        item: #1 of 77
          id: ijpds-2438
      author: Tahilani, Praveen; Banweer, Jitendra; Chatterjee, D P; Goyanar, Gaurav; Sharma, Abhishek
       title: Nutraceuticals and Fortified Foods Supplements in India: Challenges and Opportunities - A Comprehensive Review
        date: 2023
       words: 3307
      flesch: 58
     summary: [7] Another term often used as a synonym with functional foods is “nutraceuticals,” Several factors are responsible for the fact that this is one of the most promising areas of research in the nutrition sciences today which gives an emphasis in nutritional and medical research on associations between diet and dietary constituents and health benefits, and a favorable regulatory environment including the consumer self- care phenomenon, and rapid growth in the market for health and wellness products is observed [8]. Functional foods of animal origin: Recently the most popular class of physiologically-active components derived from animal products are the (n-3) fatty acids, predominantly found in fatty fish such as salmon, tuna, mackerel, sardines and herring
    keywords: disease; foods; fortification; health; human; india; institute; nutraceuticals; nutrition; research
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        item: #2 of 77
          id: ijpds-2904
      author: Sakshi; Singh, Gaaminepreet
       title: Role of membrane transporters in Cisplatin induced nephrotoxicity
        date: 2023
       words: 3788
      flesch: 49
     summary: Copper Transporter 1 (CTR1) Copper transporter 1 (Ctr1, Solute Carrier 31A1-SLC31A1) is a membrane protein that plays a significant role in the cellular cisplatin uptake. Copper Transporter 2 (CTR2) Copper transporter 2 (Ctr2, SLC31A2) is a copper transport protein with substantia structural homology to Ctr1.
    keywords: cancer; cells; cisplatin; copper; ctr1; drug; membrane; nephrotoxicity; platinum; transporters
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        item: #3 of 77
          id: ijpds-2950
      author: Sujeetha Purushothaman; Arumugan Vijaya Anand
       title: The Link between Cholesterol and a Brain Disease
        date: 2023
       words: 3721
      flesch: 60
     summary: Physical activity and Alzheimer disease: a protective association. The genetic landscape of Alzheimer disease: clinical implications and perspectives.
    keywords: alzheimer; apoe; brain; cholesterol; disease; lipid; metabolism; risk; studies
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        item: #4 of 77
          id: ijpds-2957
      author: Vasthi Kennedy Evanjelene; Ganesh Velu
       title: Preliminary phytochemical, Proximate and Nutrient Analysis indifferent leaf extracts of Jatropha curcas L
        date: 2023
       words: 4545
      flesch: 57
     summary: Plant extracts were subjected to phytochemical examination, which indicated the existence of constituents with medicinal and physiological properties [27]. [4].Synthetic products abound on the market, with high premiums, adverse side effects, and environmental consequences [5] Medicinal plants and drugs extracted from them, on the other hand, are less expensive and have fewer side effects, making them common with the public [6].
    keywords: analysis; ash; content; curcas; extracts; medicinal; methanol; plants; protein; proximate; value
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        item: #5 of 77
          id: ijpds-2959
      author: Santhadani Lenin; Sujatha Ramasamy; Deivasigamani Revathy
       title: Evaluate the Effectiveness of Phytochemical, Physicochemical and Mineral Analysis of Moringa oleifera (Drum Stick Leaves)
        date: 2023
       words: 3266
      flesch: 57
     summary: Phytochemical Analysis: The qualitative phytochemical study of M. Oleifera leaves was carried out. The presence of heavy metals was determined using elemental analysis, and the results for M. Oleifera leaf powder in ppm are Iron (Fe) - 0.548, Copper (Cu) - 0.075, Manganese (Mn) - 0.038, Zinc (Zn) - 0.138, Nickel (Ni) - 0.133, Cobalt (Co) - 0.547, Lead (Pb) - 0.486, Aluminum (Al) - 1.984, Vanadium (V) - 1.096, Chromium (Cr) - 0.048, Molybdenum (Mo) - 0.137, Mercury (Hg) - 0.145, Arsenic (As) - 0.052, Cadmium (Cd) - 0.098.The most common nutritional deficiency has been described as iron deficiency anemia, which is estimated to affect more than one billion people worldwide
    keywords: analysis; colour; drug; iron; leaves; mineral; moringa; oleifera; plant; properties
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        item: #6 of 77
          id: ijpds-2964
      author: Bhoge ND; Mohite PB; Deshmukh VK; Magare BK
       title: A Comprehensive Review on Synthetic Strategy of Benzothiazole Lead and Pharmacological Importance
        date: 2023
       words: 2664
      flesch: 43
     summary: Fig.2 Compounds chosen for MTT assay Asatkar et al., reported that the aqueous extracts of rice husk derived chemically activated carbon acts as a catalyzed for the synthesis of benzothiazole, benzoxazole and N-benzimidazole in room temperature by converting 2-aminothiophenol, 2amino phenol and ortho-phenylene di-amine with aromatic aldehydes with 98%yeild [7] (Fig. Benzothiazole derivative can be synthesized by using conventional, microwave method or by other green chemistry method.
    keywords: activities; activity; anticancer; benzothiazole; compounds; derivatives; synthesis
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        item: #7 of 77
          id: ijpds-3082
      author: Somanaboina Padmakar
       title: A Case Report on Neurofibromatosis Associated with Infective Mass Tumor
        date: 2023
       words: 1453
      flesch: 59
     summary: 1 Neurofibromas associated with infective mass tumor over left forearm Table 1: Drugs prescribed to the patient Drug name Dose Route Freque ncy Dura tion Inj. International consensus statement on malignant peripheral nerve sheath tumors in neurofibromatosis.
    keywords: mass; neurofibromatosis; nf1; tumor; type
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        item: #8 of 77
          id: ijpds-3102
      author: Nidhi Chauhan; Sonali Agarwa
       title: Piracetam induced psychotic symptoms in a preadolescent girl with intellectual disability
        date: 2023
       words: 1229
      flesch: 35
     summary: No history of seizures, other neurodevelopmental disorders, substance use, skin rash (porphyria), drug use (steroids) was obtained. Casual, unsupervised, nonmedical use of nootropic drugs to improve academic performance could have unanticipated negative mental health effects.
    keywords: disability; drug; effects; piracetam; use
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        item: #9 of 77
          id: ijpds-3132
      author: Vamakshi Thaker; A.K. Singhai; Dilip Kumar Tiwari
       title: Formulation and Characterization of Clotrimazole Micro Emulsion for Topical Drug Delivery
        date: 2023
       words: 4513
      flesch: 55
     summary: Assay % 99.6 ± 0.22 99.1 ± 0.30 99.0 ± 0.30 pH 5.46 ± 0.22 5.4 ± 0.20 5.42 ± 0.20 result of stability of M icro emulsion gel at refriger ation temperature Assay % 99.6 ± 2.42 98.9 ± 1.23 98.6 ± 1.13 pH 5.99 ± 0.20 5.99 ± 0.14 5.97 ± 0.12 Transparency Transparency & clear Transparency & clear Transparency & clear Viscosity Very good Very good Very good Figure 4 - FTIR Spectroscopy of clotrimazole drug. It is sold in most developed countries worldwide under a variety of trade names, and a large number of clotrimazole formulations are available.
    keywords: clotrimazole; clotrimazole micro; drug; emulsion; formulation; gel; micro; micro emulsion; oil
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        item: #10 of 77
          id: ijpds-3133
      author: Raju Maski; Jitendra Banweer; Megha Mishra; Praveen Tahilani; Gaurav Goyanar
       title: Advances in Ocular Drug Delivery System for Glaucoma Management – A Comprehensive Review
        date: 2023
       words: 7951
      flesch: 57
     summary: Bloomfield et al. developed the drug delivery model for the collagen shields. Chauhan et al. developed the technique using Vitamin E as an in-situ transport barrier for timolol.
    keywords: contact; delivery; drug; drug delivery; et al; eye; glaucoma; iop; lenses; nanoparticles; ophthalmol; patients; pharm; pilocarpine; reduction; release; studies; system; timolol
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        item: #11 of 77
          id: ijpds-3217
      author: Marilia Amável Gomes Soares; Otávio Augusto Chaves; Dilson Silva; Dari Cesarin-Sobrinho``; Célia Martins Cortez; Antônio Augusto Fidalgo Neto
       title: Effect of Glucose Concentrations on the HSA-Hydrochlorothiazide Interaction – a study using Circular Dichroism and Molecular Docking
        date: 2023
       words: 4831
      flesch: 60
     summary: For this, HSA solutions containing GLU 80 mg/dl and 320 mg/dl were used named normoglycemic and hyperglycemic solutions, respectively. [22], optical cuvette length (1.0 cm), and molar HSA concentration (10-6 M), respectively.
    keywords: albumin; binding; docking; glucose; hctz; hsa; interaction; structure
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        item: #12 of 77
          id: ijpds-3318
      author: Prathap Bingi; Shaik Kareemulla; B. Himabindu; Khan, D. Sheklane ; Ramu, G. ; Rafi, S. Mahammed 
       title: A Comparitive Study on Efficacy and Safety of Vildagliptin-Metformin versus Glimepiride - Metformin in Type 2 Diabetes Mellitus Patients
        date: 2023
       words: 4361
      flesch: 57
     summary: Figure 3: Graphical representation of patients based on co- morbidities (V-M; G-M) DISCUSSION On evaluation, it was found that a significant reduction of HbA1C, FBS, and RBS levels was noted in VM group patients when compared to GM group patients. In terms of the safety profile, more ADRs were noted in GM group patients than in VM group patients.
    keywords: diabetes; glimepiride; group; metformin; patients; safety; study; type; vildagliptin
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        item: #13 of 77
          id: ijpds-3481
      author: Praveen Tahilani; Hemant Swami; Gaurav Goyanar; Shivani Tiwari
       title: The Era of Artificial Intelligence in Pharmaceutical Industries - A review
        date: 2023
       words: 3172
      flesch: 47
     summary: Artificial intelligence (AI) has become more prevalent in a number of societal fields, most notably the pharmaceutical industry. Artificial intelligence.
    keywords: artificial; data; development; drug; industry; intelligence; learning; pharmaceutical; technology; use
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        item: #14 of 77
          id: ijpds-3504
      author: Sakhare, Ghansham R; Yelwande, Purva ; Suryawanshi, Sandhya ; Ambhore, Kiran ; Pawar, Rutuja ; Jain, Kishor 
       title: Pharmacovigilance study on the increased use of antibiotics in pediatric treatment: Pharmacovigilance of antibiotic usage
        date: 2023
       words: 2952
      flesch: 51
     summary: Around 97 % groups said they went to doctor after occurrence of adverse drug reaction, 98 % percent groups said they were aware of the risks of self-medication. The occurrence of adverse drug reactions (ADR’s) is an-other problem with antibiotic use.
    keywords: adr; antibiotics; drug; groups; pharmacovigilance; use
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        item: #15 of 77
          id: ijpds-3542
      author: Thaker, Vamakshi; Verma, Jyoti; Waghmare, Suchita; Mourya, Navinraj
       title: Formulation and Evaluation of Rapidly Dissolving Film containing Antihistaminic drugs (Levocetirizine dihydrochloride)
        date: 2023
       words: 2671
      flesch: 46
     summary: DISCUSSION The comparison of the effect of individual superdisintegrants on the wetting time, disintegration time and dissolution showed that SSG was more suitable for the formulation of oral dispersible tablets of Levocetirizine dihydrochloride as compared to other superdisintegrants used in the current study. Hence, from the present study, it can be concluded that the Thaker et al. Formulation and Evaluation of Levocetrizine dihydrochloride Vol 2 / Issue 1 / Jan - Mar 2023 Indian J Pharm Drug Studies | 26 superdisintegrants SSG and CP in appropriate concentration can be used to develop oral dispersible tablets of Levocetirizine dihydrochloride by direct compression method.
    keywords: dihydrochloride; disintegration; dissolution; drug; formulation; histamine; levocetirizine; tablets; time
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        item: #16 of 77
          id: ijpds-3543
      author: Sonwani, Hari; Virendra Kumar Sharma; Steffi Thomas; Akhlesh Kumar
       title: Adenosine receptor agonists suppress macrophage inflammatory protein -1α production and collagen induced arthritis
        date: 2023
       words: 5141
      flesch: 51
     summary: We conclude that adenosine receptor agonists, particularly the A3 agonist IB-MECA, inhibit MIP-α synthesis and have anti-inflammatory properties. This LPS concentration is higher than that employed in investigations on the effects of adenosine receptor agonists on MIP-1α generation.
    keywords: adenosine; agonist; arthritis; il-12; lps; meca; mip-1α; production; receptor
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        item: #17 of 77
          id: ijpds-3575
      author: Singh, Ayush ; Isher, Jatin ; Sehgal, Riya; Manju; Kumari, Neeru; Kaur, Karamjit
       title: Molnupiravir and Favipiravir in the therapeutics of SARS-CoV-2 - A review
        date: 2023
       words: 2822
      flesch: 50
     summary: Anti-viral drugs prevent viral replication through several kinds of mechanisms or physiology. It is a selective and potent inhibitor of RdRp of RNA viruses.
    keywords: cov-2; covid-19; drug; favipiravir; molnupiravir; rna; sars; virus
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        item: #18 of 77
          id: ijpds-3583
      author: Shaikhmulani, Hasan; Tamboli, Ashpak M ; Tamboli, Naziya A ; Kshirsagar, Rohan T 
       title: RP-HPLC Method Development and Validation for Simultaneous Estimation of Benidipine Hydrochloride and Chlorthalidone in Pharmaceutical Dosage Form
        date: 2023
       words: 2957
      flesch: 52
     summary: Shaikhmulani et al. RP-HPLC method development and validation of BEN.HCL & CTD Vol 1 | Issue 3 | Oct - Apr 2022 Indian J Pharm Drug Studies | 102 Original Article RP-HPLC Method Development and Validation for Simultaneous Estimation of Benidipine Hydrochloride and Chlorthalidone in Pharmaceutical Dosage Form ABSTRACT A simple, precise, rapid and accurate reverse phase High Performance Liquid Chromatography (HPLC) method was developed for the estimation of Benidipine Hydrochloride and Chlorthalidone in bulk and tablet dosage form.
    keywords: benidipine; chlorthalidone; hydrochloride; method
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        item: #19 of 77
          id: ijpds-3602
      author: Suthar, Pallavi; Mashru, Rajashree
       title: Advanced UV Spectrophotometric Method Development and Validation for Simultaneous Estimation of Azelnidipine and Telmisartan in Pharmaceutical Dosage Form
        date: 2023
       words: 3627
      flesch: 54
     summary: First derivative method LOD AZL 0.35 0.16 1.8 TEL 0.73 0.77 1.71 LOQ AZL 0.927 0.048 5.4 TEL 2.16 2.34 5.16 Table 6 – Two way ANOVA ANOVA Source of Variation SS DF MS F P-Value F Crit Sample 0.59535 3 0.19845 0.710972 0.55952 3.238872 Suthar and Mashru Advanced UV Spectrophotometric Method Development and Validation Vol 2 | Issue 1 | Jan – Mar 2023 Indian J Pharm Drug Studies | 32 Columns 0.464816667 1 0.464816669 1.665263 0.215232 4.493998 Interaction 1.100816667 3 0.366938889 1.314604 0.304208 3.238872 Within 4.466 16 0.279125 Total 6.626983333 23 CONCLUSION The simple, rapid, accurate, and precise simultaneous methods, Q absorbance ratio and first derivative methods of UV spectroscopy have been developed and validated for the routine analysis of AZL and TEL in API and pharmaceutical dosage form. The resulting solutions were analyzed for drug content by spectrophotometric method at 255 nm and 297 nm for AZL and TEL, respectively.
    keywords: azelnidipine; azl; method; simultaneous; telmisartan
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        item: #20 of 77
          id: ijpds-3611
      author: Shinde, Pradnya; Kadav, Shraddha; Kamble, Ashwini; Tamboli, Ashpak
       title: In vitro pharmacological investigation of fruit of Acacia nilotica
        date: 2023
       words: 2684
      flesch: 45
     summary: In comparison to the other fruit concentrates of Acacia nilotica, the 400 g/ml concentration of the Acacia nilotica fruit extract exhibits considerable DPPH free radical scavenging activity of 99.85 percent as shown in table no. 3. In this assay, 0.1 ml of test solution of Acacia nilotica fruit extract of different concentrations (100 g/ml, 200 g/ml, and 500 g/ml produced in methanol) and 0.9 ml of bovine serum albumin (5 percent aqueous solution) were taken in different test tubes.
    keywords: acacia; activity; dpph; extract; fruit; inhibition; nilotica
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        item: #21 of 77
          id: ijpds-3613
      author: Jacson, Janice
       title: Depression among cancer survivors – An untold story
        date: 2023
       words: 3885
      flesch: 50
     summary: Mandumpala Depression among cancer survivors Vol 1 | Issue 3 | Oct - Dec 2022 Indian J Pharm Drug Studies | 79 Review Article Depression among cancer survivors – An untold story Janice Jacson Mandumpala From, Department of Pharmacy Practice, Nirmala College of Pharmacy, Kerala, India Correspondence to: Janice Jacson Mandumpala, Pharm D intern, Department of Pharmacy Practice, Nirmala College of Pharmacy, Muvattupuzha, Ernakulam, Kerala, India. Multi-morbidities, being female, pre-existing psychological illness are few among risk factors that intensify the course of depression among cancer survivors.
    keywords: breast; cancer; cancer survivors; depression; patients; screening; survivors; treatment
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        item: #22 of 77
          id: ijpds-3619
      author: Jacson, Janice; Sebastian, Stephy 
       title: Barriers to Hospital Pharmacy Information System – An emerging concern
        date: 2023
       words: 2912
      flesch: 52
     summary: This review article focuses on various barriers in hospital pharmacy information systems. This review aims to provide the importance of information systems and implement them across various hospitals.
    keywords: healthcare; hospital; information; patient; pharmacy; study; system; technology
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        item: #23 of 77
          id: ijpds-3645
      author: Kumar, Akhil; Jacson, Janice
       title: Potential effects of excessive Energy drinks consumption in young people on long-term cardiovascular risks
        date: 2023
       words: 3252
      flesch: 47
     summary: One of the prominent issues being considered is the link between the risk of developing cardiovascular diseases and energy drink consumption. In the long term, the children and the youth are vulnerable to the dangers of energy drink consumption.
    keywords: caffeine; consumption; drinks; effects; energy; energy drinks; risk
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        item: #24 of 77
          id: ijpds-3650
      author: Baby John, Martin; Rose MS, Alasandra; Jacson, Janice
       title: Over-the-counter medicine abuse – A pharmacist’s emerging responsibility
        date: 2023
       words: 3524
      flesch: 59
     summary: This review gives knowledge on the barriers faced by pharmacists in OTC medication abuse and how it can be controlled and managed effectively. One of the main notable reasons for OTC medication abuse is an increase in access to medications [11,12].
    keywords: abuse; counter; drug; medications; otc; otc medications; patients; pharmacists
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        item: #25 of 77
          id: ijpds-3688
      author: Jacson Mandumpala, Janice
       title: Medication Reconciliation - A patient safety strategy
        date: 2023
       words: 2986
      flesch: 41
     summary: This review summarizes a brief review about what is patient safety, and the patterns of employing medication reconciliation in different clinical scenarios that is the emergency department, in transitions of care and in geriatric care. Key words: Medication reconciliation, Patient safety, Emergency department, Geriatric care, Clinical pharmacists edication reconciliation has the potential to reduce significant morbidity and mortality.
    keywords: care; drug; hospital; medication; patient; pharmacy; reconciliation; safety
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        item: #26 of 77
          id: ijpds-3747
      author: Maryam, Zahra; Ahmad , Ausaf
       title: Comprehensive analysis and critical review of randomized clinical trials on safety profiling of Hydroxychloroquine and Belimumab
        date: 2023
       words: 4625
      flesch: 53
     summary: This comprehensive review is aimed at analyzing the safety profiles of two widely used drugs for SLE Ie HCQ and Belimumab. The present review is aimed at analyzing the safety profiles of HCQ and Belimumab by the critical review as HCQ was recently used in the global pandemic of covid-19 and recent data is available on HCQ safety profiling.
    keywords: belimumab; disorders; effects; hcq; lupus; ratio; results; risk; safety; sle; trials
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        item: #27 of 77
          id: ijpds-3748
      author: Ahmad , Ausaf; Maryam, Zahra
       title: Development and validation of novel stability indicating RP HPLC Method for quantitative Estimation of Empagliflozin in Tablets
        date: 2023
       words: 3661
      flesch: 50
     summary: Jardiance, Glyxambi, Synjardy, and Synjardy XR are examples of Empagliflozin tablets [7-10]. The validation is important as Drug regulatory governing bodies play a vital role and have placed emphasis on drug manufacturing companies to offer comprehensive information regarding the process for the validation of analytical methods C mailto:zahra.maryam489@gmail.com Ahmad et al RP-HPLC Method Validation of Empagliflozin
    keywords: empagliflozin; hplc; method; mobile; phase; results; solution; study; validation
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        item: #28 of 77
          id: ijpds-3844
      author: Preeti Shanbag; Ramdas Bhat; Sweta Prabhu; AR Shabaraya
       title: Screening of antidepressant activity of nelumbo nucifera flower extract in mice
        date: 2023
       words: 2651
      flesch: 57
     summary: Shanbhag et al. nelumbo nucifera flower extract in mice Vol 1 | Issue 3 | Oct – Dec 2022 Indian J Pharm Drug Studies | 108 Original Article Screening of antidepressant activity of nelumbo nucifera flower extract in mice Preeti Shanbhag1, Ramdas Bhat2, Sweta Prabhu3, AR Shabaraya4 From, 1PG Scholar, Department of Pharmacology, 2Assistant Professor, Department of Pharmacology, 3PG Scholar, Department of Pharmaceutics, 4Principal and Professor, Srinivas College of Pharmacy, Valachil, Mangalore, India Corresponding to: Ramdas Bhat, Assistant Professor, Department of Pharmacology, Srinivas College of Pharmacy, Valachil, Screening of antidepressant activity of nelumbo nucifera flower extract in mice.
    keywords: extract; nelumbo; nucifera; test
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        item: #29 of 77
          id: ijpds-3858
      author: N, Varshini; M M, Himasvi; Bhat, Ramdas; A R Shabaraya
       title: Exploring the Novel Norovirus: A Comprehensive Study and Overview
        date: 2023
       words: 2895
      flesch: 54
     summary: Norovirus is spread through contaminated food or water, close contact with infected individuals, or by touching contaminated surfaces and then ingesting the virus. Norovirus also triggers an immune response in the body, which can further contribute to inflammation and damage of the small intestine.
    keywords: contact; food; gastroenteritis; infection; norovirus; people; spread; surfaces
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        item: #30 of 77
          id: ijpds-3865
      author: Jacson, Janice
       title: Ceftriaxone Resistance – A caution for judicial antibiotic use
        date: 2023
       words: 4697
      flesch: 47
     summary: This review summarizes the advent of ceftriaxone resistance among various organisms across the globe. Additionally, a molecular analysis of Salmonella isolates with ceftriaxone resistance has demonstrated a higher production of the CMY-2 and the CTX- M-3 beta-lactamases [11].
    keywords: aeromonas; antibiotic; antimicrobial; ceftriaxone; cephalosporins; drug; gonorrhoeae; infections; neisseria; resistance; salmonella
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        item: #31 of 77
          id: ijpds-3890
      author: Osunga, Salome; Amuka, Omari; Machocho, Alex; Getabu, Albert; Onani, Martin
       title: Some members of genus Cassia (Senna): Their Ethnobotany, Potency and Prospects of Drug discovery
        date: 2023
       words: 13719
      flesch: 62
     summary: Osunga et al. Their Ethnobotany, Potency and Prospects of Drug discovery Vol 2 | Issue 2 | Apr – Jun 2023 Indian J Pharm Drug Studies | 43 N N O N H Cl O 1 H3C CH3 COOHH3CCH3 HO H3C CH3 2 OH HO OHO O O O HO OH OH OH OH HO OH OH HO O 3 4 5 O O HO OH O OH OH O HO OH OH O O H3C HO OH OH O HO OH O O O O O HO HO OH OH 6 9 HO HO OH O 7 8 O HO HO O HO HO O OH OO O OH OH O OH OH HO O HO 10 11 OOH HO O OH OH OH OOH HO O OH 12 13 Osunga et al.
    keywords: 2020; activities; activity; africa; antioxidant; bark; cassia; compounds; discovery; diseases; drug; et al; ethnobotany; extracts; h o; indian; indian j; int; int j; issue; j pharm; jun; leaves; med; o ho; o o; osunga; phytochemical; plant; potency; prospects; res; review; roots; sci; seeds; senna; skin; species; studies; vol
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        item: #32 of 77
          id: ijpds-3902
      author: Viresh K Chandur; Shabaraya A, Ramakrishna
       title: Characterization of Liquid Oral Containing Lycopene Phytosomes for Improved Absorption
        date: 2023
       words: 3056
      flesch: 51
     summary: Chandur & Shabaraya A Containing Lycopene Phytosomes for Improved Absorption Vol 2 | Issue 2 | Apr – Jun 2023 Natural or synthetic phospholipids, such as phosphatidylcholine, were obtained from Hi media, aprotic R mailto:viresh.chandur2009@gmail.com Chandur & Shabaraya A Containing Lycopene Phytosomes for Improved Absorption Vol 2 | Issue 2 | Apr – Jun 2023
    keywords: drug; liquid; lycopene; oral; phytosomes; studies; suspension
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        item: #33 of 77
          id: ijpds-3904
      author: Queeny Wilcy Noronha; Thanshifa Fathima; Bhat, Ramdas; A R Shabaraya
       title: Current and Emerging Pharmacotherapies for Zika Virus: A Comprehensive Review
        date: 2023
       words: 3276
      flesch: 60
     summary: Although other arboviral and non-arboviral conditions might also present with same symptoms, a laboratory confirmation of Zika virus infection is necessary [23]. The risk of congenital deformities following Zika virus infection during pregnancy is unknown; it is estimated that 5-15% of babies born to mothers who contracted the virus while pregnant show signs of Zika-related problems.
    keywords: health; infection; journal; medicine; oct; research; review; virus; zika; zikv
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        item: #34 of 77
          id: ijpds-3935
      author: Shanbhag, Preeti; Bhat, Ramdas; A R Shabaraya
       title: The Potential of siRNA-Mediated Oncogene Silencing in Cancer Therapy: An Overview of Pharmacogenomics Strategies
        date: 2023
       words: 4055
      flesch: 54
     summary: Oncogenes, which are genes that promote the growth and proliferation of cancer cells, have been discovered as promising targets for siRNA-mediated gene silencing in cancer therapy [2]. An overview of the present status of siRNA-mediated oncogene silencing for cancer therapy will be given in this thorough review.
    keywords: cancer; clinical; delivery; drug; sirna; therapies; therapy; treatment
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        item: #35 of 77
          id: ijpds-3960
      author: Viresh K Chandur; Ramakrishna Shabaraya A
       title: Spectrophotometric Characterization of lycopene Phytosomes from Fruit Peels of Lycopersicum esculentum
        date: 2023
       words: 2971
      flesch: 57
     summary: Determination of λmax Figure 1: Determination of λmax of Lycopene form Tomato Peel extract. Non-destructive Measurement of Fresh Tomato Lycopene Content and Other Physicochemical Characteristics Using Visible-NIR Spectroscopy, J. Agric.
    keywords: cm-1; determination; extract; ftir; lycopene; studies; tomato
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        item: #36 of 77
          id: ijpds-3988
      author: Bhat, Ramdas; Hemalatha C H; A R Shabaraya
       title: Exploring the protective effects of aqueous extracts of Ruta Chalepensis Linn. On drug induced seizures in animal models
        date: 2023
       words: 3235
      flesch: 60
     summary: Results: In strychnine induced convulsion test the onset of seizure was significantly delayed in the animals treated with Ruta Chalepensis Linn leaf aqueous extract at 750mg/kg. Conclusion: As a result of foregoing Ruta Chalepensis Linn leaf aqueous extract has considerable diuretic activity at higher doses.
    keywords: aerc; chalepensis; dose; linn; ruta; seizures; strychnine
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        item: #37 of 77
          id: ijpds-4004
      author: Jacson, Janice
       title: A case report on tricyclic antidepressant induced increased blood pressure
        date: 2023
       words: 1719
      flesch: 48
     summary: Administration of tricyclic antidepressants that cause raised blood pressure becomes particularly important in resistant hypertension cases. Although dietary sodium restriction is an important aspect in the control of blood pressure.
    keywords: blood; patient; pressure; tablet
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        item: #38 of 77
          id: ijpds-4051
      author: Jacson Mandumpala, Janice
       title: PRECISION MEDICINE AND CLINICAL PHARMACISTS
        date: 2024
       words: 4383
      flesch: 41
     summary: Figure 1 – Evolving precision medicine techniques for cancer treatment Ethical Issues in precision medicine Precision medicine bases disease treatment and prevention on a patient's unique gene, environmental, and lifestyle variations. The Clinical Pharmacy Advocacy Group emphasizes the need for improved training for chemists in practice as well as students to take precision medicine into account.
    keywords: cancer; data; drug; medicine; patient; pharmacists; precision; precision medicine; role; treatment; vol
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        item: #39 of 77
          id: ijpds-4052
      author: Utpal Bhui; Subhajit Sarkar; Joy Das; Indra Kumar Ghoshal; Abhik Saha; Bimlesh Kumar
       title: Unraveling the Enigma of Anti-Tubercular Drug-Induced Vitamin B6 Deficiency and its Role in Provoking Convulsive Seizures: A Revelatory Case Report
        date: 2023
       words: 1812
      flesch: 51
     summary: 2. Tesfahuneygn G, Medhin G, Legesse M. Adherence to Anti- tuberculosis treatment and treatment outcomes among tuberculosis patients in Alamata District, northeast Ethiopia. Now, as a result of an unfavorable drug reaction to anti-tubercular medications, the patient had acquired acute hepatitis and convulsive seizuresdue to vitamin B6 deficiency.
    keywords: deficiency; drug; hepatotoxicity; patient; tuberculosis; vitamin
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        item: #40 of 77
          id: ijpds-4063
      author: Thrupthi P Rai; Karunakar Hegde; A R Shabaraya
       title: A brief review on Pharmacological potential of Nephelium lappaceum L
        date: 2023
       words: 3067
      flesch: 49
     summary: Key words: Nephelium lappaceum L., Traditional, Phytochemical, Malay-Indonesian, Health he fruit known as Nephelium lappaceum L. is a member of the Sapindaceae family and is indigenous to tropical areas including Indonesia, China, India, Australia, Malaysia, Mexico, and Thailand. CONCLUSION Nephelium lappaceum L., a member of the sapindaceae family and commonly referred to as Rambutan, has been utilized for generations in traditional medicine.
    keywords: activity; extract; fruit; lappaceum; nephelium; nephelium lappaceum; peel; rambutan
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        item: #41 of 77
          id: ijpds-4067
      author: B M Thejaswini; S, Satish; Ramkrishna Shabaraya A
       title: A review on Pharmacological potential of Solanum nigrum: Pharmacological review on Solanum nigrum
        date: 2023
       words: 5729
      flesch: 50
     summary: The results of the present study provide clear evidence of defence provided by Solanum nigrum extract against lead acetate induced toxicity in brains of albino mice [30]. Hepatoprotective activity of Solanum nigrum extracts on chemically induced liver damage in rats.
    keywords: activity; compounds; extract; fruits; leaves; nigrum; plant; properties; review; seeds; solanum; solanum nigrum
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        item: #42 of 77
          id: ijpds-4072
      author: Dsouza, Vinisha Seema
       title: An update on the ayurvedic herb Centella asiatica
        date: 2023
       words: 4425
      flesch: 51
     summary: A review on ayurvedic herb Centella asiatica An update on the ayurvedic herb Centella asiatica Ashoka Shenoy M1, Vinisha Seema Dsouza2, Ramkrishna Shabaraya A3 From 1Assi.
    keywords: acid; activity; anti; antioxidant; asiatica; centella; centella asiatica; effect; extract; plant; rats
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        item: #43 of 77
          id: ijpds-4099
      author: Sonia, Sonia gaonkar
       title: A Brief Review on Pharmacological Potential of Brassica oleracea sprouts
        date: 2023
       words: 2958
      flesch: 56
     summary: The anti-cancer and antioxidant properties of broccoli sprouts have drawn the most interest and have been the subject of substantial research in recent years. The current study shows that broccoli sprouts are an excellent source of natural antioxidants
    keywords: activity; brassica; brassica oleracea; broccoli; italica; oleracea; potential; review; sprouts
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        item: #44 of 77
          id: ijpds-4107
      author: Supriya Mhamane; Yogesh Shinde
       title: In-vitro anti-solar activity of peel of Malus domestica
        date: 2024
       words: 1600
      flesch: 67
     summary: Pawar D. B. et al, “Study on anti-solar activity of ethanolic extract of leaves of ipomoea batatas linn”, World Journal of Pharmaceutical Research 2014; 3(5):382-386. In-vitro anti-solar activity of peel of Malus domestica.
    keywords: activity; domestica; malus
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        item: #45 of 77
          id: ijpds-4110
      author: Sanjay Sukumar Saralaya
       title: An overview of solvent-free and solvent/s-involved phosphorylation to synthesize Zoledronic acid
        date: 2023
       words: 4431
      flesch: 64
     summary: ynthesis of Zoledronic acid Z involves the reaction of an acid derivative (2) or its salt (3) with selective p-reagent/s {phosphoric acid (H3PO4), phosphorous acid (H3PO3), phosphorous trichloride (PCl3), phosphorous oxychloride (POCl3), triphosgene, mesyl chloride, etc} in the presence of suitable solvent/s or in the absence of solvent at a suitable temperature. Hu W., et al, in 2002, had illustrated the condensation of key starting material 1-H-imidazole (1) with ethyl-chloroacetate (4) and then hydrolyzed to isolate (3).
    keywords: acid; h3po3; pcl3; phosphorylation; solvent; yield; zoledronic
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        item: #46 of 77
          id: ijpds-4117
      author: Mhamane, Supriya; Adat, Priyanka
       title: In-vitro Anti-Diabetic activity of leaves of Cicer arietinum
        date: 2024
       words: 1933
      flesch: 52
     summary: CONCLUSION These studies conclude that, the ethanolic and hydro-alcoholic extract of leaves of Cicer arietinum shows anti-diabetic activity by alpha amylase inhibition assay. In-vitro anti-diabetic activity of leaves of Cicer arietinum.
    keywords: activity; amylase; cicer; extract; inhibition
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        item: #47 of 77
          id: ijpds-4118
      author: Supriya Mhamane; Priyanka Adat
       title: In-vitro anti-inflammatory activity of leaves of Cicer arietinum
        date: 2024
       words: 1896
      flesch: 50
     summary: This study shows that Cicer arietinum leaves anti-inflammatory activity. CONCLUSION Based on this study, it is concluded that the ethanolic and hydro-alcoholic extract of leaves of Cicer arietinum shows anti-inflammatory activity by inhibition of protein denaturation activity further studies were suggested to isolate the active principles responsible for the activity.
    keywords: activity; cicer; extract; inflammation; inhibition
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        item: #48 of 77
          id: ijpds-4119
      author: Mhamane, Supriya; Adat, Priyanka
       title: In-vitro anti-oxidant activity of leaves of Cicer arietinum
        date: 2024
       words: 1314
      flesch: 51
     summary: The conclusion of this study shows that, the ethanolic and hydro-alcoholic extract of leaves of Cicer arietinum shows anti-oxidant activity by DPPH free radical scavenging activity. In-vitro anti-oxidant activity of leaves of Cicer arietinum.
    keywords: activity; cicer; dpph; extract; percentage
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        item: #49 of 77
          id: ijpds-4128
      author: Ramdas Bhat; Preeti Shanbhag
       title: Marburg Virus Disease: Latest Outbreak and Current Research Review
        date: 2024
       words: 2919
      flesch: 45
     summary: Key words: Marburg virus disease (MVD), viral hemorrhagic fever, Outbreaks, Antiviral therapies, Vaccines. arburg virus disease (MVD) is a severe and often fatal viral illness caused by the Marburg virus (MARV), a member of the Filovirus family [1]. Epidemiology of Marburg Virus Disease The epidemiology of Marburg virus disease (MVD) involves studying its distribution, patterns, and determinants within populations.
    keywords: disease; doi; marburg; marburg virus; mvd; outbreaks; research; review; virus
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        item: #50 of 77
          id: ijpds-4154
      author: Mhamane, Supriya; Kadam, Revati
       title: Herbal face pack formulation from Citrullus lanatus
        date: 2024
       words: 2061
      flesch: 66
     summary: Herbal face pack formulation from Citrullus lanatus. Keywords: Citrullus lanatus, Herbal face pack, Rind powder, Humectant, Anti-acne.
    keywords: evaluation; face; formulation; pack; value
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        item: #51 of 77
          id: ijpds-4194
      author: Krisnendu Das; Utpal Bhui; Arghya Majumdar; Sanmoy Karmakar
       title: Incidence of thrombocytopenia one month after initiation of heparin during hemodialysis: A n observational study
        date: 2024
       words: 3364
      flesch: 47
     summary: Key words: Contaminated heparin, Oversulfated chondroitin sulphate, Heparin-induced thrombocytopenia, End-stage renal disease, Anti heparin platelet factor 4 antibodies hrombocytopenia, or low platelet count, defined as a platelet count below 150 × 109/L, can be broadly classified as congenital and acquired. All of them had platelet counts checked after starting hemodialysis as per protocol.
    keywords: age; count; figure; hemodialysis; heparin; hit; patients; platelet; study; thrombocytopenia
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        item: #52 of 77
          id: ijpds-4231
      author: Sukumar Saralaya, Sanjay
       title: An overview of prior patents for the sequential progress in the synthetic approaches of Rasagiline, its salts, crystallographic forms and impurities
        date: 2024
       words: 10244
      flesch: 43
     summary: Gutman AL, Zaltzman I, Ponomarev V, et al. Process for the preparation of rasagiline and its salts. Sathe DG, Damle SV, Sawant KD, et al. Process for preparation of rasagiline and salts thereof.
    keywords: acid; alcohol; base; et al; form; hplc; hydrochloride; isopropyl; melting; point; preparation; presence; process; publication; purity; racemic; rasagiline; rasagiline base; salts; sodium; yield
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        item: #53 of 77
          id: ijpds-4279
      author: Muskan Altaf Tamboli; Rutuja Ramdas Bhosale; Naziya Ashpak Tamboli
       title: Natural Immunomodulators: Promising Therapy for Disease Management
        date: 2024
       words: 5505
      flesch: 40
     summary: Immune response in this type is mediated largely by humoral antibodies (B cell-mediated). These diseases arise because of the emergence of immune responses against self–antigens [6].
    keywords: acid; anti; antioxidant; cells; diseases; drug; effects; immune; immunity; immunomodulatory; indian; nutraceuticals; reaction; response; studies; system; tamboli; type
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        item: #54 of 77
          id: ijpds-4323
      author: Shrijita Sikdar; Udita Dutta; Ayan Ghosh; Suparna Mondal; Krisnendu Das
       title: Epilepsy Unveiled: Advances in Understanding, Diagnosis, and Management
        date: 2024
       words: 4495
      flesch: 52
     summary: Elevated serum concentrations in epilepsy patients are detected in plasma. Despite adequate seizure control, a considerable proportion of epilepsy patients have intractable or drug-resistant epilepsy, necessitating the development of novel medications with better side effects and tolerance profiles, even at the expense of efficacy, when compared to existing antiepileptic therapies.
    keywords: advances; brain; drug; efficacy; epilepsy; epileptic; indian; mechanisms; onset; people; research; seizures; studies
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        item: #55 of 77
          id: ijpds-4367
      author: Annayat Ghuman; Mehar Ghuman; Gupta, Pankaj
       title: Application of Alternative Medicine as a Curative Therapy of Oral Mucosal Lesions: A Comprehensive Review
        date: 2024
       words: 4185
      flesch: 53
     summary: This article emphasis the use of various alternative therapies, their advantages, mechanism of actions, side effects and implications in dentistry. When such medicines and related therapies are applied in the dental field, the term holistic dentistry is used.
    keywords: aloe; cancer; dentistry; effects; gel; honey; medicine; study; therapies; treatment; vera
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        item: #56 of 77
          id: ijpds-4396
      author: Bhirich, Nihal; Meknassi, Ghita Salime; Yafout, Mohamed; Elhorr, Hicham; Haj Said, Amal Ait; Mojemmi, Brahim
       title: A review of plants and essential oils effective as natural remedies against bedbugs
        date: 2024
       words: 5419
      flesch: 58
     summary: Substances of natural origin such as plant essential oils, which are secondary metabolites derived from the outer glandular cells of the leaves and stems of aromatic plants [12], are one of the treatment alternatives used to combat bedbugs. Essential oils as fumigants for bed bugs (Hemiptera: Cimicidae).
    keywords: action; bedbugs; camphor; effects; entomol; insecticides; leaves; oils; plants; review; studies; thymol; toxicity; vulgaris
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        item: #57 of 77
          id: ijpds-4398
      author: Bhagyashri D Kolekar; Namrata N Gawade; G K Dyade; Nilesh Y Jadhav
       title: Chemo metric assisted Spectrophotometric Method Development through Quality by design Approach for the estimation of Bilastine and Montelukast sodium in combined solid dosage form
        date: 2024
       words: 5055
      flesch: 54
     summary: Also some regulatory guidelines have mentioned flexibility of changing analytical method without revalidation if the AQbD approach has been implemented during analytical method development. Development of various pharmaceutical processes including analytical methods by applying Quality by design aids in ensuring the robustness of the method.
    keywords: bilastine; bse; development; dosage; estimation; hplc; method; mks; montelukast; montelukast sodium; sodium; validation
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        item: #58 of 77
          id: ijpds-4437
      author: Bhat, Ramdas; Saleem, Fazeela Mohammed; Shabaraya, AR
       title: Assessing Self-Medication Practices: A Cross-Sectional Study on Implications and Challenges
        date: 2024
       words: 3298
      flesch: 44
     summary: While convenience and cost- effectiveness drive self-medication, contrasting concerns about adverse effects and misdiagnosis highlight the imperative for responsible medication practices. The survey gathered data on the reasons why individuals choose to self-medicate, the types of medications they use, the sources of information they rely on, and their awareness of the potential risks and benefits of self-medication.
    keywords: health; medication; prevalence; respondents; self; study
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        item: #59 of 77
          id: ijpds-4459
      author: Bhat, Ramdas; Shanbhag, Preeti 
       title: Emerging Trends in Biomaterials for Cancer Immunotherapy and Genome Editing: A Comprehensive Review
        date: 2024
       words: 6114
      flesch: 37
     summary: Examples such as Daliyno (tilmesogenecel), Breyanzi (lisocabtagenedarolumab), and Tecartus (breceltinib) utilize a patient's own tumor-infiltrating lymphocytes (TILs) or engineered CAR T-cells to precisely target melanoma, large B-cell lymphoma, and mantle cell lymphoma [8].Cancer Vaccines, including Gvax (rasilmuplasmid), Papillomavirus vaccines (Gardasil, Cervarix), and personalized neoantigen vaccines, stimulate the immune system to identify and eliminate cancer cells, showcasing a personalized treatment approach [9]. __________________________________________________ Correspondence to: Ramdas Bhat, Associate Professor, Dept. of Pharmacology, Srinivas College of Pharmacy, Valachil, Post Farangipete, Mangalore, Karnataka, India-574143. Cancer Vaccines: Biomaterial-based cancer vaccines have emerged as a compelling approach to augment the body immune response against cancer cells [28].
    keywords: biomaterials; cancer; cas9; cells; crispr; delivery; editing; gene; genome; genome editing; immune; immunotherapy; target; therapies; vectors
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        item: #60 of 77
          id: ijpds-4483
      author: M, Ashoka Shenoy; Mahurkar, Nitin
       title: Complementary action of ginger as bioenhancers in the treatment of diabetes
        date: 2024
       words: 4430
      flesch: 47
     summary: RESULTS Diabetic rats treated with glibenclamide and glibenclamide along with ginger extract showed significant reduction in the elevated levels of total cholesterol, triglycerides and LDL cholesterol in comparison to diabetic control group. Results: Diabetic rats treated with glibenclamide and glibenclamide along with ginger extract showed significant (p<0.001) reduction in the elevated levels of total cholesterol, triglycerides and LDL cholesterol in comparison to diabetic control group.
    keywords: control; diabetes; diabetic; extract; ginger; glibenclamide; group; indian; rats; treatment
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        item: #61 of 77
          id: ijpds-4503
      author: Saralaya, Sanjay Sukumar; Hiriyalau, Shashikumar Somashekar
       title: An overview of prior art disclosures about the synthesis of lamotrigine and a glimpse of its closely related compounds
        date: 2024
       words: 5502
      flesch: 57
     summary: With an intention to find an industrially feasible route of synthesis to manufacture 1 in high atom economy, Venkanna G, et al., had disclosed a high yield and an improved process than the past referred routes Scheme 2. Venkanna G, Nagender D, Venkateswarlu P, et al. Process for producing 6-(2, 3-dichlorophenyl)-1, 2, 4-triazine 3,5- diamine(Lamotrigine) and identification, characterization of a new N-methyl impurity.
    keywords: acid; characterization; cl cl; compounds; crystal; drug; et al; lamotrigine; nh2; solvate; studies; synthesis; triazine
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        item: #62 of 77
          id: ijpds-4528
      author: Dave, Pallav
       title: The Role of Pharmacists in Opioid Addiction Management
        date: 2024
       words: 5341
      flesch: 53
     summary: Strategies to identify patient risks of prescription opioid addiction when initiating opioids for pain: A systematic review. The aim of this review is to explore the role of pharmacists in opioid addiction management including prevention, screening, education, naloxone prescribing, counselling, and referral to treatment resources.
    keywords: abuse; addiction; management; misuse; opioid; patients; pharmacists; risk; role; treatment
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        item: #63 of 77
          id: ijpds-4564
      author: Saralaya, Sanjay Sukumar
       title: A comprehensive review of disclosures in academic journals regarding the synthesis of Rasagiline and its closely related compounds along with majorbiological activity advancements
        date: 2024
       words: 7832
      flesch: 56
     summary: Galvão WS & coworkers had reported the kinetic resolution of secondary alcohols (including 60 to isolate the intermediate for R synthesis) using nano-hydrid bio-catalysts [77]. NH2 + .HCl S OO O CH NaOH, TBAB, H 2O NH CH tartaric acid resolution R-R,R tartarate + 3-R,R tartarate avrg yield: 45.0% Racemic oil1 71 ppt Scheme 5: Simple route of Rasagiline synthesis from 1 as per [69].
    keywords: ch3 ch3; compounds; coworkers; derivatives; dihydro-1h; disease; drug; inden-1; nh ch; o ch3; rasagiline; synthesis; yn-1
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        item: #64 of 77
          id: ijpds-4592
      author: Shirsath, Nitin Rajendra; Shitole, Rohit; Jagtap, Vaibhavkumar; Sagare, Abhay Ramling; Goswami, Ajaygiri
       title: Life–Style and Behavioral Changes after COVID-19: A Perspective
        date: 2024
       words: 5325
      flesch: 60
     summary: After COVID-19 impact of interrupted education was?, (e) What do you think about students’ future, due to COVID-19, and (f) what do you learn from the COVID- 19 pandemic? Figure 4: COVID-19 impact on education Learn from COVID-19 pandemic A common perspective on mental health is that it is a behavioural process that enables individuals to balance their needs with those of their surroundings or with other needs.
    keywords: changes; covid-19; education; health; impact; india; life; pandemic; participants; people; study; survey
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        item: #65 of 77
          id: ijpds-4594
      author: Samajdar, Saptarshi; Samajdar, Debojit 
       title: In silico bioactivity prediction and topical formulation of Piper longum root for skin cancer
        date: 2024
       words: 3840
      flesch: 58
     summary: ABSTRACT Background: Skin cancer is exceedingly common and the incidence is rising rapidly. Although the mortality rate for skin cancer is not as large as other cancers but still a steady mortality rate around the world remains.
    keywords: cancer; cream; evaluation; formulation; ligands; longum; piper; samajdar; silico; skin
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        item: #66 of 77
          id: ijpds-4607
      author: K, Pruthviraj; B S, Chethan ; T N, Lohith; N S, Dinesh Babu; R, Chandrakumar; Kumar, Mohan ; G, Shivaraja ; K, Sunil 
       title: Synthesis, evaluation of antimicrobial activity, and DFT analysis of 1-(4,5-diphenyl-1H-imidazol-2-yl)naphthalen-2-ol
        date: 2024
       words: 3559
      flesch: 51
     summary: Pruthviraj et al. Pruthviraj et al.
    keywords: activity; analysis; diphenyl-1h; evaluation; imidazole; potential; studies; synthesis; yl)naphthalen-2
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        item: #67 of 77
          id: ijpds-4623
      author: Bafna, Harshada Rajendra; Shirsath, Nitin Rajendra; Jagtap, Vaibhavkumar Arun
       title: A New Path for Drug Delivery by Multiple Unit Pellet System (MUPS)
        date: 2025
       words: 5607
      flesch: 50
     summary: In medicine, the proportion of drug pellets to cushioning excipients is crucial. Similar therapeutic benefits can be obtained via controlled release capsules, a kind of solid oral formulation that frequently includes a range of coated pellets.
    keywords: coating; compression; delivery; drug; excipients; mups; pellets; pharmaceutical; release; size; system; tablets; technology; unit
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        item: #68 of 77
          id: ijpds-4638
      author: Dyade, G. K. ; Jadhav, R. B.; Repal, Sanket; Uparwad, Shital; Suryawanshi, Prashant; Taware, Aashish ; Khapne, Sonali ; Kokare, Shweta; Dnyaneshwar, Anuse
       title: QBD Approach and Chemo metric Method Development for the estimation of Metoprolol succinate and Cilnidipine in combined solid dosage form
        date: 2024
       words: 4907
      flesch: 50
     summary: Also some regulatory guidelines have mentioned flexibility of changing analytical method without revalidation if the AQbD approach has been implemented during analytical method development. Development of several pharmaceutical processes including analytical methods by applying Quality by design assists in ensuring the robustness of the method.
    keywords: absorbance; analytical; cil; cilnidipine; development; estimation; method; metoprolol; pharmaceutical; qbd; succinate
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        item: #69 of 77
          id: ijpds-4639
      author: Singha, Soumyadip; Nayak, Soumyadip; Bishayee, Rahul; Sarkar, Pritam; Ghosh, Priyanka; Dutta, Udita; Mishra, Poulomi
       title: Decoding Leptin: Unraveling the Role of Leptin Signaling in the BattleagainstObesity
        date: 2024
       words: 5257
      flesch: 50
     summary: Biochimie. 2012; 94(10):2111-5. doi:10.1016/j.biochi.2012.05.010 8. Izquierdo AG, Crujeiras AB, Casanueva FF, et al. Leptin, obesity, and leptin resistance: where are we 25 years later? Liao GY, An JJ, Gharami K, et al.
    keywords: doi; energy; et al; fat; leptin; levels; obese; obesity; receptor; resistance; role; signaling; studies; weight
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        item: #70 of 77
          id: ijpds-4688
      author: Umarkar, Mohit J.; Jibhkate, Pawan V.; Thakare, Payal G.; Banarase, Nilesh B.; Gabhane, Koshish B.; Salode, Vikrant L.
       title: Alum-based Herbal Handwash: Formulation and Evaluation Study
        date: 2024
       words: 4165
      flesch: 62
     summary: Add an equal volume of test solution. Bial’s orcinol test (for pentose sugars): To boil Bial’s reagent, add a few drops of test solution.
    keywords: alum; extract; foam; formulation; handwash; lemon; solution; test; water
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        item: #71 of 77
          id: ijpds-4715
      author: R, Dr. Reshma; K, Dr. Ajnas
       title: A case of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
        date: 2024
       words: 2739
      flesch: 47
     summary: As a result, the onset is unlikely to occur again, while PANDAS symptoms may continue to appear on a regular basis.5 The National Institute of Mental Health’s (NIMH) criteria for PANDAS includes: 6 1. Some children may be unable to function in social or academic settings due to PANDAS symptoms.
    keywords: autoimmune; case; disorder; infection; ocd; pandas; patient; symptoms
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        item: #72 of 77
          id: ijpds-4724
      author: Savvaser, Spandana; Poojary, Rakshitha; Habibullah, Soubiya Mahnoor; M, Ashoka Shenoy
       title: EVALUATION OF ANXIOLYTIC ACTIVITY OF ETHANOLIC EXTRACT OF Phyllanthus niruri LEAVES IN MICE
        date: 2024
       words: 4490
      flesch: 57
     summary: The anxiety disorders are mainly classified as panic disorder, generalized anxiety disorder, post-traumatic stress disorder, obsessive– compulsive disorder, social phobia, and specific phobias.[13] Among anxiety disorders, panic disorder (10.3%), social phobia (2.7%), and generalized anxiety disorder (2.2%) are particularly common.[14] The symptoms and the disorders following anxiety can be due to the impaired regulation of the central nervous system. Various theories, including psychodynamic, psychoanalytic, and genetic perspectives, have been proposed to explain the etiology of anxiety disorders.
    keywords: animals; anxiety; arm; dark; entries; extract; light; mice; niruri; number; phyllanthus; time
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        item: #73 of 77
          id: ijpds-4738
      author: Patil, Rutik Nitin; Deore, Bhupendra L; gurav, Darshan Ganesh
       title: Analytical Method Development and Validation
        date: 2024
       words: 5388
      flesch: 42
     summary: Evaluation and application of best practice in analytical method validation. In the process of finding, developing, and producing medications, analytical methods are crucial.
    keywords: analysis; analyte; detection; development; drug; hplc; limit; method; method development; pharmaceutical; samples; technique; test; validation
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        item: #74 of 77
          id: ijpds-7624
      author: Bharti, Manu ; Bhardwaj, Anjali ; Parveen, Neha ; Gupta, Ashwani 
       title: Evaluation of hair growth potential of Angustifolia leaves hair gel in rats
        date: 2025
       words: 3446
      flesch: 57
     summary: Hair growth studies were performed on Wistar rats by evaluating both qualitative (initiation and completion of hair growth) and quantitative parameters (hair length, follicle count, and histological observations). Table 3: Effect of EESA gel formulation on hair growth initiation, completion time, and growth of hair length *p < 0.05 significant when compared to control (ANOVA followed by Dunnett’s test values are mean ± SEM Figure 3: Hair growth on 0, 10, 20 and 30th day using HG 2 Further, hair follicles, skin thickness, and color were assessed. EESA 2.5% (HG1) showed visible changes from day 20, while EESA 5% (HG2) showed early effects by day 10.
    keywords: anagen; angustifolia; control; eesa; gel; growth; hair; minoxidil; rats; senna
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        item: #75 of 77
          id: ijpds-7762
      author: Agrawal, Rashmi ; Kulkarni, Meghashyama 
       title: Application of Artificial Intelligence in drug discovery, designing, clinical trials and repurposing
        date: 2025
       words: 5185
      flesch: 55
     summary: CONCLUSION Artificial Intelligence has a crucial role in the various stages of drug development, ranging from drug discovery, design, formulation, clinical trials, repositioning, and up to the final market introduction. Agrawal and Kulkarni AI Applications in Drug Discovery and Development Online First Indian J Pharm Drug Studies | 1 Review Article Application of Artificial Intelligence in drug discovery, designing, clinical trials and repurposing Rashmi Agrawal1, Meghashyama Kulkarni2 From, 1Consultant, Devmata Hospital, Bhopal, Madhya Pradesh, India, 2Consulting Oral Pathologist, Bengaluru, Karnataka, India ABSTRACT Drug development, right from discovery, designing, and repurposing, along with various phases to clinical trials, is a complex and time- consuming process that traditionally relies on the experience of labor forces, along with incessant trial-and-error experimentation.
    keywords: data; development; discovery; doi; drug; drug discovery; et al; intelligence; learning; pharmaceutical; target; toxicity; trials
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        item: #76 of 77
          id: ijpds-7913
      author: Agrawal, Rashmi 
       title: Therapeutic Drug Monitoring (TDM): A Necessity in Critical Care and Transplant Settings
        date: 2025
       words: 3549
      flesch: 38
     summary: For therapeutic drug monitoring (TDM) to be effective, the concentration of a medication must be assessed in several physiological fluids. In the last ten years, the theory, practice, and clinical relevance of therapeutic drug monitoring (TDM) have significantly evolved due to the advent of widely accessible and technically proficient modelling, simulation, and dosing software tools [3].
    keywords: care; clinical; dosage; dosing; drug; drug monitoring; monitoring; patients; pharmacokinetic; post; tacrolimus; tdm; toxicity; transplant; trough
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        item: #77 of 77
          id: ijpds-7991
      author: Gandrathi, Srujana ; kumar, Padamatini Naveen ; Baru, Chandrasekhara Rao ; DESAI, SUSHMA; Shiroja, M. ; swetha, Raaga 
       title: Designand Development of Press Coated Pulsatile Release of KetoprofenTablets
        date: 2025
       words: 3746
      flesch: 55
     summary: RESULTS & DISCUSSION Using various polymers (HPMC E5, HPMC E15, Xanthan gum) and a combination of synthetic and natural polymers (HPMC E5 and xanthan gum (1:1 and 3:1), HPMC E5 and HPMC E15 (1:1), HPMC E15 and xanthan gum (1:1, 2:1, and 3:1)), the current study aims to formulate and evaluate Ketoprofen pulsatile tablets. Recent trends in pulsatile drug delivery systems-A review.
    keywords: delivery; drug; formulation; hpmc; ketoprofen; pulsatile; studies; tablets
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