id	sid	tid	token	lemma	pos
hjic-1157	1	1	hungarian	hungarian	ADJ
hjic-1157	1	2	journal	journal	NOUN
hjic-1157	1	3	of	of	ADP
hjic-1157	1	4	industry	industry	NOUN
hjic-1157	1	5	and	and	CCONJ
hjic-1157	1	6	chemistry	chemistry	NOUN
hjic-1157	1	7	vol	vol	NOUN
hjic-1157	1	8	.	.	PUNCT
hjic-1157	2	1	50	50	NUM
hjic-1157	2	2	pp	pp	NOUN
hjic-1157	2	3	.	.	PUNCT
hjic-1157	3	1	23–28	23–28	NUM
hjic-1157	3	2	(	(	PUNCT
hjic-1157	3	3	2022	2022	NUM
hjic-1157	3	4	)	)	PUNCT
hjic-1157	3	5	hjic.mk.uni-pannon.hu	hjic.mk.uni-pannon.hu	NOUN
hjic-1157	3	6	doi	doi	NOUN
hjic-1157	3	7	:	:	PUNCT
hjic-1157	3	8	10.33927	10.33927	NUM
hjic-1157	3	9	/	/	SYM
hjic-1157	3	10	hjic-2022	hjic-2022	NOUN
hjic-1157	3	11	-	-	PUNCT
hjic-1157	3	12	05	05	NUM
hjic-1157	3	13	production	production	NOUN
hjic-1157	3	14	of	of	ADP
hjic-1157	3	15	chiral	chiral	ADJ
hjic-1157	3	16	(	(	PUNCT
hjic-1157	3	17	s)-2	s)-2	NOUN
hjic-1157	3	18	-	-	PUNCT
hjic-1157	3	19	phenyl-1	phenyl-1	NOUN
hjic-1157	3	20	-	-	PUNCT
hjic-1157	3	21	propanol	propanol	NOUN
hjic-1157	3	22	by	by	ADP
hjic-1157	3	23	enantioselective	enantioselective	ADJ
hjic-1157	3	24	biocatalysts	biocatalyst	NOUN
hjic-1157	3	25	piroska	piroska	VERB
hjic-1157	3	26	lajtai	lajtai	NOUN
hjic-1157	3	27	-	-	PUNCT
hjic-1157	3	28	szabó	szabó	NOUN
hjic-1157	3	29	*	*	NOUN
hjic-1157	3	30	1	1	NUM
hjic-1157	3	31	,	,	PUNCT
hjic-1157	3	32	tímea	tímea	PROPN
hjic-1157	3	33	brigitta	brigitta	PROPN
hjic-1157	3	34	bagó1	bagó1	PROPN
hjic-1157	3	35	,	,	PUNCT
hjic-1157	3	36	and	and	CCONJ
hjic-1157	3	37	nándor	nándor	NOUN
hjic-1157	3	38	nemestóthy1	nemestóthy1	NOUN
hjic-1157	3	39	1research	1research	NUM
hjic-1157	3	40	group	group	NOUN
hjic-1157	3	41	on	on	ADP
hjic-1157	3	42	bioengineering	bioengineering	NOUN
hjic-1157	3	43	,	,	PUNCT
hjic-1157	3	44	membrane	membrane	NOUN
hjic-1157	3	45	technology	technology	NOUN
hjic-1157	3	46	and	and	CCONJ
hjic-1157	3	47	energetics	energetic	NOUN
hjic-1157	3	48	,	,	PUNCT
hjic-1157	3	49	university	university	NOUN
hjic-1157	3	50	of	of	ADP
hjic-1157	3	51	pannonia	pannonia	PROPN
hjic-1157	3	52	,	,	PUNCT
hjic-1157	3	53	egyetem	egyetem	NOUN
hjic-1157	3	54	u.	u.	PROPN
hjic-1157	3	55	10	10	NUM
hjic-1157	3	56	,	,	PUNCT
hjic-1157	3	57	veszprém	veszprém	NOUN
hjic-1157	3	58	,	,	PUNCT
hjic-1157	3	59	8200	8200	NUM
hjic-1157	3	60	,	,	PUNCT
hjic-1157	3	61	hungary	hungary	NOUN
hjic-1157	3	62	enantioselective	enantioselective	ADJ
hjic-1157	3	63	production	production	NOUN
hjic-1157	3	64	of	of	ADP
hjic-1157	3	65	(	(	PUNCT
hjic-1157	3	66	s)-2	s)-2	NOUN
hjic-1157	3	67	-	-	PUNCT
hjic-1157	3	68	phenyl-1	phenyl-1	NOUN
hjic-1157	3	69	-	-	PUNCT
hjic-1157	3	70	propanol	propanol	NOUN
hjic-1157	3	71	is	be	AUX
hjic-1157	3	72	important	important	ADJ
hjic-1157	3	73	as	as	SCONJ
hjic-1157	3	74	in	in	ADP
hjic-1157	3	75	order	order	NOUN
hjic-1157	3	76	to	to	PART
hjic-1157	3	77	be	be	AUX
hjic-1157	3	78	applied	apply	VERB
hjic-1157	3	79	in	in	ADP
hjic-1157	3	80	industry	industry	NOUN
hjic-1157	3	81	,	,	PUNCT
hjic-1157	3	82	a	a	DET
hjic-1157	3	83	high	high	ADJ
hjic-1157	3	84	degree	degree	NOUN
hjic-1157	3	85	of	of	ADP
hjic-1157	3	86	optical	optical	ADJ
hjic-1157	3	87	purity	purity	NOUN
hjic-1157	3	88	is	be	AUX
hjic-1157	3	89	required	require	VERB
hjic-1157	3	90	.	.	PUNCT
hjic-1157	4	1	besides	besides	SCONJ
hjic-1157	4	2	organocatalysts	organocatalyst	NOUN
hjic-1157	4	3	and	and	CCONJ
hjic-1157	4	4	metal	metal	NOUN
hjic-1157	4	5	complexes	complex	NOUN
hjic-1157	4	6	,	,	PUNCT
hjic-1157	4	7	biocatalysts	biocatalyst	NOUN
hjic-1157	4	8	can	can	AUX
hjic-1157	4	9	be	be	AUX
hjic-1157	4	10	used	use	VERB
hjic-1157	4	11	for	for	ADP
hjic-1157	4	12	its	its	PRON
hjic-1157	4	13	synthesis	synthesis	NOUN
hjic-1157	4	14	in	in	ADP
hjic-1157	4	15	their	their	PRON
hjic-1157	4	16	isolated	isolated	ADJ
hjic-1157	4	17	form	form	NOUN
hjic-1157	4	18	or	or	CCONJ
hjic-1157	4	19	as	as	ADP
hjic-1157	4	20	whole	whole	ADJ
hjic-1157	4	21	-	-	PUNCT
hjic-1157	4	22	cell	cell	NOUN
hjic-1157	4	23	biocatalysts	biocatalyst	NOUN
hjic-1157	4	24	,	,	PUNCT
hjic-1157	4	25	both	both	PRON
hjic-1157	4	26	of	of	ADP
hjic-1157	4	27	which	which	PRON
hjic-1157	4	28	have	have	VERB
hjic-1157	4	29	various	various	ADJ
hjic-1157	4	30	advantages	advantage	NOUN
hjic-1157	4	31	and	and	CCONJ
hjic-1157	4	32	disadvantages	disadvantage	NOUN
hjic-1157	4	33	.	.	PUNCT
hjic-1157	5	1	in	in	ADP
hjic-1157	5	2	this	this	DET
hjic-1157	5	3	research	research	NOUN
hjic-1157	5	4	,	,	PUNCT
hjic-1157	5	5	saccharomyces	saccharomyce	NOUN
hjic-1157	5	6	cerevisiae	cerevisiae	NOUN
hjic-1157	5	7	,	,	PUNCT
hjic-1157	5	8	as	as	ADP
hjic-1157	5	9	a	a	DET
hjic-1157	5	10	whole	whole	ADJ
hjic-1157	5	11	-	-	PUNCT
hjic-1157	5	12	cell	cell	NOUN
hjic-1157	5	13	biocatalyst	biocatalyst	NOUN
hjic-1157	5	14	,	,	PUNCT
hjic-1157	5	15	and	and	CCONJ
hjic-1157	5	16	recombinant	recombinant	ADJ
hjic-1157	5	17	horse	horse	NOUN
hjic-1157	5	18	-	-	PUNCT
hjic-1157	5	19	liver	liver	NOUN
hjic-1157	5	20	alcohol	alcohol	NOUN
hjic-1157	5	21	dehydrogenase	dehydrogenase	NOUN
hjic-1157	5	22	(	(	PUNCT
hjic-1157	5	23	adh	adh	PROPN
hjic-1157	5	24	)	)	PUNCT
hjic-1157	5	25	,	,	PUNCT
hjic-1157	5	26	as	as	ADP
hjic-1157	5	27	an	an	DET
hjic-1157	5	28	isolated	isolated	ADJ
hjic-1157	5	29	enzyme	enzyme	NOUN
hjic-1157	5	30	,	,	PUNCT
hjic-1157	5	31	were	be	AUX
hjic-1157	5	32	investigated	investigate	VERB
hjic-1157	5	33	in	in	ADP
hjic-1157	5	34	terms	term	NOUN
hjic-1157	5	35	of	of	ADP
hjic-1157	5	36	their	their	PRON
hjic-1157	5	37	activity	activity	NOUN
hjic-1157	5	38	,	,	PUNCT
hjic-1157	5	39	kinetics	kinetic	NOUN
hjic-1157	5	40	and	and	CCONJ
hjic-1157	5	41	enantioselectivity	enantioselectivity	NOUN
hjic-1157	5	42	.	.	PUNCT
hjic-1157	6	1	in	in	ADP
hjic-1157	6	2	the	the	DET
hjic-1157	6	3	case	case	NOUN
hjic-1157	6	4	of	of	ADP
hjic-1157	6	5	yeast	yeast	NOUN
hjic-1157	6	6	,	,	PUNCT
hjic-1157	6	7	the	the	DET
hjic-1157	6	8	rate	rate	NOUN
hjic-1157	6	9	of	of	ADP
hjic-1157	6	10	cofactor	cofactor	NOUN
hjic-1157	6	11	regeneration	regeneration	NOUN
hjic-1157	6	12	was	be	AUX
hjic-1157	6	13	twice	twice	ADV
hjic-1157	6	14	that	that	PRON
hjic-1157	6	15	of	of	ADP
hjic-1157	6	16	substrate	substrate	NOUN
hjic-1157	6	17	conversion	conversion	NOUN
hjic-1157	6	18	,	,	PUNCT
hjic-1157	6	19	moreover	moreover	ADV
hjic-1157	6	20	,	,	PUNCT
hjic-1157	6	21	the	the	DET
hjic-1157	6	22	biocatalyst	biocatalyst	NOUN
hjic-1157	6	23	saccharomyces	saccharomyce	NOUN
hjic-1157	6	24	cerevisiae	cerevisiae	NOUN
hjic-1157	6	25	can	can	AUX
hjic-1157	6	26	be	be	AUX
hjic-1157	6	27	characterised	characterise	VERB
hjic-1157	6	28	by	by	ADP
hjic-1157	6	29	substrate	substrate	NOUN
hjic-1157	6	30	-	-	PUNCT
hjic-1157	6	31	limited	limit	VERB
hjic-1157	6	32	kinetics	kinetic	NOUN
hjic-1157	6	33	and	and	CCONJ
hjic-1157	6	34	low	low	ADJ
hjic-1157	6	35	enantioselectivity	enantioselectivity	NOUN
hjic-1157	6	36	.	.	PUNCT
hjic-1157	7	1	in	in	ADP
hjic-1157	7	2	contrast	contrast	NOUN
hjic-1157	7	3	,	,	PUNCT
hjic-1157	7	4	the	the	DET
hjic-1157	7	5	isolated	isolated	ADJ
hjic-1157	7	6	enzyme	enzyme	NOUN
hjic-1157	7	7	recombinant	recombinant	ADJ
hjic-1157	7	8	horse	horse	NOUN
hjic-1157	7	9	-	-	PUNCT
hjic-1157	7	10	liver	liver	NOUN
hjic-1157	7	11	adh	adh	NOUN
hjic-1157	7	12	exhibited	exhibit	VERB
hjic-1157	7	13	biphasic	biphasic	ADJ
hjic-1157	7	14	kinetics	kinetic	NOUN
hjic-1157	7	15	and	and	CCONJ
hjic-1157	7	16	cofactor	cofactor	NOUN
hjic-1157	7	17	regeneration	regeneration	NOUN
hjic-1157	7	18	was	be	AUX
hjic-1157	7	19	the	the	DET
hjic-1157	7	20	rate	rate	NOUN
hjic-1157	7	21	-	-	PUNCT
hjic-1157	7	22	limiting	limit	VERB
hjic-1157	7	23	step	step	NOUN
hjic-1157	7	24	.	.	PUNCT
hjic-1157	8	1	the	the	DET
hjic-1157	8	2	outstanding	outstanding	ADJ
hjic-1157	8	3	enantioselectivity	enantioselectivity	NOUN
hjic-1157	8	4	of	of	ADP
hjic-1157	8	5	recombinant	recombinant	ADJ
hjic-1157	8	6	horse	horse	NOUN
hjic-1157	8	7	-	-	PUNCT
hjic-1157	8	8	liver	liver	NOUN
hjic-1157	8	9	adh	adh	NOUN
hjic-1157	8	10	renders	render	VERB
hjic-1157	8	11	it	it	PRON
hjic-1157	8	12	a	a	DET
hjic-1157	8	13	promising	promising	ADJ
hjic-1157	8	14	catalyst	catalyst	NOUN
hjic-1157	8	15	for	for	ADP
hjic-1157	8	16	the	the	DET
hjic-1157	8	17	purpose	purpose	NOUN
hjic-1157	8	18	of	of	ADP
hjic-1157	8	19	this	this	DET
hjic-1157	8	20	synthesis	synthesis	NOUN
hjic-1157	8	21	.	.	PUNCT
hjic-1157	9	1	keywords	keyword	NOUN
hjic-1157	9	2	:	:	PUNCT
hjic-1157	9	3	alcohol	alcohol	NOUN
hjic-1157	9	4	dehydrogenase	dehydrogenase	NOUN
hjic-1157	9	5	,	,	PUNCT
hjic-1157	9	6	whole	whole	ADJ
hjic-1157	9	7	-	-	PUNCT
hjic-1157	9	8	cell	cell	NOUN
hjic-1157	9	9	biocatalyst	biocatalyst	NOUN
hjic-1157	9	10	,	,	PUNCT
hjic-1157	9	11	saccharomyces	saccharomyce	NOUN
hjic-1157	9	12	cerevisiae	cerevisiae	NOUN
hjic-1157	9	13	1	1	NUM
hjic-1157	9	14	.	.	PUNCT
hjic-1157	9	15	introduction	introduction	NOUN
hjic-1157	9	16	2	2	NUM
hjic-1157	9	17	-	-	PUNCT
hjic-1157	9	18	phenyl-1	phenyl-1	NOUN
hjic-1157	9	19	-	-	PUNCT
hjic-1157	9	20	propanol	propanol	NOUN
hjic-1157	9	21	is	be	AUX
hjic-1157	9	22	a	a	DET
hjic-1157	9	23	fragrance	fragrance	NOUN
hjic-1157	9	24	ingredient	ingredient	NOUN
hjic-1157	9	25	that	that	PRON
hjic-1157	9	26	produces	produce	VERB
hjic-1157	9	27	the	the	DET
hjic-1157	9	28	lila	lila	NOUN
hjic-1157	9	29	-	-	PUNCT
hjic-1157	9	30	hyacinth	hyacinth	NOUN
hjic-1157	9	31	odour	odour	NOUN
hjic-1157	9	32	commonly	commonly	ADV
hjic-1157	9	33	used	use	VERB
hjic-1157	9	34	in	in	ADP
hjic-1157	9	35	cosmetics	cosmetic	NOUN
hjic-1157	9	36	,	,	PUNCT
hjic-1157	9	37	fine	fine	ADJ
hjic-1157	9	38	fragrances	fragrance	NOUN
hjic-1157	9	39	and	and	CCONJ
hjic-1157	9	40	household	household	NOUN
hjic-1157	9	41	cleaners	cleaner	NOUN
hjic-1157	9	42	[	[	X
hjic-1157	9	43	1	1	NUM
hjic-1157	9	44	]	]	PUNCT
hjic-1157	9	45	.	.	PUNCT
hjic-1157	10	1	besides	besides	SCONJ
hjic-1157	10	2	,	,	PUNCT
hjic-1157	10	3	it	it	PRON
hjic-1157	10	4	is	be	AUX
hjic-1157	10	5	the	the	DET
hjic-1157	10	6	basis	basis	NOUN
hjic-1157	10	7	of	of	ADP
hjic-1157	10	8	some	some	DET
hjic-1157	10	9	non	non	ADJ
hjic-1157	10	10	-	-	ADJ
hjic-1157	10	11	steroidal	steroidal	ADJ
hjic-1157	10	12	anti	anti	ADJ
hjic-1157	10	13	-	-	ADJ
hjic-1157	10	14	inflammatory	inflammatory	ADJ
hjic-1157	10	15	drugs	drug	NOUN
hjic-1157	10	16	and	and	CCONJ
hjic-1157	10	17	the	the	DET
hjic-1157	10	18	precursor	precursor	NOUN
hjic-1157	10	19	of	of	ADP
hjic-1157	10	20	other	other	ADJ
hjic-1157	10	21	fragrances	fragrance	NOUN
hjic-1157	10	22	[	[	X
hjic-1157	10	23	2	2	NUM
hjic-1157	10	24	]	]	PUNCT
hjic-1157	10	25	.	.	PUNCT
hjic-1157	11	1	these	these	DET
hjic-1157	11	2	fields	field	NOUN
hjic-1157	11	3	of	of	ADP
hjic-1157	11	4	use	use	NOUN
hjic-1157	11	5	require	require	VERB
hjic-1157	11	6	a	a	DET
hjic-1157	11	7	high	high	ADJ
hjic-1157	11	8	degree	degree	NOUN
hjic-1157	11	9	of	of	ADP
hjic-1157	11	10	optical	optical	ADJ
hjic-1157	11	11	purity	purity	NOUN
hjic-1157	11	12	since	since	SCONJ
hjic-1157	11	13	the	the	DET
hjic-1157	11	14	enantiomers	enantiomer	NOUN
hjic-1157	11	15	of	of	ADP
hjic-1157	11	16	the	the	DET
hjic-1157	11	17	compound	compound	NOUN
hjic-1157	11	18	,	,	PUNCT
hjic-1157	11	19	by	by	ADP
hjic-1157	11	20	and	and	CCONJ
hjic-1157	11	21	large	large	ADJ
hjic-1157	11	22	,	,	PUNCT
hjic-1157	11	23	bring	bring	VERB
hjic-1157	11	24	about	about	ADP
hjic-1157	11	25	different	different	ADJ
hjic-1157	11	26	biological	biological	ADJ
hjic-1157	11	27	effects	effect	NOUN
hjic-1157	11	28	[	[	X
hjic-1157	11	29	3	3	NUM
hjic-1157	11	30	]	]	PUNCT
hjic-1157	11	31	.	.	PUNCT
hjic-1157	12	1	asymmetric	asymmetric	ADJ
hjic-1157	12	2	syntheses	synthesis	NOUN
hjic-1157	12	3	are	be	AUX
hjic-1157	12	4	preferentially	preferentially	ADV
hjic-1157	12	5	obtained	obtain	VERB
hjic-1157	12	6	using	use	VERB
hjic-1157	12	7	enzymes	enzyme	NOUN
hjic-1157	12	8	,	,	PUNCT
hjic-1157	12	9	given	give	VERB
hjic-1157	12	10	the	the	DET
hjic-1157	12	11	capability	capability	NOUN
hjic-1157	12	12	of	of	ADP
hjic-1157	12	13	most	most	ADJ
hjic-1157	12	14	to	to	PART
hjic-1157	12	15	catalyse	catalyse	VERB
hjic-1157	12	16	organic	organic	ADJ
hjic-1157	12	17	reactions	reaction	NOUN
hjic-1157	12	18	with	with	ADP
hjic-1157	12	19	high	high	ADJ
hjic-1157	12	20	enantioselectivity	enantioselectivity	NOUN
hjic-1157	12	21	under	under	ADP
hjic-1157	12	22	mild	mild	ADJ
hjic-1157	12	23	conditions	condition	NOUN
hjic-1157	12	24	[	[	X
hjic-1157	12	25	4	4	NUM
hjic-1157	12	26	,	,	PUNCT
hjic-1157	12	27	5	5	NUM
hjic-1157	12	28	]	]	PUNCT
hjic-1157	12	29	.	.	PUNCT
hjic-1157	13	1	besides	besides	SCONJ
hjic-1157	13	2	isolated	isolated	ADJ
hjic-1157	13	3	enzymes	enzyme	NOUN
hjic-1157	13	4	,	,	PUNCT
hjic-1157	13	5	whole	whole	ADJ
hjic-1157	13	6	cells	cell	NOUN
hjic-1157	13	7	are	be	AUX
hjic-1157	13	8	also	also	ADV
hjic-1157	13	9	being	be	AUX
hjic-1157	13	10	applied	apply	VERB
hjic-1157	13	11	more	more	ADV
hjic-1157	13	12	and	and	CCONJ
hjic-1157	13	13	more	more	ADV
hjic-1157	13	14	often	often	ADV
hjic-1157	13	15	as	as	ADP
hjic-1157	13	16	biocatalysts	biocatalyst	NOUN
hjic-1157	13	17	,	,	PUNCT
hjic-1157	13	18	given	give	VERB
hjic-1157	13	19	the	the	DET
hjic-1157	13	20	disparate	disparate	ADJ
hjic-1157	13	21	attributes	attribute	NOUN
hjic-1157	13	22	of	of	ADP
hjic-1157	13	23	both	both	PRON
hjic-1157	13	24	.	.	PUNCT
hjic-1157	14	1	wholecell	wholecell	NOUN
hjic-1157	14	2	biocatalysts	biocatalyst	NOUN
hjic-1157	14	3	ensure	ensure	VERB
hjic-1157	14	4	the	the	DET
hjic-1157	14	5	optimal	optimal	ADJ
hjic-1157	14	6	environment	environment	NOUN
hjic-1157	14	7	for	for	ADP
hjic-1157	14	8	the	the	DET
hjic-1157	14	9	enzyme	enzyme	NOUN
hjic-1157	14	10	,	,	PUNCT
hjic-1157	14	11	thereby	thereby	ADV
hjic-1157	14	12	providing	provide	VERB
hjic-1157	14	13	a	a	DET
hjic-1157	14	14	quite	quite	ADV
hjic-1157	14	15	stable	stable	ADJ
hjic-1157	14	16	system	system	NOUN
hjic-1157	14	17	.	.	PUNCT
hjic-1157	15	1	furthermore	furthermore	ADV
hjic-1157	15	2	,	,	PUNCT
hjic-1157	15	3	they	they	PRON
hjic-1157	15	4	contain	contain	VERB
hjic-1157	15	5	cofactors	cofactor	NOUN
hjic-1157	15	6	and	and	CCONJ
hjic-1157	15	7	are	be	AUX
hjic-1157	15	8	able	able	ADJ
hjic-1157	15	9	to	to	PART
hjic-1157	15	10	bring	bring	VERB
hjic-1157	15	11	about	about	ADP
hjic-1157	15	12	cofactor	cofactor	NOUN
hjic-1157	15	13	regeneration	regeneration	NOUN
hjic-1157	15	14	without	without	ADP
hjic-1157	15	15	the	the	DET
hjic-1157	15	16	necessary	necessary	ADJ
hjic-1157	15	17	addition	addition	NOUN
hjic-1157	15	18	of	of	ADP
hjic-1157	15	19	any	any	DET
hjic-1157	15	20	other	other	ADJ
hjic-1157	15	21	compounds	compound	NOUN
hjic-1157	15	22	[	[	X
hjic-1157	15	23	6	6	NUM
hjic-1157	15	24	]	]	PUNCT
hjic-1157	15	25	.	.	PUNCT
hjic-1157	16	1	however	however	ADV
hjic-1157	16	2	,	,	PUNCT
hjic-1157	16	3	the	the	DET
hjic-1157	16	4	presence	presence	NOUN
hjic-1157	16	5	of	of	ADP
hjic-1157	16	6	a	a	DET
hjic-1157	16	7	variety	variety	NOUN
hjic-1157	16	8	of	of	ADP
hjic-1157	16	9	enzymes	enzyme	NOUN
hjic-1157	16	10	may	may	AUX
hjic-1157	16	11	lead	lead	VERB
hjic-1157	16	12	to	to	ADP
hjic-1157	16	13	side	side	NOUN
hjic-1157	16	14	reactions	reaction	NOUN
hjic-1157	16	15	.	.	PUNCT
hjic-1157	17	1	also	also	ADV
hjic-1157	17	2	,	,	PUNCT
hjic-1157	17	3	isozymes	isozyme	NOUN
hjic-1157	17	4	with	with	ADP
hjic-1157	17	5	different	different	ADJ
hjic-1157	17	6	enantiomeric	enantiomeric	ADJ
hjic-1157	17	7	preferences	preference	NOUN
hjic-1157	17	8	may	may	AUX
hjic-1157	17	9	lower	lower	VERB
hjic-1157	17	10	the	the	DET
hjic-1157	17	11	overall	overall	ADJ
hjic-1157	17	12	enantiomeric	enantiomeric	ADJ
hjic-1157	17	13	excess	excess	NOUN
hjic-1157	17	14	into	into	ADP
hjic-1157	17	15	recieved	recieve	VERB
hjic-1157	17	16	:	:	PUNCT
hjic-1157	17	17	11	11	NUM
hjic-1157	17	18	march	march	NOUN
hjic-1157	17	19	2022	2022	NUM
hjic-1157	17	20	;	;	PUNCT
hjic-1157	17	21	revised	revise	VERB
hjic-1157	17	22	:	:	PUNCT
hjic-1157	17	23	21	21	NUM
hjic-1157	17	24	march	march	NOUN
hjic-1157	17	25	2022	2022	NUM
hjic-1157	17	26	;	;	PUNCT
hjic-1157	17	27	accepted	accept	VERB
hjic-1157	17	28	:	:	PUNCT
hjic-1157	17	29	21	21	NUM
hjic-1157	17	30	march	march	NOUN
hjic-1157	17	31	2022	2022	NUM
hjic-1157	17	32	*	*	PUNCT
hjic-1157	17	33	correspondence	correspondence	NOUN
hjic-1157	17	34	:	:	PUNCT
hjic-1157	18	1	lajtai-szabo.piroska@mk.uni-pannon.hu	lajtai-szabo.piroska@mk.uni-pannon.hu	VERB
hjic-1157	18	2	the	the	DET
hjic-1157	18	3	bargain	bargain	NOUN
hjic-1157	18	4	[	[	X
hjic-1157	18	5	7	7	NUM
hjic-1157	18	6	]	]	PUNCT
hjic-1157	18	7	.	.	PUNCT
hjic-1157	19	1	unlike	unlike	ADP
hjic-1157	19	2	whole	whole	ADJ
hjic-1157	19	3	-	-	PUNCT
hjic-1157	19	4	cell	cell	NOUN
hjic-1157	19	5	biocatalysts	biocatalyst	NOUN
hjic-1157	19	6	,	,	PUNCT
hjic-1157	19	7	isolated	isolate	VERB
hjic-1157	19	8	enzymes	enzyme	NOUN
hjic-1157	19	9	improve	improve	VERB
hjic-1157	19	10	the	the	DET
hjic-1157	19	11	level	level	NOUN
hjic-1157	19	12	of	of	ADP
hjic-1157	19	13	control	control	NOUN
hjic-1157	19	14	over	over	ADP
hjic-1157	19	15	the	the	DET
hjic-1157	19	16	process	process	NOUN
hjic-1157	19	17	in	in	ADP
hjic-1157	19	18	the	the	DET
hjic-1157	19	19	absence	absence	NOUN
hjic-1157	19	20	of	of	ADP
hjic-1157	19	21	side	side	NOUN
hjic-1157	19	22	reactions	reaction	NOUN
hjic-1157	19	23	,	,	PUNCT
hjic-1157	19	24	thereby	thereby	ADV
hjic-1157	19	25	enhancing	enhance	VERB
hjic-1157	19	26	its	its	PRON
hjic-1157	19	27	reproducibility	reproducibility	NOUN
hjic-1157	19	28	.	.	PUNCT
hjic-1157	20	1	in	in	ADP
hjic-1157	20	2	addition	addition	NOUN
hjic-1157	20	3	,	,	PUNCT
hjic-1157	20	4	inhibition	inhibition	NOUN
hjic-1157	20	5	is	be	AUX
hjic-1157	20	6	less	less	ADV
hjic-1157	20	7	likely	likely	ADJ
hjic-1157	20	8	to	to	PART
hjic-1157	20	9	occur	occur	VERB
hjic-1157	20	10	because	because	SCONJ
hjic-1157	20	11	of	of	ADP
hjic-1157	20	12	the	the	DET
hjic-1157	20	13	greater	great	ADJ
hjic-1157	20	14	degree	degree	NOUN
hjic-1157	20	15	of	of	ADP
hjic-1157	20	16	tolerance	tolerance	NOUN
hjic-1157	20	17	concerning	concern	VERB
hjic-1157	20	18	the	the	DET
hjic-1157	20	19	concentrations	concentration	NOUN
hjic-1157	20	20	of	of	ADP
hjic-1157	20	21	both	both	CCONJ
hjic-1157	20	22	the	the	DET
hjic-1157	20	23	substrate	substrate	NOUN
hjic-1157	20	24	and	and	CCONJ
hjic-1157	20	25	product	product	NOUN
hjic-1157	20	26	.	.	PUNCT
hjic-1157	21	1	on	on	ADP
hjic-1157	21	2	the	the	DET
hjic-1157	21	3	other	other	ADJ
hjic-1157	21	4	hand	hand	NOUN
hjic-1157	21	5	,	,	PUNCT
hjic-1157	21	6	the	the	DET
hjic-1157	21	7	provision	provision	NOUN
hjic-1157	21	8	of	of	ADP
hjic-1157	21	9	a	a	DET
hjic-1157	21	10	cofactor	cofactor	NOUN
hjic-1157	21	11	and	and	CCONJ
hjic-1157	21	12	its	its	PRON
hjic-1157	21	13	regenerating	regenerate	VERB
hjic-1157	21	14	system	system	NOUN
hjic-1157	21	15	significantly	significantly	ADV
hjic-1157	21	16	increases	increase	VERB
hjic-1157	21	17	costs	cost	NOUN
hjic-1157	21	18	.	.	PUNCT
hjic-1157	22	1	in	in	ADP
hjic-1157	22	2	order	order	NOUN
hjic-1157	22	3	to	to	PART
hjic-1157	22	4	choose	choose	VERB
hjic-1157	22	5	the	the	DET
hjic-1157	22	6	optimal	optimal	ADJ
hjic-1157	22	7	catalyst	catalyst	NOUN
hjic-1157	22	8	for	for	ADP
hjic-1157	22	9	a	a	DET
hjic-1157	22	10	given	give	VERB
hjic-1157	22	11	synthesis	synthesis	NOUN
hjic-1157	22	12	,	,	PUNCT
hjic-1157	22	13	a	a	DET
hjic-1157	22	14	detailed	detailed	ADJ
hjic-1157	22	15	comparison	comparison	NOUN
hjic-1157	22	16	of	of	ADP
hjic-1157	22	17	their	their	PRON
hjic-1157	22	18	advantages	advantage	NOUN
hjic-1157	22	19	and	and	CCONJ
hjic-1157	22	20	disadvantages	disadvantage	NOUN
hjic-1157	22	21	,	,	PUNCT
hjic-1157	22	22	e.g.	e.g.	ADV
hjic-1157	22	23	attainable	attainable	ADJ
hjic-1157	22	24	yield	yield	NOUN
hjic-1157	22	25	,	,	PUNCT
hjic-1157	22	26	productivity	productivity	NOUN
hjic-1157	22	27	,	,	PUNCT
hjic-1157	22	28	product	product	NOUN
hjic-1157	22	29	purity	purity	NOUN
hjic-1157	22	30	,	,	PUNCT
hjic-1157	22	31	required	require	VERB
hjic-1157	22	32	downstream	downstream	ADJ
hjic-1157	22	33	processes	process	NOUN
hjic-1157	22	34	and	and	CCONJ
hjic-1157	22	35	costs	cost	NOUN
hjic-1157	22	36	,	,	PUNCT
hjic-1157	22	37	should	should	AUX
hjic-1157	22	38	be	be	AUX
hjic-1157	22	39	made	make	VERB
hjic-1157	22	40	[	[	PUNCT
hjic-1157	22	41	8	8	NUM
hjic-1157	22	42	]	]	PUNCT
hjic-1157	22	43	.	.	PUNCT
hjic-1157	23	1	in	in	ADP
hjic-1157	23	2	this	this	DET
hjic-1157	23	3	research	research	NOUN
hjic-1157	23	4	,	,	PUNCT
hjic-1157	23	5	two	two	NUM
hjic-1157	23	6	types	type	NOUN
hjic-1157	23	7	of	of	ADP
hjic-1157	23	8	alcohol	alcohol	NOUN
hjic-1157	23	9	dehydrogenases	dehydrogenase	NOUN
hjic-1157	23	10	(	(	PUNCT
hjic-1157	23	11	adh	adh	PROPN
hjic-1157	23	12	)	)	PUNCT
hjic-1157	23	13	were	be	AUX
hjic-1157	23	14	investigated	investigate	VERB
hjic-1157	23	15	with	with	ADP
hjic-1157	23	16	regard	regard	NOUN
hjic-1157	23	17	to	to	ADP
hjic-1157	23	18	the	the	DET
hjic-1157	23	19	conversion	conversion	NOUN
hjic-1157	23	20	of	of	ADP
hjic-1157	23	21	racemic	racemic	ADJ
hjic-1157	23	22	2	2	NUM
hjic-1157	23	23	-	-	PUNCT
hjic-1157	23	24	phenylpropionaldehyde	phenylpropionaldehyde	NOUN
hjic-1157	23	25	to	to	ADP
hjic-1157	23	26	(	(	PUNCT
hjic-1157	23	27	s)-2	s)-2	PROPN
hjic-1157	23	28	-	-	PUNCT
hjic-1157	23	29	phenyl-1propanol	phenyl-1propanol	NOUN
hjic-1157	23	30	.	.	PUNCT
hjic-1157	24	1	for	for	ADP
hjic-1157	24	2	the	the	DET
hjic-1157	24	3	catalysis	catalysis	NOUN
hjic-1157	24	4	,	,	PUNCT
hjic-1157	24	5	the	the	DET
hjic-1157	24	6	cofactor	cofactor	NOUN
hjic-1157	24	7	nicotinamide	nicotinamide	NOUN
hjic-1157	24	8	adenine	adenine	ADJ
hjic-1157	24	9	dinucleotide	dinucleotide	NOUN
hjic-1157	24	10	(	(	PUNCT
hjic-1157	24	11	nadh	nadh	NOUN
hjic-1157	24	12	)	)	PUNCT
hjic-1157	24	13	is	be	AUX
hjic-1157	24	14	required	require	VERB
hjic-1157	24	15	by	by	ADP
hjic-1157	24	16	the	the	DET
hjic-1157	24	17	enzyme	enzyme	NOUN
hjic-1157	24	18	which	which	PRON
hjic-1157	24	19	has	have	VERB
hjic-1157	24	20	to	to	PART
hjic-1157	24	21	be	be	AUX
hjic-1157	24	22	regenerated	regenerate	VERB
hjic-1157	24	23	in	in	ADP
hjic-1157	24	24	order	order	NOUN
hjic-1157	24	25	to	to	PART
hjic-1157	24	26	ensure	ensure	VERB
hjic-1157	24	27	continuous	continuous	ADJ
hjic-1157	24	28	product	product	NOUN
hjic-1157	24	29	formation	formation	NOUN
hjic-1157	24	30	.	.	PUNCT
hjic-1157	25	1	ethanol	ethanol	NOUN
hjic-1157	25	2	was	be	AUX
hjic-1157	25	3	applied	apply	VERB
hjic-1157	25	4	as	as	ADP
hjic-1157	25	5	an	an	DET
hjic-1157	25	6	auxiliary	auxiliary	ADJ
hjic-1157	25	7	substrate	substrate	NOUN
hjic-1157	25	8	for	for	ADP
hjic-1157	25	9	the	the	DET
hjic-1157	25	10	regeneration	regeneration	NOUN
hjic-1157	25	11	which	which	PRON
hjic-1157	25	12	was	be	AUX
hjic-1157	25	13	catalysed	catalyse	VERB
hjic-1157	25	14	by	by	ADP
hjic-1157	25	15	the	the	DET
hjic-1157	25	16	adh	adh	NOUN
hjic-1157	25	17	.	.	PUNCT
hjic-1157	26	1	the	the	DET
hjic-1157	26	2	reaction	reaction	NOUN
hjic-1157	26	3	schemes	scheme	NOUN
hjic-1157	26	4	are	be	AUX
hjic-1157	26	5	presented	present	VERB
hjic-1157	26	6	in	in	ADP
hjic-1157	26	7	fig	fig	NOUN
hjic-1157	26	8	.	.	PUNCT
hjic-1157	27	1	1	1	NUM
hjic-1157	27	2	.	.	PUNCT
hjic-1157	27	3	because	because	SCONJ
hjic-1157	27	4	of	of	ADP
hjic-1157	27	5	the	the	DET
hjic-1157	27	6	low	low	ADJ
hjic-1157	27	7	solubility	solubility	NOUN
hjic-1157	27	8	of	of	ADP
hjic-1157	27	9	the	the	DET
hjic-1157	27	10	substrate	substrate	NOUN
hjic-1157	27	11	and	and	CCONJ
hjic-1157	27	12	the	the	DET
hjic-1157	27	13	product	product	NOUN
hjic-1157	27	14	in	in	ADP
hjic-1157	27	15	aqueous	aqueous	ADJ
hjic-1157	27	16	media	medium	NOUN
hjic-1157	27	17	,	,	PUNCT
hjic-1157	27	18	a	a	DET
hjic-1157	27	19	two	two	NUM
hjic-1157	27	20	-	-	PUNCT
hjic-1157	27	21	phase	phase	NOUN
hjic-1157	27	22	system	system	NOUN
hjic-1157	27	23	was	be	AUX
hjic-1157	27	24	applied	apply	VERB
hjic-1157	27	25	.	.	PUNCT
hjic-1157	28	1	saccharomyces	saccharomyce	NOUN
hjic-1157	28	2	cerevisiae	cerevisiae	NOUN
hjic-1157	28	3	was	be	AUX
hjic-1157	28	4	applied	apply	VERB
hjic-1157	28	5	in	in	ADP
hjic-1157	28	6	dried	dry	VERB
hjic-1157	28	7	form	form	NOUN
hjic-1157	28	8	(	(	PUNCT
hjic-1157	28	9	instant	instant	NOUN
hjic-1157	28	10	baker	baker	NOUN
hjic-1157	28	11	’s	’s	PART
hjic-1157	28	12	dry	dry	ADJ
hjic-1157	28	13	yeast	yeast	NOUN
hjic-1157	28	14	)	)	PUNCT
hjic-1157	28	15	as	as	ADP
hjic-1157	28	16	a	a	DET
hjic-1157	28	17	whole	whole	ADJ
hjic-1157	28	18	-	-	PUNCT
hjic-1157	28	19	cell	cell	NOUN
hjic-1157	28	20	biocatalyst	biocatalyst	NOUN
hjic-1157	28	21	.	.	PUNCT
hjic-1157	29	1	over	over	ADP
hjic-1157	29	2	recent	recent	ADJ
hjic-1157	29	3	decades	decade	NOUN
hjic-1157	29	4	,	,	PUNCT
hjic-1157	29	5	both	both	CCONJ
hjic-1157	29	6	wild	wild	ADJ
hjic-1157	29	7	and	and	CCONJ
hjic-1157	29	8	genetically	genetically	ADV
hjic-1157	29	9	modified	modify	VERB
hjic-1157	29	10	strains	strain	NOUN
hjic-1157	29	11	of	of	ADP
hjic-1157	29	12	yeast	yeast	NOUN
hjic-1157	29	13	have	have	AUX
hjic-1157	29	14	been	be	AUX
hjic-1157	29	15	gaining	gain	VERB
hjic-1157	29	16	more	more	ADJ
hjic-1157	29	17	and	and	CCONJ
hjic-1157	29	18	more	more	ADJ
hjic-1157	29	19	attention	attention	NOUN
hjic-1157	29	20	as	as	ADP
hjic-1157	29	21	biocatalysts	biocatalyst	NOUN
hjic-1157	29	22	in	in	ADP
hjic-1157	29	23	the	the	DET
hjic-1157	29	24	production	production	NOUN
hjic-1157	29	25	of	of	ADP
hjic-1157	29	26	fine	fine	ADJ
hjic-1157	29	27	chemicals	chemical	NOUN
hjic-1157	29	28	[	[	X
hjic-1157	29	29	7	7	NUM
hjic-1157	29	30	]	]	PUNCT
hjic-1157	29	31	.	.	PUNCT
hjic-1157	30	1	although	although	SCONJ
hjic-1157	30	2	(	(	PUNCT
hjic-1157	30	3	s)-alcohol	s)-alcohol	NOUN
hjic-1157	30	4	is	be	AUX
hjic-1157	30	5	generally	generally	ADV
hjic-1157	30	6	the	the	DET
hjic-1157	30	7	predominant	predominant	ADJ
hjic-1157	30	8	https://doi.org/10.33927/hjic-2022-05	https://doi.org/10.33927/hjic-2022-05	PROPN
hjic-1157	30	9	mailto:lajtai-szabo.piroska@mk.uni-pannon.hu	mailto:lajtai-szabo.piroska@mk.uni-pannon.hu	PROPN
hjic-1157	30	10	24	24	NUM
hjic-1157	30	11	lajtai	lajtai	NOUN
hjic-1157	30	12	-	-	PUNCT
hjic-1157	30	13	szabó	szabó	NOUN
hjic-1157	30	14	,	,	PUNCT
hjic-1157	30	15	bagó	bagó	PROPN
hjic-1157	30	16	and	and	CCONJ
hjic-1157	30	17	nemestóthy	nemestóthy	ADJ
hjic-1157	30	18	figure	figure	NOUN
hjic-1157	30	19	1	1	NUM
hjic-1157	30	20	:	:	PUNCT
hjic-1157	30	21	reaction	reaction	NOUN
hjic-1157	30	22	scheme	scheme	NOUN
hjic-1157	30	23	enantiomer	enantiomer	NOUN
hjic-1157	30	24	in	in	ADP
hjic-1157	30	25	the	the	DET
hjic-1157	30	26	reduction	reduction	NOUN
hjic-1157	30	27	of	of	ADP
hjic-1157	30	28	racemic	racemic	ADJ
hjic-1157	30	29	carboxylic	carboxylic	ADJ
hjic-1157	30	30	acid	acid	NOUN
hjic-1157	30	31	compounds	compound	NOUN
hjic-1157	30	32	by	by	ADP
hjic-1157	30	33	applying	apply	VERB
hjic-1157	30	34	yeast	yeast	NOUN
hjic-1157	30	35	[	[	X
hjic-1157	30	36	6	6	NUM
hjic-1157	30	37	]	]	PUNCT
hjic-1157	30	38	,	,	PUNCT
hjic-1157	30	39	this	this	PRON
hjic-1157	30	40	is	be	AUX
hjic-1157	30	41	dependent	dependent	ADJ
hjic-1157	30	42	on	on	ADP
hjic-1157	30	43	the	the	DET
hjic-1157	30	44	given	give	VERB
hjic-1157	30	45	substrate	substrate	NOUN
hjic-1157	30	46	[	[	X
hjic-1157	30	47	9	9	NUM
hjic-1157	30	48	]	]	PUNCT
hjic-1157	30	49	.	.	PUNCT
hjic-1157	31	1	our	our	PRON
hjic-1157	31	2	second	second	ADJ
hjic-1157	31	3	catalyst	catalyst	NOUN
hjic-1157	31	4	was	be	AUX
hjic-1157	31	5	recombinant	recombinant	ADJ
hjic-1157	31	6	horse	horse	NOUN
hjic-1157	31	7	-	-	PUNCT
hjic-1157	31	8	liver	liver	NOUN
hjic-1157	31	9	adh	adh	NOUN
hjic-1157	31	10	expressed	express	VERB
hjic-1157	31	11	in	in	ADP
hjic-1157	31	12	e.	e.	PROPN
hjic-1157	31	13	coli	coli	PROPN
hjic-1157	31	14	.	.	PUNCT
hjic-1157	32	1	isolated	isolate	VERB
hjic-1157	32	2	recombinant	recombinant	ADJ
hjic-1157	32	3	horse	horse	NOUN
hjic-1157	32	4	-	-	PUNCT
hjic-1157	32	5	liver	liver	NOUN
hjic-1157	32	6	adh	adh	NOUN
hjic-1157	32	7	is	be	AUX
hjic-1157	32	8	frequently	frequently	ADV
hjic-1157	32	9	applied	apply	VERB
hjic-1157	32	10	for	for	ADP
hjic-1157	32	11	asymmetric	asymmetric	ADJ
hjic-1157	32	12	syntheses	synthesis	NOUN
hjic-1157	32	13	[	[	X
hjic-1157	32	14	10–12	10–12	NUM
hjic-1157	32	15	]	]	X
hjic-1157	32	16	,	,	PUNCT
hjic-1157	32	17	moreover	moreover	ADV
hjic-1157	32	18	,	,	PUNCT
hjic-1157	32	19	its	its	PRON
hjic-1157	32	20	variant	variant	NOUN
hjic-1157	32	21	expressed	express	VERB
hjic-1157	32	22	in	in	ADP
hjic-1157	32	23	bacteria	bacteria	NOUN
hjic-1157	32	24	can	can	AUX
hjic-1157	32	25	be	be	AUX
hjic-1157	32	26	a	a	DET
hjic-1157	32	27	cheaper	cheap	ADJ
hjic-1157	32	28	and	and	CCONJ
hjic-1157	32	29	more	more	ADV
hjic-1157	32	30	accessible	accessible	ADJ
hjic-1157	32	31	alternative	alternative	NOUN
hjic-1157	32	32	.	.	PUNCT
hjic-1157	33	1	the	the	DET
hjic-1157	33	2	aim	aim	NOUN
hjic-1157	33	3	of	of	ADP
hjic-1157	33	4	this	this	DET
hjic-1157	33	5	research	research	NOUN
hjic-1157	33	6	was	be	AUX
hjic-1157	33	7	to	to	PART
hjic-1157	33	8	characterise	characterise	VERB
hjic-1157	33	9	the	the	DET
hjic-1157	33	10	aforementioned	aforementioned	ADJ
hjic-1157	33	11	biocatalyst	biocatalyst	NOUN
hjic-1157	33	12	in	in	ADP
hjic-1157	33	13	terms	term	NOUN
hjic-1157	33	14	of	of	ADP
hjic-1157	33	15	activity	activity	NOUN
hjic-1157	33	16	,	,	PUNCT
hjic-1157	33	17	kinetics	kinetic	NOUN
hjic-1157	33	18	and	and	CCONJ
hjic-1157	33	19	enantioselectivity	enantioselectivity	NOUN
hjic-1157	33	20	,	,	PUNCT
hjic-1157	33	21	thereby	thereby	ADV
hjic-1157	33	22	enabling	enable	VERB
hjic-1157	33	23	their	their	PRON
hjic-1157	33	24	critical	critical	ADJ
hjic-1157	33	25	comparison	comparison	NOUN
hjic-1157	33	26	.	.	PUNCT
hjic-1157	34	1	in	in	ADP
hjic-1157	34	2	addition	addition	NOUN
hjic-1157	34	3	,	,	PUNCT
hjic-1157	34	4	mass	mass	ADJ
hjic-1157	34	5	transfer	transfer	NOUN
hjic-1157	34	6	through	through	ADP
hjic-1157	34	7	the	the	DET
hjic-1157	34	8	organic	organic	ADJ
hjic-1157	34	9	-	-	PUNCT
hjic-1157	34	10	water	water	NOUN
hjic-1157	34	11	interphase	interphase	NOUN
hjic-1157	34	12	was	be	AUX
hjic-1157	34	13	also	also	ADV
hjic-1157	34	14	investigated	investigate	VERB
hjic-1157	34	15	in	in	ADP
hjic-1157	34	16	order	order	NOUN
hjic-1157	34	17	to	to	PART
hjic-1157	34	18	characterise	characterise	VERB
hjic-1157	34	19	the	the	DET
hjic-1157	34	20	relationship	relationship	NOUN
hjic-1157	34	21	between	between	ADP
hjic-1157	34	22	the	the	DET
hjic-1157	34	23	rates	rate	NOUN
hjic-1157	34	24	of	of	ADP
hjic-1157	34	25	each	each	DET
hjic-1157	34	26	step	step	NOUN
hjic-1157	34	27	.	.	PUNCT
hjic-1157	35	1	2	2	X
hjic-1157	35	2	.	.	X
hjic-1157	35	3	experimental	experimental	ADJ
hjic-1157	35	4	methods	method	NOUN
hjic-1157	35	5	2.1	2.1	NUM
hjic-1157	35	6	applied	apply	VERB
hjic-1157	35	7	chemicals	chemical	NOUN
hjic-1157	35	8	all	all	DET
hjic-1157	35	9	chemicals	chemical	NOUN
hjic-1157	35	10	were	be	AUX
hjic-1157	35	11	commercially	commercially	ADV
hjic-1157	35	12	available	available	ADJ
hjic-1157	35	13	and	and	CCONJ
hjic-1157	35	14	used	use	VERB
hjic-1157	35	15	without	without	ADP
hjic-1157	35	16	further	further	ADJ
hjic-1157	35	17	purification	purification	NOUN
hjic-1157	35	18	.	.	PUNCT
hjic-1157	36	1	diisopropyl	diisopropyl	NOUN
hjic-1157	36	2	ether	ether	NOUN
hjic-1157	36	3	(	(	PUNCT
hjic-1157	36	4	puriss	puriss	ADJ
hjic-1157	36	5	)	)	PUNCT
hjic-1157	36	6	,	,	PUNCT
hjic-1157	36	7	ethyl	ethyl	PROPN
hjic-1157	36	8	alcohol	alcohol	PROPN
hjic-1157	36	9	(	(	PUNCT
hjic-1157	36	10	a.r	a.r	PROPN
hjic-1157	36	11	.	.	PROPN
hjic-1157	36	12	)	)	PUNCT
hjic-1157	36	13	,	,	PUNCT
hjic-1157	36	14	dodecane	dodecane	PROPN
hjic-1157	36	15	(	(	PUNCT
hjic-1157	36	16	a.r	a.r	PROPN
hjic-1157	36	17	.	.	PROPN
hjic-1157	36	18	)	)	PUNCT
hjic-1157	36	19	,	,	PUNCT
hjic-1157	36	20	trifluoroacetic	trifluoroacetic	ADJ
hjic-1157	36	21	anhydride	anhydride	NOUN
hjic-1157	36	22	(	(	PUNCT
hjic-1157	36	23	98	98	NUM
hjic-1157	36	24	%	%	NOUN
hjic-1157	36	25	)	)	PUNCT
hjic-1157	36	26	,	,	PUNCT
hjic-1157	36	27	racemic	racemic	ADJ
hjic-1157	36	28	2	2	NUM
hjic-1157	36	29	-	-	PUNCT
hjic-1157	36	30	phenylpropionaldehyde	phenylpropionaldehyde	NOUN
hjic-1157	36	31	(	(	PUNCT
hjic-1157	36	32	98	98	NUM
hjic-1157	36	33	%	%	NOUN
hjic-1157	36	34	)	)	PUNCT
hjic-1157	36	35	and	and	CCONJ
hjic-1157	36	36	s-(2)-phenyl-1	s-(2)-phenyl-1	NOUN
hjic-1157	36	37	-	-	PUNCT
hjic-1157	36	38	propanol	propanol	NOUN
hjic-1157	36	39	(	(	PUNCT
hjic-1157	36	40	97	97	NUM
hjic-1157	36	41	%	%	NOUN
hjic-1157	36	42	)	)	PUNCT
hjic-1157	36	43	were	be	AUX
hjic-1157	36	44	purchased	purchase	VERB
hjic-1157	36	45	from	from	ADP
hjic-1157	36	46	sigma	sigma	PROPN
hjic-1157	36	47	-	-	PUNCT
hjic-1157	36	48	aldrich	aldrich	NOUN
hjic-1157	36	49	.	.	PUNCT
hjic-1157	37	1	recombinant	recombinant	ADJ
hjic-1157	37	2	horse	horse	NOUN
hjic-1157	37	3	-	-	PUNCT
hjic-1157	37	4	liver	liver	NOUN
hjic-1157	37	5	alcohol	alcohol	NOUN
hjic-1157	37	6	dehydrogenase	dehydrogenase	NOUN
hjic-1157	37	7	(	(	PUNCT
hjic-1157	37	8	expressed	express	VERB
hjic-1157	37	9	in	in	ADP
hjic-1157	37	10	e.	e.	PROPN
hjic-1157	37	11	coli	coli	PROPN
hjic-1157	37	12	)	)	PUNCT
hjic-1157	37	13	as	as	ADV
hjic-1157	37	14	well	well	ADV
hjic-1157	37	15	as	as	ADP
hjic-1157	37	16	lyophilised	lyophilise	VERB
hjic-1157	37	17	powder	powder	NOUN
hjic-1157	37	18	(	(	PUNCT
hjic-1157	37	19	1.5	1.5	NUM
hjic-1157	37	20	u	u	NOUN
hjic-1157	37	21	/	/	SYM
hjic-1157	37	22	mg	mg	PROPN
hjic-1157	37	23	)	)	PUNCT
hjic-1157	37	24	and	and	CCONJ
hjic-1157	37	25	β	β	NOUN
hjic-1157	37	26	-	-	NOUN
hjic-1157	37	27	nicotinamide	nicotinamide	NOUN
hjic-1157	37	28	adenine	adenine	ADJ
hjic-1157	37	29	dinucleotide	dinucleotide	NOUN
hjic-1157	37	30	(	(	PUNCT
hjic-1157	37	31	sodium	sodium	NOUN
hjic-1157	37	32	salt	salt	NOUN
hjic-1157	37	33	,	,	PUNCT
hjic-1157	37	34	98	98	NUM
hjic-1157	37	35	%	%	NOUN
hjic-1157	37	36	)	)	PUNCT
hjic-1157	37	37	were	be	AUX
hjic-1157	37	38	obtained	obtain	VERB
hjic-1157	37	39	from	from	ADP
hjic-1157	37	40	sigmaaldrich	sigmaaldrich	NOUN
hjic-1157	37	41	and	and	CCONJ
hjic-1157	37	42	thermo	thermo	PROPN
hjic-1157	37	43	fisher	fisher	PROPN
hjic-1157	37	44	scientific	scientific	PROPN
hjic-1157	37	45	,	,	PUNCT
hjic-1157	37	46	respectively	respectively	ADV
hjic-1157	37	47	.	.	PUNCT
hjic-1157	38	1	k2hpo4	k2hpo4	PROPN
hjic-1157	38	2	,	,	PUNCT
hjic-1157	38	3	kh2po4	kh2po4	PROPN
hjic-1157	38	4	and	and	CCONJ
hjic-1157	38	5	na2co3	na2co3	PROPN
hjic-1157	38	6	were	be	AUX
hjic-1157	38	7	purchased	purchase	VERB
hjic-1157	38	8	from	from	ADP
hjic-1157	38	9	vwr	vwr	PROPN
hjic-1157	38	10	,	,	PUNCT
hjic-1157	38	11	while	while	SCONJ
hjic-1157	38	12	instant	instant	ADJ
hjic-1157	38	13	baker	baker	PROPN
hjic-1157	38	14	’s	’s	PART
hjic-1157	38	15	dry	dry	ADJ
hjic-1157	38	16	yeast	yeast	NOUN
hjic-1157	38	17	was	be	AUX
hjic-1157	38	18	purchased	purchase	VERB
hjic-1157	38	19	from	from	ADP
hjic-1157	38	20	a	a	DET
hjic-1157	38	21	local	local	ADJ
hjic-1157	38	22	store	store	NOUN
hjic-1157	38	23	.	.	PUNCT
hjic-1157	39	1	2.2	2.2	NUM
hjic-1157	39	2	activity	activity	NOUN
hjic-1157	39	3	measurements	measurement	NOUN
hjic-1157	39	4	a	a	DET
hjic-1157	39	5	spectrophotometric	spectrophotometric	ADJ
hjic-1157	39	6	method	method	NOUN
hjic-1157	39	7	was	be	AUX
hjic-1157	39	8	used	use	VERB
hjic-1157	39	9	to	to	PART
hjic-1157	39	10	determine	determine	VERB
hjic-1157	39	11	the	the	DET
hjic-1157	39	12	catalytic	catalytic	ADJ
hjic-1157	39	13	activity	activity	NOUN
hjic-1157	39	14	characteristic	characteristic	NOUN
hjic-1157	39	15	of	of	ADP
hjic-1157	39	16	cofactor	cofactor	NOUN
hjic-1157	39	17	regeneration	regeneration	NOUN
hjic-1157	39	18	.	.	PUNCT
hjic-1157	40	1	given	give	VERB
hjic-1157	40	2	that	that	SCONJ
hjic-1157	40	3	the	the	DET
hjic-1157	40	4	maximum	maximum	ADJ
hjic-1157	40	5	adsorption	adsorption	NOUN
hjic-1157	40	6	of	of	ADP
hjic-1157	40	7	nadh	nadh	NOUN
hjic-1157	40	8	is	be	AUX
hjic-1157	40	9	at	at	ADP
hjic-1157	40	10	340	340	NUM
hjic-1157	40	11	nm	nm	NOUN
hjic-1157	40	12	while	while	SCONJ
hjic-1157	40	13	that	that	PRON
hjic-1157	40	14	of	of	ADP
hjic-1157	40	15	nad+	nad+	PROPN
hjic-1157	40	16	is	be	AUX
hjic-1157	40	17	negligible	negligible	ADJ
hjic-1157	40	18	at	at	ADP
hjic-1157	40	19	this	this	DET
hjic-1157	40	20	wavelength	wavelength	NOUN
hjic-1157	40	21	,	,	PUNCT
hjic-1157	40	22	conversion	conversion	NOUN
hjic-1157	40	23	of	of	ADP
hjic-1157	40	24	the	the	DET
hjic-1157	40	25	cofactor	cofactor	NOUN
hjic-1157	40	26	can	can	AUX
hjic-1157	40	27	be	be	AUX
hjic-1157	40	28	followed	follow	VERB
hjic-1157	40	29	by	by	ADP
hjic-1157	40	30	the	the	DET
hjic-1157	40	31	change	change	NOUN
hjic-1157	40	32	in	in	ADP
hjic-1157	40	33	the	the	DET
hjic-1157	40	34	wavelength	wavelength	NOUN
hjic-1157	40	35	of	of	ADP
hjic-1157	40	36	adsorption	adsorption	NOUN
hjic-1157	40	37	.	.	PUNCT
hjic-1157	41	1	in	in	ADP
hjic-1157	41	2	the	the	DET
hjic-1157	41	3	case	case	NOUN
hjic-1157	41	4	of	of	ADP
hjic-1157	41	5	isolated	isolated	ADJ
hjic-1157	41	6	adh	adh	NOUN
hjic-1157	41	7	,	,	PUNCT
hjic-1157	41	8	10	10	NUM
hjic-1157	41	9	µl	µl	NOUN
hjic-1157	41	10	of	of	ADP
hjic-1157	41	11	enzyme	enzyme	NOUN
hjic-1157	41	12	solution	solution	NOUN
hjic-1157	41	13	(	(	PUNCT
hjic-1157	41	14	10	10	NUM
hjic-1157	41	15	mg	mg	NUM
hjic-1157	41	16	/	/	SYM
hjic-1157	41	17	ml	ml	NOUN
hjic-1157	41	18	)	)	PUNCT
hjic-1157	41	19	,	,	PUNCT
hjic-1157	41	20	600	600	NUM
hjic-1157	41	21	µl	µl	NOUN
hjic-1157	41	22	of	of	ADP
hjic-1157	41	23	nad+	nad+	PROPN
hjic-1157	41	24	solution	solution	NOUN
hjic-1157	41	25	(	(	PUNCT
hjic-1157	41	26	4	4	NUM
hjic-1157	41	27	mg	mg	NUM
hjic-1157	41	28	/	/	SYM
hjic-1157	41	29	ml	ml	NOUN
hjic-1157	41	30	)	)	PUNCT
hjic-1157	41	31	and	and	CCONJ
hjic-1157	41	32	1240	1240	NUM
hjic-1157	41	33	µl	µl	NOUN
hjic-1157	41	34	of	of	ADP
hjic-1157	41	35	buffer	buffer	NOUN
hjic-1157	41	36	solution	solution	NOUN
hjic-1157	41	37	were	be	AUX
hjic-1157	41	38	mixed	mix	VERB
hjic-1157	41	39	in	in	ADP
hjic-1157	41	40	a	a	DET
hjic-1157	41	41	quartz	quartz	NOUN
hjic-1157	41	42	cuvette	cuvette	NOUN
hjic-1157	41	43	.	.	PUNCT
hjic-1157	42	1	the	the	DET
hjic-1157	42	2	reaction	reaction	NOUN
hjic-1157	42	3	was	be	AUX
hjic-1157	42	4	initiated	initiate	VERB
hjic-1157	42	5	by	by	ADP
hjic-1157	42	6	the	the	DET
hjic-1157	42	7	addition	addition	NOUN
hjic-1157	42	8	of	of	ADP
hjic-1157	42	9	150	150	NUM
hjic-1157	42	10	µl	µl	PART
hjic-1157	42	11	cc	cc	PROPN
hjic-1157	42	12	.	.	PROPN
hjic-1157	42	13	of	of	ADP
hjic-1157	42	14	ethyl	ethyl	PROPN
hjic-1157	42	15	alcohol	alcohol	NOUN
hjic-1157	42	16	and	and	CCONJ
hjic-1157	42	17	the	the	DET
hjic-1157	42	18	change	change	NOUN
hjic-1157	42	19	in	in	ADP
hjic-1157	42	20	absorbance	absorbance	NOUN
hjic-1157	42	21	was	be	AUX
hjic-1157	42	22	measured	measure	VERB
hjic-1157	42	23	at	at	ADP
hjic-1157	42	24	340	340	NUM
hjic-1157	42	25	nm	nm	NOUN
hjic-1157	42	26	by	by	ADP
hjic-1157	42	27	a	a	DET
hjic-1157	42	28	shimadzu	shimadzu	ADJ
hjic-1157	42	29	uv-1800	uv-1800	NOUN
hjic-1157	42	30	ultraviolet	ultraviolet	NOUN
hjic-1157	42	31	-	-	PUNCT
hjic-1157	42	32	visible	visible	ADJ
hjic-1157	42	33	spectrophotometer	spectrophotometer	NOUN
hjic-1157	42	34	.	.	PUNCT
hjic-1157	43	1	in	in	ADP
hjic-1157	43	2	the	the	DET
hjic-1157	43	3	case	case	NOUN
hjic-1157	43	4	of	of	ADP
hjic-1157	43	5	the	the	DET
hjic-1157	43	6	whole	whole	ADJ
hjic-1157	43	7	-	-	PUNCT
hjic-1157	43	8	cell	cell	NOUN
hjic-1157	43	9	biocatalyst	biocatalyst	NOUN
hjic-1157	43	10	,	,	PUNCT
hjic-1157	43	11	10	10	NUM
hjic-1157	43	12	µl	µl	NOUN
hjic-1157	43	13	of	of	ADP
hjic-1157	43	14	an	an	DET
hjic-1157	43	15	instant	instant	ADJ
hjic-1157	43	16	yeast	yeast	NOUN
hjic-1157	43	17	suspension	suspension	NOUN
hjic-1157	43	18	(	(	PUNCT
hjic-1157	43	19	10	10	NUM
hjic-1157	43	20	mg	mg	NUM
hjic-1157	43	21	/	/	SYM
hjic-1157	43	22	ml	ml	NOUN
hjic-1157	43	23	)	)	PUNCT
hjic-1157	43	24	was	be	AUX
hjic-1157	43	25	applied	apply	VERB
hjic-1157	43	26	instead	instead	ADV
hjic-1157	43	27	of	of	ADP
hjic-1157	43	28	an	an	DET
hjic-1157	43	29	enzyme	enzyme	NOUN
hjic-1157	43	30	solution	solution	NOUN
hjic-1157	43	31	.	.	PUNCT
hjic-1157	44	1	the	the	DET
hjic-1157	44	2	catalytic	catalytic	ADJ
hjic-1157	44	3	activity	activity	NOUN
hjic-1157	44	4	was	be	AUX
hjic-1157	44	5	calculated	calculate	VERB
hjic-1157	44	6	based	base	VERB
hjic-1157	44	7	on	on	ADP
hjic-1157	44	8	the	the	DET
hjic-1157	44	9	following	follow	VERB
hjic-1157	44	10	equation	equation	NOUN
hjic-1157	44	11	:	:	PUNCT
hjic-1157	44	12	va	va	PROPN
hjic-1157	44	13	=	=	SYM
hjic-1157	44	14	da	da	PROPN
hjic-1157	44	15	dt	dt	X
hjic-1157	44	16	vcuvette	vcuvette	NOUN
hjic-1157	44	17	εd	εd	ADP
hjic-1157	44	18	venzyme	venzyme	NOUN
hjic-1157	44	19	h	h	NOUN
hjic-1157	44	20	(	(	PUNCT
hjic-1157	44	21	1	1	NUM
hjic-1157	44	22	)	)	PUNCT
hjic-1157	44	23	where	where	SCONJ
hjic-1157	44	24	va	va	PROPN
hjic-1157	44	25	denotes	denote	VERB
hjic-1157	44	26	the	the	DET
hjic-1157	44	27	volume	volume	NOUN
hjic-1157	44	28	activity	activity	NOUN
hjic-1157	45	1	[	[	X
hjic-1157	45	2	u	u	X
hjic-1157	45	3	/	/	SYM
hjic-1157	45	4	cm3	cm3	NOUN
hjic-1157	45	5	]	]	PUNCT
hjic-1157	45	6	,	,	PUNCT
hjic-1157	45	7	da	da	PROPN
hjic-1157	45	8	dt	dt	PROPN
hjic-1157	45	9	represents	represent	VERB
hjic-1157	45	10	the	the	DET
hjic-1157	45	11	gradient	gradient	NOUN
hjic-1157	45	12	of	of	ADP
hjic-1157	45	13	the	the	DET
hjic-1157	45	14	line	line	NOUN
hjic-1157	45	15	(	(	PUNCT
hjic-1157	45	16	by	by	ADP
hjic-1157	45	17	plotting	plot	VERB
hjic-1157	45	18	absorbance	absorbance	NOUN
hjic-1157	45	19	vs.	vs.	ADP
hjic-1157	45	20	time	time	NOUN
hjic-1157	45	21	)	)	PUNCT
hjic-1157	45	22	,	,	PUNCT
hjic-1157	45	23	vcuvette	vcuvette	NOUN
hjic-1157	45	24	stands	stand	VERB
hjic-1157	45	25	for	for	ADP
hjic-1157	45	26	the	the	DET
hjic-1157	45	27	volume	volume	NOUN
hjic-1157	45	28	of	of	ADP
hjic-1157	45	29	the	the	DET
hjic-1157	45	30	mixture	mixture	NOUN
hjic-1157	45	31	[	[	X
hjic-1157	45	32	cm3	cm3	NOUN
hjic-1157	45	33	]	]	PUNCT
hjic-1157	45	34	,	,	PUNCT
hjic-1157	45	35	ε	ε	PROPN
hjic-1157	45	36	refers	refer	VERB
hjic-1157	45	37	to	to	ADP
hjic-1157	45	38	the	the	DET
hjic-1157	45	39	molar	molar	ADJ
hjic-1157	45	40	extinction	extinction	NOUN
hjic-1157	45	41	coefficient	coefficient	NOUN
hjic-1157	45	42	of	of	ADP
hjic-1157	45	43	nadh	nadh	NOUN
hjic-1157	45	44	at	at	ADP
hjic-1157	45	45	340	340	NUM
hjic-1157	45	46	nm	nm	NOUN
hjic-1157	45	47	[	[	X
hjic-1157	45	48	6.22	6.22	NUM
hjic-1157	45	49	cm2/µmol	cm2/µmol	NOUN
hjic-1157	45	50	]	]	PUNCT
hjic-1157	45	51	,	,	PUNCT
hjic-1157	45	52	d	d	X
hjic-1157	45	53	is	be	AUX
hjic-1157	45	54	the	the	DET
hjic-1157	45	55	width	width	NOUN
hjic-1157	45	56	of	of	ADP
hjic-1157	45	57	the	the	DET
hjic-1157	45	58	cuvette	cuvette	NOUN
hjic-1157	46	1	[	[	X
hjic-1157	46	2	1	1	NUM
hjic-1157	46	3	cm	cm	NOUN
hjic-1157	46	4	]	]	PUNCT
hjic-1157	46	5	,	,	PUNCT
hjic-1157	46	6	venzyme	venzyme	NOUN
hjic-1157	46	7	denotes	denote	VERB
hjic-1157	46	8	the	the	DET
hjic-1157	46	9	volume	volume	NOUN
hjic-1157	46	10	of	of	ADP
hjic-1157	46	11	the	the	DET
hjic-1157	46	12	enzyme	enzyme	NOUN
hjic-1157	46	13	solution	solution	NOUN
hjic-1157	46	14	[	[	X
hjic-1157	46	15	cm3	cm3	NOUN
hjic-1157	46	16	]	]	PUNCT
hjic-1157	46	17	and	and	CCONJ
hjic-1157	46	18	h	h	NOUN
hjic-1157	46	19	represents	represent	VERB
hjic-1157	46	20	dilution	dilution	NOUN
hjic-1157	46	21	.	.	PUNCT
hjic-1157	47	1	the	the	DET
hjic-1157	47	2	catalytic	catalytic	ADJ
hjic-1157	47	3	activity	activity	NOUN
hjic-1157	47	4	characteristic	characteristic	NOUN
hjic-1157	47	5	of	of	ADP
hjic-1157	47	6	the	the	DET
hjic-1157	47	7	conversion	conversion	NOUN
hjic-1157	47	8	of	of	ADP
hjic-1157	47	9	2	2	NUM
hjic-1157	47	10	-	-	PUNCT
hjic-1157	47	11	phenylpropionaldehyde	phenylpropionaldehyde	NOUN
hjic-1157	47	12	can	can	AUX
hjic-1157	47	13	not	not	PART
hjic-1157	47	14	be	be	AUX
hjic-1157	47	15	measured	measure	VERB
hjic-1157	47	16	by	by	ADP
hjic-1157	47	17	a	a	DET
hjic-1157	47	18	spectrophotometer	spectrophotometer	NOUN
hjic-1157	47	19	since	since	SCONJ
hjic-1157	47	20	the	the	DET
hjic-1157	47	21	reaction	reaction	NOUN
hjic-1157	47	22	mixture	mixture	NOUN
hjic-1157	47	23	consists	consist	VERB
hjic-1157	47	24	of	of	ADP
hjic-1157	47	25	two	two	NUM
hjic-1157	47	26	phases	phase	NOUN
hjic-1157	47	27	.	.	PUNCT
hjic-1157	48	1	therefore	therefore	ADV
hjic-1157	48	2	,	,	PUNCT
hjic-1157	48	3	the	the	DET
hjic-1157	48	4	catalytic	catalytic	ADJ
hjic-1157	48	5	activity	activity	NOUN
hjic-1157	48	6	characteristic	characteristic	NOUN
hjic-1157	48	7	of	of	ADP
hjic-1157	48	8	the	the	DET
hjic-1157	48	9	whole	whole	ADJ
hjic-1157	48	10	process	process	NOUN
hjic-1157	48	11	(	(	PUNCT
hjic-1157	48	12	substrate	substrate	NOUN
hjic-1157	48	13	conversion	conversion	NOUN
hjic-1157	48	14	,	,	PUNCT
hjic-1157	48	15	cofactor	cofactor	NOUN
hjic-1157	48	16	regeneration	regeneration	NOUN
hjic-1157	48	17	and	and	CCONJ
hjic-1157	48	18	mass	mass	NOUN
hjic-1157	48	19	transfer	transfer	NOUN
hjic-1157	48	20	through	through	ADP
hjic-1157	48	21	the	the	DET
hjic-1157	48	22	organic	organic	ADJ
hjic-1157	48	23	-	-	PUNCT
hjic-1157	48	24	water	water	NOUN
hjic-1157	48	25	interface	interface	NOUN
hjic-1157	48	26	)	)	PUNCT
hjic-1157	48	27	was	be	AUX
hjic-1157	48	28	calculated	calculate	VERB
hjic-1157	48	29	from	from	ADP
hjic-1157	48	30	the	the	DET
hjic-1157	48	31	results	result	NOUN
hjic-1157	48	32	gained	gain	VERB
hjic-1157	48	33	by	by	ADP
hjic-1157	48	34	measuring	measure	VERB
hjic-1157	48	35	the	the	DET
hjic-1157	48	36	kinetics	kinetic	NOUN
hjic-1157	48	37	,	,	PUNCT
hjic-1157	48	38	as	as	SCONJ
hjic-1157	48	39	described	describe	VERB
hjic-1157	48	40	in	in	ADP
hjic-1157	48	41	sec	sec	PROPN
hjic-1157	48	42	.	.	PROPN
hjic-1157	49	1	2.4	2.4	NUM
hjic-1157	49	2	.	.	X
hjic-1157	50	1	2.3	2.3	NUM
hjic-1157	50	2	mass	mass	ADJ
hjic-1157	50	3	-	-	PUNCT
hjic-1157	50	4	transfer	transfer	NOUN
hjic-1157	50	5	rate	rate	NOUN
hjic-1157	50	6	since	since	SCONJ
hjic-1157	50	7	experimental	experimental	ADJ
hjic-1157	50	8	conditions	condition	NOUN
hjic-1157	50	9	applied	apply	VERB
hjic-1157	50	10	by	by	ADP
hjic-1157	50	11	conversion	conversion	NOUN
hjic-1157	50	12	measurements	measurement	NOUN
hjic-1157	50	13	are	be	AUX
hjic-1157	50	14	unsuitable	unsuitable	ADJ
hjic-1157	50	15	for	for	ADP
hjic-1157	50	16	determining	determine	VERB
hjic-1157	50	17	the	the	DET
hjic-1157	50	18	masstransfer	masstransfer	NOUN
hjic-1157	50	19	rate	rate	NOUN
hjic-1157	50	20	through	through	ADP
hjic-1157	50	21	organic	organic	ADJ
hjic-1157	50	22	-	-	PUNCT
hjic-1157	50	23	water	water	NOUN
hjic-1157	50	24	interface	interface	NOUN
hjic-1157	50	25	,	,	PUNCT
hjic-1157	50	26	a	a	DET
hjic-1157	50	27	simplified	simplified	ADJ
hjic-1157	50	28	system	system	NOUN
hjic-1157	50	29	was	be	AUX
hjic-1157	50	30	applied	apply	VERB
hjic-1157	50	31	for	for	ADP
hjic-1157	50	32	this	this	DET
hjic-1157	50	33	purpose	purpose	NOUN
hjic-1157	51	1	[	[	X
hjic-1157	51	2	13	13	NUM
hjic-1157	51	3	]	]	PUNCT
hjic-1157	51	4	.	.	PUNCT
hjic-1157	52	1	13.4	13.4	NUM
hjic-1157	52	2	mg	mg	NOUN
hjic-1157	52	3	of	of	ADP
hjic-1157	52	4	2	2	NUM
hjic-1157	52	5	-	-	PUNCT
hjic-1157	52	6	phenylpropionaldehyde	phenylpropionaldehyde	NOUN
hjic-1157	52	7	and	and	CCONJ
hjic-1157	52	8	18.5	18.5	NUM
hjic-1157	52	9	mg	mg	NOUN
hjic-1157	52	10	of	of	ADP
hjic-1157	52	11	dodecane	dodecane	NOUN
hjic-1157	52	12	,	,	PUNCT
hjic-1157	52	13	which	which	PRON
hjic-1157	52	14	served	serve	VERB
hjic-1157	52	15	as	as	ADP
hjic-1157	52	16	an	an	DET
hjic-1157	52	17	internal	internal	ADJ
hjic-1157	52	18	standard	standard	NOUN
hjic-1157	52	19	for	for	ADP
hjic-1157	52	20	gas	gas	NOUN
hjic-1157	52	21	chromatography	chromatography	NOUN
hjic-1157	52	22	(	(	PUNCT
hjic-1157	52	23	gc	gc	PROPN
hjic-1157	52	24	)	)	PUNCT
hjic-1157	52	25	analysis	analysis	NOUN
hjic-1157	52	26	,	,	PUNCT
hjic-1157	52	27	were	be	AUX
hjic-1157	52	28	dissolved	dissolve	VERB
hjic-1157	52	29	in	in	ADP
hjic-1157	52	30	10	10	NUM
hjic-1157	52	31	ml	ml	NOUN
hjic-1157	52	32	of	of	ADP
hjic-1157	52	33	diisopropyl	diisopropyl	NOUN
hjic-1157	52	34	ether	ether	NOUN
hjic-1157	52	35	.	.	PUNCT
hjic-1157	53	1	a	a	DET
hjic-1157	53	2	schott	schott	ADJ
hjic-1157	53	3	glass	glass	NOUN
hjic-1157	53	4	bottle	bottle	NOUN
hjic-1157	53	5	was	be	AUX
hjic-1157	53	6	filled	fill	VERB
hjic-1157	53	7	with	with	ADP
hjic-1157	53	8	6	6	NUM
hjic-1157	53	9	l	l	NOUN
hjic-1157	53	10	of	of	ADP
hjic-1157	53	11	distilled	distil	VERB
hjic-1157	53	12	water	water	NOUN
hjic-1157	53	13	and	and	CCONJ
hjic-1157	53	14	the	the	DET
hjic-1157	53	15	organic	organic	ADJ
hjic-1157	53	16	solution	solution	NOUN
hjic-1157	53	17	carefully	carefully	ADV
hjic-1157	53	18	poured	pour	VERB
hjic-1157	53	19	onto	onto	ADP
hjic-1157	53	20	the	the	DET
hjic-1157	53	21	surface	surface	NOUN
hjic-1157	53	22	of	of	ADP
hjic-1157	53	23	the	the	DET
hjic-1157	53	24	water	water	NOUN
hjic-1157	53	25	phase	phase	NOUN
hjic-1157	53	26	.	.	PUNCT
hjic-1157	54	1	during	during	ADP
hjic-1157	54	2	the	the	DET
hjic-1157	54	3	following	follow	VERB
hjic-1157	54	4	27	27	NUM
hjic-1157	54	5	hours	hour	NOUN
hjic-1157	54	6	,	,	PUNCT
hjic-1157	54	7	samples	sample	NOUN
hjic-1157	54	8	were	be	AUX
hjic-1157	54	9	taken	take	VERB
hjic-1157	54	10	from	from	ADP
hjic-1157	54	11	the	the	DET
hjic-1157	54	12	organic	organic	ADJ
hjic-1157	54	13	phase	phase	NOUN
hjic-1157	54	14	and	and	CCONJ
hjic-1157	54	15	analysed	analyse	VERB
hjic-1157	54	16	by	by	ADP
hjic-1157	54	17	gc	gc	PROPN
hjic-1157	54	18	.	.	PUNCT
hjic-1157	55	1	(	(	PUNCT
hjic-1157	55	2	the	the	DET
hjic-1157	55	3	parameters	parameter	NOUN
hjic-1157	55	4	of	of	ADP
hjic-1157	55	5	chromatographic	chromatographic	ADJ
hjic-1157	55	6	analysis	analysis	NOUN
hjic-1157	55	7	were	be	AUX
hjic-1157	55	8	the	the	DET
hjic-1157	55	9	same	same	ADJ
hjic-1157	55	10	as	as	SCONJ
hjic-1157	55	11	described	describe	VERB
hjic-1157	55	12	in	in	ADP
hjic-1157	55	13	sec	sec	PROPN
hjic-1157	55	14	.	.	PROPN
hjic-1157	55	15	2.4	2.4	NUM
hjic-1157	55	16	)	)	PUNCT
hjic-1157	55	17	.	.	PUNCT
hjic-1157	56	1	the	the	DET
hjic-1157	56	2	ratio	ratio	NOUN
hjic-1157	56	3	of	of	ADP
hjic-1157	56	4	aldehyde	aldehyde	NOUN
hjic-1157	56	5	to	to	ADP
hjic-1157	56	6	dodecane	dodecane	NOUN
hjic-1157	56	7	was	be	AUX
hjic-1157	56	8	plotted	plot	VERB
hjic-1157	56	9	as	as	ADP
hjic-1157	56	10	a	a	DET
hjic-1157	56	11	function	function	NOUN
hjic-1157	56	12	of	of	ADP
hjic-1157	56	13	time	time	NOUN
hjic-1157	56	14	and	and	CCONJ
hjic-1157	56	15	a	a	DET
hjic-1157	56	16	kinetic	kinetic	ADJ
hjic-1157	56	17	model	model	NOUN
hjic-1157	56	18	was	be	AUX
hjic-1157	56	19	fitted	fit	VERB
hjic-1157	56	20	to	to	ADP
hjic-1157	56	21	the	the	DET
hjic-1157	56	22	measured	measured	ADJ
hjic-1157	56	23	data	datum	NOUN
hjic-1157	56	24	in	in	ADP
hjic-1157	56	25	accordance	accordance	NOUN
hjic-1157	56	26	with	with	ADP
hjic-1157	56	27	the	the	DET
hjic-1157	56	28	following	follow	VERB
hjic-1157	56	29	equation	equation	NOUN
hjic-1157	56	30	:	:	PUNCT
hjic-1157	56	31	j	j	PROPN
hjic-1157	56	32	=	=	PUNCT
hjic-1157	56	33	d(c0	d(c0	PROPN
hjic-1157	57	1	−	−	PROPN
hjic-1157	57	2	acw	acw	PROPN
hjic-1157	57	3	)	)	PUNCT
hjic-1157	57	4	(	(	PUNCT
hjic-1157	57	5	2	2	X
hjic-1157	57	6	)	)	PUNCT
hjic-1157	57	7	where	where	SCONJ
hjic-1157	57	8	j	j	PROPN
hjic-1157	57	9	denotes	denote	VERB
hjic-1157	57	10	mass	mass	NOUN
hjic-1157	57	11	transfer	transfer	NOUN
hjic-1157	57	12	through	through	ADP
hjic-1157	57	13	the	the	DET
hjic-1157	57	14	interface	interface	NOUN
hjic-1157	57	15	[	[	X
hjic-1157	57	16	mol/(min	mol/(min	PROPN
hjic-1157	57	17	cm2	cm2	PROPN
hjic-1157	57	18	)	)	PUNCT
hjic-1157	57	19	]	]	PUNCT
hjic-1157	57	20	,	,	PUNCT
hjic-1157	57	21	d	d	PRON
hjic-1157	57	22	represents	represent	VERB
hjic-1157	57	23	the	the	DET
hjic-1157	57	24	mass	mass	ADJ
hjic-1157	57	25	transfer	transfer	NOUN
hjic-1157	57	26	coefficient	coefficient	NOUN
hjic-1157	57	27	[	[	X
hjic-1157	57	28	cm	cm	NOUN
hjic-1157	57	29	/	/	SYM
hjic-1157	57	30	min	min	NOUN
hjic-1157	57	31	]	]	X
hjic-1157	57	32	,	,	PUNCT
hjic-1157	57	33	c0	c0	PROPN
hjic-1157	57	34	stands	stand	VERB
hjic-1157	57	35	for	for	ADP
hjic-1157	57	36	the	the	DET
hjic-1157	57	37	initial	initial	ADJ
hjic-1157	57	38	substrate	substrate	NOUN
hjic-1157	57	39	concentration	concentration	NOUN
hjic-1157	57	40	in	in	ADP
hjic-1157	57	41	the	the	DET
hjic-1157	57	42	organic	organic	ADJ
hjic-1157	57	43	phase	phase	NOUN
hjic-1157	57	44	[	[	X
hjic-1157	57	45	mol	mol	NOUN
hjic-1157	57	46	/	/	SYM
hjic-1157	57	47	cm3	cm3	NOUN
hjic-1157	57	48	]	]	PUNCT
hjic-1157	57	49	,	,	PUNCT
hjic-1157	57	50	cw	cw	NOUN
hjic-1157	57	51	refers	refer	VERB
hjic-1157	57	52	to	to	ADP
hjic-1157	57	53	the	the	DET
hjic-1157	57	54	substrate	substrate	NOUN
hjic-1157	57	55	concentration	concentration	NOUN
hjic-1157	57	56	in	in	ADP
hjic-1157	57	57	the	the	DET
hjic-1157	57	58	water	water	NOUN
hjic-1157	57	59	phase	phase	NOUN
hjic-1157	57	60	[	[	X
hjic-1157	57	61	mol	mol	ADP
hjic-1157	57	62	/	/	SYM
hjic-1157	57	63	cm3	cm3	NOUN
hjic-1157	57	64	]	]	PUNCT
hjic-1157	57	65	and	and	CCONJ
hjic-1157	57	66	a	a	PRON
hjic-1157	57	67	is	be	AUX
hjic-1157	57	68	the	the	DET
hjic-1157	57	69	ratio	ratio	NOUN
hjic-1157	57	70	of	of	ADP
hjic-1157	57	71	the	the	DET
hjic-1157	57	72	activity	activity	NOUN
hjic-1157	57	73	coefficients	coefficient	NOUN
hjic-1157	57	74	.	.	PUNCT
hjic-1157	58	1	the	the	DET
hjic-1157	58	2	difference	difference	NOUN
hjic-1157	58	3	between	between	ADP
hjic-1157	58	4	the	the	DET
hjic-1157	58	5	measured	measure	VERB
hjic-1157	58	6	and	and	CCONJ
hjic-1157	58	7	calculated	calculate	VERB
hjic-1157	58	8	data	datum	NOUN
hjic-1157	58	9	was	be	AUX
hjic-1157	58	10	minimized	minimize	VERB
hjic-1157	58	11	by	by	ADP
hjic-1157	58	12	the	the	DET
hjic-1157	58	13	excel	excel	PROPN
hjic-1157	58	14	solver	solver	NOUN
hjic-1157	58	15	plug	plug	NOUN
hjic-1157	58	16	-	-	PUNCT
hjic-1157	58	17	in	in	NOUN
hjic-1157	58	18	.	.	PUNCT
hjic-1157	59	1	although	although	SCONJ
hjic-1157	59	2	the	the	DET
hjic-1157	59	3	water	water	NOUN
hjic-1157	59	4	phase	phase	NOUN
hjic-1157	59	5	was	be	AUX
hjic-1157	59	6	gently	gently	ADV
hjic-1157	59	7	mixed	mix	VERB
hjic-1157	59	8	by	by	ADP
hjic-1157	59	9	a	a	DET
hjic-1157	59	10	magnetic	magnetic	ADJ
hjic-1157	59	11	stirrer	stirrer	NOUN
hjic-1157	59	12	,	,	PUNCT
hjic-1157	59	13	the	the	DET
hjic-1157	59	14	water	water	NOUN
hjic-1157	59	15	–	–	PUNCT
hjic-1157	59	16	organic	organic	ADJ
hjic-1157	59	17	interface	interface	NOUN
hjic-1157	59	18	was	be	AUX
hjic-1157	59	19	stationary	stationary	ADJ
hjic-1157	59	20	.	.	PUNCT
hjic-1157	60	1	therefore	therefore	ADV
hjic-1157	60	2	,	,	PUNCT
hjic-1157	60	3	its	its	PRON
hjic-1157	60	4	surface	surface	NOUN
hjic-1157	60	5	can	can	AUX
hjic-1157	60	6	be	be	AUX
hjic-1157	60	7	regarded	regard	VERB
hjic-1157	60	8	as	as	ADP
hjic-1157	60	9	a	a	DET
hjic-1157	60	10	constant	constant	NOUN
hjic-1157	60	11	.	.	PUNCT
hjic-1157	61	1	the	the	DET
hjic-1157	61	2	mass	mass	NOUN
hjic-1157	61	3	transfer	transfer	NOUN
hjic-1157	61	4	rate	rate	NOUN
hjic-1157	61	5	can	can	AUX
hjic-1157	61	6	be	be	AUX
hjic-1157	61	7	calculated	calculate	VERB
hjic-1157	61	8	by	by	ADP
hjic-1157	61	9	dividing	divide	VERB
hjic-1157	61	10	the	the	DET
hjic-1157	61	11	mass	mass	NOUN
hjic-1157	61	12	transfer	transfer	NOUN
hjic-1157	61	13	(	(	PUNCT
hjic-1157	61	14	j	j	NOUN
hjic-1157	61	15	)	)	PUNCT
hjic-1157	61	16	by	by	ADP
hjic-1157	61	17	the	the	DET
hjic-1157	61	18	interfacial	interfacial	ADJ
hjic-1157	61	19	area	area	NOUN
hjic-1157	61	20	.	.	PUNCT
hjic-1157	62	1	hungarian	hungarian	ADJ
hjic-1157	62	2	journal	journal	NOUN
hjic-1157	62	3	of	of	ADP
hjic-1157	62	4	industry	industry	NOUN
hjic-1157	62	5	and	and	CCONJ
hjic-1157	62	6	chemistry	chemistry	NOUN
hjic-1157	62	7	production	production	NOUN
hjic-1157	62	8	of	of	ADP
hjic-1157	62	9	chiral	chiral	ADJ
hjic-1157	62	10	(	(	PUNCT
hjic-1157	62	11	s)-2	s)-2	NOUN
hjic-1157	62	12	-	-	PUNCT
hjic-1157	62	13	phenyl-1	phenyl-1	NOUN
hjic-1157	62	14	-	-	PUNCT
hjic-1157	62	15	propanol	propanol	ADJ
hjic-1157	62	16	25	25	NUM
hjic-1157	62	17	table	table	NOUN
hjic-1157	62	18	1	1	NUM
hjic-1157	62	19	:	:	PUNCT
hjic-1157	62	20	heating	heating	NOUN
hjic-1157	62	21	program	program	NOUN
hjic-1157	62	22	ramp	ramp	NOUN
hjic-1157	62	23	rate	rate	NOUN
hjic-1157	62	24	[	[	X
hjic-1157	62	25	◦	◦	NOUN
hjic-1157	62	26	c	c	NOUN
hjic-1157	62	27	/	/	SYM
hjic-1157	62	28	min	min	NOUN
hjic-1157	62	29	]	]	X
hjic-1157	62	30	temperature	temperature	NOUN
hjic-1157	63	1	[	[	X
hjic-1157	63	2	◦	◦	NOUN
hjic-1157	63	3	c	c	X
hjic-1157	63	4	]	]	X
hjic-1157	63	5	hold	hold	VERB
hjic-1157	63	6	time	time	NOUN
hjic-1157	63	7	[	[	X
hjic-1157	63	8	min	min	X
hjic-1157	63	9	]	]	X
hjic-1157	63	10	70	70	NUM
hjic-1157	63	11	25	25	NUM
hjic-1157	63	12	1	1	NUM
hjic-1157	63	13	110	110	NUM
hjic-1157	63	14	0	0	NUM
hjic-1157	63	15	20	20	NUM
hjic-1157	63	16	180	180	NUM
hjic-1157	63	17	2	2	NUM
hjic-1157	63	18	2.4	2.4	NUM
hjic-1157	63	19	kinetics	kinetic	NOUN
hjic-1157	63	20	in	in	ADP
hjic-1157	63	21	all	all	DET
hjic-1157	63	22	the	the	DET
hjic-1157	63	23	experiments	experiment	NOUN
hjic-1157	63	24	,	,	PUNCT
hjic-1157	63	25	7	7	NUM
hjic-1157	63	26	cm3	cm3	NOUN
hjic-1157	63	27	of	of	ADP
hjic-1157	63	28	organic	organic	ADJ
hjic-1157	63	29	solvent	solvent	NOUN
hjic-1157	63	30	and	and	CCONJ
hjic-1157	63	31	7	7	NUM
hjic-1157	63	32	cm3	cm3	NOUN
hjic-1157	63	33	of	of	ADP
hjic-1157	63	34	phosphate	phosphate	ADJ
hjic-1157	63	35	buffer	buffer	NOUN
hjic-1157	63	36	(	(	PUNCT
hjic-1157	63	37	75	75	NUM
hjic-1157	63	38	mm	mm	NOUN
hjic-1157	63	39	,	,	PUNCT
hjic-1157	63	40	ph	ph	PROPN
hjic-1157	63	41	8.0	8.0	NUM
hjic-1157	63	42	)	)	PUNCT
hjic-1157	63	43	were	be	AUX
hjic-1157	63	44	used	use	VERB
hjic-1157	63	45	.	.	PUNCT
hjic-1157	64	1	the	the	DET
hjic-1157	64	2	molar	molar	ADJ
hjic-1157	64	3	ratio	ratio	NOUN
hjic-1157	64	4	of	of	ADP
hjic-1157	64	5	2	2	NUM
hjic-1157	64	6	-	-	PUNCT
hjic-1157	64	7	phenylpropionaldehyde	phenylpropionaldehyde	NOUN
hjic-1157	64	8	to	to	ADP
hjic-1157	64	9	ethyl	ethyl	PROPN
hjic-1157	64	10	alcohol	alcohol	NOUN
hjic-1157	64	11	was	be	AUX
hjic-1157	64	12	set	set	VERB
hjic-1157	64	13	at	at	ADP
hjic-1157	64	14	3.7	3.7	NUM
hjic-1157	64	15	,	,	PUNCT
hjic-1157	64	16	based	base	VERB
hjic-1157	64	17	on	on	ADP
hjic-1157	64	18	data	datum	NOUN
hjic-1157	64	19	from	from	ADP
hjic-1157	64	20	the	the	DET
hjic-1157	64	21	literature	literature	NOUN
hjic-1157	64	22	[	[	X
hjic-1157	64	23	14	14	NUM
hjic-1157	64	24	]	]	PUNCT
hjic-1157	64	25	.	.	PUNCT
hjic-1157	65	1	in	in	ADP
hjic-1157	65	2	the	the	DET
hjic-1157	65	3	case	case	NOUN
hjic-1157	65	4	of	of	ADP
hjic-1157	65	5	isolated	isolated	ADJ
hjic-1157	65	6	adh	adh	NOUN
hjic-1157	65	7	,	,	PUNCT
hjic-1157	65	8	60	60	NUM
hjic-1157	65	9	µl	µl	NOUN
hjic-1157	65	10	of	of	ADP
hjic-1157	65	11	nadh	nadh	NOUN
hjic-1157	65	12	solution	solution	NOUN
hjic-1157	65	13	(	(	PUNCT
hjic-1157	65	14	7.5	7.5	NUM
hjic-1157	65	15	mg	mg	NUM
hjic-1157	65	16	/	/	SYM
hjic-1157	65	17	ml	ml	NOUN
hjic-1157	65	18	,	,	PUNCT
hjic-1157	65	19	freshly	freshly	ADV
hjic-1157	65	20	made	make	VERB
hjic-1157	65	21	with	with	ADP
hjic-1157	65	22	a	a	DET
hjic-1157	65	23	buffer	buffer	NOUN
hjic-1157	65	24	solution	solution	NOUN
hjic-1157	65	25	)	)	PUNCT
hjic-1157	65	26	was	be	AUX
hjic-1157	65	27	added	add	VERB
hjic-1157	65	28	to	to	ADP
hjic-1157	65	29	the	the	DET
hjic-1157	65	30	reaction	reaction	NOUN
hjic-1157	65	31	media	medium	NOUN
hjic-1157	65	32	.	.	PUNCT
hjic-1157	66	1	(	(	PUNCT
hjic-1157	66	2	the	the	DET
hjic-1157	66	3	optimal	optimal	ADJ
hjic-1157	66	4	amount	amount	NOUN
hjic-1157	66	5	of	of	ADP
hjic-1157	66	6	cofactor	cofactor	NOUN
hjic-1157	66	7	was	be	AUX
hjic-1157	66	8	determined	determine	VERB
hjic-1157	66	9	during	during	ADP
hjic-1157	66	10	preliminary	preliminary	ADJ
hjic-1157	66	11	measurements	measurement	NOUN
hjic-1157	66	12	,	,	PUNCT
hjic-1157	66	13	however	however	ADV
hjic-1157	66	14	,	,	PUNCT
hjic-1157	66	15	this	this	DET
hjic-1157	66	16	data	data	NOUN
hjic-1157	66	17	is	be	AUX
hjic-1157	66	18	not	not	PART
hjic-1157	66	19	shown	show	VERB
hjic-1157	66	20	.	.	PUNCT
hjic-1157	66	21	)	)	PUNCT
hjic-1157	67	1	in	in	ADP
hjic-1157	67	2	the	the	DET
hjic-1157	67	3	case	case	NOUN
hjic-1157	67	4	of	of	ADP
hjic-1157	67	5	instant	instant	NOUN
hjic-1157	67	6	baker	baker	NOUN
hjic-1157	67	7	’s	’s	PART
hjic-1157	67	8	dry	dry	ADJ
hjic-1157	67	9	yeast	yeast	NOUN
hjic-1157	67	10	,	,	PUNCT
hjic-1157	67	11	since	since	SCONJ
hjic-1157	67	12	the	the	DET
hjic-1157	67	13	cell	cell	NOUN
hjic-1157	67	14	contained	contain	VERB
hjic-1157	67	15	a	a	DET
hjic-1157	67	16	sufficient	sufficient	ADJ
hjic-1157	67	17	amount	amount	NOUN
hjic-1157	67	18	of	of	ADP
hjic-1157	67	19	cofactor	cofactor	NOUN
hjic-1157	67	20	,	,	PUNCT
hjic-1157	67	21	no	no	DET
hjic-1157	67	22	further	further	ADJ
hjic-1157	67	23	addition	addition	NOUN
hjic-1157	67	24	of	of	ADP
hjic-1157	67	25	nadh	nadh	NOUN
hjic-1157	67	26	was	be	AUX
hjic-1157	67	27	necessary	necessary	ADJ
hjic-1157	67	28	.	.	PUNCT
hjic-1157	68	1	the	the	DET
hjic-1157	68	2	reactions	reaction	NOUN
hjic-1157	68	3	were	be	AUX
hjic-1157	68	4	initiated	initiate	VERB
hjic-1157	68	5	by	by	ADP
hjic-1157	68	6	adding	add	VERB
hjic-1157	68	7	the	the	DET
hjic-1157	68	8	catalyst	catalyst	NOUN
hjic-1157	68	9	–	–	PUNCT
hjic-1157	68	10	300	300	NUM
hjic-1157	68	11	mg	mg	NOUN
hjic-1157	68	12	of	of	ADP
hjic-1157	68	13	instant	instant	NOUN
hjic-1157	68	14	baker	baker	NOUN
hjic-1157	68	15	’s	’s	PART
hjic-1157	68	16	dry	dry	ADJ
hjic-1157	68	17	yeast	yeast	NOUN
hjic-1157	68	18	or	or	CCONJ
hjic-1157	68	19	500	500	NUM
hjic-1157	68	20	µl	µl	NOUN
hjic-1157	68	21	of	of	ADP
hjic-1157	68	22	enzyme	enzyme	NOUN
hjic-1157	68	23	solution	solution	NOUN
hjic-1157	68	24	(	(	PUNCT
hjic-1157	68	25	10	10	NUM
hjic-1157	68	26	mg	mg	NUM
hjic-1157	68	27	/	/	SYM
hjic-1157	68	28	ml	ml	NOUN
hjic-1157	68	29	,	,	PUNCT
hjic-1157	68	30	freshly	freshly	ADV
hjic-1157	68	31	made	make	VERB
hjic-1157	68	32	with	with	ADP
hjic-1157	68	33	a	a	DET
hjic-1157	68	34	buffer	buffer	NOUN
hjic-1157	68	35	solution	solution	NOUN
hjic-1157	68	36	)	)	PUNCT
hjic-1157	68	37	.	.	PUNCT
hjic-1157	69	1	the	the	DET
hjic-1157	69	2	reaction	reaction	NOUN
hjic-1157	69	3	mixtures	mixture	NOUN
hjic-1157	69	4	were	be	AUX
hjic-1157	69	5	shaken	shake	VERB
hjic-1157	69	6	in	in	ADP
hjic-1157	69	7	a	a	DET
hjic-1157	69	8	thermostatic	thermostatic	ADJ
hjic-1157	69	9	incubator	incubator	NOUN
hjic-1157	69	10	(	(	PUNCT
hjic-1157	69	11	ika	ika	X
hjic-1157	69	12	ks	ks	NOUN
hjic-1157	69	13	4000	4000	NUM
hjic-1157	69	14	i	i	PRON
hjic-1157	69	15	control	control	VERB
hjic-1157	69	16	)	)	PUNCT
hjic-1157	69	17	at	at	ADP
hjic-1157	69	18	200	200	NUM
hjic-1157	69	19	rpm	rpm	NOUN
hjic-1157	69	20	and	and	CCONJ
hjic-1157	69	21	30	30	NUM
hjic-1157	69	22	◦	◦	NOUN
hjic-1157	69	23	c.	c.	NOUN
hjic-1157	69	24	to	to	PART
hjic-1157	69	25	investigate	investigate	VERB
hjic-1157	69	26	the	the	DET
hjic-1157	69	27	product	product	NOUN
hjic-1157	69	28	formation	formation	NOUN
hjic-1157	69	29	,	,	PUNCT
hjic-1157	69	30	samples	sample	NOUN
hjic-1157	69	31	were	be	AUX
hjic-1157	69	32	taken	take	VERB
hjic-1157	69	33	from	from	ADP
hjic-1157	69	34	the	the	DET
hjic-1157	69	35	organic	organic	ADJ
hjic-1157	69	36	phase	phase	NOUN
hjic-1157	69	37	and	and	CCONJ
hjic-1157	69	38	analysed	analyse	VERB
hjic-1157	69	39	by	by	ADP
hjic-1157	69	40	an	an	DET
hjic-1157	69	41	hp	hp	ADJ
hjic-1157	69	42	5890	5890	NUM
hjic-1157	69	43	gas	gas	NOUN
hjic-1157	69	44	chromatograph	chromatograph	NOUN
hjic-1157	69	45	(	(	PUNCT
hjic-1157	69	46	140	140	NUM
hjic-1157	69	47	◦	◦	NOUN
hjic-1157	69	48	c	c	NOUN
hjic-1157	69	49	isothermal	isothermal	NOUN
hjic-1157	69	50	)	)	PUNCT
hjic-1157	69	51	.	.	PUNCT
hjic-1157	70	1	the	the	DET
hjic-1157	70	2	gc	gc	PROPN
hjic-1157	70	3	was	be	AUX
hjic-1157	70	4	equipped	equip	VERB
hjic-1157	70	5	with	with	ADP
hjic-1157	70	6	a	a	DET
hjic-1157	70	7	db	db	ADJ
hjic-1157	70	8	-	-	PUNCT
hjic-1157	70	9	ffap	ffap	ADJ
hjic-1157	70	10	column	column	NOUN
hjic-1157	70	11	(	(	PUNCT
hjic-1157	70	12	1	1	NUM
hjic-1157	70	13	µm	µm	ADP
hjic-1157	70	14	×	×	NOUN
hjic-1157	70	15	30	30	NUM
hjic-1157	70	16	m	m	NOUN
hjic-1157	70	17	×	×	NOUN
hjic-1157	70	18	0.53	0.53	NUM
hjic-1157	70	19	mm	mm	PROPN
hjic-1157	70	20	,	,	PUNCT
hjic-1157	70	21	agilent	agilent	PROPN
hjic-1157	70	22	technologies	technologies	PROPN
hjic-1157	70	23	)	)	PUNCT
hjic-1157	70	24	and	and	CCONJ
hjic-1157	70	25	a	a	DET
hjic-1157	70	26	flame	flame	NOUN
hjic-1157	70	27	ionisation	ionisation	NOUN
hjic-1157	70	28	detector	detector	NOUN
hjic-1157	70	29	.	.	PUNCT
hjic-1157	71	1	2.5	2.5	NUM
hjic-1157	71	2	enantioselectivity	enantioselectivity	NOUN
hjic-1157	71	3	while	while	SCONJ
hjic-1157	71	4	measuring	measure	VERB
hjic-1157	71	5	the	the	DET
hjic-1157	71	6	enantioselectivity	enantioselectivity	NOUN
hjic-1157	71	7	,	,	PUNCT
hjic-1157	71	8	the	the	DET
hjic-1157	71	9	content	content	NOUN
hjic-1157	71	10	of	of	ADP
hjic-1157	71	11	the	the	DET
hjic-1157	71	12	reaction	reaction	NOUN
hjic-1157	71	13	mixture	mixture	NOUN
hjic-1157	71	14	and	and	CCONJ
hjic-1157	71	15	operational	operational	ADJ
hjic-1157	71	16	parameters	parameter	NOUN
hjic-1157	71	17	were	be	AUX
hjic-1157	71	18	the	the	DET
hjic-1157	71	19	same	same	ADJ
hjic-1157	71	20	as	as	SCONJ
hjic-1157	71	21	described	describe	VERB
hjic-1157	71	22	in	in	ADP
hjic-1157	71	23	sec	sec	PROPN
hjic-1157	71	24	.	.	PROPN
hjic-1157	72	1	2.3	2.3	NUM
hjic-1157	72	2	.	.	PUNCT
hjic-1157	73	1	before	before	ADP
hjic-1157	73	2	gc	gc	PROPN
hjic-1157	73	3	analysis	analysis	NOUN
hjic-1157	73	4	,	,	PUNCT
hjic-1157	73	5	preliminary	preliminary	ADJ
hjic-1157	73	6	derivatization	derivatization	NOUN
hjic-1157	73	7	was	be	AUX
hjic-1157	73	8	required	require	VERB
hjic-1157	73	9	.	.	PUNCT
hjic-1157	74	1	1	1	NUM
hjic-1157	74	2	ml	ml	NOUN
hjic-1157	74	3	of	of	ADP
hjic-1157	74	4	trifluoroacetic	trifluoroacetic	ADJ
hjic-1157	74	5	anhydride	anhydride	NOUN
hjic-1157	74	6	and	and	CCONJ
hjic-1157	74	7	1	1	NUM
hjic-1157	74	8	ml	ml	NOUN
hjic-1157	74	9	of	of	ADP
hjic-1157	74	10	diisopropyl	diisopropyl	NOUN
hjic-1157	74	11	ether	ether	NOUN
hjic-1157	74	12	were	be	AUX
hjic-1157	74	13	added	add	VERB
hjic-1157	74	14	to	to	ADP
hjic-1157	74	15	500	500	NUM
hjic-1157	74	16	µl	µl	NOUN
hjic-1157	74	17	of	of	ADP
hjic-1157	74	18	the	the	DET
hjic-1157	74	19	sample	sample	NOUN
hjic-1157	74	20	while	while	SCONJ
hjic-1157	74	21	heating	heat	VERB
hjic-1157	74	22	the	the	DET
hjic-1157	74	23	mixture	mixture	NOUN
hjic-1157	74	24	under	under	ADP
hjic-1157	74	25	reflux	reflux	NOUN
hjic-1157	74	26	at	at	ADP
hjic-1157	74	27	70	70	NUM
hjic-1157	74	28	◦	◦	NOUN
hjic-1157	74	29	c	c	NOUN
hjic-1157	74	30	for	for	ADP
hjic-1157	74	31	30	30	NUM
hjic-1157	74	32	mins	min	NOUN
hjic-1157	74	33	.	.	PUNCT
hjic-1157	75	1	once	once	SCONJ
hjic-1157	75	2	the	the	DET
hjic-1157	75	3	reaction	reaction	NOUN
hjic-1157	75	4	mixture	mixture	NOUN
hjic-1157	75	5	had	have	AUX
hjic-1157	75	6	been	be	AUX
hjic-1157	75	7	cooled	cool	VERB
hjic-1157	75	8	to	to	ADP
hjic-1157	75	9	room	room	NOUN
hjic-1157	75	10	temperature	temperature	NOUN
hjic-1157	75	11	,	,	PUNCT
hjic-1157	75	12	it	it	PRON
hjic-1157	75	13	was	be	AUX
hjic-1157	75	14	neutralized	neutralize	VERB
hjic-1157	75	15	with	with	ADP
hjic-1157	75	16	4	4	NUM
hjic-1157	75	17	ml	ml	NOUN
hjic-1157	75	18	of	of	ADP
hjic-1157	75	19	na2co3	na2co3	NOUN
hjic-1157	75	20	(	(	PUNCT
hjic-1157	75	21	20	20	NUM
hjic-1157	75	22	%	%	NOUN
hjic-1157	75	23	)	)	PUNCT
hjic-1157	75	24	and	and	CCONJ
hjic-1157	75	25	a	a	DET
hjic-1157	75	26	sample	sample	NOUN
hjic-1157	75	27	from	from	ADP
hjic-1157	75	28	the	the	DET
hjic-1157	75	29	organic	organic	ADJ
hjic-1157	75	30	phase	phase	NOUN
hjic-1157	75	31	analysed	analyse	VERB
hjic-1157	75	32	by	by	ADP
hjic-1157	75	33	a	a	DET
hjic-1157	75	34	shimadzu	shimadzu	ADJ
hjic-1157	75	35	gc-2014	gc-2014	NOUN
hjic-1157	75	36	gas	gas	NOUN
hjic-1157	75	37	chromatograph	chromatograph	NOUN
hjic-1157	75	38	equipped	equip	VERB
hjic-1157	75	39	with	with	ADP
hjic-1157	75	40	a	a	DET
hjic-1157	75	41	lipodex	lipodex	NOUN
hjic-1157	75	42	e	e	NOUN
hjic-1157	75	43	capillary	capillary	ADJ
hjic-1157	75	44	column	column	NOUN
hjic-1157	75	45	(	(	PUNCT
hjic-1157	75	46	0.2	0.2	NUM
hjic-1157	75	47	µm	µm	SYM
hjic-1157	75	48	×	×	NOUN
hjic-1157	75	49	25	25	NUM
hjic-1157	75	50	m	m	NOUN
hjic-1157	75	51	×	×	NOUN
hjic-1157	75	52	0.25	0.25	NUM
hjic-1157	75	53	mm	mm	NOUN
hjic-1157	75	54	,	,	PUNCT
hjic-1157	75	55	macherey	macherey	PROPN
hjic-1157	75	56	-	-	PUNCT
hjic-1157	75	57	nagel	nagel	PROPN
hjic-1157	75	58	)	)	PUNCT
hjic-1157	75	59	and	and	CCONJ
hjic-1157	75	60	a	a	DET
hjic-1157	75	61	flame	flame	NOUN
hjic-1157	75	62	ionisation	ionisation	NOUN
hjic-1157	75	63	detector	detector	NOUN
hjic-1157	75	64	.	.	PUNCT
hjic-1157	76	1	table	table	NOUN
hjic-1157	76	2	1	1	NUM
hjic-1157	76	3	contains	contain	VERB
hjic-1157	76	4	the	the	DET
hjic-1157	76	5	parameters	parameter	NOUN
hjic-1157	76	6	of	of	ADP
hjic-1157	76	7	the	the	DET
hjic-1157	76	8	applied	apply	VERB
hjic-1157	76	9	heating	heating	NOUN
hjic-1157	76	10	program	program	NOUN
hjic-1157	76	11	.	.	PUNCT
hjic-1157	77	1	the	the	DET
hjic-1157	77	2	peaks	peak	NOUN
hjic-1157	77	3	were	be	AUX
hjic-1157	77	4	deconvoluted	deconvolute	VERB
hjic-1157	77	5	by	by	ADP
hjic-1157	77	6	originpro	originpro	ADJ
hjic-1157	77	7	software	software	NOUN
hjic-1157	77	8	to	to	PART
hjic-1157	77	9	fit	fit	VERB
hjic-1157	77	10	the	the	DET
hjic-1157	77	11	gaussian	gaussian	ADJ
hjic-1157	77	12	curves	curve	NOUN
hjic-1157	77	13	.	.	PUNCT
hjic-1157	78	1	to	to	PART
hjic-1157	78	2	identify	identify	VERB
hjic-1157	78	3	the	the	DET
hjic-1157	78	4	peaks	peak	NOUN
hjic-1157	78	5	of	of	ADP
hjic-1157	78	6	the	the	DET
hjic-1157	78	7	enantiomers	enantiomer	NOUN
hjic-1157	78	8	,	,	PUNCT
hjic-1157	78	9	derivatization	derivatization	NOUN
hjic-1157	78	10	and	and	CCONJ
hjic-1157	78	11	analysis	analysis	NOUN
hjic-1157	78	12	was	be	AUX
hjic-1157	78	13	performed	perform	VERB
hjic-1157	78	14	using	use	VERB
hjic-1157	78	15	pure	pure	ADJ
hjic-1157	78	16	s-(2)-phenyl-1	s-(2)-phenyl-1	NOUN
hjic-1157	78	17	-	-	PUNCT
hjic-1157	78	18	propanol	propanol	NOUN
hjic-1157	78	19	.	.	PUNCT
hjic-1157	79	1	the	the	DET
hjic-1157	79	2	retention	retention	NOUN
hjic-1157	79	3	time	time	NOUN
hjic-1157	79	4	of	of	ADP
hjic-1157	79	5	the	the	DET
hjic-1157	79	6	derivative	derivative	NOUN
hjic-1157	79	7	of	of	ADP
hjic-1157	79	8	the	the	DET
hjic-1157	79	9	product	product	NOUN
hjic-1157	79	10	was	be	AUX
hjic-1157	79	11	52.5	52.5	NUM
hjic-1157	79	12	mins	min	NOUN
hjic-1157	79	13	.	.	PUNCT
hjic-1157	80	1	3	3	X
hjic-1157	80	2	.	.	NOUN
hjic-1157	80	3	results	result	NOUN
hjic-1157	80	4	and	and	CCONJ
hjic-1157	80	5	evaluation	evaluation	NOUN
hjic-1157	80	6	3.1	3.1	NUM
hjic-1157	80	7	kinetics	kinetic	NOUN
hjic-1157	80	8	by	by	ADP
hjic-1157	80	9	plotting	plot	VERB
hjic-1157	80	10	the	the	DET
hjic-1157	80	11	amount	amount	NOUN
hjic-1157	80	12	of	of	ADP
hjic-1157	80	13	product	product	NOUN
hjic-1157	80	14	as	as	ADP
hjic-1157	80	15	a	a	DET
hjic-1157	80	16	function	function	NOUN
hjic-1157	80	17	of	of	ADP
hjic-1157	80	18	time	time	NOUN
hjic-1157	80	19	,	,	PUNCT
hjic-1157	80	20	a	a	DET
hjic-1157	80	21	line	line	NOUN
hjic-1157	80	22	can	can	AUX
hjic-1157	80	23	be	be	AUX
hjic-1157	80	24	fitted	fit	VERB
hjic-1157	80	25	to	to	ADP
hjic-1157	80	26	the	the	DET
hjic-1157	80	27	initial	initial	ADJ
hjic-1157	80	28	linear	linear	ADJ
hjic-1157	80	29	phase	phase	NOUN
hjic-1157	80	30	of	of	ADP
hjic-1157	80	31	the	the	DET
hjic-1157	80	32	graph	graph	NOUN
hjic-1157	80	33	and	and	CCONJ
hjic-1157	80	34	its	its	PRON
hjic-1157	80	35	gradient	gradient	NOUN
hjic-1157	80	36	is	be	AUX
hjic-1157	80	37	the	the	DET
hjic-1157	80	38	initial	initial	ADJ
hjic-1157	80	39	rate	rate	NOUN
hjic-1157	80	40	of	of	ADP
hjic-1157	80	41	reaction	reaction	NOUN
hjic-1157	80	42	as	as	ADP
hjic-1157	80	43	a	a	DET
hjic-1157	80	44	result	result	NOUN
hjic-1157	80	45	of	of	ADP
hjic-1157	80	46	the	the	DET
hjic-1157	80	47	given	give	VERB
hjic-1157	80	48	substrate	substrate	NOUN
hjic-1157	80	49	concentration	concentration	NOUN
hjic-1157	80	50	.	.	PUNCT
hjic-1157	81	1	a	a	DET
hjic-1157	81	2	kinetic	kinetic	ADJ
hjic-1157	81	3	curve	curve	NOUN
hjic-1157	81	4	results	result	NOUN
hjic-1157	81	5	from	from	ADP
hjic-1157	81	6	repeating	repeat	VERB
hjic-1157	81	7	the	the	DET
hjic-1157	81	8	method	method	NOUN
hjic-1157	81	9	with	with	ADP
hjic-1157	81	10	different	different	ADJ
hjic-1157	81	11	initial	initial	ADJ
hjic-1157	81	12	substrate	substrate	NOUN
hjic-1157	81	13	concentrations	concentration	NOUN
hjic-1157	81	14	,	,	PUNCT
hjic-1157	81	15	yielding	yield	VERB
hjic-1157	81	16	information	information	NOUN
hjic-1157	81	17	about	about	ADP
hjic-1157	81	18	the	the	DET
hjic-1157	81	19	dependence	dependence	NOUN
hjic-1157	81	20	of	of	ADP
hjic-1157	81	21	the	the	DET
hjic-1157	81	22	reaction	reaction	NOUN
hjic-1157	81	23	rate	rate	NOUN
hjic-1157	81	24	on	on	ADP
hjic-1157	81	25	it	it	PRON
hjic-1157	81	26	.	.	PUNCT
hjic-1157	82	1	in	in	ADP
hjic-1157	82	2	the	the	DET
hjic-1157	82	3	case	case	NOUN
hjic-1157	82	4	of	of	ADP
hjic-1157	82	5	whole	whole	ADJ
hjic-1157	82	6	-	-	PUNCT
hjic-1157	82	7	cell	cell	NOUN
hjic-1157	82	8	biocatalysts	biocatalyst	NOUN
hjic-1157	82	9	,	,	PUNCT
hjic-1157	82	10	the	the	DET
hjic-1157	82	11	product	product	NOUN
hjic-1157	82	12	formation	formation	NOUN
hjic-1157	82	13	can	can	AUX
hjic-1157	82	14	be	be	AUX
hjic-1157	82	15	described	describe	VERB
hjic-1157	82	16	by	by	ADP
hjic-1157	82	17	the	the	DET
hjic-1157	82	18	single	single	ADJ
hjic-1157	82	19	-	-	PUNCT
hjic-1157	82	20	substrate	substrate	NOUN
hjic-1157	82	21	michaelis	michaeli	NOUN
hjic-1157	82	22	-	-	PUNCT
hjic-1157	82	23	menten	menten	ADJ
hjic-1157	82	24	model	model	NOUN
hjic-1157	82	25	as	as	SCONJ
hjic-1157	82	26	the	the	DET
hjic-1157	82	27	amount	amount	NOUN
hjic-1157	82	28	of	of	ADP
hjic-1157	82	29	cofactor	cofactor	NOUN
hjic-1157	82	30	can	can	AUX
hjic-1157	82	31	be	be	AUX
hjic-1157	82	32	considered	consider	VERB
hjic-1157	82	33	to	to	PART
hjic-1157	82	34	be	be	AUX
hjic-1157	82	35	constant	constant	ADJ
hjic-1157	82	36	due	due	ADP
hjic-1157	82	37	to	to	ADP
hjic-1157	82	38	its	its	PRON
hjic-1157	82	39	fast	fast	ADJ
hjic-1157	82	40	regeneration	regeneration	NOUN
hjic-1157	82	41	(	(	PUNCT
hjic-1157	82	42	see	see	VERB
hjic-1157	82	43	sec	sec	PROPN
hjic-1157	82	44	.	.	PROPN
hjic-1157	82	45	2.3	2.3	NUM
hjic-1157	82	46	)	)	PUNCT
hjic-1157	82	47	.	.	PUNCT
hjic-1157	83	1	in	in	ADP
hjic-1157	83	2	the	the	DET
hjic-1157	83	3	region	region	NOUN
hjic-1157	83	4	of	of	ADP
hjic-1157	83	5	lower	low	ADJ
hjic-1157	83	6	substrate	substrate	NOUN
hjic-1157	83	7	concentrations	concentration	NOUN
hjic-1157	83	8	,	,	PUNCT
hjic-1157	83	9	firstorder	firstorder	NOUN
hjic-1157	83	10	kinetics	kinetic	NOUN
hjic-1157	83	11	was	be	AUX
hjic-1157	83	12	observed	observe	VERB
hjic-1157	83	13	as	as	SCONJ
hjic-1157	83	14	expected	expect	VERB
hjic-1157	83	15	(	(	PUNCT
hjic-1157	83	16	fig	fig	NOUN
hjic-1157	83	17	.	.	PUNCT
hjic-1157	84	1	2	2	NUM
hjic-1157	84	2	)	)	PUNCT
hjic-1157	84	3	.	.	PUNCT
hjic-1157	85	1	however	however	ADV
hjic-1157	85	2	,	,	PUNCT
hjic-1157	85	3	at	at	ADP
hjic-1157	85	4	0.267	0.267	NUM
hjic-1157	85	5	m	m	NOUN
hjic-1157	85	6	,	,	PUNCT
hjic-1157	85	7	the	the	DET
hjic-1157	85	8	curve	curve	NOUN
hjic-1157	85	9	peaked	peak	VERB
hjic-1157	85	10	followed	follow	VERB
hjic-1157	85	11	by	by	ADP
hjic-1157	85	12	a	a	DET
hjic-1157	85	13	relatively	relatively	ADV
hjic-1157	85	14	steady	steady	ADJ
hjic-1157	85	15	decrease	decrease	NOUN
hjic-1157	85	16	instead	instead	ADV
hjic-1157	85	17	of	of	ADP
hjic-1157	85	18	phase	phase	NOUN
hjic-1157	85	19	saturation	saturation	NOUN
hjic-1157	85	20	.	.	PUNCT
hjic-1157	86	1	as	as	ADP
hjic-1157	86	2	a	a	DET
hjic-1157	86	3	result	result	NOUN
hjic-1157	86	4	,	,	PUNCT
hjic-1157	86	5	it	it	PRON
hjic-1157	86	6	can	can	AUX
hjic-1157	86	7	be	be	AUX
hjic-1157	86	8	concluded	conclude	VERB
hjic-1157	86	9	that	that	SCONJ
hjic-1157	86	10	higher	high	ADJ
hjic-1157	86	11	amounts	amount	NOUN
hjic-1157	86	12	of	of	ADP
hjic-1157	86	13	substrate	substrate	NOUN
hjic-1157	86	14	limit	limit	NOUN
hjic-1157	86	15	enzymatic	enzymatic	ADJ
hjic-1157	86	16	conversion	conversion	NOUN
hjic-1157	86	17	,	,	PUNCT
hjic-1157	86	18	therefore	therefore	ADV
hjic-1157	86	19	,	,	PUNCT
hjic-1157	86	20	0.267	0.267	NUM
hjic-1157	86	21	m	m	NOUN
hjic-1157	86	22	is	be	AUX
hjic-1157	86	23	the	the	DET
hjic-1157	86	24	optimal	optimal	ADJ
hjic-1157	86	25	initial	initial	ADJ
hjic-1157	86	26	concentration	concentration	NOUN
hjic-1157	86	27	to	to	PART
hjic-1157	86	28	maximise	maximise	VERB
hjic-1157	86	29	the	the	DET
hjic-1157	86	30	reaction	reaction	NOUN
hjic-1157	86	31	rate	rate	NOUN
hjic-1157	86	32	.	.	PUNCT
hjic-1157	87	1	in	in	ADP
hjic-1157	87	2	contrast	contrast	NOUN
hjic-1157	87	3	to	to	ADP
hjic-1157	87	4	yeast	yeast	NOUN
hjic-1157	87	5	cells	cell	NOUN
hjic-1157	87	6	,	,	PUNCT
hjic-1157	87	7	by	by	ADP
hjic-1157	87	8	applying	apply	VERB
hjic-1157	87	9	recombinant	recombinant	ADJ
hjic-1157	87	10	adh	adh	NOUN
hjic-1157	87	11	,	,	PUNCT
hjic-1157	87	12	the	the	DET
hjic-1157	87	13	reaction	reaction	NOUN
hjic-1157	87	14	rate	rate	NOUN
hjic-1157	87	15	of	of	ADP
hjic-1157	87	16	cofactor	cofactor	NOUN
hjic-1157	87	17	regeneration	regeneration	NOUN
hjic-1157	87	18	may	may	AUX
hjic-1157	87	19	limit	limit	VERB
hjic-1157	87	20	product	product	NOUN
hjic-1157	87	21	formation	formation	NOUN
hjic-1157	87	22	(	(	PUNCT
hjic-1157	87	23	see	see	VERB
hjic-1157	87	24	section	section	NOUN
hjic-1157	87	25	3.2	3.2	NUM
hjic-1157	87	26	)	)	PUNCT
hjic-1157	87	27	,	,	PUNCT
hjic-1157	87	28	therefore	therefore	ADV
hjic-1157	87	29	,	,	PUNCT
hjic-1157	87	30	can	can	AUX
hjic-1157	87	31	not	not	PART
hjic-1157	87	32	be	be	AUX
hjic-1157	87	33	neglected	neglect	VERB
hjic-1157	87	34	.	.	PUNCT
hjic-1157	88	1	since	since	SCONJ
hjic-1157	88	2	two	two	NUM
hjic-1157	88	3	reactions	reaction	NOUN
hjic-1157	88	4	involved	involve	VERB
hjic-1157	88	5	multiple	multiple	ADJ
hjic-1157	88	6	substrates	substrate	NOUN
hjic-1157	88	7	catalysed	catalyse	VERB
hjic-1157	88	8	simultaneously	simultaneously	ADV
hjic-1157	88	9	by	by	ADP
hjic-1157	88	10	the	the	DET
hjic-1157	88	11	same	same	ADJ
hjic-1157	88	12	enzyme	enzyme	NOUN
hjic-1157	88	13	,	,	PUNCT
hjic-1157	88	14	the	the	DET
hjic-1157	88	15	kinetics	kinetic	NOUN
hjic-1157	88	16	did	do	AUX
hjic-1157	88	17	not	not	PART
hjic-1157	88	18	follow	follow	VERB
hjic-1157	88	19	the	the	DET
hjic-1157	88	20	michaelis	michaeli	NOUN
hjic-1157	88	21	-	-	PUNCT
hjic-1157	88	22	menten	menten	ADJ
hjic-1157	88	23	model	model	NOUN
hjic-1157	88	24	.	.	PUNCT
hjic-1157	89	1	alternatively	alternatively	ADV
hjic-1157	89	2	,	,	PUNCT
hjic-1157	89	3	a	a	DET
hjic-1157	89	4	biphasic	biphasic	ADJ
hjic-1157	89	5	model	model	NOUN
hjic-1157	89	6	was	be	AUX
hjic-1157	89	7	applied	apply	VERB
hjic-1157	89	8	which	which	PRON
hjic-1157	89	9	divides	divide	VERB
hjic-1157	89	10	the	the	DET
hjic-1157	89	11	curve	curve	NOUN
hjic-1157	89	12	into	into	ADP
hjic-1157	89	13	two	two	NUM
hjic-1157	89	14	phases	phase	NOUN
hjic-1157	89	15	:	:	PUNCT
hjic-1157	89	16	at	at	ADP
hjic-1157	89	17	low	low	ADJ
hjic-1157	89	18	substrate	substrate	NOUN
hjic-1157	89	19	concentrations	concentration	NOUN
hjic-1157	89	20	,	,	PUNCT
hjic-1157	89	21	the	the	DET
hjic-1157	89	22	enzyme	enzyme	NOUN
hjic-1157	89	23	’s	’s	PART
hjic-1157	89	24	affinity	affinity	NOUN
hjic-1157	89	25	is	be	AUX
hjic-1157	89	26	relatively	relatively	ADV
hjic-1157	89	27	high	high	ADJ
hjic-1157	89	28	while	while	SCONJ
hjic-1157	89	29	the	the	DET
hjic-1157	89	30	turnover	turnover	NOUN
hjic-1157	89	31	number	number	NOUN
hjic-1157	89	32	is	be	AUX
hjic-1157	89	33	low	low	ADJ
hjic-1157	89	34	.	.	PUNCT
hjic-1157	90	1	on	on	ADP
hjic-1157	90	2	the	the	DET
hjic-1157	90	3	contrary	contrary	NOUN
hjic-1157	90	4	,	,	PUNCT
hjic-1157	90	5	a	a	DET
hjic-1157	90	6	low	low	ADJ
hjic-1157	90	7	affinity	affinity	NOUN
hjic-1157	90	8	and	and	CCONJ
hjic-1157	90	9	high	high	ADJ
hjic-1157	90	10	turnover	turnover	NOUN
hjic-1157	90	11	number	number	NOUN
hjic-1157	90	12	is	be	AUX
hjic-1157	90	13	characteristic	characteristic	ADJ
hjic-1157	90	14	of	of	ADP
hjic-1157	90	15	the	the	DET
hjic-1157	90	16	region	region	NOUN
hjic-1157	90	17	of	of	ADP
hjic-1157	90	18	high	high	ADJ
hjic-1157	90	19	substrate	substrate	NOUN
hjic-1157	90	20	concentration	concentration	NOUN
hjic-1157	90	21	(	(	PUNCT
hjic-1157	90	22	fig	fig	NOUN
hjic-1157	90	23	.	.	PUNCT
hjic-1157	91	1	3	3	NUM
hjic-1157	91	2	)	)	PUNCT
hjic-1157	91	3	.	.	PUNCT
hjic-1157	92	1	biphasic	biphasic	ADJ
hjic-1157	92	2	kinetics	kinetic	NOUN
hjic-1157	92	3	can	can	AUX
hjic-1157	92	4	be	be	AUX
hjic-1157	92	5	modelled	model	VERB
hjic-1157	92	6	by	by	ADP
hjic-1157	92	7	the	the	DET
hjic-1157	92	8	following	follow	VERB
hjic-1157	92	9	equation	equation	NOUN
hjic-1157	92	10	[	[	X
hjic-1157	92	11	15	15	NUM
hjic-1157	92	12	]	]	SYM
hjic-1157	92	13	:	:	PUNCT
hjic-1157	92	14	v	v	X
hjic-1157	92	15	=	=	PUNCT
hjic-1157	92	16	vmax1	vmax1	NOUN
hjic-1157	93	1	[	[	X
hjic-1157	93	2	s	s	X
hjic-1157	93	3	]	]	X
hjic-1157	93	4	+	+	CCONJ
hjic-1157	93	5	clint[s	clint[	NOUN
hjic-1157	93	6	]	]	X
hjic-1157	93	7	2	2	NUM
hjic-1157	93	8	km1	km1	NOUN
hjic-1157	93	9	+	+	CCONJ
hjic-1157	94	1	[	[	X
hjic-1157	94	2	s	s	X
hjic-1157	94	3	]	]	X
hjic-1157	94	4	(	(	PUNCT
hjic-1157	94	5	3	3	X
hjic-1157	94	6	)	)	PUNCT
hjic-1157	94	7	where	where	SCONJ
hjic-1157	94	8	vmax1	vmax1	NOUN
hjic-1157	94	9	as	as	ADV
hjic-1157	94	10	well	well	ADV
hjic-1157	94	11	as	as	ADP
hjic-1157	94	12	km1	km1	PROPN
hjic-1157	94	13	describe	describe	VERB
hjic-1157	94	14	the	the	DET
hjic-1157	94	15	first	first	ADJ
hjic-1157	94	16	high	high	ADJ
hjic-1157	94	17	affinity	affinity	NOUN
hjic-1157	94	18	–	–	PUNCT
hjic-1157	94	19	low	low	ADJ
hjic-1157	94	20	-	-	PUNCT
hjic-1157	94	21	turnover	turnover	NOUN
hjic-1157	94	22	phase	phase	NOUN
hjic-1157	94	23	and	and	CCONJ
hjic-1157	94	24	clint	clint	NOUN
hjic-1157	94	25	–	–	PUNCT
hjic-1157	94	26	equal	equal	ADJ
hjic-1157	94	27	to	to	ADP
hjic-1157	94	28	the	the	DET
hjic-1157	94	29	ratio	ratio	NOUN
hjic-1157	94	30	vmax2	vmax2	NOUN
hjic-1157	94	31	:	:	PUNCT
hjic-1157	94	32	km2	km2	PROPN
hjic-1157	94	33	–	–	PUNCT
hjic-1157	94	34	denotes	denote	VERB
hjic-1157	94	35	the	the	DET
hjic-1157	94	36	second	second	ADJ
hjic-1157	94	37	low	low	ADJ
hjic-1157	94	38	-	-	PUNCT
hjic-1157	94	39	affinity	affinity	NOUN
hjic-1157	94	40	–	–	PUNCT
hjic-1157	94	41	highturnover	highturnover	NOUN
hjic-1157	94	42	phase	phase	NOUN
hjic-1157	94	43	.	.	PUNCT
hjic-1157	95	1	figure	figure	NOUN
hjic-1157	95	2	2	2	NUM
hjic-1157	95	3	:	:	PUNCT
hjic-1157	95	4	kinetics	kinetic	NOUN
hjic-1157	95	5	of	of	ADP
hjic-1157	95	6	the	the	DET
hjic-1157	95	7	whole	whole	ADJ
hjic-1157	95	8	-	-	PUNCT
hjic-1157	95	9	cell	cell	NOUN
hjic-1157	95	10	biocatalyst	biocatalyst	NOUN
hjic-1157	95	11	50	50	NUM
hjic-1157	95	12	pp	pp	NOUN
hjic-1157	95	13	.	.	PUNCT
hjic-1157	96	1	23–28	23–28	NUM
hjic-1157	96	2	(	(	PUNCT
hjic-1157	96	3	2022	2022	NUM
hjic-1157	96	4	)	)	PUNCT
hjic-1157	96	5	26	26	NUM
hjic-1157	96	6	lajtai	lajtai	NOUN
hjic-1157	96	7	-	-	PUNCT
hjic-1157	96	8	szabó	szabó	NOUN
hjic-1157	96	9	,	,	PUNCT
hjic-1157	96	10	bagó	bagó	PROPN
hjic-1157	96	11	and	and	CCONJ
hjic-1157	96	12	nemestóthy	nemestóthy	ADJ
hjic-1157	96	13	figure	figure	NOUN
hjic-1157	96	14	3	3	NUM
hjic-1157	96	15	:	:	PUNCT
hjic-1157	96	16	biphasic	biphasic	ADJ
hjic-1157	96	17	enzyme	enzyme	NOUN
hjic-1157	96	18	kinetics	kinetic	NOUN
hjic-1157	96	19	[	[	X
hjic-1157	96	20	15	15	NUM
hjic-1157	96	21	]	]	PUNCT
hjic-1157	96	22	figure	figure	NOUN
hjic-1157	96	23	4	4	NUM
hjic-1157	96	24	:	:	PUNCT
hjic-1157	96	25	kinetics	kinetic	NOUN
hjic-1157	96	26	of	of	ADP
hjic-1157	96	27	the	the	DET
hjic-1157	96	28	isolated	isolate	VERB
hjic-1157	96	29	enzyme	enzyme	NOUN
hjic-1157	96	30	apart	apart	ADV
hjic-1157	96	31	from	from	ADP
hjic-1157	96	32	one	one	NUM
hjic-1157	96	33	exception	exception	NOUN
hjic-1157	96	34	(	(	PUNCT
hjic-1157	96	35	at	at	ADP
hjic-1157	96	36	0.22	0.22	NUM
hjic-1157	96	37	m	m	NOUN
hjic-1157	96	38	)	)	PUNCT
hjic-1157	96	39	,	,	PUNCT
hjic-1157	96	40	since	since	SCONJ
hjic-1157	96	41	model	model	NOUN
hjic-1157	96	42	data	datum	NOUN
hjic-1157	96	43	calculated	calculate	VERB
hjic-1157	96	44	using	use	VERB
hjic-1157	96	45	eq	eq	PROPN
hjic-1157	96	46	.	.	PROPN
hjic-1157	96	47	3	3	NUM
hjic-1157	96	48	fitted	fit	VERB
hjic-1157	96	49	well	well	ADV
hjic-1157	96	50	to	to	ADP
hjic-1157	96	51	the	the	DET
hjic-1157	96	52	measured	measured	ADJ
hjic-1157	96	53	data	datum	NOUN
hjic-1157	96	54	(	(	PUNCT
hjic-1157	96	55	fig	fig	NOUN
hjic-1157	96	56	.	.	PUNCT
hjic-1157	96	57	4	4	NUM
hjic-1157	96	58	)	)	PUNCT
hjic-1157	96	59	,	,	PUNCT
hjic-1157	96	60	biphasic	biphasic	ADJ
hjic-1157	96	61	kinetics	kinetic	NOUN
hjic-1157	96	62	is	be	AUX
hjic-1157	96	63	presumably	presumably	ADV
hjic-1157	96	64	a	a	DET
hjic-1157	96	65	suitable	suitable	ADJ
hjic-1157	96	66	model	model	NOUN
hjic-1157	96	67	to	to	PART
hjic-1157	96	68	describe	describe	VERB
hjic-1157	96	69	the	the	DET
hjic-1157	96	70	kinetics	kinetic	NOUN
hjic-1157	96	71	of	of	ADP
hjic-1157	96	72	an	an	DET
hjic-1157	96	73	isolated	isolated	ADJ
hjic-1157	96	74	enzyme	enzyme	NOUN
hjic-1157	96	75	.	.	PUNCT
hjic-1157	97	1	having	having	AUX
hjic-1157	97	2	been	be	AUX
hjic-1157	97	3	minimized	minimize	VERB
hjic-1157	97	4	by	by	ADP
hjic-1157	97	5	the	the	DET
hjic-1157	97	6	excel	excel	PROPN
hjic-1157	97	7	solver	solver	NOUN
hjic-1157	97	8	plug	plug	NOUN
hjic-1157	97	9	-	-	PUNCT
hjic-1157	97	10	in	in	NOUN
hjic-1157	97	11	,	,	PUNCT
hjic-1157	97	12	the	the	DET
hjic-1157	97	13	model	model	NOUN
hjic-1157	97	14	parameters	parameter	NOUN
hjic-1157	97	15	were	be	AUX
hjic-1157	97	16	the	the	DET
hjic-1157	97	17	following	following	NOUN
hjic-1157	97	18	:	:	PUNCT
hjic-1157	97	19	vmax1	vmax1	X
hjic-1157	98	1	=	=	SYM
hjic-1157	98	2	7.523	7.523	NUM
hjic-1157	98	3	;	;	PUNCT
hjic-1157	98	4	clint	clint	NOUN
hjic-1157	98	5	=	=	PROPN
hjic-1157	98	6	3.458	3.458	NUM
hjic-1157	98	7	;	;	PUNCT
hjic-1157	98	8	km1	km1	PROPN
hjic-1157	98	9	=	=	PROPN
hjic-1157	98	10	0.464	0.464	NUM
hjic-1157	98	11	.	.	PUNCT
hjic-1157	99	1	according	accord	VERB
hjic-1157	99	2	to	to	ADP
hjic-1157	99	3	manevski	manevski	NOUN
hjic-1157	99	4	[	[	X
hjic-1157	99	5	15	15	NUM
hjic-1157	99	6	]	]	PUNCT
hjic-1157	99	7	,	,	PUNCT
hjic-1157	99	8	biphasic	biphasic	ADJ
hjic-1157	99	9	kinetics	kinetic	NOUN
hjic-1157	99	10	may	may	AUX
hjic-1157	99	11	imply	imply	VERB
hjic-1157	99	12	the	the	DET
hjic-1157	99	13	presence	presence	NOUN
hjic-1157	99	14	of	of	ADP
hjic-1157	99	15	multiple	multiple	ADJ
hjic-1157	99	16	substrate	substrate	NOUN
hjic-1157	99	17	binding	bind	VERB
hjic-1157	99	18	sites	site	NOUN
hjic-1157	99	19	.	.	PUNCT
hjic-1157	100	1	however	however	ADV
hjic-1157	100	2	,	,	PUNCT
hjic-1157	100	3	the	the	DET
hjic-1157	100	4	applied	apply	VERB
hjic-1157	100	5	methods	method	NOUN
hjic-1157	100	6	were	be	AUX
hjic-1157	100	7	unsuitable	unsuitable	ADJ
hjic-1157	100	8	for	for	ADP
hjic-1157	100	9	further	far	ADV
hjic-1157	100	10	investigating	investigate	VERB
hjic-1157	100	11	the	the	DET
hjic-1157	100	12	underlying	underlying	ADJ
hjic-1157	100	13	mechanisms	mechanism	NOUN
hjic-1157	100	14	of	of	ADP
hjic-1157	100	15	the	the	DET
hjic-1157	100	16	reactions	reaction	NOUN
hjic-1157	100	17	taking	take	VERB
hjic-1157	100	18	place	place	NOUN
hjic-1157	100	19	.	.	PUNCT
hjic-1157	101	1	3.2	3.2	NUM
hjic-1157	101	2	activity	activity	NOUN
hjic-1157	101	3	the	the	DET
hjic-1157	101	4	activity	activity	NOUN
hjic-1157	101	5	of	of	ADP
hjic-1157	101	6	the	the	DET
hjic-1157	101	7	catalysts	catalyst	NOUN
hjic-1157	101	8	was	be	AUX
hjic-1157	101	9	measured	measure	VERB
hjic-1157	101	10	during	during	ADP
hjic-1157	101	11	both	both	PRON
hjic-1157	101	12	cofactor	cofactor	NOUN
hjic-1157	101	13	regeneration	regeneration	NOUN
hjic-1157	101	14	and	and	CCONJ
hjic-1157	101	15	the	the	DET
hjic-1157	101	16	process	process	NOUN
hjic-1157	101	17	as	as	ADP
hjic-1157	101	18	a	a	DET
hjic-1157	101	19	whole	whole	ADJ
hjic-1157	101	20	(	(	PUNCT
hjic-1157	101	21	table	table	NOUN
hjic-1157	101	22	2	2	NUM
hjic-1157	101	23	)	)	PUNCT
hjic-1157	101	24	.	.	PUNCT
hjic-1157	102	1	one	one	NUM
hjic-1157	102	2	unit	unit	NOUN
hjic-1157	102	3	(	(	PUNCT
hjic-1157	102	4	u	u	NOUN
hjic-1157	102	5	)	)	PUNCT
hjic-1157	102	6	stands	stand	VERB
hjic-1157	102	7	for	for	ADP
hjic-1157	102	8	the	the	DET
hjic-1157	102	9	amount	amount	NOUN
hjic-1157	102	10	of	of	ADP
hjic-1157	102	11	catalyst	catalyst	NOUN
hjic-1157	102	12	necessary	necessary	ADJ
hjic-1157	102	13	to	to	PART
hjic-1157	102	14	produce	produce	VERB
hjic-1157	102	15	1	1	NUM
hjic-1157	102	16	µmol	µmol	NOUN
hjic-1157	102	17	of	of	ADP
hjic-1157	102	18	product	product	NOUN
hjic-1157	102	19	in	in	ADP
hjic-1157	102	20	1	1	NUM
hjic-1157	102	21	minute	minute	NOUN
hjic-1157	102	22	under	under	ADP
hjic-1157	102	23	the	the	DET
hjic-1157	102	24	measurement	measurement	NOUN
hjic-1157	102	25	parameters	parameter	NOUN
hjic-1157	102	26	.	.	PUNCT
hjic-1157	103	1	(	(	PUNCT
hjic-1157	103	2	substrate	substrate	NOUN
hjic-1157	103	3	conversion	conversion	NOUN
hjic-1157	103	4	could	could	AUX
hjic-1157	103	5	not	not	PART
hjic-1157	103	6	be	be	AUX
hjic-1157	103	7	investigated	investigate	VERB
hjic-1157	103	8	separately	separately	ADV
hjic-1157	103	9	as	as	SCONJ
hjic-1157	103	10	previously	previously	ADV
hjic-1157	103	11	mentioned	mention	VERB
hjic-1157	103	12	in	in	ADP
hjic-1157	103	13	sec	sec	PROPN
hjic-1157	103	14	.	.	PROPN
hjic-1157	103	15	2.2	2.2	NUM
hjic-1157	103	16	)	)	PUNCT
hjic-1157	103	17	.	.	PUNCT
hjic-1157	104	1	although	although	SCONJ
hjic-1157	104	2	normally	normally	ADV
hjic-1157	104	3	the	the	DET
hjic-1157	104	4	catalytic	catalytic	ADJ
hjic-1157	104	5	activity	activity	NOUN
hjic-1157	104	6	should	should	AUX
hjic-1157	104	7	be	be	AUX
hjic-1157	104	8	measured	measure	VERB
hjic-1157	104	9	in	in	ADP
hjic-1157	104	10	the	the	DET
hjic-1157	104	11	saturation	saturation	NOUN
hjic-1157	104	12	phase	phase	NOUN
hjic-1157	104	13	of	of	ADP
hjic-1157	104	14	the	the	DET
hjic-1157	104	15	kinetics	kinetic	NOUN
hjic-1157	104	16	,	,	PUNCT
hjic-1157	104	17	none	none	NOUN
hjic-1157	104	18	of	of	ADP
hjic-1157	104	19	the	the	DET
hjic-1157	104	20	kinetic	kinetic	ADJ
hjic-1157	104	21	curves	curve	NOUN
hjic-1157	104	22	enabled	enable	VERB
hjic-1157	104	23	this	this	PRON
hjic-1157	104	24	.	.	PUNCT
hjic-1157	105	1	therefore	therefore	ADV
hjic-1157	105	2	,	,	PUNCT
hjic-1157	105	3	measurements	measurement	NOUN
hjic-1157	105	4	were	be	AUX
hjic-1157	105	5	made	make	VERB
hjic-1157	105	6	at	at	ADP
hjic-1157	105	7	a	a	DET
hjic-1157	105	8	substrate	substrate	NOUN
hjic-1157	105	9	concentration	concentration	NOUN
hjic-1157	105	10	of	of	ADP
hjic-1157	105	11	0.27	0.27	NUM
hjic-1157	105	12	m	m	NOUN
hjic-1157	105	13	,	,	PUNCT
hjic-1157	105	14	which	which	PRON
hjic-1157	105	15	is	be	AUX
hjic-1157	105	16	the	the	DET
hjic-1157	105	17	substrate	substrate	NOUN
hjic-1157	105	18	concentration	concentration	NOUN
hjic-1157	105	19	at	at	ADP
hjic-1157	105	20	which	which	PRON
hjic-1157	105	21	the	the	DET
hjic-1157	105	22	kinetic	kinetic	ADJ
hjic-1157	105	23	table	table	NOUN
hjic-1157	105	24	2	2	NUM
hjic-1157	105	25	:	:	PUNCT
hjic-1157	105	26	activity	activity	NOUN
hjic-1157	105	27	of	of	ADP
hjic-1157	105	28	the	the	DET
hjic-1157	105	29	catalysts	catalyst	NOUN
hjic-1157	105	30	yeast	yeast	NOUN
hjic-1157	105	31	cell	cell	NOUN
hjic-1157	105	32	[	[	X
hjic-1157	105	33	u	u	NOUN
hjic-1157	105	34	/	/	SYM
hjic-1157	105	35	mg	mg	PROPN
hjic-1157	105	36	]	]	PUNCT
hjic-1157	105	37	recombinant	recombinant	ADJ
hjic-1157	105	38	adh	adh	NOUN
hjic-1157	105	39	[	[	X
hjic-1157	105	40	u	u	NOUN
hjic-1157	105	41	/	/	SYM
hjic-1157	105	42	mg	mg	NOUN
hjic-1157	105	43	]	]	PUNCT
hjic-1157	105	44	cofactor	cofactor	NOUN
hjic-1157	105	45	regeneration	regeneration	NOUN
hjic-1157	105	46	0.19	0.19	NUM
hjic-1157	105	47	0.05	0.05	NUM
hjic-1157	105	48	complete	complete	ADJ
hjic-1157	105	49	reaction	reaction	NOUN
hjic-1157	105	50	(	(	PUNCT
hjic-1157	105	51	0.27	0.27	NUM
hjic-1157	105	52	m	m	NOUN
hjic-1157	105	53	)	)	PUNCT
hjic-1157	105	54	0.02	0.02	NUM
hjic-1157	105	55	0.7	0.7	NUM
hjic-1157	105	56	complete	complete	ADJ
hjic-1157	105	57	reaction	reaction	NOUN
hjic-1157	105	58	(	(	PUNCT
hjic-1157	105	59	1.08	1.08	NUM
hjic-1157	105	60	m	m	NOUN
hjic-1157	105	61	)	)	PUNCT
hjic-1157	105	62	–	–	PUNCT
hjic-1157	105	63	1.64	1.64	NUM
hjic-1157	105	64	curve	curve	NOUN
hjic-1157	105	65	of	of	ADP
hjic-1157	105	66	the	the	DET
hjic-1157	105	67	yeast	yeast	NOUN
hjic-1157	105	68	-	-	PUNCT
hjic-1157	105	69	cell	cell	NOUN
hjic-1157	105	70	catalyst	catalyst	NOUN
hjic-1157	105	71	is	be	AUX
hjic-1157	105	72	at	at	ADP
hjic-1157	105	73	its	its	PRON
hjic-1157	105	74	maximum	maximum	NOUN
hjic-1157	105	75	.	.	PUNCT
hjic-1157	106	1	in	in	ADP
hjic-1157	106	2	the	the	DET
hjic-1157	106	3	case	case	NOUN
hjic-1157	106	4	of	of	ADP
hjic-1157	106	5	the	the	DET
hjic-1157	106	6	isolated	isolated	ADJ
hjic-1157	106	7	enzyme	enzyme	NOUN
hjic-1157	106	8	,	,	PUNCT
hjic-1157	106	9	the	the	DET
hjic-1157	106	10	activity	activity	NOUN
hjic-1157	106	11	was	be	AUX
hjic-1157	106	12	measured	measure	VERB
hjic-1157	106	13	at	at	ADP
hjic-1157	106	14	the	the	DET
hjic-1157	106	15	same	same	ADJ
hjic-1157	106	16	concentration	concentration	NOUN
hjic-1157	106	17	as	as	ADP
hjic-1157	106	18	that	that	PRON
hjic-1157	106	19	of	of	ADP
hjic-1157	106	20	yeast	yeast	NOUN
hjic-1157	106	21	in	in	ADP
hjic-1157	106	22	order	order	NOUN
hjic-1157	106	23	to	to	PART
hjic-1157	106	24	compare	compare	VERB
hjic-1157	106	25	the	the	DET
hjic-1157	106	26	two	two	NUM
hjic-1157	106	27	catalysts	catalyst	NOUN
hjic-1157	106	28	.	.	PUNCT
hjic-1157	107	1	this	this	PRON
hjic-1157	107	2	was	be	AUX
hjic-1157	107	3	also	also	ADV
hjic-1157	107	4	determined	determine	VERB
hjic-1157	107	5	at	at	ADP
hjic-1157	107	6	the	the	DET
hjic-1157	107	7	highest	high	ADJ
hjic-1157	107	8	measured	measured	ADJ
hjic-1157	107	9	point	point	NOUN
hjic-1157	107	10	of	of	ADP
hjic-1157	107	11	the	the	DET
hjic-1157	107	12	kinetic	kinetic	ADJ
hjic-1157	107	13	curve	curve	NOUN
hjic-1157	107	14	,	,	PUNCT
hjic-1157	107	15	namely	namely	ADV
hjic-1157	107	16	at	at	ADP
hjic-1157	107	17	1.08	1.08	NUM
hjic-1157	107	18	m.	m.	NOUN
hjic-1157	107	19	based	base	VERB
hjic-1157	107	20	on	on	ADP
hjic-1157	107	21	the	the	DET
hjic-1157	107	22	results	result	NOUN
hjic-1157	107	23	,	,	PUNCT
hjic-1157	107	24	cofactor	cofactor	NOUN
hjic-1157	107	25	regeneration	regeneration	NOUN
hjic-1157	107	26	is	be	AUX
hjic-1157	107	27	one	one	NUM
hjic-1157	107	28	scale	scale	NOUN
hjic-1157	107	29	faster	fast	ADV
hjic-1157	107	30	when	when	SCONJ
hjic-1157	107	31	applying	apply	VERB
hjic-1157	107	32	a	a	DET
hjic-1157	107	33	whole	whole	ADJ
hjic-1157	107	34	-	-	PUNCT
hjic-1157	107	35	cell	cell	NOUN
hjic-1157	107	36	biocatalyst	biocatalyst	NOUN
hjic-1157	107	37	instead	instead	ADV
hjic-1157	107	38	of	of	ADP
hjic-1157	107	39	an	an	DET
hjic-1157	107	40	isolated	isolated	ADJ
hjic-1157	107	41	enzyme	enzyme	NOUN
hjic-1157	107	42	.	.	PUNCT
hjic-1157	108	1	although	although	SCONJ
hjic-1157	108	2	the	the	DET
hjic-1157	108	3	same	same	ADJ
hjic-1157	108	4	enzyme	enzyme	NOUN
hjic-1157	108	5	catalyses	catalysis	NOUN
hjic-1157	108	6	both	both	DET
hjic-1157	108	7	substrate	substrate	NOUN
hjic-1157	108	8	conversion	conversion	NOUN
hjic-1157	108	9	and	and	CCONJ
hjic-1157	108	10	cofactor	cofactor	NOUN
hjic-1157	108	11	regeneration	regeneration	NOUN
hjic-1157	108	12	when	when	SCONJ
hjic-1157	108	13	isolated	isolated	ADJ
hjic-1157	108	14	adh	adh	NOUN
hjic-1157	108	15	is	be	AUX
hjic-1157	108	16	used	use	VERB
hjic-1157	108	17	,	,	PUNCT
hjic-1157	108	18	yeast	yeast	NOUN
hjic-1157	108	19	cells	cell	NOUN
hjic-1157	108	20	contain	contain	VERB
hjic-1157	108	21	several	several	ADJ
hjic-1157	108	22	enzymes	enzyme	NOUN
hjic-1157	108	23	that	that	PRON
hjic-1157	108	24	are	be	AUX
hjic-1157	108	25	capable	capable	ADJ
hjic-1157	108	26	of	of	ADP
hjic-1157	108	27	participating	participate	VERB
hjic-1157	108	28	in	in	ADP
hjic-1157	108	29	regeneration	regeneration	NOUN
hjic-1157	108	30	reactions	reaction	NOUN
hjic-1157	108	31	which	which	PRON
hjic-1157	108	32	can	can	AUX
hjic-1157	108	33	occur	occur	VERB
hjic-1157	108	34	more	more	ADV
hjic-1157	108	35	rapidly	rapidly	ADV
hjic-1157	108	36	as	as	ADP
hjic-1157	108	37	a	a	DET
hjic-1157	108	38	result	result	NOUN
hjic-1157	108	39	.	.	PUNCT
hjic-1157	109	1	on	on	ADP
hjic-1157	109	2	the	the	DET
hjic-1157	109	3	other	other	ADJ
hjic-1157	109	4	hand	hand	NOUN
hjic-1157	109	5	,	,	PUNCT
hjic-1157	109	6	the	the	DET
hjic-1157	109	7	overall	overall	ADJ
hjic-1157	109	8	reaction	reaction	NOUN
hjic-1157	109	9	rate	rate	NOUN
hjic-1157	109	10	using	use	VERB
hjic-1157	109	11	the	the	DET
hjic-1157	109	12	same	same	ADJ
hjic-1157	109	13	substrate	substrate	NOUN
hjic-1157	109	14	concentration	concentration	NOUN
hjic-1157	109	15	was	be	AUX
hjic-1157	109	16	35	35	NUM
hjic-1157	109	17	times	time	NOUN
hjic-1157	109	18	higher	high	ADJ
hjic-1157	109	19	when	when	SCONJ
hjic-1157	109	20	recombinant	recombinant	ADJ
hjic-1157	109	21	adh	adh	NOUN
hjic-1157	109	22	was	be	AUX
hjic-1157	109	23	used	use	VERB
hjic-1157	109	24	and	and	CCONJ
hjic-1157	109	25	further	further	ADJ
hjic-1157	109	26	increases	increase	NOUN
hjic-1157	109	27	in	in	ADP
hjic-1157	109	28	substrate	substrate	NOUN
hjic-1157	109	29	concentration	concentration	NOUN
hjic-1157	109	30	resulted	result	VERB
hjic-1157	109	31	in	in	ADP
hjic-1157	109	32	even	even	ADV
hjic-1157	109	33	higher	high	ADJ
hjic-1157	109	34	reaction	reaction	NOUN
hjic-1157	109	35	rates	rate	NOUN
hjic-1157	109	36	.	.	PUNCT
hjic-1157	110	1	3.3	3.3	NUM
hjic-1157	110	2	mass	mass	NOUN
hjic-1157	110	3	transfer	transfer	NOUN
hjic-1157	110	4	through	through	ADP
hjic-1157	110	5	the	the	DET
hjic-1157	110	6	organic	organic	ADJ
hjic-1157	110	7	–	–	PUNCT
hjic-1157	110	8	water	water	NOUN
hjic-1157	110	9	interface	interface	NOUN
hjic-1157	110	10	in	in	ADP
hjic-1157	110	11	order	order	NOUN
hjic-1157	110	12	to	to	PART
hjic-1157	110	13	determine	determine	VERB
hjic-1157	110	14	the	the	DET
hjic-1157	110	15	rate	rate	NOUN
hjic-1157	110	16	-	-	PUNCT
hjic-1157	110	17	limiting	limit	VERB
hjic-1157	110	18	step	step	NOUN
hjic-1157	110	19	of	of	ADP
hjic-1157	110	20	the	the	DET
hjic-1157	110	21	whole	whole	ADJ
hjic-1157	110	22	process	process	NOUN
hjic-1157	110	23	,	,	PUNCT
hjic-1157	110	24	the	the	DET
hjic-1157	110	25	mass	mass	NOUN
hjic-1157	110	26	transfer	transfer	NOUN
hjic-1157	110	27	rate	rate	NOUN
hjic-1157	110	28	through	through	ADP
hjic-1157	110	29	an	an	DET
hjic-1157	110	30	organic	organic	ADJ
hjic-1157	110	31	–	–	PUNCT
hjic-1157	110	32	water	water	NOUN
hjic-1157	110	33	interface	interface	NOUN
hjic-1157	110	34	was	be	AUX
hjic-1157	110	35	investigated	investigate	VERB
hjic-1157	110	36	.	.	PUNCT
hjic-1157	111	1	owing	owe	VERB
hjic-1157	111	2	to	to	ADP
hjic-1157	111	3	simplifications	simplification	NOUN
hjic-1157	111	4	of	of	ADP
hjic-1157	111	5	the	the	DET
hjic-1157	111	6	measurement	measurement	NOUN
hjic-1157	111	7	and	and	CCONJ
hjic-1157	111	8	the	the	DET
hjic-1157	111	9	imprecise	imprecise	ADJ
hjic-1157	111	10	nature	nature	NOUN
hjic-1157	111	11	of	of	ADP
hjic-1157	111	12	model	model	NOUN
hjic-1157	111	13	fitting	fitting	PROPN
hjic-1157	111	14	,	,	PUNCT
hjic-1157	111	15	the	the	DET
hjic-1157	111	16	calculated	calculated	ADJ
hjic-1157	111	17	mass	mass	NOUN
hjic-1157	111	18	transfer	transfer	NOUN
hjic-1157	111	19	rate	rate	NOUN
hjic-1157	111	20	may	may	AUX
hjic-1157	111	21	be	be	AUX
hjic-1157	111	22	somewhat	somewhat	ADV
hjic-1157	111	23	inaccurate	inaccurate	ADJ
hjic-1157	111	24	.	.	PUNCT
hjic-1157	112	1	nevertheless	nevertheless	ADV
hjic-1157	112	2	,	,	PUNCT
hjic-1157	112	3	the	the	DET
hjic-1157	112	4	goal	goal	NOUN
hjic-1157	112	5	was	be	AUX
hjic-1157	112	6	to	to	PART
hjic-1157	112	7	estimate	estimate	VERB
hjic-1157	112	8	its	its	PRON
hjic-1157	112	9	order	order	NOUN
hjic-1157	112	10	of	of	ADP
hjic-1157	112	11	magnitude	magnitude	NOUN
hjic-1157	112	12	rather	rather	ADV
hjic-1157	112	13	than	than	ADP
hjic-1157	112	14	determining	determine	VERB
hjic-1157	112	15	its	its	PRON
hjic-1157	112	16	precise	precise	ADJ
hjic-1157	112	17	value	value	NOUN
hjic-1157	112	18	.	.	PUNCT
hjic-1157	113	1	based	base	VERB
hjic-1157	113	2	on	on	ADP
hjic-1157	113	3	the	the	DET
hjic-1157	113	4	kinetic	kinetic	ADJ
hjic-1157	113	5	model	model	NOUN
hjic-1157	113	6	fitted	fit	VERB
hjic-1157	113	7	to	to	ADP
hjic-1157	113	8	the	the	DET
hjic-1157	113	9	measured	measured	ADJ
hjic-1157	113	10	data	datum	NOUN
hjic-1157	113	11	(	(	PUNCT
hjic-1157	113	12	fig	fig	NOUN
hjic-1157	113	13	.	.	PUNCT
hjic-1157	113	14	5	5	NUM
hjic-1157	113	15	)	)	PUNCT
hjic-1157	113	16	,	,	PUNCT
hjic-1157	113	17	the	the	DET
hjic-1157	113	18	mass	mass	NOUN
hjic-1157	113	19	transfer	transfer	NOUN
hjic-1157	113	20	rate	rate	NOUN
hjic-1157	113	21	was	be	AUX
hjic-1157	113	22	calculated	calculate	VERB
hjic-1157	113	23	to	to	PART
hjic-1157	113	24	be	be	AUX
hjic-1157	113	25	1.33	1.33	NUM
hjic-1157	113	26	·	·	SYM
hjic-1157	113	27	10−5	10−5	NUM
hjic-1157	113	28	mol	mol	PROPN
hjic-1157	113	29	/	/	SYM
hjic-1157	113	30	min	min	PROPN
hjic-1157	113	31	.	.	NOUN
hjic-1157	113	32	by	by	ADP
hjic-1157	113	33	comparing	compare	VERB
hjic-1157	113	34	this	this	DET
hjic-1157	113	35	value	value	NOUN
hjic-1157	113	36	with	with	ADP
hjic-1157	113	37	the	the	DET
hjic-1157	113	38	figure	figure	NOUN
hjic-1157	113	39	5	5	NUM
hjic-1157	113	40	:	:	PUNCT
hjic-1157	113	41	mass	mass	NOUN
hjic-1157	113	42	transfer	transfer	NOUN
hjic-1157	113	43	process	process	NOUN
hjic-1157	113	44	hungarian	hungarian	ADJ
hjic-1157	113	45	journal	journal	NOUN
hjic-1157	113	46	of	of	ADP
hjic-1157	113	47	industry	industry	NOUN
hjic-1157	113	48	and	and	CCONJ
hjic-1157	113	49	chemistry	chemistry	NOUN
hjic-1157	113	50	production	production	NOUN
hjic-1157	113	51	of	of	ADP
hjic-1157	113	52	chiral	chiral	ADJ
hjic-1157	113	53	(	(	PUNCT
hjic-1157	113	54	s)-2	s)-2	NOUN
hjic-1157	113	55	-	-	PUNCT
hjic-1157	113	56	phenyl-1	phenyl-1	NOUN
hjic-1157	113	57	-	-	PUNCT
hjic-1157	113	58	propanol	propanol	ADJ
hjic-1157	113	59	27	27	NUM
hjic-1157	113	60	table	table	NOUN
hjic-1157	113	61	3	3	NUM
hjic-1157	113	62	:	:	PUNCT
hjic-1157	113	63	enantiomeric	enantiomeric	ADJ
hjic-1157	113	64	excess	excess	NOUN
hjic-1157	113	65	(	(	PUNCT
hjic-1157	113	66	ee	ee	NOUN
hjic-1157	113	67	)	)	PUNCT
hjic-1157	113	68	and	and	CCONJ
hjic-1157	113	69	degree	degree	NOUN
hjic-1157	113	70	of	of	ADP
hjic-1157	113	71	conversion	conversion	NOUN
hjic-1157	113	72	from	from	ADP
hjic-1157	113	73	studies	study	NOUN
hjic-1157	113	74	on	on	ADP
hjic-1157	113	75	the	the	DET
hjic-1157	113	76	production	production	NOUN
hjic-1157	113	77	of	of	ADP
hjic-1157	113	78	(	(	PUNCT
hjic-1157	113	79	s)-2	s)-2	NOUN
hjic-1157	113	80	-	-	PUNCT
hjic-1157	113	81	phenyl-1	phenyl-1	ADP
hjic-1157	113	82	-	-	PUNCT
hjic-1157	113	83	propanol	propanol	ADJ
hjic-1157	113	84	catalyst	catalyst	NOUN
hjic-1157	113	85	solvent	solvent	NOUN
hjic-1157	113	86	substrate	substrate	NOUN
hjic-1157	113	87	conc	conc	NOUN
hjic-1157	113	88	.	.	PUNCT
hjic-1157	114	1	product	product	NOUN
hjic-1157	114	2	,	,	PUNCT
hjic-1157	114	3	degree	degree	NOUN
hjic-1157	114	4	of	of	ADP
hjic-1157	114	5	conversion	conversion	NOUN
hjic-1157	114	6	ee	ee	PROPN
hjic-1157	114	7	(	(	PUNCT
hjic-1157	114	8	s	s	NOUN
hjic-1157	114	9	)	)	PUNCT
hjic-1157	114	10	ref	ref	NOUN
hjic-1157	114	11	.	.	PUNCT
hjic-1157	115	1	horse	horse	NOUN
hjic-1157	115	2	-	-	PUNCT
hjic-1157	115	3	liver	liver	NOUN
hjic-1157	115	4	adh	adh	NOUN
hjic-1157	115	5	0.24	0.24	NUM
hjic-1157	115	6	u	u	NOUN
hjic-1157	115	7	/	/	SYM
hjic-1157	115	8	ml	ml	NOUN
hjic-1157	115	9	buffer	buffer	NOUN
hjic-1157	115	10	,	,	PUNCT
hjic-1157	115	11	165	165	NUM
hjic-1157	115	12	mm	mm	NUM
hjic-1157	115	13	41	41	NUM
hjic-1157	115	14	mm	mm	NOUN
hjic-1157	115	15	,	,	PUNCT
hjic-1157	115	16	25	25	NUM
hjic-1157	115	17	%	%	NOUN
hjic-1157	115	18	(	(	PUNCT
hjic-1157	115	19	2	2	NUM
hjic-1157	115	20	h	h	NOUN
hjic-1157	115	21	)	)	PUNCT
hjic-1157	116	1	91	91	NUM
hjic-1157	116	2	%	%	NOUN
hjic-1157	116	3	[	[	X
hjic-1157	116	4	14]isopropyl	14]isopropyl	NUM
hjic-1157	116	5	ether	ether	NOUN
hjic-1157	116	6	(	(	PUNCT
hjic-1157	116	7	63	63	NUM
hjic-1157	116	8	%	%	NOUN
hjic-1157	116	9	v	v	ADP
hjic-1157	116	10	/	/	SYM
hjic-1157	116	11	v	v	NOUN
hjic-1157	116	12	)	)	PUNCT
hjic-1157	116	13	82	82	NUM
hjic-1157	116	14	mm	mm	NOUN
hjic-1157	116	15	,	,	PUNCT
hjic-1157	116	16	50	50	NUM
hjic-1157	116	17	%	%	NOUN
hjic-1157	116	18	(	(	PUNCT
hjic-1157	116	19	24	24	NUM
hjic-1157	116	20	h	h	NOUN
hjic-1157	116	21	)	)	PUNCT
hjic-1157	116	22	88	88	NUM
hjic-1157	116	23	%	%	NOUN
hjic-1157	116	24	horse	horse	NOUN
hjic-1157	116	25	-	-	PUNCT
hjic-1157	116	26	liver	liver	NOUN
hjic-1157	116	27	adh	adh	NOUN
hjic-1157	116	28	0.01	0.01	NUM
hjic-1157	116	29	mg	mg	PROPN
hjic-1157	116	30	/	/	SYM
hjic-1157	116	31	ml	ml	NOUN
hjic-1157	116	32	buffer	buffer	NOUN
hjic-1157	116	33	ph=	ph=	NOUN
hjic-1157	116	34	7.5	7.5	NUM
hjic-1157	116	35	,	,	PUNCT
hjic-1157	116	36	ch3cn	ch3cn	NUM
hjic-1157	116	37	(	(	PUNCT
hjic-1157	116	38	10	10	NUM
hjic-1157	116	39	%	%	NOUN
hjic-1157	116	40	v	v	ADP
hjic-1157	116	41	/	/	SYM
hjic-1157	116	42	v	v	NOUN
hjic-1157	116	43	)	)	PUNCT
hjic-1157	116	44	0.5	0.5	NUM
hjic-1157	116	45	mm	mm	NOUN
hjic-1157	116	46	0.36	0.36	NUM
hjic-1157	116	47	mm	mm	PROPN
hjic-1157	116	48	,	,	PUNCT
hjic-1157	116	49	72	72	NUM
hjic-1157	116	50	%	%	NOUN
hjic-1157	116	51	(	(	PUNCT
hjic-1157	116	52	5	5	NUM
hjic-1157	116	53	h	h	NOUN
hjic-1157	116	54	)	)	PUNCT
hjic-1157	116	55	78	78	NUM
hjic-1157	116	56	%	%	NOUN
hjic-1157	117	1	[	[	X
hjic-1157	117	2	12	12	NUM
hjic-1157	117	3	]	]	PUNCT
hjic-1157	117	4	recombinant	recombinant	ADJ
hjic-1157	117	5	horse	horse	NOUN
hjic-1157	117	6	-	-	PUNCT
hjic-1157	117	7	liver	liver	NOUN
hjic-1157	117	8	adh	adh	NOUN
hjic-1157	117	9	,	,	PUNCT
hjic-1157	117	10	exp	exp	NOUN
hjic-1157	117	11	.	.	PUNCT
hjic-1157	118	1	in	in	ADP
hjic-1157	118	2	e.	e.	PROPN
hjic-1157	118	3	coli	coli	PROPN
hjic-1157	118	4	0.5	0.5	NUM
hjic-1157	118	5	u	u	NOUN
hjic-1157	118	6	/	/	SYM
hjic-1157	118	7	ml	ml	X
hjic-1157	118	8	buffer	buffer	NOUN
hjic-1157	118	9	ph=	ph=	NOUN
hjic-1157	118	10	8.0	8.0	NUM
hjic-1157	118	11	,	,	PUNCT
hjic-1157	118	12	diisopropyl	diisopropyl	NOUN
hjic-1157	118	13	ether	ether	NOUN
hjic-1157	118	14	(	(	PUNCT
hjic-1157	118	15	1:1	1:1	NUM
hjic-1157	118	16	v	v	NOUN
hjic-1157	118	17	/	/	SYM
hjic-1157	118	18	v	v	NOUN
hjic-1157	118	19	)	)	PUNCT
hjic-1157	118	20	267	267	NUM
hjic-1157	118	21	mm	mm	NUM
hjic-1157	118	22	45	45	NUM
hjic-1157	118	23	mm	mm	PROPN
hjic-1157	118	24	,	,	PUNCT
hjic-1157	118	25	17	17	NUM
hjic-1157	118	26	%	%	NOUN
hjic-1157	118	27	(	(	PUNCT
hjic-1157	118	28	1	1	NUM
hjic-1157	118	29	h	h	NOUN
hjic-1157	118	30	)	)	PUNCT
hjic-1157	118	31	100	100	NUM
hjic-1157	118	32	%	%	NOUN
hjic-1157	118	33	this	this	DET
hjic-1157	118	34	work	work	NOUN
hjic-1157	118	35	ctxr	ctxr	VERB
hjic-1157	118	36	d51a	d51a	NOUN
hjic-1157	118	37	mutant	mutant	PROPN
hjic-1157	118	38	e.	e.	PROPN
hjic-1157	118	39	coli	coli	PROPN
hjic-1157	118	40	,	,	PUNCT
hjic-1157	118	41	4	4	NUM
hjic-1157	118	42	gcdw	gcdw	NOUN
hjic-1157	118	43	/	/	SYM
hjic-1157	118	44	l	l	NOUN
hjic-1157	118	45	buffer	buffer	NOUN
hjic-1157	118	46	ph=	ph=	NOUN
hjic-1157	118	47	7.5	7.5	NUM
hjic-1157	118	48	100	100	NUM
hjic-1157	118	49	mm	mm	NUM
hjic-1157	118	50	41	41	NUM
hjic-1157	118	51	mm	mm	NOUN
hjic-1157	118	52	,	,	PUNCT
hjic-1157	118	53	41	41	NUM
hjic-1157	118	54	%	%	NOUN
hjic-1157	118	55	(	(	PUNCT
hjic-1157	118	56	2	2	NUM
hjic-1157	118	57	h	h	NOUN
hjic-1157	118	58	)	)	PUNCT
hjic-1157	118	59	95	95	NUM
hjic-1157	118	60	%	%	NOUN
hjic-1157	119	1	[	[	X
hjic-1157	119	2	2	2	NUM
hjic-1157	119	3	]	]	X
hjic-1157	119	4	whole	whole	ADJ
hjic-1157	119	5	-	-	PUNCT
hjic-1157	119	6	cell	cell	NOUN
hjic-1157	119	7	40	40	NUM
hjic-1157	119	8	gcdw	gcdw	NOUN
hjic-1157	119	9	/	/	SYM
hjic-1157	119	10	l	l	NOUN
hjic-1157	119	11	70	70	NUM
hjic-1157	119	12	mm	mm	NOUN
hjic-1157	119	13	,	,	PUNCT
hjic-1157	119	14	70	70	NUM
hjic-1157	119	15	%	%	NOUN
hjic-1157	119	16	(	(	PUNCT
hjic-1157	119	17	2	2	NUM
hjic-1157	119	18	h	h	NOUN
hjic-1157	119	19	)	)	PUNCT
hjic-1157	119	20	45	45	NUM
hjic-1157	119	21	%	%	NOUN
hjic-1157	119	22	s.	s.	PROPN
hjic-1157	119	23	cerevisiae	cerevisiae	PROPN
hjic-1157	119	24	,	,	PUNCT
hjic-1157	119	25	43	43	NUM
hjic-1157	119	26	gcdw	gcdw	NOUN
hjic-1157	119	27	/	/	SYM
hjic-1157	119	28	l	l	NOUN
hjic-1157	119	29	buffer	buffer	NOUN
hjic-1157	119	30	ph=	ph=	NOUN
hjic-1157	119	31	8.0	8.0	NUM
hjic-1157	119	32	,	,	PUNCT
hjic-1157	119	33	267	267	NUM
hjic-1157	119	34	mm	mm	NUM
hjic-1157	119	35	74	74	NUM
hjic-1157	119	36	mm	mm	NOUN
hjic-1157	119	37	,	,	PUNCT
hjic-1157	119	38	28	28	NUM
hjic-1157	119	39	%	%	NOUN
hjic-1157	119	40	(	(	PUNCT
hjic-1157	119	41	1	1	NUM
hjic-1157	119	42	h	h	NOUN
hjic-1157	119	43	)	)	PUNCT
hjic-1157	119	44	24	24	NUM
hjic-1157	119	45	%	%	NOUN
hjic-1157	119	46	this	this	DET
hjic-1157	119	47	work	work	NOUN
hjic-1157	119	48	whole	whole	ADJ
hjic-1157	119	49	-	-	PUNCT
hjic-1157	119	50	cell	cell	NOUN
hjic-1157	119	51	diisopropyl	diisopropyl	NOUN
hjic-1157	119	52	ether	ether	NOUN
hjic-1157	119	53	(	(	PUNCT
hjic-1157	119	54	1:1	1:1	NUM
hjic-1157	119	55	v	v	NOUN
hjic-1157	119	56	/	/	SYM
hjic-1157	119	57	v	v	NOUN
hjic-1157	119	58	)	)	PUNCT
hjic-1157	119	59	345	345	NUM
hjic-1157	119	60	mm	mm	NOUN
hjic-1157	119	61	55	55	NUM
hjic-1157	119	62	mm	mm	NOUN
hjic-1157	119	63	,	,	PUNCT
hjic-1157	119	64	16	16	NUM
hjic-1157	119	65	%	%	NOUN
hjic-1157	119	66	(	(	PUNCT
hjic-1157	119	67	1	1	NUM
hjic-1157	119	68	h	h	NOUN
hjic-1157	119	69	)	)	PUNCT
hjic-1157	119	70	36	36	NUM
hjic-1157	119	71	%	%	NOUN
hjic-1157	119	72	reaction	reaction	NOUN
hjic-1157	119	73	rates	rate	NOUN
hjic-1157	119	74	of	of	ADP
hjic-1157	119	75	both	both	DET
hjic-1157	119	76	catalysts	catalyst	NOUN
hjic-1157	119	77	,	,	PUNCT
hjic-1157	119	78	it	it	PRON
hjic-1157	119	79	could	could	AUX
hjic-1157	119	80	be	be	AUX
hjic-1157	119	81	established	establish	VERB
hjic-1157	119	82	that	that	SCONJ
hjic-1157	119	83	the	the	DET
hjic-1157	119	84	mass	mass	NOUN
hjic-1157	119	85	transfer	transfer	NOUN
hjic-1157	119	86	rate	rate	NOUN
hjic-1157	119	87	is	be	AUX
hjic-1157	119	88	two	two	NUM
hjic-1157	119	89	or	or	CCONJ
hjic-1157	119	90	three	three	NUM
hjic-1157	119	91	times	time	NOUN
hjic-1157	119	92	faster	fast	ADJ
hjic-1157	119	93	than	than	ADP
hjic-1157	119	94	those	those	PRON
hjic-1157	119	95	of	of	ADP
hjic-1157	119	96	product	product	NOUN
hjic-1157	119	97	formation	formation	NOUN
hjic-1157	119	98	or	or	CCONJ
hjic-1157	119	99	cofactor	cofactor	NOUN
hjic-1157	119	100	regeneration	regeneration	NOUN
hjic-1157	119	101	.	.	PUNCT
hjic-1157	120	1	therefore	therefore	ADV
hjic-1157	120	2	,	,	PUNCT
hjic-1157	120	3	the	the	DET
hjic-1157	120	4	rate	rate	NOUN
hjic-1157	120	5	-	-	PUNCT
hjic-1157	120	6	limiting	limit	VERB
hjic-1157	120	7	step	step	NOUN
hjic-1157	120	8	of	of	ADP
hjic-1157	120	9	the	the	DET
hjic-1157	120	10	whole	whole	ADJ
hjic-1157	120	11	process	process	NOUN
hjic-1157	120	12	is	be	AUX
hjic-1157	120	13	cofactor	cofactor	NOUN
hjic-1157	120	14	regeneration	regeneration	NOUN
hjic-1157	120	15	and	and	CCONJ
hjic-1157	120	16	substrate	substrate	NOUN
hjic-1157	120	17	conversion	conversion	NOUN
hjic-1157	120	18	when	when	SCONJ
hjic-1157	120	19	an	an	DET
hjic-1157	120	20	isolated	isolated	ADJ
hjic-1157	120	21	enzyme	enzyme	NOUN
hjic-1157	120	22	and	and	CCONJ
hjic-1157	120	23	whole	whole	ADJ
hjic-1157	120	24	-	-	PUNCT
hjic-1157	120	25	cell	cell	NOUN
hjic-1157	120	26	biocatalyst	biocatalyst	NOUN
hjic-1157	120	27	is	be	AUX
hjic-1157	120	28	applied	apply	VERB
hjic-1157	120	29	,	,	PUNCT
hjic-1157	120	30	respectively	respectively	ADV
hjic-1157	120	31	.	.	PUNCT
hjic-1157	121	1	3.4	3.4	NUM
hjic-1157	121	2	enantioselectivity	enantioselectivity	NOUN
hjic-1157	121	3	the	the	DET
hjic-1157	121	4	enantioselectivity	enantioselectivity	NOUN
hjic-1157	121	5	of	of	ADP
hjic-1157	121	6	the	the	DET
hjic-1157	121	7	whole	whole	ADJ
hjic-1157	121	8	-	-	PUNCT
hjic-1157	121	9	cell	cell	NOUN
hjic-1157	121	10	biocatalyst	biocatalyst	NOUN
hjic-1157	121	11	was	be	AUX
hjic-1157	121	12	measured	measure	VERB
hjic-1157	121	13	at	at	ADP
hjic-1157	121	14	three	three	NUM
hjic-1157	121	15	different	different	ADJ
hjic-1157	121	16	initial	initial	ADJ
hjic-1157	121	17	substrate	substrate	NOUN
hjic-1157	121	18	concentrations	concentration	NOUN
hjic-1157	121	19	:	:	PUNCT
hjic-1157	121	20	at	at	ADP
hjic-1157	121	21	the	the	DET
hjic-1157	121	22	maximum	maximum	NOUN
hjic-1157	121	23	of	of	ADP
hjic-1157	121	24	the	the	DET
hjic-1157	121	25	kinetic	kinetic	ADJ
hjic-1157	121	26	curve	curve	NOUN
hjic-1157	121	27	(	(	PUNCT
hjic-1157	121	28	0.267	0.267	NUM
hjic-1157	121	29	m	m	NOUN
hjic-1157	121	30	)	)	PUNCT
hjic-1157	121	31	as	as	ADV
hjic-1157	121	32	well	well	ADV
hjic-1157	121	33	as	as	ADP
hjic-1157	121	34	at	at	ADP
hjic-1157	121	35	two	two	NUM
hjic-1157	121	36	higher	high	ADJ
hjic-1157	121	37	values	value	NOUN
hjic-1157	121	38	(	(	PUNCT
hjic-1157	121	39	0.345	0.345	NUM
hjic-1157	121	40	m	m	NOUN
hjic-1157	121	41	and	and	CCONJ
hjic-1157	121	42	0.746	0.746	NUM
hjic-1157	121	43	m	m	NOUN
hjic-1157	121	44	)	)	PUNCT
hjic-1157	121	45	to	to	PART
hjic-1157	121	46	examine	examine	VERB
hjic-1157	121	47	whether	whether	SCONJ
hjic-1157	121	48	increasing	increase	VERB
hjic-1157	121	49	the	the	DET
hjic-1157	121	50	substrate	substrate	NOUN
hjic-1157	121	51	concentration	concentration	NOUN
hjic-1157	121	52	is	be	AUX
hjic-1157	121	53	beneficial	beneficial	ADJ
hjic-1157	121	54	as	as	ADV
hjic-1157	121	55	far	far	ADV
hjic-1157	121	56	as	as	SCONJ
hjic-1157	121	57	achieving	achieve	VERB
hjic-1157	121	58	optical	optical	ADJ
hjic-1157	121	59	purity	purity	NOUN
hjic-1157	121	60	is	be	AUX
hjic-1157	121	61	concerned	concern	VERB
hjic-1157	121	62	.	.	PUNCT
hjic-1157	122	1	the	the	DET
hjic-1157	122	2	enantiomeric	enantiomeric	ADJ
hjic-1157	122	3	ratio	ratio	NOUN
hjic-1157	122	4	was	be	AUX
hjic-1157	122	5	calculated	calculate	VERB
hjic-1157	122	6	from	from	ADP
hjic-1157	122	7	the	the	DET
hjic-1157	122	8	ratio	ratio	NOUN
hjic-1157	122	9	of	of	ADP
hjic-1157	122	10	the	the	DET
hjic-1157	122	11	peak	peak	NOUN
hjic-1157	122	12	areas	area	NOUN
hjic-1157	122	13	at	at	ADP
hjic-1157	122	14	0.5	0.5	NUM
hjic-1157	122	15	,	,	PUNCT
hjic-1157	122	16	1.0	1.0	NUM
hjic-1157	122	17	and	and	CCONJ
hjic-1157	122	18	1.5	1.5	NUM
hjic-1157	122	19	hours	hour	NOUN
hjic-1157	122	20	(	(	PUNCT
hjic-1157	122	21	fig	fig	NOUN
hjic-1157	122	22	.	.	PUNCT
hjic-1157	123	1	6	6	NUM
hjic-1157	123	2	)	)	PUNCT
hjic-1157	123	3	.	.	PUNCT
hjic-1157	124	1	changes	change	NOUN
hjic-1157	124	2	in	in	ADP
hjic-1157	124	3	the	the	DET
hjic-1157	124	4	enantiomeric	enantiomeric	ADJ
hjic-1157	124	5	ratio	ratio	NOUN
hjic-1157	124	6	as	as	SCONJ
hjic-1157	124	7	the	the	DET
hjic-1157	124	8	reaction	reaction	NOUN
hjic-1157	124	9	progressed	progress	VERB
hjic-1157	124	10	were	be	AUX
hjic-1157	124	11	insignificant	insignificant	ADJ
hjic-1157	124	12	,	,	PUNCT
hjic-1157	124	13	moreover	moreover	ADV
hjic-1157	124	14	,	,	PUNCT
hjic-1157	124	15	the	the	DET
hjic-1157	124	16	difference	difference	NOUN
hjic-1157	124	17	in	in	ADP
hjic-1157	124	18	the	the	DET
hjic-1157	124	19	reaction	reaction	NOUN
hjic-1157	124	20	time	time	NOUN
hjic-1157	124	21	between	between	ADP
hjic-1157	124	22	0.345	0.345	NUM
hjic-1157	124	23	m	m	NOUN
hjic-1157	124	24	and	and	CCONJ
hjic-1157	124	25	0.746	0.746	NUM
hjic-1157	124	26	m	m	NOUN
hjic-1157	124	27	was	be	AUX
hjic-1157	124	28	negligible	negligible	ADJ
hjic-1157	124	29	.	.	PUNCT
hjic-1157	125	1	at	at	ADP
hjic-1157	125	2	0.267	0.267	NUM
hjic-1157	125	3	m	m	NOUN
hjic-1157	125	4	,	,	PUNCT
hjic-1157	125	5	the	the	DET
hjic-1157	125	6	final	final	ADJ
hjic-1157	125	7	result	result	NOUN
hjic-1157	125	8	was	be	AUX
hjic-1157	125	9	0.62	0.62	NUM
hjic-1157	125	10	,	,	PUNCT
hjic-1157	125	11	while	while	SCONJ
hjic-1157	125	12	the	the	DET
hjic-1157	125	13	best	good	ADJ
hjic-1157	125	14	result	result	NOUN
hjic-1157	125	15	,	,	PUNCT
hjic-1157	125	16	that	that	ADV
hjic-1157	125	17	is	is	ADV
hjic-1157	125	18	,	,	PUNCT
hjic-1157	125	19	0.68	0.68	NUM
hjic-1157	125	20	,	,	PUNCT
hjic-1157	125	21	was	be	AUX
hjic-1157	125	22	achieved	achieve	VERB
hjic-1157	125	23	at	at	ADP
hjic-1157	125	24	0.746	0.746	NUM
hjic-1157	125	25	m.	m.	NOUN
hjic-1157	125	26	as	as	ADP
hjic-1157	125	27	a	a	DET
hjic-1157	125	28	result	result	NOUN
hjic-1157	125	29	,	,	PUNCT
hjic-1157	125	30	figure	figure	VERB
hjic-1157	125	31	6	6	NUM
hjic-1157	125	32	:	:	PUNCT
hjic-1157	125	33	the	the	DET
hjic-1157	125	34	enantioselectivity	enantioselectivity	NOUN
hjic-1157	125	35	of	of	ADP
hjic-1157	125	36	the	the	DET
hjic-1157	125	37	wholecellbiocatalyst	wholecellbiocatalyst	NOUN
hjic-1157	125	38	it	it	PRON
hjic-1157	125	39	could	could	AUX
hjic-1157	125	40	be	be	AUX
hjic-1157	125	41	established	establish	VERB
hjic-1157	125	42	that	that	PRON
hjic-1157	125	43	to	to	PART
hjic-1157	125	44	achieve	achieve	VERB
hjic-1157	125	45	an	an	DET
hjic-1157	125	46	optimal	optimal	ADJ
hjic-1157	125	47	reaction	reaction	NOUN
hjic-1157	125	48	rate	rate	NOUN
hjic-1157	125	49	and	and	CCONJ
hjic-1157	125	50	enantioselectivity	enantioselectivity	NOUN
hjic-1157	125	51	,	,	PUNCT
hjic-1157	125	52	different	different	ADJ
hjic-1157	125	53	initial	initial	ADJ
hjic-1157	125	54	substrate	substrate	NOUN
hjic-1157	125	55	concentrations	concentration	NOUN
hjic-1157	125	56	are	be	AUX
hjic-1157	125	57	required	require	VERB
hjic-1157	125	58	.	.	PUNCT
hjic-1157	126	1	in	in	ADP
hjic-1157	126	2	the	the	DET
hjic-1157	126	3	case	case	NOUN
hjic-1157	126	4	of	of	ADP
hjic-1157	126	5	the	the	DET
hjic-1157	126	6	isolated	isolated	ADJ
hjic-1157	126	7	enzyme	enzyme	NOUN
hjic-1157	126	8	,	,	PUNCT
hjic-1157	126	9	the	the	DET
hjic-1157	126	10	enantioselectivity	enantioselectivity	NOUN
hjic-1157	126	11	was	be	AUX
hjic-1157	126	12	measured	measure	VERB
hjic-1157	126	13	at	at	ADP
hjic-1157	126	14	the	the	DET
hjic-1157	126	15	same	same	ADJ
hjic-1157	126	16	substrate	substrate	NOUN
hjic-1157	126	17	concentrations	concentration	NOUN
hjic-1157	126	18	as	as	ADP
hjic-1157	126	19	when	when	SCONJ
hjic-1157	126	20	the	the	DET
hjic-1157	126	21	whole	whole	ADJ
hjic-1157	126	22	-	-	PUNCT
hjic-1157	126	23	cell	cell	NOUN
hjic-1157	126	24	biocatalyst	biocatalyst	NOUN
hjic-1157	126	25	was	be	AUX
hjic-1157	126	26	applied	apply	VERB
hjic-1157	126	27	.	.	PUNCT
hjic-1157	127	1	however	however	ADV
hjic-1157	127	2	,	,	PUNCT
hjic-1157	127	3	since	since	SCONJ
hjic-1157	127	4	only	only	ADV
hjic-1157	127	5	one	one	NUM
hjic-1157	127	6	peak	peak	NOUN
hjic-1157	127	7	corresponding	correspond	VERB
hjic-1157	127	8	to	to	ADP
hjic-1157	127	9	the	the	DET
hjic-1157	127	10	(	(	PUNCT
hjic-1157	127	11	s)-enantiomer	s)-enantiomer	NOUN
hjic-1157	127	12	of	of	ADP
hjic-1157	127	13	the	the	DET
hjic-1157	127	14	derivative	derivative	NOUN
hjic-1157	127	15	was	be	AUX
hjic-1157	127	16	detected	detect	VERB
hjic-1157	127	17	,	,	PUNCT
hjic-1157	127	18	further	further	ADJ
hjic-1157	127	19	analysis	analysis	NOUN
hjic-1157	127	20	was	be	AUX
hjic-1157	127	21	unnecessary	unnecessary	ADJ
hjic-1157	127	22	and	and	CCONJ
hjic-1157	127	23	the	the	DET
hjic-1157	127	24	enantioselectivity	enantioselectivity	NOUN
hjic-1157	127	25	regarded	regard	VERB
hjic-1157	127	26	as	as	ADP
hjic-1157	127	27	100	100	NUM
hjic-1157	127	28	%	%	NOUN
hjic-1157	127	29	.	.	PUNCT
hjic-1157	128	1	as	as	ADP
hjic-1157	128	2	in	in	ADP
hjic-1157	128	3	terms	term	NOUN
hjic-1157	128	4	of	of	ADP
hjic-1157	128	5	consumption	consumption	NOUN
hjic-1157	128	6	optical	optical	ADJ
hjic-1157	128	7	purity	purity	NOUN
hjic-1157	128	8	is	be	AUX
hjic-1157	128	9	a	a	DET
hjic-1157	128	10	key	key	ADJ
hjic-1157	128	11	concern	concern	NOUN
hjic-1157	128	12	,	,	PUNCT
hjic-1157	128	13	the	the	DET
hjic-1157	128	14	results	result	NOUN
hjic-1157	128	15	of	of	ADP
hjic-1157	128	16	this	this	DET
hjic-1157	128	17	work	work	NOUN
hjic-1157	128	18	were	be	AUX
hjic-1157	128	19	compared	compare	VERB
hjic-1157	128	20	with	with	ADP
hjic-1157	128	21	some	some	DET
hjic-1157	128	22	data	datum	NOUN
hjic-1157	128	23	from	from	ADP
hjic-1157	128	24	the	the	DET
hjic-1157	128	25	literature	literature	NOUN
hjic-1157	128	26	(	(	PUNCT
hjic-1157	128	27	table	table	NOUN
hjic-1157	128	28	3	3	NUM
hjic-1157	128	29	)	)	PUNCT
hjic-1157	128	30	.	.	PUNCT
hjic-1157	129	1	in	in	ADP
hjic-1157	129	2	the	the	DET
hjic-1157	129	3	case	case	NOUN
hjic-1157	129	4	of	of	ADP
hjic-1157	129	5	whole	whole	ADJ
hjic-1157	129	6	-	-	PUNCT
hjic-1157	129	7	cell	cell	NOUN
hjic-1157	129	8	biocatalysts	biocatalyst	NOUN
hjic-1157	129	9	,	,	PUNCT
hjic-1157	129	10	the	the	DET
hjic-1157	129	11	results	result	NOUN
hjic-1157	129	12	of	of	ADP
hjic-1157	129	13	rapp	rapp	PROPN
hjic-1157	129	14	et	et	PROPN
hjic-1157	129	15	al	al	PROPN
hjic-1157	129	16	.	.	PUNCT
hjic-1157	130	1	[	[	X
hjic-1157	130	2	16	16	NUM
hjic-1157	130	3	]	]	PUNCT
hjic-1157	130	4	are	be	AUX
hjic-1157	130	5	more	more	ADV
hjic-1157	130	6	favourable	favourable	ADJ
hjic-1157	130	7	than	than	ADP
hjic-1157	130	8	ours	our	NOUN
hjic-1157	130	9	.	.	PUNCT
hjic-1157	131	1	however	however	ADV
hjic-1157	131	2	,	,	PUNCT
hjic-1157	131	3	since	since	SCONJ
hjic-1157	131	4	both	both	DET
hjic-1157	131	5	studies	study	NOUN
hjic-1157	131	6	suggest	suggest	VERB
hjic-1157	131	7	that	that	SCONJ
hjic-1157	131	8	the	the	DET
hjic-1157	131	9	maximum	maximum	ADJ
hjic-1157	131	10	degree	degree	NOUN
hjic-1157	131	11	of	of	ADP
hjic-1157	131	12	conversion	conversion	NOUN
hjic-1157	131	13	and	and	CCONJ
hjic-1157	131	14	enantiomeric	enantiomeric	ADJ
hjic-1157	131	15	excess	excess	NOUN
hjic-1157	131	16	can	can	AUX
hjic-1157	131	17	not	not	PART
hjic-1157	131	18	be	be	AUX
hjic-1157	131	19	achieved	achieve	VERB
hjic-1157	131	20	simultaneously	simultaneously	ADV
hjic-1157	131	21	,	,	PUNCT
hjic-1157	131	22	a	a	DET
hjic-1157	131	23	compromise	compromise	NOUN
hjic-1157	131	24	must	must	AUX
hjic-1157	131	25	be	be	AUX
hjic-1157	131	26	made	make	VERB
hjic-1157	131	27	.	.	PUNCT
hjic-1157	132	1	in	in	ADP
hjic-1157	132	2	the	the	DET
hjic-1157	132	3	case	case	NOUN
hjic-1157	132	4	of	of	ADP
hjic-1157	132	5	the	the	DET
hjic-1157	132	6	isolated	isolated	ADJ
hjic-1157	132	7	enzyme	enzyme	NOUN
hjic-1157	132	8	,	,	PUNCT
hjic-1157	132	9	the	the	DET
hjic-1157	132	10	degree	degree	NOUN
hjic-1157	132	11	of	of	ADP
hjic-1157	132	12	conversion	conversion	NOUN
hjic-1157	132	13	in	in	ADP
hjic-1157	132	14	this	this	DET
hjic-1157	132	15	study	study	NOUN
hjic-1157	132	16	is	be	AUX
hjic-1157	132	17	promising	promise	VERB
hjic-1157	132	18	if	if	SCONJ
hjic-1157	132	19	the	the	DET
hjic-1157	132	20	reaction	reaction	NOUN
hjic-1157	132	21	time	time	NOUN
hjic-1157	132	22	is	be	AUX
hjic-1157	132	23	also	also	ADV
hjic-1157	132	24	taken	take	VERB
hjic-1157	132	25	into	into	ADP
hjic-1157	132	26	account	account	NOUN
hjic-1157	132	27	.	.	PUNCT
hjic-1157	133	1	as	as	ADP
hjic-1157	133	2	for	for	ADP
hjic-1157	133	3	the	the	DET
hjic-1157	133	4	enantiomeric	enantiomeric	ADJ
hjic-1157	133	5	excess	excess	NOUN
hjic-1157	133	6	,	,	PUNCT
hjic-1157	133	7	our	our	PRON
hjic-1157	133	8	result	result	NOUN
hjic-1157	133	9	is	be	AUX
hjic-1157	133	10	clearly	clearly	ADV
hjic-1157	133	11	outstanding	outstanding	ADJ
hjic-1157	133	12	,	,	PUNCT
hjic-1157	133	13	therefore	therefore	ADV
hjic-1157	133	14	,	,	PUNCT
hjic-1157	133	15	recombinant	recombinant	ADJ
hjic-1157	133	16	horse	horse	NOUN
hjic-1157	133	17	-	-	PUNCT
hjic-1157	133	18	liver	liver	NOUN
hjic-1157	133	19	adh	adh	NOUN
hjic-1157	133	20	provides	provide	VERB
hjic-1157	133	21	a	a	DET
hjic-1157	133	22	satisfactory	satisfactory	ADJ
hjic-1157	133	23	alternative	alternative	NOUN
hjic-1157	133	24	for	for	ADP
hjic-1157	133	25	catalysing	catalyse	VERB
hjic-1157	133	26	the	the	DET
hjic-1157	133	27	production	production	NOUN
hjic-1157	133	28	of	of	ADP
hjic-1157	133	29	(	(	PUNCT
hjic-1157	133	30	s)-2phenyl-1	s)-2phenyl-1	NOUN
hjic-1157	133	31	-	-	ADJ
hjic-1157	133	32	propanol	propanol	ADJ
hjic-1157	133	33	.	.	PUNCT
hjic-1157	134	1	4	4	X
hjic-1157	134	2	.	.	X
hjic-1157	134	3	conclusion	conclusion	NOUN
hjic-1157	134	4	in	in	ADP
hjic-1157	134	5	this	this	DET
hjic-1157	134	6	work	work	NOUN
hjic-1157	134	7	,	,	PUNCT
hjic-1157	134	8	the	the	DET
hjic-1157	134	9	conversion	conversion	NOUN
hjic-1157	134	10	of	of	ADP
hjic-1157	134	11	racemic	racemic	ADJ
hjic-1157	134	12	2phenylpropionaldehyde	2phenylpropionaldehyde	NUM
hjic-1157	134	13	into	into	ADP
hjic-1157	134	14	(	(	PUNCT
hjic-1157	134	15	s)-2	s)-2	ADV
hjic-1157	134	16	-	-	PUNCT
hjic-1157	134	17	phenyl-1	phenyl-1	NOUN
hjic-1157	134	18	-	-	PUNCT
hjic-1157	134	19	propanol	propanol	NOUN
hjic-1157	134	20	was	be	AUX
hjic-1157	134	21	investigated	investigate	VERB
hjic-1157	134	22	by	by	ADP
hjic-1157	134	23	applying	apply	VERB
hjic-1157	134	24	a	a	DET
hjic-1157	134	25	whole	whole	ADJ
hjic-1157	134	26	-	-	PUNCT
hjic-1157	134	27	cell	cell	NOUN
hjic-1157	134	28	biocatalyst	biocatalyst	NOUN
hjic-1157	134	29	(	(	PUNCT
hjic-1157	134	30	saccharomyces	saccharomyce	NOUN
hjic-1157	134	31	cerevisiae	cerevisiae	NOUN
hjic-1157	134	32	)	)	PUNCT
hjic-1157	134	33	and	and	CCONJ
hjic-1157	134	34	an	an	DET
hjic-1157	134	35	isolated	isolated	ADJ
hjic-1157	134	36	enzyme	enzyme	NOUN
hjic-1157	134	37	(	(	PUNCT
hjic-1157	134	38	recombinant	recombinant	ADJ
hjic-1157	134	39	horse	horse	NOUN
hjic-1157	134	40	-	-	PUNCT
hjic-1157	134	41	liver	liver	NOUN
hjic-1157	134	42	adh	adh	NOUN
hjic-1157	134	43	expressed	express	VERB
hjic-1157	134	44	in	in	ADP
hjic-1157	134	45	e.	e.	PROPN
hjic-1157	134	46	coli	coli	PROPN
hjic-1157	134	47	)	)	PUNCT
hjic-1157	134	48	.	.	PUNCT
hjic-1157	135	1	significant	significant	ADJ
hjic-1157	135	2	differences	difference	NOUN
hjic-1157	135	3	were	be	AUX
hjic-1157	135	4	observed	observe	VERB
hjic-1157	135	5	between	between	ADP
hjic-1157	135	6	the	the	DET
hjic-1157	135	7	catalysts	catalyst	NOUN
hjic-1157	135	8	in	in	ADP
hjic-1157	135	9	terms	term	NOUN
hjic-1157	135	10	of	of	ADP
hjic-1157	135	11	all	all	DET
hjic-1157	135	12	the	the	DET
hjic-1157	135	13	considered	consider	VERB
hjic-1157	135	14	parameters	parameter	NOUN
hjic-1157	135	15	.	.	PUNCT
hjic-1157	136	1	firstly	firstly	ADV
hjic-1157	136	2	,	,	PUNCT
hjic-1157	136	3	the	the	DET
hjic-1157	136	4	whole	whole	ADJ
hjic-1157	136	5	-	-	PUNCT
hjic-1157	136	6	cell	cell	NOUN
hjic-1157	136	7	biocatalyst	biocatalyst	NOUN
hjic-1157	136	8	exhibited	exhibit	VERB
hjic-1157	136	9	substrate	substrate	NOUN
hjic-1157	136	10	-	-	PUNCT
hjic-1157	136	11	limited	limit	VERB
hjic-1157	136	12	kinetics	kinetic	NOUN
hjic-1157	136	13	,	,	PUNCT
hjic-1157	136	14	while	while	SCONJ
hjic-1157	136	15	the	the	DET
hjic-1157	136	16	isolated	isolated	ADJ
hjic-1157	136	17	enzyme	enzyme	NOUN
hjic-1157	136	18	could	could	AUX
hjic-1157	136	19	be	be	AUX
hjic-1157	136	20	described	describe	VERB
hjic-1157	136	21	by	by	ADP
hjic-1157	136	22	biphasic	biphasic	ADJ
hjic-1157	136	23	kinetics	kinetic	NOUN
hjic-1157	136	24	.	.	PUNCT
hjic-1157	137	1	the	the	DET
hjic-1157	137	2	yeast	yeast	NOUN
hjic-1157	137	3	cell	cell	NOUN
hjic-1157	137	4	contained	contain	VERB
hjic-1157	137	5	a	a	DET
hjic-1157	137	6	sufficient	sufficient	ADJ
hjic-1157	137	7	amount	amount	NOUN
hjic-1157	137	8	of	of	ADP
hjic-1157	137	9	cofactor	cofactor	NOUN
hjic-1157	137	10	for	for	ADP
hjic-1157	137	11	the	the	DET
hjic-1157	137	12	reaction	reaction	NOUN
hjic-1157	137	13	,	,	PUNCT
hjic-1157	137	14	moreover	moreover	ADV
hjic-1157	137	15	,	,	PUNCT
hjic-1157	137	16	its	its	PRON
hjic-1157	137	17	regeneration	regeneration	NOUN
hjic-1157	137	18	was	be	AUX
hjic-1157	137	19	twice	twice	ADV
hjic-1157	137	20	as	as	ADV
hjic-1157	137	21	fast	fast	ADV
hjic-1157	137	22	as	as	ADP
hjic-1157	137	23	in	in	ADP
hjic-1157	137	24	the	the	DET
hjic-1157	137	25	case	case	NOUN
hjic-1157	137	26	of	of	ADP
hjic-1157	137	27	the	the	DET
hjic-1157	137	28	isolated	isolated	ADJ
hjic-1157	137	29	50	50	NUM
hjic-1157	137	30	pp	pp	NOUN
hjic-1157	137	31	.	.	PUNCT
hjic-1157	138	1	23–28	23–28	NUM
hjic-1157	138	2	(	(	PUNCT
hjic-1157	138	3	2022	2022	NUM
hjic-1157	138	4	)	)	PUNCT
hjic-1157	138	5	28	28	NUM
hjic-1157	138	6	lajtai	lajtai	NOUN
hjic-1157	138	7	-	-	PUNCT
hjic-1157	138	8	szabó	szabó	NOUN
hjic-1157	138	9	,	,	PUNCT
hjic-1157	138	10	bagó	bagó	PROPN
hjic-1157	138	11	and	and	CCONJ
hjic-1157	138	12	nemestóthy	nemestóthy	ADJ
hjic-1157	138	13	enzyme	enzyme	NOUN
hjic-1157	138	14	.	.	PUNCT
hjic-1157	139	1	therefore	therefore	ADV
hjic-1157	139	2	,	,	PUNCT
hjic-1157	139	3	the	the	DET
hjic-1157	139	4	whole	whole	ADJ
hjic-1157	139	5	-	-	PUNCT
hjic-1157	139	6	cell	cell	NOUN
hjic-1157	139	7	biocatalyst	biocatalyst	NOUN
hjic-1157	139	8	is	be	AUX
hjic-1157	139	9	more	more	ADV
hjic-1157	139	10	beneficial	beneficial	ADJ
hjic-1157	139	11	from	from	ADP
hjic-1157	139	12	this	this	DET
hjic-1157	139	13	point	point	NOUN
hjic-1157	139	14	of	of	ADP
hjic-1157	139	15	view	view	NOUN
hjic-1157	139	16	.	.	PUNCT
hjic-1157	140	1	on	on	ADP
hjic-1157	140	2	the	the	DET
hjic-1157	140	3	other	other	ADJ
hjic-1157	140	4	hand	hand	NOUN
hjic-1157	140	5	,	,	PUNCT
hjic-1157	140	6	the	the	DET
hjic-1157	140	7	enzymatic	enzymatic	ADJ
hjic-1157	140	8	activity	activity	NOUN
hjic-1157	140	9	of	of	ADP
hjic-1157	140	10	the	the	DET
hjic-1157	140	11	whole	whole	ADJ
hjic-1157	140	12	process	process	NOUN
hjic-1157	140	13	was	be	AUX
hjic-1157	140	14	at	at	ADV
hjic-1157	140	15	least	least	ADV
hjic-1157	140	16	35	35	NUM
hjic-1157	140	17	times	time	NOUN
hjic-1157	140	18	higher	high	ADJ
hjic-1157	140	19	when	when	SCONJ
hjic-1157	140	20	recombinant	recombinant	ADJ
hjic-1157	140	21	horse	horse	NOUN
hjic-1157	140	22	-	-	PUNCT
hjic-1157	140	23	liver	liver	NOUN
hjic-1157	140	24	adh	adh	NOUN
hjic-1157	140	25	was	be	AUX
hjic-1157	140	26	applied	apply	VERB
hjic-1157	140	27	and	and	CCONJ
hjic-1157	140	28	could	could	AUX
hjic-1157	140	29	be	be	AUX
hjic-1157	140	30	further	far	ADV
hjic-1157	140	31	enhanced	enhance	VERB
hjic-1157	140	32	by	by	ADP
hjic-1157	140	33	increasing	increase	VERB
hjic-1157	140	34	the	the	DET
hjic-1157	140	35	initial	initial	ADJ
hjic-1157	140	36	substrate	substrate	NOUN
hjic-1157	140	37	concentration	concentration	NOUN
hjic-1157	140	38	.	.	PUNCT
hjic-1157	141	1	most	most	ADV
hjic-1157	141	2	importantly	importantly	ADV
hjic-1157	141	3	,	,	PUNCT
hjic-1157	141	4	the	the	DET
hjic-1157	141	5	isolated	isolated	ADJ
hjic-1157	141	6	enzyme	enzyme	NOUN
hjic-1157	141	7	catalysed	catalyse	VERB
hjic-1157	141	8	the	the	DET
hjic-1157	141	9	conversion	conversion	NOUN
hjic-1157	141	10	with	with	ADP
hjic-1157	141	11	100	100	NUM
hjic-1157	141	12	%	%	NOUN
hjic-1157	141	13	enantioselectivity	enantioselectivity	NOUN
hjic-1157	141	14	,	,	PUNCT
hjic-1157	141	15	which	which	PRON
hjic-1157	141	16	is	be	AUX
hjic-1157	141	17	also	also	ADV
hjic-1157	141	18	clearly	clearly	ADV
hjic-1157	141	19	outstanding	outstanding	ADJ
hjic-1157	141	20	compared	compare	VERB
hjic-1157	141	21	to	to	ADP
hjic-1157	141	22	data	datum	NOUN
hjic-1157	141	23	from	from	ADP
hjic-1157	141	24	the	the	DET
hjic-1157	141	25	literature	literature	NOUN
hjic-1157	141	26	.	.	PUNCT
hjic-1157	142	1	in	in	ADP
hjic-1157	142	2	conclusion	conclusion	NOUN
hjic-1157	142	3	,	,	PUNCT
hjic-1157	142	4	although	although	SCONJ
hjic-1157	142	5	recombinant	recombinant	ADJ
hjic-1157	142	6	horse	horse	NOUN
hjic-1157	142	7	-	-	PUNCT
hjic-1157	142	8	liver	liver	NOUN
hjic-1157	142	9	adh	adh	NOUN
hjic-1157	142	10	is	be	AUX
hjic-1157	142	11	more	more	ADV
hjic-1157	142	12	expensive	expensive	ADJ
hjic-1157	142	13	,	,	PUNCT
hjic-1157	142	14	it	it	PRON
hjic-1157	142	15	is	be	AUX
hjic-1157	142	16	definitely	definitely	ADV
hjic-1157	142	17	a	a	DET
hjic-1157	142	18	more	more	ADV
hjic-1157	142	19	efficient	efficient	ADJ
hjic-1157	142	20	catalyst	catalyst	NOUN
hjic-1157	142	21	than	than	ADP
hjic-1157	142	22	yeast	yeast	NOUN
hjic-1157	142	23	as	as	ADP
hjic-1157	142	24	a	a	DET
hjic-1157	142	25	whole	whole	ADJ
hjic-1157	142	26	-	-	PUNCT
hjic-1157	142	27	cell	cell	NOUN
hjic-1157	142	28	biocatalyst	biocatalyst	NOUN
hjic-1157	142	29	.	.	PUNCT
hjic-1157	143	1	therefore	therefore	ADV
hjic-1157	143	2	,	,	PUNCT
hjic-1157	143	3	recombinant	recombinant	ADJ
hjic-1157	143	4	horse	horse	NOUN
hjic-1157	143	5	-	-	PUNCT
hjic-1157	143	6	liver	liver	NOUN
hjic-1157	143	7	adh	adh	NOUN
hjic-1157	143	8	is	be	AUX
hjic-1157	143	9	a	a	DET
hjic-1157	143	10	promising	promising	ADJ
hjic-1157	143	11	biocatalyst	biocatalyst	NOUN
hjic-1157	143	12	with	with	ADP
hjic-1157	143	13	regard	regard	NOUN
hjic-1157	143	14	to	to	ADP
hjic-1157	143	15	the	the	DET
hjic-1157	143	16	synthesis	synthesis	NOUN
hjic-1157	143	17	of	of	ADP
hjic-1157	143	18	(	(	PUNCT
hjic-1157	143	19	s)-2	s)-2	NOUN
hjic-1157	143	20	-	-	PUNCT
hjic-1157	143	21	phenyl-1	phenyl-1	NOUN
hjic-1157	143	22	-	-	PUNCT
hjic-1157	143	23	propanol	propanol	NOUN
hjic-1157	143	24	.	.	PUNCT
hjic-1157	144	1	acknowledgement	acknowledgement	NOUN
hjic-1157	144	2	this	this	DET
hjic-1157	144	3	research	research	NOUN
hjic-1157	144	4	was	be	AUX
hjic-1157	144	5	supported	support	VERB
hjic-1157	144	6	by	by	ADP
hjic-1157	144	7	the	the	DET
hjic-1157	144	8	ministry	ministry	PROPN
hjic-1157	144	9	for	for	ADP
hjic-1157	144	10	innovation	innovation	NOUN
hjic-1157	144	11	and	and	CCONJ
hjic-1157	144	12	technology	technology	NOUN
hjic-1157	144	13	;	;	PUNCT
hjic-1157	144	14	the	the	DET
hjic-1157	144	15	national	national	ADJ
hjic-1157	144	16	research	research	NOUN
hjic-1157	144	17	,	,	PUNCT
hjic-1157	144	18	development	development	NOUN
hjic-1157	144	19	and	and	CCONJ
hjic-1157	144	20	innovation	innovation	NOUN
hjic-1157	144	21	office	office	NOUN
hjic-1157	144	22	and	and	CCONJ
hjic-1157	144	23	the	the	DET
hjic-1157	144	24	new	new	ADJ
hjic-1157	144	25	national	national	PROPN
hjic-1157	144	26	excellence	excellence	PROPN
hjic-1157	144	27	programme	programme	PROPN
hjic-1157	144	28	.	.	PUNCT
hjic-1157	145	1	this	this	DET
hjic-1157	145	2	study	study	NOUN
hjic-1157	145	3	was	be	AUX
hjic-1157	145	4	financed	finance	VERB
hjic-1157	145	5	by	by	ADP
hjic-1157	145	6	the	the	DET
hjic-1157	145	7	national	national	PROPN
hjic-1157	145	8	laboratory	laboratory	NOUN
hjic-1157	145	9	for	for	ADP
hjic-1157	145	10	climate	climate	NOUN
hjic-1157	145	11	change	change	NOUN
hjic-1157	145	12	(	(	PUNCT
hjic-1157	145	13	hungary	hungary	NOUN
hjic-1157	145	14	)	)	PUNCT
hjic-1157	145	15	project	project	NOUN
hjic-1157	145	16	number	number	NOUN
hjic-1157	145	17	nkfih471	nkfih471	PROPN
hjic-1157	145	18	-	-	PUNCT
hjic-1157	145	19	3/2021	3/2021	PROPN
hjic-1157	145	20	.	.	PUNCT
hjic-1157	146	1	references	reference	NOUN
hjic-1157	146	2	[	[	X
hjic-1157	146	3	1	1	NUM
hjic-1157	146	4	]	]	PUNCT
hjic-1157	146	5	scognamiglio	scognamiglio	NOUN
hjic-1157	146	6	,	,	PUNCT
hjic-1157	146	7	j.	j.	PROPN
hjic-1157	146	8	;	;	PUNCT
hjic-1157	146	9	jones	jones	PROPN
hjic-1157	146	10	,	,	PUNCT
hjic-1157	146	11	l.	l.	PROPN
hjic-1157	146	12	;	;	PUNCT
hjic-1157	146	13	letizia	letizia	PROPN
hjic-1157	146	14	,	,	PUNCT
hjic-1157	146	15	c.	c.	PROPN
hjic-1157	146	16	s.	s.	PROPN
hjic-1157	146	17	;	;	PUNCT
hjic-1157	146	18	api	api	NOUN
hjic-1157	146	19	,	,	PUNCT
hjic-1157	146	20	a.	a.	NOUN
hjic-1157	146	21	m.	m.	NOUN
hjic-1157	146	22	:	:	PUNCT
hjic-1157	146	23	fragrance	fragrance	NOUN
hjic-1157	146	24	material	material	NOUN
hjic-1157	146	25	review	review	NOUN
hjic-1157	146	26	on	on	ADP
hjic-1157	146	27	βmethylphenethyl	βmethylphenethyl	PROPN
hjic-1157	146	28	alcohol	alcohol	PROPN
hjic-1157	146	29	,	,	PUNCT
hjic-1157	146	30	food	food	NOUN
hjic-1157	146	31	chem	chem	NOUN
hjic-1157	146	32	.	.	PUNCT
hjic-1157	147	1	toxicol	toxicol	PROPN
hjic-1157	147	2	.	.	PUNCT
hjic-1157	147	3	,	,	PUNCT
hjic-1157	147	4	2012	2012	NUM
hjic-1157	147	5	,	,	PUNCT
hjic-1157	147	6	50(2	50(2	NUM
hjic-1157	147	7	)	)	PUNCT
hjic-1157	147	8	,	,	PUNCT
hjic-1157	147	9	199–203	199–203	NUM
hjic-1157	147	10	doi	doi	NOUN
hjic-1157	147	11	:	:	PUNCT
hjic-1157	147	12	10.1016	10.1016	NUM
hjic-1157	147	13	/	/	SYM
hjic-1157	147	14	j.fct.2011.10.023	j.fct.2011.10.023	PROPN
hjic-1157	148	1	[	[	X
hjic-1157	148	2	2	2	NUM
hjic-1157	148	3	]	]	X
hjic-1157	148	4	rapp	rapp	X
hjic-1157	148	5	,	,	PUNCT
hjic-1157	148	6	c.	c.	NOUN
hjic-1157	148	7	;	;	PUNCT
hjic-1157	148	8	pival	pival	NOUN
hjic-1157	148	9	-	-	PUNCT
hjic-1157	148	10	marko	marko	PROPN
hjic-1157	148	11	,	,	PUNCT
hjic-1157	148	12	s.	s.	PROPN
hjic-1157	148	13	;	;	PUNCT
hjic-1157	148	14	tassano	tassano	PROPN
hjic-1157	148	15	,	,	PUNCT
hjic-1157	148	16	e.	e.	PROPN
hjic-1157	148	17	;	;	PUNCT
hjic-1157	148	18	nidetzky	nidetzky	PROPN
hjic-1157	148	19	,	,	PUNCT
hjic-1157	148	20	b.	b.	PROPN
hjic-1157	148	21	;	;	PUNCT
hjic-1157	148	22	kratzer	kratzer	PROPN
hjic-1157	148	23	,	,	PUNCT
hjic-1157	148	24	r.	r.	PROPN
hjic-1157	148	25	:	:	PUNCT
hjic-1157	148	26	reductive	reductive	ADJ
hjic-1157	148	27	enzymatic	enzymatic	ADJ
hjic-1157	148	28	dynamic	dynamic	ADJ
hjic-1157	148	29	kinetic	kinetic	NOUN
hjic-1157	148	30	resolution	resolution	NOUN
hjic-1157	148	31	affording	afford	VERB
hjic-1157	148	32	115	115	NUM
hjic-1157	148	33	g	g	NOUN
hjic-1157	148	34	/	/	SYM
hjic-1157	148	35	l	l	NOUN
hjic-1157	148	36	(	(	PUNCT
hjic-1157	148	37	s)-2phenylpropanol	s)-2phenylpropanol	PROPN
hjic-1157	148	38	,	,	PUNCT
hjic-1157	148	39	bmc	bmc	ADJ
hjic-1157	148	40	biotechnol	biotechnol	NOUN
hjic-1157	148	41	.	.	PUNCT
hjic-1157	148	42	,	,	PUNCT
hjic-1157	148	43	2021	2021	NUM
hjic-1157	148	44	,	,	PUNCT
hjic-1157	148	45	21	21	NUM
hjic-1157	148	46	,	,	PUNCT
hjic-1157	148	47	1–13	1–13	NUM
hjic-1157	148	48	,	,	PUNCT
hjic-1157	148	49	doi	doi	NOUN
hjic-1157	148	50	:	:	PUNCT
hjic-1157	148	51	10.1186	10.1186	NUM
hjic-1157	148	52	/	/	SYM
hjic-1157	148	53	s12896	s12896	NOUN
hjic-1157	148	54	-	-	PUNCT
hjic-1157	148	55	021	021	NUM
hjic-1157	148	56	-	-	PUNCT
hjic-1157	148	57	00715	00715	NUM
hjic-1157	148	58	-	-	SYM
hjic-1157	148	59	5	5	NUM
hjic-1157	148	60	[	[	SYM
hjic-1157	148	61	3	3	NUM
hjic-1157	148	62	]	]	PUNCT
hjic-1157	148	63	klebe	klebe	NOUN
hjic-1157	148	64	,	,	PUNCT
hjic-1157	148	65	g.	g.	NOUN
hjic-1157	148	66	:	:	PUNCT
hjic-1157	148	67	optical	optical	ADJ
hjic-1157	148	68	activity	activity	NOUN
hjic-1157	148	69	and	and	CCONJ
hjic-1157	148	70	biological	biological	ADJ
hjic-1157	148	71	effect	effect	NOUN
hjic-1157	148	72	,	,	PUNCT
hjic-1157	148	73	in	in	ADP
hjic-1157	148	74	:	:	PUNCT
hjic-1157	148	75	klebe	klebe	NOUN
hjic-1157	148	76	.	.	PUNCT
hjic-1157	149	1	g	g	NOUN
hjic-1157	149	2	(	(	PUNCT
hjic-1157	149	3	ed	ed	NOUN
hjic-1157	149	4	.	.	PROPN
hjic-1157	149	5	):	):	PUNCT
hjic-1157	149	6	drug	drug	NOUN
hjic-1157	149	7	design	design	NOUN
hjic-1157	149	8	:	:	PUNCT
hjic-1157	149	9	methodology	methodology	NOUN
hjic-1157	149	10	,	,	PUNCT
hjic-1157	149	11	concepts	concept	NOUN
hjic-1157	149	12	,	,	PUNCT
hjic-1157	149	13	and	and	CCONJ
hjic-1157	149	14	mode	mode	NOUN
hjic-1157	149	15	-	-	PUNCT
hjic-1157	149	16	of	of	ADP
hjic-1157	149	17	-	-	PUNCT
hjic-1157	149	18	action	action	NOUN
hjic-1157	149	19	,	,	PUNCT
hjic-1157	149	20	pp	pp	ADJ
hjic-1157	149	21	.	.	PUNCT
hjic-1157	150	1	89–110	89–110	NUM
hjic-1157	150	2	(	(	PUNCT
hjic-1157	150	3	springer	springer	NOUN
hjic-1157	150	4	berlin	berlin	PROPN
hjic-1157	150	5	heidelberg	heidelberg	PROPN
hjic-1157	150	6	;	;	PUNCT
hjic-1157	150	7	berlin	berlin	PROPN
hjic-1157	150	8	,	,	PUNCT
hjic-1157	150	9	heidelberg	heidelberg	PROPN
hjic-1157	150	10	,	,	PUNCT
hjic-1157	150	11	germany	germany	PROPN
hjic-1157	150	12	)	)	PUNCT
hjic-1157	150	13	2013	2013	NUM
hjic-1157	150	14	doi	doi	NOUN
hjic-1157	150	15	:	:	PUNCT
hjic-1157	150	16	10.1007/978	10.1007/978	NUM
hjic-1157	150	17	-	-	SYM
hjic-1157	150	18	3	3	NUM
hjic-1157	150	19	-	-	PUNCT
hjic-1157	150	20	642	642	NUM
hjic-1157	150	21	-	-	PUNCT
hjic-1157	150	22	17907	17907	NUM
hjic-1157	150	23	-	-	SYM
hjic-1157	150	24	5_5	5_5	NUM
hjic-1157	150	25	[	[	SYM
hjic-1157	150	26	4	4	NUM
hjic-1157	150	27	]	]	X
hjic-1157	150	28	lajtai	lajtai	ADJ
hjic-1157	150	29	-	-	PUNCT
hjic-1157	150	30	szabó	szabó	NOUN
hjic-1157	150	31	,	,	PUNCT
hjic-1157	150	32	p.	p.	NOUN
hjic-1157	150	33	;	;	PUNCT
hjic-1157	150	34	nemestóthy	nemestóthy	ADJ
hjic-1157	150	35	,	,	PUNCT
hjic-1157	150	36	n.	n.	NOUN
hjic-1157	150	37	;	;	PUNCT
hjic-1157	150	38	gubicza	gubicza	PROPN
hjic-1157	150	39	,	,	PUNCT
hjic-1157	150	40	l.	l.	PROPN
hjic-1157	150	41	:	:	PUNCT
hjic-1157	150	42	the	the	DET
hjic-1157	150	43	role	role	NOUN
hjic-1157	150	44	of	of	ADP
hjic-1157	150	45	water	water	NOUN
hjic-1157	150	46	activity	activity	NOUN
hjic-1157	150	47	in	in	ADP
hjic-1157	150	48	terms	term	NOUN
hjic-1157	150	49	of	of	ADP
hjic-1157	150	50	enzyme	enzyme	NOUN
hjic-1157	150	51	activity	activity	NOUN
hjic-1157	150	52	and	and	CCONJ
hjic-1157	150	53	enantioselectivity	enantioselectivity	NOUN
hjic-1157	150	54	during	during	ADP
hjic-1157	150	55	enzymatic	enzymatic	ADJ
hjic-1157	150	56	esterification	esterification	NOUN
hjic-1157	150	57	in	in	ADP
hjic-1157	150	58	non	non	ADJ
hjic-1157	150	59	-	-	ADJ
hjic-1157	150	60	conventional	conventional	ADJ
hjic-1157	150	61	media	medium	NOUN
hjic-1157	150	62	,	,	PUNCT
hjic-1157	150	63	hung	hung	PROPN
hjic-1157	150	64	.	.	PUNCT
hjic-1157	151	1	j.	j.	PROPN
hjic-1157	151	2	ind	ind	PROPN
hjic-1157	151	3	.	.	PUNCT
hjic-1157	152	1	chem	chem	PROPN
hjic-1157	152	2	.	.	PUNCT
hjic-1157	152	3	,	,	PUNCT
hjic-1157	152	4	2020	2020	NUM
hjic-1157	152	5	,	,	PUNCT
hjic-1157	152	6	48(2	48(2	NUM
hjic-1157	152	7	)	)	PUNCT
hjic-1157	152	8	,	,	PUNCT
hjic-1157	152	9	9–12	9–12	PROPN
hjic-1157	152	10	doi	doi	NOUN
hjic-1157	152	11	:	:	PUNCT
hjic-1157	152	12	10.33927	10.33927	NUM
hjic-1157	152	13	/	/	SYM
hjic-1157	152	14	hjic-2020	hjic-2020	NOUN
hjic-1157	152	15	-	-	PUNCT
hjic-1157	152	16	22	22	NUM
hjic-1157	153	1	[	[	X
hjic-1157	153	2	5	5	NUM
hjic-1157	153	3	]	]	PUNCT
hjic-1157	153	4	reetz	reetz	ADJ
hjic-1157	153	5	,	,	PUNCT
hjic-1157	153	6	m.	m.	NOUN
hjic-1157	153	7	t.	t.	PROPN
hjic-1157	153	8	:	:	PUNCT
hjic-1157	153	9	controlling	control	VERB
hjic-1157	153	10	the	the	DET
hjic-1157	153	11	enantioselectivity	enantioselectivity	NOUN
hjic-1157	153	12	of	of	ADP
hjic-1157	153	13	enzymes	enzyme	NOUN
hjic-1157	153	14	by	by	ADP
hjic-1157	153	15	directed	direct	VERB
hjic-1157	153	16	evolution	evolution	NOUN
hjic-1157	153	17	:	:	PUNCT
hjic-1157	153	18	practical	practical	ADJ
hjic-1157	153	19	and	and	CCONJ
hjic-1157	153	20	theoretical	theoretical	ADJ
hjic-1157	153	21	ramifications	ramification	NOUN
hjic-1157	153	22	,	,	PUNCT
hjic-1157	153	23	proc	proc	NOUN
hjic-1157	153	24	.	.	PUNCT
hjic-1157	154	1	natl	natl	PROPN
hjic-1157	154	2	.	.	PUNCT
hjic-1157	155	1	acad	acad	PROPN
hjic-1157	155	2	.	.	PUNCT
hjic-1157	156	1	sci	sci	PROPN
hjic-1157	156	2	.	.	PROPN
hjic-1157	156	3	,	,	PUNCT
hjic-1157	156	4	2004	2004	NUM
hjic-1157	156	5	,	,	PUNCT
hjic-1157	156	6	101(16	101(16	NUM
hjic-1157	156	7	)	)	PUNCT
hjic-1157	156	8	,	,	PUNCT
hjic-1157	156	9	5716–5722	5716–5722	NUM
hjic-1157	156	10	doi	doi	NOUN
hjic-1157	156	11	:	:	PUNCT
hjic-1157	156	12	10.1073	10.1073	NUM
hjic-1157	156	13	/	/	SYM
hjic-1157	156	14	pnas	pnas	PROPN
hjic-1157	156	15	.	.	PUNCT
hjic-1157	156	16	0306866101	0306866101	NUM
hjic-1157	157	1	[	[	X
hjic-1157	157	2	6	6	NUM
hjic-1157	157	3	]	]	X
hjic-1157	157	4	silva	silva	PROPN
hjic-1157	157	5	,	,	PUNCT
hjic-1157	157	6	j.	j.	PROPN
hjic-1157	157	7	;	;	PUNCT
hjic-1157	157	8	alarcón	alarcón	PROPN
hjic-1157	157	9	,	,	PUNCT
hjic-1157	157	10	j.	j.	PROPN
hjic-1157	157	11	;	;	PUNCT
hjic-1157	157	12	aguila	aguila	PROPN
hjic-1157	157	13	,	,	PUNCT
hjic-1157	157	14	s.	s.	PROPN
hjic-1157	157	15	a.	a.	PROPN
hjic-1157	157	16	;	;	PUNCT
hjic-1157	157	17	alderete	alderete	PROPN
hjic-1157	157	18	,	,	PUNCT
hjic-1157	157	19	j.	j.	PROPN
hjic-1157	157	20	b.	b.	PROPN
hjic-1157	157	21	:	:	PUNCT
hjic-1157	157	22	bioreduction	bioreduction	NOUN
hjic-1157	157	23	of	of	ADP
hjic-1157	157	24	some	some	DET
hjic-1157	157	25	common	common	ADJ
hjic-1157	157	26	carbonylic	carbonylic	ADJ
hjic-1157	157	27	compounds	compound	NOUN
hjic-1157	157	28	mediated	mediate	VERB
hjic-1157	157	29	by	by	ADP
hjic-1157	157	30	yeasts	yeast	NOUN
hjic-1157	157	31	,	,	PUNCT
hjic-1157	157	32	z.	z.	PROPN
hjic-1157	157	33	naturforsch	naturforsch	PROPN
hjic-1157	157	34	.	.	PUNCT
hjic-1157	157	35	,	,	PUNCT
hjic-1157	158	1	c	c	X
hjic-1157	158	2	,	,	PUNCT
hjic-1157	158	3	2010	2010	NUM
hjic-1157	158	4	,	,	PUNCT
hjic-1157	158	5	65(1	65(1	NOUN
hjic-1157	158	6	-	-	SYM
hjic-1157	158	7	2	2	NUM
hjic-1157	158	8	)	)	PUNCT
hjic-1157	158	9	,	,	PUNCT
hjic-1157	158	10	1–9	1–9	NUM
hjic-1157	158	11	doi	doi	NOUN
hjic-1157	158	12	:	:	PUNCT
hjic-1157	158	13	10.1515	10.1515	NUM
hjic-1157	158	14	/	/	SYM
hjic-1157	158	15	znc-2010	znc-2010	NOUN
hjic-1157	158	16	-	-	PUNCT
hjic-1157	158	17	1	1	NUM
hjic-1157	158	18	-	-	NUM
hjic-1157	158	19	201	201	NUM
hjic-1157	158	20	[	[	X
hjic-1157	158	21	7	7	NUM
hjic-1157	158	22	]	]	PUNCT
hjic-1157	158	23	pscheidt	pscheidt	NOUN
hjic-1157	158	24	,	,	PUNCT
hjic-1157	158	25	b.	b.	PROPN
hjic-1157	158	26	;	;	PUNCT
hjic-1157	158	27	glieder	glieder	NOUN
hjic-1157	158	28	,	,	PUNCT
hjic-1157	158	29	a.	a.	NOUN
hjic-1157	158	30	:	:	PUNCT
hjic-1157	158	31	yeast	yeast	NOUN
hjic-1157	158	32	cell	cell	NOUN
hjic-1157	158	33	factories	factory	NOUN
hjic-1157	158	34	for	for	ADP
hjic-1157	158	35	fine	fine	ADJ
hjic-1157	158	36	chemical	chemical	NOUN
hjic-1157	158	37	and	and	CCONJ
hjic-1157	158	38	api	api	NOUN
hjic-1157	158	39	production	production	NOUN
hjic-1157	158	40	,	,	PUNCT
hjic-1157	158	41	microb	microb	PROPN
hjic-1157	158	42	.	.	PUNCT
hjic-1157	159	1	cell	cell	NOUN
hjic-1157	159	2	fact	fact	NOUN
hjic-1157	159	3	.	.	PUNCT
hjic-1157	159	4	,	,	PUNCT
hjic-1157	159	5	2008	2008	NUM
hjic-1157	159	6	,	,	PUNCT
hjic-1157	159	7	7(1	7(1	NUM
hjic-1157	159	8	)	)	PUNCT
hjic-1157	159	9	,	,	PUNCT
hjic-1157	159	10	25	25	NUM
hjic-1157	159	11	doi	doi	NOUN
hjic-1157	159	12	:	:	PUNCT
hjic-1157	159	13	10.1186/1475	10.1186/1475	NUM
hjic-1157	159	14	-	-	SYM
hjic-1157	159	15	2859	2859	NUM
hjic-1157	159	16	-	-	SYM
hjic-1157	159	17	7	7	NUM
hjic-1157	159	18	-	-	SYM
hjic-1157	159	19	25	25	NUM
hjic-1157	159	20	[	[	NOUN
hjic-1157	159	21	8	8	NUM
hjic-1157	159	22	]	]	PUNCT
hjic-1157	159	23	schallmey	schallmey	NOUN
hjic-1157	159	24	,	,	PUNCT
hjic-1157	159	25	a.	a.	NOUN
hjic-1157	159	26	;	;	PUNCT
hjic-1157	159	27	domínguez	domínguez	PROPN
hjic-1157	159	28	de	de	X
hjic-1157	159	29	maría	maría	PROPN
hjic-1157	159	30	,	,	PUNCT
hjic-1157	159	31	p.	p.	PROPN
hjic-1157	159	32	;	;	PUNCT
hjic-1157	159	33	bracco	bracco	PROPN
hjic-1157	159	34	,	,	PUNCT
hjic-1157	159	35	p.	p.	NOUN
hjic-1157	159	36	:	:	PUNCT
hjic-1157	159	37	biocatalytic	biocatalytic	ADJ
hjic-1157	159	38	asymmetric	asymmetric	ADJ
hjic-1157	159	39	oxidations	oxidation	NOUN
hjic-1157	159	40	in	in	ADP
hjic-1157	159	41	stereoselective	stereoselective	ADJ
hjic-1157	159	42	synthesis	synthesis	NOUN
hjic-1157	159	43	,	,	PUNCT
hjic-1157	159	44	in	in	ADP
hjic-1157	159	45	:	:	PUNCT
hjic-1157	159	46	andrushko	andrushko	PROPN
hjic-1157	159	47	v.	v.	PROPN
hjic-1157	159	48	;	;	PUNCT
hjic-1157	159	49	andrushko	andrushko	PROPN
hjic-1157	159	50	,	,	PUNCT
hjic-1157	159	51	n.	n.	NOUN
hjic-1157	159	52	(	(	PUNCT
hjic-1157	159	53	eds	ed	NOUN
hjic-1157	159	54	.	.	PROPN
hjic-1157	159	55	):	):	PUNCT
hjic-1157	159	56	stereoselective	stereoselective	ADJ
hjic-1157	159	57	synthesis	synthesis	NOUN
hjic-1157	159	58	of	of	ADP
hjic-1157	159	59	drugs	drug	NOUN
hjic-1157	159	60	and	and	CCONJ
hjic-1157	159	61	natural	natural	ADJ
hjic-1157	159	62	products	product	NOUN
hjic-1157	159	63	,	,	PUNCT
hjic-1157	159	64	pp	pp	ADV
hjic-1157	159	65	.	.	PUNCT
hjic-1157	160	1	1089–1114	1089–1114	NUM
hjic-1157	160	2	(	(	PUNCT
hjic-1157	160	3	john	john	PROPN
hjic-1157	160	4	wiley	wiley	PROPN
hjic-1157	160	5	&	&	CCONJ
hjic-1157	160	6	sons	sons	PROPN
hjic-1157	160	7	,	,	PUNCT
hjic-1157	160	8	inc	inc	PROPN
hjic-1157	160	9	.	.	PROPN
hjic-1157	160	10	,	,	PUNCT
hjic-1157	160	11	hoboken	hoboken	PROPN
hjic-1157	160	12	,	,	PUNCT
hjic-1157	160	13	usa	usa	PROPN
hjic-1157	160	14	)	)	PUNCT
hjic-1157	160	15	2013	2013	NUM
hjic-1157	160	16	doi	doi	NOUN
hjic-1157	160	17	:	:	PUNCT
hjic-1157	160	18	10.1002/9781118596784.ssd036	10.1002/9781118596784.ssd036	PROPN
hjic-1157	161	1	[	[	X
hjic-1157	161	2	9	9	NUM
hjic-1157	161	3	]	]	SYM
hjic-1157	161	4	hu	hu	PROPN
hjic-1157	161	5	,	,	PUNCT
hjic-1157	161	6	q.	q.	PROPN
hjic-1157	161	7	;	;	PUNCT
hjic-1157	161	8	xu	xu	PROPN
hjic-1157	161	9	,	,	PUNCT
hjic-1157	161	10	y.	y.	PROPN
hjic-1157	161	11	;	;	PUNCT
hjic-1157	161	12	nie	nie	PROPN
hjic-1157	161	13	,	,	PUNCT
hjic-1157	161	14	y.	y.	NOUN
hjic-1157	161	15	:	:	PUNCT
hjic-1157	161	16	highly	highly	ADV
hjic-1157	161	17	enantioselective	enantioselective	ADJ
hjic-1157	161	18	reduction	reduction	NOUN
hjic-1157	161	19	of	of	ADP
hjic-1157	161	20	2	2	NUM
hjic-1157	161	21	-	-	PUNCT
hjic-1157	161	22	hydroxy-1	hydroxy-1	NOUN
hjic-1157	161	23	-	-	PUNCT
hjic-1157	161	24	phenylethanone	phenylethanone	NOUN
hjic-1157	161	25	to	to	ADP
hjic-1157	161	26	enantiopure	enantiopure	NOUN
hjic-1157	161	27	(	(	PUNCT
hjic-1157	161	28	r)-phenyl-1,2	r)-phenyl-1,2	NOUN
hjic-1157	161	29	-	-	PUNCT
hjic-1157	161	30	ethanediol	ethanediol	NOUN
hjic-1157	161	31	using	use	VERB
hjic-1157	161	32	saccharomyces	saccharomyce	NOUN
hjic-1157	161	33	cerevisiae	cerevisiae	NOUN
hjic-1157	161	34	of	of	ADP
hjic-1157	161	35	remarkable	remarkable	ADJ
hjic-1157	161	36	reaction	reaction	NOUN
hjic-1157	161	37	stability	stability	NOUN
hjic-1157	161	38	,	,	PUNCT
hjic-1157	162	1	bioresour	bioresour	PROPN
hjic-1157	162	2	.	.	PUNCT
hjic-1157	162	3	technol	technol	PROPN
hjic-1157	162	4	.	.	PROPN
hjic-1157	162	5	,	,	PUNCT
hjic-1157	162	6	2010	2010	NUM
hjic-1157	162	7	,	,	PUNCT
hjic-1157	162	8	101(22	101(22	NUM
hjic-1157	162	9	)	)	PUNCT
hjic-1157	162	10	,	,	PUNCT
hjic-1157	162	11	8502	8502	NUM
hjic-1157	162	12	–	–	PUNCT
hjic-1157	162	13	8508	8508	NUM
hjic-1157	162	14	doi	doi	NOUN
hjic-1157	162	15	:	:	PUNCT
hjic-1157	162	16	10.1016	10.1016	NUM
hjic-1157	162	17	/	/	SYM
hjic-1157	162	18	j.biortech.2010.06.044	j.biortech.2010.06.044	X
hjic-1157	163	1	[	[	X
hjic-1157	163	2	10	10	NUM
hjic-1157	163	3	]	]	X
hjic-1157	163	4	díaz	díaz	NOUN
hjic-1157	163	5	-	-	PUNCT
hjic-1157	163	6	rodríguez	rodríguez	NOUN
hjic-1157	163	7	,	,	PUNCT
hjic-1157	163	8	a.	a.	NOUN
hjic-1157	163	9	;	;	PUNCT
hjic-1157	163	10	iglesias	iglesias	PROPN
hjic-1157	163	11	-	-	PUNCT
hjic-1157	163	12	fernández	fernández	PROPN
hjic-1157	163	13	,	,	PUNCT
hjic-1157	163	14	j.	j.	PROPN
hjic-1157	163	15	;	;	PUNCT
hjic-1157	163	16	rovira	rovira	PROPN
hjic-1157	163	17	,	,	PUNCT
hjic-1157	163	18	c.	c.	PROPN
hjic-1157	163	19	;	;	PUNCT
hjic-1157	163	20	gotor	gotor	NOUN
hjic-1157	163	21	-	-	PUNCT
hjic-1157	163	22	fernández	fernández	PROPN
hjic-1157	163	23	,	,	PUNCT
hjic-1157	163	24	v.	v.	ADJ
hjic-1157	163	25	:	:	PUNCT
hjic-1157	163	26	enantioselective	enantioselective	ADJ
hjic-1157	163	27	preparation	preparation	NOUN
hjic-1157	163	28	of	of	ADP
hjic-1157	163	29	δ	δ	PROPN
hjic-1157	163	30	-	-	PUNCT
hjic-1157	163	31	valerolactones	valerolactone	NOUN
hjic-1157	163	32	with	with	ADP
hjic-1157	163	33	horse	horse	NOUN
hjic-1157	163	34	liver	liver	NOUN
hjic-1157	163	35	alcohol	alcohol	NOUN
hjic-1157	163	36	dehydrogenase	dehydrogenase	NOUN
hjic-1157	163	37	,	,	PUNCT
hjic-1157	163	38	chem	chem	NOUN
hjic-1157	163	39	.	.	PUNCT
hjic-1157	163	40	cat	cat	NOUN
hjic-1157	163	41	.	.	PUNCT
hjic-1157	164	1	chem	chem	PROPN
hjic-1157	164	2	.	.	PUNCT
hjic-1157	164	3	,	,	PUNCT
hjic-1157	164	4	2014	2014	NUM
hjic-1157	164	5	,	,	PUNCT
hjic-1157	164	6	6(4	6(4	NUM
hjic-1157	164	7	)	)	PUNCT
hjic-1157	164	8	,	,	PUNCT
hjic-1157	164	9	977	977	NUM
hjic-1157	164	10	–	–	PUNCT
hjic-1157	164	11	980	980	NUM
hjic-1157	164	12	doi	doi	NOUN
hjic-1157	164	13	:	:	PUNCT
hjic-1157	164	14	10.1002	10.1002	NUM
hjic-1157	164	15	/	/	SYM
hjic-1157	165	1	cctc.201300640	cctc.201300640	PROPN
hjic-1157	165	2	[	[	PUNCT
hjic-1157	165	3	11	11	NUM
hjic-1157	165	4	]	]	X
hjic-1157	165	5	kim	kim	PROPN
hjic-1157	165	6	,	,	PUNCT
hjic-1157	165	7	k.	k.	PROPN
hjic-1157	165	8	;	;	PUNCT
hjic-1157	165	9	plapp	plapp	PROPN
hjic-1157	165	10	,	,	PUNCT
hjic-1157	165	11	b.	b.	PROPN
hjic-1157	166	1	v.	v.	NOUN
hjic-1157	166	2	:	:	PUNCT
hjic-1157	166	3	inversion	inversion	NOUN
hjic-1157	166	4	of	of	ADP
hjic-1157	166	5	substrate	substrate	NOUN
hjic-1157	166	6	stereoselectivity	stereoselectivity	NOUN
hjic-1157	166	7	of	of	ADP
hjic-1157	166	8	horse	horse	NOUN
hjic-1157	166	9	liver	liver	NOUN
hjic-1157	166	10	alcohol	alcohol	NOUN
hjic-1157	166	11	dehydrogenase	dehydrogenase	NOUN
hjic-1157	166	12	by	by	ADP
hjic-1157	166	13	substitutions	substitution	NOUN
hjic-1157	166	14	of	of	ADP
hjic-1157	166	15	ser-48	ser-48	NOUN
hjic-1157	166	16	and	and	CCONJ
hjic-1157	166	17	phe-93	phe-93	NOUN
hjic-1157	166	18	,	,	PUNCT
hjic-1157	166	19	chem	chem	NOUN
hjic-1157	166	20	.	.	PUNCT
hjic-1157	167	1	biol	biol	PROPN
hjic-1157	167	2	.	.	PUNCT
hjic-1157	168	1	interact	interact	VERB
hjic-1157	168	2	.	.	PUNCT
hjic-1157	168	3	,	,	PUNCT
hjic-1157	168	4	2017	2017	NUM
hjic-1157	168	5	,	,	PUNCT
hjic-1157	168	6	276	276	NUM
hjic-1157	168	7	,	,	PUNCT
hjic-1157	168	8	77–87	77–87	NUM
hjic-1157	168	9	doi	doi	NOUN
hjic-1157	168	10	:	:	PUNCT
hjic-1157	168	11	10.1016	10.1016	NUM
hjic-1157	168	12	/	/	SYM
hjic-1157	168	13	j.cbi.2016.12.016	j.cbi.2016.12.016	PROPN
hjic-1157	169	1	[	[	X
hjic-1157	169	2	12	12	NUM
hjic-1157	169	3	]	]	PUNCT
hjic-1157	169	4	giacomini	giacomini	PROPN
hjic-1157	169	5	,	,	PUNCT
hjic-1157	169	6	d.	d.	PROPN
hjic-1157	169	7	;	;	PUNCT
hjic-1157	169	8	galletti	galletti	PROPN
hjic-1157	169	9	,	,	PUNCT
hjic-1157	169	10	p.	p.	NOUN
hjic-1157	169	11	;	;	PUNCT
hjic-1157	169	12	quintavalla	quintavalla	NOUN
hjic-1157	169	13	,	,	PUNCT
hjic-1157	169	14	a.	a.	NOUN
hjic-1157	169	15	;	;	PUNCT
hjic-1157	169	16	gucciardo	gucciardo	PROPN
hjic-1157	169	17	,	,	PUNCT
hjic-1157	169	18	g.	g.	PROPN
hjic-1157	169	19	;	;	PUNCT
hjic-1157	169	20	paradisi	paradisi	PROPN
hjic-1157	169	21	,	,	PUNCT
hjic-1157	169	22	f.	f.	PROPN
hjic-1157	169	23	:	:	PUNCT
hjic-1157	169	24	highly	highly	ADV
hjic-1157	169	25	efficient	efficient	ADJ
hjic-1157	169	26	asymmetric	asymmetric	ADJ
hjic-1157	169	27	reduction	reduction	NOUN
hjic-1157	169	28	of	of	ADP
hjic-1157	169	29	arylpropionic	arylpropionic	ADJ
hjic-1157	169	30	aldehydes	aldehyde	NOUN
hjic-1157	169	31	by	by	ADP
hjic-1157	169	32	horse	horse	NOUN
hjic-1157	169	33	liver	liver	NOUN
hjic-1157	169	34	alcohol	alcohol	NOUN
hjic-1157	169	35	dehydrogenase	dehydrogenase	NOUN
hjic-1157	169	36	through	through	ADP
hjic-1157	169	37	dynamic	dynamic	ADJ
hjic-1157	169	38	kinetic	kinetic	NOUN
hjic-1157	169	39	resolution	resolution	NOUN
hjic-1157	169	40	,	,	PUNCT
hjic-1157	169	41	chem	chem	NOUN
hjic-1157	169	42	.	.	PUNCT
hjic-1157	170	1	commun	commun	PROPN
hjic-1157	170	2	.	.	PROPN
hjic-1157	170	3	,	,	PUNCT
hjic-1157	170	4	2007	2007	NUM
hjic-1157	170	5	,	,	PUNCT
hjic-1157	170	6	39	39	NUM
hjic-1157	170	7	,	,	PUNCT
hjic-1157	170	8	4038	4038	NUM
hjic-1157	170	9	–	–	PUNCT
hjic-1157	170	10	4040	4040	NUM
hjic-1157	170	11	doi	doi	NOUN
hjic-1157	170	12	:	:	PUNCT
hjic-1157	170	13	10.1039	10.1039	NUM
hjic-1157	171	1	/	/	SYM
hjic-1157	171	2	b712290j	b712290j	NOUN
hjic-1157	172	1	[	[	X
hjic-1157	172	2	13	13	NUM
hjic-1157	172	3	]	]	X
hjic-1157	172	4	hidekazu	hidekazu	NOUN
hjic-1157	172	5	,	,	PUNCT
hjic-1157	172	6	d.	d.	PROPN
hjic-1157	172	7	;	;	PUNCT
hjic-1157	172	8	yuri	yuri	PROPN
hjic-1157	172	9	,	,	PUNCT
hjic-1157	172	10	n.	n.	PROPN
hjic-1157	172	11	toyokichi	toyokichi	PROPN
hjic-1157	172	12	,	,	PUNCT
hjic-1157	172	13	k.	k.	PROPN
hjic-1157	172	14	:	:	PUNCT
hjic-1157	172	15	mass	mass	ADJ
hjic-1157	172	16	transfer	transfer	NOUN
hjic-1157	172	17	of	of	ADP
hjic-1157	172	18	acetylacetone	acetylacetone	NOUN
hjic-1157	172	19	,	,	PUNCT
hjic-1157	172	20	ethylene	ethylene	NOUN
hjic-1157	172	21	glycol	glycol	NOUN
hjic-1157	172	22	mono	mono	NOUN
hjic-1157	172	23	-	-	PUNCT
hjic-1157	172	24	n	n	CCONJ
hjic-1157	172	25	-	-	PUNCT
hjic-1157	172	26	butyl	butyl	NOUN
hjic-1157	172	27	ether	ether	NOUN
hjic-1157	172	28	and	and	CCONJ
hjic-1157	172	29	ethylene	ethylene	NOUN
hjic-1157	172	30	glycol	glycol	NOUN
hjic-1157	172	31	monophenyl	monophenyl	NOUN
hjic-1157	172	32	ether	ether	NOUN
hjic-1157	172	33	across	across	ADP
hjic-1157	172	34	water	water	NOUN
hjic-1157	172	35	-	-	PUNCT
hjic-1157	172	36	carbon	carbon	NOUN
hjic-1157	172	37	tetrachloride	tetrachloride	NOUN
hjic-1157	172	38	and	and	CCONJ
hjic-1157	172	39	water	water	NOUN
hjic-1157	172	40	-	-	PUNCT
hjic-1157	172	41	chloroform	chloroform	NOUN
hjic-1157	172	42	interfaces	interface	NOUN
hjic-1157	172	43	,	,	PUNCT
hjic-1157	172	44	anal	anal	NOUN
hjic-1157	172	45	.	.	PUNCT
hjic-1157	173	1	chim	chim	PROPN
hjic-1157	173	2	.	.	PUNCT
hjic-1157	174	1	acta	acta	PROPN
hjic-1157	174	2	,	,	PUNCT
hjic-1157	174	3	1990	1990	NUM
hjic-1157	174	4	,	,	PUNCT
hjic-1157	174	5	237	237	NUM
hjic-1157	174	6	,	,	PUNCT
hjic-1157	174	7	237–240	237–240	NUM
hjic-1157	174	8	doi	doi	NOUN
hjic-1157	174	9	:	:	PUNCT
hjic-1157	174	10	10.1016	10.1016	NUM
hjic-1157	174	11	/	/	SYM
hjic-1157	174	12	s0003	s0003	NUM
hjic-1157	174	13	-	-	NOUN
hjic-1157	174	14	2670(00)83923	2670(00)83923	NUM
hjic-1157	174	15	-	-	SYM
hjic-1157	174	16	9	9	NUM
hjic-1157	175	1	[	[	SYM
hjic-1157	175	2	14	14	NUM
hjic-1157	175	3	]	]	X
hjic-1157	175	4	kelemen	kelemen	PROPN
hjic-1157	175	5	-	-	PUNCT
hjic-1157	175	6	horváth	horváth	PROPN
hjic-1157	175	7	,	,	PUNCT
hjic-1157	175	8	i.	i.	NOUN
hjic-1157	175	9	;	;	PUNCT
hjic-1157	175	10	nemestóthy	nemestóthy	ADJ
hjic-1157	175	11	,	,	PUNCT
hjic-1157	175	12	n.	n.	NOUN
hjic-1157	175	13	;	;	PUNCT
hjic-1157	175	14	bélafi	bélafi	PROPN
hjic-1157	175	15	-	-	PUNCT
hjic-1157	175	16	bakó	bakó	PROPN
hjic-1157	175	17	,	,	PUNCT
hjic-1157	175	18	k.	k.	PROPN
hjic-1157	175	19	;	;	PUNCT
hjic-1157	175	20	gubicza	gubicza	PROPN
hjic-1157	175	21	,	,	PUNCT
hjic-1157	175	22	l.	l.	PROPN
hjic-1157	175	23	:	:	PUNCT
hjic-1157	175	24	stereoselective	stereoselective	ADJ
hjic-1157	175	25	reduction	reduction	NOUN
hjic-1157	175	26	of	of	ADP
hjic-1157	175	27	2phenylpropionaldehyde	2phenylpropionaldehyde	NUM
hjic-1157	175	28	by	by	ADP
hjic-1157	175	29	alcohol	alcohol	NOUN
hjic-1157	175	30	dehydrogenase	dehydrogenase	NOUN
hjic-1157	175	31	with	with	ADP
hjic-1157	175	32	cofactor	cofactor	NOUN
hjic-1157	175	33	regeneration	regeneration	NOUN
hjic-1157	175	34	,	,	PUNCT
hjic-1157	175	35	chem	chem	NOUN
hjic-1157	175	36	.	.	PUNCT
hjic-1157	176	1	pap	pap	NOUN
hjic-1157	176	2	.	.	PROPN
hjic-1157	176	3	,	,	PUNCT
hjic-1157	176	4	2002	2002	NUM
hjic-1157	176	5	,	,	PUNCT
hjic-1157	176	6	56	56	NUM
hjic-1157	176	7	,	,	PUNCT
hjic-1157	176	8	52–56	52–56	NUM
hjic-1157	176	9	url	url	X
hjic-1157	177	1	[	[	X
hjic-1157	177	2	15	15	NUM
hjic-1157	177	3	]	]	X
hjic-1157	177	4	manevski	manevski	NOUN
hjic-1157	177	5	,	,	PUNCT
hjic-1157	177	6	n.	n.	NOUN
hjic-1157	177	7	:	:	PUNCT
hjic-1157	177	8	activity	activity	NOUN
hjic-1157	177	9	and	and	CCONJ
hjic-1157	177	10	enzyme	enzyme	NOUN
hjic-1157	177	11	kinetics	kinetic	NOUN
hjic-1157	177	12	of	of	ADP
hjic-1157	177	13	human	human	PROPN
hjic-1157	177	14	udp	udp	PROPN
hjic-1157	177	15	-	-	NOUN
hjic-1157	177	16	glucuronosyltransferases	glucuronosyltransferase	NOUN
hjic-1157	177	17	:	:	PUNCT
hjic-1157	177	18	studies	study	NOUN
hjic-1157	177	19	of	of	ADP
hjic-1157	177	20	psilocin	psilocin	ADJ
hjic-1157	177	21	glucuronidation	glucuronidation	NOUN
hjic-1157	177	22	and	and	CCONJ
hjic-1157	177	23	the	the	DET
hjic-1157	177	24	effects	effect	NOUN
hjic-1157	177	25	of	of	ADP
hjic-1157	177	26	albumin	albumin	NOUN
hjic-1157	177	27	on	on	ADP
hjic-1157	177	28	the	the	DET
hjic-1157	177	29	enzyme	enzyme	NOUN
hjic-1157	177	30	kinetic	kinetic	ADJ
hjic-1157	177	31	mechanism	mechanism	NOUN
hjic-1157	177	32	,	,	PUNCT
hjic-1157	177	33	academic	academic	ADJ
hjic-1157	177	34	dissertation	dissertation	NOUN
hjic-1157	177	35	,	,	PUNCT
hjic-1157	177	36	university	university	NOUN
hjic-1157	177	37	of	of	ADP
hjic-1157	177	38	helsinki	helsinki	PROPN
hjic-1157	177	39	,	,	PUNCT
hjic-1157	177	40	2013	2013	NUM
hjic-1157	177	41	url	url	X
hjic-1157	178	1	[	[	X
hjic-1157	178	2	16	16	NUM
hjic-1157	178	3	]	]	X
hjic-1157	178	4	rapp	rapp	PROPN
hjic-1157	178	5	,	,	PUNCT
hjic-1157	178	6	c.	c.	NOUN
hjic-1157	178	7	;	;	PUNCT
hjic-1157	178	8	pival	pival	NOUN
hjic-1157	178	9	-	-	PUNCT
hjic-1157	178	10	marko	marko	PROPN
hjic-1157	178	11	,	,	PUNCT
hjic-1157	178	12	s.	s.	PROPN
hjic-1157	178	13	;	;	PUNCT
hjic-1157	178	14	tassano	tassano	PROPN
hjic-1157	178	15	,	,	PUNCT
hjic-1157	178	16	e.	e.	PROPN
hjic-1157	178	17	;	;	PUNCT
hjic-1157	178	18	nidetzky	nidetzky	PROPN
hjic-1157	178	19	,	,	PUNCT
hjic-1157	178	20	b.	b.	PROPN
hjic-1157	178	21	;	;	PUNCT
hjic-1157	178	22	kratzer	kratzer	PROPN
hjic-1157	178	23	,	,	PUNCT
hjic-1157	178	24	r.	r.	PROPN
hjic-1157	178	25	:	:	PUNCT
hjic-1157	178	26	reductive	reductive	ADJ
hjic-1157	178	27	enzymatic	enzymatic	ADJ
hjic-1157	178	28	dynamic	dynamic	ADJ
hjic-1157	178	29	kinetic	kinetic	NOUN
hjic-1157	178	30	resolution	resolution	NOUN
hjic-1157	178	31	affording	afford	VERB
hjic-1157	178	32	115	115	NUM
hjic-1157	178	33	g	g	NOUN
hjic-1157	178	34	/	/	SYM
hjic-1157	178	35	l	l	NOUN
hjic-1157	178	36	(	(	PUNCT
hjic-1157	178	37	s)-2phenylpropanol	s)-2phenylpropanol	PROPN
hjic-1157	178	38	,	,	PUNCT
hjic-1157	178	39	bmc	bmc	ADJ
hjic-1157	178	40	biotechnol	biotechnol	NOUN
hjic-1157	178	41	.	.	PUNCT
hjic-1157	178	42	,	,	PUNCT
hjic-1157	178	43	2021	2021	NUM
hjic-1157	178	44	,	,	PUNCT
hjic-1157	178	45	21	21	NUM
hjic-1157	178	46	,	,	PUNCT
hjic-1157	178	47	58	58	NUM
hjic-1157	178	48	doi	doi	NOUN
hjic-1157	178	49	:	:	PUNCT
hjic-1157	178	50	10.1186	10.1186	NUM
hjic-1157	178	51	/	/	SYM
hjic-1157	178	52	s12896	s12896	NOUN
hjic-1157	178	53	-	-	PUNCT
hjic-1157	178	54	021	021	NUM
hjic-1157	178	55	-	-	PUNCT
hjic-1157	178	56	00715	00715	NUM
hjic-1157	178	57	-	-	PUNCT
hjic-1157	178	58	5	5	NUM
hjic-1157	178	59	hungarian	hungarian	ADJ
hjic-1157	178	60	journal	journal	NOUN
hjic-1157	178	61	of	of	ADP
hjic-1157	178	62	industry	industry	NOUN
hjic-1157	178	63	and	and	CCONJ
hjic-1157	178	64	chemistry	chemistry	NOUN
hjic-1157	178	65	https://doi.org/10.1016/j.fct.2011.10.023	https://doi.org/10.1016/j.fct.2011.10.023	NOUN
hjic-1157	178	66	https://doi.org/10.1186/s12896-021-00715-5	https://doi.org/10.1186/s12896-021-00715-5	NUM
hjic-1157	178	67	https://doi.org/10.1007/978-3-642-17907-5_5	https://doi.org/10.1007/978-3-642-17907-5_5	PROPN
hjic-1157	178	68	https://doi.org/10.33927/hjic-2020-22	https://doi.org/10.33927/hjic-2020-22	X
hjic-1157	178	69	https://doi.org/10.1073/pnas	https://doi.org/10.1073/pna	NOUN
hjic-1157	178	70	.	.	PUNCT
hjic-1157	178	71	0306866101	0306866101	NUM
hjic-1157	179	1	https://doi.org/10.1515/znc-2010-1-201	https://doi.org/10.1515/znc-2010-1-201	NOUN
hjic-1157	179	2	https://doi.org/10.1186/1475-2859-7-25	https://doi.org/10.1186/1475-2859-7-25	VERB
hjic-1157	180	1	https://doi.org/10.1002/9781118596784.ssd036	https://doi.org/10.1002/9781118596784.ssd036	PROPN
hjic-1157	180	2	https://doi.org/10.1002/9781118596784.ssd036	https://doi.org/10.1002/9781118596784.ssd036	PROPN
hjic-1157	180	3	https://doi.org/10.1016/j.biortech.2010.06.044	https://doi.org/10.1016/j.biortech.2010.06.044	NUM
hjic-1157	180	4	https://doi.org/10.1002/cctc.201300640	https://doi.org/10.1002/cctc.201300640	ADJ
hjic-1157	180	5	https://doi.org/10.1016/j.cbi.2016.12.016	https://doi.org/10.1016/j.cbi.2016.12.016	PROPN
hjic-1157	180	6	https://doi.org/10.1039/b712290j	https://doi.org/10.1039/b712290j	PROPN
hjic-1157	180	7	https://doi.org/10.1016/s0003-2670(00)83923-9	https://doi.org/10.1016/s0003-2670(00)83923-9	ADJ
hjic-1157	180	8	https://www.chemicalpapers.com/file_access.php?file=561a52.pdf	https://www.chemicalpapers.com/file_access.php?file=561a52.pdf	NOUN
hjic-1157	180	9	https://helda.helsinki.fi/bitstream/handle/10138/38186/activity.pdf?sequence=1&isallowed=y	https://helda.helsinki.fi/bitstream/handle/10138/38186/activity.pdf?sequence=1&isallowed=y	NOUN
hjic-1157	180	10	https://doi.org/10.1186/s12896-021-00715-5	https://doi.org/10.1186/s12896-021-00715-5	NUM
hjic-1157	180	11	introduction	introduction	NOUN
hjic-1157	180	12	experimental	experimental	ADJ
hjic-1157	180	13	methods	method	NOUN
hjic-1157	180	14	applied	apply	VERB
hjic-1157	180	15	chemicals	chemical	NOUN
hjic-1157	180	16	activity	activity	NOUN
hjic-1157	180	17	measurements	measurement	VERB
hjic-1157	180	18	mass	mass	ADJ
hjic-1157	180	19	-	-	PUNCT
hjic-1157	180	20	transfer	transfer	NOUN
hjic-1157	180	21	rate	rate	NOUN
hjic-1157	180	22	kinetics	kinetic	NOUN
hjic-1157	180	23	enantioselectivity	enantioselectivity	NOUN
hjic-1157	180	24	results	result	NOUN
hjic-1157	180	25	and	and	CCONJ
hjic-1157	180	26	evaluation	evaluation	NOUN
hjic-1157	180	27	kinetics	kinetic	NOUN
hjic-1157	180	28	activity	activity	NOUN
hjic-1157	180	29	mass	mass	NOUN
hjic-1157	180	30	transfer	transfer	NOUN
hjic-1157	180	31	through	through	ADP
hjic-1157	180	32	the	the	DET
hjic-1157	180	33	organic	organic	ADJ
hjic-1157	180	34	–	–	PUNCT
hjic-1157	180	35	water	water	NOUN
hjic-1157	180	36	interface	interface	NOUN
hjic-1157	180	37	enantioselectivity	enantioselectivity	NOUN
hjic-1157	180	38	conclusion	conclusion	NOUN