id	sid	tid	token	lemma	pos
iajs-3457	1	1	35	35	NUM
iajs-3457	1	2	©	©	PROPN
iajs-3457	1	3	2024	2024	NUM
iajs-3457	1	4	the	the	DET
iajs-3457	1	5	author(s	author(s	NOUN
iajs-3457	1	6	)	)	PUNCT
iajs-3457	1	7	.	.	PUNCT
iajs-3457	2	1	published	publish	VERB
iajs-3457	2	2	by	by	ADP
iajs-3457	2	3	college	college	NOUN
iajs-3457	2	4	of	of	ADP
iajs-3457	2	5	education	education	NOUN
iajs-3457	2	6	for	for	ADP
iajs-3457	2	7	pure	pure	ADJ
iajs-3457	2	8	science	science	NOUN
iajs-3457	2	9	(	(	PUNCT
iajs-3457	2	10	ibn	ibn	PROPN
iajs-3457	2	11	al	al	PROPN
iajs-3457	2	12	-	-	PUNCT
iajs-3457	2	13	haitham	haitham	PROPN
iajs-3457	2	14	)	)	PUNCT
iajs-3457	2	15	,	,	PUNCT
iajs-3457	2	16	university	university	NOUN
iajs-3457	2	17	of	of	ADP
iajs-3457	2	18	baghdad	baghdad	PROPN
iajs-3457	2	19	.	.	PUNCT
iajs-3457	3	1	this	this	PRON
iajs-3457	3	2	is	be	AUX
iajs-3457	3	3	an	an	DET
iajs-3457	3	4	open	open	ADJ
iajs-3457	3	5	-	-	PUNCT
iajs-3457	3	6	access	access	NOUN
iajs-3457	3	7	article	article	NOUN
iajs-3457	3	8	distributed	distribute	VERB
iajs-3457	3	9	under	under	ADP
iajs-3457	3	10	the	the	DET
iajs-3457	3	11	terms	term	NOUN
iajs-3457	3	12	of	of	ADP
iajs-3457	3	13	the	the	DET
iajs-3457	3	14	creative	creative	ADJ
iajs-3457	3	15	commons	common	NOUN
iajs-3457	3	16	attribution	attribution	NOUN
iajs-3457	3	17	4.0	4.0	NUM
iajs-3457	3	18	international	international	ADJ
iajs-3457	3	19	license	license	NOUN
iajs-3457	3	20	assessment	assessment	NOUN
iajs-3457	3	21	of	of	ADP
iajs-3457	3	22	interleukin	interleukin	NOUN
iajs-3457	3	23	1	1	NUM
iajs-3457	3	24	-	-	SYM
iajs-3457	3	25	β	β	NOUN
iajs-3457	3	26	,	,	PUNCT
iajs-3457	3	27	interleukins	interleukin	VERB
iajs-3457	3	28	-6	-6	PUNCT
iajs-3457	3	29	and	and	CCONJ
iajs-3457	3	30	some	some	DET
iajs-3457	3	31	biochemical	biochemical	ADJ
iajs-3457	3	32	parameters	parameter	NOUN
iajs-3457	3	33	in	in	ADP
iajs-3457	3	34	a	a	DET
iajs-3457	3	35	sample	sample	NOUN
iajs-3457	3	36	of	of	ADP
iajs-3457	3	37	iraqi	iraqi	ADJ
iajs-3457	3	38	patients	patient	NOUN
iajs-3457	3	39	with	with	ADP
iajs-3457	3	40	β	β	X
iajs-3457	3	41	–	–	PUNCT
iajs-3457	3	42	thalassemia	thalassemia	NOUN
iajs-3457	3	43	major	major	PROPN
iajs-3457	3	44	ammar	ammar	PROPN
iajs-3457	3	45	j.	j.	PROPN
iajs-3457	3	46	mohammed1	mohammed1	PROPN
iajs-3457	3	47	,	,	PUNCT
iajs-3457	3	48	*	*	PUNCT
iajs-3457	3	49	and	and	CCONJ
iajs-3457	3	50	jabbar	jabbar	PROPN
iajs-3457	3	51	h.	h.	PROPN
iajs-3457	3	52	yenzeel2	yenzeel2	PROPN
iajs-3457	4	1	1,2department	1,2department	NUM
iajs-3457	4	2	of	of	ADP
iajs-3457	4	3	biology	biology	NOUN
iajs-3457	4	4	,	,	PUNCT
iajs-3457	4	5	college	college	NOUN
iajs-3457	4	6	of	of	ADP
iajs-3457	4	7	science	science	NOUN
iajs-3457	4	8	,	,	PUNCT
iajs-3457	4	9	university	university	NOUN
iajs-3457	4	10	of	of	ADP
iajs-3457	4	11	baghdad	baghdad	PROPN
iajs-3457	4	12	,	,	PUNCT
iajs-3457	4	13	baghdad	baghdad	PROPN
iajs-3457	4	14	,	,	PUNCT
iajs-3457	4	15	iraq	iraq	PROPN
iajs-3457	4	16	.	.	PUNCT
iajs-3457	5	1	received	receive	VERB
iajs-3457	5	2	:	:	PUNCT
iajs-3457	5	3	4	4	NUM
iajs-3457	5	4	may	may	PROPN
iajs-3457	5	5	2023	2023	NUM
iajs-3457	5	6	accepted	accept	VERB
iajs-3457	5	7	:	:	PUNCT
iajs-3457	5	8	25	25	NUM
iajs-3457	5	9	june	june	PROPN
iajs-3457	5	10	2023	2023	NUM
iajs-3457	5	11	published	publish	VERB
iajs-3457	5	12	:	:	PUNCT
iajs-3457	5	13	20	20	NUM
iajs-3457	5	14	october	october	NOUN
iajs-3457	5	15	2024	2024	NUM
iajs-3457	5	16	doi.org/10.30526/37.4.3457	doi.org/10.30526/37.4.3457	NOUN
iajs-3457	5	17	abstract	abstract	ADJ
iajs-3457	5	18	sixty	sixty	NUM
iajs-3457	5	19	patients	patient	NOUN
iajs-3457	5	20	(	(	PUNCT
iajs-3457	5	21	male	male	ADJ
iajs-3457	5	22	and	and	CCONJ
iajs-3457	5	23	female	female	NOUN
iajs-3457	5	24	)	)	PUNCT
iajs-3457	5	25	with	with	ADP
iajs-3457	5	26	β	β	NOUN
iajs-3457	5	27	-	-	NOUN
iajs-3457	5	28	thalassemia	thalassemia	VERB
iajs-3457	5	29	major	major	NOUN
iajs-3457	5	30	and	and	CCONJ
iajs-3457	5	31	thirty	thirty	NUM
iajs-3457	5	32	healthy	healthy	ADJ
iajs-3457	5	33	subjects	subject	NOUN
iajs-3457	5	34	were	be	AUX
iajs-3457	5	35	enrolled	enrol	VERB
iajs-3457	5	36	in	in	ADP
iajs-3457	5	37	this	this	DET
iajs-3457	5	38	study	study	NOUN
iajs-3457	5	39	during	during	ADP
iajs-3457	5	40	their	their	PRON
iajs-3457	5	41	attendance	attendance	NOUN
iajs-3457	5	42	at	at	ADP
iajs-3457	5	43	"	"	PUNCT
iajs-3457	5	44	abin	abin	PROPN
iajs-3457	5	45	al	al	PROPN
iajs-3457	5	46	-	-	PUNCT
iajs-3457	5	47	baladi	baladi	PROPN
iajs-3457	5	48	hospital	hospital	NOUN
iajs-3457	5	49	in	in	ADP
iajs-3457	5	50	baghdad	baghdad	PROPN
iajs-3457	5	51	"	"	PUNCT
iajs-3457	5	52	from	from	ADP
iajs-3457	5	53	september	september	PROPN
iajs-3457	5	54	2022	2022	NUM
iajs-3457	5	55	to	to	ADP
iajs-3457	5	56	january	january	PROPN
iajs-3457	5	57	2023	2023	NUM
iajs-3457	5	58	.	.	PUNCT
iajs-3457	6	1	all	all	DET
iajs-3457	6	2	patients	patient	NOUN
iajs-3457	6	3	and	and	CCONJ
iajs-3457	6	4	healthy	healthy	ADJ
iajs-3457	6	5	subjects	subject	NOUN
iajs-3457	6	6	ranged	range	VERB
iajs-3457	6	7	in	in	ADP
iajs-3457	6	8	age	age	NOUN
iajs-3457	6	9	from	from	ADP
iajs-3457	6	10	15	15	NUM
iajs-3457	6	11	to	to	PART
iajs-3457	6	12	30	30	NUM
iajs-3457	6	13	years	year	NOUN
iajs-3457	6	14	,	,	PUNCT
iajs-3457	6	15	and	and	CCONJ
iajs-3457	6	16	we	we	PRON
iajs-3457	6	17	collected	collect	VERB
iajs-3457	6	18	the	the	DET
iajs-3457	6	19	necessary	necessary	ADJ
iajs-3457	6	20	data	datum	NOUN
iajs-3457	6	21	with	with	ADP
iajs-3457	6	22	their	their	PRON
iajs-3457	6	23	consent	consent	NOUN
iajs-3457	6	24	,	,	PUNCT
iajs-3457	6	25	adhering	adhere	VERB
iajs-3457	6	26	to	to	ADP
iajs-3457	6	27	the	the	DET
iajs-3457	6	28	college	college	NOUN
iajs-3457	6	29	of	of	ADP
iajs-3457	6	30	science	science	NOUN
iajs-3457	6	31	's	's	PART
iajs-3457	6	32	ethics	ethic	NOUN
iajs-3457	6	33	(	(	PUNCT
iajs-3457	6	34	csec/0922/0104	csec/0922/0104	NOUN
iajs-3457	6	35	in	in	ADP
iajs-3457	6	36	2022/9/28	2022/9/28	NUM
iajs-3457	6	37	)	)	PUNCT
iajs-3457	6	38	.	.	PUNCT
iajs-3457	7	1	venous	venous	ADJ
iajs-3457	7	2	blood	blood	NOUN
iajs-3457	7	3	was	be	AUX
iajs-3457	7	4	collected	collect	VERB
iajs-3457	7	5	and	and	CCONJ
iajs-3457	7	6	divided	divide	VERB
iajs-3457	7	7	into	into	ADP
iajs-3457	7	8	two	two	NUM
iajs-3457	7	9	parts	part	NOUN
iajs-3457	7	10	:	:	PUNCT
iajs-3457	7	11	the	the	DET
iajs-3457	7	12	first	first	ADJ
iajs-3457	7	13	part	part	NOUN
iajs-3457	7	14	for	for	ADP
iajs-3457	7	15	the	the	DET
iajs-3457	7	16	determination	determination	NOUN
iajs-3457	7	17	of	of	ADP
iajs-3457	7	18	cbc	cbc	NOUN
iajs-3457	7	19	,	,	PUNCT
iajs-3457	7	20	and	and	CCONJ
iajs-3457	7	21	the	the	DET
iajs-3457	7	22	second	second	ADJ
iajs-3457	7	23	part	part	NOUN
iajs-3457	7	24	was	be	AUX
iajs-3457	7	25	allowed	allow	VERB
iajs-3457	7	26	to	to	PART
iajs-3457	7	27	coagulate	coagulate	VERB
iajs-3457	7	28	for	for	ADP
iajs-3457	7	29	serum	serum	NOUN
iajs-3457	7	30	separation	separation	NOUN
iajs-3457	7	31	to	to	PART
iajs-3457	7	32	measure	measure	VERB
iajs-3457	7	33	the	the	DET
iajs-3457	7	34	level	level	NOUN
iajs-3457	7	35	of	of	ADP
iajs-3457	7	36	c	c	NOUN
iajs-3457	7	37	-	-	PUNCT
iajs-3457	7	38	reactive	reactive	ADJ
iajs-3457	7	39	protein	protein	NOUN
iajs-3457	7	40	,	,	PUNCT
iajs-3457	7	41	ferritin	ferritin	ADJ
iajs-3457	7	42	,	,	PUNCT
iajs-3457	7	43	and	and	CCONJ
iajs-3457	7	44	proinflammatory	proinflammatory	ADJ
iajs-3457	7	45	cytokines	cytokine	NOUN
iajs-3457	7	46	like	like	ADP
iajs-3457	7	47	interleukin-1β	interleukin-1β	PRON
iajs-3457	7	48	and	and	CCONJ
iajs-3457	7	49	interleukin-6	interleukin-6	NUM
iajs-3457	7	50	by	by	ADP
iajs-3457	7	51	using	use	VERB
iajs-3457	7	52	the	the	DET
iajs-3457	7	53	elisa	elisa	PROPN
iajs-3457	7	54	kit	kit	PROPN
iajs-3457	7	55	.	.	PUNCT
iajs-3457	8	1	the	the	DET
iajs-3457	8	2	results	result	NOUN
iajs-3457	8	3	showed	show	VERB
iajs-3457	8	4	a	a	DET
iajs-3457	8	5	highly	highly	ADV
iajs-3457	8	6	significant	significant	ADJ
iajs-3457	8	7	(	(	PUNCT
iajs-3457	8	8	p≤0.01	p≤0.01	NOUN
iajs-3457	8	9	)	)	PUNCT
iajs-3457	8	10	decrease	decrease	NOUN
iajs-3457	8	11	in	in	ADP
iajs-3457	8	12	rbc	rbc	PROPN
iajs-3457	8	13	count	count	NOUN
iajs-3457	8	14	and	and	CCONJ
iajs-3457	8	15	hemoglobin	hemoglobin	NOUN
iajs-3457	8	16	(	(	PUNCT
iajs-3457	8	17	3.03	3.03	NUM
iajs-3457	8	18	±0.06	±0.06	ADP
iajs-3457	8	19	106/µl	106/µl	NUM
iajs-3457	8	20	and	and	CCONJ
iajs-3457	8	21	8.01±0.17	8.01±0.17	ADJ
iajs-3457	8	22	hg	hg	PROPN
iajs-3457	8	23	/	/	SYM
iajs-3457	8	24	dl	dl	PROPN
iajs-3457	8	25	)	)	PUNCT
iajs-3457	8	26	respectively	respectively	ADV
iajs-3457	8	27	in	in	ADP
iajs-3457	8	28	β	β	NOUN
iajs-3457	8	29	-	-	ADJ
iajs-3457	8	30	thalassemia	thalassemia	NOUN
iajs-3457	8	31	patients	patient	NOUN
iajs-3457	8	32	in	in	ADP
iajs-3457	8	33	compare	compare	NOUN
iajs-3457	8	34	with	with	ADP
iajs-3457	8	35	control	control	NOUN
iajs-3457	8	36	group	group	NOUN
iajs-3457	8	37	(	(	PUNCT
iajs-3457	8	38	4.77±0.07	4.77±0.07	PROPN
iajs-3457	8	39	106/µl	106/µl	NUM
iajs-3457	8	40	and	and	CCONJ
iajs-3457	8	41	14.06	14.06	NUM
iajs-3457	8	42	±0.24	±0.24	NOUN
iajs-3457	8	43	hg	hg	PROPN
iajs-3457	8	44	/	/	SYM
iajs-3457	8	45	dl	dl	PROPN
iajs-3457	8	46	)	)	PUNCT
iajs-3457	8	47	respectively	respectively	ADV
iajs-3457	8	48	,	,	PUNCT
iajs-3457	8	49	while	while	SCONJ
iajs-3457	8	50	there	there	PRON
iajs-3457	8	51	was	be	VERB
iajs-3457	8	52	a	a	DET
iajs-3457	8	53	highly	highly	ADV
iajs-3457	8	54	significant	significant	ADJ
iajs-3457	8	55	(	(	PUNCT
iajs-3457	8	56	p≤0.01	p≤0.01	NOUN
iajs-3457	8	57	)	)	PUNCT
iajs-3457	8	58	increase	increase	NOUN
iajs-3457	8	59	in	in	ADP
iajs-3457	8	60	the	the	DET
iajs-3457	8	61	platelets	platelet	NOUN
iajs-3457	8	62	count	count	NOUN
iajs-3457	8	63	(	(	PUNCT
iajs-3457	8	64	384.59	384.59	NUM
iajs-3457	8	65	±21.67	±21.67	NOUN
iajs-3457	8	66	10	10	NUM
iajs-3457	8	67	^	^	SYM
iajs-3457	8	68	3/µl	3/µl	NUM
iajs-3457	8	69	)	)	PUNCT
iajs-3457	8	70	in	in	ADP
iajs-3457	8	71	patients	patient	NOUN
iajs-3457	8	72	compared	compare	VERB
iajs-3457	8	73	with	with	ADP
iajs-3457	8	74	control	control	NOUN
iajs-3457	8	75	(	(	PUNCT
iajs-3457	8	76	224.06	224.06	NUM
iajs-3457	9	1	±6.23	±6.23	NUM
iajs-3457	9	2	10	10	NUM
iajs-3457	9	3	^	^	SYM
iajs-3457	9	4	3/µl	3/µl	NUM
iajs-3457	9	5	)	)	PUNCT
iajs-3457	9	6	;	;	PUNCT
iajs-3457	9	7	furthermore	furthermore	ADV
iajs-3457	9	8	,	,	PUNCT
iajs-3457	9	9	ferritin	ferritin	ADJ
iajs-3457	9	10	and	and	CCONJ
iajs-3457	9	11	crp	crp	PROPN
iajs-3457	9	12	showed	show	VERB
iajs-3457	9	13	highly	highly	ADV
iajs-3457	9	14	significant	significant	ADJ
iajs-3457	9	15	(	(	PUNCT
iajs-3457	9	16	p≤0.01	p≤0.01	NOUN
iajs-3457	9	17	)	)	PUNCT
iajs-3457	9	18	increase	increase	NOUN
iajs-3457	9	19	(	(	PUNCT
iajs-3457	9	20	4910.15±202.67	4910.15±202.67	PROPN
iajs-3457	9	21	ng	ng	PROPN
iajs-3457	9	22	/	/	SYM
iajs-3457	9	23	ml	ml	PROPN
iajs-3457	9	24	,	,	PUNCT
iajs-3457	9	25	and	and	CCONJ
iajs-3457	9	26	3.02	3.02	NUM
iajs-3457	9	27	±0.08	±0.08	PROPN
iajs-3457	9	28	µg	µg	ADV
iajs-3457	9	29	/	/	SYM
iajs-3457	9	30	ml	ml	NOUN
iajs-3457	9	31	)	)	PUNCT
iajs-3457	9	32	respectively	respectively	ADV
iajs-3457	9	33	in	in	ADP
iajs-3457	9	34	patients	patient	NOUN
iajs-3457	9	35	compared	compare	VERB
iajs-3457	9	36	with	with	ADP
iajs-3457	9	37	control	control	NOUN
iajs-3457	9	38	(	(	PUNCT
iajs-3457	9	39	284.91±16.78	284.91±16.78	PROPN
iajs-3457	9	40	ng	ng	PROPN
iajs-3457	9	41	/	/	SYM
iajs-3457	9	42	ml	ml	PROPN
iajs-3457	9	43	,	,	PUNCT
iajs-3457	9	44	and	and	CCONJ
iajs-3457	9	45	1.178	1.178	NUM
iajs-3457	9	46	±0.03	±0.03	PROPN
iajs-3457	9	47	µg	µg	ADV
iajs-3457	9	48	/	/	SYM
iajs-3457	9	49	ml	ml	NOUN
iajs-3457	9	50	)	)	PUNCT
iajs-3457	9	51	respectively	respectively	ADV
iajs-3457	9	52	.	.	PUNCT
iajs-3457	10	1	also	also	ADV
iajs-3457	10	2	,	,	PUNCT
iajs-3457	10	3	there	there	PRON
iajs-3457	10	4	was	be	VERB
iajs-3457	10	5	a	a	DET
iajs-3457	10	6	highly	highly	ADV
iajs-3457	10	7	significant	significant	ADJ
iajs-3457	10	8	(	(	PUNCT
iajs-3457	10	9	p≤0.01	p≤0.01	NOUN
iajs-3457	10	10	)	)	PUNCT
iajs-3457	10	11	increase	increase	NOUN
iajs-3457	10	12	in	in	ADP
iajs-3457	10	13	il-1β	il-1β	PROPN
iajs-3457	10	14	and	and	CCONJ
iajs-3457	10	15	il-6	il-6	NOUN
iajs-3457	10	16	,	,	PUNCT
iajs-3457	10	17	which	which	PRON
iajs-3457	10	18	were	be	AUX
iajs-3457	10	19	284.19	284.19	NUM
iajs-3457	10	20	±4.29	±4.29	NOUN
iajs-3457	10	21	pg	pg	NOUN
iajs-3457	10	22	/	/	SYM
iajs-3457	10	23	ml	ml	NOUN
iajs-3457	10	24	and	and	CCONJ
iajs-3457	10	25	27.92±0.97	27.92±0.97	NUM
iajs-3457	10	26	pg	pg	PROPN
iajs-3457	10	27	/	/	SYM
iajs-3457	10	28	ml	ml	NOUN
iajs-3457	10	29	,	,	PUNCT
iajs-3457	10	30	respectively	respectively	ADV
iajs-3457	10	31	,	,	PUNCT
iajs-3457	10	32	in	in	ADP
iajs-3457	10	33	patients	patient	NOUN
iajs-3457	10	34	in	in	ADP
iajs-3457	10	35	comparison	comparison	NOUN
iajs-3457	10	36	with	with	ADP
iajs-3457	10	37	control	control	NOUN
iajs-3457	10	38	(	(	PUNCT
iajs-3457	10	39	142.09	142.09	NUM
iajs-3457	10	40	±0.70	±0.70	PROPN
iajs-3457	10	41	pg	pg	PROPN
iajs-3457	10	42	/	/	SYM
iajs-3457	10	43	ml	ml	NOUN
iajs-3457	10	44	and	and	CCONJ
iajs-3457	10	45	11.43	11.43	NUM
iajs-3457	10	46	±0.32	±0.32	VERB
iajs-3457	10	47	pg	pg	NOUN
iajs-3457	10	48	/	/	SYM
iajs-3457	10	49	ml	ml	NOUN
iajs-3457	10	50	)	)	PUNCT
iajs-3457	10	51	,	,	PUNCT
iajs-3457	10	52	respectively	respectively	ADV
iajs-3457	10	53	.	.	PUNCT
iajs-3457	11	1	from	from	ADP
iajs-3457	11	2	the	the	DET
iajs-3457	11	3	above	above	ADJ
iajs-3457	11	4	findings	finding	NOUN
iajs-3457	11	5	,	,	PUNCT
iajs-3457	11	6	it	it	PRON
iajs-3457	11	7	can	can	AUX
iajs-3457	11	8	be	be	AUX
iajs-3457	11	9	concluded	conclude	VERB
iajs-3457	11	10	that	that	SCONJ
iajs-3457	11	11	proinflammatory	proinflammatory	ADJ
iajs-3457	11	12	cytokines	cytokine	NOUN
iajs-3457	11	13	have	have	VERB
iajs-3457	11	14	a	a	DET
iajs-3457	11	15	significant	significant	ADJ
iajs-3457	11	16	impact	impact	NOUN
iajs-3457	11	17	on	on	ADP
iajs-3457	11	18	the	the	DET
iajs-3457	11	19	progression	progression	NOUN
iajs-3457	11	20	and	and	CCONJ
iajs-3457	11	21	pathology	pathology	NOUN
iajs-3457	11	22	of	of	ADP
iajs-3457	11	23	the	the	DET
iajs-3457	11	24	disease	disease	NOUN
iajs-3457	11	25	.	.	PUNCT
iajs-3457	12	1	keyword	keyword	NOUN
iajs-3457	12	2	:	:	PUNCT
iajs-3457	12	3	β	β	X
iajs-3457	12	4	-	-	PUNCT
iajs-3457	12	5	thalassemia	thalassemia	ADJ
iajs-3457	12	6	major	major	ADJ
iajs-3457	12	7	,	,	PUNCT
iajs-3457	12	8	ferritin	ferritin	ADJ
iajs-3457	12	9	,	,	PUNCT
iajs-3457	12	10	interleukin	interleukin	NOUN
iajs-3457	12	11	-1β	-1β	NOUN
iajs-3457	12	12	,	,	PUNCT
iajs-3457	12	13	interleukin-6	interleukin-6	X
iajs-3457	12	14	.	.	NOUN
iajs-3457	12	15	1	1	NUM
iajs-3457	12	16	.	.	X
iajs-3457	12	17	introduction	introduction	NOUN
iajs-3457	12	18	thalassemia	thalassemia	NOUN
iajs-3457	12	19	is	be	AUX
iajs-3457	12	20	associated	associate	VERB
iajs-3457	12	21	with	with	ADP
iajs-3457	12	22	the	the	DET
iajs-3457	12	23	majority	majority	NOUN
iajs-3457	12	24	of	of	ADP
iajs-3457	12	25	monogenic	monogenic	ADJ
iajs-3457	12	26	illnesses	illness	NOUN
iajs-3457	12	27	,	,	PUNCT
iajs-3457	12	28	which	which	PRON
iajs-3457	12	29	are	be	AUX
iajs-3457	12	30	hereditary	hereditary	ADJ
iajs-3457	12	31	hemoglobinopathies	hemoglobinopathy	NOUN
iajs-3457	12	32	that	that	PRON
iajs-3457	12	33	are	be	AUX
iajs-3457	12	34	characterized	characterize	VERB
iajs-3457	12	35	by	by	ADP
iajs-3457	12	36	inadequate	inadequate	ADJ
iajs-3457	12	37	erythropoiesis	erythropoiesis	NOUN
iajs-3457	12	38	,	,	PUNCT
iajs-3457	12	39	hemolysis	hemolysis	NOUN
iajs-3457	12	40	,	,	PUNCT
iajs-3457	12	41	and	and	CCONJ
iajs-3457	12	42	accelerated	accelerate	VERB
iajs-3457	12	43	red	red	ADJ
iajs-3457	12	44	blood	blood	NOUN
iajs-3457	12	45	cell	cell	NOUN
iajs-3457	12	46	turnover	turnover	NOUN
iajs-3457	12	47	.	.	PUNCT
iajs-3457	13	1	the	the	DET
iajs-3457	13	2	genetic	genetic	ADJ
iajs-3457	13	3	disorder	disorder	NOUN
iajs-3457	13	4	known	know	VERB
iajs-3457	13	5	as	as	ADP
iajs-3457	13	6	thalassemia	thalassemia	NOUN
iajs-3457	13	7	is	be	AUX
iajs-3457	13	8	believed	believe	VERB
iajs-3457	13	9	to	to	PART
iajs-3457	13	10	decrease	decrease	VERB
iajs-3457	13	11	the	the	DET
iajs-3457	13	12	production	production	NOUN
iajs-3457	13	13	of	of	ADP
iajs-3457	13	14	the	the	DET
iajs-3457	13	15	alpha	alpha	NOUN
iajs-3457	13	16	or	or	CCONJ
iajs-3457	13	17	beta	beta	ADJ
iajs-3457	13	18	chains	chain	NOUN
iajs-3457	13	19	of	of	ADP
iajs-3457	13	20	hemoglobin	hemoglobin	NOUN
iajs-3457	13	21	[	[	X
iajs-3457	13	22	1	1	NUM
iajs-3457	13	23	]	]	PUNCT
iajs-3457	13	24	.	.	PUNCT
iajs-3457	14	1	if	if	SCONJ
iajs-3457	14	2	the	the	DET
iajs-3457	14	3	body	body	NOUN
iajs-3457	14	4	fails	fail	VERB
iajs-3457	14	5	to	to	PART
iajs-3457	14	6	produce	produce	VERB
iajs-3457	14	7	either	either	PRON
iajs-3457	14	8	of	of	ADP
iajs-3457	14	9	these	these	DET
iajs-3457	14	10	two	two	NUM
iajs-3457	14	11	proteins	protein	NOUN
iajs-3457	14	12	sufficiently	sufficiently	ADV
iajs-3457	14	13	,	,	PUNCT
iajs-3457	14	14	it	it	PRON
iajs-3457	14	15	disrupts	disrupt	VERB
iajs-3457	14	16	the	the	DET
iajs-3457	14	17	proper	proper	ADJ
iajs-3457	14	18	formation	formation	NOUN
iajs-3457	14	19	of	of	ADP
iajs-3457	14	20	red	red	ADJ
iajs-3457	14	21	blood	blood	NOUN
iajs-3457	14	22	cells	cell	NOUN
iajs-3457	14	23	,	,	PUNCT
iajs-3457	14	24	preventing	prevent	VERB
iajs-3457	14	25	them	they	PRON
iajs-3457	14	26	from	from	ADP
iajs-3457	14	27	carrying	carry	VERB
iajs-3457	14	28	sufficient	sufficient	ADJ
iajs-3457	14	29	oxygen	oxygen	NOUN
iajs-3457	14	30	;	;	PUNCT
iajs-3457	14	31	this	this	PRON
iajs-3457	14	32	leads	lead	VERB
iajs-3457	14	33	to	to	ADP
iajs-3457	14	34	anemia	anemia	NOUN
iajs-3457	14	35	that	that	PRON
iajs-3457	14	36	persists	persist	VERB
iajs-3457	14	37	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
iajs-3457	14	38	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
iajs-3457	14	39	https://orcid.org/0009-0009-6407-9399	https://orcid.org/0009-0009-6407-9399	PROPN
iajs-3457	14	40	mailto:ammarjaffar796@gmail.com	mailto:ammarjaffar796@gmail.com	PROPN
iajs-3457	14	41	https://orcid.org/0000-0002-0956-7703	https://orcid.org/0000-0002-0956-7703	PROPN
iajs-3457	14	42	mailto:jabbar.yenzeel@sc.uobaghdad.edu.iq	mailto:jabbar.yenzeel@sc.uobaghdad.edu.iq	PROPN
iajs-3457	14	43	ihjpas	ihjpas	PROPN
iajs-3457	14	44	.	.	PUNCT
iajs-3457	15	1	2024	2024	NUM
iajs-3457	15	2	,	,	PUNCT
iajs-3457	15	3	37(4	37(4	NUM
iajs-3457	15	4	)	)	PUNCT
iajs-3457	15	5	36	36	NUM
iajs-3457	15	6	throughout	throughout	ADP
iajs-3457	15	7	a	a	DET
iajs-3457	15	8	person	person	NOUN
iajs-3457	15	9	's	's	PART
iajs-3457	15	10	life	life	NOUN
iajs-3457	15	11	,	,	PUNCT
iajs-3457	15	12	starting	start	VERB
iajs-3457	15	13	in	in	ADP
iajs-3457	15	14	early	early	ADJ
iajs-3457	15	15	childhood	childhood	NOUN
iajs-3457	15	16	[	[	X
iajs-3457	15	17	2	2	NUM
iajs-3457	15	18	]	]	PUNCT
iajs-3457	15	19	.	.	PUNCT
iajs-3457	16	1	more	more	ADJ
iajs-3457	16	2	than	than	ADP
iajs-3457	16	3	150	150	NUM
iajs-3457	16	4	distinct	distinct	ADJ
iajs-3457	16	5	mutations	mutation	NOUN
iajs-3457	16	6	on	on	ADP
iajs-3457	16	7	chromosomes	chromosome	NOUN
iajs-3457	16	8	11	11	NUM
iajs-3457	16	9	and	and	CCONJ
iajs-3457	16	10	16	16	NUM
iajs-3457	16	11	have	have	AUX
iajs-3457	16	12	been	be	AUX
iajs-3457	16	13	discovered	discover	VERB
iajs-3457	16	14	to	to	PART
iajs-3457	16	15	be	be	AUX
iajs-3457	16	16	responsible	responsible	ADJ
iajs-3457	16	17	for	for	ADP
iajs-3457	16	18	the	the	DET
iajs-3457	16	19	cases	case	NOUN
iajs-3457	16	20	of	of	ADP
iajs-3457	16	21	αand	αand	ADV
iajs-3457	16	22	βthalassemia	βthalassemia	ADJ
iajs-3457	16	23	,	,	PUNCT
iajs-3457	16	24	respectively	respectively	ADV
iajs-3457	16	25	.	.	PUNCT
iajs-3457	17	1	because	because	SCONJ
iajs-3457	17	2	people	people	NOUN
iajs-3457	17	3	with	with	ADP
iajs-3457	17	4	thalassemia	thalassemia	NOUN
iajs-3457	17	5	do	do	AUX
iajs-3457	17	6	n't	not	PART
iajs-3457	17	7	make	make	VERB
iajs-3457	17	8	enough	enough	ADJ
iajs-3457	17	9	β	β	NOUN
iajs-3457	17	10	-	-	NOUN
iajs-3457	17	11	globulin	globulin	NOUN
iajs-3457	17	12	,	,	PUNCT
iajs-3457	17	13	erythrocyte	erythrocyte	NOUN
iajs-3457	17	14	precursors	precursor	NOUN
iajs-3457	17	15	make	make	VERB
iajs-3457	17	16	too	too	ADV
iajs-3457	17	17	many	many	ADJ
iajs-3457	17	18	α	α	ADJ
iajs-3457	17	19	-	-	ADJ
iajs-3457	17	20	globulin	globulin	NOUN
iajs-3457	17	21	chains	chain	NOUN
iajs-3457	17	22	.	.	PUNCT
iajs-3457	18	1	this	this	PRON
iajs-3457	18	2	hurts	hurt	VERB
iajs-3457	18	3	the	the	DET
iajs-3457	18	4	bone	bone	NOUN
iajs-3457	18	5	marrow	marrow	NOUN
iajs-3457	18	6	and	and	CCONJ
iajs-3457	18	7	the	the	DET
iajs-3457	18	8	blood	blood	NOUN
iajs-3457	18	9	flow	flow	NOUN
iajs-3457	18	10	to	to	ADP
iajs-3457	18	11	the	the	DET
iajs-3457	18	12	body	body	NOUN
iajs-3457	18	13	's	's	PART
iajs-3457	18	14	surfaces	surface	NOUN
iajs-3457	18	15	[	[	X
iajs-3457	18	16	3	3	NUM
iajs-3457	18	17	]	]	PUNCT
iajs-3457	18	18	.	.	PUNCT
iajs-3457	19	1	beta	beta	NOUN
iajs-3457	19	2	-	-	PUNCT
iajs-3457	19	3	thalassemia	thalassemia	NOUN
iajs-3457	19	4	major	major	NOUN
iajs-3457	19	5	is	be	AUX
iajs-3457	19	6	a	a	DET
iajs-3457	19	7	genetic	genetic	ADJ
iajs-3457	19	8	hemoglobin	hemoglobin	NOUN
iajs-3457	19	9	synthesis	synthesis	NOUN
iajs-3457	19	10	disease	disease	NOUN
iajs-3457	19	11	that	that	PRON
iajs-3457	19	12	causes	cause	VERB
iajs-3457	19	13	severe	severe	ADJ
iajs-3457	19	14	anemia	anemia	NOUN
iajs-3457	19	15	in	in	ADP
iajs-3457	19	16	homozygous	homozygous	ADJ
iajs-3457	19	17	individuals	individual	NOUN
iajs-3457	19	18	.	.	PUNCT
iajs-3457	20	1	the	the	DET
iajs-3457	20	2	homozygous	homozygous	ADJ
iajs-3457	20	3	illness	illness	NOUN
iajs-3457	20	4	was	be	AUX
iajs-3457	20	5	previously	previously	ADV
iajs-3457	20	6	known	know	VERB
iajs-3457	20	7	to	to	PART
iajs-3457	20	8	be	be	AUX
iajs-3457	20	9	prevalent	prevalent	ADJ
iajs-3457	20	10	in	in	ADP
iajs-3457	20	11	the	the	DET
iajs-3457	20	12	middle	middle	PROPN
iajs-3457	20	13	east	east	PROPN
iajs-3457	20	14	and	and	CCONJ
iajs-3457	20	15	mediterranean	mediterranean	PROPN
iajs-3457	20	16	nations	nation	NOUN
iajs-3457	20	17	,	,	PUNCT
iajs-3457	20	18	but	but	CCONJ
iajs-3457	20	19	migration	migration	NOUN
iajs-3457	20	20	has	have	AUX
iajs-3457	20	21	altered	alter	VERB
iajs-3457	20	22	its	its	PRON
iajs-3457	20	23	geographic	geographic	ADJ
iajs-3457	20	24	distribution	distribution	NOUN
iajs-3457	20	25	and	and	CCONJ
iajs-3457	20	26	made	make	VERB
iajs-3457	20	27	it	it	PRON
iajs-3457	20	28	a	a	DET
iajs-3457	20	29	global	global	ADJ
iajs-3457	20	30	health	health	NOUN
iajs-3457	20	31	issue	issue	NOUN
iajs-3457	20	32	[	[	X
iajs-3457	20	33	4	4	NUM
iajs-3457	20	34	]	]	PUNCT
iajs-3457	20	35	.	.	PUNCT
iajs-3457	21	1	the	the	DET
iajs-3457	21	2	disease	disease	NOUN
iajs-3457	21	3	is	be	AUX
iajs-3457	21	4	associated	associate	VERB
iajs-3457	21	5	with	with	ADP
iajs-3457	21	6	toxemia	toxemia	NOUN
iajs-3457	21	7	,	,	PUNCT
iajs-3457	21	8	increased	increase	VERB
iajs-3457	21	9	bone	bone	NOUN
iajs-3457	21	10	marrow	marrow	NOUN
iajs-3457	21	11	space	space	NOUN
iajs-3457	21	12	,	,	PUNCT
iajs-3457	21	13	splenomegaly	splenomegaly	ADJ
iajs-3457	21	14	,	,	PUNCT
iajs-3457	21	15	extreme	extreme	ADJ
iajs-3457	21	16	anemia	anemia	NOUN
iajs-3457	21	17	,	,	PUNCT
iajs-3457	21	18	jaundice	jaundice	NOUN
iajs-3457	21	19	,	,	PUNCT
iajs-3457	21	20	and	and	CCONJ
iajs-3457	21	21	cardiomegaly	cardiomegaly	NOUN
iajs-3457	21	22	.	.	PUNCT
iajs-3457	22	1	these	these	DET
iajs-3457	22	2	signs	sign	NOUN
iajs-3457	22	3	start	start	VERB
iajs-3457	22	4	to	to	PART
iajs-3457	22	5	show	show	VERB
iajs-3457	22	6	between	between	ADP
iajs-3457	22	7	two	two	NUM
iajs-3457	22	8	and	and	CCONJ
iajs-3457	22	9	four	four	NUM
iajs-3457	22	10	months	month	NOUN
iajs-3457	22	11	of	of	ADP
iajs-3457	22	12	age	age	NOUN
iajs-3457	22	13	[	[	X
iajs-3457	22	14	5	5	NUM
iajs-3457	22	15	]	]	PUNCT
iajs-3457	22	16	.	.	PUNCT
iajs-3457	23	1	it	it	PRON
iajs-3457	23	2	comes	come	VERB
iajs-3457	23	3	in	in	ADP
iajs-3457	23	4	three	three	NUM
iajs-3457	23	5	main	main	ADJ
iajs-3457	23	6	forms	form	NOUN
iajs-3457	23	7	:	:	PUNCT
iajs-3457	23	8	"	"	PUNCT
iajs-3457	23	9	β	β	X
iajs-3457	23	10	-	-	PUNCT
iajs-3457	23	11	thalassemia	thalassemia	ADJ
iajs-3457	23	12	major	major	NOUN
iajs-3457	23	13	(	(	PUNCT
iajs-3457	23	14	tm	tm	NOUN
iajs-3457	23	15	)	)	PUNCT
iajs-3457	23	16	"	"	PUNCT
iajs-3457	23	17	,	,	PUNCT
iajs-3457	23	18	also	also	ADV
iajs-3457	23	19	called	call	VERB
iajs-3457	23	20	"	"	PUNCT
iajs-3457	23	21	cooley	cooley	PROPN
iajs-3457	23	22	's	's	PART
iajs-3457	23	23	anemia	anemia	NOUN
iajs-3457	23	24	"	"	PUNCT
iajs-3457	23	25	and	and	CCONJ
iajs-3457	23	26	"	"	PUNCT
iajs-3457	23	27	mediterranean	mediterranean	ADJ
iajs-3457	23	28	anemia	anemia	NOUN
iajs-3457	23	29	,	,	PUNCT
iajs-3457	23	30	"	"	PUNCT
iajs-3457	23	31	"	"	PUNCT
iajs-3457	23	32	βthalassemia	βthalassemia	ADJ
iajs-3457	23	33	intermediate	intermediate	ADJ
iajs-3457	23	34	(	(	PUNCT
iajs-3457	23	35	ti	ti	NOUN
iajs-3457	23	36	)	)	PUNCT
iajs-3457	23	37	"	"	PUNCT
iajs-3457	23	38	,	,	PUNCT
iajs-3457	23	39	and	and	CCONJ
iajs-3457	23	40	"	"	PUNCT
iajs-3457	23	41	β	β	X
iajs-3457	23	42	-	-	PUNCT
iajs-3457	23	43	thalassemia	thalassemia	ADJ
iajs-3457	23	44	minor	minor	ADJ
iajs-3457	23	45	"	"	PUNCT
iajs-3457	23	46	,	,	PUNCT
iajs-3457	23	47	also	also	ADV
iajs-3457	23	48	called	call	VERB
iajs-3457	23	49	"	"	PUNCT
iajs-3457	23	50	heterozygous	heterozygous	ADJ
iajs-3457	23	51	βthalassemia	βthalassemia	NOUN
iajs-3457	23	52	,	,	PUNCT
iajs-3457	23	53	"	"	PUNCT
iajs-3457	23	54	"	"	PUNCT
iajs-3457	23	55	β	β	X
iajs-3457	23	56	-	-	PUNCT
iajs-3457	23	57	thalassemia	thalassemia	NOUN
iajs-3457	23	58	carrier	carrier	NOUN
iajs-3457	23	59	,	,	PUNCT
iajs-3457	23	60	"	"	PUNCT
iajs-3457	23	61	and	and	CCONJ
iajs-3457	23	62	"	"	PUNCT
iajs-3457	23	63	β	β	NOUN
iajs-3457	23	64	-	-	PUNCT
iajs-3457	23	65	thalassemia	thalassemia	NOUN
iajs-3457	23	66	trait	trait	NOUN
iajs-3457	23	67	"	"	PUNCT
iajs-3457	24	1	[	[	X
iajs-3457	24	2	6	6	NUM
iajs-3457	24	3	]	]	PUNCT
iajs-3457	24	4	.	.	PUNCT
iajs-3457	25	1	beta	beta	NOUN
iajs-3457	25	2	-	-	PUNCT
iajs-3457	25	3	thalassemia	thalassemia	NOUN
iajs-3457	25	4	results	result	NOUN
iajs-3457	25	5	from	from	ADP
iajs-3457	25	6	a	a	DET
iajs-3457	25	7	relative	relative	ADJ
iajs-3457	25	8	abundance	abundance	NOUN
iajs-3457	25	9	of	of	ADP
iajs-3457	25	10	α	α	PROPN
iajs-3457	25	11	-	-	PUNCT
iajs-3457	25	12	chains	chain	NOUN
iajs-3457	25	13	caused	cause	VERB
iajs-3457	25	14	by	by	ADP
iajs-3457	25	15	decreased	decrease	VERB
iajs-3457	25	16	β	β	ADJ
iajs-3457	25	17	-	-	ADJ
iajs-3457	25	18	globin	globin	ADJ
iajs-3457	25	19	chain	chain	NOUN
iajs-3457	25	20	formation	formation	NOUN
iajs-3457	25	21	.	.	PUNCT
iajs-3457	26	1	the	the	DET
iajs-3457	26	2	damage	damage	NOUN
iajs-3457	26	3	that	that	PRON
iajs-3457	26	4	free	free	ADJ
iajs-3457	26	5	α	α	PROPN
iajs-3457	26	6	-	-	NOUN
iajs-3457	26	7	globin	globin	NOUN
iajs-3457	26	8	does	do	VERB
iajs-3457	26	9	to	to	ADP
iajs-3457	26	10	red	red	ADJ
iajs-3457	26	11	blood	blood	NOUN
iajs-3457	26	12	cell	cell	NOUN
iajs-3457	26	13	membranes	membrane	NOUN
iajs-3457	26	14	causes	cause	VERB
iajs-3457	26	15	reactive	reactive	ADJ
iajs-3457	26	16	oxygen	oxygen	NOUN
iajs-3457	26	17	species	specie	NOUN
iajs-3457	26	18	to	to	PART
iajs-3457	26	19	form	form	VERB
iajs-3457	26	20	precipitate	precipitate	NOUN
iajs-3457	26	21	,	,	PUNCT
iajs-3457	26	22	which	which	PRON
iajs-3457	26	23	leads	lead	VERB
iajs-3457	26	24	to	to	ADP
iajs-3457	26	25	hemolysis	hemolysis	NOUN
iajs-3457	26	26	and	and	CCONJ
iajs-3457	26	27	abnormal	abnormal	ADJ
iajs-3457	26	28	erythroid	erythroid	ADJ
iajs-3457	26	29	maturation	maturation	NOUN
iajs-3457	26	30	[	[	X
iajs-3457	26	31	7	7	NUM
iajs-3457	26	32	]	]	PUNCT
iajs-3457	26	33	.	.	PUNCT
iajs-3457	27	1	"	"	PUNCT
iajs-3457	27	2	beta	beta	NOUN
iajs-3457	27	3	-	-	PUNCT
iajs-3457	27	4	thalassemia	thalassemia	NOUN
iajs-3457	27	5	major	major	NOUN
iajs-3457	27	6	,	,	PUNCT
iajs-3457	27	7	also	also	ADV
iajs-3457	27	8	called	call	VERB
iajs-3457	27	9	cooley	cooley	PROPN
iajs-3457	27	10	's	's	PART
iajs-3457	27	11	anemia	anemia	NOUN
iajs-3457	27	12	,	,	PUNCT
iajs-3457	27	13	is	be	AUX
iajs-3457	27	14	a	a	DET
iajs-3457	27	15	very	very	ADV
iajs-3457	27	16	bad	bad	ADJ
iajs-3457	27	17	type	type	NOUN
iajs-3457	27	18	of	of	ADP
iajs-3457	27	19	thalassemia	thalassemia	NOUN
iajs-3457	27	20	that	that	PRON
iajs-3457	27	21	can	can	AUX
iajs-3457	27	22	happen	happen	VERB
iajs-3457	27	23	to	to	ADP
iajs-3457	27	24	people	people	NOUN
iajs-3457	27	25	who	who	PRON
iajs-3457	27	26	are	be	AUX
iajs-3457	27	27	homozygous	homozygous	ADJ
iajs-3457	27	28	(	(	PUNCT
iajs-3457	27	29	²+/²0	²+/²0	ADJ
iajs-3457	27	30	,	,	PUNCT
iajs-3457	27	31	²0/²0	²0/²0	NUM
iajs-3457	27	32	)	)	PUNCT
iajs-3457	27	33	or	or	CCONJ
iajs-3457	27	34	compound	compound	VERB
iajs-3457	27	35	heterozygous	heterozygous	ADJ
iajs-3457	27	36	(	(	PUNCT
iajs-3457	27	37	²+/²+	²+/²+	PROPN
iajs-3457	27	38	)	)	PUNCT
iajs-3457	27	39	for	for	ADP
iajs-3457	27	40	much	much	ADV
iajs-3457	27	41	worse	bad	ADJ
iajs-3457	27	42	mutations	mutation	NOUN
iajs-3457	27	43	in	in	ADP
iajs-3457	27	44	the	the	DET
iajs-3457	27	45	chain	chain	NOUN
iajs-3457	27	46	"	"	PUNCT
iajs-3457	27	47	[	[	X
iajs-3457	27	48	8	8	NUM
iajs-3457	27	49	]	]	PUNCT
iajs-3457	27	50	.	.	PUNCT
iajs-3457	28	1	the	the	DET
iajs-3457	28	2	majority	majority	NOUN
iajs-3457	28	3	of	of	ADP
iajs-3457	28	4	patients	patient	NOUN
iajs-3457	28	5	receive	receive	VERB
iajs-3457	28	6	recurrent	recurrent	ADJ
iajs-3457	28	7	blood	blood	NOUN
iajs-3457	28	8	transfusions	transfusion	NOUN
iajs-3457	28	9	instead	instead	ADV
iajs-3457	28	10	of	of	ADP
iajs-3457	28	11	stem	stem	NOUN
iajs-3457	28	12	cell	cell	NOUN
iajs-3457	28	13	transplantation	transplantation	NOUN
iajs-3457	28	14	,	,	PUNCT
iajs-3457	28	15	which	which	PRON
iajs-3457	28	16	is	be	AUX
iajs-3457	28	17	an	an	DET
iajs-3457	28	18	effective	effective	ADJ
iajs-3457	28	19	but	but	CCONJ
iajs-3457	28	20	not	not	PART
iajs-3457	28	21	always	always	ADV
iajs-3457	28	22	practical	practical	ADJ
iajs-3457	28	23	therapy	therapy	NOUN
iajs-3457	28	24	option[9	option[9	NOUN
iajs-3457	28	25	]	]	PUNCT
iajs-3457	28	26	.	.	PUNCT
iajs-3457	29	1	the	the	DET
iajs-3457	29	2	liver	liver	NOUN
iajs-3457	29	3	,	,	PUNCT
iajs-3457	29	4	spleen	spleen	NOUN
iajs-3457	29	5	,	,	PUNCT
iajs-3457	29	6	myocardium	myocardium	ADJ
iajs-3457	29	7	,	,	PUNCT
iajs-3457	29	8	placenta	placenta	ADJ
iajs-3457	29	9	,	,	PUNCT
iajs-3457	29	10	and	and	CCONJ
iajs-3457	29	11	other	other	ADJ
iajs-3457	29	12	organs	organ	NOUN
iajs-3457	29	13	produce	produce	VERB
iajs-3457	29	14	ferritin	ferritin	ADJ
iajs-3457	29	15	,	,	PUNCT
iajs-3457	29	16	a	a	DET
iajs-3457	29	17	huge	huge	ADJ
iajs-3457	29	18	macromolecule	macromolecule	NOUN
iajs-3457	29	19	with	with	ADP
iajs-3457	29	20	a	a	DET
iajs-3457	29	21	molecular	molecular	ADJ
iajs-3457	29	22	weight	weight	NOUN
iajs-3457	29	23	of	of	ADP
iajs-3457	29	24	450	450	NUM
iajs-3457	29	25	kda	kda	NOUN
iajs-3457	29	26	,	,	PUNCT
iajs-3457	29	27	which	which	PRON
iajs-3457	29	28	is	be	AUX
iajs-3457	29	29	crucial	crucial	ADJ
iajs-3457	29	30	for	for	ADP
iajs-3457	29	31	iron	iron	NOUN
iajs-3457	29	32	storage	storage	NOUN
iajs-3457	29	33	.	.	PUNCT
iajs-3457	30	1	since	since	SCONJ
iajs-3457	30	2	serum	serum	NOUN
iajs-3457	30	3	ferritin	ferritin	PROPN
iajs-3457	30	4	measurement	measurement	NOUN
iajs-3457	30	5	is	be	AUX
iajs-3457	30	6	most	most	ADV
iajs-3457	30	7	commonly	commonly	ADV
iajs-3457	30	8	used	use	VERB
iajs-3457	30	9	in	in	ADP
iajs-3457	30	10	the	the	DET
iajs-3457	30	11	differential	differential	ADJ
iajs-3457	30	12	diagnosis	diagnosis	NOUN
iajs-3457	30	13	of	of	ADP
iajs-3457	30	14	anemia	anemia	NOUN
iajs-3457	30	15	because	because	SCONJ
iajs-3457	30	16	ferritin	ferritin	ADJ
iajs-3457	30	17	is	be	AUX
iajs-3457	30	18	a	a	DET
iajs-3457	30	19	sensitive	sensitive	ADJ
iajs-3457	30	20	sign	sign	NOUN
iajs-3457	30	21	of	of	ADP
iajs-3457	30	22	iron	iron	NOUN
iajs-3457	30	23	shortage	shortage	NOUN
iajs-3457	30	24	,	,	PUNCT
iajs-3457	30	25	iron	iron	NOUN
iajs-3457	30	26	excess	excess	NOUN
iajs-3457	30	27	(	(	PUNCT
iajs-3457	30	28	hemochromatosis	hemochromatosis	NOUN
iajs-3457	30	29	or	or	CCONJ
iajs-3457	30	30	haemosiderosis	haemosiderosis	NOUN
iajs-3457	30	31	)	)	PUNCT
iajs-3457	30	32	,	,	PUNCT
iajs-3457	30	33	infection	infection	NOUN
iajs-3457	30	34	or	or	CCONJ
iajs-3457	30	35	inflammation	inflammation	NOUN
iajs-3457	30	36	,	,	PUNCT
iajs-3457	30	37	neurological	neurological	ADJ
iajs-3457	30	38	illnesses	illness	NOUN
iajs-3457	30	39	,	,	PUNCT
iajs-3457	30	40	cancers	cancer	NOUN
iajs-3457	30	41	,	,	PUNCT
iajs-3457	30	42	and	and	CCONJ
iajs-3457	30	43	liver	liver	NOUN
iajs-3457	30	44	tissue	tissue	NOUN
iajs-3457	30	45	damage	damage	NOUN
iajs-3457	30	46	can	can	AUX
iajs-3457	30	47	all	all	PRON
iajs-3457	30	48	result	result	VERB
iajs-3457	30	49	in	in	ADP
iajs-3457	30	50	a	a	DET
iajs-3457	30	51	rise	rise	NOUN
iajs-3457	30	52	in	in	ADP
iajs-3457	30	53	ferritin	ferritin	ADJ
iajs-3457	30	54	levels	level	NOUN
iajs-3457	30	55	[	[	X
iajs-3457	30	56	10	10	NUM
iajs-3457	30	57	]	]	PUNCT
iajs-3457	30	58	.	.	PUNCT
iajs-3457	31	1	ferritins	ferritin	NOUN
iajs-3457	31	2	have	have	VERB
iajs-3457	31	3	special	special	ADJ
iajs-3457	31	4	chemical	chemical	NOUN
iajs-3457	31	5	and	and	CCONJ
iajs-3457	31	6	physical	physical	ADJ
iajs-3457	31	7	characteristics	characteristic	NOUN
iajs-3457	31	8	.	.	PUNCT
iajs-3457	32	1	in	in	ADP
iajs-3457	32	2	addition	addition	NOUN
iajs-3457	32	3	to	to	ADP
iajs-3457	32	4	being	be	AUX
iajs-3457	32	5	stable	stable	ADJ
iajs-3457	32	6	in	in	ADP
iajs-3457	32	7	a	a	DET
iajs-3457	32	8	variety	variety	NOUN
iajs-3457	32	9	of	of	ADP
iajs-3457	32	10	denaturants	denaturant	NOUN
iajs-3457	32	11	like	like	ADP
iajs-3457	32	12	urea	urea	NOUN
iajs-3457	32	13	or	or	CCONJ
iajs-3457	32	14	guanidinium	guanidinium	NOUN
iajs-3457	32	15	chloride	chloride	NOUN
iajs-3457	32	16	,	,	PUNCT
iajs-3457	32	17	ferritin	ferritin	NOUN
iajs-3457	32	18	can	can	AUX
iajs-3457	32	19	withstand	withstand	VERB
iajs-3457	32	20	extreme	extreme	ADJ
iajs-3457	32	21	temperatures	temperature	NOUN
iajs-3457	32	22	of	of	ADP
iajs-3457	32	23	up	up	ADP
iajs-3457	32	24	to	to	PART
iajs-3457	32	25	75	75	NUM
iajs-3457	32	26	°	°	NOUN
iajs-3457	32	27	c	c	NOUN
iajs-3457	32	28	for	for	ADP
iajs-3457	32	29	a	a	DET
iajs-3457	32	30	period	period	NOUN
iajs-3457	32	31	of	of	ADP
iajs-3457	32	32	time	time	NOUN
iajs-3457	32	33	.	.	PUNCT
iajs-3457	33	1	the	the	DET
iajs-3457	33	2	abundance	abundance	NOUN
iajs-3457	33	3	of	of	ADP
iajs-3457	33	4	salt	salt	NOUN
iajs-3457	33	5	bridges	bridge	NOUN
iajs-3457	33	6	and	and	CCONJ
iajs-3457	33	7	hydrogen	hydrogen	NOUN
iajs-3457	33	8	bonds	bond	NOUN
iajs-3457	33	9	between	between	ADP
iajs-3457	33	10	its	its	PRON
iajs-3457	33	11	subunits	subunit	NOUN
iajs-3457	33	12	contribute	contribute	VERB
iajs-3457	33	13	to	to	ADP
iajs-3457	33	14	ferritin	ferritin	NOUN
iajs-3457	33	15	's	's	PART
iajs-3457	33	16	unique	unique	ADJ
iajs-3457	33	17	properties	property	NOUN
iajs-3457	33	18	[	[	X
iajs-3457	33	19	11	11	NUM
iajs-3457	33	20	]	]	PUNCT
iajs-3457	33	21	.	.	PUNCT
iajs-3457	34	1	furthermore	furthermore	ADV
iajs-3457	34	2	,	,	PUNCT
iajs-3457	34	3	ferritin	ferritin	ADJ
iajs-3457	34	4	is	be	AUX
iajs-3457	34	5	the	the	DET
iajs-3457	34	6	primary	primary	ADJ
iajs-3457	34	7	protein	protein	NOUN
iajs-3457	34	8	that	that	PRON
iajs-3457	34	9	stores	store	VERB
iajs-3457	34	10	iron	iron	NOUN
iajs-3457	34	11	in	in	ADP
iajs-3457	34	12	the	the	DET
iajs-3457	34	13	body	body	NOUN
iajs-3457	34	14	.	.	PUNCT
iajs-3457	35	1	these	these	DET
iajs-3457	35	2	proteins	protein	NOUN
iajs-3457	35	3	control	control	VERB
iajs-3457	35	4	the	the	DET
iajs-3457	35	5	production	production	NOUN
iajs-3457	35	6	of	of	ADP
iajs-3457	35	7	mrna	mrna	PROPN
iajs-3457	35	8	by	by	ADP
iajs-3457	35	9	acting	act	VERB
iajs-3457	35	10	as	as	ADP
iajs-3457	35	11	iron	iron	NOUN
iajs-3457	35	12	regulatory	regulatory	ADJ
iajs-3457	35	13	proteins	protein	NOUN
iajs-3457	35	14	.	.	PUNCT
iajs-3457	36	1	it	it	PRON
iajs-3457	36	2	plays	play	VERB
iajs-3457	36	3	a	a	DET
iajs-3457	36	4	crucial	crucial	ADJ
iajs-3457	36	5	role	role	NOUN
iajs-3457	36	6	in	in	ADP
iajs-3457	36	7	maintaining	maintain	VERB
iajs-3457	36	8	iron	iron	NOUN
iajs-3457	36	9	homeostasis	homeostasis	NOUN
iajs-3457	36	10	because	because	SCONJ
iajs-3457	36	11	of	of	ADP
iajs-3457	36	12	its	its	PRON
iajs-3457	36	13	ability	ability	NOUN
iajs-3457	36	14	to	to	PART
iajs-3457	36	15	bind	bind	VERB
iajs-3457	36	16	to	to	ADP
iajs-3457	36	17	and	and	CCONJ
iajs-3457	36	18	sequester	sequester	VERB
iajs-3457	36	19	intracellular	intracellular	ADJ
iajs-3457	36	20	iron	iron	NOUN
iajs-3457	36	21	[	[	X
iajs-3457	36	22	12	12	NUM
iajs-3457	36	23	]	]	PUNCT
iajs-3457	36	24	.	.	PUNCT
iajs-3457	37	1	the	the	DET
iajs-3457	37	2	liver	liver	NOUN
iajs-3457	37	3	creates	create	VERB
iajs-3457	37	4	crp	crp	PROPN
iajs-3457	37	5	,	,	PUNCT
iajs-3457	37	6	a	a	DET
iajs-3457	37	7	pentameric	pentameric	ADJ
iajs-3457	37	8	protein	protein	NOUN
iajs-3457	37	9	whose	whose	DET
iajs-3457	37	10	concentration	concentration	NOUN
iajs-3457	37	11	rises	rise	VERB
iajs-3457	37	12	in	in	ADP
iajs-3457	37	13	response	response	NOUN
iajs-3457	37	14	to	to	ADP
iajs-3457	37	15	inflammation	inflammation	NOUN
iajs-3457	37	16	.	.	PUNCT
iajs-3457	38	1	il-6	il-6	NOUN
iajs-3457	39	1	primarily	primarily	ADV
iajs-3457	39	2	triggers	trigger	VERB
iajs-3457	39	3	the	the	DET
iajs-3457	39	4	gene	gene	NOUN
iajs-3457	39	5	responsible	responsible	ADJ
iajs-3457	39	6	for	for	ADP
iajs-3457	39	7	crp	crp	NOUN
iajs-3457	39	8	transcription	transcription	NOUN
iajs-3457	39	9	during	during	ADP
iajs-3457	39	10	the	the	DET
iajs-3457	39	11	acute	acute	ADJ
iajs-3457	39	12	phase	phase	NOUN
iajs-3457	39	13	of	of	ADP
iajs-3457	39	14	an	an	DET
iajs-3457	39	15	inflammatory	inflammatory	ADJ
iajs-3457	39	16	or	or	CCONJ
iajs-3457	39	17	viral	viral	ADJ
iajs-3457	39	18	event	event	NOUN
iajs-3457	39	19	[	[	X
iajs-3457	39	20	13	13	NUM
iajs-3457	39	21	]	]	PUNCT
iajs-3457	39	22	.	.	PUNCT
iajs-3457	40	1	c	c	X
iajs-3457	40	2	-	-	PUNCT
iajs-3457	40	3	reactive	reactive	ADJ
iajs-3457	40	4	proteins	protein	NOUN
iajs-3457	40	5	provide	provide	VERB
iajs-3457	40	6	the	the	DET
iajs-3457	40	7	first	first	ADJ
iajs-3457	40	8	line	line	NOUN
iajs-3457	40	9	of	of	ADP
iajs-3457	40	10	defense	defense	NOUN
iajs-3457	40	11	against	against	ADP
iajs-3457	40	12	infections	infection	NOUN
iajs-3457	40	13	.	.	PUNCT
iajs-3457	41	1	even	even	ADV
iajs-3457	41	2	though	though	SCONJ
iajs-3457	41	3	they	they	PRON
iajs-3457	41	4	are	be	AUX
iajs-3457	41	5	structurally	structurally	ADV
iajs-3457	41	6	different	different	ADJ
iajs-3457	41	7	,	,	PUNCT
iajs-3457	41	8	crp	crp	PROPN
iajs-3457	41	9	and	and	CCONJ
iajs-3457	41	10	immunoglobulin	immunoglobulin	PROPN
iajs-3457	41	11	(	(	PUNCT
iajs-3457	41	12	ig	ig	NOUN
iajs-3457	41	13	)	)	PUNCT
iajs-3457	41	14	molecules	molecule	NOUN
iajs-3457	41	15	share	share	VERB
iajs-3457	41	16	many	many	ADJ
iajs-3457	41	17	functional	functional	ADJ
iajs-3457	41	18	traits	trait	NOUN
iajs-3457	41	19	.	.	PUNCT
iajs-3457	42	1	the	the	DET
iajs-3457	42	2	binding	bind	VERB
iajs-3457	42	3	specificities	specificity	NOUN
iajs-3457	42	4	and	and	CCONJ
iajs-3457	42	5	the	the	DET
iajs-3457	42	6	site	site	NOUN
iajs-3457	42	7	of	of	ADP
iajs-3457	42	8	synthesis	synthesis	NOUN
iajs-3457	42	9	of	of	ADP
iajs-3457	42	10	crp	crp	PROPN
iajs-3457	42	11	,	,	PUNCT
iajs-3457	42	12	which	which	PRON
iajs-3457	42	13	give	give	VERB
iajs-3457	42	14	rise	rise	NOUN
iajs-3457	42	15	to	to	ADP
iajs-3457	42	16	a	a	DET
iajs-3457	42	17	new	new	ADJ
iajs-3457	42	18	superfamily	superfamily	NOUN
iajs-3457	42	19	of	of	ADP
iajs-3457	42	20	proteins	protein	NOUN
iajs-3457	42	21	,	,	PUNCT
iajs-3457	42	22	are	be	AUX
iajs-3457	42	23	additional	additional	ADJ
iajs-3457	42	24	distinguishing	distinguish	VERB
iajs-3457	42	25	features	feature	NOUN
iajs-3457	42	26	.	.	PUNCT
iajs-3457	43	1	the	the	DET
iajs-3457	43	2	quantitative	quantitative	ADJ
iajs-3457	43	3	measurement	measurement	NOUN
iajs-3457	43	4	of	of	ADP
iajs-3457	43	5	crp	crp	PROPN
iajs-3457	43	6	levels	level	NOUN
iajs-3457	43	7	in	in	ADP
iajs-3457	43	8	serum	serum	NOUN
iajs-3457	43	9	is	be	AUX
iajs-3457	43	10	widely	widely	ADV
iajs-3457	43	11	used	use	VERB
iajs-3457	43	12	by	by	ADP
iajs-3457	43	13	clinical	clinical	ADJ
iajs-3457	43	14	practitioners	practitioner	NOUN
iajs-3457	43	15	as	as	ADP
iajs-3457	43	16	a	a	DET
iajs-3457	43	17	sensitive	sensitive	ADJ
iajs-3457	43	18	indicator	indicator	NOUN
iajs-3457	43	19	of	of	ADP
iajs-3457	43	20	inflammation	inflammation	NOUN
iajs-3457	43	21	.	.	PUNCT
iajs-3457	44	1	in	in	ADP
iajs-3457	44	2	addition	addition	NOUN
iajs-3457	44	3	to	to	ADP
iajs-3457	44	4	its	its	PRON
iajs-3457	44	5	involvement	involvement	NOUN
iajs-3457	44	6	in	in	ADP
iajs-3457	44	7	removing	remove	VERB
iajs-3457	44	8	germs	germ	NOUN
iajs-3457	44	9	and	and	CCONJ
iajs-3457	44	10	damaged	damage	VERB
iajs-3457	44	11	or	or	CCONJ
iajs-3457	44	12	dying	die	VERB
iajs-3457	44	13	cells	cell	NOUN
iajs-3457	44	14	,	,	PUNCT
iajs-3457	44	15	crp	crp	PROPN
iajs-3457	44	16	may	may	AUX
iajs-3457	44	17	also	also	ADV
iajs-3457	44	18	perform	perform	VERB
iajs-3457	44	19	more	more	ADV
iajs-3457	44	20	intricate	intricate	ADJ
iajs-3457	44	21	immunomodulatory	immunomodulatory	ADJ
iajs-3457	44	22	tasks	task	NOUN
iajs-3457	44	23	[	[	X
iajs-3457	44	24	14	14	NUM
iajs-3457	44	25	]	]	PUNCT
iajs-3457	44	26	.	.	PUNCT
iajs-3457	45	1	in	in	ADP
iajs-3457	45	2	β	β	NOUN
iajs-3457	45	3	-	-	NOUN
iajs-3457	45	4	thalassemia	thalassemia	NOUN
iajs-3457	45	5	,	,	PUNCT
iajs-3457	45	6	crp	crp	PROPN
iajs-3457	45	7	is	be	AUX
iajs-3457	45	8	primarily	primarily	ADV
iajs-3457	45	9	employed	employ	VERB
iajs-3457	45	10	as	as	ADP
iajs-3457	45	11	a	a	DET
iajs-3457	45	12	marker	marker	NOUN
iajs-3457	45	13	of	of	ADP
iajs-3457	45	14	infection	infection	NOUN
iajs-3457	45	15	and	and	CCONJ
iajs-3457	45	16	inflammation	inflammation	NOUN
iajs-3457	45	17	.	.	PUNCT
iajs-3457	46	1	crp	crp	PROPN
iajs-3457	46	2	ihjpas	ihjpas	PROPN
iajs-3457	46	3	.	.	PUNCT
iajs-3457	47	1	2024	2024	NUM
iajs-3457	47	2	,	,	PUNCT
iajs-3457	47	3	37(4	37(4	NOUN
iajs-3457	47	4	)	)	PUNCT
iajs-3457	47	5	37	37	NUM
iajs-3457	47	6	readings	reading	NOUN
iajs-3457	47	7	can	can	AUX
iajs-3457	47	8	be	be	AUX
iajs-3457	47	9	measured	measure	VERB
iajs-3457	47	10	and	and	CCONJ
iajs-3457	47	11	plotted	plot	VERB
iajs-3457	47	12	to	to	PART
iajs-3457	47	13	help	help	VERB
iajs-3457	47	14	track	track	VERB
iajs-3457	47	15	the	the	DET
iajs-3457	47	16	progression	progression	NOUN
iajs-3457	47	17	of	of	ADP
iajs-3457	47	18	a	a	DET
iajs-3457	47	19	disease	disease	NOUN
iajs-3457	47	20	or	or	CCONJ
iajs-3457	47	21	evaluate	evaluate	VERB
iajs-3457	47	22	the	the	DET
iajs-3457	47	23	efficacy	efficacy	NOUN
iajs-3457	47	24	of	of	ADP
iajs-3457	47	25	treatment	treatment	NOUN
iajs-3457	47	26	[	[	X
iajs-3457	47	27	15	15	NUM
iajs-3457	47	28	]	]	PUNCT
iajs-3457	47	29	.	.	PUNCT
iajs-3457	48	1	pro	pro	ADJ
iajs-3457	48	2	-	-	ADJ
iajs-3457	48	3	inflammatory	inflammatory	ADJ
iajs-3457	48	4	cytokines	cytokine	NOUN
iajs-3457	48	5	are	be	AUX
iajs-3457	48	6	small	small	ADJ
iajs-3457	48	7	signaling	signal	VERB
iajs-3457	48	8	proteins	protein	NOUN
iajs-3457	48	9	that	that	PRON
iajs-3457	48	10	are	be	AUX
iajs-3457	48	11	necessary	necessary	ADJ
iajs-3457	48	12	for	for	ADP
iajs-3457	48	13	beginning	begin	VERB
iajs-3457	48	14	and	and	CCONJ
iajs-3457	48	15	promoting	promote	VERB
iajs-3457	48	16	inflammatory	inflammatory	ADJ
iajs-3457	48	17	reactions	reaction	NOUN
iajs-3457	48	18	in	in	ADP
iajs-3457	48	19	diseases	disease	NOUN
iajs-3457	48	20	,	,	PUNCT
iajs-3457	48	21	and	and	CCONJ
iajs-3457	48	22	they	they	PRON
iajs-3457	48	23	are	be	AUX
iajs-3457	48	24	up	up	ADV
iajs-3457	48	25	-	-	PUNCT
iajs-3457	48	26	regulated	regulate	VERB
iajs-3457	48	27	during	during	ADP
iajs-3457	48	28	inflammation	inflammation	NOUN
iajs-3457	48	29	.	.	PUNCT
iajs-3457	49	1	[	[	X
iajs-3457	49	2	16	16	NUM
iajs-3457	49	3	]	]	PUNCT
iajs-3457	49	4	.	.	PUNCT
iajs-3457	50	1	cytokines	cytokine	NOUN
iajs-3457	50	2	regulate	regulate	VERB
iajs-3457	50	3	the	the	DET
iajs-3457	50	4	balance	balance	NOUN
iajs-3457	50	5	between	between	ADP
iajs-3457	50	6	innate	innate	ADJ
iajs-3457	50	7	and	and	CCONJ
iajs-3457	50	8	adaptive	adaptive	ADJ
iajs-3457	50	9	immune	immune	ADJ
iajs-3457	50	10	responses	response	NOUN
iajs-3457	50	11	.	.	PUNCT
iajs-3457	51	1	proinflammatory	proinflammatory	ADJ
iajs-3457	51	2	and	and	CCONJ
iajs-3457	51	3	anti	anti	ADJ
iajs-3457	51	4	-	-	ADJ
iajs-3457	51	5	inflammatory	inflammatory	ADJ
iajs-3457	51	6	cytokines	cytokine	NOUN
iajs-3457	51	7	,	,	PUNCT
iajs-3457	51	8	including	include	VERB
iajs-3457	51	9	il-6	il-6	NUM
iajs-3457	51	10	,	,	PUNCT
iajs-3457	51	11	il-1	il-1	NUM
iajs-3457	51	12	,	,	PUNCT
iajs-3457	51	13	tnf	tnf	PROPN
iajs-3457	51	14	-	-	PUNCT
iajs-3457	51	15	β	β	PROPN
iajs-3457	51	16	,	,	PUNCT
iajs-3457	51	17	and	and	CCONJ
iajs-3457	51	18	il-10	il-10	PRON
iajs-3457	51	19	,	,	PUNCT
iajs-3457	51	20	have	have	VERB
iajs-3457	51	21	a	a	DET
iajs-3457	51	22	significant	significant	ADJ
iajs-3457	51	23	impact	impact	NOUN
iajs-3457	51	24	on	on	ADP
iajs-3457	51	25	the	the	DET
iajs-3457	51	26	immune	immune	ADJ
iajs-3457	51	27	response	response	NOUN
iajs-3457	51	28	.	.	PUNCT
iajs-3457	52	1	an	an	DET
iajs-3457	52	2	imbalance	imbalance	NOUN
iajs-3457	52	3	in	in	ADP
iajs-3457	52	4	their	their	PRON
iajs-3457	52	5	production	production	NOUN
iajs-3457	52	6	may	may	AUX
iajs-3457	52	7	result	result	VERB
iajs-3457	52	8	in	in	ADP
iajs-3457	52	9	immunological	immunological	ADJ
iajs-3457	52	10	dysfunction	dysfunction	NOUN
iajs-3457	52	11	,	,	PUNCT
iajs-3457	52	12	encouraging	encourage	VERB
iajs-3457	52	13	the	the	DET
iajs-3457	52	14	genesis	genesis	NOUN
iajs-3457	52	15	of	of	ADP
iajs-3457	52	16	inflammatory	inflammatory	ADJ
iajs-3457	52	17	disorders	disorder	NOUN
iajs-3457	52	18	[	[	X
iajs-3457	52	19	17	17	NUM
iajs-3457	52	20	]	]	PUNCT
iajs-3457	52	21	.	.	PUNCT
iajs-3457	53	1	interleukin-1β	interleukin-1β	PROPN
iajs-3457	53	2	is	be	AUX
iajs-3457	53	3	one	one	NUM
iajs-3457	53	4	of	of	ADP
iajs-3457	53	5	the	the	DET
iajs-3457	53	6	pro	pro	ADJ
iajs-3457	53	7	-	-	ADJ
iajs-3457	53	8	inflammatory	inflammatory	ADJ
iajs-3457	53	9	cytokines	cytokine	NOUN
iajs-3457	53	10	thought	think	VERB
iajs-3457	53	11	to	to	PART
iajs-3457	53	12	be	be	AUX
iajs-3457	53	13	involved	involve	VERB
iajs-3457	53	14	in	in	ADP
iajs-3457	53	15	the	the	DET
iajs-3457	53	16	evolution	evolution	NOUN
iajs-3457	53	17	of	of	ADP
iajs-3457	53	18	inflammatory	inflammatory	ADJ
iajs-3457	53	19	disorders	disorder	NOUN
iajs-3457	53	20	such	such	ADJ
iajs-3457	53	21	as	as	ADP
iajs-3457	53	22	sepsis	sepsis	NOUN
iajs-3457	53	23	,	,	PUNCT
iajs-3457	53	24	diabetic	diabetic	ADJ
iajs-3457	53	25	nephropathy	nephropathy	NOUN
iajs-3457	53	26	,	,	PUNCT
iajs-3457	53	27	cardiovascular	cardiovascular	ADJ
iajs-3457	53	28	disease	disease	NOUN
iajs-3457	53	29	,	,	PUNCT
iajs-3457	53	30	and	and	CCONJ
iajs-3457	53	31	autoimmune	autoimmune	ADJ
iajs-3457	53	32	disease	disease	NOUN
iajs-3457	53	33	[	[	X
iajs-3457	53	34	18	18	NUM
iajs-3457	53	35	]	]	PUNCT
iajs-3457	53	36	.	.	PUNCT
iajs-3457	54	1	interleukin-1β	interleukin-1β	PROPN
iajs-3457	54	2	is	be	AUX
iajs-3457	54	3	made	make	VERB
iajs-3457	54	4	by	by	ADP
iajs-3457	54	5	different	different	ADJ
iajs-3457	54	6	types	type	NOUN
iajs-3457	54	7	of	of	ADP
iajs-3457	54	8	cells	cell	NOUN
iajs-3457	54	9	,	,	PUNCT
iajs-3457	54	10	like	like	ADP
iajs-3457	54	11	b	b	NOUN
iajs-3457	54	12	-	-	PUNCT
iajs-3457	54	13	cells	cell	NOUN
iajs-3457	54	14	,	,	PUNCT
iajs-3457	54	15	macrophages	macrophage	NOUN
iajs-3457	54	16	,	,	PUNCT
iajs-3457	54	17	and	and	CCONJ
iajs-3457	54	18	fibroblasts	fibroblast	NOUN
iajs-3457	54	19	.	.	PUNCT
iajs-3457	55	1	it	it	PRON
iajs-3457	55	2	has	have	VERB
iajs-3457	55	3	two	two	NUM
iajs-3457	55	4	structurally	structurally	ADV
iajs-3457	55	5	different	different	ADJ
iajs-3457	55	6	forms	form	NOUN
iajs-3457	55	7	,	,	PUNCT
iajs-3457	55	8	il-1α	il-1α	PROPN
iajs-3457	55	9	and	and	CCONJ
iajs-3457	55	10	il-1β	il-1β	PROPN
iajs-3457	55	11	,	,	PUNCT
iajs-3457	55	12	which	which	PRON
iajs-3457	55	13	each	each	PRON
iajs-3457	55	14	have	have	VERB
iajs-3457	55	15	their	their	PRON
iajs-3457	55	16	functions	function	NOUN
iajs-3457	55	17	[	[	X
iajs-3457	55	18	19	19	NUM
iajs-3457	55	19	]	]	PUNCT
iajs-3457	55	20	.	.	PUNCT
iajs-3457	56	1	a	a	DET
iajs-3457	56	2	higher	high	ADJ
iajs-3457	56	3	level	level	NOUN
iajs-3457	56	4	of	of	ADP
iajs-3457	56	5	il-1	il-1	PUNCT
iajs-3457	56	6	in	in	ADP
iajs-3457	56	7	the	the	DET
iajs-3457	56	8	blood	blood	NOUN
iajs-3457	56	9	of	of	ADP
iajs-3457	56	10	people	people	NOUN
iajs-3457	56	11	with	with	ADP
iajs-3457	56	12	β	β	NOUN
iajs-3457	56	13	-	-	NOUN
iajs-3457	56	14	thalassemia	thalassemia	NOUN
iajs-3457	56	15	means	mean	VERB
iajs-3457	56	16	that	that	SCONJ
iajs-3457	56	17	more	more	ADJ
iajs-3457	56	18	cells	cell	NOUN
iajs-3457	56	19	are	be	AUX
iajs-3457	56	20	dying	die	VERB
iajs-3457	56	21	,	,	PUNCT
iajs-3457	56	22	which	which	PRON
iajs-3457	56	23	makes	make	VERB
iajs-3457	56	24	erythropoiesis	erythropoiesis	NOUN
iajs-3457	56	25	less	less	ADV
iajs-3457	56	26	effective	effective	ADJ
iajs-3457	56	27	in	in	ADP
iajs-3457	56	28	these	these	DET
iajs-3457	56	29	people	people	NOUN
iajs-3457	56	30	[	[	X
iajs-3457	56	31	20	20	NUM
iajs-3457	56	32	]	]	PUNCT
iajs-3457	56	33	.	.	PUNCT
iajs-3457	57	1	a	a	DET
iajs-3457	57	2	diverse	diverse	ADJ
iajs-3457	57	3	range	range	NOUN
iajs-3457	57	4	of	of	ADP
iajs-3457	57	5	cells	cell	NOUN
iajs-3457	57	6	,	,	PUNCT
iajs-3457	57	7	including	include	VERB
iajs-3457	57	8	smooth	smooth	ADJ
iajs-3457	57	9	muscle	muscle	NOUN
iajs-3457	57	10	cells	cell	NOUN
iajs-3457	57	11	,	,	PUNCT
iajs-3457	57	12	mononuclear	mononuclear	ADJ
iajs-3457	57	13	macrophages	macrophage	NOUN
iajs-3457	57	14	,	,	PUNCT
iajs-3457	57	15	t	t	PROPN
iajs-3457	57	16	helper	helper	NOUN
iajs-3457	57	17	2	2	NUM
iajs-3457	57	18	cells	cell	NOUN
iajs-3457	57	19	,	,	PUNCT
iajs-3457	57	20	vascular	vascular	ADJ
iajs-3457	57	21	endothelial	endothelial	ADJ
iajs-3457	57	22	cells	cell	NOUN
iajs-3457	57	23	,	,	PUNCT
iajs-3457	57	24	fibroblasts	fibroblast	NOUN
iajs-3457	57	25	,	,	PUNCT
iajs-3457	57	26	and	and	CCONJ
iajs-3457	57	27	b	b	X
iajs-3457	57	28	cells	cell	NOUN
iajs-3457	57	29	,	,	PUNCT
iajs-3457	57	30	produce	produce	VERB
iajs-3457	57	31	interleukin-6	interleukin-6	NUM
iajs-3457	57	32	,	,	PUNCT
iajs-3457	57	33	a	a	DET
iajs-3457	57	34	186	186	NUM
iajs-3457	57	35	amino	amino	NOUN
iajs-3457	57	36	acid	acid	NOUN
iajs-3457	57	37	glycosylated	glycosylate	VERB
iajs-3457	57	38	protein	protein	NOUN
iajs-3457	57	39	[	[	X
iajs-3457	57	40	21	21	NUM
iajs-3457	57	41	]	]	PUNCT
iajs-3457	57	42	.	.	PUNCT
iajs-3457	58	1	this	this	DET
iajs-3457	58	2	soluble	soluble	ADJ
iajs-3457	58	3	cytokine	cytokine	NOUN
iajs-3457	58	4	influences	influence	VERB
iajs-3457	58	5	the	the	DET
iajs-3457	58	6	immune	immune	ADJ
iajs-3457	58	7	response	response	NOUN
iajs-3457	58	8	,	,	PUNCT
iajs-3457	58	9	inflammation	inflammation	NOUN
iajs-3457	58	10	,	,	PUNCT
iajs-3457	58	11	and	and	CCONJ
iajs-3457	58	12	hematopoiesis	hematopoiesis	NOUN
iajs-3457	58	13	in	in	ADP
iajs-3457	58	14	numerous	numerous	ADJ
iajs-3457	58	15	ways	way	NOUN
iajs-3457	58	16	.	.	PUNCT
iajs-3457	59	1	released	release	VERB
iajs-3457	59	2	in	in	ADP
iajs-3457	59	3	response	response	NOUN
iajs-3457	59	4	to	to	ADP
iajs-3457	59	5	infections	infection	NOUN
iajs-3457	59	6	and	and	CCONJ
iajs-3457	59	7	tissue	tissue	NOUN
iajs-3457	59	8	damage	damage	NOUN
iajs-3457	59	9	,	,	PUNCT
iajs-3457	59	10	it	it	PRON
iajs-3457	59	11	serves	serve	VERB
iajs-3457	59	12	as	as	ADP
iajs-3457	59	13	a	a	DET
iajs-3457	59	14	key	key	ADJ
iajs-3457	59	15	mediator	mediator	NOUN
iajs-3457	59	16	of	of	ADP
iajs-3457	59	17	fever	fever	NOUN
iajs-3457	59	18	and	and	CCONJ
iajs-3457	59	19	the	the	DET
iajs-3457	59	20	acute	acute	ADJ
iajs-3457	59	21	phase	phase	NOUN
iajs-3457	59	22	of	of	ADP
iajs-3457	59	23	the	the	DET
iajs-3457	59	24	immunological	immunological	ADJ
iajs-3457	59	25	reaction	reaction	NOUN
iajs-3457	59	26	,	,	PUNCT
iajs-3457	59	27	boosting	boost	VERB
iajs-3457	59	28	the	the	DET
iajs-3457	59	29	immune	immune	ADJ
iajs-3457	59	30	response	response	NOUN
iajs-3457	59	31	[	[	X
iajs-3457	59	32	22	22	NUM
iajs-3457	59	33	]	]	PUNCT
iajs-3457	59	34	.	.	PUNCT
iajs-3457	60	1	it	it	PRON
iajs-3457	60	2	is	be	AUX
iajs-3457	60	3	well	well	ADV
iajs-3457	60	4	known	know	VERB
iajs-3457	60	5	that	that	SCONJ
iajs-3457	60	6	il-6	il-6	NOUN
iajs-3457	60	7	plays	play	VERB
iajs-3457	60	8	a	a	DET
iajs-3457	60	9	significant	significant	ADJ
iajs-3457	60	10	role	role	NOUN
iajs-3457	60	11	in	in	ADP
iajs-3457	60	12	the	the	DET
iajs-3457	60	13	proinflammatory	proinflammatory	ADJ
iajs-3457	60	14	response	response	NOUN
iajs-3457	60	15	,	,	PUNCT
iajs-3457	60	16	and	and	CCONJ
iajs-3457	60	17	that	that	SCONJ
iajs-3457	60	18	its	its	PRON
iajs-3457	60	19	high	high	ADJ
iajs-3457	60	20	serum	serum	NOUN
iajs-3457	60	21	level	level	NOUN
iajs-3457	60	22	may	may	AUX
iajs-3457	60	23	affect	affect	VERB
iajs-3457	60	24	the	the	DET
iajs-3457	60	25	pathophysiology	pathophysiology	NOUN
iajs-3457	60	26	of	of	ADP
iajs-3457	60	27	β	β	NOUN
iajs-3457	60	28	-	-	NOUN
iajs-3457	60	29	thalassemia	thalassemia	NOUN
iajs-3457	60	30	[	[	X
iajs-3457	60	31	23	23	NUM
iajs-3457	60	32	]	]	PUNCT
iajs-3457	60	33	.	.	PUNCT
iajs-3457	61	1	2	2	X
iajs-3457	61	2	.	.	X
iajs-3457	61	3	materials	material	NOUN
iajs-3457	61	4	and	and	CCONJ
iajs-3457	61	5	methods	method	NOUN
iajs-3457	61	6	sixty	sixty	NUM
iajs-3457	61	7	patients	patient	NOUN
iajs-3457	61	8	(	(	PUNCT
iajs-3457	61	9	male	male	ADJ
iajs-3457	61	10	and	and	CCONJ
iajs-3457	61	11	female	female	NOUN
iajs-3457	61	12	)	)	PUNCT
iajs-3457	61	13	with	with	ADP
iajs-3457	61	14	β	β	NOUN
iajs-3457	61	15	-	-	NOUN
iajs-3457	61	16	thalassemia	thalassemia	NOUN
iajs-3457	61	17	and	and	CCONJ
iajs-3457	61	18	thirty	thirty	NUM
iajs-3457	61	19	healthy	healthy	ADJ
iajs-3457	61	20	subjects	subject	NOUN
iajs-3457	61	21	were	be	AUX
iajs-3457	61	22	interested	interested	ADJ
iajs-3457	61	23	in	in	ADP
iajs-3457	61	24	this	this	DET
iajs-3457	61	25	study	study	NOUN
iajs-3457	61	26	because	because	SCONJ
iajs-3457	61	27	of	of	ADP
iajs-3457	61	28	their	their	PRON
iajs-3457	61	29	presence	presence	NOUN
iajs-3457	61	30	at	at	ADP
iajs-3457	61	31	"	"	PUNCT
iajs-3457	61	32	abin	abin	PROPN
iajs-3457	61	33	al	al	PROPN
iajs-3457	61	34	-	-	PUNCT
iajs-3457	61	35	baladi	baladi	PROPN
iajs-3457	61	36	hospital	hospital	NOUN
iajs-3457	61	37	in	in	ADP
iajs-3457	61	38	baghdad	baghdad	PROPN
iajs-3457	61	39	.	.	PUNCT
iajs-3457	61	40	"	"	PUNCT
iajs-3457	62	1	we	we	PRON
iajs-3457	62	2	conducted	conduct	VERB
iajs-3457	62	3	the	the	DET
iajs-3457	62	4	research	research	NOUN
iajs-3457	62	5	from	from	ADP
iajs-3457	62	6	september	september	PROPN
iajs-3457	62	7	2022	2022	NUM
iajs-3457	62	8	to	to	ADP
iajs-3457	62	9	january	january	PROPN
iajs-3457	62	10	2023	2023	NUM
iajs-3457	62	11	.	.	PUNCT
iajs-3457	63	1	despite	despite	SCONJ
iajs-3457	63	2	having	have	VERB
iajs-3457	63	3	thalassemia	thalassemia	NOUN
iajs-3457	63	4	major	major	NOUN
iajs-3457	63	5	for	for	ADP
iajs-3457	63	6	varying	vary	VERB
iajs-3457	63	7	lengths	length	NOUN
iajs-3457	63	8	of	of	ADP
iajs-3457	63	9	time	time	NOUN
iajs-3457	63	10	,	,	PUNCT
iajs-3457	63	11	all	all	DET
iajs-3457	63	12	patients	patient	NOUN
iajs-3457	63	13	received	receive	VERB
iajs-3457	63	14	normal	normal	ADJ
iajs-3457	63	15	treatment	treatment	NOUN
iajs-3457	63	16	.	.	PUNCT
iajs-3457	64	1	all	all	DET
iajs-3457	64	2	patients	patient	NOUN
iajs-3457	64	3	ranged	range	VERB
iajs-3457	64	4	in	in	ADP
iajs-3457	64	5	age	age	NOUN
iajs-3457	64	6	from	from	ADP
iajs-3457	64	7	15	15	NUM
iajs-3457	64	8	to	to	PART
iajs-3457	64	9	30	30	NUM
iajs-3457	64	10	years	year	NOUN
iajs-3457	64	11	,	,	PUNCT
iajs-3457	64	12	and	and	CCONJ
iajs-3457	64	13	we	we	PRON
iajs-3457	64	14	collected	collect	VERB
iajs-3457	64	15	the	the	DET
iajs-3457	64	16	necessary	necessary	ADJ
iajs-3457	64	17	data	datum	NOUN
iajs-3457	64	18	from	from	ADP
iajs-3457	64	19	them	they	PRON
iajs-3457	64	20	with	with	ADP
iajs-3457	64	21	their	their	PRON
iajs-3457	64	22	consent	consent	NOUN
iajs-3457	64	23	,	,	PUNCT
iajs-3457	64	24	adhering	adhere	VERB
iajs-3457	64	25	to	to	ADP
iajs-3457	64	26	the	the	DET
iajs-3457	64	27	ethics	ethic	NOUN
iajs-3457	64	28	code	code	NOUN
iajs-3457	64	29	csec/0922/0104	csec/0922/0104	NOUN
iajs-3457	64	30	of	of	ADP
iajs-3457	64	31	a	a	DET
iajs-3457	64	32	science	science	NOUN
iajs-3457	64	33	college	college	NOUN
iajs-3457	64	34	in	in	ADP
iajs-3457	64	35	2022/9/28	2022/9/28	NUM
iajs-3457	64	36	.	.	PUNCT
iajs-3457	65	1	clinicians	clinician	NOUN
iajs-3457	65	2	consistently	consistently	ADV
iajs-3457	65	3	checked	check	VERB
iajs-3457	65	4	each	each	DET
iajs-3457	65	5	patient	patient	NOUN
iajs-3457	65	6	once	once	ADV
iajs-3457	65	7	or	or	CCONJ
iajs-3457	65	8	twice	twice	DET
iajs-3457	65	9	every	every	DET
iajs-3457	65	10	month	month	NOUN
iajs-3457	65	11	;	;	PUNCT
iajs-3457	65	12	they	they	PRON
iajs-3457	65	13	received	receive	VERB
iajs-3457	65	14	erythrocyte	erythrocyte	NOUN
iajs-3457	65	15	transfusions	transfusion	NOUN
iajs-3457	65	16	on	on	ADP
iajs-3457	65	17	a	a	DET
iajs-3457	65	18	regular	regular	ADJ
iajs-3457	65	19	basis	basis	NOUN
iajs-3457	65	20	.	.	PUNCT
iajs-3457	66	1	all	all	DET
iajs-3457	66	2	patients	patient	NOUN
iajs-3457	66	3	had	have	VERB
iajs-3457	66	4	similar	similar	ADJ
iajs-3457	66	5	transfusion	transfusion	NOUN
iajs-3457	66	6	characteristics	characteristic	NOUN
iajs-3457	66	7	and	and	CCONJ
iajs-3457	66	8	durations	duration	NOUN
iajs-3457	66	9	.	.	PUNCT
iajs-3457	67	1	we	we	PRON
iajs-3457	67	2	used	use	VERB
iajs-3457	67	3	a	a	DET
iajs-3457	67	4	five	five	NUM
iajs-3457	67	5	-	-	PUNCT
iajs-3457	67	6	ml	ml	ADV
iajs-3457	67	7	disposable	disposable	ADJ
iajs-3457	67	8	syringe	syringe	NOUN
iajs-3457	67	9	to	to	PART
iajs-3457	67	10	collect	collect	VERB
iajs-3457	67	11	venous	venous	ADJ
iajs-3457	67	12	blood	blood	NOUN
iajs-3457	67	13	from	from	ADP
iajs-3457	67	14	all	all	DET
iajs-3457	67	15	the	the	DET
iajs-3457	67	16	patients	patient	NOUN
iajs-3457	67	17	through	through	ADP
iajs-3457	67	18	vein	vein	ADJ
iajs-3457	67	19	punctures	puncture	NOUN
iajs-3457	67	20	,	,	PUNCT
iajs-3457	67	21	dividing	divide	VERB
iajs-3457	67	22	it	it	PRON
iajs-3457	67	23	into	into	ADP
iajs-3457	67	24	two	two	NUM
iajs-3457	67	25	parts	part	NOUN
iajs-3457	67	26	:	:	PUNCT
iajs-3457	67	27	we	we	PRON
iajs-3457	67	28	transferred	transfer	VERB
iajs-3457	67	29	the	the	DET
iajs-3457	67	30	first	first	ADJ
iajs-3457	67	31	part	part	NOUN
iajs-3457	67	32	to	to	ADP
iajs-3457	67	33	an	an	DET
iajs-3457	67	34	edta	edta	NOUN
iajs-3457	67	35	tube	tube	NOUN
iajs-3457	67	36	for	for	ADP
iajs-3457	67	37	cbc	cbc	NOUN
iajs-3457	67	38	determination	determination	NOUN
iajs-3457	67	39	,	,	PUNCT
iajs-3457	67	40	and	and	CCONJ
iajs-3457	67	41	then	then	ADV
iajs-3457	67	42	moved	move	VERB
iajs-3457	67	43	the	the	DET
iajs-3457	67	44	second	second	ADJ
iajs-3457	67	45	part	part	NOUN
iajs-3457	67	46	to	to	ADP
iajs-3457	67	47	a	a	DET
iajs-3457	67	48	gel	gel	NOUN
iajs-3457	67	49	tube	tube	NOUN
iajs-3457	67	50	to	to	PART
iajs-3457	67	51	allow	allow	VERB
iajs-3457	67	52	it	it	PRON
iajs-3457	67	53	to	to	PART
iajs-3457	67	54	coagulate	coagulate	VERB
iajs-3457	67	55	.	.	PUNCT
iajs-3457	68	1	we	we	PRON
iajs-3457	68	2	spun	spin	VERB
iajs-3457	68	3	the	the	DET
iajs-3457	68	4	serum	serum	NOUN
iajs-3457	68	5	at	at	ADP
iajs-3457	68	6	3000	3000	NUM
iajs-3457	68	7	rpm	rpm	NOUN
iajs-3457	68	8	for	for	ADP
iajs-3457	68	9	10	10	NUM
iajs-3457	68	10	minutes	minute	NOUN
iajs-3457	68	11	to	to	PART
iajs-3457	68	12	determine	determine	VERB
iajs-3457	68	13	the	the	DET
iajs-3457	68	14	levels	level	NOUN
iajs-3457	68	15	of	of	ADP
iajs-3457	68	16	crp	crp	PROPN
iajs-3457	68	17	and	and	CCONJ
iajs-3457	68	18	ferritin	ferritin	PROPN
iajs-3457	68	19	.	.	PUNCT
iajs-3457	69	1	the	the	DET
iajs-3457	69	2	kit	kit	NOUN
iajs-3457	69	3	includes	include	VERB
iajs-3457	69	4	an	an	DET
iajs-3457	69	5	enzyme	enzyme	NOUN
iajs-3457	69	6	-	-	PUNCT
iajs-3457	69	7	linked	link	VERB
iajs-3457	69	8	immunosorbent	immunosorbent	NOUN
iajs-3457	69	9	assay	assay	PROPN
iajs-3457	69	10	(	(	PUNCT
iajs-3457	69	11	elisa	elisa	NOUN
iajs-3457	69	12	)	)	PUNCT
iajs-3457	69	13	for	for	ADP
iajs-3457	69	14	measuring	measure	VERB
iajs-3457	69	15	pro	pro	ADJ
iajs-3457	69	16	-	-	ADJ
iajs-3457	69	17	inflammatory	inflammatory	ADJ
iajs-3457	69	18	cytokines	cytokine	NOUN
iajs-3457	69	19	such	such	ADJ
iajs-3457	69	20	as	as	ADP
iajs-3457	69	21	il-1	il-1	NUM
iajs-3457	69	22	and	and	CCONJ
iajs-3457	69	23	il-6	il-6	PRON
iajs-3457	69	24	.	.	PUNCT
iajs-3457	70	1	this	this	DET
iajs-3457	70	2	method	method	NOUN
iajs-3457	70	3	is	be	AUX
iajs-3457	70	4	"	"	PUNCT
iajs-3457	70	5	based	base	VERB
iajs-3457	70	6	on	on	ADP
iajs-3457	70	7	biotin	biotin	NOUN
iajs-3457	70	8	double	double	ADJ
iajs-3457	70	9	antibody	antibody	NOUN
iajs-3457	70	10	sandwich	sandwich	NOUN
iajs-3457	70	11	technology	technology	NOUN
iajs-3457	70	12	.	.	PUNCT
iajs-3457	70	13	"	"	PUNCT
iajs-3457	71	1	we	we	PRON
iajs-3457	71	2	stored	store	VERB
iajs-3457	71	3	the	the	DET
iajs-3457	71	4	samples	sample	NOUN
iajs-3457	71	5	at	at	ADP
iajs-3457	71	6	20	20	NUM
iajs-3457	71	7	°	°	NOUN
iajs-3457	71	8	c	c	NOUN
iajs-3457	71	9	prior	prior	ADV
iajs-3457	71	10	to	to	ADP
iajs-3457	71	11	analysis	analysis	NOUN
iajs-3457	71	12	.	.	PUNCT
iajs-3457	72	1	ihjpas	ihjpas	PROPN
iajs-3457	72	2	.	.	PUNCT
iajs-3457	73	1	2024	2024	NUM
iajs-3457	73	2	,	,	PUNCT
iajs-3457	73	3	37(4	37(4	NOUN
iajs-3457	73	4	)	)	PUNCT
iajs-3457	73	5	38	38	NUM
iajs-3457	73	6	3	3	NUM
iajs-3457	73	7	.	.	PUNCT
iajs-3457	73	8	results	result	NOUN
iajs-3457	73	9	and	and	CCONJ
iajs-3457	73	10	discussion	discussion	VERB
iajs-3457	73	11	the	the	DET
iajs-3457	73	12	results	result	NOUN
iajs-3457	73	13	of	of	ADP
iajs-3457	73	14	this	this	DET
iajs-3457	73	15	study	study	NOUN
iajs-3457	73	16	showed	show	VERB
iajs-3457	73	17	that	that	SCONJ
iajs-3457	73	18	there	there	PRON
iajs-3457	73	19	is	be	VERB
iajs-3457	73	20	no	no	DET
iajs-3457	73	21	significant	significant	ADJ
iajs-3457	73	22	(	(	PUNCT
iajs-3457	73	23	p>0.01	p>0.01	PROPN
iajs-3457	73	24	)	)	PUNCT
iajs-3457	73	25	difference	difference	NOUN
iajs-3457	73	26	in	in	ADP
iajs-3457	73	27	age	age	NOUN
iajs-3457	73	28	between	between	ADP
iajs-3457	73	29	patients	patient	NOUN
iajs-3457	73	30	with	with	ADP
iajs-3457	73	31	β	β	X
iajs-3457	73	32	-	-	PUNCT
iajs-3457	73	33	thalassemia	thalassemia	ADJ
iajs-3457	73	34	major	major	NOUN
iajs-3457	73	35	(	(	PUNCT
iajs-3457	73	36	19.38	19.38	NUM
iajs-3457	73	37	±0.85	±0.85	NOUN
iajs-3457	73	38	)	)	PUNCT
iajs-3457	73	39	years	year	NOUN
iajs-3457	73	40	and	and	CCONJ
iajs-3457	73	41	controls	control	NOUN
iajs-3457	73	42	(	(	PUNCT
iajs-3457	73	43	21.70	21.70	NUM
iajs-3457	73	44	±0.77	±0.77	ADJ
iajs-3457	73	45	)	)	PUNCT
iajs-3457	73	46	years	year	NOUN
iajs-3457	73	47	.	.	PUNCT
iajs-3457	74	1	the	the	DET
iajs-3457	74	2	study	study	NOUN
iajs-3457	74	3	found	find	VERB
iajs-3457	74	4	that	that	SCONJ
iajs-3457	74	5	people	people	NOUN
iajs-3457	74	6	with	with	ADP
iajs-3457	74	7	b	b	NOUN
iajs-3457	74	8	-	-	PUNCT
iajs-3457	74	9	thalassemia	thalassemia	NOUN
iajs-3457	74	10	had	have	VERB
iajs-3457	74	11	significantly	significantly	ADV
iajs-3457	74	12	lower	low	ADJ
iajs-3457	74	13	mean	mean	PROPN
iajs-3457	74	14	rbc	rbc	PROPN
iajs-3457	74	15	and	and	CCONJ
iajs-3457	74	16	hb	hb	PROPN
iajs-3457	74	17	levels	level	NOUN
iajs-3457	74	18	(	(	PUNCT
iajs-3457	74	19	4.77	4.77	NUM
iajs-3457	74	20	±0.07	±0.07	NOUN
iajs-3457	74	21	106/µl	106/µl	NUM
iajs-3457	74	22	and	and	CCONJ
iajs-3457	74	23	14.06	14.06	NUM
iajs-3457	74	24	±0.24	±0.24	NOUN
iajs-3457	74	25	g	g	PROPN
iajs-3457	74	26	/	/	SYM
iajs-3457	74	27	dl	dl	NOUN
iajs-3457	74	28	)	)	PUNCT
iajs-3457	74	29	than	than	ADP
iajs-3457	74	30	healthy	healthy	ADJ
iajs-3457	74	31	controls	control	NOUN
iajs-3457	74	32	(	(	PUNCT
iajs-3457	74	33	p≤0.01	p≤0.01	NOUN
iajs-3457	74	34	)	)	PUNCT
iajs-3457	74	35	.	.	PUNCT
iajs-3457	75	1	however	however	ADV
iajs-3457	75	2	,	,	PUNCT
iajs-3457	75	3	table	table	NOUN
iajs-3457	75	4	1	1	NUM
iajs-3457	75	5	shows	show	VERB
iajs-3457	75	6	that	that	SCONJ
iajs-3457	75	7	the	the	DET
iajs-3457	75	8	mean	mean	ADJ
iajs-3457	75	9	plt	plt	NOUN
iajs-3457	75	10	levels	level	NOUN
iajs-3457	75	11	were	be	AUX
iajs-3457	75	12	significantly	significantly	ADV
iajs-3457	75	13	higher	high	ADJ
iajs-3457	75	14	(	(	PUNCT
iajs-3457	75	15	p≤0.01	p≤0.01	NOUN
iajs-3457	75	16	)	)	PUNCT
iajs-3457	75	17	in	in	ADP
iajs-3457	75	18	people	people	NOUN
iajs-3457	75	19	with	with	ADP
iajs-3457	75	20	β	β	NOUN
iajs-3457	75	21	-	-	NOUN
iajs-3457	75	22	thalassemia	thalassemia	NOUN
iajs-3457	75	23	(	(	PUNCT
iajs-3457	75	24	384.59	384.59	NUM
iajs-3457	75	25	±21.67	±21.67	NOUN
iajs-3457	75	26	103/µl	103/µl	NUM
iajs-3457	75	27	)	)	PUNCT
iajs-3457	75	28	compared	compare	VERB
iajs-3457	75	29	to	to	ADP
iajs-3457	75	30	healthy	healthy	ADJ
iajs-3457	75	31	people	people	NOUN
iajs-3457	75	32	(	(	PUNCT
iajs-3457	75	33	224.06	224.06	NUM
iajs-3457	75	34	±6.23	±6.23	PROPN
iajs-3457	75	35	103/µl	103/µl	NUM
iajs-3457	75	36	)	)	PUNCT
iajs-3457	75	37	.	.	PUNCT
iajs-3457	76	1	table	table	NOUN
iajs-3457	76	2	1	1	NUM
iajs-3457	76	3	.	.	X
iajs-3457	76	4	age	age	NOUN
iajs-3457	76	5	and	and	CCONJ
iajs-3457	76	6	blood	blood	NOUN
iajs-3457	76	7	parameters	parameter	NOUN
iajs-3457	76	8	value	value	VERB
iajs-3457	76	9	in	in	ADP
iajs-3457	76	10	β	β	NOUN
iajs-3457	76	11	-	-	ADJ
iajs-3457	76	12	thalassemia	thalassemia	VERB
iajs-3457	76	13	major	major	ADJ
iajs-3457	76	14	patients	patient	NOUN
iajs-3457	76	15	and	and	CCONJ
iajs-3457	76	16	control	control	NOUN
iajs-3457	76	17	.	.	PUNCT
iajs-3457	77	1	group	group	NOUN
iajs-3457	77	2	mean	mean	VERB
iajs-3457	77	3	±	±	PROPN
iajs-3457	77	4	se	se	PROPN
iajs-3457	77	5	age	age	PROPN
iajs-3457	77	6	(	(	PUNCT
iajs-3457	77	7	year	year	NOUN
iajs-3457	77	8	)	)	PUNCT
iajs-3457	77	9	rbc	rbc	PROPN
iajs-3457	77	10	(	(	PUNCT
iajs-3457	77	11	106/µl	106/µl	NUM
iajs-3457	77	12	)	)	PUNCT
iajs-3457	77	13	hb	hb	X
iajs-3457	77	14	(	(	PUNCT
iajs-3457	77	15	g	g	PROPN
iajs-3457	77	16	/	/	SYM
iajs-3457	77	17	dl	dl	NOUN
iajs-3457	77	18	)	)	PUNCT
iajs-3457	77	19	plt	plt	NOUN
iajs-3457	77	20	(	(	PUNCT
iajs-3457	77	21	10	10	NUM
iajs-3457	77	22	^	^	SYM
iajs-3457	77	23	3/µl	3/µl	NUM
iajs-3457	77	24	)	)	PUNCT
iajs-3457	77	25	patients	patient	NOUN
iajs-3457	77	26	19.38	19.38	NUM
iajs-3457	77	27	±0.85	±0.85	NOUN
iajs-3457	77	28	3.03	3.03	NUM
iajs-3457	77	29	±0.06	±0.06	PROPN
iajs-3457	77	30	8.01	8.01	NUM
iajs-3457	77	31	±0.17	±0.17	PROPN
iajs-3457	77	32	384.59	384.59	NUM
iajs-3457	77	33	±21.67	±21.67	NOUN
iajs-3457	77	34	control	control	NOUN
iajs-3457	77	35	21.70	21.70	NUM
iajs-3457	77	36	±0.77	±0.77	PROPN
iajs-3457	77	37	4.77	4.77	NUM
iajs-3457	77	38	±0.07	±0.07	PROPN
iajs-3457	77	39	14.06	14.06	NUM
iajs-3457	77	40	±0.24	±0.24	NOUN
iajs-3457	77	41	224.06	224.06	NUM
iajs-3457	77	42	±6.23	±6.23	PROPN
iajs-3457	77	43	t	t	PROPN
iajs-3457	77	44	-	-	PUNCT
iajs-3457	77	45	test	test	NOUN
iajs-3457	77	46	2.640	2.640	NUM
iajs-3457	77	47	*	*	PUNCT
iajs-3457	77	48	*	*	PUNCT
iajs-3457	77	49	0.194	0.194	NUM
iajs-3457	77	50	*	*	PUNCT
iajs-3457	77	51	*	*	PUNCT
iajs-3457	77	52	0.603	0.603	NUM
iajs-3457	77	53	*	*	PUNCT
iajs-3457	77	54	*	*	PUNCT
iajs-3457	77	55	61.716	61.716	NUM
iajs-3457	77	56	*	*	PUNCT
iajs-3457	77	57	*	*	PUNCT
iajs-3457	77	58	p	p	X
iajs-3457	77	59	-	-	PUNCT
iajs-3457	77	60	value	value	NOUN
iajs-3457	77	61	ns	ns	NUM
iajs-3457	77	62	0.0001	0.0001	NUM
iajs-3457	77	63	0.0001	0.0001	NUM
iajs-3457	77	64	0.0001	0.0001	NUM
iajs-3457	77	65	*	*	PUNCT
iajs-3457	77	66	*	*	PUNCT
iajs-3457	77	67	(	(	PUNCT
iajs-3457	77	68	p≤0.01	p≤0.01	NOUN
iajs-3457	77	69	)	)	PUNCT
iajs-3457	77	70	,	,	PUNCT
iajs-3457	77	71	ns	ns	CCONJ
iajs-3457	77	72	this	this	DET
iajs-3457	77	73	study	study	NOUN
iajs-3457	77	74	showed	show	VERB
iajs-3457	77	75	that	that	SCONJ
iajs-3457	77	76	there	there	PRON
iajs-3457	77	77	was	be	VERB
iajs-3457	77	78	no	no	DET
iajs-3457	77	79	significant	significant	ADJ
iajs-3457	77	80	difference	difference	NOUN
iajs-3457	77	81	between	between	ADP
iajs-3457	77	82	the	the	DET
iajs-3457	77	83	selected	select	VERB
iajs-3457	77	84	age	age	NOUN
iajs-3457	77	85	groups	group	NOUN
iajs-3457	77	86	.	.	PUNCT
iajs-3457	78	1	the	the	DET
iajs-3457	78	2	explanation	explanation	NOUN
iajs-3457	78	3	for	for	ADP
iajs-3457	78	4	this	this	DET
iajs-3457	78	5	result	result	NOUN
iajs-3457	78	6	may	may	AUX
iajs-3457	78	7	be	be	AUX
iajs-3457	78	8	due	due	ADJ
iajs-3457	78	9	to	to	ADP
iajs-3457	78	10	the	the	DET
iajs-3457	78	11	selection	selection	NOUN
iajs-3457	78	12	of	of	ADP
iajs-3457	78	13	samples	sample	NOUN
iajs-3457	78	14	.	.	PUNCT
iajs-3457	79	1	in	in	ADP
iajs-3457	79	2	the	the	DET
iajs-3457	79	3	past	past	ADJ
iajs-3457	79	4	three	three	NUM
iajs-3457	79	5	years	year	NOUN
iajs-3457	79	6	,	,	PUNCT
iajs-3457	79	7	there	there	PRON
iajs-3457	79	8	has	have	AUX
iajs-3457	79	9	been	be	AUX
iajs-3457	79	10	a	a	DET
iajs-3457	79	11	significant	significant	ADJ
iajs-3457	79	12	change	change	NOUN
iajs-3457	79	13	in	in	ADP
iajs-3457	79	14	the	the	DET
iajs-3457	79	15	normal	normal	ADJ
iajs-3457	79	16	course	course	NOUN
iajs-3457	79	17	of	of	ADP
iajs-3457	79	18	β	β	NOUN
iajs-3457	79	19	-	-	NOUN
iajs-3457	79	20	thalassemia	thalassemia	NOUN
iajs-3457	79	21	,	,	PUNCT
iajs-3457	79	22	and	and	CCONJ
iajs-3457	79	23	a	a	DET
iajs-3457	79	24	sizable	sizable	ADJ
iajs-3457	79	25	community	community	NOUN
iajs-3457	79	26	of	of	ADP
iajs-3457	79	27	patients	patient	NOUN
iajs-3457	79	28	who	who	PRON
iajs-3457	79	29	are	be	AUX
iajs-3457	79	30	over	over	ADP
iajs-3457	79	31	40	40	NUM
iajs-3457	79	32	years	year	NOUN
iajs-3457	79	33	old	old	ADJ
iajs-3457	79	34	is	be	AUX
iajs-3457	79	35	now	now	ADV
iajs-3457	79	36	present	present	ADJ
iajs-3457	79	37	[	[	X
iajs-3457	79	38	24	24	NUM
iajs-3457	79	39	]	]	PUNCT
iajs-3457	79	40	.	.	PUNCT
iajs-3457	80	1	academic	academic	ADJ
iajs-3457	80	2	scholars	scholar	NOUN
iajs-3457	80	3	have	have	AUX
iajs-3457	80	4	already	already	ADV
iajs-3457	80	5	expressed	express	VERB
iajs-3457	80	6	interest	interest	NOUN
iajs-3457	80	7	in	in	ADP
iajs-3457	80	8	beta	beta	NOUN
iajs-3457	80	9	-	-	PUNCT
iajs-3457	80	10	thalassemia	thalassemia	NOUN
iajs-3457	80	11	,	,	PUNCT
iajs-3457	80	12	one	one	NUM
iajs-3457	80	13	of	of	ADP
iajs-3457	80	14	asia	asia	PROPN
iajs-3457	80	15	's	's	PART
iajs-3457	80	16	most	most	ADV
iajs-3457	80	17	common	common	ADJ
iajs-3457	80	18	genetic	genetic	ADJ
iajs-3457	80	19	diseases	disease	NOUN
iajs-3457	80	20	and	and	CCONJ
iajs-3457	80	21	the	the	DET
iajs-3457	80	22	majority	majority	NOUN
iajs-3457	80	23	of	of	ADP
iajs-3457	80	24	the	the	DET
iajs-3457	80	25	world	world	NOUN
iajs-3457	80	26	.	.	PUNCT
iajs-3457	81	1	thalassemia	thalassemia	NOUN
iajs-3457	81	2	syndromes	syndrome	NOUN
iajs-3457	81	3	are	be	AUX
iajs-3457	81	4	a	a	DET
iajs-3457	81	5	group	group	NOUN
iajs-3457	81	6	of	of	ADP
iajs-3457	81	7	serious	serious	ADJ
iajs-3457	81	8	genetic	genetic	ADJ
iajs-3457	81	9	disorders	disorder	NOUN
iajs-3457	81	10	that	that	PRON
iajs-3457	81	11	develop	develop	VERB
iajs-3457	81	12	in	in	ADP
iajs-3457	81	13	children	child	NOUN
iajs-3457	81	14	and	and	CCONJ
iajs-3457	81	15	adolescents	adolescent	NOUN
iajs-3457	81	16	when	when	SCONJ
iajs-3457	81	17	one	one	NUM
iajs-3457	81	18	of	of	ADP
iajs-3457	81	19	the	the	DET
iajs-3457	81	20	thalassemia	thalassemia	NOUN
iajs-3457	81	21	or	or	CCONJ
iajs-3457	81	22	hemoglobin	hemoglobin	NOUN
iajs-3457	81	23	lepore	lepore	NOUN
iajs-3457	81	24	genes	gene	NOUN
iajs-3457	81	25	is	be	AUX
iajs-3457	81	26	homozygous	homozygous	ADJ
iajs-3457	81	27	[	[	X
iajs-3457	81	28	25	25	NUM
iajs-3457	81	29	]	]	PUNCT
iajs-3457	81	30	.	.	PUNCT
iajs-3457	82	1	the	the	DET
iajs-3457	82	2	quantity	quantity	NOUN
iajs-3457	82	3	of	of	ADP
iajs-3457	82	4	red	red	ADJ
iajs-3457	82	5	blood	blood	NOUN
iajs-3457	82	6	cells	cell	NOUN
iajs-3457	82	7	was	be	AUX
iajs-3457	82	8	low	low	ADJ
iajs-3457	82	9	in	in	ADP
iajs-3457	82	10	the	the	DET
iajs-3457	82	11	present	present	ADJ
iajs-3457	82	12	study	study	NOUN
iajs-3457	82	13	,	,	PUNCT
iajs-3457	82	14	and	and	CCONJ
iajs-3457	82	15	the	the	DET
iajs-3457	82	16	hb	hb	PROPN
iajs-3457	82	17	result	result	NOUN
iajs-3457	82	18	was	be	AUX
iajs-3457	82	19	comparable	comparable	ADJ
iajs-3457	82	20	to	to	ADP
iajs-3457	82	21	that	that	PRON
iajs-3457	82	22	of	of	ADP
iajs-3457	82	23	[	[	X
iajs-3457	82	24	26	26	NUM
iajs-3457	82	25	]	]	PUNCT
iajs-3457	82	26	,	,	PUNCT
iajs-3457	82	27	who	who	PRON
iajs-3457	82	28	discovered	discover	VERB
iajs-3457	82	29	that	that	SCONJ
iajs-3457	82	30	the	the	DET
iajs-3457	82	31	btm	btm	PROPN
iajs-3457	82	32	group	group	NOUN
iajs-3457	82	33	's	's	PART
iajs-3457	82	34	mean	mean	ADJ
iajs-3457	82	35	values	value	NOUN
iajs-3457	82	36	for	for	ADP
iajs-3457	82	37	all	all	DET
iajs-3457	82	38	rbc	rbc	PROPN
iajs-3457	82	39	parameters	parameter	NOUN
iajs-3457	82	40	(	(	PUNCT
iajs-3457	82	41	mcv	mcv	PROPN
iajs-3457	82	42	,	,	PUNCT
iajs-3457	82	43	mchc	mchc	NOUN
iajs-3457	82	44	,	,	PUNCT
iajs-3457	82	45	mch	mch	PROPN
iajs-3457	82	46	,	,	PUNCT
iajs-3457	82	47	hct	hct	PROPN
iajs-3457	82	48	,	,	PUNCT
iajs-3457	82	49	and	and	CCONJ
iajs-3457	82	50	hb	hb	NOUN
iajs-3457	82	51	)	)	PUNCT
iajs-3457	82	52	were	be	AUX
iajs-3457	82	53	lower	low	ADJ
iajs-3457	82	54	than	than	ADP
iajs-3457	82	55	those	those	PRON
iajs-3457	82	56	of	of	ADP
iajs-3457	82	57	the	the	DET
iajs-3457	82	58	control	control	NOUN
iajs-3457	82	59	group	group	NOUN
iajs-3457	82	60	.	.	PUNCT
iajs-3457	83	1	noteworthy	noteworthy	ADJ
iajs-3457	83	2	is	be	AUX
iajs-3457	83	3	that	that	SCONJ
iajs-3457	83	4	[	[	X
iajs-3457	83	5	27	27	NUM
iajs-3457	83	6	]	]	PUNCT
iajs-3457	83	7	discovered	discover	VERB
iajs-3457	83	8	that	that	SCONJ
iajs-3457	83	9	rbc	rbc	PROPN
iajs-3457	83	10	in	in	ADP
iajs-3457	83	11	thalassemia	thalassemia	NOUN
iajs-3457	83	12	patients	patient	NOUN
iajs-3457	83	13	exhibits	exhibit	VERB
iajs-3457	83	14	a	a	DET
iajs-3457	83	15	significant	significant	ADJ
iajs-3457	83	16	deficiency	deficiency	NOUN
iajs-3457	83	17	in	in	ADP
iajs-3457	83	18	hemoglobin	hemoglobin	NOUN
iajs-3457	83	19	chains	chain	NOUN
iajs-3457	83	20	,	,	PUNCT
iajs-3457	83	21	either	either	CCONJ
iajs-3457	83	22	being	be	AUX
iajs-3457	83	23	absent	absent	ADJ
iajs-3457	83	24	of	of	ADP
iajs-3457	83	25	hemoglobin	hemoglobin	NOUN
iajs-3457	83	26	β	β	PROPN
iajs-3457	83	27	or	or	CCONJ
iajs-3457	83	28	carrying	carry	VERB
iajs-3457	83	29	beta	beta	NOUN
iajs-3457	83	30	chains	chain	NOUN
iajs-3457	83	31	but	but	CCONJ
iajs-3457	83	32	lacking	lack	VERB
iajs-3457	83	33	in	in	ADP
iajs-3457	83	34	+	+	ADJ
iajs-3457	83	35	β	β	NOUN
iajs-3457	83	36	production	production	NOUN
iajs-3457	83	37	.	.	PUNCT
iajs-3457	84	1	this	this	PRON
iajs-3457	84	2	often	often	ADV
iajs-3457	84	3	occurs	occur	VERB
iajs-3457	84	4	during	during	ADP
iajs-3457	84	5	the	the	DET
iajs-3457	84	6	erythropoiesis	erythropoiesis	NOUN
iajs-3457	84	7	formation	formation	NOUN
iajs-3457	84	8	stage	stage	NOUN
iajs-3457	84	9	,	,	PUNCT
iajs-3457	84	10	which	which	PRON
iajs-3457	84	11	encompasses	encompass	VERB
iajs-3457	84	12	numerous	numerous	ADJ
iajs-3457	84	13	stages	stage	NOUN
iajs-3457	84	14	,	,	PUNCT
iajs-3457	84	15	the	the	DET
iajs-3457	84	16	most	most	ADV
iajs-3457	84	17	notable	notable	ADJ
iajs-3457	84	18	of	of	ADP
iajs-3457	84	19	which	which	PRON
iajs-3457	84	20	is	be	AUX
iajs-3457	84	21	differentiation	differentiation	NOUN
iajs-3457	84	22	.	.	PUNCT
iajs-3457	85	1	erythropoiesis	erythropoiesis	NOUN
iajs-3457	85	2	is	be	AUX
iajs-3457	85	3	the	the	DET
iajs-3457	85	4	process	process	NOUN
iajs-3457	85	5	that	that	PRON
iajs-3457	85	6	creates	create	VERB
iajs-3457	85	7	rbc	rbc	PROPN
iajs-3457	85	8	from	from	ADP
iajs-3457	85	9	the	the	DET
iajs-3457	85	10	hematopoiesis	hematopoiesis	NOUN
iajs-3457	85	11	stem	stem	NOUN
iajs-3457	85	12	cell	cell	NOUN
iajs-3457	85	13	in	in	ADP
iajs-3457	85	14	the	the	DET
iajs-3457	85	15	bone	bone	NOUN
iajs-3457	85	16	marrow	marrow	NOUN
iajs-3457	85	17	.	.	PUNCT
iajs-3457	86	1	moreover	moreover	ADV
iajs-3457	86	2	,	,	PUNCT
iajs-3457	86	3	the	the	DET
iajs-3457	86	4	sovereignty	sovereignty	NOUN
iajs-3457	86	5	will	will	AUX
iajs-3457	86	6	be	be	AUX
iajs-3457	86	7	for	for	ADP
iajs-3457	86	8	α	α	NOUN
iajs-3457	86	9	-	-	PUNCT
iajs-3457	86	10	type	type	NOUN
iajs-3457	86	11	chains	chain	NOUN
iajs-3457	86	12	in	in	ADP
iajs-3457	86	13	both	both	DET
iajs-3457	86	14	circumstances	circumstance	NOUN
iajs-3457	86	15	(	(	PUNCT
iajs-3457	86	16	β0	β0	NOUN
iajs-3457	86	17	or	or	CCONJ
iajs-3457	86	18	β+	β+	NUM
iajs-3457	86	19	)	)	PUNCT
iajs-3457	86	20	,	,	PUNCT
iajs-3457	86	21	meaning	mean	VERB
iajs-3457	86	22	that	that	SCONJ
iajs-3457	86	23	productivity	productivity	NOUN
iajs-3457	86	24	will	will	AUX
iajs-3457	86	25	favor	favor	VERB
iajs-3457	86	26	alpha	alpha	ADV
iajs-3457	86	27	over	over	ADP
iajs-3457	86	28	beta	beta	NOUN
iajs-3457	86	29	.	.	PUNCT
iajs-3457	87	1	red	red	ADJ
iajs-3457	87	2	blood	blood	NOUN
iajs-3457	87	3	cells	cell	NOUN
iajs-3457	87	4	will	will	AUX
iajs-3457	87	5	undoubtedly	undoubtedly	ADV
iajs-3457	87	6	acquire	acquire	VERB
iajs-3457	87	7	these	these	DET
iajs-3457	87	8	excess	excess	ADJ
iajs-3457	87	9	alpha	alpha	NOUN
iajs-3457	87	10	chains	chain	NOUN
iajs-3457	87	11	,	,	PUNCT
iajs-3457	87	12	resulting	result	VERB
iajs-3457	87	13	in	in	ADP
iajs-3457	87	14	uneven	uneven	ADJ
iajs-3457	87	15	red	red	ADJ
iajs-3457	87	16	blood	blood	NOUN
iajs-3457	87	17	cells	cell	NOUN
iajs-3457	87	18	that	that	PRON
iajs-3457	87	19	are	be	AUX
iajs-3457	87	20	unable	unable	ADJ
iajs-3457	87	21	to	to	PART
iajs-3457	87	22	transport	transport	VERB
iajs-3457	87	23	a	a	DET
iajs-3457	87	24	lot	lot	NOUN
iajs-3457	87	25	of	of	ADP
iajs-3457	87	26	oxygen	oxygen	NOUN
iajs-3457	87	27	throughout	throughout	ADP
iajs-3457	87	28	the	the	DET
iajs-3457	87	29	body	body	NOUN
iajs-3457	87	30	[	[	X
iajs-3457	87	31	28	28	NUM
iajs-3457	87	32	]	]	PUNCT
iajs-3457	87	33	.	.	PUNCT
iajs-3457	88	1	one	one	NUM
iajs-3457	88	2	of	of	ADP
iajs-3457	88	3	the	the	DET
iajs-3457	88	4	study	study	NOUN
iajs-3457	88	5	's	's	PART
iajs-3457	88	6	most	most	ADV
iajs-3457	88	7	significant	significant	ADJ
iajs-3457	88	8	findings	finding	NOUN
iajs-3457	88	9	is	be	AUX
iajs-3457	88	10	that	that	SCONJ
iajs-3457	88	11	hemoglobin	hemoglobin	NOUN
iajs-3457	88	12	chain	chain	NOUN
iajs-3457	88	13	imbalances	imbalance	NOUN
iajs-3457	88	14	cause	cause	VERB
iajs-3457	88	15	red	red	ADJ
iajs-3457	88	16	blood	blood	NOUN
iajs-3457	88	17	cells	cell	NOUN
iajs-3457	88	18	to	to	PART
iajs-3457	88	19	die	die	VERB
iajs-3457	88	20	quickly—120	quickly—120	ADJ
iajs-3457	88	21	days	day	NOUN
iajs-3457	88	22	sooner	soon	ADV
iajs-3457	88	23	than	than	SCONJ
iajs-3457	88	24	they	they	PRON
iajs-3457	88	25	would	would	AUX
iajs-3457	88	26	normally	normally	ADV
iajs-3457	88	27	do	do	VERB
iajs-3457	88	28	.	.	PUNCT
iajs-3457	89	1	this	this	PRON
iajs-3457	89	2	leaves	leave	VERB
iajs-3457	89	3	the	the	DET
iajs-3457	89	4	bone	bone	NOUN
iajs-3457	89	5	marrow	marrow	NOUN
iajs-3457	89	6	unable	unable	ADJ
iajs-3457	89	7	to	to	PART
iajs-3457	89	8	replace	replace	VERB
iajs-3457	89	9	the	the	DET
iajs-3457	89	10	lost	lost	ADJ
iajs-3457	89	11	rbc	rbc	PROPN
iajs-3457	89	12	,	,	PUNCT
iajs-3457	89	13	which	which	PRON
iajs-3457	89	14	means	mean	VERB
iajs-3457	89	15	that	that	SCONJ
iajs-3457	89	16	compared	compare	VERB
iajs-3457	89	17	to	to	ADP
iajs-3457	89	18	newly	newly	ADV
iajs-3457	89	19	formed	form	VERB
iajs-3457	89	20	cells	cell	NOUN
iajs-3457	89	21	,	,	PUNCT
iajs-3457	89	22	the	the	DET
iajs-3457	89	23	damaged	damage	VERB
iajs-3457	89	24	cyst	cyst	NOUN
iajs-3457	89	25	of	of	ADP
iajs-3457	89	26	red	red	ADJ
iajs-3457	89	27	blood	blood	NOUN
iajs-3457	89	28	cells	cell	NOUN
iajs-3457	89	29	is	be	AUX
iajs-3457	89	30	higher	high	ADJ
iajs-3457	89	31	.	.	PUNCT
iajs-3457	90	1	we	we	PRON
iajs-3457	90	2	would	would	AUX
iajs-3457	90	3	have	have	VERB
iajs-3457	90	4	misshaped	misshaped	ADJ
iajs-3457	90	5	bones	bone	NOUN
iajs-3457	90	6	as	as	ADP
iajs-3457	90	7	a	a	DET
iajs-3457	90	8	result	result	NOUN
iajs-3457	90	9	of	of	ADP
iajs-3457	90	10	the	the	DET
iajs-3457	90	11	enhanced	enhance	VERB
iajs-3457	90	12	erythropoiesis	erythropoiesis	NOUN
iajs-3457	90	13	processes	process	NOUN
iajs-3457	90	14	and	and	CCONJ
iajs-3457	90	15	osteoporosis	osteoporosis	NOUN
iajs-3457	90	16	brought	bring	VERB
iajs-3457	90	17	on	on	ADP
iajs-3457	90	18	by	by	ADP
iajs-3457	90	19	the	the	DET
iajs-3457	90	20	double	double	ADJ
iajs-3457	90	21	-	-	PUNCT
iajs-3457	90	22	reactive	reactive	ADJ
iajs-3457	90	23	pellets	pellet	NOUN
iajs-3457	90	24	'	'	PART
iajs-3457	90	25	depletion	depletion	NOUN
iajs-3457	90	26	of	of	ADP
iajs-3457	90	27	spinal	spinal	ADJ
iajs-3457	90	28	cord	cord	NOUN
iajs-3457	90	29	components	component	NOUN
iajs-3457	90	30	[	[	X
iajs-3457	90	31	29	29	NUM
iajs-3457	90	32	]	]	PUNCT
iajs-3457	90	33	.	.	PUNCT
iajs-3457	91	1	in	in	ADP
iajs-3457	91	2	addition	addition	NOUN
iajs-3457	91	3	,	,	PUNCT
iajs-3457	91	4	the	the	DET
iajs-3457	91	5	current	current	ADJ
iajs-3457	91	6	study	study	NOUN
iajs-3457	91	7	is	be	AUX
iajs-3457	91	8	compatible	compatible	ADJ
iajs-3457	91	9	with	with	ADP
iajs-3457	91	10	[	[	X
iajs-3457	91	11	30	30	NUM
iajs-3457	91	12	]	]	PUNCT
iajs-3457	91	13	.	.	PUNCT
iajs-3457	92	1	patients	patient	NOUN
iajs-3457	92	2	with	with	ADP
iajs-3457	92	3	thalassemia	thalassemia	NOUN
iajs-3457	92	4	have	have	VERB
iajs-3457	92	5	considerably	considerably	ADV
iajs-3457	92	6	more	more	ADJ
iajs-3457	92	7	platelets	platelet	NOUN
iajs-3457	92	8	(	(	PUNCT
iajs-3457	92	9	plt	plt	NOUN
iajs-3457	92	10	)	)	PUNCT
iajs-3457	92	11	than	than	ADP
iajs-3457	92	12	individuals	individual	NOUN
iajs-3457	92	13	without	without	ADP
iajs-3457	92	14	thalassemia	thalassemia	NOUN
iajs-3457	92	15	.	.	PUNCT
iajs-3457	93	1	the	the	DET
iajs-3457	93	2	potential	potential	ADJ
iajs-3457	93	3	causes	cause	NOUN
iajs-3457	93	4	of	of	ADP
iajs-3457	93	5	these	these	DET
iajs-3457	93	6	patients	patient	NOUN
iajs-3457	93	7	'	'	PART
iajs-3457	93	8	elevated	elevated	ADJ
iajs-3457	93	9	platelet	platelet	NOUN
iajs-3457	93	10	counts	count	NOUN
iajs-3457	93	11	are	be	AUX
iajs-3457	93	12	the	the	DET
iajs-3457	93	13	expansion	expansion	NOUN
iajs-3457	93	14	and	and	CCONJ
iajs-3457	93	15	maturation	maturation	NOUN
iajs-3457	93	16	of	of	ADP
iajs-3457	93	17	marrow	marrow	PROPN
iajs-3457	93	18	mononuclear	mononuclear	PROPN
iajs-3457	93	19	cells	cell	NOUN
iajs-3457	93	20	to	to	PART
iajs-3457	93	21	produce	produce	VERB
iajs-3457	93	22	colony	colony	NOUN
iajs-3457	93	23	-	-	PUNCT
iajs-3457	93	24	forming	form	VERB
iajs-3457	93	25	unit	unit	NOUN
iajs-3457	93	26	megakaryocytes	megakaryocyte	NOUN
iajs-3457	93	27	(	(	PUNCT
iajs-3457	93	28	cfumeg	cfumeg	NOUN
iajs-3457	93	29	)	)	PUNCT
iajs-3457	93	30	.	.	PUNCT
iajs-3457	94	1	ihjpas	ihjpas	PROPN
iajs-3457	94	2	.	.	PUNCT
iajs-3457	95	1	2024	2024	NUM
iajs-3457	95	2	,	,	PUNCT
iajs-3457	95	3	37(4	37(4	PROPN
iajs-3457	95	4	)	)	PUNCT
iajs-3457	95	5	39	39	NUM
iajs-3457	95	6	as	as	SCONJ
iajs-3457	95	7	shown	show	VERB
iajs-3457	95	8	in	in	ADP
iajs-3457	95	9	table	table	NOUN
iajs-3457	95	10	2	2	NUM
iajs-3457	95	11	,	,	PUNCT
iajs-3457	95	12	ferritin	ferritin	ADJ
iajs-3457	95	13	and	and	CCONJ
iajs-3457	95	14	crp	crp	PROPN
iajs-3457	95	15	showed	show	VERB
iajs-3457	95	16	a	a	DET
iajs-3457	95	17	highly	highly	ADV
iajs-3457	95	18	(	(	PUNCT
iajs-3457	95	19	p≤0.01	p≤0.01	NOUN
iajs-3457	95	20	)	)	PUNCT
iajs-3457	95	21	significant	significant	ADJ
iajs-3457	95	22	increase	increase	NOUN
iajs-3457	95	23	in	in	ADP
iajs-3457	95	24	patients	patient	NOUN
iajs-3457	95	25	with	with	ADP
iajs-3457	95	26	β	β	NOUN
iajs-3457	95	27	-	-	NOUN
iajs-3457	95	28	thalassemia	thalassemia	NOUN
iajs-3457	95	29	(	(	PUNCT
iajs-3457	95	30	4910.15	4910.15	NUM
iajs-3457	95	31	±202.67	±202.67	VERB
iajs-3457	95	32	ng	ng	PROPN
iajs-3457	95	33	/	/	SYM
iajs-3457	95	34	ml	ml	PROPN
iajs-3457	95	35	and	and	CCONJ
iajs-3457	95	36	3.02	3.02	NUM
iajs-3457	95	37	±0.08	±0.08	PROPN
iajs-3457	95	38	µg	µg	ADV
iajs-3457	95	39	/	/	SYM
iajs-3457	95	40	ml	ml	NOUN
iajs-3457	95	41	)	)	PUNCT
iajs-3457	95	42	,	,	PUNCT
iajs-3457	95	43	respectively	respectively	ADV
iajs-3457	95	44	,	,	PUNCT
iajs-3457	95	45	as	as	SCONJ
iajs-3457	95	46	compared	compare	VERB
iajs-3457	95	47	with	with	ADP
iajs-3457	95	48	control	control	NOUN
iajs-3457	95	49	(	(	PUNCT
iajs-3457	95	50	284.91	284.91	NUM
iajs-3457	95	51	±16.78	±16.78	SYM
iajs-3457	95	52	ng	ng	PROPN
iajs-3457	95	53	/	/	SYM
iajs-3457	95	54	ml	ml	PROPN
iajs-3457	95	55	and	and	CCONJ
iajs-3457	95	56	1.178	1.178	NUM
iajs-3457	95	57	±0.03	±0.03	PROPN
iajs-3457	95	58	µg	µg	ADV
iajs-3457	95	59	/	/	SYM
iajs-3457	95	60	ml	ml	NOUN
iajs-3457	95	61	)	)	PUNCT
iajs-3457	95	62	,	,	PUNCT
iajs-3457	95	63	respectively	respectively	ADV
iajs-3457	95	64	.	.	PUNCT
iajs-3457	96	1	table	table	NOUN
iajs-3457	96	2	2	2	NUM
iajs-3457	96	3	.	.	X
iajs-3457	96	4	level	level	NOUN
iajs-3457	96	5	of	of	ADP
iajs-3457	96	6	ferritin	ferritin	ADJ
iajs-3457	96	7	and	and	CCONJ
iajs-3457	96	8	crp	crp	NOUN
iajs-3457	96	9	in	in	ADP
iajs-3457	96	10	βthalassemia	βthalassemia	ADJ
iajs-3457	96	11	major	major	ADJ
iajs-3457	96	12	patients	patient	NOUN
iajs-3457	96	13	and	and	CCONJ
iajs-3457	96	14	control	control	NOUN
iajs-3457	96	15	.	.	PUNCT
iajs-3457	97	1	group	group	NOUN
iajs-3457	97	2	mean	mean	VERB
iajs-3457	97	3	±	±	PROPN
iajs-3457	97	4	se	se	X
iajs-3457	97	5	ferritin	ferritin	PROPN
iajs-3457	97	6	(	(	PUNCT
iajs-3457	97	7	ng	ng	PROPN
iajs-3457	97	8	/	/	SYM
iajs-3457	97	9	ml	ml	PROPN
iajs-3457	97	10	)	)	PUNCT
iajs-3457	97	11	crp	crp	NOUN
iajs-3457	97	12	(	(	PUNCT
iajs-3457	97	13	µg	µg	NOUN
iajs-3457	97	14	/	/	SYM
iajs-3457	97	15	ml	ml	NOUN
iajs-3457	97	16	)	)	PUNCT
iajs-3457	97	17	patients	patient	NOUN
iajs-3457	97	18	4910.15	4910.15	NUM
iajs-3457	97	19	±202.67	±202.67	VERB
iajs-3457	97	20	3.02	3.02	NUM
iajs-3457	97	21	±0.08	±0.08	PROPN
iajs-3457	97	22	control	control	NOUN
iajs-3457	97	23	284.91	284.91	NUM
iajs-3457	97	24	±16.78	±16.78	ADP
iajs-3457	97	25	1.178	1.178	NUM
iajs-3457	97	26	±0.03	±0.03	PROPN
iajs-3457	97	27	t	t	PROPN
iajs-3457	97	28	-	-	PUNCT
iajs-3457	97	29	test	test	NOUN
iajs-3457	97	30	2.899	2.899	NUM
iajs-3457	97	31	*	*	PUNCT
iajs-3457	97	32	*	*	PUNCT
iajs-3457	97	33	0.245	0.245	NUM
iajs-3457	97	34	*	*	PUNCT
iajs-3457	97	35	*	*	PUNCT
iajs-3457	97	36	p	p	X
iajs-3457	97	37	-	-	PUNCT
iajs-3457	97	38	value	value	NOUN
iajs-3457	97	39	0.0001	0.0001	NUM
iajs-3457	97	40	0.0001	0.0001	NUM
iajs-3457	97	41	*	*	PUNCT
iajs-3457	97	42	*	*	PUNCT
iajs-3457	97	43	(	(	PUNCT
iajs-3457	97	44	p≤0.01	p≤0.01	NOUN
iajs-3457	97	45	)	)	PUNCT
iajs-3457	97	46	.	.	PUNCT
iajs-3457	98	1	the	the	DET
iajs-3457	98	2	study	study	NOUN
iajs-3457	98	3	found	find	VERB
iajs-3457	98	4	that	that	SCONJ
iajs-3457	98	5	ferritin	ferritin	ADJ
iajs-3457	98	6	levels	level	NOUN
iajs-3457	98	7	were	be	AUX
iajs-3457	98	8	significantly	significantly	ADV
iajs-3457	98	9	higher	high	ADJ
iajs-3457	98	10	(	(	PUNCT
iajs-3457	98	11	p≤0.01	p≤0.01	NOUN
iajs-3457	98	12	)	)	PUNCT
iajs-3457	98	13	in	in	ADP
iajs-3457	98	14	people	people	NOUN
iajs-3457	98	15	with	with	ADP
iajs-3457	98	16	βthalassemia	βthalassemia	NOUN
iajs-3457	98	17	compared	compare	VERB
iajs-3457	98	18	to	to	ADP
iajs-3457	98	19	controls	control	NOUN
iajs-3457	98	20	.	.	PUNCT
iajs-3457	99	1	this	this	DET
iajs-3457	99	2	finding	finding	NOUN
iajs-3457	99	3	was	be	AUX
iajs-3457	99	4	similar	similar	ADJ
iajs-3457	99	5	to	to	ADP
iajs-3457	99	6	what	what	PRON
iajs-3457	99	7	was	be	AUX
iajs-3457	99	8	found	find	VERB
iajs-3457	99	9	in	in	ADP
iajs-3457	99	10	[	[	X
iajs-3457	99	11	31	31	NUM
iajs-3457	99	12	]	]	PUNCT
iajs-3457	99	13	,	,	PUNCT
iajs-3457	99	14	which	which	PRON
iajs-3457	99	15	also	also	ADV
iajs-3457	99	16	found	find	VERB
iajs-3457	99	17	that	that	SCONJ
iajs-3457	99	18	the	the	DET
iajs-3457	99	19	percentage	percentage	NOUN
iajs-3457	99	20	of	of	ADP
iajs-3457	99	21	ferritin	ferritin	ADJ
iajs-3457	99	22	was	be	AUX
iajs-3457	99	23	statistically	statistically	ADV
iajs-3457	99	24	significant	significant	ADJ
iajs-3457	99	25	in	in	ADP
iajs-3457	99	26	people	people	NOUN
iajs-3457	99	27	with	with	ADP
iajs-3457	99	28	β	β	NOUN
iajs-3457	99	29	-	-	NOUN
iajs-3457	99	30	thalassemia	thalassemia	NOUN
iajs-3457	99	31	.	.	PUNCT
iajs-3457	100	1	furthermore	furthermore	ADV
iajs-3457	100	2	,	,	PUNCT
iajs-3457	100	3	[	[	X
iajs-3457	100	4	32	32	NUM
iajs-3457	100	5	]	]	PUNCT
iajs-3457	100	6	found	find	VERB
iajs-3457	100	7	that	that	SCONJ
iajs-3457	100	8	patients	patient	NOUN
iajs-3457	100	9	with	with	ADP
iajs-3457	100	10	b	b	NOUN
iajs-3457	100	11	-	-	PUNCT
iajs-3457	100	12	thalassemia	thalassemia	NOUN
iajs-3457	100	13	major	major	NOUN
iajs-3457	100	14	have	have	VERB
iajs-3457	100	15	a	a	DET
iajs-3457	100	16	high	high	ADJ
iajs-3457	100	17	level	level	NOUN
iajs-3457	100	18	of	of	ADP
iajs-3457	100	19	ferritin	ferritin	ADJ
iajs-3457	100	20	as	as	ADP
iajs-3457	100	21	a	a	DET
iajs-3457	100	22	result	result	NOUN
iajs-3457	100	23	of	of	ADP
iajs-3457	100	24	frequent	frequent	ADJ
iajs-3457	100	25	blood	blood	NOUN
iajs-3457	100	26	transfusions	transfusion	NOUN
iajs-3457	100	27	and	and	CCONJ
iajs-3457	100	28	iron	iron	NOUN
iajs-3457	100	29	overload	overload	NOUN
iajs-3457	100	30	.	.	PUNCT
iajs-3457	101	1	[	[	X
iajs-3457	101	2	33	33	NUM
iajs-3457	101	3	]	]	PUNCT
iajs-3457	101	4	also	also	ADV
iajs-3457	101	5	noticed	notice	VERB
iajs-3457	101	6	that	that	SCONJ
iajs-3457	101	7	the	the	DET
iajs-3457	101	8	serum	serum	NOUN
iajs-3457	101	9	ferritin	ferritin	PROPN
iajs-3457	101	10	concentration	concentration	NOUN
iajs-3457	101	11	dramatically	dramatically	ADV
iajs-3457	101	12	rose	rise	VERB
iajs-3457	101	13	as	as	SCONJ
iajs-3457	101	14	the	the	DET
iajs-3457	101	15	number	number	NOUN
iajs-3457	101	16	of	of	ADP
iajs-3457	101	17	blood	blood	NOUN
iajs-3457	101	18	transfusions	transfusion	NOUN
iajs-3457	101	19	increased	increase	VERB
iajs-3457	101	20	.	.	PUNCT
iajs-3457	102	1	iraqi	iraqi	ADJ
iajs-3457	102	2	patients	patient	NOUN
iajs-3457	102	3	'	'	PART
iajs-3457	102	4	significantly	significantly	ADV
iajs-3457	102	5	elevated	elevate	VERB
iajs-3457	102	6	ferritin	ferritin	ADJ
iajs-3457	102	7	and	and	CCONJ
iajs-3457	102	8	serum	serum	NOUN
iajs-3457	102	9	iron	iron	NOUN
iajs-3457	102	10	levels	level	NOUN
iajs-3457	102	11	suggested	suggest	VERB
iajs-3457	102	12	an	an	DET
iajs-3457	102	13	existing	exist	VERB
iajs-3457	102	14	iron	iron	NOUN
iajs-3457	102	15	excess	excess	NOUN
iajs-3457	102	16	.	.	PUNCT
iajs-3457	103	1	his	his	PRON
iajs-3457	103	2	elevated	elevated	ADJ
iajs-3457	103	3	ferritin	ferritin	ADJ
iajs-3457	103	4	level	level	NOUN
iajs-3457	103	5	is	be	AUX
iajs-3457	103	6	a	a	DET
iajs-3457	103	7	significant	significant	ADJ
iajs-3457	103	8	risk	risk	NOUN
iajs-3457	103	9	factor	factor	NOUN
iajs-3457	103	10	for	for	ADP
iajs-3457	103	11	myocardial	myocardial	ADJ
iajs-3457	103	12	infarction	infarction	NOUN
iajs-3457	103	13	.	.	PUNCT
iajs-3457	104	1	without	without	ADP
iajs-3457	104	2	chelation	chelation	NOUN
iajs-3457	104	3	therapy	therapy	NOUN
iajs-3457	104	4	,	,	PUNCT
iajs-3457	104	5	frequent	frequent	ADJ
iajs-3457	104	6	blood	blood	NOUN
iajs-3457	104	7	transfusions	transfusion	NOUN
iajs-3457	104	8	in	in	ADP
iajs-3457	104	9	β	β	NOUN
iajs-3457	104	10	-	-	NOUN
iajs-3457	104	11	thalassemia	thalassemia	NOUN
iajs-3457	104	12	cause	cause	NOUN
iajs-3457	104	13	iron	iron	NOUN
iajs-3457	104	14	overload	overload	NOUN
iajs-3457	104	15	,	,	PUNCT
iajs-3457	104	16	which	which	PRON
iajs-3457	104	17	results	result	VERB
iajs-3457	104	18	in	in	ADP
iajs-3457	104	19	splenomegaly	splenomegaly	ADJ
iajs-3457	104	20	and	and	CCONJ
iajs-3457	104	21	other	other	ADJ
iajs-3457	104	22	issues	issue	NOUN
iajs-3457	104	23	.	.	PUNCT
iajs-3457	105	1	they	they	PRON
iajs-3457	105	2	also	also	ADV
iajs-3457	105	3	affect	affect	VERB
iajs-3457	105	4	the	the	DET
iajs-3457	105	5	liver	liver	NOUN
iajs-3457	105	6	's	's	PART
iajs-3457	105	7	function	function	NOUN
iajs-3457	105	8	,	,	PUNCT
iajs-3457	105	9	which	which	PRON
iajs-3457	105	10	raises	raise	VERB
iajs-3457	105	11	the	the	DET
iajs-3457	105	12	risk	risk	NOUN
iajs-3457	105	13	of	of	ADP
iajs-3457	105	14	other	other	ADJ
iajs-3457	105	15	complications	complication	NOUN
iajs-3457	105	16	(	(	PUNCT
iajs-3457	105	17	gpt	gpt	NOUN
iajs-3457	105	18	,	,	PUNCT
iajs-3457	105	19	got	get	VERB
iajs-3457	105	20	)	)	PUNCT
iajs-3457	106	1	[	[	X
iajs-3457	106	2	34	34	NUM
iajs-3457	106	3	]	]	PUNCT
iajs-3457	106	4	.	.	PUNCT
iajs-3457	107	1	on	on	ADP
iajs-3457	107	2	the	the	DET
iajs-3457	107	3	other	other	ADJ
iajs-3457	107	4	hand	hand	NOUN
iajs-3457	107	5	,	,	PUNCT
iajs-3457	107	6	c	c	NOUN
iajs-3457	107	7	-	-	ADJ
iajs-3457	107	8	reactive	reactive	ADJ
iajs-3457	107	9	protein	protein	NOUN
iajs-3457	107	10	(	(	PUNCT
iajs-3457	107	11	crp	crp	NOUN
iajs-3457	107	12	)	)	PUNCT
iajs-3457	107	13	is	be	AUX
iajs-3457	107	14	primarily	primarily	ADV
iajs-3457	107	15	used	use	VERB
iajs-3457	107	16	as	as	ADP
iajs-3457	107	17	a	a	DET
iajs-3457	107	18	marker	marker	NOUN
iajs-3457	107	19	of	of	ADP
iajs-3457	107	20	infection	infection	NOUN
iajs-3457	107	21	and	and	CCONJ
iajs-3457	107	22	inflammation	inflammation	NOUN
iajs-3457	107	23	.	.	PUNCT
iajs-3457	108	1	we	we	PRON
iajs-3457	108	2	can	can	AUX
iajs-3457	108	3	measure	measure	VERB
iajs-3457	108	4	and	and	CCONJ
iajs-3457	108	5	plot	plot	NOUN
iajs-3457	108	6	crp	crp	PROPN
iajs-3457	108	7	readings	reading	VERB
iajs-3457	108	8	to	to	PART
iajs-3457	108	9	assess	assess	VERB
iajs-3457	108	10	the	the	DET
iajs-3457	108	11	progression	progression	NOUN
iajs-3457	108	12	of	of	ADP
iajs-3457	108	13	a	a	DET
iajs-3457	108	14	disease	disease	NOUN
iajs-3457	108	15	or	or	CCONJ
iajs-3457	108	16	the	the	DET
iajs-3457	108	17	efficacy	efficacy	NOUN
iajs-3457	108	18	of	of	ADP
iajs-3457	108	19	treatment	treatment	NOUN
iajs-3457	108	20	.	.	PUNCT
iajs-3457	109	1	[	[	X
iajs-3457	109	2	35	35	NUM
iajs-3457	109	3	]	]	PUNCT
iajs-3457	109	4	show	show	VERB
iajs-3457	109	5	that	that	SCONJ
iajs-3457	109	6	i	i	PRON
iajs-3457	109	7	m	m	VERB
iajs-3457	109	8	a	a	PROPN
iajs-3457	109	9	and	and	CCONJ
iajs-3457	109	10	crp	crp	NOUN
iajs-3457	109	11	were	be	AUX
iajs-3457	109	12	significantly	significantly	ADV
iajs-3457	109	13	higher	high	ADJ
iajs-3457	109	14	in	in	ADP
iajs-3457	109	15	the	the	DET
iajs-3457	109	16	betathalassemia	betathalassemia	NOUN
iajs-3457	109	17	group	group	NOUN
iajs-3457	109	18	compared	compare	VERB
iajs-3457	109	19	with	with	ADP
iajs-3457	109	20	the	the	DET
iajs-3457	109	21	control	control	NOUN
iajs-3457	109	22	;	;	PUNCT
iajs-3457	109	23	this	this	DET
iajs-3457	109	24	finding	finding	NOUN
iajs-3457	109	25	is	be	AUX
iajs-3457	109	26	consistent	consistent	ADJ
iajs-3457	109	27	with	with	ADP
iajs-3457	109	28	the	the	DET
iajs-3457	109	29	current	current	ADJ
iajs-3457	109	30	research	research	NOUN
iajs-3457	109	31	.	.	PUNCT
iajs-3457	110	1	accord	accord	NOUN
iajs-3457	110	2	ing	e	VERB
iajs-3457	110	3	to	to	ADP
iajs-3457	110	4	[	[	X
iajs-3457	110	5	36	36	NUM
iajs-3457	110	6	]	]	PUNCT
iajs-3457	110	7	,	,	PUNCT
iajs-3457	110	8	there	there	PRON
iajs-3457	110	9	was	be	VERB
iajs-3457	110	10	an	an	DET
iajs-3457	110	11	interesting	interesting	ADJ
iajs-3457	110	12	trend	trend	NOUN
iajs-3457	110	13	toward	toward	ADP
iajs-3457	110	14	higher	high	ADJ
iajs-3457	110	15	levels	level	NOUN
iajs-3457	110	16	of	of	ADP
iajs-3457	110	17	c	c	NOUN
iajs-3457	110	18	-	-	PUNCT
iajs-3457	110	19	reactive	reactive	ADJ
iajs-3457	110	20	protein	protein	NOUN
iajs-3457	110	21	in	in	ADP
iajs-3457	110	22	beta	beta	NOUN
iajs-3457	110	23	-	-	PUNCT
iajs-3457	110	24	thal	thal	NOUN
iajs-3457	110	25	/	/	SYM
iajs-3457	110	26	hbe	hbe	NOUN
iajs-3457	110	27	post	post	ADJ
iajs-3457	110	28	-	-	ADJ
iajs-3457	110	29	splenectomy	splenectomy	ADJ
iajs-3457	110	30	patients	patient	NOUN
iajs-3457	110	31	whose	whose	DET
iajs-3457	110	32	platelet	platelet	NOUN
iajs-3457	110	33	counts	count	NOUN
iajs-3457	110	34	were	be	AUX
iajs-3457	110	35	higher	high	ADJ
iajs-3457	110	36	.	.	PUNCT
iajs-3457	111	1	platelets	platelet	NOUN
iajs-3457	111	2	,	,	PUNCT
iajs-3457	111	3	or	or	CCONJ
iajs-3457	111	4	factors	factor	NOUN
iajs-3457	111	5	that	that	PRON
iajs-3457	111	6	control	control	VERB
iajs-3457	111	7	thrombopoiesis	thrombopoiesis	NOUN
iajs-3457	111	8	,	,	PUNCT
iajs-3457	111	9	appear	appear	VERB
iajs-3457	111	10	to	to	PART
iajs-3457	111	11	be	be	AUX
iajs-3457	111	12	involved	involve	VERB
iajs-3457	111	13	in	in	ADP
iajs-3457	111	14	the	the	DET
iajs-3457	111	15	population	population	NOUN
iajs-3457	111	16	's	's	PART
iajs-3457	111	17	high	high	ADJ
iajs-3457	111	18	serum	serum	NOUN
iajs-3457	111	19	c	c	NOUN
iajs-3457	111	20	-	-	ADJ
iajs-3457	111	21	reactive	reactive	ADJ
iajs-3457	111	22	protein	protein	NOUN
iajs-3457	111	23	levels	level	NOUN
iajs-3457	111	24	.	.	PUNCT
iajs-3457	112	1	scientists	scientist	NOUN
iajs-3457	112	2	have	have	AUX
iajs-3457	112	3	used	use	VERB
iajs-3457	112	4	c	c	NOUN
iajs-3457	112	5	-	-	PUNCT
iajs-3457	112	6	reactive	reactive	ADJ
iajs-3457	112	7	proteins	protein	NOUN
iajs-3457	112	8	and	and	CCONJ
iajs-3457	112	9	cytokines	cytokine	NOUN
iajs-3457	112	10	to	to	PART
iajs-3457	112	11	find	find	VERB
iajs-3457	112	12	signs	sign	NOUN
iajs-3457	112	13	of	of	ADP
iajs-3457	112	14	inflammation	inflammation	NOUN
iajs-3457	112	15	in	in	ADP
iajs-3457	112	16	people	people	NOUN
iajs-3457	112	17	with	with	ADP
iajs-3457	112	18	thalassemia	thalassemia	NOUN
iajs-3457	112	19	and	and	CCONJ
iajs-3457	112	20	other	other	ADJ
iajs-3457	112	21	illnesses	illness	NOUN
iajs-3457	112	22	,	,	PUNCT
iajs-3457	112	23	such	such	ADJ
iajs-3457	112	24	as	as	ADP
iajs-3457	112	25	pneumonia	pneumonia	NOUN
iajs-3457	112	26	,	,	PUNCT
iajs-3457	112	27	an	an	DET
iajs-3457	112	28	infection	infection	NOUN
iajs-3457	112	29	that	that	PRON
iajs-3457	112	30	makes	make	VERB
iajs-3457	112	31	cystic	cystic	ADJ
iajs-3457	112	32	fibrosis	fibrosis	NOUN
iajs-3457	112	33	,	,	PUNCT
iajs-3457	112	34	diabetes	diabetes	NOUN
iajs-3457	112	35	,	,	PUNCT
iajs-3457	112	36	and	and	CCONJ
iajs-3457	112	37	hepatitis	hepatitis	NOUN
iajs-3457	112	38	worse	bad	ADJ
iajs-3457	112	39	,	,	PUNCT
iajs-3457	112	40	and	and	CCONJ
iajs-3457	112	41	to	to	PART
iajs-3457	112	42	see	see	VERB
iajs-3457	112	43	when	when	SCONJ
iajs-3457	112	44	heart	heart	NOUN
iajs-3457	112	45	problems	problem	NOUN
iajs-3457	112	46	are	be	AUX
iajs-3457	112	47	starting	start	VERB
iajs-3457	112	48	to	to	PART
iajs-3457	112	49	happen	happen	VERB
iajs-3457	112	50	.	.	PUNCT
iajs-3457	113	1	moreover	moreover	ADV
iajs-3457	113	2	,	,	PUNCT
iajs-3457	113	3	[	[	X
iajs-3457	113	4	37	37	NUM
iajs-3457	113	5	]	]	PUNCT
iajs-3457	113	6	discovered	discover	VERB
iajs-3457	113	7	that	that	SCONJ
iajs-3457	113	8	patients	patient	NOUN
iajs-3457	113	9	with	with	ADP
iajs-3457	113	10	β	β	X
iajs-3457	113	11	-	-	PUNCT
iajs-3457	113	12	thalassemia	thalassemia	NOUN
iajs-3457	113	13	intermedia	intermedia	PROPN
iajs-3457	113	14	had	have	VERB
iajs-3457	113	15	considerably	considerably	ADV
iajs-3457	113	16	higher	high	ADJ
iajs-3457	113	17	levels	level	NOUN
iajs-3457	113	18	of	of	ADP
iajs-3457	113	19	all	all	DET
iajs-3457	113	20	endothelial	endothelial	ADJ
iajs-3457	113	21	adhesion	adhesion	NOUN
iajs-3457	113	22	molecules	molecule	NOUN
iajs-3457	113	23	as	as	ADV
iajs-3457	113	24	well	well	ADV
iajs-3457	113	25	as	as	ADP
iajs-3457	113	26	crp	crp	PROPN
iajs-3457	113	27	,	,	PUNCT
iajs-3457	113	28	and	and	CCONJ
iajs-3457	113	29	that	that	DET
iajs-3457	113	30	therapy	therapy	NOUN
iajs-3457	113	31	had	have	VERB
iajs-3457	113	32	no	no	DET
iajs-3457	113	33	effect	effect	NOUN
iajs-3457	113	34	.	.	PUNCT
iajs-3457	114	1	recent	recent	ADJ
iajs-3457	114	2	studies	study	NOUN
iajs-3457	114	3	have	have	AUX
iajs-3457	114	4	consistently	consistently	ADV
iajs-3457	114	5	found	find	VERB
iajs-3457	114	6	higher	high	ADJ
iajs-3457	114	7	crp	crp	PROPN
iajs-3457	114	8	levels	level	NOUN
iajs-3457	114	9	in	in	ADP
iajs-3457	114	10	thalassemia	thalassemia	NOUN
iajs-3457	114	11	patients	patient	NOUN
iajs-3457	114	12	,	,	PUNCT
iajs-3457	114	13	particularly	particularly	ADV
iajs-3457	114	14	in	in	ADP
iajs-3457	114	15	splenectomized	splenectomized	ADJ
iajs-3457	114	16	patients	patient	NOUN
iajs-3457	114	17	,	,	PUNCT
iajs-3457	114	18	compared	compare	VERB
iajs-3457	114	19	to	to	ADP
iajs-3457	114	20	healthy	healthy	ADJ
iajs-3457	114	21	individuals	individual	NOUN
iajs-3457	114	22	.	.	PUNCT
iajs-3457	115	1	table	table	NOUN
iajs-3457	115	2	3	3	NUM
iajs-3457	115	3	summarizes	summarize	VERB
iajs-3457	115	4	the	the	DET
iajs-3457	115	5	results	result	NOUN
iajs-3457	115	6	of	of	ADP
iajs-3457	115	7	pro	pro	ADJ
iajs-3457	115	8	-	-	ADJ
iajs-3457	115	9	inflammatory	inflammatory	ADJ
iajs-3457	115	10	cytokine	cytokine	ADJ
iajs-3457	115	11	concentrations	concentration	NOUN
iajs-3457	115	12	in	in	ADP
iajs-3457	115	13	β	β	NOUN
iajs-3457	115	14	-	-	ADJ
iajs-3457	115	15	thalassemia	thalassemia	NOUN
iajs-3457	115	16	patients	patient	NOUN
iajs-3457	115	17	and	and	CCONJ
iajs-3457	115	18	controls	control	NOUN
iajs-3457	115	19	in	in	ADP
iajs-3457	115	20	the	the	DET
iajs-3457	115	21	current	current	ADJ
iajs-3457	115	22	study	study	NOUN
iajs-3457	115	23	.	.	PUNCT
iajs-3457	116	1	the	the	DET
iajs-3457	116	2	amount	amount	NOUN
iajs-3457	116	3	of	of	ADP
iajs-3457	116	4	il-1β	il-1β	PROPN
iajs-3457	116	5	was	be	AUX
iajs-3457	116	6	significantly	significantly	ADV
iajs-3457	116	7	higher	high	ADJ
iajs-3457	116	8	(	(	PUNCT
iajs-3457	116	9	p<0.01	p<0.01	PROPN
iajs-3457	116	10	)	)	PUNCT
iajs-3457	116	11	in	in	ADP
iajs-3457	116	12	people	people	NOUN
iajs-3457	116	13	with	with	ADP
iajs-3457	116	14	β	β	NOUN
iajs-3457	116	15	-	-	NOUN
iajs-3457	116	16	thalassemia	thalassemia	NOUN
iajs-3457	116	17	(	(	PUNCT
iajs-3457	116	18	284.19	284.19	NUM
iajs-3457	116	19	±4.29	±4.29	NOUN
iajs-3457	116	20	pg	pg	NOUN
iajs-3457	116	21	/	/	SYM
iajs-3457	116	22	ml	ml	VERB
iajs-3457	116	23	)	)	PUNCT
iajs-3457	116	24	compared	compare	VERB
iajs-3457	116	25	to	to	ADP
iajs-3457	116	26	the	the	DET
iajs-3457	116	27	healthy	healthy	ADJ
iajs-3457	116	28	control	control	NOUN
iajs-3457	116	29	group	group	NOUN
iajs-3457	116	30	(	(	PUNCT
iajs-3457	116	31	142.09	142.09	NUM
iajs-3457	116	32	±0.70	±0.70	PROPN
iajs-3457	116	33	pg	pg	PROPN
iajs-3457	116	34	/	/	SYM
iajs-3457	116	35	ml	ml	VERB
iajs-3457	116	36	)	)	PUNCT
iajs-3457	116	37	.	.	PUNCT
iajs-3457	117	1	also	also	ADV
iajs-3457	117	2	,	,	PUNCT
iajs-3457	117	3	the	the	DET
iajs-3457	117	4	il-6	il-6	NUM
iajs-3457	117	5	level	level	NOUN
iajs-3457	117	6	was	be	AUX
iajs-3457	117	7	significantly	significantly	ADV
iajs-3457	117	8	higher	high	ADJ
iajs-3457	117	9	(	(	PUNCT
iajs-3457	117	10	p<0.01	p<0.01	PROPN
iajs-3457	117	11	)	)	PUNCT
iajs-3457	117	12	in	in	ADP
iajs-3457	117	13	the	the	DET
iajs-3457	117	14	β	β	NOUN
iajs-3457	117	15	-	-	PUNCT
iajs-3457	117	16	thalassemia	thalassemia	NOUN
iajs-3457	117	17	patients	patient	NOUN
iajs-3457	117	18	compared	compare	VERB
iajs-3457	117	19	to	to	ADP
iajs-3457	117	20	the	the	DET
iajs-3457	117	21	healthy	healthy	ADJ
iajs-3457	117	22	group	group	NOUN
iajs-3457	117	23	(	(	PUNCT
iajs-3457	117	24	11.43	11.43	NUM
iajs-3457	117	25	±0.32	±0.32	VERB
iajs-3457	117	26	pg	pg	NOUN
iajs-3457	117	27	/	/	SYM
iajs-3457	117	28	ml	ml	NOUN
iajs-3457	117	29	)	)	PUNCT
iajs-3457	117	30	.	.	PUNCT
iajs-3457	118	1	it	it	PRON
iajs-3457	118	2	was	be	AUX
iajs-3457	118	3	27.92	27.92	NUM
iajs-3457	118	4	±0.97	±0.97	NOUN
iajs-3457	118	5	pg	pg	PROPN
iajs-3457	118	6	/	/	SYM
iajs-3457	118	7	ml	ml	X
iajs-3457	119	1	in	in	ADP
iajs-3457	119	2	the	the	DET
iajs-3457	119	3	patients	patient	NOUN
iajs-3457	119	4	.	.	PUNCT
iajs-3457	120	1	ihjpas	ihjpas	PROPN
iajs-3457	120	2	.	.	PUNCT
iajs-3457	121	1	2024	2024	NUM
iajs-3457	121	2	,	,	PUNCT
iajs-3457	121	3	37(4	37(4	NOUN
iajs-3457	121	4	)	)	PUNCT
iajs-3457	121	5	40	40	NUM
iajs-3457	121	6	table	table	NOUN
iajs-3457	121	7	3	3	NUM
iajs-3457	121	8	.	.	X
iajs-3457	121	9	level	level	NOUN
iajs-3457	121	10	of	of	ADP
iajs-3457	121	11	il1β	il1β	PROPN
iajs-3457	121	12	and	and	CCONJ
iajs-3457	121	13	il-6	il-6	NOUN
iajs-3457	121	14	in	in	ADP
iajs-3457	121	15	β	β	NOUN
iajs-3457	121	16	-	-	NOUN
iajs-3457	121	17	thalassemia	thalassemia	VERB
iajs-3457	121	18	major	major	ADJ
iajs-3457	121	19	patients	patient	NOUN
iajs-3457	121	20	and	and	CCONJ
iajs-3457	121	21	control	control	NOUN
iajs-3457	121	22	group	group	NOUN
iajs-3457	121	23	mean	mean	VERB
iajs-3457	121	24	±	±	PROPN
iajs-3457	121	25	se	se	PROPN
iajs-3457	122	1	il-1β	il-1β	PROPN
iajs-3457	122	2	(	(	PUNCT
iajs-3457	122	3	pg	pg	NOUN
iajs-3457	122	4	/	/	SYM
iajs-3457	122	5	ml	ml	NOUN
iajs-3457	122	6	)	)	PUNCT
iajs-3457	122	7	il-6	il-6	NOUN
iajs-3457	123	1	(	(	PUNCT
iajs-3457	123	2	pg	pg	NOUN
iajs-3457	123	3	/	/	SYM
iajs-3457	123	4	ml	ml	NOUN
iajs-3457	123	5	)	)	PUNCT
iajs-3457	123	6	patients	patient	NOUN
iajs-3457	123	7	284.19	284.19	NUM
iajs-3457	123	8	±4.29	±4.29	NOUN
iajs-3457	123	9	27.92	27.92	NUM
iajs-3457	123	10	±0.97	±0.97	NOUN
iajs-3457	123	11	control	control	NOUN
iajs-3457	123	12	142.09	142.09	NUM
iajs-3457	123	13	±0.70	±0.70	PROPN
iajs-3457	123	14	11.43	11.43	NUM
iajs-3457	123	15	±0.32	±0.32	VERB
iajs-3457	123	16	t	t	PROPN
iajs-3457	123	17	-	-	PUNCT
iajs-3457	123	18	test	test	NOUN
iajs-3457	123	19	1.987	1.987	NUM
iajs-3457	123	20	*	*	PUNCT
iajs-3457	123	21	*	*	PUNCT
iajs-3457	123	22	2.778	2.778	NUM
iajs-3457	123	23	*	*	PUNCT
iajs-3457	124	1	*	*	PUNCT
iajs-3457	125	1	p	p	X
iajs-3457	125	2	-	-	PUNCT
iajs-3457	125	3	value	value	NOUN
iajs-3457	125	4	0.0001	0.0001	NUM
iajs-3457	125	5	0.0001	0.0001	NUM
iajs-3457	125	6	*	*	PUNCT
iajs-3457	125	7	*	*	PUNCT
iajs-3457	125	8	(	(	PUNCT
iajs-3457	125	9	p≤0.01	p≤0.01	NOUN
iajs-3457	125	10	)	)	PUNCT
iajs-3457	125	11	.	.	PUNCT
iajs-3457	126	1	the	the	DET
iajs-3457	126	2	results	result	NOUN
iajs-3457	126	3	of	of	ADP
iajs-3457	126	4	il-1β	il-1β	PROPN
iajs-3457	126	5	in	in	ADP
iajs-3457	126	6	the	the	DET
iajs-3457	126	7	present	present	ADJ
iajs-3457	126	8	study	study	NOUN
iajs-3457	126	9	are	be	AUX
iajs-3457	126	10	supported	support	VERB
iajs-3457	126	11	by	by	ADP
iajs-3457	126	12	the	the	DET
iajs-3457	126	13	results	result	NOUN
iajs-3457	126	14	of	of	ADP
iajs-3457	126	15	the	the	DET
iajs-3457	126	16	study	study	NOUN
iajs-3457	126	17	done	do	VERB
iajs-3457	126	18	[	[	PUNCT
iajs-3457	126	19	38	38	NUM
iajs-3457	126	20	]	]	PUNCT
iajs-3457	126	21	,	,	PUNCT
iajs-3457	126	22	where	where	SCONJ
iajs-3457	126	23	it	it	PRON
iajs-3457	126	24	showed	show	VERB
iajs-3457	126	25	an	an	DET
iajs-3457	126	26	increase	increase	NOUN
iajs-3457	126	27	in	in	ADP
iajs-3457	126	28	the	the	DET
iajs-3457	126	29	level	level	NOUN
iajs-3457	126	30	of	of	ADP
iajs-3457	126	31	il-1β	il-1β	PROPN
iajs-3457	126	32	compared	compare	VERB
iajs-3457	126	33	with	with	ADP
iajs-3457	126	34	the	the	DET
iajs-3457	126	35	control	control	NOUN
iajs-3457	126	36	group	group	NOUN
iajs-3457	126	37	.	.	PUNCT
iajs-3457	127	1	on	on	ADP
iajs-3457	127	2	the	the	DET
iajs-3457	127	3	other	other	ADJ
iajs-3457	127	4	hand	hand	NOUN
iajs-3457	127	5	,	,	PUNCT
iajs-3457	127	6	it	it	PRON
iajs-3457	127	7	has	have	AUX
iajs-3457	127	8	been	be	AUX
iajs-3457	127	9	demonstrated	demonstrate	VERB
iajs-3457	127	10	that	that	SCONJ
iajs-3457	127	11	tnfand	tnfand	NOUN
iajs-3457	127	12	il-1β	il-1β	PROPN
iajs-3457	127	13	play	play	VERB
iajs-3457	127	14	a	a	DET
iajs-3457	127	15	major	major	ADJ
iajs-3457	127	16	role	role	NOUN
iajs-3457	127	17	in	in	ADP
iajs-3457	127	18	mediating	mediate	VERB
iajs-3457	127	19	endothelial	endothelial	ADJ
iajs-3457	127	20	cell	cell	NOUN
iajs-3457	127	21	activation	activation	NOUN
iajs-3457	127	22	.	.	PUNCT
iajs-3457	128	1	there	there	PRON
iajs-3457	128	2	are	be	VERB
iajs-3457	128	3	too	too	ADV
iajs-3457	128	4	many	many	ADJ
iajs-3457	128	5	tnf	tnf	PROPN
iajs-3457	128	6	-	-	PUNCT
iajs-3457	128	7	a	a	NOUN
iajs-3457	128	8	and	and	CCONJ
iajs-3457	128	9	il-1β	il-1β	PROPN
iajs-3457	128	10	in	in	ADP
iajs-3457	128	11	people	people	NOUN
iajs-3457	128	12	with	with	ADP
iajs-3457	128	13	β	β	NOUN
iajs-3457	128	14	-	-	NOUN
iajs-3457	128	15	thalassemia	thalassemia	NOUN
iajs-3457	128	16	/	/	SYM
iajs-3457	128	17	hbe	hbe	NOUN
iajs-3457	128	18	.	.	PUNCT
iajs-3457	129	1	this	this	PRON
iajs-3457	129	2	could	could	AUX
iajs-3457	129	3	be	be	AUX
iajs-3457	129	4	a	a	DET
iajs-3457	129	5	mononuclear	mononuclear	ADJ
iajs-3457	129	6	phagocyte	phagocyte	NOUN
iajs-3457	129	7	response	response	NOUN
iajs-3457	129	8	to	to	ADP
iajs-3457	129	9	the	the	DET
iajs-3457	129	10	sick	sick	ADJ
iajs-3457	129	11	red	red	ADJ
iajs-3457	129	12	blood	blood	NOUN
iajs-3457	129	13	cells	cell	NOUN
iajs-3457	129	14	.	.	PUNCT
iajs-3457	130	1	these	these	DET
iajs-3457	130	2	monokines	monokine	NOUN
iajs-3457	130	3	,	,	PUNCT
iajs-3457	130	4	th1	th1	PROPN
iajs-3457	130	5	and	and	CCONJ
iajs-3457	130	6	nk	nk	PROPN
iajs-3457	130	7	,	,	PUNCT
iajs-3457	130	8	are	be	AUX
iajs-3457	130	9	most	most	ADV
iajs-3457	130	10	likely	likely	ADJ
iajs-3457	130	11	to	to	PART
iajs-3457	130	12	serve	serve	VERB
iajs-3457	130	13	as	as	ADP
iajs-3457	130	14	cofactors	cofactor	NOUN
iajs-3457	130	15	for	for	ADP
iajs-3457	130	16	the	the	DET
iajs-3457	130	17	synthesis	synthesis	NOUN
iajs-3457	130	18	of	of	ADP
iajs-3457	130	19	interferon	interferon	ADJ
iajs-3457	130	20	gamma	gamma	NOUN
iajs-3457	130	21	(	(	PUNCT
iajs-3457	130	22	ifn	ifn	PROPN
iajs-3457	130	23	-	-	PUNCT
iajs-3457	130	24	g	g	NOUN
iajs-3457	130	25	)	)	PUNCT
iajs-3457	131	1	[	[	X
iajs-3457	131	2	39	39	NUM
iajs-3457	131	3	]	]	PUNCT
iajs-3457	131	4	.	.	PUNCT
iajs-3457	132	1	as	as	ADV
iajs-3457	132	2	well	well	ADV
iajs-3457	132	3	as	as	ADP
iajs-3457	132	4	the	the	DET
iajs-3457	132	5	huge	huge	ADJ
iajs-3457	132	6	rise	rise	NOUN
iajs-3457	132	7	in	in	ADP
iajs-3457	132	8	interleukin-1β	interleukin-1β	ADJ
iajs-3457	132	9	levels	level	NOUN
iajs-3457	132	10	in	in	ADP
iajs-3457	132	11	thalassemia	thalassemia	NOUN
iajs-3457	132	12	patients	patient	NOUN
iajs-3457	132	13	in	in	ADP
iajs-3457	132	14	these	these	DET
iajs-3457	132	15	results	result	NOUN
iajs-3457	132	16	is	be	AUX
iajs-3457	132	17	similar	similar	ADJ
iajs-3457	132	18	to	to	ADP
iajs-3457	132	19	what	what	PRON
iajs-3457	132	20	was	be	AUX
iajs-3457	132	21	seen	see	VERB
iajs-3457	132	22	in	in	ADP
iajs-3457	132	23	the	the	DET
iajs-3457	132	24	study	study	NOUN
iajs-3457	132	25	[	[	X
iajs-3457	132	26	40	40	NUM
iajs-3457	132	27	]	]	PUNCT
iajs-3457	132	28	.	.	PUNCT
iajs-3457	133	1	compared	compare	VERB
iajs-3457	133	2	to	to	ADP
iajs-3457	133	3	the	the	DET
iajs-3457	133	4	control	control	NOUN
iajs-3457	133	5	group	group	NOUN
iajs-3457	133	6	,	,	PUNCT
iajs-3457	133	7	the	the	DET
iajs-3457	133	8	thalassemia	thalassemia	NOUN
iajs-3457	133	9	patients	patient	NOUN
iajs-3457	133	10	in	in	ADP
iajs-3457	133	11	this	this	DET
iajs-3457	133	12	study	study	NOUN
iajs-3457	133	13	had	have	VERB
iajs-3457	133	14	a	a	DET
iajs-3457	133	15	much	much	ADV
iajs-3457	133	16	higher	high	ADJ
iajs-3457	133	17	level	level	NOUN
iajs-3457	133	18	of	of	ADP
iajs-3457	133	19	il-1β	il-1β	PROPN
iajs-3457	133	20	than	than	ADP
iajs-3457	133	21	the	the	DET
iajs-3457	133	22	healthy	healthy	ADJ
iajs-3457	133	23	people	people	NOUN
iajs-3457	133	24	in	in	ADP
iajs-3457	133	25	the	the	DET
iajs-3457	133	26	control	control	NOUN
iajs-3457	133	27	group	group	NOUN
iajs-3457	133	28	.	.	PUNCT
iajs-3457	134	1	numerous	numerous	ADJ
iajs-3457	134	2	significant	significant	ADJ
iajs-3457	134	3	cytokines	cytokine	NOUN
iajs-3457	134	4	,	,	PUNCT
iajs-3457	134	5	such	such	ADJ
iajs-3457	134	6	as	as	ADP
iajs-3457	134	7	interleukin-1	interleukin-1	NUM
iajs-3457	134	8	beta	beta	NOUN
iajs-3457	134	9	(	(	PUNCT
iajs-3457	134	10	il-1	il-1	NUM
iajs-3457	134	11	)	)	PUNCT
iajs-3457	134	12	,	,	PUNCT
iajs-3457	134	13	are	be	AUX
iajs-3457	134	14	believed	believe	VERB
iajs-3457	134	15	to	to	PART
iajs-3457	134	16	be	be	AUX
iajs-3457	134	17	major	major	ADJ
iajs-3457	134	18	inflammatory	inflammatory	ADJ
iajs-3457	134	19	mediators	mediator	NOUN
iajs-3457	134	20	that	that	PRON
iajs-3457	134	21	damage	damage	VERB
iajs-3457	134	22	diverse	diverse	ADJ
iajs-3457	134	23	organs	organ	NOUN
iajs-3457	134	24	.	.	PUNCT
iajs-3457	135	1	furthermore	furthermore	ADV
iajs-3457	135	2	,	,	PUNCT
iajs-3457	135	3	the	the	DET
iajs-3457	135	4	highly	highly	ADV
iajs-3457	135	5	significant	significant	ADJ
iajs-3457	135	6	(	(	PUNCT
iajs-3457	135	7	p<0.01	p<0.01	PROPN
iajs-3457	135	8	)	)	PUNCT
iajs-3457	135	9	increase	increase	NOUN
iajs-3457	135	10	in	in	ADP
iajs-3457	135	11	the	the	DET
iajs-3457	135	12	level	level	NOUN
iajs-3457	135	13	of	of	ADP
iajs-3457	135	14	il-6	il-6	NOUN
iajs-3457	135	15	in	in	ADP
iajs-3457	135	16	the	the	DET
iajs-3457	135	17	β	β	NOUN
iajs-3457	135	18	-	-	PUNCT
iajs-3457	135	19	thalassemia	thalassemia	NOUN
iajs-3457	135	20	patients	patient	NOUN
iajs-3457	135	21	in	in	ADP
iajs-3457	135	22	the	the	DET
iajs-3457	135	23	current	current	ADJ
iajs-3457	135	24	study	study	NOUN
iajs-3457	135	25	agrees	agree	VERB
iajs-3457	135	26	with	with	ADP
iajs-3457	135	27	the	the	DET
iajs-3457	135	28	study	study	NOUN
iajs-3457	135	29	[	[	X
iajs-3457	135	30	41	41	NUM
iajs-3457	135	31	]	]	PUNCT
iajs-3457	135	32	.	.	PUNCT
iajs-3457	136	1	the	the	DET
iajs-3457	136	2	study	study	NOUN
iajs-3457	136	3	has	have	AUX
iajs-3457	136	4	concentrated	concentrate	VERB
iajs-3457	136	5	on	on	ADP
iajs-3457	136	6	the	the	DET
iajs-3457	136	7	connection	connection	NOUN
iajs-3457	136	8	between	between	ADP
iajs-3457	136	9	il-6	il-6	NOUN
iajs-3457	136	10	and	and	CCONJ
iajs-3457	136	11	adiponectin	adiponectin	NOUN
iajs-3457	136	12	,	,	PUNCT
iajs-3457	136	13	positing	posit	VERB
iajs-3457	136	14	that	that	SCONJ
iajs-3457	136	15	adiponectin	adiponectin	NOUN
iajs-3457	136	16	serves	serve	VERB
iajs-3457	136	17	as	as	ADP
iajs-3457	136	18	a	a	DET
iajs-3457	136	19	potent	potent	ADJ
iajs-3457	136	20	trigger	trigger	NOUN
iajs-3457	136	21	for	for	ADP
iajs-3457	136	22	il-6	il-6	PRON
iajs-3457	136	23	and	and	CCONJ
iajs-3457	136	24	tnfsecretion	tnfsecretion	NOUN
iajs-3457	136	25	in	in	ADP
iajs-3457	136	26	primary	primary	ADJ
iajs-3457	136	27	human	human	ADJ
iajs-3457	136	28	peripheral	peripheral	ADJ
iajs-3457	136	29	macrophages	macrophage	NOUN
iajs-3457	136	30	.	.	PUNCT
iajs-3457	137	1	moreover	moreover	ADV
iajs-3457	137	2	,	,	PUNCT
iajs-3457	137	3	the	the	DET
iajs-3457	137	4	cytokine	cytokine	NOUN
iajs-3457	137	5	interleukin-6	interleukin-6	NUM
iajs-3457	137	6	(	(	PUNCT
iajs-3457	137	7	il-6	il-6	NUM
iajs-3457	137	8	)	)	PUNCT
iajs-3457	137	9	triggers	trigger	VERB
iajs-3457	137	10	the	the	DET
iajs-3457	137	11	transformation	transformation	NOUN
iajs-3457	137	12	of	of	ADP
iajs-3457	137	13	t	t	PROPN
iajs-3457	137	14	helper	helper	NOUN
iajs-3457	137	15	cells	cell	NOUN
iajs-3457	137	16	into	into	ADP
iajs-3457	137	17	th17	th17	NOUN
iajs-3457	137	18	cells	cell	NOUN
iajs-3457	137	19	,	,	PUNCT
iajs-3457	137	20	a	a	DET
iajs-3457	137	21	combination	combination	NOUN
iajs-3457	137	22	of	of	ADP
iajs-3457	137	23	macrophages	macrophage	NOUN
iajs-3457	137	24	and	and	CCONJ
iajs-3457	137	25	t	t	NOUN
iajs-3457	137	26	lymphocytes	lymphocyte	VERB
iajs-3457	137	27	that	that	SCONJ
iajs-3457	137	28	significantly	significantly	ADV
iajs-3457	137	29	contribute	contribute	VERB
iajs-3457	137	30	to	to	ADP
iajs-3457	137	31	the	the	DET
iajs-3457	137	32	immune	immune	ADJ
iajs-3457	137	33	response	response	NOUN
iajs-3457	137	34	.	.	PUNCT
iajs-3457	138	1	it	it	PRON
iajs-3457	138	2	also	also	ADV
iajs-3457	138	3	plays	play	VERB
iajs-3457	138	4	a	a	DET
iajs-3457	138	5	role	role	NOUN
iajs-3457	138	6	in	in	ADP
iajs-3457	138	7	both	both	CCONJ
iajs-3457	138	8	local	local	ADJ
iajs-3457	138	9	tissue	tissue	NOUN
iajs-3457	138	10	inflammation	inflammation	NOUN
iajs-3457	138	11	and	and	CCONJ
iajs-3457	138	12	the	the	DET
iajs-3457	138	13	systemic	systemic	ADJ
iajs-3457	138	14	inflammatory	inflammatory	ADJ
iajs-3457	138	15	response	response	NOUN
iajs-3457	138	16	[	[	X
iajs-3457	138	17	42	42	NUM
iajs-3457	138	18	]	]	PUNCT
iajs-3457	138	19	.	.	PUNCT
iajs-3457	139	1	also	also	ADV
iajs-3457	139	2	,	,	PUNCT
iajs-3457	139	3	as	as	SCONJ
iajs-3457	139	4	found	find	VERB
iajs-3457	139	5	in	in	ADP
iajs-3457	139	6	other	other	ADJ
iajs-3457	139	7	studies	study	NOUN
iajs-3457	139	8	,	,	PUNCT
iajs-3457	139	9	serum	serum	NOUN
iajs-3457	139	10	levels	level	NOUN
iajs-3457	139	11	of	of	ADP
iajs-3457	139	12	il-6	il-6	NUM
iajs-3457	139	13	were	be	AUX
iajs-3457	139	14	significantly	significantly	ADV
iajs-3457	139	15	higher	high	ADJ
iajs-3457	139	16	in	in	ADP
iajs-3457	139	17	patients	patient	NOUN
iajs-3457	139	18	with	with	ADP
iajs-3457	139	19	betathalassemia	betathalassemia	NOUN
iajs-3457	139	20	compared	compare	VERB
iajs-3457	139	21	to	to	ADP
iajs-3457	139	22	the	the	DET
iajs-3457	139	23	control	control	NOUN
iajs-3457	139	24	group	group	NOUN
iajs-3457	140	1	[	[	X
iajs-3457	140	2	43	43	NUM
iajs-3457	140	3	]	]	PUNCT
iajs-3457	140	4	.	.	PUNCT
iajs-3457	141	1	4.conclusion	4.conclusion	NUM
iajs-3457	141	2	beta	beta	NOUN
iajs-3457	141	3	-	-	PUNCT
iajs-3457	141	4	ttalassemia	ttalassemia	NOUN
iajs-3457	141	5	major	major	NOUN
iajs-3457	141	6	is	be	AUX
iajs-3457	141	7	a	a	DET
iajs-3457	141	8	genetic	genetic	ADJ
iajs-3457	141	9	disease	disease	NOUN
iajs-3457	141	10	that	that	PRON
iajs-3457	141	11	affects	affect	VERB
iajs-3457	141	12	the	the	DET
iajs-3457	141	13	production	production	NOUN
iajs-3457	141	14	of	of	ADP
iajs-3457	141	15	hemoglobin	hemoglobin	NOUN
iajs-3457	141	16	.	.	PUNCT
iajs-3457	142	1	it	it	PRON
iajs-3457	142	2	causes	cause	VERB
iajs-3457	142	3	severe	severe	ADJ
iajs-3457	142	4	anemia	anemia	NOUN
iajs-3457	142	5	in	in	ADP
iajs-3457	142	6	countries	country	NOUN
iajs-3457	142	7	in	in	ADP
iajs-3457	142	8	the	the	DET
iajs-3457	142	9	middle	middle	PROPN
iajs-3457	142	10	east	east	PROPN
iajs-3457	142	11	and	and	CCONJ
iajs-3457	142	12	the	the	DET
iajs-3457	142	13	mediterranean	mediterranean	PROPN
iajs-3457	142	14	.	.	PUNCT
iajs-3457	143	1	patients	patient	NOUN
iajs-3457	143	2	who	who	PRON
iajs-3457	143	3	get	get	VERB
iajs-3457	143	4	multiple	multiple	ADJ
iajs-3457	143	5	blood	blood	NOUN
iajs-3457	143	6	transfusions	transfusion	NOUN
iajs-3457	143	7	end	end	VERB
iajs-3457	143	8	up	up	ADP
iajs-3457	143	9	with	with	ADP
iajs-3457	143	10	iron	iron	NOUN
iajs-3457	143	11	overload	overload	NOUN
iajs-3457	143	12	,	,	PUNCT
iajs-3457	143	13	which	which	PRON
iajs-3457	143	14	causes	cause	VERB
iajs-3457	143	15	oxidative	oxidative	ADJ
iajs-3457	143	16	stress	stress	NOUN
iajs-3457	143	17	and	and	CCONJ
iajs-3457	143	18	weakens	weaken	VERB
iajs-3457	143	19	their	their	PRON
iajs-3457	143	20	immune	immune	ADJ
iajs-3457	143	21	systems	system	NOUN
iajs-3457	143	22	.	.	PUNCT
iajs-3457	144	1	the	the	DET
iajs-3457	144	2	pro	pro	ADJ
iajs-3457	144	3	-	-	ADJ
iajs-3457	144	4	inflammatory	inflammatory	ADJ
iajs-3457	144	5	cytokines	cytokine	NOUN
iajs-3457	144	6	,	,	PUNCT
iajs-3457	144	7	especially	especially	ADV
iajs-3457	144	8	interleukin-6	interleukin-6	NUM
iajs-3457	144	9	,	,	PUNCT
iajs-3457	144	10	are	be	AUX
iajs-3457	144	11	responsible	responsible	ADJ
iajs-3457	144	12	for	for	ADP
iajs-3457	144	13	local	local	ADJ
iajs-3457	144	14	inflammation	inflammation	NOUN
iajs-3457	144	15	and	and	CCONJ
iajs-3457	144	16	play	play	VERB
iajs-3457	144	17	a	a	DET
iajs-3457	144	18	significant	significant	ADJ
iajs-3457	144	19	role	role	NOUN
iajs-3457	144	20	in	in	ADP
iajs-3457	144	21	the	the	DET
iajs-3457	144	22	progression	progression	NOUN
iajs-3457	144	23	of	of	ADP
iajs-3457	144	24	the	the	DET
iajs-3457	144	25	disease	disease	NOUN
iajs-3457	144	26	.	.	PUNCT
iajs-3457	145	1	also	also	ADV
iajs-3457	145	2	,	,	PUNCT
iajs-3457	145	3	il-1β	il-1β	PROPN
iajs-3457	145	4	plays	play	VERB
iajs-3457	145	5	a	a	DET
iajs-3457	145	6	major	major	ADJ
iajs-3457	145	7	role	role	NOUN
iajs-3457	145	8	in	in	ADP
iajs-3457	145	9	mediating	mediate	VERB
iajs-3457	145	10	endothelial	endothelial	ADJ
iajs-3457	145	11	cell	cell	NOUN
iajs-3457	145	12	activation	activation	NOUN
iajs-3457	145	13	and	and	CCONJ
iajs-3457	145	14	is	be	AUX
iajs-3457	145	15	thought	think	VERB
iajs-3457	145	16	to	to	PART
iajs-3457	145	17	be	be	AUX
iajs-3457	145	18	a	a	DET
iajs-3457	145	19	major	major	ADJ
iajs-3457	145	20	inflammatory	inflammatory	ADJ
iajs-3457	145	21	mediator	mediator	NOUN
iajs-3457	145	22	that	that	PRON
iajs-3457	145	23	damages	damage	VERB
iajs-3457	145	24	diverse	diverse	ADJ
iajs-3457	145	25	organs	organ	NOUN
iajs-3457	145	26	.	.	PUNCT
iajs-3457	146	1	acknowledgment	acknowledgment	NOUN
iajs-3457	146	2	many	many	ADJ
iajs-3457	146	3	thanks	thank	NOUN
iajs-3457	146	4	to	to	ADP
iajs-3457	146	5	editor	editor	NOUN
iajs-3457	146	6	-	-	PUNCT
iajs-3457	146	7	in	in	ADP
iajs-3457	146	8	-	-	PUNCT
iajs-3457	146	9	chief	chief	NOUN
iajs-3457	146	10	and	and	CCONJ
iajs-3457	146	11	members	member	NOUN
iajs-3457	146	12	of	of	ADP
iajs-3457	146	13	the	the	DET
iajs-3457	146	14	editorial	editorial	ADJ
iajs-3457	146	15	committee	committee	NOUN
iajs-3457	146	16	in	in	ADP
iajs-3457	146	17	ibn	ibn	PROPN
iajs-3457	146	18	alhaitham	alhaitham	NOUN
iajs-3457	146	19	journal	journal	NOUN
iajs-3457	146	20	for	for	ADP
iajs-3457	146	21	pure	pure	ADJ
iajs-3457	146	22	and	and	CCONJ
iajs-3457	146	23	applied	applied	ADJ
iajs-3457	146	24	sciences	science	NOUN
iajs-3457	146	25	.	.	PUNCT
iajs-3457	147	1	ihjpas	ihjpas	PROPN
iajs-3457	147	2	.	.	PUNCT
iajs-3457	148	1	2024	2024	NUM
iajs-3457	148	2	,	,	PUNCT
iajs-3457	148	3	37(4	37(4	NOUN
iajs-3457	148	4	)	)	PUNCT
iajs-3457	148	5	41	41	NUM
iajs-3457	148	6	conflict	conflict	NOUN
iajs-3457	148	7	of	of	ADP
iajs-3457	148	8	interest	interest	NOUN
iajs-3457	148	9	there	there	PRON
iajs-3457	148	10	is	be	VERB
iajs-3457	148	11	no	no	DET
iajs-3457	148	12	conflict	conflict	NOUN
iajs-3457	148	13	of	of	ADP
iajs-3457	148	14	interest	interest	NOUN
iajs-3457	148	15	.	.	PUNCT
iajs-3457	149	1	funding	funding	NOUN
iajs-3457	149	2	there	there	PRON
iajs-3457	149	3	is	be	VERB
iajs-3457	149	4	no	no	DET
iajs-3457	149	5	funding	funding	NOUN
iajs-3457	149	6	for	for	ADP
iajs-3457	149	7	the	the	DET
iajs-3457	149	8	article	article	NOUN
iajs-3457	149	9	.	.	PUNCT
iajs-3457	150	1	ethical	ethical	ADJ
iajs-3457	150	2	clearance	clearance	NOUN
iajs-3457	150	3	ethics	ethic	NOUN
iajs-3457	150	4	of	of	ADP
iajs-3457	150	5	scientific	scientific	ADJ
iajs-3457	150	6	research	research	NOUN
iajs-3457	150	7	were	be	AUX
iajs-3457	150	8	carried	carry	VERB
iajs-3457	150	9	out	out	ADP
iajs-3457	150	10	in	in	ADP
iajs-3457	150	11	accordance	accordance	NOUN
iajs-3457	150	12	with	with	ADP
iajs-3457	150	13	the	the	DET
iajs-3457	150	14	international	international	ADJ
iajs-3457	150	15	conditions	condition	NOUN
iajs-3457	150	16	followed	follow	VERB
iajs-3457	150	17	in	in	ADP
iajs-3457	150	18	dealing	deal	VERB
iajs-3457	150	19	with	with	ADP
iajs-3457	150	20	laboratory	laboratory	NOUN
iajs-3457	150	21	animals	animal	NOUN
iajs-3457	150	22	,	,	PUNCT
iajs-3457	150	23	and	and	CCONJ
iajs-3457	150	24	included	include	VERB
iajs-3457	150	25	animal	animal	NOUN
iajs-3457	150	26	health	health	NOUN
iajs-3457	150	27	,	,	PUNCT
iajs-3457	150	28	husbandry	husbandry	NOUN
iajs-3457	150	29	and	and	CCONJ
iajs-3457	150	30	care	care	VERB
iajs-3457	150	31	for	for	ADP
iajs-3457	150	32	it	it	PRON
iajs-3457	150	33	,	,	PUNCT
iajs-3457	150	34	and	and	CCONJ
iajs-3457	150	35	providing	provide	VERB
iajs-3457	150	36	appropriate	appropriate	ADJ
iajs-3457	150	37	conditions	condition	NOUN
iajs-3457	150	38	for	for	ADP
iajs-3457	150	39	it	it	PRON
iajs-3457	150	40	in	in	ADP
iajs-3457	150	41	terms	term	NOUN
iajs-3457	150	42	of	of	ADP
iajs-3457	150	43	food	food	NOUN
iajs-3457	150	44	,	,	PUNCT
iajs-3457	150	45	and	and	CCONJ
iajs-3457	150	46	appropriate	appropriate	ADJ
iajs-3457	150	47	methods	method	NOUN
iajs-3457	150	48	were	be	AUX
iajs-3457	150	49	adopted	adopt	VERB
iajs-3457	150	50	in	in	ADP
iajs-3457	150	51	dealing	deal	VERB
iajs-3457	150	52	with	with	ADP
iajs-3457	150	53	it	it	PRON
iajs-3457	150	54	when	when	SCONJ
iajs-3457	150	55	experimenting	experiment	VERB
iajs-3457	150	56	,	,	PUNCT
iajs-3457	150	57	and	and	CCONJ
iajs-3457	150	58	this	this	PRON
iajs-3457	150	59	is	be	AUX
iajs-3457	150	60	consistent	consistent	ADJ
iajs-3457	150	61	with	with	ADP
iajs-3457	150	62	the	the	DET
iajs-3457	150	63	instructions	instruction	NOUN
iajs-3457	150	64	of	of	ADP
iajs-3457	150	65	the	the	DET
iajs-3457	150	66	iraqi	iraqi	ADJ
iajs-3457	150	67	ministry	ministry	PROPN
iajs-3457	150	68	of	of	ADP
iajs-3457	150	69	health	health	PROPN
iajs-3457	150	70	and	and	CCONJ
iajs-3457	150	71	environment	environment	NOUN
iajs-3457	150	72	were	be	AUX
iajs-3457	150	73	enrolled	enrol	VERB
iajs-3457	150	74	in	in	ADP
iajs-3457	150	75	this	this	DET
iajs-3457	150	76	study	study	NOUN
iajs-3457	150	77	during	during	ADP
iajs-3457	150	78	their	their	PRON
iajs-3457	150	79	attendance	attendance	NOUN
iajs-3457	150	80	at	at	ADP
iajs-3457	150	81	"	"	PUNCT
iajs-3457	150	82	abin	abin	PROPN
iajs-3457	150	83	al	al	PROPN
iajs-3457	150	84	-	-	PUNCT
iajs-3457	150	85	baladi	baladi	PROPN
iajs-3457	150	86	hospital	hospital	NOUN
iajs-3457	150	87	in	in	ADP
iajs-3457	150	88	baghdad	baghdad	PROPN
iajs-3457	150	89	"	"	PUNCT
iajs-3457	150	90	from	from	ADP
iajs-3457	150	91	september	september	PROPN
iajs-3457	150	92	2022	2022	NUM
iajs-3457	150	93	to	to	ADP
iajs-3457	150	94	january	january	PROPN
iajs-3457	150	95	2023	2023	NUM
iajs-3457	150	96	,	,	PUNCT
iajs-3457	150	97	college	college	NOUN
iajs-3457	150	98	of	of	ADP
iajs-3457	150	99	science	science	NOUN
iajs-3457	150	100	csec/0922/0104	csec/0922/0104	NOUN
iajs-3457	150	101	in	in	ADP
iajs-3457	150	102	2022/9/28	2022/9/28	NUM
iajs-3457	150	103	.	.	PUNCT
iajs-3457	151	1	references	reference	NOUN
iajs-3457	151	2	1	1	NUM
iajs-3457	151	3	.	.	PUNCT
iajs-3457	151	4	gaudio	gaudio	PROPN
iajs-3457	151	5	,	,	PUNCT
iajs-3457	151	6	a.	a.	NOUN
iajs-3457	151	7	;	;	PUNCT
iajs-3457	151	8	morabito	morabito	ADJ
iajs-3457	151	9	,	,	PUNCT
iajs-3457	151	10	n.	n.	PROPN
iajs-3457	151	11	;	;	PUNCT
iajs-3457	151	12	catalano	catalano	PROPN
iajs-3457	151	13	,	,	PUNCT
iajs-3457	151	14	a.	a.	PROPN
iajs-3457	151	15	;	;	PUNCT
iajs-3457	151	16	rapisarda	rapisarda	PROPN
iajs-3457	151	17	,	,	PUNCT
iajs-3457	151	18	r.	r.	PROPN
iajs-3457	151	19	;	;	PUNCT
iajs-3457	151	20	xourafa	xourafa	PROPN
iajs-3457	151	21	,	,	PUNCT
iajs-3457	151	22	a.	a.	PROPN
iajs-3457	151	23	;	;	PUNCT
iajs-3457	151	24	lasco	lasco	PROPN
iajs-3457	151	25	,	,	PUNCT
iajs-3457	151	26	a.	a.	NOUN
iajs-3457	151	27	pathogenesis	pathogenesis	NOUN
iajs-3457	151	28	of	of	ADP
iajs-3457	151	29	thalassemia	thalassemia	PROPN
iajs-3457	151	30	major	major	ADJ
iajs-3457	151	31	-	-	PUNCT
iajs-3457	151	32	associated	associate	VERB
iajs-3457	151	33	osteoporosis	osteoporosis	NOUN
iajs-3457	151	34	:	:	PUNCT
iajs-3457	151	35	a	a	DET
iajs-3457	151	36	review	review	NOUN
iajs-3457	151	37	with	with	ADP
iajs-3457	151	38	insights	insight	NOUN
iajs-3457	151	39	from	from	ADP
iajs-3457	151	40	clinical	clinical	ADJ
iajs-3457	151	41	experience	experience	NOUN
iajs-3457	151	42	.	.	PUNCT
iajs-3457	152	1	journal	journal	NOUN
iajs-3457	152	2	of	of	ADP
iajs-3457	152	3	clinical	clinical	ADJ
iajs-3457	152	4	research	research	NOUN
iajs-3457	152	5	in	in	ADP
iajs-3457	152	6	pediatric	pediatric	ADJ
iajs-3457	152	7	endocrinology	endocrinology	NOUN
iajs-3457	152	8	2019	2019	NUM
iajs-3457	152	9	,	,	PUNCT
iajs-3457	152	10	11(2	11(2	NUM
iajs-3457	152	11	)	)	PUNCT
iajs-3457	152	12	,	,	PUNCT
iajs-3457	152	13	110	110	NUM
iajs-3457	152	14	-	-	SYM
iajs-3457	152	15	117	117	NUM
iajs-3457	152	16	.	.	PUNCT
iajs-3457	153	1	https://doi.org/10.4274/jcrpe.galenos.2018.2018.0074	https://doi.org/10.4274/jcrpe.galenos.2018.2018.0074	PROPN
iajs-3457	153	2	.	.	PUNCT
iajs-3457	154	1	2	2	X
iajs-3457	154	2	.	.	X
iajs-3457	154	3	bajwa	bajwa	PROPN
iajs-3457	154	4	,	,	PUNCT
iajs-3457	154	5	h.	h.	PROPN
iajs-3457	154	6	basit	basit	PROPN
iajs-3457	154	7	,	,	PUNCT
iajs-3457	154	8	h.	h.	PROPN
iajs-3457	154	9	thalassemia	thalassemia	PROPN
iajs-3457	154	10	,	,	PUNCT
iajs-3457	154	11	1st	1st	ADJ
iajs-3457	154	12	edition	edition	NOUN
iajs-3457	154	13	2019	2019	NUM
iajs-3457	154	14	.	.	PUNCT
iajs-3457	155	1	stat	stat	PROPN
iajs-3457	155	2	pearls	pearl	NOUN
iajs-3457	155	3	publishing	publishing	NOUN
iajs-3457	155	4	:	:	PUNCT
iajs-3457	155	5	treasure	treasure	NOUN
iajs-3457	155	6	island	island	NOUN
iajs-3457	155	7	,	,	PUNCT
iajs-3457	155	8	fl	fl	PROPN
iajs-3457	155	9	,	,	PUNCT
iajs-3457	155	10	usa	usa	PROPN
iajs-3457	155	11	.	.	PROPN
iajs-3457	155	12	https://doi.org/10.7759/cureus.32491	https://doi.org/10.7759/cureus.32491	NOUN
iajs-3457	155	13	.	.	PUNCT
iajs-3457	156	1	3	3	X
iajs-3457	156	2	.	.	X
iajs-3457	156	3	fraidenburg	fraidenburg	PROPN
iajs-3457	156	4	,	,	PUNCT
iajs-3457	156	5	d.r	d.r	PROPN
iajs-3457	156	6	.	.	PROPN
iajs-3457	156	7	;	;	PUNCT
iajs-3457	157	1	machado	machado	PROPN
iajs-3457	157	2	,	,	PUNCT
iajs-3457	157	3	r.f	r.f	PROPN
iajs-3457	157	4	.	.	PROPN
iajs-3457	157	5	pulmonary	pulmonary	ADJ
iajs-3457	157	6	hypertension	hypertension	NOUN
iajs-3457	157	7	associated	associate	VERB
iajs-3457	157	8	with	with	ADP
iajs-3457	157	9	thalassemia	thalassemia	NOUN
iajs-3457	157	10	syndromes	syndrome	NOUN
iajs-3457	157	11	.	.	PUNCT
iajs-3457	158	1	annals	annal	NOUN
iajs-3457	158	2	of	of	ADP
iajs-3457	158	3	the	the	DET
iajs-3457	158	4	new	new	PROPN
iajs-3457	158	5	york	york	PROPN
iajs-3457	158	6	academy	academy	PROPN
iajs-3457	158	7	of	of	ADP
iajs-3457	158	8	sciences	sciences	PROPN
iajs-3457	158	9	2016	2016	NUM
iajs-3457	158	10	,	,	PUNCT
iajs-3457	158	11	1368	1368	NUM
iajs-3457	158	12	(	(	PUNCT
iajs-3457	158	13	1	1	NUM
iajs-3457	158	14	)	)	PUNCT
iajs-3457	158	15	,	,	PUNCT
iajs-3457	158	16	127	127	NUM
iajs-3457	158	17	-	-	SYM
iajs-3457	158	18	139	139	NUM
iajs-3457	158	19	.	.	PUNCT
iajs-3457	159	1	https://doi.org/10.1111/nyas.13037	https://doi.org/10.1111/nyas.13037	NOUN
iajs-3457	159	2	.	.	PUNCT
iajs-3457	160	1	4	4	X
iajs-3457	160	2	.	.	X
iajs-3457	160	3	yenzeel	yenzeel	PROPN
iajs-3457	160	4	,	,	PUNCT
iajs-3457	160	5	j.h	j.h	PROPN
iajs-3457	160	6	.	.	PUNCT
iajs-3457	161	1	the	the	DET
iajs-3457	161	2	variation	variation	NOUN
iajs-3457	161	3	in	in	ADP
iajs-3457	161	4	levels	level	NOUN
iajs-3457	161	5	of	of	ADP
iajs-3457	161	6	some	some	DET
iajs-3457	161	7	male	male	ADJ
iajs-3457	161	8	pituitary	pituitary	ADJ
iajs-3457	161	9	and	and	CCONJ
iajs-3457	161	10	gonadal	gonadal	ADJ
iajs-3457	161	11	hormones	hormone	NOUN
iajs-3457	161	12	in	in	ADP
iajs-3457	161	13	betathalassemia	betathalassemia	NOUN
iajs-3457	161	14	major	major	ADJ
iajs-3457	161	15	patients	patient	NOUN
iajs-3457	161	16	in	in	ADP
iajs-3457	161	17	iraq	iraq	PROPN
iajs-3457	161	18	.	.	PUNCT
iajs-3457	162	1	iraqi	iraqi	ADJ
iajs-3457	162	2	journal	journal	PROPN
iajs-3457	162	3	of	of	ADP
iajs-3457	162	4	science	science	NOUN
iajs-3457	162	5	2017	2017	NUM
iajs-3457	162	6	,	,	PUNCT
iajs-3457	162	7	58(1b	58(1b	NUM
iajs-3457	162	8	)	)	PUNCT
iajs-3457	162	9	,	,	PUNCT
iajs-3457	162	10	216	216	NUM
iajs-3457	162	11	-	-	SYM
iajs-3457	162	12	221	221	NUM
iajs-3457	162	13	.	.	PUNCT
iajs-3457	163	1	5	5	NUM
iajs-3457	163	2	.	.	PUNCT
iajs-3457	163	3	ahmed	ahmed	PROPN
iajs-3457	163	4	,	,	PUNCT
iajs-3457	163	5	a.k	a.k	PROPN
iajs-3457	163	6	.	.	PROPN
iajs-3457	163	7	;	;	PUNCT
iajs-3457	163	8	yenzeel	yenzeel	PROPN
iajs-3457	163	9	,	,	PUNCT
iajs-3457	163	10	j.	j.	PROPN
iajs-3457	163	11	h.	h.	PROPN
iajs-3457	163	12	determination	determination	NOUN
iajs-3457	163	13	of	of	ADP
iajs-3457	163	14	some	some	DET
iajs-3457	163	15	oxidative	oxidative	ADJ
iajs-3457	163	16	stress	stress	NOUN
iajs-3457	163	17	parameters	parameter	NOUN
iajs-3457	163	18	and	and	CCONJ
iajs-3457	163	19	antioxidants	antioxidant	NOUN
iajs-3457	163	20	in	in	ADP
iajs-3457	163	21	sample	sample	NOUN
iajs-3457	163	22	of	of	ADP
iajs-3457	163	23	iraqi	iraqi	ADJ
iajs-3457	163	24	beta	beta	NOUN
iajs-3457	163	25	thalassemia	thalassemia	NOUN
iajs-3457	163	26	major	major	ADJ
iajs-3457	163	27	patients	patient	NOUN
iajs-3457	163	28	.	.	PUNCT
iajs-3457	164	1	iraqi	iraqi	ADJ
iajs-3457	164	2	journal	journal	PROPN
iajs-3457	164	3	of	of	ADP
iajs-3457	164	4	science	science	PROPN
iajs-3457	164	5	2017	2017	NUM
iajs-3457	164	6	,	,	PUNCT
iajs-3457	164	7	58(1a	58(1a	NUM
iajs-3457	164	8	)	)	PUNCT
iajs-3457	164	9	,	,	PUNCT
iajs-3457	164	10	1	1	NUM
iajs-3457	164	11	-	-	SYM
iajs-3457	164	12	3	3	NUM
iajs-3457	164	13	.	.	PUNCT
iajs-3457	164	14	https://ijs.uobaghdad.edu.iq/index.php/eijs/article/view/6182	https://ijs.uobaghdad.edu.iq/index.php/eijs/article/view/6182	PROPN
iajs-3457	164	15	.	.	PUNCT
iajs-3457	165	1	6	6	NUM
iajs-3457	165	2	.	.	X
iajs-3457	166	1	origa	origa	PROPN
iajs-3457	166	2	,	,	PUNCT
iajs-3457	166	3	r.	r.	PROPN
iajs-3457	166	4	β	β	X
iajs-3457	166	5	-	-	PUNCT
iajs-3457	166	6	thalassemia	thalassemia	NOUN
iajs-3457	166	7	.	.	PUNCT
iajs-3457	167	1	genetics	genetic	NOUN
iajs-3457	167	2	in	in	ADP
iajs-3457	167	3	medicine	medicine	NOUN
iajs-3457	167	4	2017	2017	NUM
iajs-3457	167	5	,	,	PUNCT
iajs-3457	167	6	19(6	19(6	NUM
iajs-3457	167	7	)	)	PUNCT
iajs-3457	167	8	,	,	PUNCT
iajs-3457	167	9	609	609	NUM
iajs-3457	167	10	-	-	SYM
iajs-3457	167	11	619	619	NUM
iajs-3457	167	12	.	.	PUNCT
iajs-3457	168	1	https://www.nature.com/articles/gim2016173	https://www.nature.com/articles/gim2016173	PROPN
iajs-3457	168	2	.	.	PUNCT
iajs-3457	169	1	7	7	X
iajs-3457	169	2	.	.	X
iajs-3457	169	3	mettananda	mettananda	PROPN
iajs-3457	169	4	,	,	PUNCT
iajs-3457	169	5	s.	s.	PROPN
iajs-3457	169	6	;	;	PUNCT
iajs-3457	169	7	higgs	higgs	PROPN
iajs-3457	169	8	,	,	PUNCT
iajs-3457	169	9	d.r	d.r	PROPN
iajs-3457	169	10	.	.	NOUN
iajs-3457	169	11	molecular	molecular	ADJ
iajs-3457	169	12	basis	basis	NOUN
iajs-3457	169	13	and	and	CCONJ
iajs-3457	169	14	genetic	genetic	ADJ
iajs-3457	169	15	modifiers	modifier	NOUN
iajs-3457	169	16	of	of	ADP
iajs-3457	169	17	thalassemia	thalassemia	NOUN
iajs-3457	169	18	.	.	PUNCT
iajs-3457	170	1	hematology/	hematology/	NUM
iajs-3457	170	2	oncology	oncology	NOUN
iajs-3457	170	3	clinics	clinic	NOUN
iajs-3457	170	4	2018	2018	NUM
iajs-3457	170	5	,	,	PUNCT
iajs-3457	170	6	32(2	32(2	NUM
iajs-3457	170	7	)	)	PUNCT
iajs-3457	170	8	,	,	PUNCT
iajs-3457	170	9	177	177	NUM
iajs-3457	170	10	-	-	SYM
iajs-3457	170	11	191	191	NUM
iajs-3457	170	12	.	.	PUNCT
iajs-3457	170	13	https://doi.org/10.1016/j.hoc.2017.11.003	https://doi.org/10.1016/j.hoc.2017.11.003	PROPN
iajs-3457	170	14	.	.	PROPN
iajs-3457	170	15	8	8	NUM
iajs-3457	170	16	.	.	X
iajs-3457	170	17	tari	tari	PROPN
iajs-3457	170	18	,	,	PUNCT
iajs-3457	170	19	k.	k.	PROPN
iajs-3457	170	20	;	;	PUNCT
iajs-3457	170	21	valizadeh	valizadeh	NOUN
iajs-3457	170	22	ardalan	ardalan	NOUN
iajs-3457	170	23	,	,	PUNCT
iajs-3457	170	24	p.	p.	NOUN
iajs-3457	170	25	;	;	PUNCT
iajs-3457	170	26	abbaszadehdibavar	abbaszadehdibavar	NOUN
iajs-3457	170	27	,	,	PUNCT
iajs-3457	170	28	m.	m.	NOUN
iajs-3457	170	29	;	;	PUNCT
iajs-3457	170	30	atashi	atashi	PROPN
iajs-3457	170	31	,	,	PUNCT
iajs-3457	170	32	a.	a.	NOUN
iajs-3457	170	33	;	;	PUNCT
iajs-3457	170	34	jalili	jalili	NOUN
iajs-3457	170	35	,	,	PUNCT
iajs-3457	170	36	a.	a.	NOUN
iajs-3457	170	37	;	;	PUNCT
iajs-3457	170	38	gheidishahran	gheidishahran	ADJ
iajs-3457	170	39	,	,	PUNCT
iajs-3457	170	40	m.	m.	NOUN
iajs-3457	170	41	thalassemia	thalassemia	NOUN
iajs-3457	170	42	an	an	DET
iajs-3457	170	43	update	update	NOUN
iajs-3457	170	44	:	:	PUNCT
iajs-3457	171	1	molecular	molecular	ADJ
iajs-3457	171	2	basis	basis	NOUN
iajs-3457	171	3	,	,	PUNCT
iajs-3457	171	4	clinical	clinical	ADJ
iajs-3457	171	5	features	feature	NOUN
iajs-3457	171	6	and	and	CCONJ
iajs-3457	171	7	treatment	treatment	NOUN
iajs-3457	171	8	.	.	PUNCT
iajs-3457	172	1	international	international	ADJ
iajs-3457	172	2	journal	journal	PROPN
iajs-3457	172	3	of	of	ADP
iajs-3457	172	4	biomedicine	biomedicine	NOUN
iajs-3457	172	5	and	and	CCONJ
iajs-3457	172	6	public	public	ADJ
iajs-3457	172	7	health	health	NOUN
iajs-3457	172	8	2018	2018	NUM
iajs-3457	172	9	,	,	PUNCT
iajs-3457	172	10	1(1	1(1	NUM
iajs-3457	172	11	)	)	PUNCT
iajs-3457	172	12	,	,	PUNCT
iajs-3457	172	13	48	48	NUM
iajs-3457	172	14	-	-	SYM
iajs-3457	172	15	58	58	NUM
iajs-3457	172	16	.	.	PUNCT
iajs-3457	173	1	https://doi.org/10.22631/ijbmph.2018.56102	https://doi.org/10.22631/ijbmph.2018.56102	PROPN
iajs-3457	173	2	.	.	NOUN
iajs-3457	173	3	9	9	NUM
iajs-3457	173	4	.	.	X
iajs-3457	173	5	kosaryan	kosaryan	PROPN
iajs-3457	173	6	,	,	PUNCT
iajs-3457	173	7	m.	m.	NOUN
iajs-3457	173	8	;	;	PUNCT
iajs-3457	173	9	karami	karami	PROPN
iajs-3457	173	10	,	,	PUNCT
iajs-3457	173	11	h.	h.	PROPN
iajs-3457	173	12	;	;	PUNCT
iajs-3457	173	13	darvishi	darvishi	PROPN
iajs-3457	173	14	-	-	PUNCT
iajs-3457	173	15	khezri	khezri	PROPN
iajs-3457	173	16	,	,	PUNCT
iajs-3457	173	17	h.	h.	PROPN
iajs-3457	173	18	;	;	PUNCT
iajs-3457	173	19	akbarzadeh	akbarzadeh	PROPN
iajs-3457	173	20	,	,	PUNCT
iajs-3457	173	21	r.	r.	PROPN
iajs-3457	173	22	;	;	PUNCT
iajs-3457	173	23	aliasgharian	aliasgharian	PROPN
iajs-3457	173	24	,	,	PUNCT
iajs-3457	173	25	a.	a.	NOUN
iajs-3457	173	26	;	;	PUNCT
iajs-3457	173	27	bromand	bromand	PROPN
iajs-3457	173	28	,	,	PUNCT
iajs-3457	173	29	k.	k.	PROPN
iajs-3457	173	30	treatment	treatment	NOUN
iajs-3457	173	31	status	status	NOUN
iajs-3457	173	32	of	of	ADP
iajs-3457	173	33	patients	patient	NOUN
iajs-3457	173	34	with	with	ADP
iajs-3457	173	35	b	b	NOUN
iajs-3457	173	36	-	-	PUNCT
iajs-3457	173	37	thalassemia	thalassemia	NOUN
iajs-3457	173	38	major	major	NOUN
iajs-3457	173	39	in	in	ADP
iajs-3457	173	40	northern	northern	ADJ
iajs-3457	173	41	iran	iran	PROPN
iajs-3457	173	42	:	:	PUNCT
iajs-3457	173	43	thalassemia	thalassemia	NOUN
iajs-3457	173	44	registry	registry	NOUN
iajs-3457	173	45	system	system	NOUN
iajs-3457	173	46	.	.	PUNCT
iajs-3457	174	1	iranian	iranian	ADJ
iajs-3457	174	2	journal	journal	PROPN
iajs-3457	174	3	of	of	ADP
iajs-3457	174	4	public	public	ADJ
iajs-3457	174	5	health	health	NOUN
iajs-3457	174	6	2019	2019	NUM
iajs-3457	174	7	,	,	PUNCT
iajs-3457	174	8	48(7	48(7	NUM
iajs-3457	174	9	)	)	PUNCT
iajs-3457	174	10	,	,	PUNCT
iajs-3457	174	11	1335.-1345	1335.-1345	NUM
iajs-3457	174	12	.	.	PUNCT
iajs-3457	175	1	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6708530	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6708530	PROPN
iajs-3457	175	2	.	.	PUNCT
iajs-3457	176	1	10	10	NUM
iajs-3457	176	2	.	.	PUNCT
iajs-3457	177	1	ćujić	ćujić	PROPN
iajs-3457	177	2	,	,	PUNCT
iajs-3457	177	3	d.	d.	PROPN
iajs-3457	177	4	;	;	PUNCT
iajs-3457	177	5	stefanoska	stefanoska	PROPN
iajs-3457	177	6	,	,	PUNCT
iajs-3457	177	7	i.	i.	PROPN
iajs-3457	177	8	;	;	PUNCT
iajs-3457	177	9	golubović	golubović	PROPN
iajs-3457	177	10	,	,	PUNCT
iajs-3457	177	11	s.	s.	PROPN
iajs-3457	177	12	serum	serum	PROPN
iajs-3457	177	13	ferritin	ferritin	ADJ
iajs-3457	177	14	in	in	ADP
iajs-3457	177	15	healthy	healthy	ADJ
iajs-3457	177	16	women	woman	NOUN
iajs-3457	177	17	and	and	CCONJ
iajs-3457	177	18	breast	breast	NOUN
iajs-3457	177	19	cancer	cancer	NOUN
iajs-3457	177	20	patients	patient	NOUN
iajs-3457	177	21	.	.	PUNCT
iajs-3457	178	1	journal	journal	PROPN
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iajs-3457	178	5	2011	2011	NUM
iajs-3457	178	6	,	,	PUNCT
iajs-3457	178	7	30(1	30(1	NUM
iajs-3457	178	8	)	)	PUNCT
iajs-3457	178	9	,	,	PUNCT
iajs-3457	178	10	33	33	NUM
iajs-3457	178	11	-	-	SYM
iajs-3457	178	12	37	37	NUM
iajs-3457	178	13	.	.	PUNCT
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iajs-3457	179	2	.	.	PUNCT
iajs-3457	180	1	11	11	NUM
iajs-3457	180	2	.	.	PUNCT
iajs-3457	181	1	fan	fan	PROPN
iajs-3457	181	2	,	,	PUNCT
iajs-3457	181	3	k.	k.	PROPN
iajs-3457	181	4	;	;	PUNCT
iajs-3457	181	5	gao	gao	PROPN
iajs-3457	181	6	,	,	PUNCT
iajs-3457	181	7	l.	l.	PROPN
iajs-3457	181	8	;	;	PUNCT
iajs-3457	181	9	yan	yan	PROPN
iajs-3457	181	10	,	,	PUNCT
iajs-3457	181	11	x.	x.	PROPN
iajs-3457	181	12	human	human	PROPN
iajs-3457	181	13	ferritin	ferritin	PROPN
iajs-3457	181	14	for	for	ADP
iajs-3457	181	15	tumor	tumor	NOUN
iajs-3457	181	16	detection	detection	NOUN
iajs-3457	181	17	and	and	CCONJ
iajs-3457	181	18	therapy	therapy	NOUN
iajs-3457	181	19	.	.	PUNCT
iajs-3457	182	1	wiley	wiley	PROPN
iajs-3457	182	2	interdisciplinary	interdisciplinary	ADJ
iajs-3457	182	3	reviews	review	NOUN
iajs-3457	182	4	:	:	PUNCT
iajs-3457	182	5	nanomedicine	nanomedicine	NOUN
iajs-3457	182	6	and	and	CCONJ
iajs-3457	182	7	nanobiotechnology	nanobiotechnology	NOUN
iajs-3457	182	8	2013	2013	NUM
iajs-3457	182	9	,	,	PUNCT
iajs-3457	182	10	5(4	5(4	NUM
iajs-3457	182	11	)	)	PUNCT
iajs-3457	182	12	,	,	PUNCT
iajs-3457	182	13	287	287	NUM
iajs-3457	182	14	-	-	SYM
iajs-3457	182	15	298	298	NUM
iajs-3457	182	16	.	.	PUNCT
iajs-3457	183	1	https://doi.org/10.1002/wnan.1221	https://doi.org/10.1002/wnan.1221	NOUN
iajs-3457	183	2	.	.	PUNCT
iajs-3457	184	1	https://doi.org/10.4274/jcrpe.galenos.2018.2018.0074	https://doi.org/10.4274/jcrpe.galenos.2018.2018.0074	PROPN
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iajs-3457	184	3	https://doi.org/10.1111/nyas.13037	https://doi.org/10.1111/nyas.13037	PROPN
iajs-3457	184	4	https://ijs.uobaghdad.edu.iq/index.php/eijs/article/view/6182	https://ijs.uobaghdad.edu.iq/index.php/eijs/article/view/6182	PROPN
iajs-3457	184	5	https://www.nature.com/articles/gim2016173	https://www.nature.com/articles/gim2016173	PROPN
iajs-3457	184	6	https://doi.org/10.1016/j.hoc.2017.11.003	https://doi.org/10.1016/j.hoc.2017.11.003	PROPN
iajs-3457	184	7	https://doi.org/10.22631/ijbmph.2018.56102	https://doi.org/10.22631/ijbmph.2018.56102	PROPN
iajs-3457	184	8	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6708530	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6708530	NOUN
iajs-3457	184	9	https://doi.org/10.2478/v10011-010-0027-6	https://doi.org/10.2478/v10011-010-0027-6	NUM
iajs-3457	184	10	https://doi.org/10.1002/wnan.1221	https://doi.org/10.1002/wnan.1221	NOUN
iajs-3457	184	11	ihjpas	ihjpa	VERB
iajs-3457	184	12	.	.	PUNCT
iajs-3457	185	1	2024	2024	NUM
iajs-3457	185	2	,	,	PUNCT
iajs-3457	185	3	37(4	37(4	NOUN
iajs-3457	185	4	)	)	PUNCT
iajs-3457	185	5	42	42	NUM
iajs-3457	185	6	12	12	NUM
iajs-3457	185	7	.	.	PUNCT
iajs-3457	186	1	estevão	estevão	NOUN
iajs-3457	186	2	,	,	PUNCT
iajs-3457	186	3	i.f	i.f	PROPN
iajs-3457	186	4	.	.	PROPN
iajs-3457	186	5	;	;	PUNCT
iajs-3457	186	6	peitl	peitl	PROPN
iajs-3457	186	7	,	,	PUNCT
iajs-3457	186	8	j.	j.	PROPN
iajs-3457	186	9	;	;	PUNCT
iajs-3457	186	10	bonini	bonini	PROPN
iajs-3457	186	11	-	-	PUNCT
iajs-3457	186	12	domingos	domingos	PROPN
iajs-3457	186	13	,	,	PUNCT
iajs-3457	186	14	c.r	c.r	PROPN
iajs-3457	186	15	.	.	PROPN
iajs-3457	186	16	serum	serum	PROPN
iajs-3457	186	17	ferritin	ferritin	ADJ
iajs-3457	186	18	and	and	CCONJ
iajs-3457	186	19	transferrin	transferrin	ADJ
iajs-3457	186	20	saturation	saturation	NOUN
iajs-3457	186	21	levels	level	NOUN
iajs-3457	186	22	in	in	ADP
iajs-3457	186	23	β0	β0	ADJ
iajs-3457	186	24	and	and	CCONJ
iajs-3457	186	25	β+	β+	PUNCT
iajs-3457	186	26	thalassemia	thalassemia	NOUN
iajs-3457	186	27	patients	patient	NOUN
iajs-3457	186	28	.	.	PUNCT
iajs-3457	187	1	genetics	genetic	NOUN
iajs-3457	187	2	and	and	CCONJ
iajs-3457	187	3	molecular	molecular	ADJ
iajs-3457	187	4	research	research	NOUN
iajs-3457	187	5	2011	2011	NUM
iajs-3457	187	6	,	,	PUNCT
iajs-3457	187	7	10(2	10(2	NUM
iajs-3457	187	8	)	)	PUNCT
iajs-3457	187	9	,	,	PUNCT
iajs-3457	187	10	632	632	NUM
iajs-3457	187	11	-	-	SYM
iajs-3457	187	12	639	639	NUM
iajs-3457	187	13	.	.	PUNCT
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iajs-3457	188	2	.	.	PROPN
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iajs-3457	188	4	.	.	X
iajs-3457	189	1	nehring	nehring	NOUN
iajs-3457	189	2	,	,	PUNCT
iajs-3457	189	3	s.m	s.m	PROPN
iajs-3457	189	4	.	.	PROPN
iajs-3457	189	5	;	;	PUNCT
iajs-3457	190	1	goyal	goyal	PROPN
iajs-3457	190	2	,	,	PUNCT
iajs-3457	190	3	a.	a.	NOUN
iajs-3457	190	4	;	;	PUNCT
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iajs-3457	190	6	,	,	PUNCT
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iajs-3457	190	8	;	;	PUNCT
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iajs-3457	191	3	-	-	PUNCT
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iajs-3457	191	6	.	.	PUNCT
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iajs-3457	192	3	.	.	PUNCT
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iajs-3457	193	3	,	,	PUNCT
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iajs-3457	193	5	.	.	PUNCT
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iajs-3457	194	3	.	.	PUNCT
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iajs-3457	195	2	,	,	PUNCT
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iajs-3457	195	4	;	;	PUNCT
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iajs-3457	195	6	,	,	PUNCT
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iajs-3457	195	12	and	and	CCONJ
iajs-3457	195	13	the	the	DET
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iajs-3457	195	15	of	of	ADP
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iajs-3457	195	17	.	.	PUNCT
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iajs-3457	196	4	,	,	PUNCT
iajs-3457	196	5	56(1	56(1	NUM
iajs-3457	196	6	)	)	PUNCT
iajs-3457	196	7	,	,	PUNCT
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iajs-3457	196	9	-	-	SYM
iajs-3457	196	10	142	142	NUM
iajs-3457	196	11	.	.	PUNCT
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iajs-3457	197	2	.	.	PUNCT
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iajs-3457	198	2	.	.	X
iajs-3457	199	1	moftah	moftah	PROPN
iajs-3457	199	2	,	,	PUNCT
iajs-3457	199	3	w.	w.	PROPN
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iajs-3457	199	5	;	;	PUNCT
iajs-3457	199	6	mohammed	mohammed	PROPN
iajs-3457	199	7	,	,	PUNCT
iajs-3457	199	8	e.	e.	PROPN
iajs-3457	199	9	k.	k.	PROPN
iajs-3457	199	10	;	;	PUNCT
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iajs-3457	199	15	;	;	PUNCT
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iajs-3457	199	17	,	,	PUNCT
iajs-3457	199	18	a.a	a.a	PROPN
iajs-3457	199	19	.	.	PROPN
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iajs-3457	199	23	and	and	CCONJ
iajs-3457	199	24	c	c	NOUN
iajs-3457	199	25	reactive	reactive	ADJ
iajs-3457	199	26	protein	protein	NOUN
iajs-3457	199	27	in	in	ADP
iajs-3457	199	28	children	child	NOUN
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iajs-3457	199	30	β	β	NOUN
iajs-3457	199	31	-	-	PUNCT
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iajs-3457	199	34	.	.	PUNCT
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iajs-3457	200	5	2020	2020	NUM
iajs-3457	200	6	,	,	PUNCT
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iajs-3457	200	8	)	)	PUNCT
iajs-3457	200	9	,	,	PUNCT
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iajs-3457	200	11	.	.	PUNCT
iajs-3457	201	1	https://www.scirp.org/journal/paperinformation?paperid=102691	https://www.scirp.org/journal/paperinformation?paperid=102691	PROPN
iajs-3457	201	2	.	.	PUNCT
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iajs-3457	202	2	.	.	PUNCT
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iajs-3457	203	2	,	,	PUNCT
iajs-3457	203	3	f.	f.	PROPN
iajs-3457	203	4	;	;	PUNCT
iajs-3457	203	5	joca	joca	PROPN
iajs-3457	203	6	,	,	PUNCT
iajs-3457	203	7	s.	s.	PROPN
iajs-3457	203	8	;	;	PUNCT
iajs-3457	203	9	nagy	nagy	ADJ
iajs-3457	203	10	-	-	PUNCT
iajs-3457	203	11	grócz	grócz	ADJ
iajs-3457	203	12	,	,	PUNCT
iajs-3457	203	13	g.	g.	PROPN
iajs-3457	203	14	;	;	PUNCT
iajs-3457	203	15	dvorácskó	dvorácskó	PROPN
iajs-3457	203	16	,	,	PUNCT
iajs-3457	203	17	s.	s.	PROPN
iajs-3457	203	18	;	;	PUNCT
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iajs-3457	203	20	,	,	PUNCT
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iajs-3457	203	22	;	;	PUNCT
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iajs-3457	203	24	,	,	PUNCT
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iajs-3457	203	26	;	;	PUNCT
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iajs-3457	203	28	,	,	PUNCT
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iajs-3457	203	31	cytokines	cytokine	NOUN
iajs-3457	203	32	:	:	PUNCT
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iajs-3457	203	34	links	link	NOUN
iajs-3457	203	35	between	between	ADP
iajs-3457	203	36	the	the	DET
iajs-3457	203	37	endocannabinoid	endocannabinoid	NOUN
iajs-3457	203	38	system	system	NOUN
iajs-3457	203	39	and	and	CCONJ
iajs-3457	203	40	the	the	DET
iajs-3457	203	41	kynurenine	kynurenine	NOUN
iajs-3457	203	42	pathway	pathway	NOUN
iajs-3457	203	43	in	in	ADP
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iajs-3457	203	45	.	.	PUNCT
iajs-3457	204	1	international	international	ADJ
iajs-3457	204	2	journal	journal	NOUN
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iajs-3457	204	5	sciences	science	NOUN
iajs-3457	204	6	2021	2021	NUM
iajs-3457	204	7	,	,	PUNCT
iajs-3457	204	8	22(11	22(11	NUM
iajs-3457	204	9	)	)	PUNCT
iajs-3457	204	10	,	,	PUNCT
iajs-3457	204	11	5903	5903	NUM
iajs-3457	204	12	.	.	PUNCT
iajs-3457	205	1	https://doi.org/10.3390/ijms22115903	https://doi.org/10.3390/ijms22115903	NOUN
iajs-3457	205	2	.	.	PUNCT
iajs-3457	206	1	17	17	NUM
iajs-3457	206	2	.	.	PUNCT
iajs-3457	207	1	d’orazi	d’orazi	PROPN
iajs-3457	207	2	,	,	PUNCT
iajs-3457	207	3	g.	g.	PROPN
iajs-3457	207	4	;	;	PUNCT
iajs-3457	207	5	cordani	cordani	PROPN
iajs-3457	207	6	,	,	PUNCT
iajs-3457	207	7	m.	m.	NOUN
iajs-3457	207	8	;	;	PUNCT
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iajs-3457	207	10	,	,	PUNCT
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iajs-3457	207	12	oncogenic	oncogenic	ADJ
iajs-3457	207	13	pathways	pathway	NOUN
iajs-3457	207	14	activated	activate	VERB
iajs-3457	207	15	by	by	ADP
iajs-3457	207	16	pro	pro	ADJ
iajs-3457	207	17	-	-	ADJ
iajs-3457	207	18	inflammatory	inflammatory	ADJ
iajs-3457	207	19	cytokines	cytokine	NOUN
iajs-3457	207	20	promote	promote	VERB
iajs-3457	207	21	mutant	mutant	ADJ
iajs-3457	207	22	p53	p53	NOUN
iajs-3457	207	23	stability	stability	NOUN
iajs-3457	207	24	:	:	PUNCT
iajs-3457	207	25	clue	clue	NOUN
iajs-3457	207	26	for	for	ADP
iajs-3457	207	27	novel	novel	ADJ
iajs-3457	207	28	anticancer	anticancer	NOUN
iajs-3457	207	29	therapies	therapy	NOUN
iajs-3457	207	30	.	.	PUNCT
iajs-3457	208	1	cellular	cellular	ADJ
iajs-3457	208	2	and	and	CCONJ
iajs-3457	208	3	molecular	molecular	ADJ
iajs-3457	208	4	life	life	NOUN
iajs-3457	208	5	sciences	science	NOUN
iajs-3457	208	6	2021	2021	NUM
iajs-3457	208	7	,	,	PUNCT
iajs-3457	208	8	78(5	78(5	NOUN
iajs-3457	208	9	)	)	PUNCT
iajs-3457	208	10	,	,	PUNCT
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iajs-3457	208	12	-	-	SYM
iajs-3457	208	13	1860	1860	NUM
iajs-3457	208	14	.	.	PUNCT
iajs-3457	209	1	https://doi.org/10.1007/s00018-020-03677-7	https://doi.org/10.1007/s00018-020-03677-7	NUM
iajs-3457	209	2	.	.	PUNCT
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iajs-3457	210	2	.	.	PUNCT
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iajs-3457	210	4	,	,	PUNCT
iajs-3457	210	5	p.	p.	PROPN
iajs-3457	210	6	;	;	PUNCT
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iajs-3457	210	8	,	,	PUNCT
iajs-3457	210	9	p.	p.	PROPN
iajs-3457	210	10	;	;	PUNCT
iajs-3457	210	11	mahapatra	mahapatra	PROPN
iajs-3457	210	12	,	,	PUNCT
iajs-3457	210	13	t.k	t.k	PROPN
iajs-3457	210	14	.	.	PROPN
iajs-3457	211	1	an	an	DET
iajs-3457	211	2	overview	overview	NOUN
iajs-3457	211	3	of	of	ADP
iajs-3457	211	4	cytokines	cytokine	NOUN
iajs-3457	211	5	;	;	PUNCT
iajs-3457	211	6	their	their	PRON
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iajs-3457	211	8	status	status	NOUN
iajs-3457	211	9	and	and	CCONJ
iajs-3457	211	10	futuristic	futuristic	ADJ
iajs-3457	211	11	scope	scope	NOUN
iajs-3457	211	12	.	.	PUNCT
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iajs-3457	212	2	university	university	PROPN
iajs-3457	212	3	journal	journal	PROPN
iajs-3457	212	4	of	of	ADP
iajs-3457	212	5	health	health	PROPN
iajs-3457	212	6	sciences	science	NOUN
iajs-3457	212	7	2017	2017	NUM
iajs-3457	212	8	,	,	PUNCT
iajs-3457	212	9	3(2	3(2	NUM
iajs-3457	212	10	)	)	PUNCT
iajs-3457	212	11	,	,	PUNCT
iajs-3457	212	12	50	50	NUM
iajs-3457	212	13	-	-	SYM
iajs-3457	212	14	53	53	NUM
iajs-3457	212	15	.	.	PUNCT
iajs-3457	213	1	https://doi.org/10.18231/2455-1732.2017.0016	https://doi.org/10.18231/2455-1732.2017.0016	PROPN
iajs-3457	213	2	.	.	PUNCT
iajs-3457	214	1	19	19	NUM
iajs-3457	214	2	.	.	PUNCT
iajs-3457	214	3	van	van	PROPN
iajs-3457	214	4	den	den	PROPN
iajs-3457	214	5	eeckhout	eeckhout	PROPN
iajs-3457	214	6	,	,	PUNCT
iajs-3457	214	7	b.	b.	PROPN
iajs-3457	214	8	;	;	PUNCT
iajs-3457	214	9	tavernier	tavernier	PROPN
iajs-3457	214	10	,	,	PUNCT
iajs-3457	214	11	j.	j.	PROPN
iajs-3457	214	12	;	;	PUNCT
iajs-3457	214	13	gerlo	gerlo	VERB
iajs-3457	214	14	,	,	PUNCT
iajs-3457	214	15	s.	s.	PROPN
iajs-3457	214	16	interleukin-1	interleukin-1	NUM
iajs-3457	214	17	as	as	ADP
iajs-3457	214	18	innate	innate	ADJ
iajs-3457	214	19	mediator	mediator	NOUN
iajs-3457	214	20	of	of	ADP
iajs-3457	214	21	t	t	PROPN
iajs-3457	214	22	cell	cell	NOUN
iajs-3457	214	23	immunity	immunity	NOUN
iajs-3457	214	24	.	.	PUNCT
iajs-3457	215	1	frontiers	frontier	NOUN
iajs-3457	215	2	in	in	ADP
iajs-3457	215	3	immunology	immunology	NOUN
iajs-3457	215	4	2021	2021	NUM
iajs-3457	215	5	,	,	PUNCT
iajs-3457	215	6	11	11	NUM
iajs-3457	215	7	,	,	PUNCT
iajs-3457	215	8	621931	621931	NUM
iajs-3457	215	9	.	.	PUNCT
iajs-3457	216	1	https://doi.org/10.3389/fimmu.2020.621931	https://doi.org/10.3389/fimmu.2020.621931	PROPN
iajs-3457	216	2	.	.	PROPN
iajs-3457	216	3	20	20	NUM
iajs-3457	216	4	.	.	PUNCT
iajs-3457	217	1	gupta	gupta	PROPN
iajs-3457	217	2	,	,	PUNCT
iajs-3457	217	3	u.p	u.p	PROPN
iajs-3457	217	4	.	.	PROPN
iajs-3457	217	5	;	;	PUNCT
iajs-3457	217	6	fucharoen	fucharoen	NOUN
iajs-3457	217	7	,	,	PUNCT
iajs-3457	217	8	p.	p.	NOUN
iajs-3457	217	9	;	;	PUNCT
iajs-3457	217	10	tanyong	tanyong	PROPN
iajs-3457	217	11	,	,	PUNCT
iajs-3457	217	12	d.i	d.i	PROPN
iajs-3457	217	13	.	.	PROPN
iajs-3457	217	14	interleukin-1	interleukin-1	NOUN
iajs-3457	217	15	involved	involve	VERB
iajs-3457	217	16	in	in	ADP
iajs-3457	217	17	apoptosis	apoptosis	NOUN
iajs-3457	217	18	of	of	ADP
iajs-3457	217	19	betathalassemia	betathalassemia	NOUN
iajs-3457	217	20	/	/	SYM
iajs-3457	217	21	hemoglobin	hemoglobin	NOUN
iajs-3457	217	22	e	e	NOUN
iajs-3457	217	23	erythroid	erythroid	ADJ
iajs-3457	217	24	progenitor	progenitor	NOUN
iajs-3457	217	25	cells	cell	NOUN
iajs-3457	217	26	.	.	PUNCT
iajs-3457	218	1	asian	asian	ADJ
iajs-3457	218	2	journal	journal	PROPN
iajs-3457	218	3	of	of	ADP
iajs-3457	218	4	medical	medical	ADJ
iajs-3457	218	5	sciences	science	NOUN
iajs-3457	218	6	2012	2012	NUM
iajs-3457	218	7	,	,	PUNCT
iajs-3457	218	8	3(4	3(4	NUM
iajs-3457	218	9	)	)	PUNCT
iajs-3457	218	10	,	,	PUNCT
iajs-3457	218	11	8	8	NUM
iajs-3457	218	12	-	-	SYM
iajs-3457	218	13	14	14	NUM
iajs-3457	218	14	.	.	PUNCT
iajs-3457	219	1	https://doi.org/10.3126/ajms.v3i4.6805	https://doi.org/10.3126/ajms.v3i4.6805	PROPN
iajs-3457	219	2	.	.	NOUN
iajs-3457	219	3	21	21	NUM
iajs-3457	219	4	.	.	PUNCT
iajs-3457	220	1	schmidt	schmidt	PROPN
iajs-3457	220	2	-	-	PUNCT
iajs-3457	220	3	arras	arras	PROPN
iajs-3457	220	4	,	,	PUNCT
iajs-3457	220	5	d.	d.	PROPN
iajs-3457	220	6	;	;	PUNCT
iajs-3457	220	7	rose	rose	PROPN
iajs-3457	220	8	-	-	PUNCT
iajs-3457	220	9	john	john	PROPN
iajs-3457	220	10	,	,	PUNCT
iajs-3457	220	11	s.	s.	PROPN
iajs-3457	220	12	il-6	il-6	PART
iajs-3457	220	13	pathway	pathway	NOUN
iajs-3457	220	14	in	in	ADP
iajs-3457	220	15	the	the	DET
iajs-3457	220	16	liver	liver	NOUN
iajs-3457	220	17	:	:	PUNCT
iajs-3457	220	18	from	from	ADP
iajs-3457	220	19	physiopathology	physiopathology	NOUN
iajs-3457	220	20	to	to	ADP
iajs-3457	220	21	therapy	therapy	NOUN
iajs-3457	220	22	.	.	PUNCT
iajs-3457	221	1	journal	journal	PROPN
iajs-3457	221	2	of	of	ADP
iajs-3457	221	3	hepatology	hepatology	NOUN
iajs-3457	221	4	2016	2016	NUM
iajs-3457	221	5	,	,	PUNCT
iajs-3457	221	6	64(6	64(6	NUM
iajs-3457	221	7	)	)	PUNCT
iajs-3457	221	8	,	,	PUNCT
iajs-3457	221	9	1403	1403	NUM
iajs-3457	221	10	-	-	SYM
iajs-3457	221	11	1415	1415	NUM
iajs-3457	221	12	.	.	PUNCT
iajs-3457	222	1	https://doi.org/10.1016/j.jhep.2016.02.004	https://doi.org/10.1016/j.jhep.2016.02.004	PROPN
iajs-3457	222	2	22	22	NUM
iajs-3457	222	3	.	.	PUNCT
iajs-3457	223	1	tanaka	tanaka	PROPN
iajs-3457	223	2	,	,	PUNCT
iajs-3457	223	3	t.	t.	PROPN
iajs-3457	223	4	;	;	PUNCT
iajs-3457	223	5	narazaki	narazaki	PROPN
iajs-3457	223	6	,	,	PUNCT
iajs-3457	223	7	m.	m.	NOUN
iajs-3457	223	8	;	;	PUNCT
iajs-3457	223	9	kishimoto	kishimoto	PROPN
iajs-3457	223	10	,	,	PUNCT
iajs-3457	223	11	t.	t.	PROPN
iajs-3457	223	12	il-6	il-6	NOUN
iajs-3457	223	13	in	in	ADP
iajs-3457	223	14	inflammation	inflammation	NOUN
iajs-3457	223	15	,	,	PUNCT
iajs-3457	223	16	immunity	immunity	NOUN
iajs-3457	223	17	,	,	PUNCT
iajs-3457	223	18	and	and	CCONJ
iajs-3457	223	19	disease	disease	NOUN
iajs-3457	223	20	.	.	PUNCT
iajs-3457	224	1	cold	cold	ADJ
iajs-3457	224	2	spring	spring	NOUN
iajs-3457	224	3	harbor	harbor	NOUN
iajs-3457	224	4	perspectives	perspective	NOUN
iajs-3457	224	5	in	in	ADP
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iajs-3457	224	7	2014	2014	NUM
iajs-3457	224	8	,	,	PUNCT
iajs-3457	224	9	6(10	6(10	NUM
iajs-3457	224	10	)	)	PUNCT
iajs-3457	224	11	,	,	PUNCT
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iajs-3457	225	2	.	.	PUNCT
iajs-3457	225	3	https://doi.org/10.1101/cshperspect.a016295	https://doi.org/10.1101/cshperspect.a016295	PROPN
iajs-3457	225	4	.	.	PROPN
iajs-3457	226	1	23	23	NUM
iajs-3457	226	2	.	.	X
iajs-3457	227	1	oztürk	oztürk	PROPN
iajs-3457	227	2	,	,	PUNCT
iajs-3457	227	3	o.	o.	PROPN
iajs-3457	227	4	;	;	PUNCT
iajs-3457	227	5	yaylim	yaylim	PROPN
iajs-3457	227	6	,	,	PUNCT
iajs-3457	227	7	i.	i.	NOUN
iajs-3457	227	8	;	;	PUNCT
iajs-3457	227	9	aydin	aydin	NOUN
iajs-3457	227	10	,	,	PUNCT
iajs-3457	227	11	m.	m.	NOUN
iajs-3457	227	12	;	;	PUNCT
iajs-3457	227	13	yilmaz	yilmaz	PROPN
iajs-3457	227	14	,	,	PUNCT
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iajs-3457	227	16	;	;	PUNCT
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iajs-3457	227	18	,	,	PUNCT
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iajs-3457	227	20	;	;	PUNCT
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iajs-3457	227	22	,	,	PUNCT
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iajs-3457	227	24	;	;	PUNCT
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iajs-3457	227	26	,	,	PUNCT
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iajs-3457	227	30	levels	level	NOUN
iajs-3457	227	31	of	of	ADP
iajs-3457	227	32	interleukin-6	interleukin-6	NUM
iajs-3457	227	33	and	and	CCONJ
iajs-3457	227	34	interleukin-8	interleukin-8	PRON
iajs-3457	227	35	in	in	ADP
iajs-3457	227	36	beta	beta	NOUN
iajs-3457	227	37	-	-	PUNCT
iajs-3457	227	38	thalassaemia	thalassaemia	NOUN
iajs-3457	227	39	major	major	NOUN
iajs-3457	227	40	.	.	PUNCT
iajs-3457	228	1	haematologia	haematologia	PROPN
iajs-3457	228	2	2001	2001	NUM
iajs-3457	228	3	,	,	PUNCT
iajs-3457	228	4	31(3	31(3	NUM
iajs-3457	228	5	)	)	PUNCT
iajs-3457	228	6	,	,	PUNCT
iajs-3457	228	7	237244	237244	NUM
iajs-3457	228	8	.	.	PUNCT
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iajs-3457	229	2	.	.	PUNCT
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iajs-3457	230	2	.	.	PUNCT
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iajs-3457	231	2	,	,	PUNCT
iajs-3457	231	3	i.	i.	PROPN
iajs-3457	231	4	;	;	PUNCT
iajs-3457	231	5	mancarella	mancarella	NOUN
iajs-3457	231	6	,	,	PUNCT
iajs-3457	231	7	m.	m.	NOUN
iajs-3457	231	8	;	;	PUNCT
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iajs-3457	231	10	,	,	PUNCT
iajs-3457	231	11	a.	a.	PROPN
iajs-3457	231	12	;	;	PUNCT
iajs-3457	231	13	vicenzi	vicenzi	PROPN
iajs-3457	231	14	,	,	PUNCT
iajs-3457	231	15	m.	m.	NOUN
iajs-3457	231	16	;	;	PUNCT
iajs-3457	231	17	cappellini	cappellini	PROPN
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iajs-3457	231	28	in	in	ADP
iajs-3457	231	29	patients	patient	NOUN
iajs-3457	231	30	with	with	ADP
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iajs-3457	231	32	-	-	NOUN
iajs-3457	231	33	thalassemia	thalassemia	NOUN
iajs-3457	231	34	.	.	PUNCT
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iajs-3457	232	2	review	review	NOUN
iajs-3457	232	3	of	of	ADP
iajs-3457	232	4	hematology	hematology	NOUN
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iajs-3457	232	6	,	,	PUNCT
iajs-3457	232	7	13(1	13(1	NUM
iajs-3457	232	8	)	)	PUNCT
iajs-3457	232	9	,	,	PUNCT
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iajs-3457	232	11	–	–	PUNCT
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iajs-3457	232	13	.	.	PUNCT
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iajs-3457	233	2	.	.	PROPN
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iajs-3457	234	2	.	.	PUNCT
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iajs-3457	235	7	,	,	PUNCT
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iajs-3457	235	9	;	;	PUNCT
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iajs-3457	235	14	;	;	PUNCT
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iajs-3457	235	20	and	and	CCONJ
iajs-3457	235	21	biochemical	biochemical	ADJ
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iajs-3457	235	23	of	of	ADP
iajs-3457	235	24	beta	beta	NOUN
iajs-3457	235	25	-	-	PUNCT
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iajs-3457	236	6	oncology	oncology	NOUN
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iajs-3457	236	8	stem	stem	NOUN
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iajs-3457	236	11	2020	2020	NUM
iajs-3457	236	12	,	,	PUNCT
iajs-3457	236	13	10(1	10(1	NUM
iajs-3457	236	14	)	)	PUNCT
iajs-3457	236	15	,	,	PUNCT
iajs-3457	236	16	7	7	X
iajs-3457	236	17	.	.	NUM
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iajs-3457	236	19	26	26	NUM
iajs-3457	236	20	.	.	PUNCT
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iajs-3457	237	2	,	,	PUNCT
iajs-3457	237	3	e.	e.	PROPN
iajs-3457	237	4	;	;	PUNCT
iajs-3457	237	5	taghipour	taghipour	NOUN
iajs-3457	237	6	,	,	PUNCT
iajs-3457	237	7	m.	m.	NOUN
iajs-3457	237	8	;	;	PUNCT
iajs-3457	237	9	zucconi	zucconi	PROPN
iajs-3457	237	10	,	,	PUNCT
iajs-3457	237	11	b.e	b.e	PROPN
iajs-3457	237	12	.	.	PROPN
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iajs-3457	237	14	of	of	ADP
iajs-3457	237	15	different	different	ADJ
iajs-3457	237	16	rbc	rbc	PROPN
iajs-3457	237	17	indices	index	NOUN
iajs-3457	237	18	and	and	CCONJ
iajs-3457	237	19	formulas	formula	NOUN
iajs-3457	237	20	in	in	ADP
iajs-3457	237	21	discriminating	discriminate	VERB
iajs-3457	237	22	between	between	ADP
iajs-3457	237	23	β	β	NOUN
iajs-3457	237	24	-	-	NOUN
iajs-3457	237	25	thalassemia	thalassemia	VERB
iajs-3457	237	26	minor	minor	ADJ
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iajs-3457	237	28	other	other	ADJ
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iajs-3457	237	30	hypochromic	hypochromic	ADJ
iajs-3457	237	31	cases	case	NOUN
iajs-3457	237	32	.	.	PUNCT
iajs-3457	238	1	mediterranean	mediterranean	PROPN
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iajs-3457	238	5	and	and	CCONJ
iajs-3457	238	6	infectious	infectious	ADJ
iajs-3457	238	7	diseases	disease	NOUN
iajs-3457	238	8	2015	2015	NUM
iajs-3457	238	9	,	,	PUNCT
iajs-3457	238	10	7(1	7(1	NUM
iajs-3457	238	11	)	)	PUNCT
iajs-3457	238	12	.	.	PUNCT
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iajs-3457	239	2	.	.	PUNCT
iajs-3457	240	1	27	27	NUM
iajs-3457	240	2	.	.	PUNCT
iajs-3457	241	1	ribeil	ribeil	PROPN
iajs-3457	241	2	,	,	PUNCT
iajs-3457	241	3	j.a	j.a	PROPN
iajs-3457	241	4	.	.	PROPN
iajs-3457	241	5	;	;	PUNCT
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iajs-3457	241	7	,	,	PUNCT
iajs-3457	241	8	j.b	j.b	PROPN
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iajs-3457	241	10	;	;	PUNCT
iajs-3457	241	11	dussiot	dussiot	NOUN
iajs-3457	241	12	,	,	PUNCT
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iajs-3457	241	14	;	;	PUNCT
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iajs-3457	241	18	i.	i.	PROPN
iajs-3457	241	19	;	;	PUNCT
iajs-3457	241	20	courtois	courtois	PROPN
iajs-3457	241	21	,	,	PUNCT
iajs-3457	241	22	g.	g.	PROPN
iajs-3457	241	23	;	;	PUNCT
iajs-3457	241	24	hermine	hermine	PROPN
iajs-3457	241	25	,	,	PUNCT
iajs-3457	241	26	o.	o.	PROPN
iajs-3457	241	27	ineffective	ineffective	ADJ
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iajs-3457	242	9	394295	394295	NUM
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iajs-3457	242	11	,	,	PUNCT
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iajs-3457	242	13	.	.	PUNCT
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iajs-3457	243	2	.	.	PUNCT
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iajs-3457	244	5	;	;	PUNCT
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iajs-3457	244	19	.	.	PUNCT
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iajs-3457	245	10	)	)	PUNCT
iajs-3457	245	11	,	,	PUNCT
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iajs-3457	245	13	.	.	PUNCT
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iajs-3457	248	6	https://doi.org/10.1080/17474086.2020.1686354	https://doi.org/10.1080/17474086.2020.1686354	X
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iajs-3457	249	5	ihjpas	ihjpas	PROPN
iajs-3457	249	6	.	.	PUNCT
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iajs-3457	250	2	,	,	PUNCT
iajs-3457	250	3	37(4	37(4	NOUN
iajs-3457	250	4	)	)	PUNCT
iajs-3457	250	5	43	43	NUM
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iajs-3457	250	7	.	.	PUNCT
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iajs-3457	251	2	,	,	PUNCT
iajs-3457	251	3	n.	n.	PROPN
iajs-3457	251	4	;	;	PUNCT
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iajs-3457	251	6	,	,	PUNCT
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iajs-3457	251	8	;	;	PUNCT
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iajs-3457	251	10	-	-	PUNCT
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iajs-3457	251	14	;	;	PUNCT
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iajs-3457	251	16	,	,	PUNCT
iajs-3457	251	17	v.	v.	ADV
iajs-3457	251	18	;	;	PUNCT
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iajs-3457	251	44	:	:	PUNCT
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iajs-3457	252	7	-	-	SYM
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iajs-3457	252	9	.	.	PUNCT
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iajs-3457	253	2	.	.	PUNCT
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iajs-3457	254	2	.	.	PUNCT
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iajs-3457	255	4	;	;	PUNCT
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iajs-3457	255	8	;	;	PUNCT
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iajs-3457	256	8	,	,	PUNCT
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iajs-3457	256	10	)	)	PUNCT
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iajs-3457	257	2	.	.	PROPN
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iajs-3457	257	4	.	.	PUNCT
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iajs-3457	258	18	;	;	PUNCT
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iajs-3457	260	8	,	,	PUNCT
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iajs-3457	260	10	)	)	PUNCT
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iajs-3457	260	13	-	-	SYM
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iajs-3457	263	14	-	-	SYM
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iajs-3457	263	16	.	.	PUNCT
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iajs-3457	265	8	;	;	PUNCT
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iajs-3457	265	10	,	,	PUNCT
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iajs-3457	265	14	serum	serum	NOUN
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iajs-3457	265	16	level	level	NOUN
iajs-3457	265	17	,	,	PUNCT
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iajs-3457	265	20	sgpt	sgpt	NOUN
iajs-3457	265	21	and	and	CCONJ
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iajs-3457	269	9	)	)	PUNCT
iajs-3457	269	10	,	,	PUNCT
iajs-3457	269	11	323	323	NUM
iajs-3457	269	12	-	-	SYM
iajs-3457	269	13	328	328	NUM
iajs-3457	269	14	.	.	PUNCT
iajs-3457	270	1	http://dx.doi.org/10.20902/ijctr.2018.110738	http://dx.doi.org/10.20902/ijctr.2018.110738	NOUN
iajs-3457	270	2	.	.	PUNCT
iajs-3457	271	1	35	35	NUM
iajs-3457	271	2	.	.	X
iajs-3457	272	1	moftah	moftah	PROPN
iajs-3457	272	2	,	,	PUNCT
iajs-3457	272	3	w.m	w.m	PROPN
iajs-3457	272	4	.	.	PROPN
iajs-3457	272	5	;	;	PUNCT
iajs-3457	272	6	mohammed	mohammed	PROPN
iajs-3457	272	7	,	,	PUNCT
iajs-3457	272	8	e.k	e.k	PROPN
iajs-3457	272	9	.	.	PROPN
iajs-3457	272	10	;	;	PUNCT
iajs-3457	272	11	morsy	morsy	PROPN
iajs-3457	272	12	,	,	PUNCT
iajs-3457	272	13	a.a	a.a	PROPN
iajs-3457	272	14	.	.	PROPN
iajs-3457	272	15	;	;	PUNCT
iajs-3457	272	16	ibrahim	ibrahim	PROPN
iajs-3457	272	17	,	,	PUNCT
iajs-3457	272	18	a.a	a.a	PROPN
iajs-3457	272	19	.	.	PROPN
iajs-3457	272	20	ischemia	ischemia	NOUN
iajs-3457	272	21	modified	modify	VERB
iajs-3457	272	22	albumin	albumin	NOUN
iajs-3457	272	23	and	and	CCONJ
iajs-3457	272	24	c	c	NOUN
iajs-3457	272	25	reactive	reactive	ADJ
iajs-3457	272	26	protein	protein	NOUN
iajs-3457	272	27	in	in	ADP
iajs-3457	272	28	children	child	NOUN
iajs-3457	272	29	with	with	ADP
iajs-3457	272	30	β	β	NOUN
iajs-3457	272	31	-	-	PUNCT
iajs-3457	272	32	thalassemia	thalassemia	ADJ
iajs-3457	272	33	major	major	NOUN
iajs-3457	272	34	.	.	PUNCT
iajs-3457	273	1	open	open	ADJ
iajs-3457	273	2	journal	journal	NOUN
iajs-3457	273	3	of	of	ADP
iajs-3457	273	4	pediatrics	pediatric	NOUN
iajs-3457	273	5	2020	2020	NUM
iajs-3457	273	6	,	,	PUNCT
iajs-3457	273	7	10(03	10(03	NUM
iajs-3457	273	8	)	)	PUNCT
iajs-3457	273	9	,	,	PUNCT
iajs-3457	273	10	452	452	NUM
iajs-3457	273	11	.	.	PUNCT
iajs-3457	274	1	https://doi.org/10.4236/ojped.2020.103046	https://doi.org/10.4236/ojped.2020.103046	PROPN
iajs-3457	274	2	.	.	PROPN
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iajs-3457	275	2	.	.	PUNCT
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iajs-3457	276	2	,	,	PUNCT
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iajs-3457	276	4	estimation	estimation	NOUN
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iajs-3457	276	6	mda	mda	PROPN
iajs-3457	276	7	,	,	PUNCT
iajs-3457	276	8	crp	crp	PROPN
iajs-3457	276	9	and	and	CCONJ
iajs-3457	276	10	some	some	DET
iajs-3457	276	11	hematological	hematological	ADJ
iajs-3457	276	12	parameters	parameter	NOUN
iajs-3457	276	13	in	in	ADP
iajs-3457	276	14	the	the	DET
iajs-3457	276	15	mature	mature	ADJ
iajs-3457	276	16	cypriot	cypriot	ADJ
iajs-3457	276	17	thalassemia	thalassemia	NOUN
iajs-3457	276	18	patients	patient	NOUN
iajs-3457	276	19	.	.	PUNCT
iajs-3457	277	1	zanco	zanco	PROPN
iajs-3457	277	2	journal	journal	PROPN
iajs-3457	277	3	of	of	ADP
iajs-3457	277	4	pure	pure	ADJ
iajs-3457	277	5	and	and	CCONJ
iajs-3457	277	6	applied	apply	VERB
iajs-3457	277	7	sciences	science	NOUN
iajs-3457	277	8	2019	2019	NUM
iajs-3457	277	9	,	,	PUNCT
iajs-3457	277	10	31(s4	31(s4	NUM
iajs-3457	277	11	)	)	PUNCT
iajs-3457	277	12	,	,	PUNCT
iajs-3457	277	13	143–149	143–149	NUM
iajs-3457	277	14	.	.	PUNCT
iajs-3457	278	1	https://doi.org/10.21271/zjpas.31.s4.23	https://doi.org/10.21271/zjpas.31.s4.23	X
iajs-3457	278	2	.	.	PUNCT
iajs-3457	279	1	37	37	NUM
iajs-3457	279	2	.	.	PUNCT
iajs-3457	279	3	kanavaki	kanavaki	PROPN
iajs-3457	279	4	,	,	PUNCT
iajs-3457	279	5	i.	i.	PROPN
iajs-3457	279	6	;	;	PUNCT
iajs-3457	279	7	makrythanasis	makrythanasis	NOUN
iajs-3457	279	8	,	,	PUNCT
iajs-3457	279	9	p.	p.	NOUN
iajs-3457	279	10	;	;	PUNCT
iajs-3457	279	11	lazaropoulou	lazaropoulou	PROPN
iajs-3457	279	12	,	,	PUNCT
iajs-3457	279	13	c.	c.	PROPN
iajs-3457	279	14	;	;	PUNCT
iajs-3457	279	15	tsironi	tsironi	NOUN
iajs-3457	279	16	,	,	PUNCT
iajs-3457	279	17	m.	m.	NOUN
iajs-3457	279	18	;	;	PUNCT
iajs-3457	279	19	kattamis	kattamis	PROPN
iajs-3457	279	20	,	,	PUNCT
iajs-3457	279	21	a.	a.	NOUN
iajs-3457	279	22	;	;	PUNCT
iajs-3457	279	23	rombos	rombos	PROPN
iajs-3457	279	24	,	,	PUNCT
iajs-3457	279	25	i.	i.	NOUN
iajs-3457	279	26	;	;	PUNCT
iajs-3457	279	27	papassotiriou	papassotiriou	PROPN
iajs-3457	279	28	,	,	PUNCT
iajs-3457	279	29	i.	i.	NOUN
iajs-3457	279	30	soluble	soluble	ADJ
iajs-3457	279	31	endothelial	endothelial	NOUN
iajs-3457	279	32	adhesion	adhesion	NOUN
iajs-3457	279	33	molecules	molecule	NOUN
iajs-3457	279	34	and	and	CCONJ
iajs-3457	279	35	inflammation	inflammation	NOUN
iajs-3457	279	36	markers	marker	NOUN
iajs-3457	279	37	in	in	ADP
iajs-3457	279	38	patients	patient	NOUN
iajs-3457	279	39	with	with	ADP
iajs-3457	279	40	β	β	X
iajs-3457	279	41	-	-	PUNCT
iajs-3457	279	42	thalassemia	thalassemia	ADJ
iajs-3457	279	43	intermedia	intermedia	PROPN
iajs-3457	279	44	.	.	PUNCT
iajs-3457	279	45	blood	blood	NOUN
iajs-3457	279	46	cells	cell	NOUN
iajs-3457	279	47	,	,	PUNCT
iajs-3457	279	48	molecules	molecule	NOUN
iajs-3457	279	49	,	,	PUNCT
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iajs-3457	279	52	2009	2009	NUM
iajs-3457	279	53	,	,	PUNCT
iajs-3457	279	54	43(3	43(3	NUM
iajs-3457	279	55	)	)	PUNCT
iajs-3457	279	56	.	.	PUNCT
iajs-3457	280	1	https://doi.org/10.1016/j.bcmd.2009.06.002	https://doi.org/10.1016/j.bcmd.2009.06.002	NOUN
iajs-3457	280	2	.	.	PUNCT
iajs-3457	281	1	38	38	NUM
iajs-3457	281	2	.	.	PUNCT
iajs-3457	282	1	kyriakou	kyriakou	PROPN
iajs-3457	282	2	,	,	PUNCT
iajs-3457	282	3	d.	d.	PROPN
iajs-3457	282	4	;	;	PUNCT
iajs-3457	282	5	alexandrakis	alexandrakis	PROPN
iajs-3457	282	6	,	,	PUNCT
iajs-3457	282	7	m.	m.	NOUN
iajs-3457	282	8	;	;	PUNCT
iajs-3457	282	9	kyriakou	kyriakou	PROPN
iajs-3457	282	10	,	,	PUNCT
iajs-3457	282	11	e.	e.	PROPN
iajs-3457	282	12	;	;	PUNCT
iajs-3457	282	13	liapi	liapi	ADV
iajs-3457	282	14	,	,	PUNCT
iajs-3457	282	15	d.	d.	PROPN
iajs-3457	282	16	;	;	PUNCT
iajs-3457	282	17	kourelis	kourelis	PROPN
iajs-3457	282	18	,	,	PUNCT
iajs-3457	282	19	t.	t.	PROPN
iajs-3457	282	20	;	;	PUNCT
iajs-3457	282	21	passam	passam	PROPN
iajs-3457	282	22	,	,	PUNCT
iajs-3457	282	23	f.	f.	PROPN
iajs-3457	282	24	;	;	PUNCT
iajs-3457	282	25	papadakis	papadakis	PROPN
iajs-3457	282	26	,	,	PUNCT
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iajs-3457	282	30	blood	blood	NOUN
iajs-3457	282	31	and	and	CCONJ
iajs-3457	282	32	endothelial	endothelial	ADJ
iajs-3457	282	33	cells	cell	NOUN
iajs-3457	282	34	in	in	ADP
iajs-3457	282	35	thalassemia	thalassemia	NOUN
iajs-3457	282	36	patients	patient	NOUN
iajs-3457	282	37	.	.	PUNCT
iajs-3457	283	1	annals	annal	NOUN
iajs-3457	283	2	of	of	ADP
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iajs-3457	283	4	2001	2001	NUM
iajs-3457	283	5	,	,	PUNCT
iajs-3457	283	6	80	80	NUM
iajs-3457	283	7	,	,	PUNCT
iajs-3457	283	8	577	577	NUM
iajs-3457	283	9	-	-	SYM
iajs-3457	283	10	583	583	NUM
iajs-3457	283	11	.	.	PUNCT
iajs-3457	284	1	https://doi.org/10.1007/s002770100355	https://doi.org/10.1007/s002770100355	NUM
iajs-3457	284	2	.	.	PUNCT
iajs-3457	284	3	39	39	NUM
iajs-3457	284	4	.	.	PUNCT
iajs-3457	285	1	wanachiwanawin	wanachiwanawin	PROPN
iajs-3457	285	2	,	,	PUNCT
iajs-3457	285	3	w.	w.	PROPN
iajs-3457	285	4	;	;	PUNCT
iajs-3457	285	5	wiener	wiener	NOUN
iajs-3457	285	6	,	,	PUNCT
iajs-3457	285	7	e.	e.	PROPN
iajs-3457	285	8	;	;	PUNCT
iajs-3457	285	9	siripanyaphinyo	siripanyaphinyo	PROPN
iajs-3457	285	10	,	,	PUNCT
iajs-3457	285	11	u.	u.	PROPN
iajs-3457	285	12	;	;	PUNCT
iajs-3457	285	13	chinprasertsuk	chinprasertsuk	NOUN
iajs-3457	285	14	,	,	PUNCT
iajs-3457	285	15	s.	s.	PROPN
iajs-3457	285	16	;	;	PUNCT
iajs-3457	285	17	mawas	mawas	PROPN
iajs-3457	285	18	,	,	PUNCT
iajs-3457	285	19	f.	f.	PROPN
iajs-3457	285	20	;	;	PUNCT
iajs-3457	285	21	fucharoen	fucharoen	PROPN
iajs-3457	285	22	,	,	PUNCT
iajs-3457	285	23	s.	s.	PROPN
iajs-3457	285	24	;	;	PUNCT
iajs-3457	285	25	visudhiphan	visudhiphan	PROPN
iajs-3457	285	26	,	,	PUNCT
iajs-3457	285	27	s.	s.	PROPN
iajs-3457	285	28	serum	serum	PROPN
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iajs-3457	285	30	of	of	ADP
iajs-3457	285	31	tumor	tumor	NOUN
iajs-3457	285	32	necrosis	necrosis	NOUN
iajs-3457	285	33	factor	factor	NOUN
iajs-3457	285	34	-	-	PUNCT
iajs-3457	285	35	alpha	alpha	NOUN
iajs-3457	285	36	,	,	PUNCT
iajs-3457	285	37	interleukin-1	interleukin-1	NOUN
iajs-3457	285	38	,	,	PUNCT
iajs-3457	285	39	and	and	CCONJ
iajs-3457	285	40	interferongamma	interferongamma	PROPN
iajs-3457	285	41	in	in	ADP
iajs-3457	285	42	beta	beta	NOUN
iajs-3457	285	43	-	-	PUNCT
iajs-3457	285	44	thalassemia	thalassemia	NOUN
iajs-3457	285	45	/	/	SYM
iajs-3457	285	46	hbe	hbe	NOUN
iajs-3457	285	47	and	and	CCONJ
iajs-3457	285	48	their	their	PRON
iajs-3457	285	49	clinical	clinical	ADJ
iajs-3457	285	50	significance	significance	NOUN
iajs-3457	285	51	.	.	PUNCT
iajs-3457	286	1	journal	journal	NOUN
iajs-3457	286	2	of	of	ADP
iajs-3457	286	3	interferon	interferon	PROPN
iajs-3457	286	4	&	&	CCONJ
iajs-3457	286	5	cytokine	cytokine	PROPN
iajs-3457	286	6	research	research	NOUN
iajs-3457	286	7	1999	1999	NUM
iajs-3457	286	8	,	,	PUNCT
iajs-3457	286	9	19(2	19(2	NUM
iajs-3457	286	10	)	)	PUNCT
iajs-3457	286	11	,	,	PUNCT
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iajs-3457	286	13	-	-	SYM
iajs-3457	286	14	111	111	NUM
iajs-3457	286	15	.	.	PUNCT
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iajs-3457	287	2	.	.	PUNCT
iajs-3457	288	1	40	40	NUM
iajs-3457	288	2	.	.	PUNCT
iajs-3457	289	1	sajid	sajid	PROPN
iajs-3457	289	2	,	,	PUNCT
iajs-3457	289	3	h.	h.	PROPN
iajs-3457	289	4	;	;	PUNCT
iajs-3457	289	5	bilal	bilal	PROPN
iajs-3457	289	6	,	,	PUNCT
iajs-3457	289	7	a.z	a.z	PROPN
iajs-3457	289	8	.	.	PROPN
iajs-3457	289	9	;	;	PUNCT
iajs-3457	289	10	namoos	namoos	PROPN
iajs-3457	289	11	,	,	PUNCT
iajs-3457	289	12	k.	k.	PROPN
iajs-3457	289	13	;	;	PUNCT
iajs-3457	289	14	iqtidar	iqtidar	VERB
iajs-3457	289	15	,	,	PUNCT
iajs-3457	289	16	a.	a.	NOUN
iajs-3457	289	17	;	;	PUNCT
iajs-3457	289	18	zaidi	zaidi	PROPN
iajs-3457	289	19	,	,	PUNCT
iajs-3457	289	20	i.a	i.a	PROPN
iajs-3457	289	21	.	.	PROPN
iajs-3457	289	22	;	;	PUNCT
iajs-3457	289	23	asghar	asghar	PROPN
iajs-3457	289	24	,	,	PUNCT
iajs-3457	289	25	a.	a.	NOUN
iajs-3457	289	26	study	study	NOUN
iajs-3457	289	27	of	of	ADP
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iajs-3457	289	29	of	of	ADP
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iajs-3457	289	31	interleukin-1	interleukin-1	NOUN
iajs-3457	289	32	beta	beta	NOUN
iajs-3457	289	33	levels	level	NOUN
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iajs-3457	289	35	β	β	X
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iajs-3457	289	37	major	major	ADJ
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iajs-3457	289	41	and	and	CCONJ
iajs-3457	289	42	impaired	impaired	ADJ
iajs-3457	289	43	glucose	glucose	NOUN
iajs-3457	289	44	tolerance	tolerance	NOUN
iajs-3457	289	45	.	.	PUNCT
iajs-3457	290	1	pakistan	pakistan	PROPN
iajs-3457	290	2	journal	journal	PROPN
iajs-3457	290	3	of	of	ADP
iajs-3457	290	4	medical	medical	PROPN
iajs-3457	290	5	&	&	CCONJ
iajs-3457	290	6	health	health	PROPN
iajs-3457	290	7	sciences	sciences	PROPN
iajs-3457	290	8	2019	2019	NUM
iajs-3457	290	9	,	,	PUNCT
iajs-3457	290	10	13	13	NUM
iajs-3457	290	11	,	,	PUNCT
iajs-3457	290	12	309	309	NUM
iajs-3457	290	13	-	-	SYM
iajs-3457	290	14	313	313	NUM
iajs-3457	290	15	.	.	PUNCT
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iajs-3457	291	2	.	.	PROPN
iajs-3457	292	1	41	41	NUM
iajs-3457	292	2	.	.	PUNCT
iajs-3457	293	1	el	el	NOUN
iajs-3457	293	2	-	-	PUNCT
iajs-3457	293	3	rasheidy	rasheidy	ADJ
iajs-3457	293	4	,	,	PUNCT
iajs-3457	293	5	f.h	f.h	PROPN
iajs-3457	293	6	.	.	PROPN
iajs-3457	293	7	;	;	PUNCT
iajs-3457	293	8	essa	essa	PROPN
iajs-3457	293	9	,	,	PUNCT
iajs-3457	293	10	e.s	e.s	PROPN
iajs-3457	293	11	.	.	PROPN
iajs-3457	293	12	;	;	PUNCT
iajs-3457	293	13	mahmoud	mahmoud	PROPN
iajs-3457	293	14	,	,	PUNCT
iajs-3457	293	15	a.a	a.a	PROPN
iajs-3457	293	16	.	.	PROPN
iajs-3457	293	17	;	;	PUNCT
iajs-3457	293	18	nada	nada	PROPN
iajs-3457	293	19	,	,	PUNCT
iajs-3457	293	20	a.e.w	a.e.w	PROPN
iajs-3457	293	21	.	.	PUNCT
iajs-3457	293	22	a.	a.	PROPN
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iajs-3457	293	24	serum	serum	NOUN
iajs-3457	293	25	adiponectin	adiponectin	NOUN
iajs-3457	293	26	is	be	AUX
iajs-3457	293	27	related	relate	VERB
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iajs-3457	293	29	elevated	elevate	VERB
iajs-3457	293	30	serum	serum	NOUN
iajs-3457	293	31	ferritin	ferritin	ADJ
iajs-3457	293	32	and	and	CCONJ
iajs-3457	293	33	interleukin-6	interleukin-6	NUM
iajs-3457	293	34	in	in	ADP
iajs-3457	293	35	β	β	ADJ
iajs-3457	293	36	-	-	ADJ
iajs-3457	293	37	thalassaemia	thalassaemia	ADJ
iajs-3457	293	38	major	major	ADJ
iajs-3457	293	39	children	child	NOUN
iajs-3457	293	40	.	.	PUNCT
iajs-3457	294	1	journal	journal	NOUN
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iajs-3457	294	4	endocrinology	endocrinology	NOUN
iajs-3457	294	5	and	and	CCONJ
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iajs-3457	294	8	,	,	PUNCT
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iajs-3457	294	10	)	)	PUNCT
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iajs-3457	294	13	-	-	SYM
iajs-3457	294	14	958	958	NUM
iajs-3457	294	15	.	.	PUNCT
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iajs-3457	295	2	.	.	PUNCT
iajs-3457	296	1	42	42	NUM
iajs-3457	296	2	.	.	PUNCT
iajs-3457	297	1	hassan	hassan	PROPN
iajs-3457	297	2	,	,	PUNCT
iajs-3457	297	3	a.m.	a.m.	ADV
iajs-3457	297	4	;	;	PUNCT
iajs-3457	297	5	rahman	rahman	PROPN
iajs-3457	297	6	,	,	PUNCT
iajs-3457	297	7	s	s	PART
iajs-3457	297	8	j.	j.	PROPN
iajs-3457	297	9	a.	a.	NOUN
iajs-3457	297	10	evaluation	evaluation	NOUN
iajs-3457	297	11	of	of	ADP
iajs-3457	297	12	liver	liver	NOUN
iajs-3457	297	13	enzymes	enzyme	NOUN
iajs-3457	297	14	,	,	PUNCT
iajs-3457	297	15	interleukin-6	interleukin-6	NUM
iajs-3457	297	16	and	and	CCONJ
iajs-3457	297	17	tumer	tumer	NOUN
iajs-3457	297	18	necrosis	necrosis	NOUN
iajs-3457	297	19	factoralpha	factoralpha	NOUN
iajs-3457	297	20	in	in	ADP
iajs-3457	297	21	children	child	NOUN
iajs-3457	297	22	suffering	suffer	VERB
iajs-3457	297	23	from	from	ADP
iajs-3457	297	24	thalassemia	thalassemia	NOUN
iajs-3457	297	25	and	and	CCONJ
iajs-3457	297	26	treated	treat	VERB
iajs-3457	297	27	with	with	ADP
iajs-3457	297	28	deferoxamine	deferoxamine	NOUN
iajs-3457	297	29	and	and	CCONJ
iajs-3457	297	30	deferasirox	deferasirox	VERB
iajs-3457	297	31	drug	drug	NOUN
iajs-3457	297	32	in	in	ADP
iajs-3457	297	33	kirkuk	kirkuk	PROPN
iajs-3457	297	34	city	city	PROPN
iajs-3457	297	35	.	.	PUNCT
iajs-3457	298	1	hiv	hiv	PROPN
iajs-3457	298	2	nursing	nurse	VERB
iajs-3457	298	3	2022	2022	NUM
iajs-3457	298	4	,	,	PUNCT
iajs-3457	298	5	22(2	22(2	NUM
iajs-3457	298	6	)	)	PUNCT
iajs-3457	298	7	,	,	PUNCT
iajs-3457	298	8	1461	1461	NUM
iajs-3457	298	9	-	-	SYM
iajs-3457	298	10	1465	1465	NUM
iajs-3457	298	11	.	.	PUNCT
iajs-3457	299	1	https://hivnursing.net/index.php/hiv/article/view/581	https://hivnursing.net/index.php/hiv/article/view/581	X
iajs-3457	299	2	.	.	PUNCT
iajs-3457	300	1	https://link.springer.com/article/10.1007/s12020-017-1435-x	https://link.springer.com/article/10.1007/s12020-017-1435-x	NUM
iajs-3457	300	2	https://link.springer.com/article/10.1007/s12020-017-1435-x	https://link.springer.com/article/10.1007/s12020-017-1435-x	NOUN
iajs-3457	300	3	https://doi.org/10.1002/9781119599586.ch	https://doi.org/10.1002/9781119599586.ch	X
iajs-3457	300	4	http://saber.ucv.ve/ojs/index.php/rev_aavft/article/view/25855	http://saber.ucv.ve/ojs/index.php/rev_aavft/article/view/25855	NOUN
iajs-3457	300	5	https://doi.org/10.18203/2320-6012.ijrms20180322	https://doi.org/10.18203/2320-6012.ijrms20180322	PROPN
iajs-3457	300	6	http://dx.doi.org/10.20902/ijctr.2018.110738	http://dx.doi.org/10.20902/ijctr.2018.110738	VERB
iajs-3457	300	7	https://doi.org/10.4236/ojped.2020.103046	https://doi.org/10.4236/ojped.2020.103046	PROPN
iajs-3457	300	8	https://doi.org/10.21271/zjpas.31.s4.23	https://doi.org/10.21271/zjpas.31.s4.23	PRON
iajs-3457	300	9	https://doi.org/10.1016/j.bcmd.2009.06.002	https://doi.org/10.1016/j.bcmd.2009.06.002	VERB
iajs-3457	300	10	https://doi.org/10.1007/s002770100355	https://doi.org/10.1007/s002770100355	NUM
iajs-3457	300	11	https://doi.org/10.1089/107999099314243	https://doi.org/10.1089/107999099314243	PROPN
iajs-3457	300	12	https://pjmhsonline.com/2019/april_june/pdf/309.pdf	https://pjmhsonline.com/2019/april_june/pdf/309.pdf	NOUN
iajs-3457	300	13	https://doi.org/10.1515/jpem-2016-0014	https://doi.org/10.1515/jpem-2016-0014	X
iajs-3457	300	14	https://doi.org/10.1515/jpem-2016-0014	https://doi.org/10.1515/jpem-2016-0014	PUNCT
iajs-3457	300	15	https://hivnursing.net/index.php/hiv/article/view/581	https://hivnursing.net/index.php/hiv/article/view/581	NOUN
iajs-3457	300	16	ihjpas	ihjpa	NOUN
iajs-3457	300	17	.	.	PUNCT
iajs-3457	301	1	2024	2024	NUM
iajs-3457	301	2	,	,	PUNCT
iajs-3457	301	3	37(4	37(4	NOUN
iajs-3457	301	4	)	)	PUNCT
iajs-3457	301	5	44	44	NUM
iajs-3457	301	6	43	43	NUM
iajs-3457	301	7	.	.	PUNCT
iajs-3457	302	1	aggeli	aggeli	PROPN
iajs-3457	302	2	,	,	PUNCT
iajs-3457	302	3	c.	c.	NOUN
iajs-3457	302	4	;	;	PUNCT
iajs-3457	302	5	antoniades	antoniade	NOUN
iajs-3457	302	6	,	,	PUNCT
iajs-3457	302	7	c.	c.	PROPN
iajs-3457	302	8	;	;	PUNCT
iajs-3457	302	9	cosma	cosma	PROPN
iajs-3457	302	10	,	,	PUNCT
iajs-3457	302	11	c.	c.	PROPN
iajs-3457	302	12	;	;	PUNCT
iajs-3457	302	13	chrysohoou	chrysohoou	PROPN
iajs-3457	302	14	,	,	PUNCT
iajs-3457	302	15	c.	c.	NOUN
iajs-3457	302	16	;	;	PUNCT
iajs-3457	302	17	tousoulis	tousoulis	PROPN
iajs-3457	302	18	,	,	PUNCT
iajs-3457	302	19	d.	d.	PROPN
iajs-3457	302	20	;	;	PUNCT
iajs-3457	302	21	ladis	ladis	PROPN
iajs-3457	302	22	,	,	PUNCT
iajs-3457	302	23	v.	v.	PROPN
iajs-3457	302	24	;	;	PUNCT
iajs-3457	302	25	stefanadis	stefanadis	PROPN
iajs-3457	302	26	,	,	PUNCT
iajs-3457	302	27	c.	c.	NOUN
iajs-3457	302	28	endothelial	endothelial	ADJ
iajs-3457	302	29	dysfunction	dysfunction	NOUN
iajs-3457	302	30	and	and	CCONJ
iajs-3457	302	31	inflammatory	inflammatory	ADJ
iajs-3457	302	32	process	process	NOUN
iajs-3457	302	33	in	in	ADP
iajs-3457	302	34	transfusion	transfusion	NOUN
iajs-3457	302	35	-	-	PUNCT
iajs-3457	302	36	dependent	dependent	ADJ
iajs-3457	302	37	patients	patient	NOUN
iajs-3457	302	38	with	with	ADP
iajs-3457	302	39	betathalassemia	betathalassemia	PROPN
iajs-3457	302	40	major	major	PROPN
iajs-3457	302	41	.	.	PUNCT
iajs-3457	303	1	international	international	ADJ
iajs-3457	303	2	journal	journal	PROPN
iajs-3457	303	3	of	of	ADP
iajs-3457	303	4	cardiology	cardiology	NOUN
iajs-3457	303	5	2005	2005	NUM
iajs-3457	303	6	,	,	PUNCT
iajs-3457	303	7	105(1	105(1	NUM
iajs-3457	303	8	)	)	PUNCT
iajs-3457	303	9	,	,	PUNCT
iajs-3457	303	10	80	80	NUM
iajs-3457	303	11	-	-	SYM
iajs-3457	303	12	84	84	NUM
iajs-3457	303	13	.	.	PUNCT
iajs-3457	304	1	https://doi.org/10.1016/j.ijcard.2004.12.025	https://doi.org/10.1016/j.ijcard.2004.12.025	PROPN
iajs-3457	304	2	.	.	PUNCT
iajs-3457	305	1	https://doi.org/10.1016/j.ijcard.2004.12.025	https://doi.org/10.1016/j.ijcard.2004.12.025	PROPN