id	sid	tid	token	lemma	pos
iajs-4030	1	1	274	274	NUM
iajs-4030	1	2	©	©	PROPN
iajs-4030	1	3	2025the	2025the	NUM
iajs-4030	1	4	author(s	author(s	NOUN
iajs-4030	1	5	)	)	PUNCT
iajs-4030	1	6	.	.	PUNCT
iajs-4030	2	1	published	publish	VERB
iajs-4030	2	2	by	by	ADP
iajs-4030	2	3	college	college	NOUN
iajs-4030	2	4	of	of	ADP
iajs-4030	2	5	education	education	NOUN
iajs-4030	2	6	for	for	ADP
iajs-4030	2	7	pure	pure	ADJ
iajs-4030	2	8	science	science	NOUN
iajs-4030	2	9	(	(	PUNCT
iajs-4030	2	10	ibn	ibn	PROPN
iajs-4030	2	11	al	al	PROPN
iajs-4030	2	12	-	-	PUNCT
iajs-4030	2	13	haitham	haitham	PROPN
iajs-4030	2	14	)	)	PUNCT
iajs-4030	2	15	,	,	PUNCT
iajs-4030	2	16	university	university	NOUN
iajs-4030	2	17	of	of	ADP
iajs-4030	2	18	baghdad	baghdad	PROPN
iajs-4030	2	19	.	.	PUNCT
iajs-4030	3	1	this	this	PRON
iajs-4030	3	2	is	be	AUX
iajs-4030	3	3	an	an	DET
iajs-4030	3	4	open	open	ADJ
iajs-4030	3	5	-	-	PUNCT
iajs-4030	3	6	access	access	NOUN
iajs-4030	3	7	article	article	NOUN
iajs-4030	3	8	distributed	distribute	VERB
iajs-4030	3	9	under	under	ADP
iajs-4030	3	10	the	the	DET
iajs-4030	3	11	terms	term	NOUN
iajs-4030	3	12	of	of	ADP
iajs-4030	3	13	the	the	DET
iajs-4030	3	14	creative	creative	ADJ
iajs-4030	3	15	commons	common	NOUN
iajs-4030	3	16	attribution	attribution	NOUN
iajs-4030	3	17	4.0	4.0	NUM
iajs-4030	3	18	international	international	ADJ
iajs-4030	3	19	license	license	NOUN
iajs-4030	3	20	emerging	emerge	VERB
iajs-4030	3	21	role	role	NOUN
iajs-4030	3	22	of	of	ADP
iajs-4030	3	23	microtubule	microtubule	NOUN
iajs-4030	3	24	-	-	PUNCT
iajs-4030	3	25	associated	associate	VERB
iajs-4030	3	26	protein	protein	NOUN
iajs-4030	3	27	2	2	NUM
iajs-4030	3	28	as	as	ADP
iajs-4030	3	29	a	a	DET
iajs-4030	3	30	prognostic	prognostic	ADJ
iajs-4030	3	31	factor	factor	NOUN
iajs-4030	3	32	for	for	ADP
iajs-4030	3	33	renal	renal	ADJ
iajs-4030	3	34	dysfunction	dysfunction	NOUN
iajs-4030	3	35	fatima	fatima	PROPN
iajs-4030	3	36	ghazi	ghazi	PROPN
iajs-4030	3	37	talab	talab	PROPN
iajs-4030	3	38	1,2	1,2	NUM
iajs-4030	3	39	and	and	CCONJ
iajs-4030	3	40	hind	hind	NOUN
iajs-4030	3	41	shakir	shakir	PROPN
iajs-4030	3	42	ahmed	ahmed	PROPN
iajs-4030	3	43	2	2	NUM
iajs-4030	3	44	*	*	SYM
iajs-4030	3	45	1	1	NUM
iajs-4030	3	46	college	college	NOUN
iajs-4030	3	47	of	of	ADP
iajs-4030	3	48	medicine	medicine	NOUN
iajs-4030	3	49	,	,	PUNCT
iajs-4030	3	50	al	al	PROPN
iajs-4030	3	51	nahrain	nahrain	PROPN
iajs-4030	3	52	university	university	PROPN
iajs-4030	3	53	,	,	PUNCT
iajs-4030	3	54	baghdad	baghdad	PROPN
iajs-4030	3	55	,	,	PUNCT
iajs-4030	3	56	iraq	iraq	PROPN
iajs-4030	3	57	.	.	PUNCT
iajs-4030	4	1	2	2	NUM
iajs-4030	4	2	department	department	NOUN
iajs-4030	4	3	of	of	ADP
iajs-4030	4	4	chemistry	chemistry	NOUN
iajs-4030	4	5	,	,	PUNCT
iajs-4030	4	6	college	college	NOUN
iajs-4030	4	7	of	of	ADP
iajs-4030	4	8	education	education	NOUN
iajs-4030	4	9	for	for	ADP
iajs-4030	4	10	pure	pure	ADJ
iajs-4030	4	11	science	science	NOUN
iajs-4030	4	12	(	(	PUNCT
iajs-4030	4	13	ibn	ibn	PROPN
iajs-4030	4	14	al	al	PROPN
iajs-4030	4	15	-	-	PUNCT
iajs-4030	4	16	haitham	haitham	PROPN
iajs-4030	4	17	)	)	PUNCT
iajs-4030	4	18	,	,	PUNCT
iajs-4030	4	19	university	university	NOUN
iajs-4030	4	20	of	of	ADP
iajs-4030	4	21	baghdad	baghdad	PROPN
iajs-4030	4	22	,	,	PUNCT
iajs-4030	4	23	baghdad	baghdad	PROPN
iajs-4030	4	24	,	,	PUNCT
iajs-4030	4	25	iraq	iraq	PROPN
iajs-4030	4	26	.	.	PUNCT
iajs-4030	5	1	*	*	PUNCT
iajs-4030	5	2	corresponding	correspond	VERB
iajs-4030	5	3	author	author	NOUN
iajs-4030	5	4	.	.	PUNCT
iajs-4030	6	1	received	receive	VERB
iajs-4030	6	2	:	:	PUNCT
iajs-4030	6	3	28	28	NUM
iajs-4030	6	4	june	june	PROPN
iajs-4030	6	5	2024	2024	NUM
iajs-4030	6	6	accepted	accept	VERB
iajs-4030	6	7	:	:	PUNCT
iajs-4030	6	8	18	18	NUM
iajs-4030	6	9	november	november	PROPN
iajs-4030	6	10	2024	2024	NUM
iajs-4030	6	11	published	publish	VERB
iajs-4030	6	12	:	:	PUNCT
iajs-4030	6	13	20	20	NUM
iajs-4030	6	14	july	july	NOUN
iajs-4030	6	15	2025	2025	NUM
iajs-4030	6	16	doi.org/10.30526/38.3.4030	doi.org/10.30526/38.3.4030	NOUN
iajs-4030	6	17	abstract	abstract	ADJ
iajs-4030	6	18	chronic	chronic	ADJ
iajs-4030	6	19	kidney	kidney	NOUN
iajs-4030	6	20	disease	disease	NOUN
iajs-4030	6	21	(	(	PUNCT
iajs-4030	6	22	ckd	ckd	NOUN
iajs-4030	6	23	)	)	PUNCT
iajs-4030	6	24	is	be	AUX
iajs-4030	6	25	a	a	DET
iajs-4030	6	26	severe	severe	ADJ
iajs-4030	6	27	medical	medical	ADJ
iajs-4030	6	28	disorder	disorder	NOUN
iajs-4030	6	29	manifested	manifest	VERB
iajs-4030	6	30	by	by	ADP
iajs-4030	6	31	a	a	DET
iajs-4030	6	32	decline	decline	NOUN
iajs-4030	6	33	in	in	ADP
iajs-4030	6	34	kidney	kidney	NOUN
iajs-4030	6	35	function	function	NOUN
iajs-4030	6	36	over	over	ADP
iajs-4030	6	37	an	an	DET
iajs-4030	6	38	extended	extended	ADJ
iajs-4030	6	39	period	period	NOUN
iajs-4030	6	40	.	.	PUNCT
iajs-4030	7	1	this	this	PRON
iajs-4030	7	2	leads	lead	VERB
iajs-4030	7	3	to	to	ADP
iajs-4030	7	4	the	the	DET
iajs-4030	7	5	accumulation	accumulation	NOUN
iajs-4030	7	6	of	of	ADP
iajs-4030	7	7	toxins	toxin	NOUN
iajs-4030	7	8	and	and	CCONJ
iajs-4030	7	9	the	the	DET
iajs-4030	7	10	gradual	gradual	ADJ
iajs-4030	7	11	inability	inability	NOUN
iajs-4030	7	12	to	to	PART
iajs-4030	7	13	remove	remove	VERB
iajs-4030	7	14	excess	excess	ADJ
iajs-4030	7	15	waste	waste	NOUN
iajs-4030	7	16	and	and	CCONJ
iajs-4030	7	17	fluids	fluid	NOUN
iajs-4030	7	18	from	from	ADP
iajs-4030	7	19	the	the	DET
iajs-4030	7	20	body	body	NOUN
iajs-4030	7	21	.	.	PUNCT
iajs-4030	8	1	microtubule	microtubule	NOUN
iajs-4030	8	2	-	-	PUNCT
iajs-4030	8	3	associated	associate	VERB
iajs-4030	8	4	protein	protein	NOUN
iajs-4030	8	5	2	2	NUM
iajs-4030	8	6	(	(	PUNCT
iajs-4030	8	7	map2	map2	PROPN
iajs-4030	8	8	)	)	PUNCT
iajs-4030	8	9	is	be	AUX
iajs-4030	8	10	part	part	NOUN
iajs-4030	8	11	of	of	ADP
iajs-4030	8	12	a	a	DET
iajs-4030	8	13	protein	protein	NOUN
iajs-4030	8	14	family	family	NOUN
iajs-4030	8	15	that	that	PRON
iajs-4030	8	16	regulates	regulate	VERB
iajs-4030	8	17	microtubule	microtubule	NOUN
iajs-4030	8	18	structure	structure	NOUN
iajs-4030	8	19	and	and	CCONJ
iajs-4030	8	20	cellular	cellular	ADJ
iajs-4030	8	21	metabolism	metabolism	NOUN
iajs-4030	8	22	.	.	PUNCT
iajs-4030	9	1	this	this	DET
iajs-4030	9	2	study	study	NOUN
iajs-4030	9	3	aims	aim	VERB
iajs-4030	9	4	to	to	PART
iajs-4030	9	5	analyze	analyze	VERB
iajs-4030	9	6	the	the	DET
iajs-4030	9	7	effectiveness	effectiveness	NOUN
iajs-4030	9	8	of	of	ADP
iajs-4030	9	9	these	these	DET
iajs-4030	9	10	parameters	parameter	NOUN
iajs-4030	9	11	in	in	ADP
iajs-4030	9	12	evaluating	evaluate	VERB
iajs-4030	9	13	ckd	ckd	PROPN
iajs-4030	9	14	and	and	CCONJ
iajs-4030	9	15	its	its	PRON
iajs-4030	9	16	associated	associate	VERB
iajs-4030	9	17	mechanisms	mechanism	NOUN
iajs-4030	9	18	in	in	ADP
iajs-4030	9	19	iraqi	iraqi	ADJ
iajs-4030	9	20	patients	patient	NOUN
iajs-4030	9	21	.	.	PUNCT
iajs-4030	10	1	the	the	DET
iajs-4030	10	2	study	study	NOUN
iajs-4030	10	3	was	be	AUX
iajs-4030	10	4	conducted	conduct	VERB
iajs-4030	10	5	from	from	ADP
iajs-4030	10	6	december	december	PROPN
iajs-4030	10	7	2023	2023	NUM
iajs-4030	10	8	to	to	PART
iajs-4030	10	9	may	may	PROPN
iajs-4030	10	10	2024	2024	NUM
iajs-4030	10	11	.	.	PUNCT
iajs-4030	11	1	ninety	ninety	NUM
iajs-4030	11	2	subjects	subject	NOUN
iajs-4030	11	3	enrolled	enrol	VERB
iajs-4030	11	4	in	in	ADP
iajs-4030	11	5	this	this	DET
iajs-4030	11	6	study	study	NOUN
iajs-4030	11	7	:	:	PUNCT
iajs-4030	11	8	60	60	NUM
iajs-4030	11	9	patients	patient	NOUN
iajs-4030	11	10	with	with	ADP
iajs-4030	11	11	ckd	ckd	PROPN
iajs-4030	11	12	who	who	PRON
iajs-4030	11	13	attended	attend	VERB
iajs-4030	11	14	the	the	DET
iajs-4030	11	15	baghdad	baghdad	PROPN
iajs-4030	11	16	teaching	teach	VERB
iajs-4030	11	17	hospital	hospital	NOUN
iajs-4030	11	18	/	/	SYM
iajs-4030	11	19	medical	medical	ADJ
iajs-4030	11	20	city/	city/	NUM
iajs-4030	11	21	dialysis	dialysis	NOUN
iajs-4030	11	22	unit	unit	NOUN
iajs-4030	11	23	in	in	ADP
iajs-4030	11	24	baghdad	baghdad	PROPN
iajs-4030	11	25	,	,	PUNCT
iajs-4030	11	26	iraq	iraq	PROPN
iajs-4030	11	27	.	.	PUNCT
iajs-4030	12	1	additionally	additionally	ADV
iajs-4030	12	2	,	,	PUNCT
iajs-4030	12	3	30	30	NUM
iajs-4030	12	4	healthy	healthy	ADJ
iajs-4030	12	5	subjects	subject	NOUN
iajs-4030	12	6	were	be	AUX
iajs-4030	12	7	designated	designate	VERB
iajs-4030	12	8	as	as	ADP
iajs-4030	12	9	the	the	DET
iajs-4030	12	10	control	control	NOUN
iajs-4030	12	11	group	group	NOUN
iajs-4030	12	12	.	.	PUNCT
iajs-4030	13	1	their	their	PRON
iajs-4030	13	2	ages	age	NOUN
iajs-4030	13	3	ranged	range	VERB
iajs-4030	13	4	from	from	ADP
iajs-4030	13	5	48	48	NUM
iajs-4030	13	6	to	to	PART
iajs-4030	13	7	65	65	NUM
iajs-4030	13	8	years	year	NOUN
iajs-4030	13	9	.	.	PUNCT
iajs-4030	14	1	the	the	DET
iajs-4030	14	2	present	present	ADJ
iajs-4030	14	3	results	result	NOUN
iajs-4030	14	4	indicated	indicate	VERB
iajs-4030	14	5	significantly	significantly	ADV
iajs-4030	14	6	higher	high	ADJ
iajs-4030	14	7	serum	serum	NOUN
iajs-4030	14	8	map2	map2	NOUN
iajs-4030	14	9	levels	level	NOUN
iajs-4030	14	10	in	in	ADP
iajs-4030	14	11	ckd	ckd	PROPN
iajs-4030	14	12	patients	patient	NOUN
iajs-4030	14	13	undergoing	undergo	VERB
iajs-4030	14	14	dialysis	dialysis	NOUN
iajs-4030	14	15	as	as	ADP
iajs-4030	14	16	compared	compare	VERB
iajs-4030	14	17	to	to	ADP
iajs-4030	14	18	the	the	DET
iajs-4030	14	19	control	control	NOUN
iajs-4030	14	20	(	(	PUNCT
iajs-4030	14	21	616.10±12.25	616.10±12.25	NOUN
iajs-4030	14	22	vs.	vs.	X
iajs-4030	14	23	125.48±10.14	125.48±10.14	NUM
iajs-4030	14	24	)	)	PUNCT
iajs-4030	14	25	ρg	ρg	NOUN
iajs-4030	14	26	/	/	SYM
iajs-4030	14	27	ml	ml	NOUN
iajs-4030	14	28	.	.	PUNCT
iajs-4030	15	1	in	in	ADP
iajs-4030	15	2	addition	addition	NOUN
iajs-4030	15	3	,	,	PUNCT
iajs-4030	15	4	the	the	DET
iajs-4030	15	5	present	present	ADJ
iajs-4030	15	6	results	result	NOUN
iajs-4030	15	7	revealed	reveal	VERB
iajs-4030	15	8	a	a	DET
iajs-4030	15	9	significant	significant	ADJ
iajs-4030	15	10	positive	positive	ADJ
iajs-4030	15	11	correlation	correlation	NOUN
iajs-4030	15	12	between	between	ADP
iajs-4030	15	13	serum	serum	NOUN
iajs-4030	15	14	map2	map2	PROPN
iajs-4030	15	15	and	and	CCONJ
iajs-4030	15	16	levels	level	NOUN
iajs-4030	15	17	of	of	ADP
iajs-4030	15	18	various	various	ADJ
iajs-4030	15	19	parameters	parameter	NOUN
iajs-4030	15	20	,	,	PUNCT
iajs-4030	15	21	including	include	VERB
iajs-4030	15	22	fasting	fast	VERB
iajs-4030	15	23	glucose	glucose	NOUN
iajs-4030	15	24	,	,	PUNCT
iajs-4030	15	25	lipid	lipid	NOUN
iajs-4030	15	26	profile	profile	NOUN
iajs-4030	15	27	,	,	PUNCT
iajs-4030	15	28	and	and	CCONJ
iajs-4030	15	29	renal	renal	ADJ
iajs-4030	15	30	function	function	NOUN
iajs-4030	15	31	tests	test	NOUN
iajs-4030	15	32	.	.	PUNCT
iajs-4030	16	1	a	a	DET
iajs-4030	16	2	significant	significant	ADJ
iajs-4030	16	3	negative	negative	ADJ
iajs-4030	16	4	correlation	correlation	NOUN
iajs-4030	16	5	exists	exist	VERB
iajs-4030	16	6	between	between	ADP
iajs-4030	16	7	serum	serum	NOUN
iajs-4030	16	8	map2	map2	NOUN
iajs-4030	16	9	levels	level	NOUN
iajs-4030	16	10	and	and	CCONJ
iajs-4030	16	11	serum	serum	NOUN
iajs-4030	16	12	total	total	ADJ
iajs-4030	16	13	protein	protein	NOUN
iajs-4030	16	14	,	,	PUNCT
iajs-4030	16	15	albumin	albumin	NOUN
iajs-4030	16	16	,	,	PUNCT
iajs-4030	16	17	and	and	CCONJ
iajs-4030	16	18	estimated	estimate	VERB
iajs-4030	16	19	glomerular	glomerular	ADJ
iajs-4030	16	20	filtration	filtration	NOUN
iajs-4030	16	21	rate	rate	NOUN
iajs-4030	16	22	.	.	PUNCT
iajs-4030	17	1	it	it	PRON
iajs-4030	17	2	was	be	AUX
iajs-4030	17	3	found	find	VERB
iajs-4030	17	4	that	that	SCONJ
iajs-4030	17	5	higher	high	ADJ
iajs-4030	17	6	levels	level	NOUN
iajs-4030	17	7	of	of	ADP
iajs-4030	17	8	serum	serum	NOUN
iajs-4030	17	9	map2	map2	PROPN
iajs-4030	17	10	in	in	ADP
iajs-4030	17	11	hemodialysis	hemodialysis	NOUN
iajs-4030	17	12	patients	patient	NOUN
iajs-4030	17	13	reveal	reveal	VERB
iajs-4030	17	14	their	their	PRON
iajs-4030	17	15	critical	critical	ADJ
iajs-4030	17	16	role	role	NOUN
iajs-4030	17	17	in	in	ADP
iajs-4030	17	18	renal	renal	ADJ
iajs-4030	17	19	dysfunction	dysfunction	NOUN
iajs-4030	17	20	.	.	PUNCT
iajs-4030	18	1	therefore	therefore	ADV
iajs-4030	18	2	,	,	PUNCT
iajs-4030	18	3	this	this	DET
iajs-4030	18	4	factor	factor	NOUN
iajs-4030	18	5	may	may	AUX
iajs-4030	18	6	serve	serve	VERB
iajs-4030	18	7	as	as	ADP
iajs-4030	18	8	a	a	DET
iajs-4030	18	9	biomarker	biomarker	NOUN
iajs-4030	18	10	of	of	ADP
iajs-4030	18	11	kidney	kidney	NOUN
iajs-4030	18	12	injury	injury	NOUN
iajs-4030	18	13	progression	progression	NOUN
iajs-4030	18	14	among	among	ADP
iajs-4030	18	15	patients	patient	NOUN
iajs-4030	18	16	with	with	ADP
iajs-4030	18	17	ckd	ckd	PROPN
iajs-4030	18	18	.	.	PUNCT
iajs-4030	19	1	keywords	keyword	NOUN
iajs-4030	19	2	:	:	PUNCT
iajs-4030	19	3	chronic	chronic	ADJ
iajs-4030	19	4	kidney	kidney	NOUN
iajs-4030	19	5	disease	disease	NOUN
iajs-4030	19	6	,	,	PUNCT
iajs-4030	19	7	glomerular	glomerular	ADJ
iajs-4030	19	8	filtration	filtration	NOUN
iajs-4030	19	9	rate	rate	NOUN
iajs-4030	19	10	,	,	PUNCT
iajs-4030	19	11	lipid	lipid	NOUN
iajs-4030	19	12	profilr	profilr	PROPN
iajs-4030	19	13	,	,	PUNCT
iajs-4030	19	14	microtubule	microtubule	NOUN
iajs-4030	19	15	associated	associate	VERB
iajs-4030	19	16	protein	protein	NOUN
iajs-4030	19	17	2	2	NUM
iajs-4030	19	18	,	,	PUNCT
iajs-4030	19	19	renal	renal	ADJ
iajs-4030	19	20	function	function	NOUN
iajs-4030	19	21	test	test	NOUN
iajs-4030	19	22	.	.	PUNCT
iajs-4030	20	1	1	1	X
iajs-4030	20	2	.	.	X
iajs-4030	20	3	introduction	introduction	NOUN
iajs-4030	20	4	chronic	chronic	ADJ
iajs-4030	20	5	kidney	kidney	NOUN
iajs-4030	20	6	disease	disease	NOUN
iajs-4030	20	7	(	(	PUNCT
iajs-4030	20	8	ckd	ckd	NOUN
iajs-4030	20	9	)	)	PUNCT
iajs-4030	20	10	is	be	AUX
iajs-4030	20	11	characterized	characterize	VERB
iajs-4030	20	12	by	by	ADP
iajs-4030	20	13	a	a	DET
iajs-4030	20	14	progressive	progressive	ADJ
iajs-4030	20	15	decline	decline	NOUN
iajs-4030	20	16	in	in	ADP
iajs-4030	20	17	renal	renal	ADJ
iajs-4030	20	18	function	function	NOUN
iajs-4030	20	19	over	over	ADP
iajs-4030	20	20	time	time	NOUN
iajs-4030	20	21	,	,	PUNCT
iajs-4030	20	22	typically	typically	ADV
iajs-4030	20	23	resulting	result	VERB
iajs-4030	20	24	from	from	ADP
iajs-4030	20	25	a	a	DET
iajs-4030	20	26	reduction	reduction	NOUN
iajs-4030	20	27	in	in	ADP
iajs-4030	20	28	blood	blood	NOUN
iajs-4030	20	29	supply	supply	NOUN
iajs-4030	20	30	to	to	ADP
iajs-4030	20	31	the	the	DET
iajs-4030	20	32	kidneys	kidney	NOUN
iajs-4030	20	33	.	.	PUNCT
iajs-4030	21	1	this	this	DET
iajs-4030	21	2	disorder	disorder	NOUN
iajs-4030	21	3	results	result	VERB
iajs-4030	21	4	in	in	ADP
iajs-4030	21	5	cellular	cellular	ADJ
iajs-4030	21	6	structural	structural	ADJ
iajs-4030	21	7	anomalies	anomaly	NOUN
iajs-4030	21	8	,	,	PUNCT
iajs-4030	21	9	including	include	VERB
iajs-4030	21	10	those	those	PRON
iajs-4030	21	11	inside	inside	ADP
iajs-4030	21	12	neural	neural	ADJ
iajs-4030	21	13	cells	cell	NOUN
iajs-4030	21	14	(	(	PUNCT
iajs-4030	21	15	1	1	NUM
iajs-4030	21	16	)	)	PUNCT
iajs-4030	21	17	.	.	PUNCT
iajs-4030	22	1	waste	waste	NOUN
iajs-4030	22	2	and	and	CCONJ
iajs-4030	22	3	toxins	toxin	NOUN
iajs-4030	22	4	build	build	VERB
iajs-4030	22	5	up	up	ADP
iajs-4030	22	6	in	in	ADP
iajs-4030	22	7	the	the	DET
iajs-4030	22	8	blood	blood	NOUN
iajs-4030	22	9	of	of	ADP
iajs-4030	22	10	patients	patient	NOUN
iajs-4030	22	11	with	with	ADP
iajs-4030	22	12	ckd	ckd	PROPN
iajs-4030	22	13	,	,	PUNCT
iajs-4030	22	14	which	which	PRON
iajs-4030	22	15	negatively	negatively	ADV
iajs-4030	22	16	impacts	impact	VERB
iajs-4030	22	17	general	general	ADJ
iajs-4030	22	18	health	health	NOUN
iajs-4030	22	19	and	and	CCONJ
iajs-4030	22	20	raises	raise	VERB
iajs-4030	22	21	the	the	DET
iajs-4030	22	22	risk	risk	NOUN
iajs-4030	22	23	of	of	ADP
iajs-4030	22	24	cardiovascular	cardiovascular	ADJ
iajs-4030	22	25	diseases	disease	NOUN
iajs-4030	22	26	(	(	PUNCT
iajs-4030	22	27	cvd	cvd	NOUN
iajs-4030	22	28	)	)	PUNCT
iajs-4030	22	29	.	.	PUNCT
iajs-4030	23	1	because	because	SCONJ
iajs-4030	23	2	the	the	DET
iajs-4030	23	3	kidneys	kidney	NOUN
iajs-4030	23	4	play	play	VERB
iajs-4030	23	5	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	NOUN
iajs-4030	23	6	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	ADJ
iajs-4030	23	7	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	8	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	9	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	PROPN
iajs-4030	23	10	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	PROPN
iajs-4030	23	11	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	12	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	13	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	PROPN
iajs-4030	23	14	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	PROPN
iajs-4030	23	15	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	16	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	17	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	PROPN
iajs-4030	23	18	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	PROPN
iajs-4030	23	19	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	20	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	21	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	PROPN
iajs-4030	23	22	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	PROPN
iajs-4030	23	23	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	24	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	25	https://orcid.org/0009-0008-9637-1418	https://orcid.org/0009-0008-9637-1418	PROPN
iajs-4030	23	26	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	mailto:fatima.ghazi2205p@ihcoedu.uobaghdad.edu.iq	PROPN
iajs-4030	23	27	https://orcid.org/0000-0001-6846-1549	https://orcid.org/0000-0001-6846-1549	PROPN
iajs-4030	23	28	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	mailto:hind.sh.a@ihcoedu.uobaghdad.edu.iq	NOUN
iajs-4030	23	29	ihjpas	ihjpa	NOUN
iajs-4030	23	30	.	.	PUNCT
iajs-4030	24	1	38(3)2025	38(3)2025	NUM
iajs-4030	24	2	275	275	NUM
iajs-4030	24	3	a	a	DET
iajs-4030	24	4	serious	serious	ADJ
iajs-4030	24	5	role	role	NOUN
iajs-4030	24	6	in	in	ADP
iajs-4030	24	7	maintaining	maintain	VERB
iajs-4030	24	8	fluid	fluid	ADJ
iajs-4030	24	9	and	and	CCONJ
iajs-4030	24	10	electrolyte	electrolyte	NOUN
iajs-4030	24	11	balance	balance	NOUN
iajs-4030	24	12	and	and	CCONJ
iajs-4030	24	13	ultimately	ultimately	ADV
iajs-4030	24	14	preventing	prevent	VERB
iajs-4030	24	15	the	the	DET
iajs-4030	24	16	development	development	NOUN
iajs-4030	24	17	of	of	ADP
iajs-4030	24	18	end	end	NOUN
iajs-4030	24	19	-	-	PUNCT
iajs-4030	24	20	stage	stage	NOUN
iajs-4030	24	21	renal	renal	ADJ
iajs-4030	24	22	disease	disease	NOUN
iajs-4030	24	23	(	(	PUNCT
iajs-4030	24	24	esrd	esrd	PROPN
iajs-4030	24	25	)	)	PUNCT
iajs-4030	24	26	,	,	PUNCT
iajs-4030	24	27	primary	primary	ADJ
iajs-4030	24	28	diagnosis	diagnosis	NOUN
iajs-4030	24	29	and	and	CCONJ
iajs-4030	24	30	adequate	adequate	ADJ
iajs-4030	24	31	management	management	NOUN
iajs-4030	24	32	are	be	AUX
iajs-4030	24	33	imperative	imperative	ADJ
iajs-4030	24	34	.	.	PUNCT
iajs-4030	25	1	thus	thus	ADV
iajs-4030	25	2	,	,	PUNCT
iajs-4030	25	3	sustaining	sustain	VERB
iajs-4030	25	4	a	a	DET
iajs-4030	25	5	high	high	ADJ
iajs-4030	25	6	quality	quality	NOUN
iajs-4030	25	7	of	of	ADP
iajs-4030	25	8	life	life	NOUN
iajs-4030	25	9	requires	require	VERB
iajs-4030	25	10	prevention	prevention	NOUN
iajs-4030	25	11	and	and	CCONJ
iajs-4030	25	12	knowledge	knowledge	NOUN
iajs-4030	25	13	of	of	ADP
iajs-4030	25	14	this	this	DET
iajs-4030	25	15	disease	disease	NOUN
iajs-4030	25	16	(	(	PUNCT
iajs-4030	25	17	2,3	2,3	NUM
iajs-4030	25	18	)	)	PUNCT
iajs-4030	25	19	.	.	PUNCT
iajs-4030	26	1	essential	essential	ADJ
iajs-4030	26	2	kidney	kidney	NOUN
iajs-4030	26	3	functions	function	NOUN
iajs-4030	26	4	,	,	PUNCT
iajs-4030	26	5	including	include	VERB
iajs-4030	26	6	blood	blood	NOUN
iajs-4030	26	7	urea	urea	NOUN
iajs-4030	26	8	and	and	CCONJ
iajs-4030	26	9	creatinine	creatinine	NOUN
iajs-4030	26	10	levels	level	NOUN
iajs-4030	26	11	,	,	PUNCT
iajs-4030	26	12	are	be	AUX
iajs-4030	26	13	greatly	greatly	ADV
iajs-4030	26	14	impacted	impact	VERB
iajs-4030	26	15	by	by	ADP
iajs-4030	26	16	ckd	ckd	PROPN
iajs-4030	26	17	(	(	PUNCT
iajs-4030	26	18	4	4	NUM
iajs-4030	26	19	)	)	PUNCT
iajs-4030	26	20	.	.	PUNCT
iajs-4030	27	1	increased	increase	VERB
iajs-4030	27	2	blood	blood	NOUN
iajs-4030	27	3	urea	urea	NOUN
iajs-4030	27	4	levels	level	NOUN
iajs-4030	27	5	resulting	result	VERB
iajs-4030	27	6	from	from	ADP
iajs-4030	27	7	compromised	compromise	VERB
iajs-4030	27	8	renal	renal	ADJ
iajs-4030	27	9	function	function	NOUN
iajs-4030	27	10	may	may	AUX
iajs-4030	27	11	worsen	worsen	VERB
iajs-4030	27	12	overall	overall	ADJ
iajs-4030	27	13	health	health	NOUN
iajs-4030	27	14	and	and	CCONJ
iajs-4030	27	15	contribute	contribute	VERB
iajs-4030	27	16	to	to	ADP
iajs-4030	27	17	the	the	DET
iajs-4030	27	18	development	development	NOUN
iajs-4030	27	19	of	of	ADP
iajs-4030	27	20	hypertension	hypertension	NOUN
iajs-4030	27	21	(	(	PUNCT
iajs-4030	27	22	htn	htn	PROPN
iajs-4030	27	23	)	)	PUNCT
iajs-4030	27	24	(	(	PUNCT
iajs-4030	27	25	5	5	NUM
iajs-4030	27	26	)	)	PUNCT
iajs-4030	27	27	.	.	PUNCT
iajs-4030	28	1	due	due	ADP
iajs-4030	28	2	to	to	ADP
iajs-4030	28	3	its	its	PRON
iajs-4030	28	4	role	role	NOUN
iajs-4030	28	5	in	in	ADP
iajs-4030	28	6	muscle	muscle	NOUN
iajs-4030	28	7	metabolism	metabolism	NOUN
iajs-4030	28	8	,	,	PUNCT
iajs-4030	28	9	creatinine	creatinine	NOUN
iajs-4030	28	10	is	be	AUX
iajs-4030	28	11	a	a	DET
iajs-4030	28	12	sensitive	sensitive	ADJ
iajs-4030	28	13	marker	marker	NOUN
iajs-4030	28	14	of	of	ADP
iajs-4030	28	15	renal	renal	ADJ
iajs-4030	28	16	function	function	NOUN
iajs-4030	28	17	;	;	PUNCT
iajs-4030	28	18	higher	high	ADJ
iajs-4030	28	19	blood	blood	NOUN
iajs-4030	28	20	levels	level	NOUN
iajs-4030	28	21	indicate	indicate	VERB
iajs-4030	28	22	worse	bad	ADJ
iajs-4030	28	23	kidney	kidney	NOUN
iajs-4030	28	24	clearance	clearance	NOUN
iajs-4030	28	25	(	(	PUNCT
iajs-4030	28	26	6,7	6,7	NUM
iajs-4030	28	27	)	)	PUNCT
iajs-4030	28	28	.	.	PUNCT
iajs-4030	29	1	additionally	additionally	ADV
iajs-4030	29	2	,	,	PUNCT
iajs-4030	29	3	evaluating	evaluate	VERB
iajs-4030	29	4	the	the	DET
iajs-4030	29	5	glomerular	glomerular	ADJ
iajs-4030	29	6	filtration	filtration	NOUN
iajs-4030	29	7	rate	rate	NOUN
iajs-4030	29	8	(	(	PUNCT
iajs-4030	29	9	gfr	gfr	NOUN
iajs-4030	29	10	)	)	PUNCT
iajs-4030	29	11	reveals	reveal	VERB
iajs-4030	29	12	the	the	DET
iajs-4030	29	13	kidneys	kidney	NOUN
iajs-4030	29	14	'	'	PART
iajs-4030	29	15	role	role	NOUN
iajs-4030	29	16	in	in	ADP
iajs-4030	29	17	filtering	filter	VERB
iajs-4030	29	18	waste	waste	NOUN
iajs-4030	29	19	products	product	NOUN
iajs-4030	29	20	and	and	CCONJ
iajs-4030	29	21	toxins	toxin	NOUN
iajs-4030	29	22	from	from	ADP
iajs-4030	29	23	the	the	DET
iajs-4030	29	24	blood	blood	NOUN
iajs-4030	29	25	.	.	PUNCT
iajs-4030	30	1	a	a	DET
iajs-4030	30	2	reduced	reduce	VERB
iajs-4030	30	3	gfr	gfr	NOUN
iajs-4030	30	4	is	be	AUX
iajs-4030	30	5	indicative	indicative	ADJ
iajs-4030	30	6	of	of	ADP
iajs-4030	30	7	deteriorating	deteriorate	VERB
iajs-4030	30	8	ckd	ckd	NOUN
iajs-4030	30	9	and	and	CCONJ
iajs-4030	30	10	additional	additional	ADJ
iajs-4030	30	11	deterioration	deterioration	NOUN
iajs-4030	30	12	in	in	ADP
iajs-4030	30	13	kidney	kidney	NOUN
iajs-4030	30	14	function	function	NOUN
iajs-4030	30	15	,	,	PUNCT
iajs-4030	30	16	which	which	PRON
iajs-4030	30	17	worsens	worsen	VERB
iajs-4030	30	18	the	the	DET
iajs-4030	30	19	disease	disease	NOUN
iajs-4030	30	20	's	's	PART
iajs-4030	30	21	symptoms	symptom	NOUN
iajs-4030	30	22	and	and	CCONJ
iajs-4030	30	23	complications	complication	NOUN
iajs-4030	30	24	(	(	PUNCT
iajs-4030	30	25	8)	8)	NUM
iajs-4030	30	26	.	.	PUNCT
iajs-4030	31	1	it	it	PRON
iajs-4030	31	2	was	be	AUX
iajs-4030	31	3	first	first	ADV
iajs-4030	31	4	discovered	discover	VERB
iajs-4030	31	5	that	that	SCONJ
iajs-4030	31	6	microtubules	microtubule	NOUN
iajs-4030	31	7	(	(	PUNCT
iajs-4030	31	8	mts	mts	NOUN
iajs-4030	31	9	)	)	PUNCT
iajs-4030	31	10	were	be	AUX
iajs-4030	31	11	bound	bind	VERB
iajs-4030	31	12	and	and	CCONJ
iajs-4030	31	13	stabilized	stabilize	VERB
iajs-4030	31	14	by	by	ADP
iajs-4030	31	15	microtubule	microtubule	NOUN
iajs-4030	31	16	-	-	PUNCT
iajs-4030	31	17	associated	associate	VERB
iajs-4030	31	18	proteins	protein	NOUN
iajs-4030	31	19	(	(	PUNCT
iajs-4030	31	20	maps	map	NOUN
iajs-4030	31	21	)	)	PUNCT
iajs-4030	31	22	.	.	PUNCT
iajs-4030	32	1	nevertheless	nevertheless	ADV
iajs-4030	32	2	,	,	PUNCT
iajs-4030	32	3	research	research	NOUN
iajs-4030	32	4	is	be	AUX
iajs-4030	32	5	being	be	AUX
iajs-4030	32	6	conducted	conduct	VERB
iajs-4030	32	7	on	on	ADP
iajs-4030	32	8	their	their	PRON
iajs-4030	32	9	intricate	intricate	ADJ
iajs-4030	32	10	roles	role	NOUN
iajs-4030	32	11	as	as	ADP
iajs-4030	32	12	mt	mt	PROPN
iajs-4030	32	13	cytoskeleton	cytoskeleton	PROPN
iajs-4030	32	14	regulators	regulator	NOUN
iajs-4030	32	15	and	and	CCONJ
iajs-4030	32	16	their	their	PRON
iajs-4030	32	17	participation	participation	NOUN
iajs-4030	32	18	in	in	ADP
iajs-4030	32	19	various	various	ADJ
iajs-4030	32	20	cellular	cellular	ADJ
iajs-4030	32	21	processes	process	NOUN
iajs-4030	32	22	,	,	PUNCT
iajs-4030	32	23	such	such	ADJ
iajs-4030	32	24	as	as	ADP
iajs-4030	32	25	spindle	spindle	NOUN
iajs-4030	32	26	assembly	assembly	NOUN
iajs-4030	32	27	and	and	CCONJ
iajs-4030	32	28	neuronal	neuronal	ADJ
iajs-4030	32	29	development	development	NOUN
iajs-4030	32	30	(	(	PUNCT
iajs-4030	32	31	9	9	NUM
iajs-4030	32	32	)	)	PUNCT
iajs-4030	32	33	.	.	PUNCT
iajs-4030	33	1	in	in	ADP
iajs-4030	33	2	diabetic	diabetic	ADJ
iajs-4030	33	3	nephropathy	nephropathy	NOUN
iajs-4030	33	4	(	(	PUNCT
iajs-4030	33	5	dn	dn	NOUN
iajs-4030	33	6	)	)	PUNCT
iajs-4030	33	7	,	,	PUNCT
iajs-4030	33	8	disruption	disruption	NOUN
iajs-4030	33	9	of	of	ADP
iajs-4030	33	10	these	these	DET
iajs-4030	33	11	proteins	protein	NOUN
iajs-4030	33	12	triggers	trigger	VERB
iajs-4030	33	13	a	a	DET
iajs-4030	33	14	pathogenic	pathogenic	ADJ
iajs-4030	33	15	reaction	reaction	NOUN
iajs-4030	33	16	that	that	PRON
iajs-4030	33	17	reorganizes	reorganize	VERB
iajs-4030	33	18	the	the	DET
iajs-4030	33	19	cytoskeleton	cytoskeleton	NOUN
iajs-4030	33	20	of	of	ADP
iajs-4030	33	21	leg	leg	NOUN
iajs-4030	33	22	cells	cell	NOUN
iajs-4030	33	23	,	,	PUNCT
iajs-4030	33	24	breaks	break	VERB
iajs-4030	33	25	down	down	ADP
iajs-4030	33	26	connections	connection	NOUN
iajs-4030	33	27	,	,	PUNCT
iajs-4030	33	28	and	and	CCONJ
iajs-4030	33	29	acquires	acquire	VERB
iajs-4030	33	30	mesenchymal	mesenchymal	ADJ
iajs-4030	33	31	characteristics	characteristic	NOUN
iajs-4030	33	32	(	(	PUNCT
iajs-4030	33	33	10	10	NUM
iajs-4030	33	34	)	)	PUNCT
iajs-4030	33	35	.	.	PUNCT
iajs-4030	34	1	structural	structural	ADJ
iajs-4030	34	2	proteins	protein	NOUN
iajs-4030	34	3	called	call	VERB
iajs-4030	34	4	maps	map	NOUN
iajs-4030	34	5	bind	bind	VERB
iajs-4030	34	6	to	to	ADP
iajs-4030	34	7	tubulins	tubulin	NOUN
iajs-4030	34	8	,	,	PUNCT
iajs-4030	34	9	facilitating	facilitate	VERB
iajs-4030	34	10	assembly	assembly	NOUN
iajs-4030	34	11	.	.	PUNCT
iajs-4030	35	1	tau	tau	PROPN
iajs-4030	35	2	,	,	PUNCT
iajs-4030	35	3	map2	map2	NOUN
iajs-4030	35	4	,	,	PUNCT
iajs-4030	35	5	and	and	CCONJ
iajs-4030	35	6	map4	map4	NOUN
iajs-4030	35	7	belong	belong	VERB
iajs-4030	35	8	to	to	ADP
iajs-4030	35	9	the	the	DET
iajs-4030	35	10	classical	classical	ADJ
iajs-4030	35	11	family	family	NOUN
iajs-4030	35	12	of	of	ADP
iajs-4030	35	13	maps	map	NOUN
iajs-4030	35	14	.	.	PUNCT
iajs-4030	36	1	large	large	ADJ
iajs-4030	36	2	and	and	CCONJ
iajs-4030	36	3	small	small	ADJ
iajs-4030	36	4	proteins	protein	NOUN
iajs-4030	36	5	are	be	AUX
iajs-4030	36	6	essential	essential	ADJ
iajs-4030	36	7	for	for	ADP
iajs-4030	36	8	the	the	DET
iajs-4030	36	9	architecture	architecture	NOUN
iajs-4030	36	10	of	of	ADP
iajs-4030	36	11	the	the	DET
iajs-4030	36	12	cytoskeletal	cytoskeletal	ADJ
iajs-4030	36	13	network	network	NOUN
iajs-4030	36	14	in	in	ADP
iajs-4030	36	15	eukaryotic	eukaryotic	ADJ
iajs-4030	36	16	cells	cell	NOUN
iajs-4030	36	17	through	through	ADP
iajs-4030	36	18	their	their	PRON
iajs-4030	36	19	interactions	interaction	NOUN
iajs-4030	36	20	with	with	ADP
iajs-4030	36	21	maps	map	NOUN
iajs-4030	36	22	.	.	PUNCT
iajs-4030	37	1	cellular	cellular	ADJ
iajs-4030	37	2	functions	function	NOUN
iajs-4030	37	3	,	,	PUNCT
iajs-4030	37	4	such	such	ADJ
iajs-4030	37	5	as	as	ADP
iajs-4030	37	6	motility	motility	NOUN
iajs-4030	37	7	,	,	PUNCT
iajs-4030	37	8	trafficking	trafficking	NOUN
iajs-4030	37	9	,	,	PUNCT
iajs-4030	37	10	and	and	CCONJ
iajs-4030	37	11	division	division	NOUN
iajs-4030	37	12	,	,	PUNCT
iajs-4030	37	13	depend	depend	VERB
iajs-4030	37	14	on	on	ADP
iajs-4030	37	15	mts	mts	NOUN
iajs-4030	37	16	,	,	PUNCT
iajs-4030	37	17	which	which	PRON
iajs-4030	37	18	are	be	AUX
iajs-4030	37	19	organized	organize	VERB
iajs-4030	37	20	into	into	ADP
iajs-4030	37	21	discrete	discrete	ADJ
iajs-4030	37	22	arrays	array	NOUN
iajs-4030	37	23	with	with	ADP
iajs-4030	37	24	unique	unique	ADJ
iajs-4030	37	25	dynamics	dynamic	NOUN
iajs-4030	37	26	.	.	PUNCT
iajs-4030	38	1	they	they	PRON
iajs-4030	38	2	need	need	VERB
iajs-4030	38	3	maps	map	NOUN
iajs-4030	38	4	,	,	PUNCT
iajs-4030	38	5	which	which	PRON
iajs-4030	38	6	fall	fall	VERB
iajs-4030	38	7	into	into	ADP
iajs-4030	38	8	one	one	NUM
iajs-4030	38	9	of	of	ADP
iajs-4030	38	10	five	five	NUM
iajs-4030	38	11	categories	category	NOUN
iajs-4030	38	12	(	(	PUNCT
iajs-4030	38	13	11	11	NUM
iajs-4030	38	14	)	)	PUNCT
iajs-4030	38	15	.	.	PUNCT
iajs-4030	39	1	map2	map2	PROPN
iajs-4030	39	2	is	be	AUX
iajs-4030	39	3	required	require	VERB
iajs-4030	39	4	to	to	PART
iajs-4030	39	5	maintain	maintain	VERB
iajs-4030	39	6	the	the	DET
iajs-4030	39	7	structural	structural	ADJ
iajs-4030	39	8	stability	stability	NOUN
iajs-4030	39	9	of	of	ADP
iajs-4030	39	10	neural	neural	ADJ
iajs-4030	39	11	fibers	fiber	NOUN
iajs-4030	39	12	and	and	CCONJ
iajs-4030	39	13	mt	mt	PROPN
iajs-4030	39	14	dynamics	dynamic	NOUN
iajs-4030	39	15	within	within	ADP
iajs-4030	39	16	nerve	nerve	NOUN
iajs-4030	39	17	cells	cell	NOUN
iajs-4030	39	18	.	.	PUNCT
iajs-4030	40	1	although	although	SCONJ
iajs-4030	40	2	map2	map2	NOUN
iajs-4030	40	3	is	be	AUX
iajs-4030	40	4	predominantly	predominantly	ADV
iajs-4030	40	5	detected	detect	VERB
iajs-4030	40	6	in	in	ADP
iajs-4030	40	7	the	the	DET
iajs-4030	40	8	brain	brain	NOUN
iajs-4030	40	9	and	and	CCONJ
iajs-4030	40	10	central	central	ADJ
iajs-4030	40	11	nervous	nervous	ADJ
iajs-4030	40	12	system	system	NOUN
iajs-4030	40	13	,	,	PUNCT
iajs-4030	40	14	it	it	PRON
iajs-4030	40	15	can	can	AUX
iajs-4030	40	16	also	also	ADV
iajs-4030	40	17	be	be	AUX
iajs-4030	40	18	identified	identify	VERB
iajs-4030	40	19	in	in	ADP
iajs-4030	40	20	other	other	ADJ
iajs-4030	40	21	cells	cell	NOUN
iajs-4030	40	22	,	,	PUNCT
iajs-4030	40	23	such	such	ADJ
iajs-4030	40	24	as	as	ADP
iajs-4030	40	25	kidney	kidney	NOUN
iajs-4030	40	26	cells	cell	NOUN
iajs-4030	40	27	(	(	PUNCT
iajs-4030	40	28	12	12	NUM
iajs-4030	40	29	)	)	PUNCT
iajs-4030	40	30	.	.	PUNCT
iajs-4030	41	1	the	the	DET
iajs-4030	41	2	effects	effect	NOUN
iajs-4030	41	3	of	of	ADP
iajs-4030	41	4	oxidative	oxidative	ADJ
iajs-4030	41	5	stress	stress	NOUN
iajs-4030	41	6	and	and	CCONJ
iajs-4030	41	7	kidney	kidney	NOUN
iajs-4030	41	8	inflammation	inflammation	NOUN
iajs-4030	41	9	on	on	ADP
iajs-4030	41	10	renal	renal	ADJ
iajs-4030	41	11	cells	cell	NOUN
iajs-4030	41	12	linked	link	VERB
iajs-4030	41	13	to	to	ADP
iajs-4030	41	14	ckd	ckd	PROPN
iajs-4030	41	15	are	be	AUX
iajs-4030	41	16	the	the	DET
iajs-4030	41	17	main	main	ADJ
iajs-4030	41	18	mechanisms	mechanism	NOUN
iajs-4030	41	19	underlying	underlie	VERB
iajs-4030	41	20	the	the	DET
iajs-4030	41	21	relationship	relationship	NOUN
iajs-4030	41	22	between	between	ADP
iajs-4030	41	23	map2	map2	PROPN
iajs-4030	41	24	and	and	CCONJ
iajs-4030	41	25	ckd	ckd	PROPN
iajs-4030	41	26	(	(	PUNCT
iajs-4030	41	27	13	13	NUM
iajs-4030	41	28	)	)	PUNCT
iajs-4030	41	29	.	.	PUNCT
iajs-4030	42	1	for	for	ADP
iajs-4030	42	2	instance	instance	NOUN
iajs-4030	42	3	,	,	PUNCT
iajs-4030	42	4	damage	damage	NOUN
iajs-4030	42	5	from	from	ADP
iajs-4030	42	6	kidney	kidney	NOUN
iajs-4030	42	7	inflammation	inflammation	NOUN
iajs-4030	42	8	can	can	AUX
iajs-4030	42	9	lead	lead	VERB
iajs-4030	42	10	to	to	ADP
iajs-4030	42	11	changes	change	NOUN
iajs-4030	42	12	in	in	ADP
iajs-4030	42	13	map2	map2	ADJ
iajs-4030	42	14	expression	expression	NOUN
iajs-4030	42	15	,	,	PUNCT
iajs-4030	42	16	potentially	potentially	ADV
iajs-4030	42	17	contributing	contribute	VERB
iajs-4030	42	18	to	to	ADP
iajs-4030	42	19	cellular	cellular	ADJ
iajs-4030	42	20	dysfunction	dysfunction	NOUN
iajs-4030	42	21	and	and	CCONJ
iajs-4030	42	22	structural	structural	ADJ
iajs-4030	42	23	impairment	impairment	NOUN
iajs-4030	42	24	in	in	ADP
iajs-4030	42	25	kidney	kidney	NOUN
iajs-4030	42	26	tissues	tissue	NOUN
iajs-4030	42	27	(	(	PUNCT
iajs-4030	42	28	14	14	NUM
iajs-4030	42	29	)	)	PUNCT
iajs-4030	42	30	.	.	PUNCT
iajs-4030	43	1	hence	hence	ADV
iajs-4030	43	2	,	,	PUNCT
iajs-4030	43	3	this	this	DET
iajs-4030	43	4	study	study	NOUN
iajs-4030	43	5	aims	aim	VERB
iajs-4030	43	6	to	to	PART
iajs-4030	43	7	evaluate	evaluate	VERB
iajs-4030	43	8	the	the	DET
iajs-4030	43	9	role	role	NOUN
iajs-4030	43	10	of	of	ADP
iajs-4030	43	11	map2	map2	NOUN
iajs-4030	43	12	in	in	ADP
iajs-4030	43	13	evaluating	evaluate	VERB
iajs-4030	43	14	ckd	ckd	PROPN
iajs-4030	43	15	and	and	CCONJ
iajs-4030	43	16	its	its	PRON
iajs-4030	43	17	associated	associated	ADJ
iajs-4030	43	18	biochemical	biochemical	ADJ
iajs-4030	43	19	factors	factor	NOUN
iajs-4030	43	20	among	among	ADP
iajs-4030	43	21	iraqi	iraqi	ADJ
iajs-4030	43	22	patients	patient	NOUN
iajs-4030	43	23	.	.	PUNCT
iajs-4030	44	1	2	2	X
iajs-4030	44	2	.	.	X
iajs-4030	44	3	materials	material	NOUN
iajs-4030	44	4	and	and	CCONJ
iajs-4030	44	5	methods	method	NOUN
iajs-4030	44	6	2.1	2.1	NUM
iajs-4030	44	7	study	study	NOUN
iajs-4030	44	8	design	design	NOUN
iajs-4030	44	9	ninety	ninety	NUM
iajs-4030	44	10	individuals	individual	NOUN
iajs-4030	44	11	,	,	PUNCT
iajs-4030	44	12	aged	aged	ADJ
iajs-4030	44	13	48–65	48–65	NUM
iajs-4030	44	14	years	year	NOUN
iajs-4030	44	15	,	,	PUNCT
iajs-4030	44	16	were	be	AUX
iajs-4030	44	17	enrolled	enrol	VERB
iajs-4030	44	18	in	in	ADP
iajs-4030	44	19	this	this	DET
iajs-4030	44	20	study	study	NOUN
iajs-4030	44	21	from	from	ADP
iajs-4030	44	22	december	december	PROPN
iajs-4030	44	23	2023	2023	NUM
iajs-4030	44	24	to	to	PART
iajs-4030	44	25	may	may	PROPN
iajs-4030	44	26	2024	2024	NUM
iajs-4030	44	27	at	at	ADP
iajs-4030	44	28	baghdad	baghdad	PROPN
iajs-4030	44	29	teaching	teach	VERB
iajs-4030	44	30	hospital/	hospital/	NUM
iajs-4030	44	31	medical	medical	ADJ
iajs-4030	44	32	city/	city/	NUM
iajs-4030	44	33	dialysis	dialysis	NOUN
iajs-4030	44	34	unit	unit	NOUN
iajs-4030	44	35	in	in	ADP
iajs-4030	44	36	baghdad	baghdad	PROPN
iajs-4030	44	37	,	,	PUNCT
iajs-4030	44	38	iraq	iraq	PROPN
iajs-4030	44	39	,	,	PUNCT
iajs-4030	44	40	and	and	CCONJ
iajs-4030	44	41	participated	participate	VERB
iajs-4030	44	42	in	in	ADP
iajs-4030	44	43	this	this	DET
iajs-4030	44	44	study	study	NOUN
iajs-4030	44	45	;	;	PUNCT
iajs-4030	44	46	60	60	NUM
iajs-4030	44	47	patients	patient	NOUN
iajs-4030	44	48	with	with	ADP
iajs-4030	44	49	ckd	ckd	PROPN
iajs-4030	44	50	and	and	CCONJ
iajs-4030	44	51	30	30	NUM
iajs-4030	44	52	healthy	healthy	ADJ
iajs-4030	44	53	subjects	subject	NOUN
iajs-4030	44	54	as	as	ADP
iajs-4030	44	55	a	a	DET
iajs-4030	44	56	control	control	NOUN
iajs-4030	44	57	group	group	NOUN
iajs-4030	44	58	.	.	PUNCT
iajs-4030	45	1	a	a	DET
iajs-4030	45	2	questionnaire	questionnaire	NOUN
iajs-4030	45	3	containing	contain	VERB
iajs-4030	45	4	age	age	NOUN
iajs-4030	45	5	,	,	PUNCT
iajs-4030	45	6	height	height	NOUN
iajs-4030	45	7	,	,	PUNCT
iajs-4030	45	8	weight	weight	NOUN
iajs-4030	45	9	,	,	PUNCT
iajs-4030	45	10	and	and	CCONJ
iajs-4030	45	11	other	other	ADJ
iajs-4030	45	12	diseases	disease	NOUN
iajs-4030	45	13	was	be	AUX
iajs-4030	45	14	recorded	record	VERB
iajs-4030	45	15	;	;	PUNCT
iajs-4030	45	16	ckd	ckd	PROPN
iajs-4030	45	17	diagnosis	diagnosis	NOUN
iajs-4030	45	18	was	be	AUX
iajs-4030	45	19	confirmed	confirm	VERB
iajs-4030	45	20	based	base	VERB
iajs-4030	45	21	on	on	ADP
iajs-4030	45	22	egfr	egfr	NOUN
iajs-4030	45	23	calculated	calculate	VERB
iajs-4030	45	24	via	via	ADP
iajs-4030	45	25	the	the	DET
iajs-4030	45	26	ckd	ckd	PROPN
iajs-4030	45	27	-	-	PUNCT
iajs-4030	45	28	epi	epi	ADJ
iajs-4030	45	29	2021	2021	NUM
iajs-4030	45	30	equation	equation	NOUN
iajs-4030	45	31	,	,	PUNCT
iajs-4030	45	32	with	with	ADP
iajs-4030	45	33	values	value	NOUN
iajs-4030	45	34	≤	≤	NUM
iajs-4030	45	35	60	60	NUM
iajs-4030	45	36	ml	ml	NOUN
iajs-4030	45	37	/	/	SYM
iajs-4030	45	38	min/1.73	min/1.73	NOUN
iajs-4030	45	39	m²	m²	NOUN
iajs-4030	45	40	for	for	ADP
iajs-4030	45	41	at	at	ADV
iajs-4030	45	42	least	least	ADV
iajs-4030	45	43	3	3	NUM
iajs-4030	45	44	months	month	NOUN
iajs-4030	45	45	or	or	CCONJ
iajs-4030	45	46	evidence	evidence	NOUN
iajs-4030	45	47	of	of	ADP
iajs-4030	45	48	renal	renal	ADJ
iajs-4030	45	49	impairment	impairment	NOUN
iajs-4030	45	50	,	,	PUNCT
iajs-4030	45	51	such	such	ADJ
iajs-4030	45	52	as	as	ADP
iajs-4030	45	53	urinary	urinary	ADJ
iajs-4030	45	54	albumin	albumin	NOUN
iajs-4030	45	55	≥	≥	NUM
iajs-4030	45	56	30	30	NUM
iajs-4030	45	57	mg	mg	PROPN
iajs-4030	45	58	/	/	SYM
iajs-4030	45	59	g	g	NOUN
iajs-4030	45	60	creatinine	creatinine	NOUN
iajs-4030	45	61	(	(	PUNCT
iajs-4030	45	62	15	15	NUM
iajs-4030	45	63	)	)	PUNCT
iajs-4030	45	64	.	.	PUNCT
iajs-4030	46	1	2.2	2.2	NUM
iajs-4030	46	2	inclusion	inclusion	NOUN
iajs-4030	46	3	and	and	CCONJ
iajs-4030	46	4	exclusion	exclusion	NOUN
iajs-4030	46	5	criteria	criterion	NOUN
iajs-4030	46	6	inclusion	inclusion	NOUN
iajs-4030	46	7	criteria	criterion	NOUN
iajs-4030	46	8	were	be	AUX
iajs-4030	46	9	an	an	DET
iajs-4030	46	10	age	age	NOUN
iajs-4030	46	11	range	range	NOUN
iajs-4030	46	12	of	of	ADP
iajs-4030	46	13	48	48	NUM
iajs-4030	46	14	to	to	PART
iajs-4030	46	15	65	65	NUM
iajs-4030	46	16	with	with	ADP
iajs-4030	46	17	esrd	esrd	PROPN
iajs-4030	46	18	,	,	PUNCT
iajs-4030	46	19	who	who	PRON
iajs-4030	46	20	were	be	AUX
iajs-4030	46	21	on	on	ADP
iajs-4030	46	22	a	a	DET
iajs-4030	46	23	hemodialysis	hemodialysis	NOUN
iajs-4030	46	24	program	program	NOUN
iajs-4030	46	25	for	for	ADP
iajs-4030	46	26	at	at	ADV
iajs-4030	46	27	least	least	ADV
iajs-4030	46	28	6	6	NUM
iajs-4030	46	29	months	month	NOUN
iajs-4030	46	30	before	before	ADP
iajs-4030	46	31	recruitment	recruitment	NOUN
iajs-4030	46	32	.	.	PUNCT
iajs-4030	47	1	exclusion	exclusion	NOUN
iajs-4030	47	2	criteria	criterion	NOUN
iajs-4030	47	3	were	be	AUX
iajs-4030	47	4	aki	aki	NOUN
iajs-4030	47	5	,	,	PUNCT
iajs-4030	47	6	pregnancy	pregnancy	NOUN
iajs-4030	47	7	,	,	PUNCT
iajs-4030	47	8	type	type	NOUN
iajs-4030	47	9	1	1	NUM
iajs-4030	47	10	diabetes	diabetes	NOUN
iajs-4030	47	11	,	,	PUNCT
iajs-4030	47	12	liver	liver	NOUN
iajs-4030	47	13	disease	disease	NOUN
iajs-4030	47	14	,	,	PUNCT
iajs-4030	47	15	thyroid	thyroid	NOUN
iajs-4030	47	16	dysfunction	dysfunction	NOUN
iajs-4030	47	17	,	,	PUNCT
iajs-4030	47	18	and	and	CCONJ
iajs-4030	47	19	malignancy	malignancy	NOUN
iajs-4030	47	20	.	.	PUNCT
iajs-4030	48	1	ihjpas	ihjpas	PROPN
iajs-4030	48	2	.	.	PUNCT
iajs-4030	49	1	38(3)2025	38(3)2025	NUM
iajs-4030	49	2	276	276	NUM
iajs-4030	49	3	2.3	2.3	NUM
iajs-4030	49	4	biochemical	biochemical	ADJ
iajs-4030	49	5	analysis	analysis	NOUN
iajs-4030	49	6	each	each	DET
iajs-4030	49	7	participant	participant	NOUN
iajs-4030	49	8	's	's	PART
iajs-4030	49	9	sex	sex	NOUN
iajs-4030	49	10	,	,	PUNCT
iajs-4030	49	11	age	age	NOUN
iajs-4030	49	12	,	,	PUNCT
iajs-4030	49	13	weight	weight	NOUN
iajs-4030	49	14	,	,	PUNCT
iajs-4030	49	15	height	height	NOUN
iajs-4030	49	16	,	,	PUNCT
iajs-4030	49	17	body	body	NOUN
iajs-4030	49	18	mass	mass	NOUN
iajs-4030	49	19	index	index	NOUN
iajs-4030	49	20	(	(	PUNCT
iajs-4030	49	21	bmi	bmi	PROPN
iajs-4030	49	22	)	)	PUNCT
iajs-4030	49	23	,	,	PUNCT
iajs-4030	49	24	and	and	CCONJ
iajs-4030	49	25	systolic	systolic	ADJ
iajs-4030	49	26	and	and	CCONJ
iajs-4030	49	27	diastolic	diastolic	ADJ
iajs-4030	49	28	blood	blood	NOUN
iajs-4030	49	29	pressure	pressure	NOUN
iajs-4030	49	30	(	(	PUNCT
iajs-4030	49	31	sbp	sbp	NOUN
iajs-4030	49	32	and	and	CCONJ
iajs-4030	49	33	dbp	dbp	PROPN
iajs-4030	49	34	,	,	PUNCT
iajs-4030	49	35	respectively	respectively	ADV
iajs-4030	49	36	)	)	PUNCT
iajs-4030	49	37	were	be	AUX
iajs-4030	49	38	measured	measure	VERB
iajs-4030	49	39	,	,	PUNCT
iajs-4030	49	40	along	along	ADP
iajs-4030	49	41	with	with	ADP
iajs-4030	49	42	other	other	ADJ
iajs-4030	49	43	anthropometric	anthropometric	ADJ
iajs-4030	49	44	and	and	CCONJ
iajs-4030	49	45	clinical	clinical	ADJ
iajs-4030	49	46	data	datum	NOUN
iajs-4030	49	47	.	.	PUNCT
iajs-4030	50	1	a	a	DET
iajs-4030	50	2	biochemical	biochemical	ADJ
iajs-4030	50	3	automated	automate	VERB
iajs-4030	50	4	analyzer	analyzer	NOUN
iajs-4030	50	5	(	(	PUNCT
iajs-4030	50	6	cobas	cobas	PROPN
iajs-4030	50	7	e411	e411	PROPN
iajs-4030	50	8	)	)	PUNCT
iajs-4030	50	9	was	be	AUX
iajs-4030	50	10	used	use	VERB
iajs-4030	50	11	to	to	PART
iajs-4030	50	12	test	test	VERB
iajs-4030	50	13	the	the	DET
iajs-4030	50	14	fsg	fsg	PROPN
iajs-4030	50	15	and	and	CCONJ
iajs-4030	50	16	renal	renal	ADJ
iajs-4030	50	17	function	function	NOUN
iajs-4030	50	18	test	test	NOUN
iajs-4030	50	19	levels	level	NOUN
iajs-4030	50	20	,	,	PUNCT
iajs-4030	50	21	including	include	VERB
iajs-4030	50	22	serum	serum	NOUN
iajs-4030	50	23	urea	urea	NOUN
iajs-4030	50	24	,	,	PUNCT
iajs-4030	50	25	creatinine	creatinine	NOUN
iajs-4030	50	26	,	,	PUNCT
iajs-4030	50	27	total	total	ADJ
iajs-4030	50	28	protein	protein	NOUN
iajs-4030	50	29	,	,	PUNCT
iajs-4030	50	30	and	and	CCONJ
iajs-4030	50	31	albumin	albumin	ADJ
iajs-4030	50	32	levels	level	NOUN
iajs-4030	50	33	.	.	PUNCT
iajs-4030	51	1	glycated	glycate	VERB
iajs-4030	51	2	hemoglobin	hemoglobin	NOUN
iajs-4030	51	3	(	(	PUNCT
iajs-4030	51	4	hba1c	hba1c	PROPN
iajs-4030	51	5	)	)	PUNCT
iajs-4030	51	6	was	be	AUX
iajs-4030	51	7	measured	measure	VERB
iajs-4030	51	8	by	by	ADP
iajs-4030	51	9	the	the	DET
iajs-4030	51	10	bio	bio	PROPN
iajs-4030	51	11	-	-	ADJ
iajs-4030	51	12	rad	rad	ADJ
iajs-4030	51	13	variant	variant	ADJ
iajs-4030	51	14	hemoglobin	hemoglobin	NOUN
iajs-4030	51	15	a1c	a1c	PROPN
iajs-4030	51	16	.	.	PUNCT
iajs-4030	52	1	the	the	DET
iajs-4030	52	2	egfr	egfr	NOUN
iajs-4030	52	3	was	be	AUX
iajs-4030	52	4	calculated	calculate	VERB
iajs-4030	52	5	using	use	VERB
iajs-4030	52	6	the	the	DET
iajs-4030	52	7	ckd	ckd	NOUN
iajs-4030	52	8	-	-	PUNCT
iajs-4030	52	9	epi	epi	NOUN
iajs-4030	52	10	formula	formula	NOUN
iajs-4030	52	11	(	(	PUNCT
iajs-4030	52	12	16	16	NUM
iajs-4030	52	13	)	)	PUNCT
iajs-4030	52	14	.	.	PUNCT
iajs-4030	53	1	egfr=	egfr=	NUM
iajs-4030	53	2	144	144	NUM
iajs-4030	53	3	×	×	NOUN
iajs-4030	53	4	(	(	PUNCT
iajs-4030	53	5	scr/0.7	scr/0.7	PROPN
iajs-4030	53	6	)	)	PUNCT
iajs-4030	53	7	-1.209	-1.209	PUNCT
iajs-4030	53	8	×(0.993	×(0.993	SYM
iajs-4030	53	9	)	)	PUNCT
iajs-4030	53	10	age	age	NOUN
iajs-4030	53	11	(	(	PUNCT
iajs-4030	53	12	1	1	NUM
iajs-4030	53	13	)	)	PUNCT
iajs-4030	54	1	[	[	X
iajs-4030	54	2	for	for	ADP
iajs-4030	54	3	women	woman	NOUN
iajs-4030	54	4	and	and	CCONJ
iajs-4030	54	5	serum	serum	NOUN
iajs-4030	54	6	creatinine	creatinine	PROPN
iajs-4030	54	7	>	>	X
iajs-4030	54	8	0.7	0.7	NUM
iajs-4030	54	9	mg	mg	PROPN
iajs-4030	54	10	/	/	SYM
iajs-4030	54	11	dl	dl	X
iajs-4030	54	12	]	]	X
iajs-4030	54	13	egfr=	egfr=	NUM
iajs-4030	54	14	141	141	NUM
iajs-4030	54	15	×	×	NOUN
iajs-4030	54	16	(	(	PUNCT
iajs-4030	54	17	scr/0.9	scr/0.9	PROPN
iajs-4030	54	18	)	)	PUNCT
iajs-4030	54	19	-1.209	-1.209	NOUN
iajs-4030	54	20	×	×	NOUN
iajs-4030	54	21	(	(	PUNCT
iajs-4030	54	22	0.993	0.993	NUM
iajs-4030	54	23	)	)	PUNCT
iajs-4030	54	24	age	age	NOUN
iajs-4030	54	25	(	(	PUNCT
iajs-4030	54	26	2	2	NUM
iajs-4030	54	27	)	)	PUNCT
iajs-4030	54	28	[	[	X
iajs-4030	54	29	for	for	ADP
iajs-4030	54	30	men	man	NOUN
iajs-4030	54	31	and	and	CCONJ
iajs-4030	54	32	serum	serum	NOUN
iajs-4030	54	33	creatinine	creatinine	PROPN
iajs-4030	54	34	>	>	X
iajs-4030	54	35	0.9	0.9	NUM
iajs-4030	54	36	mg	mg	PROPN
iajs-4030	54	37	/	/	SYM
iajs-4030	54	38	dl	dl	PROPN
iajs-4030	54	39	]	]	X
iajs-4030	54	40	.	.	PUNCT
iajs-4030	55	1	additionally	additionally	ADV
iajs-4030	55	2	,	,	PUNCT
iajs-4030	55	3	serum	serum	NOUN
iajs-4030	55	4	map2	map2	NOUN
iajs-4030	55	5	level	level	NOUN
iajs-4030	55	6	was	be	AUX
iajs-4030	55	7	measured	measure	VERB
iajs-4030	55	8	using	use	VERB
iajs-4030	55	9	a	a	DET
iajs-4030	55	10	sandwich	sandwich	NOUN
iajs-4030	55	11	enzyme	enzyme	NOUN
iajs-4030	55	12	immunoassay	immunoassay	ADJ
iajs-4030	55	13	kit	kit	NOUN
iajs-4030	55	14	from	from	ADP
iajs-4030	55	15	elabscience	elabscience	NOUN
iajs-4030	55	16	,	,	PUNCT
iajs-4030	55	17	usa	usa	PROPN
iajs-4030	55	18	(	(	PUNCT
iajs-4030	55	19	cat	cat	NOUN
iajs-4030	55	20	no	no	NOUN
iajs-4030	55	21	:	:	PUNCT
iajs-4030	55	22	e	e	X
iajs-4030	55	23	-	-	PROPN
iajs-4030	55	24	el	el	NOUN
iajs-4030	55	25	-	-	PUNCT
iajs-4030	55	26	h2539	h2539	NOUN
iajs-4030	55	27	)	)	PUNCT
iajs-4030	55	28	;	;	PUNCT
iajs-4030	55	29	the	the	DET
iajs-4030	55	30	sensitivity	sensitivity	NOUN
iajs-4030	55	31	was	be	AUX
iajs-4030	55	32	18.75	18.75	NUM
iajs-4030	55	33	ρg	ρg	NOUN
iajs-4030	55	34	/	/	SYM
iajs-4030	55	35	ml	ml	NOUN
iajs-4030	55	36	,	,	PUNCT
iajs-4030	55	37	with	with	ADP
iajs-4030	55	38	a	a	DET
iajs-4030	55	39	detection	detection	NOUN
iajs-4030	55	40	range	range	NOUN
iajs-4030	55	41	of	of	ADP
iajs-4030	55	42	31.25	31.25	NUM
iajs-4030	55	43	-	-	SYM
iajs-4030	55	44	2000	2000	NUM
iajs-4030	55	45	pg	pg	NOUN
iajs-4030	55	46	/	/	SYM
iajs-4030	55	47	ml	ml	NOUN
iajs-4030	55	48	.	.	NOUN
iajs-4030	56	1	2.4	2.4	NUM
iajs-4030	56	2	statistical	statistical	ADJ
iajs-4030	56	3	analysis	analysis	NOUN
iajs-4030	56	4	the	the	DET
iajs-4030	56	5	statistical	statistical	ADJ
iajs-4030	56	6	package	package	NOUN
iajs-4030	56	7	for	for	ADP
iajs-4030	56	8	the	the	DET
iajs-4030	56	9	social	social	ADJ
iajs-4030	56	10	sciences	science	NOUN
iajs-4030	56	11	(	(	PUNCT
iajs-4030	56	12	spss)-ibm	spss)-ibm	PROPN
iajs-4030	56	13	29	29	NUM
iajs-4030	56	14	,	,	PUNCT
iajs-4030	56	15	chicago	chicago	PROPN
iajs-4030	56	16	,	,	PUNCT
iajs-4030	56	17	usa	usa	PROPN
iajs-4030	56	18	was	be	AUX
iajs-4030	56	19	used	use	VERB
iajs-4030	56	20	to	to	PART
iajs-4030	56	21	analyze	analyze	VERB
iajs-4030	56	22	the	the	DET
iajs-4030	56	23	data	datum	NOUN
iajs-4030	56	24	.	.	PUNCT
iajs-4030	57	1	all	all	DET
iajs-4030	57	2	results	result	NOUN
iajs-4030	57	3	were	be	AUX
iajs-4030	57	4	shown	show	VERB
iajs-4030	57	5	as	as	SCONJ
iajs-4030	57	6	means	mean	VERB
iajs-4030	57	7	±	±	NUM
iajs-4030	57	8	standard	standard	ADJ
iajs-4030	57	9	deviation	deviation	NOUN
iajs-4030	57	10	(	(	PUNCT
iajs-4030	57	11	sd	sd	NOUN
iajs-4030	57	12	)	)	PUNCT
iajs-4030	57	13	.	.	PUNCT
iajs-4030	58	1	the	the	DET
iajs-4030	58	2	chi	chi	ADJ
iajs-4030	58	3	-	-	PUNCT
iajs-4030	58	4	square	square	ADJ
iajs-4030	58	5	test	test	NOUN
iajs-4030	58	6	was	be	AUX
iajs-4030	58	7	used	use	VERB
iajs-4030	58	8	to	to	PART
iajs-4030	58	9	compare	compare	VERB
iajs-4030	58	10	percentage	percentage	NOUN
iajs-4030	58	11	values	value	NOUN
iajs-4030	58	12	.	.	PUNCT
iajs-4030	59	1	the	the	DET
iajs-4030	59	2	independent	independent	ADJ
iajs-4030	59	3	samples	sample	NOUN
iajs-4030	59	4	t	t	NOUN
iajs-4030	59	5	-	-	PUNCT
iajs-4030	59	6	test	test	NOUN
iajs-4030	59	7	was	be	AUX
iajs-4030	59	8	used	use	VERB
iajs-4030	59	9	to	to	PART
iajs-4030	59	10	compare	compare	VERB
iajs-4030	59	11	numerical	numerical	ADJ
iajs-4030	59	12	variables	variable	NOUN
iajs-4030	59	13	between	between	ADP
iajs-4030	59	14	two	two	NUM
iajs-4030	59	15	groups	group	NOUN
iajs-4030	59	16	.	.	PUNCT
iajs-4030	60	1	also	also	ADV
iajs-4030	60	2	,	,	PUNCT
iajs-4030	60	3	the	the	DET
iajs-4030	60	4	correlation	correlation	NOUN
iajs-4030	60	5	coefficient	coefficient	NOUN
iajs-4030	60	6	(	(	PUNCT
iajs-4030	60	7	r	r	NOUN
iajs-4030	60	8	)	)	PUNCT
iajs-4030	60	9	between	between	ADP
iajs-4030	60	10	map2	map2	PROPN
iajs-4030	60	11	and	and	CCONJ
iajs-4030	60	12	other	other	ADJ
iajs-4030	60	13	study	study	NOUN
iajs-4030	60	14	parameters	parameter	NOUN
iajs-4030	60	15	in	in	ADP
iajs-4030	60	16	the	the	DET
iajs-4030	60	17	ckd	ckd	PROPN
iajs-4030	60	18	group	group	NOUN
iajs-4030	60	19	was	be	AUX
iajs-4030	60	20	determined	determine	VERB
iajs-4030	60	21	.	.	PUNCT
iajs-4030	61	1	a	a	DET
iajs-4030	61	2	p	p	NOUN
iajs-4030	61	3	-	-	PUNCT
iajs-4030	61	4	value	value	NOUN
iajs-4030	61	5	<	<	X
iajs-4030	61	6	0.05	0.05	NUM
iajs-4030	61	7	was	be	AUX
iajs-4030	61	8	considered	consider	VERB
iajs-4030	61	9	significant	significant	ADJ
iajs-4030	61	10	(	(	PUNCT
iajs-4030	61	11	17	17	NUM
iajs-4030	61	12	)	)	PUNCT
iajs-4030	61	13	.	.	PUNCT
iajs-4030	62	1	3	3	X
iajs-4030	62	2	.	.	NOUN
iajs-4030	62	3	results	result	VERB
iajs-4030	62	4	body	body	PROPN
iajs-4030	62	5	mass	mass	PROPN
iajs-4030	62	6	index	index	PROPN
iajs-4030	62	7	,	,	PUNCT
iajs-4030	62	8	sbp	sbp	NOUN
iajs-4030	62	9	,	,	PUNCT
iajs-4030	62	10	and	and	CCONJ
iajs-4030	62	11	dbp	dbp	PROPN
iajs-4030	62	12	were	be	AUX
iajs-4030	62	13	significantly	significantly	ADV
iajs-4030	62	14	(	(	PUNCT
iajs-4030	62	15	p	p	X
iajs-4030	62	16	<	<	X
iajs-4030	62	17	0.05	0.05	NUM
iajs-4030	62	18	)	)	PUNCT
iajs-4030	62	19	elevated	elevate	VERB
iajs-4030	62	20	in	in	ADP
iajs-4030	62	21	ckd	ckd	PROPN
iajs-4030	62	22	patients	patient	NOUN
iajs-4030	62	23	compared	compare	VERB
iajs-4030	62	24	to	to	ADP
iajs-4030	62	25	controls	control	NOUN
iajs-4030	62	26	,	,	PUNCT
iajs-4030	62	27	as	as	SCONJ
iajs-4030	62	28	shown	show	VERB
iajs-4030	62	29	in	in	ADP
iajs-4030	62	30	table	table	NOUN
iajs-4030	62	31	(	(	PUNCT
iajs-4030	62	32	1	1	NUM
iajs-4030	62	33	)	)	PUNCT
iajs-4030	62	34	.	.	PUNCT
iajs-4030	63	1	table	table	NOUN
iajs-4030	63	2	1	1	NUM
iajs-4030	63	3	.	.	PUNCT
iajs-4030	64	1	demographic	demographic	ADJ
iajs-4030	64	2	,	,	PUNCT
iajs-4030	64	3	anthropometric	anthropometric	ADJ
iajs-4030	64	4	,	,	PUNCT
iajs-4030	64	5	and	and	CCONJ
iajs-4030	64	6	clinical	clinical	ADJ
iajs-4030	64	7	manifestations	manifestation	NOUN
iajs-4030	64	8	of	of	ADP
iajs-4030	64	9	the	the	DET
iajs-4030	64	10	studied	study	VERB
iajs-4030	64	11	groups	group	NOUN
iajs-4030	64	12	p	p	X
iajs-4030	64	13	<	<	X
iajs-4030	64	14	0.05	0.05	NUM
iajs-4030	64	15	:	:	PUNCT
iajs-4030	64	16	significant	significant	ADJ
iajs-4030	64	17	.	.	PUNCT
iajs-4030	65	1	patients	patient	NOUN
iajs-4030	65	2	'	'	PART
iajs-4030	65	3	fsg	fsg	PROPN
iajs-4030	65	4	,	,	PUNCT
iajs-4030	65	5	urea	urea	NOUN
iajs-4030	65	6	,	,	PUNCT
iajs-4030	65	7	and	and	CCONJ
iajs-4030	65	8	creatinine	creatinine	NOUN
iajs-4030	65	9	showed	show	VERB
iajs-4030	65	10	significant	significant	ADJ
iajs-4030	65	11	increases	increase	NOUN
iajs-4030	65	12	(	(	PUNCT
iajs-4030	65	13	p=	p=	NOUN
iajs-4030	65	14	0.001	0.001	NUM
iajs-4030	65	15	)	)	PUNCT
iajs-4030	65	16	compared	compare	VERB
iajs-4030	65	17	to	to	ADP
iajs-4030	65	18	the	the	DET
iajs-4030	65	19	controls	control	NOUN
iajs-4030	65	20	.	.	PUNCT
iajs-4030	66	1	serum	serum	NOUN
iajs-4030	66	2	total	total	ADJ
iajs-4030	66	3	protein	protein	NOUN
iajs-4030	66	4	,	,	PUNCT
iajs-4030	66	5	albumin	albumin	ADJ
iajs-4030	66	6	levels	level	NOUN
iajs-4030	66	7	,	,	PUNCT
iajs-4030	66	8	and	and	CCONJ
iajs-4030	66	9	egfr	egfr	NOUN
iajs-4030	66	10	decreased	decrease	VERB
iajs-4030	66	11	considerably	considerably	ADV
iajs-4030	66	12	(	(	PUNCT
iajs-4030	66	13	p=	p=	NOUN
iajs-4030	66	14	0.001	0.001	NUM
iajs-4030	66	15	)	)	PUNCT
iajs-4030	66	16	in	in	ADP
iajs-4030	66	17	the	the	DET
iajs-4030	66	18	ckd	ckd	PROPN
iajs-4030	66	19	group	group	NOUN
iajs-4030	66	20	compared	compare	VERB
iajs-4030	66	21	to	to	ADP
iajs-4030	66	22	the	the	DET
iajs-4030	66	23	controls	control	NOUN
iajs-4030	66	24	,	,	PUNCT
iajs-4030	66	25	as	as	SCONJ
iajs-4030	66	26	shown	show	VERB
iajs-4030	66	27	in	in	ADP
iajs-4030	66	28	table	table	NOUN
iajs-4030	66	29	(	(	PUNCT
iajs-4030	66	30	2	2	NUM
iajs-4030	66	31	)	)	PUNCT
iajs-4030	66	32	.	.	PUNCT
iajs-4030	67	1	moreover	moreover	ADV
iajs-4030	67	2	,	,	PUNCT
iajs-4030	67	3	table	table	NOUN
iajs-4030	67	4	(	(	PUNCT
iajs-4030	67	5	3	3	X
iajs-4030	67	6	)	)	PUNCT
iajs-4030	67	7	reveals	reveal	VERB
iajs-4030	67	8	significantly	significantly	ADV
iajs-4030	67	9	higher	higher	ADV
iajs-4030	67	10	(	(	PUNCT
iajs-4030	67	11	p=	p=	NOUN
iajs-4030	67	12	0.0001	0.0001	NUM
iajs-4030	67	13	)	)	PUNCT
iajs-4030	67	14	levels	level	NOUN
iajs-4030	67	15	of	of	ADP
iajs-4030	67	16	map-2	map-2	PUNCT
iajs-4030	67	17	in	in	ADP
iajs-4030	67	18	ckd	ckd	NOUN
iajs-4030	67	19	patients	patient	NOUN
iajs-4030	67	20	compared	compare	VERB
iajs-4030	67	21	to	to	ADP
iajs-4030	67	22	the	the	DET
iajs-4030	67	23	controls	control	NOUN
iajs-4030	67	24	.	.	PUNCT
iajs-4030	68	1	additionally	additionally	ADV
iajs-4030	68	2	,	,	PUNCT
iajs-4030	68	3	current	current	ADJ
iajs-4030	68	4	outcomes	outcome	NOUN
iajs-4030	68	5	reveal	reveal	VERB
iajs-4030	68	6	a	a	DET
iajs-4030	68	7	significant	significant	ADJ
iajs-4030	68	8	(	(	PUNCT
iajs-4030	68	9	p	p	X
iajs-4030	68	10	<	<	X
iajs-4030	68	11	0.05	0.05	NUM
iajs-4030	68	12	)	)	PUNCT
iajs-4030	68	13	positive	positive	ADJ
iajs-4030	68	14	correlation	correlation	NOUN
iajs-4030	68	15	between	between	ADP
iajs-4030	68	16	map2	map2	PROPN
iajs-4030	68	17	and	and	CCONJ
iajs-4030	68	18	various	various	ADJ
iajs-4030	68	19	parameter	parameter	NOUN
iajs-4030	68	20	levels	level	NOUN
iajs-4030	68	21	,	,	PUNCT
iajs-4030	68	22	including	include	VERB
iajs-4030	68	23	fsg	fsg	PROPN
iajs-4030	68	24	,	,	PUNCT
iajs-4030	68	25	urea	urea	NOUN
iajs-4030	68	26	,	,	PUNCT
iajs-4030	68	27	and	and	CCONJ
iajs-4030	68	28	creatinine	creatinine	NOUN
iajs-4030	68	29	.	.	PUNCT
iajs-4030	69	1	also	also	ADV
iajs-4030	69	2	,	,	PUNCT
iajs-4030	69	3	the	the	DET
iajs-4030	69	4	current	current	ADJ
iajs-4030	69	5	results	result	NOUN
iajs-4030	69	6	indicate	indicate	VERB
iajs-4030	69	7	a	a	DET
iajs-4030	69	8	significant	significant	ADJ
iajs-4030	69	9	(	(	PUNCT
iajs-4030	69	10	p	p	X
iajs-4030	69	11	<	<	X
iajs-4030	69	12	0.05	0.05	NUM
iajs-4030	69	13	)	)	PUNCT
iajs-4030	69	14	negative	negative	ADJ
iajs-4030	69	15	correlation	correlation	NOUN
iajs-4030	69	16	between	between	ADP
iajs-4030	69	17	map2	map2	NOUN
iajs-4030	69	18	levels	level	NOUN
iajs-4030	69	19	and	and	CCONJ
iajs-4030	69	20	serum	serum	NOUN
iajs-4030	69	21	parameters	parameter	NOUN
iajs-4030	69	22	mean	mean	VERB
iajs-4030	69	23	±	±	NUM
iajs-4030	69	24	sd	sd	ADP
iajs-4030	69	25	p	p	NOUN
iajs-4030	69	26	-	-	PUNCT
iajs-4030	69	27	value	value	NOUN
iajs-4030	69	28	ckd	ckd	PROPN
iajs-4030	69	29	control	control	NOUN
iajs-4030	69	30	number	number	NOUN
iajs-4030	69	31	60	60	NUM
iajs-4030	69	32	30	30	NUM
iajs-4030	69	33	male/	male/	PROPN
iajs-4030	69	34	femal	femal	NOUN
iajs-4030	69	35	no	no	INTJ
iajs-4030	69	36	.	.	PUNCT
iajs-4030	70	1	(	(	PUNCT
iajs-4030	70	2	%	%	NOUN
iajs-4030	70	3	)	)	PUNCT
iajs-4030	70	4	38(63%)/22(37	38(63%)/22(37	NUM
iajs-4030	70	5	%	%	NOUN
iajs-4030	70	6	)	)	PUNCT
iajs-4030	70	7	15(50%)/15(50	15(50%)/15(50	NUM
iajs-4030	70	8	%	%	NOUN
iajs-4030	70	9	)	)	PUNCT
iajs-4030	70	10	0.001	0.001	NUM
iajs-4030	70	11	age	age	NOUN
iajs-4030	70	12	(	(	PUNCT
iajs-4030	70	13	years	year	NOUN
iajs-4030	70	14	)	)	PUNCT
iajs-4030	70	15	55.60	55.60	NUM
iajs-4030	70	16	±	±	NUM
iajs-4030	70	17	10.22	10.22	NUM
iajs-4030	70	18	53.43	53.43	NUM
iajs-4030	70	19	±	±	NUM
iajs-4030	70	20	5.46	5.46	NUM
iajs-4030	70	21	0.06	0.06	NUM
iajs-4030	70	22	bmi	bmi	NOUN
iajs-4030	70	23	(	(	PUNCT
iajs-4030	70	24	kg	kg	NOUN
iajs-4030	70	25	/	/	SYM
iajs-4030	70	26	m	m	VERB
iajs-4030	70	27	2	2	NUM
iajs-4030	70	28	)	)	PUNCT
iajs-4030	70	29	30.52	30.52	NUM
iajs-4030	70	30	±	±	NUM
iajs-4030	70	31	2.14	2.14	NUM
iajs-4030	70	32	24.85	24.85	NUM
iajs-4030	70	33	±	±	NUM
iajs-4030	70	34	1.12	1.12	NUM
iajs-4030	70	35	0.001	0.001	NUM
iajs-4030	70	36	sbp	sbp	NOUN
iajs-4030	70	37	(	(	PUNCT
iajs-4030	70	38	mmhg	mmhg	PROPN
iajs-4030	70	39	)	)	PUNCT
iajs-4030	70	40	152.30	152.30	NUM
iajs-4030	70	41	±	±	NUM
iajs-4030	70	42	2.41	2.41	NUM
iajs-4030	70	43	120.60	120.60	NUM
iajs-4030	70	44	±	±	NUM
iajs-4030	70	45	0.21	0.21	NUM
iajs-4030	70	46	0.001	0.001	NUM
iajs-4030	70	47	dbp	dbp	PROPN
iajs-4030	70	48	(	(	PUNCT
iajs-4030	70	49	mmhg	mmhg	PROPN
iajs-4030	70	50	)	)	PUNCT
iajs-4030	70	51	90.21±	90.21±	NUM
iajs-4030	70	52	1.87	1.87	NUM
iajs-4030	70	53	82.15	82.15	NUM
iajs-4030	70	54	±	±	NUM
iajs-4030	70	55	1.02	1.02	NUM
iajs-4030	70	56	0.030	0.030	NUM
iajs-4030	70	57	causes	cause	NOUN
iajs-4030	70	58	or	or	CCONJ
iajs-4030	70	59	other	other	ADJ
iajs-4030	70	60	disease	disease	NOUN
iajs-4030	70	61	:	:	PUNCT
iajs-4030	70	62	dn	dn	PROPN
iajs-4030	70	63	primary	primary	ADJ
iajs-4030	70	64	nephritis	nephritis	NOUN
iajs-4030	70	65	htn	htn	PROPN
iajs-4030	70	66	35(58	35(58	NUM
iajs-4030	70	67	%	%	NOUN
iajs-4030	70	68	)	)	PUNCT
iajs-4030	70	69	14(23	14(23	NOUN
iajs-4030	70	70	%	%	NOUN
iajs-4030	70	71	)	)	PUNCT
iajs-4030	71	1	40(66	40(66	NUM
iajs-4030	71	2	%	%	NOUN
iajs-4030	71	3	)	)	PUNCT
iajs-4030	71	4	ihjpas	ihjpas	PROPN
iajs-4030	71	5	.	.	PUNCT
iajs-4030	72	1	38(3)2025	38(3)2025	NUM
iajs-4030	72	2	277	277	NUM
iajs-4030	72	3	total	total	ADJ
iajs-4030	72	4	protein	protein	NOUN
iajs-4030	72	5	,	,	PUNCT
iajs-4030	72	6	albumin	albumin	NOUN
iajs-4030	72	7	,	,	PUNCT
iajs-4030	72	8	and	and	CCONJ
iajs-4030	72	9	egfr	egfr	NOUN
iajs-4030	72	10	.	.	PUNCT
iajs-4030	73	1	additionally	additionally	ADV
iajs-4030	73	2	,	,	PUNCT
iajs-4030	73	3	no	no	DET
iajs-4030	73	4	considerable	considerable	ADJ
iajs-4030	73	5	correlation	correlation	NOUN
iajs-4030	73	6	was	be	AUX
iajs-4030	73	7	detected	detect	VERB
iajs-4030	73	8	between	between	ADP
iajs-4030	73	9	the	the	DET
iajs-4030	73	10	serum	serum	NOUN
iajs-4030	73	11	map2	map2	PROPN
iajs-4030	73	12	levels	level	NOUN
iajs-4030	73	13	and	and	CCONJ
iajs-4030	73	14	hba1c	hba1c	NOUN
iajs-4030	73	15	,	,	PUNCT
iajs-4030	73	16	as	as	SCONJ
iajs-4030	73	17	presented	present	VERB
iajs-4030	73	18	in	in	ADP
iajs-4030	73	19	table	table	NOUN
iajs-4030	73	20	(	(	PUNCT
iajs-4030	73	21	4	4	NUM
iajs-4030	73	22	)	)	PUNCT
iajs-4030	73	23	.	.	PUNCT
iajs-4030	74	1	table	table	NOUN
iajs-4030	74	2	2	2	NUM
iajs-4030	74	3	.	.	PUNCT
iajs-4030	75	1	glycemic	glycemic	ADJ
iajs-4030	75	2	profiles	profile	NOUN
iajs-4030	75	3	and	and	CCONJ
iajs-4030	75	4	renal	renal	ADJ
iajs-4030	75	5	function	function	NOUN
iajs-4030	75	6	tests	test	NOUN
iajs-4030	75	7	of	of	ADP
iajs-4030	75	8	the	the	DET
iajs-4030	75	9	studied	study	VERB
iajs-4030	75	10	groups	group	NOUN
iajs-4030	75	11	parameters	parameter	NOUN
iajs-4030	75	12	mean	mean	VERB
iajs-4030	75	13	±	±	NUM
iajs-4030	75	14	sd	sd	ADP
iajs-4030	75	15	pvalue	pvalue	NOUN
iajs-4030	75	16	ckd	ckd	PROPN
iajs-4030	75	17	(	(	PUNCT
iajs-4030	75	18	n=	n=	ADJ
iajs-4030	75	19	60	60	NUM
iajs-4030	75	20	)	)	PUNCT
iajs-4030	75	21	control	control	NOUN
iajs-4030	75	22	(	(	PUNCT
iajs-4030	75	23	n=	n=	ADJ
iajs-4030	75	24	30	30	NUM
iajs-4030	75	25	)	)	PUNCT
iajs-4030	75	26	fsg	fsg	NOUN
iajs-4030	75	27	(	(	PUNCT
iajs-4030	75	28	mg	mg	PROPN
iajs-4030	75	29	/	/	SYM
iajs-4030	75	30	dl	dl	NOUN
iajs-4030	75	31	)	)	PUNCT
iajs-4030	75	32	158.44	158.44	NUM
iajs-4030	75	33	±	±	NUM
iajs-4030	75	34	17.26	17.26	NUM
iajs-4030	75	35	98.20	98.20	NUM
iajs-4030	75	36	±	±	NUM
iajs-4030	75	37	5.31	5.31	NUM
iajs-4030	75	38	0.001	0.001	NUM
iajs-4030	75	39	hba1c	hba1c	PROPN
iajs-4030	75	40	(	(	PUNCT
iajs-4030	75	41	%	%	INTJ
iajs-4030	75	42	)	)	PUNCT
iajs-4030	75	43	8.25	8.25	NUM
iajs-4030	75	44	±	±	NUM
iajs-4030	75	45	1.12	1.12	NUM
iajs-4030	75	46	5.67	5.67	NUM
iajs-4030	75	47	±	±	NUM
iajs-4030	75	48	0.08	0.08	NUM
iajs-4030	75	49	0.06	0.06	NUM
iajs-4030	75	50	urea	urea	NOUN
iajs-4030	75	51	(	(	PUNCT
iajs-4030	75	52	mg	mg	PROPN
iajs-4030	75	53	/	/	SYM
iajs-4030	75	54	dl	dl	PROPN
iajs-4030	75	55	)	)	PUNCT
iajs-4030	75	56	135.40	135.40	NUM
iajs-4030	75	57	±	±	NUM
iajs-4030	75	58	8.45	8.45	NUM
iajs-4030	75	59	20.05	20.05	NUM
iajs-4030	75	60	±	±	NUM
iajs-4030	75	61	1.12	1.12	NUM
iajs-4030	75	62	0.001	0.001	NUM
iajs-4030	75	63	creatinine	creatinine	NOUN
iajs-4030	75	64	(	(	PUNCT
iajs-4030	75	65	mg	mg	PROPN
iajs-4030	75	66	/	/	SYM
iajs-4030	75	67	dl	dl	PROPN
iajs-4030	75	68	)	)	PUNCT
iajs-4030	75	69	10.13	10.13	NUM
iajs-4030	75	70	±	±	NUM
iajs-4030	75	71	0.82	0.82	NUM
iajs-4030	75	72	0.62	0.62	NUM
iajs-4030	75	73	±	±	NUM
iajs-4030	75	74	0.01	0.01	NUM
iajs-4030	75	75	0.001	0.001	NUM
iajs-4030	75	76	total	total	ADJ
iajs-4030	75	77	protein	protein	NOUN
iajs-4030	75	78	(	(	PUNCT
iajs-4030	75	79	g	g	PROPN
iajs-4030	75	80	/	/	SYM
iajs-4030	75	81	dl	dl	NOUN
iajs-4030	75	82	)	)	PUNCT
iajs-4030	75	83	3.77	3.77	NUM
iajs-4030	75	84	±	±	NUM
iajs-4030	75	85	1.40	1.40	NUM
iajs-4030	75	86	6.80	6.80	NUM
iajs-4030	75	87	±	±	NUM
iajs-4030	75	88	1.25	1.25	NUM
iajs-4030	75	89	0.001	0.001	NUM
iajs-4030	75	90	albumin	albumin	NOUN
iajs-4030	75	91	(	(	PUNCT
iajs-4030	75	92	g	g	PROPN
iajs-4030	75	93	/	/	SYM
iajs-4030	75	94	dl	dl	NOUN
iajs-4030	75	95	)	)	PUNCT
iajs-4030	75	96	2.78	2.78	NUM
iajs-4030	75	97	±	±	NUM
iajs-4030	75	98	1.24	1.24	NUM
iajs-4030	75	99	4.50	4.50	NUM
iajs-4030	75	100	±	±	NUM
iajs-4030	75	101	1.12	1.12	NUM
iajs-4030	75	102	0.001	0.001	NUM
iajs-4030	75	103	egfr	egfr	NOUN
iajs-4030	75	104	(	(	PUNCT
iajs-4030	75	105	ml	ml	NOUN
iajs-4030	75	106	/	/	SYM
iajs-4030	75	107	min/1.73	min/1.73	NOUN
iajs-4030	75	108	m	m	VERB
iajs-4030	75	109	2	2	NUM
iajs-4030	75	110	)	)	PUNCT
iajs-4030	75	111	23.72	23.72	NUM
iajs-4030	75	112	±	±	NUM
iajs-4030	75	113	7.70	7.70	NUM
iajs-4030	75	114	105.80	105.80	NUM
iajs-4030	75	115	±	±	NUM
iajs-4030	75	116	5.06	5.06	NUM
iajs-4030	75	117	0.001	0.001	NUM
iajs-4030	75	118	p	p	X
iajs-4030	75	119	<	<	X
iajs-4030	75	120	0.05	0.05	NUM
iajs-4030	75	121	:	:	PUNCT
iajs-4030	75	122	significant	significant	ADJ
iajs-4030	75	123	.	.	PUNCT
iajs-4030	75	124	table	table	NOUN
iajs-4030	76	1	3	3	NUM
iajs-4030	76	2	.	.	PUNCT
iajs-4030	76	3	serum	serum	PROPN
iajs-4030	76	4	map2	map2	PROPN
iajs-4030	76	5	of	of	ADP
iajs-4030	76	6	the	the	DET
iajs-4030	76	7	studied	study	VERB
iajs-4030	76	8	groups	group	NOUN
iajs-4030	76	9	parameters	parameter	NOUN
iajs-4030	76	10	mean	mean	VERB
iajs-4030	76	11	±	±	NUM
iajs-4030	76	12	sd	sd	ADP
iajs-4030	76	13	pvalue	pvalue	NOUN
iajs-4030	76	14	ckd	ckd	PROPN
iajs-4030	76	15	(	(	PUNCT
iajs-4030	76	16	n=	n=	ADJ
iajs-4030	76	17	60	60	NUM
iajs-4030	76	18	)	)	PUNCT
iajs-4030	76	19	control	control	NOUN
iajs-4030	76	20	(	(	PUNCT
iajs-4030	76	21	n=	n=	ADJ
iajs-4030	76	22	30	30	NUM
iajs-4030	76	23	)	)	PUNCT
iajs-4030	76	24	map2	map2	NOUN
iajs-4030	76	25	(	(	PUNCT
iajs-4030	76	26	ρg	ρg	NOUN
iajs-4030	76	27	/	/	SYM
iajs-4030	76	28	ml	ml	VERB
iajs-4030	76	29	)	)	PUNCT
iajs-4030	76	30	616.10	616.10	NUM
iajs-4030	76	31	±	±	NUM
iajs-4030	76	32	12.25	12.25	NUM
iajs-4030	76	33	125.48	125.48	NUM
iajs-4030	76	34	±	±	NUM
iajs-4030	76	35	10.14	10.14	NUM
iajs-4030	76	36	0.0001	0.0001	NUM
iajs-4030	76	37	p	p	NOUN
iajs-4030	76	38	<	<	X
iajs-4030	76	39	0.05	0.05	NUM
iajs-4030	76	40	:	:	PUNCT
iajs-4030	76	41	significant	significant	ADJ
iajs-4030	76	42	.	.	PUNCT
iajs-4030	77	1	table	table	NOUN
iajs-4030	77	2	4	4	NUM
iajs-4030	77	3	.	.	PUNCT
iajs-4030	78	1	correlation	correlation	NOUN
iajs-4030	78	2	coefficient	coefficient	NOUN
iajs-4030	78	3	between	between	ADP
iajs-4030	78	4	map2	map2	PROPN
iajs-4030	78	5	and	and	CCONJ
iajs-4030	78	6	other	other	ADJ
iajs-4030	78	7	study	study	NOUN
iajs-4030	78	8	parameters	parameter	NOUN
iajs-4030	78	9	in	in	ADP
iajs-4030	78	10	the	the	DET
iajs-4030	78	11	ckd	ckd	PROPN
iajs-4030	78	12	group	group	PROPN
iajs-4030	78	13	parameters	parameter	NOUN
iajs-4030	78	14	map2	map2	PROPN
iajs-4030	78	15	(	(	PUNCT
iajs-4030	78	16	ρg	ρg	NOUN
iajs-4030	78	17	/	/	SYM
iajs-4030	78	18	ml	ml	NOUN
iajs-4030	78	19	)	)	PUNCT
iajs-4030	78	20	r	r	NOUN
iajs-4030	78	21	p	p	X
iajs-4030	78	22	fsg	fsg	PROPN
iajs-4030	78	23	(	(	PUNCT
iajs-4030	78	24	mg	mg	PROPN
iajs-4030	78	25	/	/	SYM
iajs-4030	78	26	dl	dl	PROPN
iajs-4030	78	27	)	)	PUNCT
iajs-4030	78	28	0.540	0.540	NUM
iajs-4030	78	29	0.001	0.001	NUM
iajs-4030	78	30	hba1c	hba1c	PROPN
iajs-4030	78	31	(	(	PUNCT
iajs-4030	78	32	%	%	INTJ
iajs-4030	78	33	)	)	PUNCT
iajs-4030	78	34	0.145	0.145	NUM
iajs-4030	78	35	0.08	0.08	NUM
iajs-4030	78	36	urea	urea	NOUN
iajs-4030	78	37	(	(	PUNCT
iajs-4030	78	38	mg	mg	PROPN
iajs-4030	78	39	/	/	SYM
iajs-4030	78	40	dl	dl	NOUN
iajs-4030	78	41	)	)	PUNCT
iajs-4030	78	42	0.358	0.358	NUM
iajs-4030	78	43	0.005	0.005	NUM
iajs-4030	78	44	creatinine	creatinine	NOUN
iajs-4030	78	45	(	(	PUNCT
iajs-4030	78	46	mg	mg	PROPN
iajs-4030	78	47	/	/	SYM
iajs-4030	78	48	dl	dl	PROPN
iajs-4030	78	49	)	)	PUNCT
iajs-4030	78	50	0.650	0.650	NUM
iajs-4030	78	51	0.001	0.001	NUM
iajs-4030	78	52	total	total	ADJ
iajs-4030	78	53	protein	protein	NOUN
iajs-4030	78	54	(	(	PUNCT
iajs-4030	78	55	g	g	PROPN
iajs-4030	78	56	/	/	SYM
iajs-4030	78	57	dl	dl	NOUN
iajs-4030	78	58	)	)	PUNCT
iajs-4030	78	59	-0.432	-0.432	NOUN
iajs-4030	78	60	0.001	0.001	NUM
iajs-4030	78	61	albumin	albumin	NOUN
iajs-4030	78	62	(	(	PUNCT
iajs-4030	78	63	g	g	PROPN
iajs-4030	78	64	/	/	SYM
iajs-4030	78	65	dl	dl	NOUN
iajs-4030	78	66	)	)	PUNCT
iajs-4030	78	67	-0.348	-0.348	PROPN
iajs-4030	78	68	0.030	0.030	NUM
iajs-4030	78	69	egfr	egfr	NOUN
iajs-4030	78	70	(	(	PUNCT
iajs-4030	78	71	ml	ml	NOUN
iajs-4030	78	72	/	/	SYM
iajs-4030	78	73	min/1.73	min/1.73	NOUN
iajs-4030	78	74	m	m	VERB
iajs-4030	78	75	2	2	NUM
iajs-4030	78	76	)	)	PUNCT
iajs-4030	78	77	-0.520	-0.520	NUM
iajs-4030	78	78	0.001	0.001	NUM
iajs-4030	78	79	p	p	X
iajs-4030	78	80	<	<	X
iajs-4030	78	81	0.05	0.05	NUM
iajs-4030	78	82	:	:	PUNCT
iajs-4030	78	83	significant	significant	ADJ
iajs-4030	78	84	.	.	PUNCT
iajs-4030	79	1	4	4	X
iajs-4030	79	2	.	.	X
iajs-4030	79	3	discussion	discussion	NOUN
iajs-4030	79	4	a	a	DET
iajs-4030	79	5	primary	primary	ADJ
iajs-4030	79	6	global	global	ADJ
iajs-4030	79	7	public	public	ADJ
iajs-4030	79	8	health	health	NOUN
iajs-4030	79	9	concern	concern	NOUN
iajs-4030	79	10	that	that	PRON
iajs-4030	79	11	affects	affect	VERB
iajs-4030	79	12	millions	million	NOUN
iajs-4030	79	13	of	of	ADP
iajs-4030	79	14	individuals	individual	NOUN
iajs-4030	79	15	is	be	AUX
iajs-4030	79	16	ckd	ckd	PROPN
iajs-4030	79	17	.	.	PUNCT
iajs-4030	80	1	it	it	PRON
iajs-4030	80	2	is	be	AUX
iajs-4030	80	3	linked	link	VERB
iajs-4030	80	4	to	to	ADP
iajs-4030	80	5	higher	high	ADJ
iajs-4030	80	6	death	death	NOUN
iajs-4030	80	7	rates	rate	NOUN
iajs-4030	80	8	and	and	CCONJ
iajs-4030	80	9	concomitant	concomitant	ADJ
iajs-4030	80	10	diseases	disease	NOUN
iajs-4030	80	11	,	,	PUNCT
iajs-4030	80	12	such	such	ADJ
iajs-4030	80	13	as	as	ADP
iajs-4030	80	14	cvd	cvd	PROPN
iajs-4030	80	15	(	(	PUNCT
iajs-4030	80	16	18	18	NUM
iajs-4030	80	17	)	)	PUNCT
iajs-4030	80	18	.	.	PUNCT
iajs-4030	81	1	the	the	DET
iajs-4030	81	2	current	current	ADJ
iajs-4030	81	3	data	datum	NOUN
iajs-4030	81	4	analysis	analysis	NOUN
iajs-4030	81	5	of	of	ADP
iajs-4030	81	6	the	the	DET
iajs-4030	81	7	biological	biological	ADJ
iajs-4030	81	8	and	and	CCONJ
iajs-4030	81	9	behavioral	behavioral	ADJ
iajs-4030	81	10	components	component	NOUN
iajs-4030	81	11	revealed	reveal	VERB
iajs-4030	81	12	that	that	SCONJ
iajs-4030	81	13	the	the	DET
iajs-4030	81	14	risk	risk	NOUN
iajs-4030	81	15	of	of	ADP
iajs-4030	81	16	developing	develop	VERB
iajs-4030	81	17	ckd	ckd	PROPN
iajs-4030	81	18	was	be	AUX
iajs-4030	81	19	significantly	significantly	ADV
iajs-4030	81	20	associated	associate	VERB
iajs-4030	81	21	with	with	ADP
iajs-4030	81	22	patients	patient	NOUN
iajs-4030	81	23	aged	age	VERB
iajs-4030	81	24	40	40	NUM
iajs-4030	81	25	to	to	PART
iajs-4030	81	26	65	65	NUM
iajs-4030	81	27	years	year	NOUN
iajs-4030	81	28	.	.	PUNCT
iajs-4030	82	1	this	this	PRON
iajs-4030	82	2	suggests	suggest	VERB
iajs-4030	82	3	that	that	SCONJ
iajs-4030	82	4	kidney	kidney	NOUN
iajs-4030	82	5	function	function	NOUN
iajs-4030	82	6	typically	typically	ADV
iajs-4030	82	7	diminishes	diminish	VERB
iajs-4030	82	8	with	with	ADP
iajs-4030	82	9	age	age	NOUN
iajs-4030	82	10	.	.	PUNCT
iajs-4030	83	1	after	after	ADP
iajs-4030	83	2	age	age	NOUN
iajs-4030	83	3	30	30	NUM
iajs-4030	83	4	,	,	PUNCT
iajs-4030	83	5	the	the	DET
iajs-4030	83	6	gfr	gfr	PROPN
iajs-4030	83	7	,	,	PUNCT
iajs-4030	83	8	a	a	DET
iajs-4030	83	9	crucial	crucial	ADJ
iajs-4030	83	10	measure	measure	NOUN
iajs-4030	83	11	of	of	ADP
iajs-4030	83	12	renal	renal	ADJ
iajs-4030	83	13	function	function	NOUN
iajs-4030	83	14	,	,	PUNCT
iajs-4030	83	15	progressively	progressively	ADV
iajs-4030	83	16	declines	decline	VERB
iajs-4030	83	17	(	(	PUNCT
iajs-4030	83	18	19,20	19,20	NOUN
iajs-4030	83	19	)	)	PUNCT
iajs-4030	83	20	.	.	PUNCT
iajs-4030	84	1	this	this	DET
iajs-4030	84	2	decrease	decrease	NOUN
iajs-4030	84	3	intensifies	intensify	VERB
iajs-4030	84	4	by	by	ADP
iajs-4030	84	5	the	the	DET
iajs-4030	84	6	age	age	NOUN
iajs-4030	84	7	of	of	ADP
iajs-4030	84	8	forty	forty	NUM
iajs-4030	84	9	.	.	PUNCT
iajs-4030	85	1	as	as	ADP
iajs-4030	85	2	people	people	NOUN
iajs-4030	85	3	age	age	NOUN
iajs-4030	85	4	,	,	PUNCT
iajs-4030	85	5	this	this	DET
iajs-4030	85	6	progressive	progressive	ADJ
iajs-4030	85	7	loss	loss	NOUN
iajs-4030	85	8	of	of	ADP
iajs-4030	85	9	kidney	kidney	NOUN
iajs-4030	85	10	function	function	NOUN
iajs-4030	85	11	is	be	AUX
iajs-4030	85	12	a	a	DET
iajs-4030	85	13	significant	significant	ADJ
iajs-4030	85	14	risk	risk	NOUN
iajs-4030	85	15	for	for	ADP
iajs-4030	85	16	developing	develop	VERB
iajs-4030	85	17	ckd	ckd	PROPN
iajs-4030	85	18	(	(	PUNCT
iajs-4030	85	19	21	21	NUM
iajs-4030	85	20	)	)	PUNCT
iajs-4030	85	21	.	.	PUNCT
iajs-4030	86	1	several	several	ADJ
iajs-4030	86	2	biological	biological	ADJ
iajs-4030	86	3	factors	factor	NOUN
iajs-4030	86	4	make	make	VERB
iajs-4030	86	5	individuals	individual	NOUN
iajs-4030	86	6	aged	age	VERB
iajs-4030	86	7	40	40	NUM
iajs-4030	86	8	to	to	PART
iajs-4030	86	9	65	65	NUM
iajs-4030	86	10	more	more	ADV
iajs-4030	86	11	susceptible	susceptible	ADJ
iajs-4030	86	12	to	to	ADP
iajs-4030	86	13	ckd	ckd	PROPN
iajs-4030	86	14	,	,	PUNCT
iajs-4030	86	15	such	such	ADJ
iajs-4030	86	16	as	as	ADP
iajs-4030	86	17	htn	htn	NOUN
iajs-4030	86	18	and	and	CCONJ
iajs-4030	86	19	diabetes	diabetes	NOUN
iajs-4030	86	20	,	,	PUNCT
iajs-4030	86	21	which	which	PRON
iajs-4030	86	22	increase	increase	VERB
iajs-4030	86	23	with	with	ADP
iajs-4030	86	24	age	age	NOUN
iajs-4030	86	25	(	(	PUNCT
iajs-4030	86	26	22	22	NUM
iajs-4030	86	27	)	)	PUNCT
iajs-4030	86	28	.	.	PUNCT
iajs-4030	87	1	diabetes	diabetes	NOUN
iajs-4030	87	2	and	and	CCONJ
iajs-4030	87	3	htn	htn	PROPN
iajs-4030	87	4	are	be	AUX
iajs-4030	87	5	major	major	ADJ
iajs-4030	87	6	contributors	contributor	NOUN
iajs-4030	87	7	to	to	ADP
iajs-4030	87	8	ckd	ckd	PROPN
iajs-4030	87	9	,	,	PUNCT
iajs-4030	87	10	which	which	PRON
iajs-4030	87	11	is	be	AUX
iajs-4030	87	12	likely	likely	ADV
iajs-4030	87	13	found	find	VERB
iajs-4030	87	14	in	in	ADP
iajs-4030	87	15	patients	patient	NOUN
iajs-4030	87	16	aged	age	VERB
iajs-4030	87	17	40	40	NUM
iajs-4030	87	18	to	to	PART
iajs-4030	87	19	65	65	NUM
iajs-4030	87	20	years	year	NOUN
iajs-4030	87	21	,	,	PUNCT
iajs-4030	87	22	as	as	SCONJ
iajs-4030	87	23	people	people	NOUN
iajs-4030	87	24	between	between	ADP
iajs-4030	87	25	these	these	DET
iajs-4030	87	26	ages	age	NOUN
iajs-4030	87	27	are	be	AUX
iajs-4030	87	28	more	more	ADV
iajs-4030	87	29	likely	likely	ADJ
iajs-4030	87	30	to	to	PART
iajs-4030	87	31	develop	develop	VERB
iajs-4030	87	32	these	these	DET
iajs-4030	87	33	illnesses	illness	NOUN
iajs-4030	87	34	or	or	CCONJ
iajs-4030	87	35	have	have	VERB
iajs-4030	87	36	persistent	persistent	ADJ
iajs-4030	87	37	instances	instance	NOUN
iajs-4030	87	38	that	that	PRON
iajs-4030	87	39	lead	lead	VERB
iajs-4030	87	40	to	to	ADP
iajs-4030	87	41	an	an	DET
iajs-4030	87	42	increased	increase	VERB
iajs-4030	87	43	risk	risk	NOUN
iajs-4030	87	44	of	of	ADP
iajs-4030	87	45	ckd	ckd	PROPN
iajs-4030	87	46	(	(	PUNCT
iajs-4030	87	47	23	23	NUM
iajs-4030	87	48	)	)	PUNCT
iajs-4030	87	49	.	.	PUNCT
iajs-4030	88	1	these	these	DET
iajs-4030	88	2	disorders	disorder	NOUN
iajs-4030	88	3	are	be	AUX
iajs-4030	88	4	substantial	substantial	ADJ
iajs-4030	88	5	risk	risk	NOUN
iajs-4030	88	6	factors	factor	NOUN
iajs-4030	88	7	for	for	ADP
iajs-4030	88	8	developing	develop	VERB
iajs-4030	88	9	ckd	ckd	PROPN
iajs-4030	88	10	.	.	PUNCT
iajs-4030	89	1	people	people	NOUN
iajs-4030	89	2	between	between	ADP
iajs-4030	89	3	the	the	DET
iajs-4030	89	4	ages	age	NOUN
iajs-4030	89	5	of	of	ADP
iajs-4030	89	6	40	40	NUM
iajs-4030	89	7	and	and	CCONJ
iajs-4030	89	8	65	65	NUM
iajs-4030	89	9	are	be	AUX
iajs-4030	89	10	more	more	ADV
iajs-4030	89	11	likely	likely	ADJ
iajs-4030	89	12	to	to	PART
iajs-4030	89	13	develop	develop	VERB
iajs-4030	89	14	these	these	DET
iajs-4030	89	15	illnesses	illness	NOUN
iajs-4030	89	16	or	or	CCONJ
iajs-4030	89	17	have	have	VERB
iajs-4030	89	18	persistent	persistent	ADJ
iajs-4030	89	19	instances	instance	NOUN
iajs-4030	89	20	,	,	PUNCT
iajs-4030	89	21	which	which	PRON
iajs-4030	89	22	raises	raise	VERB
iajs-4030	89	23	their	their	PRON
iajs-4030	89	24	risk	risk	NOUN
iajs-4030	89	25	of	of	ADP
iajs-4030	89	26	ckd	ckd	PROPN
iajs-4030	89	27	.	.	PUNCT
iajs-4030	90	1	the	the	DET
iajs-4030	90	2	aging	age	VERB
iajs-4030	90	3	process	process	NOUN
iajs-4030	90	4	leads	lead	VERB
iajs-4030	90	5	to	to	ADP
iajs-4030	90	6	cellular	cellular	ADJ
iajs-4030	90	7	changes	change	NOUN
iajs-4030	90	8	that	that	PRON
iajs-4030	90	9	damage	damage	VERB
iajs-4030	90	10	the	the	DET
iajs-4030	90	11	kidneys	kidney	NOUN
iajs-4030	90	12	,	,	PUNCT
iajs-4030	90	13	including	include	VERB
iajs-4030	90	14	decreased	decrease	VERB
iajs-4030	90	15	cellular	cellular	ADJ
iajs-4030	90	16	efficiency	efficiency	NOUN
iajs-4030	90	17	and	and	CCONJ
iajs-4030	90	18	increased	increase	VERB
iajs-4030	90	19	renal	renal	ADJ
iajs-4030	90	20	fibrosis	fibrosis	NOUN
iajs-4030	90	21	.	.	PUNCT
iajs-4030	91	1	these	these	DET
iajs-4030	91	2	alterations	alteration	NOUN
iajs-4030	91	3	diminish	diminish	VERB
iajs-4030	91	4	the	the	DET
iajs-4030	91	5	kidneys	kidney	NOUN
iajs-4030	91	6	'	'	PART
iajs-4030	91	7	resistance	resistance	NOUN
iajs-4030	91	8	to	to	ADP
iajs-4030	91	9	illness	illness	NOUN
iajs-4030	91	10	and	and	CCONJ
iajs-4030	91	11	damage	damage	NOUN
iajs-4030	91	12	(	(	PUNCT
iajs-4030	91	13	24	24	NUM
iajs-4030	91	14	)	)	PUNCT
iajs-4030	91	15	.	.	PUNCT
iajs-4030	92	1	ihjpas	ihjpas	PROPN
iajs-4030	92	2	.	.	PUNCT
iajs-4030	93	1	38(3)2025	38(3)2025	NUM
iajs-4030	93	2	278	278	NUM
iajs-4030	93	3	reduced	reduce	VERB
iajs-4030	93	4	physical	physical	ADJ
iajs-4030	93	5	activity	activity	NOUN
iajs-4030	93	6	also	also	ADV
iajs-4030	93	7	harms	harm	VERB
iajs-4030	93	8	cv	cv	PROPN
iajs-4030	93	9	health	health	NOUN
iajs-4030	93	10	and	and	CCONJ
iajs-4030	93	11	could	could	AUX
iajs-4030	93	12	induce	induce	VERB
iajs-4030	93	13	additional	additional	ADJ
iajs-4030	93	14	load	load	NOUN
iajs-4030	93	15	on	on	ADP
iajs-4030	93	16	the	the	DET
iajs-4030	93	17	kidneys	kidney	NOUN
iajs-4030	93	18	(	(	PUNCT
iajs-4030	93	19	25	25	NUM
iajs-4030	93	20	)	)	PUNCT
iajs-4030	93	21	.	.	PUNCT
iajs-4030	94	1	kidney	kidney	NOUN
iajs-4030	94	2	function	function	NOUN
iajs-4030	94	3	is	be	AUX
iajs-4030	94	4	impacted	impact	VERB
iajs-4030	94	5	by	by	ADP
iajs-4030	94	6	cvd	cvd	PROPN
iajs-4030	94	7	,	,	PUNCT
iajs-4030	94	8	which	which	PRON
iajs-4030	94	9	is	be	AUX
iajs-4030	94	10	elevated	elevate	VERB
iajs-4030	94	11	by	by	ADP
iajs-4030	94	12	smoking	smoke	VERB
iajs-4030	94	13	as	as	ADV
iajs-4030	94	14	well	well	ADV
iajs-4030	94	15	as	as	ADP
iajs-4030	94	16	long	long	ADJ
iajs-4030	94	17	-	-	PUNCT
iajs-4030	94	18	term	term	NOUN
iajs-4030	94	19	alcohol	alcohol	NOUN
iajs-4030	94	20	use/	use/	ADJ
iajs-4030	94	21	alcohol	alcohol	NOUN
iajs-4030	94	22	disorders	disorder	NOUN
iajs-4030	94	23	that	that	PRON
iajs-4030	94	24	can	can	AUX
iajs-4030	94	25	directly	directly	ADV
iajs-4030	94	26	affect	affect	VERB
iajs-4030	94	27	the	the	DET
iajs-4030	94	28	kidneys	kidney	NOUN
iajs-4030	94	29	.	.	PUNCT
iajs-4030	95	1	a	a	DET
iajs-4030	95	2	lengthy	lengthy	ADJ
iajs-4030	95	3	history	history	NOUN
iajs-4030	95	4	of	of	ADP
iajs-4030	95	5	these	these	DET
iajs-4030	95	6	detrimental	detrimental	ADJ
iajs-4030	95	7	practices	practice	NOUN
iajs-4030	95	8	may	may	AUX
iajs-4030	95	9	increase	increase	VERB
iajs-4030	95	10	the	the	DET
iajs-4030	95	11	risk	risk	NOUN
iajs-4030	95	12	of	of	ADP
iajs-4030	95	13	ckd	ckd	PROPN
iajs-4030	95	14	in	in	ADP
iajs-4030	95	15	people	people	NOUN
iajs-4030	95	16	between	between	ADP
iajs-4030	95	17	the	the	DET
iajs-4030	95	18	ages	age	NOUN
iajs-4030	95	19	of	of	ADP
iajs-4030	95	20	40	40	NUM
iajs-4030	95	21	and	and	CCONJ
iajs-4030	95	22	65	65	NUM
iajs-4030	95	23	(	(	PUNCT
iajs-4030	95	24	26	26	NUM
iajs-4030	95	25	)	)	PUNCT
iajs-4030	95	26	.	.	PUNCT
iajs-4030	96	1	it	it	PRON
iajs-4030	96	2	's	be	AUX
iajs-4030	96	3	essential	essential	ADJ
iajs-4030	96	4	to	to	PART
iajs-4030	96	5	track	track	VERB
iajs-4030	96	6	biomarkers	biomarker	NOUN
iajs-4030	96	7	,	,	PUNCT
iajs-4030	96	8	such	such	ADJ
iajs-4030	96	9	as	as	ADP
iajs-4030	96	10	urea	urea	NOUN
iajs-4030	96	11	,	,	PUNCT
iajs-4030	96	12	while	while	SCONJ
iajs-4030	96	13	evaluating	evaluate	VERB
iajs-4030	96	14	kidney	kidney	NOUN
iajs-4030	96	15	function	function	NOUN
iajs-4030	96	16	and	and	CCONJ
iajs-4030	96	17	the	the	DET
iajs-4030	96	18	course	course	NOUN
iajs-4030	96	19	of	of	ADP
iajs-4030	96	20	ckd	ckd	PROPN
iajs-4030	96	21	.	.	PUNCT
iajs-4030	97	1	a	a	DET
iajs-4030	97	2	critical	critical	ADJ
iajs-4030	97	3	sign	sign	NOUN
iajs-4030	97	4	of	of	ADP
iajs-4030	97	5	renal	renal	ADJ
iajs-4030	97	6	failure	failure	NOUN
iajs-4030	97	7	in	in	ADP
iajs-4030	97	8	ckd	ckd	PROPN
iajs-4030	97	9	is	be	AUX
iajs-4030	97	10	elevated	elevated	ADJ
iajs-4030	97	11	urea	urea	NOUN
iajs-4030	97	12	levels	level	NOUN
iajs-4030	97	13	.	.	PUNCT
iajs-4030	98	1	for	for	SCONJ
iajs-4030	98	2	the	the	DET
iajs-4030	98	3	disease	disease	NOUN
iajs-4030	98	4	to	to	PART
iajs-4030	98	5	be	be	AUX
iajs-4030	98	6	effectively	effectively	ADV
iajs-4030	98	7	managed	manage	VERB
iajs-4030	98	8	,	,	PUNCT
iajs-4030	98	9	it	it	PRON
iajs-4030	98	10	is	be	AUX
iajs-4030	98	11	essential	essential	ADJ
iajs-4030	98	12	to	to	PART
iajs-4030	98	13	understand	understand	VERB
iajs-4030	98	14	the	the	DET
iajs-4030	98	15	mechanisms	mechanism	NOUN
iajs-4030	98	16	causing	cause	VERB
iajs-4030	98	17	urea	urea	NOUN
iajs-4030	98	18	accumulation	accumulation	NOUN
iajs-4030	98	19	and	and	CCONJ
iajs-4030	98	20	their	their	PRON
iajs-4030	98	21	associated	associated	ADJ
iajs-4030	98	22	clinical	clinical	ADJ
iajs-4030	98	23	implications	implication	NOUN
iajs-4030	98	24	(	(	PUNCT
iajs-4030	98	25	27	27	NUM
iajs-4030	98	26	)	)	PUNCT
iajs-4030	98	27	.	.	PUNCT
iajs-4030	99	1	urea	urea	PROPN
iajs-4030	99	2	is	be	AUX
iajs-4030	99	3	the	the	DET
iajs-4030	99	4	waste	waste	NOUN
iajs-4030	99	5	product	product	NOUN
iajs-4030	99	6	produced	produce	VERB
iajs-4030	99	7	by	by	ADP
iajs-4030	99	8	the	the	DET
iajs-4030	99	9	liver	liver	NOUN
iajs-4030	99	10	's	's	PART
iajs-4030	99	11	degradation	degradation	NOUN
iajs-4030	99	12	of	of	ADP
iajs-4030	99	13	proteins	protein	NOUN
iajs-4030	99	14	.	.	PUNCT
iajs-4030	100	1	urine	urine	NOUN
iajs-4030	100	2	is	be	AUX
iajs-4030	100	3	the	the	DET
iajs-4030	100	4	product	product	NOUN
iajs-4030	100	5	of	of	ADP
iajs-4030	100	6	filtration	filtration	NOUN
iajs-4030	100	7	and	and	CCONJ
iajs-4030	100	8	excretion	excretion	NOUN
iajs-4030	100	9	after	after	ADP
iajs-4030	100	10	being	be	AUX
iajs-4030	100	11	carried	carry	VERB
iajs-4030	100	12	by	by	ADP
iajs-4030	100	13	the	the	DET
iajs-4030	100	14	blood	blood	NOUN
iajs-4030	100	15	to	to	ADP
iajs-4030	100	16	the	the	DET
iajs-4030	100	17	kidneys	kidney	NOUN
iajs-4030	100	18	,	,	PUNCT
iajs-4030	100	19	and	and	CCONJ
iajs-4030	100	20	it	it	PRON
iajs-4030	100	21	is	be	AUX
iajs-4030	100	22	effectively	effectively	ADV
iajs-4030	100	23	eliminated	eliminate	VERB
iajs-4030	100	24	from	from	ADP
iajs-4030	100	25	the	the	DET
iajs-4030	100	26	blood	blood	NOUN
iajs-4030	100	27	in	in	ADP
iajs-4030	100	28	healthy	healthy	ADJ
iajs-4030	100	29	kidneys	kidney	NOUN
iajs-4030	100	30	,	,	PUNCT
iajs-4030	100	31	thereby	thereby	ADV
iajs-4030	100	32	keeping	keep	VERB
iajs-4030	100	33	serum	serum	NOUN
iajs-4030	100	34	levels	level	NOUN
iajs-4030	100	35	low	low	ADJ
iajs-4030	100	36	(	(	PUNCT
iajs-4030	100	37	28	28	NUM
iajs-4030	100	38	)	)	PUNCT
iajs-4030	100	39	.	.	PUNCT
iajs-4030	101	1	uremia	uremia	NOUN
iajs-4030	101	2	,	,	PUNCT
iajs-4030	101	3	a	a	DET
iajs-4030	101	4	condition	condition	NOUN
iajs-4030	101	5	where	where	SCONJ
iajs-4030	101	6	urea	urea	NOUN
iajs-4030	101	7	builds	build	VERB
iajs-4030	101	8	up	up	ADP
iajs-4030	101	9	in	in	ADP
iajs-4030	101	10	the	the	DET
iajs-4030	101	11	blood	blood	NOUN
iajs-4030	101	12	,	,	PUNCT
iajs-4030	101	13	is	be	AUX
iajs-4030	101	14	caused	cause	VERB
iajs-4030	101	15	by	by	ADP
iajs-4030	101	16	the	the	DET
iajs-4030	101	17	kidneys	kidney	NOUN
iajs-4030	101	18	'	'	PART
iajs-4030	101	19	diminished	diminish	VERB
iajs-4030	101	20	capacity	capacity	NOUN
iajs-4030	101	21	to	to	PART
iajs-4030	101	22	filter	filter	VERB
iajs-4030	101	23	urea	urea	NOUN
iajs-4030	101	24	in	in	ADP
iajs-4030	101	25	patients	patient	NOUN
iajs-4030	101	26	with	with	ADP
iajs-4030	101	27	ckd	ckd	PROPN
iajs-4030	101	28	.	.	PUNCT
iajs-4030	102	1	the	the	DET
iajs-4030	102	2	kidneys	kidney	NOUN
iajs-4030	102	3	excrete	excrete	VERB
iajs-4030	102	4	urea	urea	NOUN
iajs-4030	102	5	and	and	CCONJ
iajs-4030	102	6	other	other	ADJ
iajs-4030	102	7	waste	waste	NOUN
iajs-4030	102	8	products	product	NOUN
iajs-4030	102	9	less	less	ADV
iajs-4030	102	10	efficiently	efficiently	ADV
iajs-4030	102	11	as	as	SCONJ
iajs-4030	102	12	ckd	ckd	PROPN
iajs-4030	102	13	worsens	worsen	VERB
iajs-4030	102	14	due	due	ADJ
iajs-4030	102	15	to	to	ADP
iajs-4030	102	16	decreased	decrease	VERB
iajs-4030	102	17	gfr	gfr	NOUN
iajs-4030	102	18	(	(	PUNCT
iajs-4030	102	19	29	29	NUM
iajs-4030	102	20	)	)	PUNCT
iajs-4030	102	21	.	.	PUNCT
iajs-4030	103	1	a	a	DET
iajs-4030	103	2	defining	define	VERB
iajs-4030	103	3	feature	feature	NOUN
iajs-4030	103	4	of	of	ADP
iajs-4030	103	5	ckd	ckd	PROPN
iajs-4030	103	6	is	be	AUX
iajs-4030	103	7	a	a	DET
iajs-4030	103	8	decline	decline	NOUN
iajs-4030	103	9	in	in	ADP
iajs-4030	103	10	gfr	gfr	NOUN
iajs-4030	103	11	correlated	correlate	VERB
iajs-4030	103	12	with	with	ADP
iajs-4030	103	13	elevated	elevated	ADJ
iajs-4030	103	14	serum	serum	NOUN
iajs-4030	103	15	urea	urea	NOUN
iajs-4030	103	16	levels	level	NOUN
iajs-4030	103	17	.	.	PUNCT
iajs-4030	104	1	in	in	ADP
iajs-4030	104	2	addition	addition	NOUN
iajs-4030	104	3	,	,	PUNCT
iajs-4030	104	4	patients	patient	NOUN
iajs-4030	104	5	with	with	ADP
iajs-4030	104	6	ckd	ckd	PROPN
iajs-4030	104	7	may	may	AUX
iajs-4030	104	8	experience	experience	VERB
iajs-4030	104	9	worsening	worsen	VERB
iajs-4030	104	10	urea	urea	NOUN
iajs-4030	104	11	buildup	buildup	NOUN
iajs-4030	104	12	due	due	ADP
iajs-4030	104	13	to	to	ADP
iajs-4030	104	14	various	various	ADJ
iajs-4030	104	15	factors	factor	NOUN
iajs-4030	104	16	,	,	PUNCT
iajs-4030	104	17	such	such	ADJ
iajs-4030	104	18	as	as	ADP
iajs-4030	104	19	increased	increase	VERB
iajs-4030	104	20	protein	protein	NOUN
iajs-4030	104	21	catabolism	catabolism	NOUN
iajs-4030	104	22	,	,	PUNCT
iajs-4030	104	23	dehydration	dehydration	NOUN
iajs-4030	104	24	,	,	PUNCT
iajs-4030	104	25	and	and	CCONJ
iajs-4030	104	26	certain	certain	ADJ
iajs-4030	104	27	medications	medication	NOUN
iajs-4030	104	28	(	(	PUNCT
iajs-4030	104	29	30	30	NUM
iajs-4030	104	30	)	)	PUNCT
iajs-4030	104	31	.	.	PUNCT
iajs-4030	105	1	elevated	elevated	ADJ
iajs-4030	105	2	urea	urea	NOUN
iajs-4030	105	3	levels	level	NOUN
iajs-4030	105	4	have	have	VERB
iajs-4030	105	5	essential	essential	ADJ
iajs-4030	105	6	clinical	clinical	ADJ
iajs-4030	105	7	ramifications	ramification	NOUN
iajs-4030	105	8	for	for	ADP
iajs-4030	105	9	ckd	ckd	NOUN
iajs-4030	105	10	patients	patient	NOUN
iajs-4030	105	11	;	;	PUNCT
iajs-4030	105	12	ckd	ckd	NOUN
iajs-4030	105	13	patients	patient	NOUN
iajs-4030	105	14	who	who	PRON
iajs-4030	105	15	have	have	VERB
iajs-4030	105	16	elevated	elevate	VERB
iajs-4030	105	17	urea	urea	NOUN
iajs-4030	105	18	concentrations	concentration	NOUN
iajs-4030	105	19	are	be	AUX
iajs-4030	105	20	at	at	ADP
iajs-4030	105	21	markedly	markedly	ADV
iajs-4030	105	22	increased	increase	VERB
iajs-4030	105	23	risk	risk	NOUN
iajs-4030	105	24	of	of	ADP
iajs-4030	105	25	cv	cv	PROPN
iajs-4030	105	26	disease	disease	NOUN
iajs-4030	105	27	(	(	PUNCT
iajs-4030	105	28	31	31	NUM
iajs-4030	105	29	)	)	PUNCT
iajs-4030	105	30	.	.	PUNCT
iajs-4030	106	1	uremia	uremia	NOUN
iajs-4030	106	2	contributes	contribute	VERB
iajs-4030	106	3	to	to	ADP
iajs-4030	106	4	endothelial	endothelial	ADJ
iajs-4030	106	5	dysfunction	dysfunction	NOUN
iajs-4030	106	6	,	,	PUNCT
iajs-4030	106	7	inflammation	inflammation	NOUN
iajs-4030	106	8	,	,	PUNCT
iajs-4030	106	9	and	and	CCONJ
iajs-4030	106	10	arterial	arterial	ADJ
iajs-4030	106	11	stiffness	stiffness	NOUN
iajs-4030	106	12	,	,	PUNCT
iajs-4030	106	13	all	all	PRON
iajs-4030	106	14	of	of	ADP
iajs-4030	106	15	which	which	PRON
iajs-4030	106	16	increase	increase	VERB
iajs-4030	106	17	the	the	DET
iajs-4030	106	18	risk	risk	NOUN
iajs-4030	106	19	of	of	ADP
iajs-4030	106	20	cv	cv	ADJ
iajs-4030	106	21	events	event	NOUN
iajs-4030	106	22	,	,	PUNCT
iajs-4030	106	23	i.e.	i.e.	X
iajs-4030	106	24	,	,	PUNCT
iajs-4030	106	25	heart	heart	NOUN
iajs-4030	106	26	attack	attack	NOUN
iajs-4030	106	27	and	and	CCONJ
iajs-4030	106	28	stroke	stroke	NOUN
iajs-4030	106	29	(	(	PUNCT
iajs-4030	106	30	32	32	NUM
iajs-4030	106	31	)	)	PUNCT
iajs-4030	106	32	.	.	PUNCT
iajs-4030	107	1	uremic	uremic	ADJ
iajs-4030	107	2	toxins	toxin	NOUN
iajs-4030	107	3	interfere	interfere	VERB
iajs-4030	107	4	with	with	ADP
iajs-4030	107	5	protein	protein	NOUN
iajs-4030	107	6	metabolism	metabolism	NOUN
iajs-4030	107	7	and	and	CCONJ
iajs-4030	107	8	appetite	appetite	ADJ
iajs-4030	107	9	regulation	regulation	NOUN
iajs-4030	107	10	,	,	PUNCT
iajs-4030	107	11	leading	lead	VERB
iajs-4030	107	12	to	to	ADP
iajs-4030	107	13	reduced	reduce	VERB
iajs-4030	107	14	muscle	muscle	NOUN
iajs-4030	107	15	mass	mass	NOUN
iajs-4030	107	16	and	and	CCONJ
iajs-4030	107	17	strength	strength	NOUN
iajs-4030	107	18	,	,	PUNCT
iajs-4030	107	19	which	which	PRON
iajs-4030	107	20	negatively	negatively	ADV
iajs-4030	107	21	impacts	impact	VERB
iajs-4030	107	22	quality	quality	NOUN
iajs-4030	107	23	of	of	ADP
iajs-4030	107	24	life	life	NOUN
iajs-4030	107	25	and	and	CCONJ
iajs-4030	107	26	,	,	PUNCT
iajs-4030	107	27	consequently	consequently	ADV
iajs-4030	107	28	,	,	PUNCT
iajs-4030	107	29	survival	survival	NOUN
iajs-4030	107	30	(	(	PUNCT
iajs-4030	107	31	33	33	NUM
iajs-4030	107	32	)	)	PUNCT
iajs-4030	107	33	.	.	PUNCT
iajs-4030	107	34	creatinine	creatinine	NOUN
iajs-4030	107	35	,	,	PUNCT
iajs-4030	107	36	a	a	DET
iajs-4030	107	37	metabolic	metabolic	NOUN
iajs-4030	107	38	waste	waste	NOUN
iajs-4030	107	39	product	product	NOUN
iajs-4030	107	40	,	,	PUNCT
iajs-4030	107	41	is	be	AUX
iajs-4030	107	42	a	a	DET
iajs-4030	107	43	key	key	ADJ
iajs-4030	107	44	biomarker	biomarker	NOUN
iajs-4030	107	45	for	for	ADP
iajs-4030	107	46	kidney	kidney	NOUN
iajs-4030	107	47	health	health	NOUN
iajs-4030	107	48	.	.	PUNCT
iajs-4030	108	1	the	the	DET
iajs-4030	108	2	kidneys	kidney	NOUN
iajs-4030	108	3	remove	remove	VERB
iajs-4030	108	4	it	it	PRON
iajs-4030	108	5	from	from	ADP
iajs-4030	108	6	the	the	DET
iajs-4030	108	7	blood	blood	NOUN
iajs-4030	108	8	and	and	CCONJ
iajs-4030	108	9	excrete	excrete	VERB
iajs-4030	108	10	it	it	PRON
iajs-4030	108	11	as	as	ADP
iajs-4030	108	12	urine	urine	NOUN
iajs-4030	108	13	(	(	PUNCT
iajs-4030	108	14	34	34	NUM
iajs-4030	108	15	)	)	PUNCT
iajs-4030	108	16	.	.	PUNCT
iajs-4030	109	1	serum	serum	PROPN
iajs-4030	109	2	creatinine	creatinine	PROPN
iajs-4030	109	3	concentrations	concentration	NOUN
iajs-4030	109	4	are	be	AUX
iajs-4030	109	5	a	a	DET
iajs-4030	109	6	dependable	dependable	ADJ
iajs-4030	109	7	predictor	predictor	NOUN
iajs-4030	109	8	of	of	ADP
iajs-4030	109	9	the	the	DET
iajs-4030	109	10	gfr	gfr	PROPN
iajs-4030	109	11	.	.	PROPN
iajs-4030	109	12	baseline	baseline	PROPN
iajs-4030	109	13	creatinine	creatinine	PROPN
iajs-4030	109	14	levels	level	NOUN
iajs-4030	109	15	can	can	AUX
iajs-4030	109	16	be	be	AUX
iajs-4030	109	17	influenced	influence	VERB
iajs-4030	109	18	by	by	ADP
iajs-4030	109	19	several	several	ADJ
iajs-4030	109	20	factors	factor	NOUN
iajs-4030	109	21	,	,	PUNCT
iajs-4030	109	22	including	include	VERB
iajs-4030	109	23	age	age	NOUN
iajs-4030	109	24	,	,	PUNCT
iajs-4030	109	25	sex	sex	NOUN
iajs-4030	109	26	,	,	PUNCT
iajs-4030	109	27	muscle	muscle	NOUN
iajs-4030	109	28	mass	mass	NOUN
iajs-4030	109	29	,	,	PUNCT
iajs-4030	109	30	and	and	CCONJ
iajs-4030	109	31	dietary	dietary	ADJ
iajs-4030	109	32	intake	intake	NOUN
iajs-4030	109	33	;	;	PUNCT
iajs-4030	109	34	however	however	ADV
iajs-4030	109	35	,	,	PUNCT
iajs-4030	109	36	a	a	DET
iajs-4030	109	37	persistent	persistent	ADJ
iajs-4030	109	38	increase	increase	NOUN
iajs-4030	109	39	in	in	ADP
iajs-4030	109	40	creatinine	creatinine	NOUN
iajs-4030	109	41	levels	level	NOUN
iajs-4030	109	42	typically	typically	ADV
iajs-4030	109	43	indicates	indicate	VERB
iajs-4030	109	44	impaired	impaired	ADJ
iajs-4030	109	45	kidney	kidney	NOUN
iajs-4030	109	46	function	function	NOUN
iajs-4030	109	47	.	.	PUNCT
iajs-4030	110	1	serum	serum	PROPN
iajs-4030	110	2	creatinine	creatinine	PROPN
iajs-4030	110	3	levels	level	NOUN
iajs-4030	110	4	rise	rise	VERB
iajs-4030	110	5	as	as	SCONJ
iajs-4030	110	6	ckd	ckd	PROPN
iajs-4030	110	7	worsens	worsen	VERB
iajs-4030	110	8	because	because	SCONJ
iajs-4030	110	9	the	the	DET
iajs-4030	110	10	gfr	gfr	NOUN
iajs-4030	110	11	keeps	keep	VERB
iajs-4030	110	12	declining	decline	VERB
iajs-4030	110	13	,	,	PUNCT
iajs-4030	110	14	as	as	SCONJ
iajs-4030	110	15	gfr	gfr	PROPN
iajs-4030	110	16	is	be	AUX
iajs-4030	110	17	a	a	DET
iajs-4030	110	18	vital	vital	ADJ
iajs-4030	110	19	metric	metric	NOUN
iajs-4030	110	20	for	for	ADP
iajs-4030	110	21	evaluating	evaluate	VERB
iajs-4030	110	22	renal	renal	ADJ
iajs-4030	110	23	function	function	NOUN
iajs-4030	110	24	and	and	CCONJ
iajs-4030	110	25	ckd	ckd	PROPN
iajs-4030	110	26	stage	stage	NOUN
iajs-4030	110	27	(	(	PUNCT
iajs-4030	110	28	35	35	NUM
iajs-4030	110	29	)	)	PUNCT
iajs-4030	110	30	.	.	PUNCT
iajs-4030	111	1	a	a	DET
iajs-4030	111	2	healthy	healthy	ADJ
iajs-4030	111	3	kidney	kidney	NOUN
iajs-4030	111	4	's	's	PART
iajs-4030	111	5	gfr	gfr	NOUN
iajs-4030	111	6	is	be	AUX
iajs-4030	111	7	typically	typically	ADV
iajs-4030	111	8	90	90	NUM
iajs-4030	111	9	-	-	SYM
iajs-4030	111	10	120	120	NUM
iajs-4030	111	11	ml	ml	NOUN
iajs-4030	111	12	/	/	SYM
iajs-4030	111	13	min/1.73	min/1.73	NOUN
iajs-4030	111	14	m²	m²	NOUN
iajs-4030	111	15	;	;	PUNCT
iajs-4030	111	16	therefore	therefore	ADV
iajs-4030	111	17	,	,	PUNCT
iajs-4030	111	18	a	a	DET
iajs-4030	111	19	drop	drop	NOUN
iajs-4030	111	20	in	in	ADP
iajs-4030	111	21	gfr	gfr	ADJ
iajs-4030	111	22	level	level	NOUN
iajs-4030	111	23	suggests	suggest	VERB
iajs-4030	111	24	a	a	DET
iajs-4030	111	25	decline	decline	NOUN
iajs-4030	111	26	in	in	ADP
iajs-4030	111	27	renal	renal	ADJ
iajs-4030	111	28	efficiency	efficiency	NOUN
iajs-4030	111	29	and	and	CCONJ
iajs-4030	111	30	function	function	NOUN
iajs-4030	111	31	.	.	PUNCT
iajs-4030	112	1	reduced	reduce	VERB
iajs-4030	112	2	gfr	gfr	PROPN
iajs-4030	112	3	in	in	ADP
iajs-4030	112	4	ckd	ckd	PROPN
iajs-4030	112	5	is	be	AUX
iajs-4030	112	6	caused	cause	VERB
iajs-4030	112	7	by	by	ADP
iajs-4030	112	8	mechanisms	mechanism	NOUN
iajs-4030	112	9	that	that	PRON
iajs-4030	112	10	increase	increase	VERB
iajs-4030	112	11	injury	injury	NOUN
iajs-4030	112	12	to	to	ADP
iajs-4030	112	13	the	the	DET
iajs-4030	112	14	kidney	kidney	NOUN
iajs-4030	112	15	's	's	PART
iajs-4030	112	16	filtering	filter	VERB
iajs-4030	112	17	units	unit	NOUN
iajs-4030	112	18	,	,	PUNCT
iajs-4030	112	19	or	or	CCONJ
iajs-4030	112	20	nephrons	nephron	NOUN
iajs-4030	112	21	.	.	PUNCT
iajs-4030	113	1	multiple	multiple	ADJ
iajs-4030	113	2	mechanisms	mechanism	NOUN
iajs-4030	113	3	,	,	PUNCT
iajs-4030	113	4	including	include	VERB
iajs-4030	113	5	vascular	vascular	ADJ
iajs-4030	113	6	alterations	alteration	NOUN
iajs-4030	113	7	,	,	PUNCT
iajs-4030	113	8	tubulointerstitial	tubulointerstitial	ADJ
iajs-4030	113	9	injury	injury	NOUN
iajs-4030	113	10	,	,	PUNCT
iajs-4030	113	11	and	and	CCONJ
iajs-4030	113	12	glomerular	glomerular	ADJ
iajs-4030	113	13	damage	damage	NOUN
iajs-4030	113	14	,	,	PUNCT
iajs-4030	113	15	cause	cause	VERB
iajs-4030	113	16	the	the	DET
iajs-4030	113	17	decrease	decrease	NOUN
iajs-4030	113	18	in	in	ADP
iajs-4030	113	19	gfr	gfr	PROPN
iajs-4030	113	20	.	.	PUNCT
iajs-4030	114	1	anemia	anemia	PROPN
iajs-4030	114	2	,	,	PUNCT
iajs-4030	114	3	hypervolemia	hypervolemia	NOUN
iajs-4030	114	4	,	,	PUNCT
iajs-4030	114	5	and	and	CCONJ
iajs-4030	114	6	htn	htn	PROPN
iajs-4030	114	7	,	,	PUNCT
iajs-4030	114	8	in	in	ADP
iajs-4030	114	9	addition	addition	NOUN
iajs-4030	114	10	to	to	ADP
iajs-4030	114	11	low	low	ADJ
iajs-4030	114	12	levels	level	NOUN
iajs-4030	114	13	of	of	ADP
iajs-4030	114	14	serum	serum	NOUN
iajs-4030	114	15	total	total	ADJ
iajs-4030	114	16	protein	protein	NOUN
iajs-4030	114	17	and	and	CCONJ
iajs-4030	114	18	albumin	albumin	NOUN
iajs-4030	114	19	,	,	PUNCT
iajs-4030	114	20	are	be	AUX
iajs-4030	114	21	common	common	ADJ
iajs-4030	114	22	comorbidities	comorbiditie	NOUN
iajs-4030	114	23	in	in	ADP
iajs-4030	114	24	patients	patient	NOUN
iajs-4030	114	25	with	with	ADP
iajs-4030	114	26	esrd	esrd	PROPN
iajs-4030	114	27	(	(	PUNCT
iajs-4030	114	28	36	36	NUM
iajs-4030	114	29	)	)	PUNCT
iajs-4030	114	30	.	.	PUNCT
iajs-4030	115	1	primarily	primarily	ADV
iajs-4030	115	2	known	know	VERB
iajs-4030	115	3	for	for	ADP
iajs-4030	115	4	its	its	PRON
iajs-4030	115	5	role	role	NOUN
iajs-4030	115	6	in	in	ADP
iajs-4030	115	7	stabilizing	stabilize	VERB
iajs-4030	115	8	mts	mts	NOUN
iajs-4030	115	9	in	in	ADP
iajs-4030	115	10	neurons	neuron	NOUN
iajs-4030	115	11	is	be	AUX
iajs-4030	115	12	map2	map2	ADJ
iajs-4030	115	13	,	,	PUNCT
iajs-4030	115	14	which	which	PRON
iajs-4030	115	15	has	have	AUX
iajs-4030	115	16	also	also	ADV
iajs-4030	115	17	been	be	AUX
iajs-4030	115	18	implicated	implicate	VERB
iajs-4030	115	19	in	in	ADP
iajs-4030	115	20	renal	renal	ADJ
iajs-4030	115	21	pathology	pathology	NOUN
iajs-4030	115	22	.	.	PUNCT
iajs-4030	116	1	in	in	ADP
iajs-4030	116	2	ckd	ckd	PROPN
iajs-4030	116	3	,	,	PUNCT
iajs-4030	116	4	map2	map2	PROPN
iajs-4030	116	5	may	may	AUX
iajs-4030	116	6	help	help	VERB
iajs-4030	116	7	preserve	preserve	VERB
iajs-4030	116	8	the	the	DET
iajs-4030	116	9	shape	shape	NOUN
iajs-4030	116	10	of	of	ADP
iajs-4030	116	11	renal	renal	ADJ
iajs-4030	116	12	cells	cell	NOUN
iajs-4030	116	13	,	,	PUNCT
iajs-4030	116	14	especially	especially	ADV
iajs-4030	116	15	podocytes	podocyte	NOUN
iajs-4030	116	16	,	,	PUNCT
iajs-4030	116	17	which	which	PRON
iajs-4030	116	18	are	be	AUX
iajs-4030	116	19	crucial	crucial	ADJ
iajs-4030	116	20	for	for	ADP
iajs-4030	116	21	kidney	kidney	NOUN
iajs-4030	116	22	function	function	NOUN
iajs-4030	116	23	(	(	PUNCT
iajs-4030	116	24	37	37	NUM
iajs-4030	116	25	)	)	PUNCT
iajs-4030	116	26	.	.	PUNCT
iajs-4030	117	1	also	also	ADV
iajs-4030	117	2	,	,	PUNCT
iajs-4030	117	3	maps	map	NOUN
iajs-4030	117	4	are	be	AUX
iajs-4030	117	5	necessary	necessary	ADJ
iajs-4030	117	6	,	,	PUNCT
iajs-4030	117	7	under	under	ADP
iajs-4030	117	8	normal	normal	ADJ
iajs-4030	117	9	conditions	condition	NOUN
iajs-4030	117	10	,	,	PUNCT
iajs-4030	117	11	for	for	ADP
iajs-4030	117	12	preserving	preserve	VERB
iajs-4030	117	13	mt	mt	PROPN
iajs-4030	117	14	structure	structure	NOUN
iajs-4030	117	15	and	and	CCONJ
iajs-4030	117	16	function	function	NOUN
iajs-4030	117	17	.	.	PUNCT
iajs-4030	118	1	they	they	PRON
iajs-4030	118	2	have	have	VERB
iajs-4030	118	3	the	the	DET
iajs-4030	118	4	power	power	NOUN
iajs-4030	118	5	to	to	PART
iajs-4030	118	6	control	control	VERB
iajs-4030	118	7	the	the	DET
iajs-4030	118	8	interaction	interaction	NOUN
iajs-4030	118	9	between	between	ADP
iajs-4030	118	10	mts	mts	NOUN
iajs-4030	118	11	and	and	CCONJ
iajs-4030	118	12	other	other	ADJ
iajs-4030	118	13	cellular	cellular	ADJ
iajs-4030	118	14	constituents	constituent	NOUN
iajs-4030	118	15	and	and	CCONJ
iajs-4030	118	16	strengthen	strengthen	VERB
iajs-4030	118	17	microtubule	microtubule	NOUN
iajs-4030	118	18	stability	stability	NOUN
iajs-4030	118	19	and	and	CCONJ
iajs-4030	118	20	assembly	assembly	NOUN
iajs-4030	118	21	.	.	PUNCT
iajs-4030	119	1	furthermore	furthermore	ADV
iajs-4030	119	2	,	,	PUNCT
iajs-4030	119	3	maps	map	NOUN
iajs-4030	119	4	are	be	AUX
iajs-4030	119	5	made	make	VERB
iajs-4030	119	6	up	up	ADP
iajs-4030	119	7	of	of	ADP
iajs-4030	119	8	two	two	NUM
iajs-4030	119	9	functional	functional	ADJ
iajs-4030	119	10	regions	region	NOUN
iajs-4030	119	11	:	:	PUNCT
iajs-4030	119	12	an	an	DET
iajs-4030	119	13	acidic	acidic	ADJ
iajs-4030	119	14	salient	salient	NOUN
iajs-4030	119	15	binding	bind	VERB
iajs-4030	119	16	domain	domain	NOUN
iajs-4030	119	17	that	that	PRON
iajs-4030	119	18	projects	project	VERB
iajs-4030	119	19	outward	outward	ADV
iajs-4030	119	20	and	and	CCONJ
iajs-4030	119	21	forms	form	VERB
iajs-4030	119	22	a	a	DET
iajs-4030	119	23	horizontal	horizontal	ADJ
iajs-4030	119	24	bridge	bridge	NOUN
iajs-4030	119	25	connecting	connect	VERB
iajs-4030	119	26	the	the	DET
iajs-4030	119	27	map	map	NOUN
iajs-4030	119	28	to	to	ADP
iajs-4030	119	29	other	other	ADJ
iajs-4030	119	30	cell	cell	NOUN
iajs-4030	119	31	components	component	NOUN
iajs-4030	119	32	,	,	PUNCT
iajs-4030	119	33	cytoskeleton	cytoskeleton	PROPN
iajs-4030	119	34	components	component	NOUN
iajs-4030	119	35	,	,	PUNCT
iajs-4030	119	36	membranes	membrane	NOUN
iajs-4030	119	37	,	,	PUNCT
iajs-4030	119	38	and	and	CCONJ
iajs-4030	119	39	other	other	ADJ
iajs-4030	119	40	structures	structure	NOUN
iajs-4030	119	41	,	,	PUNCT
iajs-4030	119	42	and	and	CCONJ
iajs-4030	119	43	an	an	DET
iajs-4030	119	44	alkaline	alkaline	NOUN
iajs-4030	119	45	binding	bind	VERB
iajs-4030	119	46	domain	domain	NOUN
iajs-4030	119	47	that	that	PRON
iajs-4030	119	48	attaches	attach	VERB
iajs-4030	119	49	to	to	ADP
iajs-4030	119	50	the	the	DET
iajs-4030	119	51	side	side	NOUN
iajs-4030	119	52	of	of	ADP
iajs-4030	119	53	the	the	DET
iajs-4030	119	54	mt	mt	PROPN
iajs-4030	119	55	.	.	PROPN
iajs-4030	119	56	maps	map	NOUN
iajs-4030	119	57	can	can	AUX
iajs-4030	119	58	regulate	regulate	VERB
iajs-4030	119	59	the	the	DET
iajs-4030	119	60	phosphorylation	phosphorylation	NOUN
iajs-4030	119	61	and	and	CCONJ
iajs-4030	119	62	dephosphorylation	dephosphorylation	NOUN
iajs-4030	119	63	of	of	ADP
iajs-4030	119	64	specific	specific	ADJ
iajs-4030	119	65	amino	amino	ADJ
iajs-4030	119	66	acids	acid	NOUN
iajs-4030	119	67	due	due	ADP
iajs-4030	119	68	to	to	ADP
iajs-4030	119	69	their	their	PRON
iajs-4030	119	70	their	their	PRON
iajs-4030	119	71	ability	ability	NOUN
iajs-4030	119	72	to	to	PART
iajs-4030	119	73	bind	bind	VERB
iajs-4030	119	74	to	to	ADP
iajs-4030	119	75	mts	mts	NOUN
iajs-4030	119	76	(	(	PUNCT
iajs-4030	119	77	38	38	NUM
iajs-4030	119	78	)	)	PUNCT
iajs-4030	119	79	.	.	PUNCT
iajs-4030	120	1	ihjpas	ihjpas	PROPN
iajs-4030	120	2	.	.	PUNCT
iajs-4030	121	1	38(3)2025	38(3)2025	NUM
iajs-4030	121	2	279	279	NUM
iajs-4030	121	3	this	this	DET
iajs-4030	121	4	map2	map2	NOUN
iajs-4030	121	5	is	be	AUX
iajs-4030	121	6	involved	involve	VERB
iajs-4030	121	7	in	in	ADP
iajs-4030	121	8	signaling	signal	VERB
iajs-4030	121	9	pathways	pathway	NOUN
iajs-4030	121	10	affecting	affect	VERB
iajs-4030	121	11	cell	cell	NOUN
iajs-4030	121	12	survival	survival	NOUN
iajs-4030	121	13	and	and	CCONJ
iajs-4030	121	14	stress	stress	NOUN
iajs-4030	121	15	response	response	NOUN
iajs-4030	121	16	,	,	PUNCT
iajs-4030	121	17	potentially	potentially	ADV
iajs-4030	121	18	influencing	influence	VERB
iajs-4030	121	19	kidney	kidney	NOUN
iajs-4030	121	20	damage	damage	NOUN
iajs-4030	121	21	.	.	PUNCT
iajs-4030	122	1	it	it	PRON
iajs-4030	122	2	may	may	AUX
iajs-4030	122	3	contribute	contribute	VERB
iajs-4030	122	4	to	to	ADP
iajs-4030	122	5	inflammation	inflammation	NOUN
iajs-4030	122	6	and	and	CCONJ
iajs-4030	122	7	fibrosis	fibrosis	NOUN
iajs-4030	122	8	in	in	ADP
iajs-4030	122	9	ckd	ckd	PROPN
iajs-4030	122	10	,	,	PUNCT
iajs-4030	122	11	ultimately	ultimately	ADV
iajs-4030	122	12	worsening	worsen	VERB
iajs-4030	122	13	kidney	kidney	NOUN
iajs-4030	122	14	function	function	NOUN
iajs-4030	122	15	over	over	ADP
iajs-4030	122	16	time	time	NOUN
iajs-4030	122	17	.	.	PUNCT
iajs-4030	123	1	understanding	understand	VERB
iajs-4030	123	2	map2	map2	PROPN
iajs-4030	123	3	's	's	PART
iajs-4030	123	4	involvement	involvement	NOUN
iajs-4030	123	5	in	in	ADP
iajs-4030	123	6	ckd	ckd	PROPN
iajs-4030	123	7	could	could	AUX
iajs-4030	123	8	lead	lead	VERB
iajs-4030	123	9	to	to	ADP
iajs-4030	123	10	the	the	DET
iajs-4030	123	11	development	development	NOUN
iajs-4030	123	12	of	of	ADP
iajs-4030	123	13	new	new	ADJ
iajs-4030	123	14	diagnostic	diagnostic	ADJ
iajs-4030	123	15	markers	marker	NOUN
iajs-4030	123	16	and	and	CCONJ
iajs-4030	123	17	therapeutic	therapeutic	ADJ
iajs-4030	123	18	strategies	strategy	NOUN
iajs-4030	123	19	to	to	PART
iajs-4030	123	20	preserve	preserve	VERB
iajs-4030	123	21	kidney	kidney	NOUN
iajs-4030	123	22	function	function	NOUN
iajs-4030	123	23	and	and	CCONJ
iajs-4030	123	24	improve	improve	VERB
iajs-4030	123	25	patient	patient	ADJ
iajs-4030	123	26	outcomes	outcome	NOUN
iajs-4030	123	27	(	(	PUNCT
iajs-4030	123	28	39	39	NUM
iajs-4030	123	29	)	)	PUNCT
iajs-4030	123	30	.	.	PUNCT
iajs-4030	124	1	some	some	DET
iajs-4030	124	2	studies	study	NOUN
iajs-4030	124	3	indicate	indicate	VERB
iajs-4030	124	4	that	that	SCONJ
iajs-4030	124	5	podocytes	podocyte	NOUN
iajs-4030	124	6	play	play	VERB
iajs-4030	124	7	a	a	DET
iajs-4030	124	8	crucial	crucial	ADJ
iajs-4030	124	9	role	role	NOUN
iajs-4030	124	10	in	in	ADP
iajs-4030	124	11	the	the	DET
iajs-4030	124	12	gf	gf	NOUN
iajs-4030	124	13	barrier	barrier	NOUN
iajs-4030	124	14	dysfunction	dysfunction	NOUN
iajs-4030	124	15	caused	cause	VERB
iajs-4030	124	16	by	by	ADP
iajs-4030	124	17	the	the	DET
iajs-4030	124	18	hyperphosphorylation	hyperphosphorylation	NOUN
iajs-4030	124	19	of	of	ADP
iajs-4030	124	20	map2	map2	NOUN
iajs-4030	124	21	and	and	CCONJ
iajs-4030	124	22	map4	map4	NOUN
iajs-4030	124	23	.	.	PUNCT
iajs-4030	125	1	it	it	PRON
iajs-4030	125	2	is	be	AUX
iajs-4030	125	3	widely	widely	ADV
iajs-4030	125	4	acknowledged	acknowledge	VERB
iajs-4030	125	5	that	that	SCONJ
iajs-4030	125	6	the	the	DET
iajs-4030	125	7	pathogenesis	pathogenesis	NOUN
iajs-4030	125	8	of	of	ADP
iajs-4030	125	9	proteinuria	proteinuria	NOUN
iajs-4030	125	10	and	and	CCONJ
iajs-4030	125	11	glomerulosclerosis	glomerulosclerosis	NOUN
iajs-4030	125	12	is	be	AUX
iajs-4030	125	13	significantly	significantly	ADV
iajs-4030	125	14	influenced	influence	VERB
iajs-4030	125	15	by	by	ADP
iajs-4030	125	16	podocyte	podocyte	NOUN
iajs-4030	125	17	loss	loss	NOUN
iajs-4030	125	18	and	and	CCONJ
iajs-4030	125	19	dysfunction	dysfunction	NOUN
iajs-4030	125	20	(	(	PUNCT
iajs-4030	125	21	40	40	NUM
iajs-4030	125	22	)	)	PUNCT
iajs-4030	125	23	.	.	PUNCT
iajs-4030	126	1	podocytes	podocyte	NOUN
iajs-4030	126	2	are	be	AUX
iajs-4030	126	3	terminally	terminally	ADV
iajs-4030	126	4	differentiated	differentiate	VERB
iajs-4030	126	5	cells	cell	NOUN
iajs-4030	126	6	that	that	PRON
iajs-4030	126	7	line	line	VERB
iajs-4030	126	8	the	the	DET
iajs-4030	126	9	glomerular	glomerular	ADJ
iajs-4030	126	10	basement	basement	NOUN
iajs-4030	126	11	membrane	membrane	NOUN
iajs-4030	126	12	(	(	PUNCT
iajs-4030	126	13	gbm	gbm	NOUN
iajs-4030	126	14	)	)	PUNCT
iajs-4030	126	15	of	of	ADP
iajs-4030	126	16	glomerular	glomerular	ADJ
iajs-4030	126	17	capillaries	capillary	NOUN
iajs-4030	126	18	.	.	PUNCT
iajs-4030	127	1	podocytes	podocyte	NOUN
iajs-4030	127	2	,	,	PUNCT
iajs-4030	127	3	which	which	PRON
iajs-4030	127	4	utilize	utilize	VERB
iajs-4030	127	5	the	the	DET
iajs-4030	127	6	gbm	gbm	NOUN
iajs-4030	127	7	to	to	PART
iajs-4030	127	8	resist	resist	VERB
iajs-4030	127	9	outward	outward	ADJ
iajs-4030	127	10	expansion	expansion	NOUN
iajs-4030	127	11	and	and	CCONJ
iajs-4030	127	12	maintain	maintain	VERB
iajs-4030	127	13	glomerular	glomerular	ADJ
iajs-4030	127	14	structural	structural	ADJ
iajs-4030	127	15	integrity	integrity	NOUN
iajs-4030	127	16	,	,	PUNCT
iajs-4030	127	17	primarily	primarily	ADV
iajs-4030	127	18	function	function	VERB
iajs-4030	127	19	through	through	ADP
iajs-4030	127	20	their	their	PRON
iajs-4030	127	21	foot	foot	NOUN
iajs-4030	127	22	processes	process	NOUN
iajs-4030	127	23	(	(	PUNCT
iajs-4030	127	24	41	41	NUM
iajs-4030	127	25	)	)	PUNCT
iajs-4030	127	26	.	.	PUNCT
iajs-4030	128	1	podocytes	podocyte	NOUN
iajs-4030	128	2	subjected	subject	VERB
iajs-4030	128	3	to	to	ADP
iajs-4030	128	4	pathological	pathological	ADJ
iajs-4030	128	5	stressors	stressor	NOUN
iajs-4030	128	6	undergo	undergo	VERB
iajs-4030	128	7	a	a	DET
iajs-4030	128	8	range	range	NOUN
iajs-4030	128	9	of	of	ADP
iajs-4030	128	10	alterations	alteration	NOUN
iajs-4030	128	11	,	,	PUNCT
iajs-4030	128	12	including	include	VERB
iajs-4030	128	13	dissociation	dissociation	NOUN
iajs-4030	128	14	,	,	PUNCT
iajs-4030	128	15	apoptosis	apoptosis	NOUN
iajs-4030	128	16	,	,	PUNCT
iajs-4030	128	17	hypertrophy	hypertrophy	NOUN
iajs-4030	128	18	,	,	PUNCT
iajs-4030	128	19	and	and	CCONJ
iajs-4030	128	20	emt	emt	PROPN
iajs-4030	128	21	,	,	PUNCT
iajs-4030	128	22	depending	depend	VERB
iajs-4030	128	23	on	on	ADP
iajs-4030	128	24	the	the	DET
iajs-4030	128	25	extent	extent	NOUN
iajs-4030	128	26	of	of	ADP
iajs-4030	128	27	the	the	DET
iajs-4030	128	28	injury	injury	NOUN
iajs-4030	128	29	(	(	PUNCT
iajs-4030	128	30	42	42	NUM
iajs-4030	128	31	)	)	PUNCT
iajs-4030	128	32	.	.	PUNCT
iajs-4030	129	1	due	due	ADP
iajs-4030	129	2	to	to	ADP
iajs-4030	129	3	their	their	PRON
iajs-4030	129	4	limited	limited	ADJ
iajs-4030	129	5	developmental	developmental	ADJ
iajs-4030	129	6	capability	capability	NOUN
iajs-4030	129	7	,	,	PUNCT
iajs-4030	129	8	podocyte	podocyte	NOUN
iajs-4030	129	9	detachment	detachment	NOUN
iajs-4030	129	10	from	from	ADP
iajs-4030	129	11	the	the	DET
iajs-4030	129	12	gbm	gbm	NOUN
iajs-4030	129	13	and	and	CCONJ
iajs-4030	129	14	apoptosis	apoptosis	NOUN
iajs-4030	129	15	will	will	AUX
iajs-4030	129	16	inevitably	inevitably	ADV
iajs-4030	129	17	lead	lead	VERB
iajs-4030	129	18	to	to	ADP
iajs-4030	129	19	cell	cell	NOUN
iajs-4030	129	20	loss	loss	NOUN
iajs-4030	129	21	or	or	CCONJ
iajs-4030	129	22	dropout	dropout	NOUN
iajs-4030	129	23	.	.	PUNCT
iajs-4030	130	1	this	this	PRON
iajs-4030	130	2	will	will	AUX
iajs-4030	130	3	decrease	decrease	VERB
iajs-4030	130	4	podocyte	podocyte	NOUN
iajs-4030	130	5	density	density	NOUN
iajs-4030	130	6	,	,	PUNCT
iajs-4030	130	7	ultimately	ultimately	ADV
iajs-4030	130	8	compromising	compromise	VERB
iajs-4030	130	9	gf	gf	NOUN
iajs-4030	130	10	and	and	CCONJ
iajs-4030	130	11	leading	lead	VERB
iajs-4030	130	12	to	to	ADP
iajs-4030	130	13	proteinuria	proteinuria	NOUN
iajs-4030	130	14	.	.	PUNCT
iajs-4030	131	1	investigational	investigational	ADJ
iajs-4030	131	2	evidence	evidence	NOUN
iajs-4030	131	3	indicates	indicate	VERB
iajs-4030	131	4	that	that	SCONJ
iajs-4030	131	5	in	in	ADP
iajs-4030	131	6	the	the	DET
iajs-4030	131	7	late	late	ADJ
iajs-4030	131	8	phase	phase	NOUN
iajs-4030	131	9	of	of	ADP
iajs-4030	131	10	ckd	ckd	PROPN
iajs-4030	131	11	,	,	PUNCT
iajs-4030	131	12	when	when	SCONJ
iajs-4030	131	13	proteinuria	proteinuria	PROPN
iajs-4030	131	14	is	be	AUX
iajs-4030	131	15	already	already	ADV
iajs-4030	131	16	evident	evident	ADJ
iajs-4030	131	17	,	,	PUNCT
iajs-4030	131	18	podocyte	podocyte	NOUN
iajs-4030	131	19	defeat	defeat	NOUN
iajs-4030	131	20	occurs	occur	VERB
iajs-4030	131	21	.	.	PUNCT
iajs-4030	132	1	thus	thus	ADV
iajs-4030	132	2	,	,	PUNCT
iajs-4030	132	3	rather	rather	ADV
iajs-4030	132	4	than	than	ADP
iajs-4030	132	5	podocyte	podocyte	NOUN
iajs-4030	132	6	loss	loss	NOUN
iajs-4030	132	7	,	,	PUNCT
iajs-4030	132	8	it	it	PRON
iajs-4030	132	9	is	be	AUX
iajs-4030	132	10	more	more	ADV
iajs-4030	132	11	likely	likely	ADJ
iajs-4030	132	12	that	that	SCONJ
iajs-4030	132	13	irregular	irregular	ADJ
iajs-4030	132	14	changes	change	NOUN
iajs-4030	132	15	in	in	ADP
iajs-4030	132	16	podocyte	podocyte	NOUN
iajs-4030	132	17	function	function	NOUN
iajs-4030	132	18	or	or	CCONJ
iajs-4030	132	19	differentiation	differentiation	NOUN
iajs-4030	132	20	are	be	AUX
iajs-4030	132	21	widespread	widespread	ADJ
iajs-4030	132	22	,	,	PUNCT
iajs-4030	132	23	and	and	CCONJ
iajs-4030	132	24	proteinuria	proteinuria	PROPN
iajs-4030	132	25	tends	tend	VERB
iajs-4030	132	26	to	to	PART
iajs-4030	132	27	present	present	VERB
iajs-4030	132	28	with	with	ADP
iajs-4030	132	29	a	a	DET
iajs-4030	132	30	wide	wide	ADJ
iajs-4030	132	31	range	range	NOUN
iajs-4030	132	32	of	of	ADP
iajs-4030	132	33	clinical	clinical	ADJ
iajs-4030	132	34	conditions	condition	NOUN
iajs-4030	132	35	.	.	PUNCT
iajs-4030	133	1	podocytes	podocyte	NOUN
iajs-4030	133	2	lose	lose	VERB
iajs-4030	133	3	common	common	ADJ
iajs-4030	133	4	mesenchymal	mesenchymal	ADJ
iajs-4030	133	5	markers	marker	NOUN
iajs-4030	133	6	such	such	ADJ
iajs-4030	133	7	as	as	ADP
iajs-4030	133	8	collagen	collagen	NOUN
iajs-4030	133	9	i	i	PRON
iajs-4030	133	10	and	and	CCONJ
iajs-4030	133	11	fibronectin	fibronectin	NOUN
iajs-4030	133	12	.	.	PUNCT
iajs-4030	134	1	they	they	PRON
iajs-4030	134	2	also	also	ADV
iajs-4030	134	3	acquire	acquire	VERB
iajs-4030	134	4	epithelial	epithelial	ADJ
iajs-4030	134	5	markers	marker	NOUN
iajs-4030	134	6	,	,	PUNCT
iajs-4030	134	7	such	such	ADJ
iajs-4030	134	8	as	as	ADP
iajs-4030	134	9	p	p	NOUN
iajs-4030	134	10	-	-	PUNCT
iajs-4030	134	11	cadherin	cadherin	NOUN
iajs-4030	134	12	and	and	CCONJ
iajs-4030	134	13	nephrin	nephrin	NOUN
iajs-4030	134	14	,	,	PUNCT
iajs-4030	134	15	de	de	X
iajs-4030	134	16	novo	novo	NOUN
iajs-4030	134	17	as	as	SCONJ
iajs-4030	134	18	they	they	PRON
iajs-4030	134	19	undergo	undergo	VERB
iajs-4030	134	20	the	the	DET
iajs-4030	134	21	epithelialmesenchymal	epithelialmesenchymal	ADJ
iajs-4030	134	22	transition	transition	NOUN
iajs-4030	134	23	(	(	PUNCT
iajs-4030	134	24	emt	emt	PROPN
iajs-4030	134	25	)	)	PUNCT
iajs-4030	134	26	(	(	PUNCT
iajs-4030	134	27	43	43	NUM
iajs-4030	134	28	)	)	PUNCT
iajs-4030	134	29	.	.	PUNCT
iajs-4030	135	1	nephrin	nephrin	PROPN
iajs-4030	135	2	is	be	AUX
iajs-4030	135	3	an	an	DET
iajs-4030	135	4	essential	essential	ADJ
iajs-4030	135	5	component	component	NOUN
iajs-4030	135	6	of	of	ADP
iajs-4030	135	7	the	the	DET
iajs-4030	135	8	slit	slit	ADJ
iajs-4030	135	9	diaphragm	diaphragm	NOUN
iajs-4030	135	10	cell	cell	NOUN
iajs-4030	135	11	adhesion	adhesion	NOUN
iajs-4030	135	12	complexes	complex	NOUN
iajs-4030	135	13	,	,	PUNCT
iajs-4030	135	14	and	and	CCONJ
iajs-4030	135	15	its	its	PRON
iajs-4030	135	16	absence	absence	NOUN
iajs-4030	135	17	causes	cause	VERB
iajs-4030	135	18	the	the	DET
iajs-4030	135	19	slit	slit	ADJ
iajs-4030	135	20	diaphragm	diaphragm	NOUN
iajs-4030	135	21	to	to	PART
iajs-4030	135	22	become	become	VERB
iajs-4030	135	23	less	less	ADV
iajs-4030	135	24	cohesive	cohesive	ADJ
iajs-4030	135	25	,	,	PUNCT
iajs-4030	135	26	facilitating	facilitate	VERB
iajs-4030	135	27	the	the	DET
iajs-4030	135	28	separation	separation	NOUN
iajs-4030	135	29	of	of	ADP
iajs-4030	135	30	podocytes	podocyte	NOUN
iajs-4030	135	31	from	from	ADP
iajs-4030	135	32	the	the	DET
iajs-4030	135	33	gbm	gbm	NOUN
iajs-4030	135	34	(	(	PUNCT
iajs-4030	135	35	44	44	NUM
iajs-4030	135	36	)	)	PUNCT
iajs-4030	135	37	.	.	PUNCT
iajs-4030	136	1	it	it	PRON
iajs-4030	136	2	has	have	AUX
iajs-4030	136	3	been	be	AUX
iajs-4030	136	4	associated	associate	VERB
iajs-4030	136	5	with	with	ADP
iajs-4030	136	6	hypoxia	hypoxia	NOUN
iajs-4030	136	7	,	,	PUNCT
iajs-4030	136	8	reactive	reactive	ADJ
iajs-4030	136	9	oxygen	oxygen	NOUN
iajs-4030	136	10	species	specie	NOUN
iajs-4030	136	11	,	,	PUNCT
iajs-4030	136	12	growth	growth	NOUN
iajs-4030	136	13	factors	factor	NOUN
iajs-4030	136	14	,	,	PUNCT
iajs-4030	136	15	pro	pro	ADJ
iajs-4030	136	16	-	-	ADJ
iajs-4030	136	17	fibrotic	fibrotic	ADJ
iajs-4030	136	18	cytokines	cytokine	NOUN
iajs-4030	136	19	,	,	PUNCT
iajs-4030	136	20	advanced	advanced	ADJ
iajs-4030	136	21	glycation	glycation	NOUN
iajs-4030	136	22	end	end	NOUN
iajs-4030	136	23	products	product	NOUN
iajs-4030	136	24	,	,	PUNCT
iajs-4030	136	25	and	and	CCONJ
iajs-4030	136	26	metalloproteinases	metalloproteinase	NOUN
iajs-4030	136	27	(	(	PUNCT
iajs-4030	136	28	45	45	NUM
iajs-4030	136	29	)	)	PUNCT
iajs-4030	136	30	.	.	PUNCT
iajs-4030	137	1	podocytes	podocyte	NOUN
iajs-4030	137	2	vary	vary	VERB
iajs-4030	137	3	from	from	ADP
iajs-4030	137	4	other	other	ADJ
iajs-4030	137	5	renal	renal	ADJ
iajs-4030	137	6	cells	cell	NOUN
iajs-4030	137	7	in	in	ADP
iajs-4030	137	8	that	that	SCONJ
iajs-4030	137	9	they	they	PRON
iajs-4030	137	10	undergo	undergo	VERB
iajs-4030	137	11	severe	severe	ADJ
iajs-4030	137	12	emt	emt	NOUN
iajs-4030	137	13	and	and	CCONJ
iajs-4030	137	14	die	die	VERB
iajs-4030	137	15	in	in	ADP
iajs-4030	137	16	response	response	NOUN
iajs-4030	137	17	to	to	ADP
iajs-4030	137	18	injury	injury	NOUN
iajs-4030	137	19	or	or	CCONJ
iajs-4030	137	20	unpleasant	unpleasant	ADJ
iajs-4030	137	21	stimuli	stimulus	NOUN
iajs-4030	137	22	,	,	PUNCT
iajs-4030	137	23	making	make	VERB
iajs-4030	137	24	them	they	PRON
iajs-4030	137	25	terminally	terminally	ADV
iajs-4030	137	26	differentiated	differentiate	VERB
iajs-4030	137	27	and	and	CCONJ
iajs-4030	137	28	incapable	incapable	ADJ
iajs-4030	137	29	of	of	ADP
iajs-4030	137	30	reproducing	reproduce	VERB
iajs-4030	137	31	.	.	PUNCT
iajs-4030	138	1	this	this	DET
iajs-4030	138	2	study	study	NOUN
iajs-4030	138	3	's	's	PART
iajs-4030	138	4	intriguing	intriguing	ADJ
iajs-4030	138	5	conclusion	conclusion	NOUN
iajs-4030	138	6	comes	come	VERB
iajs-4030	138	7	from	from	ADP
iajs-4030	138	8	it	it	PRON
iajs-4030	138	9	.	.	PUNCT
iajs-4030	139	1	consequently	consequently	ADV
iajs-4030	139	2	,	,	PUNCT
iajs-4030	139	3	endothelial	endothelial	ADJ
iajs-4030	139	4	cells	cell	NOUN
iajs-4030	139	5	undergo	undergo	VERB
iajs-4030	139	6	an	an	DET
iajs-4030	139	7	emt	emt	NOUN
iajs-4030	139	8	,	,	PUNCT
iajs-4030	139	9	which	which	PRON
iajs-4030	139	10	leads	lead	VERB
iajs-4030	139	11	to	to	ADP
iajs-4030	139	12	an	an	DET
iajs-4030	139	13	increase	increase	NOUN
iajs-4030	139	14	in	in	ADP
iajs-4030	139	15	mesenchymal	mesenchymal	ADJ
iajs-4030	139	16	cells	cell	NOUN
iajs-4030	139	17	.	.	PUNCT
iajs-4030	140	1	moreover	moreover	ADV
iajs-4030	140	2	,	,	PUNCT
iajs-4030	140	3	proteinuria	proteinuria	PROPN
iajs-4030	140	4	may	may	AUX
iajs-4030	140	5	be	be	AUX
iajs-4030	140	6	connected	connect	VERB
iajs-4030	140	7	to	to	ADP
iajs-4030	140	8	either	either	CCONJ
iajs-4030	140	9	podocyte	podocyte	NOUN
iajs-4030	140	10	emt	emt	NOUN
iajs-4030	140	11	or	or	CCONJ
iajs-4030	140	12	overt	overt	ADJ
iajs-4030	140	13	death	death	NOUN
iajs-4030	140	14	.	.	PUNCT
iajs-4030	141	1	to	to	PART
iajs-4030	141	2	accomplish	accomplish	VERB
iajs-4030	141	3	emt	emt	PROPN
iajs-4030	141	4	,	,	PUNCT
iajs-4030	141	5	map2	map2	PROPN
iajs-4030	141	6	has	have	VERB
iajs-4030	141	7	to	to	PART
iajs-4030	141	8	rearrange	rearrange	VERB
iajs-4030	141	9	the	the	DET
iajs-4030	141	10	cytoskeleton	cytoskeleton	NOUN
iajs-4030	141	11	,	,	PUNCT
iajs-4030	141	12	and	and	CCONJ
iajs-4030	141	13	this	this	PRON
iajs-4030	141	14	is	be	AUX
iajs-4030	141	15	the	the	DET
iajs-4030	141	16	default	default	NOUN
iajs-4030	141	17	result	result	NOUN
iajs-4030	141	18	of	of	ADP
iajs-4030	141	19	emt	emt	PROPN
iajs-4030	141	20	triggering	triggering	NOUN
iajs-4030	141	21	,	,	PUNCT
iajs-4030	141	22	also	also	ADV
iajs-4030	141	23	serving	serve	VERB
iajs-4030	141	24	as	as	ADP
iajs-4030	141	25	a	a	DET
iajs-4030	141	26	switch	switch	NOUN
iajs-4030	141	27	in	in	ADP
iajs-4030	141	28	this	this	DET
iajs-4030	141	29	study	study	NOUN
iajs-4030	141	30	(	(	PUNCT
iajs-4030	141	31	46	46	NUM
iajs-4030	141	32	)	)	PUNCT
iajs-4030	141	33	.	.	PUNCT
iajs-4030	142	1	an	an	DET
iajs-4030	142	2	evidence	evidence	NOUN
iajs-4030	142	3	study	study	NOUN
iajs-4030	142	4	revealed	reveal	VERB
iajs-4030	142	5	that	that	SCONJ
iajs-4030	142	6	actin	actin	NOUN
iajs-4030	142	7	restructuring	restructuring	NOUN
iajs-4030	142	8	is	be	AUX
iajs-4030	142	9	closely	closely	ADV
iajs-4030	142	10	associated	associate	VERB
iajs-4030	142	11	with	with	ADP
iajs-4030	142	12	the	the	DET
iajs-4030	142	13	elimination	elimination	NOUN
iajs-4030	142	14	of	of	ADP
iajs-4030	142	15	the	the	DET
iajs-4030	142	16	foot	foot	NOUN
iajs-4030	142	17	process	process	NOUN
iajs-4030	142	18	,	,	PUNCT
iajs-4030	142	19	which	which	PRON
iajs-4030	142	20	is	be	AUX
iajs-4030	142	21	linked	link	VERB
iajs-4030	142	22	to	to	ADP
iajs-4030	142	23	proteinuria	proteinuria	NOUN
iajs-4030	142	24	.	.	PUNCT
iajs-4030	143	1	further	further	ADJ
iajs-4030	143	2	research	research	NOUN
iajs-4030	143	3	is	be	AUX
iajs-4030	143	4	necessary	necessary	ADJ
iajs-4030	143	5	to	to	PART
iajs-4030	143	6	determine	determine	VERB
iajs-4030	143	7	the	the	DET
iajs-4030	143	8	precise	precise	ADJ
iajs-4030	143	9	mechanism	mechanism	NOUN
iajs-4030	143	10	controlling	control	VERB
iajs-4030	143	11	cytoskeletal	cytoskeletal	ADJ
iajs-4030	143	12	rearrangement	rearrangement	NOUN
iajs-4030	143	13	during	during	ADP
iajs-4030	143	14	meniscal	meniscal	ADJ
iajs-4030	143	15	cell	cell	NOUN
iajs-4030	143	16	emt	emt	PROPN
iajs-4030	143	17	,	,	PUNCT
iajs-4030	143	18	as	as	SCONJ
iajs-4030	143	19	it	it	PRON
iajs-4030	143	20	is	be	AUX
iajs-4030	143	21	currently	currently	ADV
iajs-4030	143	22	unknown	unknown	ADJ
iajs-4030	143	23	.	.	PUNCT
iajs-4030	144	1	actin	actin	NOUN
iajs-4030	144	2	-	-	PUNCT
iajs-4030	144	3	mt	mt	PROPN
iajs-4030	144	4	interactions	interaction	NOUN
iajs-4030	144	5	are	be	AUX
iajs-4030	144	6	a	a	DET
iajs-4030	144	7	phenomenon	phenomenon	NOUN
iajs-4030	144	8	that	that	PRON
iajs-4030	144	9	controls	control	VERB
iajs-4030	144	10	several	several	ADJ
iajs-4030	144	11	essential	essential	ADJ
iajs-4030	144	12	cellular	cellular	ADJ
iajs-4030	144	13	functions	function	NOUN
iajs-4030	144	14	,	,	PUNCT
iajs-4030	144	15	including	include	VERB
iajs-4030	144	16	cell	cell	NOUN
iajs-4030	144	17	division	division	NOUN
iajs-4030	144	18	and	and	CCONJ
iajs-4030	144	19	motility	motility	NOUN
iajs-4030	144	20	.	.	PUNCT
iajs-4030	145	1	it	it	PRON
iajs-4030	145	2	has	have	AUX
iajs-4030	145	3	been	be	AUX
iajs-4030	145	4	demonstrated	demonstrate	VERB
iajs-4030	145	5	that	that	SCONJ
iajs-4030	145	6	maps	map	NOUN
iajs-4030	145	7	play	play	VERB
iajs-4030	145	8	a	a	DET
iajs-4030	145	9	crucial	crucial	ADJ
iajs-4030	145	10	role	role	NOUN
iajs-4030	145	11	in	in	ADP
iajs-4030	145	12	regulating	regulate	VERB
iajs-4030	145	13	mt	mt	PROPN
iajs-4030	145	14	and	and	CCONJ
iajs-4030	145	15	actin	actin	NOUN
iajs-4030	145	16	connections	connection	NOUN
iajs-4030	145	17	during	during	ADP
iajs-4030	145	18	the	the	DET
iajs-4030	145	19	development	development	NOUN
iajs-4030	145	20	of	of	ADP
iajs-4030	145	21	cytoskeletal	cytoskeletal	ADJ
iajs-4030	145	22	networks	network	NOUN
iajs-4030	145	23	(	(	PUNCT
iajs-4030	145	24	47	47	NUM
iajs-4030	145	25	)	)	PUNCT
iajs-4030	145	26	.	.	PUNCT
iajs-4030	146	1	hyperphosphorylated	hyperphosphorylated	ADJ
iajs-4030	146	2	map4	map4	NOUN
iajs-4030	146	3	exhibited	exhibit	VERB
iajs-4030	146	4	signs	sign	NOUN
iajs-4030	146	5	of	of	ADP
iajs-4030	146	6	pathological	pathological	ADJ
iajs-4030	146	7	alterations	alteration	NOUN
iajs-4030	146	8	in	in	ADP
iajs-4030	146	9	dn	dn	PROPN
iajs-4030	146	10	,	,	PUNCT
iajs-4030	146	11	including	include	VERB
iajs-4030	146	12	proteinuria	proteinuria	NOUN
iajs-4030	146	13	,	,	PUNCT
iajs-4030	146	14	senescence	senescence	NOUN
iajs-4030	146	15	,	,	PUNCT
iajs-4030	146	16	and	and	CCONJ
iajs-4030	146	17	significant	significant	ADJ
iajs-4030	146	18	emt	emt	NOUN
iajs-4030	146	19	of	of	ADP
iajs-4030	146	20	meniscal	meniscal	ADJ
iajs-4030	146	21	cells	cell	NOUN
iajs-4030	146	22	(	(	PUNCT
iajs-4030	146	23	48	48	NUM
iajs-4030	146	24	)	)	PUNCT
iajs-4030	146	25	.	.	PUNCT
iajs-4030	147	1	furthermore	furthermore	ADV
iajs-4030	147	2	,	,	PUNCT
iajs-4030	147	3	in	in	ADP
iajs-4030	147	4	map4	map4	NOUN
iajs-4030	147	5	models	model	NOUN
iajs-4030	147	6	,	,	PUNCT
iajs-4030	147	7	hyperglycemia	hyperglycemia	NOUN
iajs-4030	147	8	made	make	VERB
iajs-4030	147	9	these	these	DET
iajs-4030	147	10	degenerative	degenerative	ADJ
iajs-4030	147	11	alterations	alteration	NOUN
iajs-4030	147	12	in	in	ADP
iajs-4030	147	13	the	the	DET
iajs-4030	147	14	kidneys	kidney	NOUN
iajs-4030	147	15	worse	bad	ADJ
iajs-4030	147	16	.	.	PUNCT
iajs-4030	148	1	as	as	ADP
iajs-4030	148	2	a	a	DET
iajs-4030	148	3	result	result	NOUN
iajs-4030	148	4	,	,	PUNCT
iajs-4030	148	5	the	the	DET
iajs-4030	148	6	cumulative	cumulative	ADJ
iajs-4030	148	7	damage	damage	NOUN
iajs-4030	148	8	caused	cause	VERB
iajs-4030	148	9	by	by	ADP
iajs-4030	148	10	either	either	CCONJ
iajs-4030	148	11	high	high	ADJ
iajs-4030	148	12	blood	blood	NOUN
iajs-4030	148	13	glucose	glucose	NOUN
iajs-4030	148	14	or	or	CCONJ
iajs-4030	148	15	map4	map4	NOUN
iajs-4030	148	16	hyperphosphorylation	hyperphosphorylation	NOUN
iajs-4030	148	17	worsens	worsen	VERB
iajs-4030	148	18	aging	aging	NOUN
iajs-4030	148	19	and	and	CCONJ
iajs-4030	148	20	nephropathy	nephropathy	NOUN
iajs-4030	148	21	over	over	ADP
iajs-4030	148	22	time	time	NOUN
iajs-4030	148	23	.	.	PUNCT
iajs-4030	149	1	although	although	SCONJ
iajs-4030	149	2	age	age	NOUN
iajs-4030	149	3	is	be	AUX
iajs-4030	149	4	not	not	PART
iajs-4030	149	5	the	the	DET
iajs-4030	149	6	primary	primary	ADJ
iajs-4030	149	7	factor	factor	NOUN
iajs-4030	149	8	,	,	PUNCT
iajs-4030	149	9	aged	aged	ADJ
iajs-4030	149	10	organs	organ	NOUN
iajs-4030	149	11	and	and	CCONJ
iajs-4030	149	12	cells	cell	NOUN
iajs-4030	149	13	can	can	AUX
iajs-4030	149	14	not	not	PART
iajs-4030	149	15	compensate	compensate	VERB
iajs-4030	149	16	for	for	ADP
iajs-4030	149	17	their	their	PRON
iajs-4030	149	18	decline	decline	NOUN
iajs-4030	149	19	.	.	PUNCT
iajs-4030	150	1	the	the	DET
iajs-4030	150	2	p38/	p38/	PROPN
iajs-4030	150	3	ihjpas	ihjpas	PROPN
iajs-4030	150	4	.	.	PUNCT
iajs-4030	151	1	38(3)2025	38(3)2025	NUM
iajs-4030	151	2	280	280	NUM
iajs-4030	151	3	mitogen	mitogen	NOUN
iajs-4030	151	4	-	-	PUNCT
iajs-4030	151	5	activated	activate	VERB
iajs-4030	151	6	protein	protein	NOUN
iajs-4030	151	7	kinases	kinase	NOUN
iajs-4030	151	8	(	(	PUNCT
iajs-4030	151	9	mapks	mapks	NOUN
iajs-4030	151	10	)	)	PUNCT
iajs-4030	151	11	have	have	AUX
iajs-4030	151	12	been	be	AUX
iajs-4030	151	13	identified	identify	VERB
iajs-4030	151	14	as	as	ADP
iajs-4030	151	15	a	a	DET
iajs-4030	151	16	key	key	ADJ
iajs-4030	151	17	modulator	modulator	NOUN
iajs-4030	151	18	of	of	ADP
iajs-4030	151	19	inflammatory	inflammatory	ADJ
iajs-4030	151	20	responses	response	NOUN
iajs-4030	151	21	and	and	CCONJ
iajs-4030	151	22	mitochondrial	mitochondrial	ADJ
iajs-4030	151	23	dysfunction	dysfunction	NOUN
iajs-4030	151	24	in	in	ADP
iajs-4030	151	25	diabetes	diabetes	NOUN
iajs-4030	151	26	,	,	PUNCT
iajs-4030	151	27	as	as	ADV
iajs-4030	151	28	well	well	ADV
iajs-4030	151	29	as	as	ADP
iajs-4030	151	30	other	other	ADJ
iajs-4030	151	31	aspects	aspect	NOUN
iajs-4030	151	32	related	relate	VERB
iajs-4030	151	33	to	to	ADP
iajs-4030	151	34	the	the	DET
iajs-4030	151	35	pathophysiology	pathophysiology	NOUN
iajs-4030	151	36	of	of	ADP
iajs-4030	151	37	dn	dn	PROPN
iajs-4030	151	38	(	(	PUNCT
iajs-4030	151	39	49	49	NUM
iajs-4030	151	40	)	)	PUNCT
iajs-4030	151	41	.	.	PUNCT
iajs-4030	152	1	renal	renal	ADJ
iajs-4030	152	2	proximal	proximal	ADJ
iajs-4030	152	3	tubule	tubule	NOUN
iajs-4030	152	4	epithelial	epithelial	ADJ
iajs-4030	152	5	cells	cell	NOUN
iajs-4030	152	6	have	have	AUX
iajs-4030	152	7	been	be	AUX
iajs-4030	152	8	shown	show	VERB
iajs-4030	152	9	to	to	PART
iajs-4030	152	10	contain	contain	VERB
iajs-4030	152	11	p38/	p38/	NOUN
iajs-4030	152	12	mapks	mapks	NOUN
iajs-4030	152	13	,	,	PUNCT
iajs-4030	152	14	which	which	PRON
iajs-4030	152	15	have	have	AUX
iajs-4030	152	16	been	be	AUX
iajs-4030	152	17	linked	link	VERB
iajs-4030	152	18	to	to	ADP
iajs-4030	152	19	emt	emt	PROPN
iajs-4030	152	20	(	(	PUNCT
iajs-4030	152	21	50	50	NUM
iajs-4030	152	22	)	)	PUNCT
iajs-4030	152	23	.	.	PUNCT
iajs-4030	153	1	5	5	X
iajs-4030	153	2	.	.	X
iajs-4030	153	3	conclusion	conclusion	NOUN
iajs-4030	153	4	patients	patient	NOUN
iajs-4030	153	5	with	with	ADP
iajs-4030	153	6	ckd	ckd	PROPN
iajs-4030	153	7	had	have	AUX
iajs-4030	153	8	increased	increase	VERB
iajs-4030	153	9	serum	serum	NOUN
iajs-4030	153	10	map2	map2	PROPN
iajs-4030	153	11	levels	level	NOUN
iajs-4030	153	12	,	,	PUNCT
iajs-4030	153	13	indicating	indicate	VERB
iajs-4030	153	14	its	its	PRON
iajs-4030	153	15	vital	vital	ADJ
iajs-4030	153	16	role	role	NOUN
iajs-4030	153	17	in	in	ADP
iajs-4030	153	18	renal	renal	ADJ
iajs-4030	153	19	failure	failure	NOUN
iajs-4030	153	20	.	.	PUNCT
iajs-4030	154	1	map2	map2	PROPN
iajs-4030	154	2	may	may	AUX
iajs-4030	154	3	,	,	PUNCT
iajs-4030	154	4	therefore	therefore	ADV
iajs-4030	154	5	,	,	PUNCT
iajs-4030	154	6	be	be	AUX
iajs-4030	154	7	regarded	regard	VERB
iajs-4030	154	8	as	as	ADP
iajs-4030	154	9	a	a	DET
iajs-4030	154	10	biomarker	biomarker	NOUN
iajs-4030	154	11	of	of	ADP
iajs-4030	154	12	the	the	DET
iajs-4030	154	13	development	development	NOUN
iajs-4030	154	14	of	of	ADP
iajs-4030	154	15	renal	renal	ADJ
iajs-4030	154	16	injury	injury	NOUN
iajs-4030	154	17	in	in	ADP
iajs-4030	154	18	ckd	ckd	PROPN
iajs-4030	154	19	patients	patient	NOUN
iajs-4030	154	20	.	.	PUNCT
iajs-4030	155	1	hypoxia	hypoxia	NOUN
iajs-4030	155	2	and	and	CCONJ
iajs-4030	155	3	oxidative	oxidative	ADJ
iajs-4030	155	4	stress	stress	NOUN
iajs-4030	155	5	may	may	AUX
iajs-4030	155	6	contribute	contribute	VERB
iajs-4030	155	7	to	to	ADP
iajs-4030	155	8	this	this	PRON
iajs-4030	155	9	,	,	PUNCT
iajs-4030	155	10	as	as	SCONJ
iajs-4030	155	11	they	they	PRON
iajs-4030	155	12	can	can	AUX
iajs-4030	155	13	work	work	VERB
iajs-4030	155	14	in	in	ADP
iajs-4030	155	15	tandem	tandem	NOUN
iajs-4030	155	16	with	with	ADP
iajs-4030	155	17	increased	increase	VERB
iajs-4030	155	18	albuminuria	albuminuria	NOUN
iajs-4030	155	19	and	and	CCONJ
iajs-4030	155	20	decreased	decrease	VERB
iajs-4030	155	21	gfr	gfr	NOUN
iajs-4030	155	22	to	to	PART
iajs-4030	155	23	elevate	elevate	VERB
iajs-4030	155	24	serum	serum	NOUN
iajs-4030	155	25	map2	map2	PROPN
iajs-4030	155	26	levels	level	NOUN
iajs-4030	155	27	.	.	PUNCT
iajs-4030	156	1	acknowledgment	acknowledgment	NOUN
iajs-4030	156	2	the	the	DET
iajs-4030	156	3	authors	author	NOUN
iajs-4030	156	4	thank	thank	VERB
iajs-4030	156	5	the	the	DET
iajs-4030	156	6	department	department	NOUN
iajs-4030	156	7	of	of	ADP
iajs-4030	156	8	chemistry	chemistry	NOUN
iajs-4030	156	9	,	,	PUNCT
iajs-4030	156	10	college	college	NOUN
iajs-4030	156	11	of	of	ADP
iajs-4030	156	12	education	education	NOUN
iajs-4030	156	13	for	for	ADP
iajs-4030	156	14	pure	pure	ADJ
iajs-4030	156	15	science	science	NOUN
iajs-4030	156	16	(	(	PUNCT
iajs-4030	156	17	ibn	ibn	PROPN
iajs-4030	156	18	al	al	PROPN
iajs-4030	156	19	-	-	PUNCT
iajs-4030	156	20	haitham	haitham	PROPN
iajs-4030	156	21	)	)	PUNCT
iajs-4030	156	22	,	,	PUNCT
iajs-4030	156	23	university	university	NOUN
iajs-4030	156	24	of	of	ADP
iajs-4030	156	25	baghdad	baghdad	PROPN
iajs-4030	156	26	,	,	PUNCT
iajs-4030	156	27	for	for	ADP
iajs-4030	156	28	its	its	PRON
iajs-4030	156	29	approval	approval	NOUN
iajs-4030	156	30	of	of	ADP
iajs-4030	156	31	the	the	DET
iajs-4030	156	32	research	research	NOUN
iajs-4030	156	33	.	.	PUNCT
iajs-4030	157	1	conflict	conflict	NOUN
iajs-4030	157	2	of	of	ADP
iajs-4030	157	3	interest	interest	NOUN
iajs-4030	157	4	the	the	DET
iajs-4030	157	5	authors	author	NOUN
iajs-4030	157	6	declared	declare	VERB
iajs-4030	157	7	that	that	SCONJ
iajs-4030	157	8	they	they	PRON
iajs-4030	157	9	have	have	VERB
iajs-4030	157	10	no	no	DET
iajs-4030	157	11	conflicts	conflict	NOUN
iajs-4030	157	12	of	of	ADP
iajs-4030	157	13	interest	interest	NOUN
iajs-4030	157	14	.	.	PUNCT
iajs-4030	158	1	funding	funding	NOUN
iajs-4030	158	2	there	there	PRON
iajs-4030	158	3	is	be	VERB
iajs-4030	158	4	no	no	DET
iajs-4030	158	5	funding	funding	NOUN
iajs-4030	158	6	for	for	ADP
iajs-4030	158	7	this	this	DET
iajs-4030	158	8	work	work	NOUN
iajs-4030	158	9	.	.	PUNCT
iajs-4030	159	1	ethical	ethical	ADJ
iajs-4030	159	2	clearance	clearance	NOUN
iajs-4030	159	3	the	the	DET
iajs-4030	159	4	institutional	institutional	ADJ
iajs-4030	159	5	scientific	scientific	ADJ
iajs-4030	159	6	committee	committee	NOUN
iajs-4030	159	7	at	at	ADP
iajs-4030	159	8	the	the	DET
iajs-4030	159	9	university	university	PROPN
iajs-4030	159	10	of	of	ADP
iajs-4030	159	11	baghdad	baghdad	PROPN
iajs-4030	159	12	approved	approve	VERB
iajs-4030	159	13	this	this	DET
iajs-4030	159	14	study	study	NOUN
iajs-4030	159	15	in	in	ADP
iajs-4030	159	16	accordance	accordance	NOUN
iajs-4030	159	17	with	with	ADP
iajs-4030	159	18	the	the	DET
iajs-4030	159	19	declaration	declaration	NOUN
iajs-4030	159	20	of	of	ADP
iajs-4030	159	21	helsinki	helsinki	PROPN
iajs-4030	159	22	for	for	ADP
iajs-4030	159	23	human	human	ADJ
iajs-4030	159	24	studies	study	NOUN
iajs-4030	159	25	,	,	PUNCT
iajs-4030	159	26	which	which	PRON
iajs-4030	159	27	is	be	AUX
iajs-4030	159	28	consistent	consistent	ADJ
iajs-4030	159	29	with	with	ADP
iajs-4030	159	30	the	the	DET
iajs-4030	159	31	instructions	instruction	NOUN
iajs-4030	159	32	of	of	ADP
iajs-4030	159	33	the	the	DET
iajs-4030	159	34	iraqi	iraqi	ADJ
iajs-4030	159	35	ministry	ministry	PROPN
iajs-4030	159	36	of	of	ADP
iajs-4030	159	37	health	health	PROPN
iajs-4030	159	38	and	and	CCONJ
iajs-4030	159	39	environment	environment	NOUN
iajs-4030	159	40	(	(	PUNCT
iajs-4030	159	41	no	no	NOUN
iajs-4030	159	42	.	.	NOUN
iajs-4030	159	43	85954	85954	NUM
iajs-4030	159	44	on	on	ADP
iajs-4030	159	45	22/11/2023	22/11/2023	NUM
iajs-4030	159	46	)	)	PUNCT
iajs-4030	159	47	.	.	PUNCT
iajs-4030	160	1	references	reference	NOUN
iajs-4030	160	2	1	1	NUM
iajs-4030	160	3	.	.	PUNCT
iajs-4030	161	1	ammirati	ammirati	PROPN
iajs-4030	161	2	al	al	PROPN
iajs-4030	161	3	.	.	PROPN
iajs-4030	161	4	chronic	chronic	ADJ
iajs-4030	161	5	kidney	kidney	NOUN
iajs-4030	161	6	disease	disease	NOUN
iajs-4030	161	7	.	.	PUNCT
iajs-4030	162	1	rev	rev	PROPN
iajs-4030	162	2	assoc	assoc	PROPN
iajs-4030	162	3	med	med	PROPN
iajs-4030	162	4	bras	bras	NOUN
iajs-4030	162	5	.	.	PUNCT
iajs-4030	163	1	2020	2020	NUM
iajs-4030	163	2	;	;	PUNCT
iajs-4030	164	1	66(1):s03	66(1):s03	NOUN
iajs-4030	164	2	–	–	PUNCT
iajs-4030	164	3	s09	s09	NOUN
iajs-4030	164	4	.	.	PUNCT
iajs-4030	165	1	https://doi.org/10.1590/1806-9282.66.s1.3	https://doi.org/10.1590/1806-9282.66.s1.3	VERB
iajs-4030	165	2	.	.	PUNCT
iajs-4030	166	1	2	2	X
iajs-4030	166	2	.	.	X
iajs-4030	166	3	ahmed	ahmed	PROPN
iajs-4030	166	4	hs	hs	PROPN
iajs-4030	166	5	,	,	PUNCT
iajs-4030	166	6	abd‑ali	abd‑ali	ADJ
iajs-4030	166	7	e	e	NOUN
iajs-4030	166	8	,	,	PUNCT
iajs-4030	166	9	abdullah	abdullah	PROPN
iajs-4030	166	10	mr	mr	PROPN
iajs-4030	166	11	.	.	PROPN
iajs-4030	166	12	biochemical	biochemical	ADJ
iajs-4030	166	13	study	study	NOUN
iajs-4030	166	14	on	on	ADP
iajs-4030	166	15	diabetic	diabetic	ADJ
iajs-4030	166	16	nephropathy	nephropathy	ADJ
iajs-4030	166	17	patients	patient	NOUN
iajs-4030	166	18	.	.	PUNCT
iajs-4030	167	1	ihjpas	ihjpas	PROPN
iajs-4030	167	2	.	.	PUNCT
iajs-4030	168	1	2010	2010	NUM
iajs-4030	168	2	;	;	PUNCT
iajs-4030	169	1	23(3):1–11	23(3):1–11	NUM
iajs-4030	169	2	.	.	PUNCT
iajs-4030	169	3	https://jih.uobaghdad.edu.iq/index.php/j/article/view/899/768	https://jih.uobaghdad.edu.iq/index.php/j/article/view/899/768	PROPN
iajs-4030	169	4	.	.	PUNCT
iajs-4030	170	1	3	3	X
iajs-4030	170	2	.	.	X
iajs-4030	170	3	mohammed	mohammed	PROPN
iajs-4030	170	4	ms	ms	PROPN
iajs-4030	170	5	,	,	PUNCT
iajs-4030	170	6	ahmed	ahmed	PROPN
iajs-4030	170	7	hs	hs	PROPN
iajs-4030	170	8	.	.	PROPN
iajs-4030	170	9	plasminogen	plasminogen	NOUN
iajs-4030	170	10	activator	activator	NOUN
iajs-4030	170	11	urokinase	urokinase	NOUN
iajs-4030	170	12	receptor	receptor	NOUN
iajs-4030	170	13	as	as	ADP
iajs-4030	170	14	a	a	DET
iajs-4030	170	15	diagnostic	diagnostic	ADJ
iajs-4030	170	16	and	and	CCONJ
iajs-4030	170	17	prognostic	prognostic	ADJ
iajs-4030	170	18	biomarker	biomarker	NOUN
iajs-4030	170	19	in	in	ADP
iajs-4030	170	20	type	type	NOUN
iajs-4030	170	21	2	2	NUM
iajs-4030	170	22	diabetic	diabetic	ADJ
iajs-4030	170	23	patients	patient	NOUN
iajs-4030	170	24	with	with	ADP
iajs-4030	170	25	cardiovascular	cardiovascular	ADJ
iajs-4030	170	26	disease	disease	NOUN
iajs-4030	170	27	.	.	PUNCT
iajs-4030	171	1	j	j	PROPN
iajs-4030	171	2	cardiovasc	cardiovasc	PROPN
iajs-4030	171	3	thorac	thorac	PROPN
iajs-4030	171	4	res	re	NOUN
iajs-4030	171	5	.	.	PUNCT
iajs-4030	171	6	2023	2023	NUM
iajs-4030	171	7	;	;	PUNCT
iajs-4030	171	8	15(3	15(3	NUM
iajs-4030	171	9	):	):	PUNCT
iajs-4030	171	10	154–160	154–160	NUM
iajs-4030	171	11	.	.	PUNCT
iajs-4030	172	1	https://doi.org/10.34172%2fjcvtr.2023.32895	https://doi.org/10.34172%2fjcvtr.2023.32895	NOUN
iajs-4030	172	2	.	.	PUNCT
iajs-4030	173	1	4	4	NUM
iajs-4030	173	2	.	.	NOUN
iajs-4030	173	3	verdier	verdier	PROPN
iajs-4030	173	4	v	v	NOUN
iajs-4030	173	5	,	,	PUNCT
iajs-4030	173	6	soulage	soulage	NOUN
iajs-4030	173	7	co	co	NOUN
iajs-4030	173	8	,	,	PUNCT
iajs-4030	173	9	koppe	koppe	PROPN
iajs-4030	173	10	l.	l.	PROPN
iajs-4030	173	11	new	new	ADJ
iajs-4030	173	12	clinical	clinical	ADJ
iajs-4030	173	13	evidence	evidence	NOUN
iajs-4030	173	14	for	for	ADP
iajs-4030	173	15	urea	urea	NOUN
iajs-4030	173	16	toxicity	toxicity	NOUN
iajs-4030	173	17	.	.	PUNCT
iajs-4030	174	1	nephrol	nephrol	PROPN
iajs-4030	174	2	dial	dial	NOUN
iajs-4030	174	3	transpl	transpl	NOUN
iajs-4030	174	4	.	.	PUNCT
iajs-4030	175	1	2022	2022	NUM
iajs-4030	175	2	;	;	PUNCT
iajs-4030	176	1	37(1):1–4	37(1):1–4	NOUN
iajs-4030	176	2	.	.	PUNCT
iajs-4030	177	1	https://doi.org/10.1093/ndt/gfab269	https://doi.org/10.1093/ndt/gfab269	PROPN
iajs-4030	177	2	.	.	PUNCT
iajs-4030	178	1	5	5	X
iajs-4030	178	2	.	.	PUNCT
iajs-4030	178	3	ahmed	ahmed	PROPN
iajs-4030	178	4	hs	hs	PROPN
iajs-4030	178	5	.	.	PROPN
iajs-4030	178	6	serum	serum	PROPN
iajs-4030	178	7	adropin	adropin	NOUN
iajs-4030	178	8	and	and	CCONJ
iajs-4030	178	9	apelin	apelin	PROPN
iajs-4030	178	10	as	as	ADP
iajs-4030	178	11	potential	potential	ADJ
iajs-4030	178	12	markers	marker	NOUN
iajs-4030	178	13	predicting	predict	VERB
iajs-4030	178	14	acute	acute	ADJ
iajs-4030	178	15	heart	heart	NOUN
iajs-4030	178	16	failure‑	failure‑	ADP
iajs-4030	178	17	associated	associate	VERB
iajs-4030	178	18	renal	renal	ADJ
iajs-4030	178	19	dysfunction	dysfunction	NOUN
iajs-4030	178	20	among	among	ADP
iajs-4030	178	21	elderly	elderly	ADJ
iajs-4030	178	22	iraqi	iraqi	ADJ
iajs-4030	178	23	patients	patient	NOUN
iajs-4030	178	24	.	.	PUNCT
iajs-4030	179	1	ann	ann	PROPN
iajs-4030	179	2	trop	trop	X
iajs-4030	179	3	med	med	ADJ
iajs-4030	179	4	public	public	ADJ
iajs-4030	179	5	health	health	NOUN
iajs-4030	179	6	.	.	PUNCT
iajs-4030	180	1	2020	2020	NUM
iajs-4030	180	2	;	;	PUNCT
iajs-4030	180	3	23(s10):1–15	23(s10):1–15	NUM
iajs-4030	180	4	.	.	PUNCT
iajs-4030	181	1	http://dx.doi.org/10.36295/asro.2020.231024	http://dx.doi.org/10.36295/asro.2020.231024	NOUN
iajs-4030	181	2	.	.	PUNCT
iajs-4030	182	1	6	6	NUM
iajs-4030	182	2	.	.	X
iajs-4030	182	3	obert	obert	PROPN
iajs-4030	182	4	la	la	PROPN
iajs-4030	182	5	,	,	PUNCT
iajs-4030	182	6	elmore	elmore	PROPN
iajs-4030	182	7	sa	sa	PROPN
iajs-4030	182	8	,	,	PUNCT
iajs-4030	182	9	ennulat	ennulat	NOUN
iajs-4030	182	10	d	d	PROPN
iajs-4030	182	11	,	,	PUNCT
iajs-4030	182	12	frazier	frazier	PROPN
iajs-4030	182	13	ks	ks	PROPN
iajs-4030	182	14	.	.	PROPN
iajs-4030	183	1	a	a	DET
iajs-4030	183	2	review	review	NOUN
iajs-4030	183	3	of	of	ADP
iajs-4030	183	4	specific	specific	ADJ
iajs-4030	183	5	biomarkers	biomarker	NOUN
iajs-4030	183	6	of	of	ADP
iajs-4030	183	7	chronic	chronic	ADJ
iajs-4030	183	8	renal	renal	ADJ
iajs-4030	183	9	injury	injury	NOUN
iajs-4030	183	10	and	and	CCONJ
iajs-4030	183	11	their	their	PRON
iajs-4030	183	12	potential	potential	ADJ
iajs-4030	183	13	application	application	NOUN
iajs-4030	183	14	in	in	ADP
iajs-4030	183	15	nonclinical	nonclinical	ADJ
iajs-4030	183	16	safety	safety	NOUN
iajs-4030	183	17	assessment	assessment	NOUN
iajs-4030	183	18	studies	study	NOUN
iajs-4030	183	19	.	.	PUNCT
iajs-4030	184	1	toxicol	toxicol	PROPN
iajs-4030	184	2	pathol	pathol	NOUN
iajs-4030	184	3	.	.	PUNCT
iajs-4030	184	4	2021	2021	NUM
iajs-4030	184	5	;	;	PUNCT
iajs-4030	184	6	49(5	49(5	NUM
iajs-4030	184	7	):	):	PUNCT
iajs-4030	184	8	996–1023	996–1023	NUM
iajs-4030	184	9	.	.	PUNCT
iajs-4030	185	1	https://doi.org/10.1177/0192623320985045	https://doi.org/10.1177/0192623320985045	PROPN
iajs-4030	185	2	.	.	PUNCT
iajs-4030	185	3	7	7	X
iajs-4030	185	4	.	.	X
iajs-4030	185	5	kumahor	kumahor	PROPN
iajs-4030	185	6	ek	ek	PROPN
iajs-4030	185	7	.	.	PUNCT
iajs-4030	186	1	the	the	DET
iajs-4030	186	2	biochemical	biochemical	ADJ
iajs-4030	186	3	basis	basis	NOUN
iajs-4030	186	4	of	of	ADP
iajs-4030	186	5	renal	renal	ADJ
iajs-4030	186	6	diseases	disease	NOUN
iajs-4030	186	7	.	.	PUNCT
iajs-4030	187	1	in	in	ADP
iajs-4030	187	2	:	:	PUNCT
iajs-4030	187	3	current	current	ADJ
iajs-4030	187	4	trends	trend	NOUN
iajs-4030	187	5	in	in	ADP
iajs-4030	187	6	the	the	DET
iajs-4030	187	7	diagnosis	diagnosis	NOUN
iajs-4030	187	8	and	and	CCONJ
iajs-4030	187	9	management	management	NOUN
iajs-4030	187	10	of	of	ADP
iajs-4030	187	11	metabolic	metabolic	NOUN
iajs-4030	187	12	disorders	disorder	NOUN
iajs-4030	187	13	.	.	PUNCT
iajs-4030	188	1	crc	crc	PROPN
iajs-4030	188	2	press	press	PROPN
iajs-4030	188	3	;	;	PUNCT
iajs-4030	188	4	2024	2024	NUM
iajs-4030	188	5	.	.	PUNCT
iajs-4030	189	1	p.	p.	NOUN
iajs-4030	189	2	 	 	SPACE
iajs-4030	189	3	185–200	185–200	NUM
iajs-4030	189	4	.	.	PUNCT
iajs-4030	190	1	http://dx.doi.org/10.1201/9781003384823-11	http://dx.doi.org/10.1201/9781003384823-11	PROPN
iajs-4030	190	2	.	.	PROPN
iajs-4030	190	3	8	8	NUM
iajs-4030	190	4	.	.	PUNCT
iajs-4030	191	1	rodriguez‑ballestas	rodriguez‑ballesta	NOUN
iajs-4030	191	2	e	e	X
iajs-4030	191	3	,	,	PUNCT
iajs-4030	191	4	reid‑adam	reid‑adam	PROPN
iajs-4030	191	5	j.	j.	PROPN
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iajs-4030	191	7	syndrome	syndrome	PROPN
iajs-4030	191	8	.	.	PUNCT
iajs-4030	192	1	curr	curr	PROPN
iajs-4030	192	2	pediatr	pediatr	PROPN
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iajs-4030	192	4	.	.	PROPN
iajs-4030	192	5	2022	2022	NUM
iajs-4030	192	6	;	;	PUNCT
iajs-4030	192	7	43(2):87–99	43(2):87–99	NUM
iajs-4030	192	8	.	.	X
iajs-4030	193	1	https://doi.org/10.1542/pir.2020-001230	https://doi.org/10.1542/pir.2020-001230	PROPN
iajs-4030	193	2	.	.	PUNCT
iajs-4030	194	1	https://doi.org/10.1590/1806-9282.66.s1.3	https://doi.org/10.1590/1806-9282.66.s1.3	PROPN
iajs-4030	194	2	https://jih.uobaghdad.edu.iq/index.php/j/article/view/899/768	https://jih.uobaghdad.edu.iq/index.php/j/article/view/899/768	PROPN
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iajs-4030	194	4	https://doi.org/10.1093/ndt/gfab269	https://doi.org/10.1093/ndt/gfab269	AUX
iajs-4030	194	5	http://dx.doi.org/10.36295/asro.2020.231024	http://dx.doi.org/10.36295/asro.2020.231024	NOUN
iajs-4030	194	6	https://doi.org/10.1177/0192623320985045	https://doi.org/10.1177/0192623320985045	PROPN
iajs-4030	194	7	http://dx.doi.org/10.1201/9781003384823-11	http://dx.doi.org/10.1201/9781003384823-11	PROPN
iajs-4030	195	1	https://doi.org/10.1542/pir.2020-001230	https://doi.org/10.1542/pir.2020-001230	PROPN
iajs-4030	195	2	ihjpas	ihjpas	PROPN
iajs-4030	195	3	.	.	PUNCT
iajs-4030	196	1	38(3)2025	38(3)2025	NUM
iajs-4030	196	2	281	281	NUM
iajs-4030	196	3	9	9	NUM
iajs-4030	196	4	.	.	PUNCT
iajs-4030	197	1	ahmed	ahmed	PROPN
iajs-4030	197	2	hs	hs	PROPN
iajs-4030	197	3	.	.	PROPN
iajs-4030	197	4	obesity	obesity	NOUN
iajs-4030	197	5	and	and	CCONJ
iajs-4030	197	6	breast	breast	NOUN
iajs-4030	197	7	cancer	cancer	NOUN
iajs-4030	197	8	:	:	PUNCT
iajs-4030	197	9	circulating	circulate	VERB
iajs-4030	197	10	adipokines	adipokine	NOUN
iajs-4030	197	11	and	and	CCONJ
iajs-4030	197	12	their	their	PRON
iajs-4030	197	13	potential	potential	ADJ
iajs-4030	197	14	diagnostic	diagnostic	NOUN
iajs-4030	197	15	as	as	ADP
iajs-4030	197	16	risk	risk	NOUN
iajs-4030	197	17	biomarkers	biomarker	NOUN
iajs-4030	197	18	.	.	PUNCT
iajs-4030	198	1	int	int	PROPN
iajs-4030	198	2	j	j	PROPN
iajs-4030	198	3	res	res	PROPN
iajs-4030	198	4	pharm	pharm	PROPN
iajs-4030	198	5	sci	sci	PROPN
iajs-4030	198	6	.	.	PROPN
iajs-4030	198	7	2020	2020	NUM
iajs-4030	198	8	;	;	PUNCT
iajs-4030	198	9	11(3):3061–3068	11(3):3061–3068	NUM
iajs-4030	198	10	.	.	X
iajs-4030	198	11	https://ijrps.com/index.php/home/article/view/599	https://ijrps.com/index.php/home/article/view/599	NOUN
iajs-4030	198	12	.	.	PUNCT
iajs-4030	199	1	10	10	NUM
iajs-4030	199	2	.	.	X
iajs-4030	200	1	stetler‑stevenson	stetler‑stevenson	NOUN
iajs-4030	200	2	wg	wg	ADJ
iajs-4030	200	3	.	.	PUNCT
iajs-4030	201	1	the	the	DET
iajs-4030	201	2	continuing	continue	VERB
iajs-4030	201	3	saga	saga	NOUN
iajs-4030	201	4	of	of	ADP
iajs-4030	201	5	tissue	tissue	NOUN
iajs-4030	201	6	inhibitor	inhibitor	NOUN
iajs-4030	201	7	of	of	ADP
iajs-4030	201	8	metalloproteinase	metalloproteinase	PROPN
iajs-4030	201	9	2	2	NUM
iajs-4030	201	10	:	:	PUNCT
iajs-4030	201	11	emerging	emerge	VERB
iajs-4030	201	12	roles	role	NOUN
iajs-4030	201	13	in	in	ADP
iajs-4030	201	14	tissue	tissue	NOUN
iajs-4030	201	15	homeostasis	homeostasis	NOUN
iajs-4030	201	16	and	and	CCONJ
iajs-4030	201	17	cancer	cancer	NOUN
iajs-4030	201	18	progression	progression	NOUN
iajs-4030	201	19	.	.	PUNCT
iajs-4030	202	1	am	be	AUX
iajs-4030	202	2	j	j	PROPN
iajs-4030	202	3	pathol	pathol	NOUN
iajs-4030	202	4	.	.	PUNCT
iajs-4030	203	1	2023	2023	NUM
iajs-4030	203	2	;	;	PUNCT
iajs-4030	203	3	193(5):579–590	193(5):579–590	NUM
iajs-4030	203	4	.	.	PUNCT
iajs-4030	204	1	https://doi.org/10.1016/j.ajpath.2023.01.007	https://doi.org/10.1016/j.ajpath.2023.01.007	VERB
iajs-4030	204	2	.	.	PUNCT
iajs-4030	205	1	11	11	NUM
iajs-4030	205	2	.	.	PUNCT
iajs-4030	205	3	yan	yan	PROPN
iajs-4030	206	1	z	z	PROPN
iajs-4030	206	2	,	,	PUNCT
iajs-4030	206	3	wang	wang	PROPN
iajs-4030	206	4	g	g	PROPN
iajs-4030	206	5	,	,	PUNCT
iajs-4030	206	6	shi	shi	PROPN
iajs-4030	206	7	x.	x.	PROPN
iajs-4030	206	8	advances	advance	VERB
iajs-4030	206	9	in	in	ADP
iajs-4030	206	10	the	the	DET
iajs-4030	206	11	progression	progression	NOUN
iajs-4030	206	12	and	and	CCONJ
iajs-4030	206	13	prognosis	prognosis	NOUN
iajs-4030	206	14	biomarkers	biomarker	NOUN
iajs-4030	206	15	of	of	ADP
iajs-4030	206	16	chronic	chronic	ADJ
iajs-4030	206	17	kidney	kidney	NOUN
iajs-4030	206	18	disease	disease	NOUN
iajs-4030	206	19	.	.	PUNCT
iajs-4030	207	1	front	front	ADJ
iajs-4030	207	2	pharmacol	pharmacol	PROPN
iajs-4030	207	3	.	.	PUNCT
iajs-4030	208	1	2021;12:785375	2021;12:785375	NUM
iajs-4030	208	2	.	.	PUNCT
iajs-4030	209	1	https://doi.org/10.3389/fphar.2021.785375	https://doi.org/10.3389/fphar.2021.785375	PROPN
iajs-4030	209	2	.	.	PROPN
iajs-4030	210	1	12	12	NUM
iajs-4030	210	2	.	.	PUNCT
iajs-4030	211	1	romagnani	romagnani	PROPN
iajs-4030	211	2	p	p	X
iajs-4030	211	3	,	,	PUNCT
iajs-4030	211	4	remuzzi	remuzzi	VERB
iajs-4030	211	5	g	g	NOUN
iajs-4030	211	6	,	,	PUNCT
iajs-4030	211	7	glassock	glassock	NOUN
iajs-4030	211	8	r	r	NOUN
iajs-4030	211	9	,	,	PUNCT
iajs-4030	211	10	levin	levin	PROPN
iajs-4030	211	11	a	a	PROPN
iajs-4030	211	12	,	,	PUNCT
iajs-4030	211	13	jager	jager	PROPN
iajs-4030	211	14	kj	kj	PROPN
iajs-4030	211	15	,	,	PUNCT
iajs-4030	211	16	tonelli	tonelli	PROPN
iajs-4030	211	17	m	m	PROPN
iajs-4030	211	18	,	,	PUNCT
iajs-4030	211	19	anders	anders	PROPN
iajs-4030	211	20	hj	hj	PROPN
iajs-4030	211	21	.	.	PROPN
iajs-4030	211	22	chronic	chronic	ADJ
iajs-4030	211	23	kidney	kidney	NOUN
iajs-4030	211	24	disease	disease	NOUN
iajs-4030	211	25	.	.	PUNCT
iajs-4030	212	1	nat	nat	PROPN
iajs-4030	212	2	rev	rev	VERB
iajs-4030	212	3	dis	dis	PROPN
iajs-4030	212	4	primers	primer	NOUN
iajs-4030	212	5	.	.	PUNCT
iajs-4030	213	1	2017	2017	NUM
iajs-4030	213	2	;	;	PUNCT
iajs-4030	213	3	3(1):1–24	3(1):1–24	NUM
iajs-4030	213	4	.	.	PUNCT
iajs-4030	214	1	https://doi.org/	https://doi.org/	PROPN
iajs-4030	214	2	10.1038	10.1038	NUM
iajs-4030	214	3	/	/	SYM
iajs-4030	214	4	nrdp.2017.88	nrdp.2017.88	NOUN
iajs-4030	214	5	.	.	PUNCT
iajs-4030	215	1	13	13	NUM
iajs-4030	215	2	.	.	PUNCT
iajs-4030	215	3	perazella	perazella	PROPN
iajs-4030	215	4	ma	ma	PROPN
iajs-4030	215	5	,	,	PUNCT
iajs-4030	215	6	nast	nast	PROPN
iajs-4030	215	7	cc	cc	PROPN
iajs-4030	215	8	.	.	PROPN
iajs-4030	215	9	chronic	chronic	ADJ
iajs-4030	215	10	tubulointerstitial	tubulointerstitial	ADJ
iajs-4030	215	11	disease	disease	NOUN
iajs-4030	215	12	.	.	PUNCT
iajs-4030	216	1	in	in	ADP
iajs-4030	216	2	:	:	PUNCT
iajs-4030	216	3	national	national	ADJ
iajs-4030	216	4	kidney	kidney	PROPN
iajs-4030	216	5	foundation	foundation	NOUN
iajs-4030	216	6	primer	primer	NOUN
iajs-4030	216	7	on	on	ADP
iajs-4030	216	8	kidney	kidney	NOUN
iajs-4030	216	9	diseases	disease	NOUN
iajs-4030	216	10	,	,	PUNCT
iajs-4030	216	11	e	e	NOUN
iajs-4030	216	12	-	-	NOUN
iajs-4030	216	13	book	book	NOUN
iajs-4030	216	14	.	.	PUNCT
iajs-4030	216	15	philadelphia	philadelphia	PROPN
iajs-4030	216	16	(	(	PUNCT
iajs-4030	216	17	pa	pa	PROPN
iajs-4030	216	18	):	):	PUNCT
iajs-4030	216	19	elsevier	elsevier	NOUN
iajs-4030	216	20	;	;	PUNCT
iajs-4030	216	21	2022	2022	NUM
iajs-4030	216	22	;	;	PUNCT
iajs-4030	216	23	p.	p.	NOUN
iajs-4030	216	24	 	 	SPACE
iajs-4030	216	25	406	406	NUM
iajs-4030	216	26	.	.	PUNCT
iajs-4030	216	27	14	14	NUM
iajs-4030	216	28	.	.	PUNCT
iajs-4030	216	29	national	national	PROPN
iajs-4030	216	30	kidney	kidney	PROPN
iajs-4030	216	31	foundation	foundation	PROPN
iajs-4030	216	32	.	.	PUNCT
iajs-4030	217	1	k	k	X
iajs-4030	217	2	/	/	SYM
iajs-4030	217	3	doqi	doqi	PROPN
iajs-4030	217	4	clinical	clinical	ADJ
iajs-4030	217	5	practice	practice	NOUN
iajs-4030	217	6	guidelines	guideline	NOUN
iajs-4030	217	7	for	for	ADP
iajs-4030	217	8	chronic	chronic	ADJ
iajs-4030	217	9	kidney	kidney	NOUN
iajs-4030	217	10	disease	disease	NOUN
iajs-4030	217	11	:	:	PUNCT
iajs-4030	217	12	evaluation	evaluation	NOUN
iajs-4030	217	13	,	,	PUNCT
iajs-4030	217	14	classification	classification	NOUN
iajs-4030	217	15	,	,	PUNCT
iajs-4030	217	16	and	and	CCONJ
iajs-4030	217	17	stratification	stratification	NOUN
iajs-4030	217	18	.	.	PUNCT
iajs-4030	218	1	am	be	AUX
iajs-4030	218	2	j	j	PROPN
iajs-4030	218	3	kidney	kidney	PROPN
iajs-4030	218	4	dis	dis	PROPN
iajs-4030	218	5	.	.	PUNCT
iajs-4030	219	1	2002	2002	NUM
iajs-4030	219	2	;	;	PUNCT
iajs-4030	219	3	39(2	39(2	NUM
iajs-4030	219	4	 	 	SPACE
iajs-4030	219	5	suppl	suppl	ADJ
iajs-4030	219	6	 	 	SPACE
iajs-4030	219	7	1):s1–266	1):s1–266	PROPN
iajs-4030	219	8	.	.	PUNCT
iajs-4030	220	1	pmid	pmid	NOUN
iajs-4030	220	2	:	:	PUNCT
iajs-4030	220	3	11904577	11904577	NUM
iajs-4030	220	4	.	.	PUNCT
iajs-4030	221	1	15	15	NUM
iajs-4030	221	2	.	.	PUNCT
iajs-4030	222	1	kalantar‑zadeh	kalantar‑zadeh	PUNCT
iajs-4030	223	1	k	k	PROPN
iajs-4030	223	2	,	,	PUNCT
iajs-4030	223	3	li	li	PROPN
iajs-4030	223	4	pk	pk	PROPN
iajs-4030	223	5	,	,	PUNCT
iajs-4030	223	6	kovesdy	kovesdy	VERB
iajs-4030	223	7	cp	cp	PROPN
iajs-4030	223	8	,	,	PUNCT
iajs-4030	223	9	liyanage	liyanage	NOUN
iajs-4030	223	10	t	t	PROPN
iajs-4030	223	11	,	,	PUNCT
iajs-4030	223	12	levin	levin	PROPN
iajs-4030	223	13	a	a	PROPN
iajs-4030	223	14	,	,	PUNCT
iajs-4030	223	15	tonelli	tonelli	PROPN
iajs-4030	223	16	m.	m.	PROPN
iajs-4030	223	17	chronic	chronic	PROPN
iajs-4030	223	18	kidney	kidney	NOUN
iajs-4030	223	19	disease	disease	NOUN
iajs-4030	223	20	and	and	CCONJ
iajs-4030	223	21	the	the	DET
iajs-4030	223	22	global	global	ADJ
iajs-4030	223	23	public	public	ADJ
iajs-4030	223	24	health	health	NOUN
iajs-4030	223	25	challenge	challenge	NOUN
iajs-4030	223	26	:	:	PUNCT
iajs-4030	223	27	the	the	DET
iajs-4030	223	28	2021	2021	NUM
iajs-4030	223	29	kdigo	kdigo	PROPN
iajs-4030	223	30	guidelines	guideline	NOUN
iajs-4030	223	31	and	and	CCONJ
iajs-4030	223	32	future	future	ADJ
iajs-4030	223	33	outlook	outlook	NOUN
iajs-4030	223	34	.	.	PUNCT
iajs-4030	224	1	lancet	lancet	PROPN
iajs-4030	224	2	.	.	PUNCT
iajs-4030	225	1	2021	2021	NUM
iajs-4030	225	2	;	;	PUNCT
iajs-4030	225	3	398(10311):786–802	398(10311):786–802	NUM
iajs-4030	225	4	.	.	PUNCT
iajs-4030	226	1	16	16	NUM
iajs-4030	226	2	.	.	PUNCT
iajs-4030	227	1	francis	francis	PROPN
iajs-4030	227	2	a	a	PROPN
iajs-4030	227	3	,	,	PUNCT
iajs-4030	227	4	harhay	harhay	PROPN
iajs-4030	227	5	mn	mn	PROPN
iajs-4030	227	6	,	,	PUNCT
iajs-4030	227	7	ong	ong	PROPN
iajs-4030	227	8	a	a	X
iajs-4030	227	9	,	,	PUNCT
iajs-4030	227	10	tummalapalli	tummalapalli	PROPN
iajs-4030	227	11	sl	sl	PROPN
iajs-4030	227	12	,	,	PUNCT
iajs-4030	227	13	ortiz	ortiz	PROPN
iajs-4030	227	14	a	a	PROPN
iajs-4030	227	15	,	,	PUNCT
iajs-4030	227	16	fogo	fogo	PROPN
iajs-4030	227	17	ab	ab	PROPN
iajs-4030	227	18	,	,	PUNCT
iajs-4030	227	19	jha	jha	PROPN
iajs-4030	227	20	v.	v.	PROPN
iajs-4030	227	21	chronic	chronic	ADJ
iajs-4030	227	22	kidney	kidney	NOUN
iajs-4030	227	23	disease	disease	NOUN
iajs-4030	227	24	and	and	CCONJ
iajs-4030	227	25	the	the	DET
iajs-4030	227	26	global	global	ADJ
iajs-4030	227	27	public	public	ADJ
iajs-4030	227	28	health	health	NOUN
iajs-4030	227	29	agenda	agenda	NOUN
iajs-4030	227	30	:	:	PUNCT
iajs-4030	227	31	an	an	DET
iajs-4030	227	32	international	international	ADJ
iajs-4030	227	33	consensus	consensus	NOUN
iajs-4030	227	34	.	.	PUNCT
iajs-4030	228	1	nat	nat	PROPN
iajs-4030	228	2	rev	rev	VERB
iajs-4030	228	3	nephrol	nephrol	PROPN
iajs-4030	228	4	.	.	PUNCT
iajs-4030	229	1	2024:1	2024:1	NUM
iajs-4030	229	2	–	–	PUNCT
iajs-4030	229	3	13	13	NUM
iajs-4030	229	4	.	.	PUNCT
iajs-4030	229	5	https://doi.org/10.1038/s41581-024-00820-6	https://doi.org/10.1038/s41581-024-00820-6	NUM
iajs-4030	229	6	.	.	PUNCT
iajs-4030	230	1	17	17	NUM
iajs-4030	230	2	.	.	PUNCT
iajs-4030	231	1	ibm	ibm	PROPN
iajs-4030	231	2	.	.	PUNCT
iajs-4030	231	3	statistical	statistical	ADJ
iajs-4030	231	4	package	package	NOUN
iajs-4030	231	5	for	for	ADP
iajs-4030	231	6	the	the	DET
iajs-4030	231	7	social	social	ADJ
iajs-4030	231	8	sciences	science	NOUN
iajs-4030	231	9	(	(	PUNCT
iajs-4030	231	10	spss)–ibm	spss)–ibm	PROPN
iajs-4030	231	11	v29	v29	NOUN
iajs-4030	231	12	.	.	PUNCT
iajs-4030	232	1	chicago	chicago	PROPN
iajs-4030	232	2	(	(	PUNCT
iajs-4030	232	3	il	il	PROPN
iajs-4030	232	4	):	):	PUNCT
iajs-4030	232	5	ibm	ibm	PROPN
iajs-4030	232	6	corp	corp	PROPN
iajs-4030	232	7	;	;	PUNCT
iajs-4030	232	8	2022	2022	NUM
iajs-4030	232	9	.	.	PUNCT
iajs-4030	233	1	18	18	NUM
iajs-4030	233	2	.	.	PUNCT
iajs-4030	234	1	lin	lin	PROPN
iajs-4030	234	2	r	r	PROPN
iajs-4030	234	3	,	,	PUNCT
iajs-4030	234	4	mcdonald	mcdonald	NOUN
iajs-4030	234	5	g	g	PROPN
iajs-4030	234	6	,	,	PUNCT
iajs-4030	234	7	jolly	jolly	PROPN
iajs-4030	234	8	t	t	PROPN
iajs-4030	234	9	,	,	PUNCT
iajs-4030	234	10	batten	batten	NOUN
iajs-4030	234	11	a	a	DET
iajs-4030	234	12	,	,	PUNCT
iajs-4030	234	13	chacko	chacko	NOUN
iajs-4030	234	14	b.	b.	PROPN
iajs-4030	235	1	a	a	DET
iajs-4030	235	2	systematic	systematic	ADJ
iajs-4030	235	3	review	review	NOUN
iajs-4030	235	4	of	of	ADP
iajs-4030	235	5	prophylactic	prophylactic	ADJ
iajs-4030	235	6	anticoagulation	anticoagulation	NOUN
iajs-4030	235	7	in	in	ADP
iajs-4030	235	8	nephrotic	nephrotic	ADJ
iajs-4030	235	9	syndrome	syndrome	NOUN
iajs-4030	235	10	.	.	PUNCT
iajs-4030	236	1	kidney	kidney	PROPN
iajs-4030	236	2	int	int	PROPN
iajs-4030	236	3	rep	rep	PROPN
iajs-4030	236	4	.	.	PROPN
iajs-4030	236	5	2020	2020	NUM
iajs-4030	236	6	;	;	PUNCT
iajs-4030	236	7	5(4):435–447	5(4):435–447	NUM
iajs-4030	236	8	.	.	PUNCT
iajs-4030	236	9	https://doi.org/	https://doi.org/	VERB
iajs-4030	236	10	10.1016	10.1016	NUM
iajs-4030	236	11	/	/	SYM
iajs-4030	236	12	j.ekir.2019.12.001	j.ekir.2019.12.001	PROPN
iajs-4030	236	13	.	.	PROPN
iajs-4030	237	1	19	19	NUM
iajs-4030	237	2	.	.	NUM
iajs-4030	237	3	noronha	noronha	PROPN
iajs-4030	237	4	il	il	PROPN
iajs-4030	237	5	,	,	PUNCT
iajs-4030	237	6	santa	santa	PROPN
iajs-4030	237	7	-	-	PUNCT
iajs-4030	237	8	catharina	catharina	PROPN
iajs-4030	237	9	gp	gp	NOUN
iajs-4030	237	10	,	,	PUNCT
iajs-4030	237	11	andrade	andrade	PROPN
iajs-4030	237	12	l	l	PROPN
iajs-4030	237	13	,	,	PUNCT
iajs-4030	237	14	coelho	coelho	PROPN
iajs-4030	237	15	va	va	PROPN
iajs-4030	237	16	,	,	PUNCT
iajs-4030	237	17	jacob	jacob	PROPN
iajs-4030	237	18	-	-	PUNCT
iajs-4030	237	19	filho	filho	PROPN
iajs-4030	237	20	w	w	PROPN
iajs-4030	237	21	,	,	PUNCT
iajs-4030	237	22	elias	elias	PROPN
iajs-4030	237	23	rm	rm	PROPN
iajs-4030	237	24	.	.	PUNCT
iajs-4030	237	25	glomerular	glomerular	ADJ
iajs-4030	237	26	filtration	filtration	NOUN
iajs-4030	237	27	in	in	ADP
iajs-4030	237	28	the	the	DET
iajs-4030	237	29	aging	age	VERB
iajs-4030	237	30	population	population	NOUN
iajs-4030	237	31	.	.	PUNCT
iajs-4030	238	1	front	front	PROPN
iajs-4030	238	2	med	med	PROPN
iajs-4030	238	3	.	.	PUNCT
iajs-4030	238	4	2022	2022	NUM
iajs-4030	238	5	;	;	PUNCT
iajs-4030	238	6	9:769329	9:769329	X
iajs-4030	238	7	.	.	PUNCT
iajs-4030	239	1	https://doi.org/10.3389/fmed.2022.769329	https://doi.org/10.3389/fmed.2022.769329	PROPN
iajs-4030	239	2	.	.	PROPN
iajs-4030	240	1	20	20	NUM
iajs-4030	240	2	.	.	PUNCT
iajs-4030	241	1	mohanty	mohanty	PROPN
iajs-4030	241	2	sk	sk	PROPN
iajs-4030	241	3	,	,	PUNCT
iajs-4030	241	4	veerabhadrappa	veerabhadrappa	NOUN
iajs-4030	241	5	b	b	PROPN
iajs-4030	241	6	,	,	PUNCT
iajs-4030	241	7	majhi	majhi	NOUN
iajs-4030	241	8	a	a	NOUN
iajs-4030	241	9	,	,	PUNCT
iajs-4030	241	10	suchiang	suchiang	PROPN
iajs-4030	241	11	k	k	NOUN
iajs-4030	241	12	,	,	PUNCT
iajs-4030	241	13	dyavaiah	dyavaiah	PROPN
iajs-4030	241	14	m.	m.	NOUN
iajs-4030	241	15	age	age	NOUN
iajs-4030	241	16	-	-	PUNCT
iajs-4030	241	17	related	relate	VERB
iajs-4030	241	18	disease	disease	NOUN
iajs-4030	241	19	:	:	PUNCT
iajs-4030	241	20	kidneys	kidney	NOUN
iajs-4030	241	21	.	.	PUNCT
iajs-4030	242	1	in	in	ADP
iajs-4030	242	2	:	:	PUNCT
iajs-4030	242	3	academic	academic	ADJ
iajs-4030	242	4	press	press	NOUN
iajs-4030	242	5	,	,	PUNCT
iajs-4030	242	6	2024	2024	NUM
iajs-4030	242	7	;	;	PUNCT
iajs-4030	243	1	p.	p.	PROPN
iajs-4030	243	2	 	 	SPACE
iajs-4030	243	3	91–117	91–117	PROPN
iajs-4030	243	4	.	.	PUNCT
iajs-4030	244	1	http://dx.doi.org/10.1016/b978-0-443-155000.00003-7	http://dx.doi.org/10.1016/b978-0-443-155000.00003-7	X
iajs-4030	244	2	.	.	PUNCT
iajs-4030	245	1	21	21	NUM
iajs-4030	245	2	.	.	PUNCT
iajs-4030	246	1	kalantar‑zadeh	kalantar‑zadeh	X
iajs-4030	247	1	k	k	PROPN
iajs-4030	247	2	,	,	PUNCT
iajs-4030	247	3	jafar	jafar	PROPN
iajs-4030	247	4	th	th	PROPN
iajs-4030	247	5	,	,	PUNCT
iajs-4030	247	6	nitsch	nitsch	PROPN
iajs-4030	247	7	d	d	PROPN
iajs-4030	247	8	,	,	PUNCT
iajs-4030	247	9	neuen	neuen	PROPN
iajs-4030	247	10	bl	bl	PROPN
iajs-4030	247	11	,	,	PUNCT
iajs-4030	247	12	perkovic	perkovic	ADJ
iajs-4030	247	13	v.	v.	ADP
iajs-4030	247	14	chronic	chronic	ADJ
iajs-4030	247	15	kidney	kidney	NOUN
iajs-4030	247	16	disease	disease	NOUN
iajs-4030	247	17	.	.	PUNCT
iajs-4030	248	1	lancet	lancet	PROPN
iajs-4030	248	2	.	.	PUNCT
iajs-4030	249	1	2021	2021	NUM
iajs-4030	249	2	;	;	PUNCT
iajs-4030	250	1	398(10302):786–802	398(10302):786–802	NUM
iajs-4030	250	2	.	.	PUNCT
iajs-4030	251	1	https://doi.org/10.1016/s0140-6736(21)00519-5	https://doi.org/10.1016/s0140-6736(21)00519-5	PROPN
iajs-4030	251	2	.	.	PUNCT
iajs-4030	252	1	22	22	NUM
iajs-4030	252	2	.	.	PUNCT
iajs-4030	253	1	wang	wang	PROPN
iajs-4030	253	2	k	k	PROPN
iajs-4030	253	3	,	,	PUNCT
iajs-4030	253	4	liu	liu	PROPN
iajs-4030	253	5	q	q	PROPN
iajs-4030	253	6	,	,	PUNCT
iajs-4030	253	7	tang	tang	PROPN
iajs-4030	253	8	m	m	PROPN
iajs-4030	253	9	,	,	PUNCT
iajs-4030	253	10	qi	qi	PROPN
iajs-4030	253	11	g	g	PROPN
iajs-4030	253	12	,	,	PUNCT
iajs-4030	253	13	qiu	qiu	PROPN
iajs-4030	253	14	c	c	PROPN
iajs-4030	253	15	,	,	PUNCT
iajs-4030	253	16	huang	huang	PROPN
iajs-4030	253	17	y	y	PROPN
iajs-4030	253	18	,	,	PUNCT
iajs-4030	253	19	fang	fang	PROPN
iajs-4030	253	20	x.	x.	PROPN
iajs-4030	253	21	chronic	chronic	PROPN
iajs-4030	253	22	kidney	kidney	PROPN
iajs-4030	253	23	disease‑induced	disease‑induce	VERB
iajs-4030	253	24	muscle	muscle	NOUN
iajs-4030	253	25	atrophy	atrophy	NOUN
iajs-4030	253	26	:	:	PUNCT
iajs-4030	253	27	molecular	molecular	ADJ
iajs-4030	253	28	mechanisms	mechanism	NOUN
iajs-4030	253	29	and	and	CCONJ
iajs-4030	253	30	promising	promise	VERB
iajs-4030	253	31	therapies	therapy	NOUN
iajs-4030	253	32	.	.	PUNCT
iajs-4030	254	1	biochem	biochem	PROPN
iajs-4030	254	2	pharmacol	pharmacol	PROPN
iajs-4030	254	3	.	.	PUNCT
iajs-4030	255	1	2023	2023	NUM
iajs-4030	255	2	;	;	PUNCT
iajs-4030	255	3	208:115407	208:115407	X
iajs-4030	255	4	.	.	PUNCT
iajs-4030	256	1	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	PROPN
iajs-4030	256	2	.	.	PUNCT
iajs-4030	257	1	23	23	NUM
iajs-4030	257	2	.	.	PUNCT
iajs-4030	258	1	mohammed	mohammed	PROPN
iajs-4030	258	2	ms	ms	PROPN
iajs-4030	258	3	,	,	PUNCT
iajs-4030	258	4	ahmed	ahmed	PROPN
iajs-4030	258	5	hs	hs	PROPN
iajs-4030	258	6	.	.	PROPN
iajs-4030	258	7	urokinase‑type	urokinase‑type	ADJ
iajs-4030	258	8	plasminogen	plasminogen	NOUN
iajs-4030	258	9	activator	activator	NOUN
iajs-4030	258	10	receptor	receptor	NOUN
iajs-4030	258	11	as	as	ADP
iajs-4030	258	12	a	a	DET
iajs-4030	258	13	predictive	predictive	ADJ
iajs-4030	258	14	marker	marker	NOUN
iajs-4030	258	15	for	for	ADP
iajs-4030	258	16	cardiac	cardiac	ADJ
iajs-4030	258	17	disease	disease	NOUN
iajs-4030	258	18	among	among	ADP
iajs-4030	258	19	type	type	NOUN
iajs-4030	258	20	 	 	SPACE
iajs-4030	258	21	2	2	NUM
iajs-4030	258	22	diabetic	diabetic	ADJ
iajs-4030	258	23	patients	patient	NOUN
iajs-4030	258	24	.	.	PUNCT
iajs-4030	259	1	med	med	PROPN
iajs-4030	259	2	j	j	PROPN
iajs-4030	259	3	babylon	babylon	PROPN
iajs-4030	259	4	.	.	PUNCT
iajs-4030	260	1	2023	2023	NUM
iajs-4030	260	2	;	;	PUNCT
iajs-4030	261	1	20(4):750–756	20(4):750–756	PROPN
iajs-4030	261	2	.	.	PUNCT
iajs-4030	262	1	https://doi.org/10.4103/mjbl.mjbl_832_23	https://doi.org/10.4103/mjbl.mjbl_832_23	NOUN
iajs-4030	262	2	.	.	PUNCT
iajs-4030	263	1	24	24	NUM
iajs-4030	263	2	.	.	PUNCT
iajs-4030	263	3	raoof	raoof	PROPN
iajs-4030	263	4	emm	emm	PROPN
iajs-4030	263	5	,	,	PUNCT
iajs-4030	263	6	ahmed	ahmed	PROPN
iajs-4030	263	7	hs	hs	PROPN
iajs-4030	263	8	.	.	PROPN
iajs-4030	263	9	circulating	circulate	VERB
iajs-4030	263	10	adipsin	adipsin	PROPN
iajs-4030	263	11	as	as	ADP
iajs-4030	263	12	biomarker	biomarker	NOUN
iajs-4030	263	13	and	and	CCONJ
iajs-4030	263	14	its	its	PRON
iajs-4030	263	15	implication	implication	NOUN
iajs-4030	263	16	in	in	ADP
iajs-4030	263	17	type	type	NOUN
iajs-4030	263	18	 	 	SPACE
iajs-4030	263	19	2	2	NUM
iajs-4030	263	20	diabetes	diabetes	NOUN
iajs-4030	263	21	mellitus	mellitus	NOUN
iajs-4030	263	22	.	.	PUNCT
iajs-4030	264	1	int	int	PROPN
iajs-4030	264	2	j	j	PROPN
iajs-4030	264	3	drug	drug	PROPN
iajs-4030	264	4	deliv	deliv	VERB
iajs-4030	264	5	technol	technol	NOUN
iajs-4030	264	6	.	.	PUNCT
iajs-4030	264	7	2022	2022	NUM
iajs-4030	264	8	;	;	PUNCT
iajs-4030	264	9	12(2):588–593	12(2):588–593	NUM
iajs-4030	264	10	.	.	PUNCT
iajs-4030	265	1	https://doi.org/10.25258/ijddt.12.2.21	https://doi.org/10.25258/ijddt.12.2.21	PROPN
iajs-4030	265	2	.	.	PUNCT
iajs-4030	266	1	25	25	NUM
iajs-4030	266	2	.	.	PUNCT
iajs-4030	267	1	mohammed	mohammed	PROPN
iajs-4030	267	2	ms	ms	PROPN
iajs-4030	267	3	,	,	PUNCT
iajs-4030	267	4	ahmed	ahmed	PROPN
iajs-4030	267	5	hs	hs	PROPN
iajs-4030	267	6	.	.	PROPN
iajs-4030	267	7	atherogenic	atherogenic	ADJ
iajs-4030	267	8	indices	index	NOUN
iajs-4030	267	9	in	in	ADP
iajs-4030	267	10	type	type	NOUN
iajs-4030	267	11	 	 	SPACE
iajs-4030	267	12	2	2	NUM
iajs-4030	267	13	diabetic	diabetic	ADJ
iajs-4030	267	14	iraqi	iraqi	ADJ
iajs-4030	267	15	patients	patient	NOUN
iajs-4030	267	16	and	and	CCONJ
iajs-4030	267	17	its	its	PRON
iajs-4030	267	18	association	association	NOUN
iajs-4030	267	19	with	with	ADP
iajs-4030	267	20	cardiovascular	cardiovascular	ADJ
iajs-4030	267	21	disease	disease	NOUN
iajs-4030	267	22	risk	risk	NOUN
iajs-4030	267	23	.	.	PUNCT
iajs-4030	268	1	j	j	PROPN
iajs-4030	268	2	fac	fac	PROPN
iajs-4030	268	3	med	med	PROPN
iajs-4030	268	4	baghdad	baghdad	PROPN
iajs-4030	268	5	.	.	PUNCT
iajs-4030	269	1	2023	2023	NUM
iajs-4030	269	2	;	;	PUNCT
iajs-4030	270	1	65(3):179–186	65(3):179–186	PROPN
iajs-4030	270	2	.	.	PUNCT
iajs-4030	270	3	https://doi.org/10.32007/jfacmedbagdad.2075	https://doi.org/10.32007/jfacmedbagdad.2075	PROPN
iajs-4030	270	4	.	.	PROPN
iajs-4030	271	1	26	26	NUM
iajs-4030	271	2	.	.	PUNCT
iajs-4030	272	1	lee	lee	PROPN
iajs-4030	272	2	yj	yj	PROPN
iajs-4030	272	3	,	,	PUNCT
iajs-4030	272	4	cho	cho	PROPN
iajs-4030	272	5	s	s	PROPN
iajs-4030	272	6	,	,	PUNCT
iajs-4030	272	7	kim	kim	PROPN
iajs-4030	272	8	sr	sr	PROPN
iajs-4030	272	9	.	.	PUNCT
iajs-4030	273	1	effect	effect	NOUN
iajs-4030	273	2	of	of	ADP
iajs-4030	273	3	alcohol	alcohol	NOUN
iajs-4030	273	4	consumption	consumption	NOUN
iajs-4030	273	5	on	on	ADP
iajs-4030	273	6	kidney	kidney	NOUN
iajs-4030	273	7	function	function	NOUN
iajs-4030	273	8	:	:	PUNCT
iajs-4030	273	9	population‑based	population‑base	VERB
iajs-4030	273	10	cohort	cohort	NOUN
iajs-4030	273	11	study	study	NOUN
iajs-4030	273	12	.	.	PUNCT
iajs-4030	274	1	sci	sci	PROPN
iajs-4030	274	2	rep	rep	PROPN
iajs-4030	274	3	.	.	PROPN
iajs-4030	274	4	2021	2021	NUM
iajs-4030	274	5	;	;	PUNCT
iajs-4030	274	6	11(1):2381	11(1):2381	NUM
iajs-4030	274	7	.	.	PUNCT
iajs-4030	274	8	https://doi.org/10.1038/s41598-021-81777-5	https://doi.org/10.1038/s41598-021-81777-5	NUM
iajs-4030	274	9	.	.	PUNCT
iajs-4030	275	1	27	27	NUM
iajs-4030	275	2	.	.	PUNCT
iajs-4030	276	1	ravid	ravid	PROPN
iajs-4030	276	2	jd	jd	PROPN
iajs-4030	276	3	,	,	PUNCT
iajs-4030	276	4	chitalia	chitalia	PROPN
iajs-4030	276	5	vc	vc	PROPN
iajs-4030	276	6	.	.	PUNCT
iajs-4030	276	7	molecular	molecular	ADJ
iajs-4030	276	8	mechanisms	mechanism	NOUN
iajs-4030	276	9	underlying	underlie	VERB
iajs-4030	276	10	the	the	DET
iajs-4030	276	11	cardiovascular	cardiovascular	ADJ
iajs-4030	276	12	toxicity	toxicity	NOUN
iajs-4030	276	13	of	of	ADP
iajs-4030	276	14	specific	specific	ADJ
iajs-4030	276	15	uremic	uremic	ADJ
iajs-4030	276	16	solutes	solute	NOUN
iajs-4030	276	17	.	.	PUNCT
iajs-4030	276	18	cells	cell	NOUN
iajs-4030	276	19	.	.	PUNCT
iajs-4030	277	1	2020	2020	NUM
iajs-4030	277	2	;	;	PUNCT
iajs-4030	277	3	9(9):2024	9(9):2024	NUM
iajs-4030	277	4	.	.	PUNCT
iajs-4030	277	5	https://doi.org/10.3390/cells9092024	https://doi.org/10.3390/cells9092024	NOUN
iajs-4030	277	6	.	.	PUNCT
iajs-4030	278	1	https://ijrps.com/index.php/home/article/view/599	https://ijrps.com/index.php/home/article/view/599	PRON
iajs-4030	278	2	https://doi.org/10.1016/j.ajpath.2023.01.007	https://doi.org/10.1016/j.ajpath.2023.01.007	VERB
iajs-4030	278	3	https://doi.org/10.3389/fphar.2021.785375	https://doi.org/10.3389/fphar.2021.785375	PROPN
iajs-4030	278	4	https://doi.org/%2010.1038/nrdp.2017.88	https://doi.org/%2010.1038/nrdp.2017.88	PROPN
iajs-4030	278	5	https://doi.org/10.1038/s41581-024-00820-6	https://doi.org/10.1038/s41581-024-00820-6	NUM
iajs-4030	278	6	https://doi.org/%2010.1016/j.ekir.2019.12.001	https://doi.org/%2010.1016/j.ekir.2019.12.001	PROPN
iajs-4030	278	7	.	.	PUNCT
iajs-4030	279	1	https://doi.org/%2010.1016/j.ekir.2019.12.001	https://doi.org/%2010.1016/j.ekir.2019.12.001	PROPN
iajs-4030	279	2	.	.	PUNCT
iajs-4030	280	1	https://doi.org/10.3389/fmed.2022.769329	https://doi.org/10.3389/fmed.2022.769329	PROPN
iajs-4030	280	2	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	PROPN
iajs-4030	280	3	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	PROPN
iajs-4030	280	4	https://doi.org/10.1016/s0140-6736(21)00519-5	https://doi.org/10.1016/s0140-6736(21)00519-5	PROPN
iajs-4030	280	5	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	http://dx.doi.org/10.1016/b978-0-443-15500-0.00003-7	PROPN
iajs-4030	280	6	https://doi.org/10.4103/mjbl.mjbl_832_23	https://doi.org/10.4103/mjbl.mjbl_832_23	PROPN
iajs-4030	280	7	https://doi.org/10.25258/ijddt.12.2.21	https://doi.org/10.25258/ijddt.12.2.21	PROPN
iajs-4030	280	8	https://doi.org/10.32007/jfacmedbagdad.2075	https://doi.org/10.32007/jfacmedbagdad.2075	PROPN
iajs-4030	280	9	https://doi.org/10.1038/s41598-021-81777-5	https://doi.org/10.1038/s41598-021-81777-5	NUM
iajs-4030	280	10	https://doi.org/10.3390/cells9092024	https://doi.org/10.3390/cells9092024	NOUN
iajs-4030	280	11	ihjpas	ihjpa	NOUN
iajs-4030	280	12	.	.	PUNCT
iajs-4030	281	1	38(3)2025	38(3)2025	NUM
iajs-4030	281	2	282	282	NUM
iajs-4030	281	3	28	28	NUM
iajs-4030	281	4	.	.	PUNCT
iajs-4030	282	1	ravid	ravid	PROPN
iajs-4030	282	2	jd	jd	PROPN
iajs-4030	282	3	,	,	PUNCT
iajs-4030	282	4	kamel	kamel	PROPN
iajs-4030	282	5	mh	mh	PROPN
iajs-4030	282	6	,	,	PUNCT
iajs-4030	282	7	chitalia	chitalia	PROPN
iajs-4030	282	8	vc	vc	PROPN
iajs-4030	282	9	.	.	PUNCT
iajs-4030	283	1	uraemic	uraemic	ADJ
iajs-4030	283	2	solutes	solute	NOUN
iajs-4030	283	3	as	as	ADP
iajs-4030	283	4	therapeutic	therapeutic	ADJ
iajs-4030	283	5	targets	target	NOUN
iajs-4030	283	6	in	in	ADP
iajs-4030	283	7	ckd‑associated	ckd‑associate	VERB
iajs-4030	283	8	cardiovascular	cardiovascular	ADJ
iajs-4030	283	9	disease	disease	NOUN
iajs-4030	283	10	.	.	PUNCT
iajs-4030	284	1	nat	nat	PROPN
iajs-4030	284	2	rev	rev	VERB
iajs-4030	284	3	nephrol	nephrol	NOUN
iajs-4030	284	4	.	.	PUNCT
iajs-4030	284	5	2021	2021	NUM
iajs-4030	284	6	;	;	PUNCT
iajs-4030	284	7	17(6):402–416	17(6):402–416	NUM
iajs-4030	284	8	.	.	PUNCT
iajs-4030	285	1	https://doi.org/10.1038/s41581021-00408-4	https://doi.org/10.1038/s41581021-00408-4	NOUN
iajs-4030	285	2	.	.	PUNCT
iajs-4030	286	1	29	29	NUM
iajs-4030	286	2	.	.	PUNCT
iajs-4030	287	1	adeyomoye	adeyomoye	NOUN
iajs-4030	287	2	oi	oi	PROPN
iajs-4030	287	3	,	,	PUNCT
iajs-4030	287	4	akintayo	akintayo	NOUN
iajs-4030	287	5	co	co	NOUN
iajs-4030	287	6	,	,	PUNCT
iajs-4030	287	7	omotuyi	omotuyi	NOUN
iajs-4030	287	8	kp	kp	PROPN
iajs-4030	287	9	,	,	PUNCT
iajs-4030	287	10	adewumi	adewumi	PROPN
iajs-4030	287	11	an	an	PROPN
iajs-4030	287	12	.	.	PUNCT
iajs-4030	288	1	the	the	DET
iajs-4030	288	2	biological	biological	ADJ
iajs-4030	288	3	roles	role	NOUN
iajs-4030	288	4	of	of	ADP
iajs-4030	288	5	urea	urea	NOUN
iajs-4030	288	6	:	:	PUNCT
iajs-4030	288	7	a	a	DET
iajs-4030	288	8	review	review	NOUN
iajs-4030	288	9	of	of	ADP
iajs-4030	288	10	preclinical	preclinical	ADJ
iajs-4030	288	11	studies	study	NOUN
iajs-4030	288	12	.	.	PUNCT
iajs-4030	289	1	indian	indian	PROPN
iajs-4030	289	2	j	j	PROPN
iajs-4030	289	3	nephrol	nephrol	NOUN
iajs-4030	289	4	.	.	PUNCT
iajs-4030	290	1	2022	2022	NUM
iajs-4030	290	2	;	;	PUNCT
iajs-4030	291	1	32(6):539–545	32(6):539–545	NUM
iajs-4030	291	2	.	.	PUNCT
iajs-4030	292	1	https://doi.org/10.4103%2fijn.ijn_88_21	https://doi.org/10.4103%2fijn.ijn_88_21	ADJ
iajs-4030	292	2	.	.	PUNCT
iajs-4030	293	1	30	30	NUM
iajs-4030	293	2	.	.	PUNCT
iajs-4030	294	1	tahir	tahir	PROPN
iajs-4030	294	2	nt	nt	PROPN
iajs-4030	294	3	,	,	PUNCT
iajs-4030	294	4	ahmed	ahmed	PROPN
iajs-4030	294	5	hs	hs	PROPN
iajs-4030	294	6	,	,	PUNCT
iajs-4030	294	7	mohsen	mohsen	PROPN
iajs-4030	294	8	fy	fy	PROPN
iajs-4030	294	9	.	.	PUNCT
iajs-4030	294	10	vitamin	vitamin	PROPN
iajs-4030	294	11	d	d	NOUN
iajs-4030	294	12	and	and	CCONJ
iajs-4030	294	13	risk	risk	NOUN
iajs-4030	294	14	of	of	ADP
iajs-4030	294	15	osteoarthritis	osteoarthritis	NOUN
iajs-4030	294	16	among	among	ADP
iajs-4030	294	17	iraqi	iraqi	ADJ
iajs-4030	294	18	patients	patient	NOUN
iajs-4030	294	19	with	with	ADP
iajs-4030	294	20	and	and	CCONJ
iajs-4030	294	21	without	without	ADP
iajs-4030	294	22	metabolic	metabolic	NOUN
iajs-4030	294	23	syndrome	syndrome	NOUN
iajs-4030	294	24	.	.	PUNCT
iajs-4030	295	1	plant	plant	NOUN
iajs-4030	295	2	arch	arch	NOUN
iajs-4030	295	3	.	.	PUNCT
iajs-4030	296	1	2020	2020	NUM
iajs-4030	296	2	;	;	PUNCT
iajs-4030	296	3	20:2731–2736	20:2731–2736	NUM
iajs-4030	296	4	.	.	PUNCT
iajs-4030	297	1	31	31	NUM
iajs-4030	297	2	.	.	PUNCT
iajs-4030	298	1	lew	lew	PROPN
iajs-4030	298	2	sq	sq	PROPN
iajs-4030	298	3	,	,	PUNCT
iajs-4030	298	4	radhakrishnan	radhakrishnan	PROPN
iajs-4030	298	5	j.	j.	PROPN
iajs-4030	298	6	chronic	chronic	PROPN
iajs-4030	298	7	kidney	kidney	NOUN
iajs-4030	298	8	disease	disease	NOUN
iajs-4030	298	9	and	and	CCONJ
iajs-4030	298	10	gastrointestinal	gastrointestinal	ADJ
iajs-4030	298	11	disorders	disorder	NOUN
iajs-4030	298	12	.	.	PUNCT
iajs-4030	299	1	in	in	ADP
iajs-4030	299	2	:	:	PUNCT
iajs-4030	299	3	chronic	chronic	ADJ
iajs-4030	299	4	renal	renal	ADJ
iajs-4030	299	5	disease	disease	NOUN
iajs-4030	299	6	.	.	PUNCT
iajs-4030	300	1	2020:521–539	2020:521–539	X
iajs-4030	300	2	.	.	PUNCT
iajs-4030	301	1	https://doi.org/10.1016/b978-0-12-411602-3.00025-1	https://doi.org/10.1016/b978-0-12-411602-3.00025-1	NOUN
iajs-4030	301	2	.	.	PUNCT
iajs-4030	302	1	32	32	NUM
iajs-4030	302	2	.	.	PUNCT
iajs-4030	303	1	laville	laville	PROPN
iajs-4030	303	2	sm	sm	PROPN
iajs-4030	303	3	,	,	PUNCT
iajs-4030	303	4	couturier	couturier	PROPN
iajs-4030	303	5	a	a	PROPN
iajs-4030	303	6	,	,	PUNCT
iajs-4030	303	7	lambert	lambert	PROPN
iajs-4030	303	8	o	o	PROPN
iajs-4030	303	9	,	,	PUNCT
iajs-4030	303	10	metzger	metzger	PROPN
iajs-4030	303	11	m	m	PROPN
iajs-4030	303	12	,	,	PUNCT
iajs-4030	303	13	mansencal	mansencal	ADJ
iajs-4030	303	14	n	n	CCONJ
iajs-4030	303	15	,	,	PUNCT
iajs-4030	303	16	jacquelinet	jacquelinet	NOUN
iajs-4030	303	17	c	c	NOUN
iajs-4030	303	18	,	,	PUNCT
iajs-4030	303	19	massy	massy	PROPN
iajs-4030	303	20	za	za	PROPN
iajs-4030	303	21	.	.	PROPN
iajs-4030	303	22	urea	urea	PROPN
iajs-4030	303	23	levels	level	NOUN
iajs-4030	303	24	and	and	CCONJ
iajs-4030	303	25	cardiovascular	cardiovascular	ADJ
iajs-4030	303	26	disease	disease	NOUN
iajs-4030	303	27	in	in	ADP
iajs-4030	303	28	patients	patient	NOUN
iajs-4030	303	29	with	with	ADP
iajs-4030	303	30	chronic	chronic	ADJ
iajs-4030	303	31	kidney	kidney	NOUN
iajs-4030	303	32	disease	disease	NOUN
iajs-4030	303	33	.	.	PUNCT
iajs-4030	304	1	nephrol	nephrol	PROPN
iajs-4030	304	2	dial	dial	NOUN
iajs-4030	304	3	transpl	transpl	NOUN
iajs-4030	304	4	.	.	PUNCT
iajs-4030	305	1	2023	2023	NUM
iajs-4030	305	2	;	;	PUNCT
iajs-4030	305	3	38(1):184–192	38(1):184–192	NUM
iajs-4030	305	4	.	.	PUNCT
iajs-4030	306	1	https://doi.org/10.1093/ndt/gfac045	https://doi.org/10.1093/ndt/gfac045	NOUN
iajs-4030	306	2	.	.	PROPN
iajs-4030	307	1	33	33	NUM
iajs-4030	307	2	.	.	PUNCT
iajs-4030	308	1	yanai	yanai	PROPN
iajs-4030	308	2	h	h	PROPN
iajs-4030	308	3	,	,	PUNCT
iajs-4030	308	4	adachi	adachi	PROPN
iajs-4030	308	5	h	h	PROPN
iajs-4030	308	6	,	,	PUNCT
iajs-4030	308	7	hakoshima	hakoshima	PROPN
iajs-4030	308	8	m	m	PROPN
iajs-4030	308	9	,	,	PUNCT
iajs-4030	308	10	katsuyama	katsuyama	PROPN
iajs-4030	308	11	h.	h.	PROPN
iajs-4030	308	12	molecular	molecular	ADJ
iajs-4030	308	13	biological	biological	ADJ
iajs-4030	308	14	and	and	CCONJ
iajs-4030	308	15	clinical	clinical	ADJ
iajs-4030	308	16	understanding	understanding	NOUN
iajs-4030	308	17	of	of	ADP
iajs-4030	308	18	the	the	DET
iajs-4030	308	19	pathophysiology	pathophysiology	NOUN
iajs-4030	308	20	and	and	CCONJ
iajs-4030	308	21	treatments	treatment	NOUN
iajs-4030	308	22	of	of	ADP
iajs-4030	308	23	hyperuricemia	hyperuricemia	NOUN
iajs-4030	308	24	and	and	CCONJ
iajs-4030	308	25	its	its	PRON
iajs-4030	308	26	association	association	NOUN
iajs-4030	308	27	with	with	ADP
iajs-4030	308	28	metabolic	metabolic	NOUN
iajs-4030	308	29	syndrome	syndrome	NOUN
iajs-4030	308	30	,	,	PUNCT
iajs-4030	308	31	cardiovascular	cardiovascular	ADJ
iajs-4030	308	32	diseases	disease	NOUN
iajs-4030	308	33	and	and	CCONJ
iajs-4030	308	34	chronic	chronic	ADJ
iajs-4030	308	35	kidney	kidney	NOUN
iajs-4030	308	36	disease	disease	NOUN
iajs-4030	308	37	.	.	PUNCT
iajs-4030	309	1	int	int	PROPN
iajs-4030	309	2	j	j	PROPN
iajs-4030	309	3	mol	mol	ADP
iajs-4030	309	4	sci	sci	PROPN
iajs-4030	309	5	.	.	PROPN
iajs-4030	309	6	2021	2021	NUM
iajs-4030	309	7	;	;	PUNCT
iajs-4030	309	8	22(17):9221	22(17):9221	NUM
iajs-4030	309	9	.	.	PUNCT
iajs-4030	310	1	https://doi.org/10.3390/ijms22179221	https://doi.org/10.3390/ijms22179221	PROPN
iajs-4030	310	2	.	.	PUNCT
iajs-4030	311	1	34	34	NUM
iajs-4030	311	2	.	.	PUNCT
iajs-4030	312	1	zsom	zsom	PROPN
iajs-4030	312	2	l	l	NOUN
iajs-4030	312	3	,	,	PUNCT
iajs-4030	312	4	zsom	zsom	PROPN
iajs-4030	312	5	m	m	PROPN
iajs-4030	312	6	,	,	PUNCT
iajs-4030	312	7	salim	salim	PROPN
iajs-4030	312	8	sa	sa	PROPN
iajs-4030	312	9	,	,	PUNCT
iajs-4030	312	10	fulop	fulop	PROPN
iajs-4030	312	11	t.	t.	PROPN
iajs-4030	312	12	estimated	estimate	VERB
iajs-4030	312	13	glomerular	glomerular	ADJ
iajs-4030	312	14	filtration	filtration	NOUN
iajs-4030	312	15	rate	rate	NOUN
iajs-4030	312	16	in	in	ADP
iajs-4030	312	17	chronic	chronic	ADJ
iajs-4030	312	18	kidney	kidney	NOUN
iajs-4030	312	19	disease	disease	NOUN
iajs-4030	312	20	:	:	PUNCT
iajs-4030	312	21	a	a	DET
iajs-4030	312	22	critical	critical	ADJ
iajs-4030	312	23	review	review	NOUN
iajs-4030	312	24	of	of	ADP
iajs-4030	312	25	estimate‑based	estimate‑base	VERB
iajs-4030	312	26	predictions	prediction	NOUN
iajs-4030	312	27	of	of	ADP
iajs-4030	312	28	individual	individual	ADJ
iajs-4030	312	29	outcomes	outcome	NOUN
iajs-4030	312	30	in	in	ADP
iajs-4030	312	31	kidney	kidney	NOUN
iajs-4030	312	32	disease	disease	NOUN
iajs-4030	312	33	.	.	PUNCT
iajs-4030	313	1	toxins	toxin	NOUN
iajs-4030	313	2	.	.	PUNCT
iajs-4030	314	1	2022	2022	NUM
iajs-4030	314	2	;	;	PUNCT
iajs-4030	314	3	14(2):127	14(2):127	NUM
iajs-4030	314	4	.	.	PUNCT
iajs-4030	315	1	https://doi.org/10.3390/toxins14020127	https://doi.org/10.3390/toxins14020127	NOUN
iajs-4030	315	2	.	.	PUNCT
iajs-4030	316	1	35	35	NUM
iajs-4030	316	2	.	.	PUNCT
iajs-4030	317	1	ahmed	ahmed	PROPN
iajs-4030	317	2	hsh	hsh	PROPN
iajs-4030	317	3	,	,	PUNCT
iajs-4030	317	4	abbas	abbas	PROPN
iajs-4030	317	5	ak	ak	PROPN
iajs-4030	317	6	.	.	PROPN
iajs-4030	318	1	the	the	DET
iajs-4030	318	2	relationship	relationship	NOUN
iajs-4030	318	3	between	between	ADP
iajs-4030	318	4	reproductive	reproductive	ADJ
iajs-4030	318	5	hormones	hormone	NOUN
iajs-4030	318	6	and	and	CCONJ
iajs-4030	318	7	metabolic	metabolic	NOUN
iajs-4030	318	8	parameters	parameter	NOUN
iajs-4030	318	9	in	in	ADP
iajs-4030	318	10	women	woman	NOUN
iajs-4030	318	11	with	with	ADP
iajs-4030	318	12	polycystic	polycystic	ADJ
iajs-4030	318	13	ovary	ovary	ADJ
iajs-4030	318	14	syndrome	syndrome	NOUN
iajs-4030	318	15	.	.	PUNCT
iajs-4030	319	1	j	j	PROPN
iajs-4030	319	2	fac	fac	PROPN
iajs-4030	319	3	med	med	PROPN
iajs-4030	319	4	baghdad	baghdad	PROPN
iajs-4030	319	5	.	.	PUNCT
iajs-4030	320	1	2014	2014	NUM
iajs-4030	320	2	;	;	PUNCT
iajs-4030	321	1	56(2):234–238	56(2):234–238	NUM
iajs-4030	321	2	.	.	PUNCT
iajs-4030	322	1	https://doi.org/10.32007/jfacmedbagdad.562483	https://doi.org/10.32007/jfacmedbagdad.562483	NOUN
iajs-4030	322	2	.	.	PUNCT
iajs-4030	323	1	36	36	NUM
iajs-4030	323	2	.	.	PUNCT
iajs-4030	324	1	kahraman	kahraman	PROPN
iajs-4030	324	2	zb	zb	PROPN
iajs-4030	324	3	,	,	PUNCT
iajs-4030	324	4	dizdar	dizdar	NOUN
iajs-4030	324	5	os	os	PROPN
iajs-4030	324	6	,	,	PUNCT
iajs-4030	324	7	guna	guna	PROPN
iajs-4030	324	8	ai	ai	VERB
iajs-4030	324	9	.	.	PUNCT
iajs-4030	325	1	the	the	DET
iajs-4030	325	2	effect	effect	NOUN
iajs-4030	325	3	of	of	ADP
iajs-4030	325	4	hypervolemia	hypervolemia	PROPN
iajs-4030	325	5	control	control	PROPN
iajs-4030	325	6	on	on	ADP
iajs-4030	325	7	proteinuria	proteinuria	NOUN
iajs-4030	325	8	in	in	ADP
iajs-4030	325	9	kidney	kidney	NOUN
iajs-4030	325	10	disease	disease	NOUN
iajs-4030	325	11	:	:	PUNCT
iajs-4030	325	12	a	a	DET
iajs-4030	325	13	prospective	prospective	ADJ
iajs-4030	325	14	interventional	interventional	ADJ
iajs-4030	325	15	study	study	NOUN
iajs-4030	325	16	.	.	PUNCT
iajs-4030	326	1	j	j	PROPN
iajs-4030	326	2	clin	clin	PROPN
iajs-4030	326	3	pract	pract	PROPN
iajs-4030	326	4	res	re	NOUN
iajs-4030	326	5	.	.	PUNCT
iajs-4030	326	6	2024	2024	NUM
iajs-4030	326	7	;	;	PUNCT
iajs-4030	326	8	46(3):234–241	46(3):234–241	PROPN
iajs-4030	326	9	.	.	PUNCT
iajs-4030	326	10	https://doi.org/	https://doi.org/	VERB
iajs-4030	326	11	10.14744	10.14744	NUM
iajs-4030	326	12	/	/	SYM
iajs-4030	326	13	cpr.2024.92387	cpr.2024.92387	NOUN
iajs-4030	326	14	.	.	PROPN
iajs-4030	326	15	37	37	NUM
iajs-4030	326	16	.	.	PUNCT
iajs-4030	327	1	ahmed	ahmed	PROPN
iajs-4030	327	2	hs	hs	PROPN
iajs-4030	327	3	,	,	PUNCT
iajs-4030	327	4	ahmed	ahmed	PROPN
iajs-4030	327	5	hs	hs	PROPN
iajs-4030	327	6	,	,	PUNCT
iajs-4030	327	7	ad’hiah	ad’hiah	PROPN
iajs-4030	327	8	ah	ah	INTJ
iajs-4030	327	9	.	.	PUNCT
iajs-4030	328	1	interleukin‑1	interleukin‑1	PROPN
iajs-4030	328	2	single	single	ADJ
iajs-4030	328	3	nucleotide	nucleotide	ADJ
iajs-4030	328	4	polymorphisms	polymorphism	NOUN
iajs-4030	328	5	and	and	CCONJ
iajs-4030	328	6	risk	risk	NOUN
iajs-4030	328	7	of	of	ADP
iajs-4030	328	8	systemic	systemic	ADJ
iajs-4030	328	9	lupus	lupus	NOUN
iajs-4030	328	10	erythematosus	erythematosus	NOUN
iajs-4030	328	11	among	among	ADP
iajs-4030	328	12	iraqi	iraqi	ADJ
iajs-4030	328	13	patients	patient	NOUN
iajs-4030	328	14	.	.	PUNCT
iajs-4030	329	1	meta	meta	PROPN
iajs-4030	329	2	gene	gene	NOUN
iajs-4030	329	3	.	.	PUNCT
iajs-4030	330	1	2020	2020	NUM
iajs-4030	330	2	;	;	PUNCT
iajs-4030	330	3	23:100640	23:100640	NUM
iajs-4030	330	4	.	.	PUNCT
iajs-4030	331	1	http://dx.doi.org/10.1016/j.mgene.2019.100640	http://dx.doi.org/10.1016/j.mgene.2019.100640	NUM
iajs-4030	331	2	.	.	PUNCT
iajs-4030	332	1	38	38	NUM
iajs-4030	332	2	.	.	PUNCT
iajs-4030	333	1	vallés‑saiz	vallés‑saiz	PROPN
iajs-4030	333	2	l	l	NOUN
iajs-4030	333	3	,	,	PUNCT
iajs-4030	333	4	peinado‑cahuchola	peinado‑cahuchola	PROPN
iajs-4030	333	5	r	r	NOUN
iajs-4030	333	6	,	,	PUNCT
iajs-4030	333	7	ávila	ávila	PROPN
iajs-4030	333	8	j	j	PROPN
iajs-4030	333	9	,	,	PUNCT
iajs-4030	333	10	hernández	hernández	PROPN
iajs-4030	333	11	f.	f.	PROPN
iajs-4030	333	12	microtubule‑associated	microtubule‑associate	VERB
iajs-4030	333	13	protein	protein	NOUN
iajs-4030	333	14	tau	tau	PROPN
iajs-4030	333	15	in	in	ADP
iajs-4030	333	16	murine	murine	ADJ
iajs-4030	333	17	kidney	kidney	NOUN
iajs-4030	333	18	:	:	PUNCT
iajs-4030	333	19	role	role	NOUN
iajs-4030	333	20	in	in	ADP
iajs-4030	333	21	podocyte	podocyte	NOUN
iajs-4030	333	22	architecture	architecture	NOUN
iajs-4030	333	23	.	.	PUNCT
iajs-4030	334	1	cell	cell	NOUN
iajs-4030	334	2	mol	mol	ADP
iajs-4030	334	3	life	life	PROPN
iajs-4030	334	4	sci	sci	PROPN
iajs-4030	334	5	.	.	PROPN
iajs-4030	334	6	2022	2022	NUM
iajs-4030	334	7	;	;	PUNCT
iajs-4030	335	1	79(2):97	79(2):97	NUM
iajs-4030	335	2	.	.	PUNCT
iajs-4030	336	1	https://doi.org/10.1007/s00018-021-04106-z	https://doi.org/10.1007/s00018-021-04106-z	NOUN
iajs-4030	336	2	.	.	PUNCT
iajs-4030	337	1	39	39	NUM
iajs-4030	337	2	.	.	PUNCT
iajs-4030	338	1	li	li	PROPN
iajs-4030	338	2	l	l	PROPN
iajs-4030	338	3	,	,	PUNCT
iajs-4030	338	4	feng	feng	PROPN
iajs-4030	338	5	y	y	PROPN
iajs-4030	338	6	,	,	PUNCT
iajs-4030	338	7	zhang	zhang	PROPN
iajs-4030	338	8	j	j	PROPN
iajs-4030	338	9	,	,	PUNCT
iajs-4030	338	10	zhang	zhang	PROPN
iajs-4030	338	11	q	q	PROPN
iajs-4030	338	12	,	,	PUNCT
iajs-4030	338	13	ren	ren	PROPN
iajs-4030	338	14	j	j	PROPN
iajs-4030	338	15	,	,	PUNCT
iajs-4030	338	16	sun	sun	PROPN
iajs-4030	338	17	c	c	PROPN
iajs-4030	338	18	,	,	PUNCT
iajs-4030	338	19	li	li	PROPN
iajs-4030	338	20	sh	sh	PROPN
iajs-4030	338	21	,	,	PUNCT
iajs-4030	338	22	lei	lei	X
iajs-4030	338	23	x	x	PROPN
iajs-4030	338	24	,	,	PUNCT
iajs-4030	338	25	luo	luo	PROPN
iajs-4030	338	26	g	g	PROPN
iajs-4030	338	27	,	,	PUNCT
iajs-4030	338	28	hu	hu	PROPN
iajs-4030	338	29	j	j	PROPN
iajs-4030	338	30	,	,	PUNCT
iajs-4030	338	31	huang	huang	PROPN
iajs-4030	338	32	y.	y.	PROPN
iajs-4030	338	33	microtubule	microtubule	PROPN
iajs-4030	338	34	associated	associate	VERB
iajs-4030	338	35	protein	protein	NOUN
iajs-4030	338	36	4	4	NUM
iajs-4030	338	37	phosphorylation‑induced	phosphorylation‑induce	VERB
iajs-4030	338	38	epithelial‑to‑mesenchymal	epithelial‑to‑mesenchymal	ADJ
iajs-4030	338	39	transition	transition	NOUN
iajs-4030	338	40	of	of	ADP
iajs-4030	338	41	podocyte	podocyte	NOUN
iajs-4030	338	42	leads	lead	VERB
iajs-4030	338	43	to	to	ADP
iajs-4030	338	44	proteinuria	proteinuria	NOUN
iajs-4030	338	45	in	in	ADP
iajs-4030	338	46	diabetic	diabetic	ADJ
iajs-4030	338	47	nephropathy	nephropathy	NOUN
iajs-4030	338	48	.	.	PUNCT
iajs-4030	339	1	cell	cell	NOUN
iajs-4030	339	2	commun	commun	PROPN
iajs-4030	339	3	signal	signal	PROPN
iajs-4030	339	4	.	.	PUNCT
iajs-4030	340	1	2022	2022	NUM
iajs-4030	340	2	;	;	PUNCT
iajs-4030	341	1	20(1):115	20(1):115	NUM
iajs-4030	341	2	.	.	PUNCT
iajs-4030	342	1	https://doi.org/10.1186/s12964-022-00883-7	https://doi.org/10.1186/s12964-022-00883-7	NUM
iajs-4030	342	2	.	.	PUNCT
iajs-4030	343	1	40	40	NUM
iajs-4030	343	2	.	.	PUNCT
iajs-4030	344	1	daehn	daehn	VERB
iajs-4030	344	2	i	i	PRON
iajs-4030	344	3	,	,	PUNCT
iajs-4030	344	4	casalena	casalena	PROPN
iajs-4030	344	5	g	g	PROPN
iajs-4030	344	6	,	,	PUNCT
iajs-4030	344	7	zhang	zhang	PROPN
iajs-4030	344	8	t	t	PROPN
iajs-4030	344	9	,	,	PUNCT
iajs-4030	344	10	shi	shi	PROPN
iajs-4030	344	11	s	s	PROPN
iajs-4030	344	12	,	,	PUNCT
iajs-4030	344	13	fenninger	fenninger	NOUN
iajs-4030	344	14	f	f	NOUN
iajs-4030	344	15	,	,	PUNCT
iajs-4030	344	16	barasch	barasch	PROPN
iajs-4030	344	17	n	n	CCONJ
iajs-4030	344	18	,	,	PUNCT
iajs-4030	344	19	yu	yu	PROPN
iajs-4030	344	20	l	l	PROPN
iajs-4030	344	21	,	,	PUNCT
iajs-4030	344	22	d’agati	d’agati	PROPN
iajs-4030	344	23	v	v	NOUN
iajs-4030	344	24	,	,	PUNCT
iajs-4030	344	25	schlondorff	schlondorff	PROPN
iajs-4030	344	26	d	d	PROPN
iajs-4030	344	27	,	,	PUNCT
iajs-4030	344	28	kriz	kriz	PROPN
iajs-4030	344	29	w	w	PROPN
iajs-4030	344	30	,	,	PUNCT
iajs-4030	344	31	haraldsson	haraldsson	NOUN
iajs-4030	344	32	b	b	NOUN
iajs-4030	344	33	,	,	PUNCT
iajs-4030	344	34	bottinger	bottinger	PROPN
iajs-4030	344	35	ep	ep	PROPN
iajs-4030	344	36	.	.	PUNCT
iajs-4030	345	1	endothelial	endothelial	ADJ
iajs-4030	345	2	mitochondrial	mitochondrial	ADJ
iajs-4030	345	3	oxidative	oxidative	ADJ
iajs-4030	345	4	stress	stress	NOUN
iajs-4030	345	5	determines	determine	VERB
iajs-4030	345	6	podocyte	podocyte	NOUN
iajs-4030	345	7	depletion	depletion	NOUN
iajs-4030	345	8	in	in	ADP
iajs-4030	345	9	segmental	segmental	ADJ
iajs-4030	345	10	glomerulosclerosis	glomerulosclerosis	NOUN
iajs-4030	345	11	.	.	PUNCT
iajs-4030	346	1	j	j	PROPN
iajs-4030	346	2	clin	clin	PROPN
iajs-4030	346	3	invest	invest	PROPN
iajs-4030	346	4	.	.	PUNCT
iajs-4030	347	1	2014	2014	NUM
iajs-4030	347	2	;	;	PUNCT
iajs-4030	347	3	124(4):1608–1621	124(4):1608–1621	NUM
iajs-4030	347	4	.	.	PUNCT
iajs-4030	348	1	https://doi.org/10.1172/jci71195	https://doi.org/10.1172/jci71195	PROPN
iajs-4030	348	2	.	.	PROPN
iajs-4030	348	3	41	41	NUM
iajs-4030	348	4	.	.	PUNCT
iajs-4030	348	5	hanna	hanna	PROPN
iajs-4030	348	6	rm	rm	PROPN
iajs-4030	348	7	,	,	PUNCT
iajs-4030	348	8	ghobry	ghobry	PROPN
iajs-4030	348	9	l	l	PROPN
iajs-4030	348	10	,	,	PUNCT
iajs-4030	348	11	wassef	wassef	PROPN
iajs-4030	348	12	o	o	PROPN
iajs-4030	348	13	,	,	PUNCT
iajs-4030	348	14	rhee	rhee	PROPN
iajs-4030	348	15	cm	cm	PROPN
iajs-4030	348	16	,	,	PUNCT
iajs-4030	348	17	kalantar‑zadeh	kalantar‑zadeh	PROPN
iajs-4030	348	18	k.	k.	PROPN
iajs-4030	349	1	a	a	DET
iajs-4030	349	2	practical	practical	ADJ
iajs-4030	349	3	approach	approach	NOUN
iajs-4030	349	4	to	to	ADP
iajs-4030	349	5	nutrition	nutrition	NOUN
iajs-4030	349	6	,	,	PUNCT
iajs-4030	349	7	protein‑energy	protein‑energy	PROPN
iajs-4030	349	8	wasting	wasting	NOUN
iajs-4030	349	9	,	,	PUNCT
iajs-4030	349	10	sarcopenia	sarcopenia	NOUN
iajs-4030	349	11	,	,	PUNCT
iajs-4030	349	12	and	and	CCONJ
iajs-4030	349	13	cachexia	cachexia	NOUN
iajs-4030	349	14	in	in	ADP
iajs-4030	349	15	patients	patient	NOUN
iajs-4030	349	16	with	with	ADP
iajs-4030	349	17	chronic	chronic	ADJ
iajs-4030	349	18	kidney	kidney	NOUN
iajs-4030	349	19	disease	disease	NOUN
iajs-4030	349	20	.	.	PUNCT
iajs-4030	350	1	blood	blood	NOUN
iajs-4030	350	2	purif	purif	PROPN
iajs-4030	350	3	.	.	PUNCT
iajs-4030	351	1	2020	2020	NUM
iajs-4030	351	2	;	;	PUNCT
iajs-4030	351	3	49(1–2):202–211	49(1–2):202–211	NUM
iajs-4030	351	4	.	.	PUNCT
iajs-4030	352	1	https://doi.org/10.1159/000504240	https://doi.org/10.1159/000504240	NOUN
iajs-4030	352	2	.	.	PUNCT
iajs-4030	353	1	42	42	NUM
iajs-4030	353	2	.	.	PUNCT
iajs-4030	354	1	drawz	drawz	PROPN
iajs-4030	354	2	p	p	NOUN
iajs-4030	354	3	,	,	PUNCT
iajs-4030	354	4	hostetter	hostetter	NOUN
iajs-4030	354	5	th	th	PROPN
iajs-4030	354	6	,	,	PUNCT
iajs-4030	354	7	rosenberg	rosenberg	PROPN
iajs-4030	354	8	me	i	PRON
iajs-4030	354	9	.	.	PUNCT
iajs-4030	355	1	slowing	slow	VERB
iajs-4030	355	2	progression	progression	NOUN
iajs-4030	355	3	of	of	ADP
iajs-4030	355	4	chronic	chronic	ADJ
iajs-4030	355	5	kidney	kidney	NOUN
iajs-4030	355	6	disease	disease	NOUN
iajs-4030	355	7	.	.	PUNCT
iajs-4030	356	1	in	in	ADP
iajs-4030	356	2	:	:	PUNCT
iajs-4030	356	3	chronic	chronic	ADJ
iajs-4030	356	4	renal	renal	ADJ
iajs-4030	356	5	disease	disease	NOUN
iajs-4030	356	6	.	.	PUNCT
iajs-4030	357	1	academic	academic	ADJ
iajs-4030	357	2	press	press	NOUN
iajs-4030	357	3	;	;	PUNCT
iajs-4030	357	4	2020	2020	NUM
iajs-4030	357	5	;	;	PUNCT
iajs-4030	357	6	p.	p.	NOUN
iajs-4030	357	7	 	 	SPACE
iajs-4030	357	8	937–959	937–959	NUM
iajs-4030	357	9	.	.	PUNCT
iajs-4030	358	1	https://doi.org/10.1016/b978-0-12815876-0.00057-7	https://doi.org/10.1016/b978-0-12815876-0.00057-7	NOUN
iajs-4030	358	2	.	.	PUNCT
iajs-4030	359	1	43	43	NUM
iajs-4030	359	2	.	.	PUNCT
iajs-4030	360	1	dai	dai	PROPN
iajs-4030	360	2	c	c	PROPN
iajs-4030	360	3	,	,	PUNCT
iajs-4030	360	4	stolz	stolz	PROPN
iajs-4030	360	5	db	db	PROPN
iajs-4030	360	6	,	,	PUNCT
iajs-4030	360	7	bastacky	bastacky	PROPN
iajs-4030	360	8	si	si	NOUN
iajs-4030	360	9	,	,	PUNCT
iajs-4030	360	10	st‑arnaud	st‑arnaud	NOUN
iajs-4030	360	11	r	r	NOUN
iajs-4030	360	12	,	,	PUNCT
iajs-4030	360	13	wu	wu	PROPN
iajs-4030	360	14	c	c	NOUN
iajs-4030	360	15	,	,	PUNCT
iajs-4030	360	16	dedhar	dedhar	PROPN
iajs-4030	360	17	s	s	PROPN
iajs-4030	360	18	,	,	PUNCT
iajs-4030	360	19	liu	liu	PROPN
iajs-4030	360	20	y.	y.	PROPN
iajs-4030	360	21	essential	essential	ADJ
iajs-4030	360	22	role	role	NOUN
iajs-4030	360	23	of	of	ADP
iajs-4030	360	24	integrin‑	integrin‑	NOUN
iajs-4030	360	25	linked	link	VERB
iajs-4030	360	26	kinase	kinase	NOUN
iajs-4030	360	27	in	in	ADP
iajs-4030	360	28	podocyte	podocyte	NOUN
iajs-4030	360	29	biology	biology	NOUN
iajs-4030	360	30	:	:	PUNCT
iajs-4030	360	31	bridging	bridge	VERB
iajs-4030	360	32	the	the	DET
iajs-4030	360	33	integrin	integrin	NOUN
iajs-4030	360	34	and	and	CCONJ
iajs-4030	360	35	slit	slit	ADJ
iajs-4030	360	36	diaphragm	diaphragm	NOUN
iajs-4030	360	37	signaling	signal	VERB
iajs-4030	360	38	.	.	PUNCT
iajs-4030	361	1	j	j	PROPN
iajs-4030	361	2	am	be	AUX
iajs-4030	361	3	soc	soc	NOUN
iajs-4030	361	4	nephrol	nephrol	NOUN
iajs-4030	361	5	.	.	PUNCT
iajs-4030	362	1	2006	2006	NUM
iajs-4030	362	2	;	;	PUNCT
iajs-4030	362	3	17(8):2164–2175	17(8):2164–2175	NUM
iajs-4030	362	4	.	.	PUNCT
iajs-4030	363	1	https://doi.org/10.1681/asn.2006010033	https://doi.org/10.1681/asn.2006010033	PROPN
iajs-4030	363	2	.	.	PROPN
iajs-4030	363	3	44	44	NUM
iajs-4030	363	4	.	.	PUNCT
iajs-4030	364	1	kumar	kumar	PROPN
iajs-4030	364	2	pa	pa	PROPN
iajs-4030	364	3	,	,	PUNCT
iajs-4030	364	4	welsh	welsh	PROPN
iajs-4030	364	5	gi	gi	PROPN
iajs-4030	364	6	,	,	PUNCT
iajs-4030	364	7	raghu	raghu	PROPN
iajs-4030	364	8	g	g	PROPN
iajs-4030	364	9	,	,	PUNCT
iajs-4030	364	10	menon	menon	PROPN
iajs-4030	364	11	rk	rk	PROPN
iajs-4030	364	12	,	,	PUNCT
iajs-4030	364	13	saleem	saleem	PROPN
iajs-4030	364	14	ma	ma	PROPN
iajs-4030	364	15	,	,	PUNCT
iajs-4030	364	16	reddy	reddy	PROPN
iajs-4030	364	17	gb	gb	PROPN
iajs-4030	364	18	.	.	PUNCT
iajs-4030	364	19	carboxymethyl	carboxymethyl	PROPN
iajs-4030	364	20	lysine	lysine	NOUN
iajs-4030	364	21	induces	induce	VERB
iajs-4030	364	22	emt	emt	PROPN
iajs-4030	364	23	in	in	ADP
iajs-4030	364	24	podocytes	podocyte	NOUN
iajs-4030	364	25	through	through	ADP
iajs-4030	364	26	transcription	transcription	NOUN
iajs-4030	364	27	factor	factor	NOUN
iajs-4030	364	28	zeb2	zeb2	PROPN
iajs-4030	364	29	:	:	PUNCT
iajs-4030	364	30	implications	implication	NOUN
iajs-4030	364	31	for	for	ADP
iajs-4030	364	32	podocyte	podocyte	NOUN
iajs-4030	364	33	depletion	depletion	NOUN
iajs-4030	364	34	https://doi.org/10.1038/s41581-021-00408-4	https://doi.org/10.1038/s41581-021-00408-4	NUM
iajs-4030	364	35	https://doi.org/10.1038/s41581-021-00408-4	https://doi.org/10.1038/s41581-021-00408-4	NUM
iajs-4030	364	36	https://doi.org/10.4103%2fijn.ijn_88_21	https://doi.org/10.4103%2fijn.ijn_88_21	ADP
iajs-4030	364	37	https://doi.org/10.1016/b978-0-12-411602-3.00025-1	https://doi.org/10.1016/b978-0-12-411602-3.00025-1	NOUN
iajs-4030	364	38	https://doi.org/10.1093/ndt/gfac045	https://doi.org/10.1093/ndt/gfac045	PROPN
iajs-4030	364	39	https://doi.org/10.3390/ijms22179221	https://doi.org/10.3390/ijms22179221	NOUN
iajs-4030	364	40	https://doi.org/10.3390/toxins14020127	https://doi.org/10.3390/toxins14020127	NOUN
iajs-4030	364	41	https://doi.org/10.32007/jfacmedbagdad.562483	https://doi.org/10.32007/jfacmedbagdad.562483	NOUN
iajs-4030	365	1	https://doi.org/%2010.14744/cpr.2024.92387	https://doi.org/%2010.14744/cpr.2024.92387	NUM
iajs-4030	365	2	https://doi.org/%2010.14744/cpr.2024.92387	https://doi.org/%2010.14744/cpr.2024.92387	NOUN
iajs-4030	365	3	http://dx.doi.org/10.1016/j.mgene.2019.100640	http://dx.doi.org/10.1016/j.mgene.2019.100640	NUM
iajs-4030	365	4	https://doi.org/10.1007/s00018-021-04106-z	https://doi.org/10.1007/s00018-021-04106-z	NOUN
iajs-4030	365	5	https://doi.org/10.1186/s12964-022-00883-7	https://doi.org/10.1186/s12964-022-00883-7	NUM
iajs-4030	365	6	https://doi.org/10.1172/jci71195	https://doi.org/10.1172/jci71195	PROPN
iajs-4030	365	7	.	.	PUNCT
iajs-4030	366	1	https://doi.org/10.1159/000504240	https://doi.org/10.1159/000504240	NOUN
iajs-4030	366	2	https://doi.org/10.1016/b978-0-12-815876-0.00057-7	https://doi.org/10.1016/b978-0-12-815876-0.00057-7	NOUN
iajs-4030	366	3	https://doi.org/10.1016/b978-0-12-815876-0.00057-7	https://doi.org/10.1016/b978-0-12-815876-0.00057-7	ADJ
iajs-4030	366	4	https://doi.org/10.1681/asn.2006010033	https://doi.org/10.1681/asn.2006010033	PROPN
iajs-4030	366	5	ihjpas	ihjpa	VERB
iajs-4030	366	6	.	.	PUNCT
iajs-4030	367	1	38(3)2025	38(3)2025	NUM
iajs-4030	367	2	283	283	NUM
iajs-4030	367	3	and	and	CCONJ
iajs-4030	367	4	proteinuria	proteinuria	NOUN
iajs-4030	367	5	in	in	ADP
iajs-4030	367	6	diabetes	diabetes	NOUN
iajs-4030	367	7	mellitus	mellitus	NOUN
iajs-4030	367	8	.	.	PUNCT
iajs-4030	368	1	arch	arch	ADJ
iajs-4030	368	2	biochem	biochem	PROPN
iajs-4030	368	3	biophys	biophy	NOUN
iajs-4030	368	4	.	.	PUNCT
iajs-4030	369	1	2016	2016	NUM
iajs-4030	369	2	;	;	PUNCT
iajs-4030	370	1	590:10–19	590:10–19	NUM
iajs-4030	370	2	.	.	PUNCT
iajs-4030	371	1	https://doi.org/10.1016/j.abb.2015.11.003	https://doi.org/10.1016/j.abb.2015.11.003	PROPN
iajs-4030	371	2	.	.	PROPN
iajs-4030	371	3	45	45	NUM
iajs-4030	371	4	.	.	PUNCT
iajs-4030	372	1	ahmed	ahmed	PROPN
iajs-4030	372	2	hsh	hsh	PROPN
iajs-4030	372	3	.	.	PUNCT
iajs-4030	373	1	correlations	correlation	NOUN
iajs-4030	373	2	between	between	ADP
iajs-4030	373	3	serum	serum	NOUN
iajs-4030	373	4	interleukins‑2,‑4	interleukins‑2,‑4	NOUN
iajs-4030	373	5	levels	level	NOUN
iajs-4030	373	6	and	and	CCONJ
iajs-4030	373	7	some	some	DET
iajs-4030	373	8	biochemical	biochemical	ADJ
iajs-4030	373	9	parameters	parameter	NOUN
iajs-4030	373	10	in	in	ADP
iajs-4030	373	11	iraqi	iraqi	ADJ
iajs-4030	373	12	patients	patient	NOUN
iajs-4030	373	13	with	with	ADP
iajs-4030	373	14	osteoporosis	osteoporosis	NOUN
iajs-4030	373	15	.	.	PUNCT
iajs-4030	374	1	j	j	PROPN
iajs-4030	374	2	fac	fac	PROPN
iajs-4030	374	3	med	med	PROPN
iajs-4030	374	4	baghdad	baghdad	PROPN
iajs-4030	374	5	.	.	PUNCT
iajs-4030	375	1	2017	2017	NUM
iajs-4030	375	2	;	;	PUNCT
iajs-4030	375	3	59(3):275–279	59(3):275–279	NUM
iajs-4030	375	4	.	.	PUNCT
iajs-4030	375	5	https://doi.org/10.32007/jfacmedbagdad.593103	https://doi.org/10.32007/jfacmedbagdad.593103	NOUN
iajs-4030	375	6	.	.	PUNCT
iajs-4030	376	1	46	46	NUM
iajs-4030	376	2	.	.	PUNCT
iajs-4030	377	1	li	li	PROPN
iajs-4030	377	2	n	n	PROPN
iajs-4030	377	3	,	,	PUNCT
iajs-4030	377	4	jiang	jiang	PROPN
iajs-4030	377	5	p	p	PROPN
iajs-4030	377	6	,	,	PUNCT
iajs-4030	377	7	du	du	PROPN
iajs-4030	377	8	w	w	PROPN
iajs-4030	377	9	,	,	PUNCT
iajs-4030	377	10	wu	wu	PROPN
iajs-4030	377	11	z	z	PROPN
iajs-4030	377	12	,	,	PUNCT
iajs-4030	377	13	li	li	PROPN
iajs-4030	377	14	c	c	PROPN
iajs-4030	377	15	,	,	PUNCT
iajs-4030	377	16	qiao	qiao	PROPN
iajs-4030	377	17	m	m	PROPN
iajs-4030	377	18	,	,	PUNCT
iajs-4030	377	19	yang	yang	PROPN
iajs-4030	377	20	x	x	PROPN
iajs-4030	377	21	,	,	PUNCT
iajs-4030	377	22	wu	wu	PROPN
iajs-4030	377	23	m.	m.	NOUN
iajs-4030	377	24	siva1	siva1	PROPN
iajs-4030	377	25	suppresses	suppress	VERB
iajs-4030	377	26	epithelial‑	epithelial‑	NOUN
iajs-4030	377	27	mesenchymal	mesenchymal	ADJ
iajs-4030	377	28	transition	transition	NOUN
iajs-4030	377	29	and	and	CCONJ
iajs-4030	377	30	metastasis	metastasis	NOUN
iajs-4030	377	31	of	of	ADP
iajs-4030	377	32	tumor	tumor	NOUN
iajs-4030	377	33	cells	cell	NOUN
iajs-4030	377	34	by	by	ADP
iajs-4030	377	35	inhibiting	inhibit	VERB
iajs-4030	377	36	stathmin	stathmin	ADJ
iajs-4030	377	37	and	and	CCONJ
iajs-4030	377	38	stabilizing	stabilize	VERB
iajs-4030	377	39	microtubules	microtubule	NOUN
iajs-4030	377	40	.	.	PUNCT
iajs-4030	378	1	proc	proc	PROPN
iajs-4030	378	2	natl	natl	PROPN
iajs-4030	378	3	acad	acad	PROPN
iajs-4030	378	4	sci	sci	PROPN
iajs-4030	378	5	usa	usa	PROPN
iajs-4030	378	6	.	.	PROPN
iajs-4030	378	7	2011	2011	NUM
iajs-4030	378	8	;	;	PUNCT
iajs-4030	378	9	108(31):12851–12856	108(31):12851–12856	NUM
iajs-4030	378	10	.	.	PUNCT
iajs-4030	378	11	https://doi.org/10.1073/pnas.1017372108	https://doi.org/10.1073/pnas.1017372108	PROPN
iajs-4030	378	12	.	.	PUNCT
iajs-4030	379	1	47	47	NUM
iajs-4030	379	2	.	.	PUNCT
iajs-4030	380	1	luyckx	luyckx	PROPN
iajs-4030	380	2	va	va	PROPN
iajs-4030	380	3	,	,	PUNCT
iajs-4030	380	4	rule	rule	NOUN
iajs-4030	380	5	ad	ad	NOUN
iajs-4030	380	6	,	,	PUNCT
iajs-4030	380	7	tuttle	tuttle	PROPN
iajs-4030	380	8	kr	kr	PROPN
iajs-4030	380	9	,	,	PUNCT
iajs-4030	380	10	delanaye	delanaye	VERB
iajs-4030	380	11	p	p	PRON
iajs-4030	380	12	,	,	PUNCT
iajs-4030	380	13	liapis	liapi	VERB
iajs-4030	380	14	h	h	NOUN
iajs-4030	380	15	,	,	PUNCT
iajs-4030	380	16	gandjour	gandjour	NOUN
iajs-4030	380	17	a	a	PRON
iajs-4030	380	18	,	,	PUNCT
iajs-4030	380	19	romagnani	romagnani	PROPN
iajs-4030	380	20	p	p	X
iajs-4030	380	21	,	,	PUNCT
iajs-4030	380	22	anders	ander	NOUN
iajs-4030	380	23	h‑j	h‑j	NOUN
iajs-4030	380	24	.	.	PUNCT
iajs-4030	381	1	nephron	nephron	NOUN
iajs-4030	381	2	overload	overload	NOUN
iajs-4030	381	3	as	as	ADP
iajs-4030	381	4	a	a	DET
iajs-4030	381	5	therapeutic	therapeutic	ADJ
iajs-4030	381	6	target	target	NOUN
iajs-4030	381	7	to	to	PART
iajs-4030	381	8	maximize	maximize	VERB
iajs-4030	381	9	kidney	kidney	NOUN
iajs-4030	381	10	lifespan	lifespan	NOUN
iajs-4030	381	11	.	.	PUNCT
iajs-4030	382	1	nat	nat	PROPN
iajs-4030	382	2	rev	rev	VERB
iajs-4030	382	3	nephrol	nephrol	NOUN
iajs-4030	382	4	.	.	PUNCT
iajs-4030	382	5	2022	2022	NUM
iajs-4030	382	6	;	;	PUNCT
iajs-4030	382	7	18(3	18(3	NUM
iajs-4030	382	8	):	):	PUNCT
iajs-4030	382	9	171–183	171–183	NUM
iajs-4030	382	10	.	.	PUNCT
iajs-4030	382	11	https://doi.org/10.1038/s41581-021-00510-7	https://doi.org/10.1038/s41581-021-00510-7	PROPN
iajs-4030	382	12	.	.	PUNCT
iajs-4030	383	1	48	48	NUM
iajs-4030	383	2	.	.	PUNCT
iajs-4030	384	1	tahir	tahir	PROPN
iajs-4030	384	2	nt	nt	PROPN
iajs-4030	384	3	,	,	PUNCT
iajs-4030	384	4	ahmed	ahmed	PROPN
iajs-4030	384	5	hs	hs	PROPN
iajs-4030	384	6	,	,	PUNCT
iajs-4030	384	7	gaiz	gaiz	PROPN
iajs-4030	384	8	aa	aa	PROPN
iajs-4030	384	9	.	.	PUNCT
iajs-4030	385	1	leptin	leptin	NOUN
iajs-4030	385	2	and	and	CCONJ
iajs-4030	385	3	insulin	insulin	NOUN
iajs-4030	385	4	resistance	resistance	NOUN
iajs-4030	385	5	in	in	ADP
iajs-4030	385	6	obese	obese	ADJ
iajs-4030	385	7	children	child	NOUN
iajs-4030	385	8	.	.	PUNCT
iajs-4030	386	1	al‑kindy	al‑kindy	PROPN
iajs-4030	386	2	col	col	PROPN
iajs-4030	386	3	med	med	PROPN
iajs-4030	386	4	j.	j.	PROPN
iajs-4030	386	5	2014	2014	NUM
iajs-4030	386	6	;	;	PUNCT
iajs-4030	386	7	10(2):36–40	10(2):36–40	NUM
iajs-4030	386	8	.	.	PUNCT
iajs-4030	387	1	https://jkmc.uobaghdad.edu.iq/index.php/medical/article/view/449	https://jkmc.uobaghdad.edu.iq/index.php/medical/article/view/449	PROPN
iajs-4030	387	2	.	.	PROPN
iajs-4030	387	3	49	49	NUM
iajs-4030	387	4	.	.	PUNCT
iajs-4030	388	1	tahir	tahir	PROPN
iajs-4030	388	2	nt	nt	PROPN
iajs-4030	388	3	,	,	PUNCT
iajs-4030	388	4	ahmed	ahmed	PROPN
iajs-4030	388	5	hs	hs	PROPN
iajs-4030	388	6	,	,	PUNCT
iajs-4030	388	7	ahmed	ahmed	PROPN
iajs-4030	388	8	hs	hs	PROPN
iajs-4030	388	9	.	.	PROPN
iajs-4030	388	10	studies	study	NOUN
iajs-4030	388	11	on	on	ADP
iajs-4030	388	12	the	the	DET
iajs-4030	388	13	role	role	NOUN
iajs-4030	388	14	of	of	ADP
iajs-4030	388	15	retinol	retinol	NOUN
iajs-4030	388	16	binding	bind	VERB
iajs-4030	388	17	protein‑4	protein‑4	PROPN
iajs-4030	388	18	in	in	ADP
iajs-4030	388	19	type	type	NOUN
iajs-4030	388	20	 	 	SPACE
iajs-4030	388	21	2	2	NUM
iajs-4030	388	22	diabetic	diabetic	ADJ
iajs-4030	388	23	iraqi	iraqi	ADJ
iajs-4030	388	24	patients	patient	NOUN
iajs-4030	388	25	with	with	ADP
iajs-4030	388	26	metabolic	metabolic	NOUN
iajs-4030	388	27	syndrome	syndrome	NOUN
iajs-4030	388	28	.	.	PUNCT
iajs-4030	389	1	nucleus	nucleus	NOUN
iajs-4030	389	2	.	.	PUNCT
iajs-4030	390	1	2023:1–7	2023:1–7	X
iajs-4030	390	2	.	.	PUNCT
iajs-4030	390	3	https://doi.org/10.32007/jfacmedbagdad.593103	https://doi.org/10.32007/jfacmedbagdad.593103	NOUN
iajs-4030	390	4	.	.	PUNCT
iajs-4030	391	1	50	50	NUM
iajs-4030	391	2	.	.	PUNCT
iajs-4030	392	1	li	li	PROPN
iajs-4030	392	2	x	x	PROPN
iajs-4030	392	3	,	,	PUNCT
iajs-4030	392	4	zhang	zhang	PROPN
iajs-4030	392	5	y	y	PROPN
iajs-4030	392	6	,	,	PUNCT
iajs-4030	392	7	xing	xing	PROPN
iajs-4030	392	8	x	x	PROPN
iajs-4030	392	9	,	,	PUNCT
iajs-4030	392	10	li	li	PROPN
iajs-4030	392	11	m	m	PROPN
iajs-4030	392	12	,	,	PUNCT
iajs-4030	392	13	liu	liu	PROPN
iajs-4030	392	14	y	y	PROPN
iajs-4030	392	15	,	,	PUNCT
iajs-4030	392	16	xu	xu	PROPN
iajs-4030	392	17	a	a	X
iajs-4030	392	18	,	,	PUNCT
iajs-4030	393	1	zhang	zhang	PROPN
iajs-4030	393	2	jl	jl	PROPN
iajs-4030	393	3	.	.	PUNCT
iajs-4030	394	1	podocyte	podocyte	NOUN
iajs-4030	394	2	injury	injury	NOUN
iajs-4030	394	3	of	of	ADP
iajs-4030	394	4	diabetic	diabetic	ADJ
iajs-4030	394	5	nephropathy	nephropathy	NOUN
iajs-4030	394	6	:	:	PUNCT
iajs-4030	394	7	novel	novel	ADJ
iajs-4030	394	8	mechanism	mechanism	NOUN
iajs-4030	394	9	discovery	discovery	NOUN
iajs-4030	394	10	and	and	CCONJ
iajs-4030	394	11	therapeutic	therapeutic	ADJ
iajs-4030	394	12	prospects	prospect	NOUN
iajs-4030	394	13	.	.	PUNCT
iajs-4030	394	14	biomed	biome	VERB
iajs-4030	394	15	pharmacother	pharmacother	ADJ
iajs-4030	394	16	.	.	PUNCT
iajs-4030	395	1	2023	2023	NUM
iajs-4030	395	2	;	;	PUNCT
iajs-4030	395	3	168:115670	168:115670	X
iajs-4030	395	4	.	.	PUNCT
iajs-4030	396	1	https://doi.org/10.1016/j.biopha.2023.115670	https://doi.org/10.1016/j.biopha.2023.115670	PROPN
iajs-4030	396	2	.	.	PUNCT
iajs-4030	397	1	https://doi.org/10.1016/j.abb.2015.11.003	https://doi.org/10.1016/j.abb.2015.11.003	PROPN
iajs-4030	397	2	.	.	PUNCT
iajs-4030	397	3	https://doi.org/10.32007/jfacmedbagdad.593103	https://doi.org/10.32007/jfacmedbagdad.593103	PROPN
iajs-4030	397	4	https://doi.org/10.1073/pnas.1017372108	https://doi.org/10.1073/pnas.1017372108	NOUN
iajs-4030	397	5	https://doi.org/10.1038/s41581-021-00510-7	https://doi.org/10.1038/s41581-021-00510-7	NUM
iajs-4030	397	6	https://jkmc.uobaghdad.edu.iq/index.php/medical/article/view/449	https://jkmc.uobaghdad.edu.iq/index.php/medical/article/view/449	PROPN
iajs-4030	397	7	https://doi.org/10.32007/jfacmedbagdad.593103	https://doi.org/10.32007/jfacmedbagdad.593103	NOUN
iajs-4030	397	8	https://doi.org/10.1016/j.biopha.2023.115670	https://doi.org/10.1016/j.biopha.2023.115670	NOUN