id	sid	tid	token	lemma	pos
iajs-3524	1	1	286	286	NUM
iajs-3524	1	2	©	©	ADP
iajs-3524	1	3	2024	2024	NUM
iajs-3524	1	4	the	the	DET
iajs-3524	1	5	author(s	author(s	NOUN
iajs-3524	1	6	)	)	PUNCT
iajs-3524	1	7	.	.	PUNCT
iajs-3524	2	1	published	publish	VERB
iajs-3524	2	2	by	by	ADP
iajs-3524	2	3	college	college	NOUN
iajs-3524	2	4	of	of	ADP
iajs-3524	2	5	education	education	NOUN
iajs-3524	2	6	for	for	ADP
iajs-3524	2	7	pure	pure	ADJ
iajs-3524	2	8	science	science	NOUN
iajs-3524	2	9	(	(	PUNCT
iajs-3524	2	10	ibn	ibn	PROPN
iajs-3524	2	11	al	al	PROPN
iajs-3524	2	12	-	-	PUNCT
iajs-3524	2	13	haitham	haitham	PROPN
iajs-3524	2	14	)	)	PUNCT
iajs-3524	2	15	,	,	PUNCT
iajs-3524	2	16	university	university	NOUN
iajs-3524	2	17	of	of	ADP
iajs-3524	2	18	baghdad	baghdad	PROPN
iajs-3524	2	19	.	.	PUNCT
iajs-3524	3	1	this	this	PRON
iajs-3524	3	2	is	be	AUX
iajs-3524	3	3	an	an	DET
iajs-3524	3	4	open	open	ADJ
iajs-3524	3	5	-	-	PUNCT
iajs-3524	3	6	access	access	NOUN
iajs-3524	3	7	article	article	NOUN
iajs-3524	3	8	distributed	distribute	VERB
iajs-3524	3	9	under	under	ADP
iajs-3524	3	10	the	the	DET
iajs-3524	3	11	terms	term	NOUN
iajs-3524	3	12	of	of	ADP
iajs-3524	3	13	the	the	DET
iajs-3524	3	14	creative	creative	ADJ
iajs-3524	3	15	commons	common	NOUN
iajs-3524	3	16	attribution	attribution	NOUN
iajs-3524	3	17	4.0	4.0	NUM
iajs-3524	3	18	international	international	ADJ
iajs-3524	3	19	license	license	NOUN
iajs-3524	3	20	ibn	ibn	PROPN
iajs-3524	3	21	al	al	PROPN
iajs-3524	3	22	-	-	PUNCT
iajs-3524	3	23	haitham	haitham	PROPN
iajs-3524	3	24	journal	journal	PROPN
iajs-3524	3	25	for	for	ADP
iajs-3524	3	26	pure	pure	ADJ
iajs-3524	3	27	and	and	CCONJ
iajs-3524	3	28	applied	applied	ADJ
iajs-3524	3	29	sciences	sciences	PROPN
iajs-3524	3	30	journal	journal	PROPN
iajs-3524	3	31	homepage	homepage	NOUN
iajs-3524	3	32	:	:	PUNCT
iajs-3524	3	33	jih.uobaghdad.edu.iq	jih.uobaghdad.edu.iq	NOUN
iajs-3524	3	34	pissn	pissn	ADJ
iajs-3524	3	35	:	:	PUNCT
iajs-3524	3	36	1609	1609	NUM
iajs-3524	3	37	-	-	SYM
iajs-3524	3	38	4042	4042	NUM
iajs-3524	3	39	,	,	PUNCT
iajs-3524	3	40	eissn	eissn	NOUN
iajs-3524	3	41	:	:	PUNCT
iajs-3524	3	42	2521	2521	NUM
iajs-3524	3	43	-	-	SYM
iajs-3524	3	44	3407	3407	NUM
iajs-3524	3	45	ihjpas	ihjpa	NOUN
iajs-3524	3	46	.	.	PUNCT
iajs-3524	4	1	2024	2024	NUM
iajs-3524	4	2	,	,	PUNCT
iajs-3524	4	3	37(4	37(4	X
iajs-3524	4	4	)	)	PUNCT
iajs-3524	4	5	study	study	NOUN
iajs-3524	4	6	of	of	ADP
iajs-3524	4	7	collagenase-3	collagenase-3	NUM
iajs-3524	4	8	levels	level	NOUN
iajs-3524	4	9	in	in	ADP
iajs-3524	4	10	rheumatoid	rheumatoid	NOUN
iajs-3524	4	11	arthritis	arthritis	NOUN
iajs-3524	4	12	patients	patient	NOUN
iajs-3524	4	13	with	with	ADP
iajs-3524	4	14	and	and	CCONJ
iajs-3524	4	15	without	without	ADP
iajs-3524	4	16	type	type	NOUN
iajs-3524	4	17	2	2	NUM
iajs-3524	4	18	diabetes	diabetes	NOUN
iajs-3524	4	19	mellitus	mellitus	PROPN
iajs-3524	4	20	nadia	nadia	PROPN
iajs-3524	4	21	abdul	abdul	PROPN
iajs-3524	4	22	-	-	PUNCT
iajs-3524	4	23	kareem	kareem	PROPN
iajs-3524	4	24	abdul	abdul	PROPN
iajs-3524	4	25	-	-	PUNCT
iajs-3524	4	26	zahra1	zahra1	PROPN
iajs-3524	4	27	*	*	PUNCT
iajs-3524	4	28	and	and	CCONJ
iajs-3524	4	29	zainab	zainab	PROPN
iajs-3524	4	30	m.	m.	PROPN
iajs-3524	4	31	al	al	PROPN
iajs-3524	4	32	-	-	PUNCT
iajs-3524	4	33	rubaei2	rubaei2	PROPN
iajs-3524	4	34	1,2	1,2	NUM
iajs-3524	4	35	department	department	NOUN
iajs-3524	4	36	of	of	ADP
iajs-3524	4	37	chemistry	chemistry	NOUN
iajs-3524	4	38	,	,	PUNCT
iajs-3524	4	39	college	college	NOUN
iajs-3524	4	40	of	of	ADP
iajs-3524	4	41	education	education	NOUN
iajs-3524	4	42	for	for	ADP
iajs-3524	4	43	pure	pure	ADJ
iajs-3524	4	44	science	science	NOUN
iajs-3524	4	45	(	(	PUNCT
iajs-3524	4	46	ibn	ibn	PROPN
iajs-3524	4	47	al	al	PROPN
iajs-3524	4	48	-	-	PUNCT
iajs-3524	4	49	haitham	haitham	PROPN
iajs-3524	4	50	)	)	PUNCT
iajs-3524	4	51	,	,	PUNCT
iajs-3524	4	52	university	university	NOUN
iajs-3524	4	53	of	of	ADP
iajs-3524	4	54	baghdad	baghdad	PROPN
iajs-3524	4	55	,	,	PUNCT
iajs-3524	4	56	baghdad	baghdad	PROPN
iajs-3524	4	57	,	,	PUNCT
iajs-3524	4	58	iraq	iraq	PROPN
iajs-3524	4	59	.	.	PUNCT
iajs-3524	5	1	*	*	PUNCT
iajs-3524	5	2	corresponding	correspond	VERB
iajs-3524	5	3	author	author	NOUN
iajs-3524	5	4	.	.	PUNCT
iajs-3524	6	1	received	receive	VERB
iajs-3524	6	2	:	:	PUNCT
iajs-3524	6	3	24	24	NUM
iajs-3524	6	4	may	may	PROPN
iajs-3524	6	5	2023	2023	NUM
iajs-3524	6	6	accepted	accept	VERB
iajs-3524	6	7	:	:	PUNCT
iajs-3524	6	8	9	9	NUM
iajs-3524	6	9	july	july	PROPN
iajs-3524	6	10	2023	2023	NUM
iajs-3524	6	11	published	publish	VERB
iajs-3524	6	12	:	:	PUNCT
iajs-3524	6	13	20	20	NUM
iajs-3524	6	14	october	october	NOUN
iajs-3524	6	15	2024	2024	NUM
iajs-3524	6	16	doi.org/10.30526/37.4.3524	doi.org/10.30526/37.4.3524	NOUN
iajs-3524	6	17	abstract	abstract	ADV
iajs-3524	6	18	this	this	DET
iajs-3524	6	19	research	research	NOUN
iajs-3524	6	20	sought	seek	VERB
iajs-3524	6	21	early	early	ADJ
iajs-3524	6	22	signs	sign	NOUN
iajs-3524	6	23	of	of	ADP
iajs-3524	6	24	type	type	NOUN
iajs-3524	6	25	2	2	NUM
iajs-3524	6	26	diabetes	diabetes	NOUN
iajs-3524	6	27	mellitus	mellitus	NOUN
iajs-3524	6	28	(	(	PUNCT
iajs-3524	6	29	t2	t2	NOUN
iajs-3524	6	30	dm	dm	PROPN
iajs-3524	6	31	)	)	PUNCT
iajs-3524	6	32	in	in	ADP
iajs-3524	6	33	rheumatoid	rheumatoid	NOUN
iajs-3524	6	34	arthritis	arthritis	NOUN
iajs-3524	6	35	(	(	PUNCT
iajs-3524	6	36	ra	ra	NOUN
iajs-3524	6	37	)	)	PUNCT
iajs-3524	6	38	patients	patient	NOUN
iajs-3524	6	39	.	.	PUNCT
iajs-3524	7	1	the	the	DET
iajs-3524	7	2	current	current	ADJ
iajs-3524	7	3	research	research	NOUN
iajs-3524	7	4	's	's	PART
iajs-3524	7	5	objectives	objective	NOUN
iajs-3524	7	6	are	be	AUX
iajs-3524	7	7	to	to	PART
iajs-3524	7	8	identify	identify	VERB
iajs-3524	7	9	collagenase-3	collagenase-3	NUM
iajs-3524	7	10	(	(	PUNCT
iajs-3524	7	11	cl-3	cl-3	NOUN
iajs-3524	7	12	)	)	PUNCT
iajs-3524	7	13	in	in	ADP
iajs-3524	7	14	ra	ra	PROPN
iajs-3524	7	15	patients	patient	NOUN
iajs-3524	7	16	with	with	ADP
iajs-3524	7	17	and	and	CCONJ
iajs-3524	7	18	without	without	ADP
iajs-3524	7	19	t2	t2	NOUN
iajs-3524	7	20	dm	dm	PROPN
iajs-3524	7	21	as	as	ADP
iajs-3524	7	22	a	a	DET
iajs-3524	7	23	disease	disease	NOUN
iajs-3524	7	24	complication	complication	NOUN
iajs-3524	7	25	,	,	PUNCT
iajs-3524	7	26	compare	compare	VERB
iajs-3524	7	27	these	these	DET
iajs-3524	7	28	findings	finding	NOUN
iajs-3524	7	29	to	to	ADP
iajs-3524	7	30	those	those	PRON
iajs-3524	7	31	of	of	ADP
iajs-3524	7	32	a	a	DET
iajs-3524	7	33	control	control	NOUN
iajs-3524	7	34	group	group	NOUN
iajs-3524	7	35	,	,	PUNCT
iajs-3524	7	36	and	and	CCONJ
iajs-3524	7	37	ascertain	ascertain	VERB
iajs-3524	7	38	whether	whether	SCONJ
iajs-3524	7	39	or	or	CCONJ
iajs-3524	7	40	not	not	PART
iajs-3524	7	41	cl-3	cl-3	AUX
iajs-3524	7	42	correlates	correlate	VERB
iajs-3524	7	43	with	with	ADP
iajs-3524	7	44	all	all	PRON
iajs-3524	7	45	of	of	ADP
iajs-3524	7	46	the	the	DET
iajs-3524	7	47	parameters	parameter	NOUN
iajs-3524	7	48	that	that	PRON
iajs-3524	7	49	were	be	AUX
iajs-3524	7	50	examined	examine	VERB
iajs-3524	7	51	in	in	ADP
iajs-3524	7	52	each	each	DET
iajs-3524	7	53	group	group	NOUN
iajs-3524	7	54	.	.	PUNCT
iajs-3524	8	1	in	in	ADP
iajs-3524	8	2	the	the	DET
iajs-3524	8	3	present	present	ADJ
iajs-3524	8	4	research	research	NOUN
iajs-3524	8	5	,	,	PUNCT
iajs-3524	8	6	(	(	PUNCT
iajs-3524	8	7	150	150	NUM
iajs-3524	8	8	)	)	PUNCT
iajs-3524	8	9	participants	participant	NOUN
iajs-3524	8	10	all	all	PRON
iajs-3524	8	11	between	between	ADP
iajs-3524	8	12	the	the	DET
iajs-3524	8	13	ages	age	NOUN
iajs-3524	8	14	of	of	ADP
iajs-3524	8	15	30	30	NUM
iajs-3524	8	16	and	and	CCONJ
iajs-3524	8	17	50	50	NUM
iajs-3524	8	18	were	be	AUX
iajs-3524	8	19	divided	divide	VERB
iajs-3524	8	20	into	into	ADP
iajs-3524	8	21	three	three	NUM
iajs-3524	8	22	groups	group	NOUN
iajs-3524	8	23	:	:	PUNCT
iajs-3524	8	24	(	(	PUNCT
iajs-3524	8	25	g1	g1	PROPN
iajs-3524	8	26	)	)	PUNCT
iajs-3524	8	27	control	control	NOUN
iajs-3524	8	28	(	(	PUNCT
iajs-3524	8	29	n=50	n=50	PROPN
iajs-3524	8	30	)	)	PUNCT
iajs-3524	8	31	,	,	PUNCT
iajs-3524	8	32	(	(	PUNCT
iajs-3524	8	33	g2	g2	PROPN
iajs-3524	8	34	)	)	PUNCT
iajs-3524	8	35	ra	ra	PROPN
iajs-3524	8	36	(	(	PUNCT
iajs-3524	8	37	n=50	n=50	PROPN
iajs-3524	8	38	)	)	PUNCT
iajs-3524	8	39	,	,	PUNCT
iajs-3524	8	40	and	and	CCONJ
iajs-3524	8	41	(	(	PUNCT
iajs-3524	8	42	g3	g3	PROPN
iajs-3524	8	43	)	)	PUNCT
iajs-3524	8	44	ra	ra	PROPN
iajs-3524	8	45	with	with	ADP
iajs-3524	8	46	t2	t2	PROPN
iajs-3524	8	47	dm	dm	X
iajs-3524	8	48	(	(	PUNCT
iajs-3524	8	49	n=50	n=50	PROPN
iajs-3524	8	50	)	)	PUNCT
iajs-3524	8	51	.	.	PUNCT
iajs-3524	9	1	collagenase-3	collagenase-3	PROPN
iajs-3524	9	2	,	,	PUNCT
iajs-3524	9	3	glycated	glycate	VERB
iajs-3524	9	4	hemoglobin	hemoglobin	NOUN
iajs-3524	9	5	(	(	PUNCT
iajs-3524	9	6	hba1c	hba1c	PROPN
iajs-3524	9	7	)	)	PUNCT
iajs-3524	9	8	,	,	PUNCT
iajs-3524	9	9	erythrocyte	erythrocyte	NOUN
iajs-3524	9	10	sedimentaion	sedimentaion	NOUN
iajs-3524	9	11	(	(	PUNCT
iajs-3524	9	12	esr	esr	PROPN
iajs-3524	9	13	)	)	PUNCT
iajs-3524	9	14	,	,	PUNCT
iajs-3524	9	15	anti	anti	ADJ
iajs-3524	9	16	-	-	ADJ
iajs-3524	9	17	cyclic	cyclic	ADJ
iajs-3524	9	18	citrullinated	citrullinate	VERB
iajs-3524	9	19	peptide	peptide	NOUN
iajs-3524	9	20	(	(	PUNCT
iajs-3524	9	21	anti	anti	ADJ
iajs-3524	9	22	-	-	ADJ
iajs-3524	9	23	ccp	ccp	X
iajs-3524	9	24	)	)	PUNCT
iajs-3524	9	25	,	,	PUNCT
iajs-3524	9	26	and	and	CCONJ
iajs-3524	9	27	rheumatoid	rheumatoid	NOUN
iajs-3524	9	28	factor	factor	NOUN
iajs-3524	9	29	(	(	PUNCT
iajs-3524	9	30	rf	rf	NOUN
iajs-3524	9	31	)	)	PUNCT
iajs-3524	9	32	were	be	AUX
iajs-3524	9	33	all	all	ADV
iajs-3524	9	34	measured	measure	VERB
iajs-3524	9	35	in	in	ADP
iajs-3524	9	36	this	this	DET
iajs-3524	9	37	experiment	experiment	NOUN
iajs-3524	9	38	.	.	PUNCT
iajs-3524	10	1	data	datum	NOUN
iajs-3524	10	2	revealed	reveal	VERB
iajs-3524	10	3	that	that	SCONJ
iajs-3524	10	4	(	(	PUNCT
iajs-3524	10	5	g2	g2	PROPN
iajs-3524	10	6	)	)	PUNCT
iajs-3524	10	7	and	and	CCONJ
iajs-3524	10	8	(	(	PUNCT
iajs-3524	10	9	g3	g3	NOUN
iajs-3524	10	10	)	)	PUNCT
iajs-3524	10	11	had	have	VERB
iajs-3524	10	12	considerably	considerably	ADV
iajs-3524	10	13	greater	great	ADJ
iajs-3524	10	14	rf	rf	ADJ
iajs-3524	10	15	,	,	PUNCT
iajs-3524	10	16	anti	anti	ADJ
iajs-3524	10	17	-	-	ADJ
iajs-3524	10	18	ccp	ccp	PROPN
iajs-3524	10	19	,	,	PUNCT
iajs-3524	10	20	and	and	CCONJ
iajs-3524	10	21	esr	esr	PROPN
iajs-3524	10	22	levels	level	NOUN
iajs-3524	10	23	than	than	ADP
iajs-3524	10	24	(	(	PUNCT
iajs-3524	10	25	g1	g1	PROPN
iajs-3524	10	26	)	)	PUNCT
iajs-3524	10	27	in	in	ADP
iajs-3524	10	28	comparison	comparison	NOUN
iajs-3524	10	29	.	.	PUNCT
iajs-3524	11	1	compared	compare	VERB
iajs-3524	11	2	to	to	ADP
iajs-3524	11	3	g2	g2	PROPN
iajs-3524	11	4	,	,	PUNCT
iajs-3524	11	5	there	there	PRON
iajs-3524	11	6	was	be	VERB
iajs-3524	11	7	a	a	DET
iajs-3524	11	8	very	very	ADV
iajs-3524	11	9	obvious	obvious	ADJ
iajs-3524	11	10	increase	increase	NOUN
iajs-3524	11	11	in	in	ADP
iajs-3524	11	12	g3	g3	PROPN
iajs-3524	11	13	.	.	PUNCT
iajs-3524	12	1	the	the	DET
iajs-3524	12	2	results	result	NOUN
iajs-3524	12	3	of	of	ADP
iajs-3524	12	4	the	the	DET
iajs-3524	12	5	hba1c	hba1c	PROPN
iajs-3524	12	6	test	test	NOUN
iajs-3524	12	7	showed	show	VERB
iajs-3524	12	8	that	that	SCONJ
iajs-3524	12	9	(	(	PUNCT
iajs-3524	12	10	g2	g2	PROPN
iajs-3524	12	11	)	)	PUNCT
iajs-3524	12	12	increased	increase	VERB
iajs-3524	12	13	non	non	ADJ
iajs-3524	12	14	-	-	ADJ
iajs-3524	12	15	significantly	significantly	ADV
iajs-3524	12	16	compared	compare	VERB
iajs-3524	12	17	to	to	ADP
iajs-3524	12	18	(	(	PUNCT
iajs-3524	12	19	g1	g1	PROPN
iajs-3524	12	20	)	)	PUNCT
iajs-3524	12	21	,	,	PUNCT
iajs-3524	12	22	but	but	CCONJ
iajs-3524	12	23	(	(	PUNCT
iajs-3524	12	24	g3	g3	NOUN
iajs-3524	12	25	)	)	PUNCT
iajs-3524	12	26	was	be	AUX
iajs-3524	12	27	much	much	ADV
iajs-3524	12	28	more	more	ADJ
iajs-3524	12	29	than	than	ADP
iajs-3524	12	30	(	(	PUNCT
iajs-3524	12	31	g2	g2	PROPN
iajs-3524	12	32	)	)	PUNCT
iajs-3524	12	33	and	and	CCONJ
iajs-3524	12	34	(	(	PUNCT
iajs-3524	12	35	g1	g1	PROPN
iajs-3524	12	36	)	)	PUNCT
iajs-3524	12	37	.	.	PUNCT
iajs-3524	13	1	the	the	DET
iajs-3524	13	2	levels	level	NOUN
iajs-3524	13	3	of	of	ADP
iajs-3524	13	4	cl-3	cl-3	PRON
iajs-3524	13	5	in	in	ADP
iajs-3524	13	6	(	(	PUNCT
iajs-3524	13	7	g2	g2	PROPN
iajs-3524	13	8	)	)	PUNCT
iajs-3524	13	9	and	and	CCONJ
iajs-3524	13	10	(	(	PUNCT
iajs-3524	13	11	g3	g3	NOUN
iajs-3524	13	12	)	)	PUNCT
iajs-3524	13	13	were	be	AUX
iajs-3524	13	14	found	find	VERB
iajs-3524	13	15	to	to	PART
iajs-3524	13	16	be	be	AUX
iajs-3524	13	17	significantly	significantly	ADV
iajs-3524	13	18	higher	high	ADJ
iajs-3524	13	19	than	than	ADP
iajs-3524	13	20	in	in	ADP
iajs-3524	13	21	controls	control	NOUN
iajs-3524	13	22	(	(	PUNCT
iajs-3524	13	23	g1	g1	PROPN
iajs-3524	13	24	)	)	PUNCT
iajs-3524	13	25	in	in	ADP
iajs-3524	13	26	these	these	DET
iajs-3524	13	27	groups	group	NOUN
iajs-3524	13	28	.	.	PUNCT
iajs-3524	14	1	a	a	DET
iajs-3524	14	2	well	well	ADV
iajs-3524	14	3	-	-	PUNCT
iajs-3524	14	4	related	relate	VERB
iajs-3524	14	5	biomarker	biomarker	NOUN
iajs-3524	14	6	with	with	ADP
iajs-3524	14	7	these	these	DET
iajs-3524	14	8	patients	patient	NOUN
iajs-3524	14	9	was	be	AUX
iajs-3524	14	10	shown	show	VERB
iajs-3524	14	11	by	by	ADP
iajs-3524	14	12	cl-3	cl-3	PROPN
iajs-3524	14	13	,	,	PUNCT
iajs-3524	14	14	demonstrating	demonstrate	VERB
iajs-3524	14	15	a	a	DET
iajs-3524	14	16	strong	strong	ADJ
iajs-3524	14	17	positive	positive	ADJ
iajs-3524	14	18	or	or	CCONJ
iajs-3524	14	19	negative	negative	ADJ
iajs-3524	14	20	association	association	NOUN
iajs-3524	14	21	with	with	ADP
iajs-3524	14	22	all	all	DET
iajs-3524	14	23	metrics	metric	NOUN
iajs-3524	14	24	for	for	ADP
iajs-3524	14	25	all	all	DET
iajs-3524	14	26	groups	group	NOUN
iajs-3524	14	27	.	.	PUNCT
iajs-3524	15	1	this	this	PRON
iajs-3524	15	2	suggests	suggest	VERB
iajs-3524	15	3	that	that	SCONJ
iajs-3524	15	4	the	the	DET
iajs-3524	15	5	best	good	ADJ
iajs-3524	15	6	medicine	medicine	NOUN
iajs-3524	15	7	and	and	CCONJ
iajs-3524	15	8	therapy	therapy	NOUN
iajs-3524	15	9	will	will	AUX
iajs-3524	15	10	be	be	AUX
iajs-3524	15	11	available	available	ADJ
iajs-3524	15	12	for	for	ADP
iajs-3524	15	13	these	these	DET
iajs-3524	15	14	patients	patient	NOUN
iajs-3524	15	15	.	.	PUNCT
iajs-3524	16	1	these	these	DET
iajs-3524	16	2	results	result	NOUN
iajs-3524	16	3	suggest	suggest	VERB
iajs-3524	16	4	that	that	SCONJ
iajs-3524	16	5	cl-3	cl-3	PRON
iajs-3524	16	6	might	might	AUX
iajs-3524	16	7	be	be	AUX
iajs-3524	16	8	a	a	DET
iajs-3524	16	9	biochemical	biochemical	ADJ
iajs-3524	16	10	diagnostic	diagnostic	NOUN
iajs-3524	16	11	for	for	ADP
iajs-3524	16	12	ra	ra	PROPN
iajs-3524	16	13	patients	patient	NOUN
iajs-3524	16	14	'	'	PART
iajs-3524	16	15	early	early	ADJ
iajs-3524	16	16	diagnosis	diagnosis	NOUN
iajs-3524	16	17	of	of	ADP
iajs-3524	16	18	diabetes	diabetes	NOUN
iajs-3524	16	19	.	.	PUNCT
iajs-3524	17	1	keywords	keyword	NOUN
iajs-3524	17	2	:	:	PUNCT
iajs-3524	17	3	collagenase-3	collagenase-3	NUM
iajs-3524	17	4	,	,	PUNCT
iajs-3524	17	5	rheumatoid	rheumatoid	NOUN
iajs-3524	17	6	arthritis	arthritis	NOUN
iajs-3524	17	7	,	,	PUNCT
iajs-3524	17	8	rheumatoid	rheumatoid	NOUN
iajs-3524	17	9	factor	factor	NOUN
iajs-3524	17	10	,	,	PUNCT
iajs-3524	17	11	type	type	NOUN
iajs-3524	17	12	2	2	NUM
iajs-3524	17	13	diabetes	diabetes	NOUN
iajs-3524	17	14	mellitus	mellitus	NOUN
iajs-3524	17	15	.	.	PUNCT
iajs-3524	18	1	1	1	X
iajs-3524	18	2	.	.	X
iajs-3524	18	3	introduction	introduction	NOUN
iajs-3524	18	4	rheumatoid	rheumatoid	NOUN
iajs-3524	18	5	arthritis	arthritis	NOUN
iajs-3524	18	6	,	,	PUNCT
iajs-3524	18	7	often	often	ADV
iajs-3524	18	8	known	know	VERB
iajs-3524	18	9	as	as	ADP
iajs-3524	18	10	ra	ra	PROPN
iajs-3524	18	11	,	,	PUNCT
iajs-3524	18	12	has	have	AUX
iajs-3524	18	13	been	be	AUX
iajs-3524	18	14	connected	connect	VERB
iajs-3524	18	15	to	to	ADP
iajs-3524	18	16	abnormalities	abnormality	NOUN
iajs-3524	18	17	in	in	ADP
iajs-3524	18	18	glucose	glucose	NOUN
iajs-3524	18	19	metabolism	metabolism	NOUN
iajs-3524	18	20	,	,	PUNCT
iajs-3524	18	21	most	most	ADV
iajs-3524	18	22	notably	notably	ADV
iajs-3524	18	23	insulin	insulin	NOUN
iajs-3524	18	24	resistance	resistance	NOUN
iajs-3524	18	25	,	,	PUNCT
iajs-3524	18	26	which	which	PRON
iajs-3524	18	27	may	may	AUX
iajs-3524	18	28	lead	lead	VERB
iajs-3524	18	29	to	to	PART
iajs-3524	18	30	type	type	VERB
iajs-3524	18	31	2	2	NUM
iajs-3524	18	32	diabetes	diabetes	NOUN
iajs-3524	18	33	(	(	PUNCT
iajs-3524	18	34	t2	t2	NOUN
iajs-3524	18	35	dm	dm	PROPN
iajs-3524	18	36	)	)	PUNCT
iajs-3524	19	1	[	[	X
iajs-3524	19	2	1	1	NUM
iajs-3524	19	3	]	]	PUNCT
iajs-3524	19	4	.	.	PUNCT
iajs-3524	20	1	this	this	DET
iajs-3524	20	2	connection	connection	NOUN
iajs-3524	20	3	has	have	AUX
iajs-3524	20	4	been	be	AUX
iajs-3524	20	5	shown	show	VERB
iajs-3524	20	6	in	in	ADP
iajs-3524	20	7	a	a	DET
iajs-3524	20	8	few	few	ADJ
iajs-3524	20	9	different	different	ADJ
iajs-3524	20	10	cases	case	NOUN
iajs-3524	20	11	.	.	PUNCT
iajs-3524	21	1	the	the	DET
iajs-3524	21	2	research	research	NOUN
iajs-3524	21	3	found	find	VERB
iajs-3524	21	4	that	that	SCONJ
iajs-3524	21	5	patients	patient	NOUN
iajs-3524	21	6	with	with	ADP
iajs-3524	21	7	ra	ra	PROPN
iajs-3524	21	8	had	have	VERB
iajs-3524	21	9	a	a	DET
iajs-3524	21	10	greater	great	ADJ
iajs-3524	21	11	risk	risk	NOUN
iajs-3524	21	12	of	of	ADP
iajs-3524	21	13	acquiring	acquire	VERB
iajs-3524	21	14	diabetes	diabete	NOUN
iajs-3524	21	15	,	,	PUNCT
iajs-3524	21	16	but	but	CCONJ
iajs-3524	21	17	the	the	DET
iajs-3524	21	18	researchers	researcher	NOUN
iajs-3524	21	19	were	be	AUX
iajs-3524	21	20	unable	unable	ADJ
iajs-3524	21	21	to	to	PART
iajs-3524	21	22	determine	determine	VERB
iajs-3524	21	23	whether	whether	SCONJ
iajs-3524	21	24	or	or	CCONJ
iajs-3524	21	25	not	not	PART
iajs-3524	21	26	those	those	PRON
iajs-3524	21	27	who	who	PRON
iajs-3524	21	28	already	already	ADV
iajs-3524	21	29	had	have	VERB
iajs-3524	21	30	t2	t2	NOUN
iajs-3524	21	31	dm	dm	PROPN
iajs-3524	21	32	had	have	VERB
iajs-3524	21	33	an	an	DET
iajs-3524	21	34	increased	increase	VERB
iajs-3524	21	35	risk	risk	NOUN
iajs-3524	21	36	of	of	ADP
iajs-3524	21	37	developing	develop	VERB
iajs-3524	21	38	ra	ra	PROPN
iajs-3524	21	39	.	.	PUNCT
iajs-3524	22	1	one	one	NUM
iajs-3524	22	2	of	of	ADP
iajs-3524	22	3	the	the	DET
iajs-3524	22	4	purposes	purpose	NOUN
iajs-3524	22	5	of	of	ADP
iajs-3524	22	6	the	the	DET
iajs-3524	22	7	research	research	NOUN
iajs-3524	22	8	as	as	ADP
iajs-3524	22	9	a	a	DET
iajs-3524	22	10	result	result	NOUN
iajs-3524	22	11	is	be	AUX
iajs-3524	22	12	to	to	PART
iajs-3524	22	13	investigate	investigate	VERB
iajs-3524	22	14	the	the	DET
iajs-3524	22	15	possibility	possibility	NOUN
iajs-3524	22	16	of	of	ADP
iajs-3524	22	17	an	an	DET
iajs-3524	22	18	occurrence	occurrence	NOUN
iajs-3524	22	19	in	in	ADP
iajs-3524	22	20	patients	patient	NOUN
iajs-3524	22	21	who	who	PRON
iajs-3524	22	22	have	have	VERB
iajs-3524	22	23	t2	t2	NOUN
iajs-3524	22	24	dm	dm	NUM
iajs-3524	23	1	[	[	X
iajs-3524	23	2	2	2	NUM
iajs-3524	23	3	]	]	PUNCT
iajs-3524	23	4	.	.	PUNCT
iajs-3524	24	1	the	the	DET
iajs-3524	24	2	development	development	NOUN
iajs-3524	24	3	of	of	ADP
iajs-3524	24	4	tolerance	tolerance	NOUN
iajs-3524	24	5	to	to	ADP
iajs-3524	24	6	self	self	NOUN
iajs-3524	24	7	-	-	PUNCT
iajs-3524	24	8	antigens	antigen	NOUN
iajs-3524	24	9	is	be	AUX
iajs-3524	24	10	facilitated	facilitate	VERB
iajs-3524	24	11	by	by	ADP
iajs-3524	24	12	regulatory	regulatory	ADJ
iajs-3524	24	13	t	t	NOUN
iajs-3524	24	14	cells	cell	NOUN
iajs-3524	24	15	,	,	PUNCT
iajs-3524	24	16	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
iajs-3524	24	17	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
iajs-3524	24	18	https://orcid.org/0009-0006-6985-9392	https://orcid.org/0009-0006-6985-9392	PROPN
iajs-3524	24	19	mailto:nadia.abd.mltd2@hiue.edu.iq	mailto:nadia.abd.mltd2@hiue.edu.iq	PROPN
iajs-3524	24	20	https://orcid.org/0000-0002-2742-3068	https://orcid.org/0000-0002-2742-3068	PROPN
iajs-3524	24	21	mailto:zainab.m.m@ihcoedu.uobaghdad.edu.iq	mailto:zainab.m.m@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-3524	24	22	ihjpas	ihjpa	NOUN
iajs-3524	24	23	.	.	PUNCT
iajs-3524	25	1	2024	2024	NUM
iajs-3524	25	2	,	,	PUNCT
iajs-3524	25	3	37(4	37(4	NOUN
iajs-3524	25	4	)	)	PUNCT
iajs-3524	25	5	287	287	NUM
iajs-3524	25	6	while	while	SCONJ
iajs-3524	25	7	the	the	DET
iajs-3524	25	8	pro	pro	ADJ
iajs-3524	25	9	-	-	ADJ
iajs-3524	25	10	inflammatory	inflammatory	ADJ
iajs-3524	25	11	response	response	NOUN
iajs-3524	25	12	to	to	ADP
iajs-3524	25	13	infections	infection	NOUN
iajs-3524	25	14	is	be	AUX
iajs-3524	25	15	mediated	mediate	VERB
iajs-3524	25	16	by	by	ADP
iajs-3524	25	17	th17	th17	NOUN
iajs-3524	25	18	cells	cell	NOUN
iajs-3524	25	19	.	.	PUNCT
iajs-3524	26	1	the	the	DET
iajs-3524	26	2	balance	balance	NOUN
iajs-3524	26	3	between	between	ADP
iajs-3524	26	4	treg	treg	PROPN
iajs-3524	26	5	and	and	CCONJ
iajs-3524	26	6	th17	th17	PROPN
iajs-3524	26	7	cells	cell	NOUN
iajs-3524	26	8	is	be	AUX
iajs-3524	26	9	disrupted	disrupt	VERB
iajs-3524	26	10	in	in	ADP
iajs-3524	26	11	ra	ra	PROPN
iajs-3524	26	12	as	as	ADV
iajs-3524	26	13	well	well	ADV
iajs-3524	26	14	as	as	ADP
iajs-3524	26	15	other	other	ADJ
iajs-3524	26	16	inflammatory	inflammatory	ADJ
iajs-3524	26	17	disorders	disorder	NOUN
iajs-3524	26	18	.	.	PUNCT
iajs-3524	27	1	because	because	SCONJ
iajs-3524	27	2	of	of	ADP
iajs-3524	27	3	a	a	DET
iajs-3524	27	4	rise	rise	NOUN
iajs-3524	27	5	in	in	ADP
iajs-3524	27	6	the	the	DET
iajs-3524	27	7	amount	amount	NOUN
iajs-3524	27	8	of	of	ADP
iajs-3524	27	9	glucose	glucose	NOUN
iajs-3524	27	10	that	that	PRON
iajs-3524	27	11	is	be	AUX
iajs-3524	27	12	consumed	consume	VERB
iajs-3524	27	13	and	and	CCONJ
iajs-3524	27	14	the	the	DET
iajs-3524	27	15	number	number	NOUN
iajs-3524	27	16	of	of	ADP
iajs-3524	27	17	glycolytic	glycolytic	ADJ
iajs-3524	27	18	pathways	pathway	NOUN
iajs-3524	27	19	,	,	PUNCT
iajs-3524	27	20	the	the	DET
iajs-3524	27	21	metabolic	metabolic	NOUN
iajs-3524	27	22	state	state	NOUN
iajs-3524	27	23	of	of	ADP
iajs-3524	27	24	ra	ra	PROPN
iajs-3524	27	25	undergoes	undergo	VERB
iajs-3524	27	26	a	a	DET
iajs-3524	27	27	transition	transition	NOUN
iajs-3524	27	28	from	from	ADP
iajs-3524	27	29	a	a	DET
iajs-3524	27	30	low	low	ADJ
iajs-3524	27	31	-	-	PUNCT
iajs-3524	27	32	energy	energy	NOUN
iajs-3524	27	33	state	state	NOUN
iajs-3524	27	34	to	to	ADP
iajs-3524	27	35	a	a	DET
iajs-3524	27	36	highenergy	highenergy	NOUN
iajs-3524	27	37	state	state	NOUN
iajs-3524	27	38	[	[	X
iajs-3524	27	39	3	3	NUM
iajs-3524	27	40	]	]	PUNCT
iajs-3524	27	41	.	.	PUNCT
iajs-3524	28	1	in	in	ADP
iajs-3524	28	2	human	human	ADJ
iajs-3524	28	3	beings	being	NOUN
iajs-3524	28	4	,	,	PUNCT
iajs-3524	28	5	the	the	DET
iajs-3524	28	6	matrix	matrix	NOUN
iajs-3524	28	7	metalloproteinase-13	metalloproteinase-13	PROPN
iajs-3524	28	8	(	(	PUNCT
iajs-3524	28	9	mmp-13	mmp-13	NOUN
iajs-3524	28	10	)	)	PUNCT
iajs-3524	28	11	gene	gene	NOUN
iajs-3524	28	12	[	[	X
iajs-3524	28	13	4	4	X
iajs-3524	28	14	]	]	PUNCT
iajs-3524	28	15	is	be	AUX
iajs-3524	28	16	responsible	responsible	ADJ
iajs-3524	28	17	for	for	ADP
iajs-3524	28	18	encoding	encode	VERB
iajs-3524	28	19	the	the	DET
iajs-3524	28	20	collagenase-3	collagenase-3	NUM
iajs-3524	28	21	(	(	PUNCT
iajs-3524	28	22	cl-3	cl-3	NOUN
iajs-3524	28	23	)	)	PUNCT
iajs-3524	28	24	enzyme	enzyme	NOUN
iajs-3524	28	25	.	.	PUNCT
iajs-3524	29	1	it	it	PRON
iajs-3524	29	2	is	be	AUX
iajs-3524	29	3	a	a	DET
iajs-3524	29	4	member	member	NOUN
iajs-3524	29	5	of	of	ADP
iajs-3524	29	6	the	the	DET
iajs-3524	29	7	mmp	mmp	PROPN
iajs-3524	29	8	family	family	NOUN
iajs-3524	29	9	,	,	PUNCT
iajs-3524	29	10	which	which	PRON
iajs-3524	29	11	stands	stand	VERB
iajs-3524	29	12	for	for	ADP
iajs-3524	29	13	matrix	matrix	NOUN
iajs-3524	29	14	metalloproteinases	metalloproteinase	NOUN
iajs-3524	29	15	[	[	X
iajs-3524	29	16	5	5	NUM
iajs-3524	29	17	]	]	PUNCT
iajs-3524	29	18	.	.	PUNCT
iajs-3524	30	1	the	the	DET
iajs-3524	30	2	mmp-13	mmp-13	PROPN
iajs-3524	30	3	has	have	VERB
iajs-3524	30	4	a	a	DET
iajs-3524	30	5	molecular	molecular	ADJ
iajs-3524	30	6	weight	weight	NOUN
iajs-3524	30	7	of	of	ADP
iajs-3524	30	8	54	54	NUM
iajs-3524	30	9	kda	kda	NOUN
iajs-3524	30	10	,	,	PUNCT
iajs-3524	30	11	according	accord	VERB
iajs-3524	30	12	to	to	ADP
iajs-3524	30	13	the	the	DET
iajs-3524	30	14	calculations	calculation	NOUN
iajs-3524	30	15	[	[	X
iajs-3524	30	16	6	6	NUM
iajs-3524	30	17	]	]	PUNCT
iajs-3524	30	18	.	.	PUNCT
iajs-3524	31	1	while	while	SCONJ
iajs-3524	31	2	the	the	DET
iajs-3524	31	3	catalytic	catalytic	ADJ
iajs-3524	31	4	domain	domain	NOUN
iajs-3524	31	5	of	of	ADP
iajs-3524	31	6	cl-3	cl-3	NOUN
iajs-3524	31	7	is	be	AUX
iajs-3524	31	8	ineffectual	ineffectual	ADJ
iajs-3524	31	9	on	on	ADP
iajs-3524	31	10	its	its	PRON
iajs-3524	31	11	own	own	ADJ
iajs-3524	31	12	,	,	PUNCT
iajs-3524	31	13	the	the	DET
iajs-3524	31	14	hemopexin	hemopexin	NOUN
iajs-3524	31	15	domain	domain	NOUN
iajs-3524	31	16	of	of	ADP
iajs-3524	31	17	cl-3	cl-3	X
iajs-3524	31	18	is	be	AUX
iajs-3524	31	19	involved	involve	VERB
iajs-3524	31	20	in	in	ADP
iajs-3524	31	21	the	the	DET
iajs-3524	31	22	degradation	degradation	NOUN
iajs-3524	31	23	of	of	ADP
iajs-3524	31	24	collagen	collagen	NOUN
iajs-3524	31	25	.	.	PUNCT
iajs-3524	32	1	is	be	AUX
iajs-3524	32	2	expressed	express	VERB
iajs-3524	32	3	in	in	ADP
iajs-3524	32	4	the	the	DET
iajs-3524	32	5	skeleton	skeleton	NOUN
iajs-3524	32	6	during	during	ADP
iajs-3524	32	7	the	the	DET
iajs-3524	32	8	whole	whole	NOUN
iajs-3524	32	9	of	of	ADP
iajs-3524	32	10	embryonic	embryonic	ADJ
iajs-3524	32	11	development	development	NOUN
iajs-3524	32	12	because	because	SCONJ
iajs-3524	32	13	it	it	PRON
iajs-3524	32	14	serves	serve	VERB
iajs-3524	32	15	as	as	ADP
iajs-3524	32	16	a	a	DET
iajs-3524	32	17	prerequisite	prerequisite	NOUN
iajs-3524	32	18	for	for	ADP
iajs-3524	32	19	the	the	DET
iajs-3524	32	20	reorganization	reorganization	NOUN
iajs-3524	32	21	of	of	ADP
iajs-3524	32	22	the	the	DET
iajs-3524	32	23	collagen	collagen	NOUN
iajs-3524	32	24	matrix	matrix	NOUN
iajs-3524	32	25	,	,	PUNCT
iajs-3524	32	26	which	which	PRON
iajs-3524	32	27	is	be	AUX
iajs-3524	32	28	essential	essential	ADJ
iajs-3524	32	29	to	to	PART
iajs-3524	32	30	stimulate	stimulate	VERB
iajs-3524	32	31	bone	bone	NOUN
iajs-3524	32	32	mineralization	mineralization	NOUN
iajs-3524	32	33	.	.	PUNCT
iajs-3524	33	1	pathological	pathological	ADJ
iajs-3524	33	2	diseases	disease	NOUN
iajs-3524	33	3	,	,	PUNCT
iajs-3524	33	4	such	such	ADJ
iajs-3524	33	5	as	as	ADP
iajs-3524	33	6	human	human	ADJ
iajs-3524	33	7	carcinomas	carcinoma	NOUN
iajs-3524	33	8	,	,	PUNCT
iajs-3524	33	9	ra	ra	PROPN
iajs-3524	33	10	,	,	PUNCT
iajs-3524	33	11	and	and	CCONJ
iajs-3524	33	12	osteoarthritis	osteoarthritis	NOUN
iajs-3524	33	13	(	(	PUNCT
iajs-3524	33	14	oa	oa	NOUN
iajs-3524	33	15	)	)	PUNCT
iajs-3524	33	16	,	,	PUNCT
iajs-3524	33	17	are	be	AUX
iajs-3524	33	18	examples	example	NOUN
iajs-3524	33	19	of	of	ADP
iajs-3524	33	20	those	those	PRON
iajs-3524	33	21	in	in	ADP
iajs-3524	33	22	which	which	PRON
iajs-3524	33	23	it	it	PRON
iajs-3524	33	24	is	be	AUX
iajs-3524	33	25	significantly	significantly	ADV
iajs-3524	33	26	overexpressed	overexpresse	VERB
iajs-3524	33	27	[	[	PUNCT
iajs-3524	33	28	7,8	7,8	NUM
iajs-3524	33	29	]	]	PUNCT
iajs-3524	33	30	.	.	PUNCT
iajs-3524	34	1	it	it	PRON
iajs-3524	34	2	is	be	AUX
iajs-3524	34	3	hypothesized	hypothesize	VERB
iajs-3524	34	4	that	that	SCONJ
iajs-3524	34	5	the	the	DET
iajs-3524	34	6	collagenase	collagenase	NOUN
iajs-3524	34	7	subfamily	subfamily	ADV
iajs-3524	34	8	of	of	ADP
iajs-3524	34	9	mmp	mmp	PROPN
iajs-3524	34	10	plays	play	VERB
iajs-3524	34	11	a	a	DET
iajs-3524	34	12	part	part	NOUN
iajs-3524	34	13	in	in	ADP
iajs-3524	34	14	the	the	DET
iajs-3524	34	15	articular	articular	ADJ
iajs-3524	34	16	cartilage	cartilage	NOUN
iajs-3524	34	17	degradation	degradation	NOUN
iajs-3524	34	18	that	that	PRON
iajs-3524	34	19	is	be	AUX
iajs-3524	34	20	characteristic	characteristic	ADJ
iajs-3524	34	21	of	of	ADP
iajs-3524	34	22	ra	ra	PROPN
iajs-3524	34	23	.	.	PUNCT
iajs-3524	35	1	since	since	SCONJ
iajs-3524	35	2	cl-3	cl-3	PRON
iajs-3524	35	3	has	have	VERB
iajs-3524	35	4	a	a	DET
iajs-3524	35	5	preference	preference	NOUN
iajs-3524	35	6	for	for	ADP
iajs-3524	35	7	collagen	collagen	NOUN
iajs-3524	35	8	type	type	PROPN
iajs-3524	35	9	ii	ii	PROPN
iajs-3524	35	10	,	,	PUNCT
iajs-3524	35	11	it	it	PRON
iajs-3524	35	12	is	be	AUX
iajs-3524	35	13	a	a	DET
iajs-3524	35	14	feasible	feasible	ADJ
iajs-3524	35	15	candidate	candidate	NOUN
iajs-3524	35	16	in	in	ADP
iajs-3524	35	17	the	the	DET
iajs-3524	35	18	process	process	NOUN
iajs-3524	35	19	of	of	ADP
iajs-3524	35	20	articular	articular	ADJ
iajs-3524	35	21	cartilage	cartilage	NOUN
iajs-3524	35	22	turnover	turnover	NOUN
iajs-3524	35	23	and	and	CCONJ
iajs-3524	35	24	a	a	DET
iajs-3524	35	25	prospective	prospective	ADJ
iajs-3524	35	26	therapeutic	therapeutic	ADJ
iajs-3524	35	27	target	target	NOUN
iajs-3524	35	28	[	[	X
iajs-3524	35	29	9,10	9,10	NUM
iajs-3524	35	30	]	]	SYM
iajs-3524	35	31	.	.	PUNCT
iajs-3524	36	1	2	2	X
iajs-3524	36	2	.	.	X
iajs-3524	36	3	materials	material	NOUN
iajs-3524	36	4	and	and	CCONJ
iajs-3524	36	5	methods	method	NOUN
iajs-3524	36	6	everyone	everyone	PRON
iajs-3524	36	7	who	who	PRON
iajs-3524	36	8	took	take	VERB
iajs-3524	36	9	part	part	NOUN
iajs-3524	36	10	in	in	ADP
iajs-3524	36	11	this	this	DET
iajs-3524	36	12	study	study	NOUN
iajs-3524	36	13	was	be	AUX
iajs-3524	36	14	between	between	ADP
iajs-3524	36	15	the	the	DET
iajs-3524	36	16	ages	age	NOUN
iajs-3524	36	17	of	of	ADP
iajs-3524	36	18	30	30	NUM
iajs-3524	36	19	and	and	CCONJ
iajs-3524	36	20	50	50	NUM
iajs-3524	36	21	,	,	PUNCT
iajs-3524	36	22	and	and	CCONJ
iajs-3524	36	23	they	they	PRON
iajs-3524	36	24	were	be	AUX
iajs-3524	36	25	randomly	randomly	ADV
iajs-3524	36	26	assigned	assign	VERB
iajs-3524	36	27	to	to	ADP
iajs-3524	36	28	one	one	NUM
iajs-3524	36	29	of	of	ADP
iajs-3524	36	30	three	three	NUM
iajs-3524	36	31	groups	group	NOUN
iajs-3524	36	32	:	:	PUNCT
iajs-3524	36	33	(	(	PUNCT
iajs-3524	36	34	g1	g1	PROPN
iajs-3524	36	35	)	)	PUNCT
iajs-3524	36	36	control	control	NOUN
iajs-3524	36	37	(	(	PUNCT
iajs-3524	36	38	n=50	n=50	PROPN
iajs-3524	36	39	)	)	PUNCT
iajs-3524	36	40	,	,	PUNCT
iajs-3524	36	41	(	(	PUNCT
iajs-3524	36	42	g2	g2	PROPN
iajs-3524	36	43	)	)	PUNCT
iajs-3524	36	44	ra	ra	PROPN
iajs-3524	36	45	(	(	PUNCT
iajs-3524	36	46	n=50	n=50	PROPN
iajs-3524	36	47	)	)	PUNCT
iajs-3524	36	48	,	,	PUNCT
iajs-3524	36	49	or	or	CCONJ
iajs-3524	36	50	(	(	PUNCT
iajs-3524	36	51	g3	g3	PROPN
iajs-3524	36	52	)	)	PUNCT
iajs-3524	36	53	ra	ra	PROPN
iajs-3524	36	54	with	with	ADP
iajs-3524	36	55	t2	t2	PROPN
iajs-3524	36	56	dm	dm	X
iajs-3524	36	57	(	(	PUNCT
iajs-3524	36	58	n=50	n=50	PROPN
iajs-3524	36	59	)	)	PUNCT
iajs-3524	36	60	.	.	PUNCT
iajs-3524	37	1	there	there	PRON
iajs-3524	37	2	are	be	VERB
iajs-3524	37	3	a	a	DET
iajs-3524	37	4	total	total	NOUN
iajs-3524	37	5	of	of	ADP
iajs-3524	37	6	150	150	NUM
iajs-3524	37	7	people	people	NOUN
iajs-3524	37	8	taking	take	VERB
iajs-3524	37	9	part	part	NOUN
iajs-3524	37	10	in	in	ADP
iajs-3524	37	11	this	this	DET
iajs-3524	37	12	study	study	NOUN
iajs-3524	37	13	.	.	PUNCT
iajs-3524	38	1	rheumatologists	rheumatologist	NOUN
iajs-3524	38	2	who	who	PRON
iajs-3524	38	3	have	have	AUX
iajs-3524	38	4	recently	recently	ADV
iajs-3524	38	5	diagnosed	diagnose	VERB
iajs-3524	38	6	(	(	PUNCT
iajs-3524	38	7	before	before	ADP
iajs-3524	38	8	to	to	ADP
iajs-3524	38	9	patients	patient	NOUN
iajs-3524	38	10	commencing	commence	VERB
iajs-3524	38	11	treatment	treatment	NOUN
iajs-3524	38	12	)	)	PUNCT
iajs-3524	38	13	patients	patient	NOUN
iajs-3524	38	14	at	at	ADP
iajs-3524	38	15	the	the	DET
iajs-3524	38	16	teaching	teaching	NOUN
iajs-3524	38	17	hospitals	hospital	NOUN
iajs-3524	38	18	located	locate	VERB
iajs-3524	38	19	in	in	ADP
iajs-3524	38	20	al	al	PROPN
iajs-3524	38	21	-	-	PUNCT
iajs-3524	38	22	yarmuk	yarmuk	PROPN
iajs-3524	38	23	and	and	CCONJ
iajs-3524	38	24	baghdad	baghdad	PROPN
iajs-3524	38	25	during	during	ADP
iajs-3524	38	26	october	october	PROPN
iajs-3524	38	27	2022	2022	NUM
iajs-3524	38	28	and	and	CCONJ
iajs-3524	38	29	january	january	PROPN
iajs-3524	38	30	2022	2022	NUM
iajs-3524	38	31	.	.	PUNCT
iajs-3524	39	1	the	the	DET
iajs-3524	39	2	person	person	NOUN
iajs-3524	39	3	interviews	interview	VERB
iajs-3524	39	4	with	with	ADP
iajs-3524	39	5	each	each	DET
iajs-3524	39	6	patient	patient	NOUN
iajs-3524	39	7	were	be	AUX
iajs-3524	39	8	carried	carry	VERB
iajs-3524	39	9	out	out	ADP
iajs-3524	39	10	using	use	VERB
iajs-3524	39	11	a	a	DET
iajs-3524	39	12	recently	recently	ADV
iajs-3524	39	13	developed	develop	VERB
iajs-3524	39	14	questionnaire	questionnaire	NOUN
iajs-3524	39	15	format	format	NOUN
iajs-3524	39	16	that	that	PRON
iajs-3524	39	17	contained	contain	VERB
iajs-3524	39	18	a	a	DET
iajs-3524	39	19	detailed	detailed	ADJ
iajs-3524	39	20	account	account	NOUN
iajs-3524	39	21	of	of	ADP
iajs-3524	39	22	the	the	DET
iajs-3524	39	23	medical	medical	ADJ
iajs-3524	39	24	history	history	NOUN
iajs-3524	39	25	of	of	ADP
iajs-3524	39	26	each	each	DET
iajs-3524	39	27	patient	patient	NOUN
iajs-3524	39	28	.	.	PUNCT
iajs-3524	40	1	the	the	DET
iajs-3524	40	2	interviews	interview	NOUN
iajs-3524	40	3	were	be	AUX
iajs-3524	40	4	conducted	conduct	VERB
iajs-3524	40	5	in	in	ADP
iajs-3524	40	6	this	this	DET
iajs-3524	40	7	manner	manner	NOUN
iajs-3524	40	8	all	all	DET
iajs-3524	40	9	the	the	DET
iajs-3524	40	10	way	way	NOUN
iajs-3524	40	11	through	through	ADV
iajs-3524	40	12	.	.	PUNCT
iajs-3524	41	1	the	the	DET
iajs-3524	41	2	tests	test	NOUN
iajs-3524	41	3	that	that	PRON
iajs-3524	41	4	were	be	AUX
iajs-3524	41	5	varied	varied	ADJ
iajs-3524	41	6	out	out	ADP
iajs-3524	41	7	of	of	ADP
iajs-3524	41	8	the	the	DET
iajs-3524	41	9	biochemical	biochemical	ADJ
iajs-3524	41	10	examinations	examination	NOUN
iajs-3524	41	11	were	be	AUX
iajs-3524	41	12	rheumatoid	rheumatoid	NOUN
iajs-3524	41	13	factor	factor	NOUN
iajs-3524	41	14	(	(	PUNCT
iajs-3524	41	15	rf	rf	NOUN
iajs-3524	41	16	)	)	PUNCT
iajs-3524	41	17	,	,	PUNCT
iajs-3524	41	18	anti	anti	ADJ
iajs-3524	41	19	-	-	ADJ
iajs-3524	41	20	cyclic	cyclic	ADJ
iajs-3524	41	21	citrullinated	citrullinate	VERB
iajs-3524	41	22	peptide	peptide	NOUN
iajs-3524	41	23	(	(	PUNCT
iajs-3524	41	24	anti	anti	ADJ
iajs-3524	41	25	-	-	ADJ
iajs-3524	41	26	ccp	ccp	X
iajs-3524	41	27	)	)	PUNCT
iajs-3524	41	28	,	,	PUNCT
iajs-3524	41	29	and	and	CCONJ
iajs-3524	41	30	cl-3	cl-3	X
iajs-3524	41	31	where	where	SCONJ
iajs-3524	41	32	a	a	DET
iajs-3524	41	33	sample	sample	NOUN
iajs-3524	41	34	of	of	ADP
iajs-3524	41	35	serum	serum	NOUN
iajs-3524	41	36	was	be	AUX
iajs-3524	41	37	used	use	VERB
iajs-3524	41	38	.	.	PUNCT
iajs-3524	42	1	also	also	ADV
iajs-3524	42	2	the	the	DET
iajs-3524	42	3	test	test	NOUN
iajs-3524	42	4	erythrocyte	erythrocyte	PROPN
iajs-3524	42	5	sedimentation	sedimentation	NOUN
iajs-3524	42	6	rate	rate	NOUN
iajs-3524	42	7	(	(	PUNCT
iajs-3524	42	8	esr	esr	PROPN
iajs-3524	42	9	)	)	PUNCT
iajs-3524	42	10	and	and	CCONJ
iajs-3524	42	11	glycated	glycate	VERB
iajs-3524	42	12	hemoglobin	hemoglobin	NOUN
iajs-3524	42	13	(	(	PUNCT
iajs-3524	42	14	hba1c	hba1c	PROPN
iajs-3524	42	15	)	)	PUNCT
iajs-3524	42	16	that	that	SCONJ
iajs-3524	42	17	a	a	DET
iajs-3524	42	18	sample	sample	NOUN
iajs-3524	42	19	of	of	ADP
iajs-3524	42	20	whole	whole	ADJ
iajs-3524	42	21	blood	blood	NOUN
iajs-3524	42	22	was	be	AUX
iajs-3524	42	23	used	use	VERB
iajs-3524	42	24	to	to	PART
iajs-3524	42	25	get	get	VERB
iajs-3524	42	26	an	an	DET
iajs-3524	42	27	accurate	accurate	ADJ
iajs-3524	42	28	reading	reading	NOUN
iajs-3524	42	29	.	.	PUNCT
iajs-3524	43	1	to	to	PART
iajs-3524	43	2	analyze	analyze	VERB
iajs-3524	43	3	the	the	DET
iajs-3524	43	4	data	datum	NOUN
iajs-3524	43	5	,	,	PUNCT
iajs-3524	43	6	the	the	DET
iajs-3524	43	7	statistical	statistical	ADJ
iajs-3524	43	8	program	program	NOUN
iajs-3524	43	9	known	know	VERB
iajs-3524	43	10	as	as	ADP
iajs-3524	43	11	statistical	statistical	ADJ
iajs-3524	43	12	packages	package	NOUN
iajs-3524	43	13	for	for	ADP
iajs-3524	43	14	social	social	ADJ
iajs-3524	43	15	sciencesversion	sciencesversion	NOUN
iajs-3524	43	16	21	21	NUM
iajs-3524	43	17	was	be	AUX
iajs-3524	43	18	used	use	VERB
iajs-3524	43	19	.	.	PUNCT
iajs-3524	44	1	the	the	DET
iajs-3524	44	2	mean	mean	ADJ
iajs-3524	44	3	value	value	NOUN
iajs-3524	44	4	as	as	ADV
iajs-3524	44	5	well	well	ADV
iajs-3524	44	6	as	as	ADP
iajs-3524	44	7	the	the	DET
iajs-3524	44	8	standard	standard	ADJ
iajs-3524	44	9	deviation	deviation	NOUN
iajs-3524	44	10	were	be	AUX
iajs-3524	44	11	utilized	utilize	VERB
iajs-3524	44	12	to	to	PART
iajs-3524	44	13	present	present	VERB
iajs-3524	44	14	a	a	DET
iajs-3524	44	15	condensed	condense	VERB
iajs-3524	44	16	overview	overview	NOUN
iajs-3524	44	17	of	of	ADP
iajs-3524	44	18	the	the	DET
iajs-3524	44	19	data	datum	NOUN
iajs-3524	44	20	.	.	PUNCT
iajs-3524	45	1	the	the	DET
iajs-3524	45	2	student	student	NOUN
iajs-3524	45	3	's	's	PART
iajs-3524	45	4	t	t	NOUN
iajs-3524	45	5	-	-	PUNCT
iajs-3524	45	6	test	test	NOUN
iajs-3524	45	7	,	,	PUNCT
iajs-3524	45	8	which	which	PRON
iajs-3524	45	9	is	be	AUX
iajs-3524	45	10	used	use	VERB
iajs-3524	45	11	to	to	PART
iajs-3524	45	12	determine	determine	VERB
iajs-3524	45	13	the	the	DET
iajs-3524	45	14	degree	degree	NOUN
iajs-3524	45	15	of	of	ADP
iajs-3524	45	16	separation	separation	NOUN
iajs-3524	45	17	between	between	ADP
iajs-3524	45	18	two	two	NUM
iajs-3524	45	19	independent	independent	ADJ
iajs-3524	45	20	means	mean	NOUN
iajs-3524	45	21	,	,	PUNCT
iajs-3524	45	22	was	be	AUX
iajs-3524	45	23	used	use	VERB
iajs-3524	45	24	to	to	PART
iajs-3524	45	25	explore	explore	VERB
iajs-3524	45	26	the	the	DET
iajs-3524	45	27	significance	significance	NOUN
iajs-3524	45	28	of	of	ADP
iajs-3524	45	29	the	the	DET
iajs-3524	45	30	difference	difference	NOUN
iajs-3524	45	31	in	in	ADP
iajs-3524	45	32	mean	mean	NOUN
iajs-3524	45	33	between	between	ADP
iajs-3524	45	34	a	a	DET
iajs-3524	45	35	variety	variety	NOUN
iajs-3524	45	36	of	of	ADP
iajs-3524	45	37	"	"	PUNCT
iajs-3524	45	38	quantitative	quantitative	ADJ
iajs-3524	45	39	data	datum	NOUN
iajs-3524	45	40	"	"	PUNCT
iajs-3524	45	41	kinds	kind	NOUN
iajs-3524	45	42	.	.	PUNCT
iajs-3524	46	1	in	in	ADP
iajs-3524	46	2	cases	case	NOUN
iajs-3524	46	3	where	where	SCONJ
iajs-3524	46	4	the	the	DET
iajs-3524	46	5	p	p	NOUN
iajs-3524	46	6	-	-	PUNCT
iajs-3524	46	7	value	value	NOUN
iajs-3524	46	8	was	be	AUX
iajs-3524	46	9	less	less	ADJ
iajs-3524	46	10	than	than	ADP
iajs-3524	46	11	0.05	0.05	NUM
iajs-3524	46	12	or	or	CCONJ
iajs-3524	46	13	was	be	AUX
iajs-3524	46	14	otherwise	otherwise	ADV
iajs-3524	46	15	comparable	comparable	ADJ
iajs-3524	46	16	to	to	ADP
iajs-3524	46	17	that	that	DET
iajs-3524	46	18	value	value	NOUN
iajs-3524	46	19	,	,	PUNCT
iajs-3524	46	20	it	it	PRON
iajs-3524	46	21	was	be	AUX
iajs-3524	46	22	decided	decide	VERB
iajs-3524	46	23	that	that	SCONJ
iajs-3524	46	24	statistical	statistical	ADJ
iajs-3524	46	25	significance	significance	NOUN
iajs-3524	46	26	existed	exist	VERB
iajs-3524	46	27	.	.	PUNCT
iajs-3524	47	1	highly	highly	ADV
iajs-3524	47	2	significant	significant	ADJ
iajs-3524	47	3	(	(	PUNCT
iajs-3524	47	4	hs	hs	X
iajs-3524	47	5	)	)	PUNCT
iajs-3524	47	6	expressed	express	VERB
iajs-3524	47	7	at	at	ADP
iajs-3524	47	8	p	p	NOUN
iajs-3524	47	9	≤	≤	NUM
iajs-3524	47	10	0.01	0.01	NUM
iajs-3524	47	11	.	.	PUNCT
iajs-3524	48	1	3	3	X
iajs-3524	48	2	.	.	NOUN
iajs-3524	48	3	results	result	NOUN
iajs-3524	48	4	and	and	CCONJ
iajs-3524	48	5	discussion	discussion	NOUN
iajs-3524	48	6	rheumatoid	rheumatoid	VERB
iajs-3524	48	7	arthritis	arthritis	NOUN
iajs-3524	48	8	may	may	AUX
iajs-3524	48	9	be	be	AUX
iajs-3524	48	10	a	a	DET
iajs-3524	48	11	chronic	chronic	NOUN
iajs-3524	48	12	,	,	PUNCT
iajs-3524	48	13	multisystemic	multisystemic	ADJ
iajs-3524	48	14	,	,	PUNCT
iajs-3524	48	15	autoimmune	autoimmune	ADJ
iajs-3524	48	16	,	,	PUNCT
iajs-3524	48	17	and	and	CCONJ
iajs-3524	48	18	inflammatory	inflammatory	ADJ
iajs-3524	48	19	condition	condition	NOUN
iajs-3524	48	20	that	that	PRON
iajs-3524	48	21	can	can	AUX
iajs-3524	48	22	produce	produce	VERB
iajs-3524	48	23	substantial	substantial	ADJ
iajs-3524	48	24	functional	functional	ADJ
iajs-3524	48	25	impairment	impairment	NOUN
iajs-3524	48	26	and	and	CCONJ
iajs-3524	48	27	depressive	depressive	ADJ
iajs-3524	48	28	feelings	feeling	NOUN
iajs-3524	48	29	.	.	PUNCT
iajs-3524	49	1	the	the	DET
iajs-3524	49	2	performance	performance	NOUN
iajs-3524	49	3	of	of	ADP
iajs-3524	49	4	routine	routine	ADJ
iajs-3524	49	5	duties	duty	NOUN
iajs-3524	49	6	and	and	CCONJ
iajs-3524	49	7	activities	activity	NOUN
iajs-3524	49	8	at	at	ADP
iajs-3524	49	9	work	work	NOUN
iajs-3524	49	10	may	may	AUX
iajs-3524	49	11	be	be	AUX
iajs-3524	49	12	adversely	adversely	ADV
iajs-3524	49	13	affected	affect	VERB
iajs-3524	49	14	as	as	ADP
iajs-3524	49	15	a	a	DET
iajs-3524	49	16	result	result	NOUN
iajs-3524	49	17	of	of	ADP
iajs-3524	49	18	these	these	DET
iajs-3524	49	19	changes	change	NOUN
iajs-3524	49	20	,	,	PUNCT
iajs-3524	49	21	which	which	PRON
iajs-3524	49	22	may	may	AUX
iajs-3524	49	23	eventually	eventually	ADV
iajs-3524	49	24	influence	influence	VERB
iajs-3524	49	25	life	life	NOUN
iajs-3524	49	26	quality	quality	NOUN
iajs-3524	49	27	[	[	X
iajs-3524	49	28	11	11	NUM
iajs-3524	49	29	]	]	PUNCT
iajs-3524	49	30	.	.	PUNCT
iajs-3524	50	1	ihjpas	ihjpas	PROPN
iajs-3524	50	2	.	.	PUNCT
iajs-3524	51	1	2024	2024	NUM
iajs-3524	51	2	,	,	PUNCT
iajs-3524	51	3	37(4	37(4	X
iajs-3524	51	4	)	)	PUNCT
iajs-3524	51	5	288	288	NUM
iajs-3524	51	6	serum	serum	NOUN
iajs-3524	51	7	levels	level	NOUN
iajs-3524	51	8	of	of	ADP
iajs-3524	51	9	anti	anti	ADJ
iajs-3524	51	10	-	-	ADJ
iajs-3524	51	11	ccp	ccp	ADJ
iajs-3524	51	12	and	and	CCONJ
iajs-3524	51	13	cl-3	cl-3	PRON
iajs-3524	51	14	were	be	AUX
iajs-3524	51	15	tested	test	VERB
iajs-3524	51	16	in	in	ADP
iajs-3524	51	17	three	three	NUM
iajs-3524	51	18	groups	group	NOUN
iajs-3524	51	19	:	:	PUNCT
iajs-3524	51	20	g1	g1	NOUN
iajs-3524	51	21	represented	represent	VERB
iajs-3524	51	22	the	the	DET
iajs-3524	51	23	control	control	NOUN
iajs-3524	51	24	group	group	NOUN
iajs-3524	51	25	,	,	PUNCT
iajs-3524	51	26	g2	g2	PROPN
iajs-3524	51	27	represented	represent	VERB
iajs-3524	51	28	patients	patient	NOUN
iajs-3524	51	29	with	with	ADP
iajs-3524	51	30	ra	ra	PROPN
iajs-3524	51	31	,	,	PUNCT
iajs-3524	51	32	and	and	CCONJ
iajs-3524	51	33	g3	g3	PROPN
iajs-3524	51	34	represented	represent	VERB
iajs-3524	51	35	patients	patient	NOUN
iajs-3524	51	36	with	with	ADP
iajs-3524	51	37	ra	ra	PROPN
iajs-3524	51	38	who	who	PRON
iajs-3524	51	39	also	also	ADV
iajs-3524	51	40	had	have	VERB
iajs-3524	51	41	t2	t2	NOUN
iajs-3524	51	42	dm	dm	PROPN
iajs-3524	51	43	as	as	ADP
iajs-3524	51	44	a	a	DET
iajs-3524	51	45	consequence	consequence	NOUN
iajs-3524	51	46	.	.	PUNCT
iajs-3524	52	1	when	when	SCONJ
iajs-3524	52	2	compared	compare	VERB
iajs-3524	52	3	to	to	ADP
iajs-3524	52	4	group	group	NOUN
iajs-3524	52	5	(	(	PUNCT
iajs-3524	52	6	g1	g1	PROPN
iajs-3524	52	7	)	)	PUNCT
iajs-3524	52	8	,	,	PUNCT
iajs-3524	52	9	the	the	DET
iajs-3524	52	10	serum	serum	NOUN
iajs-3524	52	11	rf	rf	NOUN
iajs-3524	52	12	levels	level	NOUN
iajs-3524	52	13	in	in	ADP
iajs-3524	52	14	groups	group	NOUN
iajs-3524	52	15	(	(	PUNCT
iajs-3524	52	16	g2	g2	PROPN
iajs-3524	52	17	)	)	PUNCT
iajs-3524	52	18	and	and	CCONJ
iajs-3524	52	19	(	(	PUNCT
iajs-3524	52	20	g3	g3	NOUN
iajs-3524	52	21	)	)	PUNCT
iajs-3524	52	22	were	be	AUX
iajs-3524	52	23	significantly	significantly	ADV
iajs-3524	52	24	greater	great	ADJ
iajs-3524	52	25	than	than	ADP
iajs-3524	52	26	those	those	PRON
iajs-3524	52	27	seen	see	VERB
iajs-3524	52	28	in	in	ADP
iajs-3524	52	29	group	group	NOUN
iajs-3524	52	30	(	(	PUNCT
iajs-3524	52	31	g1	g1	PROPN
iajs-3524	52	32	)	)	PUNCT
iajs-3524	52	33	,	,	PUNCT
iajs-3524	52	34	as	as	SCONJ
iajs-3524	52	35	shown	show	VERB
iajs-3524	52	36	by	by	ADP
iajs-3524	52	37	the	the	DET
iajs-3524	52	38	data	datum	NOUN
iajs-3524	52	39	in	in	ADP
iajs-3524	52	40	table	table	NOUN
iajs-3524	52	41	1	1	NUM
iajs-3524	52	42	.	.	PUNCT
iajs-3524	53	1	in	in	ADP
iajs-3524	53	2	addition	addition	NOUN
iajs-3524	53	3	,	,	PUNCT
iajs-3524	53	4	a	a	DET
iajs-3524	53	5	statistically	statistically	ADV
iajs-3524	53	6	significant	significant	ADJ
iajs-3524	53	7	higher	high	ADJ
iajs-3524	53	8	quantity	quantity	NOUN
iajs-3524	53	9	was	be	AUX
iajs-3524	53	10	recorded	record	VERB
iajs-3524	53	11	in	in	ADP
iajs-3524	53	12	(	(	PUNCT
iajs-3524	53	13	g3	g3	NOUN
iajs-3524	53	14	)	)	PUNCT
iajs-3524	53	15	in	in	ADP
iajs-3524	53	16	comparison	comparison	NOUN
iajs-3524	53	17	to	to	ADP
iajs-3524	53	18	what	what	PRON
iajs-3524	53	19	was	be	AUX
iajs-3524	53	20	seen	see	VERB
iajs-3524	53	21	in	in	ADP
iajs-3524	53	22	(	(	PUNCT
iajs-3524	53	23	g2	g2	PROPN
iajs-3524	53	24	)	)	PUNCT
iajs-3524	53	25	.	.	PUNCT
iajs-3524	54	1	table	table	NOUN
iajs-3524	54	2	1	1	NUM
iajs-3524	54	3	.	.	PUNCT
iajs-3524	55	1	levels	level	NOUN
iajs-3524	55	2	of	of	ADP
iajs-3524	55	3	rf	rf	NOUN
iajs-3524	55	4	,	,	PUNCT
iajs-3524	55	5	esr	esr	NOUN
iajs-3524	55	6	,	,	PUNCT
iajs-3524	55	7	and	and	CCONJ
iajs-3524	55	8	hba1c	hba1c	PROPN
iajs-3524	55	9	in	in	ADP
iajs-3524	55	10	the	the	DET
iajs-3524	55	11	studied	study	VERB
iajs-3524	55	12	groups	group	NOUN
iajs-3524	55	13	.	.	PUNCT
iajs-3524	56	1	parameter	parameter	PROPN
iajs-3524	56	2	mean±	mean±	PROPN
iajs-3524	56	3	sd	sd	ADP
iajs-3524	56	4	p	p	NOUN
iajs-3524	56	5	-	-	PUNCT
iajs-3524	56	6	value	value	NOUN
iajs-3524	56	7	g1	g1	NOUN
iajs-3524	56	8	(	(	PUNCT
iajs-3524	56	9	n=50	n=50	ADJ
iajs-3524	56	10	)	)	PUNCT
iajs-3524	56	11	g2	g2	PROPN
iajs-3524	56	12	(	(	PUNCT
iajs-3524	56	13	n=50	n=50	PROPN
iajs-3524	56	14	)	)	PUNCT
iajs-3524	56	15	g3	g3	NOUN
iajs-3524	56	16	(	(	PUNCT
iajs-3524	56	17	n=50	n=50	ADJ
iajs-3524	56	18	)	)	PUNCT
iajs-3524	56	19	g1	g1	PROPN
iajs-3524	56	20	&	&	CCONJ
iajs-3524	56	21	g2	g2	PROPN
iajs-3524	56	22	g1	g1	PROPN
iajs-3524	56	23	&	&	CCONJ
iajs-3524	56	24	g3	g3	PROPN
iajs-3524	56	25	g2	g2	PROPN
iajs-3524	56	26	&	&	CCONJ
iajs-3524	56	27	g3	g3	PROPN
iajs-3524	56	28	rf	rf	ADJ
iajs-3524	56	29	(	(	PUNCT
iajs-3524	56	30	iu	iu	NOUN
iajs-3524	56	31	/	/	SYM
iajs-3524	56	32	ml	ml	VERB
iajs-3524	56	33	)	)	PUNCT
iajs-3524	56	34	0.95±0,60	0.95±0,60	NUM
iajs-3524	57	1	3.57±0,76	3.57±0,76	NUM
iajs-3524	58	1	3.69±0,73	3.69±0,73	NUM
iajs-3524	58	2	hs	hs	INTJ
iajs-3524	58	3	hs	hs	PROPN
iajs-3524	58	4	ns	ns	PROPN
iajs-3524	58	5	esr	esr	PROPN
iajs-3524	58	6	(	(	PUNCT
iajs-3524	58	7	mm	mm	PROPN
iajs-3524	58	8	/	/	SYM
iajs-3524	58	9	hr	hr	NOUN
iajs-3524	58	10	)	)	PUNCT
iajs-3524	58	11	12.33±4,21	12.33±4,21	PROPN
iajs-3524	58	12	34.37±8,36	34.37±8,36	NUM
iajs-3524	58	13	45.10±7,43	45.10±7,43	PROPN
iajs-3524	59	1	hs	hs	PROPN
iajs-3524	59	2	hs	hs	PROPN
iajs-3524	59	3	hs	hs	PROPN
iajs-3524	59	4	hba1c	hba1c	PROPN
iajs-3524	59	5	(	(	PUNCT
iajs-3524	59	6	%	%	INTJ
iajs-3524	59	7	)	)	PUNCT
iajs-3524	59	8	4.87±0.46	4.87±0.46	PROPN
iajs-3524	59	9	5.14±0.59	5.14±0.59	PROPN
iajs-3524	59	10	7.82±0.97	7.82±0.97	NOUN
iajs-3524	59	11	ns	ns	NUM
iajs-3524	59	12	hs	hs	PROPN
iajs-3524	59	13	hs	hs	PROPN
iajs-3524	59	14	*	*	PROPN
iajs-3524	59	15	*	*	PROPN
iajs-3524	59	16	hs	hs	ADJ
iajs-3524	59	17	:	:	PUNCT
iajs-3524	59	18	high	high	ADJ
iajs-3524	59	19	significantly	significantly	ADV
iajs-3524	59	20	at	at	ADP
iajs-3524	59	21	the	the	DET
iajs-3524	59	22	0.01	0.01	NUM
iajs-3524	59	23	level	level	NOUN
iajs-3524	59	24	.	.	PUNCT
iajs-3524	60	1	the	the	DET
iajs-3524	60	2	rf	rf	ADJ
iajs-3524	60	3	autoantibodies	autoantibody	NOUN
iajs-3524	60	4	are	be	AUX
iajs-3524	60	5	generated	generate	VERB
iajs-3524	60	6	locally	locally	ADV
iajs-3524	60	7	by	by	ADP
iajs-3524	60	8	b	b	PROPN
iajs-3524	60	9	cells	cell	NOUN
iajs-3524	60	10	in	in	ADP
iajs-3524	60	11	lymphoid	lymphoid	ADJ
iajs-3524	60	12	follicles	follicle	NOUN
iajs-3524	60	13	and	and	CCONJ
iajs-3524	60	14	germinal	germinal	ADJ
iajs-3524	60	15	center	center	NOUN
iajs-3524	60	16	-	-	PUNCT
iajs-3524	60	17	like	like	ADJ
iajs-3524	60	18	structures	structure	NOUN
iajs-3524	60	19	that	that	PRON
iajs-3524	60	20	arise	arise	VERB
iajs-3524	60	21	in	in	ADP
iajs-3524	60	22	inflamed	inflame	VERB
iajs-3524	60	23	ra	ra	PROPN
iajs-3524	60	24	synovial	synovial	ADJ
iajs-3524	60	25	.	.	PUNCT
iajs-3524	61	1	these	these	DET
iajs-3524	61	2	autoantibodies	autoantibody	NOUN
iajs-3524	61	3	directly	directly	ADV
iajs-3524	61	4	bind	bind	VERB
iajs-3524	61	5	to	to	ADP
iajs-3524	61	6	the	the	DET
iajs-3524	61	7	"	"	PUNCT
iajs-3524	61	8	fraction	fraction	NOUN
iajs-3524	61	9	crystallizable	crystallizable	ADJ
iajs-3524	61	10	"	"	PUNCT
iajs-3524	61	11	(	(	PUNCT
iajs-3524	61	12	fc	fc	INTJ
iajs-3524	61	13	)	)	PUNCT
iajs-3524	61	14	component	component	NOUN
iajs-3524	61	15	of	of	ADP
iajs-3524	61	16	accumulated	accumulate	VERB
iajs-3524	61	17	igg	igg	PROPN
iajs-3524	61	18	.	.	PUNCT
iajs-3524	62	1	studies	study	NOUN
iajs-3524	62	2	have	have	AUX
iajs-3524	62	3	shown	show	VERB
iajs-3524	62	4	that	that	SCONJ
iajs-3524	62	5	rf	rf	ADJ
iajs-3524	62	6	testing	testing	NOUN
iajs-3524	62	7	in	in	ADP
iajs-3524	62	8	individuals	individual	NOUN
iajs-3524	62	9	with	with	ADP
iajs-3524	62	10	ra	ra	PROPN
iajs-3524	62	11	has	have	VERB
iajs-3524	62	12	a	a	DET
iajs-3524	62	13	sensitivity	sensitivity	NOUN
iajs-3524	62	14	of	of	ADP
iajs-3524	62	15	up	up	ADP
iajs-3524	62	16	to	to	PART
iajs-3524	62	17	90	90	NUM
iajs-3524	62	18	%	%	NOUN
iajs-3524	62	19	and	and	CCONJ
iajs-3524	62	20	an	an	DET
iajs-3524	62	21	accuracy	accuracy	NOUN
iajs-3524	62	22	ranging	range	VERB
iajs-3524	62	23	from	from	ADP
iajs-3524	62	24	48	48	NUM
iajs-3524	62	25	to	to	PART
iajs-3524	62	26	92	92	NUM
iajs-3524	62	27	%	%	NOUN
iajs-3524	62	28	.	.	PUNCT
iajs-3524	63	1	according	accord	VERB
iajs-3524	63	2	to	to	ADP
iajs-3524	63	3	table	table	NOUN
iajs-3524	63	4	1	1	NUM
iajs-3524	63	5	,	,	PUNCT
iajs-3524	63	6	groups	group	NOUN
iajs-3524	63	7	(	(	PUNCT
iajs-3524	63	8	g2	g2	PROPN
iajs-3524	63	9	)	)	PUNCT
iajs-3524	63	10	and	and	CCONJ
iajs-3524	63	11	(	(	PUNCT
iajs-3524	63	12	g3	g3	NOUN
iajs-3524	63	13	)	)	PUNCT
iajs-3524	63	14	revealed	reveal	VERB
iajs-3524	63	15	a	a	DET
iajs-3524	63	16	significant	significant	ADJ
iajs-3524	63	17	increase	increase	NOUN
iajs-3524	63	18	in	in	ADP
iajs-3524	63	19	esr	esr	PROPN
iajs-3524	63	20	levels	level	NOUN
iajs-3524	63	21	compared	compare	VERB
iajs-3524	63	22	to	to	ADP
iajs-3524	63	23	group	group	NOUN
iajs-3524	63	24	(	(	PUNCT
iajs-3524	63	25	g1	g1	PROPN
iajs-3524	63	26	)	)	PUNCT
iajs-3524	63	27	.	.	PUNCT
iajs-3524	64	1	results	result	NOUN
iajs-3524	64	2	agree	agree	VERB
iajs-3524	64	3	with	with	ADP
iajs-3524	64	4	another	another	DET
iajs-3524	64	5	study	study	NOUN
iajs-3524	64	6	[	[	X
iajs-3524	64	7	12	12	NUM
iajs-3524	64	8	]	]	PUNCT
iajs-3524	64	9	.	.	PUNCT
iajs-3524	65	1	when	when	SCONJ
iajs-3524	65	2	examining	examine	VERB
iajs-3524	65	3	a	a	DET
iajs-3524	65	4	variety	variety	NOUN
iajs-3524	65	5	of	of	ADP
iajs-3524	65	6	clinical	clinical	ADJ
iajs-3524	65	7	diseases	disease	NOUN
iajs-3524	65	8	,	,	PUNCT
iajs-3524	65	9	including	include	VERB
iajs-3524	65	10	ra	ra	PROPN
iajs-3524	65	11	,	,	PUNCT
iajs-3524	65	12	an	an	DET
iajs-3524	65	13	elevated	elevated	ADJ
iajs-3524	65	14	esr	esr	PROPN
iajs-3524	65	15	might	might	AUX
iajs-3524	65	16	be	be	AUX
iajs-3524	65	17	of	of	ADP
iajs-3524	65	18	assistance	assistance	NOUN
iajs-3524	65	19	[	[	X
iajs-3524	65	20	13	13	NUM
iajs-3524	65	21	]	]	PUNCT
iajs-3524	65	22	.	.	PUNCT
iajs-3524	66	1	in	in	ADP
iajs-3524	66	2	ra	ra	PROPN
iajs-3524	66	3	patients	patient	NOUN
iajs-3524	66	4	,	,	PUNCT
iajs-3524	66	5	the	the	DET
iajs-3524	66	6	esr	esr	PROPN
iajs-3524	66	7	is	be	AUX
iajs-3524	66	8	often	often	ADV
iajs-3524	66	9	use	use	VERB
iajs-3524	66	10	as	as	ADP
iajs-3524	66	11	a	a	DET
iajs-3524	66	12	monitoring	monitoring	NOUN
iajs-3524	66	13	tool	tool	NOUN
iajs-3524	66	14	for	for	ADP
iajs-3524	66	15	inflammation	inflammation	NOUN
iajs-3524	66	16	even	even	ADV
iajs-3524	66	17	though	though	SCONJ
iajs-3524	66	18	it	it	PRON
iajs-3524	66	19	is	be	AUX
iajs-3524	66	20	not	not	PART
iajs-3524	66	21	a	a	DET
iajs-3524	66	22	diagnostic	diagnostic	ADJ
iajs-3524	66	23	tool	tool	NOUN
iajs-3524	66	24	for	for	ADP
iajs-3524	66	25	the	the	DET
iajs-3524	66	26	underlying	underlie	VERB
iajs-3524	66	27	cause	cause	NOUN
iajs-3524	66	28	of	of	ADP
iajs-3524	66	29	the	the	DET
iajs-3524	66	30	disease	disease	NOUN
iajs-3524	66	31	.	.	PUNCT
iajs-3524	67	1	it	it	PRON
iajs-3524	67	2	is	be	AUX
iajs-3524	67	3	the	the	DET
iajs-3524	67	4	result	result	NOUN
iajs-3524	67	5	of	of	ADP
iajs-3524	67	6	the	the	DET
iajs-3524	67	7	esr	esr	PROPN
iajs-3524	67	8	strategy	strategy	NOUN
iajs-3524	67	9	,	,	PUNCT
iajs-3524	67	10	which	which	PRON
iajs-3524	67	11	is	be	AUX
iajs-3524	67	12	uncomplicated	uncomplicated	ADJ
iajs-3524	67	13	,	,	PUNCT
iajs-3524	67	14	achievable	achievable	ADJ
iajs-3524	67	15	,	,	PUNCT
iajs-3524	67	16	applicable	applicable	ADJ
iajs-3524	67	17	,	,	PUNCT
iajs-3524	67	18	and	and	CCONJ
iajs-3524	67	19	inexpensive	inexpensive	ADJ
iajs-3524	67	20	in	in	ADP
iajs-3524	67	21	addition	addition	NOUN
iajs-3524	67	22	to	to	ADP
iajs-3524	67	23	having	have	VERB
iajs-3524	67	24	great	great	ADJ
iajs-3524	67	25	therapeutic	therapeutic	ADJ
iajs-3524	67	26	significance	significance	NOUN
iajs-3524	67	27	.	.	PUNCT
iajs-3524	68	1	an	an	DET
iajs-3524	68	2	elevated	elevated	ADJ
iajs-3524	68	3	esr	esr	PROPN
iajs-3524	68	4	may	may	AUX
iajs-3524	68	5	be	be	AUX
iajs-3524	68	6	a	a	DET
iajs-3524	68	7	result	result	NOUN
iajs-3524	68	8	of	of	ADP
iajs-3524	68	9	inflammatory	inflammatory	ADJ
iajs-3524	68	10	responses	response	NOUN
iajs-3524	68	11	or	or	CCONJ
iajs-3524	68	12	the	the	DET
iajs-3524	68	13	breakdown	breakdown	NOUN
iajs-3524	68	14	of	of	ADP
iajs-3524	68	15	tissue	tissue	NOUN
iajs-3524	68	16	in	in	ADP
iajs-3524	68	17	the	the	DET
iajs-3524	68	18	body	body	NOUN
iajs-3524	68	19	,	,	PUNCT
iajs-3524	68	20	described	describe	VERB
iajs-3524	68	21	in	in	ADP
iajs-3524	68	22	previous	previous	ADJ
iajs-3524	68	23	study	study	NOUN
iajs-3524	68	24	[	[	X
iajs-3524	68	25	14	14	NUM
iajs-3524	68	26	]	]	PUNCT
iajs-3524	68	27	.	.	PUNCT
iajs-3524	69	1	the	the	DET
iajs-3524	69	2	levels	level	NOUN
iajs-3524	69	3	of	of	ADP
iajs-3524	69	4	hba1c	hba1c	PROPN
iajs-3524	69	5	were	be	AUX
iajs-3524	69	6	also	also	ADV
iajs-3524	69	7	established	establish	VERB
iajs-3524	69	8	as	as	ADP
iajs-3524	69	9	a	a	DET
iajs-3524	69	10	part	part	NOUN
iajs-3524	69	11	of	of	ADP
iajs-3524	69	12	this	this	DET
iajs-3524	69	13	inquiry	inquiry	NOUN
iajs-3524	69	14	that	that	PRON
iajs-3524	69	15	was	be	AUX
iajs-3524	69	16	carried	carry	VERB
iajs-3524	69	17	out	out	ADP
iajs-3524	69	18	.	.	PUNCT
iajs-3524	70	1	the	the	DET
iajs-3524	70	2	results	result	NOUN
iajs-3524	70	3	of	of	ADP
iajs-3524	70	4	the	the	DET
iajs-3524	70	5	hba1c	hba1c	PROPN
iajs-3524	70	6	test	test	NOUN
iajs-3524	70	7	showed	show	VERB
iajs-3524	70	8	that	that	SCONJ
iajs-3524	70	9	the	the	DET
iajs-3524	70	10	rise	rise	NOUN
iajs-3524	70	11	in	in	ADP
iajs-3524	70	12	(	(	PUNCT
iajs-3524	70	13	g2	g2	PROPN
iajs-3524	70	14	)	)	PUNCT
iajs-3524	70	15	was	be	AUX
iajs-3524	70	16	not	not	PART
iajs-3524	70	17	statistically	statistically	ADV
iajs-3524	70	18	significant	significant	ADJ
iajs-3524	70	19	when	when	SCONJ
iajs-3524	70	20	compared	compare	VERB
iajs-3524	70	21	to	to	ADP
iajs-3524	70	22	the	the	DET
iajs-3524	70	23	increase	increase	NOUN
iajs-3524	70	24	in	in	ADP
iajs-3524	70	25	(	(	PUNCT
iajs-3524	70	26	g1	g1	PROPN
iajs-3524	70	27	)	)	PUNCT
iajs-3524	70	28	,	,	PUNCT
iajs-3524	70	29	but	but	CCONJ
iajs-3524	70	30	the	the	DET
iajs-3524	70	31	increase	increase	NOUN
iajs-3524	70	32	in	in	ADP
iajs-3524	70	33	(	(	PUNCT
iajs-3524	70	34	g3	g3	NOUN
iajs-3524	70	35	)	)	PUNCT
iajs-3524	70	36	was	be	AUX
iajs-3524	70	37	statistically	statistically	ADV
iajs-3524	70	38	significant	significant	ADJ
iajs-3524	70	39	when	when	SCONJ
iajs-3524	70	40	compared	compare	VERB
iajs-3524	70	41	to	to	ADP
iajs-3524	70	42	both	both	PRON
iajs-3524	70	43	(	(	PUNCT
iajs-3524	70	44	g2	g2	PROPN
iajs-3524	70	45	)	)	PUNCT
iajs-3524	70	46	and	and	CCONJ
iajs-3524	70	47	(	(	PUNCT
iajs-3524	70	48	g1	g1	PROPN
iajs-3524	70	49	)	)	PUNCT
iajs-3524	70	50	.	.	PUNCT
iajs-3524	71	1	the	the	DET
iajs-3524	71	2	results	result	NOUN
iajs-3524	71	3	of	of	ADP
iajs-3524	71	4	the	the	DET
iajs-3524	71	5	vast	vast	ADJ
iajs-3524	71	6	majority	majority	NOUN
iajs-3524	71	7	of	of	ADP
iajs-3524	71	8	high	high	ADJ
iajs-3524	71	9	-	-	PUNCT
iajs-3524	71	10	quality	quality	NOUN
iajs-3524	71	11	research	research	NOUN
iajs-3524	71	12	point	point	NOUN
iajs-3524	71	13	to	to	ADP
iajs-3524	71	14	a	a	DET
iajs-3524	71	15	relationship	relationship	NOUN
iajs-3524	71	16	between	between	ADP
iajs-3524	71	17	ra	ra	PROPN
iajs-3524	71	18	and	and	CCONJ
iajs-3524	71	19	the	the	DET
iajs-3524	71	20	onset	onset	NOUN
iajs-3524	71	21	of	of	ADP
iajs-3524	71	22	t2	t2	NOUN
iajs-3524	71	23	dm	dm	PROPN
iajs-3524	71	24	.	.	PUNCT
iajs-3524	72	1	the	the	DET
iajs-3524	72	2	potential	potential	ADJ
iajs-3524	72	3	relationship	relationship	NOUN
iajs-3524	72	4	between	between	ADP
iajs-3524	72	5	ra	ra	PROPN
iajs-3524	72	6	and	and	CCONJ
iajs-3524	72	7	incident	incident	NOUN
iajs-3524	72	8	t2	t2	NOUN
iajs-3524	72	9	dm	dm	PRON
iajs-3524	72	10	may	may	AUX
iajs-3524	72	11	be	be	AUX
iajs-3524	72	12	cause	cause	SCONJ
iajs-3524	72	13	by	by	ADP
iajs-3524	72	14	the	the	DET
iajs-3524	72	15	inflammatory	inflammatory	ADJ
iajs-3524	72	16	responses	response	NOUN
iajs-3524	72	17	that	that	PRON
iajs-3524	72	18	are	be	AUX
iajs-3524	72	19	triggered	trigger	VERB
iajs-3524	72	20	when	when	SCONJ
iajs-3524	72	21	both	both	DET
iajs-3524	72	22	diseases	disease	NOUN
iajs-3524	72	23	occur	occur	VERB
iajs-3524	72	24	.	.	PUNCT
iajs-3524	73	1	both	both	PRON
iajs-3524	73	2	t2	t2	PROPN
iajs-3524	73	3	dm	dm	PROPN
iajs-3524	73	4	and	and	CCONJ
iajs-3524	73	5	ra	ra	PROPN
iajs-3524	73	6	are	be	AUX
iajs-3524	73	7	strongly	strongly	ADV
iajs-3524	73	8	linked	link	VERB
iajs-3524	73	9	to	to	ADP
iajs-3524	73	10	persistent	persistent	ADJ
iajs-3524	73	11	inflammation	inflammation	NOUN
iajs-3524	73	12	throughout	throughout	ADP
iajs-3524	73	13	the	the	DET
iajs-3524	73	14	body	body	NOUN
iajs-3524	73	15	.	.	PUNCT
iajs-3524	74	1	moreover	moreover	ADV
iajs-3524	74	2	,	,	PUNCT
iajs-3524	74	3	ra	ra	PROPN
iajs-3524	74	4	has	have	AUX
iajs-3524	74	5	been	be	AUX
iajs-3524	74	6	linked	link	VERB
iajs-3524	74	7	to	to	ADP
iajs-3524	74	8	the	the	DET
iajs-3524	74	9	production	production	NOUN
iajs-3524	74	10	of	of	ADP
iajs-3524	74	11	proinflammatory	proinflammatory	ADJ
iajs-3524	74	12	cytokines	cytokine	NOUN
iajs-3524	74	13	such	such	ADJ
iajs-3524	74	14	as	as	ADP
iajs-3524	74	15	tnf	tnf	PROPN
iajs-3524	74	16	-	-	PUNCT
iajs-3524	74	17	α	α	PROPN
iajs-3524	74	18	and	and	CCONJ
iajs-3524	74	19	il-6	il-6	NOUN
iajs-3524	74	20	,	,	PUNCT
iajs-3524	74	21	which	which	PRON
iajs-3524	74	22	lead	lead	VERB
iajs-3524	74	23	to	to	ADP
iajs-3524	74	24	systemic	systemic	ADJ
iajs-3524	74	25	inflammation	inflammation	NOUN
iajs-3524	74	26	and	and	CCONJ
iajs-3524	74	27	insulin	insulin	NOUN
iajs-3524	74	28	resistance	resistance	NOUN
iajs-3524	74	29	.	.	PUNCT
iajs-3524	75	1	insulin	insulin	NOUN
iajs-3524	75	2	resistance	resistance	NOUN
iajs-3524	75	3	,	,	PUNCT
iajs-3524	75	4	in	in	ADP
iajs-3524	75	5	turn	turn	NOUN
iajs-3524	75	6	,	,	PUNCT
iajs-3524	75	7	contributes	contribute	VERB
iajs-3524	75	8	to	to	ADP
iajs-3524	75	9	t2	t2	NOUN
iajs-3524	75	10	dm	dm	NUM
iajs-3524	75	11	by	by	ADP
iajs-3524	75	12	blocking	block	VERB
iajs-3524	75	13	insulin	insulin	NOUN
iajs-3524	75	14	action	action	NOUN
iajs-3524	75	15	[	[	X
iajs-3524	75	16	15	15	NUM
iajs-3524	75	17	]	]	PUNCT
iajs-3524	75	18	.	.	PUNCT
iajs-3524	76	1	in	in	ADP
iajs-3524	76	2	addition	addition	NOUN
iajs-3524	76	3	,	,	PUNCT
iajs-3524	76	4	the	the	DET
iajs-3524	76	5	immune	immune	ADJ
iajs-3524	76	6	cells	cell	NOUN
iajs-3524	76	7	in	in	ADP
iajs-3524	76	8	the	the	DET
iajs-3524	76	9	liver	liver	NOUN
iajs-3524	76	10	produce	produce	VERB
iajs-3524	76	11	proinflammatory	proinflammatory	ADJ
iajs-3524	76	12	cytokines	cytokine	NOUN
iajs-3524	76	13	in	in	ADP
iajs-3524	76	14	response	response	NOUN
iajs-3524	76	15	to	to	ADP
iajs-3524	76	16	the	the	DET
iajs-3524	76	17	inflammatory	inflammatory	ADJ
iajs-3524	76	18	mediators	mediator	NOUN
iajs-3524	76	19	that	that	PRON
iajs-3524	76	20	are	be	AUX
iajs-3524	76	21	generated	generate	VERB
iajs-3524	76	22	by	by	ADP
iajs-3524	76	23	the	the	DET
iajs-3524	76	24	adipose	adipose	ADJ
iajs-3524	76	25	tissue	tissue	NOUN
iajs-3524	76	26	.	.	PUNCT
iajs-3524	77	1	the	the	DET
iajs-3524	77	2	development	development	NOUN
iajs-3524	77	3	of	of	ADP
iajs-3524	77	4	ra	ra	PROPN
iajs-3524	77	5	has	have	AUX
iajs-3524	77	6	been	be	AUX
iajs-3524	77	7	linked	link	VERB
iajs-3524	77	8	to	to	ADP
iajs-3524	77	9	a	a	DET
iajs-3524	77	10	wide	wide	ADJ
iajs-3524	77	11	variety	variety	NOUN
iajs-3524	77	12	of	of	ADP
iajs-3524	77	13	cytokines	cytokine	NOUN
iajs-3524	77	14	that	that	PRON
iajs-3524	77	15	promote	promote	VERB
iajs-3524	77	16	inflammation	inflammation	NOUN
iajs-3524	77	17	[	[	X
iajs-3524	77	18	16	16	NUM
iajs-3524	77	19	]	]	PUNCT
iajs-3524	77	20	.	.	PUNCT
iajs-3524	78	1	in	in	ADP
iajs-3524	78	2	individuals	individual	NOUN
iajs-3524	78	3	with	with	ADP
iajs-3524	78	4	ra	ra	PROPN
iajs-3524	78	5	,	,	PUNCT
iajs-3524	78	6	impaired	impaired	ADJ
iajs-3524	78	7	glucose	glucose	NOUN
iajs-3524	78	8	metabolism	metabolism	NOUN
iajs-3524	78	9	has	have	AUX
iajs-3524	78	10	been	be	AUX
iajs-3524	78	11	linked	link	VERB
iajs-3524	78	12	to	to	ADP
iajs-3524	78	13	both	both	CCONJ
iajs-3524	78	14	clinical	clinical	ADJ
iajs-3524	78	15	symptoms	symptom	NOUN
iajs-3524	78	16	that	that	PRON
iajs-3524	78	17	are	be	AUX
iajs-3524	78	18	difficult	difficult	ADJ
iajs-3524	78	19	to	to	PART
iajs-3524	78	20	control	control	VERB
iajs-3524	78	21	and	and	CCONJ
iajs-3524	78	22	a	a	DET
iajs-3524	78	23	considerably	considerably	ADV
iajs-3524	78	24	increased	increase	VERB
iajs-3524	78	25	risk	risk	NOUN
iajs-3524	78	26	of	of	ADP
iajs-3524	78	27	developing	develop	VERB
iajs-3524	78	28	t2	t2	NOUN
iajs-3524	78	29	dm	dm	NUM
iajs-3524	79	1	[	[	X
iajs-3524	79	2	17	17	NUM
iajs-3524	79	3	]	]	PUNCT
iajs-3524	79	4	.	.	PUNCT
iajs-3524	80	1	ihjpas	ihjpas	PROPN
iajs-3524	80	2	.	.	PUNCT
iajs-3524	81	1	2024	2024	NUM
iajs-3524	81	2	,	,	PUNCT
iajs-3524	81	3	37(4	37(4	NOUN
iajs-3524	81	4	)	)	PUNCT
iajs-3524	81	5	289	289	NUM
iajs-3524	81	6	the	the	DET
iajs-3524	81	7	cl-3	cl-3	NOUN
iajs-3524	81	8	and	and	CCONJ
iajs-3524	81	9	anti	anti	ADJ
iajs-3524	81	10	-	-	ADJ
iajs-3524	81	11	ccp	ccp	ADJ
iajs-3524	81	12	levels	level	NOUN
iajs-3524	81	13	are	be	AUX
iajs-3524	81	14	presented	present	VERB
iajs-3524	81	15	for	for	ADP
iajs-3524	81	16	all	all	PRON
iajs-3524	81	17	of	of	ADP
iajs-3524	81	18	the	the	DET
iajs-3524	81	19	groups	group	NOUN
iajs-3524	81	20	that	that	PRON
iajs-3524	81	21	are	be	AUX
iajs-3524	81	22	the	the	DET
iajs-3524	81	23	focus	focus	NOUN
iajs-3524	81	24	of	of	ADP
iajs-3524	81	25	this	this	DET
iajs-3524	81	26	inquiry	inquiry	NOUN
iajs-3524	81	27	in	in	ADP
iajs-3524	81	28	table	table	NOUN
iajs-3524	81	29	2	2	NUM
iajs-3524	81	30	.	.	PUNCT
iajs-3524	82	1	in	in	ADP
iajs-3524	82	2	table	table	NOUN
iajs-3524	82	3	1	1	NUM
iajs-3524	82	4	,	,	PUNCT
iajs-3524	82	5	patients	patient	NOUN
iajs-3524	82	6	with	with	ADP
iajs-3524	82	7	ra	ra	PROPN
iajs-3524	82	8	(	(	PUNCT
iajs-3524	82	9	g2	g2	PROPN
iajs-3524	82	10	)	)	PUNCT
iajs-3524	82	11	and	and	CCONJ
iajs-3524	82	12	patients	patient	NOUN
iajs-3524	82	13	with	with	ADP
iajs-3524	82	14	t2	t2	PROPN
iajs-3524	82	15	dm	dm	PROPN
iajs-3524	82	16	(	(	PUNCT
iajs-3524	82	17	g3	g3	PROPN
iajs-3524	82	18	)	)	PUNCT
iajs-3524	82	19	exhibited	exhibit	VERB
iajs-3524	82	20	anti	anti	ADJ
iajs-3524	82	21	-	-	ADJ
iajs-3524	82	22	ccp	ccp	ADJ
iajs-3524	82	23	levels	level	NOUN
iajs-3524	82	24	that	that	PRON
iajs-3524	82	25	were	be	AUX
iajs-3524	82	26	significantly	significantly	ADV
iajs-3524	82	27	greater	great	ADJ
iajs-3524	82	28	than	than	ADP
iajs-3524	82	29	those	those	PRON
iajs-3524	82	30	of	of	ADP
iajs-3524	82	31	the	the	DET
iajs-3524	82	32	controls	control	NOUN
iajs-3524	82	33	(	(	PUNCT
iajs-3524	82	34	g1	g1	PROPN
iajs-3524	82	35	)	)	PUNCT
iajs-3524	82	36	.	.	PUNCT
iajs-3524	83	1	in	in	ADP
iajs-3524	83	2	addition	addition	NOUN
iajs-3524	83	3	,	,	PUNCT
iajs-3524	83	4	in	in	ADP
iajs-3524	83	5	comparison	comparison	NOUN
iajs-3524	83	6	to	to	ADP
iajs-3524	83	7	g2	g2	PROPN
iajs-3524	83	8	,	,	PUNCT
iajs-3524	83	9	it	it	PRON
iajs-3524	83	10	was	be	AUX
iajs-3524	83	11	found	find	VERB
iajs-3524	83	12	that	that	SCONJ
iajs-3524	83	13	g3	g3	PROPN
iajs-3524	83	14	had	have	VERB
iajs-3524	83	15	a	a	DET
iajs-3524	83	16	substantially	substantially	ADV
iajs-3524	83	17	large	large	ADJ
iajs-3524	83	18	increase	increase	NOUN
iajs-3524	83	19	.	.	PUNCT
iajs-3524	84	1	table	table	NOUN
iajs-3524	84	2	2	2	NUM
iajs-3524	84	3	.	.	PUNCT
iajs-3524	84	4	levels	level	NOUN
iajs-3524	84	5	of	of	ADP
iajs-3524	84	6	anti	anti	ADJ
iajs-3524	84	7	-	-	ADJ
iajs-3524	84	8	ccp	ccp	ADJ
iajs-3524	84	9	and	and	CCONJ
iajs-3524	84	10	cl-3	cl-3	X
iajs-3524	84	11	in	in	ADP
iajs-3524	84	12	the	the	DET
iajs-3524	84	13	studied	study	VERB
iajs-3524	84	14	groups	group	NOUN
iajs-3524	84	15	.	.	PUNCT
iajs-3524	85	1	parameter	parameter	PROPN
iajs-3524	85	2	mean±	mean±	PROPN
iajs-3524	85	3	sd	sd	ADP
iajs-3524	85	4	p	p	NOUN
iajs-3524	85	5	-	-	PUNCT
iajs-3524	85	6	value	value	NOUN
iajs-3524	85	7	g1	g1	NOUN
iajs-3524	85	8	(	(	PUNCT
iajs-3524	85	9	n=50	n=50	ADJ
iajs-3524	85	10	)	)	PUNCT
iajs-3524	85	11	g2	g2	PROPN
iajs-3524	85	12	(	(	PUNCT
iajs-3524	85	13	n=50	n=50	PROPN
iajs-3524	85	14	)	)	PUNCT
iajs-3524	85	15	g3	g3	NOUN
iajs-3524	85	16	(	(	PUNCT
iajs-3524	85	17	n=50	n=50	ADJ
iajs-3524	85	18	)	)	PUNCT
iajs-3524	85	19	g1	g1	PROPN
iajs-3524	85	20	&	&	CCONJ
iajs-3524	85	21	g2	g2	PROPN
iajs-3524	85	22	g1	g1	PROPN
iajs-3524	85	23	&	&	CCONJ
iajs-3524	85	24	g3	g3	PROPN
iajs-3524	85	25	g2	g2	PROPN
iajs-3524	85	26	&	&	CCONJ
iajs-3524	85	27	g3	g3	PROPN
iajs-3524	85	28	anti	anti	PROPN
iajs-3524	85	29	-	-	ADJ
iajs-3524	85	30	ccp	ccp	ADJ
iajs-3524	85	31	(	(	PUNCT
iajs-3524	85	32	u	u	NOUN
iajs-3524	85	33	/	/	SYM
iajs-3524	85	34	ml	ml	PROPN
iajs-3524	85	35	)	)	PUNCT
iajs-3524	86	1	0.31±0.09	0.31±0.09	PROPN
iajs-3524	86	2	0.61±0.52	0.61±0.52	PROPN
iajs-3524	86	3	0.74±0.15	0.74±0.15	PROPN
iajs-3524	87	1	hs	hs	PROPN
iajs-3524	88	1	hs	hs	PROPN
iajs-3524	88	2	hs	hs	PROPN
iajs-3524	88	3	cl-3	cl-3	PROPN
iajs-3524	88	4	(	(	PUNCT
iajs-3524	88	5	ρg	ρg	NOUN
iajs-3524	88	6	/	/	SYM
iajs-3524	88	7	ml	ml	NOUN
iajs-3524	88	8	)	)	PUNCT
iajs-3524	88	9	963.99±149.49	963.99±149.49	NUM
iajs-3524	88	10	3037.75±1452.64	3037.75±1452.64	NUM
iajs-3524	88	11	4013.49±2181.23	4013.49±2181.23	INTJ
iajs-3524	88	12	hs	hs	INTJ
iajs-3524	88	13	hs	hs	PROPN
iajs-3524	88	14	hs	hs	PROPN
iajs-3524	88	15	*	*	PROPN
iajs-3524	88	16	*	*	PROPN
iajs-3524	88	17	hs	hs	ADJ
iajs-3524	88	18	:	:	PUNCT
iajs-3524	88	19	high	high	ADJ
iajs-3524	88	20	significantly	significantly	ADV
iajs-3524	88	21	at	at	ADP
iajs-3524	88	22	the	the	DET
iajs-3524	88	23	0.01	0.01	NUM
iajs-3524	88	24	level	level	NOUN
iajs-3524	88	25	.	.	PUNCT
iajs-3524	89	1	the	the	DET
iajs-3524	89	2	peculiar	peculiar	ADJ
iajs-3524	89	3	amino	amino	NOUN
iajs-3524	89	4	acid	acid	NOUN
iajs-3524	89	5	citrulline	citrulline	NOUN
iajs-3524	89	6	is	be	AUX
iajs-3524	89	7	one	one	NUM
iajs-3524	89	8	of	of	ADP
iajs-3524	89	9	the	the	DET
iajs-3524	89	10	antigenic	antigenic	ADJ
iajs-3524	89	11	determinants	determinant	NOUN
iajs-3524	89	12	that	that	PRON
iajs-3524	89	13	may	may	AUX
iajs-3524	89	14	be	be	AUX
iajs-3524	89	15	bound	bind	VERB
iajs-3524	89	16	by	by	ADP
iajs-3524	89	17	autoantibodies	autoantibody	NOUN
iajs-3524	89	18	that	that	PRON
iajs-3524	89	19	are	be	AUX
iajs-3524	89	20	directed	direct	VERB
iajs-3524	89	21	against	against	ADP
iajs-3524	89	22	anti	anti	NOUN
iajs-3524	89	23	-	-	NOUN
iajs-3524	89	24	ccp	ccp	X
iajs-3524	89	25	.	.	PUNCT
iajs-3524	90	1	although	although	SCONJ
iajs-3524	90	2	it	it	PRON
iajs-3524	90	3	is	be	AUX
iajs-3524	90	4	possible	possible	ADJ
iajs-3524	90	5	to	to	PART
iajs-3524	90	6	praduce	praduce	VERB
iajs-3524	90	7	amino	amino	NOUN
iajs-3524	90	8	acids	acid	NOUN
iajs-3524	90	9	by	by	ADP
iajs-3524	90	10	post	post	ADJ
iajs-3524	90	11	-	-	ADJ
iajs-3524	90	12	translational	translational	ADJ
iajs-3524	90	13	modification	modification	NOUN
iajs-3524	90	14	,	,	PUNCT
iajs-3524	90	15	the	the	DET
iajs-3524	90	16	amino	amino	NOUN
iajs-3524	90	17	acid	acid	NOUN
iajs-3524	90	18	is	be	AUX
iajs-3524	90	19	not	not	PART
iajs-3524	90	20	incorporated	incorporate	VERB
iajs-3524	90	21	into	into	ADP
iajs-3524	90	22	the	the	DET
iajs-3524	90	23	protein	protein	NOUN
iajs-3524	90	24	during	during	ADP
iajs-3524	90	25	the	the	DET
iajs-3524	90	26	synthesis	synthesis	NOUN
iajs-3524	90	27	process	process	NOUN
iajs-3524	90	28	itself	itself	PRON
iajs-3524	90	29	.	.	PUNCT
iajs-3524	91	1	this	this	PRON
iajs-3524	91	2	is	be	AUX
iajs-3524	91	3	because	because	SCONJ
iajs-3524	91	4	post	post	ADJ
iajs-3524	91	5	-	-	ADJ
iajs-3524	91	6	translational	translational	ADJ
iajs-3524	91	7	modification	modification	NOUN
iajs-3524	91	8	is	be	AUX
iajs-3524	91	9	a	a	DET
iajs-3524	91	10	process	process	NOUN
iajs-3524	91	11	that	that	PRON
iajs-3524	91	12	occurs	occur	VERB
iajs-3524	91	13	after	after	SCONJ
iajs-3524	91	14	translation	translation	NOUN
iajs-3524	91	15	has	have	AUX
iajs-3524	91	16	taken	take	VERB
iajs-3524	91	17	place	place	NOUN
iajs-3524	91	18	.	.	PUNCT
iajs-3524	92	1	this	this	PRON
iajs-3524	92	2	is	be	AUX
iajs-3524	92	3	because	because	SCONJ
iajs-3524	92	4	the	the	DET
iajs-3524	92	5	amino	amino	NOUN
iajs-3524	92	6	acid	acid	NOUN
iajs-3524	92	7	is	be	AUX
iajs-3524	92	8	not	not	PART
iajs-3524	92	9	produced	produce	VERB
iajs-3524	92	10	until	until	ADP
iajs-3524	92	11	after	after	SCONJ
iajs-3524	92	12	the	the	DET
iajs-3524	92	13	synthesis	synthesis	NOUN
iajs-3524	92	14	of	of	ADP
iajs-3524	92	15	the	the	DET
iajs-3524	92	16	protein	protein	NOUN
iajs-3524	92	17	has	have	AUX
iajs-3524	92	18	taken	take	VERB
iajs-3524	92	19	place	place	NOUN
iajs-3524	92	20	.	.	PUNCT
iajs-3524	93	1	citrullination	citrullination	NOUN
iajs-3524	93	2	is	be	AUX
iajs-3524	93	3	a	a	DET
iajs-3524	93	4	process	process	NOUN
iajs-3524	93	5	that	that	PRON
iajs-3524	93	6	involves	involve	VERB
iajs-3524	93	7	the	the	DET
iajs-3524	93	8	hydrolysis	hydrolysis	NOUN
iajs-3524	93	9	of	of	ADP
iajs-3524	93	10	the	the	DET
iajs-3524	93	11	positively	positively	ADV
iajs-3524	93	12	charged	charge	VERB
iajs-3524	93	13	nh2	nh2	NOUN
iajs-3524	93	14	–	–	PUNCT
iajs-3524	93	15	group	group	NOUN
iajs-3524	93	16	that	that	PRON
iajs-3524	93	17	is	be	AUX
iajs-3524	93	18	present	present	ADJ
iajs-3524	93	19	in	in	ADP
iajs-3524	93	20	the	the	DET
iajs-3524	93	21	amino	amino	NOUN
iajs-3524	93	22	acid	acid	NOUN
iajs-3524	93	23	arginine	arginine	NOUN
iajs-3524	93	24	into	into	ADP
iajs-3524	93	25	a	a	DET
iajs-3524	93	26	neutral	neutral	ADJ
iajs-3524	93	27	oxygen	oxygen	NOUN
iajs-3524	93	28	group	group	NOUN
iajs-3524	93	29	.	.	PUNCT
iajs-3524	94	1	this	this	DET
iajs-3524	94	2	process	process	NOUN
iajs-3524	94	3	is	be	AUX
iajs-3524	94	4	catalyzed	catalyze	VERB
iajs-3524	94	5	by	by	ADP
iajs-3524	94	6	enzymes	enzyme	NOUN
iajs-3524	94	7	.	.	PUNCT
iajs-3524	95	1	this	this	DET
iajs-3524	95	2	method	method	NOUN
iajs-3524	95	3	is	be	AUX
iajs-3524	95	4	also	also	ADV
iajs-3524	95	5	known	know	VERB
iajs-3524	95	6	as	as	ADP
iajs-3524	95	7	deamination	deamination	NOUN
iajs-3524	95	8	in	in	ADP
iajs-3524	95	9	certain	certain	ADJ
iajs-3524	95	10	circles	circle	NOUN
iajs-3524	95	11	.	.	PUNCT
iajs-3524	96	1	people	people	NOUN
iajs-3524	96	2	who	who	PRON
iajs-3524	96	3	suffer	suffer	VERB
iajs-3524	96	4	from	from	ADP
iajs-3524	96	5	ra	ra	PROPN
iajs-3524	96	6	are	be	AUX
iajs-3524	96	7	more	more	ADV
iajs-3524	96	8	likely	likely	ADJ
iajs-3524	96	9	to	to	PART
iajs-3524	96	10	develop	develop	VERB
iajs-3524	96	11	autoantibodies	autoantibody	NOUN
iajs-3524	96	12	because	because	SCONJ
iajs-3524	96	13	these	these	DET
iajs-3524	96	14	antibodies	antibody	NOUN
iajs-3524	96	15	can	can	AUX
iajs-3524	96	16	detect	detect	VERB
iajs-3524	96	17	a	a	DET
iajs-3524	96	18	particular	particular	ADJ
iajs-3524	96	19	oxygen	oxygen	NOUN
iajs-3524	96	20	group	group	NOUN
iajs-3524	96	21	included	include	VERB
iajs-3524	96	22	inside	inside	ADP
iajs-3524	96	23	peptidyl	peptidyl	NOUN
iajs-3524	96	24	citrulline	citrulline	NOUN
iajs-3524	96	25	.	.	PUNCT
iajs-3524	97	1	citrulline	citrulline	NOUN
iajs-3524	97	2	residues	residue	NOUN
iajs-3524	97	3	,	,	PUNCT
iajs-3524	97	4	which	which	PRON
iajs-3524	97	5	are	be	AUX
iajs-3524	97	6	a	a	DET
iajs-3524	97	7	key	key	ADJ
iajs-3524	97	8	component	component	NOUN
iajs-3524	97	9	of	of	ADP
iajs-3524	97	10	antigenic	antigenic	ADJ
iajs-3524	97	11	determinants	determinant	NOUN
iajs-3524	97	12	such	such	ADJ
iajs-3524	97	13	as	as	ADP
iajs-3524	97	14	these	these	PRON
iajs-3524	97	15	,	,	PUNCT
iajs-3524	97	16	are	be	AUX
iajs-3524	97	17	one	one	NUM
iajs-3524	97	18	of	of	ADP
iajs-3524	97	19	the	the	DET
iajs-3524	97	20	antigenic	antigenic	ADJ
iajs-3524	97	21	determinants	determinant	NOUN
iajs-3524	97	22	that	that	PRON
iajs-3524	97	23	may	may	AUX
iajs-3524	97	24	be	be	AUX
iajs-3524	97	25	identified	identify	VERB
iajs-3524	97	26	by	by	ADP
iajs-3524	97	27	ra	ra	PROPN
iajs-3524	97	28	antibodies	antibodie	VERB
iajs-3524	97	29	.	.	PUNCT
iajs-3524	98	1	anti	anti	ADJ
iajs-3524	98	2	-	-	ADJ
iajs-3524	98	3	ccp	ccp	ADJ
iajs-3524	98	4	testing	testing	NOUN
iajs-3524	98	5	is	be	AUX
iajs-3524	98	6	particularly	particularly	ADV
iajs-3524	98	7	helpful	helpful	ADJ
iajs-3524	98	8	in	in	ADP
iajs-3524	98	9	the	the	DET
iajs-3524	98	10	diagnosis	diagnosis	NOUN
iajs-3524	98	11	of	of	ADP
iajs-3524	98	12	ra	ra	PROPN
iajs-3524	99	1	[	[	X
iajs-3524	99	2	18	18	NUM
iajs-3524	99	3	]	]	PUNCT
iajs-3524	99	4	due	due	ADP
iajs-3524	99	5	to	to	ADP
iajs-3524	99	6	its	its	PRON
iajs-3524	99	7	high	high	ADJ
iajs-3524	99	8	specificity	specificity	NOUN
iajs-3524	99	9	early	early	ADV
iajs-3524	99	10	on	on	ADV
iajs-3524	99	11	in	in	ADP
iajs-3524	99	12	the	the	DET
iajs-3524	99	13	progression	progression	NOUN
iajs-3524	99	14	of	of	ADP
iajs-3524	99	15	the	the	DET
iajs-3524	99	16	disease	disease	NOUN
iajs-3524	99	17	as	as	ADV
iajs-3524	99	18	well	well	ADV
iajs-3524	99	19	as	as	ADP
iajs-3524	99	20	its	its	PRON
iajs-3524	99	21	ability	ability	NOUN
iajs-3524	99	22	to	to	PART
iajs-3524	99	23	identify	identify	VERB
iajs-3524	99	24	those	those	PRON
iajs-3524	99	25	who	who	PRON
iajs-3524	99	26	are	be	AUX
iajs-3524	99	27	likely	likely	ADJ
iajs-3524	99	28	to	to	PART
iajs-3524	99	29	suffer	suffer	VERB
iajs-3524	99	30	from	from	ADP
iajs-3524	99	31	significant	significant	ADJ
iajs-3524	99	32	sickness	sickness	NOUN
iajs-3524	99	33	and	and	CCONJ
iajs-3524	99	34	damage	damage	NOUN
iajs-3524	99	35	that	that	PRON
iajs-3524	99	36	can	can	AUX
iajs-3524	99	37	not	not	PART
iajs-3524	99	38	be	be	AUX
iajs-3524	99	39	repaired	repair	VERB
iajs-3524	99	40	.	.	PUNCT
iajs-3524	100	1	both	both	PRON
iajs-3524	100	2	of	of	ADP
iajs-3524	100	3	these	these	DET
iajs-3524	100	4	qualities	quality	NOUN
iajs-3524	100	5	are	be	AUX
iajs-3524	100	6	important	important	ADJ
iajs-3524	100	7	in	in	ADP
iajs-3524	100	8	determining	determine	VERB
iajs-3524	100	9	who	who	PRON
iajs-3524	100	10	will	will	AUX
iajs-3524	100	11	ultimately	ultimately	ADV
iajs-3524	100	12	be	be	AUX
iajs-3524	100	13	affected	affect	VERB
iajs-3524	100	14	by	by	ADP
iajs-3524	100	15	ra	ra	PROPN
iajs-3524	100	16	.	.	PUNCT
iajs-3524	101	1	both	both	PRON
iajs-3524	101	2	of	of	ADP
iajs-3524	101	3	these	these	DET
iajs-3524	101	4	symptoms	symptom	NOUN
iajs-3524	101	5	may	may	AUX
iajs-3524	101	6	be	be	AUX
iajs-3524	101	7	seen	see	VERB
iajs-3524	101	8	in	in	ADP
iajs-3524	101	9	a	a	DET
iajs-3524	101	10	patient	patient	NOUN
iajs-3524	101	11	who	who	PRON
iajs-3524	101	12	is	be	AUX
iajs-3524	101	13	at	at	ADP
iajs-3524	101	14	an	an	DET
iajs-3524	101	15	early	early	ADJ
iajs-3524	101	16	stage	stage	NOUN
iajs-3524	101	17	of	of	ADP
iajs-3524	101	18	the	the	DET
iajs-3524	101	19	disease	disease	NOUN
iajs-3524	101	20	's	's	PART
iajs-3524	101	21	development	development	NOUN
iajs-3524	101	22	[	[	X
iajs-3524	101	23	19	19	NUM
iajs-3524	101	24	]	]	PUNCT
iajs-3524	101	25	.	.	PUNCT
iajs-3524	102	1	the	the	DET
iajs-3524	102	2	data	datum	NOUN
iajs-3524	102	3	that	that	PRON
iajs-3524	102	4	are	be	AUX
iajs-3524	102	5	presented	present	VERB
iajs-3524	102	6	in	in	ADP
iajs-3524	102	7	table	table	NOUN
iajs-3524	102	8	2	2	NUM
iajs-3524	102	9	for	for	ADP
iajs-3524	102	10	cl-3	cl-3	PRON
iajs-3524	102	11	illustrate	illustrate	VERB
iajs-3524	102	12	that	that	DET
iajs-3524	102	13	g3	g3	PROPN
iajs-3524	102	14	has	have	AUX
iajs-3524	102	15	risen	rise	VERB
iajs-3524	102	16	in	in	ADP
iajs-3524	102	17	a	a	DET
iajs-3524	102	18	manner	manner	NOUN
iajs-3524	102	19	that	that	PRON
iajs-3524	102	20	is	be	AUX
iajs-3524	102	21	statistically	statistically	ADV
iajs-3524	102	22	significant	significant	ADJ
iajs-3524	102	23	when	when	SCONJ
iajs-3524	102	24	compared	compare	VERB
iajs-3524	102	25	to	to	ADP
iajs-3524	102	26	the	the	DET
iajs-3524	102	27	prior	prior	ADJ
iajs-3524	102	28	value	value	NOUN
iajs-3524	102	29	.	.	PUNCT
iajs-3524	103	1	this	this	PRON
iajs-3524	103	2	is	be	AUX
iajs-3524	103	3	shown	show	VERB
iajs-3524	103	4	by	by	ADP
iajs-3524	103	5	the	the	DET
iajs-3524	103	6	comparison	comparison	NOUN
iajs-3524	103	7	of	of	ADP
iajs-3524	103	8	g3	g3	PROPN
iajs-3524	103	9	to	to	ADP
iajs-3524	103	10	g2	g2	PROPN
iajs-3524	103	11	and	and	CCONJ
iajs-3524	103	12	g1	g1	PROPN
iajs-3524	103	13	,	,	PUNCT
iajs-3524	103	14	which	which	PRON
iajs-3524	103	15	are	be	AUX
iajs-3524	103	16	both	both	PRON
iajs-3524	103	17	displayed	display	VERB
iajs-3524	103	18	in	in	ADP
iajs-3524	103	19	the	the	DET
iajs-3524	103	20	table	table	NOUN
iajs-3524	103	21	.	.	PUNCT
iajs-3524	104	1	in	in	ADP
iajs-3524	104	2	addition	addition	NOUN
iajs-3524	104	3	to	to	ADP
iajs-3524	104	4	this	this	PRON
iajs-3524	104	5	,	,	PUNCT
iajs-3524	104	6	it	it	PRON
iajs-3524	104	7	was	be	AUX
iajs-3524	104	8	discovered	discover	VERB
iajs-3524	104	9	that	that	SCONJ
iajs-3524	104	10	g2	g2	PROPN
iajs-3524	104	11	had	have	AUX
iajs-3524	104	12	significantly	significantly	ADV
iajs-3524	104	13	improved	improve	VERB
iajs-3524	104	14	in	in	ADP
iajs-3524	104	15	contrast	contrast	NOUN
iajs-3524	104	16	to	to	ADP
iajs-3524	104	17	g1	g1	PROPN
iajs-3524	104	18	's	's	PART
iajs-3524	104	19	performance	performance	NOUN
iajs-3524	104	20	.	.	PUNCT
iajs-3524	105	1	people	people	NOUN
iajs-3524	105	2	who	who	PRON
iajs-3524	105	3	have	have	VERB
iajs-3524	105	4	t2	t2	NOUN
iajs-3524	105	5	dm	dm	AUX
iajs-3524	105	6	have	have	VERB
iajs-3524	105	7	an	an	DET
iajs-3524	105	8	increased	increase	VERB
iajs-3524	105	9	risk	risk	NOUN
iajs-3524	105	10	of	of	ADP
iajs-3524	105	11	experiencing	experience	VERB
iajs-3524	105	12	a	a	DET
iajs-3524	105	13	rapid	rapid	ADJ
iajs-3524	105	14	deterioration	deterioration	NOUN
iajs-3524	105	15	of	of	ADP
iajs-3524	105	16	the	the	DET
iajs-3524	105	17	knee	knee	NOUN
iajs-3524	105	18	cartilage	cartilage	NOUN
iajs-3524	105	19	[	[	X
iajs-3524	105	20	20	20	NUM
iajs-3524	105	21	]	]	PUNCT
iajs-3524	105	22	,	,	PUNCT
iajs-3524	105	23	which	which	PRON
iajs-3524	105	24	is	be	AUX
iajs-3524	105	25	now	now	ADV
iajs-3524	105	26	the	the	DET
iajs-3524	105	27	issue	issue	NOUN
iajs-3524	105	28	that	that	PRON
iajs-3524	105	29	attracts	attract	VERB
iajs-3524	105	30	the	the	DET
iajs-3524	105	31	most	most	ADJ
iajs-3524	105	32	attention	attention	NOUN
iajs-3524	105	33	.	.	PUNCT
iajs-3524	106	1	in	in	ADP
iajs-3524	106	2	particular	particular	ADJ
iajs-3524	106	3	,	,	PUNCT
iajs-3524	106	4	mmps	mmp	NOUN
iajs-3524	106	5	are	be	AUX
iajs-3524	106	6	anticipated	anticipate	VERB
iajs-3524	106	7	to	to	PART
iajs-3524	106	8	play	play	VERB
iajs-3524	106	9	a	a	DET
iajs-3524	106	10	significant	significant	ADJ
iajs-3524	106	11	role	role	NOUN
iajs-3524	106	12	in	in	ADP
iajs-3524	106	13	the	the	DET
iajs-3524	106	14	process	process	NOUN
iajs-3524	106	15	of	of	ADP
iajs-3524	106	16	cartilage	cartilage	NOUN
iajs-3524	106	17	disintegration	disintegration	NOUN
iajs-3524	106	18	during	during	ADP
iajs-3524	106	19	the	the	DET
iajs-3524	106	20	induction	induction	NOUN
iajs-3524	106	21	of	of	ADP
iajs-3524	106	22	degenerative	degenerative	ADJ
iajs-3524	106	23	cartilage	cartilage	NOUN
iajs-3524	106	24	alterations	alteration	NOUN
iajs-3524	106	25	that	that	PRON
iajs-3524	106	26	occur	occur	VERB
iajs-3524	106	27	as	as	ADP
iajs-3524	106	28	a	a	DET
iajs-3524	106	29	result	result	NOUN
iajs-3524	106	30	of	of	ADP
iajs-3524	106	31	oa	oa	PRON
iajs-3524	107	1	[	[	X
iajs-3524	107	2	21	21	NUM
iajs-3524	107	3	]	]	PUNCT
iajs-3524	107	4	.	.	PUNCT
iajs-3524	108	1	this	this	PRON
iajs-3524	108	2	is	be	AUX
iajs-3524	108	3	because	because	SCONJ
iajs-3524	108	4	mmps	mmp	NOUN
iajs-3524	108	5	are	be	AUX
iajs-3524	108	6	known	know	VERB
iajs-3524	108	7	to	to	PART
iajs-3524	108	8	have	have	VERB
iajs-3524	108	9	a	a	DET
iajs-3524	108	10	significant	significant	ADJ
iajs-3524	108	11	role	role	NOUN
iajs-3524	108	12	in	in	ADP
iajs-3524	108	13	the	the	DET
iajs-3524	108	14	progression	progression	NOUN
iajs-3524	108	15	of	of	ADP
iajs-3524	108	16	oa	oa	INTJ
iajs-3524	108	17	.	.	PUNCT
iajs-3524	109	1	this	this	PRON
iajs-3524	109	2	is	be	AUX
iajs-3524	109	3	because	because	SCONJ
iajs-3524	109	4	osteoarthritis	osteoarthritis	NOUN
iajs-3524	109	5	is	be	AUX
iajs-3524	109	6	known	know	VERB
iajs-3524	109	7	to	to	PART
iajs-3524	109	8	produce	produce	VERB
iajs-3524	109	9	changes	change	NOUN
iajs-3524	109	10	to	to	ADP
iajs-3524	109	11	the	the	DET
iajs-3524	109	12	cartilage	cartilage	NOUN
iajs-3524	109	13	,	,	PUNCT
iajs-3524	109	14	which	which	PRON
iajs-3524	109	15	may	may	AUX
iajs-3524	109	16	result	result	VERB
iajs-3524	109	17	in	in	ADP
iajs-3524	109	18	discomfort	discomfort	NOUN
iajs-3524	109	19	and	and	CCONJ
iajs-3524	109	20	stiffness	stiffness	NOUN
iajs-3524	109	21	in	in	ADP
iajs-3524	109	22	the	the	DET
iajs-3524	109	23	joints	joint	NOUN
iajs-3524	109	24	.	.	PUNCT
iajs-3524	110	1	the	the	DET
iajs-3524	110	2	mmps	mmp	NOUN
iajs-3524	110	3	are	be	AUX
iajs-3524	110	4	the	the	DET
iajs-3524	110	5	primary	primary	ADJ
iajs-3524	110	6	proteolytic	proteolytic	ADJ
iajs-3524	110	7	enzymes	enzyme	NOUN
iajs-3524	110	8	of	of	ADP
iajs-3524	110	9	these	these	DET
iajs-3524	110	10	proteins	protein	NOUN
iajs-3524	110	11	;	;	PUNCT
iajs-3524	110	12	they	they	PRON
iajs-3524	110	13	can	can	AUX
iajs-3524	110	14	destroy	destroy	VERB
iajs-3524	110	15	type	type	PROPN
iajs-3524	110	16	ii	ii	PROPN
iajs-3524	110	17	fibrillar	fibrillar	ADJ
iajs-3524	110	18	collagen	collagen	NOUN
iajs-3524	110	19	,	,	PUNCT
iajs-3524	110	20	in	in	ADP
iajs-3524	110	21	addition	addition	NOUN
iajs-3524	110	22	to	to	ADP
iajs-3524	110	23	collagen	collagen	NOUN
iajs-3524	110	24	types	type	NOUN
iajs-3524	110	25	ix	ix	ADP
iajs-3524	110	26	,	,	PUNCT
iajs-3524	110	27	xi	xi	PROPN
iajs-3524	110	28	,	,	PUNCT
iajs-3524	110	29	and	and	CCONJ
iajs-3524	110	30	vi	vi	NOUN
iajs-3524	110	31	,	,	PUNCT
iajs-3524	110	32	as	as	ADV
iajs-3524	110	33	well	well	ADV
iajs-3524	110	34	as	as	ADP
iajs-3524	110	35	extra	extra	ADJ
iajs-3524	110	36	secondary	secondary	ADJ
iajs-3524	110	37	collagens	collagen	NOUN
iajs-3524	111	1	[	[	X
iajs-3524	111	2	22,23	22,23	NOUN
iajs-3524	111	3	]	]	PUNCT
iajs-3524	111	4	.	.	PUNCT
iajs-3524	112	1	they	they	PRON
iajs-3524	112	2	also	also	ADV
iajs-3524	112	3	have	have	VERB
iajs-3524	112	4	the	the	DET
iajs-3524	112	5	ihjpas	ihjpa	NOUN
iajs-3524	112	6	.	.	PUNCT
iajs-3524	113	1	2024	2024	NUM
iajs-3524	113	2	,	,	PUNCT
iajs-3524	113	3	37(4	37(4	NOUN
iajs-3524	113	4	)	)	PUNCT
iajs-3524	113	5	290	290	NUM
iajs-3524	113	6	potential	potential	NOUN
iajs-3524	113	7	to	to	PART
iajs-3524	113	8	cleave	cleave	VERB
iajs-3524	113	9	additional	additional	ADJ
iajs-3524	113	10	secondary	secondary	ADJ
iajs-3524	113	11	collagens	collagen	NOUN
iajs-3524	113	12	.	.	PUNCT
iajs-3524	114	1	it	it	PRON
iajs-3524	114	2	is	be	AUX
iajs-3524	114	3	plausible	plausible	ADJ
iajs-3524	114	4	to	to	PART
iajs-3524	114	5	infer	infer	VERB
iajs-3524	114	6	that	that	SCONJ
iajs-3524	114	7	this	this	PRON
iajs-3524	114	8	is	be	AUX
iajs-3524	114	9	the	the	DET
iajs-3524	114	10	case	case	NOUN
iajs-3524	114	11	given	give	VERB
iajs-3524	114	12	that	that	SCONJ
iajs-3524	114	13	the	the	DET
iajs-3524	114	14	majority	majority	NOUN
iajs-3524	114	15	of	of	ADP
iajs-3524	114	16	cartilage	cartilage	NOUN
iajs-3524	114	17	's	's	PART
iajs-3524	114	18	extracellular	extracellular	ADJ
iajs-3524	114	19	matrix	matrix	NOUN
iajs-3524	114	20	is	be	AUX
iajs-3524	114	21	made	make	VERB
iajs-3524	114	22	up	up	ADP
iajs-3524	114	23	of	of	ADP
iajs-3524	114	24	proteoglycans	proteoglycan	NOUN
iajs-3524	114	25	,	,	PUNCT
iajs-3524	114	26	which	which	PRON
iajs-3524	114	27	are	be	AUX
iajs-3524	114	28	made	make	VERB
iajs-3524	114	29	up	up	ADP
iajs-3524	114	30	of	of	ADP
iajs-3524	114	31	collagen	collagen	NOUN
iajs-3524	114	32	.	.	PUNCT
iajs-3524	115	1	in	in	ADP
iajs-3524	115	2	addition	addition	NOUN
iajs-3524	115	3	to	to	ADP
iajs-3524	115	4	this	this	PRON
iajs-3524	115	5	,	,	PUNCT
iajs-3524	115	6	mmp-13	mmp-13	PROPN
iajs-3524	115	7	was	be	AUX
iajs-3524	115	8	shown	show	VERB
iajs-3524	115	9	to	to	PART
iajs-3524	115	10	be	be	AUX
iajs-3524	115	11	present	present	ADJ
iajs-3524	115	12	in	in	ADP
iajs-3524	115	13	the	the	DET
iajs-3524	115	14	synovial	synovial	ADJ
iajs-3524	115	15	tissue	tissue	NOUN
iajs-3524	115	16	of	of	ADP
iajs-3524	115	17	persons	person	NOUN
iajs-3524	115	18	who	who	PRON
iajs-3524	115	19	had	have	VERB
iajs-3524	115	20	either	either	CCONJ
iajs-3524	115	21	oa	oa	PROPN
iajs-3524	115	22	or	or	CCONJ
iajs-3524	115	23	ra	ra	PROPN
iajs-3524	116	1	[	[	X
iajs-3524	116	2	24	24	NUM
iajs-3524	116	3	]	]	PUNCT
iajs-3524	116	4	.	.	PUNCT
iajs-3524	117	1	it	it	PRON
iajs-3524	117	2	has	have	AUX
iajs-3524	117	3	been	be	AUX
iajs-3524	117	4	shown	show	VERB
iajs-3524	117	5	that	that	SCONJ
iajs-3524	117	6	cl-3	cl-3	PRON
iajs-3524	117	7	is	be	AUX
iajs-3524	117	8	capable	capable	ADJ
iajs-3524	117	9	of	of	ADP
iajs-3524	117	10	degrading	degrade	VERB
iajs-3524	117	11	types	type	NOUN
iajs-3524	117	12	i	i	PRON
iajs-3524	117	13	,	,	PUNCT
iajs-3524	117	14	ii	ii	PROPN
iajs-3524	117	15	,	,	PUNCT
iajs-3524	117	16	and	and	CCONJ
iajs-3524	117	17	iii	iii	X
iajs-3524	117	18	of	of	ADP
iajs-3524	117	19	collagen	collagen	NOUN
iajs-3524	117	20	,	,	PUNCT
iajs-3524	117	21	in	in	ADP
iajs-3524	117	22	addition	addition	NOUN
iajs-3524	117	23	to	to	ADP
iajs-3524	117	24	cartilage	cartilage	NOUN
iajs-3524	117	25	proteoglycan	proteoglycan	ADJ
iajs-3524	117	26	aggrecans	aggrecan	NOUN
iajs-3524	117	27	.	.	PUNCT
iajs-3524	118	1	the	the	DET
iajs-3524	118	2	characterization	characterization	NOUN
iajs-3524	118	3	of	of	ADP
iajs-3524	118	4	cl-3	cl-3	NOUN
iajs-3524	118	5	by	by	ADP
iajs-3524	118	6	the	the	DET
iajs-3524	118	7	use	use	NOUN
iajs-3524	118	8	of	of	ADP
iajs-3524	118	9	biochemical	biochemical	ADJ
iajs-3524	118	10	methods	method	NOUN
iajs-3524	118	11	showed	show	VERB
iajs-3524	118	12	that	that	SCONJ
iajs-3524	118	13	it	it	PRON
iajs-3524	118	14	participates	participate	VERB
iajs-3524	118	15	in	in	ADP
iajs-3524	118	16	a	a	DET
iajs-3524	118	17	wide	wide	ADJ
iajs-3524	118	18	range	range	NOUN
iajs-3524	118	19	of	of	ADP
iajs-3524	118	20	actions	action	NOUN
iajs-3524	118	21	that	that	PRON
iajs-3524	118	22	are	be	AUX
iajs-3524	118	23	aimed	aim	VERB
iajs-3524	118	24	at	at	ADP
iajs-3524	118	25	the	the	DET
iajs-3524	118	26	components	component	NOUN
iajs-3524	118	27	of	of	ADP
iajs-3524	118	28	connective	connective	ADJ
iajs-3524	118	29	tissue	tissue	NOUN
iajs-3524	118	30	.	.	PUNCT
iajs-3524	119	1	because	because	SCONJ
iajs-3524	119	2	cl-3	cl-3	PRON
iajs-3524	119	3	prefers	prefer	VERB
iajs-3524	119	4	to	to	PART
iajs-3524	119	5	degrade	degrade	VERB
iajs-3524	119	6	collagen	collagen	NOUN
iajs-3524	119	7	type	type	NOUN
iajs-3524	119	8	ii	ii	PROPN
iajs-3524	119	9	of	of	ADP
iajs-3524	119	10	hyaline	hyaline	ADJ
iajs-3524	119	11	cartilage	cartilage	NOUN
iajs-3524	119	12	rather	rather	ADV
iajs-3524	119	13	than	than	ADP
iajs-3524	119	14	cl-3	cl-3	PROPN
iajs-3524	119	15	,	,	PUNCT
iajs-3524	119	16	which	which	PRON
iajs-3524	119	17	degrades	degrade	VERB
iajs-3524	119	18	this	this	DET
iajs-3524	119	19	substrate	substrate	NOUN
iajs-3524	119	20	more	more	ADV
iajs-3524	119	21	efficiently	efficiently	ADV
iajs-3524	119	22	,	,	PUNCT
iajs-3524	119	23	one	one	PRON
iajs-3524	119	24	is	be	AUX
iajs-3524	119	25	tempted	tempt	VERB
iajs-3524	119	26	to	to	PART
iajs-3524	119	27	speculate	speculate	VERB
iajs-3524	119	28	that	that	SCONJ
iajs-3524	119	29	cl-3	cl-3	PRON
iajs-3524	119	30	is	be	AUX
iajs-3524	119	31	an	an	DET
iajs-3524	119	32	essential	essential	ADJ
iajs-3524	119	33	component	component	NOUN
iajs-3524	119	34	of	of	ADP
iajs-3524	119	35	the	the	DET
iajs-3524	119	36	cellular	cellular	ADJ
iajs-3524	119	37	machinery	machinery	NOUN
iajs-3524	119	38	that	that	PRON
iajs-3524	119	39	is	be	AUX
iajs-3524	119	40	responsible	responsible	ADJ
iajs-3524	119	41	for	for	ADP
iajs-3524	119	42	the	the	DET
iajs-3524	119	43	turnover	turnover	NOUN
iajs-3524	119	44	of	of	ADP
iajs-3524	119	45	articular	articular	ADJ
iajs-3524	119	46	cartilage	cartilage	NOUN
iajs-3524	119	47	.	.	PUNCT
iajs-3524	120	1	this	this	DET
iajs-3524	120	2	speculation	speculation	NOUN
iajs-3524	120	3	is	be	AUX
iajs-3524	120	4	based	base	VERB
iajs-3524	120	5	on	on	ADP
iajs-3524	120	6	the	the	DET
iajs-3524	120	7	fact	fact	NOUN
iajs-3524	120	8	that	that	SCONJ
iajs-3524	120	9	cl-3	cl-3	PRON
iajs-3524	120	10	prefers	prefer	VERB
iajs-3524	120	11	to	to	PART
iajs-3524	120	12	degrade	degrade	VERB
iajs-3524	120	13	collagen	collagen	NOUN
iajs-3524	120	14	type	type	NOUN
iajs-3524	120	15	ii	ii	PROPN
iajs-3524	120	16	of	of	ADP
iajs-3524	120	17	hyaline	hyaline	ADJ
iajs-3524	120	18	cartilage	cartilage	NOUN
iajs-3524	120	19	.	.	PUNCT
iajs-3524	121	1	this	this	DET
iajs-3524	121	2	hypothesis	hypothesis	NOUN
iajs-3524	121	3	is	be	AUX
iajs-3524	121	4	supported	support	VERB
iajs-3524	121	5	by	by	ADP
iajs-3524	121	6	the	the	DET
iajs-3524	121	7	observation	observation	NOUN
iajs-3524	121	8	that	that	PRON
iajs-3524	121	9	cl-3	cl-3	PRON
iajs-3524	121	10	shows	show	VERB
iajs-3524	121	11	a	a	DET
iajs-3524	121	12	strong	strong	ADJ
iajs-3524	121	13	preference	preference	NOUN
iajs-3524	121	14	for	for	ADP
iajs-3524	121	15	degrading	degrade	VERB
iajs-3524	121	16	type	type	NOUN
iajs-3524	121	17	ii	ii	NOUN
iajs-3524	121	18	collagen	collagen	NOUN
iajs-3524	121	19	in	in	ADP
iajs-3524	121	20	hyaline	hyaline	ADJ
iajs-3524	121	21	cartilage	cartilage	NOUN
iajs-3524	121	22	[	[	X
iajs-3524	121	23	25	25	NUM
iajs-3524	121	24	]	]	PUNCT
iajs-3524	121	25	.	.	PUNCT
iajs-3524	122	1	as	as	ADP
iajs-3524	122	2	a	a	DET
iajs-3524	122	3	direct	direct	ADJ
iajs-3524	122	4	consequence	consequence	NOUN
iajs-3524	122	5	of	of	ADP
iajs-3524	122	6	this	this	DET
iajs-3524	122	7	finding	finding	NOUN
iajs-3524	122	8	,	,	PUNCT
iajs-3524	122	9	this	this	DET
iajs-3524	122	10	molecule	molecule	NOUN
iajs-3524	122	11	would	would	AUX
iajs-3524	122	12	subsequently	subsequently	ADV
iajs-3524	122	13	be	be	AUX
iajs-3524	122	14	brought	bring	VERB
iajs-3524	122	15	to	to	ADP
iajs-3524	122	16	light	light	NOUN
iajs-3524	122	17	as	as	ADP
iajs-3524	122	18	a	a	DET
iajs-3524	122	19	potential	potential	ADJ
iajs-3524	122	20	therapeutic	therapeutic	ADJ
iajs-3524	122	21	target	target	NOUN
iajs-3524	122	22	for	for	ADP
iajs-3524	122	23	the	the	DET
iajs-3524	122	24	treatment	treatment	NOUN
iajs-3524	122	25	of	of	ADP
iajs-3524	122	26	cartilage	cartilage	NOUN
iajs-3524	122	27	degradation	degradation	NOUN
iajs-3524	122	28	.	.	PUNCT
iajs-3524	123	1	a	a	DET
iajs-3524	123	2	new	new	ADJ
iajs-3524	123	3	glimmer	glimmer	NOUN
iajs-3524	123	4	of	of	ADP
iajs-3524	123	5	hope	hope	NOUN
iajs-3524	123	6	for	for	ADP
iajs-3524	123	7	the	the	DET
iajs-3524	123	8	treatment	treatment	NOUN
iajs-3524	123	9	of	of	ADP
iajs-3524	123	10	oa	oa	PRON
iajs-3524	123	11	emerged	emerge	VERB
iajs-3524	123	12	not	not	PART
iajs-3524	123	13	too	too	ADV
iajs-3524	123	14	long	long	ADV
iajs-3524	123	15	ago	ago	ADV
iajs-3524	123	16	in	in	ADP
iajs-3524	123	17	the	the	DET
iajs-3524	123	18	shape	shape	NOUN
iajs-3524	123	19	of	of	ADP
iajs-3524	123	20	an	an	DET
iajs-3524	123	21	inhibition	inhibition	NOUN
iajs-3524	123	22	of	of	ADP
iajs-3524	123	23	cl-3	cl-3	NOUN
iajs-3524	123	24	,	,	PUNCT
iajs-3524	123	25	which	which	PRON
iajs-3524	123	26	was	be	AUX
iajs-3524	123	27	reported	report	VERB
iajs-3524	123	28	by	by	ADP
iajs-3524	123	29	li	li	PROPN
iajs-3524	123	30	and	and	CCONJ
iajs-3524	123	31	colleagues	colleague	NOUN
iajs-3524	123	32	[	[	X
iajs-3524	123	33	26	26	NUM
iajs-3524	123	34	]	]	PUNCT
iajs-3524	123	35	.	.	PUNCT
iajs-3524	124	1	in	in	ADP
iajs-3524	124	2	the	the	DET
iajs-3524	124	3	antibodyinduced	antibodyinduced	ADJ
iajs-3524	124	4	arthritis	arthritis	NOUN
iajs-3524	124	5	paradigm	paradigm	NOUN
iajs-3524	124	6	,	,	PUNCT
iajs-3524	124	7	the	the	DET
iajs-3524	124	8	pharmacological	pharmacological	NOUN
iajs-3524	124	9	lowering	lowering	NOUN
iajs-3524	124	10	of	of	ADP
iajs-3524	124	11	cl-3	cl-3	PRON
iajs-3524	124	12	did	do	AUX
iajs-3524	124	13	not	not	PART
iajs-3524	124	14	result	result	VERB
iajs-3524	124	15	in	in	ADP
iajs-3524	124	16	decreased	decrease	VERB
iajs-3524	124	17	arthritis	arthritis	NOUN
iajs-3524	124	18	;	;	PUNCT
iajs-3524	124	19	however	however	ADV
iajs-3524	124	20	,	,	PUNCT
iajs-3524	124	21	it	it	PRON
iajs-3524	124	22	did	do	AUX
iajs-3524	124	23	result	result	VERB
iajs-3524	124	24	in	in	ADP
iajs-3524	124	25	decreased	decrease	VERB
iajs-3524	124	26	arthritis	arthritis	NOUN
iajs-3524	124	27	in	in	ADP
iajs-3524	124	28	the	the	DET
iajs-3524	124	29	collagen	collagen	NOUN
iajs-3524	124	30	-	-	PUNCT
iajs-3524	124	31	induced	induce	VERB
iajs-3524	124	32	arthritis	arthritis	NOUN
iajs-3524	124	33	model	model	NOUN
iajs-3524	124	34	and	and	CCONJ
iajs-3524	124	35	the	the	DET
iajs-3524	124	36	severe	severe	ADJ
iajs-3524	124	37	mixed	mixed	ADJ
iajs-3524	124	38	immunodeficiency	immunodeficiency	NOUN
iajs-3524	124	39	mouse	mouse	NOUN
iajs-3524	124	40	implantation	implantation	NOUN
iajs-3524	124	41	model	model	NOUN
iajs-3524	124	42	[	[	X
iajs-3524	124	43	27	27	NUM
iajs-3524	124	44	]	]	PUNCT
iajs-3524	124	45	.	.	PUNCT
iajs-3524	125	1	recent	recent	ADJ
iajs-3524	125	2	study	study	NOUN
iajs-3524	125	3	has	have	AUX
iajs-3524	125	4	focused	focus	VERB
iajs-3524	125	5	on	on	ADP
iajs-3524	125	6	using	use	VERB
iajs-3524	125	7	a	a	DET
iajs-3524	125	8	model	model	NOUN
iajs-3524	125	9	of	of	ADP
iajs-3524	125	10	arthritis	arthritis	NOUN
iajs-3524	125	11	called	call	VERB
iajs-3524	125	12	the	the	DET
iajs-3524	125	13	k	k	NOUN
iajs-3524	125	14	/	/	SYM
iajs-3524	125	15	bxn	bxn	NOUN
iajs-3524	125	16	sera	sera	NOUN
iajs-3524	125	17	-	-	PUNCT
iajs-3524	125	18	transfer	transfer	NOUN
iajs-3524	125	19	model	model	NOUN
iajs-3524	125	20	to	to	PART
iajs-3524	125	21	explore	explore	VERB
iajs-3524	125	22	the	the	DET
iajs-3524	125	23	part	part	NOUN
iajs-3524	125	24	that	that	PRON
iajs-3524	125	25	cl-3	cl-3	PRON
iajs-3524	125	26	plays	play	VERB
iajs-3524	125	27	in	in	ADP
iajs-3524	125	28	the	the	DET
iajs-3524	125	29	illness	illness	NOUN
iajs-3524	125	30	.	.	PUNCT
iajs-3524	126	1	this	this	DET
iajs-3524	126	2	model	model	NOUN
iajs-3524	126	3	is	be	AUX
iajs-3524	126	4	known	know	VERB
iajs-3524	126	5	as	as	ADP
iajs-3524	126	6	the	the	DET
iajs-3524	126	7	k	k	NOUN
iajs-3524	126	8	/	/	SYM
iajs-3524	126	9	bxn	bxn	NOUN
iajs-3524	126	10	sera	sera	NOUN
iajs-3524	126	11	-	-	PUNCT
iajs-3524	126	12	transfer	transfer	NOUN
iajs-3524	126	13	model	model	NOUN
iajs-3524	126	14	.	.	PUNCT
iajs-3524	127	1	in	in	ADP
iajs-3524	127	2	the	the	DET
iajs-3524	127	3	k	k	NOUN
iajs-3524	127	4	/	/	SYM
iajs-3524	127	5	bxn	bxn	NOUN
iajs-3524	127	6	paradigm	paradigm	NOUN
iajs-3524	127	7	,	,	PUNCT
iajs-3524	127	8	arthritis	arthritis	NOUN
iajs-3524	127	9	develops	develop	VERB
iajs-3524	127	10	on	on	ADP
iajs-3524	127	11	its	its	PRON
iajs-3524	127	12	own	own	ADJ
iajs-3524	127	13	in	in	ADP
iajs-3524	127	14	mice	mouse	NOUN
iajs-3524	127	15	that	that	PRON
iajs-3524	127	16	express	express	VERB
iajs-3524	127	17	both	both	CCONJ
iajs-3524	127	18	the	the	DET
iajs-3524	127	19	transgene	transgene	NOUN
iajs-3524	127	20	-	-	PUNCT
iajs-3524	127	21	encoded	encode	VERB
iajs-3524	127	22	krn	krn	PROPN
iajs-3524	127	23	t	t	PROPN
iajs-3524	127	24	-	-	PUNCT
iajs-3524	127	25	cell	cell	NOUN
iajs-3524	127	26	receptor	receptor	NOUN
iajs-3524	127	27	and	and	CCONJ
iajs-3524	127	28	the	the	DET
iajs-3524	127	29	iag7	iag7	PROPN
iajs-3524	127	30	major	major	ADJ
iajs-3524	127	31	histocompatibility	histocompatibility	NOUN
iajs-3524	127	32	complex	complex	ADJ
iajs-3524	127	33	class	class	NOUN
iajs-3524	127	34	ii	ii	NOUN
iajs-3524	127	35	allele	allele	NOUN
iajs-3524	128	1	[	[	X
iajs-3524	128	2	28,29	28,29	X
iajs-3524	128	3	]	]	PUNCT
iajs-3524	128	4	.	.	PUNCT
iajs-3524	129	1	this	this	PRON
iajs-3524	129	2	occurs	occur	VERB
iajs-3524	129	3	because	because	SCONJ
iajs-3524	129	4	the	the	DET
iajs-3524	129	5	krn	krn	PROPN
iajs-3524	129	6	t	t	PROPN
iajs-3524	129	7	-	-	PUNCT
iajs-3524	129	8	cell	cell	NOUN
iajs-3524	129	9	receptor	receptor	NOUN
iajs-3524	129	10	acts	act	VERB
iajs-3524	129	11	as	as	ADP
iajs-3524	129	12	a	a	DET
iajs-3524	129	13	trigger	trigger	NOUN
iajs-3524	129	14	for	for	ADP
iajs-3524	129	15	the	the	DET
iajs-3524	129	16	development	development	NOUN
iajs-3524	129	17	of	of	ADP
iajs-3524	129	18	arthritis	arthritis	NOUN
iajs-3524	129	19	in	in	ADP
iajs-3524	129	20	these	these	DET
iajs-3524	129	21	animals	animal	NOUN
iajs-3524	129	22	.	.	PUNCT
iajs-3524	130	1	this	this	PRON
iajs-3524	130	2	is	be	AUX
iajs-3524	130	3	because	because	SCONJ
iajs-3524	130	4	it	it	PRON
iajs-3524	130	5	is	be	AUX
iajs-3524	130	6	believed	believe	VERB
iajs-3524	130	7	that	that	SCONJ
iajs-3524	130	8	the	the	DET
iajs-3524	130	9	krn	krn	PROPN
iajs-3524	130	10	t	t	PROPN
iajs-3524	130	11	-	-	PUNCT
iajs-3524	130	12	cell	cell	NOUN
iajs-3524	130	13	receptor	receptor	NOUN
iajs-3524	130	14	is	be	AUX
iajs-3524	130	15	involved	involve	VERB
iajs-3524	130	16	in	in	ADP
iajs-3524	130	17	the	the	DET
iajs-3524	130	18	development	development	NOUN
iajs-3524	130	19	of	of	ADP
iajs-3524	130	20	arthritis	arthritis	NOUN
iajs-3524	130	21	.	.	PUNCT
iajs-3524	131	1	this	this	PRON
iajs-3524	131	2	is	be	AUX
iajs-3524	131	3	because	because	SCONJ
iajs-3524	131	4	the	the	DET
iajs-3524	131	5	krn	krn	PROPN
iajs-3524	131	6	t	t	PROPN
iajs-3524	131	7	-	-	PUNCT
iajs-3524	131	8	cell	cell	NOUN
iajs-3524	131	9	receptor	receptor	NOUN
iajs-3524	131	10	is	be	AUX
iajs-3524	131	11	important	important	ADJ
iajs-3524	131	12	for	for	ADP
iajs-3524	131	13	the	the	DET
iajs-3524	131	14	development	development	NOUN
iajs-3524	131	15	of	of	ADP
iajs-3524	131	16	arthritis	arthritis	NOUN
iajs-3524	131	17	.	.	PUNCT
iajs-3524	132	1	animals	animal	NOUN
iajs-3524	132	2	that	that	PRON
iajs-3524	132	3	are	be	AUX
iajs-3524	132	4	deficient	deficient	ADJ
iajs-3524	132	5	in	in	ADP
iajs-3524	132	6	cl-3	cl-3	PUNCT
iajs-3524	132	7	have	have	VERB
iajs-3524	132	8	a	a	DET
iajs-3524	132	9	reduced	reduced	ADJ
iajs-3524	132	10	risk	risk	NOUN
iajs-3524	132	11	of	of	ADP
iajs-3524	132	12	inflammatory	inflammatory	ADJ
iajs-3524	132	13	conditions	condition	NOUN
iajs-3524	132	14	and	and	CCONJ
iajs-3524	132	15	joint	joint	ADJ
iajs-3524	132	16	damage	damage	NOUN
iajs-3524	132	17	[	[	X
iajs-3524	132	18	30	30	NUM
iajs-3524	132	19	,	,	PUNCT
iajs-3524	132	20	31	31	NUM
iajs-3524	132	21	]	]	PUNCT
iajs-3524	132	22	.	.	PUNCT
iajs-3524	133	1	this	this	PRON
iajs-3524	133	2	occurs	occur	VERB
iajs-3524	133	3	as	as	ADP
iajs-3524	133	4	a	a	DET
iajs-3524	133	5	result	result	NOUN
iajs-3524	133	6	of	of	ADP
iajs-3524	133	7	an	an	DET
iajs-3524	133	8	increase	increase	NOUN
iajs-3524	133	9	in	in	ADP
iajs-3524	133	10	the	the	DET
iajs-3524	133	11	expression	expression	NOUN
iajs-3524	133	12	of	of	ADP
iajs-3524	133	13	cl-3	cl-3	NOUN
iajs-3524	133	14	in	in	ADP
iajs-3524	133	15	c57bl/6	c57bl/6	NOUN
iajs-3524	133	16	mice	mouse	NOUN
iajs-3524	133	17	throughout	throughout	ADP
iajs-3524	133	18	the	the	DET
iajs-3524	133	19	k	k	NOUN
iajs-3524	133	20	/	/	SYM
iajs-3524	133	21	bxn	bxn	VERB
iajs-3524	133	22	serum	serum	NOUN
iajs-3524	133	23	-	-	PUNCT
iajs-3524	133	24	induced	induce	VERB
iajs-3524	133	25	arthritis	arthritis	NOUN
iajs-3524	133	26	.	.	PUNCT
iajs-3524	134	1	there	there	PRON
iajs-3524	134	2	is	be	VERB
iajs-3524	134	3	an	an	DET
iajs-3524	134	4	increase	increase	NOUN
iajs-3524	134	5	in	in	ADP
iajs-3524	134	6	the	the	DET
iajs-3524	134	7	expression	expression	NOUN
iajs-3524	134	8	of	of	ADP
iajs-3524	134	9	cl-3	cl-3	NOUN
iajs-3524	134	10	as	as	ADP
iajs-3524	134	11	the	the	DET
iajs-3524	134	12	k	k	NOUN
iajs-3524	134	13	/	/	SYM
iajs-3524	134	14	bxn	bxn	VERB
iajs-3524	134	15	serum	serum	NOUN
iajs-3524	134	16	-	-	PUNCT
iajs-3524	134	17	induced	induce	VERB
iajs-3524	134	18	arthritis	arthritis	NOUN
iajs-3524	134	19	progresses	progress	NOUN
iajs-3524	134	20	in	in	ADP
iajs-3524	134	21	c57bl/6	c57bl/6	NOUN
iajs-3524	134	22	mice	mouse	NOUN
iajs-3524	134	23	.	.	PUNCT
iajs-3524	135	1	this	this	DET
iajs-3524	135	2	increase	increase	NOUN
iajs-3524	135	3	in	in	ADP
iajs-3524	135	4	expression	expression	NOUN
iajs-3524	135	5	may	may	AUX
iajs-3524	135	6	be	be	AUX
iajs-3524	135	7	seen	see	VERB
iajs-3524	135	8	throughout	throughout	ADP
iajs-3524	135	9	the	the	DET
iajs-3524	135	10	arthritis	arthritis	NOUN
iajs-3524	135	11	.	.	PUNCT
iajs-3524	136	1	collagenase3	collagenase3	PROPN
iajs-3524	136	2	is	be	AUX
iajs-3524	136	3	the	the	DET
iajs-3524	136	4	most	most	ADV
iajs-3524	136	5	effective	effective	ADJ
iajs-3524	136	6	collagenase	collagenase	NOUN
iajs-3524	136	7	when	when	SCONJ
iajs-3524	136	8	it	it	PRON
iajs-3524	136	9	comes	come	VERB
iajs-3524	136	10	to	to	ADP
iajs-3524	136	11	type	type	NOUN
iajs-3524	136	12	ii	ii	PROPN
iajs-3524	136	13	collagen	collagen	NOUN
iajs-3524	136	14	,	,	PUNCT
iajs-3524	136	15	which	which	PRON
iajs-3524	136	16	is	be	AUX
iajs-3524	136	17	the	the	DET
iajs-3524	136	18	primary	primary	ADJ
iajs-3524	136	19	structural	structural	ADJ
iajs-3524	136	20	collagen	collagen	NOUN
iajs-3524	136	21	that	that	PRON
iajs-3524	136	22	is	be	AUX
iajs-3524	136	23	present	present	ADJ
iajs-3524	136	24	in	in	ADP
iajs-3524	136	25	articular	articular	ADJ
iajs-3524	136	26	cartilage	cartilage	NOUN
iajs-3524	136	27	.	.	PUNCT
iajs-3524	137	1	this	this	PRON
iajs-3524	137	2	is	be	AUX
iajs-3524	137	3	the	the	DET
iajs-3524	137	4	case	case	NOUN
iajs-3524	137	5	since	since	SCONJ
iajs-3524	137	6	type	type	NOUN
iajs-3524	137	7	ii	ii	PROPN
iajs-3524	137	8	collagen	collagen	NOUN
iajs-3524	137	9	is	be	AUX
iajs-3524	137	10	the	the	DET
iajs-3524	137	11	primary	primary	ADJ
iajs-3524	137	12	constituent	constituent	NOUN
iajs-3524	137	13	of	of	ADP
iajs-3524	137	14	articular	articular	ADJ
iajs-3524	137	15	cartilage	cartilage	NOUN
iajs-3524	137	16	.	.	PUNCT
iajs-3524	138	1	a	a	DET
iajs-3524	138	2	diverse	diverse	ADJ
iajs-3524	138	3	network	network	NOUN
iajs-3524	138	4	of	of	ADP
iajs-3524	138	5	signal	signal	ADJ
iajs-3524	138	6	transduction	transduction	NOUN
iajs-3524	138	7	pathways	pathway	NOUN
iajs-3524	138	8	is	be	AUX
iajs-3524	138	9	activated	activate	VERB
iajs-3524	138	10	when	when	SCONJ
iajs-3524	138	11	powerful	powerful	ADJ
iajs-3524	138	12	pro	pro	ADJ
iajs-3524	138	13	-	-	ADJ
iajs-3524	138	14	inflammatory	inflammatory	ADJ
iajs-3524	138	15	stimuli	stimulus	NOUN
iajs-3524	138	16	such	such	ADJ
iajs-3524	138	17	as	as	ADP
iajs-3524	138	18	il-1	il-1	NUM
iajs-3524	138	19	and	and	CCONJ
iajs-3524	138	20	osm	osm	PROPN
iajs-3524	138	21	are	be	AUX
iajs-3524	138	22	present	present	ADJ
iajs-3524	139	1	[	[	X
iajs-3524	139	2	32	32	NUM
iajs-3524	139	3	]	]	PUNCT
iajs-3524	139	4	.	.	PUNCT
iajs-3524	140	1	research	research	NOUN
iajs-3524	140	2	has	have	AUX
iajs-3524	140	3	demonstrated	demonstrate	VERB
iajs-3524	140	4	that	that	SCONJ
iajs-3524	140	5	a	a	DET
iajs-3524	140	6	broad	broad	ADJ
iajs-3524	140	7	array	array	NOUN
iajs-3524	140	8	of	of	ADP
iajs-3524	140	9	pro	pro	ADJ
iajs-3524	140	10	-	-	ADJ
iajs-3524	140	11	inflammatory	inflammatory	ADJ
iajs-3524	140	12	stimuli	stimulus	NOUN
iajs-3524	140	13	all	all	PRON
iajs-3524	140	14	use	use	VERB
iajs-3524	140	15	the	the	DET
iajs-3524	140	16	same	same	ADJ
iajs-3524	140	17	pathways	pathway	NOUN
iajs-3524	140	18	to	to	PART
iajs-3524	140	19	cause	cause	VERB
iajs-3524	140	20	inflammation	inflammation	NOUN
iajs-3524	140	21	.	.	PUNCT
iajs-3524	141	1	these	these	DET
iajs-3524	141	2	routes	route	NOUN
iajs-3524	141	3	,	,	PUNCT
iajs-3524	141	4	when	when	SCONJ
iajs-3524	141	5	activated	activate	VERB
iajs-3524	141	6	in	in	ADP
iajs-3524	141	7	conjunction	conjunction	NOUN
iajs-3524	141	8	with	with	ADP
iajs-3524	141	9	one	one	NUM
iajs-3524	141	10	another	another	DET
iajs-3524	141	11	,	,	PUNCT
iajs-3524	141	12	have	have	VERB
iajs-3524	141	13	a	a	DET
iajs-3524	141	14	synergistic	synergistic	ADJ
iajs-3524	141	15	effect	effect	NOUN
iajs-3524	141	16	that	that	SCONJ
iajs-3524	141	17	,	,	PUNCT
iajs-3524	141	18	when	when	SCONJ
iajs-3524	141	19	applied	apply	VERB
iajs-3524	141	20	to	to	ADP
iajs-3524	141	21	chondrocytes	chondrocyte	NOUN
iajs-3524	141	22	,	,	PUNCT
iajs-3524	141	23	significantly	significantly	ADV
iajs-3524	141	24	boosts	boost	VERB
iajs-3524	141	25	the	the	DET
iajs-3524	141	26	synthesis	synthesis	NOUN
iajs-3524	141	27	of	of	ADP
iajs-3524	141	28	collagenase-3	collagenase-3	NUM
iajs-3524	141	29	[	[	X
iajs-3524	141	30	33	33	NUM
iajs-3524	141	31	]	]	PUNCT
iajs-3524	141	32	.	.	PUNCT
iajs-3524	142	1	although	although	SCONJ
iajs-3524	142	2	we	we	PRON
iajs-3524	142	3	have	have	AUX
iajs-3524	142	4	just	just	ADV
iajs-3524	142	5	recently	recently	ADV
iajs-3524	142	6	reported	report	VERB
iajs-3524	142	7	a	a	DET
iajs-3524	142	8	role	role	NOUN
iajs-3524	142	9	for	for	ADP
iajs-3524	142	10	the	the	DET
iajs-3524	142	11	ap-1	ap-1	ADV
iajs-3524	142	12	-	-	PUNCT
iajs-3524	142	13	binding	bind	VERB
iajs-3524	142	14	factor	factor	NOUN
iajs-3524	142	15	activating	activate	VERB
iajs-3524	142	16	transcription	transcription	NOUN
iajs-3524	142	17	factor	factor	NOUN
iajs-3524	142	18	3	3	NUM
iajs-3524	142	19	(	(	PUNCT
iajs-3524	142	20	atf3	atf3	NOUN
iajs-3524	142	21	)	)	PUNCT
iajs-3524	142	22	in	in	ADP
iajs-3524	142	23	selectively	selectively	ADV
iajs-3524	142	24	mediating	mediate	VERB
iajs-3524	142	25	cl-3	cl-3	NOUN
iajs-3524	142	26	expression	expression	NOUN
iajs-3524	142	27	that	that	PRON
iajs-3524	142	28	was	be	AUX
iajs-3524	142	29	nonetheless	nonetheless	ADV
iajs-3524	142	30	dependent	dependent	ADJ
iajs-3524	142	31	on	on	ADP
iajs-3524	142	32	ap-1	ap-1	X
iajs-3524	143	1	[	[	X
iajs-3524	143	2	34	34	NUM
iajs-3524	143	3	]	]	PUNCT
iajs-3524	143	4	.	.	PUNCT
iajs-3524	144	1	it	it	PRON
iajs-3524	144	2	is	be	AUX
iajs-3524	144	3	essential	essential	ADJ
iajs-3524	144	4	to	to	PART
iajs-3524	144	5	keep	keep	VERB
iajs-3524	144	6	in	in	ADP
iajs-3524	144	7	mind	mind	NOUN
iajs-3524	144	8	that	that	SCONJ
iajs-3524	144	9	the	the	DET
iajs-3524	144	10	cfos	cfos	PROPN
iajs-3524	144	11	/	/	SYM
iajs-3524	144	12	cjun	cjun	NOUN
iajs-3524	144	13	activator	activator	NOUN
iajs-3524	144	14	protein-1	protein-1	PROPN
iajs-3524	144	15	(	(	PUNCT
iajs-3524	144	16	ap-1	ap-1	NOUN
iajs-3524	144	17	)	)	PUNCT
iajs-3524	144	18	transcription	transcription	NOUN
iajs-3524	144	19	factor	factor	NOUN
iajs-3524	144	20	complex	complex	NOUN
iajs-3524	144	21	is	be	AUX
iajs-3524	144	22	required	require	VERB
iajs-3524	144	23	for	for	ADP
iajs-3524	144	24	the	the	DET
iajs-3524	144	25	expression	expression	NOUN
iajs-3524	144	26	of	of	ADP
iajs-3524	144	27	cl-3	cl-3	NOUN
iajs-3524	144	28	.	.	PUNCT
iajs-3524	145	1	in	in	ADP
iajs-3524	145	2	addition	addition	NOUN
iajs-3524	145	3	,	,	PUNCT
iajs-3524	145	4	we	we	PRON
iajs-3524	145	5	have	have	AUX
iajs-3524	145	6	shown	show	VERB
iajs-3524	145	7	in	in	ADP
iajs-3524	145	8	the	the	DET
iajs-3524	145	9	past	past	NOUN
iajs-3524	145	10	that	that	SCONJ
iajs-3524	145	11	the	the	DET
iajs-3524	145	12	signaling	signal	VERB
iajs-3524	145	13	pathways	pathway	NOUN
iajs-3524	145	14	for	for	ADP
iajs-3524	145	15	signal	signal	ADJ
iajs-3524	145	16	transducer	transducer	NOUN
iajs-3524	145	17	and	and	CCONJ
iajs-3524	145	18	activator	activator	NOUN
iajs-3524	145	19	of	of	ADP
iajs-3524	145	20	transcription	transcription	NOUN
iajs-3524	145	21	(	(	PUNCT
iajs-3524	145	22	stat)3	stat)3	NOUN
iajs-3524	145	23	,	,	PUNCT
iajs-3524	145	24	phosphatidylinositol-3	phosphatidylinositol-3	NUM
iajs-3524	145	25	'	'	PUNCT
iajs-3524	145	26	kinase	kinase	NOUN
iajs-3524	145	27	(	(	PUNCT
iajs-3524	145	28	pi3k	pi3k	PROPN
iajs-3524	145	29	/	/	SYM
iajs-3524	145	30	akt	akt	PROPN
iajs-3524	145	31	)	)	PUNCT
iajs-3524	145	32	,	,	PUNCT
iajs-3524	145	33	and	and	CCONJ
iajs-3524	145	34	protein	protein	NOUN
iajs-3524	145	35	kinase	kinase	PROPN
iajs-3524	145	36	c	c	PROPN
iajs-3524	145	37	(	(	PUNCT
iajs-3524	145	38	pkc	pkc	NOUN
iajs-3524	145	39	)	)	PUNCT
iajs-3524	145	40	are	be	AUX
iajs-3524	145	41	of	of	ADP
iajs-3524	145	42	the	the	DET
iajs-3524	145	43	utmost	utmost	ADJ
iajs-3524	145	44	significance	significance	NOUN
iajs-3524	145	45	[	[	X
iajs-3524	145	46	35	35	NUM
iajs-3524	145	47	]	]	PUNCT
iajs-3524	145	48	.	.	PUNCT
iajs-3524	146	1	however	however	ADV
iajs-3524	146	2	,	,	PUNCT
iajs-3524	146	3	the	the	DET
iajs-3524	146	4	identification	identification	NOUN
iajs-3524	146	5	of	of	ADP
iajs-3524	146	6	the	the	DET
iajs-3524	146	7	downstream	downstream	ADJ
iajs-3524	146	8	signaling	signal	VERB
iajs-3524	146	9	components	component	NOUN
iajs-3524	146	10	that	that	SCONJ
iajs-3524	146	11	it	it	PRON
iajs-3524	146	12	influences	influence	VERB
iajs-3524	146	13	is	be	AUX
iajs-3524	146	14	unknown	unknown	ADJ
iajs-3524	146	15	,	,	PUNCT
iajs-3524	146	16	as	as	SCONJ
iajs-3524	146	17	are	be	AUX
iajs-3524	146	18	the	the	DET
iajs-3524	146	19	likely	likely	ADJ
iajs-3524	146	20	sites	site	NOUN
iajs-3524	146	21	of	of	ADP
iajs-3524	146	22	cross	cross	NOUN
iajs-3524	146	23	-	-	NOUN
iajs-3524	146	24	talk	talk	NOUN
iajs-3524	146	25	.	.	PUNCT
iajs-3524	147	1	although	although	SCONJ
iajs-3524	147	2	it	it	PRON
iajs-3524	147	3	has	have	VERB
iajs-3524	147	4	ihjpas	ihjpa	NOUN
iajs-3524	147	5	.	.	PUNCT
iajs-3524	148	1	2024	2024	NUM
iajs-3524	148	2	,	,	PUNCT
iajs-3524	148	3	37(4	37(4	X
iajs-3524	148	4	)	)	PUNCT
iajs-3524	148	5	291	291	NUM
iajs-3524	148	6	been	be	AUX
iajs-3524	148	7	shown	show	VERB
iajs-3524	148	8	that	that	SCONJ
iajs-3524	148	9	the	the	DET
iajs-3524	148	10	atypical	atypical	ADJ
iajs-3524	148	11	pkc	pkc	PROPN
iajs-3524	148	12	isoform	isoform	NOUN
iajs-3524	148	13	pkc	pkc	PROPN
iajs-3524	148	14	may	may	AUX
iajs-3524	148	15	alter	alter	VERB
iajs-3524	148	16	the	the	DET
iajs-3524	148	17	induction	induction	NOUN
iajs-3524	148	18	of	of	ADP
iajs-3524	148	19	cl-3	cl-3	NOUN
iajs-3524	148	20	in	in	ADP
iajs-3524	148	21	response	response	NOUN
iajs-3524	148	22	to	to	ADP
iajs-3524	148	23	il-1+osm	il-1+osm	NOUN
iajs-3524	148	24	stimulation	stimulation	NOUN
iajs-3524	148	25	,	,	PUNCT
iajs-3524	148	26	it	it	PRON
iajs-3524	148	27	is	be	AUX
iajs-3524	148	28	unclear	unclear	ADJ
iajs-3524	148	29	which	which	DET
iajs-3524	148	30	components	component	NOUN
iajs-3524	148	31	of	of	ADP
iajs-3524	148	32	the	the	DET
iajs-3524	148	33	signaling	signal	VERB
iajs-3524	148	34	pathway	pathway	NOUN
iajs-3524	148	35	it	it	PRON
iajs-3524	148	36	impacts	impact	VERB
iajs-3524	148	37	.	.	PUNCT
iajs-3524	149	1	this	this	PRON
iajs-3524	149	2	is	be	AUX
iajs-3524	149	3	even	even	ADV
iajs-3524	149	4	though	though	SCONJ
iajs-3524	149	5	it	it	PRON
iajs-3524	149	6	has	have	AUX
iajs-3524	149	7	been	be	AUX
iajs-3524	149	8	shown	show	VERB
iajs-3524	149	9	that	that	SCONJ
iajs-3524	149	10	the	the	DET
iajs-3524	149	11	identification	identification	NOUN
iajs-3524	149	12	of	of	ADP
iajs-3524	149	13	the	the	DET
iajs-3524	149	14	downstream	downstream	ADJ
iajs-3524	149	15	signaling	signal	VERB
iajs-3524	149	16	components	component	NOUN
iajs-3524	149	17	that	that	SCONJ
iajs-3524	149	18	it	it	PRON
iajs-3524	149	19	affects	affect	VERB
iajs-3524	149	20	is	be	AUX
iajs-3524	149	21	unknown	unknown	ADJ
iajs-3524	149	22	,	,	PUNCT
iajs-3524	149	23	as	as	SCONJ
iajs-3524	149	24	proven	prove	VERB
iajs-3524	149	25	by	by	ADP
iajs-3524	149	26	the	the	DET
iajs-3524	149	27	fact	fact	NOUN
iajs-3524	149	28	that	that	SCONJ
iajs-3524	149	29	this	this	PRON
iajs-3524	149	30	is	be	AUX
iajs-3524	149	31	the	the	DET
iajs-3524	149	32	case	case	NOUN
iajs-3524	149	33	[	[	X
iajs-3524	149	34	36	36	NUM
iajs-3524	149	35	]	]	PUNCT
iajs-3524	149	36	.	.	PUNCT
iajs-3524	150	1	in	in	ADP
iajs-3524	150	2	table	table	NOUN
iajs-3524	150	3	3	3	NUM
iajs-3524	150	4	,	,	PUNCT
iajs-3524	150	5	the	the	DET
iajs-3524	150	6	findings	finding	NOUN
iajs-3524	150	7	of	of	ADP
iajs-3524	150	8	an	an	DET
iajs-3524	150	9	analysis	analysis	NOUN
iajs-3524	150	10	that	that	PRON
iajs-3524	150	11	was	be	AUX
iajs-3524	150	12	carried	carry	VERB
iajs-3524	150	13	out	out	ADP
iajs-3524	150	14	on	on	ADP
iajs-3524	150	15	each	each	PRON
iajs-3524	150	16	of	of	ADP
iajs-3524	150	17	the	the	DET
iajs-3524	150	18	groups	group	NOUN
iajs-3524	150	19	that	that	PRON
iajs-3524	150	20	were	be	AUX
iajs-3524	150	21	examined	examine	VERB
iajs-3524	150	22	to	to	PART
iajs-3524	150	23	estimate	estimate	VERB
iajs-3524	150	24	the	the	DET
iajs-3524	150	25	coefficient	coefficient	NOUN
iajs-3524	150	26	of	of	ADP
iajs-3524	150	27	association	association	NOUN
iajs-3524	150	28	(	(	PUNCT
iajs-3524	150	29	r	r	NOUN
iajs-3524	150	30	)	)	PUNCT
iajs-3524	150	31	between	between	ADP
iajs-3524	150	32	cl-3	cl-3	NOUN
iajs-3524	150	33	and	and	CCONJ
iajs-3524	150	34	the	the	DET
iajs-3524	150	35	other	other	ADJ
iajs-3524	150	36	parameters	parameter	NOUN
iajs-3524	150	37	are	be	AUX
iajs-3524	150	38	shown	show	VERB
iajs-3524	150	39	.	.	PUNCT
iajs-3524	151	1	this	this	DET
iajs-3524	151	2	analysis	analysis	NOUN
iajs-3524	151	3	was	be	AUX
iajs-3524	151	4	carried	carry	VERB
iajs-3524	151	5	out	out	ADP
iajs-3524	151	6	to	to	PART
iajs-3524	151	7	identify	identify	VERB
iajs-3524	151	8	the	the	DET
iajs-3524	151	9	relationship	relationship	NOUN
iajs-3524	151	10	between	between	ADP
iajs-3524	151	11	cl-3	cl-3	NOUN
iajs-3524	151	12	and	and	CCONJ
iajs-3524	151	13	the	the	DET
iajs-3524	151	14	other	other	ADJ
iajs-3524	151	15	parameters	parameter	NOUN
iajs-3524	151	16	.	.	PUNCT
iajs-3524	152	1	table	table	NOUN
iajs-3524	152	2	3	3	NUM
iajs-3524	152	3	.	.	X
iajs-3524	152	4	relationship	relationship	NOUN
iajs-3524	152	5	coefficient	coefficient	NOUN
iajs-3524	152	6	between	between	ADP
iajs-3524	152	7	cl-3	cl-3	NOUN
iajs-3524	152	8	and	and	CCONJ
iajs-3524	152	9	other	other	ADJ
iajs-3524	152	10	parameters	parameter	NOUN
iajs-3524	152	11	for	for	ADP
iajs-3524	152	12	the	the	DET
iajs-3524	152	13	studied	study	VERB
iajs-3524	152	14	groups	group	NOUN
iajs-3524	152	15	.	.	PUNCT
iajs-3524	153	1	parameters	parameter	NOUN
iajs-3524	153	2	relationship	relationship	VERB
iajs-3524	153	3	coefficient	coefficient	NOUN
iajs-3524	153	4	-	-	PUNCT
iajs-3524	153	5	r	r	NOUN
iajs-3524	153	6	g1	g1	PROPN
iajs-3524	153	7	g2	g2	PROPN
iajs-3524	153	8	g3	g3	PROPN
iajs-3524	153	9	rf	rf	PRON
iajs-3524	153	10	(	(	PUNCT
iajs-3524	153	11	iu	iu	NOUN
iajs-3524	153	12	/	/	SYM
iajs-3524	153	13	ml	ml	NOUN
iajs-3524	153	14	)	)	PUNCT
iajs-3524	153	15	0.04	0.04	NUM
iajs-3524	153	16	-0.11	-0.11	NUM
iajs-3524	153	17	0.12	0.12	NUM
iajs-3524	153	18	esr	esr	PROPN
iajs-3524	153	19	(	(	PUNCT
iajs-3524	153	20	mm	mm	PROPN
iajs-3524	153	21	/	/	SYM
iajs-3524	153	22	hr	hr	NOUN
iajs-3524	153	23	)	)	PUNCT
iajs-3524	153	24	0.33	0.33	NUM
iajs-3524	153	25	-0.11	-0.11	NUM
iajs-3524	153	26	0.19	0.19	NUM
iajs-3524	153	27	hba1c	hba1c	PROPN
iajs-3524	153	28	(	(	PUNCT
iajs-3524	153	29	%	%	NOUN
iajs-3524	153	30	)	)	PUNCT
iajs-3524	153	31	0.02	0.02	NUM
iajs-3524	153	32	0.22	0.22	NUM
iajs-3524	153	33	0.33	0.33	NUM
iajs-3524	153	34	anti	anti	ADJ
iajs-3524	153	35	-	-	ADJ
iajs-3524	153	36	ccp	ccp	ADJ
iajs-3524	153	37	(	(	PUNCT
iajs-3524	153	38	u	u	NOUN
iajs-3524	153	39	/	/	SYM
iajs-3524	153	40	ml	ml	NOUN
iajs-3524	153	41	)	)	PUNCT
iajs-3524	153	42	-0.07	-0.07	NUM
iajs-3524	153	43	0.35	0.35	NUM
iajs-3524	153	44	0.17	0.17	NUM
iajs-3524	153	45	the	the	DET
iajs-3524	153	46	present	present	ADJ
iajs-3524	153	47	study	study	NOUN
iajs-3524	153	48	showed	show	VERB
iajs-3524	153	49	a	a	DET
iajs-3524	153	50	negative	negative	ADJ
iajs-3524	153	51	relationship	relationship	NOUN
iajs-3524	153	52	between	between	ADP
iajs-3524	153	53	cl-3	cl-3	NOUN
iajs-3524	153	54	levels	level	NOUN
iajs-3524	153	55	and	and	CCONJ
iajs-3524	153	56	rf	rf	VERB
iajs-3524	153	57	in	in	ADP
iajs-3524	153	58	g2	g2	PROPN
iajs-3524	153	59	(	(	PUNCT
iajs-3524	153	60	r2=	r2=	PROPN
iajs-3524	153	61	-0.11	-0.11	NUM
iajs-3524	153	62	)	)	PUNCT
iajs-3524	153	63	.	.	PUNCT
iajs-3524	154	1	a	a	DET
iajs-3524	154	2	positive	positive	ADJ
iajs-3524	154	3	relationship	relationship	NOUN
iajs-3524	154	4	was	be	AUX
iajs-3524	154	5	found	find	VERB
iajs-3524	154	6	in	in	ADP
iajs-3524	154	7	g1	g1	PROPN
iajs-3524	154	8	and	and	CCONJ
iajs-3524	154	9	g3	g3	PROPN
iajs-3524	154	10	(	(	PUNCT
iajs-3524	154	11	r1=0.04	r1=0.04	PROPN
iajs-3524	154	12	,	,	PUNCT
iajs-3524	154	13	r3=	r3=	NOUN
iajs-3524	154	14	0.12	0.12	NUM
iajs-3524	154	15	)	)	PUNCT
iajs-3524	154	16	as	as	SCONJ
iajs-3524	154	17	shown	show	VERB
iajs-3524	154	18	in	in	ADP
iajs-3524	154	19	figure	figure	NOUN
iajs-3524	154	20	1	1	NUM
iajs-3524	154	21	.	.	PUNCT
iajs-3524	155	1	collagenase-3	collagenase-3	NUM
iajs-3524	155	2	levels	level	NOUN
iajs-3524	155	3	and	and	CCONJ
iajs-3524	155	4	esr	esr	PROPN
iajs-3524	155	5	in	in	ADP
iajs-3524	155	6	g2	g2	PROPN
iajs-3524	155	7	had	have	VERB
iajs-3524	155	8	a	a	DET
iajs-3524	155	9	poor	poor	ADJ
iajs-3524	155	10	connection	connection	NOUN
iajs-3524	155	11	,	,	PUNCT
iajs-3524	155	12	according	accord	VERB
iajs-3524	155	13	to	to	ADP
iajs-3524	155	14	the	the	DET
iajs-3524	155	15	research	research	NOUN
iajs-3524	155	16	(	(	PUNCT
iajs-3524	155	17	r2=0.11	r2=0.11	NOUN
iajs-3524	155	18	)	)	PUNCT
iajs-3524	155	19	.	.	PUNCT
iajs-3524	156	1	while	while	SCONJ
iajs-3524	156	2	g1	g1	PROPN
iajs-3524	156	3	and	and	CCONJ
iajs-3524	156	4	g3	g3	PROPN
iajs-3524	156	5	showed	show	VERB
iajs-3524	156	6	a	a	DET
iajs-3524	156	7	positive	positive	ADJ
iajs-3524	156	8	association	association	NOUN
iajs-3524	156	9	(	(	PUNCT
iajs-3524	156	10	r1=0.33	r1=0.33	NOUN
iajs-3524	156	11	,	,	PUNCT
iajs-3524	156	12	r3=0.19	r3=0.19	NOUN
iajs-3524	156	13	)	)	PUNCT
iajs-3524	156	14	,	,	PUNCT
iajs-3524	156	15	which	which	PRON
iajs-3524	156	16	is	be	AUX
iajs-3524	156	17	seen	see	VERB
iajs-3524	156	18	in	in	ADP
iajs-3524	156	19	figure	figure	NOUN
iajs-3524	156	20	2	2	NUM
iajs-3524	156	21	.	.	PUNCT
iajs-3524	156	22	figure	figure	NOUN
iajs-3524	156	23	1	1	NUM
iajs-3524	156	24	.	.	PUNCT
iajs-3524	156	25	relationship	relationship	NOUN
iajs-3524	156	26	between	between	ADP
iajs-3524	156	27	collagenase-3	collagenase-3	PROPN
iajs-3524	156	28	and	and	CCONJ
iajs-3524	156	29	rf	rf	PROPN
iajs-3524	156	30	.	.	PROPN
iajs-3524	156	31	study	study	NOUN
iajs-3524	156	32	revealed	reveal	VERB
iajs-3524	156	33	a	a	DET
iajs-3524	156	34	positive	positive	ADJ
iajs-3524	156	35	relationship	relationship	NOUN
iajs-3524	156	36	between	between	ADP
iajs-3524	156	37	cl-3	cl-3	NOUN
iajs-3524	156	38	levels	level	NOUN
iajs-3524	156	39	and	and	CCONJ
iajs-3524	156	40	hba1c	hba1c	PROPN
iajs-3524	156	41	in	in	ADP
iajs-3524	156	42	all	all	DET
iajs-3524	156	43	studied	study	VERB
iajs-3524	156	44	groups	group	NOUN
iajs-3524	156	45	as	as	SCONJ
iajs-3524	156	46	shown	show	VERB
iajs-3524	156	47	in	in	ADP
iajs-3524	156	48	figure	figure	NOUN
iajs-3524	156	49	3	3	NUM
iajs-3524	156	50	.	.	PUNCT
iajs-3524	157	1	the	the	DET
iajs-3524	157	2	results	result	NOUN
iajs-3524	157	3	also	also	ADV
iajs-3524	157	4	showed	show	VERB
iajs-3524	157	5	an	an	DET
iajs-3524	157	6	inversely	inversely	ADV
iajs-3524	157	7	correlated	correlate	VERB
iajs-3524	157	8	relationship	relationship	NOUN
iajs-3524	157	9	between	between	ADP
iajs-3524	157	10	collagenase-3	collagenase-3	NUM
iajs-3524	157	11	levels	level	NOUN
iajs-3524	157	12	and	and	CCONJ
iajs-3524	157	13	anti	anti	NOUN
iajs-3524	157	14	-	-	ADJ
iajs-3524	157	15	ccp	ccp	ADJ
iajs-3524	157	16	in	in	ADP
iajs-3524	157	17	g2	g2	PROPN
iajs-3524	157	18	and	and	CCONJ
iajs-3524	157	19	g3	g3	PROPN
iajs-3524	157	20	(	(	PUNCT
iajs-3524	157	21	r2=	r2=	PROPN
iajs-3524	157	22	0.35	0.35	NUM
iajs-3524	157	23	,	,	PUNCT
iajs-3524	157	24	r3=	r3=	NOUN
iajs-3524	157	25	0.17	0.17	NUM
iajs-3524	157	26	)	)	PUNCT
iajs-3524	157	27	.	.	PUNCT
iajs-3524	158	1	in	in	ADP
iajs-3524	158	2	contrast	contrast	NOUN
iajs-3524	158	3	,	,	PUNCT
iajs-3524	158	4	g1	g1	PROPN
iajs-3524	158	5	showed	show	VERB
iajs-3524	158	6	a	a	DET
iajs-3524	158	7	negative	negative	ADJ
iajs-3524	158	8	relationship	relationship	NOUN
iajs-3524	158	9	(	(	PUNCT
iajs-3524	158	10	r1=	r1=	NOUN
iajs-3524	158	11	-0.07	-0.07	NUM
iajs-3524	158	12	)	)	PUNCT
iajs-3524	158	13	,	,	PUNCT
iajs-3524	158	14	as	as	SCONJ
iajs-3524	158	15	seen	see	VERB
iajs-3524	158	16	in	in	ADP
iajs-3524	158	17	figure	figure	NOUN
iajs-3524	158	18	4	4	NUM
iajs-3524	158	19	.	.	PUNCT
iajs-3524	159	1	the	the	DET
iajs-3524	159	2	suppression	suppression	NOUN
iajs-3524	159	3	of	of	ADP
iajs-3524	159	4	cartilage	cartilage	NOUN
iajs-3524	159	5	development	development	NOUN
iajs-3524	159	6	and	and	CCONJ
iajs-3524	159	7	increased	increase	VERB
iajs-3524	159	8	chondrocyte	chondrocyte	NOUN
iajs-3524	159	9	death	death	NOUN
iajs-3524	159	10	may	may	AUX
iajs-3524	159	11	be	be	AUX
iajs-3524	159	12	the	the	DET
iajs-3524	159	13	underlying	underlying	ADJ
iajs-3524	159	14	mechanism	mechanism	NOUN
iajs-3524	159	15	for	for	ADP
iajs-3524	159	16	cl-3	cl-3	NOUN
iajs-3524	159	17	's	's	PART
iajs-3524	159	18	impacts	impact	NOUN
iajs-3524	159	19	on	on	ADP
iajs-3524	159	20	diabetic	diabetic	ADJ
iajs-3524	159	21	ra	ra	PROPN
iajs-3524	159	22	articular	articular	ADJ
iajs-3524	159	23	cartilage	cartilage	NOUN
iajs-3524	159	24	.	.	PUNCT
iajs-3524	160	1	however	however	ADV
iajs-3524	160	2	,	,	PUNCT
iajs-3524	160	3	further	further	ADJ
iajs-3524	160	4	research	research	NOUN
iajs-3524	160	5	is	be	AUX
iajs-3524	160	6	needed	need	VERB
iajs-3524	160	7	to	to	PART
iajs-3524	160	8	fully	fully	ADV
iajs-3524	160	9	understand	understand	VERB
iajs-3524	160	10	the	the	DET
iajs-3524	160	11	processes	process	NOUN
iajs-3524	160	12	.	.	PUNCT
iajs-3524	161	1	ihjpas	ihjpas	PROPN
iajs-3524	161	2	.	.	PUNCT
iajs-3524	162	1	2024	2024	NUM
iajs-3524	162	2	,	,	PUNCT
iajs-3524	162	3	37(4	37(4	NOUN
iajs-3524	162	4	)	)	PUNCT
iajs-3524	162	5	292	292	NUM
iajs-3524	162	6	figure	figure	NOUN
iajs-3524	162	7	2	2	NUM
iajs-3524	162	8	.	.	X
iajs-3524	162	9	relationship	relationship	NOUN
iajs-3524	162	10	between	between	ADP
iajs-3524	162	11	collagenase-3	collagenase-3	PROPN
iajs-3524	162	12	and	and	CCONJ
iajs-3524	162	13	esr	esr	PROPN
iajs-3524	162	14	.	.	PROPN
iajs-3524	162	15	figure	figure	NOUN
iajs-3524	162	16	3	3	NUM
iajs-3524	162	17	.	.	PUNCT
iajs-3524	162	18	relationship	relationship	NOUN
iajs-3524	162	19	between	between	ADP
iajs-3524	162	20	collagenase-3	collagenase-3	PROPN
iajs-3524	162	21	&	&	CCONJ
iajs-3524	162	22	hba1c	hba1c	PROPN
iajs-3524	162	23	.	.	PUNCT
iajs-3524	163	1	figure	figure	VERB
iajs-3524	163	2	4	4	NUM
iajs-3524	163	3	.	.	PUNCT
iajs-3524	163	4	relationship	relationship	NOUN
iajs-3524	163	5	between	between	ADP
iajs-3524	163	6	collagenase-3	collagenase-3	NUM
iajs-3524	163	7	and	and	CCONJ
iajs-3524	163	8	anti	anti	ADJ
iajs-3524	163	9	-	-	ADJ
iajs-3524	163	10	ccp	ccp	X
iajs-3524	163	11	.	.	PUNCT
iajs-3524	164	1	4	4	X
iajs-3524	164	2	.	.	X
iajs-3524	164	3	conclusion	conclusion	NOUN
iajs-3524	164	4	this	this	DET
iajs-3524	164	5	study	study	NOUN
iajs-3524	164	6	provides	provide	VERB
iajs-3524	164	7	solid	solid	ADJ
iajs-3524	164	8	evidence	evidence	NOUN
iajs-3524	164	9	that	that	PRON
iajs-3524	164	10	cl-3	cl-3	PRON
iajs-3524	164	11	contributes	contribute	VERB
iajs-3524	164	12	to	to	ADP
iajs-3524	164	13	an	an	DET
iajs-3524	164	14	increase	increase	NOUN
iajs-3524	164	15	in	in	ADP
iajs-3524	164	16	inflammation	inflammation	NOUN
iajs-3524	164	17	and	and	CCONJ
iajs-3524	164	18	joint	joint	ADJ
iajs-3524	164	19	degradation	degradation	NOUN
iajs-3524	164	20	in	in	ADP
iajs-3524	164	21	ra	ra	PROPN
iajs-3524	164	22	models	model	NOUN
iajs-3524	164	23	by	by	ADP
iajs-3524	164	24	demonstrating	demonstrate	VERB
iajs-3524	164	25	a	a	DET
iajs-3524	164	26	significant	significant	ADJ
iajs-3524	164	27	shift	shift	NOUN
iajs-3524	164	28	(	(	PUNCT
iajs-3524	164	29	either	either	CCONJ
iajs-3524	164	30	an	an	DET
iajs-3524	164	31	increase	increase	NOUN
iajs-3524	164	32	or	or	CCONJ
iajs-3524	164	33	a	a	DET
iajs-3524	164	34	decrease	decrease	NOUN
iajs-3524	164	35	)	)	PUNCT
iajs-3524	164	36	in	in	ADP
iajs-3524	164	37	cl-3	cl-3	NOUN
iajs-3524	164	38	and	and	CCONJ
iajs-3524	164	39	anti	anti	ADJ
iajs-3524	164	40	-	-	ADJ
iajs-3524	164	41	ccp	ccp	ADJ
iajs-3524	164	42	levels	level	NOUN
iajs-3524	164	43	.	.	PUNCT
iajs-3524	165	1	according	accord	VERB
iajs-3524	165	2	to	to	ADP
iajs-3524	165	3	evidence	evidence	NOUN
iajs-3524	165	4	that	that	PRON
iajs-3524	165	5	demonstrates	demonstrate	VERB
iajs-3524	165	6	it	it	PRON
iajs-3524	165	7	is	be	AUX
iajs-3524	165	8	essential	essential	ADJ
iajs-3524	165	9	ihjpas	ihjpa	NOUN
iajs-3524	165	10	.	.	PUNCT
iajs-3524	166	1	2024	2024	NUM
iajs-3524	166	2	,	,	PUNCT
iajs-3524	166	3	37(4	37(4	PROPN
iajs-3524	166	4	)	)	PUNCT
iajs-3524	166	5	293	293	NUM
iajs-3524	166	6	for	for	ADP
iajs-3524	166	7	a	a	DET
iajs-3524	166	8	protracted	protract	VERB
iajs-3524	166	9	inflammatory	inflammatory	ADJ
iajs-3524	166	10	response	response	NOUN
iajs-3524	166	11	that	that	PRON
iajs-3524	166	12	takes	take	VERB
iajs-3524	166	13	place	place	NOUN
iajs-3524	166	14	in	in	ADP
iajs-3524	166	15	the	the	DET
iajs-3524	166	16	effector	effector	NOUN
iajs-3524	166	17	phase	phase	NOUN
iajs-3524	166	18	of	of	ADP
iajs-3524	166	19	arthritis	arthritis	NOUN
iajs-3524	166	20	,	,	PUNCT
iajs-3524	166	21	cl-3	cl-3	PRON
iajs-3524	166	22	may	may	AUX
iajs-3524	166	23	have	have	VERB
iajs-3524	166	24	a	a	DET
iajs-3524	166	25	job	job	NOUN
iajs-3524	166	26	in	in	ADP
iajs-3524	166	27	managing	manage	VERB
iajs-3524	166	28	the	the	DET
iajs-3524	166	29	inflammatory	inflammatory	ADJ
iajs-3524	166	30	response	response	NOUN
iajs-3524	166	31	in	in	ADP
iajs-3524	166	32	addition	addition	NOUN
iajs-3524	166	33	to	to	ADP
iajs-3524	166	34	damaging	damaging	ADJ
iajs-3524	166	35	cartilage	cartilage	NOUN
iajs-3524	166	36	.	.	PUNCT
iajs-3524	167	1	this	this	DET
iajs-3524	167	2	information	information	NOUN
iajs-3524	167	3	suggests	suggest	VERB
iajs-3524	167	4	that	that	SCONJ
iajs-3524	167	5	cl-3	cl-3	PRON
iajs-3524	167	6	may	may	AUX
iajs-3524	167	7	have	have	VERB
iajs-3524	167	8	a	a	DET
iajs-3524	167	9	role	role	NOUN
iajs-3524	167	10	in	in	ADP
iajs-3524	167	11	controlling	control	VERB
iajs-3524	167	12	the	the	DET
iajs-3524	167	13	inflammatory	inflammatory	ADJ
iajs-3524	167	14	response	response	NOUN
iajs-3524	167	15	.	.	PUNCT
iajs-3524	168	1	these	these	DET
iajs-3524	168	2	results	result	NOUN
iajs-3524	168	3	showed	show	VERB
iajs-3524	168	4	that	that	SCONJ
iajs-3524	168	5	these	these	DET
iajs-3524	168	6	features	feature	NOUN
iajs-3524	168	7	have	have	VERB
iajs-3524	168	8	the	the	DET
iajs-3524	168	9	potential	potential	NOUN
iajs-3524	168	10	to	to	PART
iajs-3524	168	11	be	be	AUX
iajs-3524	168	12	use	use	NOUN
iajs-3524	168	13	as	as	ADP
iajs-3524	168	14	a	a	DET
iajs-3524	168	15	biochemical	biochemical	ADJ
iajs-3524	168	16	diagnostic	diagnostic	NOUN
iajs-3524	168	17	for	for	ADP
iajs-3524	168	18	the	the	DET
iajs-3524	168	19	early	early	ADJ
iajs-3524	168	20	diagnosis	diagnosis	NOUN
iajs-3524	168	21	of	of	ADP
iajs-3524	168	22	diabetes	diabetes	NOUN
iajs-3524	168	23	in	in	ADP
iajs-3524	168	24	ra	ra	PROPN
iajs-3524	168	25	patients	patient	NOUN
iajs-3524	168	26	.	.	PUNCT
iajs-3524	169	1	in	in	ADP
iajs-3524	169	2	addition	addition	NOUN
iajs-3524	169	3	to	to	ADP
iajs-3524	169	4	this	this	PRON
iajs-3524	169	5	,	,	PUNCT
iajs-3524	169	6	a	a	DET
iajs-3524	169	7	strong	strong	ADJ
iajs-3524	169	8	positive	positive	ADJ
iajs-3524	169	9	or	or	CCONJ
iajs-3524	169	10	negative	negative	ADJ
iajs-3524	169	11	association	association	NOUN
iajs-3524	169	12	between	between	ADP
iajs-3524	169	13	cl-3	cl-3	NOUN
iajs-3524	169	14	and	and	CCONJ
iajs-3524	169	15	all	all	DET
iajs-3524	169	16	parameters	parameter	NOUN
iajs-3524	169	17	for	for	ADP
iajs-3524	169	18	all	all	DET
iajs-3524	169	19	groups	group	NOUN
iajs-3524	169	20	revealed	reveal	VERB
iajs-3524	169	21	a	a	DET
iajs-3524	169	22	good	good	ADJ
iajs-3524	169	23	connected	connected	ADJ
iajs-3524	169	24	biomarker	biomarker	NOUN
iajs-3524	169	25	with	with	ADP
iajs-3524	169	26	these	these	DET
iajs-3524	169	27	patients	patient	NOUN
iajs-3524	169	28	,	,	PUNCT
iajs-3524	169	29	suggesting	suggest	VERB
iajs-3524	169	30	that	that	SCONJ
iajs-3524	169	31	it	it	PRON
iajs-3524	169	32	would	would	AUX
iajs-3524	169	33	be	be	AUX
iajs-3524	169	34	possible	possible	ADJ
iajs-3524	169	35	to	to	PART
iajs-3524	169	36	employ	employ	VERB
iajs-3524	169	37	the	the	DET
iajs-3524	169	38	most	most	ADV
iajs-3524	169	39	effective	effective	ADJ
iajs-3524	169	40	medicine	medicine	NOUN
iajs-3524	169	41	and	and	CCONJ
iajs-3524	169	42	treatment	treatment	NOUN
iajs-3524	169	43	.	.	PUNCT
iajs-3524	170	1	acknowledgment	acknowledgment	NOUN
iajs-3524	170	2	the	the	DET
iajs-3524	170	3	authors	author	NOUN
iajs-3524	170	4	thank	thank	VERB
iajs-3524	170	5	the	the	DET
iajs-3524	170	6	department	department	NOUN
iajs-3524	170	7	of	of	ADP
iajs-3524	170	8	chemistry	chemistry	NOUN
iajs-3524	170	9	,	,	PUNCT
iajs-3524	170	10	college	college	NOUN
iajs-3524	170	11	of	of	ADP
iajs-3524	170	12	education	education	NOUN
iajs-3524	170	13	for	for	ADP
iajs-3524	170	14	pure	pure	ADJ
iajs-3524	170	15	science	science	NOUN
iajs-3524	170	16	(	(	PUNCT
iajs-3524	170	17	ibn	ibn	PROPN
iajs-3524	170	18	al	al	PROPN
iajs-3524	170	19	–	–	PUNCT
iajs-3524	170	20	haitham	haitham	PROPN
iajs-3524	170	21	)	)	PUNCT
iajs-3524	170	22	,	,	PUNCT
iajs-3524	170	23	university	university	NOUN
iajs-3524	170	24	of	of	ADP
iajs-3524	170	25	baghdad	baghdad	PROPN
iajs-3524	170	26	for	for	ADP
iajs-3524	170	27	research	research	NOUN
iajs-3524	170	28	approval	approval	NOUN
iajs-3524	170	29	.	.	PUNCT
iajs-3524	171	1	conflict	conflict	NOUN
iajs-3524	171	2	of	of	ADP
iajs-3524	171	3	interest	interest	NOUN
iajs-3524	171	4	the	the	DET
iajs-3524	171	5	authors	author	NOUN
iajs-3524	171	6	declare	declare	VERB
iajs-3524	171	7	that	that	SCONJ
iajs-3524	171	8	they	they	PRON
iajs-3524	171	9	have	have	VERB
iajs-3524	171	10	no	no	DET
iajs-3524	171	11	conflicts	conflict	NOUN
iajs-3524	171	12	of	of	ADP
iajs-3524	171	13	interest	interest	NOUN
iajs-3524	171	14	.	.	PUNCT
iajs-3524	172	1	funding	fund	VERB
iajs-3524	172	2	no	no	DET
iajs-3524	172	3	founding	founding	NOUN
iajs-3524	172	4	.	.	PUNCT
iajs-3524	173	1	ethical	ethical	ADJ
iajs-3524	173	2	clearance	clearance	NOUN
iajs-3524	173	3	this	this	DET
iajs-3524	173	4	work	work	NOUN
iajs-3524	173	5	has	have	AUX
iajs-3524	173	6	been	be	AUX
iajs-3524	173	7	approved	approve	VERB
iajs-3524	173	8	by	by	ADP
iajs-3524	173	9	the	the	DET
iajs-3524	173	10	scientific	scientific	ADJ
iajs-3524	173	11	committee	committee	NOUN
iajs-3524	173	12	at	at	ADP
iajs-3524	173	13	the	the	DET
iajs-3524	173	14	university	university	NOUN
iajs-3524	173	15	of	of	ADP
iajs-3524	173	16	baghdad/	baghdad/	NUM
iajs-3524	173	17	college	college	NOUN
iajs-3524	173	18	of	of	ADP
iajs-3524	173	19	education	education	NOUN
iajs-3524	173	20	for	for	ADP
iajs-3524	173	21	pure	pure	ADJ
iajs-3524	173	22	science	science	NOUN
iajs-3524	173	23	(	(	PUNCT
iajs-3524	173	24	ibn	ibn	PROPN
iajs-3524	173	25	al	al	PROPN
iajs-3524	173	26	–	–	PUNCT
iajs-3524	173	27	haitham	haitham	PROPN
iajs-3524	173	28	)	)	PUNCT
iajs-3524	173	29	,	,	PUNCT
iajs-3524	173	30	which	which	PRON
iajs-3524	173	31	is	be	AUX
iajs-3524	173	32	consistent	consistent	ADJ
iajs-3524	173	33	with	with	ADP
iajs-3524	173	34	the	the	DET
iajs-3524	173	35	instructions	instruction	NOUN
iajs-3524	173	36	of	of	ADP
iajs-3524	173	37	the	the	DET
iajs-3524	173	38	iraqi	iraqi	ADJ
iajs-3524	173	39	ministry	ministry	PROPN
iajs-3524	173	40	of	of	ADP
iajs-3524	173	41	health	health	PROPN
iajs-3524	173	42	and	and	CCONJ
iajs-3524	173	43	environment	environment	NOUN
iajs-3524	173	44	(	(	PUNCT
iajs-3524	173	45	no	no	INTJ
iajs-3524	173	46	.	.	NOUN
iajs-3524	173	47	15765	15765	NUM
iajs-3524	173	48	on	on	ADP
iajs-3524	173	49	4/10/2022	4/10/2022	NUM
iajs-3524	173	50	)	)	PUNCT
iajs-3524	173	51	.	.	PUNCT
iajs-3524	174	1	references	reference	NOUN
iajs-3524	174	2	1	1	NUM
iajs-3524	174	3	.	.	PUNCT
iajs-3524	175	1	smolen	smolen	PROPN
iajs-3524	175	2	,	,	PUNCT
iajs-3524	175	3	j.s	j.s	PROPN
iajs-3524	175	4	.	.	PUNCT
iajs-3524	175	5	;	;	PUNCT
iajs-3524	175	6	aletaha	aletaha	PROPN
iajs-3524	175	7	d.	d.	PROPN
iajs-3524	175	8	;	;	PUNCT
iajs-3524	175	9	barton	barton	PROPN
iajs-3524	175	10	a.	a.	PROPN
iajs-3524	175	11	;	;	PUNCT
iajs-3524	175	12	burmester	burmester	PROPN
iajs-3524	175	13	g.r	g.r	PROPN
iajs-3524	175	14	.	.	PROPN
iajs-3524	175	15	;	;	PUNCT
iajs-3524	175	16	emery	emery	PROPN
iajs-3524	175	17	,	,	PUNCT
iajs-3524	175	18	p.	p.	PROPN
iajs-3524	175	19	;	;	PUNCT
iajs-3524	175	20	firestein	firestein	PROPN
iajs-3524	175	21	g.s	g.s	PROPN
iajs-3524	175	22	.	.	PUNCT
iajs-3524	176	1	rheumatoid	rheumatoid	PROPN
iajs-3524	176	2	arthritis	arthritis	NOUN
iajs-3524	176	3	.	.	PUNCT
iajs-3524	177	1	nature	nature	NOUN
iajs-3524	177	2	review	review	NOUN
iajs-3524	177	3	disease	disease	NOUN
iajs-3524	177	4	primers	primer	NOUN
iajs-3524	177	5	2018	2018	NUM
iajs-3524	177	6	,	,	PUNCT
iajs-3524	177	7	4(1	4(1	NOUN
iajs-3524	177	8	)	)	PUNCT
iajs-3524	177	9	,	,	PUNCT
iajs-3524	177	10	18001	18001	NUM
iajs-3524	177	11	.	.	PUNCT
iajs-3524	178	1	https://doi.org/10.1038/nrdp.2018.1	https://doi.org/10.1038/nrdp.2018.1	NUM
iajs-3524	178	2	.	.	PUNCT
iajs-3524	179	1	2	2	X
iajs-3524	179	2	.	.	X
iajs-3524	179	3	omran	omran	PROPN
iajs-3524	179	4	,	,	PUNCT
iajs-3524	179	5	r.h	r.h	PROPN
iajs-3524	179	6	.	.	PROPN
iajs-3524	179	7	;	;	PUNCT
iajs-3524	179	8	zahra'a	zahra'a	X
iajs-3524	179	9	,	,	PUNCT
iajs-3524	179	10	a.a	a.a	PROPN
iajs-3524	179	11	.	.	PROPN
iajs-3524	179	12	;	;	PUNCT
iajs-3524	179	13	alrawi	alrawi	PROPN
iajs-3524	179	14	,	,	PUNCT
iajs-3524	179	15	a.a	a.a	PROPN
iajs-3524	179	16	.	.	PROPN
iajs-3524	179	17	evaluation	evaluation	NOUN
iajs-3524	179	18	of	of	ADP
iajs-3524	179	19	some	some	DET
iajs-3524	179	20	new	new	ADJ
iajs-3524	179	21	cytokines	cytokine	NOUN
iajs-3524	179	22	in	in	ADP
iajs-3524	179	23	rheumatoid	rheumatoid	NOUN
iajs-3524	179	24	arthritis	arthritis	NOUN
iajs-3524	179	25	.	.	PUNCT
iajs-3524	180	1	journal	journal	NOUN
iajs-3524	180	2	of	of	ADP
iajs-3524	180	3	the	the	DET
iajs-3524	180	4	faculty	faculty	NOUN
iajs-3524	180	5	of	of	ADP
iajs-3524	180	6	medicine	medicine	NOUN
iajs-3524	180	7	baghdad	baghdad	PROPN
iajs-3524	180	8	2022	2022	NUM
iajs-3524	180	9	,	,	PUNCT
iajs-3524	180	10	64(3	64(3	NUM
iajs-3524	180	11	)	)	PUNCT
iajs-3524	180	12	,	,	PUNCT
iajs-3524	180	13	159	159	NUM
iajs-3524	180	14	-	-	SYM
iajs-3524	180	15	162	162	NUM
iajs-3524	180	16	.	.	PUNCT
iajs-3524	181	1	https://doi.org/10.32007/jfacmedbagdad.6431963	https://doi.org/10.32007/jfacmedbagdad.6431963	NUM
iajs-3524	181	2	.	.	PUNCT
iajs-3524	182	1	3	3	NUM
iajs-3524	182	2	.	.	X
iajs-3524	182	3	lestarini	lestarini	PROPN
iajs-3524	182	4	,	,	PUNCT
iajs-3524	182	5	a.	a.	NOUN
iajs-3524	182	6	;	;	PUNCT
iajs-3524	182	7	aryastuti	aryastuti	PROPN
iajs-3524	182	8	,	,	PUNCT
iajs-3524	182	9	a.a	a.a	PROPN
iajs-3524	182	10	.	.	PROPN
iajs-3524	182	11	;	;	PUNCT
iajs-3524	182	12	witari	witari	PROPN
iajs-3524	182	13	,	,	PUNCT
iajs-3524	182	14	n.p	n.p	PROPN
iajs-3524	182	15	.	.	PROPN
iajs-3524	182	16	;	;	PUNCT
iajs-3524	182	17	sutarka	sutarka	PROPN
iajs-3524	182	18	,	,	PUNCT
iajs-3524	182	19	i.w	i.w	PROPN
iajs-3524	182	20	.	.	PROPN
iajs-3524	182	21	;	;	PUNCT
iajs-3524	182	22	wardani	wardani	PROPN
iajs-3524	182	23	,	,	PUNCT
iajs-3524	182	24	n.w	n.w	PROPN
iajs-3524	182	25	.	.	PROPN
iajs-3524	182	26	;	;	PUNCT
iajs-3524	183	1	hastuti	hastuti	PROPN
iajs-3524	183	2	,	,	PUNCT
iajs-3524	183	3	p.	p.	NOUN
iajs-3524	183	4	;	;	PUNCT
iajs-3524	183	5	sadewa	sadewa	PROPN
iajs-3524	183	6	,	,	PUNCT
iajs-3524	183	7	a.h	a.h	PROPN
iajs-3524	183	8	.	.	PROPN
iajs-3524	183	9	mcp-1	mcp-1	NOUN
iajs-3524	183	10	serum	serum	NOUN
iajs-3524	183	11	levels	level	NOUN
iajs-3524	183	12	were	be	AUX
iajs-3524	183	13	higher	high	ADJ
iajs-3524	183	14	in	in	ADP
iajs-3524	183	15	patient	patient	NOUN
iajs-3524	183	16	with	with	ADP
iajs-3524	183	17	diabetic	diabetic	ADJ
iajs-3524	183	18	nephropathy	nephropathy	NOUN
iajs-3524	183	19	among	among	ADP
iajs-3524	183	20	balinese	balinese	PROPN
iajs-3524	183	21	.	.	PUNCT
iajs-3524	184	1	indian	indian	PROPN
iajs-3524	184	2	journal	journal	PROPN
iajs-3524	184	3	of	of	ADP
iajs-3524	184	4	public	public	ADJ
iajs-3524	184	5	health	health	NOUN
iajs-3524	184	6	2020	2020	NUM
iajs-3524	184	7	,	,	PUNCT
iajs-3524	184	8	11(1	11(1	NUM
iajs-3524	184	9	)	)	PUNCT
iajs-3524	184	10	,	,	PUNCT
iajs-3524	184	11	1351	1351	NUM
iajs-3524	184	12	.	.	PUNCT
iajs-3524	185	1	https://www.researchgate.net/profile/asri-lestarini/publication/342688022	https://www.researchgate.net/profile/asri-lestarini/publication/342688022	NOUN
iajs-3524	185	2	.	.	PROPN
iajs-3524	185	3	4	4	NUM
iajs-3524	185	4	.	.	X
iajs-3524	185	5	mengshol	mengshol	NOUN
iajs-3524	185	6	,	,	PUNCT
iajs-3524	185	7	j.a	j.a	PROPN
iajs-3524	185	8	.	.	PROPN
iajs-3524	185	9	;	;	PUNCT
iajs-3524	185	10	mix	mix	X
iajs-3524	185	11	,	,	PUNCT
iajs-3524	185	12	k.s	k.s	PROPN
iajs-3524	185	13	.	.	PROPN
iajs-3524	185	14	;	;	PUNCT
iajs-3524	185	15	brinckerhoff	brinckerhoff	PROPN
iajs-3524	185	16	c.e	c.e	PROPN
iajs-3524	185	17	.	.	PROPN
iajs-3524	185	18	matrix	matrix	NOUN
iajs-3524	185	19	metalloproteinases	metalloproteinase	NOUN
iajs-3524	185	20	as	as	ADP
iajs-3524	185	21	therapeutic	therapeutic	ADJ
iajs-3524	185	22	targets	target	NOUN
iajs-3524	185	23	in	in	ADP
iajs-3524	185	24	arthritic	arthritic	ADJ
iajs-3524	185	25	diseases	disease	NOUN
iajs-3524	185	26	:	:	PUNCT
iajs-3524	185	27	bull’s	bull’s	ADJ
iajs-3524	185	28	-	-	PUNCT
iajs-3524	185	29	eye	eye	NOUN
iajs-3524	185	30	or	or	CCONJ
iajs-3524	185	31	missing	miss	VERB
iajs-3524	185	32	the	the	DET
iajs-3524	185	33	mark	mark	NOUN
iajs-3524	185	34	.	.	PUNCT
iajs-3524	186	1	arthritis	arthritis	NOUN
iajs-3524	186	2	and	and	CCONJ
iajs-3524	186	3	rheumatism	rheumatism	NOUN
iajs-3524	186	4	2002	2002	NUM
iajs-3524	186	5	,	,	PUNCT
iajs-3524	186	6	46(1	46(1	PROPN
iajs-3524	186	7	)	)	PUNCT
iajs-3524	186	8	,	,	PUNCT
iajs-3524	186	9	13–20	13–20	NUM
iajs-3524	186	10	.	.	PUNCT
iajs-3524	187	1	https://doi.org/10.1002/art.497	https://doi.org/10.1002/art.497	PROPN
iajs-3524	187	2	.	.	PROPN
iajs-3524	188	1	5	5	NUM
iajs-3524	188	2	.	.	X
iajs-3524	188	3	cui	cui	PROPN
iajs-3524	188	4	,	,	PUNCT
iajs-3524	188	5	n.	n.	PROPN
iajs-3524	188	6	;	;	PUNCT
iajs-3524	188	7	hu	hu	PROPN
iajs-3524	188	8	,	,	PUNCT
iajs-3524	188	9	m.	m.	NOUN
iajs-3524	188	10	;	;	PUNCT
iajs-3524	188	11	khalil	khalil	PROPN
iajs-3524	188	12	,	,	PUNCT
iajs-3524	188	13	r.a	r.a	PROPN
iajs-3524	188	14	.	.	PROPN
iajs-3524	188	15	chapter	chapter	NOUN
iajs-3524	188	16	one	one	NUM
iajs-3524	188	17	-	-	PUNCT
iajs-3524	188	18	biochemical	biochemical	ADJ
iajs-3524	188	19	and	and	CCONJ
iajs-3524	188	20	biological	biological	ADJ
iajs-3524	188	21	attributes	attribute	NOUN
iajs-3524	188	22	of	of	ADP
iajs-3524	188	23	matrix	matrix	NOUN
iajs-3524	188	24	metalloproteinases	metalloproteinase	NOUN
iajs-3524	188	25	.	.	PUNCT
iajs-3524	189	1	progress	progress	NOUN
iajs-3524	189	2	in	in	ADP
iajs-3524	189	3	molecular	molecular	ADJ
iajs-3524	189	4	biology	biology	NOUN
iajs-3524	189	5	and	and	CCONJ
iajs-3524	189	6	translational	translational	ADJ
iajs-3524	189	7	science	science	NOUN
iajs-3524	189	8	2017	2017	NUM
iajs-3524	189	9	,	,	PUNCT
iajs-3524	189	10	147(1	147(1	NUM
iajs-3524	189	11	)	)	PUNCT
iajs-3524	189	12	,	,	PUNCT
iajs-3524	189	13	1–73	1–73	PROPN
iajs-3524	189	14	.	.	PUNCT
iajs-3524	190	1	https://doi.org/10.1016/bs.pmbts.2017.02.005	https://doi.org/10.1016/bs.pmbts.2017.02.005	X
iajs-3524	190	2	.	.	PUNCT
iajs-3524	191	1	6	6	X
iajs-3524	191	2	.	.	X
iajs-3524	191	3	schieir	schieir	ADJ
iajs-3524	191	4	,	,	PUNCT
iajs-3524	191	5	o.	o.	PROPN
iajs-3524	191	6	;	;	PUNCT
iajs-3524	191	7	tosevski	tosevski	PROPN
iajs-3524	191	8	,	,	PUNCT
iajs-3524	191	9	c.	c.	PROPN
iajs-3524	191	10	;	;	PUNCT
iajs-3524	191	11	glazier	glazier	NOUN
iajs-3524	191	12	,	,	PUNCT
iajs-3524	191	13	r.h	r.h	PROPN
iajs-3524	191	14	.	.	PROPN
iajs-3524	191	15	;	;	PUNCT
iajs-3524	191	16	hogg	hogg	PROPN
iajs-3524	191	17	-	-	PUNCT
iajs-3524	191	18	johnson	johnson	PROPN
iajs-3524	191	19	,	,	PUNCT
iajs-3524	191	20	s.	s.	PROPN
iajs-3524	191	21	;	;	PUNCT
iajs-3524	191	22	badley	badley	PROPN
iajs-3524	191	23	,	,	PUNCT
iajs-3524	191	24	e.m	e.m	PROPN
iajs-3524	191	25	.	.	PROPN
iajs-3524	191	26	incident	incident	NOUN
iajs-3524	191	27	myocardial	myocardial	ADJ
iajs-3524	191	28	infarction	infarction	NOUN
iajs-3524	191	29	associated	associate	VERB
iajs-3524	191	30	aith	aith	ADP
iajs-3524	191	31	major	major	ADJ
iajs-3524	191	32	types	type	NOUN
iajs-3524	191	33	of	of	ADP
iajs-3524	191	34	arthritis	arthritis	NOUN
iajs-3524	191	35	in	in	ADP
iajs-3524	191	36	the	the	DET
iajs-3524	191	37	general	general	ADJ
iajs-3524	191	38	population	population	NOUN
iajs-3524	191	39	:	:	PUNCT
iajs-3524	191	40	a	a	DET
iajs-3524	191	41	systematic	systematic	ADJ
iajs-3524	191	42	review	review	NOUN
iajs-3524	191	43	and	and	CCONJ
iajs-3524	191	44	meta	meta	ADJ
iajs-3524	191	45	-	-	PUNCT
iajs-3524	191	46	analysis	analysis	NOUN
iajs-3524	191	47	.	.	PUNCT
iajs-3524	192	1	annals	annal	NOUN
iajs-3524	192	2	of	of	ADP
iajs-3524	192	3	the	the	DET
iajs-3524	192	4	rheumatic	rheumatic	ADJ
iajs-3524	192	5	diseases	disease	NOUN
iajs-3524	192	6	2017	2017	NUM
iajs-3524	192	7	,	,	PUNCT
iajs-3524	192	8	76(8	76(8	NUM
iajs-3524	192	9	)	)	PUNCT
iajs-3524	192	10	,	,	PUNCT
iajs-3524	192	11	1404–1396	1404–1396	NUM
iajs-3524	192	12	.	.	PUNCT
iajs-3524	193	1	https://doi.org/10.1136/annrheumdis-2016-210275	https://doi.org/10.1136/annrheumdis-2016-210275	PROPN
iajs-3524	193	2	.	.	PROPN
iajs-3524	193	3	7	7	X
iajs-3524	193	4	.	.	X
iajs-3524	193	5	al	al	PROPN
iajs-3524	193	6	-	-	PUNCT
iajs-3524	193	7	ameri	ameri	PROPN
iajs-3524	193	8	,	,	PUNCT
iajs-3524	193	9	m.a	m.a	PROPN
iajs-3524	193	10	.	.	PROPN
iajs-3524	193	11	;	;	PUNCT
iajs-3524	193	12	al	al	PROPN
iajs-3524	193	13	-	-	PUNCT
iajs-3524	193	14	rubaei	rubaei	NOUN
iajs-3524	193	15	,	,	PUNCT
iajs-3524	193	16	z.	z.	PROPN
iajs-3524	193	17	study	study	PROPN
iajs-3524	193	18	of	of	ADP
iajs-3524	193	19	tumor	tumor	NOUN
iajs-3524	193	20	necrosis	necrosis	NOUN
iajs-3524	193	21	factor	factor	NOUN
iajs-3524	193	22	-	-	PUNCT
iajs-3524	193	23	β	β	X
iajs-3524	193	24	(	(	PUNCT
iajs-3524	193	25	lymphotoxin	lymphotoxin	PROPN
iajs-3524	193	26	)	)	PUNCT
iajs-3524	193	27	and	and	CCONJ
iajs-3524	193	28	cell	cell	NOUN
iajs-3524	193	29	death	death	NOUN
iajs-3524	193	30	receptor	receptor	NOUN
iajs-3524	193	31	(	(	PUNCT
iajs-3524	193	32	tnfr-2	tnfr-2	NUM
iajs-3524	193	33	)	)	PUNCT
iajs-3524	193	34	in	in	ADP
iajs-3524	193	35	rhumatiod	rhumatiod	NOUN
iajs-3524	193	36	arthritis	arthritis	NOUN
iajs-3524	193	37	with	with	ADP
iajs-3524	193	38	type	type	NOUN
iajs-3524	193	39	2	2	NUM
iajs-3524	193	40	diabetes	diabetes	NOUN
iajs-3524	193	41	mellitus	mellitus	NOUN
iajs-3524	193	42	.	.	PUNCT
iajs-3524	194	1	pakistan	pakistan	PROPN
iajs-3524	194	2	journal	journal	PROPN
iajs-3524	194	3	of	of	ADP
iajs-3524	194	4	medical	medical	ADJ
iajs-3524	194	5	and	and	CCONJ
iajs-3524	194	6	health	health	NOUN
iajs-3524	194	7	sciences	science	NOUN
iajs-3524	194	8	2022	2022	NUM
iajs-3524	194	9	,	,	PUNCT
iajs-3524	194	10	16(6	16(6	NUM
iajs-3524	194	11	)	)	PUNCT
iajs-3524	194	12	,	,	PUNCT
iajs-3524	194	13	468–468	468–468	NUM
iajs-3524	194	14	.	.	PUNCT
iajs-3524	195	1	https://doi.org/10.53350/pjmhs22166468	https://doi.org/10.53350/pjmhs22166468	NOUN
iajs-3524	195	2	.	.	PUNCT
iajs-3524	196	1	https://doi.org/10.1038/nrdp.2018.1	https://doi.org/10.1038/nrdp.2018.1	PROPN
iajs-3524	196	2	.	.	PUNCT
iajs-3524	197	1	https://doi.org/10.32007/jfacmedbagdad.6431963	https://doi.org/10.32007/jfacmedbagdad.6431963	PROPN
iajs-3524	197	2	https://www.researchgate.net/profile/asri-lestarini/publication/342688022	https://www.researchgate.net/profile/asri-lestarini/publication/342688022	PROPN
iajs-3524	198	1	https://doi.org/10.1002/art.497	https://doi.org/10.1002/art.497	PROPN
iajs-3524	198	2	https://doi.org/10.1016/bs.pmbts.2017.02.005	https://doi.org/10.1016/bs.pmbts.2017.02.005	NOUN
iajs-3524	198	3	https://doi.org/10.1136/annrheumdis-2016-210275	https://doi.org/10.1136/annrheumdis-2016-210275	PROPN
iajs-3524	198	4	https://doi.org/10.53350/pjmhs22166468	https://doi.org/10.53350/pjmhs22166468	NOUN
iajs-3524	198	5	ihjpas	ihjpa	VERB
iajs-3524	198	6	.	.	PUNCT
iajs-3524	199	1	2024	2024	NUM
iajs-3524	199	2	,	,	PUNCT
iajs-3524	199	3	37(4	37(4	NUM
iajs-3524	199	4	)	)	PUNCT
iajs-3524	199	5	294	294	NUM
iajs-3524	199	6	8	8	NUM
iajs-3524	199	7	.	.	PUNCT
iajs-3524	199	8	stahle	stahle	NOUN
iajs-3524	199	9	-	-	PUNCT
iajs-3524	199	10	backdahl	backdahl	NOUN
iajs-3524	199	11	,	,	PUNCT
iajs-3524	199	12	m.	m.	NOUN
iajs-3524	199	13	;	;	PUNCT
iajs-3524	199	14	sandstedt	sandstedt	PROPN
iajs-3524	199	15	,	,	PUNCT
iajs-3524	199	16	b.	b.	PROPN
iajs-3524	199	17	;	;	PUNCT
iajs-3524	199	18	bruce	bruce	PROPN
iajs-3524	199	19	,	,	PUNCT
iajs-3524	199	20	k.	k.	PROPN
iajs-3524	199	21	;	;	PUNCT
iajs-3524	199	22	lindahl	lindahl	PROPN
iajs-3524	199	23	,	,	PUNCT
iajs-3524	199	24	a.	a.	PROPN
iajs-3524	199	25	;	;	PUNCT
iajs-3524	199	26	jimenez	jimenez	PROPN
iajs-3524	199	27	,	,	PUNCT
iajs-3524	199	28	m.g	m.g	PROPN
iajs-3524	199	29	.	.	PROPN
iajs-3524	199	30	;	;	PUNCT
iajs-3524	199	31	vega	vega	PROPN
iajs-3524	199	32	,	,	PUNCT
iajs-3524	199	33	j.a	j.a	PROPN
iajs-3524	199	34	.	.	PROPN
iajs-3524	199	35	;	;	PUNCT
iajs-3524	199	36	lópez	lópez	NOUN
iajs-3524	199	37	-	-	PUNCT
iajs-3524	199	38	otín	otín	NOUN
iajs-3524	199	39	c.	c.	NOUN
iajs-3524	199	40	collagenase-3	collagenase-3	NUM
iajs-3524	199	41	(	(	PUNCT
iajs-3524	199	42	mmp-13	mmp-13	NOUN
iajs-3524	199	43	)	)	PUNCT
iajs-3524	199	44	is	be	AUX
iajs-3524	199	45	expressed	express	VERB
iajs-3524	199	46	during	during	ADP
iajs-3524	199	47	human	human	ADJ
iajs-3524	199	48	fetalossification	fetalossification	NOUN
iajs-3524	199	49	and	and	CCONJ
iajs-3524	199	50	re	re	VERB
iajs-3524	199	51	-	-	VERB
iajs-3524	199	52	expressed	express	VERB
iajs-3524	199	53	in	in	ADP
iajs-3524	199	54	postnatal	postnatal	ADJ
iajs-3524	199	55	bone	bone	NOUN
iajs-3524	199	56	remodeling	remodeling	NOUN
iajs-3524	199	57	and	and	CCONJ
iajs-3524	199	58	in	in	ADP
iajs-3524	199	59	rheumatoid	rheumatoid	NOUN
iajs-3524	199	60	arthritis	arthritis	NOUN
iajs-3524	199	61	.	.	PUNCT
iajs-3524	200	1	laboratory	laboratory	NOUN
iajs-3524	200	2	investigation	investigation	NOUN
iajs-3524	200	3	1997	1997	NUM
iajs-3524	200	4	,	,	PUNCT
iajs-3524	200	5	76(5	76(5	NUM
iajs-3524	200	6	)	)	PUNCT
iajs-3524	200	7	,	,	PUNCT
iajs-3524	200	8	717	717	NUM
iajs-3524	200	9	–	–	PUNCT
iajs-3524	200	10	728	728	NUM
iajs-3524	200	11	.	.	PUNCT
iajs-3524	201	1	https://europepmc.org/article/med/9166290	https://europepmc.org/article/med/9166290	NUM
iajs-3524	201	2	.	.	PUNCT
iajs-3524	202	1	9	9	X
iajs-3524	202	2	.	.	X
iajs-3524	202	3	boneva	boneva	PROPN
iajs-3524	202	4	,	,	PUNCT
iajs-3524	202	5	b.	b.	PROPN
iajs-3524	202	6	;	;	PUNCT
iajs-3524	202	7	ralchev	ralchev	ADJ
iajs-3524	202	8	,	,	PUNCT
iajs-3524	202	9	n.	n.	NOUN
iajs-3524	202	10	;	;	PUNCT
iajs-3524	202	11	ganova	ganova	PROPN
iajs-3524	202	12	,	,	PUNCT
iajs-3524	202	13	p.	p.	NOUN
iajs-3524	202	14	;	;	PUNCT
iajs-3524	203	1	tchorbanov	tchorbanov	PROPN
iajs-3524	203	2	,	,	PUNCT
iajs-3524	203	3	a.	a.	NOUN
iajs-3524	203	4	;	;	PUNCT
iajs-3524	203	5	mihaylova	mihaylova	X
iajs-3524	203	6	,	,	PUNCT
iajs-3524	203	7	n.	n.	PROPN
iajs-3524	203	8	collagenaseinduced	collagenaseinduce	VERB
iajs-3524	203	9	mouse	mouse	NOUN
iajs-3524	203	10	model	model	NOUN
iajs-3524	203	11	of	of	ADP
iajs-3524	203	12	osteoarthritis	osteoarthritis	NOUN
iajs-3524	203	13	—	—	PUNCT
iajs-3524	203	14	a	a	DET
iajs-3524	203	15	thorough	thorough	ADJ
iajs-3524	203	16	flow	flow	NOUN
iajs-3524	203	17	cytometry	cytometry	NOUN
iajs-3524	203	18	analysis	analysis	NOUN
iajs-3524	203	19	.	.	PUNCT
iajs-3524	204	1	life	life	NOUN
iajs-3524	204	2	2022	2022	NUM
iajs-3524	204	3	,	,	PUNCT
iajs-3524	204	4	12(11	12(11	NUM
iajs-3524	204	5	)	)	PUNCT
iajs-3524	204	6	,	,	PUNCT
iajs-3524	204	7	1938	1938	NUM
iajs-3524	204	8	.	.	PUNCT
iajs-3524	205	1	https://doi.org/10.3390/life12111938	https://doi.org/10.3390/life12111938	NOUN
iajs-3524	205	2	.	.	PUNCT
iajs-3524	206	1	10	10	NUM
iajs-3524	206	2	.	.	PUNCT
iajs-3524	207	1	xin	xin	PROPN
iajs-3524	207	2	,	,	PUNCT
iajs-3524	207	3	x.	x.	PROPN
iajs-3524	207	4	;	;	PUNCT
iajs-3524	207	5	tan	tan	PROPN
iajs-3524	207	6	,	,	PUNCT
iajs-3524	207	7	q.	q.	PROPN
iajs-3524	207	8	;	;	PUNCT
iajs-3524	207	9	li	li	PROPN
iajs-3524	207	10	,	,	PUNCT
iajs-3524	207	11	f.	f.	PROPN
iajs-3524	207	12	;	;	PUNCT
iajs-3524	207	13	chen	chen	PROPN
iajs-3524	207	14	,	,	PUNCT
iajs-3524	207	15	z.	z.	PROPN
iajs-3524	207	16	;	;	PUNCT
iajs-3524	207	17	zhang	zhang	PROPN
iajs-3524	207	18	,	,	PUNCT
iajs-3524	207	19	k.	k.	PROPN
iajs-3524	207	20	;	;	PUNCT
iajs-3524	207	21	li	li	PROPN
iajs-3524	207	22	,	,	PUNCT
iajs-3524	207	23	f.	f.	PROPN
iajs-3524	207	24	;	;	PUNCT
iajs-3524	207	25	yang	yang	PROPN
iajs-3524	207	26	,	,	PUNCT
iajs-3524	207	27	b.	b.	PROPN
iajs-3524	207	28	;	;	PUNCT
iajs-3524	207	29	xing	xing	PROPN
iajs-3524	207	30	,	,	PUNCT
iajs-3524	207	31	z.	z.	PROPN
iajs-3524	207	32	;	;	PUNCT
iajs-3524	207	33	zhou	zhou	PROPN
iajs-3524	207	34	,	,	PUNCT
iajs-3524	207	35	f.	f.	PROPN
iajs-3524	207	36	;	;	PUNCT
iajs-3524	207	37	tian	tian	PROPN
iajs-3524	207	38	,	,	PUNCT
iajs-3524	207	39	y.	y.	PROPN
iajs-3524	207	40	;	;	PUNCT
iajs-3524	207	41	lv	lv	PROPN
iajs-3524	207	42	,	,	PUNCT
iajs-3524	207	43	y.	y.	NOUN
iajs-3524	207	44	potential	potential	ADJ
iajs-3524	207	45	value	value	NOUN
iajs-3524	207	46	of	of	ADP
iajs-3524	207	47	matrix	matrix	NOUN
iajs-3524	207	48	metalloproteinase-13	metalloproteinase-13	PROPN
iajs-3524	207	49	as	as	ADP
iajs-3524	207	50	a	a	DET
iajs-3524	207	51	biomarker	biomarker	NOUN
iajs-3524	207	52	for	for	ADP
iajs-3524	207	53	osteoarthritis	osteoarthritis	NOUN
iajs-3524	207	54	.	.	PUNCT
iajs-3524	208	1	frontiers	frontier	NOUN
iajs-3524	208	2	in	in	ADP
iajs-3524	208	3	surgery	surgery	NOUN
iajs-3524	208	4	2021	2021	NUM
iajs-3524	208	5	,	,	PUNCT
iajs-3524	208	6	8(1	8(1	NOUN
iajs-3524	208	7	)	)	PUNCT
iajs-3524	208	8	,	,	PUNCT
iajs-3524	208	9	528	528	NUM
iajs-3524	208	10	.	.	PUNCT
iajs-3524	209	1	https://doi.org/10.3389/fsurg.2021.750047	https://doi.org/10.3389/fsurg.2021.750047	NOUN
iajs-3524	209	2	.	.	PUNCT
iajs-3524	210	1	11	11	NUM
iajs-3524	210	2	.	.	PUNCT
iajs-3524	211	1	hussein	hussein	PROPN
iajs-3524	211	2	,	,	PUNCT
iajs-3524	211	3	w.a	w.a	PROPN
iajs-3524	211	4	.	.	PROPN
iajs-3524	212	1	the	the	DET
iajs-3524	212	2	quality	quality	NOUN
iajs-3524	212	3	of	of	ADP
iajs-3524	212	4	life	life	NOUN
iajs-3524	212	5	in	in	ADP
iajs-3524	212	6	patients	patient	NOUN
iajs-3524	212	7	with	with	ADP
iajs-3524	212	8	rheumatoid	rheumatoid	NOUN
iajs-3524	212	9	arthritis	arthritis	NOUN
iajs-3524	212	10	in	in	ADP
iajs-3524	212	11	baghdad	baghdad	PROPN
iajs-3524	212	12	,	,	PUNCT
iajs-3524	212	13	2017	2017	NUM
iajs-3524	212	14	:	:	PUNCT
iajs-3524	212	15	a	a	DET
iajs-3524	212	16	crosssectional	crosssectional	ADJ
iajs-3524	212	17	study	study	NOUN
iajs-3524	212	18	.	.	PUNCT
iajs-3524	213	1	international	international	ADJ
iajs-3524	213	2	journal	journal	PROPN
iajs-3524	213	3	of	of	ADP
iajs-3524	213	4	medical	medical	ADJ
iajs-3524	213	5	research	research	NOUN
iajs-3524	213	6	and	and	CCONJ
iajs-3524	213	7	health	health	NOUN
iajs-3524	213	8	sciences	science	NOUN
iajs-3524	213	9	2017	2017	NUM
iajs-3524	213	10	,	,	PUNCT
iajs-3524	213	11	6(11	6(11	NUM
iajs-3524	213	12	)	)	PUNCT
iajs-3524	213	13	,	,	PUNCT
iajs-3524	213	14	20	20	NUM
iajs-3524	213	15	-	-	SYM
iajs-3524	213	16	34	34	NUM
iajs-3524	213	17	.	.	PUNCT
iajs-3524	214	1	https://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume	https://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume	PROPN
iajs-3524	214	2	.	.	PUNCT
iajs-3524	215	1	12	12	NUM
iajs-3524	215	2	.	.	PUNCT
iajs-3524	216	1	kang	kang	PROPN
iajs-3524	216	2	,	,	PUNCT
iajs-3524	216	3	e.h	e.h	PROPN
iajs-3524	216	4	.	.	PROPN
iajs-3524	216	5	;	;	PUNCT
iajs-3524	216	6	ha	ha	INTJ
iajs-3524	216	7	,	,	PUNCT
iajs-3524	216	8	y.j	y.j	PROPN
iajs-3524	216	9	.	.	PROPN
iajs-3524	216	10	;	;	PUNCT
iajs-3524	216	11	lee	lee	PROPN
iajs-3524	216	12	,	,	PUNCT
iajs-3524	216	13	y.j	y.j	PROPN
iajs-3524	216	14	.	.	PROPN
iajs-3524	216	15	autoantibody	autoantibody	ADJ
iajs-3524	216	16	biomarkers	biomarker	NOUN
iajs-3524	216	17	in	in	ADP
iajs-3524	216	18	rheumatic	rheumatic	ADJ
iajs-3524	216	19	diseases	disease	NOUN
iajs-3524	216	20	.	.	PUNCT
iajs-3524	217	1	international	international	ADJ
iajs-3524	217	2	journal	journal	NOUN
iajs-3524	217	3	of	of	ADP
iajs-3524	217	4	molecular	molecular	ADJ
iajs-3524	217	5	sciences	science	NOUN
iajs-3524	217	6	2020	2020	NUM
iajs-3524	217	7	,	,	PUNCT
iajs-3524	217	8	21(4	21(4	NUM
iajs-3524	217	9	)	)	PUNCT
iajs-3524	217	10	,	,	PUNCT
iajs-3524	217	11	1382	1382	NUM
iajs-3524	217	12	.	.	PUNCT
iajs-3524	218	1	https://doi.org/10.3390/ijms21041382	https://doi.org/10.3390/ijms21041382	PROPN
iajs-3524	218	2	.	.	PUNCT
iajs-3524	219	1	13	13	NUM
iajs-3524	219	2	.	.	X
iajs-3524	219	3	nazar	nazar	PROPN
iajs-3524	219	4	,	,	PUNCT
iajs-3524	219	5	l.	l.	PROPN
iajs-3524	219	6	;	;	PUNCT
iajs-3524	219	7	eiman	eiman	PROPN
iajs-3524	219	8	,	,	PUNCT
iajs-3524	219	9	a.a	a.a	PROPN
iajs-3524	219	10	.	.	PROPN
iajs-3524	219	11	study	study	NOUN
iajs-3524	219	12	of	of	ADP
iajs-3524	219	13	il-33	il-33	NOUN
iajs-3524	219	14	and	and	CCONJ
iajs-3524	219	15	il-1r4	il-1r4	NOUN
iajs-3524	219	16	in	in	ADP
iajs-3524	219	17	iraqi	iraqi	ADJ
iajs-3524	219	18	rheumatoid	rheumatoid	NOUN
iajs-3524	219	19	arthritis	arthritis	NOUN
iajs-3524	219	20	female	female	ADJ
iajs-3524	219	21	patient	patient	NOUN
iajs-3524	219	22	's	's	PART
iajs-3524	219	23	with	with	ADP
iajs-3524	219	24	and	and	CCONJ
iajs-3524	219	25	without	without	ADP
iajs-3524	219	26	dyslipidemia	dyslipidemia	NOUN
iajs-3524	219	27	prone	prone	ADJ
iajs-3524	219	28	to	to	ADP
iajs-3524	219	29	atherosclerosis	atherosclerosis	NOUN
iajs-3524	219	30	.	.	PUNCT
iajs-3524	220	1	ibn	ibn	PROPN
iajs-3524	220	2	al	al	PROPN
iajs-3524	220	3	-	-	PUNCT
iajs-3524	220	4	haitham	haitham	PROPN
iajs-3524	220	5	journal	journal	PROPN
iajs-3524	220	6	for	for	ADP
iajs-3524	220	7	pure	pure	ADJ
iajs-3524	220	8	and	and	CCONJ
iajs-3524	220	9	applied	applied	ADJ
iajs-3524	220	10	sciences	science	NOUN
iajs-3524	220	11	2019	2019	NUM
iajs-3524	220	12	,	,	PUNCT
iajs-3524	220	13	32(1	32(1	NUM
iajs-3524	220	14	)	)	PUNCT
iajs-3524	220	15	,	,	PUNCT
iajs-3524	220	16	48–56	48–56	NUM
iajs-3524	220	17	.	.	PUNCT
iajs-3524	221	1	https://doi.org/10.30526/32.1.1920	https://doi.org/10.30526/32.1.1920	NOUN
iajs-3524	221	2	.	.	PUNCT
iajs-3524	222	1	14	14	NUM
iajs-3524	222	2	.	.	X
iajs-3524	222	3	shapiro	shapiro	PROPN
iajs-3524	222	4	,	,	PUNCT
iajs-3524	222	5	s.c	s.c	PROPN
iajs-3524	222	6	.	.	PROPN
iajs-3524	222	7	biomarkers	biomarker	NOUN
iajs-3524	222	8	in	in	ADP
iajs-3524	222	9	rheumatoid	rheumatoid	NOUN
iajs-3524	222	10	arthritis	arthritis	NOUN
iajs-3524	222	11	.	.	PUNCT
iajs-3524	223	1	cureus	cureus	NOUN
iajs-3524	223	2	2021	2021	NUM
iajs-3524	223	3	,	,	PUNCT
iajs-3524	223	4	13(5	13(5	NUM
iajs-3524	223	5	)	)	PUNCT
iajs-3524	223	6	,	,	PUNCT
iajs-3524	223	7	e15063	e15063	NUM
iajs-3524	223	8	.	.	PUNCT
iajs-3524	223	9	https://doi.org/10.7759/cureus.15063	https://doi.org/10.7759/cureus.15063	NOUN
iajs-3524	223	10	.	.	PUNCT
iajs-3524	224	1	15	15	NUM
iajs-3524	224	2	.	.	PUNCT
iajs-3524	224	3	lee	lee	PROPN
iajs-3524	224	4	,	,	PUNCT
iajs-3524	224	5	y.h	y.h	PROPN
iajs-3524	224	6	.	.	PROPN
iajs-3524	224	7	;	;	PUNCT
iajs-3524	224	8	song	song	PROPN
iajs-3524	224	9	,	,	PUNCT
iajs-3524	224	10	g.g	g.g	PROPN
iajs-3524	224	11	.	.	PROPN
iajs-3524	224	12	causal	causal	PROPN
iajs-3524	224	13	association	association	PROPN
iajs-3524	224	14	between	between	ADP
iajs-3524	224	15	rheumatoid	rheumatoid	NOUN
iajs-3524	224	16	arthritis	arthritis	NOUN
iajs-3524	224	17	with	with	ADP
iajs-3524	224	18	the	the	DET
iajs-3524	224	19	increased	increase	VERB
iajs-3524	224	20	risk	risk	NOUN
iajs-3524	224	21	of	of	ADP
iajs-3524	224	22	type	type	NOUN
iajs-3524	224	23	2	2	NUM
iajs-3524	224	24	diabetes	diabetes	NOUN
iajs-3524	224	25	:	:	PUNCT
iajs-3524	224	26	a	a	DET
iajs-3524	224	27	mendelian	mendelian	ADJ
iajs-3524	224	28	randomization	randomization	NOUN
iajs-3524	224	29	analysis	analysis	NOUN
iajs-3524	224	30	.	.	PUNCT
iajs-3524	225	1	journal	journal	NOUN
iajs-3524	225	2	of	of	ADP
iajs-3524	225	3	rheumatic	rheumatic	ADJ
iajs-3524	225	4	diseases	disease	NOUN
iajs-3524	225	5	2019	2019	NUM
iajs-3524	225	6	,	,	PUNCT
iajs-3524	225	7	26(2	26(2	NUM
iajs-3524	225	8	)	)	PUNCT
iajs-3524	225	9	,	,	PUNCT
iajs-3524	225	10	131	131	NUM
iajs-3524	225	11	-	-	SYM
iajs-3524	225	12	136	136	NUM
iajs-3524	225	13	.	.	PUNCT
iajs-3524	226	1	https://doi.org/10.4078/jrd.2019.26.2.131	https://doi.org/10.4078/jrd.2019.26.2.131	PROPN
iajs-3524	226	2	.	.	PROPN
iajs-3524	226	3	16	16	NUM
iajs-3524	226	4	.	.	PUNCT
iajs-3524	227	1	tian	tian	PROPN
iajs-3524	227	2	,	,	PUNCT
iajs-3524	227	3	z.	z.	PROPN
iajs-3524	227	4	;	;	PUNCT
iajs-3524	227	5	mclaughlin	mclaughlin	PROPN
iajs-3524	227	6	,	,	PUNCT
iajs-3524	227	7	j.	j.	PROPN
iajs-3524	227	8	;	;	PUNCT
iajs-3524	227	9	verma	verma	PROPN
iajs-3524	227	10	,	,	PUNCT
iajs-3524	227	11	a.	a.	NOUN
iajs-3524	227	12	;	;	PUNCT
iajs-3524	227	13	chinoy	chinoy	PROPN
iajs-3524	227	14	,	,	PUNCT
iajs-3524	227	15	h.	h.	PROPN
iajs-3524	227	16	;	;	PUNCT
iajs-3524	227	17	heald	heald	PROPN
iajs-3524	227	18	,	,	PUNCT
iajs-3524	227	19	a.	a.	PROPN
iajs-3524	227	20	h.	h.	PROPN
iajs-3524	228	1	the	the	DET
iajs-3524	228	2	relationship	relationship	NOUN
iajs-3524	228	3	between	between	ADP
iajs-3524	228	4	rheumatoid	rheumatoid	NOUN
iajs-3524	228	5	arthritis	arthritis	NOUN
iajs-3524	228	6	and	and	CCONJ
iajs-3524	228	7	diabetes	diabetes	NOUN
iajs-3524	228	8	mellitus	mellitus	NOUN
iajs-3524	228	9	:	:	PUNCT
iajs-3524	228	10	a	a	DET
iajs-3524	228	11	systematic	systematic	ADJ
iajs-3524	228	12	review	review	NOUN
iajs-3524	228	13	and	and	CCONJ
iajs-3524	228	14	metaanalysis	metaanalysis	NOUN
iajs-3524	228	15	.	.	PUNCT
iajs-3524	229	1	cardiovascular	cardiovascular	ADJ
iajs-3524	229	2	endocrinology	endocrinology	NOUN
iajs-3524	229	3	and	and	CCONJ
iajs-3524	229	4	metabolism	metabolism	NOUN
iajs-3524	229	5	2021	2021	NUM
iajs-3524	229	6	,	,	PUNCT
iajs-3524	229	7	10(2	10(2	NUM
iajs-3524	229	8	)	)	PUNCT
iajs-3524	229	9	,	,	PUNCT
iajs-3524	229	10	125	125	NUM
iajs-3524	229	11	.	.	PUNCT
iajs-3524	230	1	https://doi.org/10.1097/xce.0000000000000244	https://doi.org/10.1097/xce.0000000000000244	INTJ
iajs-3524	230	2	.	.	PUNCT
iajs-3524	231	1	17	17	NUM
iajs-3524	231	2	.	.	PUNCT
iajs-3524	232	1	ahmad	ahmad	PROPN
iajs-3524	232	2	,	,	PUNCT
iajs-3524	232	3	r.	r.	PROPN
iajs-3524	232	4	;	;	PUNCT
iajs-3524	232	5	zgair	zgair	PROPN
iajs-3524	232	6	,	,	PUNCT
iajs-3524	232	7	a.	a.	NOUN
iajs-3524	232	8	immunological	immunological	ADJ
iajs-3524	232	9	and	and	CCONJ
iajs-3524	232	10	biological	biological	ADJ
iajs-3524	232	11	manifestation	manifestation	NOUN
iajs-3524	232	12	of	of	ADP
iajs-3524	232	13	rheumatoid	rheumatoid	NOUN
iajs-3524	232	14	arthritis	arthritis	NOUN
iajs-3524	232	15	patient	patient	NOUN
iajs-3524	232	16	in	in	ADP
iajs-3524	232	17	iraq	iraq	PROPN
iajs-3524	232	18	.	.	PUNCT
iajs-3524	233	1	indian	indian	PROPN
iajs-3524	233	2	journal	journal	PROPN
iajs-3524	233	3	of	of	ADP
iajs-3524	233	4	forensic	forensic	ADJ
iajs-3524	233	5	medicine	medicine	NOUN
iajs-3524	233	6	and	and	CCONJ
iajs-3524	233	7	toxicology	toxicology	NOUN
iajs-3524	233	8	2021	2021	NUM
iajs-3524	233	9	,	,	PUNCT
iajs-3524	233	10	15(4	15(4	NUM
iajs-3524	233	11	)	)	PUNCT
iajs-3524	233	12	,	,	PUNCT
iajs-3524	233	13	1344	1344	NUM
iajs-3524	233	14	-	-	SYM
iajs-3524	233	15	1350	1350	NUM
iajs-3524	233	16	.	.	PUNCT
iajs-3524	234	1	https://pdfs.semanticscholar.org/66ac/c786bd5ad9db2bb642a	https://pdfs.semanticscholar.org/66ac/c786bd5ad9db2bb642a	PROPN
iajs-3524	234	2	.	.	PROPN
iajs-3524	234	3	18	18	NUM
iajs-3524	234	4	.	.	PUNCT
iajs-3524	234	5	iwasaki	iwasaki	PROPN
iajs-3524	234	6	,	,	PUNCT
iajs-3524	234	7	t.	t.	PROPN
iajs-3524	234	8	;	;	PUNCT
iajs-3524	234	9	nakabo	nakabo	PROPN
iajs-3524	234	10	,	,	PUNCT
iajs-3524	234	11	s.	s.	PROPN
iajs-3524	234	12	;	;	PUNCT
iajs-3524	234	13	terao	terao	PROPN
iajs-3524	234	14	,	,	PUNCT
iajs-3524	234	15	c.	c.	PROPN
iajs-3524	234	16	;	;	PUNCT
iajs-3524	234	17	murakami	murakami	NOUN
iajs-3524	234	18	,	,	PUNCT
iajs-3524	234	19	k.	k.	PROPN
iajs-3524	234	20	;	;	PUNCT
iajs-3524	234	21	nakashima	nakashima	PROPN
iajs-3524	234	22	,	,	PUNCT
iajs-3524	234	23	r.	r.	PROPN
iajs-3524	234	24	;	;	PUNCT
iajs-3524	234	25	hashimoto	hashimoto	NOUN
iajs-3524	234	26	,	,	PUNCT
iajs-3524	234	27	m.	m.	NOUN
iajs-3524	234	28	;	;	PUNCT
iajs-3524	234	29	imura	imura	NOUN
iajs-3524	234	30	,	,	PUNCT
iajs-3524	234	31	y.	y.	PROPN
iajs-3524	234	32	;	;	PUNCT
iajs-3524	234	33	yukawa	yukawa	PROPN
iajs-3524	234	34	,	,	PUNCT
iajs-3524	234	35	n.	n.	PROPN
iajs-3524	234	36	;	;	PUNCT
iajs-3524	234	37	yoshifuji	yoshifuji	PROPN
iajs-3524	234	38	,	,	PUNCT
iajs-3524	234	39	h.	h.	PROPN
iajs-3524	234	40	;	;	PUNCT
iajs-3524	234	41	miura	miura	PROPN
iajs-3524	234	42	,	,	PUNCT
iajs-3524	234	43	y.	y.	PROPN
iajs-3524	234	44	;	;	PUNCT
iajs-3524	234	45	yurugi	yurugi	NOUN
iajs-3524	234	46	,	,	PUNCT
iajs-3524	234	47	k.	k.	PROPN
iajs-3524	234	48	;	;	PUNCT
iajs-3524	234	49	maekawa	maekawa	PROPN
iajs-3524	234	50	,	,	PUNCT
iajs-3524	234	51	t.	t.	PROPN
iajs-3524	234	52	;	;	PUNCT
iajs-3524	234	53	van	van	PROPN
iajs-3524	234	54	delft	delft	PROPN
iajs-3524	234	55	,	,	PUNCT
iajs-3524	234	56	m.	m.	NOUN
iajs-3524	234	57	a.	a.	NOUN
iajs-3524	234	58	m.	m.	PROPN
iajs-3524	234	59	;	;	PUNCT
iajs-3524	234	60	trouw	trouw	PROPN
iajs-3524	234	61	,	,	PUNCT
iajs-3524	234	62	l.a	l.a	PROPN
iajs-3524	234	63	.	.	PROPN
iajs-3524	234	64	;	;	PUNCT
iajs-3524	234	65	fujii	fujii	PROPN
iajs-3524	234	66	,	,	PUNCT
iajs-3524	234	67	t.	t.	PROPN
iajs-3524	234	68	;	;	PUNCT
iajs-3524	234	69	mimori	mimori	PROPN
iajs-3524	234	70	,	,	PUNCT
iajs-3524	234	71	t.	t.	PROPN
iajs-3524	234	72	;	;	PUNCT
iajs-3524	234	73	ohmura	ohmura	PROPN
iajs-3524	234	74	,	,	PUNCT
iajs-3524	234	75	k.	k.	PROPN
iajs-3524	234	76	long	long	ADJ
iajs-3524	234	77	-	-	PUNCT
iajs-3524	234	78	term	term	NOUN
iajs-3524	234	79	follow	follow	NOUN
iajs-3524	234	80	-	-	PUNCT
iajs-3524	234	81	up	up	NOUN
iajs-3524	234	82	of	of	ADP
iajs-3524	234	83	patients	patient	NOUN
iajs-3524	234	84	with	with	ADP
iajs-3524	234	85	anti	anti	ADJ
iajs-3524	234	86	-	-	ADJ
iajs-3524	234	87	cyclic	cyclic	ADJ
iajs-3524	234	88	citrullinated	citrullinate	VERB
iajs-3524	234	89	peptide	peptide	NOUN
iajs-3524	234	90	antibody	antibody	NOUN
iajs-3524	234	91	-	-	PUNCT
iajs-3524	234	92	positive	positive	ADJ
iajs-3524	234	93	connective	connective	ADJ
iajs-3524	234	94	tissue	tissue	NOUN
iajs-3524	234	95	disease	disease	NOUN
iajs-3524	234	96	:	:	PUNCT
iajs-3524	234	97	a	a	DET
iajs-3524	234	98	retrospective	retrospective	ADJ
iajs-3524	234	99	observational	observational	ADJ
iajs-3524	234	100	study	study	NOUN
iajs-3524	234	101	including	include	VERB
iajs-3524	234	102	information	information	NOUN
iajs-3524	234	103	on	on	ADP
iajs-3524	234	104	the	the	DET
iajs-3524	234	105	hla	hla	PROPN
iajs-3524	234	106	-	-	PUNCT
iajs-3524	234	107	drb1	drb1	NOUN
iajs-3524	234	108	allele	allele	NOUN
iajs-3524	234	109	and	and	CCONJ
iajs-3524	234	110	citrullination	citrullination	NOUN
iajs-3524	234	111	dependency	dependency	NOUN
iajs-3524	234	112	.	.	PUNCT
iajs-3524	235	1	arthritis	arthritis	NOUN
iajs-3524	235	2	research	research	NOUN
iajs-3524	235	3	and	and	CCONJ
iajs-3524	235	4	therapy	therapy	NOUN
iajs-3524	235	5	2020	2020	NUM
iajs-3524	235	6	,	,	PUNCT
iajs-3524	235	7	22(1	22(1	NUM
iajs-3524	235	8	)	)	PUNCT
iajs-3524	235	9	,	,	PUNCT
iajs-3524	235	10	1	1	NUM
iajs-3524	235	11	-	-	SYM
iajs-3524	235	12	9	9	NUM
iajs-3524	235	13	.	.	PUNCT
iajs-3524	235	14	https://doi.org/10.1186/s13075-020-02351-4	https://doi.org/10.1186/s13075-020-02351-4	NUM
iajs-3524	235	15	.	.	PUNCT
iajs-3524	236	1	19	19	NUM
iajs-3524	236	2	.	.	X
iajs-3524	236	3	khidhir	khidhir	PROPN
iajs-3524	236	4	,	,	PUNCT
iajs-3524	236	5	r.m	r.m	PROPN
iajs-3524	236	6	.	.	PROPN
iajs-3524	236	7	;	;	PUNCT
iajs-3524	236	8	al	al	PROPN
iajs-3524	236	9	-	-	PUNCT
iajs-3524	236	10	jubouri	jubouri	PROPN
iajs-3524	236	11	,	,	PUNCT
iajs-3524	236	12	r.h	r.h	PROPN
iajs-3524	236	13	.	.	PUNCT
iajs-3524	237	1	the	the	DET
iajs-3524	237	2	study	study	NOUN
iajs-3524	237	3	of	of	ADP
iajs-3524	237	4	tempromandibularjoint	tempromandibularjoint	ADJ
iajs-3524	237	5	disorders	disorder	NOUN
iajs-3524	237	6	and	and	CCONJ
iajs-3524	237	7	anti	anti	ADJ
iajs-3524	237	8	-	-	ADJ
iajs-3524	237	9	cyclic	cyclic	ADJ
iajs-3524	237	10	citrullinated	citrullinate	VERB
iajs-3524	237	11	peptide	peptide	NOUN
iajs-3524	237	12	antibodies	antibodie	VERB
iajs-3524	237	13	in	in	ADP
iajs-3524	237	14	serum	serum	NOUN
iajs-3524	237	15	and	and	CCONJ
iajs-3524	237	16	saliva	saliva	NOUN
iajs-3524	237	17	of	of	ADP
iajs-3524	237	18	patients	patient	NOUN
iajs-3524	237	19	with	with	ADP
iajs-3524	237	20	rheumatoid	rheumatoid	NOUN
iajs-3524	237	21	arthritis	arthritis	NOUN
iajs-3524	237	22	.	.	PUNCT
iajs-3524	238	1	journal	journal	PROPN
iajs-3524	238	2	of	of	ADP
iajs-3524	238	3	baghdad	baghdad	PROPN
iajs-3524	238	4	college	college	PROPN
iajs-3524	238	5	of	of	ADP
iajs-3524	238	6	dentistry	dentistry	NOUN
iajs-3524	238	7	2013	2013	NUM
iajs-3524	238	8	,	,	PUNCT
iajs-3524	238	9	25(special	25(special	NUM
iajs-3524	238	10	is	be	AUX
iajs-3524	238	11	)	)	PUNCT
iajs-3524	238	12	,	,	PUNCT
iajs-3524	238	13	67	67	NUM
iajs-3524	238	14	-	-	SYM
iajs-3524	238	15	71	71	NUM
iajs-3524	238	16	.	.	PUNCT
iajs-3524	239	1	https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/201	https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/201	NOUN
iajs-3524	239	2	.	.	PUNCT
iajs-3524	240	1	20	20	NUM
iajs-3524	240	2	.	.	X
iajs-3524	241	1	haydar	haydar	PROPN
iajs-3524	241	2	,	,	PUNCT
iajs-3524	241	3	a.a	a.a	PROPN
iajs-3524	241	4	.	.	PROPN
iajs-3524	241	5	;	;	PUNCT
iajs-3524	241	6	abdullah	abdullah	PROPN
iajs-3524	241	7	,	,	PUNCT
iajs-3524	241	8	i.r	i.r	PROPN
iajs-3524	241	9	.	.	PUNCT
iajs-3524	242	1	the	the	DET
iajs-3524	242	2	impact	impact	NOUN
iajs-3524	242	3	of	of	ADP
iajs-3524	242	4	therapies	therapy	NOUN
iajs-3524	242	5	as	as	ADP
iajs-3524	242	6	monotherapy	monotherapy	NOUN
iajs-3524	242	7	with	with	ADP
iajs-3524	242	8	combined	combined	ADJ
iajs-3524	242	9	therapy	therapy	NOUN
iajs-3524	242	10	on	on	ADP
iajs-3524	242	11	novel	novel	NOUN
iajs-3524	242	12	and	and	CCONJ
iajs-3524	242	13	traditional	traditional	ADJ
iajs-3524	242	14	biomarkers	biomarker	NOUN
iajs-3524	242	15	in	in	ADP
iajs-3524	242	16	patients	patient	NOUN
iajs-3524	242	17	with	with	ADP
iajs-3524	242	18	rheumatoid	rheumatoid	NOUN
iajs-3524	242	19	arthritis	arthritis	NOUN
iajs-3524	242	20	.	.	PUNCT
iajs-3524	243	1	zanco	zanco	PROPN
iajs-3524	243	2	journal	journal	PROPN
iajs-3524	243	3	of	of	ADP
iajs-3524	243	4	medical	medical	ADJ
iajs-3524	243	5	sciences	science	NOUN
iajs-3524	243	6	2020	2020	NUM
iajs-3524	243	7	,	,	PUNCT
iajs-3524	243	8	24(3	24(3	NUM
iajs-3524	243	9	)	)	PUNCT
iajs-3524	243	10	,	,	PUNCT
iajs-3524	243	11	325	325	NUM
iajs-3524	243	12	-	-	SYM
iajs-3524	243	13	332	332	NUM
iajs-3524	243	14	.	.	PUNCT
iajs-3524	244	1	https://doi.org/10.15218/zjms.2020.038	https://doi.org/10.15218/zjms.2020.038	PROPN
iajs-3524	244	2	.	.	PUNCT
iajs-3524	245	1	21	21	NUM
iajs-3524	245	2	.	.	X
iajs-3524	246	1	oliveira	oliveira	PROPN
iajs-3524	246	2	,	,	PUNCT
iajs-3524	246	3	t.h.c	t.h.c	PROPN
iajs-3524	246	4	.	.	PUNCT
iajs-3524	246	5	;	;	PUNCT
iajs-3524	246	6	marques	marques	PROPN
iajs-3524	246	7	,	,	PUNCT
iajs-3524	246	8	p.e	p.e	PROPN
iajs-3524	246	9	.	.	PROPN
iajs-3524	246	10	;	;	PUNCT
iajs-3524	246	11	proost	proost	ADV
iajs-3524	246	12	,	,	PUNCT
iajs-3524	246	13	p.	p.	PROPN
iajs-3524	246	14	;	;	PUNCT
iajs-3524	246	15	teixeira	teixeira	PROPN
iajs-3524	246	16	,	,	PUNCT
iajs-3524	246	17	m.m.m	m.m.m	INTJ
iajs-3524	246	18	.	.	PUNCT
iajs-3524	247	1	neutrophils	neutrophil	NOUN
iajs-3524	247	2	:	:	PUNCT
iajs-3524	247	3	a	a	DET
iajs-3524	247	4	cornerstone	cornerstone	NOUN
iajs-3524	247	5	of	of	ADP
iajs-3524	247	6	liver	liver	NOUN
iajs-3524	247	7	ischemia	ischemia	NOUN
iajs-3524	247	8	and	and	CCONJ
iajs-3524	247	9	reperfusion	reperfusion	NOUN
iajs-3524	247	10	injury	injury	NOUN
iajs-3524	247	11	.	.	PUNCT
iajs-3524	248	1	laboratory	laboratory	NOUN
iajs-3524	248	2	investigation	investigation	NOUN
iajs-3524	248	3	2018	2018	NUM
iajs-3524	248	4	,	,	PUNCT
iajs-3524	248	5	98(1	98(1	NOUN
iajs-3524	248	6	)	)	PUNCT
iajs-3524	248	7	,	,	PUNCT
iajs-3524	248	8	51–62	51–62	NUM
iajs-3524	248	9	.	.	PUNCT
iajs-3524	249	1	https://doi.org/10.1038/labinvest.2017.90	https://doi.org/10.1038/labinvest.2017.90	PROPN
iajs-3524	249	2	.	.	PUNCT
iajs-3524	250	1	22	22	NUM
iajs-3524	250	2	.	.	PUNCT
iajs-3524	251	1	jabłońska	jabłońska	ADJ
iajs-3524	251	2	-	-	PUNCT
iajs-3524	251	3	trypuć	trypuć	ADJ
iajs-3524	251	4	,	,	PUNCT
iajs-3524	251	5	a.	a.	NOUN
iajs-3524	251	6	;	;	PUNCT
iajs-3524	251	7	matejczyk	matejczyk	NOUN
iajs-3524	251	8	,	,	PUNCT
iajs-3524	251	9	m.	m.	NOUN
iajs-3524	251	10	;	;	PUNCT
iajs-3524	251	11	rosochacki	rosochacki	PROPN
iajs-3524	251	12	,	,	PUNCT
iajs-3524	251	13	s.	s.	PROPN
iajs-3524	251	14	matrix	matrix	VERB
iajs-3524	251	15	metalloproteinases	metalloproteinase	NOUN
iajs-3524	251	16	(	(	PUNCT
iajs-3524	251	17	mmps	mmp	NOUN
iajs-3524	251	18	)	)	PUNCT
iajs-3524	251	19	,	,	PUNCT
iajs-3524	251	20	the	the	DET
iajs-3524	251	21	main	main	ADJ
iajs-3524	251	22	extracellular	extracellular	ADJ
iajs-3524	251	23	matrix	matrix	NOUN
iajs-3524	251	24	(	(	PUNCT
iajs-3524	251	25	ecm	ecm	NOUN
iajs-3524	251	26	)	)	PUNCT
iajs-3524	251	27	enzymes	enzyme	NOUN
iajs-3524	251	28	in	in	ADP
iajs-3524	251	29	collagen	collagen	NOUN
iajs-3524	251	30	degradation	degradation	NOUN
iajs-3524	251	31	,	,	PUNCT
iajs-3524	251	32	as	as	ADP
iajs-3524	251	33	a	a	DET
iajs-3524	251	34	target	target	NOUN
iajs-3524	251	35	for	for	ADP
iajs-3524	251	36	anticancer	anticancer	NOUN
iajs-3524	251	37	drugs	drug	NOUN
iajs-3524	251	38	.	.	PUNCT
iajs-3524	252	1	journal	journal	NOUN
iajs-3524	252	2	of	of	ADP
iajs-3524	252	3	enzyme	enzyme	NOUN
iajs-3524	252	4	inhibition	inhibition	NOUN
iajs-3524	252	5	and	and	CCONJ
iajs-3524	252	6	medicinal	medicinal	ADJ
iajs-3524	252	7	chemistry	chemistry	NOUN
iajs-3524	252	8	2016	2016	NUM
iajs-3524	252	9	,	,	PUNCT
iajs-3524	252	10	31(1	31(1	NUM
iajs-3524	252	11	)	)	PUNCT
iajs-3524	252	12	,	,	PUNCT
iajs-3524	252	13	177–183	177–183	NUM
iajs-3524	252	14	.	.	PUNCT
iajs-3524	253	1	https://doi.org/10.3109/14756366.2016.1161620	https://doi.org/10.3109/14756366.2016.1161620	PROPN
iajs-3524	253	2	.	.	PUNCT
iajs-3524	254	1	https://europepmc.org/article/med/9166290	https://europepmc.org/article/med/9166290	PROPN
iajs-3524	254	2	https://doi.org/10.3390/life12111938	https://doi.org/10.3390/life12111938	NOUN
iajs-3524	254	3	https://doi.org/10.3389/fsurg.2021.750047	https://doi.org/10.3389/fsurg.2021.750047	PROPN
iajs-3524	254	4	https://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume	https://www.indianjournals.com/ijor.aspx?target=ijor:ijmrhs&volume	ADJ
iajs-3524	254	5	https://doi.org/10.3390/ijms21041382	https://doi.org/10.3390/ijms21041382	PROPN
iajs-3524	254	6	https://doi.org/10.30526/32.1.1920	https://doi.org/10.30526/32.1.1920	PROPN
iajs-3524	254	7	https://doi.org/10.7759/cureus.15063	https://doi.org/10.7759/cureus.15063	NOUN
iajs-3524	254	8	.	.	PUNCT
iajs-3524	255	1	https://doi.org/10.4078/jrd.2019.26.2.131	https://doi.org/10.4078/jrd.2019.26.2.131	PROPN
iajs-3524	256	1	https://doi.org/10.1097/xce.0000000000000244	https://doi.org/10.1097/xce.0000000000000244	PROPN
iajs-3524	256	2	https://pdfs.semanticscholar.org/66ac/c786bd5ad9db2bb642a	https://pdfs.semanticscholar.org/66ac/c786bd5ad9db2bb642a	PROPN
iajs-3524	256	3	https://doi.org/10.1186/s13075-020-02351-4	https://doi.org/10.1186/s13075-020-02351-4	NUM
iajs-3524	256	4	https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/201	https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/201	NOUN
iajs-3524	256	5	https://doi.org/10.15218/zjms.2020.038	https://doi.org/10.15218/zjms.2020.038	PROPN
iajs-3524	256	6	https://doi.org/10.1038/labinvest.2017.90	https://doi.org/10.1038/labinvest.2017.90	PROPN
iajs-3524	256	7	https://doi.org/10.3109/14756366.2016.1161620	https://doi.org/10.3109/14756366.2016.1161620	PROPN
iajs-3524	256	8	ihjpas	ihjpas	PROPN
iajs-3524	256	9	.	.	PUNCT
iajs-3524	257	1	2024	2024	NUM
iajs-3524	257	2	,	,	PUNCT
iajs-3524	257	3	37(4	37(4	PROPN
iajs-3524	257	4	)	)	PUNCT
iajs-3524	257	5	295	295	NUM
iajs-3524	257	6	23	23	NUM
iajs-3524	257	7	.	.	PUNCT
iajs-3524	258	1	luo	luo	PROPN
iajs-3524	258	2	,	,	PUNCT
iajs-3524	258	3	s.	s.	PROPN
iajs-3524	258	4	;	;	PUNCT
iajs-3524	258	5	li	li	PROPN
iajs-3524	258	6	,	,	PUNCT
iajs-3524	258	7	w.	w.	PROPN
iajs-3524	258	8	;	;	PUNCT
iajs-3524	258	9	wu	wu	PROPN
iajs-3524	258	10	,	,	PUNCT
iajs-3524	258	11	w.	w.	PROPN
iajs-3524	258	12	;	;	PUNCT
iajs-3524	258	13	shi	shi	PROPN
iajs-3524	258	14	,	,	PUNCT
iajs-3524	258	15	q.	q.	PROPN
iajs-3524	258	16	elevated	elevate	VERB
iajs-3524	258	17	expression	expression	NOUN
iajs-3524	258	18	of	of	ADP
iajs-3524	258	19	mmp8	mmp8	PROPN
iajs-3524	258	20	and	and	CCONJ
iajs-3524	258	21	mmp9	mmp9	PROPN
iajs-3524	258	22	contributes	contribute	VERB
iajs-3524	258	23	to	to	ADP
iajs-3524	258	24	diabetic	diabetic	ADJ
iajs-3524	258	25	osteoarthritis	osteoarthritis	NOUN
iajs-3524	258	26	progression	progression	NOUN
iajs-3524	258	27	in	in	ADP
iajs-3524	258	28	a	a	DET
iajs-3524	258	29	rat	rat	NOUN
iajs-3524	258	30	model	model	NOUN
iajs-3524	258	31	.	.	PUNCT
iajs-3524	259	1	journal	journal	PROPN
iajs-3524	259	2	of	of	ADP
iajs-3524	259	3	orthopaedic	orthopaedic	ADJ
iajs-3524	259	4	surgery	surgery	NOUN
iajs-3524	259	5	and	and	CCONJ
iajs-3524	259	6	research	research	NOUN
iajs-3524	259	7	2021	2021	NUM
iajs-3524	259	8	,	,	PUNCT
iajs-3524	259	9	16(1),1	16(1),1	PROPN
iajs-3524	259	10	-	-	SYM
iajs-3524	259	11	9	9	NUM
iajs-3524	259	12	.	.	PUNCT
iajs-3524	260	1	https://doi.org/10.1186/s13018-021-02208-9	https://doi.org/10.1186/s13018-021-02208-9	NUM
iajs-3524	260	2	.	.	PUNCT
iajs-3524	261	1	24	24	NUM
iajs-3524	261	2	.	.	PUNCT
iajs-3524	262	1	wilkinson	wilkinson	PROPN
iajs-3524	262	2	,	,	PUNCT
iajs-3524	262	3	d.j	d.j	PROPN
iajs-3524	262	4	.	.	PROPN
iajs-3524	262	5	;	;	PUNCT
iajs-3524	262	6	falconer	falconer	NOUN
iajs-3524	262	7	,	,	PUNCT
iajs-3524	262	8	a.m.	a.m.	PROPN
iajs-3524	262	9	;	;	PUNCT
iajs-3524	262	10	wright	wright	PROPN
iajs-3524	262	11	,	,	PUNCT
iajs-3524	262	12	h.l	h.l	PROPN
iajs-3524	262	13	.	.	PROPN
iajs-3524	262	14	;	;	PUNCT
iajs-3524	262	15	lin	lin	PROPN
iajs-3524	262	16	,	,	PUNCT
iajs-3524	262	17	h.	h.	PROPN
iajs-3524	262	18	;	;	PUNCT
iajs-3524	262	19	yamamoto	yamamoto	PROPN
iajs-3524	262	20	,	,	PUNCT
iajs-3524	262	21	k.	k.	PROPN
iajs-3524	262	22	;	;	PUNCT
iajs-3524	262	23	cheung	cheung	PROPN
iajs-3524	262	24	,	,	PUNCT
iajs-3524	262	25	k.	k.	PROPN
iajs-3524	262	26	;	;	PUNCT
iajs-3524	262	27	charlton	charlton	PROPN
iajs-3524	262	28	,	,	PUNCT
iajs-3524	262	29	s.h	s.h	PROPN
iajs-3524	262	30	.	.	PROPN
iajs-3524	262	31	;	;	PUNCT
iajs-3524	262	32	arques	arques	PROPN
iajs-3524	262	33	,	,	PUNCT
iajs-3524	262	34	m.d.c	m.d.c	PROPN
iajs-3524	262	35	.	.	PROPN
iajs-3524	262	36	;	;	PUNCT
iajs-3524	262	37	janciauskiene	janciauskiene	PROPN
iajs-3524	262	38	,	,	PUNCT
iajs-3524	262	39	s.	s.	PROPN
iajs-3524	262	40	;	;	PUNCT
iajs-3524	262	41	refaie	refaie	PROPN
iajs-3524	262	42	,	,	PUNCT
iajs-3524	262	43	r.	r.	PROPN
iajs-3524	262	44	;	;	PUNCT
iajs-3524	262	45	rankin	rankin	PROPN
iajs-3524	262	46	,	,	PUNCT
iajs-3524	262	47	k.s	k.s	PROPN
iajs-3524	262	48	.	.	PROPN
iajs-3524	262	49	matrix	matrix	NOUN
iajs-3524	262	50	metalloproteinase‐13	metalloproteinase‐13	PROPN
iajs-3524	262	51	is	be	AUX
iajs-3524	262	52	fully	fully	ADV
iajs-3524	262	53	activated	activate	VERB
iajs-3524	262	54	by	by	ADP
iajs-3524	262	55	neutrophil	neutrophil	ADJ
iajs-3524	262	56	elastase	elastase	NOUN
iajs-3524	262	57	and	and	CCONJ
iajs-3524	262	58	inactivates	inactivate	VERB
iajs-3524	262	59	its	its	PRON
iajs-3524	262	60	serpin	serpin	PROPN
iajs-3524	262	61	inhibitor	inhibitor	NOUN
iajs-3524	262	62	,	,	PUNCT
iajs-3524	262	63	alpha‐1	alpha‐1	DET
iajs-3524	262	64	antitrypsin	antitrypsin	NOUN
iajs-3524	262	65	:	:	PUNCT
iajs-3524	262	66	implications	implication	NOUN
iajs-3524	262	67	for	for	ADP
iajs-3524	262	68	osteoarthritis	osteoarthritis	NOUN
iajs-3524	262	69	.	.	PUNCT
iajs-3524	263	1	the	the	DET
iajs-3524	263	2	febs	febs	NOUN
iajs-3524	263	3	journal	journal	PROPN
iajs-3524	263	4	2022	2022	NUM
iajs-3524	263	5	,	,	PUNCT
iajs-3524	263	6	289(1	289(1	NUM
iajs-3524	263	7	)	)	PUNCT
iajs-3524	263	8	,	,	PUNCT
iajs-3524	263	9	121	121	NUM
iajs-3524	263	10	-	-	SYM
iajs-3524	263	11	139	139	NUM
iajs-3524	263	12	.	.	PUNCT
iajs-3524	263	13	https://doi.org/10.1111/febs.16127	https://doi.org/10.1111/febs.16127	NOUN
iajs-3524	263	14	.	.	PUNCT
iajs-3524	264	1	25	25	NUM
iajs-3524	264	2	.	.	X
iajs-3524	264	3	fosang	fosang	PROPN
iajs-3524	264	4	,	,	PUNCT
iajs-3524	264	5	a.j	a.j	PROPN
iajs-3524	264	6	.	.	PROPN
iajs-3524	264	7	;	;	PUNCT
iajs-3524	264	8	last	last	ADJ
iajs-3524	264	9	,	,	PUNCT
iajs-3524	264	10	k.	k.	PROPN
iajs-3524	264	11	;	;	PUNCT
iajs-3524	264	12	knauper	knauper	NOUN
iajs-3524	264	13	,	,	PUNCT
iajs-3524	264	14	v.	v.	PROPN
iajs-3524	264	15	;	;	PUNCT
iajs-3524	264	16	murphy	murphy	PROPN
iajs-3524	264	17	,	,	PUNCT
iajs-3524	264	18	g.	g.	PROPN
iajs-3524	264	19	;	;	PUNCT
iajs-3524	264	20	neame	neame	PROPN
iajs-3524	264	21	,	,	PUNCT
iajs-3524	264	22	p.j	p.j	PROPN
iajs-3524	264	23	.	.	PROPN
iajs-3524	264	24	degradation	degradation	NOUN
iajs-3524	264	25	of	of	ADP
iajs-3524	264	26	cartilage	cartilage	NOUN
iajs-3524	264	27	aggrecan	aggrecan	ADJ
iajs-3524	264	28	by	by	ADP
iajs-3524	264	29	collagenase-3	collagenase-3	PROPN
iajs-3524	264	30	(	(	PUNCT
iajs-3524	264	31	mmp-13	mmp-13	NOUN
iajs-3524	264	32	)	)	PUNCT
iajs-3524	264	33	.	.	PUNCT
iajs-3524	265	1	febs	febs	NOUN
iajs-3524	265	2	letters	letter	NOUN
iajs-3524	265	3	1996	1996	NUM
iajs-3524	265	4	,	,	PUNCT
iajs-3524	265	5	380(1	380(1	NUM
iajs-3524	265	6	-	-	SYM
iajs-3524	265	7	2	2	NUM
iajs-3524	265	8	)	)	PUNCT
iajs-3524	265	9	,	,	PUNCT
iajs-3524	265	10	17	17	NUM
iajs-3524	265	11	-	-	SYM
iajs-3524	265	12	20	20	NUM
iajs-3524	265	13	.	.	PUNCT
iajs-3524	266	1	https://doi.org/10.1016/00145793(95)01539-6	https://doi.org/10.1016/00145793(95)01539-6	ADJ
iajs-3524	266	2	.	.	PUNCT
iajs-3524	267	1	26	26	NUM
iajs-3524	267	2	.	.	PUNCT
iajs-3524	268	1	li	li	PROPN
iajs-3524	268	2	,	,	PUNCT
iajs-3524	268	3	n.g	n.g	PROPN
iajs-3524	268	4	.	.	PROPN
iajs-3524	268	5	;	;	PUNCT
iajs-3524	268	6	shi	shi	PROPN
iajs-3524	268	7	,	,	PUNCT
iajs-3524	268	8	z.h	z.h	PROPN
iajs-3524	268	9	.	.	PROPN
iajs-3524	268	10	;	;	PUNCT
iajs-3524	268	11	tang	tang	PROPN
iajs-3524	268	12	,	,	PUNCT
iajs-3524	268	13	y.p	y.p	PROPN
iajs-3524	268	14	.	.	PROPN
iajs-3524	268	15	;	;	PUNCT
iajs-3524	268	16	wang	wang	PROPN
iajs-3524	268	17	,	,	PUNCT
iajs-3524	268	18	z.j	z.j	PROPN
iajs-3524	268	19	.	.	PROPN
iajs-3524	268	20	;	;	PUNCT
iajs-3524	268	21	song	song	NOUN
iajs-3524	268	22	,	,	PUNCT
iajs-3524	268	23	s.l	s.l	PROPN
iajs-3524	268	24	.	.	PROPN
iajs-3524	268	25	;	;	PUNCT
iajs-3524	268	26	qian	qian	PROPN
iajs-3524	268	27	,	,	PUNCT
iajs-3524	268	28	l.h	l.h	PROPN
iajs-3524	268	29	.	.	PROPN
iajs-3524	268	30	;	;	PUNCT
iajs-3524	269	1	qian	qian	PROPN
iajs-3524	269	2	,	,	PUNCT
iajs-3524	269	3	d.w	d.w	PROPN
iajs-3524	269	4	.	.	PROPN
iajs-3524	269	5	;	;	PUNCT
iajs-3524	269	6	duan	duan	PROPN
iajs-3524	269	7	,	,	PUNCT
iajs-3524	269	8	j.a	j.a	PROPN
iajs-3524	269	9	.	.	PROPN
iajs-3524	269	10	new	new	PROPN
iajs-3524	269	11	hope	hope	NOUN
iajs-3524	269	12	for	for	ADP
iajs-3524	269	13	the	the	DET
iajs-3524	269	14	treatment	treatment	NOUN
iajs-3524	269	15	of	of	ADP
iajs-3524	269	16	osteoarthritis	osteoarthritis	NOUN
iajs-3524	269	17	through	through	ADP
iajs-3524	269	18	selectiveinhibition	selectiveinhibition	NOUN
iajs-3524	269	19	of	of	ADP
iajs-3524	269	20	mmp-13	mmp-13	PROPN
iajs-3524	269	21	.	.	PUNCT
iajs-3524	269	22	current	current	ADJ
iajs-3524	269	23	medicinal	medicinal	ADJ
iajs-3524	269	24	chemistry	chemistry	NOUN
iajs-3524	269	25	2011	2011	NUM
iajs-3524	269	26	,	,	PUNCT
iajs-3524	269	27	18(7	18(7	NUM
iajs-3524	269	28	)	)	PUNCT
iajs-3524	269	29	,	,	PUNCT
iajs-3524	269	30	977–1001	977–1001	X
iajs-3524	269	31	.	.	PUNCT
iajs-3524	269	32	https://doi.org/10.2174/092986711794940905	https://doi.org/10.2174/092986711794940905	VERB
iajs-3524	269	33	.	.	PUNCT
iajs-3524	270	1	27	27	NUM
iajs-3524	270	2	.	.	PUNCT
iajs-3524	271	1	nasr	nasr	PROPN
iajs-3524	271	2	,	,	PUNCT
iajs-3524	271	3	m.h	m.h	PROPN
iajs-3524	271	4	.	.	PROPN
iajs-3524	271	5	;	;	PUNCT
iajs-3524	271	6	hassan	hassan	PROPN
iajs-3524	271	7	,	,	PUNCT
iajs-3524	271	8	b.a.r	b.a.r	NOUN
iajs-3524	271	9	.	.	PUNCT
iajs-3524	271	10	;	;	PUNCT
iajs-3524	271	11	othman	othman	PROPN
iajs-3524	271	12	,	,	PUNCT
iajs-3524	271	13	n.	n.	PROPN
iajs-3524	271	14	;	;	PUNCT
iajs-3524	271	15	karuppannan	karuppannan	PROPN
iajs-3524	271	16	,	,	PUNCT
iajs-3524	271	17	m.	m.	NOUN
iajs-3524	271	18	;	;	PUNCT
iajs-3524	271	19	abdulaziz	abdulaziz	PROPN
iajs-3524	271	20	,	,	PUNCT
iajs-3524	271	21	n.b	n.b	PROPN
iajs-3524	271	22	.	.	PROPN
iajs-3524	271	23	;	;	PUNCT
iajs-3524	271	24	mohammed	mohammed	PROPN
iajs-3524	271	25	,	,	PUNCT
iajs-3524	271	26	a.h	a.h	PROPN
iajs-3524	271	27	.	.	PROPN
iajs-3524	271	28	;	;	PUNCT
iajs-3524	271	29	alsarani	alsarani	PROPN
iajs-3524	271	30	,	,	PUNCT
iajs-3524	271	31	m.a	m.a	PROPN
iajs-3524	271	32	.	.	PROPN
iajs-3524	271	33	;	;	PUNCT
iajs-3524	271	34	eskembaji	eskembaji	PROPN
iajs-3524	271	35	,	,	PUNCT
iajs-3524	271	36	m.h	m.h	PROPN
iajs-3524	271	37	.	.	PROPN
iajs-3524	271	38	;	;	PUNCT
iajs-3524	271	39	aman	aman	NOUN
iajs-3524	271	40	,	,	PUNCT
iajs-3524	271	41	a.m.	a.m.	ADV
iajs-3524	271	42	;	;	PUNCT
iajs-3524	271	43	othman	othman	PROPN
iajs-3524	271	44	,	,	PUNCT
iajs-3524	271	45	g.	g.	PROPN
iajs-3524	271	46	prevalence	prevalence	NOUN
iajs-3524	271	47	of	of	ADP
iajs-3524	271	48	vitamin	vitamin	NOUN
iajs-3524	271	49	d	d	NOUN
iajs-3524	271	50	deficiency	deficiency	NOUN
iajs-3524	271	51	between	between	ADP
iajs-3524	271	52	type	type	NOUN
iajs-3524	271	53	2	2	NUM
iajs-3524	271	54	diabetes	diabetes	NOUN
iajs-3524	271	55	mellitus	mellitus	NOUN
iajs-3524	271	56	patients	patient	NOUN
iajs-3524	271	57	and	and	CCONJ
iajs-3524	271	58	non	non	NOUN
iajs-3524	271	59	-	-	NOUN
iajs-3524	271	60	diabetics	diabetic	NOUN
iajs-3524	271	61	in	in	ADP
iajs-3524	271	62	the	the	DET
iajs-3524	271	63	arab	arab	PROPN
iajs-3524	271	64	gulf	gulf	PROPN
iajs-3524	271	65	.	.	PUNCT
iajs-3524	272	1	diabetes	diabetes	NOUN
iajs-3524	272	2	,	,	PUNCT
iajs-3524	272	3	metabolic	metabolic	NOUN
iajs-3524	272	4	syndrome	syndrome	NOUN
iajs-3524	272	5	and	and	CCONJ
iajs-3524	272	6	obesity	obesity	NOUN
iajs-3524	272	7	:	:	PUNCT
iajs-3524	272	8	targets	target	NOUN
iajs-3524	272	9	and	and	CCONJ
iajs-3524	272	10	therapy	therapy	NOUN
iajs-3524	272	11	2022	2022	NUM
iajs-3524	272	12	,	,	PUNCT
iajs-3524	272	13	15(1	15(1	NUM
iajs-3524	272	14	)	)	PUNCT
iajs-3524	272	15	,	,	PUNCT
iajs-3524	272	16	647	647	NUM
iajs-3524	272	17	-	-	SYM
iajs-3524	272	18	657	657	NUM
iajs-3524	272	19	.	.	PUNCT
iajs-3524	273	1	https://doi.org/10.2147/dmso.s350626	https://doi.org/10.2147/dmso.s350626	NOUN
iajs-3524	273	2	.	.	PUNCT
iajs-3524	274	1	28	28	NUM
iajs-3524	274	2	.	.	PUNCT
iajs-3524	274	3	kouskoff	kouskoff	PROPN
iajs-3524	274	4	,	,	PUNCT
iajs-3524	274	5	v.	v.	PROPN
iajs-3524	274	6	;	;	PUNCT
iajs-3524	274	7	korganow	korganow	PROPN
iajs-3524	274	8	,	,	PUNCT
iajs-3524	274	9	as	as	ADP
iajs-3524	274	10	.	.	PUNCT
iajs-3524	274	11	;	;	PUNCT
iajs-3524	274	12	duchatelle	duchatelle	PROPN
iajs-3524	274	13	,	,	PUNCT
iajs-3524	274	14	v.	v.	PROPN
iajs-3524	274	15	;	;	PUNCT
iajs-3524	274	16	degott	degott	PROPN
iajs-3524	274	17	,	,	PUNCT
iajs-3524	274	18	c.	c.	PROPN
iajs-3524	274	19	;	;	PUNCT
iajs-3524	274	20	benoist	benoist	VERB
iajs-3524	274	21	,	,	PUNCT
iajs-3524	274	22	c.	c.	PROPN
iajs-3524	274	23	;	;	PUNCT
iajs-3524	274	24	mathis	mathis	PROPN
iajs-3524	274	25	,	,	PUNCT
iajs-3524	274	26	d.	d.	PROPN
iajs-3524	274	27	organ	organ	PROPN
iajs-3524	274	28	-	-	PUNCT
iajs-3524	274	29	specific	specific	ADJ
iajs-3524	274	30	disease	disease	NOUN
iajs-3524	274	31	provoked	provoke	VERB
iajs-3524	274	32	by	by	ADP
iajs-3524	274	33	systemic	systemic	ADJ
iajs-3524	274	34	autoimmunity	autoimmunity	NOUN
iajs-3524	274	35	.	.	PUNCT
iajs-3524	275	1	cell	cell	NOUN
iajs-3524	275	2	1996	1996	NUM
iajs-3524	275	3	,	,	PUNCT
iajs-3524	275	4	87(5	87(5	NUM
iajs-3524	275	5	)	)	PUNCT
iajs-3524	275	6	,	,	PUNCT
iajs-3524	275	7	811–822	811–822	NUM
iajs-3524	275	8	.	.	PUNCT
iajs-3524	276	1	https://doi.org/10.1016/s0092-8674(00)81989-3	https://doi.org/10.1016/s0092-8674(00)81989-3	PROPN
iajs-3524	276	2	.	.	PUNCT
iajs-3524	277	1	29	29	NUM
iajs-3524	277	2	.	.	X
iajs-3524	277	3	castrogiovanni	castrogiovanni	NOUN
iajs-3524	277	4	,	,	PUNCT
iajs-3524	277	5	p.	p.	NOUN
iajs-3524	277	6	;	;	PUNCT
iajs-3524	277	7	di	di	PROPN
iajs-3524	277	8	rosa	rosa	PROPN
iajs-3524	277	9	,	,	PUNCT
iajs-3524	277	10	m.	m.	NOUN
iajs-3524	277	11	;	;	PUNCT
iajs-3524	277	12	ravalli	ravalli	PROPN
iajs-3524	277	13	,	,	PUNCT
iajs-3524	277	14	s.	s.	PROPN
iajs-3524	277	15	;	;	PUNCT
iajs-3524	277	16	castorina	castorina	PROPN
iajs-3524	277	17	,	,	PUNCT
iajs-3524	277	18	a.	a.	NOUN
iajs-3524	277	19	;	;	PUNCT
iajs-3524	277	20	guglielmino	guglielmino	PROPN
iajs-3524	277	21	,	,	PUNCT
iajs-3524	277	22	c.	c.	PROPN
iajs-3524	277	23	;	;	PUNCT
iajs-3524	277	24	imbesi	imbesi	NOUN
iajs-3524	277	25	,	,	PUNCT
iajs-3524	277	26	r.	r.	PROPN
iajs-3524	277	27	;	;	PUNCT
iajs-3524	277	28	vecchio	vecchio	PROPN
iajs-3524	277	29	,	,	PUNCT
iajs-3524	277	30	m.	m.	NOUN
iajs-3524	277	31	;	;	PUNCT
iajs-3524	277	32	drago	drago	PROPN
iajs-3524	277	33	,	,	PUNCT
iajs-3524	277	34	f.	f.	PROPN
iajs-3524	277	35	;	;	PUNCT
iajs-3524	277	36	szychlinska	szychlinska	X
iajs-3524	277	37	,	,	PUNCT
iajs-3524	277	38	m.a	m.a	PROPN
iajs-3524	277	39	.	.	PROPN
iajs-3524	277	40	;	;	PUNCT
iajs-3524	277	41	musumeci	musumeci	PROPN
iajs-3524	277	42	,	,	PUNCT
iajs-3524	277	43	g.	g.	PROPN
iajs-3524	277	44	moderate	moderate	ADJ
iajs-3524	277	45	physical	physical	ADJ
iajs-3524	277	46	activity	activity	NOUN
iajs-3524	277	47	as	as	ADP
iajs-3524	277	48	a	a	DET
iajs-3524	277	49	prevention	prevention	NOUN
iajs-3524	277	50	method	method	NOUN
iajs-3524	277	51	for	for	ADP
iajs-3524	277	52	knee	knee	NOUN
iajs-3524	277	53	osteoarthritis	osteoarthritis	NOUN
iajs-3524	277	54	and	and	CCONJ
iajs-3524	277	55	the	the	DET
iajs-3524	277	56	role	role	NOUN
iajs-3524	277	57	of	of	ADP
iajs-3524	277	58	synoviocytes	synoviocyte	NOUN
iajs-3524	277	59	as	as	ADP
iajs-3524	277	60	biological	biological	ADJ
iajs-3524	277	61	key	key	NOUN
iajs-3524	277	62	.	.	PUNCT
iajs-3524	278	1	international	international	ADJ
iajs-3524	278	2	journal	journal	NOUN
iajs-3524	278	3	of	of	ADP
iajs-3524	278	4	molecular	molecular	ADJ
iajs-3524	278	5	sciences	science	NOUN
iajs-3524	278	6	2019	2019	NUM
iajs-3524	278	7	,	,	PUNCT
iajs-3524	278	8	20(3	20(3	NOUN
iajs-3524	278	9	)	)	PUNCT
iajs-3524	278	10	,	,	PUNCT
iajs-3524	278	11	511	511	NUM
iajs-3524	278	12	.	.	PUNCT
iajs-3524	279	1	https://doi.org/10.3390/ijms20030511	https://doi.org/10.3390/ijms20030511	NOUN
iajs-3524	279	2	.	.	PUNCT
iajs-3524	280	1	30	30	NUM
iajs-3524	280	2	.	.	PUNCT
iajs-3524	281	1	hu	hu	PROPN
iajs-3524	281	2	,	,	PUNCT
iajs-3524	281	3	q.	q.	PROPN
iajs-3524	281	4	;	;	PUNCT
iajs-3524	281	5	ecker	ecker	PROPN
iajs-3524	281	6	,	,	PUNCT
iajs-3524	281	7	m.	m.	NOUN
iajs-3524	281	8	overview	overview	NOUN
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iajs-3524	281	10	mmp-13	mmp-13	NOUN
iajs-3524	281	11	as	as	ADP
iajs-3524	281	12	a	a	DET
iajs-3524	281	13	promising	promising	ADJ
iajs-3524	281	14	target	target	NOUN
iajs-3524	281	15	for	for	ADP
iajs-3524	281	16	the	the	DET
iajs-3524	281	17	treatment	treatment	NOUN
iajs-3524	281	18	of	of	ADP
iajs-3524	281	19	osteoarthritis	osteoarthritis	NOUN
iajs-3524	281	20	.	.	PUNCT
iajs-3524	282	1	international	international	ADJ
iajs-3524	282	2	journal	journal	NOUN
iajs-3524	282	3	of	of	ADP
iajs-3524	282	4	molecular	molecular	ADJ
iajs-3524	282	5	sciences	science	NOUN
iajs-3524	282	6	2021	2021	NUM
iajs-3524	282	7	,	,	PUNCT
iajs-3524	282	8	22(4	22(4	NUM
iajs-3524	282	9	)	)	PUNCT
iajs-3524	282	10	,	,	PUNCT
iajs-3524	282	11	1742	1742	NUM
iajs-3524	282	12	.	.	PUNCT
iajs-3524	283	1	https://doi.org/10.3390/ijms22041742	https://doi.org/10.3390/ijms22041742	PROPN
iajs-3524	283	2	.	.	PUNCT
iajs-3524	284	1	31	31	NUM
iajs-3524	284	2	.	.	PUNCT
iajs-3524	285	1	meehan	meehan	PROPN
iajs-3524	285	2	,	,	PUNCT
iajs-3524	285	3	r.t	r.t	PROPN
iajs-3524	285	4	.	.	PROPN
iajs-3524	285	5	;	;	PUNCT
iajs-3524	285	6	regan	regan	PROPN
iajs-3524	285	7	,	,	PUNCT
iajs-3524	285	8	e.a	e.a	PROPN
iajs-3524	285	9	.	.	PROPN
iajs-3524	285	10	;	;	PUNCT
iajs-3524	285	11	hoffman	hoffman	PROPN
iajs-3524	285	12	,	,	PUNCT
iajs-3524	285	13	e.d	e.d	PROPN
iajs-3524	285	14	.	.	PROPN
iajs-3524	285	15	;	;	PUNCT
iajs-3524	285	16	wolf	wolf	PROPN
iajs-3524	285	17	,	,	PUNCT
iajs-3524	285	18	m.l	m.l	PROPN
iajs-3524	285	19	.	.	PUNCT
iajs-3524	285	20	;	;	PUNCT
iajs-3524	285	21	gill	gill	PROPN
iajs-3524	285	22	,	,	PUNCT
iajs-3524	285	23	m.t	m.t	PROPN
iajs-3524	285	24	.	.	PROPN
iajs-3524	285	25	;	;	PUNCT
iajs-3524	285	26	crooks	crook	NOUN
iajs-3524	285	27	,	,	PUNCT
iajs-3524	285	28	j.l	j.l	PROPN
iajs-3524	285	29	.	.	PROPN
iajs-3524	285	30	;	;	PUNCT
iajs-3524	285	31	parmar	parmar	PROPN
iajs-3524	285	32	,	,	PUNCT
iajs-3524	285	33	p.j	p.j	PROPN
iajs-3524	285	34	.	.	PROPN
iajs-3524	285	35	;	;	PUNCT
iajs-3524	285	36	scheuring	scheure	VERB
iajs-3524	285	37	,	,	PUNCT
iajs-3524	285	38	r.a	r.a	PROPN
iajs-3524	285	39	.	.	PROPN
iajs-3524	285	40	;	;	PUNCT
iajs-3524	285	41	hill	hill	PROPN
iajs-3524	285	42	,	,	PUNCT
iajs-3524	285	43	j.c	j.c	PROPN
iajs-3524	285	44	.	.	PROPN
iajs-3524	285	45	;	;	PUNCT
iajs-3524	286	1	pacheco	pacheco	PROPN
iajs-3524	286	2	,	,	PUNCT
iajs-3524	286	3	k.a	k.a	PROPN
iajs-3524	286	4	.	.	PROPN
iajs-3524	286	5	;	;	PUNCT
iajs-3524	286	6	knight	knight	NOUN
iajs-3524	286	7	,	,	PUNCT
iajs-3524	286	8	v.	v.	ADP
iajs-3524	286	9	synovial	synovial	ADJ
iajs-3524	286	10	fluid	fluid	ADJ
iajs-3524	286	11	cytokines	cytokine	NOUN
iajs-3524	286	12	,	,	PUNCT
iajs-3524	286	13	chemokines	chemokine	NOUN
iajs-3524	286	14	and	and	CCONJ
iajs-3524	286	15	mmp	mmp	PROPN
iajs-3524	286	16	levels	level	NOUN
iajs-3524	286	17	in	in	ADP
iajs-3524	286	18	osteoarthritis	osteoarthritis	NOUN
iajs-3524	286	19	patients	patient	NOUN
iajs-3524	286	20	with	with	ADP
iajs-3524	286	21	knee	knee	NOUN
iajs-3524	286	22	pain	pain	NOUN
iajs-3524	286	23	display	display	VERB
iajs-3524	286	24	a	a	DET
iajs-3524	286	25	profile	profile	NOUN
iajs-3524	286	26	similar	similar	ADJ
iajs-3524	286	27	to	to	ADP
iajs-3524	286	28	many	many	ADJ
iajs-3524	286	29	rheumatoid	rheumatoid	ADJ
iajs-3524	286	30	arthritis	arthritis	NOUN
iajs-3524	286	31	patients	patient	NOUN
iajs-3524	286	32	.	.	PUNCT
iajs-3524	287	1	journal	journal	NOUN
iajs-3524	287	2	of	of	ADP
iajs-3524	287	3	clinical	clinical	ADJ
iajs-3524	287	4	medicine	medicine	NOUN
iajs-3524	287	5	2021	2021	NUM
iajs-3524	287	6	,	,	PUNCT
iajs-3524	287	7	10(21	10(21	NUM
iajs-3524	287	8	)	)	PUNCT
iajs-3524	287	9	,	,	PUNCT
iajs-3524	287	10	5027	5027	NUM
iajs-3524	287	11	.	.	PUNCT
iajs-3524	288	1	https://doi.org/10.3390/jcm10215027	https://doi.org/10.3390/jcm10215027	PROPN
iajs-3524	288	2	.	.	PUNCT
iajs-3524	289	1	32	32	NUM
iajs-3524	289	2	.	.	X
iajs-3524	290	1	chan	chan	PROPN
iajs-3524	290	2	,	,	PUNCT
iajs-3524	290	3	c.m	c.m	PROPN
iajs-3524	290	4	.	.	PROPN
iajs-3524	290	5	;	;	PUNCT
iajs-3524	290	6	macdonald	macdonald	PROPN
iajs-3524	290	7	,	,	PUNCT
iajs-3524	290	8	c.d	c.d	PROPN
iajs-3524	290	9	.	.	PROPN
iajs-3524	290	10	;	;	PUNCT
iajs-3524	290	11	litherland	litherland	PROPN
iajs-3524	290	12	,	,	PUNCT
iajs-3524	290	13	g.j	g.j	PROPN
iajs-3524	290	14	.	.	PROPN
iajs-3524	290	15	;	;	PUNCT
iajs-3524	290	16	wilkinson	wilkinson	PROPN
iajs-3524	290	17	,	,	PUNCT
iajs-3524	290	18	d.j	d.j	PROPN
iajs-3524	290	19	.	.	PROPN
iajs-3524	290	20	;	;	PUNCT
iajs-3524	290	21	skelton	skelton	PROPN
iajs-3524	290	22	,	,	PUNCT
iajs-3524	290	23	a.	a.	NOUN
iajs-3524	290	24	;	;	PUNCT
iajs-3524	290	25	europefinner	europefinner	NOUN
iajs-3524	290	26	,	,	PUNCT
iajs-3524	290	27	g.n	g.n	PROPN
iajs-3524	290	28	.	.	PROPN
iajs-3524	290	29	;	;	PUNCT
iajs-3524	290	30	rowan	rowan	PROPN
iajs-3524	290	31	,	,	PUNCT
iajs-3524	290	32	a.d	a.d	PROPN
iajs-3524	290	33	.	.	PROPN
iajs-3524	290	34	cytokine	cytokine	NOUN
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iajs-3524	290	37	mmp13	mmp13	NOUN
iajs-3524	290	38	expression	expression	NOUN
iajs-3524	290	39	in	in	ADP
iajs-3524	290	40	human	human	ADJ
iajs-3524	290	41	chondrocytes	chondrocyte	NOUN
iajs-3524	290	42	is	be	AUX
iajs-3524	290	43	dependent	dependent	ADJ
iajs-3524	290	44	on	on	ADP
iajs-3524	290	45	activating	activate	VERB
iajs-3524	290	46	transcription	transcription	NOUN
iajs-3524	290	47	factor	factor	NOUN
iajs-3524	290	48	3	3	NUM
iajs-3524	290	49	(	(	PUNCT
iajs-3524	290	50	atf3	atf3	NOUN
iajs-3524	290	51	)	)	PUNCT
iajs-3524	290	52	regulation	regulation	NOUN
iajs-3524	290	53	.	.	PUNCT
iajs-3524	291	1	journal	journal	NOUN
iajs-3524	291	2	of	of	ADP
iajs-3524	291	3	biological	biological	ADJ
iajs-3524	291	4	chemistry	chemistry	NOUN
iajs-3524	291	5	2017	2017	NUM
iajs-3524	291	6	,	,	PUNCT
iajs-3524	291	7	292(5	292(5	NUM
iajs-3524	291	8	)	)	PUNCT
iajs-3524	291	9	,	,	PUNCT
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iajs-3524	291	11	-	-	SYM
iajs-3524	291	12	1636	1636	NUM
iajs-3524	291	13	.	.	PUNCT
iajs-3524	292	1	https://doi.org/10.1074/jbc.m116.756601	https://doi.org/10.1074/jbc.m116.756601	X
iajs-3524	292	2	.	.	NOUN
iajs-3524	292	3	33	33	NUM
iajs-3524	292	4	.	.	PUNCT
iajs-3524	293	1	rowan	rowan	PROPN
iajs-3524	293	2	,	,	PUNCT
iajs-3524	293	3	a.	a.	PROPN
iajs-3524	293	4	d.	d.	PROPN
iajs-3524	293	5	;	;	PUNCT
iajs-3524	293	6	young	young	ADJ
iajs-3524	293	7	,	,	PUNCT
iajs-3524	293	8	d.	d.	PROPN
iajs-3524	293	9	a.	a.	PROPN
iajs-3524	293	10	;	;	PUNCT
iajs-3524	293	11	collagenase	collagenase	NOUN
iajs-3524	293	12	gene	gene	NOUN
iajs-3524	293	13	regulation	regulation	NOUN
iajs-3524	293	14	by	by	ADP
iajs-3524	293	15	pro	pro	ADJ
iajs-3524	293	16	-	-	ADJ
iajs-3524	293	17	inflammatory	inflammatory	ADJ
iajs-3524	293	18	cytokines	cytokine	NOUN
iajs-3524	293	19	in	in	ADP
iajs-3524	293	20	cartilage	cartilage	NOUN
iajs-3524	293	21	.	.	PUNCT
iajs-3524	294	1	frontiers	frontier	NOUN
iajs-3524	294	2	in	in	ADP
iajs-3524	294	3	bioscience	bioscience	NOUN
iajs-3524	294	4	-	-	PUNCT
iajs-3524	294	5	landmark	landmark	NOUN
iajs-3524	294	6	2007	2007	NUM
iajs-3524	294	7	,	,	PUNCT
iajs-3524	294	8	12(1	12(1	NUM
iajs-3524	294	9	)	)	PUNCT
iajs-3524	294	10	,	,	PUNCT
iajs-3524	294	11	536	536	NUM
iajs-3524	294	12	-	-	SYM
iajs-3524	294	13	550	550	NUM
iajs-3524	294	14	.	.	PUNCT
iajs-3524	295	1	https://doi.org/10.2741/2080	https://doi.org/10.2741/2080	NOUN
iajs-3524	295	2	.	.	PUNCT
iajs-3524	296	1	34	34	NUM
iajs-3524	296	2	.	.	X
iajs-3524	296	3	catterall	catterall	PROPN
iajs-3524	296	4	,	,	PUNCT
iajs-3524	296	5	j.b	j.b	PROPN
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iajs-3524	296	7	;	;	PUNCT
iajs-3524	296	8	carrere	carrere	PROPN
iajs-3524	296	9	,	,	PUNCT
iajs-3524	296	10	s.	s.	PROPN
iajs-3524	296	11	;	;	PUNCT
iajs-3524	296	12	koshy	koshy	ADJ
iajs-3524	296	13	,	,	PUNCT
iajs-3524	296	14	p.j.t	p.j.t	NOUN
iajs-3524	296	15	.	.	PUNCT
iajs-3524	296	16	;	;	PUNCT
iajs-3524	296	17	degnan	degnan	PROPN
iajs-3524	296	18	,	,	PUNCT
iajs-3524	296	19	b.a	b.a	PROPN
iajs-3524	296	20	.	.	PROPN
iajs-3524	296	21	;	;	PUNCT
iajs-3524	296	22	shingleton	shingleton	PROPN
iajs-3524	296	23	,	,	PUNCT
iajs-3524	296	24	w.d	w.d	PROPN
iajs-3524	296	25	.	.	PROPN
iajs-3524	296	26	;	;	PUNCT
iajs-3524	296	27	brinckerhoff	brinckerhoff	PROPN
iajs-3524	296	28	,	,	PUNCT
iajs-3524	296	29	c.e	c.e	PROPN
iajs-3524	296	30	.	.	PROPN
iajs-3524	296	31	;	;	PUNCT
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iajs-3524	296	33	,	,	PUNCT
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iajs-3524	296	35	.	.	PROPN
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iajs-3524	296	37	induction	induction	NOUN
iajs-3524	296	38	of	of	ADP
iajs-3524	296	39	matrix	matrix	NOUN
iajs-3524	296	40	metalloproteinase	metalloproteinase	NOUN
iajs-3524	296	41	1	1	NUM
iajs-3524	296	42	by	by	ADP
iajs-3524	296	43	interleukin‐1α	interleukin‐1α	NOUN
iajs-3524	296	44	and	and	CCONJ
iajs-3524	296	45	oncostatin	oncostatin	NOUN
iajs-3524	296	46	m	m	NOUN
iajs-3524	296	47	in	in	ADP
iajs-3524	296	48	human	human	ADJ
iajs-3524	296	49	chondrocytes	chondrocyte	NOUN
iajs-3524	296	50	involves	involve	VERB
iajs-3524	296	51	signal	signal	ADJ
iajs-3524	296	52	transducer	transducer	NOUN
iajs-3524	296	53	and	and	CCONJ
iajs-3524	296	54	activator	activator	NOUN
iajs-3524	296	55	of	of	ADP
iajs-3524	296	56	transcription	transcription	NOUN
iajs-3524	296	57	and	and	CCONJ
iajs-3524	296	58	activator	activator	NOUN
iajs-3524	296	59	protein	protein	NOUN
iajs-3524	296	60	1	1	NUM
iajs-3524	296	61	transcription	transcription	NOUN
iajs-3524	296	62	factors	factor	NOUN
iajs-3524	296	63	via	via	ADP
iajs-3524	296	64	a	a	DET
iajs-3524	296	65	novel	novel	ADJ
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iajs-3524	296	67	.	.	PUNCT
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iajs-3524	297	2	and	and	CCONJ
iajs-3524	297	3	rheumatism	rheumatism	NOUN
iajs-3524	297	4	2001	2001	NUM
iajs-3524	297	5	,	,	PUNCT
iajs-3524	297	6	44(10	44(10	NUM
iajs-3524	297	7	)	)	PUNCT
iajs-3524	297	8	,	,	PUNCT
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iajs-3524	297	10	-	-	SYM
iajs-3524	297	11	2310	2310	NUM
iajs-3524	297	12	.	.	PUNCT
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iajs-3524	298	2	.	.	PROPN
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iajs-3524	299	2	.	.	PUNCT
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iajs-3524	300	2	,	,	PUNCT
iajs-3524	300	3	g.j	g.j	PROPN
iajs-3524	300	4	.	.	PROPN
iajs-3524	300	5	;	;	PUNCT
iajs-3524	300	6	elias	elias	PROPN
iajs-3524	300	7	,	,	PUNCT
iajs-3524	300	8	m.s	m.s	PROPN
iajs-3524	300	9	.	.	PROPN
iajs-3524	300	10	;	;	PUNCT
iajs-3524	301	1	hui	hui	PROPN
iajs-3524	301	2	,	,	PUNCT
iajs-3524	301	3	w.	w.	PROPN
iajs-3524	301	4	;	;	PUNCT
iajs-3524	301	5	macdonald	macdonald	PROPN
iajs-3524	301	6	,	,	PUNCT
iajs-3524	301	7	c.d	c.d	PROPN
iajs-3524	301	8	.	.	PROPN
iajs-3524	301	9	;	;	PUNCT
iajs-3524	301	10	catterall	catterall	PROPN
iajs-3524	301	11	,	,	PUNCT
iajs-3524	301	12	j.b	j.b	PROPN
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iajs-3524	301	14	;	;	PUNCT
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iajs-3524	301	38	stat3	stat3	PROPN
iajs-3524	301	39	-	-	PUNCT
iajs-3524	301	40	and	and	CCONJ
iajs-3524	301	41	erk	erk	NOUN
iajs-3524	301	42	-	-	PUNCT
iajs-3524	301	43	dependent	dependent	ADJ
iajs-3524	301	44	c	c	NOUN
iajs-3524	301	45	-	-	PUNCT
iajs-3524	301	46	fos	fos	NOUN
iajs-3524	301	47	induction	induction	NOUN
iajs-3524	301	48	.	.	PUNCT
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iajs-3524	302	2	of	of	ADP
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iajs-3524	302	5	2010	2010	NUM
iajs-3524	302	6	,	,	PUNCT
iajs-3524	302	7	285(29	285(29	NUM
iajs-3524	302	8	)	)	PUNCT
iajs-3524	302	9	,	,	PUNCT
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iajs-3524	302	11	-	-	SYM
iajs-3524	302	12	22425	22425	NUM
iajs-3524	302	13	.	.	PUNCT
iajs-3524	303	1	https://doi.org/10.1074/jbc.m110.120121%20	https://doi.org/10.1074/jbc.m110.120121%20	PROPN
iajs-3524	303	2	.	.	PUNCT
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iajs-3524	304	4	https://doi.org/10.1016/0014-5793(95)01539-6	https://doi.org/10.1016/0014-5793(95)01539-6	ADJ
iajs-3524	304	5	https://doi.org/10.2174/092986711794940905	https://doi.org/10.2174/092986711794940905	VERB
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iajs-3524	304	11	https://doi.org/10.1074/jbc.m116.756601	https://doi.org/10.1074/jbc.m116.756601	PROPN
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iajs-3524	304	13	.	.	PUNCT
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iajs-3524	305	2	https://doi.org/10.1074/jbc.m110.120121	https://doi.org/10.1074/jbc.m110.120121	NUM
iajs-3524	305	3	ihjpas	ihjpa	NOUN
iajs-3524	305	4	.	.	PUNCT
iajs-3524	306	1	2024	2024	NUM
iajs-3524	306	2	,	,	PUNCT
iajs-3524	306	3	37(4	37(4	NOUN
iajs-3524	306	4	)	)	PUNCT
iajs-3524	306	5	296	296	NUM
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iajs-3524	306	7	.	.	PUNCT
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iajs-3524	307	3	g.j	g.j	PROPN
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iajs-3524	307	5	;	;	PUNCT
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iajs-3524	307	7	,	,	PUNCT
iajs-3524	307	8	c.	c.	PROPN
iajs-3524	307	9	;	;	PUNCT
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iajs-3524	307	11	,	,	PUNCT
iajs-3524	307	12	r.l	r.l	PROPN
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iajs-3524	307	14	;	;	PUNCT
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iajs-3524	307	20	,	,	PUNCT
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iajs-3524	307	37	collagenolysis	collagenolysis	NOUN
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iajs-3524	307	39	phosphatidylinositol	phosphatidylinositol	NOUN
iajs-3524	307	40	3	3	NUM
iajs-3524	307	41	-	-	PUNCT
iajs-3524	307	42	kinase/	kinase/	NOUN
iajs-3524	307	43	aktsignaling	aktsignaling	NOUN
iajs-3524	307	44	-	-	PUNCT
iajs-3524	307	45	dependent	dependent	ADJ
iajs-3524	307	46	.	.	PUNCT
iajs-3524	308	1	journal	journal	NOUN
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iajs-3524	308	8	)	)	PUNCT
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iajs-3524	308	13	.	.	PUNCT
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iajs-3524	309	2	.	.	PUNCT
iajs-3524	310	1	https://doi.org/10.1074/jbc.m710136200	https://doi.org/10.1074/jbc.m710136200	X