id	sid	tid	token	lemma	pos
iajs-1229	1	1	invivo	invivo	ADJ
iajs-1229	1	2	study	study	NOUN
iajs-1229	1	3	of	of	ADP
iajs-1229	1	4	2002	2002	NUM
iajs-1229	1	5	(	(	PUNCT
iajs-1229	1	6	22مجلة	22مجلة	NUM
iajs-1229	1	7	ابن	ابن	VERB
iajs-1229	1	8	الهيثم	الهيثم	ADJ
iajs-1229	1	9	للعلوم	للعلوم	PROPN
iajs-1229	1	10	الصرفة	الصرفة	PROPN
iajs-1229	1	11	والتطبيقية	والتطبيقية	NOUN
iajs-1229	1	12	المجلد	المجلد	ADV
iajs-1229	1	13	)	)	PUNCT
iajs-1229	2	1	5،6	5،6	NUM
iajs-1229	2	2	-(يلو	-(يلو	PUNCT
iajs-1229	2	3	)	)	PUNCT
iajs-1229	3	1	استيل	استيل	NOUN
iajs-1229	3	2	سالس-3دراسة	سالس-3دراسة	PUNCT
iajs-1229	3	3	مختبرية	مختبرية	NOUN
iajs-1229	3	4	للمركبات	للمركبات	NOUN
iajs-1229	3	5	-ايزوبروبليدين	-ايزوبروبليدين	NOUN
iajs-1229	4	1	o	o	NOUN
iajs-1229	4	2	*	*	PUNCT
iajs-1229	4	3	*	*	PROPN
iajs-1229	4	4	نزار	نزار	PROPN
iajs-1229	4	5	احمد	احمد	VERB
iajs-1229	4	6	ناجي	ناجي	NOUN
iajs-1229	4	7	،	،	NOUN
iajs-1229	4	8	*	*	PUNCT
iajs-1229	4	9	عدنان	عدنان	PROPN
iajs-1229	4	10	ابراهيم	ابراهيم	NOUN
iajs-1229	4	11	عبودمخلص	عبودمخلص	NOUN
iajs-1229	4	12	،	،	X
iajs-1229	4	13	فراس	فراس	PROPN
iajs-1229	4	14	طاهر	طاهر	NOUN
iajs-1229	4	15	ماهر	ماهر	X
iajs-1229	4	16	،	،	X
iajs-1229	4	17	عبد	عبد	ADJ
iajs-1229	4	18	الجبار	الجبار	NOUN
iajs-1229	4	19	عبد	عبد	PROPN
iajs-1229	4	20	القادر	القادر	PROPN
iajs-1229	4	21	جامعة	جامعة	PROPN
iajs-1229	4	22	بغداد	بغداد	PROPN
iajs-1229	4	23	ثم	ثم	ADP
iajs-1229	4	24	،	،	PROPN
iajs-1229	4	25	ابن	ابن	X
iajs-1229	4	26	الهي	الهي	PROPN
iajs-1229	4	27	–	–	PUNCT
iajs-1229	4	28	كلية	كلية	NOUN
iajs-1229	4	29	التربية	التربية	NOUN
iajs-1229	4	30	قسم	قسم	PROPN
iajs-1229	4	31	الكيمياء	الكيمياء	PROPN
iajs-1229	4	32	،	،	PROPN
iajs-1229	5	1	وزارة	وزارة	PROPN
iajs-1229	5	2	العلوم	العلوم	PROPN
iajs-1229	5	3	والتكنلوجيا	والتكنلوجيا	NOUN
iajs-1229	5	4	*	*	PUNCT
iajs-1229	5	5	*	*	PUNCT
iajs-1229	5	6	كلية	كلية	NOUN
iajs-1229	5	7	العلوم	العلوم	NOUN
iajs-1229	5	8	،	،	X
iajs-1229	5	9	جامعة	جامعة	X
iajs-1229	5	10	تكريت	تكريت	NOUN
iajs-1229	5	11	الخالصة	الخالصة	PROPN
iajs-1229	5	12	(	(	PUNCT
iajs-1229	5	13	للمركبات	للمركبات	NOUN
iajs-1229	5	14	:	:	PUNCT
iajs-1229	5	15	invivoاجريت	invivoاجريت	VERB
iajs-1229	5	16	دراسة	دراسة	PROPN
iajs-1229	5	17	في	في	ADP
iajs-1229	5	18	داخل	داخل	PROPN
iajs-1229	5	19	جسم	جسم	AUX
iajs-1229	5	20	الكائن	الكائن	VERB
iajs-1229	5	21	الحي	الحي	ADV
iajs-1229	5	22	)	)	PUNCT
iajs-1229	6	1	3-(acetyl	3-(acetyl	NUM
iajs-1229	6	2	salicyloyl)-5,6	salicyloyl)-5,6	NOUN
iajs-1229	6	3	–	–	PUNCT
iajs-1229	6	4	o	o	NOUN
iajs-1229	6	5	-	-	PUNCT
iajs-1229	6	6	isopropylidene	isopropylidene	ADJ
iajs-1229	6	7	-	-	PUNCT
iajs-1229	6	8	l	l	NOUN
iajs-1229	6	9	-	-	ADJ
iajs-1229	6	10	ascorbic	ascorbic	ADJ
iajs-1229	6	11	acid	acid	NOUN
iajs-1229	6	12	,	,	PUNCT
iajs-1229	6	13	2,3(acetyl	2,3(acetyl	NUM
iajs-1229	6	14	salicyloyl)-5,6	salicyloyl)-5,6	ADJ
iajs-1229	6	15	–	–	PUNCT
iajs-1229	6	16	oisopropylidene	oisopropylidene	ADJ
iajs-1229	6	17	-	-	PUNCT
iajs-1229	6	18	l	l	NOUN
iajs-1229	6	19	-	-	ADJ
iajs-1229	6	20	ascorbic	ascorbic	ADJ
iajs-1229	6	21	acid	acid	NOUN
iajs-1229	6	22	and	and	CCONJ
iajs-1229	6	23	2,3,5,6	2,3,5,6	NUM
iajs-1229	6	24	-	-	PUNCT
iajs-1229	6	25	tetra(acetyl	tetra(acetyl	VERB
iajs-1229	6	26	salicyloyl)-l	salicyloyl)-l	NOUN
iajs-1229	6	27	-	-	PUNCT
iajs-1229	6	28	ascorbic	ascorbic	NOUN
iajs-1229	6	29	acid	acid	NOUN
iajs-1229	6	30	(	(	PUNCT
iajs-1229	6	31	سدااات	سدااات	NOUN
iajs-1229	6	32	مدن	مدن	NOUN
iajs-1229	6	33	ااءدال	ااءدال	NOUN
iajs-1229	6	34	الحيدوان	الحيدوان	PROPN
iajs-1229	6	35	الجرادة	الجرادة	PROPN
iajs-1229	6	36	03,3,3,3,3,2وقياس	03,3,3,3,3,2وقياس	PROPN
iajs-1229	6	37	تركيز	تركيز	NOUN
iajs-1229	6	38	االسبرين	االسبرين	PROPN
iajs-1229	6	39	المتحرر	المتحرر	PROPN
iajs-1229	6	40	في	في	ADP
iajs-1229	6	41	مصل	مصل	NOUN
iajs-1229	6	42	الدم	الدم	PROPN
iajs-1229	6	43	بعدد	بعدد	VERB
iajs-1229	6	44	مدرور	مدرور	NOUN
iajs-1229	6	45	)	)	PUNCT
iajs-1229	7	1	اجع	اجع	PROPN
iajs-1229	7	2	العلمية	العلمية	PROPN
iajs-1229	7	3	.حيث	.حيث	PRON
iajs-1229	8	1	اظهرت	اظهرت	PROPN
iajs-1229	8	2	النتائج	النتائج	PROPN
iajs-1229	8	3	ان	ان	PROPN
iajs-1229	8	4	االى	االى	PROPN
iajs-1229	8	5	تركيز	تركيز	NOUN
iajs-1229	8	6	لالسبرين	لالسبرين	PROPN
iajs-1229	8	7	كان	كان	PROPN
iajs-1229	8	8	بعد	بعد	PROPN
iajs-1229	8	9	اربع	اربع	PROPN
iajs-1229	8	10	من	من	PRON
iajs-1229	8	11	ااءال	ااءال	PROPN
iajs-1229	8	12	الحيوان	الحيوان	PROPN
iajs-1229	8	13	الجراة	الجراة	PROPN
iajs-1229	8	14	وهذا	وهذا	PROPN
iajs-1229	8	15	يتءابق	يتءابق	PROPN
iajs-1229	8	16	مع	مع	ADP
iajs-1229	8	17	المر	المر	PROPN
iajs-1229	8	18	ibn	ibn	PROPN
iajs-1229	8	19	alhaitham	alhaitham	PROPN
iajs-1229	8	20	j.	j.	PROPN
iajs-1229	8	21	for	for	ADP
iajs-1229	8	22	pure	pure	ADJ
iajs-1229	8	23	&	&	CCONJ
iajs-1229	8	24	appl	appl	PROPN
iajs-1229	8	25	.	.	PUNCT
iajs-1229	9	1	sci	sci	PROPN
iajs-1229	9	2	vol.22	vol.22	PROPN
iajs-1229	9	3	(	(	PUNCT
iajs-1229	9	4	2	2	NUM
iajs-1229	9	5	)	)	PUNCT
iajs-1229	9	6	2009	2009	NUM
iajs-1229	9	7	in	in	ADP
iajs-1229	9	8	vivo	vivo	NOUN
iajs-1229	9	9	study	study	NOUN
iajs-1229	9	10	of	of	ADP
iajs-1229	9	11	compounds	compound	NOUN
iajs-1229	9	12	3-(acetyl	3-(acetyl	NUM
iajs-1229	9	13	salicyloyl)-5,6	salicyloyl)-5,6	ADJ
iajs-1229	9	14	–	–	PUNCT
iajs-1229	9	15	oisopropylidene	oisopropylidene	ADJ
iajs-1229	9	16	-	-	PUNCT
iajs-1229	9	17	l	l	NOUN
iajs-1229	9	18	-	-	ADJ
iajs-1229	9	19	ascorbic	ascorbic	ADJ
iajs-1229	9	20	acid	acid	NOUN
iajs-1229	9	21	,	,	PUNCT
iajs-1229	9	22	2,3(acetyl	2,3(acetyl	NUM
iajs-1229	9	23	salicyloyl)-5,6	salicyloyl)-5,6	NOUN
iajs-1229	9	24	–	–	PUNCT
iajs-1229	9	25	o	o	NOUN
iajs-1229	9	26	-	-	PUNCT
iajs-1229	9	27	isopropylidene	isopropylidene	ADJ
iajs-1229	9	28	-	-	PUNCT
iajs-1229	9	29	l	l	NOUN
iajs-1229	9	30	-	-	ADJ
iajs-1229	9	31	ascorbic	ascorbic	ADJ
iajs-1229	9	32	acid	acid	NOUN
iajs-1229	9	33	and	and	CCONJ
iajs-1229	9	34	2,3,5,6tetra(acetyl	2,3,5,6tetra(acetyl	NUM
iajs-1229	9	35	salicyloyl)-l	salicyloyl)-l	NOUN
iajs-1229	9	36	-	-	PUNCT
iajs-1229	9	37	ascorbic	ascorbic	NOUN
iajs-1229	9	38	acid	acid	NOUN
iajs-1229	9	39	f.	f.	PROPN
iajs-1229	9	40	t.	t.	PROPN
iajs-1229	9	41	maher	maher	PROPN
iajs-1229	9	42	,	,	PUNCT
iajs-1229	9	43	a	a	PROPN
iajs-1229	9	44	-	-	PUNCT
iajs-1229	9	45	j.	j.	PROPN
iajs-1229	9	46	mukhlis	mukhlis	PROPN
iajs-1229	9	47	,	,	PUNCT
iajs-1229	9	48	*	*	PUNCT
iajs-1229	9	49	a.	a.	PROPN
iajs-1229	9	50	i.	i.	PROPN
iajs-1229	9	51	abuod	abuod	PROPN
iajs-1229	9	52	,	,	PUNCT
iajs-1229	9	53	*	*	PUNCT
iajs-1229	9	54	*	*	PUNCT
iajs-1229	9	55	n.	n.	PROPN
iajs-1229	9	56	a.	a.	PROPN
iajs-1229	9	57	naji	naji	PROPN
iajs-1229	9	58	department	department	PROPN
iajs-1229	9	59	of	of	ADP
iajs-1229	9	60	chemistry	chemistry	NOUN
iajs-1229	9	61	,	,	PUNCT
iajs-1229	9	62	college	college	NOUN
iajs-1229	9	63	of	of	ADP
iajs-1229	9	64	education	education	NOUN
iajs-1229	9	65	,	,	PUNCT
iajs-1229	9	66	ibn	ibn	PROPN
iajs-1229	9	67	al	al	PROPN
iajs-1229	9	68	-	-	PUNCT
iajs-1229	9	69	haithem	haithem	PROPN
iajs-1229	9	70	,	,	PUNCT
iajs-1229	9	71	university	university	NOUN
iajs-1229	9	72	of	of	ADP
iajs-1229	9	73	baghdad	baghdad	PROPN
iajs-1229	9	74	*	*	PUNCT
iajs-1229	9	75	ministry	ministry	PROPN
iajs-1229	9	76	of	of	ADP
iajs-1229	9	77	science	science	NOUN
iajs-1229	9	78	and	and	CCONJ
iajs-1229	9	79	technology	technology	NOUN
iajs-1229	9	80	*	*	PUNCT
iajs-1229	9	81	*	*	PUNCT
iajs-1229	9	82	department	department	NOUN
iajs-1229	9	83	of	of	ADP
iajs-1229	9	84	chemistry	chemistry	NOUN
iajs-1229	9	85	college	college	PROPN
iajs-1229	9	86	of	of	ADP
iajs-1229	9	87	science	science	NOUN
iajs-1229	9	88	–	–	PUNCT
iajs-1229	9	89	tikrit	tikrit	NOUN
iajs-1229	9	90	university	university	NOUN
iajs-1229	9	91	abstract	abstract	NOUN
iajs-1229	9	92	in	in	ADP
iajs-1229	9	93	vivo	vivo	NOUN
iajs-1229	9	94	study	study	NOUN
iajs-1229	9	95	was	be	AUX
iajs-1229	9	96	made	make	VERB
iajs-1229	9	97	for	for	ADP
iajs-1229	9	98	the	the	DET
iajs-1229	9	99	coumpounds	coumpound	NOUN
iajs-1229	9	100	3-(ocetyl	3-(ocetyl	NUM
iajs-1229	9	101	salicyloyl)-5,6	salicyloyl)-5,6	VERB
iajs-1229	9	102	-	-	PUNCT
iajs-1229	9	103	o	o	NOUN
iajs-1229	9	104	-	-	ADJ
iajs-1229	9	105	isoprpy	isoprpy	NOUN
iajs-1229	9	106	lidenel	lidenel	NOUN
iajs-1229	9	107	-	-	PUNCT
iajs-1229	9	108	ascorbicocid,2,3-(acetyl	ascorbicocid,2,3-(acetyl	NOUN
iajs-1229	9	109	salicyloyl	salicyloyl	NOUN
iajs-1229	9	110	)	)	PUNCT
iajs-1229	9	111	-5,6	-5,6	NUM
iajs-1229	9	112	-	-	PUNCT
iajs-1229	9	113	oisopropylidene	oisopropylidene	ADJ
iajs-1229	9	114	-	-	PUNCT
iajs-1229	9	115	l	l	NOUN
iajs-1229	9	116	-	-	ADJ
iajs-1229	9	117	ascorbic	ascorbic	ADJ
iajs-1229	9	118	acid	acid	NOUN
iajs-1229	9	119	and	and	CCONJ
iajs-1229	9	120	2,3,5,6(acetyl	2,3,5,6(acetyl	NUM
iajs-1229	9	121	salicyloyl	salicyloyl	ADJ
iajs-1229	9	122	)	)	PUNCT
iajs-1229	9	123	-lascorbic	-lascorbic	ADJ
iajs-1229	9	124	acid	acid	NOUN
iajs-1229	9	125	.and	.and	PUNCT
iajs-1229	10	1	a	a	DET
iajs-1229	10	2	measurement	measurement	NOUN
iajs-1229	10	3	was	be	AUX
iajs-1229	10	4	mod	mod	ADJ
iajs-1229	10	5	for	for	ADP
iajs-1229	10	6	the	the	DET
iajs-1229	10	7	concentration	concentration	NOUN
iajs-1229	10	8	of	of	ADP
iajs-1229	10	9	the	the	DET
iajs-1229	10	10	liberated	liberated	ADJ
iajs-1229	10	11	aspirin	aspirin	NOUN
iajs-1229	10	12	in	in	ADP
iajs-1229	10	13	blood	blood	NOUN
iajs-1229	10	14	samples	sample	NOUN
iajs-1229	10	15	a	a	DET
iajs-1229	10	16	fter	fter	NOUN
iajs-1229	10	17	(	(	PUNCT
iajs-1229	10	18	2,3,4,6,8,10	2,3,4,6,8,10	NUM
iajs-1229	10	19	)	)	PUNCT
iajs-1229	10	20	hours	hour	NOUN
iajs-1229	10	21	of	of	ADP
iajs-1229	10	22	the	the	DET
iajs-1229	10	23	initial	initial	ADJ
iajs-1229	10	24	dose	dose	NOUN
iajs-1229	10	25	for	for	ADP
iajs-1229	10	26	the	the	DET
iajs-1229	10	27	animal	animal	NOUN
iajs-1229	10	28	.the	.the	DET
iajs-1229	10	29	results	result	NOUN
iajs-1229	10	30	showed	show	VERB
iajs-1229	10	31	that	that	SCONJ
iajs-1229	10	32	the	the	DET
iajs-1229	10	33	highest	high	ADJ
iajs-1229	10	34	concentration	concentration	NOUN
iajs-1229	10	35	of	of	ADP
iajs-1229	10	36	aspirin	aspirin	NOUN
iajs-1229	10	37	was	be	AUX
iajs-1229	10	38	after	after	ADP
iajs-1229	10	39	four	four	NUM
iajs-1229	10	40	hours	hour	NOUN
iajs-1229	10	41	of	of	ADP
iajs-1229	10	42	giving	give	VERB
iajs-1229	10	43	the	the	DET
iajs-1229	10	44	dose	dose	NOUN
iajs-1229	10	45	to	to	ADP
iajs-1229	10	46	the	the	DET
iajs-1229	10	47	animal	animal	NOUN
iajs-1229	10	48	which	which	PRON
iajs-1229	10	49	is	be	AUX
iajs-1229	10	50	in	in	ADP
iajs-1229	10	51	accordance	accordance	NOUN
iajs-1229	10	52	with	with	ADP
iajs-1229	10	53	pharmacokinetics	pharmacokinetic	NOUN
iajs-1229	10	54	studies	study	NOUN
iajs-1229	10	55	introduction	introduction	NOUN
iajs-1229	10	56	aspirin	aspirin	NOUN
iajs-1229	10	57	,	,	PUNCT
iajs-1229	10	58	the	the	DET
iajs-1229	10	59	salicylic	salicylic	ADJ
iajs-1229	10	60	ester	ester	NOUN
iajs-1229	10	61	of	of	ADP
iajs-1229	10	62	acetic	acetic	ADJ
iajs-1229	10	63	acid	acid	NOUN
iajs-1229	10	64	,	,	PUNCT
iajs-1229	10	65	was	be	AUX
iajs-1229	10	66	introduced	introduce	VERB
iajs-1229	10	67	into	into	ADP
iajs-1229	10	68	medicine	medicine	NOUN
iajs-1229	10	69	in	in	ADP
iajs-1229	10	70	1899	1899	NUM
iajs-1229	10	71	and	and	CCONJ
iajs-1229	10	72	is	be	AUX
iajs-1229	10	73	used	use	VERB
iajs-1229	10	74	for	for	ADP
iajs-1229	10	75	its	its	PRON
iajs-1229	10	76	analgesic	analgesic	ADJ
iajs-1229	10	77	,	,	PUNCT
iajs-1229	10	78	antiinflammatory	antiinflammatory	NOUN
iajs-1229	10	79	,	,	PUNCT
iajs-1229	10	80	antipyretic	antipyretic	NOUN
iajs-1229	10	81	,	,	PUNCT
iajs-1229	10	82	and	and	CCONJ
iajs-1229	10	83	antithrombotic	antithrombotic	ADJ
iajs-1229	10	84	effects	effect	NOUN
iajs-1229	10	85	.	.	PUNCT
iajs-1229	11	1	once	once	ADV
iajs-1229	11	2	in	in	ADP
iajs-1229	11	3	the	the	DET
iajs-1229	11	4	body	body	NOUN
iajs-1229	11	5	,	,	PUNCT
iajs-1229	11	6	it	it	PRON
iajs-1229	11	7	is	be	AUX
iajs-1229	11	8	hydrolyzed	hydrolyze	VERB
iajs-1229	11	9	to	to	PART
iajs-1229	11	10	salicylate	salicylate	NOUN
iajs-1229	11	11	,	,	PUNCT
iajs-1229	11	12	which	which	PRON
iajs-1229	11	13	is	be	AUX
iajs-1229	11	14	also	also	ADV
iajs-1229	11	15	active	active	ADJ
iajs-1229	11	16	.	.	PUNCT
iajs-1229	12	1	the	the	DET
iajs-1229	12	2	antiinflammatory	antiinflammatory	NOUN
iajs-1229	12	3	and	and	CCONJ
iajs-1229	12	4	analgesic	analgesic	ADJ
iajs-1229	12	5	effects	effect	NOUN
iajs-1229	12	6	of	of	ADP
iajs-1229	12	7	aspirin	aspirin	NOUN
iajs-1229	12	8	are	be	AUX
iajs-1229	12	9	roughly	roughly	ADV
iajs-1229	12	10	equivalent	equivalent	ADJ
iajs-1229	12	11	to	to	ADP
iajs-1229	12	12	those	those	PRON
iajs-1229	12	13	of	of	ADP
iajs-1229	12	14	many	many	ADJ
iajs-1229	12	15	nsaids	nsaid	NOUN
iajs-1229	12	16	.	.	PUNCT
iajs-1229	13	1	aspirin	aspirin	PROPN
iajs-1229	13	2	is	be	AUX
iajs-1229	13	3	used	use	VERB
iajs-1229	13	4	in	in	ADP
iajs-1229	13	5	the	the	DET
iajs-1229	13	6	treatment	treatment	NOUN
iajs-1229	13	7	of	of	ADP
iajs-1229	13	8	many	many	ADJ
iajs-1229	13	9	inflammatory	inflammatory	ADJ
iajs-1229	13	10	and	and	CCONJ
iajs-1229	13	11	autoimmune	autoimmune	ADJ
iajs-1229	13	12	conditions	condition	NOUN
iajs-1229	13	13	such	such	ADJ
iajs-1229	13	14	as	as	ADP
iajs-1229	13	15	juvenile	juvenile	ADJ
iajs-1229	13	16	arthritis	arthritis	NOUN
iajs-1229	13	17	,	,	PUNCT
iajs-1229	13	18	rheumatoid	rheumatoid	NOUN
iajs-1229	13	19	arthritis	arthritis	NOUN
iajs-1229	13	20	,	,	PUNCT
iajs-1229	13	21	and	and	CCONJ
iajs-1229	13	22	osteoarthritis	osteoarthritis	NOUN
iajs-1229	13	23	.	.	PUNCT
iajs-1229	14	1	because	because	SCONJ
iajs-1229	14	2	of	of	ADP
iajs-1229	14	3	its	its	PRON
iajs-1229	14	4	antithrombotic	antithrombotic	ADJ
iajs-1229	14	5	effects	effect	NOUN
iajs-1229	14	6	,	,	PUNCT
iajs-1229	14	7	aspirin	aspirin	NOUN
iajs-1229	14	8	is	be	AUX
iajs-1229	14	9	useful	useful	ADJ
iajs-1229	14	10	in	in	ADP
iajs-1229	14	11	preventing	prevent	VERB
iajs-1229	14	12	or	or	CCONJ
iajs-1229	14	13	reducing	reduce	VERB
iajs-1229	14	14	the	the	DET
iajs-1229	14	15	risk	risk	NOUN
iajs-1229	14	16	of	of	ADP
iajs-1229	14	17	myocardial	myocardial	ADJ
iajs-1229	14	18	infarction	infarction	NOUN
iajs-1229	14	19	and	and	CCONJ
iajs-1229	14	20	recurring	recur	VERB
iajs-1229	14	21	transient	transient	ADJ
iajs-1229	14	22	ischemic	ischemic	ADJ
iajs-1229	14	23	attacks	attack	NOUN
iajs-1229	14	24	(	(	PUNCT
iajs-1229	14	25	tias	tias	PROPN
iajs-1229	14	26	)	)	PUNCT
iajs-1229	14	27	.	.	PUNCT
iajs-1229	15	1	aspirin	aspirin	PROPN
iajs-1229	15	2	was	be	AUX
iajs-1229	15	3	officially	officially	ADV
iajs-1229	15	4	approved	approve	VERB
iajs-1229	15	5	by	by	ADP
iajs-1229	15	6	the	the	DET
iajs-1229	15	7	fda	fda	PROPN
iajs-1229	15	8	in	in	ADP
iajs-1229	15	9	1939	1939	NUM
iajs-1229	15	10	.	.	PUNCT
iajs-1229	16	1	during	during	ADP
iajs-1229	16	2	most	most	ADJ
iajs-1229	16	3	of	of	ADP
iajs-1229	16	4	this	this	DET
iajs-1229	16	5	century	century	NOUN
iajs-1229	16	6	,	,	PUNCT
iajs-1229	16	7	it	it	PRON
iajs-1229	16	8	was	be	AUX
iajs-1229	16	9	mainly	mainly	ADV
iajs-1229	16	10	used	use	VERB
iajs-1229	16	11	for	for	ADP
iajs-1229	16	12	its	its	PRON
iajs-1229	16	13	antiinflammatory	antiinflammatory	NOUN
iajs-1229	16	14	and	and	CCONJ
iajs-1229	16	15	analgesic	analgesic	ADJ
iajs-1229	16	16	properties	property	NOUN
iajs-1229	16	17	.	.	PUNCT
iajs-1229	17	1	in	in	ADP
iajs-1229	17	2	the	the	DET
iajs-1229	17	3	1980s	1980	NOUN
iajs-1229	17	4	,	,	PUNCT
iajs-1229	17	5	its	its	PRON
iajs-1229	17	6	ability	ability	NOUN
iajs-1229	17	7	to	to	PART
iajs-1229	17	8	inhibit	inhibit	VERB
iajs-1229	17	9	platelet	platelet	NOUN
iajs-1229	17	10	aggregation	aggregation	NOUN
iajs-1229	17	11	was	be	AUX
iajs-1229	17	12	realized	realize	VERB
iajs-1229	17	13	and	and	CCONJ
iajs-1229	17	14	it	it	PRON
iajs-1229	17	15	became	become	VERB
iajs-1229	17	16	an	an	DET
iajs-1229	17	17	important	important	ADJ
iajs-1229	17	18	antithrombotic	antithrombotic	ADJ
iajs-1229	17	19	agent	agent	NOUN
iajs-1229	17	20	.	.	PUNCT
iajs-1229	18	1	more	more	ADV
iajs-1229	18	2	recently	recently	ADV
iajs-1229	18	3	,	,	PUNCT
iajs-1229	18	4	it	it	PRON
iajs-1229	18	5	has	have	AUX
iajs-1229	18	6	been	be	AUX
iajs-1229	18	7	shown	show	VERB
iajs-1229	18	8	that	that	SCONJ
iajs-1229	18	9	long	long	ADJ
iajs-1229	18	10	-	-	PUNCT
iajs-1229	18	11	term	term	NOUN
iajs-1229	18	12	(	(	PUNCT
iajs-1229	18	13	e.g.	e.g.	ADV
iajs-1229	18	14	,	,	PUNCT
iajs-1229	18	15	>	>	PUNCT
iajs-1229	18	16	=	=	SYM
iajs-1229	18	17	10	10	NUM
iajs-1229	18	18	years	year	NOUN
iajs-1229	18	19	)	)	PUNCT
iajs-1229	18	20	regular	regular	ADJ
iajs-1229	18	21	consumption	consumption	NOUN
iajs-1229	18	22	of	of	ADP
iajs-1229	18	23	aspirin	aspirin	NOUN
iajs-1229	18	24	may	may	AUX
iajs-1229	18	25	lower	lower	VERB
iajs-1229	18	26	the	the	DET
iajs-1229	18	27	risk	risk	NOUN
iajs-1229	18	28	of	of	ADP
iajs-1229	18	29	developing	develop	VERB
iajs-1229	18	30	colorectal	colorectal	ADJ
iajs-1229	18	31	cancer(1,2,3	cancer(1,2,3	NOUN
iajs-1229	18	32	)	)	PUNCT
iajs-1229	18	33	.	.	PUNCT
iajs-1229	19	1	it	it	PRON
iajs-1229	19	2	is	be	AUX
iajs-1229	19	3	now	now	ADV
iajs-1229	19	4	thought	think	VERB
iajs-1229	19	5	that	that	SCONJ
iajs-1229	19	6	aspirin	aspirin	NOUN
iajs-1229	19	7	may	may	AUX
iajs-1229	19	8	possess	possess	VERB
iajs-1229	19	9	antiproliferative	antiproliferative	ADJ
iajs-1229	19	10	actions	action	NOUN
iajs-1229	19	11	.	.	PUNCT
iajs-1229	20	1	a	a	DET
iajs-1229	20	2	sustained	sustain	VERB
iajs-1229	20	3	-	-	PUNCT
iajs-1229	20	4	release	release	NOUN
iajs-1229	20	5	aspirin	aspirin	NOUN
iajs-1229	20	6	(	(	PUNCT
iajs-1229	20	7	asacard	asacard	NOUN
iajs-1229	20	8	)	)	PUNCT
iajs-1229	20	9	was	be	AUX
iajs-1229	20	10	approved	approve	VERB
iajs-1229	20	11	for	for	ADP
iajs-1229	20	12	use	use	NOUN
iajs-1229	20	13	in	in	ADP
iajs-1229	20	14	the	the	DET
iajs-1229	20	15	uk	uk	PROPN
iajs-1229	20	16	in	in	ADP
iajs-1229	20	17	february	february	PROPN
iajs-1229	20	18	1998	1998	NUM
iajs-1229	20	19	;	;	PUNCT
iajs-1229	20	20	phase	phase	NOUN
iajs-1229	20	21	i	i	PRON
iajs-1229	20	22	studies	study	NOUN
iajs-1229	20	23	on	on	ADP
iajs-1229	20	24	this	this	DET
iajs-1229	20	25	product	product	NOUN
iajs-1229	20	26	were	be	AUX
iajs-1229	20	27	initiated	initiate	VERB
iajs-1229	20	28	in	in	ADP
iajs-1229	20	29	the	the	DET
iajs-1229	20	30	us	we	PRON
iajs-1229	20	31	also	also	ADV
iajs-1229	20	32	in	in	ADP
iajs-1229	20	33	february	february	PROPN
iajs-1229	20	34	1998(4	1998(4	NUM
iajs-1229	20	35	)	)	PUNCT
iajs-1229	20	36	several	several	ADJ
iajs-1229	20	37	interactions	interaction	NOUN
iajs-1229	20	38	occur	occur	VERB
iajs-1229	20	39	between	between	ADP
iajs-1229	20	40	acetazolamide	acetazolamide	NOUN
iajs-1229	20	41	and	and	CCONJ
iajs-1229	20	42	aspirin	aspirin	NOUN
iajs-1229	20	43	.	.	PUNCT
iajs-1229	21	1	salicylates	salicylate	NOUN
iajs-1229	21	2	displace	displace	VERB
iajs-1229	21	3	acetazolamide	acetazolamide	ADV
iajs-1229	21	4	from	from	ADP
iajs-1229	21	5	plasma	plasma	NOUN
iajs-1229	21	6	protein	protein	NOUN
iajs-1229	21	7	binding	bind	VERB
iajs-1229	21	8	sites	site	NOUN
iajs-1229	21	9	and	and	CCONJ
iajs-1229	21	10	also	also	ADV
iajs-1229	21	11	decrease	decrease	VERB
iajs-1229	21	12	acetazolamide	acetazolamide	ADV
iajs-1229	21	13	renal	renal	ADJ
iajs-1229	21	14	excretion	excretion	NOUN
iajs-1229	21	15	.	.	PUNCT
iajs-1229	22	1	conversely	conversely	ADV
iajs-1229	22	2	,	,	PUNCT
iajs-1229	22	3	acetazolamide	acetazolamide	ADV
iajs-1229	22	4	may	may	AUX
iajs-1229	22	5	increase	increase	VERB
iajs-1229	22	6	the	the	DET
iajs-1229	22	7	renal	renal	ADJ
iajs-1229	22	8	elimination	elimination	NOUN
iajs-1229	22	9	of	of	ADP
iajs-1229	22	10	salicylates	salicylate	NOUN
iajs-1229	22	11	by	by	ADP
iajs-1229	22	12	increasing	increase	VERB
iajs-1229	22	13	urinary	urinary	ADJ
iajs-1229	22	14	ph	ph	PROPN
iajs-1229	22	15	.	.	PROPN
iajs-1229	22	16	aspirin	aspirin	PROPN
iajs-1229	22	17	can	can	AUX
iajs-1229	22	18	precipitate	precipitate	VERB
iajs-1229	22	19	acetazolamide	acetazolamide	ADJ
iajs-1229	22	20	cns	cns	NOUN
iajs-1229	22	21	toxicity	toxicity	NOUN
iajs-1229	22	22	,	,	PUNCT
iajs-1229	22	23	however	however	ADV
iajs-1229	22	24	,	,	PUNCT
iajs-1229	22	25	the	the	DET
iajs-1229	22	26	effects	effect	NOUN
iajs-1229	22	27	of	of	ADP
iajs-1229	22	28	acetazolamide	acetazolamide	NOUN
iajs-1229	22	29	on	on	ADP
iajs-1229	22	30	aspirin	aspirin	NOUN
iajs-1229	22	31	may	may	AUX
iajs-1229	22	32	not	not	PART
iajs-1229	22	33	be	be	AUX
iajs-1229	22	34	clinically	clinically	ADV
iajs-1229	22	35	significant	significant	ADJ
iajs-1229	22	36	.	.	PUNCT
iajs-1229	23	1	the	the	DET
iajs-1229	23	2	risk	risk	NOUN
iajs-1229	23	3	of	of	ADP
iajs-1229	23	4	bleeding	bleeding	NOUN
iajs-1229	23	5	is	be	AUX
iajs-1229	23	6	increased	increase	VERB
iajs-1229	23	7	if	if	SCONJ
iajs-1229	23	8	aspirin	aspirin	NOUN
iajs-1229	23	9	is	be	AUX
iajs-1229	23	10	administered	administer	VERB
iajs-1229	23	11	to	to	ADP
iajs-1229	23	12	patients	patient	NOUN
iajs-1229	23	13	already	already	ADV
iajs-1229	23	14	receiving	receive	VERB
iajs-1229	23	15	anticoagulants	anticoagulant	NOUN
iajs-1229	23	16	.	.	PUNCT
iajs-1229	24	1	aspirin	aspirin	NOUN
iajs-1229	24	2	can	can	AUX
iajs-1229	24	3	displace	displace	VERB
iajs-1229	24	4	warfarin	warfarin	NOUN
iajs-1229	24	5	from	from	ADP
iajs-1229	24	6	protein	protein	NOUN
iajs-1229	24	7	-	-	PUNCT
iajs-1229	24	8	binding	bind	VERB
iajs-1229	24	9	sites	site	NOUN
iajs-1229	24	10	and	and	CCONJ
iajs-1229	24	11	can	can	AUX
iajs-1229	24	12	increase	increase	VERB
iajs-1229	24	13	the	the	DET
iajs-1229	24	14	risk	risk	NOUN
iajs-1229	24	15	of	of	ADP
iajs-1229	24	16	bleeding	bleed	VERB
iajs-1229	24	17	during	during	ADP
iajs-1229	24	18	heparin	heparin	ADJ
iajs-1229	24	19	or	or	CCONJ
iajs-1229	24	20	warfarin	warfarin	NOUN
iajs-1229	24	21	therapy	therapy	NOUN
iajs-1229	24	22	because	because	SCONJ
iajs-1229	24	23	of	of	ADP
iajs-1229	24	24	its	its	PRON
iajs-1229	24	25	effect	effect	NOUN
iajs-1229	24	26	on	on	ADP
iajs-1229	24	27	platelet	platelet	NOUN
iajs-1229	24	28	aggregation	aggregation	NOUN
iajs-1229	24	29	.	.	PUNCT
iajs-1229	25	1	aspirin	aspirin	NOUN
iajs-1229	25	2	-	-	PUNCT
iajs-1229	25	3	induced	induce	VERB
iajs-1229	25	4	gi	gi	NOUN
iajs-1229	25	5	bleeding	bleeding	NOUN
iajs-1229	25	6	may	may	AUX
iajs-1229	25	7	be	be	AUX
iajs-1229	25	8	worse	bad	ADJ
iajs-1229	25	9	in	in	ADP
iajs-1229	25	10	anticoagulated	anticoagulate	VERB
iajs-1229	25	11	patients	patient	NOUN
iajs-1229	25	12	.	.	PUNCT
iajs-1229	26	1	also	also	ADV
iajs-1229	26	2	,	,	PUNCT
iajs-1229	26	3	aspirin	aspirin	ADV
iajs-1229	26	4	,	,	PUNCT
iajs-1229	26	5	in	in	ADP
iajs-1229	26	6	high	high	ADJ
iajs-1229	26	7	-	-	PUNCT
iajs-1229	26	8	doses	dose	NOUN
iajs-1229	26	9	,	,	PUNCT
iajs-1229	26	10	has	have	VERB
iajs-1229	26	11	a	a	DET
iajs-1229	26	12	hypoprothrombinemic	hypoprothrombinemic	ADJ
iajs-1229	26	13	effect	effect	NOUN
iajs-1229	26	14	.	.	PUNCT
iajs-1229	27	1	aspirin	aspirin	NOUN
iajs-1229	27	2	and	and	CCONJ
iajs-1229	27	3	warfarin	warfarin	NOUN
iajs-1229	27	4	may	may	AUX
iajs-1229	27	5	be	be	AUX
iajs-1229	27	6	used	use	VERB
iajs-1229	27	7	together	together	ADV
iajs-1229	27	8	,	,	PUNCT
iajs-1229	27	9	however	however	ADV
iajs-1229	27	10	,	,	PUNCT
iajs-1229	27	11	if	if	SCONJ
iajs-1229	27	12	aspirin	aspirin	NOUN
iajs-1229	27	13	is	be	AUX
iajs-1229	27	14	administered	administer	VERB
iajs-1229	27	15	before	before	SCONJ
iajs-1229	27	16	warfarin	warfarin	NOUN
iajs-1229	27	17	therapy	therapy	NOUN
iajs-1229	27	18	is	be	AUX
iajs-1229	27	19	begun	begin	VERB
iajs-1229	27	20	.	.	PUNCT
iajs-1229	28	1	combination	combination	NOUN
iajs-1229	28	2	ibn	ibn	PROPN
iajs-1229	28	3	alhaitham	alhaitham	NOUN
iajs-1229	28	4	j.	j.	PROPN
iajs-1229	28	5	for	for	ADP
iajs-1229	28	6	pure	pure	ADJ
iajs-1229	28	7	&	&	CCONJ
iajs-1229	28	8	appl	appl	PROPN
iajs-1229	28	9	.	.	PUNCT
iajs-1229	29	1	sci	sci	PROPN
iajs-1229	29	2	vol.22	vol.22	PROPN
iajs-1229	29	3	(	(	PUNCT
iajs-1229	29	4	2	2	NUM
iajs-1229	29	5	)	)	PUNCT
iajs-1229	29	6	2009	2009	NUM
iajs-1229	29	7	therapy	therapy	NOUN
iajs-1229	29	8	with	with	ADP
iajs-1229	29	9	both	both	CCONJ
iajs-1229	29	10	aspirin	aspirin	NOUN
iajs-1229	29	11	and	and	CCONJ
iajs-1229	29	12	warfarin	warfarin	NOUN
iajs-1229	29	13	has	have	AUX
iajs-1229	29	14	been	be	AUX
iajs-1229	29	15	shown	show	VERB
iajs-1229	29	16	to	to	PART
iajs-1229	29	17	reduce	reduce	VERB
iajs-1229	29	18	mortality	mortality	NOUN
iajs-1229	29	19	compared	compare	VERB
iajs-1229	29	20	to	to	ADP
iajs-1229	29	21	warfarin	warfarin	NOUN
iajs-1229	29	22	therapy	therapy	NOUN
iajs-1229	29	23	alone	alone	ADV
iajs-1229	29	24	in	in	ADP
iajs-1229	29	25	patients	patient	NOUN
iajs-1229	29	26	with	with	ADP
iajs-1229	29	27	artificial	artificial	ADJ
iajs-1229	29	28	heart	heart	NOUN
iajs-1229	29	29	valves	valve	NOUN
iajs-1229	29	30	.	.	PUNCT
iajs-1229	30	1	aspirin	aspirin	PROPN
iajs-1229	30	2	can	can	AUX
iajs-1229	30	3	potentiate	potentiate	VERB
iajs-1229	30	4	the	the	DET
iajs-1229	30	5	anticoagulant	anticoagulant	ADJ
iajs-1229	30	6	effect	effect	NOUN
iajs-1229	30	7	of	of	ADP
iajs-1229	30	8	heparin	heparin	NOUN
iajs-1229	30	9	;	;	PUNCT
iajs-1229	30	10	however	however	ADV
iajs-1229	30	11	,	,	PUNCT
iajs-1229	30	12	these	these	DET
iajs-1229	30	13	two	two	NUM
iajs-1229	30	14	agents	agent	NOUN
iajs-1229	30	15	are	be	AUX
iajs-1229	30	16	often	often	ADV
iajs-1229	30	17	used	use	VERB
iajs-1229	30	18	together	together	ADV
iajs-1229	30	19	in	in	ADP
iajs-1229	30	20	the	the	DET
iajs-1229	30	21	treatment	treatment	NOUN
iajs-1229	30	22	of	of	ADP
iajs-1229	30	23	acute	acute	ADJ
iajs-1229	30	24	myocardial	myocardial	ADJ
iajs-1229	30	25	infarction	infarction	NOUN
iajs-1229	30	26	.	.	PUNCT
iajs-1229	31	1	regarding	regard	VERB
iajs-1229	31	2	thrombolytic	thrombolytic	ADJ
iajs-1229	31	3	agents	agent	NOUN
iajs-1229	31	4	,	,	PUNCT
iajs-1229	31	5	while	while	SCONJ
iajs-1229	31	6	the	the	DET
iajs-1229	31	7	risk	risk	NOUN
iajs-1229	31	8	of	of	ADP
iajs-1229	31	9	bleeding	bleeding	NOUN
iajs-1229	31	10	is	be	AUX
iajs-1229	31	11	increased	increase	VERB
iajs-1229	31	12	if	if	SCONJ
iajs-1229	31	13	aspirin	aspirin	NOUN
iajs-1229	31	14	is	be	AUX
iajs-1229	31	15	coadministered	coadministere	VERB
iajs-1229	31	16	,	,	PUNCT
iajs-1229	31	17	it	it	PRON
iajs-1229	31	18	is	be	AUX
iajs-1229	31	19	likely	likely	ADJ
iajs-1229	31	20	that	that	SCONJ
iajs-1229	31	21	a	a	DET
iajs-1229	31	22	high	high	ADJ
iajs-1229	31	23	percentage	percentage	NOUN
iajs-1229	31	24	of	of	ADP
iajs-1229	31	25	patients	patient	NOUN
iajs-1229	31	26	who	who	PRON
iajs-1229	31	27	receive	receive	VERB
iajs-1229	31	28	thrombolytic	thrombolytic	ADJ
iajs-1229	31	29	agents	agent	NOUN
iajs-1229	31	30	will	will	AUX
iajs-1229	31	31	be	be	AUX
iajs-1229	31	32	already	already	ADV
iajs-1229	31	33	receiving	receive	VERB
iajs-1229	31	34	aspirin.(5,6	aspirin.(5,6	NOUN
iajs-1229	31	35	)	)	PUNCT
iajs-1229	31	36	in	in	ADP
iajs-1229	31	37	1970	1970	NUM
iajs-1229	31	38	,	,	PUNCT
iajs-1229	31	39	linus	linus	PROPN
iajs-1229	31	40	pauling	pauling	PROPN
iajs-1229	31	41	wrote	write	VERB
iajs-1229	31	42	a	a	DET
iajs-1229	31	43	book	book	NOUN
iajs-1229	31	44	entitled	entitle	VERB
iajs-1229	31	45	"	"	PUNCT
iajs-1229	31	46	vitamin	vitamin	NOUN
iajs-1229	31	47	c	c	NOUN
iajs-1229	31	48	and	and	CCONJ
iajs-1229	31	49	the	the	DET
iajs-1229	31	50	common	common	ADJ
iajs-1229	31	51	cold	cold	NOUN
iajs-1229	31	52	"	"	PUNCT
iajs-1229	31	53	in	in	ADP
iajs-1229	31	54	which	which	PRON
iajs-1229	31	55	he	he	PRON
iajs-1229	31	56	suggested	suggest	VERB
iajs-1229	31	57	that	that	SCONJ
iajs-1229	31	58	megadoses	megadose	NOUN
iajs-1229	31	59	of	of	ADP
iajs-1229	31	60	vitamin	vitamin	NOUN
iajs-1229	31	61	c	c	NOUN
iajs-1229	31	62	would	would	AUX
iajs-1229	31	63	aid	aid	VERB
iajs-1229	31	64	in	in	ADP
iajs-1229	31	65	the	the	DET
iajs-1229	31	66	prevention	prevention	NOUN
iajs-1229	31	67	of	of	ADP
iajs-1229	31	68	colds	cold	NOUN
iajs-1229	31	69	.	.	PUNCT
iajs-1229	32	1	however	however	ADV
iajs-1229	32	2	,	,	PUNCT
iajs-1229	32	3	subsequent	subsequent	ADJ
iajs-1229	32	4	studies	study	NOUN
iajs-1229	32	5	have	have	AUX
iajs-1229	32	6	shown	show	VERB
iajs-1229	32	7	that	that	SCONJ
iajs-1229	32	8	high	high	ADJ
iajs-1229	32	9	intake	intake	NOUN
iajs-1229	32	10	of	of	ADP
iajs-1229	32	11	vitamin	vitamin	NOUN
iajs-1229	32	12	c	c	NOUN
iajs-1229	32	13	does	do	AUX
iajs-1229	32	14	not	not	PART
iajs-1229	32	15	correspond	correspond	VERB
iajs-1229	32	16	to	to	ADP
iajs-1229	32	17	a	a	DET
iajs-1229	32	18	lower	low	ADJ
iajs-1229	32	19	rate	rate	NOUN
iajs-1229	32	20	of	of	ADP
iajs-1229	32	21	respiratory	respiratory	ADJ
iajs-1229	32	22	viral	viral	ADJ
iajs-1229	32	23	infections.additionally	infections.additionally	NOUN
iajs-1229	32	24	,	,	PUNCT
iajs-1229	32	25	diets	diet	NOUN
iajs-1229	32	26	high	high	ADJ
iajs-1229	32	27	in	in	ADP
iajs-1229	32	28	vitamin	vitamin	NOUN
iajs-1229	32	29	c	c	NOUN
iajs-1229	32	30	were	be	AUX
iajs-1229	32	31	found	find	VERB
iajs-1229	32	32	to	to	PART
iajs-1229	32	33	be	be	AUX
iajs-1229	32	34	detrimental	detrimental	ADJ
iajs-1229	32	35	to	to	ADP
iajs-1229	32	36	a	a	DET
iajs-1229	32	37	persons	person	NOUN
iajs-1229	32	38	health	health	NOUN
iajs-1229	32	39	.	.	PUNCT
iajs-1229	33	1	for	for	ADP
iajs-1229	33	2	example	example	NOUN
iajs-1229	33	3	,	,	PUNCT
iajs-1229	33	4	ascorbic	ascorbic	NOUN
iajs-1229	33	5	acid	acid	NOUN
iajs-1229	33	6	can	can	AUX
iajs-1229	33	7	react	react	VERB
iajs-1229	33	8	with	with	ADP
iajs-1229	33	9	iron	iron	NOUN
iajs-1229	33	10	ions	ion	NOUN
iajs-1229	33	11	to	to	PART
iajs-1229	33	12	produce	produce	VERB
iajs-1229	33	13	hydroxy	hydroxy	ADJ
iajs-1229	33	14	radicals	radical	NOUN
iajs-1229	33	15	,	,	PUNCT
iajs-1229	33	16	which	which	PRON
iajs-1229	33	17	leads	lead	VERB
iajs-1229	33	18	to	to	ADP
iajs-1229	33	19	cellular	cellular	ADJ
iajs-1229	33	20	damage	damage	NOUN
iajs-1229	33	21	.	.	PUNCT
iajs-1229	34	1	in	in	ADP
iajs-1229	34	2	addition	addition	NOUN
iajs-1229	34	3	,	,	PUNCT
iajs-1229	34	4	a	a	DET
iajs-1229	34	5	condition	condition	NOUN
iajs-1229	34	6	called	call	VERB
iajs-1229	34	7	withdrawal	withdrawal	NOUN
iajs-1229	34	8	scurvy	scurvy	NOUN
iajs-1229	34	9	is	be	AUX
iajs-1229	34	10	associated	associate	VERB
iajs-1229	34	11	with	with	ADP
iajs-1229	34	12	megadoses	megadose	NOUN
iajs-1229	34	13	of	of	ADP
iajs-1229	34	14	vitamin	vitamin	NOUN
iajs-1229	34	15	c(7,8	c(7,8	NOUN
iajs-1229	34	16	)	)	PUNCT
iajs-1229	34	17	.	.	PUNCT
iajs-1229	35	1	this	this	DET
iajs-1229	35	2	condition	condition	NOUN
iajs-1229	35	3	is	be	AUX
iajs-1229	35	4	observed	observe	VERB
iajs-1229	35	5	with	with	ADP
iajs-1229	35	6	a	a	DET
iajs-1229	35	7	high	high	ADJ
iajs-1229	35	8	ascorbic	ascorbic	NOUN
iajs-1229	35	9	acid	acid	NOUN
iajs-1229	35	10	diet	diet	NOUN
iajs-1229	35	11	,	,	PUNCT
iajs-1229	35	12	when	when	SCONJ
iajs-1229	35	13	the	the	DET
iajs-1229	35	14	body	body	NOUN
iajs-1229	35	15	begins	begin	VERB
iajs-1229	35	16	to	to	PART
iajs-1229	35	17	excrete	excrete	VERB
iajs-1229	35	18	the	the	DET
iajs-1229	35	19	excess	excess	ADJ
iajs-1229	35	20	vitamin	vitamin	NOUN
iajs-1229	35	21	c	c	NOUN
iajs-1229	35	22	at	at	ADP
iajs-1229	35	23	a	a	DET
iajs-1229	35	24	common	common	ADJ
iajs-1229	35	25	rate	rate	NOUN
iajs-1229	35	26	.	.	PUNCT
iajs-1229	36	1	when	when	SCONJ
iajs-1229	36	2	the	the	DET
iajs-1229	36	3	intake	intake	NOUN
iajs-1229	36	4	of	of	ADP
iajs-1229	36	5	vitamin	vitamin	NOUN
iajs-1229	36	6	c	c	NOUN
iajs-1229	36	7	is	be	AUX
iajs-1229	36	8	decreased	decrease	VERB
iajs-1229	36	9	,	,	PUNCT
iajs-1229	36	10	the	the	DET
iajs-1229	36	11	excretion	excretion	NOUN
iajs-1229	36	12	rate	rate	NOUN
iajs-1229	36	13	from	from	ADP
iajs-1229	36	14	before	before	ADV
iajs-1229	36	15	continues	continue	VERB
iajs-1229	36	16	at	at	ADP
iajs-1229	36	17	the	the	DET
iajs-1229	36	18	same	same	ADJ
iajs-1229	36	19	rate	rate	NOUN
iajs-1229	36	20	,	,	PUNCT
iajs-1229	36	21	eliminating	eliminate	VERB
iajs-1229	36	22	the	the	DET
iajs-1229	36	23	lower	low	ADJ
iajs-1229	36	24	dosage	dosage	NOUN
iajs-1229	36	25	amount	amount	NOUN
iajs-1229	36	26	at	at	ADP
iajs-1229	36	27	a	a	DET
iajs-1229	36	28	high	high	ADJ
iajs-1229	36	29	rate	rate	NOUN
iajs-1229	36	30	.	.	PUNCT
iajs-1229	37	1	therefore	therefore	ADV
iajs-1229	37	2	,	,	PUNCT
iajs-1229	37	3	people	people	NOUN
iajs-1229	37	4	begin	begin	VERB
iajs-1229	37	5	to	to	PART
iajs-1229	37	6	exhibit	exhibit	VERB
iajs-1229	37	7	signs	sign	NOUN
iajs-1229	37	8	of	of	ADP
iajs-1229	37	9	scurvy	scurvy	NOUN
iajs-1229	37	10	due	due	ADP
iajs-1229	37	11	to	to	ADP
iajs-1229	37	12	this	this	DET
iajs-1229	37	13	phenomenon	phenomenon	NOUN
iajs-1229	37	14	.	.	PUNCT
iajs-1229	38	1	another	another	DET
iajs-1229	38	2	side	side	ADJ
iajs-1229	38	3	effect	effect	NOUN
iajs-1229	38	4	from	from	ADP
iajs-1229	38	5	megadoses	megadose	NOUN
iajs-1229	38	6	of	of	ADP
iajs-1229	38	7	vitamin	vitamin	NOUN
iajs-1229	38	8	c	c	NOUN
iajs-1229	38	9	is	be	AUX
iajs-1229	38	10	the	the	DET
iajs-1229	38	11	formation	formation	NOUN
iajs-1229	38	12	of	of	ADP
iajs-1229	38	13	kidney	kidney	NOUN
iajs-1229	38	14	stones	stone	NOUN
iajs-1229	38	15	from	from	ADP
iajs-1229	38	16	the	the	DET
iajs-1229	38	17	buildup	buildup	NOUN
iajs-1229	38	18	of	of	ADP
iajs-1229	38	19	oxalic	oxalic	NOUN
iajs-1229	38	20	acid	acid	NOUN
iajs-1229	38	21	and	and	CCONJ
iajs-1229	38	22	uric	uric	ADJ
iajs-1229	38	23	acid(9,10	acid(9,10	NOUN
iajs-1229	38	24	)	)	PUNCT
iajs-1229	38	25	.	.	PUNCT
iajs-1229	39	1	a	a	DET
iajs-1229	39	2	final	final	ADJ
iajs-1229	39	3	negative	negative	ADJ
iajs-1229	39	4	side	side	NOUN
iajs-1229	39	5	effect	effect	NOUN
iajs-1229	39	6	is	be	AUX
iajs-1229	39	7	the	the	DET
iajs-1229	39	8	experiencing	experiencing	NOUN
iajs-1229	39	9	of	of	ADP
iajs-1229	39	10	diarrhea	diarrhea	NOUN
iajs-1229	39	11	and	and	CCONJ
iajs-1229	39	12	skin	skin	NOUN
iajs-1229	39	13	rashes	rash	NOUN
iajs-1229	39	14	,	,	PUNCT
iajs-1229	39	15	if	if	SCONJ
iajs-1229	39	16	the	the	DET
iajs-1229	39	17	megadoses	megadose	NOUN
iajs-1229	39	18	are	be	AUX
iajs-1229	39	19	taken	take	VERB
iajs-1229	39	20	suddenly	suddenly	ADV
iajs-1229	39	21	in	in	ADP
iajs-1229	39	22	large	large	ADJ
iajs-1229	39	23	amounts	amount	NOUN
iajs-1229	39	24	without	without	ADP
iajs-1229	39	25	allowing	allow	VERB
iajs-1229	39	26	the	the	DET
iajs-1229	39	27	body	body	NOUN
iajs-1229	39	28	to	to	PART
iajs-1229	39	29	adjust	adjust	VERB
iajs-1229	39	30	to	to	ADP
iajs-1229	39	31	the	the	DET
iajs-1229	39	32	high	high	ADJ
iajs-1229	39	33	concentrations	concentration	NOUN
iajs-1229	39	34	by	by	ADP
iajs-1229	39	35	taking	take	VERB
iajs-1229	39	36	slowly	slowly	ADV
iajs-1229	39	37	increasing	increase	VERB
iajs-1229	39	38	amounts	amount	NOUN
iajs-1229	39	39	.	.	PUNCT
iajs-1229	40	1	experimental	experimental	ADJ
iajs-1229	40	2	compounds	compound	NOUN
iajs-1229	40	3	3-(acetyl	3-(acetyl	NUM
iajs-1229	40	4	salicyloyl)-5,6	salicyloyl)-5,6	ADJ
iajs-1229	40	5	–	–	PUNCT
iajs-1229	40	6	o	o	NOUN
iajs-1229	40	7	-	-	PUNCT
iajs-1229	40	8	isopropylidene	isopropylidene	ADJ
iajs-1229	40	9	-	-	PUNCT
iajs-1229	40	10	l	l	NOUN
iajs-1229	40	11	-	-	ADJ
iajs-1229	40	12	ascorbic	ascorbic	ADJ
iajs-1229	40	13	acid	acid	NOUN
iajs-1229	40	14	(	(	PUNCT
iajs-1229	40	15	1	1	NUM
iajs-1229	40	16	)	)	PUNCT
iajs-1229	40	17	,	,	PUNCT
iajs-1229	40	18	2,3di(acetyl	2,3di(acetyl	NUM
iajs-1229	40	19	salicyloyl)-5,6	salicyloyl)-5,6	ADJ
iajs-1229	40	20	–	–	PUNCT
iajs-1229	40	21	o	o	NOUN
iajs-1229	40	22	-	-	PUNCT
iajs-1229	40	23	isopropylidene	isopropylidene	ADJ
iajs-1229	40	24	-	-	PUNCT
iajs-1229	40	25	l	l	NOUN
iajs-1229	40	26	-	-	ADJ
iajs-1229	40	27	ascorbic	ascorbic	ADJ
iajs-1229	40	28	acid	acid	NOUN
iajs-1229	40	29	(	(	PUNCT
iajs-1229	40	30	2	2	NUM
iajs-1229	40	31	)	)	PUNCT
iajs-1229	40	32	and	and	CCONJ
iajs-1229	40	33	2,3,5,6	2,3,5,6	NUM
iajs-1229	40	34	-	-	SYM
iajs-1229	40	35	tetra(acetyl	tetra(acetyl	VERB
iajs-1229	40	36	salicyloyl)-l	salicyloyl)-l	NOUN
iajs-1229	40	37	-	-	PUNCT
iajs-1229	40	38	ascorbic	ascorbic	NOUN
iajs-1229	40	39	acid	acid	NOUN
iajs-1229	40	40	(	(	PUNCT
iajs-1229	40	41	3	3	NUM
iajs-1229	40	42	)	)	PUNCT
iajs-1229	40	43	were	be	AUX
iajs-1229	40	44	synthesis	synthesis	NOUN
iajs-1229	40	45	and	and	CCONJ
iajs-1229	40	46	identification	identification	NOUN
iajs-1229	40	47	according	accord	VERB
iajs-1229	40	48	to	to	ADP
iajs-1229	40	49	the	the	DET
iajs-1229	40	50	literature(11,12,13	literature(11,12,13	NOUN
iajs-1229	40	51	)	)	PUNCT
iajs-1229	40	52	three	three	NUM
iajs-1229	40	53	individuals	individual	NOUN
iajs-1229	40	54	of	of	ADP
iajs-1229	40	55	english	english	ADJ
iajs-1229	40	56	angora	angora	PROPN
iajs-1229	40	57	rabbits	rabbit	NOUN
iajs-1229	40	58	weighing	weigh	VERB
iajs-1229	40	59	(	(	PUNCT
iajs-1229	40	60	1.80,1.92,2.1	1.80,1.92,2.1	NUM
iajs-1229	40	61	)	)	PUNCT
iajs-1229	40	62	kg	kg	NOUN
iajs-1229	40	63	were	be	AUX
iajs-1229	40	64	fasted	fast	VERB
iajs-1229	40	65	for	for	ADP
iajs-1229	40	66	48	48	NUM
iajs-1229	40	67	hrs	hrs	NOUN
iajs-1229	40	68	.	.	PUNCT
iajs-1229	41	1	prior	prior	ADV
iajs-1229	41	2	to	to	ADP
iajs-1229	41	3	drug	drug	NOUN
iajs-1229	41	4	administration	administration	NOUN
iajs-1229	41	5	with	with	ADP
iajs-1229	41	6	free	free	ADJ
iajs-1229	41	7	access	access	NOUN
iajs-1229	41	8	to	to	ADP
iajs-1229	41	9	drinking	drinking	NOUN
iajs-1229	41	10	water	water	NOUN
iajs-1229	41	11	.	.	PUNCT
iajs-1229	42	1	each	each	DET
iajs-1229	42	2	single	single	ADJ
iajs-1229	42	3	rabbit	rabbit	NOUN
iajs-1229	42	4	forced	force	VERB
iajs-1229	42	5	fed	fed	PROPN
iajs-1229	42	6	1.5	1.5	NUM
iajs-1229	42	7	g	g	NOUN
iajs-1229	42	8	of	of	ADP
iajs-1229	42	9	tested	test	VERB
iajs-1229	42	10	drug	drug	NOUN
iajs-1229	42	11	(	(	PUNCT
iajs-1229	42	12	3-(acetyl	3-(acetyl	NUM
iajs-1229	42	13	salicyloyl)-5,6	salicyloyl)-5,6	NOUN
iajs-1229	42	14	–	–	PUNCT
iajs-1229	42	15	o	o	NOUN
iajs-1229	42	16	-	-	PUNCT
iajs-1229	42	17	isopropylidene	isopropylidene	ADJ
iajs-1229	42	18	-	-	PUNCT
iajs-1229	42	19	l	l	NOUN
iajs-1229	42	20	-	-	NOUN
iajs-1229	42	21	ascorbic	ascorbic	NOUN
iajs-1229	42	22	acid(1	acid(1	NOUN
iajs-1229	42	23	)	)	PUNCT
iajs-1229	42	24	,	,	PUNCT
iajs-1229	42	25	2,3(acetyl	2,3(acetyl	NUM
iajs-1229	42	26	salicyloyl)-5,6	salicyloyl)-5,6	NOUN
iajs-1229	42	27	–	–	PUNCT
iajs-1229	42	28	o	o	NOUN
iajs-1229	42	29	-	-	PUNCT
iajs-1229	42	30	isopropylidene	isopropylidene	ADJ
iajs-1229	42	31	-	-	PUNCT
iajs-1229	42	32	l	l	NOUN
iajs-1229	42	33	-	-	ADJ
iajs-1229	42	34	ascorbic	ascorbic	ADJ
iajs-1229	42	35	acid(2	acid(2	NOUN
iajs-1229	42	36	)	)	PUNCT
iajs-1229	42	37	and	and	CCONJ
iajs-1229	42	38	2,3,5,6-(acetyl	2,3,5,6-(acetyl	NUM
iajs-1229	42	39	salicyloyl)-l	salicyloyl)-l	NOUN
iajs-1229	42	40	-	-	PUNCT
iajs-1229	42	41	ascorbic	ascorbic	NOUN
iajs-1229	42	42	acid(3	acid(3	NOUN
iajs-1229	42	43	)	)	PUNCT
iajs-1229	42	44	)	)	PUNCT
iajs-1229	42	45	;	;	PUNCT
iajs-1229	42	46	the	the	DET
iajs-1229	42	47	drug	drug	NOUN
iajs-1229	42	48	introduced	introduce	VERB
iajs-1229	42	49	by	by	ADP
iajs-1229	42	50	a	a	DET
iajs-1229	42	51	pice	pice	NOUN
iajs-1229	42	52	of	of	ADP
iajs-1229	42	53	cucumber	cucumber	NOUN
iajs-1229	42	54	contaminated	contaminate	VERB
iajs-1229	42	55	with	with	ADP
iajs-1229	42	56	a	a	DET
iajs-1229	42	57	tested	test	VERB
iajs-1229	42	58	dose	dose	NOUN
iajs-1229	42	59	.	.	PUNCT
iajs-1229	43	1	blood	blood	NOUN
iajs-1229	43	2	samples	sample	NOUN
iajs-1229	43	3	were	be	AUX
iajs-1229	43	4	collected	collect	VERB
iajs-1229	43	5	after	after	ADP
iajs-1229	43	6	and	and	CCONJ
iajs-1229	43	7	before	before	ADP
iajs-1229	43	8	the	the	DET
iajs-1229	43	9	drug	drug	NOUN
iajs-1229	43	10	administration	administration	NOUN
iajs-1229	43	11	at	at	ADP
iajs-1229	43	12	different	different	ADJ
iajs-1229	43	13	intervals	interval	NOUN
iajs-1229	43	14	of	of	ADP
iajs-1229	43	15	time	time	NOUN
iajs-1229	43	16	(	(	PUNCT
iajs-1229	43	17	0,2,3,4,6,8,10	0,2,3,4,6,8,10	NUM
iajs-1229	43	18	hr	hr	NOUN
iajs-1229	43	19	.	.	PUNCT
iajs-1229	43	20	)	)	PUNCT
iajs-1229	44	1	the	the	DET
iajs-1229	44	2	blood	blood	NOUN
iajs-1229	44	3	was	be	AUX
iajs-1229	44	4	left	leave	VERB
iajs-1229	44	5	at	at	ADP
iajs-1229	44	6	room	room	NOUN
iajs-1229	44	7	temperature	temperature	NOUN
iajs-1229	44	8	for	for	ADP
iajs-1229	44	9	about	about	ADV
iajs-1229	44	10	half	half	DET
iajs-1229	44	11	an	an	DET
iajs-1229	44	12	hour	hour	NOUN
iajs-1229	44	13	then	then	ADV
iajs-1229	44	14	the	the	DET
iajs-1229	44	15	serum	serum	NOUN
iajs-1229	44	16	was	be	AUX
iajs-1229	44	17	separated	separate	VERB
iajs-1229	44	18	by	by	ADP
iajs-1229	44	19	centrifuging	centrifuge	VERB
iajs-1229	44	20	for	for	ADP
iajs-1229	44	21	15	15	NUM
iajs-1229	44	22	minutes	minute	NOUN
iajs-1229	44	23	at	at	ADP
iajs-1229	44	24	3500	3500	NUM
iajs-1229	44	25	rpm	rpm	NOUN
iajs-1229	44	26	.	.	PUNCT
iajs-1229	45	1	and	and	CCONJ
iajs-1229	45	2	stored	store	VERB
iajs-1229	45	3	at	at	ADP
iajs-1229	45	4	-20	-20	NUM
iajs-1229	45	5	o	o	NOUN
iajs-1229	45	6	c	c	NOUN
iajs-1229	45	7	until	until	SCONJ
iajs-1229	45	8	analysis	analysis	NOUN
iajs-1229	45	9	was	be	AUX
iajs-1229	45	10	performed	perform	VERB
iajs-1229	45	11	.	.	PUNCT
iajs-1229	46	1	the	the	DET
iajs-1229	46	2	concentration	concentration	NOUN
iajs-1229	46	3	of	of	ADP
iajs-1229	46	4	aspirin	aspirin	NOUN
iajs-1229	46	5	was	be	AUX
iajs-1229	46	6	followed	follow	VERB
iajs-1229	46	7	at	at	ADP
iajs-1229	46	8	fixed	fix	VERB
iajs-1229	46	9	wave	wave	NOUN
iajs-1229	46	10	length	length	NOUN
iajs-1229	46	11	at	at	ADP
iajs-1229	46	12	277	277	NUM
iajs-1229	46	13	nm(14	nm(14	NOUN
iajs-1229	46	14	)	)	PUNCT
iajs-1229	46	15	.	.	PUNCT
iajs-1229	47	1	result	result	NOUN
iajs-1229	47	2	and	and	CCONJ
iajs-1229	47	3	discussion	discussion	NOUN
iajs-1229	47	4	in	in	ADP
iajs-1229	47	5	this	this	DET
iajs-1229	47	6	study	study	NOUN
iajs-1229	47	7	1.5	1.5	NUM
iajs-1229	47	8	gm	gm	NOUN
iajs-1229	47	9	the	the	DET
iajs-1229	47	10	compounds	compound	NOUN
iajs-1229	47	11	(	(	PUNCT
iajs-1229	47	12	1),(2),(3	1),(2),(3	NOUN
iajs-1229	47	13	)	)	PUNCT
iajs-1229	47	14	were	be	AUX
iajs-1229	47	15	used	use	VERB
iajs-1229	47	16	(	(	PUNCT
iajs-1229	47	17	oral	oral	ADJ
iajs-1229	47	18	administration	administration	NOUN
iajs-1229	47	19	to	to	ADP
iajs-1229	47	20	a	a	DET
iajs-1229	47	21	group	group	NOUN
iajs-1229	47	22	of	of	ADP
iajs-1229	47	23	three	three	NUM
iajs-1229	47	24	rabbits	rabbit	NOUN
iajs-1229	47	25	)	)	PUNCT
iajs-1229	47	26	.	.	PUNCT
iajs-1229	48	1	blood	blood	NOUN
iajs-1229	48	2	sample	sample	NOUN
iajs-1229	48	3	was	be	AUX
iajs-1229	48	4	taken	take	VERB
iajs-1229	48	5	from	from	ADP
iajs-1229	48	6	the	the	DET
iajs-1229	48	7	rabbits	rabbit	NOUN
iajs-1229	48	8	then	then	ADV
iajs-1229	48	9	the	the	DET
iajs-1229	48	10	serum	serum	NOUN
iajs-1229	48	11	was	be	AUX
iajs-1229	48	12	separated	separate	VERB
iajs-1229	48	13	by	by	ADP
iajs-1229	48	14	centrifuge,150	centrifuge,150	PROPN
iajs-1229	48	15	µl	µl	ADP
iajs-1229	48	16	from	from	ADP
iajs-1229	48	17	serum	serum	NOUN
iajs-1229	48	18	was	be	AUX
iajs-1229	48	19	diluted	dilute	VERB
iajs-1229	48	20	with	with	ADP
iajs-1229	48	21	methanol	methanol	NOUN
iajs-1229	48	22	(	(	PUNCT
iajs-1229	48	23	25	25	NUM
iajs-1229	48	24	ml	ml	NOUN
iajs-1229	48	25	)	)	PUNCT
iajs-1229	48	26	.the	.the	DET
iajs-1229	48	27	aspirin	aspirin	NOUN
iajs-1229	48	28	concentration	concentration	NOUN
iajs-1229	48	29	was	be	AUX
iajs-1229	48	30	measured	measure	VERB
iajs-1229	48	31	in	in	ADP
iajs-1229	48	32	serum	serum	NOUN
iajs-1229	48	33	at	at	ADP
iajs-1229	48	34	277	277	NUM
iajs-1229	48	35	nm	nm	NOUN
iajs-1229	48	36	.	.	PUNCT
iajs-1229	49	1	-the	-the	DET
iajs-1229	49	2	aspirin	aspirin	NOUN
iajs-1229	49	3	concentration	concentration	NOUN
iajs-1229	49	4	after	after	ADP
iajs-1229	49	5	(	(	PUNCT
iajs-1229	49	6	2	2	NUM
iajs-1229	49	7	hr	hr	NOUN
iajs-1229	49	8	.	.	PUNCT
iajs-1229	49	9	)	)	PUNCT
iajs-1229	49	10	was	be	AUX
iajs-1229	49	11	(	(	PUNCT
iajs-1229	49	12	3.71x10	3.71x10	NUM
iajs-1229	49	13	-5	-5	VERB
iajs-1229	49	14	m	m	NOUN
iajs-1229	49	15	)	)	PUNCT
iajs-1229	49	16	,	,	PUNCT
iajs-1229	49	17	(	(	PUNCT
iajs-1229	49	18	3	3	NUM
iajs-1229	49	19	hr	hr	NOUN
iajs-1229	49	20	.	.	PUNCT
iajs-1229	49	21	)	)	PUNCT
iajs-1229	50	1	was	be	AUX
iajs-1229	50	2	(	(	PUNCT
iajs-1229	50	3	3.2x10	3.2x10	NUM
iajs-1229	50	4	-3	-3	INTJ
iajs-1229	50	5	m	m	PROPN
iajs-1229	50	6	)	)	PUNCT
iajs-1229	50	7	,	,	PUNCT
iajs-1229	50	8	(	(	PUNCT
iajs-1229	50	9	4	4	NUM
iajs-1229	50	10	hr	hr	NOUN
iajs-1229	50	11	.	.	PUNCT
iajs-1229	50	12	)	)	PUNCT
iajs-1229	51	1	was	be	AUX
iajs-1229	51	2	(	(	PUNCT
iajs-1229	51	3	4.08x10	4.08x10	NUM
iajs-1229	51	4	-3	-3	ADJ
iajs-1229	51	5	m	m	PROPN
iajs-1229	51	6	)	)	PUNCT
iajs-1229	51	7	,	,	PUNCT
iajs-1229	51	8	(	(	PUNCT
iajs-1229	51	9	6	6	NUM
iajs-1229	51	10	hr	hr	NOUN
iajs-1229	51	11	.	.	PUNCT
iajs-1229	51	12	)	)	PUNCT
iajs-1229	52	1	was	be	AUX
iajs-1229	52	2	(	(	PUNCT
iajs-1229	52	3	3.41x10	3.41x10	NUM
iajs-1229	52	4	-3	-3	PUNCT
iajs-1229	52	5	)	)	PUNCT
iajs-1229	52	6	,	,	PUNCT
iajs-1229	52	7	(	(	PUNCT
iajs-1229	52	8	8	8	NUM
iajs-1229	52	9	hr	hr	NOUN
iajs-1229	52	10	.	.	PUNCT
iajs-1229	52	11	)	)	PUNCT
iajs-1229	53	1	was	be	AUX
iajs-1229	53	2	(	(	PUNCT
iajs-1229	53	3	4.61x10	4.61x10	X
iajs-1229	53	4	-3	-3	X
iajs-1229	53	5	m	m	PROPN
iajs-1229	53	6	)	)	PUNCT
iajs-1229	53	7	,	,	PUNCT
iajs-1229	53	8	(	(	PUNCT
iajs-1229	53	9	10	10	NUM
iajs-1229	53	10	hr	hr	NOUN
iajs-1229	53	11	.	.	PUNCT
iajs-1229	53	12	)	)	PUNCT
iajs-1229	54	1	was	be	AUX
iajs-1229	54	2	(	(	PUNCT
iajs-1229	54	3	3.601	3.601	NUM
iajs-1229	54	4	x10	x10	NOUN
iajs-1229	54	5	-5	-5	VERB
iajs-1229	54	6	m	m	VERB
iajs-1229	54	7	)	)	PUNCT
iajs-1229	54	8	for	for	ADP
iajs-1229	54	9	the	the	DET
iajs-1229	54	10	compound	compound	NOUN
iajs-1229	54	11	(	(	PUNCT
iajs-1229	54	12	1	1	NUM
iajs-1229	54	13	)	)	PUNCT
iajs-1229	54	14	.	.	PUNCT
iajs-1229	55	1	ibn	ibn	PROPN
iajs-1229	55	2	alhaitham	alhaitham	PROPN
iajs-1229	55	3	j.	j.	PROPN
iajs-1229	55	4	for	for	ADP
iajs-1229	55	5	pure	pure	ADJ
iajs-1229	55	6	&	&	CCONJ
iajs-1229	55	7	appl	appl	PROPN
iajs-1229	55	8	.	.	PUNCT
iajs-1229	56	1	sci	sci	PROPN
iajs-1229	56	2	vol.22	vol.22	PROPN
iajs-1229	56	3	(	(	PUNCT
iajs-1229	56	4	2	2	NUM
iajs-1229	56	5	)	)	PUNCT
iajs-1229	56	6	2009	2009	NUM
iajs-1229	56	7	http://www.gfhnrc.ars.usda.gov/pubs/pub0911.htm	http://www.gfhnrc.ars.usda.gov/pubs/pub0911.htm	NUM
iajs-1229	57	1	http://www.healthanswers.com/database/ami/converted/000355.html	http://www.healthanswers.com/database/ami/converted/000355.html	PROPN
iajs-1229	57	2	http://www.healthanswers.com/database/ami/converted/000355.html	http://www.healthanswers.com/database/ami/converted/000355.html	PROPN
iajs-1229	57	3	http://www.lgcy.com/users/h/health&wealth/c.html	http://www.lgcy.com/users/h/health&wealth/c.html	PUNCT
iajs-1229	57	4	http://pulsar.cs.wku.edu/~travibr/kidney.html	http://pulsar.cs.wku.edu/~travibr/kidney.html	PROPN
iajs-1229	57	5	-the	-the	DET
iajs-1229	57	6	aspirin	aspirin	NOUN
iajs-1229	57	7	concentration	concentration	NOUN
iajs-1229	57	8	after	after	ADP
iajs-1229	57	9	(	(	PUNCT
iajs-1229	57	10	2	2	NUM
iajs-1229	57	11	hr	hr	NOUN
iajs-1229	57	12	.	.	PUNCT
iajs-1229	57	13	)	)	PUNCT
iajs-1229	58	1	was	be	AUX
iajs-1229	58	2	(	(	PUNCT
iajs-1229	58	3	7.52x10	7.52x10	NUM
iajs-1229	58	4	-5	-5	NOUN
iajs-1229	58	5	m	m	NOUN
iajs-1229	58	6	)	)	PUNCT
iajs-1229	58	7	,	,	PUNCT
iajs-1229	58	8	(	(	PUNCT
iajs-1229	58	9	3	3	NUM
iajs-1229	58	10	hr	hr	NOUN
iajs-1229	58	11	.	.	PUNCT
iajs-1229	58	12	)	)	PUNCT
iajs-1229	59	1	was	be	AUX
iajs-1229	59	2	(	(	PUNCT
iajs-1229	59	3	6.40x10	6.40x10	X
iajs-1229	59	4	-3	-3	NOUN
iajs-1229	59	5	m	m	PROPN
iajs-1229	59	6	)	)	PUNCT
iajs-1229	59	7	,	,	PUNCT
iajs-1229	59	8	(	(	PUNCT
iajs-1229	59	9	4	4	NUM
iajs-1229	59	10	hr	hr	NOUN
iajs-1229	59	11	.	.	PUNCT
iajs-1229	59	12	)	)	PUNCT
iajs-1229	60	1	was	be	AUX
iajs-1229	60	2	(	(	PUNCT
iajs-1229	60	3	8.38x10	8.38x10	NUM
iajs-1229	60	4	-3	-3	X
iajs-1229	60	5	m	m	PROPN
iajs-1229	60	6	)	)	PUNCT
iajs-1229	60	7	,	,	PUNCT
iajs-1229	60	8	(	(	PUNCT
iajs-1229	60	9	6	6	NUM
iajs-1229	60	10	hr	hr	NOUN
iajs-1229	60	11	.	.	PUNCT
iajs-1229	60	12	)	)	PUNCT
iajs-1229	61	1	was	be	AUX
iajs-1229	61	2	(	(	PUNCT
iajs-1229	61	3	6.68x10	6.68x10	NUM
iajs-1229	61	4	-3	-3	SYM
iajs-1229	61	5	m	m	PROPN
iajs-1229	61	6	)	)	PUNCT
iajs-1229	61	7	,	,	PUNCT
iajs-1229	61	8	(	(	PUNCT
iajs-1229	61	9	8	8	NUM
iajs-1229	61	10	hr	hr	NOUN
iajs-1229	61	11	.	.	PUNCT
iajs-1229	61	12	)	)	PUNCT
iajs-1229	62	1	was	be	AUX
iajs-1229	62	2	(	(	PUNCT
iajs-1229	62	3	9.18x10	9.18x10	NUM
iajs-1229	62	4	-4	-4	INTJ
iajs-1229	62	5	m	m	PROPN
iajs-1229	62	6	)	)	PUNCT
iajs-1229	62	7	,	,	PUNCT
iajs-1229	62	8	(	(	PUNCT
iajs-1229	62	9	10	10	NUM
iajs-1229	62	10	hr	hr	NOUN
iajs-1229	62	11	.	.	PUNCT
iajs-1229	62	12	)	)	PUNCT
iajs-1229	63	1	was	be	AUX
iajs-1229	63	2	(	(	PUNCT
iajs-1229	63	3	7.25x10	7.25x10	NUM
iajs-1229	63	4	-5	-5	VERB
iajs-1229	63	5	m	m	VERB
iajs-1229	63	6	)	)	PUNCT
iajs-1229	63	7	for	for	ADP
iajs-1229	63	8	the	the	DET
iajs-1229	63	9	compound	compound	NOUN
iajs-1229	63	10	(	(	PUNCT
iajs-1229	63	11	2	2	NUM
iajs-1229	63	12	)	)	PUNCT
iajs-1229	63	13	.	.	PUNCT
iajs-1229	64	1	-the	-the	DET
iajs-1229	64	2	aspirin	aspirin	NOUN
iajs-1229	64	3	concentration	concentration	NOUN
iajs-1229	64	4	after	after	ADP
iajs-1229	64	5	(	(	PUNCT
iajs-1229	64	6	2	2	NUM
iajs-1229	64	7	hr	hr	NOUN
iajs-1229	64	8	.	.	PUNCT
iajs-1229	64	9	)	)	PUNCT
iajs-1229	64	10	was	be	AUX
iajs-1229	64	11	(	(	PUNCT
iajs-1229	64	12	1.47x10	1.47x10	NUM
iajs-1229	64	13	-4	-4	X
iajs-1229	64	14	m	m	PROPN
iajs-1229	64	15	)	)	PUNCT
iajs-1229	64	16	,	,	PUNCT
iajs-1229	64	17	(	(	PUNCT
iajs-1229	64	18	3	3	NUM
iajs-1229	64	19	hr	hr	NOUN
iajs-1229	64	20	.	.	PUNCT
iajs-1229	64	21	)	)	PUNCT
iajs-1229	64	22	was	be	AUX
iajs-1229	64	23	(	(	PUNCT
iajs-1229	64	24	1.27x10	1.27x10	NUM
iajs-1229	64	25	-2	-2	NOUN
iajs-1229	64	26	m	m	PROPN
iajs-1229	64	27	)	)	PUNCT
iajs-1229	64	28	,	,	PUNCT
iajs-1229	64	29	(	(	PUNCT
iajs-1229	64	30	4	4	NUM
iajs-1229	64	31	hr	hr	NOUN
iajs-1229	64	32	.	.	PUNCT
iajs-1229	64	33	)	)	PUNCT
iajs-1229	65	1	was	be	AUX
iajs-1229	65	2	(	(	PUNCT
iajs-1229	65	3	1.68x10	1.68x10	NUM
iajs-1229	65	4	-2	-2	NOUN
iajs-1229	65	5	m	m	PROPN
iajs-1229	65	6	)	)	PUNCT
iajs-1229	65	7	,	,	PUNCT
iajs-1229	65	8	(	(	PUNCT
iajs-1229	65	9	6	6	NUM
iajs-1229	65	10	hr	hr	NOUN
iajs-1229	65	11	.	.	PUNCT
iajs-1229	65	12	)	)	PUNCT
iajs-1229	66	1	was	be	AUX
iajs-1229	66	2	(	(	PUNCT
iajs-1229	66	3	1.34x10	1.34x10	NUM
iajs-1229	66	4	-2	-2	NOUN
iajs-1229	66	5	m	m	PROPN
iajs-1229	66	6	)	)	PUNCT
iajs-1229	66	7	,	,	PUNCT
iajs-1229	66	8	(	(	PUNCT
iajs-1229	66	9	8	8	NUM
iajs-1229	66	10	hr	hr	NOUN
iajs-1229	66	11	.	.	PUNCT
iajs-1229	66	12	)	)	PUNCT
iajs-1229	67	1	was	be	AUX
iajs-1229	67	2	(	(	PUNCT
iajs-1229	67	3	1.84x10	1.84x10	NUM
iajs-1229	67	4	-3	-3	INTJ
iajs-1229	67	5	m	m	PROPN
iajs-1229	67	6	)	)	PUNCT
iajs-1229	67	7	,	,	PUNCT
iajs-1229	67	8	(	(	PUNCT
iajs-1229	67	9	10	10	NUM
iajs-1229	67	10	hr	hr	NOUN
iajs-1229	67	11	.	.	PUNCT
iajs-1229	67	12	)	)	PUNCT
iajs-1229	68	1	was	be	AUX
iajs-1229	68	2	(	(	PUNCT
iajs-1229	68	3	1.46x10	1.46x10	NUM
iajs-1229	68	4	-4	-4	NOUN
iajs-1229	68	5	m	m	NOUN
iajs-1229	68	6	)	)	PUNCT
iajs-1229	68	7	for	for	ADP
iajs-1229	68	8	the	the	DET
iajs-1229	68	9	compound	compound	NOUN
iajs-1229	68	10	(	(	PUNCT
iajs-1229	68	11	3	3	NUM
iajs-1229	68	12	)	)	PUNCT
iajs-1229	68	13	.table	.table	NOUN
iajs-1229	68	14	(	(	PUNCT
iajs-1229	68	15	1	1	NUM
iajs-1229	68	16	-	-	SYM
iajs-1229	68	17	3	3	NUM
iajs-1229	68	18	)	)	PUNCT
iajs-1229	68	19	,	,	PUNCT
iajs-1229	68	20	figure	figure	NOUN
iajs-1229	68	21	(	(	PUNCT
iajs-1229	68	22	1	1	NUM
iajs-1229	68	23	-	-	SYM
iajs-1229	68	24	3	3	NUM
iajs-1229	68	25	)	)	PUNCT
iajs-1229	68	26	the	the	DET
iajs-1229	68	27	results	result	NOUN
iajs-1229	68	28	show	show	VERB
iajs-1229	68	29	that	that	SCONJ
iajs-1229	68	30	the	the	DET
iajs-1229	68	31	concentration	concentration	NOUN
iajs-1229	68	32	of	of	ADP
iajs-1229	68	33	aspirin	aspirin	NOUN
iajs-1229	68	34	was	be	AUX
iajs-1229	68	35	low	low	ADJ
iajs-1229	68	36	in	in	ADP
iajs-1229	68	37	the	the	DET
iajs-1229	68	38	first	first	ADJ
iajs-1229	68	39	hour	hour	NOUN
iajs-1229	68	40	and	and	CCONJ
iajs-1229	68	41	then	then	ADV
iajs-1229	68	42	increased	increase	VERB
iajs-1229	68	43	with	with	ADP
iajs-1229	68	44	time	time	NOUN
iajs-1229	68	45	increased	increase	VERB
iajs-1229	68	46	until	until	ADP
iajs-1229	68	47	4	4	NUM
iajs-1229	68	48	hours	hour	NOUN
iajs-1229	68	49	(	(	PUNCT
iajs-1229	68	50	the	the	DET
iajs-1229	68	51	maximum	maximum	ADJ
iajs-1229	68	52	concentration	concentration	NOUN
iajs-1229	68	53	of	of	ADP
iajs-1229	68	54	aspirin	aspirin	NOUN
iajs-1229	68	55	)	)	PUNCT
iajs-1229	68	56	.	.	PUNCT
iajs-1229	69	1	after	after	ADP
iajs-1229	69	2	4	4	NUM
iajs-1229	69	3	hour	hour	NOUN
iajs-1229	69	4	(	(	PUNCT
iajs-1229	69	5	6,8,10	6,8,10	NUM
iajs-1229	69	6	hr	hr	NOUN
iajs-1229	69	7	.	.	PUNCT
iajs-1229	69	8	)	)	PUNCT
iajs-1229	70	1	the	the	DET
iajs-1229	70	2	concentration	concentration	NOUN
iajs-1229	70	3	of	of	ADP
iajs-1229	70	4	aspirin	aspirin	NOUN
iajs-1229	70	5	was	be	AUX
iajs-1229	70	6	decreased	decrease	VERB
iajs-1229	70	7	.after	.after	ADJ
iajs-1229	70	8	10	10	NUM
iajs-1229	70	9	hours	hour	NOUN
iajs-1229	70	10	the	the	DET
iajs-1229	70	11	concentration	concentration	NOUN
iajs-1229	70	12	of	of	ADP
iajs-1229	70	13	aspirin	aspirin	NOUN
iajs-1229	70	14	was	be	AUX
iajs-1229	70	15	equal	equal	ADJ
iajs-1229	70	16	to	to	ADP
iajs-1229	70	17	the	the	DET
iajs-1229	70	18	aspirin	aspirin	NOUN
iajs-1229	70	19	concentration	concentration	NOUN
iajs-1229	70	20	in	in	ADP
iajs-1229	70	21	(	(	PUNCT
iajs-1229	70	22	2	2	NUM
iajs-1229	70	23	hours	hour	NOUN
iajs-1229	70	24	)	)	PUNCT
iajs-1229	70	25	.	.	PUNCT
iajs-1229	71	1	hydrolysis	hydrolysis	NOUN
iajs-1229	71	2	normally	normally	ADV
iajs-1229	71	3	accomplished	accomplish	VERB
iajs-1229	71	4	by	by	ADP
iajs-1229	71	5	esterase	esterase	NOUN
iajs-1229	71	6	enzyme	enzyme	NOUN
iajs-1229	71	7	present	present	ADJ
iajs-1229	71	8	in	in	ADP
iajs-1229	71	9	serum	serum	NOUN
iajs-1229	71	10	and	and	CCONJ
iajs-1229	71	11	other	other	ADJ
iajs-1229	71	12	tissues	tissue	NOUN
iajs-1229	71	13	capable	capable	ADJ
iajs-1229	71	14	or	or	CCONJ
iajs-1229	71	15	hydrolyzing	hydrolyze	VERB
iajs-1229	71	16	a	a	DET
iajs-1229	71	17	wide	wide	ADJ
iajs-1229	71	18	variety	variety	NOUN
iajs-1229	71	19	of	of	ADP
iajs-1229	71	20	ester	ester	NOUN
iajs-1229	71	21	linkages	linkage	NOUN
iajs-1229	71	22	like	like	ADP
iajs-1229	71	23	(	(	PUNCT
iajs-1229	71	24	ester	ester	NOUN
iajs-1229	71	25	hydrolase	hydrolase	NOUN
iajs-1229	71	26	,	,	PUNCT
iajs-1229	71	27	lipase	lipase	NOUN
iajs-1229	71	28	,	,	PUNCT
iajs-1229	71	29	cholesterol	cholesterol	NOUN
iajs-1229	71	30	esterase	esterase	NOUN
iajs-1229	71	31	,	,	PUNCT
iajs-1229	71	32	acetyl	acetyl	NOUN
iajs-1229	71	33	cholinesterase	cholinesterase	NOUN
iajs-1229	71	34	,	,	PUNCT
iajs-1229	71	35	carboxypeptidase	carboxypeptidase	NOUN
iajs-1229	71	36	)	)	PUNCT
iajs-1229	71	37	(	(	PUNCT
iajs-1229	71	38	15	15	NUM
iajs-1229	71	39	)	)	PUNCT
iajs-1229	71	40	.	.	PUNCT
iajs-1229	72	1	the	the	DET
iajs-1229	72	2	ester	ester	NOUN
iajs-1229	72	3	moiety	moiety	NOUN
iajs-1229	72	4	is	be	AUX
iajs-1229	72	5	subsequently	subsequently	ADV
iajs-1229	72	6	hydrolyzed	hydrolyze	VERB
iajs-1229	72	7	in	in	ADP
iajs-1229	72	8	the	the	DET
iajs-1229	72	9	gastrointestinal	gastrointestinal	ADJ
iajs-1229	72	10	tract	tract	NOUN
iajs-1229	72	11	and	and	CCONJ
iajs-1229	72	12	the	the	DET
iajs-1229	72	13	agent	agent	NOUN
iajs-1229	72	14	is	be	AUX
iajs-1229	72	15	absorbed	absorb	VERB
iajs-1229	72	16	as	as	ADP
iajs-1229	72	17	aspirin	aspirin	NOUN
iajs-1229	72	18	and	and	CCONJ
iajs-1229	72	19	vitamin	vitamin	NOUN
iajs-1229	72	20	c.	c.	PROPN
iajs-1229	72	21	schnabelruch	schnabelruch	PROPN
iajs-1229	72	22	and	and	CCONJ
iajs-1229	72	23	coworker(16	coworker(16	NOUN
iajs-1229	72	24	)	)	PUNCT
iajs-1229	72	25	(	(	PUNCT
iajs-1229	72	26	1990	1990	NUM
iajs-1229	72	27	)	)	PUNCT
iajs-1229	72	28	refer	refer	VERB
iajs-1229	72	29	to	to	ADP
iajs-1229	72	30	the	the	DET
iajs-1229	72	31	hydrolytic	hydrolytic	ADJ
iajs-1229	72	32	release	release	NOUN
iajs-1229	72	33	of	of	ADP
iajs-1229	72	34	the	the	DET
iajs-1229	72	35	bioactive	bioactive	ADJ
iajs-1229	72	36	agent	agent	NOUN
iajs-1229	72	37	(	(	PUNCT
iajs-1229	72	38	carboxymethyl	carboxymethyl	NOUN
iajs-1229	72	39	cellulose-2,2	cellulose-2,2	PROPN
iajs-1229	72	40	-	-	PUNCT
iajs-1229	72	41	dichloropropionates	dichloropropionate	NOUN
iajs-1229	72	42	)	)	PUNCT
iajs-1229	72	43	(	(	PUNCT
iajs-1229	72	44	cmc	cmc	NOUN
iajs-1229	72	45	ester	ester	NOUN
iajs-1229	72	46	)	)	PUNCT
iajs-1229	72	47	is	be	AUX
iajs-1229	72	48	mainly	mainly	ADV
iajs-1229	72	49	dependent	dependent	ADJ
iajs-1229	72	50	on	on	ADP
iajs-1229	72	51	the	the	DET
iajs-1229	72	52	hydrophilicity	hydrophilicity	NOUN
iajs-1229	72	53	of	of	ADP
iajs-1229	72	54	the	the	DET
iajs-1229	72	55	cmc	cmc	NOUN
iajs-1229	72	56	ester	ester	NOUN
iajs-1229	72	57	.	.	PUNCT
iajs-1229	73	1	in	in	ADP
iajs-1229	73	2	the	the	DET
iajs-1229	73	3	case	case	NOUN
iajs-1229	73	4	of	of	ADP
iajs-1229	73	5	containing	contain	VERB
iajs-1229	73	6	enzymatic	enzymatic	ADJ
iajs-1229	73	7	cleavable	cleavable	NOUN
iajs-1229	73	8	the	the	DET
iajs-1229	73	9	release	release	NOUN
iajs-1229	73	10	can	can	AUX
iajs-1229	73	11	be	be	AUX
iajs-1229	73	12	accelerated	accelerate	VERB
iajs-1229	73	13	by	by	ADP
iajs-1229	73	14	addition	addition	NOUN
iajs-1229	73	15	of	of	ADP
iajs-1229	73	16	esterase	esterase	NOUN
iajs-1229	73	17	.the	.the	X
iajs-1229	73	18	release	release	NOUN
iajs-1229	73	19	of	of	ADP
iajs-1229	73	20	2,2	2,2	ADJ
iajs-1229	73	21	-	-	ADJ
iajs-1229	73	22	dichloropropanic	dichloropropanic	ADJ
iajs-1229	73	23	acid	acid	NOUN
iajs-1229	73	24	from	from	ADP
iajs-1229	73	25	cmc	cmc	NOUN
iajs-1229	73	26	ester	ester	NOUN
iajs-1229	73	27	at	at	ADP
iajs-1229	73	28	30	30	NUM
iajs-1229	73	29	0	0	NUM
iajs-1229	73	30	c	c	NOUN
iajs-1229	73	31	and	and	CCONJ
iajs-1229	73	32	ph	ph	X
iajs-1229	73	33	7	7	NUM
iajs-1229	73	34	without	without	ADP
iajs-1229	73	35	addition	addition	NOUN
iajs-1229	73	36	of	of	ADP
iajs-1229	73	37	esterase	esterase	NOUN
iajs-1229	73	38	was	be	AUX
iajs-1229	73	39	8	8	NUM
iajs-1229	73	40	%	%	NOUN
iajs-1229	73	41	after	after	ADP
iajs-1229	73	42	100	100	NUM
iajs-1229	73	43	hours	hour	NOUN
iajs-1229	73	44	while	while	SCONJ
iajs-1229	73	45	the	the	DET
iajs-1229	73	46	release	release	NOUN
iajs-1229	73	47	of	of	ADP
iajs-1229	73	48	2,2	2,2	ADJ
iajs-1229	73	49	-	-	ADJ
iajs-1229	73	50	dichloropropanic	dichloropropanic	ADJ
iajs-1229	73	51	acid	acid	NOUN
iajs-1229	73	52	from	from	ADP
iajs-1229	73	53	cmc	cmc	NOUN
iajs-1229	73	54	ester	ester	NOUN
iajs-1229	73	55	at	at	ADP
iajs-1229	73	56	30	30	NUM
iajs-1229	73	57	0	0	NUM
iajs-1229	73	58	c	c	NOUN
iajs-1229	73	59	and	and	CCONJ
iajs-1229	73	60	ph	ph	X
iajs-1229	73	61	7	7	NUM
iajs-1229	73	62	with	with	ADP
iajs-1229	73	63	addition	addition	NOUN
iajs-1229	73	64	of	of	ADP
iajs-1229	73	65	esterase	esterase	NOUN
iajs-1229	73	66	was	be	AUX
iajs-1229	73	67	50	50	NUM
iajs-1229	73	68	%	%	NOUN
iajs-1229	73	69	after	after	ADP
iajs-1229	73	70	100	100	NUM
iajs-1229	73	71	hours	hour	NOUN
iajs-1229	73	72	.	.	PUNCT
iajs-1229	74	1	yi	yi	PROPN
iajs-1229	74	2	-	-	PUNCT
iajs-1229	74	3	nuo	nuo	PROPN
iajs-1229	74	4	pang	pang	NOUN
iajs-1229	74	5	et	et	PROPN
iajs-1229	74	6	al	al	PROPN
iajs-1229	74	7	(	(	PUNCT
iajs-1229	74	8	2002	2002	NUM
iajs-1229	74	9	)	)	PUNCT
iajs-1229	74	10	(	(	PUNCT
iajs-1229	74	11	17	17	NUM
iajs-1229	74	12	)	)	PUNCT
iajs-1229	74	13	refers	refer	VERB
iajs-1229	74	14	to	to	ADP
iajs-1229	74	15	that	that	PRON
iajs-1229	74	16	the	the	DET
iajs-1229	74	17	recovery	recovery	NOUN
iajs-1229	74	18	of	of	ADP
iajs-1229	74	19	dexamethasone	dexamethasone	NOUN
iajs-1229	74	20	(	(	PUNCT
iajs-1229	74	21	%	%	INTJ
iajs-1229	74	22	)	)	PUNCT
iajs-1229	74	23	in	in	ADP
iajs-1229	74	24	colon	colon	NOUN
iajs-1229	74	25	after	after	ADP
iajs-1229	74	26	(	(	PUNCT
iajs-1229	74	27	1,3,4,5,6,7,9	1,3,4,5,6,7,9	NUM
iajs-1229	74	28	)	)	PUNCT
iajs-1229	74	29	hours	hour	NOUN
iajs-1229	74	30	(	(	PUNCT
iajs-1229	74	31	oral	oral	ADJ
iajs-1229	74	32	administration	administration	NOUN
iajs-1229	74	33	)	)	PUNCT
iajs-1229	74	34	was	be	AUX
iajs-1229	74	35	(	(	PUNCT
iajs-1229	74	36	0,0,20.5,18.0,10.2,15.2,18.2)%	0,0,20.5,18.0,10.2,15.2,18.2)%	PRON
iajs-1229	74	37	respectively	respectively	ADV
iajs-1229	74	38	.	.	PUNCT
iajs-1229	75	1	these	these	DET
iajs-1229	75	2	results	result	NOUN
iajs-1229	75	3	showed	show	VERB
iajs-1229	75	4	that	that	SCONJ
iajs-1229	75	5	the	the	DET
iajs-1229	75	6	ester	ester	NOUN
iajs-1229	75	7	type	type	NOUN
iajs-1229	75	8	prodrugs	prodrug	NOUN
iajs-1229	75	9	of	of	ADP
iajs-1229	75	10	dexamethasone	dexamethasone	NOUN
iajs-1229	75	11	/	/	SYM
iajs-1229	75	12	dextran	dextran	NOUN
iajs-1229	75	13	(	(	PUNCT
iajs-1229	75	14	dsd	dsd	NOUN
iajs-1229	75	15	)	)	PUNCT
iajs-1229	75	16	release	release	VERB
iajs-1229	75	17	dexamethasone	dexamethasone	NOUN
iajs-1229	75	18	preferentially	preferentially	ADV
iajs-1229	75	19	on	on	ADP
iajs-1229	75	20	colonic	colonic	ADJ
iajs-1229	75	21	contents	content	NOUN
iajs-1229	75	22	after	after	ADP
iajs-1229	75	23	the	the	DET
iajs-1229	75	24	hydrolysis	hydrolysis	NOUN
iajs-1229	75	25	of	of	ADP
iajs-1229	75	26	dextran	dextran	NOUN
iajs-1229	75	27	to	to	PART
iajs-1229	75	28	small	small	ADJ
iajs-1229	75	29	oligosaccharides.the	oligosaccharides.the	DET
iajs-1229	75	30	dextran	dextran	ADJ
iajs-1229	75	31	conjugate	conjugate	NOUN
iajs-1229	75	32	survives	survive	VERB
iajs-1229	75	33	the	the	DET
iajs-1229	75	34	passage	passage	NOUN
iajs-1229	75	35	through	through	ADP
iajs-1229	75	36	upper	upper	ADJ
iajs-1229	75	37	gi	gi	NOUN
iajs-1229	75	38	tract	tract	NOUN
iajs-1229	75	39	although	although	SCONJ
iajs-1229	75	40	the	the	DET
iajs-1229	75	41	high	high	ADJ
iajs-1229	75	42	level	level	NOUN
iajs-1229	75	43	of	of	ADP
iajs-1229	75	44	esterase	esterase	NOUN
iajs-1229	75	45	in	in	ADP
iajs-1229	75	46	small	small	ADJ
iajs-1229	75	47	intestine	intestine	NOUN
iajs-1229	75	48	,	,	PUNCT
iajs-1229	75	49	indicating	indicate	VERB
iajs-1229	75	50	that	that	SCONJ
iajs-1229	75	51	dextran	dextran	NOUN
iajs-1229	75	52	protects	protect	VERB
iajs-1229	75	53	ester	ester	NOUN
iajs-1229	75	54	bond	bond	NOUN
iajs-1229	75	55	from	from	ADP
iajs-1229	75	56	hydrolysis	hydrolysis	NOUN
iajs-1229	75	57	by	by	ADP
iajs-1229	75	58	esterase	esterase	NOUN
iajs-1229	75	59	.	.	PUNCT
iajs-1229	76	1	this	this	DET
iajs-1229	76	2	result	result	NOUN
iajs-1229	76	3	,	,	PUNCT
iajs-1229	76	4	together	together	ADV
iajs-1229	76	5	with	with	ADP
iajs-1229	76	6	the	the	DET
iajs-1229	76	7	observation	observation	NOUN
iajs-1229	76	8	mentioned	mention	VERB
iajs-1229	76	9	above	above	ADV
iajs-1229	76	10	,	,	PUNCT
iajs-1229	76	11	suggests	suggest	VERB
iajs-1229	76	12	that	that	SCONJ
iajs-1229	76	13	bacterial	bacterial	ADJ
iajs-1229	76	14	enzymes	enzyme	NOUN
iajs-1229	76	15	in	in	ADP
iajs-1229	76	16	the	the	DET
iajs-1229	76	17	colon	colon	NOUN
iajs-1229	76	18	are	be	AUX
iajs-1229	76	19	responsible	responsible	ADJ
iajs-1229	76	20	for	for	ADP
iajs-1229	76	21	hydrolysis	hydrolysis	NOUN
iajs-1229	76	22	of	of	ADP
iajs-1229	76	23	dextran	dextran	ADJ
iajs-1229	76	24	conjugates	conjugate	NOUN
iajs-1229	76	25	.	.	PUNCT
iajs-1229	77	1	when	when	SCONJ
iajs-1229	77	2	dsd	dsd	PROPN
iajs-1229	77	3	reached	reach	VERB
iajs-1229	77	4	the	the	DET
iajs-1229	77	5	colon	colon	NOUN
iajs-1229	77	6	,	,	PUNCT
iajs-1229	77	7	dextran	dextran	PROPN
iajs-1229	77	8	was	be	AUX
iajs-1229	77	9	completely	completely	ADV
iajs-1229	77	10	hydrolyzed	hydrolyze	VERB
iajs-1229	77	11	into	into	ADP
iajs-1229	77	12	smaller	small	ADJ
iajs-1229	77	13	oligosaccharides	oligosaccharide	NOUN
iajs-1229	77	14	and	and	CCONJ
iajs-1229	77	15	exposed	expose	VERB
iajs-1229	77	16	the	the	DET
iajs-1229	77	17	ester	ester	NOUN
iajs-1229	77	18	bonds	bond	NOUN
iajs-1229	77	19	to	to	ADP
iajs-1229	77	20	esterase	esterase	NOUN
iajs-1229	77	21	,	,	PUNCT
iajs-1229	77	22	which	which	PRON
iajs-1229	77	23	led	lead	VERB
iajs-1229	77	24	to	to	ADP
iajs-1229	77	25	the	the	DET
iajs-1229	77	26	rapid	rapid	ADJ
iajs-1229	77	27	release	release	NOUN
iajs-1229	77	28	of	of	ADP
iajs-1229	77	29	dexamethasone	dexamethasone	NOUN
iajs-1229	77	30	.	.	PUNCT
iajs-1229	78	1	the	the	DET
iajs-1229	78	2	bacterial	bacterial	ADJ
iajs-1229	78	3	count	count	NOUN
iajs-1229	78	4	in	in	ADP
iajs-1229	78	5	the	the	DET
iajs-1229	78	6	colon	colon	NOUN
iajs-1229	78	7	is	be	AUX
iajs-1229	78	8	much	much	ADV
iajs-1229	78	9	higher	high	ADJ
iajs-1229	78	10	than	than	ADP
iajs-1229	78	11	that	that	PRON
iajs-1229	78	12	in	in	ADP
iajs-1229	78	13	upper	upper	ADJ
iajs-1229	78	14	gi	gi	NOUN
iajs-1229	78	15	tract(18	tract(18	NOUN
iajs-1229	78	16	)	)	PUNCT
iajs-1229	78	17	.	.	PUNCT
iajs-1229	79	1	the	the	DET
iajs-1229	79	2	colonic	colonic	PROPN
iajs-1229	79	3	micro	micro	ADJ
iajs-1229	79	4	flora	flora	NOUN
iajs-1229	79	5	produces	produce	VERB
iajs-1229	79	6	a	a	DET
iajs-1229	79	7	variety	variety	NOUN
iajs-1229	79	8	of	of	ADP
iajs-1229	79	9	enzymes	enzyme	NOUN
iajs-1229	79	10	,	,	PUNCT
iajs-1229	79	11	including	include	VERB
iajs-1229	79	12	azoreductase	azoreductase	NOUN
iajs-1229	79	13	,	,	PUNCT
iajs-1229	79	14	various	various	ADJ
iajs-1229	79	15	glycosidases	glycosidase	NOUN
iajs-1229	79	16	and	and	CCONJ
iajs-1229	79	17	amidases	amidase	NOUN
iajs-1229	79	18	,	,	PUNCT
iajs-1229	79	19	which	which	PRON
iajs-1229	79	20	are	be	AUX
iajs-1229	79	21	not	not	PART
iajs-1229	79	22	present	present	ADJ
iajs-1229	79	23	in	in	ADP
iajs-1229	79	24	the	the	DET
iajs-1229	79	25	stomach	stomach	NOUN
iajs-1229	79	26	or	or	CCONJ
iajs-1229	79	27	the	the	DET
iajs-1229	79	28	small	small	ADJ
iajs-1229	79	29	intestine	intestine	NOUN
iajs-1229	79	30	.	.	PUNCT
iajs-1229	80	1	therefore	therefore	ADV
iajs-1229	80	2	,	,	PUNCT
iajs-1229	80	3	enzyme	enzyme	VERB
iajs-1229	80	4	dependent	dependent	ADJ
iajs-1229	80	5	drug	drug	NOUN
iajs-1229	80	6	release	release	NOUN
iajs-1229	80	7	,	,	PUNCT
iajs-1229	80	8	which	which	PRON
iajs-1229	80	9	relies	rely	VERB
iajs-1229	80	10	on	on	ADP
iajs-1229	80	11	the	the	DET
iajs-1229	80	12	existence	existence	NOUN
iajs-1229	80	13	of	of	ADP
iajs-1229	80	14	enzyme	enzyme	NOUN
iajs-1229	80	15	drug	drug	NOUN
iajs-1229	80	16	—	—	PUNCT
iajs-1229	80	17	c	c	X
iajs-1229	80	18	—	—	PUNCT
iajs-1229	80	19	oh	oh	INTJ
iajs-1229	80	20	+	+	NUM
iajs-1229	80	21	ho	ho	ADJ
iajs-1229	80	22	--	--	PUNCT
iajs-1229	80	23	promoiety	promoiety	NOUN
iajs-1229	80	24	or	or	CCONJ
iajs-1229	80	25	drug	drug	NOUN
iajs-1229	80	26	—	—	PUNCT
iajs-1229	80	27	oh	oh	INTJ
iajs-1229	80	28	+	+	ADJ
iajs-1229	80	29	ho	ho	ADJ
iajs-1229	80	30	--	--	PUNCT
iajs-1229	80	31	c	c	X
iajs-1229	80	32	--	--	PUNCT
iajs-1229	80	33	promoiety	promoiety	NOUN
iajs-1229	80	34	esterase	esterase	NOUN
iajs-1229	80	35	drug	drug	NOUN
iajs-1229	80	36	—	—	PUNCT
iajs-1229	80	37	c	c	X
iajs-1229	80	38	—	—	PUNCT
iajs-1229	80	39	o	o	NOUN
iajs-1229	80	40	—	—	PUNCT
iajs-1229	80	41	promoiety	promoiety	NOUN
iajs-1229	80	42	or	or	CCONJ
iajs-1229	80	43	drug	drug	NOUN
iajs-1229	80	44	—	—	PUNCT
iajs-1229	80	45	o	o	NOUN
iajs-1229	80	46	—	—	PUNCT
iajs-1229	80	47	c	c	X
iajs-1229	80	48	--	--	PUNCT
iajs-1229	80	49	promoiety	promoiety	NOUN
iajs-1229	81	1	o	o	NOUN
iajs-1229	82	1	o	o	X
iajs-1229	82	2	o	o	X
iajs-1229	82	3	o	o	X
iajs-1229	82	4	ibn	ibn	PROPN
iajs-1229	82	5	alhaitham	alhaitham	NOUN
iajs-1229	82	6	j.	j.	PROPN
iajs-1229	82	7	for	for	ADP
iajs-1229	82	8	pure	pure	ADJ
iajs-1229	82	9	&	&	CCONJ
iajs-1229	82	10	appl	appl	PROPN
iajs-1229	82	11	.	.	PUNCT
iajs-1229	83	1	sci	sci	PROPN
iajs-1229	83	2	vol.22	vol.22	PROPN
iajs-1229	83	3	(	(	PUNCT
iajs-1229	83	4	2	2	NUM
iajs-1229	83	5	)	)	PUNCT
iajs-1229	83	6	2009	2009	NUM
iajs-1229	83	7	producing	produce	VERB
iajs-1229	83	8	microorganisms	microorganism	NOUN
iajs-1229	83	9	in	in	ADP
iajs-1229	83	10	the	the	DET
iajs-1229	83	11	colon	colon	NOUN
iajs-1229	83	12	,	,	PUNCT
iajs-1229	83	13	could	could	AUX
iajs-1229	83	14	be	be	AUX
iajs-1229	83	15	used	use	VERB
iajs-1229	83	16	to	to	PART
iajs-1229	83	17	deliver	deliver	VERB
iajs-1229	83	18	drug	drug	NOUN
iajs-1229	83	19	to	to	ADP
iajs-1229	83	20	the	the	DET
iajs-1229	83	21	colon	colon	NOUN
iajs-1229	83	22	after	after	ADP
iajs-1229	83	23	enzymatic	enzymatic	ADJ
iajs-1229	83	24	cleavage	cleavage	NOUN
iajs-1229	83	25	of	of	ADP
iajs-1229	83	26	degradable	degradable	ADJ
iajs-1229	83	27	carrier	carrier	NOUN
iajs-1229	83	28	bonds	bond	NOUN
iajs-1229	83	29	.	.	PUNCT
iajs-1229	84	1	references	reference	NOUN
iajs-1229	84	2	1	1	NUM
iajs-1229	84	3	.	.	PUNCT
iajs-1229	84	4	houston	houston	PROPN
iajs-1229	84	5	,	,	PUNCT
iajs-1229	84	6	jb.llevy	jb.llevy	NOUN
iajs-1229	84	7	,	,	PUNCT
iajs-1229	84	8	g	g	NOUN
iajs-1229	84	9	,	,	PUNCT
iajs-1229	84	10	j.pharm	j.pharm	PROPN
iajs-1229	84	11	.	.	PUNCT
iajs-1229	85	1	,65(1976)1218	,65(1976)1218	PROPN
iajs-1229	85	2	.	.	PUNCT
iajs-1229	86	1	2	2	X
iajs-1229	86	2	.	.	X
iajs-1229	86	3	mitra	mitra	PROPN
iajs-1229	86	4	a.	a.	PROPN
iajs-1229	86	5	,et	,et	PROPN
iajs-1229	86	6	al	al	PROPN
iajs-1229	86	7	.	.	PROPN
iajs-1229	86	8	,biochem.toxicol	,biochem.toxicol	PROPN
iajs-1229	86	9	.	.	PUNCT
iajs-1229	86	10	,summer,6(2)(1991)93	,summer,6(2)(1991)93	PUNCT
iajs-1229	86	11	.	.	PUNCT
iajs-1229	87	1	3	3	X
iajs-1229	87	2	.	.	X
iajs-1229	87	3	mitra	mitra	PROPN
iajs-1229	87	4	a.	a.	PROPN
iajs-1229	87	5	,et	,et	PROPN
iajs-1229	87	6	al	al	PROPN
iajs-1229	87	7	.	.	PROPN
iajs-1229	87	8	,toxicol.litt	,toxicol.litt	PROPN
iajs-1229	87	9	.	.	PUNCT
iajs-1229	88	1	,nov	,nov	PUNCT
iajs-1229	88	2	.	.	PUNCT
iajs-1229	89	1	,44(1	,44(1	X
iajs-1229	89	2	-	-	PUNCT
iajs-1229	89	3	2)(1988)39	2)(1988)39	NOUN
iajs-1229	89	4	.	.	PUNCT
iajs-1229	90	1	4.coffey	4.coffey	NUM
iajs-1229	90	2	g.	g.	NOUN
iajs-1229	90	3	,wilson	,wilson	PUNCT
iajs-1229	90	4	cwm.br	cwm.br	PROPN
iajs-1229	90	5	.med.j	.med.j	PUNCT
iajs-1229	90	6	.	.	PUNCT
iajs-1229	90	7	,jan	,jan	PROPN
iajs-1229	90	8	.	.	PUNCT
iajs-1229	91	1	25,1	25,1	NOUN
iajs-1229	91	2	(	(	PUNCT
iajs-1229	91	3	5951	5951	NUM
iajs-1229	91	4	)	)	PUNCT
iajs-1229	91	5	(	(	PUNCT
iajs-1229	91	6	1975	1975	NUM
iajs-1229	91	7	)	)	PUNCT
iajs-1229	91	8	208	208	NUM
iajs-1229	91	9	.	.	X
iajs-1229	92	1	5	5	X
iajs-1229	92	2	.	.	X
iajs-1229	92	3	daniels	daniels	PROPN
iajs-1229	92	4	a.	a.	PROPN
iajs-1229	92	5	,everson	,everson	PUNCT
iajs-1229	92	6	gj	gj	PROPN
iajs-1229	92	7	.	.	PROPN
iajs-1229	92	8	,	,	PUNCT
iajs-1229	92	9	proc.soc	proc.soc	PROPN
iajs-1229	92	10	.	.	PROPN
iajs-1229	92	11	,exp.biol.med	,exp.biol.med	PROPN
iajs-1229	92	12	.	.	PUNCT
iajs-1229	92	13	,	,	PUNCT
iajs-1229	92	14	35(1936	35(1936	NUM
iajs-1229	92	15	-	-	SYM
iajs-1229	92	16	1937)20	1937)20	NUM
iajs-1229	92	17	-	-	PUNCT
iajs-1229	92	18	24	24	NUM
iajs-1229	92	19	.	.	PUNCT
iajs-1229	92	20	6	6	NUM
iajs-1229	92	21	.	.	X
iajs-1229	92	22	buist	buist	NOUN
iajs-1229	92	23	r	r	NOUN
iajs-1229	92	24	a.	a.	NOUN
iajs-1229	92	25	,	,	PUNCT
iajs-1229	92	26	int	int	NOUN
iajs-1229	92	27	.	.	PUNCT
iajs-1229	93	1	clin	clin	PROPN
iajs-1229	93	2	.	.	PUNCT
iajs-1229	94	1	nutr	nutr	PROPN
iajs-1229	94	2	.	.	PROPN
iajs-1229	94	3	rev	rev	PROPN
iajs-1229	94	4	.	.	PROPN
iajs-1229	94	5	,	,	PUNCT
iajs-1229	94	6	4(3)(1984)114	4(3)(1984)114	NUM
iajs-1229	94	7	.	.	PUNCT
iajs-1229	95	1	(	(	PUNCT
iajs-1229	95	2	166	166	NUM
iajs-1229	95	3	)	)	PUNCT
iajs-1229	95	4	ascorbic	ascorbic	NOUN
iajs-1229	95	5	acid	acid	NOUN
iajs-1229	95	6	/	/	SYM
iajs-1229	95	7	vitamin	vitamin	NOUN
iajs-1229	95	8	c	c	NOUN
iajs-1229	95	9	technology	technology	NOUN
iajs-1229	95	10	enco	enco	PROPN
iajs-1229	95	11	engineering	engineering	PROPN
iajs-1229	95	12	chur	chur	PROPN
iajs-1229	95	13	ag	ag	PROPN
iajs-1229	95	14	switzerland	switzerland	PROPN
iajs-1229	95	15	enco@spin.ch	enco@spin.ch	PROPN
iajs-1229	95	16	7	7	NUM
iajs-1229	95	17	.	.	PUNCT
iajs-1229	95	18	e.l.hirst	e.l.hirst	PROPN
iajs-1229	95	19	,	,	PUNCT
iajs-1229	95	20	j.chem.soc	j.chem.soc	PROPN
iajs-1229	95	21	.	.	PROPN
iajs-1229	95	22	,	,	PUNCT
iajs-1229	95	23	1nd	1nd	PROPN
iajs-1229	95	24	.	.	PUNCT
iajs-1229	95	25	,	,	PUNCT
iajs-1229	96	1	52(1933)221,ibid	52(1933)221,ibid	NOUN
iajs-1229	96	2	482	482	NUM
iajs-1229	96	3	.	.	NOUN
iajs-1229	96	4	8	8	NUM
iajs-1229	96	5	.	.	NOUN
iajs-1229	96	6	e.micheel	e.micheel	NOUN
iajs-1229	96	7	and	and	CCONJ
iajs-1229	96	8	k.kraft	k.kraft	PROPN
iajs-1229	96	9	,	,	PUNCT
iajs-1229	96	10	hoppe	hoppe	PROPN
iajs-1229	96	11	-	-	PUNCT
iajs-1229	96	12	seyler	seyler	NOUN
iajs-1229	96	13	s	s	PART
iajs-1229	96	14	z.physiol	z.physiol	ADJ
iajs-1229	96	15	.	.	PUNCT
iajs-1229	97	1	chem	chem	PROPN
iajs-1229	97	2	.	.	PUNCT
iajs-1229	97	3	,	,	PUNCT
iajs-1229	97	4	222(1933)235	222(1933)235	X
iajs-1229	97	5	.	.	NOUN
iajs-1229	97	6	9	9	NUM
iajs-1229	97	7	.	.	X
iajs-1229	98	1	j.c.krantz	j.c.krantz	PROPN
iajs-1229	98	2	,	,	PUNCT
iajs-1229	98	3	jr	jr	PROPN
iajs-1229	98	4	and	and	CCONJ
iajs-1229	98	5	c.j.carr	c.j.carr	NOUN
iajs-1229	98	6	,	,	PUNCT
iajs-1229	98	7	“	"	PUNCT
iajs-1229	98	8	the	the	DET
iajs-1229	98	9	pharmacologic	pharmacologic	ADJ
iajs-1229	98	10	principles	principle	NOUN
iajs-1229	98	11	of	of	ADP
iajs-1229	98	12	medical	medical	ADJ
iajs-1229	98	13	practice	practice	NOUN
iajs-1229	98	14	”	"	PUNCT
iajs-1229	98	15	,	,	PUNCT
iajs-1229	98	16	ed	ed	NOUN
iajs-1229	98	17	.	.	PROPN
iajs-1229	98	18	,	,	PUNCT
iajs-1229	98	19	the	the	DET
iajs-1229	98	20	williams	williams	PROPN
iajs-1229	98	21	and	and	CCONJ
iajs-1229	98	22	wilkins	wilkins	PROPN
iajs-1229	98	23	company	company	PROPN
iajs-1229	98	24	,	,	PUNCT
iajs-1229	98	25	usa	usa	PROPN
iajs-1229	98	26	,	,	PUNCT
iajs-1229	98	27	4	4	NUM
iajs-1229	98	28	th	th	NUM
iajs-1229	98	29	ed.(1958	ed.(1958	NOUN
iajs-1229	98	30	)	)	PUNCT
iajs-1229	98	31	.	.	PUNCT
iajs-1229	99	1	10	10	NUM
iajs-1229	99	2	.	.	X
iajs-1229	100	1	l.pauling	l.paule	VERB
iajs-1229	100	2	,	,	PUNCT
iajs-1229	100	3	"	"	PUNCT
iajs-1229	100	4	vitamin	vitamin	VERB
iajs-1229	100	5	c.the	c.the	DET
iajs-1229	100	6	common	common	ADJ
iajs-1229	100	7	cold	cold	NOUN
iajs-1229	100	8	and	and	CCONJ
iajs-1229	100	9	the	the	DET
iajs-1229	100	10	flu",ed	flu",ed	NOUN
iajs-1229	100	11	.	.	PROPN
iajs-1229	100	12	,	,	PUNCT
iajs-1229	100	13	w.h.free	w.h.free	ADJ
iajs-1229	100	14	man	man	NOUN
iajs-1229	100	15	and	and	CCONJ
iajs-1229	100	16	company	company	NOUN
iajs-1229	100	17	,	,	PUNCT
iajs-1229	100	18	san	san	PROPN
iajs-1229	100	19	francisco	francisco	PROPN
iajs-1229	100	20	,	,	PUNCT
iajs-1229	100	21	(	(	PUNCT
iajs-1229	100	22	1972)pp.33	1972)pp.33	NUM
iajs-1229	100	23	-	-	SYM
iajs-1229	100	24	46	46	NUM
iajs-1229	100	25	.	.	PUNCT
iajs-1229	101	1	11	11	NUM
iajs-1229	101	2	.	.	PUNCT
iajs-1229	101	3	l.	l.	PROPN
iajs-1229	101	4	l.	l.	PROPN
iajs-1229	101	5	salomon	salomon	PROPN
iajs-1229	101	6	,	,	PUNCT
iajs-1229	101	7	experientia	experientia	PROPN
iajs-1229	101	8	,	,	PUNCT
iajs-1229	101	9	19(12)(1963)6119	19(12)(1963)6119	NUM
iajs-1229	101	10	12	12	NUM
iajs-1229	101	11	.	.	PUNCT
iajs-1229	102	1	n.nomura	n.nomura	ADJ
iajs-1229	102	2	and	and	CCONJ
iajs-1229	102	3	k.	k.	PROPN
iajs-1229	102	4	sugimoto	sugimoto	PROPN
iajs-1229	102	5	,	,	PUNCT
iajs-1229	102	6	chem	chem	NOUN
iajs-1229	102	7	.	.	PUNCT
iajs-1229	103	1	parm	parm	PROPN
iajs-1229	103	2	.	.	PUNCT
iajs-1229	104	1	bull	bull	PROPN
iajs-1229	104	2	.	.	PUNCT
iajs-1229	105	1	,	,	PUNCT
iajs-1229	105	2	14(9	14(9	NUM
iajs-1229	105	3	)	)	PUNCT
iajs-1229	105	4	(	(	PUNCT
iajs-1229	105	5	1966	1966	NUM
iajs-1229	105	6	)	)	PUNCT
iajs-1229	105	7	1039	1039	NUM
iajs-1229	105	8	.	.	PUNCT
iajs-1229	106	1	,	,	PUNCT
iajs-1229	106	2	,	,	PUNCT
iajs-1229	106	3	.nomura	.nomura	PUNCT
iajs-1229	106	4	and	and	CCONJ
iajs-1229	106	5	k.	k.	PROPN
iajs-1229	106	6	sugimoto	sugimoto	PROPN
iajs-1229	106	7	,	,	PUNCT
iajs-1229	106	8	takeda	takeda	PROPN
iajs-1229	106	9	chemical	chemical	NOUN
iajs-1229	106	10	industries	industry	NOUN
iajs-1229	106	11	,	,	PUNCT
iajs-1229	106	12	ltd	ltd	PROPN
iajs-1229	106	13	.	.	PROPN
iajs-1229	106	14	,	,	PUNCT
iajs-1229	106	15	6809	6809	NUM
iajs-1229	106	16	,	,	PUNCT
iajs-1229	106	17	550(c1.16.e38	550(c1.16.e38	NUM
iajs-1229	106	18	)	)	PUNCT
iajs-1229	106	19	,	,	PUNCT
iajs-1229	106	20	(	(	PUNCT
iajs-1229	106	21	1968	1968	NUM
iajs-1229	106	22	)	)	PUNCT
iajs-1229	106	23	,	,	PUNCT
iajs-1229	106	24	japan	japan	PROPN
iajs-1229	106	25	,	,	PUNCT
iajs-1229	106	26	appl	appl	PROPN
iajs-1229	106	27	.	.	PROPN
iajs-1229	106	28	,	,	PUNCT
iajs-1229	106	29	(	(	PUNCT
iajs-1229	106	30	1965)2pp	1965)2pp	NUM
iajs-1229	106	31	14	14	NUM
iajs-1229	106	32	.	.	PUNCT
iajs-1229	107	1	rudolph	rudolph	PROPN
iajs-1229	107	2	mw	mw	PROPN
iajs-1229	107	3	,	,	PUNCT
iajs-1229	107	4	klein	klein	PROPN
iajs-1229	107	5	s	s	PROPN
iajs-1229	107	6	,	,	PUNCT
iajs-1229	107	7	beckert	beckert	PROPN
iajs-1229	107	8	te	te	PROPN
iajs-1229	107	9	,	,	PUNCT
iajs-1229	107	10	petereit	petereit	PROPN
iajs-1229	107	11	hu	hu	PROPN
iajs-1229	107	12	,	,	PUNCT
iajs-1229	107	13	dressman	dressman	PROPN
iajs-1229	107	14	jb	jb	PROPN
iajs-1229	107	15	.	.	PUNCT
iajs-1229	108	1	"	"	PUNCT
iajs-1229	108	2	a	a	DET
iajs-1229	108	3	new	new	ADJ
iajs-1229	108	4	5	5	NUM
iajs-1229	108	5	-	-	PUNCT
iajs-1229	108	6	aminosalicylic	aminosalicylic	NOUN
iajs-1229	108	7	acid	acid	PROPN
iajs-1229	108	8	multi	multi	ADJ
iajs-1229	108	9	-	-	ADJ
iajs-1229	108	10	unit	unit	ADJ
iajs-1229	108	11	dasage	dasage	NOUN
iajs-1229	108	12	form	form	NOUN
iajs-1229	108	13	for	for	ADP
iajs-1229	108	14	the	the	DET
iajs-1229	108	15	therapy	therapy	NOUN
iajs-1229	108	16	of	of	ADP
iajs-1229	108	17	ulcerative	ulcerative	ADJ
iajs-1229	108	18	colitis	colitis	NOUN
iajs-1229	108	19	"	"	PUNCT
iajs-1229	108	20	.	.	PUNCT
iajs-1229	109	1	eur	eur	PROPN
iajs-1229	109	2	j	j	PROPN
iajs-1229	109	3	pharm	pharm	PROPN
iajs-1229	109	4	biopharm	biopharm	PROPN
iajs-1229	109	5	2001	2001	NUM
iajs-1229	109	6	;	;	PUNCT
iajs-1229	109	7	51	51	NUM
iajs-1229	109	8	:	:	SYM
iajs-1229	109	9	183	183	NUM
iajs-1229	109	10	-	-	SYM
iajs-1229	109	11	190	190	NUM
iajs-1229	109	12	15	15	NUM
iajs-1229	109	13	.	.	PUNCT
iajs-1229	110	1	wilson	wilson	PROPN
iajs-1229	110	2	and	and	CCONJ
iajs-1229	110	3	gisvold	gisvold	VERB
iajs-1229	110	4	"	"	PUNCT
iajs-1229	110	5	drug	drug	NOUN
iajs-1229	110	6	latentiation	latentiation	NOUN
iajs-1229	110	7	and	and	CCONJ
iajs-1229	110	8	prodrugs	prodrug	NOUN
iajs-1229	110	9	"	"	PUNCT
iajs-1229	110	10	1998,p123	1998,p123	NUM
iajs-1229	110	11	-	-	SYM
iajs-1229	110	12	137	137	NUM
iajs-1229	110	13	16	16	NUM
iajs-1229	110	14	.	.	PUNCT
iajs-1229	111	1	matthias	matthias	PROPN
iajs-1229	111	2	schnabelruch	schnabelruch	PROPN
iajs-1229	111	3	,	,	PUNCT
iajs-1229	111	4	gunter	gunter	NOUN
iajs-1229	111	5	geschwend	geschwend	PROPN
iajs-1229	111	6	,	,	PUNCT
iajs-1229	111	7	and	and	CCONJ
iajs-1229	111	8	dieter	dieter	NOUN
iajs-1229	111	9	klemm	klemm	NOUN
iajs-1229	111	10	(	(	PUNCT
iajs-1229	111	11	1990)"synthesis	1990)"synthesis	NUM
iajs-1229	111	12	of	of	ADP
iajs-1229	111	13	bioactive	bioactive	ADJ
iajs-1229	111	14	2,2dichloropropionic	2,2dichloropropionic	NUM
iajs-1229	111	15	acid	acid	NOUN
iajs-1229	111	16	esters	ester	NOUN
iajs-1229	111	17	of	of	ADP
iajs-1229	111	18	carboxymethyl	carboxymethyl	NOUN
iajs-1229	111	19	cellulose	cellulose	NOUN
iajs-1229	111	20	and	and	CCONJ
iajs-1229	111	21	investigations	investigation	NOUN
iajs-1229	111	22	on	on	ADP
iajs-1229	111	23	their	their	PRON
iajs-1229	111	24	release	release	NOUN
iajs-1229	111	25	behavior"journal	behavior"journal	NOUN
iajs-1229	111	26	of	of	ADP
iajs-1229	111	27	applied	apply	VERB
iajs-1229	111	28	polymer	polymer	NOUN
iajs-1229	111	29	science,39	science,39	NOUN
iajs-1229	111	30	:	:	PUNCT
iajs-1229	111	31	621	621	NUM
iajs-1229	111	32	-	-	SYM
iajs-1229	111	33	628	628	NUM
iajs-1229	111	34	17	17	NUM
iajs-1229	111	35	.	.	PUNCT
iajs-1229	112	1	yi	yi	PROPN
iajs-1229	112	2	-	-	PUNCT
iajs-1229	112	3	nuo	nuo	PROPN
iajs-1229	112	4	pang	pang	NOUN
iajs-1229	112	5	,	,	PUNCT
iajs-1229	112	6	yan	yan	PROPN
iajs-1229	112	7	zhang	zhang	PROPN
iajs-1229	112	8	,	,	PUNCT
iajs-1229	112	9	zhi	zhi	PROPN
iajs-1229	112	10	-	-	PUNCT
iajs-1229	112	11	rong	rong	PROPN
iajs-1229	112	12	zhang	zhang	PROPN
iajs-1229	113	1	"	"	PUNCT
iajs-1229	113	2	synthesis	synthesis	NOUN
iajs-1229	113	3	of	of	ADP
iajs-1229	113	4	an	an	DET
iajs-1229	113	5	enzyme	enzyme	NOUN
iajs-1229	113	6	-	-	PUNCT
iajs-1229	113	7	dependent	dependent	ADJ
iajs-1229	113	8	prodrug	prodrug	NOUN
iajs-1229	113	9	and	and	CCONJ
iajs-1229	113	10	evaluation	evaluation	NOUN
iajs-1229	113	11	of	of	ADP
iajs-1229	113	12	its	its	PRON
iajs-1229	113	13	potential	potential	NOUN
iajs-1229	113	14	for	for	ADP
iajs-1229	113	15	colon	colon	NOUN
iajs-1229	113	16	targeting	target	VERB
iajs-1229	113	17	"	"	PUNCT
iajs-1229	113	18	world	world	NOUN
iajs-1229	113	19	gastroenterl	gastroenterl	NOUN
iajs-1229	113	20	2002	2002	NUM
iajs-1229	113	21	october	october	PROPN
iajs-1229	113	22	15,8(5):913	15,8(5):913	NUM
iajs-1229	113	23	-	-	SYM
iajs-1229	113	24	917	917	NUM
iajs-1229	113	25	18	18	NUM
iajs-1229	113	26	.	.	PUNCT
iajs-1229	114	1	mcleod	mcleod	PROPN
iajs-1229	114	2	ad	ad	PROPN
iajs-1229	114	3	,	,	PUNCT
iajs-1229	114	4	friend	friend	NOUN
iajs-1229	114	5	dr	dr	PROPN
iajs-1229	114	6	,	,	PUNCT
iajs-1229	114	7	tozer	tozer	PROPN
iajs-1229	114	8	tn	tn	PROPN
iajs-1229	114	9	.	.	PUNCT
iajs-1229	115	1	glucocorticoid	glucocorticoid	ADJ
iajs-1229	115	2	-	-	PUNCT
iajs-1229	115	3	dextran	dextran	NOUN
iajs-1229	115	4	conjugates	conjugate	NOUN
iajs-1229	115	5	as	as	ADP
iajs-1229	115	6	potential	potential	ADJ
iajs-1229	115	7	prodrugs	prodrug	NOUN
iajs-1229	115	8	for	for	ADP
iajs-1229	115	9	colon	colon	NOUN
iajs-1229	115	10	-	-	PUNCT
iajs-1229	115	11	specific	specific	ADJ
iajs-1229	115	12	delivery	delivery	NOUN
iajs-1229	115	13	:	:	PUNCT
iajs-1229	115	14	hydrolysis	hydrolysis	NOUN
iajs-1229	115	15	in	in	ADP
iajs-1229	115	16	rat	rat	NOUN
iajs-1229	115	17	gastrointestinal	gastrointestinal	ADJ
iajs-1229	115	18	tract	tract	NOUN
iajs-1229	115	19	contents	content	NOUN
iajs-1229	115	20	.	.	PUNCT
iajs-1229	116	1	j	j	PROPN
iajs-1229	116	2	pharmsci(1994	pharmsci(1994	NOUN
iajs-1229	116	3	)	)	PUNCT
iajs-1229	117	1	83:1284	83:1284	ADV
iajs-1229	117	2	-	-	SYM
iajs-1229	117	3	1288	1288	NUM
iajs-1229	117	4	table	table	NOUN
iajs-1229	117	5	(	(	PUNCT
iajs-1229	117	6	1	1	NUM
iajs-1229	117	7	)	)	PUNCT
iajs-1229	117	8	concentration	concentration	NOUN
iajs-1229	117	9	of	of	ADP
iajs-1229	117	10	aspirin	aspirin	NOUN
iajs-1229	117	11	in	in	ADP
iajs-1229	117	12	rabbit	rabbit	NOUN
iajs-1229	117	13	blood	blood	NOUN
iajs-1229	117	14	serum	serum	NOUN
iajs-1229	118	1	[	[	X
iajs-1229	118	2	compound	compound	NOUN
iajs-1229	118	3	(	(	PUNCT
iajs-1229	118	4	1	1	NUM
iajs-1229	118	5	)	)	PUNCT
iajs-1229	118	6	]	]	PUNCT
iajs-1229	118	7	time	time	NOUN
iajs-1229	118	8	(	(	PUNCT
iajs-1229	118	9	hr	hr	NOUN
iajs-1229	118	10	)	)	PUNCT
iajs-1229	118	11	concentration	concentration	NOUN
iajs-1229	118	12	m	m	NOUN
iajs-1229	118	13	0	0	NUM
iajs-1229	118	14	0	0	NUM
iajs-1229	118	15	2	2	NUM
iajs-1229	118	16	3.71x10	3.71x10	NUM
iajs-1229	118	17	-5	-5	NOUN
iajs-1229	118	18	3	3	NUM
iajs-1229	118	19	3.2x10	3.2x10	NUM
iajs-1229	118	20	-3	-3	SYM
iajs-1229	118	21	4	4	NUM
iajs-1229	118	22	4.08x10	4.08x10	NUM
iajs-1229	118	23	-3	-3	SYM
iajs-1229	118	24	6	6	NUM
iajs-1229	118	25	3.41x10	3.41x10	NUM
iajs-1229	118	26	-3	-3	SYM
iajs-1229	118	27	8	8	NUM
iajs-1229	118	28	4.61x10	4.61x10	NUM
iajs-1229	118	29	-4	-4	NUM
iajs-1229	118	30	10	10	NUM
iajs-1229	118	31	3.601x10	3.601x10	NUM
iajs-1229	118	32	-5	-5	NOUN
iajs-1229	118	33	mailto:enco@spin.ch	mailto:enco@spin.ch	PROPN
iajs-1229	118	34	ibn	ibn	PROPN
iajs-1229	118	35	alhaitham	alhaitham	PROPN
iajs-1229	118	36	j.	j.	PROPN
iajs-1229	118	37	for	for	ADP
iajs-1229	118	38	pure	pure	ADJ
iajs-1229	118	39	&	&	CCONJ
iajs-1229	118	40	appl	appl	PROPN
iajs-1229	118	41	.	.	PUNCT
iajs-1229	119	1	sci	sci	PROPN
iajs-1229	119	2	vol.22	vol.22	PROPN
iajs-1229	119	3	(	(	PUNCT
iajs-1229	119	4	2	2	NUM
iajs-1229	119	5	)	)	PUNCT
iajs-1229	119	6	2009	2009	NUM
iajs-1229	119	7	table	table	NOUN
iajs-1229	119	8	(	(	PUNCT
iajs-1229	119	9	2	2	NUM
iajs-1229	119	10	)	)	PUNCT
iajs-1229	119	11	concentration	concentration	NOUN
iajs-1229	119	12	of	of	ADP
iajs-1229	119	13	aspirin	aspirin	NOUN
iajs-1229	119	14	in	in	ADP
iajs-1229	119	15	rabbit	rabbit	NOUN
iajs-1229	119	16	blood	blood	NOUN
iajs-1229	119	17	serum	serum	NOUN
iajs-1229	120	1	[	[	X
iajs-1229	120	2	compound	compound	NOUN
iajs-1229	120	3	(	(	PUNCT
iajs-1229	120	4	2	2	NUM
iajs-1229	120	5	)	)	PUNCT
iajs-1229	120	6	]	]	PUNCT
iajs-1229	120	7	time	time	NOUN
iajs-1229	120	8	(	(	PUNCT
iajs-1229	120	9	hr	hr	NOUN
iajs-1229	120	10	)	)	PUNCT
iajs-1229	120	11	concentration	concentration	NOUN
iajs-1229	120	12	m	m	NOUN
iajs-1229	120	13	0	0	NUM
iajs-1229	120	14	0	0	NUM
iajs-1229	120	15	2	2	NUM
iajs-1229	120	16	7.52x10	7.52x10	NUM
iajs-1229	120	17	-5	-5	NOUN
iajs-1229	120	18	3	3	NUM
iajs-1229	120	19	6.40x10	6.40x10	NUM
iajs-1229	120	20	-3	-3	PUNCT
iajs-1229	120	21	4	4	NUM
iajs-1229	120	22	8.34x10	8.34x10	NUM
iajs-1229	120	23	-3	-3	PUNCT
iajs-1229	120	24	6	6	NUM
iajs-1229	120	25	6.68x10	6.68x10	NUM
iajs-1229	120	26	-3	-3	SYM
iajs-1229	120	27	8	8	NUM
iajs-1229	120	28	9.18x10	9.18x10	NUM
iajs-1229	120	29	-4	-4	ADP
iajs-1229	120	30	10	10	NUM
iajs-1229	120	31	7.25x10	7.25x10	NUM
iajs-1229	120	32	-5	-5	NOUN
iajs-1229	120	33	table	table	NOUN
iajs-1229	120	34	(	(	PUNCT
iajs-1229	120	35	3	3	NUM
iajs-1229	120	36	)	)	PUNCT
iajs-1229	120	37	concentration	concentration	NOUN
iajs-1229	120	38	of	of	ADP
iajs-1229	120	39	aspirin	aspirin	NOUN
iajs-1229	120	40	in	in	ADP
iajs-1229	120	41	rabbit	rabbit	NOUN
iajs-1229	120	42	blood	blood	NOUN
iajs-1229	120	43	serum	serum	NOUN
iajs-1229	121	1	[	[	X
iajs-1229	121	2	compound	compound	NOUN
iajs-1229	121	3	(	(	PUNCT
iajs-1229	121	4	3	3	NUM
iajs-1229	121	5	)	)	PUNCT
iajs-1229	121	6	]	]	PUNCT
iajs-1229	121	7	time	time	NOUN
iajs-1229	121	8	(	(	PUNCT
iajs-1229	121	9	hr	hr	NOUN
iajs-1229	121	10	)	)	PUNCT
iajs-1229	121	11	concentration	concentration	NOUN
iajs-1229	121	12	m	m	NOUN
iajs-1229	121	13	0	0	NUM
iajs-1229	121	14	0	0	NUM
iajs-1229	121	15	2	2	NUM
iajs-1229	121	16	1.47x10	1.47x10	NUM
iajs-1229	121	17	-4	-4	ADP
iajs-1229	121	18	3	3	NUM
iajs-1229	121	19	1.27x10	1.27x10	NUM
iajs-1229	121	20	-2	-2	NOUN
iajs-1229	121	21	4	4	NUM
iajs-1229	121	22	1.68x10	1.68x10	NUM
iajs-1229	121	23	-2	-2	NOUN
iajs-1229	121	24	6	6	NUM
iajs-1229	121	25	1.34x10	1.34x10	NUM
iajs-1229	121	26	-2	-2	NOUN
iajs-1229	121	27	8	8	NUM
iajs-1229	121	28	1.84x10	1.84x10	NUM
iajs-1229	121	29	-3	-3	PUNCT
iajs-1229	121	30	10	10	NUM
iajs-1229	121	31	1.46x10	1.46x10	NUM
iajs-1229	121	32	-4	-4	SYM
iajs-1229	121	33	0	0	NUM
iajs-1229	121	34	1	1	NUM
iajs-1229	121	35	2	2	NUM
iajs-1229	121	36	3	3	NUM
iajs-1229	121	37	4	4	NUM
iajs-1229	121	38	5	5	NUM
iajs-1229	121	39	6	6	NUM
iajs-1229	121	40	7	7	NUM
iajs-1229	121	41	8	8	NUM
iajs-1229	121	42	9	9	NUM
iajs-1229	121	43	2	2	NUM
iajs-1229	121	44	3	3	NUM
iajs-1229	121	45	4	4	NUM
iajs-1229	121	46	6	6	NUM
iajs-1229	121	47	8	8	NUM
iajs-1229	121	48	10	10	NUM
iajs-1229	121	49	time	time	NOUN
iajs-1229	121	50	(	(	PUNCT
iajs-1229	121	51	hr	hr	NOUN
iajs-1229	121	52	.	.	PUNCT
iajs-1229	121	53	)	)	PUNCT
iajs-1229	122	1	c	c	NOUN
iajs-1229	123	1	o	o	NOUN
iajs-1229	123	2	n	n	ADP
iajs-1229	123	3	c	c	NOUN
iajs-1229	123	4	e	e	X
iajs-1229	123	5	n	n	PART
iajs-1229	123	6	te	te	INTJ
iajs-1229	123	7	ra	ra	INTJ
iajs-1229	123	8	ti	ti	INTJ
iajs-1229	123	9	o	o	PROPN
iajs-1229	123	10	n	n	PROPN
iajs-1229	123	11	x	x	SYM
iajs-1229	123	12	1	1	NUM
iajs-1229	123	13	0	0	NUM
iajs-1229	123	14	-3	-3	PUNCT
iajs-1229	123	15	compound	compound	NOUN
iajs-1229	123	16	1	1	NUM
iajs-1229	123	17	compound	compound	NOUN
iajs-1229	123	18	2	2	NUM
iajs-1229	123	19	compound	compound	NOUN
iajs-1229	123	20	3	3	NUM
iajs-1229	123	21	fig	fig	NOUN
iajs-1229	123	22	.	.	PUNCT
iajs-1229	124	1	(	(	PUNCT
iajs-1229	124	2	1	1	NUM
iajs-1229	124	3	):	):	PUNCT
iajs-1229	124	4	concentration	concentration	NOUN
iajs-1229	124	5	of	of	ADP
iajs-1229	124	6	aspirin	aspirin	NOUN
iajs-1229	124	7	released	release	VERB