	PROPN
hjic-106	157	23	,	,	PUNCT
hjic-106	157	24	santana	santana	PROPN
hjic-106	157	25	c.	c.	PROPN
hjic-106	157	26	c.	c.	PROPN
hjic-106	157	27	(	(	PUNCT
hjic-106	157	28	2004	2004	NUM
hjic-106	157	29	)	)	PUNCT
hjic-106	157	30	brazilian	brazilian	ADJ
hjic-106	157	31	journal	journal	NOUN
hjic-106	157	32	of	of	ADP
hjic-106	157	33	chemical	chemical	PROPN
hjic-106	157	34	engineering	engineering	NOUN
hjic-106	157	35	21	21	NUM
hjic-106	157	36	(	(	PUNCT
hjic-106	157	37	1	1	NUM
hjic-106	157	38	):	):	PUNCT
hjic-106	157	39	127	127	NUM
hjic-106	157	40	-	-	SYM
hjic-106	157	41	136	136	NUM
hjic-106	157	42	12	12	NUM
hjic-106	157	43	.	.	PUNCT
hjic-106	158	1	temesvári	temesvári	PROPN
hjic-106	158	2	k.	k.	PROPN
hjic-106	158	3	,	,	PUNCT
hjic-106	158	4	aranyi	aranyi	PROPN
hjic-106	158	5	a.	a.	PROPN
hjic-106	158	6	,	,	PUNCT
hjic-106	158	7	csukás	csukás	PROPN
hjic-106	158	8	b.	b.	PROPN
hjic-106	158	9	,	,	PUNCT
hjic-106	158	10	balogh	balogh	PROPN
hjic-106	158	11	s.	s.	PROPN
hjic-106	158	12	(	(	PUNCT
hjic-106	158	13	2004	2004	NUM
hjic-106	158	14	)	)	PUNCT
hjic-106	158	15	chromatographia	chromatographia	PROPN
hjic-106	158	16	suppl	suppl	PROPN
hjic-106	158	17	.	.	PUNCT
hjic-106	159	1	60	60	NUM
hjic-106	159	2	:	:	PUNCT
hjic-106	159	3	189	189	NUM
hjic-106	159	4	-	-	SYM
hjic-106	159	5	199	199	NUM
hjic-106	159	6	13	13	NUM
hjic-106	159	7	.	.	PUNCT
hjic-106	160	1	nicoud	nicoud	PROPN
hjic-106	160	2	r.-m	r.-m	PROPN
hjic-106	160	3	.	.	PUNCT
hjic-106	160	4	,	,	PUNCT
hjic-106	160	5	bailly	bailly	PROPN
hjic-106	160	6	m.	m.	NOUN
hjic-106	160	7	(	(	PUNCT
hjic-106	160	8	1992	1992	NUM
hjic-106	160	9	)	)	PUNCT
hjic-106	160	10	proceedings	proceeding	NOUN
hjic-106	160	11	of	of	ADP
hjic-106	160	12	“	"	PUNCT
hjic-106	160	13	prep	prep	NOUN
hjic-106	160	14	92	92	NUM
hjic-106	160	15	”	"	PUNCT
hjic-106	160	16	,	,	PUNCT
hjic-106	160	17	nancy	nancy	PROPN
hjic-106	160	18	(	(	PUNCT
hjic-106	160	19	france	france	PROPN
hjic-106	160	20	)	)	PUNCT
hjic-106	160	21	,	,	PUNCT
hjic-106	160	22	6	6	NUM
hjic-106	160	23	-	-	SYM
hjic-106	160	24	8	8	NUM
hjic-106	160	25	april	april	PROPN
hjic-106	160	26	,	,	PUNCT
hjic-106	160	27	isbn	isbn	PROPN
hjic-106	160	28	2905267	2905267	NUM
hjic-106	160	29	-	-	SYM
hjic-106	160	30	18	18	NUM
hjic-106	160	31	-	-	SYM
hjic-106	160	32	6	6	NUM
hjic-106	160	33	:	:	SYM
hjic-106	160	34	205	205	NUM
hjic-106	160	35	-	-	SYM
hjic-106	160	36	220	220	NUM
hjic-106	160	37	14	14	NUM
hjic-106	160	38	.	.	PUNCT
hjic-106	161	1	blehaut	blehaut	PROPN
hjic-106	161	2	j.	j.	PROPN
hjic-106	161	3	,	,	PUNCT
hjic-106	161	4	nicoud	nicoud	PROPN
hjic-106	161	5	r.-m	r.-m	NOUN
hjic-106	161	6	.	.	PUNCT
hjic-106	162	1	(	(	PUNCT
hjic-106	162	2	1998	1998	NUM
hjic-106	162	3	)	)	PUNCT
hjic-106	162	4	analusis	analusis	NOUN
hjic-106	162	5	26	26	NUM
hjic-106	162	6	(	(	PUNCT
hjic-106	162	7	7	7	NUM
hjic-106	162	8	):	):	PUNCT
hjic-106	162	9	60	60	NUM
hjic-106	162	10	-	-	SYM
hjic-106	162	11	70	70	NUM
hjic-106	162	12	15	15	NUM
hjic-106	162	13	.	.	PUNCT
hjic-106	163	1	guiochon	guiochon	PROPN
hjic-106	163	2	g.	g.	PROPN
hjic-106	163	3	(	(	PUNCT
hjic-106	163	4	2002	2002	NUM
hjic-106	163	5	)	)	PUNCT
hjic-106	163	6	j	j	PROPN
hjic-106	163	7	chromatography	chromatography	NOUN
hjic-106	163	8	a	a	DET
hjic-106	163	9	965	965	NUM
hjic-106	163	10	:	:	PUNCT
hjic-106	163	11	129	129	NUM
hjic-106	163	12	-	-	SYM
hjic-106	163	13	161	161	NUM
hjic-106	163	14	16	16	NUM
hjic-106	163	15	.	.	PUNCT
hjic-106	164	1	himbert	himbert	PROPN
hjic-106	164	2	f.	f.	PROPN
hjic-106	164	3	,	,	PUNCT
hjic-106	164	4	pennanec	pennanec	PROPN
hjic-106	164	5	r.	r.	PROPN
hjic-106	164	6	,	,	PUNCT
hjic-106	164	7	guillaumet	guillaumet	NOUN
hjic-106	164	8	g.	g.	PROPN
hjic-106	164	9	,	,	PUNCT
hjic-106	164	10	lafosse	lafosse	NOUN
hjic-106	164	11	m.	m.	NOUN
hjic-106	164	12	(	(	PUNCT
hjic-106	164	13	2004	2004	NUM
hjic-106	164	14	)	)	PUNCT
hjic-106	164	15	chromatographia	chromatographia	NOUN
hjic-106	164	16	60	60	NUM
hjic-106	164	17	:	:	PUNCT
hjic-106	164	18	269	269	NUM
hjic-106	164	19	-	-	SYM
hjic-106	164	20	274	274	NUM
hjic-106	164	21	17	17	NUM
hjic-106	164	22	.	.	PUNCT
hjic-106	165	1	yang	yang	PROPN
hjic-106	165	2	x.	x.	PROPN
hjic-106	165	3	,	,	PUNCT
hjic-106	165	4	liu	liu	PROPN
hjic-106	165	5	k.	k.	PROPN
hjic-106	165	6	,	,	PUNCT
hjic-106	165	7	xie	xie	PROPN
hjic-106	165	8	m.	m.	PROPN
hjic-106	165	9	(	(	PUNCT
hjic-106	165	10	1998	1998	NUM
hjic-106	165	11	)	)	PUNCT
hjic-106	165	12	j	j	PROPN
hjic-106	165	13	chromatography	chromatography	NOUN
hjic-106	165	14	a	a	DET
hjic-106	165	15	813	813	NUM
hjic-106	165	16	:	:	PUNCT
hjic-106	165	17	201	201	NUM
hjic-106	165	18	-	-	SYM
hjic-106	165	19	204	204	NUM
hjic-106	165	20	18	18	NUM
hjic-106	165	21	.	.	PUNCT
hjic-106	166	1	zhang	zhang	PROPN
hjic-106	166	2	x.	x.	PROPN
hjic-106	166	3	,	,	PUNCT
hjic-106	166	4	geoffroy	geoffroy	PROPN
hjic-106	166	5	p.	p.	PROPN
hjic-106	166	6	,	,	PUNCT
hjic-106	166	7	miesch	miesch	PROPN
hjic-106	166	8	m.	m.	PROPN
hjic-106	166	9	,	,	PUNCT
hjic-106	166	10	julien	julien	PROPN
hjic-106	166	11	-	-	PUNCT
hjic-106	166	12	david	david	PROPN
hjic-106	166	13	d.	d.	PROPN
hjic-106	166	14	,	,	PUNCT
hjic-106	166	15	raul	raul	PROPN
hjic-106	166	16	f.	f.	PROPN
hjic-106	166	17	,	,	PUNCT
hjic-106	166	18	aoudé	aoudé	PROPN
hjic-106	166	19	-	-	PUNCT
hjic-106	166	20	werner	werner	PROPN
hjic-106	166	21	d.	d.	PROPN
hjic-106	166	22	,	,	PUNCT
hjic-106	166	23	marchioni	marchioni	PROPN
hjic-106	166	24	e.	e.	PROPN
hjic-106	166	25	(	(	PUNCT
hjic-106	166	26	2005	2005	NUM
hjic-106	166	27	)	)	PUNCT
hjic-106	166	28	steroids	steroid	NOUN
hjic-106	166	29	‘	'	PUNCT
hjic-106	166	30	in	in	ADP
hjic-106	166	31	press	press	NOUN
hjic-106	166	32	’	'	PUNCT
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