id	sid	tid	token	lemma	pos
iajs-310	1	1	microsoft	microsoft	PROPN
iajs-310	1	2	word	word	NOUN
iajs-310	1	3	12	12	NUM
iajs-310	1	4	462	462	NUM
iajs-310	2	1	|	|	ADV
iajs-310	2	2	chemistry	chemistry	NOUN
iajs-310	2	3	2014	2014	NUM
iajs-310	2	4	)	)	PUNCT
iajs-310	2	5	عام	عام	ADP
iajs-310	2	6	3(العدد	3(العدد	NUM
iajs-310	2	7	27المجلد	27المجلد	NUM
iajs-310	3	1	مجلة	مجلة	VERB
iajs-310	3	2	إبن	إبن	NOUN
iajs-310	3	3	الھيثم	الھيثم	NOUN
iajs-310	3	4	للعلوم	للعلوم	NOUN
iajs-310	3	5	الصرفة	الصرفة	NOUN
iajs-310	4	1	و	و	PRON
iajs-310	4	2	التطبيقية	التطبيقية	ADJ
iajs-310	4	3	ibn	ibn	PROPN
iajs-310	4	4	al	al	PROPN
iajs-310	4	5	-	-	PUNCT
iajs-310	4	6	haitham	haitham	PROPN
iajs-310	4	7	jour	jour	X
iajs-310	4	8	.	.	PROPN
iajs-310	4	9	for	for	ADP
iajs-310	4	10	pure	pure	ADJ
iajs-310	4	11	&	&	CCONJ
iajs-310	4	12	appl	appl	PROPN
iajs-310	4	13	.	.	PUNCT
iajs-310	5	1	sci	sci	PROPN
iajs-310	5	2	.	.	PUNCT
iajs-310	5	3	vol	vol	NOUN
iajs-310	5	4	.	.	PROPN
iajs-310	6	1	27	27	NUM
iajs-310	6	2	(	(	PUNCT
iajs-310	6	3	3	3	NUM
iajs-310	6	4	)	)	PUNCT
iajs-310	6	5	2014	2014	NUM
iajs-310	6	6	igf-1	igf-1	NOUN
iajs-310	6	7	,	,	PUNCT
iajs-310	6	8	leptin	leptin	PROPN
iajs-310	6	9	&	&	CCONJ
iajs-310	6	10	aip	aip	PROPN
iajs-310	6	11	in	in	ADP
iajs-310	6	12	relation	relation	NOUN
iajs-310	6	13	to	to	ADP
iajs-310	6	14	osteoarthritis	osteoarthritis	NOUN
iajs-310	6	15	with	with	ADP
iajs-310	6	16	and	and	CCONJ
iajs-310	6	17	without	without	ADP
iajs-310	6	18	diabetes	diabetes	NOUN
iajs-310	6	19	mellitus	mellitus	NOUN
iajs-310	6	20	type2	type2	PROPN
iajs-310	6	21	lamia	lamia	PROPN
iajs-310	6	22	s.	s.	PROPN
iajs-310	6	23	ashoor	ashoor	VERB
iajs-310	6	24	basic	basic	ADJ
iajs-310	6	25	science	science	NOUN
iajs-310	6	26	/	/	SYM
iajs-310	6	27	agriculture	agriculture	NOUN
iajs-310	6	28	collage	collage	NOUN
iajs-310	6	29	/	/	SYM
iajs-310	6	30	university	university	PROPN
iajs-310	6	31	of	of	ADP
iajs-310	6	32	baghdad	baghdad	PROPN
iajs-310	6	33	tariq	tariq	PROPN
iajs-310	6	34	m.	m.	PROPN
iajs-310	6	35	ali	ali	PROPN
iajs-310	6	36	dept	dept	PROPN
iajs-310	6	37	.	.	PROPN
iajs-310	7	1	of	of	ADP
iajs-310	7	2	chemistry	chemistry	NOUN
iajs-310	7	3	/	/	SYM
iajs-310	7	4	college	college	NOUN
iajs-310	7	5	education	education	NOUN
iajs-310	7	6	for	for	ADP
iajs-310	7	7	pure	pure	ADJ
iajs-310	7	8	science	science	NOUN
iajs-310	7	9	(	(	PUNCT
iajs-310	7	10	ibn	ibn	PROPN
iajs-310	7	11	al	al	PROPN
iajs-310	7	12	-	-	PUNCT
iajs-310	7	13	haitham	haitham	PROPN
iajs-310	7	14	)	)	PUNCT
iajs-310	7	15	/	/	SYM
iajs-310	7	16	university	university	NOUN
iajs-310	7	17	of	of	ADP
iajs-310	7	18	baghdad	baghdad	PROPN
iajs-310	7	19	hamidg	hamidg	PROPN
iajs-310	7	20	.	.	PUNCT
iajs-310	8	1	hasan	hasan	PROPN
iajs-310	8	2	clinical	clinical	ADJ
iajs-310	8	3	chemistry	chemistry	NOUN
iajs-310	8	4	department/	department/	NUM
iajs-310	8	5	al	al	PROPN
iajs-310	8	6	–	–	PUNCT
iajs-310	8	7	safwa	safwa	PROPN
iajs-310	8	8	university	university	NOUN
iajs-310	8	9	college/	college/	PROPN
iajs-310	8	10	karbala	karbala	PROPN
iajs-310	8	11	received	receive	VERB
iajs-310	8	12	in	in	ADP
iajs-310	8	13	:	:	PUNCT
iajs-310	8	14	1	1	NUM
iajs-310	8	15	september	september	PROPN
iajs-310	8	16	2014,accepted	2014,accepted	NUM
iajs-310	8	17	in	in	ADP
iajs-310	8	18	:	:	PUNCT
iajs-310	8	19	29	29	NUM
iajs-310	8	20	september	september	PROPN
iajs-310	8	21	2014	2014	NUM
iajs-310	8	22	abstract	abstract	NOUN
iajs-310	8	23	igf-1	igf-1	NOUN
iajs-310	8	24	is	be	AUX
iajs-310	8	25	a	a	DET
iajs-310	8	26	protein	protein	NOUN
iajs-310	8	27	produced	produce	VERB
iajs-310	8	28	by	by	ADP
iajs-310	8	29	the	the	DET
iajs-310	8	30	liver	liver	NOUN
iajs-310	8	31	in	in	ADP
iajs-310	8	32	response	response	NOUN
iajs-310	8	33	to	to	ADP
iajs-310	8	34	growth	growth	NOUN
iajs-310	8	35	hormone	hormone	NOUN
iajs-310	8	36	stimulus.one	stimulus.one	X
iajs-310	8	37	important	important	ADJ
iajs-310	8	38	key	key	NOUN
iajs-310	8	39	in	in	ADP
iajs-310	8	40	effectively	effectively	ADV
iajs-310	8	41	preventing	prevent	VERB
iajs-310	8	42	and	and	CCONJ
iajs-310	8	43	treating	treat	VERB
iajs-310	8	44	osteo	osteo	NOUN
iajs-310	8	45	arthritis	arthritis	NOUN
iajs-310	8	46	,	,	PUNCT
iajs-310	8	47	is	be	AUX
iajs-310	8	48	establishing	establish	VERB
iajs-310	8	49	a	a	DET
iajs-310	8	50	healthy	healthy	ADJ
iajs-310	8	51	balance	balance	NOUN
iajs-310	8	52	of	of	ADP
iajs-310	8	53	igf-1	igf-1	NOUN
iajs-310	8	54	.	.	PUNCT
iajs-310	9	1	leptin	leptin	NOUN
iajs-310	9	2	is	be	AUX
iajs-310	9	3	a	a	DET
iajs-310	9	4	hormone	hormone	NOUN
iajs-310	9	5	produced	produce	VERB
iajs-310	9	6	by	by	ADP
iajs-310	9	7	adipose	adipose	ADJ
iajs-310	9	8	tissue	tissue	NOUN
iajs-310	9	9	,	,	PUNCT
iajs-310	9	10	acting	act	VERB
iajs-310	9	11	as	as	ADP
iajs-310	9	12	a	a	DET
iajs-310	9	13	sensor	sensor	NOUN
iajs-310	9	14	of	of	ADP
iajs-310	9	15	fat	fat	ADJ
iajs-310	9	16	mass	mass	NOUN
iajs-310	9	17	in	in	ADP
iajs-310	9	18	part	part	NOUN
iajs-310	9	19	of	of	ADP
iajs-310	9	20	a	a	DET
iajs-310	9	21	negative	negative	ADJ
iajs-310	9	22	feedback	feedback	NOUN
iajs-310	9	23	loop	loop	NOUN
iajs-310	9	24	that	that	PRON
iajs-310	9	25	maintains	maintain	VERB
iajs-310	9	26	a	a	DET
iajs-310	9	27	set	set	NOUN
iajs-310	9	28	point	point	NOUN
iajs-310	9	29	for	for	ADP
iajs-310	9	30	body	body	NOUN
iajs-310	9	31	fat	fat	NOUN
iajs-310	9	32	stores	store	NOUN
iajs-310	9	33	.	.	PUNCT
iajs-310	10	1	leptin	leptin	NOUN
iajs-310	10	2	plays	play	VERB
iajs-310	10	3	an	an	DET
iajs-310	10	4	important	important	ADJ
iajs-310	10	5	role	role	NOUN
iajs-310	10	6	in	in	ADP
iajs-310	10	7	the	the	DET
iajs-310	10	8	progression	progression	NOUN
iajs-310	10	9	of	of	ADP
iajs-310	10	10	osteoarthritis	osteoarthritis	NOUN
iajs-310	10	11	(	(	PUNCT
iajs-310	10	12	oa	oa	NOUN
iajs-310	10	13	)	)	PUNCT
iajs-310	10	14	,	,	PUNCT
iajs-310	10	15	prompting	prompt	VERB
iajs-310	10	16	some	some	PRON
iajs-310	10	17	to	to	PART
iajs-310	10	18	classify	classify	VERB
iajs-310	10	19	oa	oa	PRON
iajs-310	10	20	as	as	ADP
iajs-310	10	21	a	a	DET
iajs-310	10	22	metabolic	metabolic	NOUN
iajs-310	10	23	disease	disease	NOUN
iajs-310	10	24	.	.	PUNCT
iajs-310	11	1	it	it	PRON
iajs-310	11	2	,	,	PUNCT
iajs-310	11	3	has	have	AUX
iajs-310	11	4	been	be	AUX
iajs-310	11	5	found	find	VERB
iajs-310	11	6	in	in	ADP
iajs-310	11	7	synovial	synovial	ADJ
iajs-310	11	8	fluid	fluid	NOUN
iajs-310	11	9	from	from	ADP
iajs-310	11	10	patients	patient	NOUN
iajs-310	11	11	with	with	ADP
iajs-310	11	12	oa	oa	PROPN
iajs-310	11	13	,	,	PUNCT
iajs-310	11	14	and	and	CCONJ
iajs-310	11	15	are	be	AUX
iajs-310	11	16	thought	think	VERB
iajs-310	11	17	to	to	PART
iajs-310	11	18	have	have	VERB
iajs-310	11	19	local	local	ADJ
iajs-310	11	20	effects	effect	NOUN
iajs-310	11	21	on	on	ADP
iajs-310	11	22	joint	joint	ADJ
iajs-310	11	23	tissues	tissue	NOUN
iajs-310	11	24	.	.	PUNCT
iajs-310	12	1	atherogenic	atherogenic	ADJ
iajs-310	12	2	index	index	NOUN
iajs-310	12	3	of	of	ADP
iajs-310	12	4	plasma	plasma	NOUN
iajs-310	12	5	(	(	PUNCT
iajs-310	12	6	aip	aip	PROPN
iajs-310	12	7	)	)	PUNCT
iajs-310	12	8	is	be	AUX
iajs-310	12	9	newly	newly	ADV
iajs-310	12	10	marker	marker	NOUN
iajs-310	12	11	of	of	ADP
iajs-310	12	12	atherogenectiy	atherogenectiy	PROPN
iajs-310	12	13	provide	provide	VERB
iajs-310	12	14	prediction	prediction	NOUN
iajs-310	12	15	to	to	PART
iajs-310	12	16	accelerated	accelerated	VERB
iajs-310	12	17	development	development	NOUN
iajs-310	12	18	of	of	ADP
iajs-310	12	19	atherosclerosis	atherosclerosis	NOUN
iajs-310	12	20	in	in	ADP
iajs-310	12	21	diabetes	diabetes	NOUN
iajs-310	12	22	mellitus	mellitus	NOUN
iajs-310	12	23	patients	patient	NOUN
iajs-310	12	24	.	.	PUNCT
iajs-310	13	1	objective	objective	ADJ
iajs-310	13	2	this	this	DET
iajs-310	13	3	study	study	NOUN
iajs-310	13	4	was	be	AUX
iajs-310	13	5	designed	design	VERB
iajs-310	13	6	to	to	PART
iajs-310	13	7	find	find	VERB
iajs-310	13	8	out	out	ADP
iajs-310	13	9	the	the	DET
iajs-310	13	10	variation	variation	NOUN
iajs-310	13	11	of	of	ADP
iajs-310	13	12	some	some	DET
iajs-310	13	13	parameters	parameter	NOUN
iajs-310	13	14	in	in	ADP
iajs-310	13	15	oa	oa	PROPN
iajs-310	13	16	with	with	ADP
iajs-310	13	17	&	&	CCONJ
iajs-310	13	18	without	without	ADP
iajs-310	13	19	t2	t2	PROPN
iajs-310	13	20	dm	dm	PROPN
iajs-310	13	21	.	.	PUNCT
iajs-310	14	1	patients	patient	NOUN
iajs-310	14	2	and	and	CCONJ
iajs-310	14	3	methods	method	NOUN
iajs-310	14	4	this	this	DET
iajs-310	14	5	study	study	NOUN
iajs-310	14	6	included	include	VERB
iajs-310	14	7	(	(	PUNCT
iajs-310	14	8	88	88	NUM
iajs-310	14	9	)	)	PUNCT
iajs-310	14	10	subjects	subject	NOUN
iajs-310	14	11	aged	age	VERB
iajs-310	14	12	between	between	ADP
iajs-310	14	13	(	(	PUNCT
iajs-310	14	14	40	40	NUM
iajs-310	14	15	-	-	SYM
iajs-310	14	16	60	60	NUM
iajs-310	14	17	)	)	PUNCT
iajs-310	14	18	years	year	NOUN
iajs-310	14	19	(	(	PUNCT
iajs-310	14	20	all	all	DET
iajs-310	14	21	females	female	NOUN
iajs-310	14	22	,	,	PUNCT
iajs-310	14	23	newly	newly	ADV
iajs-310	14	24	diagnoses	diagnosis	NOUN
iajs-310	14	25	and	and	CCONJ
iajs-310	14	26	obese	obese	NOUN
iajs-310	14	27	)	)	PUNCT
iajs-310	14	28	who	who	PRON
iajs-310	14	29	were	be	AUX
iajs-310	14	30	attending	attend	VERB
iajs-310	14	31	the	the	DET
iajs-310	14	32	alkadhimiya	alkadhimiya	NOUN
iajs-310	14	33	teaching	teach	VERB
iajs-310	14	34	hospital	hospital	NOUN
iajs-310	14	35	.	.	PUNCT
iajs-310	15	1	baghdad	baghdad	PROPN
iajs-310	15	2	and	and	CCONJ
iajs-310	15	3	al	al	PROPN
iajs-310	15	4	-	-	PUNCT
iajs-310	15	5	mustansiriya	mustansiriya	PROPN
iajs-310	15	6	university	university	NOUN
iajs-310	15	7	.	.	PUNCT
iajs-310	16	1	the	the	DET
iajs-310	16	2	enrolled	enrol	VERB
iajs-310	16	3	patients	patient	NOUN
iajs-310	16	4	were	be	AUX
iajs-310	16	5	divided	divide	VERB
iajs-310	16	6	to	to	ADP
iajs-310	16	7	four	four	NUM
iajs-310	16	8	groups	group	NOUN
iajs-310	16	9	:	:	PUNCT
iajs-310	16	10	oa(24	oa(24	ADJ
iajs-310	16	11	)	)	PUNCT
iajs-310	16	12	,	,	PUNCT
iajs-310	16	13	t2	t2	NOUN
iajs-310	16	14	dm	dm	PROPN
iajs-310	16	15	(	(	PUNCT
iajs-310	16	16	20	20	NUM
iajs-310	16	17	)	)	PUNCT
iajs-310	16	18	,	,	PUNCT
iajs-310	16	19	oawitht2	oawitht2	PROPN
iajs-310	17	1	dm	dm	X
iajs-310	17	2	(	(	PUNCT
iajs-310	17	3	24	24	NUM
iajs-310	17	4	)	)	PUNCT
iajs-310	17	5	and	and	CCONJ
iajs-310	17	6	control	control	NOUN
iajs-310	17	7	(	(	PUNCT
iajs-310	17	8	20	20	NUM
iajs-310	17	9	)	)	PUNCT
iajs-310	17	10	.	.	PUNCT
iajs-310	18	1	venous	venous	ADJ
iajs-310	18	2	blood	blood	NOUN
iajs-310	18	3	samples	sample	NOUN
iajs-310	18	4	from	from	ADP
iajs-310	18	5	women	woman	NOUN
iajs-310	18	6	were	be	AUX
iajs-310	18	7	taken	take	VERB
iajs-310	18	8	for	for	ADP
iajs-310	18	9	laboratory	laboratory	NOUN
iajs-310	18	10	investigation	investigation	NOUN
iajs-310	18	11	which	which	PRON
iajs-310	18	12	included	include	VERB
iajs-310	18	13	:	:	PUNCT
iajs-310	18	14	fasting	fast	VERB
iajs-310	18	15	plasma	plasma	NOUN
iajs-310	18	16	glucose	glucose	NOUN
iajs-310	18	17	,	,	PUNCT
iajs-310	18	18	lipid	lipid	NOUN
iajs-310	18	19	profile	profile	NOUN
iajs-310	18	20	(	(	PUNCT
iajs-310	18	21	tc	tc	INTJ
iajs-310	18	22	,	,	PUNCT
iajs-310	18	23	tg	tg	PROPN
iajs-310	18	24	,	,	PUNCT
iajs-310	18	25	hdlc	hdlc	PROPN
iajs-310	18	26	and	and	CCONJ
iajs-310	18	27	ldlc	ldlc	NOUN
iajs-310	18	28	)	)	PUNCT
iajs-310	18	29	,	,	PUNCT
iajs-310	18	30	igf-1	igf-1	NOUN
iajs-310	18	31	,	,	PUNCT
iajs-310	18	32	leptin	leptin	NOUN
iajs-310	18	33	were	be	AUX
iajs-310	18	34	measured	measure	VERB
iajs-310	18	35	and	and	CCONJ
iajs-310	18	36	atherogenic	atherogenic	ADJ
iajs-310	18	37	index	index	NOUN
iajs-310	18	38	of	of	ADP
iajs-310	18	39	plasma	plasma	NOUN
iajs-310	18	40	calculated	calculate	VERB
iajs-310	18	41	as	as	ADP
iajs-310	18	42	molar	molar	ADJ
iajs-310	18	43	ratio	ratio	NOUN
iajs-310	18	44	of	of	ADP
iajs-310	18	45	log	log	NOUN
iajs-310	18	46	(	(	PUNCT
iajs-310	18	47	tg/	tg/	INTJ
iajs-310	18	48	hdl	hdl	PROPN
iajs-310	18	49	-	-	PUNCT
iajs-310	18	50	c	c	NOUN
iajs-310	18	51	)	)	PUNCT
iajs-310	18	52	.	.	PUNCT
iajs-310	19	1	results	result	VERB
iajs-310	19	2	the	the	DET
iajs-310	19	3	current	current	ADJ
iajs-310	19	4	study	study	NOUN
iajs-310	19	5	shows	show	VERB
iajs-310	19	6	a	a	DET
iajs-310	19	7	significant	significant	ADJ
iajs-310	19	8	increased	increase	VERB
iajs-310	19	9	atherogenic	atherogenic	ADJ
iajs-310	19	10	index	index	NOUN
iajs-310	19	11	,	,	PUNCT
iajs-310	19	12	leptin	leptin	NOUN
iajs-310	19	13	value	value	NOUN
iajs-310	19	14	,	,	PUNCT
iajs-310	19	15	in	in	ADP
iajs-310	19	16	three	three	NUM
iajs-310	19	17	patients	patient	NOUN
iajs-310	19	18	groups	group	NOUN
iajs-310	19	19	diabetes	diabetes	NOUN
iajs-310	19	20	,	,	PUNCT
iajs-310	19	21	osteoarthritis	osteoarthritis	NOUN
iajs-310	19	22	and	and	CCONJ
iajs-310	19	23	oawith	oawith	INTJ
iajs-310	20	1	dm	dm	INTJ
iajs-310	20	2	when	when	SCONJ
iajs-310	20	3	compared	compare	VERB
iajs-310	20	4	with	with	ADP
iajs-310	20	5	control	control	NOUN
iajs-310	20	6	.	.	PUNCT
iajs-310	21	1	but	but	CCONJ
iajs-310	21	2	igf-1	igf-1	NOUN
iajs-310	21	3	level	level	NOUN
iajs-310	21	4	was	be	AUX
iajs-310	21	5	significantly	significantly	ADV
iajs-310	21	6	decreased	decrease	VERB
iajs-310	21	7	in	in	ADP
iajs-310	21	8	the	the	DET
iajs-310	21	9	three	three	NUM
iajs-310	21	10	patients	patient	NOUN
iajs-310	21	11	groups	group	NOUN
iajs-310	21	12	t2	t2	PROPN
iajs-310	21	13	dm	dm	PROPN
iajs-310	21	14	,	,	PUNCT
iajs-310	21	15	oa	oa	INTJ
iajs-310	21	16	,	,	PUNCT
iajs-310	21	17	t2	t2	NOUN
iajs-310	21	18	dm	dm	NOUN
iajs-310	21	19	with	with	ADP
iajs-310	21	20	oa	oa	PRON
iajs-310	21	21	when	when	SCONJ
iajs-310	21	22	compared	compare	VERB
iajs-310	21	23	with	with	ADP
iajs-310	21	24	control	control	NOUN
iajs-310	21	25	.	.	PUNCT
iajs-310	22	1	conclusion	conclusion	NOUN
iajs-310	22	2	osteoarthritis	osteoarthritis	NOUN
iajs-310	22	3	has	have	VERB
iajs-310	22	4	a	a	DET
iajs-310	22	5	direct	direct	ADJ
iajs-310	22	6	effect	effect	NOUN
iajs-310	22	7	on	on	ADP
iajs-310	22	8	dislipidemia	dislipidemia	NOUN
iajs-310	22	9	,	,	PUNCT
iajs-310	22	10	leptin	leptin	PROPN
iajs-310	22	11	&	&	CCONJ
iajs-310	22	12	aip	aip	PROPN
iajs-310	22	13	value	value	NOUN
iajs-310	22	14	in	in	ADP
iajs-310	22	15	diabetes	diabetes	NOUN
iajs-310	22	16	mellitus	mellitus	PROPN
iajs-310	22	17	type2	type2	PROPN
iajs-310	22	18	key	key	ADJ
iajs-310	22	19	words	word	NOUN
iajs-310	22	20	:	:	PUNCT
iajs-310	22	21	osteoarthritis	osteoarthritis	NOUN
iajs-310	22	22	,	,	PUNCT
iajs-310	22	23	aip	aip	PROPN
iajs-310	22	24	,	,	PUNCT
iajs-310	22	25	leptin	leptin	NOUN
iajs-310	22	26	,	,	PUNCT
iajs-310	22	27	t2	t2	PROPN
iajs-310	22	28	dm	dm	PROPN
iajs-310	22	29	,	,	PUNCT
iajs-310	22	30	igf-1	igf-1	NOUN
iajs-310	22	31	463	463	NUM
iajs-310	23	1	|	|	ADV
iajs-310	23	2	chemistry	chemistry	NOUN
iajs-310	23	3	2014	2014	NUM
iajs-310	23	4	)	)	PUNCT
iajs-310	23	5	عام	عام	ADP
iajs-310	23	6	3(العدد	3(العدد	NUM
iajs-310	23	7	27المجلد	27المجلد	NUM
iajs-310	23	8	مجلة	مجلة	VERB
iajs-310	23	9	إبن	إبن	NOUN
iajs-310	23	10	الھيثم	الھيثم	NOUN
iajs-310	23	11	للعلوم	للعلوم	NOUN
iajs-310	23	12	الصرفة	الصرفة	NOUN
iajs-310	24	1	و	و	PRON
iajs-310	24	2	التطبيقية	التطبيقية	ADJ
iajs-310	24	3	ibn	ibn	PROPN
iajs-310	24	4	al	al	PROPN
iajs-310	24	5	-	-	PUNCT
iajs-310	24	6	haitham	haitham	PROPN
iajs-310	24	7	jour	jour	X
iajs-310	24	8	.	.	PROPN
iajs-310	24	9	for	for	ADP
iajs-310	24	10	pure	pure	ADJ
iajs-310	24	11	&	&	CCONJ
iajs-310	24	12	appl	appl	PROPN
iajs-310	24	13	.	.	PUNCT
iajs-310	25	1	sci	sci	PROPN
iajs-310	25	2	.	.	PUNCT
iajs-310	25	3	vol	vol	NOUN
iajs-310	25	4	.	.	PROPN
iajs-310	26	1	27	27	NUM
iajs-310	26	2	(	(	PUNCT
iajs-310	26	3	3	3	NUM
iajs-310	26	4	)	)	PUNCT
iajs-310	26	5	2014	2014	NUM
iajs-310	26	6	introduction	introduction	NOUN
iajs-310	26	7	osteoarthritis	osteoarthritis	NOUN
iajs-310	26	8	(	(	PUNCT
iajs-310	26	9	oa	oa	NOUN
iajs-310	26	10	)	)	PUNCT
iajs-310	26	11	,	,	PUNCT
iajs-310	26	12	is	be	AUX
iajs-310	26	13	a	a	DET
iajs-310	26	14	chronic	chronic	ADJ
iajs-310	26	15	disease	disease	NOUN
iajs-310	26	16	,	,	PUNCT
iajs-310	26	17	resulted	result	VERB
iajs-310	26	18	in	in	ADP
iajs-310	26	19	patient	patient	NOUN
iajs-310	26	20	suffers	suffer	NOUN
iajs-310	26	21	from	from	ADP
iajs-310	26	22	harmful	harmful	ADJ
iajs-310	26	23	changes	change	NOUN
iajs-310	26	24	in	in	ADP
iajs-310	26	25	cartilage	cartilage	NOUN
iajs-310	26	26	,	,	PUNCT
iajs-310	26	27	bone	bone	NOUN
iajs-310	26	28	,	,	PUNCT
iajs-310	26	29	ligaments	ligament	NOUN
iajs-310	26	30	and	and	CCONJ
iajs-310	26	31	muscles	muscle	NOUN
iajs-310	26	32	.	.	PUNCT
iajs-310	27	1	osteoarthritis	osteoarthritis	NOUN
iajs-310	27	2	is	be	AUX
iajs-310	27	3	not	not	PART
iajs-310	27	4	a	a	DET
iajs-310	27	5	single	single	ADJ
iajs-310	27	6	,	,	PUNCT
iajs-310	27	7	well	well	ADV
iajs-310	27	8	-	-	PUNCT
iajs-310	27	9	define	define	VERB
iajs-310	27	10	disease	disease	NOUN
iajs-310	27	11	condition	condition	NOUN
iajs-310	27	12	but	but	CCONJ
iajs-310	27	13	is	be	AUX
iajs-310	27	14	best	well	ADV
iajs-310	27	15	described	describe	VERB
iajs-310	27	16	as	as	ADP
iajs-310	27	17	a	a	DET
iajs-310	27	18	final	final	ADJ
iajs-310	27	19	stage	stage	NOUN
iajs-310	27	20	failure	failure	NOUN
iajs-310	27	21	of	of	ADP
iajs-310	27	22	the	the	DET
iajs-310	27	23	joints	joint	NOUN
iajs-310	27	24	that	that	PRON
iajs-310	27	25	presents	present	VERB
iajs-310	27	26	similar	similar	ADJ
iajs-310	27	27	symptoms	symptom	NOUN
iajs-310	27	28	and	and	CCONJ
iajs-310	27	29	radiographic	radiographic	ADJ
iajs-310	27	30	findings	finding	NOUN
iajs-310	27	31	regardless	regardless	ADV
iajs-310	27	32	of	of	ADP
iajs-310	27	33	the	the	DET
iajs-310	27	34	original	original	ADJ
iajs-310	27	35	cause	cause	NOUN
iajs-310	27	36	[	[	X
iajs-310	27	37	1],.the	1],.the	DET
iajs-310	27	38	question	question	NOUN
iajs-310	27	39	that	that	PRON
iajs-310	27	40	arises	arise	VERB
iajs-310	27	41	is	be	AUX
iajs-310	27	42	does	do	AUX
iajs-310	27	43	diabetes	diabetes	NOUN
iajs-310	27	44	inhibit	inhibit	VERB
iajs-310	27	45	osteoarthritis	osteoarthritis	NOUN
iajs-310	27	46	pain	pain	NOUN
iajs-310	27	47	?	?	PUNCT
iajs-310	28	1	it	it	PRON
iajs-310	28	2	was	be	AUX
iajs-310	28	3	proved	prove	VERB
iajs-310	28	4	that	that	SCONJ
iajs-310	28	5	neuropathy	neuropathy	ADJ
iajs-310	28	6	caused	cause	VERB
iajs-310	28	7	by	by	ADP
iajs-310	28	8	impaired	impaired	ADJ
iajs-310	28	9	glucose	glucose	NOUN
iajs-310	28	10	tolerance	tolerance	NOUN
iajs-310	28	11	/	/	PUNCT
iajs-310	28	12	diabetes	diabetes	NOUN
iajs-310	28	13	mellitus	mellitus	NOUN
iajs-310	28	14	inhibit	inhibit	VERB
iajs-310	28	15	the	the	DET
iajs-310	28	16	expression	expression	NOUN
iajs-310	28	17	of	of	ADP
iajs-310	28	18	pain	pain	NOUN
iajs-310	28	19	due	due	ADP
iajs-310	28	20	to	to	ADP
iajs-310	28	21	osteoarthritis	osteoarthritis	NOUN
iajs-310	28	22	in	in	ADP
iajs-310	28	23	the	the	DET
iajs-310	28	24	lower	low	ADJ
iajs-310	28	25	extremities	extremity	NOUN
iajs-310	28	26	among	among	ADP
iajs-310	28	27	a	a	DET
iajs-310	28	28	portion	portion	NOUN
iajs-310	28	29	of	of	ADP
iajs-310	28	30	patients	patient	NOUN
iajs-310	28	31	displaying	display	VERB
iajs-310	28	32	radiographic	radiographic	ADJ
iajs-310	28	33	osteoarthritis	osteoarthritis	NOUN
iajs-310	29	1	[	[	X
iajs-310	29	2	2	2	NUM
iajs-310	29	3	]	]	PUNCT
iajs-310	29	4	.	.	PUNCT
iajs-310	30	1	both	both	DET
iajs-310	30	2	oa	oa	X
iajs-310	30	3	and	and	CCONJ
iajs-310	30	4	dm	dm	PROPN
iajs-310	30	5	can	can	AUX
iajs-310	30	6	be	be	AUX
iajs-310	30	7	viewed	view	VERB
iajs-310	30	8	as	as	ADP
iajs-310	30	9	chronic	chronic	ADJ
iajs-310	30	10	disease	disease	NOUN
iajs-310	30	11	processes	process	NOUN
iajs-310	30	12	characterized	characterize	VERB
iajs-310	30	13	by	by	ADP
iajs-310	30	14	earl	earl	PROPN
iajs-310	30	15	,	,	PUNCT
iajs-310	30	16	undetected	undetected	ADJ
iajs-310	30	17	levels	level	NOUN
iajs-310	30	18	of	of	ADP
iajs-310	30	19	biological	biological	ADJ
iajs-310	30	20	change	change	NOUN
iajs-310	30	21	.	.	PUNCT
iajs-310	31	1	some	some	PRON
iajs-310	31	2	of	of	ADP
iajs-310	31	3	the	the	DET
iajs-310	31	4	studies	study	NOUN
iajs-310	31	5	of	of	ADP
iajs-310	31	6	the	the	DET
iajs-310	31	7	association	association	NOUN
iajs-310	31	8	between	between	ADP
iajs-310	31	9	oa	oa	PROPN
iajs-310	31	10	and	and	CCONJ
iajs-310	31	11	dm	dm	PROPN
iajs-310	31	12	,	,	PUNCT
iajs-310	31	13	examined	examine	VERB
iajs-310	31	14	a	a	DET
iajs-310	31	15	variety	variety	NOUN
iajs-310	31	16	of	of	ADP
iajs-310	31	17	relevant	relevant	ADJ
iajs-310	31	18	factors	factor	NOUN
iajs-310	31	19	,	,	PUNCT
iajs-310	31	20	such	such	ADJ
iajs-310	31	21	as	as	ADP
iajs-310	31	22	leptin	leptin	NOUN
iajs-310	31	23	,	,	PUNCT
iajs-310	31	24	aip	aip	PROPN
iajs-310	31	25	,	,	PUNCT
iajs-310	31	26	insulin	insulin	NOUN
iajs-310	31	27	-	-	PUNCT
iajs-310	31	28	like	like	ADJ
iajs-310	31	29	growth	growth	NOUN
iajs-310	31	30	factor	factor	NOUN
iajs-310	31	31	1	1	NUM
iajs-310	31	32	(	(	PUNCT
iajs-310	31	33	igf-1)	igf-1)	PROPN
iajs-310	31	34	…	…	NUM
iajs-310	31	35	etc[3,4,5	etc[3,4,5	ADJ
iajs-310	31	36	]	]	PUNCT
iajs-310	31	37	.	.	PUNCT
iajs-310	32	1	atherogenic	atherogenic	ADJ
iajs-310	32	2	index	index	NOUN
iajs-310	32	3	of	of	ADP
iajs-310	32	4	plasma	plasma	NOUN
iajs-310	32	5	(	(	PUNCT
iajs-310	32	6	aip	aip	PROPN
iajs-310	32	7	)	)	PUNCT
iajs-310	32	8	defined	define	VERB
iajs-310	32	9	as	as	ADP
iajs-310	32	10	log	log	NOUN
iajs-310	32	11	(	(	PUNCT
iajs-310	32	12	tg	tg	PROPN
iajs-310	32	13	/	/	SYM
iajs-310	32	14	hdl	hdl	PROPN
iajs-310	32	15	-	-	PUNCT
iajs-310	32	16	c	c	NOUN
iajs-310	32	17	)	)	PUNCT
iajs-310	32	18	,	,	PUNCT
iajs-310	32	19	has	have	AUX
iajs-310	32	20	been	be	AUX
iajs-310	32	21	proposed	propose	VERB
iajs-310	32	22	as	as	ADP
iajs-310	32	23	a	a	DET
iajs-310	32	24	marker	marker	NOUN
iajs-310	32	25	of	of	ADP
iajs-310	32	26	plasma	plasma	NOUN
iajs-310	32	27	atherogenicity	atherogenicity	NOUN
iajs-310	32	28	because	because	SCONJ
iajs-310	32	29	it	it	PRON
iajs-310	32	30	is	be	AUX
iajs-310	32	31	increased	increase	VERB
iajs-310	32	32	in	in	ADP
iajs-310	32	33	people	people	NOUN
iajs-310	32	34	at	at	ADP
iajs-310	32	35	higher	high	ADJ
iajs-310	32	36	risk	risk	NOUN
iajs-310	32	37	for	for	ADP
iajs-310	32	38	coronary	coronary	ADJ
iajs-310	32	39	heart	heart	NOUN
iajs-310	32	40	disease	disease	NOUN
iajs-310	32	41	and	and	CCONJ
iajs-310	32	42	is	be	AUX
iajs-310	32	43	correlated	correlate	VERB
iajs-310	32	44	with	with	ADP
iajs-310	32	45	ldl	ldl	NOUN
iajs-310	32	46	particle	particle	NOUN
iajs-310	32	47	size.[6	size.[6	VERB
iajs-310	32	48	]	]	PUNCT
iajs-310	32	49	although	although	SCONJ
iajs-310	32	50	hdl	hdl	PROPN
iajs-310	32	51	in	in	ADP
iajs-310	32	52	fact	fact	NOUN
iajs-310	32	53	may	may	AUX
iajs-310	32	54	be	be	AUX
iajs-310	32	55	directly	directly	ADV
iajs-310	32	56	antiatherogenic	antiatherogenic	ADJ
iajs-310	32	57	,	,	PUNCT
iajs-310	32	58	it	it	PRON
iajs-310	32	59	also	also	ADV
iajs-310	32	60	is	be	AUX
iajs-310	32	61	a	a	DET
iajs-310	32	62	marker	marker	NOUN
iajs-310	32	63	for	for	ADP
iajs-310	32	64	the	the	DET
iajs-310	32	65	presence	presence	NOUN
iajs-310	32	66	of	of	ADP
iajs-310	32	67	other	other	ADJ
iajs-310	32	68	lipid	lipid	NOUN
iajs-310	32	69	and	and	CCONJ
iajs-310	32	70	nonlipid	nonlipid	ADJ
iajs-310	32	71	risk	risk	NOUN
iajs-310	32	72	factors	factor	NOUN
iajs-310	32	73	.	.	PUNCT
iajs-310	33	1	however	however	ADV
iajs-310	33	2	,	,	PUNCT
iajs-310	33	3	the	the	DET
iajs-310	33	4	presence	presence	NOUN
iajs-310	33	5	of	of	ADP
iajs-310	33	6	a	a	DET
iajs-310	33	7	low	low	ADJ
iajs-310	33	8	hdl	hdl	NOUN
iajs-310	33	9	level	level	NOUN
iajs-310	33	10	carries	carry	VERB
iajs-310	33	11	strong	strong	ADJ
iajs-310	33	12	predictive	predictive	ADJ
iajs-310	33	13	power	power	NOUN
iajs-310	33	14	for	for	ADP
iajs-310	33	15	development	development	NOUN
iajs-310	33	16	of	of	ADP
iajs-310	33	17	atherosclerotic	atherosclerotic	ADJ
iajs-310	33	18	cardio	cardio	NOUN
iajs-310	33	19	vascular	vascular	NOUN
iajs-310	33	20	disease	disease	NOUN
iajs-310	33	21	ascvd	ascvd	NOUN
iajs-310	33	22	.	.	PUNCT
iajs-310	34	1	[	[	X
iajs-310	34	2	7	7	X
iajs-310	34	3	]	]	X
iajs-310	34	4	the	the	DET
iajs-310	34	5	serum	serum	NOUN
iajs-310	34	6	tc	tc	PROPN
iajs-310	34	7	and	and	CCONJ
iajs-310	34	8	hdl	hdl	PROPN
iajs-310	34	9	-	-	PUNCT
iajs-310	34	10	c	c	PROPN
iajs-310	34	11	levels	level	NOUN
iajs-310	34	12	in	in	ADP
iajs-310	34	13	knee	knee	NOUN
iajs-310	34	14	oa	oa	PRON
iajs-310	34	15	were	be	AUX
iajs-310	34	16	inversely	inversely	ADV
iajs-310	34	17	correlated	correlate	VERB
iajs-310	34	18	with	with	ADP
iajs-310	34	19	disease	disease	NOUN
iajs-310	34	20	activity	activity	NOUN
iajs-310	34	21	,	,	PUNCT
iajs-310	34	22	suggesting	suggest	VERB
iajs-310	34	23	a	a	DET
iajs-310	34	24	potential	potential	ADJ
iajs-310	34	25	role	role	NOUN
iajs-310	34	26	of	of	ADP
iajs-310	34	27	inflammation	inflammation	NOUN
iajs-310	34	28	in	in	ADP
iajs-310	34	29	the	the	DET
iajs-310	34	30	atherogenic	atherogenic	ADJ
iajs-310	34	31	profile	profile	NOUN
iajs-310	34	32	and	and	CCONJ
iajs-310	34	33	the	the	DET
iajs-310	34	34	higher	high	ADJ
iajs-310	34	35	atherosclerotic	atherosclerotic	ADJ
iajs-310	34	36	risk	risk	NOUN
iajs-310	34	37	in	in	ADP
iajs-310	34	38	arthritic	arthritic	ADJ
iajs-310	34	39	patients.[8	patients.[8	NOUN
iajs-310	34	40	]	]	X
iajs-310	34	41	igf	igf	PROPN
iajs-310	34	42	-	-	PROPN
iajs-310	34	43	i	i	PROPN
iajs-310	34	44	levels	level	NOUN
iajs-310	34	45	play	play	VERB
iajs-310	34	46	a	a	DET
iajs-310	34	47	role	role	NOUN
iajs-310	34	48	in	in	ADP
iajs-310	34	49	the	the	DET
iajs-310	34	50	development	development	NOUN
iajs-310	34	51	of	of	ADP
iajs-310	34	52	the	the	DET
iajs-310	34	53	vascular	vascular	ADJ
iajs-310	34	54	complications	complication	NOUN
iajs-310	34	55	of	of	ADP
iajs-310	34	56	type	type	NOUN
iajs-310	34	57	2	2	NUM
iajs-310	34	58	diabetes	diabetes	NOUN
iajs-310	34	59	.	.	PUNCT
iajs-310	35	1	igf	igf	PROPN
iajs-310	35	2	-	-	PROPN
iajs-310	35	3	i	i	PRON
iajs-310	35	4	may	may	AUX
iajs-310	35	5	also	also	ADV
iajs-310	35	6	play	play	VERB
iajs-310	35	7	a	a	DET
iajs-310	35	8	role	role	NOUN
iajs-310	35	9	in	in	ADP
iajs-310	35	10	the	the	DET
iajs-310	35	11	regulation	regulation	NOUN
iajs-310	35	12	of	of	ADP
iajs-310	35	13	cardiovascular	cardiovascular	ADJ
iajs-310	35	14	function	function	NOUN
iajs-310	35	15	and	and	CCONJ
iajs-310	35	16	development	development	NOUN
iajs-310	35	17	of	of	ADP
iajs-310	35	18	myocardial	myocardial	ADJ
iajs-310	35	19	infarction	infarction	NOUN
iajs-310	35	20	in	in	ADP
iajs-310	35	21	subjects	subject	NOUN
iajs-310	35	22	without	without	ADP
iajs-310	35	23	type	type	NOUN
iajs-310	35	24	2	2	NUM
iajs-310	35	25	diabetes	diabetes	NOUN
iajs-310	35	26	,	,	PUNCT
iajs-310	35	27	igf1	igf1	PROPN
iajs-310	35	28	is	be	AUX
iajs-310	35	29	regulated	regulate	VERB
iajs-310	35	30	by	by	ADP
iajs-310	35	31	multiple	multiple	ADJ
iajs-310	35	32	mechanisms	mechanism	NOUN
iajs-310	35	33	that	that	PRON
iajs-310	35	34	are	be	AUX
iajs-310	35	35	known	know	VERB
iajs-310	35	36	to	to	PART
iajs-310	35	37	regulate	regulate	VERB
iajs-310	35	38	systemic	systemic	ADJ
iajs-310	35	39	growth.[7	growth.[7	NOUN
iajs-310	35	40	]	]	PUNCT
iajs-310	35	41	igf-1	igf-1	NOUN
iajs-310	35	42	and	and	CCONJ
iajs-310	35	43	diabetes	diabetes	NOUN
iajs-310	35	44	has	have	VERB
iajs-310	35	45	a	a	DET
iajs-310	35	46	strong	strong	ADJ
iajs-310	35	47	physiological	physiological	ADJ
iajs-310	35	48	basis	basis	NOUN
iajs-310	35	49	.	.	PUNCT
iajs-310	36	1	its	its	PRON
iajs-310	36	2	level	level	NOUN
iajs-310	36	3	was	be	AUX
iajs-310	36	4	reduced	reduce	VERB
iajs-310	36	5	in	in	ADP
iajs-310	36	6	diabetes	diabetes	NOUN
iajs-310	36	7	mellitus	mellitus	NOUN
iajs-310	36	8	and	and	CCONJ
iajs-310	36	9	oxidation	oxidation	NOUN
iajs-310	36	10	stress	stress	NOUN
iajs-310	36	11	,	,	PUNCT
iajs-310	36	12	[	[	X
iajs-310	36	13	9	9	NUM
iajs-310	36	14	]	]	X
iajs-310	36	15	igf	igf	PROPN
iajs-310	36	16	and	and	CCONJ
iajs-310	36	17	insulin	insulin	NOUN
iajs-310	36	18	are	be	AUX
iajs-310	36	19	linked	link	VERB
iajs-310	36	20	hormones	hormone	NOUN
iajs-310	36	21	that	that	PRON
iajs-310	36	22	diverged	diverge	VERB
iajs-310	36	23	in	in	ADP
iajs-310	36	24	evolution.[10	evolution.[10	NOUN
iajs-310	36	25	]	]	PUNCT
iajs-310	36	26	igf-1	igf-1	PRON
iajs-310	36	27	provides	provide	VERB
iajs-310	36	28	important	important	ADJ
iajs-310	36	29	information	information	NOUN
iajs-310	36	30	about	about	ADP
iajs-310	36	31	the	the	DET
iajs-310	36	32	body	body	NOUN
iajs-310	36	33	's	's	PART
iajs-310	36	34	levels	level	NOUN
iajs-310	36	35	of	of	ADP
iajs-310	36	36	this	this	DET
iajs-310	36	37	crucial	crucial	ADJ
iajs-310	36	38	hormonal	hormonal	ADJ
iajs-310	36	39	mediator	mediator	NOUN
iajs-310	36	40	in	in	ADP
iajs-310	36	41	osteo	osteo	NOUN
iajs-310	36	42	arthritis	arthritis	NOUN
iajs-310	36	43	,	,	PUNCT
iajs-310	36	44	and	and	CCONJ
iajs-310	36	45	also	also	ADV
iajs-310	36	46	helps	help	VERB
iajs-310	36	47	assess	assess	VERB
iajs-310	36	48	the	the	DET
iajs-310	36	49	general	general	ADJ
iajs-310	36	50	functioning	function	VERB
iajs-310	36	51	integrity	integrity	NOUN
iajs-310	36	52	and	and	CCONJ
iajs-310	36	53	homeostasis	homeostasis	NOUN
iajs-310	36	54	of	of	ADP
iajs-310	36	55	the	the	DET
iajs-310	36	56	nervous	nervous	ADJ
iajs-310	36	57	system.[7	system.[7	NOUN
iajs-310	36	58	]	]	PUNCT
iajs-310	36	59	leptin	leptin	NOUN
iajs-310	36	60	regulates	regulate	VERB
iajs-310	36	61	energy	energy	NOUN
iajs-310	36	62	homeostasis	homeostasis	NOUN
iajs-310	36	63	and	and	CCONJ
iajs-310	36	64	interferes	interfere	VERB
iajs-310	36	65	with	with	ADP
iajs-310	36	66	several	several	ADJ
iajs-310	36	67	neuroendocrine	neuroendocrine	ADJ
iajs-310	36	68	and	and	CCONJ
iajs-310	36	69	immune	immune	ADJ
iajs-310	36	70	functions	function	NOUN
iajs-310	36	71	.	.	PUNCT
iajs-310	37	1	a	a	DET
iajs-310	37	2	higher	high	ADJ
iajs-310	37	3	amount	amount	NOUN
iajs-310	37	4	of	of	ADP
iajs-310	37	5	leptin	leptin	NOUN
iajs-310	37	6	is	be	AUX
iajs-310	37	7	secreted	secrete	VERB
iajs-310	37	8	by	by	ADP
iajs-310	37	9	subcutaneous	subcutaneous	ADJ
iajs-310	37	10	adipocytes	adipocyte	NOUN
iajs-310	37	11	than	than	ADP
iajs-310	37	12	by	by	ADP
iajs-310	37	13	the	the	DET
iajs-310	37	14	visceral	visceral	ADJ
iajs-310	37	15	adipocytes	adipocyte	NOUN
iajs-310	37	16	.	.	PUNCT
iajs-310	38	1	leptin	leptin	NOUN
iajs-310	38	2	is	be	AUX
iajs-310	38	3	generally	generally	ADV
iajs-310	38	4	synthesized	synthesize	VERB
iajs-310	38	5	and	and	CCONJ
iajs-310	38	6	secreted	secrete	VERB
iajs-310	38	7	by	by	ADP
iajs-310	38	8	gastric	gastric	ADJ
iajs-310	38	9	chief	chief	ADJ
iajs-310	38	10	cells	cell	NOUN
iajs-310	38	11	in	in	ADP
iajs-310	38	12	the	the	DET
iajs-310	38	13	stomach.[11	stomach.[11	NOUN
iajs-310	38	14	]	]	PUNCT
iajs-310	38	15	leptin	leptin	NOUN
iajs-310	38	16	circulating	circulate	VERB
iajs-310	38	17	levels	level	NOUN
iajs-310	38	18	are	be	AUX
iajs-310	38	19	directly	directly	ADV
iajs-310	38	20	proportional	proportional	ADJ
iajs-310	38	21	to	to	ADP
iajs-310	38	22	the	the	DET
iajs-310	38	23	body	body	NOUN
iajs-310	38	24	fat	fat	ADJ
iajs-310	38	25	.	.	PUNCT
iajs-310	39	1	.[12	.[12	PUNCT
iajs-310	39	2	]	]	PUNCT
iajs-310	39	3	it	it	PRON
iajs-310	39	4	has	have	VERB
iajs-310	39	5	a	a	DET
iajs-310	39	6	fundamental	fundamental	ADJ
iajs-310	39	7	role	role	NOUN
iajs-310	39	8	in	in	ADP
iajs-310	39	9	the	the	DET
iajs-310	39	10	control	control	NOUN
iajs-310	39	11	of	of	ADP
iajs-310	39	12	appetite	appetite	NOUN
iajs-310	39	13	and	and	CCONJ
iajs-310	39	14	also	also	ADV
iajs-310	39	15	in	in	ADP
iajs-310	39	16	regulating	regulate	VERB
iajs-310	39	17	energy	energy	NOUN
iajs-310	39	18	expenditures.[13	expenditures.[13	PROPN
iajs-310	39	19	]	]	PUNCT
iajs-310	39	20	osteoarthritis	osteoarthritis	NOUN
iajs-310	39	21	is	be	AUX
iajs-310	39	22	a	a	DET
iajs-310	39	23	metabolic	metabolic	NOUN
iajs-310	39	24	disease	disease	NOUN
iajs-310	39	25	induced	induce	VERB
iajs-310	39	26	by	by	ADP
iajs-310	39	27	local	local	ADJ
iajs-310	39	28	abnormal	abnormal	ADJ
iajs-310	39	29	leptin	leptin	NOUN
iajs-310	39	30	activity	activity	NOUN
iajs-310	39	31	.	.	PUNCT
iajs-310	40	1	a	a	DET
iajs-310	40	2	proinflammatory	proinflammatory	ADJ
iajs-310	40	3	effect	effect	NOUN
iajs-310	40	4	of	of	ADP
iajs-310	40	5	leptin	leptin	NOUN
iajs-310	40	6	on	on	ADP
iajs-310	40	7	cartilage	cartilage	NOUN
iajs-310	40	8	would	would	AUX
iajs-310	40	9	be	be	AUX
iajs-310	40	10	in	in	ADP
iajs-310	40	11	keeping	keep	VERB
iajs-310	40	12	with	with	ADP
iajs-310	40	13	the	the	DET
iajs-310	40	14	fact	fact	NOUN
iajs-310	40	15	that	that	SCONJ
iajs-310	40	16	,	,	PUNCT
iajs-310	40	17	in	in	ADP
iajs-310	40	18	comparison	comparison	NOUN
iajs-310	40	19	with	with	ADP
iajs-310	40	20	men	man	NOUN
iajs-310	40	21	,	,	PUNCT
iajs-310	40	22	women	woman	NOUN
iajs-310	40	23	have	have	AUX
iajs-310	40	24	both	both	CCONJ
iajs-310	40	25	higher	high	ADJ
iajs-310	40	26	circulating	circulate	VERB
iajs-310	40	27	leptin	leptin	NOUN
iajs-310	40	28	levels	level	NOUN
iajs-310	40	29	and	and	CCONJ
iajs-310	40	30	a	a	DET
iajs-310	40	31	greater	great	ADJ
iajs-310	40	32	propensity	propensity	NOUN
iajs-310	40	33	to	to	PART
iajs-310	40	34	develop	develop	VERB
iajs-310	40	35	osteoarthritis.[14	osteoarthritis.[14	PROPN
iajs-310	40	36	]	]	PUNCT
iajs-310	40	37	materials	material	NOUN
iajs-310	40	38	and	and	CCONJ
iajs-310	40	39	methods	method	NOUN
iajs-310	40	40	the	the	DET
iajs-310	40	41	study	study	NOUN
iajs-310	40	42	was	be	AUX
iajs-310	40	43	conducted	conduct	VERB
iajs-310	40	44	at	at	ADP
iajs-310	40	45	alkadhimiya	alkadhimiya	NOUN
iajs-310	40	46	teaching	teach	VERB
iajs-310	40	47	hospital	hospital	NOUN
iajs-310	40	48	.	.	PUNCT
iajs-310	41	1	baghdad	baghdad	PROPN
iajs-310	41	2	,	,	PUNCT
iajs-310	41	3	and	and	CCONJ
iajs-310	41	4	department	department	NOUN
iajs-310	41	5	of	of	ADP
iajs-310	41	6	national	national	ADJ
iajs-310	41	7	diabetes	diabetes	NOUN
iajs-310	41	8	center	center	NOUN
iajs-310	41	9	for	for	ADP
iajs-310	41	10	treatment	treatment	NOUN
iajs-310	41	11	research	research	NOUN
iajs-310	41	12	at	at	ADP
iajs-310	41	13	al	al	PROPN
iajs-310	41	14	-	-	PUNCT
iajs-310	41	15	mustansiriya	mustansiriya	PROPN
iajs-310	41	16	university	university	NOUN
iajs-310	41	17	.	.	PUNCT
iajs-310	42	1	(	(	PUNCT
iajs-310	42	2	88	88	NUM
iajs-310	42	3	)	)	PUNCT
iajs-310	42	4	patient	patient	ADJ
iajs-310	42	5	subjects	subject	NOUN
iajs-310	42	6	were	be	AUX
iajs-310	42	7	enrolled	enrol	VERB
iajs-310	42	8	osteoarthritis	osteoarthritis	NOUN
iajs-310	42	9	and	and	CCONJ
iajs-310	42	10	type	type	NOUN
iajs-310	42	11	2	2	NUM
iajs-310	42	12	diabetes	diabetes	NOUN
iajs-310	42	13	mellitus	mellitus	NOUN
iajs-310	42	14	(	(	PUNCT
iajs-310	42	15	t2	t2	NOUN
iajs-310	42	16	dm	dm	PROPN
iajs-310	42	17	)	)	PUNCT
iajs-310	42	18	patients,(all	patients,(all	NOUN
iajs-310	42	19	females	female	NOUN
iajs-310	42	20	,	,	PUNCT
iajs-310	42	21	newly	newly	ADV
iajs-310	42	22	diagnoses	diagnosis	NOUN
iajs-310	42	23	and	and	CCONJ
iajs-310	42	24	obese	obese	NOUN
iajs-310	42	25	)	)	PUNCT
iajs-310	42	26	,	,	PUNCT
iajs-310	42	27	the	the	DET
iajs-310	42	28	age	age	NOUN
iajs-310	42	29	range	range	NOUN
iajs-310	42	30	was	be	AUX
iajs-310	42	31	within	within	ADP
iajs-310	42	32	(	(	PUNCT
iajs-310	42	33	40	40	NUM
iajs-310	42	34	-	-	SYM
iajs-310	42	35	60	60	NUM
iajs-310	42	36	years),(68	years),(68	NOUN
iajs-310	42	37	)	)	PUNCT
iajs-310	42	38	divided	divide	VERB
iajs-310	42	39	into	into	ADP
iajs-310	42	40	three	three	NUM
iajs-310	42	41	groups	group	NOUN
iajs-310	42	42	.	.	PUNCT
iajs-310	43	1	and	and	CCONJ
iajs-310	43	2	control	control	PROPN
iajs-310	43	3	group	group	NOUN
iajs-310	43	4	(	(	PUNCT
iajs-310	43	5	20	20	NUM
iajs-310	43	6	)	)	PUNCT
iajs-310	43	7	subjects	subject	NOUN
iajs-310	43	8	.	.	PUNCT
iajs-310	44	1	blood	blood	NOUN
iajs-310	44	2	samples	sample	NOUN
iajs-310	44	3	taken	take	VERB
iajs-310	44	4	for	for	ADP
iajs-310	44	5	laboratory	laboratory	NOUN
iajs-310	44	6	investigation	investigation	NOUN
iajs-310	44	7	which	which	PRON
iajs-310	44	8	included	include	VERB
iajs-310	44	9	,	,	PUNCT
iajs-310	44	10	fasting	fast	VERB
iajs-310	44	11	blood	blood	NOUN
iajs-310	44	12	sugar	sugar	NOUN
iajs-310	44	13	,	,	PUNCT
iajs-310	44	14	lipid	lipid	NOUN
iajs-310	44	15	profile	profile	NOUN
iajs-310	44	16	(	(	PUNCT
iajs-310	44	17	total	total	ADJ
iajs-310	44	18	colesterol	colesterol	PROPN
iajs-310	44	19	,	,	PUNCT
iajs-310	44	20	triglyceride	triglyceride	ADJ
iajs-310	44	21	,	,	PUNCT
iajs-310	44	22	high	high	ADJ
iajs-310	44	23	density	density	NOUN
iajs-310	44	24	lipoprotein	lipoprotein	ADJ
iajs-310	44	25	and	and	CCONJ
iajs-310	44	26	low	low	ADJ
iajs-310	44	27	density	density	NOUN
iajs-310	44	28	lipoprotein),insulin	lipoprotein),insulin	X
iajs-310	44	29	like	like	ADP
iajs-310	44	30	growth	growth	NOUN
iajs-310	44	31	factor	factor	NOUN
iajs-310	44	32	-1	-1	NOUN
iajs-310	44	33	determination	determination	NOUN
iajs-310	44	34	by	by	ADP
iajs-310	44	35	(	(	PUNCT
iajs-310	44	36	ria	ria	PROPN
iajs-310	44	37	)	)	PUNCT
iajs-310	44	38	kit	kit	NOUN
iajs-310	44	39	(	(	PUNCT
iajs-310	44	40	immunotech	immunotech	PROPN
iajs-310	44	41	)	)	PUNCT
iajs-310	44	42	,	,	PUNCT
iajs-310	44	43	leptin	leptin	NOUN
iajs-310	44	44	level	level	NOUN
iajs-310	44	45	determination	determination	NOUN
iajs-310	44	46	by	by	ADP
iajs-310	44	47	elise	elise	PROPN
iajs-310	44	48	kit	kit	PROPN
iajs-310	44	49	(	(	PUNCT
iajs-310	44	50	immunotech	immunotech	PROPN
iajs-310	44	51	)	)	PUNCT
iajs-310	44	52	and	and	CCONJ
iajs-310	44	53	atherogenic	atherogenic	ADJ
iajs-310	44	54	index	index	NOUN
iajs-310	44	55	of	of	ADP
iajs-310	44	56	plasma	plasma	NOUN
iajs-310	44	57	(	(	PUNCT
iajs-310	44	58	aip	aip	PROPN
iajs-310	44	59	)	)	PUNCT
iajs-310	44	60	calculated	calculate	VERB
iajs-310	44	61	by	by	ADP
iajs-310	44	62	464	464	NUM
iajs-310	44	63	|	|	ADV
iajs-310	44	64	chemistry	chemistry	NOUN
iajs-310	44	65	2014	2014	NUM
iajs-310	44	66	)	)	PUNCT
iajs-310	44	67	عام	عام	ADP
iajs-310	44	68	3(العدد	3(العدد	NUM
iajs-310	44	69	27المجلد	27المجلد	NUM
iajs-310	45	1	مجلة	مجلة	VERB
iajs-310	45	2	إبن	إبن	NOUN
iajs-310	45	3	الھيثم	الھيثم	NOUN
iajs-310	45	4	للعلوم	للعلوم	NOUN
iajs-310	45	5	الصرفة	الصرفة	NOUN
iajs-310	46	1	و	و	PRON
iajs-310	46	2	التطبيقية	التطبيقية	ADJ
iajs-310	46	3	ibn	ibn	PROPN
iajs-310	46	4	al	al	PROPN
iajs-310	46	5	-	-	PUNCT
iajs-310	46	6	haitham	haitham	PROPN
iajs-310	46	7	jour	jour	X
iajs-310	46	8	.	.	PROPN
iajs-310	46	9	for	for	ADP
iajs-310	46	10	pure	pure	ADJ
iajs-310	46	11	&	&	CCONJ
iajs-310	46	12	appl	appl	PROPN
iajs-310	46	13	.	.	PUNCT
iajs-310	47	1	sci	sci	PROPN
iajs-310	47	2	.	.	PUNCT
iajs-310	47	3	vol	vol	NOUN
iajs-310	47	4	.	.	PROPN
iajs-310	48	1	27	27	NUM
iajs-310	48	2	(	(	PUNCT
iajs-310	48	3	3	3	NUM
iajs-310	48	4	)	)	PUNCT
iajs-310	48	5	2014	2014	NUM
iajs-310	48	6	molar	molar	ADJ
iajs-310	48	7	ratio	ratio	NOUN
iajs-310	48	8	of	of	ADP
iajs-310	48	9	log(tg/	log(tg/	PROPN
iajs-310	48	10	hdl	hdl	PROPN
iajs-310	48	11	-	-	PUNCT
iajs-310	48	12	c	c	NOUN
iajs-310	48	13	)	)	PUNCT
iajs-310	48	14	.	.	PUNCT
iajs-310	49	1	data	datum	NOUN
iajs-310	49	2	processing	processing	NOUN
iajs-310	49	3	and	and	CCONJ
iajs-310	49	4	statistical	statistical	ADJ
iajs-310	49	5	analysis	analysis	NOUN
iajs-310	49	6	ware	ware	NOUN
iajs-310	49	7	done	do	VERB
iajs-310	49	8	by	by	ADP
iajs-310	49	9	the	the	DET
iajs-310	49	10	computer	computer	NOUN
iajs-310	49	11	spss15	spss15	NOUN
iajs-310	49	12	system	system	NOUN
iajs-310	49	13	(	(	PUNCT
iajs-310	49	14	statistical	statistical	ADJ
iajs-310	49	15	package	package	NOUN
iajs-310	49	16	for	for	ADP
iajs-310	49	17	social	social	ADJ
iajs-310	49	18	science	science	NOUN
iajs-310	49	19	–	–	PUNCT
iajs-310	49	20	version	version	NOUN
iajs-310	49	21	15	15	NUM
iajs-310	49	22	)	)	PUNCT
iajs-310	49	23	.	.	PUNCT
iajs-310	50	1	results	result	NOUN
iajs-310	50	2	and	and	CCONJ
iajs-310	50	3	discussion	discussion	NOUN
iajs-310	50	4	tables	table	NOUN
iajs-310	50	5	(	(	PUNCT
iajs-310	50	6	1,2,3	1,2,3	NOUN
iajs-310	50	7	)	)	PUNCT
iajs-310	50	8	revealed	reveal	VERB
iajs-310	50	9	the	the	DET
iajs-310	50	10	levels	level	NOUN
iajs-310	50	11	of	of	ADP
iajs-310	50	12	atherogenic	atherogenic	ADJ
iajs-310	50	13	index	index	NOUN
iajs-310	50	14	and	and	CCONJ
iajs-310	50	15	related	relate	VERB
iajs-310	50	16	clinical	clinical	ADJ
iajs-310	50	17	parameters	parameter	NOUN
iajs-310	50	18	investigated	investigate	VERB
iajs-310	50	19	throughout	throughout	ADP
iajs-310	50	20	the	the	DET
iajs-310	50	21	recent	recent	ADJ
iajs-310	50	22	study	study	NOUN
iajs-310	50	23	.	.	PUNCT
iajs-310	51	1	their	their	PRON
iajs-310	51	2	levels	level	NOUN
iajs-310	51	3	were	be	AUX
iajs-310	51	4	estimated	estimate	VERB
iajs-310	51	5	as	as	ADP
iajs-310	51	6	mean	mean	NOUN
iajs-310	51	7	±	±	NUM
iajs-310	51	8	sd	sd	NOUN
iajs-310	51	9	.	.	PUNCT
iajs-310	52	1	the	the	DET
iajs-310	52	2	result	result	NOUN
iajs-310	52	3	reflects	reflect	VERB
iajs-310	52	4	significant	significant	ADJ
iajs-310	52	5	elevation	elevation	NOUN
iajs-310	52	6	in	in	ADP
iajs-310	52	7	aip	aip	PROPN
iajs-310	52	8	(	(	PUNCT
iajs-310	52	9	p	p	X
iajs-310	52	10	<	<	X
iajs-310	52	11	0.05	0.05	NUM
iajs-310	52	12	)	)	PUNCT
iajs-310	52	13	in	in	ADP
iajs-310	52	14	all	all	DET
iajs-310	52	15	patient	patient	ADJ
iajs-310	52	16	groups	group	NOUN
iajs-310	52	17	compared	compare	VERB
iajs-310	52	18	with	with	ADP
iajs-310	52	19	that	that	PRON
iajs-310	52	20	of	of	ADP
iajs-310	52	21	control	control	NOUN
iajs-310	52	22	.	.	PUNCT
iajs-310	53	1	the	the	DET
iajs-310	53	2	result	result	NOUN
iajs-310	53	3	also	also	ADV
iajs-310	53	4	reflects	reflect	VERB
iajs-310	53	5	significant	significant	ADJ
iajs-310	53	6	elevation	elevation	NOUN
iajs-310	53	7	in	in	ADP
iajs-310	53	8	leptin	leptin	NOUN
iajs-310	53	9	(	(	PUNCT
iajs-310	53	10	p	p	X
iajs-310	53	11	<	<	X
iajs-310	53	12	0.05	0.05	NUM
iajs-310	53	13	)	)	PUNCT
iajs-310	53	14	compared	compare	VERB
iajs-310	53	15	with	with	ADP
iajs-310	53	16	that	that	PRON
iajs-310	53	17	of	of	ADP
iajs-310	53	18	control	control	NOUN
iajs-310	53	19	.	.	PUNCT
iajs-310	54	1	patient	patient	ADJ
iajs-310	54	2	groups	group	NOUN
iajs-310	54	3	suffer	suffer	VERB
iajs-310	54	4	from	from	ADP
iajs-310	54	5	t2	t2	PROPN
iajs-310	54	6	dm	dm	PROPN
iajs-310	54	7	as	as	SCONJ
iajs-310	54	8	confirmed	confirm	VERB
iajs-310	54	9	in	in	ADP
iajs-310	54	10	tables	table	NOUN
iajs-310	54	11	(	(	PUNCT
iajs-310	54	12	1,2	1,2	NUM
iajs-310	54	13	)	)	PUNCT
iajs-310	54	14	.	.	PUNCT
iajs-310	55	1	atherogenic	atherogenic	ADJ
iajs-310	55	2	index	index	NOUN
iajs-310	55	3	of	of	ADP
iajs-310	55	4	plasma	plasma	NOUN
iajs-310	55	5	(	(	PUNCT
iajs-310	55	6	aip	aip	PROPN
iajs-310	55	7	)	)	PUNCT
iajs-310	55	8	is	be	AUX
iajs-310	55	9	defined	define	VERB
iajs-310	55	10	as	as	ADP
iajs-310	55	11	log	log	NOUN
iajs-310	55	12	(	(	PUNCT
iajs-310	55	13	tg	tg	PROPN
iajs-310	55	14	/	/	SYM
iajs-310	55	15	hdl	hdl	PROPN
iajs-310	55	16	-	-	PUNCT
iajs-310	55	17	c	c	NOUN
iajs-310	55	18	)	)	PUNCT
iajs-310	55	19	,	,	PUNCT
iajs-310	55	20	has	have	AUX
iajs-310	55	21	been	be	AUX
iajs-310	55	22	proposed	propose	VERB
iajs-310	55	23	as	as	ADP
iajs-310	55	24	a	a	DET
iajs-310	55	25	marker	marker	NOUN
iajs-310	55	26	of	of	ADP
iajs-310	55	27	plasma	plasma	NOUN
iajs-310	55	28	atherogenicity	atherogenicity	NOUN
iajs-310	55	29	because	because	SCONJ
iajs-310	55	30	it	it	PRON
iajs-310	55	31	is	be	AUX
iajs-310	55	32	increased	increase	VERB
iajs-310	55	33	in	in	ADP
iajs-310	55	34	people	people	NOUN
iajs-310	55	35	at	at	ADP
iajs-310	55	36	higher	high	ADJ
iajs-310	55	37	risk	risk	NOUN
iajs-310	55	38	for	for	ADP
iajs-310	55	39	coronary	coronary	ADJ
iajs-310	55	40	heart	heart	NOUN
iajs-310	55	41	disease	disease	NOUN
iajs-310	55	42	and	and	CCONJ
iajs-310	55	43	is	be	AUX
iajs-310	55	44	correlated	correlate	VERB
iajs-310	55	45	with	with	ADP
iajs-310	55	46	ldl	ldl	NOUN
iajs-310	55	47	particle	particle	NOUN
iajs-310	55	48	size.[6	size.[6	PROPN
iajs-310	55	49	]	]	PUNCT
iajs-310	55	50	atherogenic	atherogenic	ADJ
iajs-310	55	51	index	index	NOUN
iajs-310	55	52	of	of	ADP
iajs-310	55	53	plasma(aip	plasma(aip	NOUN
iajs-310	55	54	)	)	PUNCT
iajs-310	55	55	provides	provide	VERB
iajs-310	55	56	prediction	prediction	NOUN
iajs-310	55	57	to	to	PART
iajs-310	55	58	accelerated	accelerated	VERB
iajs-310	55	59	development	development	NOUN
iajs-310	55	60	of	of	ADP
iajs-310	55	61	atherosclerosis	atherosclerosis	NOUN
iajs-310	55	62	in	in	ADP
iajs-310	55	63	diabetes	diabetes	NOUN
iajs-310	55	64	mellitus	mellitus	NOUN
iajs-310	55	65	patients.[4]osteoarthritis	patients.[4]osteoarthritis	CCONJ
iajs-310	55	66	(	(	PUNCT
iajs-310	55	67	oa	oa	X
iajs-310	55	68	)	)	PUNCT
iajs-310	55	69	is	be	AUX
iajs-310	55	70	a	a	DET
iajs-310	55	71	process	process	NOUN
iajs-310	55	72	of	of	ADP
iajs-310	55	73	progressive	progressive	ADJ
iajs-310	55	74	destruction	destruction	NOUN
iajs-310	55	75	of	of	ADP
iajs-310	55	76	articular	articular	ADJ
iajs-310	55	77	cartilage	cartilage	NOUN
iajs-310	55	78	which	which	PRON
iajs-310	55	79	makes	make	VERB
iajs-310	55	80	the	the	DET
iajs-310	55	81	oa	oa	PROPN
iajs-310	55	82	patients	patient	NOUN
iajs-310	55	83	physically	physically	ADV
iajs-310	55	84	inactive	inactive	ADJ
iajs-310	55	85	and	and	CCONJ
iajs-310	55	86	increases	increase	VERB
iajs-310	55	87	the	the	DET
iajs-310	55	88	probability	probability	NOUN
iajs-310	55	89	to	to	PART
iajs-310	55	90	develop	develop	VERB
iajs-310	55	91	(	(	PUNCT
iajs-310	55	92	cvd).[16	cvd).[16	PROPN
iajs-310	55	93	]	]	X
iajs-310	55	94	the	the	DET
iajs-310	55	95	probability	probability	NOUN
iajs-310	55	96	of	of	ADP
iajs-310	55	97	oa	oa	PROPN
iajs-310	55	98	patients	patient	NOUN
iajs-310	55	99	to	to	PART
iajs-310	55	100	develop	develop	VERB
iajs-310	55	101	future	future	ADJ
iajs-310	55	102	risk	risk	NOUN
iajs-310	55	103	of	of	ADP
iajs-310	55	104	cvd	cvd	PROPN
iajs-310	55	105	are	be	AUX
iajs-310	55	106	more	more	ADV
iajs-310	55	107	as	as	SCONJ
iajs-310	55	108	characterized	characterize	VERB
iajs-310	55	109	by	by	ADP
iajs-310	55	110	elevated	elevated	ADJ
iajs-310	55	111	antherogenic	antherogenic	ADJ
iajs-310	55	112	index	index	NOUN
iajs-310	55	113	,	,	PUNCT
iajs-310	55	114	systemic	systemic	ADJ
iajs-310	55	115	inflammation	inflammation	NOUN
iajs-310	55	116	and	and	CCONJ
iajs-310	55	117	oxidative	oxidative	ADJ
iajs-310	55	118	stress	stress	NOUN
iajs-310	55	119	and	and	CCONJ
iajs-310	55	120	reflect	reflect	VERB
iajs-310	55	121	the	the	DET
iajs-310	55	122	need	need	NOUN
iajs-310	55	123	of	of	ADP
iajs-310	55	124	antioxodants	antioxodant	NOUN
iajs-310	55	125	supplementation	supplementation	NOUN
iajs-310	55	126	along	along	ADP
iajs-310	55	127	with	with	ADP
iajs-310	55	128	drug	drug	NOUN
iajs-310	55	129	as	as	ADP
iajs-310	55	130	choice	choice	NOUN
iajs-310	55	131	to	to	PART
iajs-310	55	132	reduce	reduce	VERB
iajs-310	55	133	cvd	cvd	PROPN
iajs-310	55	134	risk	risk	NOUN
iajs-310	55	135	in	in	ADP
iajs-310	55	136	oa	oa	ADP
iajs-310	55	137	patients	patient	NOUN
iajs-310	55	138	.	.	PUNCT
iajs-310	56	1	[	[	X
iajs-310	56	2	17	17	NUM
iajs-310	56	3	]	]	PUNCT
iajs-310	56	4	although	although	SCONJ
iajs-310	56	5	precise	precise	ADJ
iajs-310	56	6	etiology	etiology	NOUN
iajs-310	56	7	of	of	ADP
iajs-310	56	8	this	this	DET
iajs-310	56	9	debilitating	debilitate	VERB
iajs-310	56	10	disease	disease	NOUN
iajs-310	56	11	(	(	PUNCT
iajs-310	56	12	oa	oa	INTJ
iajs-310	56	13	)	)	PUNCT
iajs-310	56	14	is	be	AUX
iajs-310	56	15	poorly	poorly	ADV
iajs-310	56	16	understood	understand	VERB
iajs-310	56	17	,	,	PUNCT
iajs-310	56	18	probability	probability	NOUN
iajs-310	56	19	of	of	ADP
iajs-310	56	20	oa	oa	PROPN
iajs-310	56	21	patient	patient	NOUN
iajs-310	56	22	to	to	PART
iajs-310	56	23	develop	develop	VERB
iajs-310	56	24	future	future	ADJ
iajs-310	56	25	cvd	cvd	PROPN
iajs-310	56	26	risk	risk	NOUN
iajs-310	56	27	is	be	AUX
iajs-310	56	28	more	more	ADV
iajs-310	56	29	due	due	ADJ
iajs-310	56	30	to	to	ADP
iajs-310	56	31	involvement	involvement	NOUN
iajs-310	56	32	of	of	ADP
iajs-310	56	33	some	some	DET
iajs-310	56	34	common	common	ADJ
iajs-310	56	35	cvd	cvd	PROPN
iajs-310	56	36	risk	risk	NOUN
iajs-310	56	37	factors	factor	NOUN
iajs-310	56	38	such	such	ADJ
iajs-310	56	39	as	as	ADP
iajs-310	56	40	high	high	ADJ
iajs-310	56	41	body	body	NOUN
iajs-310	56	42	mass	mass	NOUN
iajs-310	56	43	index	index	NOUN
iajs-310	56	44	,	,	PUNCT
iajs-310	56	45	aging	aging	NOUN
iajs-310	56	46	,	,	PUNCT
iajs-310	56	47	genetic	genetic	ADJ
iajs-310	56	48	factor	factor	NOUN
iajs-310	56	49	and	and	CCONJ
iajs-310	56	50	nutritional	nutritional	ADJ
iajs-310	56	51	factors	factor	NOUN
iajs-310	56	52	.	.	PUNCT
iajs-310	57	1	previous	previous	ADJ
iajs-310	57	2	studies	study	NOUN
iajs-310	57	3	have	have	AUX
iajs-310	57	4	also	also	ADV
iajs-310	57	5	shown	show	VERB
iajs-310	57	6	an	an	DET
iajs-310	57	7	excess	excess	NOUN
iajs-310	57	8	of	of	ADP
iajs-310	57	9	cardiovascular	cardiovascular	ADJ
iajs-310	57	10	risks	risk	NOUN
iajs-310	57	11	,	,	PUNCT
iajs-310	57	12	morbidity	morbidity	NOUN
iajs-310	57	13	and	and	CCONJ
iajs-310	57	14	mortality	mortality	NOUN
iajs-310	57	15	in	in	ADP
iajs-310	57	16	patients	patient	NOUN
iajs-310	57	17	with	with	ADP
iajs-310	57	18	arthritis	arthritis	NOUN
iajs-310	57	19	compared	compare	VERB
iajs-310	57	20	with	with	ADP
iajs-310	57	21	the	the	DET
iajs-310	57	22	general	general	ADJ
iajs-310	57	23	population[17,18	population[17,18	PROPN
iajs-310	57	24	]	]	PUNCT
iajs-310	57	25	.	.	PUNCT
iajs-310	58	1	in	in	ADP
iajs-310	58	2	type	type	NOUN
iajs-310	58	3	2	2	NUM
iajs-310	58	4	diabetes	diabetes	NOUN
iajs-310	58	5	,	,	PUNCT
iajs-310	58	6	insulin	insulin	NOUN
iajs-310	58	7	resistance	resistance	NOUN
iajs-310	58	8	and	and	CCONJ
iajs-310	58	9	obesity	obesity	NOUN
iajs-310	58	10	together	together	ADV
iajs-310	58	11	cause	cause	VERB
iajs-310	58	12	to	to	PART
iajs-310	58	13	moderate	moderate	ADJ
iajs-310	58	14	hypertriglyceridemia	hypertriglyceridemia	NOUN
iajs-310	58	15	and	and	CCONJ
iajs-310	58	16	also	also	ADV
iajs-310	58	17	cause	cause	VERB
iajs-310	58	18	reduction	reduction	NOUN
iajs-310	58	19	of	of	ADP
iajs-310	58	20	hdl	hdl	PROPN
iajs-310	58	21	-	-	PUNCT
iajs-310	58	22	c	c	PROPN
iajs-310	58	23	;	;	PUNCT
iajs-310	58	24	usually	usually	ADV
iajs-310	58	25	,	,	PUNCT
iajs-310	58	26	this	this	DET
iajs-310	58	27	dyslipidemia	dyslipidemia	NOUN
iajs-310	58	28	pattern	pattern	NOUN
iajs-310	58	29	is	be	AUX
iajs-310	58	30	involved	involve	VERB
iajs-310	58	31	with	with	ADP
iajs-310	58	32	excessive	excessive	ADJ
iajs-310	58	33	production	production	NOUN
iajs-310	58	34	of	of	ADP
iajs-310	58	35	very	very	ADV
iajs-310	58	36	low	low	ADJ
iajs-310	58	37	density	density	NOUN
iajs-310	58	38	lipoproteins	lipoprotein	NOUN
iajs-310	58	39	(	(	PUNCT
iajs-310	58	40	vldl	vldl	NOUN
iajs-310	58	41	)	)	PUNCT
iajs-310	58	42	.	.	PUNCT
iajs-310	59	1	excessive	excessive	ADJ
iajs-310	59	2	production	production	NOUN
iajs-310	59	3	of	of	ADP
iajs-310	59	4	tgrich	tgrich	NOUN
iajs-310	59	5	lipoprotein	lipoprotein	ADJ
iajs-310	59	6	.	.	PUNCT
iajs-310	60	1	tg	tg	PROPN
iajs-310	60	2	levels	level	NOUN
iajs-310	60	3	inversely	inversely	ADV
iajs-310	60	4	are	be	AUX
iajs-310	60	5	associated	associate	VERB
iajs-310	60	6	with	with	ADP
iajs-310	60	7	hdl	hdl	PROPN
iajs-310	60	8	-	-	PUNCT
iajs-310	60	9	c	c	PROPN
iajs-310	60	10	,	,	PUNCT
iajs-310	60	11	and	and	CCONJ
iajs-310	60	12	are	be	AUX
iajs-310	60	13	considered	consider	VERB
iajs-310	60	14	as	as	ADP
iajs-310	60	15	the	the	DET
iajs-310	60	16	carrier	carrier	NOUN
iajs-310	60	17	protein	protein	NOUN
iajs-310	60	18	for	for	ADP
iajs-310	60	19	cholesterol	cholesterol	NOUN
iajs-310	60	20	ester	ester	NOUN
iajs-310	60	21	in	in	ADP
iajs-310	60	22	transferring	transfer	VERB
iajs-310	60	23	cholesterol	cholesterol	NOUN
iajs-310	60	24	from	from	ADP
iajs-310	60	25	hdl	hdl	PROPN
iajs-310	60	26	-	-	PUNCT
iajs-310	60	27	c	c	NOUN
iajs-310	60	28	to	to	PART
iajs-310	60	29	vldl	vldl	VERB
iajs-310	60	30	.	.	PUNCT
iajs-310	61	1	some	some	DET
iajs-310	61	2	study	study	NOUN
iajs-310	61	3	showed	show	VERB
iajs-310	61	4	lipid	lipid	NOUN
iajs-310	61	5	profile	profile	NOUN
iajs-310	61	6	is	be	AUX
iajs-310	61	7	abnormal	abnormal	ADJ
iajs-310	61	8	,	,	PUNCT
iajs-310	61	9	and	and	CCONJ
iajs-310	61	10	is	be	AUX
iajs-310	61	11	characterized	characterize	VERB
iajs-310	61	12	by	by	ADP
iajs-310	61	13	modestly	modestly	ADV
iajs-310	61	14	elevated	elevate	VERB
iajs-310	61	15	ldl	ldl	NOUN
iajs-310	61	16	-	-	PUNCT
iajs-310	61	17	c	c	NOUN
iajs-310	61	18	,	,	PUNCT
iajs-310	61	19	high	high	ADJ
iajs-310	61	20	triglyceride	triglyceride	ADJ
iajs-310	61	21	levels	level	NOUN
iajs-310	61	22	,	,	PUNCT
iajs-310	61	23	and	and	CCONJ
iajs-310	61	24	is	be	AUX
iajs-310	61	25	associated	associate	VERB
iajs-310	61	26	with	with	ADP
iajs-310	61	27	markedly	markedly	ADV
iajs-310	61	28	increased	increase	VERB
iajs-310	61	29	cardiovascular	cardiovascular	ADJ
iajs-310	61	30	risk	risk	NOUN
iajs-310	61	31	among	among	ADP
iajs-310	61	32	diabetic	diabetic	ADJ
iajs-310	61	33	patients	patient	NOUN
iajs-310	61	34	.	.	PUNCT
iajs-310	62	1	[	[	X
iajs-310	62	2	19	19	NUM
iajs-310	62	3	]	]	X
iajs-310	62	4	leptin	leptin	NOUN
iajs-310	62	5	is	be	AUX
iajs-310	62	6	a	a	DET
iajs-310	62	7	16	16	NUM
iajs-310	62	8	kda	kda	NOUN
iajs-310	62	9	adipocyte	adipocyte	NOUN
iajs-310	62	10	-	-	PUNCT
iajs-310	62	11	derived	derive	VERB
iajs-310	62	12	hormone	hormone	NOUN
iajs-310	62	13	.	.	PUNCT
iajs-310	63	1	it	it	PRON
iajs-310	63	2	has	have	AUX
iajs-310	63	3	recently	recently	ADV
iajs-310	63	4	been	be	AUX
iajs-310	63	5	recognized	recognize	VERB
iajs-310	63	6	as	as	ADP
iajs-310	63	7	a	a	DET
iajs-310	63	8	modulator	modulator	NOUN
iajs-310	63	9	of	of	ADP
iajs-310	63	10	inflammatory	inflammatory	ADJ
iajs-310	63	11	and	and	CCONJ
iajs-310	63	12	immune	immune	ADJ
iajs-310	63	13	responses	response	NOUN
iajs-310	63	14	.	.	PUNCT
iajs-310	64	1	leptin	leptin	NOUN
iajs-310	64	2	has	have	VERB
iajs-310	64	3	a	a	DET
iajs-310	64	4	dual	dual	ADJ
iajs-310	64	5	role	role	NOUN
iajs-310	64	6	in	in	ADP
iajs-310	64	7	inflammation	inflammation	NOUN
iajs-310	64	8	.	.	PUNCT
iajs-310	65	1	[	[	X
iajs-310	65	2	20	20	NUM
iajs-310	65	3	]	]	X
iajs-310	65	4	it	it	PRON
iajs-310	65	5	is	be	AUX
iajs-310	65	6	a	a	DET
iajs-310	65	7	hormone	hormone	NOUN
iajs-310	65	8	produced	produce	VERB
iajs-310	65	9	by	by	ADP
iajs-310	65	10	adipose	adipose	ADJ
iajs-310	65	11	tissue	tissue	NOUN
iajs-310	65	12	,	,	PUNCT
iajs-310	65	13	acting	act	VERB
iajs-310	65	14	as	as	ADP
iajs-310	65	15	a	a	DET
iajs-310	65	16	sensor	sensor	NOUN
iajs-310	65	17	of	of	ADP
iajs-310	65	18	fat	fat	ADJ
iajs-310	65	19	mass	mass	NOUN
iajs-310	65	20	in	in	ADP
iajs-310	65	21	part	part	NOUN
iajs-310	65	22	of	of	ADP
iajs-310	65	23	a	a	DET
iajs-310	65	24	negative	negative	ADJ
iajs-310	65	25	feedback	feedback	NOUN
iajs-310	65	26	loop	loop	NOUN
iajs-310	65	27	that	that	PRON
iajs-310	65	28	maintains	maintain	VERB
iajs-310	65	29	a	a	DET
iajs-310	65	30	set	set	NOUN
iajs-310	65	31	point	point	NOUN
iajs-310	65	32	for	for	ADP
iajs-310	65	33	body	body	NOUN
iajs-310	65	34	fat	fat	NOUN
iajs-310	65	35	stores	store	NOUN
iajs-310	65	36	..	..	PUNCT
iajs-310	65	37	the	the	DET
iajs-310	65	38	role	role	NOUN
iajs-310	65	39	of	of	ADP
iajs-310	65	40	leptin	leptin	NOUN
iajs-310	65	41	in	in	ADP
iajs-310	65	42	the	the	DET
iajs-310	65	43	pathogenesis	pathogenesis	NOUN
iajs-310	65	44	of	of	ADP
iajs-310	65	45	oa	oa	PROPN
iajs-310	65	46	via	via	ADP
iajs-310	65	47	synthesis	synthesis	NOUN
iajs-310	65	48	of	of	ADP
iajs-310	65	49	igf1	igf1	PROPN
iajs-310	65	50	.	.	PUNCT
iajs-310	66	1	leptin	leptin	NOUN
iajs-310	66	2	over	over	ADP
iajs-310	66	3	expressed	express	VERB
iajs-310	66	4	transcription	transcription	NOUN
iajs-310	66	5	igf-1	igf-1	NOUN
iajs-310	66	6	.	.	PUNCT
iajs-310	66	7	leptin	leptin	VERB
iajs-310	66	8	either	either	CCONJ
iajs-310	66	9	alone	alone	ADJ
iajs-310	66	10	or	or	CCONJ
iajs-310	66	11	with	with	ADP
iajs-310	66	12	il-1	il-1	ADP
iajs-310	66	13	significantly	significantly	ADV
iajs-310	66	14	reduced	reduce	VERB
iajs-310	66	15	collagen	collagen	NOUN
iajs-310	66	16	release	release	NOUN
iajs-310	66	17	from	from	ADP
iajs-310	66	18	cartilage	cartilage	NOUN
iajs-310	66	19	by	by	ADP
iajs-310	66	20	up	up	ADP
iajs-310	66	21	regulating	regulate	VERB
iajs-310	66	22	colagenolytic	colagenolytic	ADJ
iajs-310	66	23	and	and	CCONJ
iajs-310	66	24	colagenolytic	colagenolytic	ADJ
iajs-310	66	25	activity	activity	NOUN
iajs-310	66	26	in	in	ADP
iajs-310	66	27	chondrocytes	chondrocyte	NOUN
iajs-310	66	28	,	,	PUNCT
iajs-310	66	29	and	and	CCONJ
iajs-310	66	30	acts	act	VERB
iajs-310	66	31	as	as	ADP
iajs-310	66	32	pro	pro	X
iajs-310	66	33	inflammatory	inflammatory	ADJ
iajs-310	66	34	adipokine	adipokine	NOUN
iajs-310	66	35	with	with	ADP
iajs-310	66	36	a	a	DET
iajs-310	66	37	catabolic	catabolic	ADJ
iajs-310	66	38	role	role	NOUN
iajs-310	66	39	on	on	ADP
iajs-310	66	40	cartilage	cartilage	NOUN
iajs-310	66	41	metabolism	metabolism	NOUN
iajs-310	66	42	via	via	ADP
iajs-310	66	43	the	the	DET
iajs-310	66	44	up	up	ADJ
iajs-310	66	45	regulation	regulation	NOUN
iajs-310	66	46	of	of	ADP
iajs-310	66	47	proteolysis	proteolysis	NOUN
iajs-310	66	48	enrages	enrage	VERB
iajs-310	66	49	.	.	PUNCT
iajs-310	67	1	this	this	PRON
iajs-310	67	2	suggests	suggest	VERB
iajs-310	67	3	that	that	SCONJ
iajs-310	67	4	fat	fat	ADJ
iajs-310	67	5	red	red	NOUN
iajs-310	67	6	in	in	ADP
iajs-310	67	7	arthritic	arthritic	ADJ
iajs-310	67	8	joints	joint	NOUN
iajs-310	67	9	is	be	AUX
iajs-310	67	10	local	local	ADJ
iajs-310	67	11	producer	producer	NOUN
iajs-310	67	12	of	of	ADP
iajs-310	67	13	leptin	leptin	NOUN
iajs-310	67	14	.	.	PUNCT
iajs-310	68	1	[	[	X
iajs-310	68	2	21	21	NUM
iajs-310	68	3	]	]	X
iajs-310	68	4	several	several	ADJ
iajs-310	68	5	studies	study	NOUN
iajs-310	68	6	have	have	AUX
iajs-310	68	7	demonstrated	demonstrate	VERB
iajs-310	68	8	the	the	DET
iajs-310	68	9	effects	effect	NOUN
iajs-310	68	10	of	of	ADP
iajs-310	68	11	leptin	leptin	NOUN
iajs-310	68	12	on	on	ADP
iajs-310	68	13	articular	articular	ADJ
iajs-310	68	14	cartilage	cartilage	NOUN
iajs-310	68	15	.[22,23	.[22,23	NOUN
iajs-310	68	16	]	]	PUNCT
iajs-310	68	17	and	and	CCONJ
iajs-310	68	18	its	its	PRON
iajs-310	68	19	role	role	NOUN
iajs-310	68	20	in	in	ADP
iajs-310	68	21	chondrocyte	chondrocyte	NOUN
iajs-310	68	22	function	function	NOUN
iajs-310	68	23	and	and	CCONJ
iajs-310	68	24	skeleton	skeleton	NOUN
iajs-310	68	25	,	,	PUNCT
iajs-310	68	26	as	as	ADV
iajs-310	68	27	well	well	ADV
iajs-310	68	28	as	as	ADP
iajs-310	68	29	in	in	ADP
iajs-310	68	30	inflammatory	inflammatory	ADJ
iajs-310	68	31	and	and	CCONJ
iajs-310	68	32	degenerative	degenerative	ADJ
iajs-310	68	33	cartilage	cartilage	NOUN
iajs-310	68	34	joint	joint	ADJ
iajs-310	68	35	diseases[24	diseases[24	NOUN
iajs-310	68	36	]	]	PUNCT
iajs-310	68	37	some	some	DET
iajs-310	68	38	studies	study	NOUN
iajs-310	68	39	have	have	AUX
iajs-310	68	40	shown	show	VERB
iajs-310	68	41	a	a	DET
iajs-310	68	42	role	role	NOUN
iajs-310	68	43	of	of	ADP
iajs-310	68	44	leptin	leptin	NOUN
iajs-310	68	45	as	as	ADP
iajs-310	68	46	pro	pro	ADJ
iajs-310	68	47	inflammatory	inflammatory	ADJ
iajs-310	68	48	mediators	mediator	NOUN
iajs-310	68	49	in	in	ADP
iajs-310	68	50	rheumatoid	rheumatoid	NOUN
iajs-310	68	51	arthritis	arthritis	NOUN
iajs-310	68	52	.	.	PUNCT
iajs-310	69	1	therefore	therefore	ADV
iajs-310	69	2	,	,	PUNCT
iajs-310	69	3	approaches	approach	NOUN
iajs-310	69	4	that	that	PRON
iajs-310	69	5	reduce	reduce	VERB
iajs-310	69	6	adipose	adipose	PRON
iajs-310	69	7	tissue	tissue	NOUN
iajs-310	69	8	depots	depot	NOUN
iajs-310	69	9	may	may	AUX
iajs-310	69	10	reduce	reduce	VERB
iajs-310	69	11	the	the	DET
iajs-310	69	12	severity	severity	NOUN
iajs-310	69	13	of	of	ADP
iajs-310	69	14	their	their	PRON
iajs-310	69	15	resultant	resultant	NOUN
iajs-310	69	16	pathologies.[25	pathologies.[25	PROPN
iajs-310	69	17	]	]	PUNCT
iajs-310	69	18	hormone	hormone	NOUN
iajs-310	69	19	that	that	PRON
iajs-310	69	20	has	have	AUX
iajs-310	69	21	been	be	AUX
iajs-310	69	22	shown	show	VERB
iajs-310	69	23	to	to	PART
iajs-310	69	24	be	be	AUX
iajs-310	69	25	involved	involve	VERB
iajs-310	69	26	in	in	ADP
iajs-310	69	27	pathways	pathway	NOUN
iajs-310	69	28	influencing	influence	VERB
iajs-310	69	29	the	the	DET
iajs-310	69	30	risk	risk	NOUN
iajs-310	69	31	of	of	ADP
iajs-310	69	32	diabetes	diabetes	NOUN
iajs-310	69	33	.	.	PUNCT
iajs-310	70	1	also	also	ADV
iajs-310	70	2	,	,	PUNCT
iajs-310	70	3	it	it	PRON
iajs-310	70	4	has	have	AUX
iajs-310	70	5	been	be	AUX
iajs-310	70	6	suggested	suggest	VERB
iajs-310	70	7	that	that	SCONJ
iajs-310	70	8	the	the	DET
iajs-310	70	9	association	association	NOUN
iajs-310	70	10	between	between	ADP
iajs-310	70	11	plasma	plasma	NOUN
iajs-310	70	12	leptin	leptin	NOUN
iajs-310	70	13	and	and	CCONJ
iajs-310	70	14	diabetes	diabetes	NOUN
iajs-310	70	15	may	may	AUX
iajs-310	70	16	be	be	AUX
iajs-310	70	17	a	a	DET
iajs-310	70	18	manifestation	manifestation	NOUN
iajs-310	70	19	of	of	ADP
iajs-310	70	20	an	an	DET
iajs-310	70	21	underlying	underlie	VERB
iajs-310	70	22	leptin	leptin	NOUN
iajs-310	70	23	resistance	resistance	NOUN
iajs-310	70	24	mediated	mediate	VERB
iajs-310	70	25	by	by	ADP
iajs-310	70	26	obesity.[26	obesity.[26	NOUN
iajs-310	70	27	]	]	PUNCT
iajs-310	70	28	igf-1	igf-1	PRON
iajs-310	70	29	shows	show	VERB
iajs-310	70	30	decreases	decrease	VERB
iajs-310	70	31	levels	level	NOUN
iajs-310	70	32	in	in	ADP
iajs-310	70	33	patient	patient	ADJ
iajs-310	70	34	groups	group	NOUN
iajs-310	70	35	when	when	SCONJ
iajs-310	70	36	compared	compare	VERB
iajs-310	70	37	with	with	ADP
iajs-310	70	38	control	control	NOUN
iajs-310	70	39	.the	.the	PUNCT
iajs-310	71	1	decreases	decrease	NOUN
iajs-310	71	2	were	be	AUX
iajs-310	71	3	shown	show	VERB
iajs-310	71	4	to	to	PART
iajs-310	71	5	be	be	AUX
iajs-310	71	6	significant	significant	ADJ
iajs-310	71	7	on	on	ADP
iajs-310	71	8	comparing	compare	VERB
iajs-310	71	9	igf-1	igf-1	NOUN
iajs-310	71	10	with	with	ADP
iajs-310	71	11	control	control	NOUN
iajs-310	71	12	.	.	PUNCT
iajs-310	72	1	insulin	insulin	NOUN
iajs-310	72	2	like	like	ADP
iajs-310	72	3	growth	growth	NOUN
iajs-310	72	4	factor-1	factor-1	PROPN
iajs-310	72	5	(	(	PUNCT
iajs-310	72	6	igf-1	igf-1	NOUN
iajs-310	72	7	)	)	PUNCT
iajs-310	72	8	is	be	AUX
iajs-310	72	9	a	a	DET
iajs-310	72	10	hormone	hormone	NOUN
iajs-310	72	11	similar	similar	ADJ
iajs-310	72	12	in	in	ADP
iajs-310	72	13	molecular	molecular	ADJ
iajs-310	72	14	structure	structure	NOUN
iajs-310	72	15	to	to	ADP
iajs-310	72	16	insulin	insulin	NOUN
iajs-310	72	17	.	.	PUNCT
iajs-310	73	1	it	it	PRON
iajs-310	73	2	plays	play	VERB
iajs-310	73	3	an	an	DET
iajs-310	73	4	important	important	ADJ
iajs-310	73	5	role	role	NOUN
iajs-310	73	6	in	in	ADP
iajs-310	73	7	465	465	NUM
iajs-310	74	1	|	|	ADV
iajs-310	74	2	chemistry	chemistry	NOUN
iajs-310	74	3	2014	2014	NUM
iajs-310	74	4	)	)	PUNCT
iajs-310	74	5	عام	عام	ADP
iajs-310	74	6	3(العدد	3(العدد	NUM
iajs-310	74	7	27المجلد	27المجلد	NUM
iajs-310	74	8	مجلة	مجلة	VERB
iajs-310	74	9	إبن	إبن	NOUN
iajs-310	74	10	الھيثم	الھيثم	NOUN
iajs-310	74	11	للعلوم	للعلوم	NOUN
iajs-310	74	12	الصرفة	الصرفة	NOUN
iajs-310	75	1	و	و	PRON
iajs-310	75	2	التطبيقية	التطبيقية	ADJ
iajs-310	75	3	ibn	ibn	PROPN
iajs-310	75	4	al	al	PROPN
iajs-310	75	5	-	-	PUNCT
iajs-310	75	6	haitham	haitham	PROPN
iajs-310	75	7	jour	jour	X
iajs-310	75	8	.	.	PROPN
iajs-310	75	9	for	for	ADP
iajs-310	75	10	pure	pure	ADJ
iajs-310	75	11	&	&	CCONJ
iajs-310	75	12	appl	appl	PROPN
iajs-310	75	13	.	.	PUNCT
iajs-310	76	1	sci	sci	PROPN
iajs-310	76	2	.	.	PUNCT
iajs-310	76	3	vol	vol	NOUN
iajs-310	76	4	.	.	PROPN
iajs-310	77	1	27	27	NUM
iajs-310	77	2	(	(	PUNCT
iajs-310	77	3	3	3	NUM
iajs-310	77	4	)	)	PUNCT
iajs-310	77	5	2014	2014	NUM
iajs-310	77	6	childhood	childhood	NOUN
iajs-310	77	7	growth	growth	NOUN
iajs-310	78	1	and	and	CCONJ
iajs-310	79	1	continues	continue	VERB
iajs-310	79	2	to	to	PART
iajs-310	79	3	have	have	VERB
iajs-310	79	4	anabolic	anabolic	NOUN
iajs-310	79	5	effects	effect	NOUN
iajs-310	79	6	in	in	ADP
iajs-310	79	7	adults	adult	NOUN
iajs-310	79	8	.	.	PUNCT
iajs-310	80	1	a	a	DET
iajs-310	80	2	synthetic	synthetic	ADJ
iajs-310	80	3	analog	analog	NOUN
iajs-310	80	4	of	of	ADP
iajs-310	80	5	igf1	igf1	PROPN
iajs-310	80	6	is	be	AUX
iajs-310	80	7	used	use	VERB
iajs-310	80	8	for	for	ADP
iajs-310	80	9	the	the	DET
iajs-310	80	10	treatment	treatment	NOUN
iajs-310	80	11	of	of	ADP
iajs-310	80	12	growth	growth	NOUN
iajs-310	80	13	failure.[27	failure.[27	PROPN
iajs-310	80	14	]	]	PUNCT
iajs-310	80	15	one	one	NUM
iajs-310	80	16	important	important	ADJ
iajs-310	80	17	key	key	NOUN
iajs-310	80	18	in	in	ADP
iajs-310	80	19	effectively	effectively	ADV
iajs-310	80	20	preventing	prevent	VERB
iajs-310	80	21	and	and	CCONJ
iajs-310	80	22	treating	treat	VERB
iajs-310	80	23	osteo	osteo	NOUN
iajs-310	80	24	arthritis	arthritis	NOUN
iajs-310	80	25	,	,	PUNCT
iajs-310	80	26	is	be	AUX
iajs-310	80	27	establishing	establish	VERB
iajs-310	80	28	a	a	DET
iajs-310	80	29	healthy	healthy	ADJ
iajs-310	80	30	balance	balance	NOUN
iajs-310	80	31	of	of	ADP
iajs-310	80	32	igf-1).[28	igf-1).[28	PROPN
iajs-310	80	33	]	]	PUNCT
iajs-310	80	34	(	(	PUNCT
iajs-310	80	35	igf-1	igf-1	NOUN
iajs-310	80	36	)	)	PUNCT
iajs-310	80	37	,	,	PUNCT
iajs-310	80	38	the	the	DET
iajs-310	80	39	most	most	ADV
iajs-310	80	40	abundant	abundant	ADJ
iajs-310	80	41	growth	growth	NOUN
iajs-310	80	42	factor	factor	NOUN
iajs-310	80	43	in	in	ADP
iajs-310	80	44	the	the	DET
iajs-310	80	45	bone	bone	NOUN
iajs-310	80	46	matrix	matrix	NOUN
iajs-310	80	47	,	,	PUNCT
iajs-310	80	48	regulates	regulate	VERB
iajs-310	80	49	bone	bone	NOUN
iajs-310	80	50	mass	mass	NOUN
iajs-310	80	51	in	in	ADP
iajs-310	80	52	adulthood.[29	adulthood.[29	PROPN
iajs-310	80	53	]	]	PUNCT
iajs-310	80	54	they	they	PRON
iajs-310	80	55	found	find	VERB
iajs-310	80	56	that	that	SCONJ
iajs-310	80	57	the	the	DET
iajs-310	80	58	level	level	NOUN
iajs-310	80	59	of	of	ADP
iajs-310	80	60	bone	bone	NOUN
iajs-310	80	61	marrow	marrow	NOUN
iajs-310	80	62	igf-1	igf-1	ADV
iajs-310	80	63	was	be	AUX
iajs-310	80	64	decreased	decrease	VERB
iajs-310	80	65	during	during	ADP
iajs-310	80	66	aging	age	VERB
iajs-310	80	67	in	in	ADP
iajs-310	80	68	rats	rat	NOUN
iajs-310	80	69	and	and	CCONJ
iajs-310	80	70	closely	closely	ADV
iajs-310	80	71	associated	associate	VERB
iajs-310	80	72	with	with	ADP
iajs-310	80	73	the	the	DET
iajs-310	80	74	bone	bone	NOUN
iajs-310	80	75	volume	volume	NOUN
iajs-310	80	76	whereas	whereas	SCONJ
iajs-310	80	77	serum	serum	NOUN
iajs-310	80	78	levels	level	NOUN
iajs-310	80	79	of	of	ADP
iajs-310	80	80	igf-1	igf-1	NOUN
iajs-310	80	81	were	be	AUX
iajs-310	80	82	relatively	relatively	ADV
iajs-310	80	83	steady[30	steady[30	X
iajs-310	80	84	]	]	X
iajs-310	81	1	it	it	PRON
iajs-310	81	2	was	be	AUX
iajs-310	81	3	postulated	postulate	VERB
iajs-310	81	4	that	that	SCONJ
iajs-310	81	5	a	a	DET
iajs-310	81	6	primary	primary	ADJ
iajs-310	81	7	function	function	NOUN
iajs-310	81	8	of	of	ADP
iajs-310	81	9	igf-1	igf-1	NOUN
iajs-310	81	10	in	in	ADP
iajs-310	81	11	the	the	DET
iajs-310	81	12	bone	bone	NOUN
iajs-310	81	13	matrix	matrix	NOUN
iajs-310	81	14	is	be	AUX
iajs-310	81	15	to	to	PART
iajs-310	81	16	maintain	maintain	VERB
iajs-310	81	17	bone	bone	NOUN
iajs-310	81	18	mass	mass	NOUN
iajs-310	81	19	and	and	CCONJ
iajs-310	81	20	skeletal	skeletal	ADJ
iajs-310	81	21	homeostasis	homeostasis	NOUN
iajs-310	81	22	during	during	ADP
iajs-310	81	23	bone	bone	NOUN
iajs-310	81	24	remodeling.[31	remodeling.[31	NOUN
iajs-310	81	25	]	]	PUNCT
iajs-310	81	26	igf-1	igf-1	PRON
iajs-310	81	27	has	have	AUX
iajs-310	81	28	been	be	AUX
iajs-310	81	29	shown	show	VERB
iajs-310	81	30	to	to	PART
iajs-310	81	31	enhance	enhance	VERB
iajs-310	81	32	chondrocyte	chondrocyte	NOUN
iajs-310	81	33	proliferation	proliferation	NOUN
iajs-310	81	34	,	,	PUNCT
iajs-310	81	35	proteoglycan	proteoglycan	ADJ
iajs-310	81	36	and	and	CCONJ
iajs-310	81	37	collagen	collagen	NOUN
iajs-310	81	38	synthesis	synthesis	NOUN
iajs-310	81	39	by	by	ADP
iajs-310	81	40	chondrocytes	chondrocyte	NOUN
iajs-310	81	41	in	in	ADP
iajs-310	81	42	normal	normal	ADJ
iajs-310	81	43	cartilage	cartilage	NOUN
iajs-310	81	44	,	,	PUNCT
iajs-310	81	45	both	both	PRON
iajs-310	81	46	in	in	ADP
iajs-310	81	47	vivo	vivo	ADJ
iajs-310	81	48	andin	andin	NOUN
iajs-310	81	49	vitro	vitro	X
iajs-310	82	1	[	[	X
iajs-310	82	2	32	32	NUM
iajs-310	82	3	]	]	PUNCT
iajs-310	82	4	also	also	ADV
iajs-310	82	5	during	during	ADP
iajs-310	82	6	cytokine	cytokine	ADJ
iajs-310	82	7	exposure	exposure	NOUN
iajs-310	82	8	,	,	PUNCT
iajs-310	82	9	which	which	PRON
iajs-310	82	10	drives	drive	VERB
iajs-310	82	11	most	most	ADV
iajs-310	82	12	predominating	predominate	VERB
iajs-310	82	13	catabolic	catabolic	ADJ
iajs-310	82	14	processes	process	NOUN
iajs-310	82	15	in	in	ADP
iajs-310	82	16	cartilage	cartilage	NOUN
iajs-310	82	17	.	.	PUNCT
iajs-310	83	1	furthermore	furthermore	ADV
iajs-310	83	2	,	,	PUNCT
iajs-310	83	3	igf-1	igf-1	PRON
iajs-310	83	4	inhibits	inhibit	VERB
iajs-310	83	5	cytokinestimulated	cytokinestimulate	VERB
iajs-310	83	6	degradation	degradation	NOUN
iajs-310	83	7	of	of	ADP
iajs-310	83	8	proteoglycans	proteoglycan	NOUN
iajs-310	83	9	directly	directly	ADV
iajs-310	83	10	in	in	ADP
iajs-310	83	11	normal	normal	ADJ
iajs-310	83	12	cartilage	cartilage	NOUN
iajs-310	83	13	in	in	ADP
iajs-310	83	14	vitro	vitro	X
iajs-310	83	15	.[33	.[33	PUNCT
iajs-310	83	16	]	]	PUNCT
iajs-310	83	17	association	association	NOUN
iajs-310	83	18	between	between	ADP
iajs-310	83	19	serum	serum	NOUN
iajs-310	83	20	igf-1	igf-1	NOUN
iajs-310	83	21	levels	level	NOUN
iajs-310	83	22	and	and	CCONJ
iajs-310	83	23	oa	oa	PROPN
iajs-310	83	24	is	be	AUX
iajs-310	83	25	very	very	ADV
iajs-310	83	26	important	important	ADJ
iajs-310	83	27	,	,	PUNCT
iajs-310	83	28	because	because	SCONJ
iajs-310	83	29	this	this	PRON
iajs-310	83	30	could	could	AUX
iajs-310	83	31	increase	increase	VERB
iajs-310	83	32	our	our	PRON
iajs-310	83	33	understanding	understanding	NOUN
iajs-310	83	34	of	of	ADP
iajs-310	83	35	the	the	DET
iajs-310	83	36	pathogenesis	pathogenesis	NOUN
iajs-310	83	37	of	of	ADP
iajs-310	83	38	oa	oa	NOUN
iajs-310	83	39	,	,	PUNCT
iajs-310	83	40	which	which	PRON
iajs-310	83	41	subsequently	subsequently	ADV
iajs-310	83	42	could	could	AUX
iajs-310	83	43	lead	lead	VERB
iajs-310	83	44	to	to	ADP
iajs-310	83	45	development	development	NOUN
iajs-310	83	46	of	of	ADP
iajs-310	83	47	new	new	ADJ
iajs-310	83	48	treatment	treatment	NOUN
iajs-310	83	49	options.[34	options.[34	PROPN
iajs-310	83	50	]	]	PUNCT
iajs-310	83	51	in	in	ADP
iajs-310	83	52	patients	patient	NOUN
iajs-310	83	53	with	with	ADP
iajs-310	83	54	type	type	NOUN
iajs-310	83	55	2	2	NUM
iajs-310	83	56	diabetes	diabetes	NOUN
iajs-310	83	57	,	,	PUNCT
iajs-310	83	58	serum	serum	NOUN
iajs-310	83	59	igf-1levels	igf-1level	NOUN
iajs-310	83	60	are	be	AUX
iajs-310	83	61	dependent	dependent	ADJ
iajs-310	83	62	on	on	ADP
iajs-310	83	63	the	the	DET
iajs-310	83	64	degree	degree	NOUN
iajs-310	83	65	of	of	ADP
iajs-310	83	66	metabolic	metabolic	NOUN
iajs-310	83	67	control	control	NOUN
iajs-310	83	68	,	,	PUNCT
iajs-310	83	69	with	with	ADP
iajs-310	83	70	near	near	ADP
iajs-310	83	71	normal	normal	ADJ
iajs-310	83	72	igf-1	igf-1	NOUN
iajs-310	83	73	levels	level	NOUN
iajs-310	83	74	in	in	ADP
iajs-310	83	75	wellcontrolled	wellcontrolle	VERB
iajs-310	83	76	diabetics	diabetic	NOUN
iajs-310	83	77	,	,	PUNCT
iajs-310	83	78	whereas	whereas	SCONJ
iajs-310	83	79	they	they	PRON
iajs-310	83	80	tend	tend	VERB
iajs-310	83	81	to	to	PART
iajs-310	83	82	be	be	AUX
iajs-310	83	83	decreased	decrease	VERB
iajs-310	83	84	in	in	ADP
iajs-310	83	85	poorly	poorly	ADV
iajs-310	83	86	controlled	control	VERB
iajs-310	83	87	diabetics	diabetic	NOUN
iajs-310	83	88	.	.	PUNCT
iajs-310	84	1	it	it	PRON
iajs-310	84	2	has	have	AUX
iajs-310	84	3	also	also	ADV
iajs-310	84	4	been	be	AUX
iajs-310	84	5	suggested	suggest	VERB
iajs-310	84	6	that	that	SCONJ
iajs-310	84	7	lowered	lower	VERB
iajs-310	84	8	serum	serum	NOUN
iajs-310	84	9	igf-1concentration	igf-1concentration	NOUN
iajs-310	84	10	predict	predict	VERB
iajs-310	84	11	worsening	worsen	VERB
iajs-310	84	12	of	of	ADP
iajs-310	84	13	insulin	insulin	NOUN
iajs-310	84	14	-	-	PUNCT
iajs-310	84	15	mediated	mediate	VERB
iajs-310	84	16	glucose	glucose	NOUN
iajs-310	84	17	uptake	uptake	NOUN
iajs-310	84	18	in	in	ADP
iajs-310	84	19	older	old	ADJ
iajs-310	84	20	people	people	NOUN
iajs-310	84	21	,	,	PUNCT
iajs-310	84	22	although	although	SCONJ
iajs-310	84	23	the	the	DET
iajs-310	84	24	mechanism	mechanism	NOUN
iajs-310	84	25	for	for	ADP
iajs-310	84	26	the	the	DET
iajs-310	84	27	progressive	progressive	ADJ
iajs-310	84	28	reduction	reduction	NOUN
iajs-310	84	29	of	of	ADP
iajs-310	84	30	circulating	circulate	VERB
iajs-310	84	31	serum	serum	NOUN
iajs-310	84	32	igf-1level	igf-1level	NOUN
iajs-310	84	33	with	with	ADP
iajs-310	84	34	ageing	age	VERB
iajs-310	84	35	in	in	ADP
iajs-310	84	36	patients	patient	NOUN
iajs-310	84	37	with	with	ADP
iajs-310	84	38	type	type	NOUN
iajs-310	84	39	2	2	NUM
iajs-310	84	40	diabetes	diabetes	NOUN
iajs-310	84	41	has	have	AUX
iajs-310	84	42	remained	remain	VERB
iajs-310	84	43	obscure	obscure	ADJ
iajs-310	84	44	,	,	PUNCT
iajs-310	84	45	it	it	PRON
iajs-310	84	46	has	have	AUX
iajs-310	84	47	been	be	AUX
iajs-310	84	48	suggested	suggest	VERB
iajs-310	84	49	that	that	SCONJ
iajs-310	84	50	this	this	DET
iajs-310	84	51	decreased	decrease	VERB
iajs-310	84	52	level	level	NOUN
iajs-310	84	53	is	be	AUX
iajs-310	84	54	at	at	ADP
iajs-310	84	55	least	least	ADJ
iajs-310	84	56	in	in	ADP
iajs-310	84	57	part	part	NOUN
iajs-310	84	58	a	a	DET
iajs-310	84	59	result	result	NOUN
iajs-310	84	60	of	of	ADP
iajs-310	84	61	decreased	decrease	VERB
iajs-310	84	62	igf-1	igf-1	NOUN
iajs-310	84	63	production	production	NOUN
iajs-310	84	64	through	through	ADP
iajs-310	84	65	lowered	lower	VERB
iajs-310	84	66	growth	growth	NOUN
iajs-310	84	67	hormone	hormone	NOUN
iajs-310	84	68	(	(	PUNCT
iajs-310	84	69	gh	gh	PROPN
iajs-310	84	70	)	)	PUNCT
iajs-310	84	71	concentration	concentration	NOUN
iajs-310	84	72	or	or	CCONJ
iajs-310	84	73	uncoupling	uncoupling	NOUN
iajs-310	84	74	of	of	ADP
iajs-310	84	75	the	the	DET
iajs-310	84	76	gh	gh	PROPN
iajs-310	84	77	induction	induction	NOUN
iajs-310	84	78	of	of	ADP
iajs-310	84	79	igf-1generation	igf-1generation	NOUN
iajs-310	84	80	by	by	ADP
iajs-310	84	81	insulin	insulin	NOUN
iajs-310	84	82	resistance	resistance	NOUN
iajs-310	84	83	.[35	.[35	NOUN
iajs-310	84	84	]	]	X
iajs-310	85	1	igf	igf	PROPN
iajs-310	85	2	-	-	PROPN
iajs-310	85	3	i	i	PRON
iajs-310	85	4	concentrations	concentration	NOUN
iajs-310	85	5	may	may	AUX
iajs-310	85	6	be	be	AUX
iajs-310	85	7	important	important	ADJ
iajs-310	85	8	in	in	ADP
iajs-310	85	9	the	the	DET
iajs-310	85	10	development	development	NOUN
iajs-310	85	11	of	of	ADP
iajs-310	85	12	osteoarthritis	osteoarthritis	PROPN
iajs-310	85	13	igf	igf	PROPN
iajs-310	85	14	-	-	ADJ
iajs-310	85	15	i	i	PROPN
iajs-310	85	16	receptors	receptor	NOUN
iajs-310	85	17	are	be	AUX
iajs-310	85	18	abundant	abundant	ADJ
iajs-310	85	19	in	in	ADP
iajs-310	85	20	bone	bone	NOUN
iajs-310	85	21	and	and	CCONJ
iajs-310	85	22	cartilage	cartilage	NOUN
iajs-310	85	23	,	,	PUNCT
iajs-310	85	24	and	and	CCONJ
iajs-310	85	25	in	in	ADP
iajs-310	85	26	vitro	vitro	X
iajs-310	85	27	work	work	NOUN
iajs-310	85	28	has	have	AUX
iajs-310	85	29	suggested	suggest	VERB
iajs-310	85	30	an	an	DET
iajs-310	85	31	anabolic	anabolic	ADJ
iajs-310	85	32	effect	effect	NOUN
iajs-310	85	33	of	of	ADP
iajs-310	85	34	igf	igf	PROPN
iajs-310	85	35	-	-	PROPN
iajs-310	85	36	i	i	PRON
iajs-310	85	37	on	on	ADP
iajs-310	85	38	chondrocytes	chondrocyte	NOUN
iajs-310	85	39	.	.	PUNCT
iajs-310	86	1	[	[	X
iajs-310	86	2	33	33	NUM
iajs-310	86	3	]	]	PUNCT
iajs-310	86	4	references	reference	NOUN
iajs-310	86	5	1terraciano	1terraciano	NUM
iajs-310	86	6	,	,	PUNCT
iajs-310	86	7	c.	c.	PROPN
iajs-310	86	8	;	;	PUNCT
iajs-310	86	9	celi	celi	PROPN
iajs-310	86	10	,	,	PUNCT
iajs-310	86	11	m.	m.	NOUN
iajs-310	86	12	;	;	PUNCT
iajs-310	86	13	lecce	lecce	PROPN
iajs-310	86	14	,	,	PUNCT
iajs-310	86	15	d.	d.	PROPN
iajs-310	86	16	;	;	PUNCT
iajs-310	86	17	baldi	baldi	PROPN
iajs-310	86	18	j.	j.	PROPN
iajs-310	86	19	;	;	PUNCT
iajs-310	86	20	restelli	restelli	PROPN
iajs-310	86	21	,	,	PUNCT
iajs-310	86	22	e.	e.	PROPN
iajs-310	86	23	;	;	PUNCT
iajs-310	86	24	massa	massa	PROPN
iajs-310	86	25	,	,	PUNCT
iajs-310	86	26	r.	r.	PROPN
iajs-310	86	27	;	;	PUNCT
iajs-310	86	28	and	and	CCONJ
iajs-310	86	29	tarantino	tarantino	PROPN
iajs-310	86	30	,	,	PUNCT
iajs-310	86	31	u.	u.	PROPN
iajs-310	86	32	(	(	PUNCT
iajs-310	86	33	2013	2013	NUM
iajs-310	86	34	)	)	PUNCT
iajs-310	86	35	“	"	PUNCT
iajs-310	86	36	differential	differential	ADJ
iajs-310	86	37	features	feature	NOUN
iajs-310	86	38	of	of	ADP
iajs-310	86	39	muscle	muscle	NOUN
iajs-310	86	40	fiber	fiber	NOUN
iajs-310	86	41	atrophy	atrophy	NOUN
iajs-310	86	42	in	in	ADP
iajs-310	86	43	osteoporosis	osteoporosis	NOUN
iajs-310	86	44	and	and	CCONJ
iajs-310	86	45	osteoarthritis	osteoarthritis	NOUN
iajs-310	86	46	”	"	PUNCT
iajs-310	86	47	,	,	PUNCT
iajs-310	86	48	osteoporas	osteopora	NOUN
iajs-310	86	49	int	int	VERB
iajs-310	86	50	.	.	PUNCT
iajs-310	86	51	,	,	PUNCT
iajs-310	86	52	24	24	NUM
iajs-310	86	53	:	:	PUNCT
iajs-310	86	54	1095	1095	NUM
iajs-310	86	55	-	-	SYM
iajs-310	86	56	1110	1110	NUM
iajs-310	86	57	.	.	PUNCT
iajs-310	87	1	2	2	NUM
iajs-310	87	2	-	-	PUNCT
iajs-310	87	3	leaverton	leaverton	NOUN
iajs-310	87	4	,	,	PUNCT
iajs-310	87	5	pe.;peregoy	pe.;peregoy	NOUN
iajs-310	87	6	,	,	PUNCT
iajs-310	87	7	j.	j.	PROPN
iajs-310	87	8	;	;	PUNCT
iajs-310	87	9	fahlman	fahlman	NOUN
iajs-310	87	10	,	,	PUNCT
iajs-310	87	11	l.	l.	PROPN
iajs-310	87	12	;	;	PUNCT
iajs-310	87	13	sangeorzan	sangeorzan	NOUN
iajs-310	87	14	,	,	PUNCT
iajs-310	87	15	e	e	PROPN
iajs-310	87	16	and	and	CCONJ
iajs-310	87	17	barrett	barrett	PROPN
iajs-310	87	18	,	,	PUNCT
iajs-310	87	19	jp	jp	PROPN
iajs-310	87	20	.	.	PUNCT
iajs-310	88	1	(	(	PUNCT
iajs-310	88	2	2012	2012	NUM
iajs-310	88	3	)	)	PUNCT
iajs-310	88	4	“	"	PUNCT
iajs-310	88	5	does	do	AUX
iajs-310	88	6	diabetes	diabetes	NOUN
iajs-310	88	7	hide	hide	VERB
iajs-310	88	8	osteoarthritis	osteoarthritis	NOUN
iajs-310	88	9	pain	pain	NOUN
iajs-310	88	10	?	?	PUNCT
iajs-310	88	11	”	"	PUNCT
iajs-310	88	12	,	,	PUNCT
iajs-310	88	13	medical	medical	ADJ
iajs-310	88	14	hypothesis	hypothesis	NOUN
iajs-310	88	15	(	(	PUNCT
iajs-310	88	16	in	in	ADP
iajs-310	88	17	press	press	NOUN
iajs-310	88	18	)	)	PUNCT
iajs-310	88	19	,	,	PUNCT
iajs-310	88	20	www.elsevir.com	www.elsevir.com	PRON
iajs-310	88	21	/locate	/locate	PROPN
iajs-310	88	22	/	/	SYM
iajs-310	88	23	mehy	mehy	ADJ
iajs-310	88	24	.	.	PUNCT
iajs-310	89	1	3	3	NUM
iajs-310	89	2	-	-	PUNCT
iajs-310	89	3	gomez	gomez	PROPN
iajs-310	89	4	,	,	PUNCT
iajs-310	89	5	r.	r.	PROPN
iajs-310	89	6	;	;	PUNCT
iajs-310	89	7	lago	lago	PROPN
iajs-310	89	8	,	,	PUNCT
iajs-310	89	9	f.	f.	PROPN
iajs-310	89	10	;	;	PUNCT
iajs-310	89	11	gomez	gomez	PROPN
iajs-310	89	12	-	-	PUNCT
iajs-310	89	13	rieno	rieno	PROPN
iajs-310	89	14	,	,	PUNCT
iajs-310	89	15	j.	j.	PROPN
iajs-310	89	16	;	;	PUNCT
iajs-310	89	17	dieguez	dieguez	NOUN
iajs-310	89	18	,	,	PUNCT
iajs-310	89	19	c	c	PROPN
iajs-310	89	20	and	and	CCONJ
iajs-310	89	21	guallillo	guallillo	PROPN
iajs-310	89	22	,	,	PUNCT
iajs-310	89	23	o.	o.	PROPN
iajs-310	89	24	(	(	PUNCT
iajs-310	89	25	2009	2009	NUM
iajs-310	89	26	)	)	PUNCT
iajs-310	89	27	“	"	PUNCT
iajs-310	89	28	adipokines	adipokine	NOUN
iajs-310	89	29	in	in	ADP
iajs-310	89	30	the	the	DET
iajs-310	89	31	skeleton	skeleton	NOUN
iajs-310	89	32	:	:	PUNCT
iajs-310	89	33	influence	influence	NOUN
iajs-310	89	34	on	on	ADP
iajs-310	89	35	cartilage	cartilage	NOUN
iajs-310	89	36	function	function	NOUN
iajs-310	89	37	and	and	CCONJ
iajs-310	89	38	joint	joint	ADJ
iajs-310	89	39	degenerative	degenerative	ADJ
iajs-310	89	40	diseases	disease	NOUN
iajs-310	89	41	”	"	PUNCT
iajs-310	89	42	,	,	PUNCT
iajs-310	89	43	j.	j.	PROPN
iajs-310	89	44	molecular	molecular	ADJ
iajs-310	89	45	endocrinol	endocrinol	NOUN
iajs-310	89	46	.	.	PUNCT
iajs-310	90	1	43	43	NUM
iajs-310	90	2	:	:	PUNCT
iajs-310	91	1	11	11	NUM
iajs-310	91	2	-	-	SYM
iajs-310	91	3	18	18	NUM
iajs-310	91	4	.	.	NOUN
iajs-310	92	1	4	4	NUM
iajs-310	92	2	-	-	NUM
iajs-310	92	3	rajpathak	rajpathak	NOUN
iajs-310	92	4	,	,	PUNCT
iajs-310	92	5	sn	sn	PROPN
iajs-310	92	6	.	.	PUNCT
iajs-310	92	7	;	;	PUNCT
iajs-310	93	1	gunter	gunter	NOUN
iajs-310	93	2	,	,	PUNCT
iajs-310	93	3	mj	mj	PROPN
iajs-310	93	4	.	.	PROPN
iajs-310	93	5	;	;	PUNCT
iajs-310	93	6	and	and	CCONJ
iajs-310	93	7	wylie	wylie	PROPN
iajs-310	93	8	-	-	PUNCT
iajs-310	93	9	rosett	rosett	NOUN
iajs-310	93	10	,	,	PUNCT
iajs-310	93	11	j.	j.	PROPN
iajs-310	93	12	;	;	PUNCT
iajs-310	93	13	(	(	PUNCT
iajs-310	93	14	2009	2009	NUM
iajs-310	93	15	)	)	PUNCT
iajs-310	93	16	"	"	PUNCT
iajs-310	93	17	the	the	DET
iajs-310	93	18	role	role	NOUN
iajs-310	93	19	of	of	ADP
iajs-310	93	20	insulin	insulin	NOUN
iajs-310	93	21	-	-	PUNCT
iajs-310	93	22	like	like	ADJ
iajs-310	93	23	growth	growth	NOUN
iajs-310	93	24	factor	factor	NOUN
iajs-310	93	25	-	-	PUNCT
iajs-310	93	26	i	i	PROPN
iajs-310	93	27	and	and	CCONJ
iajs-310	93	28	its	its	PRON
iajs-310	93	29	binding	bind	VERB
iajs-310	93	30	proteins	protein	NOUN
iajs-310	93	31	in	in	ADP
iajs-310	93	32	glucose	glucose	NOUN
iajs-310	93	33	homeostasis	homeostasis	NOUN
iajs-310	93	34	and	and	CCONJ
iajs-310	93	35	type	type	NOUN
iajs-310	93	36	2	2	NUM
iajs-310	93	37	diabetes	diabetes	NOUN
iajs-310	93	38	"	"	PUNCT
iajs-310	93	39	.	.	PUNCT
iajs-310	94	1	diabetes	diabete	VERB
iajs-310	94	2	metab	metab	NOUN
iajs-310	94	3	res	re	NOUN
iajs-310	94	4	rev	rev	X
iajs-310	94	5	;	;	PUNCT
iajs-310	94	6	25:3	25:3	NUM
iajs-310	94	7	.	.	X
iajs-310	95	1	5soska	5soska	NUM
iajs-310	95	2	,	,	PUNCT
iajs-310	95	3	v.	v.	ADV
iajs-310	95	4	;	;	PUNCT
iajs-310	95	5	jarkovsk	jarkovsk	NOUN
iajs-310	95	6	,	,	PUNCT
iajs-310	95	7	j.	j.	PROPN
iajs-310	95	8	;	;	PUNCT
iajs-310	95	9	ravcukova	ravcukova	PROPN
iajs-310	95	10	,	,	PUNCT
iajs-310	95	11	b.	b.	PROPN
iajs-310	95	12	;	;	PUNCT
iajs-310	95	13	tichy	tichy	PROPN
iajs-310	95	14	,	,	PUNCT
iajs-310	95	15	l.	l.	PROPN
iajs-310	95	16	;	;	PUNCT
iajs-310	95	17	fajkusova	fajkusova	PROPN
iajs-310	95	18	,	,	PUNCT
iajs-310	95	19	l	l	NOUN
iajs-310	95	20	,	,	PUNCT
iajs-310	95	21	;	;	PUNCT
iajs-310	95	22	and	and	CCONJ
iajs-310	95	23	freiberger	freiberger	NOUN
iajs-310	95	24	,	,	PUNCT
iajs-310	95	25	t.	t.	PROPN
iajs-310	95	26	(	(	PUNCT
iajs-310	95	27	2012	2012	NUM
iajs-310	95	28	)	)	PUNCT
iajs-310	95	29	"	"	PUNCT
iajs-310	95	30	the	the	DET
iajs-310	95	31	logarithm	logarithm	NOUN
iajs-310	95	32	of	of	ADP
iajs-310	95	33	the	the	DET
iajs-310	95	34	triglyceride	triglyceride	PROPN
iajs-310	95	35	/	/	SYM
iajs-310	95	36	hdl	hdl	NOUN
iajs-310	95	37	-	-	PUNCT
iajs-310	95	38	cholesterol	cholesterol	NOUN
iajs-310	95	39	ratio	ratio	NOUN
iajs-310	95	40	is	be	AUX
iajs-310	95	41	related	relate	VERB
iajs-310	95	42	to	to	ADP
iajs-310	95	43	the	the	DET
iajs-310	95	44	history	history	NOUN
iajs-310	95	45	of	of	ADP
iajs-310	95	46	cardiovascular	cardiovascular	ADJ
iajs-310	95	47	disease	disease	NOUN
iajs-310	95	48	in	in	ADP
iajs-310	95	49	patients	patient	NOUN
iajs-310	95	50	with	with	ADP
iajs-310	95	51	familial	familial	ADJ
iajs-310	95	52	hypercholesterolemia	hypercholesterolemia	NOUN
iajs-310	95	53	"	"	PUNCT
iajs-310	95	54	.	.	PUNCT
iajs-310	96	1	journal	journal	PROPN
iajs-310	96	2	clinical	clinical	ADJ
iajs-310	96	3	biochemistry	biochemistry	NOUN
iajs-310	96	4	.	.	PUNCT
iajs-310	97	1	45:96	45:96	NUM
iajs-310	97	2	-	-	SYM
iajs-310	97	3	100	100	NUM
iajs-310	97	4	.	.	PUNCT
iajs-310	98	1	6tan	6tan	NUM
iajs-310	98	2	,	,	PUNCT
iajs-310	98	3	m.	m.	NOUN
iajs-310	98	4	;	;	PUNCT
iajs-310	98	5	jones	jones	PROPN
iajs-310	98	6	,	,	PUNCT
iajs-310	98	7	d.	d.	PROPN
iajs-310	98	8	;	;	PUNCT
iajs-310	98	9	and	and	CCONJ
iajs-310	98	10	glazer	glazer	PROPN
iajs-310	98	11	,	,	PUNCT
iajs-310	98	12	n	n	CCONJ
iajs-310	98	13	,	,	PUNCT
iajs-310	98	14	b.	b.	PROPN
iajs-310	98	15	;	;	PUNCT
iajs-310	98	16	(	(	PUNCT
iajs-310	98	17	2004	2004	NUM
iajs-310	98	18	)	)	PUNCT
iajs-310	98	19	"	"	PUNCT
iajs-310	98	20	pioglitazone	pioglitazone	NOUN
iajs-310	98	21	reduces	reduce	VERB
iajs-310	98	22	atherogenic	atherogenic	ADJ
iajs-310	98	23	index	index	NOUN
iajs-310	98	24	of	of	ADP
iajs-310	98	25	plasma	plasma	NOUN
iajs-310	98	26	in	in	ADP
iajs-310	98	27	patients	patient	NOUN
iajs-310	98	28	with	with	ADP
iajs-310	98	29	type	type	NOUN
iajs-310	98	30	2	2	NUM
iajs-310	98	31	diabetes	diabetes	NOUN
iajs-310	98	32	"	"	PUNCT
iajs-310	98	33	.	.	PUNCT
iajs-310	99	1	clin	clin	PROPN
iajs-310	99	2	chem.50(7	chem.50(7	PROPN
iajs-310	99	3	):	):	PUNCT
iajs-310	99	4	1184	1184	NUM
iajs-310	99	5	-	-	SYM
iajs-310	99	6	1188	1188	NUM
iajs-310	99	7	.	.	PUNCT
iajs-310	100	1	7nwagha	7nwagha	NUM
iajs-310	100	2	,	,	PUNCT
iajs-310	100	3	ui	ui	PROPN
iajs-310	100	4	.	.	PUNCT
iajs-310	100	5	;	;	PUNCT
iajs-310	100	6	ikekpeazu	ikekpeazu	NOUN
iajs-310	100	7	,	,	PUNCT
iajs-310	100	8	ej	ej	PROPN
iajs-310	100	9	.	.	PUNCT
iajs-310	100	10	;	;	PUNCT
iajs-310	100	11	ejezie	ejezie	X
iajs-310	100	12	,	,	PUNCT
iajs-310	100	13	fe	fe	X
iajs-310	100	14	.	.	PUNCT
iajs-310	100	15	;	;	PUNCT
iajs-310	100	16	neboh	neboh	PROPN
iajs-310	100	17	,	,	PUNCT
iajs-310	100	18	ee	ee	PROPN
iajs-310	100	19	.	.	PUNCT
iajs-310	100	20	;	;	PUNCT
iajs-310	100	21	and	and	CCONJ
iajs-310	100	22	maduka	maduka	NOUN
iajs-310	100	23	,	,	PUNCT
iajs-310	100	24	ic	ic	PROPN
iajs-310	100	25	.;(2010	.;(2010	PROPN
iajs-310	100	26	)	)	PUNCT
iajs-310	100	27	"	"	PUNCT
iajs-310	100	28	atherogenic	atherogenic	ADJ
iajs-310	100	29	index	index	NOUN
iajs-310	100	30	of	of	ADP
iajs-310	100	31	plasma	plasma	NOUN
iajs-310	100	32	as	as	ADP
iajs-310	100	33	useful	useful	ADJ
iajs-310	100	34	predictor	predictor	NOUN
iajs-310	100	35	of	of	ADP
iajs-310	100	36	cardiovascular	cardiovascular	ADJ
iajs-310	100	37	risk	risk	NOUN
iajs-310	100	38	among	among	ADP
iajs-310	100	39	postmenopausal	postmenopausal	ADJ
iajs-310	100	40	women	woman	NOUN
iajs-310	100	41	in	in	ADP
iajs-310	100	42	enugu	enugu	PROPN
iajs-310	100	43	"	"	PUNCT
iajs-310	100	44	.	.	PUNCT
iajs-310	101	1	nigeria	nigeria	PROPN
iajs-310	101	2	;	;	PUNCT
iajs-310	101	3	afr	afr	PROPN
iajs-310	101	4	health	health	PROPN
iajs-310	101	5	sci	sci	PROPN
iajs-310	101	6	.	.	PUNCT
iajs-310	102	1	sep	sep	PROPN
iajs-310	102	2	;	;	PUNCT
iajs-310	102	3	10(3	10(3	NUM
iajs-310	102	4	):	):	PUNCT
iajs-310	102	5	248–252	248–252	NUM
iajs-310	102	6	.	.	PUNCT
iajs-310	103	1	8-	8-	X
iajs-310	103	2	.	.	X
iajs-310	103	3	dealy	dealy	PROPN
iajs-310	103	4	,	,	PUNCT
iajs-310	103	5	cn	cn	PROPN
iajs-310	103	6	.	.	PROPN
iajs-310	103	7	;	;	PUNCT
iajs-310	103	8	(	(	PUNCT
iajs-310	103	9	2012	2012	NUM
iajs-310	103	10	)	)	PUNCT
iajs-310	103	11	"	"	PUNCT
iajs-310	103	12	chondrogenic	chondrogenic	ADJ
iajs-310	103	13	progenitors	progenitor	NOUN
iajs-310	103	14	for	for	ADP
iajs-310	103	15	cartilage	cartilage	NOUN
iajs-310	103	16	repair	repair	NOUN
iajs-310	103	17	and	and	CCONJ
iajs-310	103	18	osteoarthritis	osteoarthritis	NOUN
iajs-310	103	19	treatment	treatment	NOUN
iajs-310	103	20	"	"	PUNCT
iajs-310	103	21	.	.	PUNCT
iajs-310	104	1	rheumatol	rheumatol	PROPN
iajs-310	104	2	curr	curr	PROPN
iajs-310	104	3	res	res	PROPN
iajs-310	104	4	3:10	3:10	NUM
iajs-310	104	5	.	.	PUNCT
iajs-310	105	1	466	466	NUM
iajs-310	105	2	|	|	ADV
iajs-310	105	3	chemistry	chemistry	NOUN
iajs-310	105	4	2014	2014	NUM
iajs-310	105	5	)	)	PUNCT
iajs-310	105	6	عام	عام	ADP
iajs-310	105	7	3(العدد	3(العدد	NUM
iajs-310	105	8	27المجلد	27المجلد	NUM
iajs-310	105	9	مجلة	مجلة	VERB
iajs-310	105	10	إبن	إبن	NOUN
iajs-310	105	11	الھيثم	الھيثم	NOUN
iajs-310	105	12	للعلوم	للعلوم	NOUN
iajs-310	105	13	الصرفة	الصرفة	NOUN
iajs-310	106	1	و	و	PRON
iajs-310	106	2	التطبيقية	التطبيقية	ADJ
iajs-310	106	3	ibn	ibn	PROPN
iajs-310	106	4	al	al	PROPN
iajs-310	106	5	-	-	PUNCT
iajs-310	106	6	haitham	haitham	PROPN
iajs-310	106	7	jour	jour	X
iajs-310	106	8	.	.	PROPN
iajs-310	106	9	for	for	ADP
iajs-310	106	10	pure	pure	ADJ
iajs-310	106	11	&	&	CCONJ
iajs-310	106	12	appl	appl	PROPN
iajs-310	106	13	.	.	PUNCT
iajs-310	107	1	sci	sci	PROPN
iajs-310	107	2	.	.	PUNCT
iajs-310	107	3	vol	vol	NOUN
iajs-310	107	4	.	.	PROPN
iajs-310	108	1	27	27	NUM
iajs-310	108	2	(	(	PUNCT
iajs-310	108	3	3	3	NUM
iajs-310	108	4	)	)	PUNCT
iajs-310	108	5	2014	2014	NUM
iajs-310	108	6	9bellometti	9bellometti	NUM
iajs-310	108	7	,	,	PUNCT
iajs-310	108	8	s.	s.	PROPN
iajs-310	108	9	;	;	PUNCT
iajs-310	108	10	giannini	giannini	PROPN
iajs-310	108	11	,	,	PUNCT
iajs-310	108	12	s.	s.	PROPN
iajs-310	108	13	;	;	PUNCT
iajs-310	108	14	sartori	sartori	PROPN
iajs-310	108	15	,	,	PUNCT
iajs-310	108	16	l.	l.	PROPN
iajs-310	108	17	;	;	PUNCT
iajs-310	108	18	and	and	CCONJ
iajs-310	108	19	crepaldi	crepaldi	PROPN
iajs-310	108	20	,	,	PUNCT
iajs-310	108	21	g.	g.	PROPN
iajs-310	108	22	;	;	PUNCT
iajs-310	108	23	(	(	PUNCT
iajs-310	108	24	1997	1997	NUM
iajs-310	108	25	)	)	PUNCT
iajs-310	108	26	"	"	PUNCT
iajs-310	108	27	cytokine	cytokine	ADJ
iajs-310	108	28	levels	level	NOUN
iajs-310	108	29	in	in	ADP
iajs-310	108	30	osteo	osteo	NOUN
iajs-310	108	31	arthritis	arthritis	NOUN
iajs-310	108	32	patients	patient	NOUN
iajs-310	108	33	undergoing	undergo	VERB
iajs-310	108	34	mud	mud	NOUN
iajs-310	108	35	bath	bath	NOUN
iajs-310	108	36	therapy	therapy	NOUN
iajs-310	108	37	"	"	PUNCT
iajs-310	108	38	.	.	PUNCT
iajs-310	109	1	int	int	PROPN
iajs-310	110	1	j	j	PROPN
iajs-310	110	2	clin	clin	PROPN
iajs-310	110	3	pharmacol	pharmacol	PROPN
iajs-310	110	4	res;17(4):149	res;17(4):149	PROPN
iajs-310	110	5	-	-	PUNCT
iajs-310	110	6	53	53	NUM
iajs-310	110	7	.	.	PUNCT
iajs-310	111	1	10dana	10dana	NUM
iajs-310	111	2	,	,	PUNCT
iajs-310	111	3	m.	m.	NOUN
iajs-310	111	4	niedowicz	niedowicz	PROPN
iajs-310	111	5	and	and	CCONJ
iajs-310	111	6	david	david	PROPN
iajs-310	111	7	l.	l.	PROPN
iajs-310	111	8	daleke	daleke	PROPN
iajs-310	111	9	.	.	PUNCT
iajs-310	112	1	(	(	PUNCT
iajs-310	112	2	2005	2005	NUM
iajs-310	112	3	)	)	PUNCT
iajs-310	112	4	."the	."the	DET
iajs-310	112	5	role	role	NOUN
iajs-310	112	6	of	of	ADP
iajs-310	112	7	oxidative	oxidative	ADJ
iajs-310	112	8	stress	stress	NOUN
iajs-310	112	9	in	in	ADP
iajs-310	112	10	diabetic	diabetic	ADJ
iajs-310	112	11	complications	complication	NOUN
iajs-310	112	12	"	"	PUNCT
iajs-310	112	13	by	by	ADP
iajs-310	112	14	humana	humana	PROPN
iajs-310	112	15	press	press	PROPN
iajs-310	112	16	inc	inc	PROPN
iajs-310	112	17	.	.	PUNCT
iajs-310	113	1	5:43,289–330	5:43,289–330	NUM
iajs-310	113	2	11-	11-	PROPN
iajs-310	113	3	.	.	PROPN
iajs-310	113	4	avruch	avruch	PROPN
iajs-310	113	5	,	,	PUNCT
iajs-310	113	6	j.	j.	PROPN
iajs-310	113	7	;	;	PUNCT
iajs-310	113	8	(	(	PUNCT
iajs-310	113	9	2006	2006	NUM
iajs-310	113	10	)	)	PUNCT
iajs-310	113	11	.	.	PUNCT
iajs-310	113	12	"	"	PUNCT
iajs-310	114	1	insulin	insulin	NOUN
iajs-310	114	2	and	and	CCONJ
iajs-310	114	3	amino	amino	NOUN
iajs-310	114	4	-	-	PUNCT
iajs-310	114	5	acid	acid	NOUN
iajs-310	114	6	regulation	regulation	NOUN
iajs-310	114	7	of	of	ADP
iajs-310	114	8	mtor	mtor	NOUN
iajs-310	114	9	signalling	signal	VERB
iajs-310	114	10	and	and	CCONJ
iajs-310	114	11	kinase	kinase	NOUN
iajs-310	114	12	activity	activity	NOUN
iajs-310	114	13	through	through	ADP
iajs-310	114	14	the	the	DET
iajs-310	114	15	rheb	rheb	ADJ
iajs-310	114	16	gtpase	gtpase	NOUN
iajs-310	114	17	"	"	PUNCT
iajs-310	114	18	.	.	PUNCT
iajs-310	115	1	oncogene	oncogene	NOUN
iajs-310	115	2	25	25	NUM
iajs-310	115	3	:	:	PUNCT
iajs-310	115	4	6361–6372	6361–6372	NUM
iajs-310	115	5	.	.	PUNCT
iajs-310	115	6	12steppan	12steppan	NUM
iajs-310	115	7	,	,	PUNCT
iajs-310	115	8	cm	cm	NOUN
iajs-310	115	9	.	.	PUNCT
iajs-310	115	10	;	;	PUNCT
iajs-310	116	1	bailey	bailey	PROPN
iajs-310	116	2	,	,	PUNCT
iajs-310	116	3	st	st	PROPN
iajs-310	116	4	.	.	PROPN
iajs-310	116	5	;	;	PUNCT
iajs-310	116	6	bhat	bhat	PROPN
iajs-310	116	7	,	,	PUNCT
iajs-310	116	8	s.	s.	PROPN
iajs-310	116	9	;	;	PUNCT
iajs-310	116	10	brown	brown	ADJ
iajs-310	116	11	,	,	PUNCT
iajs-310	116	12	ej	ej	PROPN
iajs-310	116	13	.	.	PROPN
iajs-310	116	14	;	;	PUNCT
iajs-310	116	15	banerjee	banerjee	PROPN
iajs-310	116	16	,	,	PUNCT
iajs-310	116	17	rr	rr	PROPN
iajs-310	116	18	.	.	PROPN
iajs-310	116	19	;	;	PUNCT
iajs-310	116	20	wright	wright	PROPN
iajs-310	116	21	,	,	PUNCT
iajs-310	116	22	cm	cm	PROPN
iajs-310	116	23	.	.	PUNCT
iajs-310	116	24	;	;	PUNCT
iajs-310	116	25	patel	patel	PROPN
iajs-310	116	26	,	,	PUNCT
iajs-310	116	27	hr	hr	PROPN
iajs-310	116	28	.	.	PUNCT
iajs-310	116	29	;	;	PUNCT
iajs-310	116	30	ahima	ahima	PROPN
iajs-310	116	31	,	,	PUNCT
iajs-310	116	32	rs.;and	rs.;and	PROPN
iajs-310	116	33	lazar	lazar	PROPN
iajs-310	116	34	,	,	PUNCT
iajs-310	116	35	ma	ma	PROPN
iajs-310	116	36	.	.	PROPN
iajs-310	116	37	(	(	PUNCT
iajs-310	116	38	2001	2001	NUM
iajs-310	116	39	)	)	PUNCT
iajs-310	116	40	"	"	PUNCT
iajs-310	116	41	the	the	DET
iajs-310	116	42	hormone	hormone	NOUN
iajs-310	116	43	resistin	resistin	NOUN
iajs-310	116	44	links	link	VERB
iajs-310	116	45	obesity	obesity	NOUN
iajs-310	116	46	to	to	ADP
iajs-310	116	47	diabetes	diabetes	NOUN
iajs-310	116	48	.nature	.nature	NOUN
iajs-310	116	49	"	"	PUNCT
iajs-310	116	50	.	.	PUNCT
iajs-310	117	1	409:307	409:307	NOUN
iajs-310	117	2	-	-	PUNCT
iajs-310	117	3	312	312	NUM
iajs-310	117	4	.	.	NOUN
iajs-310	117	5	13	13	NUM
iajs-310	117	6	.	.	PUNCT
iajs-310	118	1	rajala	rajala	PROPN
iajs-310	118	2	,	,	PUNCT
iajs-310	118	3	mw.;lin	mw.;lin	PROPN
iajs-310	118	4	,	,	PUNCT
iajs-310	118	5	y.;ranalletta	y.;ranalletta	PROPN
iajs-310	118	6	,	,	PUNCT
iajs-310	118	7	m.	m.	NOUN
iajs-310	118	8	;	;	PUNCT
iajs-310	118	9	yang	yang	PROPN
iajs-310	118	10	,	,	PUNCT
iajs-310	118	11	xm.;qian	xm.;qian	PROPN
iajs-310	118	12	,	,	PUNCT
iajs-310	118	13	h.	h.	PROPN
iajs-310	118	14	;	;	PUNCT
iajs-310	118	15	gingerich	gingerich	PROPN
iajs-310	118	16	,	,	PUNCT
iajs-310	118	17	r.	r.	PROPN
iajs-310	118	18	;	;	PUNCT
iajs-310	118	19	barzilai	barzilai	PROPN
iajs-310	118	20	,	,	PUNCT
iajs-310	118	21	n.	n.	NOUN
iajs-310	118	22	;	;	PUNCT
iajs-310	118	23	and	and	CCONJ
iajs-310	118	24	scherer	scherer	PROPN
iajs-310	118	25	,	,	PUNCT
iajs-310	118	26	pe	pe	PROPN
iajs-310	118	27	.	.	PUNCT
iajs-310	119	1	(	(	PUNCT
iajs-310	119	2	2002	2002	NUM
iajs-310	119	3	)	)	PUNCT
iajs-310	119	4	"	"	PUNCT
iajs-310	119	5	cell	cell	NOUN
iajs-310	119	6	type	type	NOUN
iajs-310	119	7	-	-	PUNCT
iajs-310	119	8	specific	specific	ADJ
iajs-310	119	9	expression	expression	NOUN
iajs-310	119	10	and	and	CCONJ
iajs-310	119	11	coregulation	coregulation	NOUN
iajs-310	119	12	of	of	ADP
iajs-310	119	13	murine	murine	ADJ
iajs-310	119	14	resistin	resistin	NOUN
iajs-310	119	15	and	and	CCONJ
iajs-310	119	16	resistin	resistin	NOUN
iajs-310	119	17	-	-	PUNCT
iajs-310	119	18	like	like	ADJ
iajs-310	119	19	molecule	molecule	NOUN
iajs-310	119	20	-	-	PUNCT
iajs-310	119	21	alpha	alpha	NOUN
iajs-310	119	22	in	in	ADP
iajs-310	119	23	adipose	adipose	ADJ
iajs-310	119	24	tissue	tissue	NOUN
iajs-310	119	25	"	"	PUNCT
iajs-310	119	26	.	.	PUNCT
iajs-310	120	1	mol	mol	ADP
iajs-310	120	2	endocrinol	endocrinol	NOUN
iajs-310	120	3	,	,	PUNCT
iajs-310	120	4	16:1920	16:1920	NUM
iajs-310	120	5	-	-	SYM
iajs-310	120	6	1930	1930	NUM
iajs-310	120	7	14chen	14chen	PROPN
iajs-310	120	8	,	,	PUNCT
iajs-310	120	9	h.	h.	PROPN
iajs-310	120	10	;	;	PUNCT
iajs-310	120	11	charlat	charlat	ADJ
iajs-310	120	12	,	,	PUNCT
iajs-310	120	13	o.;tartaglia	o.;tartaglia	PROPN
iajs-310	120	14	,	,	PUNCT
iajs-310	120	15	la	la	PROPN
iajs-310	120	16	.	.	PUNCT
iajs-310	120	17	;	;	PUNCT
iajs-310	120	18	woolf	woolf	PROPN
iajs-310	120	19	,	,	PUNCT
iajs-310	120	20	ea	ea	PROPN
iajs-310	120	21	.	.	PUNCT
iajs-310	120	22	;	;	PUNCT
iajs-310	120	23	weng	weng	PROPN
iajs-310	120	24	,	,	PUNCT
iajs-310	120	25	x.	x.	PROPN
iajs-310	120	26	;	;	PUNCT
iajs-310	120	27	ellis	ellis	PROPN
iajs-310	120	28	,	,	PUNCT
iajs-310	120	29	sj	sj	PROPN
iajs-310	120	30	.	.	PROPN
iajs-310	120	31	;	;	PUNCT
iajs-310	121	1	lakey	lakey	PROPN
iajs-310	121	2	,	,	PUNCT
iajs-310	121	3	nd	nd	PRON
iajs-310	121	4	.	.	PROPN
iajs-310	121	5	;	;	PUNCT
iajs-310	121	6	culpepper	culpepper	NOUN
iajs-310	121	7	,	,	PUNCT
iajs-310	121	8	j.;moore	j.;moore	PROPN
iajs-310	121	9	,	,	PUNCT
iajs-310	121	10	kj	kj	PROPN
iajs-310	121	11	.	.	PUNCT
iajs-310	121	12	;	;	PUNCT
iajs-310	121	13	breitbart	breitbart	PROPN
iajs-310	121	14	,	,	PUNCT
iajs-310	121	15	re	re	PROPN
iajs-310	121	16	.	.	PUNCT
iajs-310	121	17	;	;	PUNCT
iajs-310	121	18	duyk	duyk	NOUN
iajs-310	121	19	,	,	PUNCT
iajs-310	121	20	gm.;tepper	gm.;tepper	NOUN
iajs-310	121	21	,	,	PUNCT
iajs-310	121	22	ri	ri	PROPN
iajs-310	121	23	.	.	PROPN
iajs-310	121	24	;	;	PUNCT
iajs-310	121	25	and	and	CCONJ
iajs-310	121	26	morgenstern	morgenstern	ADJ
iajs-310	121	27	,	,	PUNCT
iajs-310	121	28	jp	jp	NOUN
iajs-310	121	29	.	.	PUNCT
iajs-310	122	1	(	(	PUNCT
iajs-310	122	2	1996)"evidence	1996)"evidence	NOUN
iajs-310	122	3	that	that	SCONJ
iajs-310	122	4	the	the	DET
iajs-310	122	5	diabetes	diabetes	NOUN
iajs-310	122	6	gene	gene	NOUN
iajs-310	122	7	encodes	encode	VERB
iajs-310	122	8	the	the	DET
iajs-310	122	9	leptin	leptin	NOUN
iajs-310	122	10	receptor	receptor	NOUN
iajs-310	122	11	:	:	PUNCT
iajs-310	122	12	identification	identification	NOUN
iajs-310	122	13	of	of	ADP
iajs-310	122	14	a	a	DET
iajs-310	122	15	mutation	mutation	NOUN
iajs-310	122	16	in	in	ADP
iajs-310	122	17	the	the	DET
iajs-310	122	18	leptin	leptin	NOUN
iajs-310	122	19	receptor	receptor	NOUN
iajs-310	122	20	gene	gene	NOUN
iajs-310	122	21	in	in	ADP
iajs-310	122	22	db	db	PROPN
iajs-310	122	23	/	/	SYM
iajs-310	122	24	db	db	PROPN
iajs-310	122	25	mice	mouse	NOUN
iajs-310	122	26	"	"	PUNCT
iajs-310	122	27	.	.	PUNCT
iajs-310	123	1	cell	cell	NOUN
iajs-310	123	2	,	,	PUNCT
iajs-310	123	3	84:491	84:491	NUM
iajs-310	123	4	-	-	SYM
iajs-310	123	5	495	495	NUM
iajs-310	123	6	.	.	PUNCT
iajs-310	124	1	15bishop	15bishop	NUM
iajs-310	124	2	,	,	PUNCT
iajs-310	124	3	m.l	m.l	PROPN
iajs-310	124	4	.	.	PUNCT
iajs-310	124	5	;	;	PUNCT
iajs-310	124	6	fody	fody	NOUN
iajs-310	124	7	,	,	PUNCT
iajs-310	124	8	e.p.;and	e.p.;and	PROPN
iajs-310	124	9	schosff	schosff	NOUN
iajs-310	124	10	,	,	PUNCT
iajs-310	124	11	l.e	l.e	PROPN
iajs-310	124	12	.	.	PROPN
iajs-310	124	13	(	(	PUNCT
iajs-310	124	14	2010	2010	NUM
iajs-310	124	15	)	)	PUNCT
iajs-310	124	16	"	"	PUNCT
iajs-310	124	17	clinical	clinical	ADJ
iajs-310	124	18	chemistry	chemistry	NOUN
iajs-310	124	19	techniques	technique	NOUN
iajs-310	124	20	,	,	PUNCT
iajs-310	124	21	principles	principle	NOUN
iajs-310	124	22	,	,	PUNCT
iajs-310	124	23	correlations".6th	correlations".6th	ADP
iajs-310	124	24	ed	ed	NOUN
iajs-310	124	25	.	.	PUNCT
iajs-310	125	1	lippincott	lippincott	PROPN
iajs-310	125	2	williams	williams	PROPN
iajs-310	125	3	and	and	CCONJ
iajs-310	125	4	wilikins	wilikin	NOUN
iajs-310	125	5	:	:	PUNCT
iajs-310	125	6	wolter	wolter	PROPN
iajs-310	125	7	kulmer	kulmer	PROPN
iajs-310	125	8	heath	heath	PROPN
iajs-310	125	9	,	,	PUNCT
iajs-310	125	10	.	.	PUNCT
iajs-310	126	1	16rahul	16rahul	NUM
iajs-310	127	1	sexana	sexana	PROPN
iajs-310	127	2	.	.	PUNCT
iajs-310	127	3	;	;	PUNCT
iajs-310	127	4	ijen	ijen	PROPN
iajs-310	127	5	bhattacharya.;and	bhattacharya.;and	PROPN
iajs-310	127	6	raj	raj	PROPN
iajs-310	127	7	sexana	sexana	PROPN
iajs-310	127	8	.	.	PUNCT
iajs-310	128	1	(	(	PUNCT
iajs-310	128	2	2013)"susceptibility	2013)"susceptibility	NUM
iajs-310	128	3	of	of	ADP
iajs-310	128	4	knee	knee	NOUN
iajs-310	128	5	osteoarthritis	osteoarthritis	NOUN
iajs-310	128	6	patients	patient	NOUN
iajs-310	128	7	to	to	PART
iajs-310	128	8	develop	develop	VERB
iajs-310	128	9	cardiovascular	cardiovascular	ADJ
iajs-310	128	10	disease	disease	NOUN
iajs-310	128	11	"	"	PUNCT
iajs-310	128	12	-a	-a	PUNCT
iajs-310	128	13	clinical	clinical	ADJ
iajs-310	128	14	study	study	NOUN
iajs-310	128	15	asian	asian	PROPN
iajs-310	128	16	journal	journal	PROPN
iajs-310	128	17	of	of	ADP
iajs-310	128	18	medical	medical	ADJ
iajs-310	128	19	sciences	science	NOUN
iajs-310	128	20	,	,	PUNCT
iajs-310	128	21	4	4	NUM
iajs-310	128	22	:	:	SYM
iajs-310	128	23	3	3	NUM
iajs-310	128	24	.	.	NOUN
iajs-310	128	25	17	17	NUM
iajs-310	128	26	-	-	PUNCT
iajs-310	128	27	sanghi	sanghi	PROPN
iajs-310	128	28	,	,	PUNCT
iajs-310	128	29	d.	d.	PROPN
iajs-310	128	30	;	;	PUNCT
iajs-310	128	31	avasthi	avasthi	ADV
iajs-310	128	32	,	,	PUNCT
iajs-310	128	33	s.	s.	PROPN
iajs-310	128	34	;	;	PUNCT
iajs-310	128	35	srivastava	srivastava	PROPN
iajs-310	128	36	,	,	PUNCT
iajs-310	128	37	rn	rn	PROPN
iajs-310	128	38	.	.	PROPN
iajs-310	128	39	and	and	CCONJ
iajs-310	128	40	singh	singh	PROPN
iajs-310	128	41	a.	a.	NOUN
iajs-310	128	42	(	(	PUNCT
iajs-310	128	43	2009	2009	NUM
iajs-310	128	44	)	)	PUNCT
iajs-310	128	45	"	"	PUNCT
iajs-310	128	46	nutritional	nutritional	ADJ
iajs-310	128	47	factors	factor	NOUN
iajs-310	128	48	and	and	CCONJ
iajs-310	128	49	osteoarthritis".a	osteoarthritis".a	ADP
iajs-310	128	50	review	review	NOUN
iajs-310	128	51	article	article	NOUN
iajs-310	128	52	.	.	PUNCT
iajs-310	129	1	int	int	PROPN
iajs-310	129	2	j	j	PROPN
iajs-310	129	3	med	med	ADJ
iajs-310	129	4	update	update	NOUN
iajs-310	129	5	,	,	PUNCT
iajs-310	129	6	4(1	4(1	NOUN
iajs-310	129	7	):	):	PUNCT
iajs-310	129	8	42	42	NUM
iajs-310	129	9	-	-	SYM
iajs-310	129	10	53	53	NUM
iajs-310	129	11	.	.	PUNCT
iajs-310	130	1	18watson	18watson	NUM
iajs-310	130	2	,	,	PUNCT
iajs-310	130	3	dj	dj	PROPN
iajs-310	130	4	.	.	PROPN
iajs-310	130	5	;	;	PUNCT
iajs-310	130	6	rhodes	rhode	NOUN
iajs-310	130	7	,	,	PUNCT
iajs-310	130	8	t.	t.	NOUN
iajs-310	130	9	and	and	CCONJ
iajs-310	130	10	guess	guess	NOUN
iajs-310	130	11	,	,	PUNCT
iajs-310	130	12	ha	ha	INTJ
iajs-310	130	13	.	.	PUNCT
iajs-310	131	1	"	"	PUNCT
iajs-310	131	2	all	all	DET
iajs-310	131	3	-	-	PUNCT
iajs-310	131	4	cause	cause	NOUN
iajs-310	131	5	mortality	mortality	NOUN
iajs-310	131	6	and	and	CCONJ
iajs-310	131	7	vascular	vascular	ADJ
iajs-310	131	8	events	event	NOUN
iajs-310	131	9	among	among	ADP
iajs-310	131	10	patients	patient	NOUN
iajs-310	131	11	with	with	ADP
iajs-310	131	12	rheumatoid	rheumatoid	NOUN
iajs-310	131	13	arthritis	arthritis	NOUN
iajs-310	131	14	,	,	PUNCT
iajs-310	131	15	osteoarthritis	osteoarthritis	NOUN
iajs-310	131	16	,	,	PUNCT
iajs-310	131	17	or	or	CCONJ
iajs-310	131	18	no	no	DET
iajs-310	131	19	arthritis	arthritis	NOUN
iajs-310	131	20	in	in	ADP
iajs-310	131	21	the	the	DET
iajs-310	131	22	uk	uk	PROPN
iajs-310	131	23	general	general	ADJ
iajs-310	131	24	practice	practice	NOUN
iajs-310	131	25	research	research	NOUN
iajs-310	131	26	database	database	NOUN
iajs-310	131	27	"	"	PUNCT
iajs-310	131	28	.	.	PUNCT
iajs-310	132	1	j	j	PROPN
iajs-310	132	2	rheumatol	rheumatol	NOUN
iajs-310	132	3	(	(	PUNCT
iajs-310	132	4	2003	2003	NUM
iajs-310	132	5	)	)	PUNCT
iajs-310	132	6	,	,	PUNCT
iajs-310	132	7	30:1196	30:1196	PROPN
iajs-310	132	8	-	-	SYM
iajs-310	132	9	1202	1202	NUM
iajs-310	132	10	.	.	PUNCT
iajs-310	133	1	19	19	NUM
iajs-310	133	2	-	-	PUNCT
iajs-310	133	3	sadeghi	sadeghi	PROPN
iajs-310	133	4	m	m	VERB
iajs-310	133	5	.	.	PUNCT
iajs-310	133	6	;	;	PUNCT
iajs-310	134	1	roohafza	roohafza	PROPN
iajs-310	134	2	h	h	NOUN
iajs-310	134	3	.	.	PUNCT
iajs-310	134	4	;	;	PUNCT
iajs-310	134	5	shirani	shirani	PROPN
iajs-310	134	6	s	s	PART
iajs-310	134	7	.;and	.;and	PUNCT
iajs-310	134	8	poormoghadas	poormoghadas	PROPN
iajs-310	134	9	m.	m.	NOUN
iajs-310	134	10	;	;	PUNCT
iajs-310	134	11	.	.	PUNCT
iajs-310	134	12	2007	2007	NUM
iajs-310	135	1	"	"	PUNCT
iajs-310	135	2	diabetes	diabetes	NOUN
iajs-310	135	3	and	and	CCONJ
iajs-310	135	4	associated	associate	VERB
iajs-310	135	5	cardio	cardio	NOUN
iajs-310	135	6	vascular	vascular	ADJ
iajs-310	135	7	risk	risk	NOUN
iajs-310	135	8	factors	factor	NOUN
iajs-310	135	9	in	in	ADP
iajs-310	135	10	iran	iran	PROPN
iajs-310	135	11	"	"	PUNCT
iajs-310	135	12	.	.	PUNCT
iajs-310	136	1	the	the	DET
iajs-310	136	2	isfahan	isfahan	NOUN
iajs-310	136	3	healthy	healthy	ADJ
iajs-310	136	4	heart	heart	NOUN
iajs-310	136	5	programme	programme	NOUN
iajs-310	136	6	.	.	PUNCT
iajs-310	137	1	ann	ann	PROPN
iajs-310	137	2	acad	acad	PROPN
iajs-310	137	3	mad	mad	ADJ
iajs-310	137	4	singapore	singapore	PROPN
iajs-310	137	5	;	;	PUNCT
iajs-310	137	6	36:175	36:175	NUM
iajs-310	137	7	–	–	PUNCT
iajs-310	137	8	80	80	NUM
iajs-310	137	9	.	.	NOUN
iajs-310	138	1	20	20	NUM
iajs-310	138	2	—	—	PUNCT
iajs-310	138	3	otero	otero	NOUN
iajs-310	138	4	,	,	PUNCT
iajs-310	138	5	m.	m.	NOUN
iajs-310	138	6	;	;	PUNCT
iajs-310	138	7	lago	lago	PROPN
iajs-310	138	8	m.;gomez	m.;gomez	PROPN
iajs-310	138	9	,	,	PUNCT
iajs-310	138	10	r.	r.	PROPN
iajs-310	138	11	;	;	PUNCT
iajs-310	138	12	lago	lago	PROPN
iajs-310	138	13	f.	f.	PROPN
iajs-310	138	14	;	;	PUNCT
iajs-310	138	15	dieguez	dieguez	NOUN
iajs-310	138	16	,	,	PUNCT
iajs-310	138	17	c.;gomez	c.;gomez	NOUN
iajs-310	138	18	-	-	PUNCT
iajs-310	138	19	reino	reino	NOUN
iajs-310	138	20	,	,	PUNCT
iajs-310	138	21	j.	j.	PROPN
iajs-310	138	22	and	and	CCONJ
iajs-310	138	23	gualillo	gualillo	PROPN
iajs-310	138	24	,	,	PUNCT
iajs-310	138	25	o.	o.	PROPN
iajs-310	138	26	(	(	PUNCT
iajs-310	138	27	2006	2006	NUM
iajs-310	138	28	)	)	PUNCT
iajs-310	138	29	"	"	PUNCT
iajs-310	138	30	changes	change	NOUN
iajs-310	138	31	in	in	ADP
iajs-310	138	32	plasma	plasma	NOUN
iajs-310	138	33	levels	level	NOUN
iajs-310	138	34	of	of	ADP
iajs-310	138	35	fat	fat	ADJ
iajs-310	138	36	-	-	PUNCT
iajs-310	138	37	derived	derive	VERB
iajs-310	138	38	hormones	hormone	NOUN
iajs-310	138	39	adiponectin	adiponectin	NOUN
iajs-310	138	40	,	,	PUNCT
iajs-310	138	41	leptin	leptin	NOUN
iajs-310	138	42	,	,	PUNCT
iajs-310	138	43	resistin	resistin	NOUN
iajs-310	138	44	and	and	CCONJ
iajs-310	138	45	visfatin	visfatin	NOUN
iajs-310	138	46	in	in	ADP
iajs-310	138	47	patients	patient	NOUN
iajs-310	138	48	with	with	ADP
iajs-310	138	49	rheumatoid	rheumatoid	NOUN
iajs-310	138	50	arthritis	arthritis	NOUN
iajs-310	138	51	"	"	PUNCT
iajs-310	138	52	.	.	PUNCT
iajs-310	139	1	ann	ann	PROPN
iajs-310	139	2	.	.	PUNCT
iajs-310	139	3	rheum	rheum	PROPN
iajs-310	139	4	dis	dis	PROPN
iajs-310	139	5	.	.	PUNCT
iajs-310	139	6	;	;	PUNCT
iajs-310	139	7	65	65	NUM
iajs-310	139	8	(	(	PUNCT
iajs-310	139	9	9	9	NUM
iajs-310	139	10	):	):	PUNCT
iajs-310	139	11	1198	1198	NUM
iajs-310	139	12	-	-	SYM
iajs-310	139	13	201	201	NUM
iajs-310	139	14	.	.	PUNCT
iajs-310	140	1	21	21	NUM
iajs-310	140	2	-	-	PUNCT
iajs-310	140	3	wang	wang	PROPN
iajs-310	140	4	,	,	PUNCT
iajs-310	140	5	hui	hui	PROPN
iajs-310	140	6	.	.	PROPN
iajs-310	140	7	;	;	PUNCT
iajs-310	140	8	gary	gary	PROPN
iajs-310	140	9	,	,	PUNCT
iajs-310	140	10	j	j	PROPN
iajs-310	140	11	litherl	litherl	NOUN
iajs-310	140	12	and	and	CCONJ
iajs-310	140	13	.	.	PUNCT
iajs-310	140	14	;	;	PUNCT
iajs-310	140	15	and	and	CCONJ
iajs-310	140	16	martina	martina	PROPN
iajs-310	140	17	,	,	PUNCT
iajs-310	140	18	s	s	PART
iajs-310	140	19	elias	elias	PROPN
iajs-310	140	20	.	.	PUNCT
iajs-310	140	21	;	;	PUNCT
iajs-310	141	1	(	(	PUNCT
iajs-310	141	2	2012	2012	NUM
iajs-310	141	3	)	)	PUNCT
iajs-310	141	4	"	"	PUNCT
iajs-310	141	5	leptin	leptin	NOUN
iajs-310	141	6	produced	produce	VERB
iajs-310	141	7	by	by	ADP
iajs-310	141	8	joint	joint	ADJ
iajs-310	141	9	white	white	ADJ
iajs-310	141	10	adipose	adipose	ADP
iajs-310	141	11	tissue	tissue	NOUN
iajs-310	141	12	induces	induce	VERB
iajs-310	141	13	cartilage	cartilage	NOUN
iajs-310	141	14	degradation	degradation	NOUN
iajs-310	141	15	via	via	ADP
iajs-310	141	16	upregulation	upregulation	NOUN
iajs-310	141	17	and	and	CCONJ
iajs-310	141	18	activation	activation	NOUN
iajs-310	141	19	of	of	ADP
iajs-310	141	20	matrix	matrix	NOUN
iajs-310	141	21	metalloproteinases	metalloproteinase	NOUN
iajs-310	141	22	"	"	PUNCT
iajs-310	141	23	.	.	PUNCT
iajs-310	142	1	ann	ann	PROPN
iajs-310	142	2	rheum	rheum	PROPN
iajs-310	142	3	dis	dis	PROPN
iajs-310	142	4	;	;	PUNCT
iajs-310	143	1	71:3	71:3	NUM
iajs-310	143	2	455	455	NUM
iajs-310	143	3	-	-	SYM
iajs-310	143	4	462	462	NUM
iajs-310	143	5	.	.	PUNCT
iajs-310	143	6	22	22	NUM
iajs-310	143	7	.	.	PUNCT
iajs-310	144	1	gandhi	gandhi	PROPN
iajs-310	144	2	,	,	PUNCT
iajs-310	144	3	r.	r.	PROPN
iajs-310	144	4	;	;	PUNCT
iajs-310	144	5	takahashi	takahashi	PROPN
iajs-310	144	6	,	,	PUNCT
iajs-310	144	7	m.	m.	NOUN
iajs-310	144	8	;	;	PUNCT
iajs-310	144	9	syed	syed	ADJ
iajs-310	144	10	,	,	PUNCT
iajs-310	144	11	k.	k.	PROPN
iajs-310	144	12	;	;	PUNCT
iajs-310	144	13	davey	davey	PROPN
iajs-310	144	14	,	,	PUNCT
iajs-310	144	15	jr	jr	PROPN
iajs-310	144	16	.	.	PROPN
iajs-310	144	17	;	;	PUNCT
iajs-310	144	18	and	and	CCONJ
iajs-310	144	19	mahomed	mahome	VERB
iajs-310	144	20	,	,	PUNCT
iajs-310	144	21	nn	nn	PROPN
iajs-310	144	22	.	.	PROPN
iajs-310	144	23	(	(	PUNCT
iajs-310	144	24	2010	2010	NUM
iajs-310	144	25	)	)	PUNCT
iajs-310	144	26	"	"	PUNCT
iajs-310	144	27	relationship	relationship	NOUN
iajs-310	144	28	between	between	ADP
iajs-310	144	29	body	body	NOUN
iajs-310	144	30	habitus	habitus	NOUN
iajs-310	144	31	and	and	CCONJ
iajs-310	144	32	joint	joint	ADJ
iajs-310	144	33	leptin	leptin	NOUN
iajs-310	144	34	levelsin	levelsin	NOUN
iajs-310	144	35	a	a	DET
iajs-310	144	36	knee	knee	NOUN
iajs-310	144	37	osteoarthritis	osteoarthritis	NOUN
iajs-310	144	38	population	population	NOUN
iajs-310	144	39	"	"	PUNCT
iajs-310	144	40	.	.	PUNCT
iajs-310	145	1	j	j	PROPN
iajs-310	145	2	orthop	orthop	PROPN
iajs-310	145	3	res	re	NOUN
iajs-310	145	4	.	.	PUNCT
iajs-310	145	5	;	;	PUNCT
iajs-310	146	1	28(3):329–33	28(3):329–33	NUM
iajs-310	146	2	.	.	PUNCT
iajs-310	147	1	23presle	23presle	NUM
iajs-310	147	2	,	,	PUNCT
iajs-310	147	3	n.	n.	NOUN
iajs-310	147	4	;	;	PUNCT
iajs-310	147	5	pottie	pottie	NOUN
iajs-310	147	6	,	,	PUNCT
iajs-310	147	7	p.	p.	NOUN
iajs-310	147	8	;	;	PUNCT
iajs-310	148	1	dumond	dumond	PROPN
iajs-310	148	2	,	,	PUNCT
iajs-310	148	3	h.	h.	PROPN
iajs-310	148	4	;	;	PUNCT
iajs-310	148	5	guillaume	guillaume	PROPN
iajs-310	148	6	,	,	PUNCT
iajs-310	148	7	c.	c.	PROPN
iajs-310	148	8	;	;	PUNCT
iajs-310	148	9	lapicque	lapicque	NOUN
iajs-310	148	10	,	,	PUNCT
iajs-310	148	11	f.	f.	PROPN
iajs-310	148	12	;	;	PUNCT
iajs-310	148	13	pallu	pallu	NOUN
iajs-310	148	14	,	,	PUNCT
iajs-310	148	15	s.	s.	PROPN
iajs-310	148	16	;	;	PUNCT
iajs-310	148	17	mainard	mainard	PROPN
iajs-310	148	18	,	,	PUNCT
iajs-310	148	19	d.	d.	PROPN
iajs-310	148	20	;	;	PUNCT
iajs-310	148	21	netter	netter	PROPN
iajs-310	148	22	p.	p.	PROPN
iajs-310	148	23	;	;	PUNCT
iajs-310	148	24	terlain	terlain	PROPN
iajs-310	148	25	,	,	PUNCT
iajs-310	148	26	b.	b.	PROPN
iajs-310	148	27	(	(	PUNCT
iajs-310	148	28	2006	2006	NUM
iajs-310	148	29	)	)	PUNCT
iajs-310	148	30	"	"	PUNCT
iajs-310	148	31	differential	differential	ADJ
iajs-310	148	32	distribution	distribution	NOUN
iajs-310	148	33	of	of	ADP
iajs-310	148	34	adipokines	adipokine	NOUN
iajs-310	148	35	between	between	ADP
iajs-310	148	36	serum	serum	NOUN
iajs-310	148	37	and	and	CCONJ
iajs-310	148	38	synovial	synovial	ADJ
iajs-310	148	39	fluid	fluid	NOUN
iajs-310	148	40	in	in	ADP
iajs-310	148	41	patients	patient	NOUN
iajs-310	148	42	with	with	ADP
iajs-310	148	43	osteoarthritis	osteoarthritis	NOUN
iajs-310	148	44	"	"	PUNCT
iajs-310	148	45	.	.	PUNCT
iajs-310	149	1	contribution	contribution	NOUN
iajs-310	149	2	of	of	ADP
iajs-310	149	3	joint	joint	ADJ
iajs-310	149	4	tissues	tissue	NOUN
iajs-310	149	5	to	to	ADP
iajs-310	149	6	their	their	PRON
iajs-310	149	7	articular	articular	ADJ
iajs-310	149	8	production	production	NOUN
iajs-310	149	9	.	.	PUNCT
iajs-310	150	1	osteoarthritis	osteoarthritis	PROPN
iajs-310	150	2	cartilage.;14(7):690–95	cartilage.;14(7):690–95	PROPN
iajs-310	150	3	.	.	PUNCT
iajs-310	151	1	24rodolfo	24rodolfo	PROPN
iajs-310	151	2	gomez	gomez	PROPN
iajs-310	151	3	.	.	PUNCT
iajs-310	151	4	;	;	PUNCT
iajs-310	151	5	francisca	francisca	PROPN
iajs-310	151	6	lago	lago	PROPN
iajs-310	151	7	.	.	PUNCT
iajs-310	151	8	;	;	PUNCT
iajs-310	151	9	juan	juan	PROPN
iajs-310	151	10	gomez	gomez	PROPN
iajs-310	151	11	-	-	PUNCT
iajs-310	151	12	reino	reino	PROPN
iajs-310	151	13	.	.	PUNCT
iajs-310	151	14	;	;	PUNCT
iajs-310	151	15	carlos	carlos	PROPN
iajs-310	151	16	dieguez	dieguez	PROPN
iajs-310	151	17	and	and	CCONJ
iajs-310	151	18	oreste	oreste	VERB
iajs-310	151	19	gualillo	gualillo	PROPN
iajs-310	151	20	.	.	PUNCT
iajs-310	152	1	(	(	PUNCT
iajs-310	152	2	2009	2009	NUM
iajs-310	152	3	)	)	PUNCT
iajs-310	152	4	"	"	PUNCT
iajs-310	152	5	adipokines	adipokine	NOUN
iajs-310	152	6	in	in	ADP
iajs-310	152	7	the	the	DET
iajs-310	152	8	skeleton	skeleton	NOUN
iajs-310	152	9	:	:	PUNCT
iajs-310	152	10	influence	influence	NOUN
iajs-310	152	11	on	on	ADP
iajs-310	152	12	cartilage	cartilage	NOUN
iajs-310	152	13	function	function	NOUN
iajs-310	152	14	and	and	CCONJ
iajs-310	152	15	joint	joint	ADJ
iajs-310	152	16	degenerative	degenerative	ADJ
iajs-310	152	17	diseases	disease	NOUN
iajs-310	152	18	"	"	PUNCT
iajs-310	152	19	.	.	PUNCT
iajs-310	153	1	journal	journal	NOUN
iajs-310	153	2	of	of	ADP
iajs-310	153	3	molecular	molecular	ADJ
iajs-310	153	4	endocrinology	endocrinology	NOUN
iajs-310	153	5	43	43	NUM
iajs-310	153	6	,	,	PUNCT
iajs-310	153	7	11–18	11–18	NUM
iajs-310	153	8	.	.	NOUN
iajs-310	153	9	25	25	NUM
iajs-310	153	10	-	-	PUNCT
iajs-310	153	11	manal	manal	ADJ
iajs-310	153	12	,	,	PUNCT
iajs-310	153	13	m.	m.	NOUN
iajs-310	153	14	;	;	PUNCT
iajs-310	153	15	el	el	NOUN
iajs-310	153	16	-	-	PUNCT
iajs-310	153	17	batch	batch	NOUN
iajs-310	153	18	.	.	PUNCT
iajs-310	153	19	;	;	PUNCT
iajs-310	154	1	soha	soha	PROPN
iajs-310	154	2	,	,	PUNCT
iajs-310	154	3	s	s	VERB
iajs-310	154	4	zakaria	zakaria	PROPN
iajs-310	154	5	.	.	PUNCT
iajs-310	154	6	;	;	PUNCT
iajs-310	154	7	gihan	gihan	PROPN
iajs-310	154	8	farouk.;hanan	farouk.;hanan	PROPN
iajs-310	154	9	,	,	PUNCT
iajs-310	154	10	el	el	PROPN
iajs-310	154	11	saadany	saadany	PROPN
iajs-310	154	12	.	.	PUNCT
iajs-310	154	13	;	;	PUNCT
iajs-310	154	14	and	and	CCONJ
iajs-310	154	15	mahmoud	mahmoud	PROPN
iajs-310	154	16	selim.(2010)"changes	selim.(2010)"change	NOUN
iajs-310	154	17	in	in	ADP
iajs-310	154	18	visfatin	visfatin	NOUN
iajs-310	154	19	,	,	PUNCT
iajs-310	154	20	adiponectin	adiponectin	NOUN
iajs-310	154	21	,	,	PUNCT
iajs-310	154	22	leptin	leptin	NOUN
iajs-310	154	23	and	and	CCONJ
iajs-310	154	24	ghrelin	ghrelin	NOUN
iajs-310	154	25	levels	level	NOUN
iajs-310	154	26	in	in	ADP
iajs-310	154	27	patients	patient	NOUN
iajs-310	154	28	with	with	ADP
iajs-310	154	29	rheumatoid	rheumatoid	NOUN
iajs-310	154	30	arthritis	arthritis	NOUN
iajs-310	154	31	and	and	CCONJ
iajs-310	154	32	their	their	PRON
iajs-310	154	33	correlation	correlation	NOUN
iajs-310	154	34	with	with	ADP
iajs-310	154	35	disease	disease	NOUN
iajs-310	154	36	activity	activity	NOUN
iajs-310	154	37	"	"	PUNCT
iajs-310	154	38	.	.	PUNCT
iajs-310	155	1	turkish	turkish	ADJ
iajs-310	155	2	journal	journal	PROPN
iajs-310	155	3	of	of	ADP
iajs-310	155	4	biochemistry	biochemistry	NOUN
iajs-310	155	5	;	;	PUNCT
iajs-310	155	6	35	35	NUM
iajs-310	155	7	(	(	PUNCT
iajs-310	155	8	1	1	NUM
iajs-310	155	9	)	)	PUNCT
iajs-310	155	10	;	;	PUNCT
iajs-310	156	1	50–57	50–57	NUM
iajs-310	156	2	.	.	PUNCT
iajs-310	157	1	26simopoulou	26simopoulou	NUM
iajs-310	157	2	,	,	PUNCT
iajs-310	157	3	t.	t.	PROPN
iajs-310	157	4	;	;	PUNCT
iajs-310	157	5	malizos	malizos	PROPN
iajs-310	157	6	,	,	PUNCT
iajs-310	157	7	kn	kn	PROPN
iajs-310	157	8	.	.	PROPN
iajs-310	157	9	;	;	PUNCT
iajs-310	157	10	iliopoulos	iliopoulos	PROPN
iajs-310	157	11	,	,	PUNCT
iajs-310	157	12	d.;stefanou	d.;stefanou	NOUN
iajs-310	157	13	,	,	PUNCT
iajs-310	157	14	n.	n.	NOUN
iajs-310	157	15	;	;	PUNCT
iajs-310	157	16	papatheodorou	papatheodorou	PROPN
iajs-310	157	17	,	,	PUNCT
iajs-310	157	18	l.;ioannou	l.;ioannou	NOUN
iajs-310	157	19	m.	m.	NOUN
iajs-310	157	20	;	;	PUNCT
iajs-310	157	21	and	and	CCONJ
iajs-310	157	22	tsezou	tsezou	NOUN
iajs-310	157	23	,	,	PUNCT
iajs-310	157	24	a.	a.	NOUN
iajs-310	157	25	(	(	PUNCT
iajs-310	157	26	2007	2007	NUM
iajs-310	157	27	)	)	PUNCT
iajs-310	157	28	.	.	PUNCT
iajs-310	158	1	"	"	PUNCT
iajs-310	158	2	differential	differential	ADJ
iajs-310	158	3	expression	expression	NOUN
iajs-310	158	4	of	of	ADP
iajs-310	158	5	leptin	leptin	NOUN
iajs-310	158	6	and	and	CCONJ
iajs-310	158	7	leptin	leptin	PROPN
iajs-310	158	8	’s	’s	PART
iajs-310	158	9	receptor	receptor	NOUN
iajs-310	158	10	isoform	isoform	VERB
iajs-310	158	11	467	467	NUM
iajs-310	158	12	|	|	NOUN
iajs-310	158	13	chemistry	chemistry	NOUN
iajs-310	158	14	2014	2014	NUM
iajs-310	158	15	)	)	PUNCT
iajs-310	158	16	عام	عام	ADP
iajs-310	158	17	3(العدد	3(العدد	NUM
iajs-310	158	18	27المجلد	27المجلد	NUM
iajs-310	158	19	مجلة	مجلة	VERB
iajs-310	158	20	إبن	إبن	NOUN
iajs-310	158	21	الھيثم	الھيثم	NOUN
iajs-310	158	22	للعلوم	للعلوم	NOUN
iajs-310	158	23	الصرفة	الصرفة	NOUN
iajs-310	159	1	و	و	PRON
iajs-310	159	2	التطبيقية	التطبيقية	ADJ
iajs-310	159	3	ibn	ibn	PROPN
iajs-310	159	4	al	al	PROPN
iajs-310	159	5	-	-	PUNCT
iajs-310	159	6	haitham	haitham	PROPN
iajs-310	159	7	jour	jour	X
iajs-310	159	8	.	.	PROPN
iajs-310	159	9	for	for	ADP
iajs-310	159	10	pure	pure	ADJ
iajs-310	159	11	&	&	CCONJ
iajs-310	159	12	appl	appl	PROPN
iajs-310	159	13	.	.	PUNCT
iajs-310	160	1	sci	sci	PROPN
iajs-310	160	2	.	.	PUNCT
iajs-310	160	3	vol	vol	NOUN
iajs-310	160	4	.	.	PROPN
iajs-310	161	1	27	27	NUM
iajs-310	161	2	(	(	PUNCT
iajs-310	161	3	3	3	NUM
iajs-310	161	4	)	)	PUNCT
iajs-310	161	5	2014	2014	NUM
iajs-310	161	6	(	(	PUNCT
iajs-310	161	7	ob	ob	NOUN
iajs-310	161	8	-	-	PUNCT
iajs-310	161	9	rb	rb	ADJ
iajs-310	161	10	)	)	PUNCT
iajs-310	161	11	mrna	mrna	NOUN
iajs-310	161	12	between	between	ADP
iajs-310	161	13	advanced	advanced	ADJ
iajs-310	161	14	and	and	CCONJ
iajs-310	161	15	minimally	minimally	ADV
iajs-310	161	16	affected	affected	ADJ
iajs-310	161	17	osteoarthritic	osteoarthritic	ADJ
iajs-310	161	18	cartilage	cartilage	NOUN
iajs-310	161	19	;	;	PUNCT
iajs-310	161	20	effect	effect	NOUN
iajs-310	161	21	on	on	ADP
iajs-310	161	22	cartilage	cartilage	NOUN
iajs-310	161	23	metabolism	metabolism	NOUN
iajs-310	161	24	"	"	PUNCT
iajs-310	161	25	.	.	PUNCT
iajs-310	162	1	osteoarthritis	osteoarthritis	PROPN
iajs-310	162	2	cartilage.;15(8):872–83	cartilage.;15(8):872–83	PROPN
iajs-310	162	3	.	.	PROPN
iajs-310	163	1	27	27	NUM
iajs-310	163	2	keating	keating	NOUN
iajs-310	163	3	,	,	PUNCT
iajs-310	163	4	gm	gm	PROPN
iajs-310	163	5	;	;	PUNCT
iajs-310	163	6	.	.	PUNCT
iajs-310	163	7	(	(	PUNCT
iajs-310	163	8	2008	2008	NUM
iajs-310	163	9	)	)	PUNCT
iajs-310	163	10	.	.	PUNCT
iajs-310	164	1	"	"	PUNCT
iajs-310	164	2	mecasermin	mecasermin	NOUN
iajs-310	164	3	"	"	PUNCT
iajs-310	164	4	.	.	PUNCT
iajs-310	165	1	biodrugs	biodrug	NOUN
iajs-310	165	2	22	22	NUM
iajs-310	165	3	(	(	PUNCT
iajs-310	165	4	3	3	NUM
iajs-310	165	5	):	):	PUNCT
iajs-310	165	6	177–88	177–88	NUM
iajs-310	165	7	.	.	PUNCT
iajs-310	166	1	28rajpathak	28rajpathak	NUM
iajs-310	166	2	,	,	PUNCT
iajs-310	166	3	sn	sn	PROPN
iajs-310	166	4	.	.	PUNCT
iajs-310	166	5	;	;	PUNCT
iajs-310	166	6	gunter	gunter	NOUN
iajs-310	166	7	,	,	PUNCT
iajs-310	166	8	mj.;and	mj.;and	VERB
iajs-310	166	9	wylie	wylie	PROPN
iajs-310	166	10	-	-	PUNCT
iajs-310	166	11	rosett	rosett	NOUN
iajs-310	166	12	,	,	PUNCT
iajs-310	166	13	j.	j.	PROPN
iajs-310	166	14	;	;	PUNCT
iajs-310	166	15	(	(	PUNCT
iajs-310	166	16	2009	2009	NUM
iajs-310	166	17	)	)	PUNCT
iajs-310	166	18	"	"	PUNCT
iajs-310	166	19	the	the	DET
iajs-310	166	20	role	role	NOUN
iajs-310	166	21	of	of	ADP
iajs-310	166	22	insulin	insulin	NOUN
iajs-310	166	23	-	-	PUNCT
iajs-310	166	24	like	like	ADJ
iajs-310	166	25	growth	growth	NOUN
iajs-310	166	26	factor	factor	NOUN
iajs-310	166	27	-	-	PUNCT
iajs-310	166	28	i	i	PROPN
iajs-310	166	29	and	and	CCONJ
iajs-310	166	30	its	its	PRON
iajs-310	166	31	binding	bind	VERB
iajs-310	166	32	proteins	protein	NOUN
iajs-310	166	33	in	in	ADP
iajs-310	166	34	glucose	glucose	NOUN
iajs-310	166	35	homeostasis	homeostasis	NOUN
iajs-310	166	36	and	and	CCONJ
iajs-310	166	37	type	type	NOUN
iajs-310	166	38	2	2	NUM
iajs-310	166	39	diabetes	diabetes	NOUN
iajs-310	166	40	"	"	PUNCT
iajs-310	166	41	.	.	PUNCT
iajs-310	167	1	diabetes	diabete	VERB
iajs-310	167	2	metab	metab	NOUN
iajs-310	167	3	res	re	NOUN
iajs-310	167	4	rev	rev	X
iajs-310	167	5	;	;	PUNCT
iajs-310	167	6	25:3	25:3	NUM
iajs-310	167	7	.	.	PROPN
iajs-310	167	8	29lingling	29lingling	NUM
iajs-310	167	9	xian	xian	NOUN
iajs-310	167	10	.	.	PUNCT
iajs-310	168	1	;	;	PUNCT
iajs-310	168	2	xiangwei	xiangwei	PROPN
iajs-310	168	3	wu	wu	PROPN
iajs-310	168	4	.	.	PUNCT
iajs-310	168	5	;	;	PUNCT
iajs-310	168	6	lijuan	lijuan	PROPN
iajs-310	168	7	pang	pang	PROPN
iajs-310	168	8	.	.	PUNCT
iajs-310	168	9	;	;	PUNCT
iajs-310	168	10	and	and	CCONJ
iajs-310	168	11	michael	michael	PROPN
iajs-310	168	12	lou1	lou1	PROPN
iajs-310	168	13	.	.	PUNCT
iajs-310	169	1	(	(	PUNCT
iajs-310	169	2	2012	2012	NUM
iajs-310	169	3	)	)	PUNCT
iajs-310	169	4	"	"	PUNCT
iajs-310	169	5	matrix	matrix	NOUN
iajs-310	169	6	igf-1	igf-1	NOUN
iajs-310	169	7	regulates	regulate	VERB
iajs-310	169	8	bone	bone	NOUN
iajs-310	169	9	mass	mass	NOUN
iajs-310	169	10	by	by	ADP
iajs-310	169	11	activation	activation	NOUN
iajs-310	169	12	of	of	ADP
iajs-310	169	13	mtor	mtor	NOUN
iajs-310	169	14	in	in	ADP
iajs-310	169	15	mesenchymal	mesenchymal	ADJ
iajs-310	169	16	stem	stem	NOUN
iajs-310	169	17	cells	cell	NOUN
iajs-310	169	18	"	"	PUNCT
iajs-310	169	19	.	.	PUNCT
iajs-310	170	1	nat	nat	PROPN
iajs-310	170	2	med	med	PROPN
iajs-310	170	3	.	.	PROPN
iajs-310	171	1	author	author	PROPN
iajs-310	171	2	manuscript	manuscript	PROPN
iajs-310	171	3	;	;	PUNCT
iajs-310	171	4	july	july	PROPN
iajs-310	171	5	;	;	PUNCT
iajs-310	171	6	18(7	18(7	NUM
iajs-310	171	7	):	):	PUNCT
iajs-310	171	8	1095–1101	1095–1101	NUM
iajs-310	171	9	.	.	PUNCT
iajs-310	172	1	30	30	NUM
iajs-310	172	2	-	-	PUNCT
iajs-310	172	3	callewaert	callewaert	NOUN
iajs-310	172	4	,	,	PUNCT
iajs-310	172	5	f.	f.	PROPN
iajs-310	172	6	;	;	PUNCT
iajs-310	172	7	sinnesael	sinnesael	PROPN
iajs-310	172	8	,	,	PUNCT
iajs-310	172	9	m.;gielen	m.;gielen	PROPN
iajs-310	172	10	e.	e.	PROPN
iajs-310	172	11	;	;	PUNCT
iajs-310	172	12	boonen	boonen	PROPN
iajs-310	172	13	,	,	PUNCT
iajs-310	172	14	s.	s.	PROPN
iajs-310	172	15	;	;	PUNCT
iajs-310	172	16	and	and	CCONJ
iajs-310	172	17	vanders	vander	NOUN
iajs-310	172	18	chueren	chueren	PROPN
iajs-310	172	19	,	,	PUNCT
iajs-310	172	20	d.	d.	PROPN
iajs-310	172	21	(	(	PUNCT
iajs-310	172	22	2010	2010	NUM
iajs-310	172	23	)	)	PUNCT
iajs-310	172	24	"	"	PUNCT
iajs-310	172	25	skeletal	skeletal	ADJ
iajs-310	172	26	sexual	sexual	ADJ
iajs-310	172	27	dimorphism	dimorphism	NOUN
iajs-310	172	28	:	:	PUNCT
iajs-310	172	29	relative	relative	ADJ
iajs-310	172	30	contribution	contribution	NOUN
iajs-310	172	31	of	of	ADP
iajs-310	172	32	sex	sex	NOUN
iajs-310	172	33	steroids	steroid	NOUN
iajs-310	172	34	,	,	PUNCT
iajs-310	172	35	gh	gh	PROPN
iajs-310	172	36	-	-	PUNCT
iajs-310	172	37	igf1	igf1	PROPN
iajs-310	172	38	,	,	PUNCT
iajs-310	172	39	and	and	CCONJ
iajs-310	172	40	mechanical	mechanical	ADJ
iajs-310	172	41	loading	loading	NOUN
iajs-310	172	42	"	"	PUNCT
iajs-310	172	43	.	.	PUNCT
iajs-310	173	1	j.	j.	PROPN
iajs-310	173	2	endocrinol	endocrinol	PROPN
iajs-310	173	3	.	.	PUNCT
iajs-310	174	1	207:127–134	207:127–134	NUM
iajs-310	174	2	.	.	PUNCT
iajs-310	175	1	31russell	31russell	NUM
iajs-310	175	2	,	,	PUNCT
iajs-310	175	3	rc	rc	PROPN
iajs-310	175	4	.	.	PROPN
iajs-310	175	5	;	;	PUNCT
iajs-310	175	6	fang	fang	X
iajs-310	175	7	,	,	PUNCT
iajs-310	175	8	c.	c.	NOUN
iajs-310	175	9	;	;	PUNCT
iajs-310	175	10	and	and	CCONJ
iajs-310	175	11	guan	guan	PROPN
iajs-310	175	12	,	,	PUNCT
iajs-310	175	13	kl	kl	PROPN
iajs-310	175	14	.	.	PUNCT
iajs-310	176	1	(	(	PUNCT
iajs-310	176	2	2011)"an	2011)"an	NUM
iajs-310	176	3	emerging	emerge	VERB
iajs-310	176	4	role	role	NOUN
iajs-310	176	5	for	for	ADP
iajs-310	176	6	tor	tor	NOUN
iajs-310	176	7	signaling	signal	VERB
iajs-310	176	8	in	in	ADP
iajs-310	176	9	mammalian	mammalian	ADJ
iajs-310	176	10	tissue	tissue	NOUN
iajs-310	176	11	and	and	CCONJ
iajs-310	176	12	stem	stem	NOUN
iajs-310	176	13	cell	cell	NOUN
iajs-310	176	14	physiology	physiology	NOUN
iajs-310	176	15	"	"	PUNCT
iajs-310	176	16	.	.	PUNCT
iajs-310	177	1	development	development	NOUN
iajs-310	177	2	.	.	PUNCT
iajs-310	178	1	138:3343–3356	138:3343–3356	X
iajs-310	178	2	.	.	PUNCT
iajs-310	179	1	32claessen	32claessen	NUM
iajs-310	179	2	,	,	PUNCT
iajs-310	179	3	k.m.j.a	k.m.j.a	PROPN
iajs-310	179	4	.	.	PROPN
iajs-310	179	5	;	;	PUNCT
iajs-310	179	6	ramautar	ramautar	NOUN
iajs-310	179	7	,	,	PUNCT
iajs-310	179	8	s.r	s.r	PROPN
iajs-310	179	9	.	.	PROPN
iajs-310	179	10	;	;	PUNCT
iajs-310	179	11	pereira	pereira	PROPN
iajs-310	179	12	,	,	PUNCT
iajs-310	179	13	a.m.	a.m.	ADV
iajs-310	179	14	;	;	PUNCT
iajs-310	179	15	smit	smit	PROPN
iajs-310	179	16	,	,	PUNCT
iajs-310	179	17	j.w.a	j.w.a	ADV
iajs-310	179	18	.	.	PUNCT
iajs-310	179	19	;	;	PUNCT
iajs-310	179	20	biermasz	biermasz	VERB
iajs-310	179	21	,	,	PUNCT
iajs-310	179	22	n.r	n.r	PROPN
iajs-310	179	23	.	.	PUNCT
iajs-310	179	24	;	;	PUNCT
iajs-310	179	25	and	and	CCONJ
iajs-310	179	26	kloppenburg	kloppenburg	PROPN
iajs-310	179	27	,	,	PUNCT
iajs-310	179	28	m.	m.	NOUN
iajs-310	179	29	;	;	PUNCT
iajs-310	179	30	(	(	PUNCT
iajs-310	179	31	2012	2012	NUM
iajs-310	179	32	)	)	PUNCT
iajs-310	179	33	"	"	PUNCT
iajs-310	179	34	relationship	relationship	NOUN
iajs-310	179	35	between	between	ADP
iajs-310	179	36	insulin	insulin	NOUN
iajs-310	179	37	-	-	PUNCT
iajs-310	179	38	like	like	ADJ
iajs-310	179	39	growth	growth	NOUN
iajs-310	179	40	factor-1	factor-1	NUM
iajs-310	179	41	and	and	CCONJ
iajs-310	179	42	radiographic	radiographic	ADJ
iajs-310	179	43	disease	disease	NOUN
iajs-310	179	44	in	in	ADP
iajs-310	179	45	patients	patient	NOUN
iajs-310	179	46	with	with	ADP
iajs-310	179	47	primary	primary	ADJ
iajs-310	179	48	osteoarthritis	osteoarthritis	NOUN
iajs-310	179	49	"	"	PUNCT
iajs-310	179	50	.	.	PUNCT
iajs-310	180	1	a	a	DET
iajs-310	180	2	systematic	systematic	ADJ
iajs-310	180	3	review	review	NOUN
iajs-310	180	4	osteoarthritis	osteoarthritis	NOUN
iajs-310	180	5	society	society	NOUN
iajs-310	180	6	international	international	ADJ
iajs-310	180	7	20	20	NUM
iajs-310	180	8	,	,	PUNCT
iajs-310	180	9	2	2	NUM
iajs-310	180	10	,	,	PUNCT
iajs-310	180	11	79–86	79–86	NUM
iajs-310	180	12	.	.	PUNCT
iajs-310	181	1	33biermasz	33biermasz	NUM
iajs-310	181	2	,	,	PUNCT
iajs-310	181	3	n.r	n.r	PROPN
iajs-310	181	4	..	..	PROPN
iajs-310	181	5	;	;	PUNCT
iajs-310	181	6	wassenaar	wassenaar	NOUN
iajs-310	181	7	,	,	PUNCT
iajs-310	181	8	m.j	m.j	PROPN
iajs-310	181	9	.	.	PROPN
iajs-310	181	10	;	;	PUNCT
iajs-310	181	11	van	van	PROPN
iajs-310	181	12	,	,	PUNCT
iajs-310	181	13	a.a	a.a	PROPN
iajs-310	181	14	.	.	PROPN
iajs-310	181	15	;	;	PUNCT
iajs-310	181	16	der	der	ADJ
iajs-310	181	17	klaauw	klaauw	NOUN
iajs-310	181	18	.	.	PUNCT
iajs-310	181	19	;	;	PUNCT
iajs-310	182	1	pereira	pereira	PROPN
iajs-310	182	2	,	,	PUNCT
iajs-310	182	3	a.m	a.m	PROPN
iajs-310	182	4	..	..	PROPN
iajs-310	182	5	;	;	PUNCT
iajs-310	182	6	smit	smit	PROPN
iajs-310	182	7	,	,	PUNCT
iajs-310	182	8	j.w	j.w	PROPN
iajs-310	182	9	..	..	PUNCT
iajs-310	182	10	;	;	PUNCT
iajs-310	182	11	and	and	CCONJ
iajs-310	182	12	roelfsema	roelfsema	VERB
iajs-310	182	13	,	,	PUNCT
iajs-310	182	14	f	f	PROPN
iajs-310	182	15	..	..	PUNCT
iajs-310	182	16	;	;	PUNCT
iajs-310	182	17	(	(	PUNCT
iajs-310	182	18	2009	2009	NUM
iajs-310	182	19	)	)	PUNCT
iajs-310	182	20	"	"	PUNCT
iajs-310	182	21	pretreatment	pretreatment	NOUN
iajs-310	182	22	insulin	insulin	NOUN
iajs-310	182	23	-	-	PUNCT
iajs-310	182	24	like	like	ADJ
iajs-310	182	25	growth	growth	NOUN
iajs-310	182	26	factor	factor	NOUN
iajs-310	182	27	-	-	PUNCT
iajs-310	182	28	i	i	PRON
iajs-310	182	29	concentrations	concentration	NOUN
iajs-310	182	30	predict	predict	VERB
iajs-310	182	31	radiographic	radiographic	ADJ
iajs-310	182	32	osteoarthritis	osteoarthritis	NOUN
iajs-310	182	33	in	in	ADP
iajs-310	182	34	acromegalic	acromegalic	ADJ
iajs-310	182	35	patients	patient	NOUN
iajs-310	182	36	with	with	ADP
iajs-310	182	37	long	long	ADJ
iajs-310	182	38	-	-	PUNCT
iajs-310	182	39	term	term	NOUN
iajs-310	182	40	cured	cure	VERB
iajs-310	182	41	disease	disease	NOUN
iajs-310	182	42	"	"	PUNCT
iajs-310	182	43	.	.	PUNCT
iajs-310	183	1	j	j	PROPN
iajs-310	183	2	clin	clin	PROPN
iajs-310	183	3	endocrinol	endocrinol	PROPN
iajs-310	183	4	metab	metab	NOUN
iajs-310	183	5	,	,	PUNCT
iajs-310	183	6	94	94	NUM
iajs-310	183	7	,	,	PUNCT
iajs-310	183	8	.	.	PUNCT
iajs-310	184	1	2374–2379	2374–2379	NUM
iajs-310	184	2	.	.	PUNCT
iajs-310	185	1	34brugts	34brugts	NUM
iajs-310	185	2	,	,	PUNCT
iajs-310	185	3	m.p	m.p	PROPN
iajs-310	185	4	..	..	PROPN
iajs-310	185	5	;	;	PUNCT
iajs-310	185	6	ranke	ranke	PROPN
iajs-310	185	7	,	,	PUNCT
iajs-310	185	8	m.b	m.b	PROPN
iajs-310	185	9	..	..	PROPN
iajs-310	185	10	;	;	PUNCT
iajs-310	185	11	hofland	hofland	NOUN
iajs-310	185	12	,	,	PUNCT
iajs-310	185	13	l.j	l.j	PROPN
iajs-310	185	14	..	..	PROPN
iajs-310	185	15	;	;	PUNCT
iajs-310	185	16	van	van	PROPN
iajs-310	185	17	der	der	PROPN
iajs-310	185	18	wansem	wansem	PROPN
iajs-310	185	19	,	,	PUNCT
iajs-310	185	20	k	k	PROPN
iajs-310	185	21	..	..	PUNCT
iajs-310	185	22	;	;	PUNCT
iajs-310	185	23	weber	weber	PROPN
iajs-310	185	24	,	,	PUNCT
iajs-310	185	25	k	k	PROPN
iajs-310	185	26	..	..	PUNCT
iajs-310	185	27	;	;	PUNCT
iajs-310	185	28	and	and	CCONJ
iajs-310	185	29	frystyk	frystyk	NOUN
iajs-310	185	30	,	,	PUNCT
iajs-310	185	31	j	j	PROPN
iajs-310	185	32	..	..	PUNCT
iajs-310	185	33	;	;	PUNCT
iajs-310	185	34	(	(	PUNCT
iajs-310	185	35	2008	2008	NUM
iajs-310	185	36	)	)	PUNCT
iajs-310	185	37	"	"	PUNCT
iajs-310	185	38	normal	normal	ADJ
iajs-310	185	39	values	value	NOUN
iajs-310	185	40	of	of	ADP
iajs-310	185	41	circulating	circulate	VERB
iajs-310	185	42	insulin	insulin	NOUN
iajs-310	185	43	-	-	PUNCT
iajs-310	185	44	like	like	ADJ
iajs-310	185	45	growth	growth	NOUN
iajs-310	185	46	factor-1	factor-1	NUM
iajs-310	185	47	bioactivity	bioactivity	NOUN
iajs-310	185	48	in	in	ADP
iajs-310	185	49	the	the	DET
iajs-310	185	50	healthy	healthy	ADJ
iajs-310	185	51	population	population	NOUN
iajs-310	185	52	"	"	PUNCT
iajs-310	185	53	.	.	PUNCT
iajs-310	186	1	comparison	comparison	NOUN
iajs-310	186	2	with	with	ADP
iajs-310	186	3	five	five	NUM
iajs-310	186	4	widely	widely	ADV
iajs-310	186	5	used	use	VERB
iajs-310	186	6	igf-1	igf-1	NUM
iajs-310	186	7	immunoassaysj	immunoassaysj	NOUN
iajs-310	186	8	clin	clin	PROPN
iajs-310	186	9	endocrinol	endocrinol	NOUN
iajs-310	186	10	metab	metab	NOUN
iajs-310	186	11	,	,	PUNCT
iajs-310	186	12	93	93	NUM
iajs-310	186	13	(	(	PUNCT
iajs-310	186	14	7	7	NUM
iajs-310	186	15	.	.	X
iajs-310	186	16	2539–2545	2539–2545	NUM
iajs-310	186	17	.	.	PUNCT
iajs-310	187	1	35	35	NUM
iajs-310	187	2	-	-	PUNCT
iajs-310	187	3	janssen	janssen	PROPN
iajs-310	187	4	,	,	PUNCT
iajs-310	187	5	j	j	PROPN
iajs-310	187	6	,	,	PUNCT
iajs-310	187	7	a.	a.	NOUN
iajs-310	187	8	;	;	PUNCT
iajs-310	187	9	and	and	CCONJ
iajs-310	187	10	lamberts	lambert	NOUN
iajs-310	187	11	,	,	PUNCT
iajs-310	187	12	s	s	PROPN
iajs-310	187	13	,	,	PUNCT
iajs-310	187	14	w.	w.	NOUN
iajs-310	187	15	;	;	PUNCT
iajs-310	187	16	(	(	PUNCT
iajs-310	187	17	2008	2008	NUM
iajs-310	187	18	)	)	PUNCT
iajs-310	187	19	"	"	PUNCT
iajs-310	187	20	the	the	DET
iajs-310	187	21	role	role	NOUN
iajs-310	187	22	of	of	ADP
iajs-310	187	23	igf-1	igf-1	NOUN
iajs-310	187	24	development	development	NOUN
iajs-310	187	25	of	of	ADP
iajs-310	187	26	cardiovascular	cardiovascular	ADJ
iajs-310	187	27	disease	disease	NOUN
iajs-310	187	28	in	in	ADP
iajs-310	187	29	type	type	NOUN
iajs-310	187	30	2	2	NUM
iajs-310	187	31	diabetes	diabetes	NOUN
iajs-310	187	32	mellitus	mellitus	NOUN
iajs-310	187	33	"	"	PUNCT
iajs-310	187	34	.	.	PUNCT
iajs-310	187	35	is	be	AUX
iajs-310	187	36	prevention	prevention	NOUN
iajs-310	187	37	possible	possible	ADJ
iajs-310	187	38	.	.	PUNCT
iajs-310	188	1	euro	euro	PROPN
iajs-310	188	2	j	j	PROPN
iajs-310	188	3	endoc	endoc	ADV
iajs-310	188	4	.	.	PUNCT
iajs-310	189	1	146	146	NUM
iajs-310	189	2	:	:	PUNCT
iajs-310	189	3	467	467	NUM
iajs-310	189	4	-	-	SYM
iajs-310	189	5	477	477	NUM
iajs-310	189	6	.	.	PUNCT
iajs-310	189	7	table	table	NOUN
iajs-310	189	8	(	(	PUNCT
iajs-310	189	9	1	1	NUM
iajs-310	189	10	):	):	PUNCT
iajs-310	189	11	levels	level	NOUN
iajs-310	189	12	of	of	ADP
iajs-310	189	13	aip	aip	PROPN
iajs-310	189	14	in	in	ADP
iajs-310	189	15	different	different	ADJ
iajs-310	189	16	patient	patient	NOUN
iajs-310	189	17	groups	group	NOUN
iajs-310	189	18	compared	compare	VERB
iajs-310	189	19	with	with	ADP
iajs-310	189	20	control	control	NOUN
iajs-310	189	21	variables	variable	NOUN
iajs-310	189	22	aip	aip	PROPN
iajs-310	189	23	value	value	NOUN
iajs-310	189	24	dm	dm	INTJ
iajs-310	189	25	oa	oa	INTJ
iajs-310	190	1	dm	dm	PROPN
iajs-310	190	2	+	+	CCONJ
iajs-310	190	3	oa	oa	PROPN
iajs-310	190	4	control	control	NOUN
iajs-310	190	5	sample	sample	PROPN
iajs-310	190	6	no	no	INTJ
iajs-310	190	7	.	.	NOUN
iajs-310	191	1	20	20	NUM
iajs-310	191	2	24	24	NUM
iajs-310	191	3	24	24	NUM
iajs-310	191	4	20	20	NUM
iajs-310	191	5	mean	mean	NOUN
iajs-310	191	6	±	±	NUM
iajs-310	191	7	sd	sd	ADP
iajs-310	191	8	0.27±0.19	0.27±0.19	NOUN
iajs-310	191	9	0.21±0.17	0.21±0.17	PROPN
iajs-310	191	10	0.34±0.20	0.34±0.20	NUM
iajs-310	191	11	0.19±0.11	0.19±0.11	ADJ
iajs-310	192	1	range	range	NOUN
iajs-310	192	2	0.010	0.010	NUM
iajs-310	192	3	-	-	SYM
iajs-310	192	4	0.600	0.600	NUM
iajs-310	192	5	0.021	0.021	NUM
iajs-310	192	6	-	-	PUNCT
iajs-310	192	7	0.711	0.711	NUM
iajs-310	192	8	0.030	0.030	NUM
iajs-310	192	9	-	-	SYM
iajs-310	192	10	0.720	0.720	NUM
iajs-310	192	11	0.051	0.051	NUM
iajs-310	192	12	-	-	PUNCT
iajs-310	192	13	0.376	0.376	NUM
iajs-310	192	14	p	p	NOUN
iajs-310	192	15	against	against	ADP
iajs-310	192	16	control	control	NOUN
iajs-310	192	17	0.096	0.096	NUM
iajs-310	192	18	0.028	0.028	NUM
iajs-310	192	19	0.014	0.014	NUM
iajs-310	192	20	p	p	NOUN
iajs-310	192	21	against	against	ADP
iajs-310	192	22	total	total	ADJ
iajs-310	192	23	0.019	0.019	NUM
iajs-310	192	24	p	p	NOUN
iajs-310	192	25	value	value	NOUN
iajs-310	192	26	<	<	X
iajs-310	192	27	0.05	0.05	NUM
iajs-310	192	28	represents	represent	VERB
iajs-310	192	29	significant	significant	ADJ
iajs-310	192	30	.	.	PUNCT
iajs-310	193	1	468	468	NUM
iajs-310	194	1	|	|	ADV
iajs-310	194	2	chemistry	chemistry	NOUN
iajs-310	194	3	2014	2014	NUM
iajs-310	194	4	)	)	PUNCT
iajs-310	194	5	عام	عام	ADP
iajs-310	194	6	3(العدد	3(العدد	NUM
iajs-310	194	7	27المجلد	27المجلد	NUM
iajs-310	194	8	مجلة	مجلة	VERB
iajs-310	194	9	إبن	إبن	NOUN
iajs-310	194	10	الھيثم	الھيثم	NOUN
iajs-310	194	11	للعلوم	للعلوم	NOUN
iajs-310	194	12	الصرفة	الصرفة	NOUN
iajs-310	195	1	و	و	PRON
iajs-310	195	2	التطبيقية	التطبيقية	ADJ
iajs-310	195	3	ibn	ibn	PROPN
iajs-310	195	4	al	al	PROPN
iajs-310	195	5	-	-	PUNCT
iajs-310	195	6	haitham	haitham	PROPN
iajs-310	195	7	jour	jour	X
iajs-310	195	8	.	.	PROPN
iajs-310	195	9	for	for	ADP
iajs-310	195	10	pure	pure	ADJ
iajs-310	195	11	&	&	CCONJ
iajs-310	195	12	appl	appl	PROPN
iajs-310	195	13	.	.	PUNCT
iajs-310	196	1	sci	sci	PROPN
iajs-310	196	2	.	.	PUNCT
iajs-310	196	3	vol	vol	NOUN
iajs-310	196	4	.	.	PROPN
iajs-310	197	1	27	27	NUM
iajs-310	197	2	(	(	PUNCT
iajs-310	197	3	3	3	NUM
iajs-310	197	4	)	)	PUNCT
iajs-310	197	5	2014	2014	NUM
iajs-310	197	6	table	table	NOUN
iajs-310	197	7	(	(	PUNCT
iajs-310	197	8	2	2	NUM
iajs-310	197	9	)	)	PUNCT
iajs-310	197	10	levels	level	NOUN
iajs-310	197	11	of	of	ADP
iajs-310	197	12	leptin	leptin	NOUN
iajs-310	197	13	in	in	ADP
iajs-310	197	14	different	different	ADJ
iajs-310	197	15	patient	patient	NOUN
iajs-310	197	16	groups	group	NOUN
iajs-310	197	17	compared	compare	VERB
iajs-310	197	18	with	with	ADP
iajs-310	197	19	control	control	NOUN
iajs-310	197	20	variables	variable	NOUN
iajs-310	197	21	leptin	leptin	NOUN
iajs-310	197	22	level	level	NOUN
iajs-310	197	23	(	(	PUNCT
iajs-310	197	24	ng	ng	NOUN
iajs-310	197	25	/	/	SYM
iajs-310	197	26	ml	ml	PROPN
iajs-310	197	27	)	)	PUNCT
iajs-310	197	28	dm	dm	NOUN
iajs-310	197	29	oa	oa	INTJ
iajs-310	198	1	dm	dm	PROPN
iajs-310	198	2	+	+	CCONJ
iajs-310	198	3	oa	oa	PROPN
iajs-310	198	4	control	control	NOUN
iajs-310	198	5	sample	sample	PROPN
iajs-310	198	6	no	no	INTJ
iajs-310	198	7	.	.	NOUN
iajs-310	199	1	20	20	NUM
iajs-310	199	2	24	24	NUM
iajs-310	199	3	24	24	NUM
iajs-310	199	4	20	20	NUM
iajs-310	199	5	mean	mean	NOUN
iajs-310	199	6	±	±	NUM
iajs-310	199	7	sd	sd	ADP
iajs-310	199	8	37.1±23.10	37.1±23.10	NOUN
iajs-310	199	9	22.4±12.93	22.4±12.93	NUM
iajs-310	199	10	37.4±25.64	37.4±25.64	NUM
iajs-310	199	11	14.23±7.53	14.23±7.53	NUM
iajs-310	199	12	range	range	NOUN
iajs-310	199	13	3.9	3.9	NUM
iajs-310	199	14	-	-	SYM
iajs-310	199	15	49.7	49.7	NUM
iajs-310	199	16	7.5	7.5	NUM
iajs-310	199	17	-	-	SYM
iajs-310	199	18	82.0	82.0	NUM
iajs-310	199	19	5.6	5.6	NUM
iajs-310	199	20	-	-	SYM
iajs-310	199	21	86.6	86.6	NUM
iajs-310	199	22	7.5	7.5	NUM
iajs-310	199	23	-	-	SYM
iajs-310	199	24	39.1	39.1	NUM
iajs-310	199	25	p	p	NOUN
iajs-310	199	26	against	against	ADP
iajs-310	199	27	control	control	NOUN
iajs-310	199	28	0.092	0.092	NUM
iajs-310	199	29	0.001	0.001	NUM
iajs-310	199	30	0.0001	0.0001	NUM
iajs-310	199	31	p	p	NOUN
iajs-310	199	32	against	against	ADP
iajs-310	199	33	total	total	ADJ
iajs-310	199	34	0.0001	0.0001	NUM
iajs-310	199	35	p	p	NOUN
iajs-310	199	36	value	value	NOUN
iajs-310	199	37	<	<	X
iajs-310	199	38	0.05	0.05	NUM
iajs-310	199	39	represents	represent	VERB
iajs-310	199	40	significant	significant	ADJ
iajs-310	199	41	.	.	PUNCT
iajs-310	199	42	table	table	NOUN
iajs-310	199	43	(	(	PUNCT
iajs-310	199	44	3	3	NUM
iajs-310	199	45	):	):	PUNCT
iajs-310	199	46	levels	level	NOUN
iajs-310	199	47	of	of	ADP
iajs-310	199	48	igf-1	igf-1	NOUN
iajs-310	199	49	in	in	ADP
iajs-310	199	50	different	different	ADJ
iajs-310	199	51	patient	patient	NOUN
iajs-310	199	52	groups	group	NOUN
iajs-310	199	53	compared	compare	VERB
iajs-310	199	54	with	with	ADP
iajs-310	199	55	control	control	NOUN
iajs-310	199	56	variables	variable	NOUN
iajs-310	199	57	ifg-1	ifg-1	DET
iajs-310	199	58	level	level	NOUN
iajs-310	199	59	(	(	PUNCT
iajs-310	199	60	ng	ng	NOUN
iajs-310	199	61	/	/	SYM
iajs-310	199	62	ml	ml	PROPN
iajs-310	199	63	)	)	PUNCT
iajs-310	200	1	dm	dm	NOUN
iajs-310	200	2	oa	oa	INTJ
iajs-310	201	1	dm	dm	PROPN
iajs-310	201	2	+	+	CCONJ
iajs-310	201	3	oa	oa	PROPN
iajs-310	201	4	control	control	NOUN
iajs-310	201	5	sample	sample	PROPN
iajs-310	201	6	no	no	INTJ
iajs-310	201	7	.	.	NOUN
iajs-310	202	1	20	20	NUM
iajs-310	202	2	24	24	NUM
iajs-310	202	3	24	24	NUM
iajs-310	202	4	20	20	NUM
iajs-310	202	5	mean	mean	NOUN
iajs-310	202	6	±	±	NUM
iajs-310	202	7	sd	sd	ADP
iajs-310	202	8	127.8±24.07	127.8±24.07	NUM
iajs-310	202	9	138.0±31.86	138.0±31.86	NUM
iajs-310	202	10	98.71±17.05	98.71±17.05	NUM
iajs-310	202	11	298.2±56.14	298.2±56.14	NUM
iajs-310	202	12	range	range	NOUN
iajs-310	202	13	94	94	NUM
iajs-310	202	14	-	-	SYM
iajs-310	202	15	195	195	NUM
iajs-310	202	16	95	95	NUM
iajs-310	202	17	-	-	SYM
iajs-310	202	18	166	166	NUM
iajs-310	202	19	79	79	NUM
iajs-310	202	20	-	-	SYM
iajs-310	202	21	141	141	NUM
iajs-310	202	22	208	208	NUM
iajs-310	202	23	-	-	SYM
iajs-310	202	24	395	395	NUM
iajs-310	202	25	p	p	NOUN
iajs-310	202	26	against	against	ADP
iajs-310	202	27	control	control	NOUN
iajs-310	202	28	0.0001	0.0001	NUM
iajs-310	202	29	0.0001	0.0001	NUM
iajs-310	202	30	0.0001	0.0001	NUM
iajs-310	202	31	p	p	NOUN
iajs-310	202	32	against	against	ADP
iajs-310	202	33	total	total	ADJ
iajs-310	202	34	0.0001	0.0001	NUM
iajs-310	202	35	p	p	NOUN
iajs-310	202	36	value	value	NOUN
iajs-310	202	37	<	<	X
iajs-310	202	38	0.05	0.05	NUM
iajs-310	202	39	represents	represent	VERB
iajs-310	202	40	significant	significant	ADJ
iajs-310	202	41	.	.	PUNCT
iajs-310	203	1	469	469	NUM
iajs-310	203	2	|	|	ADV
iajs-310	203	3	chemistry	chemistry	NOUN
iajs-310	203	4	2014	2014	NUM
iajs-310	203	5	)	)	PUNCT
iajs-310	203	6	عام	عام	ADP
iajs-310	203	7	3(العدد	3(العدد	NUM
iajs-310	203	8	27المجلد	27المجلد	NUM
iajs-310	203	9	مجلة	مجلة	VERB
iajs-310	203	10	إبن	إبن	NOUN
iajs-310	203	11	الھيثم	الھيثم	NOUN
iajs-310	203	12	للعلوم	للعلوم	NOUN
iajs-310	203	13	الصرفة	الصرفة	NOUN
iajs-310	204	1	و	و	PRON
iajs-310	204	2	التطبيقية	التطبيقية	ADJ
iajs-310	204	3	ibn	ibn	PROPN
iajs-310	204	4	al	al	PROPN
iajs-310	204	5	-	-	PUNCT
iajs-310	204	6	haitham	haitham	PROPN
iajs-310	204	7	jour	jour	X
iajs-310	204	8	.	.	PROPN
iajs-310	204	9	for	for	ADP
iajs-310	204	10	pure	pure	ADJ
iajs-310	204	11	&	&	CCONJ
iajs-310	204	12	appl	appl	PROPN
iajs-310	204	13	.	.	PUNCT
iajs-310	205	1	sci	sci	PROPN
iajs-310	205	2	.	.	PUNCT
iajs-310	205	3	vol	vol	NOUN
iajs-310	205	4	.	.	PROPN
iajs-310	206	1	27	27	NUM
iajs-310	206	2	(	(	PUNCT
iajs-310	206	3	3	3	NUM
iajs-310	206	4	)	)	PUNCT
iajs-310	206	5	2014	2014	NUM
iajs-310	206	6	ھرمون	ھرمون	NOUN
iajs-310	206	7	النمو	النمو	PROPN
iajs-310	206	8	الشبيه	الشبيه	PROPN
iajs-310	206	9	باالنسولين	باالنسولين	PROPN
iajs-310	206	10	واللبتين	واللبتين	NOUN
iajs-310	206	11	ومؤشر	ومؤشر	NOUN
iajs-310	206	12	معصد	معصد	ADJ
iajs-310	206	13	البالزما	البالزما	NOUN
iajs-310	206	14	في	في	SCONJ
iajs-310	206	15	عالقة	عالقة	PROPN
iajs-310	206	16	مرضى	مرضى	PROPN
iajs-310	206	17	سوفان	سوفان	NOUN
iajs-310	206	18	المفاصل	المفاصل	VERB
iajs-310	206	19	المصابين	المصابين	PROPN
iajs-310	206	20	وغير	وغير	PROPN
iajs-310	206	21	المصابين	المصابين	PROPN
iajs-310	206	22	بداء	بداء	ADV
iajs-310	206	23	السكري	السكري	PROPN
iajs-310	206	24	من	من	PRON
iajs-310	206	25	النوع	النوع	PROPN
iajs-310	206	26	الثاني	الثاني	PROPN
iajs-310	206	27	لمياء	لمياء	PROPN
iajs-310	206	28	شاكر	شاكر	NOUN
iajs-310	206	29	عاشور	عاشور	PROPN
iajs-310	206	30	شعبة	شعبة	PROPN
iajs-310	206	31	العلوم	العلوم	PROPN
iajs-310	206	32	االساسية	االساسية	NOUN
iajs-310	206	33	/	/	SYM
iajs-310	206	34	كلية	كلية	NOUN
iajs-310	206	35	الزراعة	الزراعة	NOUN
iajs-310	206	36	/جامعة	/جامعة	PUNCT
iajs-310	206	37	بغداد	بغداد	PROPN
iajs-310	206	38	طارق	طارق	PROPN
iajs-310	206	39	محمد	محمد	PROPN
iajs-310	206	40	علي	علي	NOUN
iajs-310	206	41	رجب	رجب	VERB
iajs-310	206	42	قسم	قسم	PROPN
iajs-310	206	43	الكيمياء	الكيمياء	PROPN
iajs-310	206	44	/	/	SYM
iajs-310	206	45	كلية	كلية	NOUN
iajs-310	206	46	التربية	التربية	NOUN
iajs-310	206	47	ابن	ابن	PROPN
iajs-310	206	48	الھيثم	الھيثم	PROPN
iajs-310	206	49	للعلوم	للعلوم	PROPN
iajs-310	206	50	الصرفة	الصرفة	NOUN
iajs-310	206	51	(	(	PUNCT
iajs-310	206	52	ابن	ابن	PROPN
iajs-310	206	53	الھيثم	الھيثم	PROPN
iajs-310	206	54	)	)	PUNCT
iajs-310	206	55	/	/	SYM
iajs-310	206	56	جامعة	جامعة	PROPN
iajs-310	206	57	بغداد	بغداد	PROPN
iajs-310	206	58	حامد	حامد	PROPN
iajs-310	206	59	حسن	حسن	PROPN
iajs-310	206	60	غفوري	غفوري	VERB
iajs-310	206	61	قسم	قسم	PROPN
iajs-310	206	62	الكيمياء	الكيمياء	PROPN
iajs-310	206	63	السريرية	السريرية	PROPN
iajs-310	206	64	/	/	SYM
iajs-310	206	65	كلية	كلية	NOUN
iajs-310	206	66	الصفوة	الصفوة	NOUN
iajs-310	206	67	الجامعة	الجامعة	PROPN
iajs-310	206	68	/	/	SYM
iajs-310	207	1	كربالء	كربالء	NOUN
iajs-310	207	2	2014	2014	NUM
iajs-310	207	3	ايلول	ايلول	NOUN
iajs-310	207	4	29	29	NUM
iajs-310	207	5	,	,	PUNCT
iajs-310	207	6	قبل	قبل	PROPN
iajs-310	207	7	البحث	البحث	VERB
iajs-310	207	8	في	في	ADP
iajs-310	207	9	:	:	PUNCT
iajs-310	207	10	2014	2014	NUM
iajs-310	207	11	ايلول	ايلول	NOUN
iajs-310	207	12	1	1	NUM
iajs-310	207	13	:	:	PUNCT
iajs-310	207	14	استلم	استلم	PROPN
iajs-310	207	15	البحث	البحث	VERB
iajs-310	207	16	في	في	ADP
iajs-310	207	17	الخالصة	الخالصة	PROPN
iajs-310	207	18	ثر	ثر	VERB
iajs-310	207	19	في	في	SCONJ
iajs-310	207	20	منع	منع	PROPN
iajs-310	207	21	ھرمون	ھرمون	PROPN
iajs-310	207	22	النمو	النمو	PROPN
iajs-310	207	23	الشبيه	الشبيه	PROPN
iajs-310	207	24	باالنسولين	باالنسولين	PROPN
iajs-310	207	25	ھو	ھو	AUX
iajs-310	207	26	بروتين	بروتين	VERB
iajs-310	207	27	ينتج	ينتج	ADP
iajs-310	207	28	من	من	INTJ
iajs-310	207	29	الكبد	الكبد	PROPN
iajs-310	208	1	كرد	كرد	INTJ
iajs-310	208	2	فعل	فعل	PROPN
iajs-310	208	3	لھرمون	لھرمون	PROPN
iajs-310	208	4	النمو	النمو	PROPN
iajs-310	208	5	وھو	وھو	PROPN
iajs-310	208	6	المفتاح	المفتاح	ADJ
iajs-310	208	7	المؤ	المؤ	NOUN
iajs-310	208	8	يج	يج	ADP
iajs-310	208	9	الدھني	الدھني	ADJ
iajs-310	208	10	ويعمل	ويعمل	PROPN
iajs-310	208	11	وعالج	وعالج	PROPN
iajs-310	208	12	سوفان	سوفان	NOUN
iajs-310	208	13	المفاصل	المفاصل	VERB
iajs-310	208	14	.	.	PUNCT
iajs-310	209	1	وھناك	وھناك	PROPN
iajs-310	209	2	توازن	توازن	NOUN
iajs-310	209	3	بين	بين	AUX
iajs-310	209	4	ھرمون	ھرمون	NOUN
iajs-310	209	5	النمو	النمو	PROPN
iajs-310	209	6	الشبيه	الشبيه	PROPN
iajs-310	209	7	باالنسولين	باالنسولين	PROPN
iajs-310	209	8	واللبتين	واللبتين	PROPN
iajs-310	209	9	الذي	الذي	PROPN
iajs-310	209	10	ينتج	ينتج	PROPN
iajs-310	209	11	من	من	PROPN
iajs-310	209	12	النس	النس	ADV
iajs-310	209	13	)	)	PUNCT
iajs-310	209	14	عينه	عينه	PROPN
iajs-310	210	1	من	من	DET
iajs-310	210	2	88في	88في	ADJ
iajs-310	210	3	تطور	تطور	NOUN
iajs-310	210	4	مرض	مرض	VERB
iajs-310	210	5	سوفان	سوفان	NOUN
iajs-310	210	6	المفاصل	المفاصل	VERB
iajs-310	210	7	.	.	PUNCT
iajs-310	211	1	وقد	وقد	PROPN
iajs-310	211	2	تضمنت	تضمنت	PROPN
iajs-310	211	3	ھذه	ھذه	INTJ
iajs-310	211	4	الدراسة	الدراسة	PROPN
iajs-310	211	5	(	(	PUNCT
iajs-310	211	6	كمؤشر	كمؤشر	INTJ
iajs-310	211	7	لكتلة	لكتلة	NOUN
iajs-310	212	1	الدھون	الدھون	NOUN
iajs-310	212	2	,	,	PUNCT
iajs-310	212	3	واللبتين	واللبتين	NOUN
iajs-310	212	4	له	له	ADP
iajs-310	212	5	دور	دور	X
iajs-310	212	6	مھم	مھم	NOUN
iajs-310	212	7	)	)	PUNCT
iajs-310	212	8	سنه	سنه	ADV
iajs-310	212	9	,	,	PUNCT
iajs-310	212	10	تم	تم	AUX
iajs-310	212	11	جمع	جمع	PROPN
iajs-310	212	12	العينات	العينات	VERB
iajs-310	212	13	من	من	PRON
iajs-310	212	14	مستشفى	مستشفى	PROPN
iajs-310	212	15	الكاظمية	الكاظمية	PROPN
iajs-310	212	16	التعليمي	التعليمي	VERB
iajs-310	212	17	60	60	NUM
iajs-310	212	18	-	-	SYM
iajs-310	212	19	40النساءكلھم	40النساءكلھم	NUM
iajs-310	213	1	في	في	PRON
iajs-310	213	2	باية	باية	PROPN
iajs-310	213	3	التشخيص	التشخيص	PROPN
iajs-310	213	4	تتراوح	تتراوح	NOUN
iajs-310	213	5	اعماره	اعماره	PROPN
iajs-310	213	6	مبين	مبين	PROPN
iajs-310	213	7	(	(	PUNCT
iajs-310	213	8	جموعة	جموعة	PROPN
iajs-310	213	9	اميع	اميع	PROPN
iajs-310	213	10	وھي	وھي	PROPN
iajs-310	213	11	موالمركز	موالمركز	PROPN
iajs-310	213	12	الوطني	الوطني	PROPN
iajs-310	213	13	لعالج	لعالج	VERB
iajs-310	213	14	وبحوث	وبحوث	VERB
iajs-310	213	15	السكري	السكري	PROPN
iajs-310	213	16	/	/	SYM
iajs-310	213	17	مستشفى	مستشفى	PROPN
iajs-310	213	18	اليرموك	اليرموك	PROPN
iajs-310	213	19	وقد	وقد	PROPN
iajs-310	213	20	قسمت	قسمت	PROPN
iajs-310	214	1	ھذه	ھذه	VERB
iajs-310	214	2	العينات	العينات	VERB
iajs-310	214	3	الى	الى	PROPN
iajs-310	214	4	اربعة	اربعة	PROPN
iajs-310	214	5	مج	مج	ADP
iajs-310	214	6	عينه	عينه	PROPN
iajs-310	214	7	)	)	PUNCT
iajs-310	214	8	,	,	PUNCT
iajs-310	214	9	(	(	PUNCT
iajs-310	214	10	المجموعة	المجموعة	PROPN
iajs-310	214	11	التي	التي	PROPN
iajs-310	214	12	تحمل	تحمل	PROPN
iajs-310	214	13	كال	كال	PROPN
iajs-310	214	14	24عينة	24عينة	NUM
iajs-310	214	15	)	)	PUNCT
iajs-310	214	16	,	,	PUNCT
iajs-310	214	17	(	(	PUNCT
iajs-310	214	18	مجموعة	مجموعة	PROPN
iajs-310	214	19	مرضى	مرضى	PROPN
iajs-310	214	20	سوفان	سوفان	NOUN
iajs-310	214	21	المفاصل	المفاصل	VERB
iajs-310	214	22	20مرضى	20مرضى	NOUN
iajs-310	214	23	السكري	السكري	ADJ
iajs-310	214	24	)	)	PUNCT
iajs-310	214	25	عينه	عينه	PROPN
iajs-310	214	26	وقد	وقد	PROPN
iajs-310	214	27	تم	تم	PROPN
iajs-310	214	28	اجراء	اجراء	NOUN
iajs-310	214	29	الفحوصات	الفحوصات	VERB
iajs-310	214	30	المختبرية	المختبرية	PROPN
iajs-310	214	31	التالية	التالية	NOUN
iajs-310	214	32	:	:	PUNCT
iajs-310	215	1	قياس	قياس	NOUN
iajs-310	215	2	مستوى	مستوى	PROPN
iajs-310	215	3	20عينه	20عينه	NUM
iajs-310	215	4	)	)	PUNCT
iajs-310	216	1	و	و	PRON
iajs-310	216	2	مجموعة	مجموعة	NOUN
iajs-310	216	3	السيطرة	السيطرة	PROPN
iajs-310	216	4	(	(	PUNCT
iajs-310	216	5	24المرضين	24المرضين	NUM
iajs-310	216	6	اب	اب	NOUN
iajs-310	216	7	قيم	قيم	VERB
iajs-310	216	8	مؤش	مؤش	PROPN
iajs-310	216	9	ن	ن	PROPN
iajs-310	216	10	النمو	النمو	PROPN
iajs-310	216	11	الشبيه	الشبيه	PROPN
iajs-310	216	12	باالنسولين	باالنسولين	PROPN
iajs-310	216	13	ومستوى	ومستوى	NOUN
iajs-310	216	14	اللبتين	اللبتين	PROPN
iajs-310	216	15	وايضا	وايضا	PROPN
iajs-310	216	16	حسالكلوكوز	حسالكلوكوز	PROPN
iajs-310	216	17	بالدم	بالدم	NOUN
iajs-310	216	18	و	و	PRON
iajs-310	216	19	قياس	قياس	NOUN
iajs-310	216	20	مستوى	مستوى	PROPN
iajs-310	216	21	الدھون	الدھون	PROPN
iajs-310	216	22	وھرمو	وھرمو	PROPN
iajs-310	216	23	مجاميع	مجاميع	VERB
iajs-310	216	24	اعاله	اعاله	PROPN
iajs-310	216	25	ر	ر	PROPN
iajs-310	216	26	معصد	معصد	ADJ
iajs-310	216	27	البالزما	البالزما	NOUN
iajs-310	216	28	.	.	PUNCT
iajs-310	217	1	في	في	PRON
iajs-310	217	2	ھذه	ھذه	NOUN
iajs-310	217	3	الدراسة	الدراسة	PROPN
iajs-310	217	4	لوحظ	لوحظ	NOUN
iajs-310	217	5	زيادة	زيادة	NOUN
iajs-310	217	6	معنوية	معنوية	NOUN
iajs-310	217	7	في	في	SCONJ
iajs-310	217	8	قيم	قيم	NOUN
iajs-310	217	9	مؤشر	مؤشر	NOUN
iajs-310	217	10	معصد	معصد	NOUN
iajs-310	217	11	البالزما	البالزما	NOUN
iajs-310	217	12	واللبتين	واللبتين	NOUN
iajs-310	217	13	في	في	DET
iajs-310	217	14	كافة	كافة	PROPN
iajs-310	217	15	ال	ال	ADP
iajs-310	217	16	مجاميع	مجاميع	VERB
iajs-310	217	17	اعاله	اعاله	PROPN
iajs-310	217	18	باالنسولين	باالنسولين	NOUN
iajs-310	217	19	في	في	ADP
iajs-310	217	20	نفس	نفس	PROPN
iajs-310	217	21	ال	ال	PROPN
iajs-310	217	22	بالمقارنة	بالمقارنة	NOUN
iajs-310	217	23	مع	مع	PROPN
iajs-310	217	24	مجموعة	مجموعة	PROPN
iajs-310	217	25	السيطرة	السيطرة	PROPN
iajs-310	217	26	.	.	PUNCT
iajs-310	218	1	لكن	لكن	PROPN
iajs-310	218	2	لوحظ	لوحظ	PROPN
iajs-310	218	3	انخفاض	انخفاض	PROPN
iajs-310	218	4	معنوي	معنوي	VERB
iajs-310	218	5	في	في	ADP
iajs-310	218	6	ھرمون	ھرمون	PROPN
iajs-310	218	7	النمو	النمو	PROPN
iajs-310	218	8	الشبيه	الشبيه	PROPN
iajs-310	218	9	ختالل	ختالل	PROPN
iajs-310	218	10	الدھون	الدھون	PROPN
iajs-310	218	11	بالمقارنة	بالمقارنة	PROPN
iajs-310	218	12	مع	مع	PROPN
iajs-310	218	13	مجموعة	مجموعة	PROPN
iajs-310	218	14	السيطرة	السيطرة	PROPN
iajs-310	218	15	.	.	PUNCT
iajs-310	219	1	ومن	ومن	PROPN
iajs-310	219	2	الدراسة	الدراسة	PROPN
iajs-310	219	3	نستنتج	نستنتج	VERB
iajs-310	219	4	ان	ان	ADP
iajs-310	219	5	لمرضى	لمرضى	PROPN
iajs-310	219	6	سوفان	سوفان	NOUN
iajs-310	219	7	المفاصل	المفاصل	VERB
iajs-310	219	8	تاثير	تاثير	VERB
iajs-310	219	9	مباشر	مباشر	NUM
iajs-310	219	10	على	على	NOUN
iajs-310	219	11	زيادة	زيادة	NOUN
iajs-310	220	1	ا	ا	INTJ
iajs-310	221	1	ومستوى	ومستوى	NOUN
iajs-310	221	2	ھرمون	ھرمون	PROPN
iajs-310	221	3	اللبتين	اللبتين	PROPN
iajs-310	221	4	وقيم	وقيم	NOUN
iajs-310	221	5	مؤشر	مؤشر	NOUN
iajs-310	221	6	معصد	معصد	ADJ
iajs-310	221	7	البالزما	البالزما	NOUN
iajs-310	221	8	في	في	ADP
iajs-310	221	9	مرضى	مرضى	PROPN
iajs-310	221	10	السكري	السكري	PROPN
iajs-310	221	11	.	.	PUNCT
iajs-310	222	1	:	:	PUNCT
iajs-310	222	2	سوفان	سوفان	NOUN
iajs-310	222	3	المفاصل	المفاصل	VERB
iajs-310	222	4	,	,	PUNCT
iajs-310	222	5	مؤشر	مؤشر	NOUN
iajs-310	222	6	معصد	معصد	NOUN
iajs-310	222	7	البالزما	البالزما	NOUN
iajs-310	222	8	,	,	PUNCT
iajs-310	222	9	داء	داء	ADV
iajs-310	222	10	السكري	السكري	ADJ
iajs-310	222	11	,	,	PUNCT
iajs-310	222	12	ھرمون	ھرمون	NOUN
iajs-310	222	13	النمو	النمو	PROPN
iajs-310	222	14	الشبيه	الشبيه	PROPN
iajs-310	222	15	باالنسولينالكلمات	باالنسولينالكلمات	VERB
iajs-310	222	16	المفتاحية	المفتاحية	NOUN