id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ijpds-4110	Sanjay Sukumar Saralaya	An overview of solvent-free and solvent/s-involved phosphorylation to synthesize Zoledronic acid	2023	6	.pdf	application/pdf	4431	357	64	ynthesis of Zoledronic acid Z involves the reaction of an acid derivative (2) or its salt (3) with selective p-reagent/s {phosphoric acid (H3PO4), phosphorous acid (H3PO3), phosphorous trichloride (PCl3), phosphorous oxychloride (POCl3), triphosgene, mesyl chloride, etc} in the presence of suitable solvent/s or in the absence of solvent at a suitable temperature. Hu W., et al, in 2002, had illustrated the condensation of key starting material 1-H-imidazole (1) with ethyl-chloroacetate (4) and then hydrolyzed to isolate (3).	cache/ijpds-4110.pdf	txt/ijpds-4110.txt