# bib

id: cord-282177-8l7zukg4
author: Lin, Yi-Chun
date: 2020-05-26
extension: .txt
mime: text/plain
words: 371
sentence: 11
flesch: 33
cache: cache/cord-282177-8l7zukg4.txt
txt: txt/cord-282177-8l7zukg4.txt
title:
  A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response

summary:
  Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical characteristics of coronavirus disease 2019 in China Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths A case of COVID-19 and pneumonia returning from Macau in Taiwan: clinical course and anti-SARS-CoV-2 IgG dynamic Dynamics of anti-SARS-Cov-2 IgM and IgG antibodies among COVID-19 patients Laboratory diagnosis of emerging human coronavirus infections-the state of the art Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: An observational cohort study Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 ABSTRACT We report a patient who had travelled to Japan presented mild respiratory symptom during the COVID-19 infection outbreak period.


id: cord-260332-tnz6k2z1
author: Tran, Tu Anh
title: CT scan does not make a diagnosis of Covid-19: a cautionary case report()
date: 2020-09-02
extension: .txt
mime: text/plain
words: 340
sentence: 14
flesch: 53
cache: cache/cord-260332-tnz6k2z1.txt
txt: txt/cord-260332-tnz6k2z1.txt
summary:
  This case must draw attention on the risk of false COVID-19 diagnosis when relying overly on CT scan imaging. RT-PCR assays of nasopharyngeal samples at admittance and 24 hours later, were negative for SARS-CoV-2. Basing Covid-19 diagnosis strictly on clinical signs and imaging may lead to false positive diagnosis, resulting in inappropriate medical care and errors in contact tracing.


id: cord-254776-m4makxr8
author: Luo, Shiua
title: A Follow-up Study of Recovered Patients with COVID-19 in Wuhan, China
date: 2020-06-01
extension: .txt
mime: text/plain
words: 385
sentence: 20
flesch: 54
cache: cache/cord-254776-m4makxr8.txt
txt: txt/cord-254776-m4makxr8.txt
summary:
  The Chinese government has taken serious actions and made unremitted efforts in prevention and control of COVID-19 epidemic, including imposing quarantines and travel restrictions on an unprecedented scale and investing a huge amount of medical resources [2] . Currently, a large number of COVID-19 patients in Wuhan have been cured and discharged.


id: cord-029882-kufs0fxe
author: Malviya, Amit
title: The continued dilemma about usage of Hydroxychloroquine: Respite is in randomized control trials
date: 2020-07-29
extension: .txt
mime: text/plain
words: 485
sentence: 20
flesch: 47
cache: cache/cord-029882-kufs0fxe.txt
txt: txt/cord-029882-kufs0fxe.txt
summary:
  In severe disease with multi system involvement and pro arrhythmic milieu COVID-19: immunopathology and its implications for therapy Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Critically ill SARS-CoV2-infected patients are not stratified as sepsis by the qSOFA Chloroquine and hydroxychloroquine in covid-19 Ventricular arrhythmia risk due to chloroquine / hydroxychloroquine treatment for COVID-19: 9,10 Weather HCQ as initial anti-viral agent prevents progression to severe disease is not known clearly .


id: cord-258881-74aijckl
author: Wang, Maomao
date: 2020-04-23
extension: .txt
mime: text/plain
words: 671
sentence: 29
flesch: 56
cache: cache/cord-258881-74aijckl.txt
txt: txt/cord-258881-74aijckl.txt
title:
  Case Report: One Case of Coronavirus Desease 2019(COVID-19) in Patient Co-nfected by HIV With a Low CD4+ T Cell Count

summary:
  The prominent complaint was dyspnea, The study of Qin showed, The total number of B cells, T cells, and NK cells significantly decreased in patients with COVID-19, and more evident in the severe cases compared to the non-severe group. The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic:an analysis of all 1755 patients Dysregulation of immune response in patients with COVID-19 in Wuhan We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled.


id: cord-268037-szhzmzys
author: Eshaghi, A.
date: 2008-12-17
extension: .txt
mime: text/plain
words: 807
sentence: 26
flesch: 30
cache: cache/cord-268037-szhzmzys.txt
txt: txt/cord-268037-szhzmzys.txt
title:
  A paucity of co-infecting respiratory viral pathogens in nasopharyngeal specimens from patients infected with H274Y-positive influenza A (H1N1) strains

summary:
  1-11 Application of a fluorogenic PCR assay for typing and subtyping of influenza viruses in respiratory samples Neuraminidase subtyping of human influenza A viruses by RT-PCR and its application to clinical isolates Comparison of the Seeplex reverse transcription PCR assay with the R-mix viral culture and immunofluorescence techniques for detection of eight respiratory viruses Emergence of drug-resistant influenza virus: population dynamical considerations Emergence of seasonal influenza viruses type A (H1N1) with oseltamivir resistance in some European countries at the start of the 2007-2008 influenza season.


id: cord-274230-old0xmcc
author: Zhao, Qianwen
date: 2020-05-04
extension: .txt
mime: text/plain
words: 870
sentence: 25
flesch: 33
cache: cache/cord-274230-old0xmcc.txt
txt: txt/cord-274230-old0xmcc.txt
title:
  Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis

summary:
  Mean difference (MD) of lymphocyte count in COVID-19 patients with or without severe disease and odds ratio (OR) of lymphopenia for severe form of COVID-19 was evaluated with this meta-analysis. The pooled analysis showed that lymphocyte count was significantly lower in severe COVID-19 patients (MD -0.31×109/L; 95%CI: -0.42 to -0.19×109/L).


id: cord-272015-1anph6qi
author: Dauby, Nicolas
date: 2020-10-17
extension: .txt
mime: text/plain
words: 962
sentence: 19
flesch: 7
cache: cache/cord-272015-1anph6qi.txt
txt: txt/cord-272015-1anph6qi.txt
title:
  The unfinished story of hydroxychloroquine in COVID-19: the right anti-inflammatory dose at the right moment?

summary:
  In the same line, ongoing trials are investigating colchicine to prevent hospitalisation in SARS-CoV-2 infected subjects, and the rationale is based on anti-inflammatory properties, that are partly shared Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19 The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients Hydroxychloroquine: from malaria to autoimmunity Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19 Hydroxychloroquine Use Is Associated with Lower Odds of Persistently Positive Antiphospholipid Antibodies and/or Lupus Anticoagulant in Systemic Lupus Erythematosus Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study An inflammatory cytokine signature predicts COVID-19 severity and survival Longterm hydroxychloroquine use in patients with rheumatic conditions and development of SARS-CoV-2 infection: a retrospective cohort study Chloroquine inhibits the release of inflammatory cytokines by human lung explants Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis Chloroquine inhibits production of TNF-α, IL-1β and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes Early Hydroxychloroquine but not Chloroquine use reduces ICU admission in COVID-19 patients High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates Colchicine as a possible therapeutic option in COVID-19 infection Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19 Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study World Health Organization Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 HCQ inhibits the production of the pro-inflammatory cytokines interleukin (IL)-6, TNF-α and IL-1-β by activated macrophages (Sperber et al. 1993; Jang et al. 2006) , which are notoriously associated with COVID-19 severity (Webb et al.; Del Valle et al. 2020 ) and also the production of chemotactic cytokines involved in the recruitment of pro-inflammatory cells in the lungs(Grassin-Delyle et al. 2020).


id: cord-279581-d2l4nnex
author: Abuhabib, A.A.
title: Unique situation of Gaza Strip dealing with COVID-19 crisis
date: 2020-09-03
extension: .txt
mime: text/plain
words: 1154
sentence: 31
flesch: 32
cache: cache/cord-279581-d2l4nnex.txt
txt: txt/cord-279581-d2l4nnex.txt
summary:
  [16] towards: assessing potential risks acting as potential scenarios, identifying associated impacts for each risk and suitable mitigation J o u r n a l P r e -p r o o f measures to be considered. J o u r n a l P r e -p r o o f 4 As such, this study aims at assessing and analysing the unique situation of Gaza (characterized by long lasting blockade with restricted movement, dense population, and political implications) in the light of COVID-19 spreading and outlining potential scenarios, both optimistic and pessimistic associated with control measures acting as responsive course of action.


id: cord-274028-dvsvtsn0
author: Del Brutto, Oscar H.
title: SARS-CoV-2-related mortality in a rural Latin American population
date: 2020-08-08
extension: .txt
mime: text/plain
words: 1220
sentence: 52
flesch: 53
cache: cache/cord-274028-dvsvtsn0.txt
txt: txt/cord-274028-dvsvtsn0.txt
summary:
  A sudden increase in adult mortality associated with respiratory diseases was noticed in Atahualpa (a rural Ecuadorian village), coinciding with the introduction of SARS-CoV-2 in the region. A sudden increase in adult mortality associated with respiratory diseases was noticed in Atahualpa, a rural Ecuadorian village (2º18'S, 80º46'W), coinciding with the introduction of SARS-CoV-2 in the region [5] .


id: cord-254377-j8e8gb0l
author: Ali, Sadaf
date: 2020-06-13
extension: .txt
mime: text/plain
words: 1451
sentence: 48
flesch: 29
cache: cache/cord-254377-j8e8gb0l.txt
txt: txt/cord-254377-j8e8gb0l.txt
title:
  Acute cor pulmonale from saddle pulmonary embolism in a patient with previous Covid-19 – should we prolong prophylactic anticoagulation?

summary:
  Clinical Characteristics of Coronavirus Disease 2019 in China Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study Acute Cor Pulmonale in Critically Ill Patients with Covid-19 High risk of thrombosis in patients in severe SARS-CoV-2 infection: a multicenter prospective cohort study Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19 Thrombolytic therapy for pulmonary embolism MARVELOUS Collaborators. We report the case of a 52-year old woman, who presented with massive saddle pulmonary embolism after one week of initial hospital discharge, successfully thrombolysed that raises the question of consideration of extended prophylactic anticoagulation even in low risk Covid-19 cases.


id: cord-283590-xvnv17zy
author: Chen, Dabiao
title: Recurrence of positive SARS-CoV-2 RNA in COVID-19: A case report
date: 2020-03-05
extension: .txt
mime: text/plain
words: 1506
sentence: 63
flesch: 40
cache: cache/cord-283590-xvnv17zy.txt
txt: txt/cord-283590-xvnv17zy.txt
summary:
  Oropharyngeal swab tests of SARS-CoV-2 RNA were performed repeatedly for surveillance (Table 1) . Given the possibility of recurrently positive SARS-CoV-2 RNA in the clinical course and to reduce the risk of transmission in other COVID-19 cases, we suggest that: (1) both nasopharyngeal and oropharyngeal swabs test for SARS-CoV-2 RNA should be performed to reduce the false-negative rate.


id: cord-258078-k7y8k1vx
author: Jang, Sukbin
date: 2020-05-26
extension: .txt
mime: text/plain
words: 1481
sentence: 62
flesch: 43
cache: cache/cord-258078-k7y8k1vx.txt
txt: txt/cord-258078-k7y8k1vx.txt
title:
  Three cases of treatment with Nafamostat in elderly patients with COVID-19 pneumonia who need oxygen therapy

summary:
  We experienced clinical and radiologic improvement in COVID-19 patients with pneumonia treated by nafamostat. These cases were treated with nafamostat in elderly patients with pneumonia who progressed while using antiviral drugs in a high-risk group with limited sample size and not through a randomized control study, and Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak-an update on the status SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Epidemiology, Pathogenesis, and Control of COVID-19 Thromboembolic risk and anticoagulant therapy in COVID-19 patients: Emerging evidence and call for action Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay


id: cord-289304-9srk0ohb
author: Bagnato, Sergio
title: Critical illness myopathy after COVID-19
date: 2020-08-05
extension: .txt
mime: text/plain
words: 1724
sentence: 67
flesch: 40
cache: cache/cord-289304-9srk0ohb.txt
txt: txt/cord-289304-9srk0ohb.txt
summary:
  Since rehabilitation programs can be effective to reverse muscle weakness caused by CIM, health systems must plan to provide adequate access to rehabilitative facilities for patients requiring both pulmonary and motor rehabilitative treatment after COVID-19. key: cord-289304-9srk0ohb authors: Bagnato, Sergio; Boccagni, Cristina; Marino, Giorgio; Prestandrea, Caterina; D’Agostino, Tiziana; Rubino, Francesca title: Critical illness myopathy after COVID-19 date: 2020-08-05 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.07.072 sha: doc_id: 289304 cord_uid: 9srk0ohb We describe a patient who developed diffuse and symmetrical muscle weakness after a long stay in the intensive care unit (ICU) due to coronavirus disease 2019 (COVID-19).


id: cord-271495-5906wju4
author: Beldomenico, Pablo M.
date: 2020-05-11
extension: .txt
mime: text/plain
words: 1995
sentence: 68
flesch: 42
cache: cache/cord-271495-5906wju4.txt
txt: txt/cord-271495-5906wju4.txt
title:
  Do superspreaders generate new superspreaders? a hypothesis to explain the propagation pattern of COVID-19

summary:
  Exposure to high viral loads may result in infections of high intensity, which exposes new cases to high viral loads, and so on. The severity of the disease caused by high viral loads is expected to be high.


id: cord-297715-qcwp2jdv
author: Machida, Masaki
date: 2020-05-17
extension: .txt
mime: text/plain
words: 2156
sentence: 77
flesch: 39
cache: cache/cord-297715-qcwp2jdv.txt
txt: txt/cord-297715-qcwp2jdv.txt
title:
  Changes in implementation of personal protective measures by ordinary Japanese citizens: A longitudinal study from the early phase to the community transmission phase of the COVID-19 outbreak

summary:
  key: cord-297715-qcwp2jdv authors: Machida, Masaki; Nakamura, Itaru; Saito, Reiko; Nakaya, Tomoki; Hanibuchi, Tomoya; Takamiya, Tomoko; Odagiri, Yuko; Fukushima, Noritoshi; Kikuchi, Hiroyuki; Amagasa, Shiho; Kojima, Takako; Watanabe, Hidehiro; Inoue, Shigeru title: Changes in implementation of personal protective measures by ordinary Japanese citizens: A longitudinal study from the early phase to the community transmission phase of the COVID-19 outbreak date: 2020-05-17 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.05.039 sha: doc_id: 297715 cord_uid: qcwp2jdv OBJECTIVES: To clarify changes in the implementation of personal protective measures among ordinary Japanese citizens from the early phase of the COVID-19 outbreak to the community transmission phase.


id: cord-291638-oatrjbo3
author: Kang, Dayun
title: Spatial epidemic dynamics of the COVID-19 outbreak in China
date: 2020-04-03
extension: .txt
mime: text/plain
words: 2639
sentence: 137
flesch: 56
cache: cache/cord-291638-oatrjbo3.txt
txt: txt/cord-291638-oatrjbo3.txt
summary:
  Third, it only investigated spatial spread in mainland China. Spatial analysis is of great help in understanding the spread of infectious diseases, and spatial association was the key to the spatial spread during the early stages of the COVID-19 pandemic in mainland China.


id: cord-008219-ng9xb46c
author: Lassmann, Britta
date: 2016-12-09
extension: .txt
mime: text/plain
words: 2520
sentence: 109
flesch: 43
cache: cache/cord-008219-ng9xb46c.txt
txt: txt/cord-008219-ng9xb46c.txt
title:
  Highlights from the 6(th) International Meeting on Emerging Diseases and Surveillance (IMED 2016) Vienna, Austria from Nov 3 to 7, 2016

summary:
  In a separate session, the challenges posed by climate change on infectious disease outbreaks and how to best prevent and track diseases in mobile populations were discussed. i d During the oral abstract presentation session on One Health -Diseases Across Species Boundaries, Toph Allen from EcoHealth Alliance and colleagues shared results from an updated model assessing the global distribution of zoonotic emerging infectious disease risk.


id: cord-258669-ubw6mdzi
author: Colebunders, Robert
date: 2020-08-27
extension: .txt
mime: text/plain
words: 2517
sentence: 74
flesch: 35
cache: cache/cord-258669-ubw6mdzi.txt
txt: txt/cord-258669-ubw6mdzi.txt
title:
  A call for strengthened evidence on targeted, non-pharmaceutical interventions against COVID-19 for the protection of vulnerable individuals in sub-Saharan Africa

summary:
  We suggest investigating the feasibility, acceptability, and efficacy of distributing COVID-19 prevention kits to households with persons at increased risk for severe COVID-19 disease. One strategy could be to distribute COVID-19 prevention kits to households with persons at increased risk for severe COVID-19 disease.


id: cord-253102-z15j8izi
author: Ross, Allen G.P.
title: Planning for the Next Global Pandemic
date: 2015-08-04
extension: .txt
mime: text/plain
words: 2908
sentence: 134
flesch: 49
cache: cache/cord-253102-z15j8izi.txt
txt: txt/cord-253102-z15j8izi.txt
summary:
  This editorial discusses many issues including priority emerging and re-emerging infectious diseases; the challenges of meeting international health regulations; the strengthening of global health systems; global pandemic funding; and the One Health approach to future pandemic planning. This editorial discusses many issues including priority emerging and reemerging infectious diseases; the challenges of meeting international health regulations; the strengthening of global health systems; global pandemic funding; and the One Health approach to future pandemic planning.


id: cord-306682-01q775up
author: Vijgen, Leen
date: 2004-06-22
extension: .txt
mime: text/plain
words: 2971
sentence: 118
flesch: 47
cache: cache/cord-306682-01q775up.txt
txt: txt/cord-306682-01q775up.txt
title:
  Identification of six new polymorphisms in the human coronavirus 229E receptor gene (aminopeptidase N/CD13)()

summary:
  This region is encoded by the major part of APN exon 3, whole exon 4 and a small part of APN exon 5 (nt 802-1083, hAPN mRNA, GenBank accession number X13276). An 871 bp fragment, encompassing APN exon 3, intron 3 and exon 4 was PCR-amplified and sequenced, and was submitted to GenBank under accession number AF527789.


id: cord-258250-zueo1xfa
author: Hirotsu, Yosuke
date: 2020-08-12
extension: .txt
mime: text/plain
words: 3112
sentence: 127
flesch: 47
cache: cache/cord-258250-zueo1xfa.txt
txt: txt/cord-258250-zueo1xfa.txt
title:
  Comparison of Automated SARS-CoV-2 Antigen Test for COVID-19 Infection with Quantitative RT-PCR using 313 Nasopharyngeal Swabs Including from 7 Serially Followed Patients

summary:
  Antigen tests have been widely applied to detect infection with viruses other than SARS-CoV-2 [16] . Furthermore, both tests are expected to identify the asymptomatic or presymptomatic SARS-CoV-2 infected persons who are likely to have high viral loads.


id: cord-297396-r1p7xn3a
author: Ng, Ming-Yen
title: Development and Validation of Risk Prediction Models for COVID-19 Positivity in a Hospital Setting
date: 2020-09-15
extension: .txt
mime: text/plain
words: 3254
sentence: 136
flesch: 47
cache: cache/cord-297396-r1p7xn3a.txt
txt: txt/cord-297396-r1p7xn3a.txt
summary:
  Reverse transcription polymerase chain reaction (RT-PCR) is regarded as a vital tool in identifying the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and quarantining COVID-19 patients to prevent further spread of the disease 4 . As yet, the data which supports these strategies are predominantly based on data of COVID-19 patients 12, 13 but without comparisons to patients with other conditions and symptoms overlapping with COVID-19 (eg. fever, shortness of breath, cough).


id: cord-301079-n1nytr6k
author: Tan, Li
title: Air and surface contamination by SARS-CoV-2 virus in a tertiary hospital in Wuhan, China
date: 2020-07-27
extension: .txt
mime: text/plain
words: 3558
sentence: 139
flesch: 51
cache: cache/cord-301079-n1nytr6k.txt
txt: txt/cord-301079-n1nytr6k.txt
summary:
  Third, the sensitivity and specificity of RT-PCR tests on surface contamination samples might not be same as those from human specimens. Contamination rates was slightly higher near severe/critical patients compared to those near mild patients, although not statistically significant (p <0.05).


id: cord-300583-0krbrj4w
author: Koh, Wee Chian
title: Estimating the impact of physical distancing measures in containing COVID-19: an empirical analysis
date: 2020-08-13
extension: .txt
mime: text/plain
words: 3745
sentence: 146
flesch: 44
cache: cache/cord-300583-0krbrj4w.txt
txt: txt/cord-300583-0krbrj4w.txt
summary:
  key: cord-300583-0krbrj4w authors: Koh, Wee Chian; Naing, Lin; Wong, Justin title: Estimating the impact of physical distancing measures in containing COVID-19: an empirical analysis date: 2020-08-13 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.08.026 sha: doc_id: 300583 cord_uid: 0krbrj4w BACKGROUND: Epidemic modelling studies predict that physical distancing is critical in containing COVID-19. A combination of physical distancing measures, if implemented early, can be effective in containing COVID-19—tight border controls to limit importation of cases, encouraging physical distancing, moderately stringent measures such as working from home, and a full lockdown in the case of a probable uncontrolled outbreak.


id: cord-290100-wnjjqqn5
author: Wong, Samuel Y.S.
date: 2012-07-11
extension: .txt
mime: text/plain
words: 3952
sentence: 147
flesch: 46
cache: cache/cord-290100-wnjjqqn5.txt
txt: txt/cord-290100-wnjjqqn5.txt
title:
  Primary care physicians’ response to pandemic influenza in Hong Kong: a mixed quantitative and qualitative study

summary:
  12 Acceptability of pandemic influenza vaccination was found to be higher in studies conducted in general practice in France and the Netherlands, at 60% and 80%, respectively. key: cord-290100-wnjjqqn5 authors: Wong, Samuel Y.S.; Kung, Kenny; Wong, Martin C.S.; Wong, Carmen; Tsui, Wendy; Chan, King; Liang, Jun; Lee, Nelson L.S.; Cheung, Annie W.L.; Wong, Eliza L.Y. title: Primary care physicians’ response to pandemic influenza in Hong Kong: a mixed quantitative and qualitative study date: 2012-07-11 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2012.03.015 sha: doc_id: 290100 cord_uid: wnjjqqn5 OBJECTIVES:


id: cord-265146-j0n3a4m6
author: Hsieh, Ying-Hen
title: Ascertaining the 2004–2006 HIV type 1 CRF07_BC outbreak among injecting drug users in Taiwan
date: 2013-02-12
extension: .txt
mime: text/plain
words: 4158
sentence: 155
flesch: 53
cache: cache/cord-265146-j0n3a4m6.txt
txt: txt/cord-265146-j0n3a4m6.txt
summary:
  Correlation results also suggest that the upsurge in male HIV cases led to the subsequent drastic surge in female cases. Correlation results also suggest that the upsurge in male HIV cases led to the subsequent drastic surge in female cases.


id: cord-260518-mswb3q67
author: Zumla, Alimuddin
date: 2016-06-15
extension: .txt
mime: text/plain
words: 4040
sentence: 143
flesch: 36
cache: cache/cord-260518-mswb3q67.txt
txt: txt/cord-260518-mswb3q67.txt
title:
  Taking forward a ‘One Health’ approach for turning the tide against the Middle East respiratory syndrome coronavirus and other zoonotic pathogens with epidemic potential

summary:
  Since the Kingdom of Saudi Arabia is host to millions of pilgrims each year travelling from all continents, 29 tackling the threat of MERS and other infectious diseases with epidemic potential will require enhanced closer cooperation between those who provide human health, animal health, and environmental health services, locally, nationally, regionally, and internationally: the Middle Eastern, European, African, Asian, and American governments, veterinary groups, the WHO, the Food and Agriculture Organization (FAO), the African Union, the United Nations International Children's Emergency Fund (UNICEF), The World Bank, Office International des Epizooties (OIE), CDC, Public Health England, the newly formed Africa CDC, and funding agencies among others. However, MERS-CoV remains a major global public health threat with continuing reports of new human MERS cases in Saudi Arabia, where millions of pilgrims from over 184 countries travel throughout the year.


id: cord-304743-0bsdahh6
author: Kortepeter, Mark G
title: Marburg Virus Disease: a Summary for Clinicians
date: 2020-08-03
extension: .txt
mime: text/plain
words: 1329
sentence: 27
flesch: 8
cache: cache/cord-304743-0bsdahh6.txt
txt: txt/cord-304743-0bsdahh6.txt
summary:
  Vaccine Single-injection vaccine protects nonhuman primates against infection with Marburg virus and three species of ebola virus Postexposure treatment of Marburg virus infections for Marburg virus in nonhuman primates and humans Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against Ebola virus and Marburg virus: results of two single-ascending-dose studies Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!) Clinical syndrome Marburg virus disease Safety and Immunogenicity of Novel Adenovirus Type 26-and Modified Vaccinia Ankara-Vectored Ebola J o u r n a l P r e -p r o o f Vaccines: A Randomized Clinical Trial Durability of a vesicular stomatitis virus-based Marburg virus vaccine in nonhuman primates Therapeutic treatment of Marburg and Ravn virus infection in honhuman primates with a human monoclonal antibody Controlled Trial of Ebola Virus Disease Therapeutics Recent advances in Marburgvirus research Calculation of incubation period and serial interval from multiple outbreaks of Marburg virus disease Online ahead of print Ebola and Marburg virus vaccines Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus Ebola and Marburg hemorrhagic fever Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone Experimental treatment with favipiravir for Ebola virus disease (the JIKI trial): a historically controlled, single-arm proof-of-concept trial in Guinea Interferon-beta therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge Clinical course and prognosis of Marburg virus (''green monkey'') disease Monovalent viruslike particle vaccine protects guinea pigs and nonhuman primates against infection with multiple Marburg viruses Vaccine to confer to nonhuman primates complete protection against multistrain Ebola and Marburg virus infections Marburg virus infection in nonhuman primates: therapeutic treatment by lipid-encapsulated siRNA Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA Advances in Virus-Like Particle Vaccines for Filoviruses Delayed time to treatment of an antisense morpholino oligomer is effective against lethal Marburg virus infection in cynomolgus macaques Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430 Ebola virus disease among children in West Africa Postexposure efficacy of recombinant vesicular stomatitis virus vectors against high and low doses of Marburg virus variant Angola in nonhuman primates


id: cord-255901-nl9k8uwd
author: Barasheed, Osamah
date: 2016-03-29
extension: .txt
mime: text/plain
words: 4523
sentence: 176
flesch: 42
cache: cache/cord-255901-nl9k8uwd.txt
txt: txt/cord-255901-nl9k8uwd.txt
title:
  Uptake and effectiveness of facemask against respiratory infections at mass gatherings: a systematic review

summary:
  key: cord-255901-nl9k8uwd authors: Barasheed, Osamah; Alfelali, Mohammad; Mushta, Sami; Bokhary, Hamid; Alshehri, Jassir; Attar, Ammar A.; Booy, Robert; Rashid, Harunor title: Uptake and effectiveness of facemask against respiratory infections at mass gatherings: a systematic review date: 2016-03-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2016.03.023 sha: doc_id: 255901 cord_uid: nl9k8uwd OBJECTIVES: The risk of acquisition and transmission of respiratory infections is high among attendees of mass gatherings (MGs).


id: cord-272179-wvw5mmy3
author: Calderaro, Adriana
date: 2020-10-02
extension: .txt
mime: text/plain
words: 1098
sentence: 35
flesch: 38
cache: cache/cord-272179-wvw5mmy3.txt
txt: txt/cord-272179-wvw5mmy3.txt
title:
  Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019-2020 in Parma, Northern Italy

summary:
  Coronavirus Disease Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan First two months of the 2019 Coronavirus Disease (COVID-19) epidemic in China: real-time surveillance and evaluation with a second derivative model Epidemiology of human respiratory viruses in children with acute respiratory tract infection in a 3-year hospital-based survey in Northern Italy Mammalian Diaphanous-related formin-1 restricts early phases of influenza A/NWS/33 virus (H1N1) infection in LLC-MK2 cells by affecting cytoskeleton dynamics Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research and Surveillance Centre primary care network: a cross-sectional study Coronaviruses and SARS-COV-2 Incidence and seasonality of respiratory viruses causing acute respiratory infections in the Northern United Arab Emirates Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children Viruses as Sole Causative Agents of Severe Acute Respiratory Tract Infections in Children Mixed respiratory virus infections Cresce la popolazione del Parmense 2019-nCoV (Wuhan virus), a novel Coronavirus: human-to-human transmission, travel-related cases, and vaccine readiness Etiology and clinical outcomes of acute respiratory virus infection in hospitalized adults The outbreak of SARS-CoV-2 pneumonia calls vaccines Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology Respiratory virus surveillance in hospitalised pneumonia patients on the Thailand-Myanmar border World Health Organization. This study aimed to determine the prevalence of respiratory virus infections, including SARS-CoV-2, during December 2019 – March 2020, in a tertiary care hospital-based survey in Parma (Northern Italy).


id: cord-259501-iggw1exl
author: Kim, Yong Yean
title: Acute Respiratory Illness in Rural Haiti
date: 2019-02-14
extension: .txt
mime: text/plain
words: 4626
sentence: 168
flesch: 47
cache: cache/cord-259501-iggw1exl.txt
txt: txt/cord-259501-iggw1exl.txt
summary:
  Younger children had FluA, HAdV and S. pneumoniae detected more often than older children, while S. aureus detection peaked in children with ages between the youngest and oldest age Groups. Percentage of school children with nasal swabs by school location, age, sex and month/year.


id: cord-261058-yu2qw02l
author: Burgner, David
title: Kawasaki disease: What is the epidemiology telling us about the etiology?
date: 2005-06-03
extension: .txt
mime: text/plain
words: 5150
sentence: 196
flesch: 30
cache: cache/cord-261058-yu2qw02l.txt
txt: txt/cord-261058-yu2qw02l.txt
summary:
  The value of isolated populations in genetic studies of allergic diseases Kawasaki disease in parents and children Kawasaki syndrome Kawasaki disease: review of risk factors for coronary aneurysms Coronary risks after high-dose gamma-globulin in children with Kawasaki disease Clinical relevance of the risk factors for coronary artery inflammation in kawasaki disease Coronary artery involvement in Kawasaki syndrome in Manhattan Cytokines predict coronary aneurysm formation in Kawasaki disease patients Raised serum interleukin 15 levels in Kawasaki disease Urinary neopterin as a predictive marker of coronary artery abnormalities in Kawasaki syndrome Genetic influence on cytokine production and fatal meningococcal disease Kawasaki disease: the mystery continues Increased frequency of alleles associated with elevated tumor necrosis factor-alpha levels in children with Kawasaki disease High incidence of angiotensin I converting enzyme genotype II in Kawasaki disease patients with coronary aneurysm Methylenetetrahydrofolate reductase polymorphism in Kawasaki disease HLA antigens in Kawasaki disease HLA antigens in mucocutaneous lymph node syndrome in New England Problems of reporting genetic associations with complex outcomes The HLA class II region and susceptibility to Kawasaki disease Polymorphism of transmembrane region of MICA gene and Kawasaki disease Polymorphism of SLC11A1 (formerly NRAMP1) gene confers susceptibility to Kawasaki disease Mapping disease genes: family-based association studies Control of confounding of genetic associations in stratified populations The TDT and other family-based tests for linkage disequilibrium and association Identification of susceptibility loci for insulindependent diabetes mellitus by trans-racial gene mapping The diagnosis and management of Kawasaki disease Adenovirus infection in patients with Kawasaki disease Could a herpesvirus be the cause of Kawasaki disease? Mycoplasma infection and Kawasaki disease Probable role of Streptococcus pyogenes in Kawasaki disease Serologic evidence that streptococcal superantigens are not involved in the pathogenesis of Kawasaki disease Variant Streptococcus sanguis as an etiological agent of Kawasaki disease Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome The absence of evidence of staphylococcal toxin involvement in the pathogenesis of Kawasaki disease Variant strain of Propionibacterium acnes: a clue to the etiology of Kawasaki disease Pathogenicity of Propionibacterium acnes isolated from Kawasaki disease patients-cytopathogenic protein (CPP) isolated from P. acnes culture filtrates and measurement of the antibody against CPP Positive Ehrlichia canis serology in Kawasaki disease Kawasaki disease in European adult associated with serological response to Coxiella burneti Role of house dust mites in Kawasaki disease Urine mercury levels in Kawasaki disease Rug shampoo and Kawasaki disease Association of rug shampooing and Kawasaki disease Clinical and epidemiologic characteristics of patients referred for evaluation of possible Kawasaki disease.


id: cord-262017-utvy0i8l
author: Tobar Vega, Pool
title: Talaromyces marneffei laboratory cross reactivity with Histoplasma and Blastomyces urinary antigen
date: 2019-06-21
extension: .txt
mime: text/plain
words: 1529
sentence: 66
flesch: 33
cache: cache/cord-262017-utvy0i8l.txt
txt: txt/cord-262017-utvy0i8l.txt
summary:
  In the U.S. patients with HIV infection usually undergo testing for endemic fungal infections such as Blastomyces, Histoplasma, Coccidioides and Paracoccidioides. His past medical history was relevant for HIV infection (since age 21) on HAART (bictegravir, emtricitabine & tenofovir alafenamide).


id: cord-254872-w6d397js
author: Stein, Richard A.
title: Methicillin-resistant Staphylococcus aureus—the new zoonosis
date: 2008-11-30
extension: .txt
mime: text/plain
words: 1672
sentence: 48
flesch: 20
cache: cache/cord-254872-w6d397js.txt
txt: txt/cord-254872-w6d397js.txt
summary:
  Low prevalence of methicillin resistant Staphylococcus aureus (MRSA) at hospital admission in the Netherlands: the value of search and destroy and restrictive antibiotic use Natural history of community-acquired methicillin-resistant Staphylococcus aureus colonization and infection in soldiers Community-acquired methicillin-resistant Staphylococcus aureus: prevalence and risk factors Community-acquired methicillin-resistant Staphylococcus aureus: a meta-analysis of prevalence and risk factors Influenza virus transmission: basic science and implications for the use of antiviral drugs during a pandemic 36 Host species barriers to influenza virus infections Catastrophes after crossing species barriers Emerging zoonoses: crossing the species barrier Influenza as a model system for studying the crossspecies transfer and evolution of the SARS coronavirus Food-initiated outbreak of methicillin-resistant Staphylococcus aureus analyzed by pheno-and genotyping Methicillin (oxacillin)-resistant Staphylococcus aureus strains isolated from major food animals and their potential transmission to humans Characterization of methicillin-resistant Staphylococcus aureus isolated from retail raw chicken meat in Japan Methicillin-resistant Staphylococcus aureus (MRSA) in foods of animal origin product in Italy Community-associated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis Proposed definitions of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) Trends in prescribing b-lactam antibiotics for treatment of communityacquired methicillin-resistant Staphylococcus aureus infections An outbreak of methicillin-resistant Staphylococcus aureus skin infections resulting from horse to human transmission in a veterinary hospital Suspected transmission of methicillin-resistant Staphylococcus aureus between domestic pets and humans in veterinary clinics and in the household Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs Antimicrobial resistance in pig faecal samples from the Netherlands (five abattoirs) and Sweden Increase in a Dutch hospital of methicillin-resistant Staphylococcus aureus related to animal farming Community-acquired MRSA and pig-farming Methicillinresistant Staphylococcus aureus in pig farming Presence of a novel DNA methylation enzyme in methicillin-resistant Staphylococcus aureus isolates associated with pig farming leads to uninterpretable results in standard pulsed-field gel electrophoresis analysis High prevalence of methicillin-resistant Staphylococcus aureus in pigs Methicillin-resistant Staphylococcus aureus colonization in pigs and pig farmers Human carriage of methicillinresistant Staphylococcus aureus linked with pet dog Human-to-dog transmission of methicillin-resistant Staphylococcus aureus Asymptomatic nasal carriage of mupirocin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) in a pet dog associated with MRSA infection in household contacts Methicillin-resistant Staphylococcus aureus (MRSA) isolated from animals and veterinary personnel in Ireland High risk for nasal carriage of methicillin-resistant Staphylococcus aureus among Danish veterinary practitioners Methicillin-resistant Staphylococcus aureus in veterinary doctors and students, the Netherlands Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel Evaluation of prevalence and risk factors for methicillin-resistant Staphylococcus aureus colonization in veterinary personnel attending an international equine veterinary conference MRSA in livestock animals--an epidemic waiting to happen?


id: cord-255021-acgfwjwi
author: Luo, Ying
date: 2020-05-01
extension: .txt
mime: text/plain
words: 597
sentence: 29
flesch: 54
cache: cache/cord-255021-acgfwjwi.txt
txt: txt/cord-255021-acgfwjwi.txt
title:
  Using the diagnostic model based on routine laboratory tests to distinguish patients infected with SARS-CoV-2 from those infected with influenza virus

summary:
  key: cord-255021-acgfwjwi authors: Luo, Ying; Yuan, Xu; Xue, Ying; Mao, Liyan; Lin, Qun; Tang, Guoxing; Song, Huijuan; Liu, Weiyong; Hou, Hongyan; Wang, Feng; Sun, Ziyong title: Using the diagnostic model based on routine laboratory tests to distinguish patients infected with SARS-CoV-2 from those infected with influenza virus date: 2020-05-01 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.04.078 sha: doc_id: 255021 cord_uid: acgfwjwi Abstract Background Although most results of routine laboratory tests between NCPP and IP had no significant difference, some laboratory tests showed an obvious change in NCPP.


id: cord-288167-976qxja2
author: Park, Wan Beom
date: 2018-05-09
extension: .txt
mime: text/plain
words: 1373
sentence: 57
flesch: 44
cache: cache/cord-288167-976qxja2.txt
txt: txt/cord-288167-976qxja2.txt
title:
  Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection

summary:
  In sputum and transtracheal aspirate, sub-genomic mRNA was detected for up to 4 weeks after symptoms developed, which correlated with the detection of genomic RNA. The objectives of this study were to examine the duration for detecting MERS-CoV sub-genomic mRNA vs. genomic RNA in different respiratory specimens.


id: cord-268599-z54p3dk3
author: Panda, Swagatika
title: Human metapneumovirus: review of an important respiratory pathogen
date: 2014-05-17
extension: .txt
mime: text/plain
words: 5574
sentence: 204
flesch: 30
cache: cache/cord-268599-z54p3dk3.txt
txt: txt/cord-268599-z54p3dk3.txt
summary:
  Mice Immunization induced complete protection against challenge with a homologous strain and cross-protective immunity against a heterologous strain 102 hRSV, human respiratory syncytial virus; SiRNA, small interfering RNA; IL, interleukin. Estimates of worldwide distribution of child deaths from acute respiratory infections Epidemiology of acute respiratory infections Human metapneumovirus: a new respiratory pathogen Epidemiological investigation of nine respiratory pathogens in hospitalized children in Germany using multiplex reverse transcriptase polymerase chain reaction A newly discovered human pneumovirus isolated from young children with respiratory tract disease Respiratory virus surveillance in hospitalised pneumonia patients on the Thailand-Myanmar border Human metapneumovirus associated with community-acquired pneumonia in children in Beijing PÃ© rez-BreÃ± a P. Two RT-PCR based assays to detect human metapneumovirus in nasopharyngeal aspirates Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children Antigenic and genetic variability of human metapneumoviruses Global genetic diversity of human metapneumovirus fusion gene Respiratory syncytial virus non-structural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness Respiratory infections by HMPV and RSV are clinically indistinguishable but induce different host response in aged individuals Frequent frame shift and point mutation in the SH gene of human metapneumovirus passaged in vitro Ten years of human metapneumovirus research Human metapneumovirus (HMPV) binding and infection are mediated by interactions between the HMPV fusion protein and heparan sulfate Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters Human metapneumovirus M2-2 protein inhibits innate cellular signalling by targeting MAVS Human metapneumovirus antagonism of innate immune responses Human metapneumovirus keeps dendritic cells from priming antigen-specific naive T cells Genomic analysis of four human metapneumovirus prototypes Detection of human bocavirus and human metapneumovirus by real-time PCR from patients with respiratory symptoms in Southern Brazil The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children Seasonal patterns of respiratory syncytial virus, influenza A virus, human metapneumovirus and parainfluenza virus type 3 on the basis of virus isolation data between Detection of human metapneumovirus in hospitalized children with acute respiratory tract infection using real-time RT-PCR in a hospital in northern Taiwan Epidemiology of human metapneumovirus Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups Human metapneumovirus infections in young and elderly adults A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections Fatal human metapneumovirus infection following allogeneic hematopoietic stem cell transplantation Detection of human metapneumovirus RNA sequences in nasopharyngeal aspirates of young French children with acute bronchiolitis by real-time reverse transcriptase PCR and phylogenetic analysis Respiratory tract re-infections by the new human metapneumovirus in an immunocompromised child Paediatric human metapneumovirus infection: epidemiology, prevention and therapy Differences in clinical severity between genotype A and genotype B human metapneumovirus infection in children Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade New vaccine surveillance network burden of human metapneumovirus infection in young children Molecular epidemiological investigation of a nosocomial outbreak of human metapneumovirus infection in a pediatric hemato-oncology patient population An outbreak of human metapneumovirus infection in hospitalized psychiatric adult patients in Taiwan Outbreaks of human metapneumovirus in two skilled nursing facilities-West Virginia and Idaho Human metapneumovirus in severe respiratory syncytial virus bronchiolitis Use of an innovative webbased laboratory surveillance platform to analyze mixed infections between human metapneumovirus (hMPV) and other respiratory viruses circulating in Alberta (AB) Impact of viral infections in children with community-acquired pneumonia: results of a study of 17 respiratory viruses Human metapneumovirus and community-acquired pneumonia in children Fatal human metapneumovirus and influenza B virus coinfection in an allogeneic hematopoietic stem cell transplant recipient Sero-epidemiology of human metapneumovirus (hMPV) on the basis of a novel enzyme-linked immunosorbent assay utilizing hMPV fusion protein expressed in recombinant vesicular stomatitis virus The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis Human metapneumovirus infection in young children hospitalized with respiratory tract disease Absence of human metapneumovirus co-infection in cases of severe respiratory syncytial virus infection Human metapneumovirus and severity of respiratory syncytial virus disease Human metapneumovirus infections in hospitalized children Characteristics of human metapneumovirus infection prevailing in hospital wards housing patients with severe disabilities Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients Association of human metapneumovirus with acute otitis media Metapneumovirus and acute wheezing in children Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults Detection of multiple viral and bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: a pilot prospective study Investigation of the presence of human metapneumovirus in patients with chronic obstructive pulmonary disease and asthma and its relationship with the attacks High prevalence of human metapneumovirus subtype B in cases presenting as severe acute respiratory illness: an experience at tertiary care hospital Human metapneumovirus associated with central nervous system infection in children Association between high nasopharyngeal viral load and disease severity in children with human metapneumovirus infection Analysis of viral load in children infected with human metapneumovirus Experimental infection of adults with recombinant wild-type human metapneumovirus Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and histopathological assessment Detection and characterisation of human metapneumovirus from children with acute respiratory symptoms in north-west England Clinical feature of different genotypes/genogroups of human metapneumovirus in hospitalized children The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice Differential production of inflammatory cytokines in primary infection with human metapneumovirus and with other common respiratory viruses of infancy Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis Human metapneumovirus RNA in encephalitis patient Studies of culture conditions and environmental stability of human metapneumovirus Human HepG2 cells support respiratory syncytial virus and human metapneumovirus replication Reproduction of the metapneumovirus in different cell lines Comparison of virus isolation using the Vero E6 cell line with rt RT-PCR assay for detection of hMPV Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses Seasonality and prevalence of respiratory pathogens detected by multiplex PCR at a tertiary care medical centre Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from Development of a multiplex one step RT PCR that detects eighteen respiratory viruses in clinical specimens in comparison with real time RT-PCR Detection of hMPV and RSV by duplex real time PCR assay in comparison with DFA Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro Treatment of severe human metapneumovirus pneumonia in an immunocompromised child with oral ribavirin and IVIG Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo Crossneutralization of four paramyxoviruses by a human monoclonal antibody Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus Inhibition of human metapneumovirus replication by small interfering RNA RNA interference in vitro and in vivo using Dsi RNA targeting the nucleocapsid N mRNA of human metapneumovirus Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3 0 proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques Virus like particle vaccine induces cross protection against human metapneumovirus infection in mice The use of plasmid-based reverse genetics to generate influenza virus strains for improved vaccine production Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates hMPV infection can cause severe bronchiolitis and pneumonia in children, and its symptoms are indistinguishable from those caused by human respiratory syncytial virus.


id: cord-257200-q0vqlerz
author: Zumla, A.
date: 2016-06-15
extension: .txt
mime: text/plain
words: 2508
sentence: 93
flesch: 44
cache: cache/cord-257200-q0vqlerz.txt
txt: txt/cord-257200-q0vqlerz.txt
title:
  What is the experience from previous mass gathering events? Lessons for Zika virus and the Olympics 2016

summary:
  These are not usually regarded as mass gathering events, but nevertheless they pose the same problem in terms of the transmission of pathogens in the situation of a large number of people in a limited space. One of the first events that focused the international health community on mass gathering events was the outbreak of meningitis in 2000-2001 after the Hajj.


id: cord-311413-uiwjrvru
author: Chanda-Kapata, Pascalina
title: COVID-19 and malaria: A symptom screening challenge for malaria endemic countries
date: 2020-04-27
extension: .txt
mime: text/plain
words: 1736
sentence: 56
flesch: 39
cache: cache/cord-311413-uiwjrvru.txt
txt: txt/cord-311413-uiwjrvru.txt
summary:
  Globally, all countries are at very high risk of COVID-19 while half of the world is at risk of malaria, with sub-Saharan countries bearing the blunt of malaria cases and deaths while South East Asia remain at high risk of both malaria and COVID-19 (WHO, 2020b,c). Since malaria tests are relatively more available (Landier et al., 2016) , we recommend that health workers perform rapid tests for malaria as they screen for COVID-19.


id: cord-261672-0cresfn8
author: Kim, Sungchan
title: Evaluation of COVID-19 epidemic outbreak caused by temporal contact-increase in South Korea
date: 2020-05-14
extension: .txt
mime: text/plain
words: 1637
sentence: 78
flesch: 53
cache: cache/cord-261672-0cresfn8.txt
txt: txt/cord-261672-0cresfn8.txt
summary:
  key: cord-261672-0cresfn8 authors: Kim, Sungchan; Jeong, Yong Dam; Byun, Jong Hyuk; Cho, Giphil; Park, Anna; Jung, Jae Hun; Roh, Yunil; Choi, Sooyoun; Muhammad, Ibrahim Malik; Jung, Il Hyo title: Evaluation of COVID-19 epidemic outbreak caused by temporal contact-increase in South Korea date: 2020-05-14 journal: In this study, we establish a mathematical model using the early data of confirmed cases that were reported from January 20 to March 15 in Korea.


id: cord-266253-oyid5haj
author: Al-Abaidani, I.S.
date: 2014-10-29
extension: .txt
mime: text/plain
words: 1113
sentence: 41
flesch: 45
cache: cache/cord-266253-oyid5haj.txt
txt: txt/cord-266253-oyid5haj.txt
title:
  Overview of preparedness and response for Middle East respiratory syndrome coronavirus (MERS-CoV) in Oman

summary:
  The surveillance system for severe acute respiratory infections (SARI) was implemented in Oman in January 2008 in four regional hospitals as sentinel sites; SARI aims to determine the epidemiology of severe respiratory infections and the contribution of influenza and other etiological agents to severe respiratory infections in the country. Strengthened infection control practices and having a powerful active surveillance program for acute respiratory illnesses is key to the rapid and prompt response for emerging respiratory infections.


id: cord-275866-m89hgf41
author: Li, Ping
title: Clinical Features and Short-term Outcomes of Elderly Patients With COVID-19
date: 2020-05-31
extension: .txt
mime: text/plain
words: 2361
sentence: 107
flesch: 49
cache: cache/cord-275866-m89hgf41.txt
txt: txt/cord-275866-m89hgf41.txt
summary:
  The onset of dyspnea might help physicians identify the patients with poor prognosis.35.3% patients were classified as severe or even critical cases on admission. Although so far the overall mortality of COVID-19 is relatively low, the mortality of elderly patients is much higher.


id: cord-274845-pqvlh3eg
author: Li, Yan
date: 2020-05-07
extension: .txt
mime: text/plain
words: 1347
sentence: 58
flesch: 50
cache: cache/cord-274845-pqvlh3eg.txt
txt: txt/cord-274845-pqvlh3eg.txt
title:
  Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing

summary:
  key: cord-274845-pqvlh3eg authors: Li, Yan; Wang, Jiangshan; Wang, Chunting; Yang, Qiwen; Xu, Yingchun; Xu, Jun; Li, Yi; Yu, Xuezhong; Zhu, Huadong; Liu, Jihai title: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing date: 2020-05-07 journal: Conclusions Influenza viruses accounted for a large proportion of respiratory virus infection even during the epidemic of COVID-19 in Beijing.


id: cord-262310-z0m6uuzf
author: Effenberger, Maria
title: Association of the COVID-19 pandemic with Internet Search Volumes: A Google TrendsTM Analysis
date: 2020-04-17
extension: .txt
mime: text/plain
words: 2775
sentence: 100
flesch: 51
cache: cache/cord-262310-z0m6uuzf.txt
txt: txt/cord-262310-z0m6uuzf.txt
summary:
  In addition, Google Trends TM data might be used to forecast an increase in infected cases. Retrieving Google Trends TM data on COVID-19 The Google Trends TM tool was used to retrieve data on internet user search activities in the context of COVID-19.


id: cord-305788-z75yv88e
author: Agergaard, Charlotte Nielsen
date: 2020-09-28
extension: .txt
mime: text/plain
words: 733
sentence: 33
flesch: 50
cache: cache/cord-305788-z75yv88e.txt
txt: txt/cord-305788-z75yv88e.txt
title:
  Challenging diagnostics in familial transmission from asymptomatic COVID-19 carrier. Should we group SARS-CoV-2 samples from households?

summary:
  A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster A pandemic in times of global tourism: super spreading and exportation of COVID-19 cases from a ski area in Austria Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France Immunity after SARS-CoV-2 infection, 1st update -a rapid review 2020 SSI. key: cord-305788-z75yv88e authors: Agergaard, Charlotte Nielsen; Lis-Tønder, Joanna; Olsen, Dorte Aalund; Kierkegaard, Helene; Møller, Jens Kjølseth title: Challenging diagnostics in familial transmission from asymptomatic COVID-19 carrier.


id: cord-276254-q04hqra2
author: Paul, Kishor Kumar
date: 2020-06-02
extension: .txt
mime: text/plain
words: 3830
sentence: 140
flesch: 42
cache: cache/cord-276254-q04hqra2.txt
txt: txt/cord-276254-q04hqra2.txt
title:
  Comparing insights from clinic-based versus community-based outbreak investigations: a case study of chikungunya in Bangladesh

summary:
  Inference from community cases plus controls from same household J o u r n a l P r e -p r o o f Incorporating controls from the households where cases reside allowed us to assess additional potential risk factors for being a case. The epidemic curve was constructed using symptom onset date of chikungunya cases.


id: cord-257073-dm80bxnd
author: Akmatov, Manas K.
date: 2011-08-17
extension: .txt
mime: text/plain
words: 3518
sentence: 148
flesch: 42
cache: cache/cord-257073-dm80bxnd.txt
txt: txt/cord-257073-dm80bxnd.txt
title:
  E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology

summary:
  The non-responder survey allowed us to compare prospectively (participants) and retrospectively (non-responders) collected data on acute respiratory infection symptoms, and it revealed that the prospective approach resulted in a higher rate of detection of mild infections. key: cord-257073-dm80bxnd authors: Akmatov, Manas K.; Krebs, Stephan; Preusse, Matthias; Gatzemeier, Anja; Frischmann, Ursula; Schughart, Klaus; Pessler, Frank title: E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology date: 2011-08-17 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2011.07.005 sha: doc_id: 257073 cord_uid: dm80bxnd OBJECTIVE: We examined the feasibility of combining communication by e-mail and self-collection of nasal swabs for the prospective detection of acute respiratory infections in a non-medical setting.


id: cord-275250-ilmgy7ce
author: Xia, Yong
title: Dynamics of antibodies to SARS-CoV-2 in a case with SARS-CoV-2 infection
date: 2020-05-17
extension: .txt
mime: text/plain
words: 730
sentence: 33
flesch: 55
cache: cache/cord-275250-ilmgy7ce.txt
txt: txt/cord-275250-ilmgy7ce.txt
summary:
  On Feb 17, reactivity to IgG antibody was significantly positive, but reactivity to IgM antibody was still weak by using Kit A. Reactivity to IgM antibody was obviously positive by using Kit B. IgM and IgG antibody levels were 0.74 AU/mL, 6.90 AU/mL, respectively. As shown in Table 1 , on Feb 14, reactivity to IgM/ IgG antibodies was very weak and invisible to the naked eye by using Kit A, C. Reactivity to IgM antibody was positive and visible to the naked eye by using Kit B. IgM and IgG antibodies had been assayed by using Kit D, and IgM and IgG antibody levels were 0.62 AU/mL, 2.41 AU/mL, respectively (normal IgM and IgG <1.1 AU/mL).


id: cord-280627-dfnc9g2c
author: Wang, Xiong
date: 2020-04-18
extension: .txt
mime: text/plain
words: 1847
sentence: 79
flesch: 46
cache: cache/cord-280627-dfnc9g2c.txt
txt: txt/cord-280627-dfnc9g2c.txt
title:
  Comparison of nasopharyngeal and oropharyngeal swabs for SARS-CoV-2 detection in 353 patients received tests with both specimens simultaneously

summary:
  Two consecutively negative RT-PCR test results in respiratory tract specimens is required for the evaluation of discharge from hospital, and oropharyngeal swabs were the most common sample. Higher positive rate (positive tests/total tests) was observed in nasopharyngeal swabs than oropharyngeal swabs, especially in inpatients.


id: cord-275191-lgze4zex
author: Al-Sadeq, Duaa W.
title: The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: a systematic review
date: 2020-07-02
extension: .txt
mime: text/plain
words: 3294
sentence: 142
flesch: 40
cache: cache/cord-275191-lgze4zex.txt
txt: txt/cord-275191-lgze4zex.txt
summary:
  medRxiv COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals 18 F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases Comparative serological study for the prevalence of anti-MERS coronavirus antibodies in high-and low-risk groups in Qatar A serological assay to detect SARS-CoV-2 seroconversion in humans The relative transmissibility of asymptomatic COVID-19 infections among close contacts Almost 75% of people on board Diamond Princess with COVID-19 may have been asymptomatic Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship It worth mentioning that there is a high percent of COVID-19 asymptomatic patients who could transmit the infection to all communities.


id: cord-305782-gnzwe2z2
author: Satici, Celal
date: 2020-06-14
extension: .txt
mime: text/plain
words: 3390
sentence: 139
flesch: 49
cache: cache/cord-305782-gnzwe2z2.txt
txt: txt/cord-305782-gnzwe2z2.txt
title:
  Performance of Pneumonia Severity Index and CURB-65 in Predicting 30-day mortality in patients with COVID-19

summary:
  A prospective cohort study Correlation between the variables collected at admission and progression to severe cases during hospitalization among COVID-19 patients in Chongqing 30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: a prospective cohort study Characteristics and circumstances of falls in a hospital setting: A prospective analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Albumin and C-reactive protein have prognostic significance in patients with community-acquired pneumonia Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19 CURB 65 score as a predictor of early mortality in hospital-acquired pneumonia Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting C-reactive protein levels in the early stage of COVID-19 WHO Novel Coronavirus (2019-nCoV) situation report Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Prediction models for diagnosis and prognosis of covid-19 infection: Systematic review and critical appraisal An interpretable mortality prediction model for COVID-19 patients Analysis of 92 deceased patients with COVID-19 D-dimer levels on admission to predict inhospital mortality in patients with Covid-19 Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Essential psychological problems of hospitalized patients II or III versus IV or V. Abbreviations: CI: confidence interval, PPV: positive predictive values, NPV: negative predictive values, AUC: area under curve In conclusion, this single center retrospective study including a large cohort of COVID-19 patients showed that PSI is a powerful tool to predict mortality in patients with COVID-19.


id: cord-303417-1237ykxt
author: d’Arminio Monforte, Antonella
title: Effectiveness of Hydroxychloroquine in COVID-19 disease: A done and dusted situation?
date: 2020-07-29
extension: .txt
mime: text/plain
words: 660
sentence: 23
flesch: 39
cache: cache/cord-303417-1237ykxt.txt
txt: txt/cord-303417-1237ykxt.txt
summary:
  J o u r n a l P r e -p r o o f Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalised with COVID-19 Hydroxycholoroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomised clinical trial Hydroxychloroquine in patients mainly with mild to moderate COVID-19: an open-label, randomised, controlled trial An observational cohort study of hydroxychloroquine and azithromycin for COVID-19: (Can't get no) satisfaction Effect of desamethasone in hospitalized patients with CVID-19: preliminary report. key: cord-303417-1237ykxt authors: d’Arminio Monforte, Antonella; Tavelli, Alessandro; Bai, Francesca; Marchetti, Giulia; Cozzi-Lepri, Alessandro title: Effectiveness of Hydroxychloroquine in COVID-19 disease: A done and dusted situation? date: 2020-07-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.07.056 sha: doc_id: 303417 cord_uid: 1237ykxt nan


id: cord-292092-o6s5nw49
author: Furuse, Yuki
date: 2015-09-30
extension: .txt
mime: text/plain
words: 1233
sentence: 51
flesch: 52
cache: cache/cord-292092-o6s5nw49.txt
txt: txt/cord-292092-o6s5nw49.txt
title:
  Conservation of nucleotide sequences for molecular diagnosis of Middle East respiratory syndrome coronavirus, 2015

summary:
  The numbers of viral sequences that matched the primer/ probe sequences perfectly were counted. In addition, viral sequences of the reverse primer region for the NSeq assay were not highly conserved; the sequence matched only 49% of strains.


id: cord-282421-yialyuav
author: Alcoba-Florez, Julia
title: Sensitivity of different RT-qPCR solutions for SARS-CoV-2 detection
date: 2020-08-01
extension: .txt
mime: text/plain
words: 1051
sentence: 36
flesch: 41
cache: cache/cord-282421-yialyuav.txt
txt: txt/cord-282421-yialyuav.txt
summary:
  Thus, we are confident that the differences in sensitivity among solutions were due to their different components (i.e. primers-sets, buffers, enzymes and reagent contents in general). That of best sensitivity was also assessed with direct nasopharyngeal swab viral transmission medium (VTM) heating, overcoming the RNA extraction step.


id: cord-293942-n5ypkftc
author: Takoi, Hiroyuki
title: Favipiravir-induced fever in coronavirus disease 2019: A report of two cases
date: 2020-09-28
extension: .txt
mime: text/plain
words: 1163
sentence: 63
flesch: 50
cache: cache/cord-293942-n5ypkftc.txt
txt: txt/cord-293942-n5ypkftc.txt
summary:
  A definition of drug fever is a disorder characterized by fever coinciding with the administration of a drug and disappearing after the discontinuation of the drug, when no other cause for the fever is evident after a careful physical examination and laboratory investigation, with a period of 1.3 ± 1.1 days from discontinuation of the causative drug to pyretolysis (Makowiak and LeMaistre, 1987) . Drug fever can be ruled out if pyretolysis is not confirmed within 72 h after the discontinuation of the drug (Mourad et al., 2003) .


id: cord-278406-n5e3a09i
author: Macauley, Precious
date: 2020-08-21
extension: .txt
mime: text/plain
words: 1495
sentence: 35
flesch: 15
cache: cache/cord-278406-n5e3a09i.txt
txt: txt/cord-278406-n5e3a09i.txt
title:
  CORTICOSTEROIDS IN THE TREATMENT OF SEVERE COVID-19 LUNG DISEASE: THE PULMONOLOGY PERSPECTIVE FROM THE FIRST UNITED STATES EPICENTER

summary:
  While caring for scores of severe COVID-19 lung disease patients and repeatedly witnessing a striking clinicoradiographic response to pulse corticosteroids, we were disheartened by the initial negativity towards corticosteroids expressed by, among others, our infectious disease colleagues (Massachusetts General Hospital, 2020; the use of corticosteroids in pulmonary medicine, including at pulse dose, for certain diffuse lung diseases, a practice that is readily applied even to novel entities such as e-cigarette or vaping product-use associated lung injury (EVALI) that lack any evidence base (Layden et al, 2020) . It is worth considering that corticosteroids were administered based on clinicians' discretion a median of three days into ICU stay at a median dose in methylprednisolone equivalents of 60mg, very different from the one gram of methylprednisolone starting on the day of ICU arrival and continued for three days that has been our practice with severe COVID-19 lung disease.


id: cord-276445-m5vjo3ym
author: Lee, Hyojung
title: Recrudescence of Ebola virus disease outbreak in West Africa, 2014–2016
date: 2017-09-20
extension: .txt
mime: text/plain
words: 1639
sentence: 67
flesch: 48
cache: cache/cord-276445-m5vjo3ym.txt
txt: txt/cord-276445-m5vjo3ym.txt
summary:
  Subsequently, the country without EVD cases would enter a period of heightened surveillance lasting 90 days to monitor for any other occurrence of infection. Sierra Leone reports second new Ebola case CDC's Response to the 2014-2016 Ebola epidemic -Guinea Related Ebola cases in Guinea and Liberia Ebola RNA persistence in semen of Ebola virus disease survivors -preliminary report Female survivor may be cause of Ebola flare-up in Liberia.


id: cord-283812-ocfjj79v
author: Blumberg, Lucille
date: 2016-06-15
extension: .txt
mime: text/plain
words: 2836
sentence: 96
flesch: 39
cache: cache/cord-283812-ocfjj79v.txt
txt: txt/cord-283812-ocfjj79v.txt
title:
  Hosting of mass gathering sporting events during the 2013–2016 Ebola virus outbreak in West Africa: experience from three African countries

summary:
  European Football Championship Finals: planning for a health legacy Olympic and Paralympic Games: public health surveillance and epidemiology Hajj: infectious disease surveillance and control Global perspectives for prevention of infectious diseases associated with mass gatherings Communicable diseases as health risks at mass gatherings other than Hajj: what is the evidence? Ebola virus diseases outbreak Rapid spread of Zika virus in the Americas-implications for public health preparedness for mass gatherings at the 2016 Brazil Olympic Games Yellow fever cases in Asia: primed for an epidemic Why is the yellow fever outbreak in Angola a 'threat to the entire world'?


id: cord-292988-q1yz9y8k
author: Zumla, Alimuddin
date: 2020-05-17
extension: .txt
mime: text/plain
words: 3163
sentence: 89
flesch: 21
cache: cache/cord-292988-q1yz9y8k.txt
txt: txt/cord-292988-q1yz9y8k.txt
title:
  Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy - achieving global consensus and visibility for cellular host-directed therapies

summary:
  Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma Primary Analysis of a Phase 1/2 Study to Assess MultiStem® Cell Therapy, a Regenerative Advanced Therapy Medicinal Product (ATMP), in Acute Respiratory Distress Syndrome (MUST-ARDS) Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Design and validation of a consistent and reproducible manufacture process for the production of clinical-grade bone marrow-derived multipotent mesenchymal stromal cells Prospects and progress in cell therapy for acute respiratory distress syndrome Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement Mesenchymal stem cells together with mycophenolate mofetil inhibit antigen presenting cell and T cell infiltration into allogeneic heart grafts Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities Effects of mesenchymal stem cells transplantation on cognitive deficits in animal models of Alzheimer's disease: A systematic review and meta-analysis Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis Are mesenchymal stromal cells immune cells Mesenchymal Stromal Cells Anno 2019:


id: cord-268883-nf4fm7r7
author: Corchuelo, Jairo
title: Oral manifestations in a patient with a history of asymptomatic COVID-19. Case Report
date: 2020-09-01
extension: .txt
mime: text/plain
words: 1681
sentence: 52
flesch: 35
cache: cache/cord-268883-nf4fm7r7.txt
txt: txt/cord-268883-nf4fm7r7.txt
summary:
  Oral candida infection has been reported to almost always involve a locally or systemically compromised host (Zegarelli 1993) . Together, these agents explain the melanin pigmentation that is sometimes seen in association with inflammatory conditions of the skin or oral mucosa (Satomura et al. 2007 ).


id: cord-308080-1heu9vuv
author: Simulundu, Edgar
date: 2020-10-06
extension: .txt
mime: text/plain
words: 1714
sentence: 59
flesch: 40
cache: cache/cord-308080-1heu9vuv.txt
txt: txt/cord-308080-1heu9vuv.txt
title:
  First COVID-19 Case in Zambia – Comparative phylogenomic analyses of SARS-CoV-2 detected in African countries

summary:
  Ethical review and approval to publish: Ethical approval for case study and phylogenomic sequencing, and publication of this case study was obtained from the University of Zambia positive only in the case under study. Whilst African countries were relatively spared initially, the initial low incidence of COVID-19 cases was not sustained for long due to continuing travel links between China, Europe and Africa..


id: cord-280060-gzby85u9
author: Rello, Jordi
date: 2016-04-28
extension: .txt
mime: text/plain
words: 5495
sentence: 223
flesch: 32
cache: cache/cord-280060-gzby85u9.txt
txt: txt/cord-280060-gzby85u9.txt
title:
  Management of infections in critically ill returning travellers in the intensive care unit—II: clinical syndromes and special considerations in immunocompromised patients()

summary:
  Travel patterns and risk behavior in solid organ transplant recipients International travel patterns and travel risks for stem cell transplant recipients International travel in the immunocompromised patient: a cross-sectional survey of travel advice in 254 consecutive patients Symptoms of infectious diseases in immunocompromised travelers: a prospective study with matched controls Multidrug-resistant bacteria without borders: role of international trips in the spread of multidrug-resistant bacteria Infection in solid-organ transplant recipients Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients Travel medicine and transplant tourism in solid organ transplantation Hematopoietic stem cell transplantation: an overview of infection risks and epidemiology Rates of serious infection, including site-specific and bacterial intracellular infection, in rheumatoid arthritis patients receiving anti-tumor necrosis factor therapy: results from the British Society for Rheumatology Biologics Register Tuberculosis associated with infliximab, a tumor necrosis factor alphaneutralizing agent Anti-tumour necrosis factor-induced visceral and cutaneous leishmaniasis: case report and review of the literature Bacterial infections in low-risk, febrile neutropenic patients Post-splenectomy and hyposplenic states Such patients may be instructed to start empirical antibiotics targeted at encapsulated bacteria immediately if any clinical signs or symptoms of infection ensue.


id: cord-279976-juz9jnfk
author: Xie, Mingxuan
date: 2020-04-01
extension: .txt
mime: text/plain
words: 3921
sentence: 143
flesch: 42
cache: cache/cord-279976-juz9jnfk.txt
txt: txt/cord-279976-juz9jnfk.txt
title:
  Insight into 2019 novel coronavirus — an updated intrim review and lessons from SARS-CoV and MERS-CoV

summary:
  JAMA 2020a Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Decoding the evolution and transmissions of the novel pneumonia coronavirus (SARS-CoV-2) using whole genomic data Summary of probable SARS cases with onset of illness from 1 WHO . MedRxiv(preprint) 2020 MERS transmission and risk factors: a systematic review Lung pathology and pathogenesis of severe acute respiratory syndrome: a report of six full autopsies A report on the general observation of a 2019 novel coronavirus autopsy Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.


id: cord-290206-fmy4zrim
author: Lim, Jue Tao
title: The Costs of an Expanded Screening Criteria for COVID-19: A Modelling Study
date: 2020-08-12
extension: .txt
mime: text/plain
words: 4216
sentence: 142
flesch: 38
cache: cache/cord-290206-fmy4zrim.txt
txt: txt/cord-290206-fmy4zrim.txt
summary:
  The cost framework examined the impact of the ESC on hospitalization and testing costs while considering the transmission dynamics and importation rates of COVID-19 cases in a hospital setting. The net cost of ESC is calculated as the total hospitalization costs for the isolation of negative patients subtracted from the total hospitalization costs averted from the isolation of positive cases which would have otherwise been missed by a non ESC criteria.


id: cord-273961-ja8xggnd
author: Nakagawara, Kensuke
date: 2020-07-26
extension: .txt
mime: text/plain
words: 786
sentence: 31
flesch: 47
cache: cache/cord-273961-ja8xggnd.txt
txt: txt/cord-273961-ja8xggnd.txt
title:
  Acute Onset Olfactory/Taste Disorders are Associated with a High Viral Burden in Mild or Asymptomatic SARS-CoV-2 Infections

summary:
  Specifically, Ct values from qPCR tests conducted on nasopharyngeal or sputum specimens of patients on admission were negatively associated with disease severity and progression to severe illness, and mild patients showed an early viral clearance using Ct values (1, 2) . We retrospectively assessed the association between symptoms and Ct values or the period to negative qPCR.


id: cord-024631-yvek5vjz
author: Althaus, T.
date: 2020-05-11
extension: .txt
mime: text/plain
words: 4330
sentence: 164
flesch: 35
cache: cache/cord-024631-yvek5vjz.txt
txt: txt/cord-024631-yvek5vjz.txt
title:
  Causes of fever in primary care in Southeast Asia and the performance of C-reactive protein in discriminating bacterial from viral pathogens

summary:
  We thank all primary care patients and health workers from Chiang Rai primary care centres and Hlaing Tha Yar public hospital and MAM clinics for taking part in the study. C-reactive protein (CRP) is one of the most studied host-response biomarkers of bacterial infection, consistently showing high sensitivity and moderate specificity, and CRP POCTs have been shown to be cost-effective in resource-poor environments


id: cord-287209-hkrarxsd
author: Zhao, Shi
date: 2020-02-20
extension: .txt
mime: text/plain
words: 957
sentence: 39
flesch: 57
cache: cache/cord-287209-hkrarxsd.txt
txt: txt/cord-287209-hkrarxsd.txt
title:
  The basic reproduction number of novel coronavirus (2019-nCoV) estimation based on exponential growth in the early outbreak in China from 2019 to 2020: A reply to Dhungana

summary:
  Other teams either used retrospective dataset which was not publicly available on January 23, 2020 or used oversea reported cases which was not (to a much less extent) affected by the changes in reporting rate. The estimates on the basic reproduction number, R0, were carried out in early outbreak as of January 22, 2020 when the surveillance data and the knowledge on the key epidemiological features of 2019-nCoV were limited.


id: cord-268389-0agwvsrv
author: Kaminski, Monica A.
title: Tocilizumab Therapy of COVID-19: A Comparison of Subcutaneous and Intravenous Therapies
date: 2020-09-28
extension: .txt
mime: text/plain
words: 3416
sentence: 116
flesch: 36
cache: cache/cord-268389-0agwvsrv.txt
txt: txt/cord-268389-0agwvsrv.txt
summary:
  More patients in the IV group received Supportive treatment with tocilizumab for COVID-19: A systematic review Clinical outcomes in COVID-19 patients treated with tocilizumab: An individual patient data systematic review Consider IL6 receptor antagonist for the therapy of cytokine storm syndrome in SARS-CoV-2 infected patients Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China Detectable serum SARS-Co-V-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort Tocilizumab in patients with severe COVID-19: a retrospective cohort study Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients FDA approval summary: tocilizumab for treatment of chimeric antigen receptor T Cell-induced severe or life-threatening cytokine release syndrome Current concepts in the diagnosis and management of cytokine release syndrome Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19. At the time of IV tocilizumab therapy, 36 (55%) patients met grade 3 and 27 (42%)


id: cord-293247-ltxt2dfv
author: Elachola, Habida
date: 2015-10-09
extension: .txt
mime: text/plain
words: 1234
sentence: 36
flesch: 32
cache: cache/cord-293247-ltxt2dfv.txt
txt: txt/cord-293247-ltxt2dfv.txt
title:
  Advancing the global health security agenda in light of the 2015 annual Hajj pilgrimage and other mass gatherings

summary:
  Although current GHSA is yet to specifically highlight mass gathering preparedness as a strategic priority even in countries with high participant contribution to mass gatherings, the 12 Global Health Security Agenda action packages and the strategies to minimize the implications of mass gathering on public health are similar. Mass gatherings offer opportunities to implement, test, and assess GHSA objectives in its entirety and can contribute significantly to health security of individuals, nations, and the world.


id: cord-310691-6danlh8h
author: Ma, Simin
date: 2020-05-26
extension: .txt
mime: text/plain
words: 2298
sentence: 90
flesch: 46
cache: cache/cord-310691-6danlh8h.txt
txt: txt/cord-310691-6danlh8h.txt
title:
  Clinical Characteristics of Critically Ill Patients Co-infected with SARS-CoV-2 and the Influenza Virus in Wuhan, China

summary:
  The results showed a high proportion of COVID-19 patients were co-infected with influenza in Tongji Hospital, with no significant difference in the proportion of co-infection between survivors and non-survivors. Studies have reported that elevated D-dimer levels are a risk factor for death in COVID-19 patients (Wu et al. 2020a; Zhou et al. 2020) .


id: cord-304872-hnxmtbrf
author: Lv, Hao
date: 2020-09-17
extension: .txt
mime: text/plain
words: 3437
sentence: 157
flesch: 51
cache: cache/cord-304872-hnxmtbrf.txt
txt: txt/cord-304872-hnxmtbrf.txt
title:
  Prevalence and recovery time of olfactory and gustatory dysfunctions of hospitalized patients with COVID‑19 in Wuhan, China

summary:
  Patients with COVID-19 and OD and/or GD had significantly higher rates of cardiovascular disease than patients without OD and/or GD (p = 0.002). Patients under 18 years of age, patients with a history of cognitive disorders, and patients with OD and/or GD known before the epidemic.


id: cord-311654-ixn65hxb
author: Zumla, Alimuddin
date: 2020-08-08
extension: .txt
mime: text/plain
words: 1419
sentence: 36
flesch: 33
cache: cache/cord-311654-ixn65hxb.txt
txt: txt/cord-311654-ixn65hxb.txt
title:
  COVID-19 and the scaled-down 2020 Hajj Pilgrimage - Decisive, logical and prudent decision making by Saudi authorities overcomes pre-Hajj public health concerns

summary:
  WHO with global MG partners, developed comprehensive key recommendations for COVID-19, and since end of February, 2020, there was a stepwise increase in cancellation, temporary suspension or postponement of international and national religious, sporting, musical, and other MGs, as countries worldwide took public health and other measures (WHO, 2020b; McCloskey et al, 2020; Petersen, McCloskey et al, 2020) . In early June 2020, after careful consideration, the Saudi government took decisive, logical, logistical and prudent decisions (Saudi Ministry of Hajj and Umrah, 2020) to overcome these pre-Hajj nightmares of public health, political, economic and religious concerns.


id: cord-291367-rtmsrh16
author: Zumla, Alimuddin
date: 2015-07-02
extension: .txt
mime: text/plain
words: 2263
sentence: 69
flesch: 36
cache: cache/cord-291367-rtmsrh16.txt
txt: txt/cord-291367-rtmsrh16.txt
title:
  Middle East Respiratory Syndrome - need for increased vigilance and watchful surveillance for MERS-CoV in sub-Saharan Africa

summary:
  -Saudi Arabia The Hajj pilgrimage and surveillance for Middle East Respiratory syndrome coronavirus in pilgrims from African countries High prevalence of common respiratory viruses and no evidence of Middle East Respiratory Syndrome Coronavirus in Hajj pilgrims returning to Ghana Hajj: infectious disease surveillance and control Travel implications of emerging coronaviruses: SARS and MERS-CoV Etiology of severe community-acquired pneumonia during the 2013 Hajj-part of the MERS-CoV surveillance program An update on Middle East respiratory syndrome: 2 years later Pilgrims and MERS-CoV: what's the risk? KSA MERS-CoV Investigation Team. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description Middle East Respiratory Syndromeadvancing the public health and research agenda on MERS-lessons from the South Korea outbreak Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers Infection prevention and control of epidemic-and pandemicprone acute respiratory infections in health care -WHO Guidelines.


id: cord-273090-fdzkfo1u
author: He, Susu
title: Relationship between Chest CT manifestations and immune response in COVID-19 patients
date: 2020-06-20
extension: .txt
mime: text/plain
words: 2841
sentence: 115
flesch: 54
cache: cache/cord-273090-fdzkfo1u.txt
txt: txt/cord-273090-fdzkfo1u.txt
summary:
  There were 72 (77%) patients with elevated IL-6, of which 42 were in mild patients (70% of the mild group) and 30 were in severe patients (91% of the severe group). Among them, severe patients had much more chances of consolidation than mild patients, which was statistically different ( Table 3) .


id: cord-282360-byqhzyzi
author: Zhang, Dingmei
title: Enterovirus 71 vaccine: close but still far
date: 2010-04-18
extension: .txt
mime: text/plain
words: 4412
sentence: 159
flesch: 33
cache: cache/cord-282360-byqhzyzi.txt
txt: txt/cord-282360-byqhzyzi.txt
summary:
  We reviewed publications on the development of EV71 vaccines in order to provide an overview of the field. To develop EV71 vaccines with a high protection efficacy, strategies such as the use of adjuvant, strong promoters, tissue-specific promoters, and addition of mucosal immune adjuvant should be considered.


id: cord-311479-8pjoz64q
author: He, Daihai
title: The relative transmissibility of asymptomatic cases among close contacts
date: 2020-04-18
extension: .txt
mime: text/plain
words: 815
sentence: 36
flesch: 49
cache: cache/cord-311479-8pjoz64q.txt
txt: txt/cord-311479-8pjoz64q.txt
summary:
  We remark that how efficient of the transmissibility of asymptomatic cases comparing 130 to symptomatic cases warrants more study. To the best of our knowledge, this is the first time the relative transmissibility of asymptomatic COVID-19 cases is quantified.


id: cord-279892-37vyazby
author: Sun, Guanghao
date: 2017-01-16
extension: .txt
mime: text/plain
words: 2904
sentence: 111
flesch: 40
cache: cache/cord-279892-37vyazby.txt
txt: txt/cord-279892-37vyazby.txt
title:
  Remote sensing of multiple vital signs using a CMOS camera-equipped infrared thermography system and its clinical application in rapidly screening patients with suspected infectious diseases

summary:
  healthcare settings Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport A novel screening method for influenza patients using a newly developed non-contact screening system An infectious disease/fever screening radar system which stratifies higher-risk patients within ten seconds using a neural network and the fuzzy grouping method Multiple vital-sign based infection screening outperforms thermography independent of the classification algorithm A novel infection screening method using a neural network and k-means clustering algorithm which can be applied for screening of unknown or unexpected infectious diseases Non-contact measurement of respiratory and heart rates using a CMOS camera-equipped infrared camera for prompt infection screening at airport quarantine stations Advancements in noncontact, multiparameter physiological measurements using a webcam Dimension reduction-based penalized logistic regression for cancer classification using microarray data Clinical tests: sensitivity and specificity Characteristics of infectious diseases in hospitalized patients during the early phase after the 2011 great East Japan earthquake: pneumonia as a significant reason for hospital care Infectious diseases following natural disasters: prevention and control measures Monitoring of influenza viruses in the aftermath of the great East Japan earthquake This work was supported by a Grant-in-Aid for Young Scientists (grant number 16K16363) that was funded by the Japanese Ministry of Education, Culture, Sports, Science and Technology. key: cord-279892-37vyazby authors: Sun, Guanghao; Nakayama, Yosuke; Dagdanpurev, Sumiyakhand; Abe, Shigeto; Nishimura, Hidekazu; Kirimoto, Tetsuo; Matsui, Takemi title: Remote sensing of multiple vital signs using a CMOS camera-equipped infrared thermography system and its clinical application in rapidly screening patients with suspected infectious diseases date: 2017-01-16 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2017.01.007 sha: doc_id: 279892 cord_uid: 37vyazby BACKGROUND:


id: cord-259837-5tbdqzxr
author: Kalcioglu, Mahmut Tayyar
title: May COVID-19 cause sudden sensorineural hearing loss?
date: 2020-09-29
extension: .txt
mime: text/plain
words: 519
sentence: 19
flesch: 45
cache: cache/cord-259837-5tbdqzxr.txt
txt: txt/cord-259837-5tbdqzxr.txt
summary:
  key: cord-259837-5tbdqzxr authors: Kalcioglu, Mahmut Tayyar; Cag, Yasemin; Kilic, Osman; Tuysuz, Ozan title: May COVID-19 cause sudden sensorineural hearing loss? date: 2020-09-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.09.1468 sha: doc_id: 259837 cord_uid: 5tbdqzxr nan We thank to Pietro D L et al for their comments on our recently published article (Kilic et al., 2020) . In previous studies, viral infections have been reported to have an important role in the etiology of sudden sensorineural hearing loss (SSNHL) (Cohen et al., 2014) .


id: cord-302409-40ktyt5q
author: Wang, Jie
date: 2020-04-18
extension: .txt
mime: text/plain
words: 2772
sentence: 121
flesch: 44
cache: cache/cord-302409-40ktyt5q.txt
txt: txt/cord-302409-40ktyt5q.txt
title:
  SARS-CoV-2 RNA detection of hospital isolation wards hygiene monitoring during the Coronavirus Disease 2019 outbreak in a Chinese hospital

summary:
  key: cord-302409-40ktyt5q authors: Wang, Jie; Feng, Haiting; Zhang, Sheng; Ni, Zuowei; Ni, Lingmei; Chen, Yu; Zhuo, Lixin; Zhong, Zifeng; Qu, Tingting title: SARS-CoV-2 RNA detection of hospital isolation wards hygiene monitoring during the Coronavirus Disease 2019 outbreak in a Chinese hospital date: 2020-04-18 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.04.024 sha: doc_id: 302409 cord_uid: 40ktyt5q OBJECTIVES: The aim of this paper was to monitor the presence of SARS-Cov-2 among hospital environment surfaces, sewage, and personal protective equipment (PPE) of staffs in isolation wards in the First Affiliated Hospital of Zhejiang University, China.


id: cord-316209-juvmabdq
author: Rutayisire, Erigene
title: What works and what does not work in response to COVID-19 prevention and control in Africa
date: 2020-06-12
extension: .txt
mime: text/plain
words: 2337
sentence: 81
flesch: 46
cache: cache/cord-316209-juvmabdq.txt
txt: txt/cord-316209-juvmabdq.txt
summary:
  Since the last brief on May 26 th from Africa CDC, the number of COVID-19 cases has increased by 32% (37096 cases), this shows the burden COVID-19 could impose on African countries. If the cases continue to increase, many African countries will not be able to manage those cases; there is a need for international cooperation to reduce the burden this disease will impose on African countries.


id: cord-320785-42p8292o
author: Lobo, Andréa de Paula
title: COVID-19 epidemic in Brazil: where we at?
date: 2020-06-16
extension: .txt
mime: text/plain
words: 682
sentence: 31
flesch: 60
cache: cache/cord-320785-42p8292o.txt
txt: txt/cord-320785-42p8292o.txt
summary:
  Joinpoint regression models were applied to identify points of inflection in COVID-19 trends, considering the days since the 50th confirmed case as time unit. Method ecological time-series based on cumulative confirmed cases of COVID-19 from March 11 to May 12.


id: cord-311026-mpr3xb2a
author: Petersen, Eskild
title: COVID-19–We urgently need to start developing an exit strategy
date: 2020-04-29
extension: .txt
mime: text/plain
words: 5634
sentence: 261
flesch: 51
cache: cache/cord-311026-mpr3xb2a.txt
txt: txt/cord-311026-mpr3xb2a.txt
summary:
  A study comparing health care systems in Hong Kong, Singapore and Japan had three important conclusions [Legido-Quigley et al. 2020 ]. Over half of the non-imported cases could be traced back to their close contacts with reported local cases.


id: cord-257265-lkzytud0
author: Zheng, Fang
date: 2020-08-03
extension: .txt
mime: text/plain
words: 4191
sentence: 152
flesch: 43
cache: cache/cord-257265-lkzytud0.txt
txt: txt/cord-257265-lkzytud0.txt
title:
  SARS-CoV-2 Clearance in COVID-19 Patients with Novaferon Treatment: A Randomized, Open-label, Parallel Group Trial

summary:
  So far, only limited observations of Lopinavir/Ritonavir for coronavirus in SARS patients were reported (Chu et al.,2004) .A The peak levels of SARS virus were around 10 days after onset and then the viral level J o u r n a l P r e -p r o o f began to decrease without effective antiviral treatment in SARS patients (Peiris et al., 2003) .Considering the homology of gene sequences of SARS-CoV-2 and SARS was over 90% (Zhu et al., 2020) , we assumed that the intervention of antiviral drugs in COVID-19 patients would likely enhance or shorten the time to viral clearance.


id: cord-306200-d5qn65k0
author: Petersen, Eskild
date: 2020-04-17
extension: .txt
mime: text/plain
words: 1470
sentence: 49
flesch: 42
cache: cache/cord-306200-d5qn65k0.txt
txt: txt/cord-306200-d5qn65k0.txt
title:
  COVID-19 travel restrictions and the International Health Regulations – call for an open debate on easing of travel restrictions

summary:
  Whilst travel restriction measures that significantly interfere with international traffic may be justified at the beginning of an outbreak, since they allow countries time to implement effective preparedness measures based on careful risk assessment, they should be based on a reasoned scientific evaluation of the available evidence on their possible effectiveness. key: cord-306200-d5qn65k0 authors: Petersen, Eskild; McCloskey, Brian; Hui, David S; Kock, Richard; Ntoumi, Francine; Memish, Ziad A; Kapata, Nathan; Azhar, Esam I; Pollack, Marjorie; Madoff, Larry C.; Hamer, Davidson H; Nachega, Jean B; Pshenichnaya, N.; Zumla, Alimuddin title: COVID-19 travel restrictions and the International Health Regulations – call for an open debate on easing of travel restrictions date: 2020-04-17 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.04.029 sha: doc_id: 306200 cord_uid: d5qn65k0 nan Correspondence:


id: cord-338225-8dlxnpcn
author: De Meyer, Sandra
title: Lack of Antiviral Activity of Darunavir against SARS-CoV-2
date: 2020-05-29
extension: .txt
mime: text/plain
words: 331
sentence: 11
flesch: 42
cache: cache/cord-338225-8dlxnpcn.txt
txt: txt/cord-338225-8dlxnpcn.txt
summary:
  Overall, the data do not support use of darunavir for treatment of COVID-19 CoV-2]), human immunodeficiency virus (HIV) protease inhibitors are being considered as 23 therapeutic alternatives. Results DRV showed no activity against SARS-CoV-2 at clinically relevant concentrations (EC50 >100μM).


id: cord-309032-idjdzs97
author: Zhou, Feng
date: 2020-10-09
extension: .txt
mime: text/plain
words: 4177
sentence: 157
flesch: 44
cache: cache/cord-309032-idjdzs97.txt
txt: txt/cord-309032-idjdzs97.txt
title:
  Epidemiological Characteristics and Factors Associated with Critical Time Intervals of COVID-19 in Eighteen Provinces, China: A Retrospective Study

summary:
  Among the patients who were clearly exposed to confirmed cases, imported cases had more contacts with other confirmed cases than local cases on average, and contacts were mainly family members. Results Among 7,042 cases, 3392 (48.17%) were local cases and 3304 (46.92%) were imported cases.


id: cord-293630-zc8huo1j
author: Capone, Alessandro
date: 2020-08-05
extension: .txt
mime: text/plain
words: 2160
sentence: 87
flesch: 41
cache: cache/cord-293630-zc8huo1j.txt
txt: txt/cord-293630-zc8huo1j.txt
title:
  Simultaneous circulation of COVID-19 and flu in Italy: potential combined effects on the risk of death?

summary:
  Demographic and clinical characteristics of died patients (including the number of comorbidities) are extremely relevant, especially to define those with a higher risk of mortality. Demographic and clinical characteristics of died patients (including the number of comorbidities) are extremely relevant, especially to define those with a higher risk of mortality.


id: cord-317080-kn56oov6
author: Quadri, Sayed. A.
title: COVID-19 and Religious Congregations: Implications for Spread of Novel Pathogens
date: 2020-05-07
extension: .txt
mime: text/plain
words: 291
sentence: 17
flesch: 52
cache: cache/cord-317080-kn56oov6.txt
txt: txt/cord-317080-kn56oov6.txt
summary:
  COVID 19 is spread through droplet and basic reproduction rate, a 23 measure of transmissibility of the virus, ranges from 2.24 to 3.58 (Zhao et al., 2020) . The refusal to suspend such gatherings could lead to potential widespread dispersal of infections.


id: cord-320829-uepneyug
author: He, Zhongping
date: 2005-08-10
extension: .txt
mime: text/plain
words: 2632
sentence: 94
flesch: 50
cache: cache/cord-320829-uepneyug.txt
txt: txt/cord-320829-uepneyug.txt
title:
  Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets

summary:
  In Table 3 the lymphocyte subpopulation counts were compared between those with severe SARS (260 samples from 149 patients), non-severe SARS (436 samples from 122 patients), and those that recovered (613 samples from 246 cases) or died (48 samples from 25 patients) from SARS. The total lymphocyte counts from SARS patients were compared with those from normal individuals, and the lymphocyte counts at each week after the onset of the illness were compared with other weeks of illness and with those from normal individuals.


id: cord-320860-qt84oicg
author: Zhang, Aining
date: 2020-09-15
extension: .txt
mime: text/plain
words: 2363
sentence: 85
flesch: 37
cache: cache/cord-320860-qt84oicg.txt
txt: txt/cord-320860-qt84oicg.txt
title:
  Meta-Analysis of coagulation parameters associated with disease severity and poor prognosis of COVID-19

summary:
  The unique characteristics of COVID-19 coagulopathy Development of a critical appraisal tool to assess the quality of cross-sectional studies (AXIS) Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19 Correlation Between Relative Nasopharyngeal Virus RNA Load and Lymphocyte Count Disease Severity in Patients with COVID Clinical features and treatment of COVID-19 patients in northeast Chongqing Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Epidemiological, clinical and virological characteristics of 74 cases of coronavirus Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Prominent changes in blood coagulation of patients with SARS-CoV-2 infection Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis PPIs and Beyond: A Framework for Managing Anticoagulation-Related Gastrointestinal Bleeding in the Era of COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Conclusions Our data support the notion that coagulopathy could be considered as a risk factor for disease severity and mortality of COVID-19, which may help clinicians to identify the incidence of poor outcomes in COVID-19 patients.


id: cord-318315-r6wqywwe
author: Memish, Ziad A.
date: 2014-06-23
extension: .txt
mime: text/plain
words: 3093
sentence: 143
flesch: 45
cache: cache/cord-318315-r6wqywwe.txt
txt: txt/cord-318315-r6wqywwe.txt
title:
  Etiology of severe community-acquired pneumonia during the 2013 Hajj—part of the MERS-CoV surveillance program

summary:
  The etiology of severe pneumonia is complex and includes the newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV). Since 2012, the Saudi Ministry of Health (MoH) has required screening for MERS-CoV for all cases of severe pneumonia requiring hospitalization.


id: cord-323696-0lq8ql6n
author: Bearman, Gonzalo
title: Reflections on the COVID-19 Pandemic in the USA: Will We Better Prepared Next Time?
date: 2020-05-20
extension: .txt
mime: text/plain
words: 1856
sentence: 102
flesch: 46
cache: cache/cord-323696-0lq8ql6n.txt
txt: txt/cord-323696-0lq8ql6n.txt
summary:
  Public health systems must be adequately funded and staffed to address both present and future infectious diseases threats. The fragmentation, disparities in care and misaligned incentives do not provide a strong foundation for public health emergencies.


id: cord-316505-tdlj5smv
author: Kumar, Abhai
date: 2013-11-28
extension: .txt
mime: text/plain
words: 4499
sentence: 183
flesch: 43
cache: cache/cord-316505-tdlj5smv.txt
txt: txt/cord-316505-tdlj5smv.txt
title:
  Proteomics-based identification of plasma proteins and their association with the host–pathogen interaction in chronic typhoid carriers

summary:
  (b) Graphical representation of the percentage volume changes of spot expression in the control, acute typhoid cases, and chronic typhoid carriers groups; *p < 0.05 for controls vs. chronic typhoid carriers, and # p < 0.05 for acute typhoid cases vs. chronic typhoid carriers in the case of spot 1 (proprotein convertase subtilisin); *p < 0.05 for controls vs. chronic typhoid carriers, and # p < 0.05 for acute typhoid cases vs. chronic typhoid carriers in the case of spot 2 (furin); **p < 0.01 for controls vs. chronic typhoid carriers, and ## p < 0.01 for acute typhoid cases vs. chronic typhoid carriers in the case of spot 3 (haptoglobin); *p < 0.05 for controls vs. chronic typhoid carriers, and # p < 0.05 for acute typhoid cases vs. chronic typhoid carriers in the case of spot 4 (albumin). METHODS: Proteomics-based studies were done to determine the expression of differentially expressed proteins in the plasma of controls, acute typhoid cases, and chronic typhoid carriers.


id: cord-334603-yt2pmxi3
author: de Sousa, Eric
date: 2020-07-18
extension: .txt
mime: text/plain
words: 1797
sentence: 41
flesch: 15
cache: cache/cord-334603-yt2pmxi3.txt
txt: txt/cord-334603-yt2pmxi3.txt
title:
  Mortality in COVID-19 disease patients: Correlating Association of Major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 (SARS-CoV-2) variants

summary:
  A Systematic review DRB1*03/DRB3*0101, and DRB3*0202 are susceptibility genes for Graves' disease in North American Caucasians, whereas DRB1*07 is protective E6 and E7 Gene Polymorphisms in Human Papillomavirus Types-58 and 33 Identified in Southwest China Multiple sclerosis and autoimmune diseases: epidemiology and HLA-DR association in North-east Italy Analysis of HLA DP, DQ, and DR allesles in adult Italian rheumatoid arthritis patients Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan Association of HLA-DRB3*0202 and serum IgG antibodies to Chlamydia pneumoniae with essential hypertension in a highly homogeneous population from Majorca Molecular analysis of HLA class IIassociated susceptibility to neuroinflammatory diseases in Korean children HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis Professor Ippolito, Sir Zumla and Prof Mohamed Osman are co-investigators investigators of the Pan-African Network on Emerging and Re-emerging Infections (PANDORA-ID-NET) funded by the European and Developing Countries Clinical Trials Partnership the EU Horizon 2020 Framework Programme for Research and Innovation. Is ethnicity linked to incidence or outcomes of covid-19? Association of HLA class I with severe acute respiratory syndrome coronavirus infection Association of human-leukocyteantigen class I (B*0703) and class II (DRB1*0301) genotypes with susceptibility and resistance to the development of severe acute respiratory syndrome Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection Black/white differences in leukocyte subpopulations in men HLA studies in the context of coronavirus outbreaks Guillain-Barre syndrome associated with SARS-CoV-2 infection: causality or coincidence? Association between human leukocyte antigen-DR and demylinating Guillain-Barre syndrome The MHC locus and genetic susceptibility to autoimmune and infectious diseases Genetics of the HLA region in the prediction of type 1 diabetes Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profile DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele


id: cord-317624-qdzhncs0
author: Choi, Min Joo
date: 2020-10-27
extension: .txt
mime: text/plain
words: 4289
sentence: 150
flesch: 39
cache: cache/cord-317624-qdzhncs0.txt
txt: txt/cord-317624-qdzhncs0.txt
title:
  Comparison of antiviral effect for mild-to-moderate COVID-19 cases between lopinavir/ritonavir versus hydroxychloroquine: A nationwide propensity score-matched cohort study

summary:
  Nationwide retrospective case-control study was conducted to compare the effect of HCQ and LPV/r on viral shedding duration among patients with mild-to-moderate COVID-19 using the reimbursement data of National Health Insurance Service. Among these, only mild-to-moderate grade 1 patients were included in the analysis, and the effect of LPV/r or HCQ use on viral shedding duration was evaluated ( Figure 1 ).


id: cord-326881-3j2e92dj
author: Vassallo, M.
date: 2020-09-28
extension: .txt
mime: text/plain
words: 2388
sentence: 89
flesch: 36
cache: cache/cord-326881-3j2e92dj.txt
txt: txt/cord-326881-3j2e92dj.txt
title:
  Patients with Covid-19 exhibit different immunological profiles according to their clinical presentation

summary:
  Conclusions In a population of elderly patients recently infected with Covid-19, CD10 + B cell levels were inversely correlated with clinical severity. Qin et al. found lower levels of helper T cells and suppressor T cells in severe patients, but demographic characteristics of severe and non-severe patients were significantly different


id: cord-340279-bq5owwot
author: Espíndola, Otávio de Melo
date: 2020-06-04
extension: .txt
mime: text/plain
words: 286
sentence: 10
flesch: 31
cache: cache/cord-340279-bq5owwot.txt
txt: txt/cord-340279-bq5owwot.txt
title:
  Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid

summary:
  4 • Common neuropathogens should be investigated in the CSF of COVID-19 patients. key: cord-340279-bq5owwot authors: Espíndola, Otávio de Melo; Siqueira, Marilda; Soares, Cristiane Nascimento; Lima, Marco Antonio Sales Dantas de; Leite, Ana Claudia Celestino Bezerra; Araujo, Abelardo Queiroz Campos; Brandão, Carlos Otávio; Silva, Marcus Tulius Teixeira title: Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid date: 2020-06-04 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.05.123 sha: doc_id: 340279 cord_uid: bq5owwot


id: cord-292256-jp80u828
author: Moriguchi, Takeshi
title: A first case of meningitis/encephalitis associated with SARS-Coronavirus-2
date: 2020-04-03
extension: .txt
mime: text/plain
words: 1746
sentence: 83
flesch: 47
cache: cache/cord-292256-jp80u828.txt
txt: txt/cord-292256-jp80u828.txt
summary:
  In 2002-2003, Severe Acute Respiratory Syndrome (SARS) pandemic appeared and SARS-CoV was isolated as the pathogen and as the new family of the human coronaviruses (Drosten et al., 2003; Ksiazek et al., 2003) . Recent study claims that the genomic sequence is similar between SARS-CoV and SARS-CoV-2 (Yu et al., 2020) , especially the receptor-binding domains of SARS-CoV is structurally similar to that of SARS-CoV-2 (Lu et al., 2020) .


id: cord-315059-l6guql8q
author: Mubarak, Naeem
date: 2020-04-30
extension: .txt
mime: text/plain
words: 477
sentence: 21
flesch: 61
cache: cache/cord-315059-l6guql8q.txt
txt: txt/cord-315059-l6guql8q.txt
title:
  Corona and Clergy: The missing link for an effective social distancing in Pakistan. Time for some unpopular decisions

summary:
  [of] us, coming days would be more challenging 45 for Pakistan to implement social distancing in the holy month of Ramadan (26 th April) when 46 influx in mosques increases many-fold for daily prayers and Tarawih (an additional prayer in 47 Author has no conflict of interest and source of funding to disclose for this manuscript. In Pakistan, the practice of social distancing 24 An evaluation version of novaPDF was used to create this PDF file.


id: cord-315860-9j667c03
author: Jullien, Sophie
date: 2020-04-10
extension: .txt
mime: text/plain
words: 5635
sentence: 244
flesch: 41
cache: cache/cord-315860-9j667c03.txt
txt: txt/cord-315860-9j667c03.txt
title:
  Pneumonia in children admitted to the national referral hospital in Bhutan: A prospective cohort study

summary:
  Nevertheless, these findings confirm the low yield of blood culture in hospitalized children with pneumonia and question both the need of blood culture for uncomplicated cases of pneumonia and using blood culture as the preferred screening tool for invasive bacterial disease in children with pneumonia. key: cord-315860-9j667c03 authors: Jullien, Sophie; Pradhan, Dinesh; Tshering, Tashi; Sharma, Ragunath; Dema, Kumbu; Garcia-Garcia, Selene; Ribó, Jose Luis; Muñoz-Almagro, Carmen; Bassat, Quique title: Pneumonia in children admitted to the national referral hospital in Bhutan:


id: cord-326143-6ndqgxy8
author: Wang, Qiang
date: 2020-05-26
extension: .txt
mime: text/plain
words: 1328
sentence: 60
flesch: 52
cache: cache/cord-326143-6ndqgxy8.txt
txt: txt/cord-326143-6ndqgxy8.txt
title:
  Successful recovery of severe COVID-19 with cytokine storm treating with extracorporeal blood purification

summary:
  (198.66 pg/ml) was almost 10 folds of normal range (≤5.9 pg/ml) which indicated an initiation of cytokine storm on day 12 ( Figure 1 ). He got fever on day 1 (February 14, 2020) and had chill, headache, muscle soreness, fatigue, nausea, cough, and chest distress and shortness of breath on day 3.


id: cord-336954-rh88lod0
author: Shim, Eunha
title: Transmission potential and severity of COVID-19 in South Korea
date: 2020-03-18
extension: .txt
mime: text/plain
words: 2977
sentence: 96
flesch: 43
cache: cache/cord-336954-rh88lod0.txt
txt: txt/cord-336954-rh88lod0.txt
summary:
  Euro surveillance : bulletin Europeen sur les maladies transmissibles Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions Real-time forecasts of the COVID-19 epidemic in China from Surge in South Korea virus cases linked to church 'super-spreader'. Next, to estimate the most recent estimate of Rt, we simulate the progression of incident cases from GGM, and apply the discretized probability distribution ( ) of the generation interval using the renewal equation (H. Nishiura, 2009 , Nishiura and Chowell, 2014 , Paine et al., 2010 given by In the renewal equation we denote the local incidence at calendar time by , and the raw incidence J o u r n a l P r e -p r o o f of imported cases at calendar time by .


id: cord-257737-obadq502
author: Wu, Di
title: Positive effects of COVID-19 control measures on influenza prevention
date: 2020-04-10
extension: .txt
mime: text/plain
words: 355
sentence: 12
flesch: 57
cache: cache/cord-257737-obadq502.txt
txt: txt/cord-257737-obadq502.txt
summary:
  According to the Chinese National Influenza Center, ILI activity (ILI%) in 2020 in South China was lower than that in North China from week 5 to week 10, and this situation reversed in the subsequent 2 weeks; in contrast, in 2019, ILI% was constantly higher in South China than in North China for the first 11 weeks (except for the first week of 2019) ( Figure 1A ) [ Figure 1 here] Guangzhou City, in South China, has also seen a relatively higher ILI% over Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention WHO.


id: cord-297829-aynigoud
author: Zhang, Li
date: 2014-04-13
extension: .txt
mime: text/plain
words: 3323
sentence: 144
flesch: 47
cache: cache/cord-297829-aynigoud.txt
txt: txt/cord-297829-aynigoud.txt
title:
  Post-pandemic assessment of public knowledge, behavior, and skill on influenza prevention among the general population of Beijing, China

summary:
  There were significant differences in health literacy level related to influenza among the different gender, age, educational level, occupational status, and location groups (p < 0.05). There were significant differences in health literacy level related to influenza among the different gender, age, educational level, occupational status, and location groups (p < 0.05).


id: cord-311453-l6quzef6
author: Klopfenstein, Timothée
date: 2020-08-13
extension: .txt
mime: text/plain
words: 2680
sentence: 113
flesch: 49
cache: cache/cord-311453-l6quzef6.txt
txt: txt/cord-311453-l6quzef6.txt
title:
  Impact of Tocilizumab on mortality and/or invasive mechanical ventilation requirement in a cohort of 206 COVID-19 patients

summary:
  Patients in TCZ group seemed to be more severe than patients in ST group. The tocilizumab group (TCZ group) included all patients (except patients already in intensive care unit with IMV) whom received standard treatment and TCZ (8mg/kg per dose, 1 or 2 doses).


id: cord-301085-tk2vvxj7
author: Askarian, Mehrdad
date: 2006-07-11
extension: .txt
mime: text/plain
words: 2611
sentence: 99
flesch: 35
cache: cache/cord-301085-tk2vvxj7.txt
txt: txt/cord-301085-tk2vvxj7.txt
title:
  Knowledge, attitude, and practices related to standard precautions of surgeons and physicians in university-affiliated hospitals of Shiraz, Iran

summary:
  These findings illustrate that SP practices are not behaviors readily adopted, even by those aware of the SP issue and moderate to low levels of attitudes. Our poor compliance with many SP practices is not unique to our teaching hospitals, with similar results published in other centers.


id: cord-318181-xxc7vdnt
author: Ahmed, Anwar E.
date: 2018-03-14
extension: .txt
mime: text/plain
words: 4390
sentence: 150
flesch: 43
cache: cache/cord-318181-xxc7vdnt.txt
txt: txt/cord-318181-xxc7vdnt.txt
title:
  Early identification of pneumonia patients at increased risk of Middle East respiratory syndrome coronavirus infection in Saudi Arabia

summary:
  Accuracy and cost comparison in medical testing using sequential testing strategies Reducing cost in sequential testing: a limit of indifference approach Believe the extreme (BE) strategy at the optimal point: what strategy will it become Diagnostic delays in 537 symptomatic cases of Middle East respiratory syndrome coronavirus infection in Saudi Arabia Estimating survival rates in MERS-CoV patients 14 and 45 days after experiencing symptoms and determining the differences in survival rates by demographic data, disease characteristics and regions: a worldwide study The predictors of 3-and 30-day mortality in 660 MERS-CoV patients MERS-CoV diagnosis: an update The critical care response to a hospital outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection: an observational study Middle East respiratory syndrome coronavirus: a case-control study of hospitalized patients Outbreak of Middle East respiratory syndrome coronavirus in Saudi Arabia: a retrospective study Risk factors for primary Middle East respiratory syndrome coronavirus illness in humans Laboratory testing for Middle East respiratory syndrome coronavirus (MERS-CoV) Case definition and surveillance guidance -updated Critically ill patients with the Middle East respiratory syndrome: a multicenter retrospective cohort study Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Detection of the Middle East respiratory syndrome coronavirus genome in an air sample originating from a camel barn owned by an infected patient Evidence for camel-to-human transmission of MERS coronavirus Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis Clinical presentation and outcomes of Middle East Respiratory Syndrome in the Republic of Korea Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction Combining biomarkers to detect disease with application to prostate cancer Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, 2015: epidemiology, characteristics and public health implications Predictors of MERS-CoV infection: a large case control study of patients presenting with ILI at a MERS-CoV referral hospital in Saudi Arabia Epidemiological investigation of Middle East respiratory syndrome coronavirus in dromedary camel farms linked with human infection in Abu Dhabi Emirate MERS-CoV outbreak in Jeddah-a link to health care facilities Combining diagnostic test results to increase accuracy MERS-CoV geography and ecology in the Middle East: analyses of reported camel exposures and a preliminary risk map Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia On the principles of believe the positive and believe the negative for diagnosis using two continuous tests Middle East respiratory syndrome coronavirus in Al-Madinah City, Saudi Arabia: Demographic, clinical and survival data Emerging molecular markers of cancer Linear combinations of multiple diagnostic markers Comparative evaluation of three homogenization methods for isolating Middle East key: cord-318181-xxc7vdnt authors: Ahmed, Anwar E.; Al-Jahdali, Hamdan; Alshukairi, Abeer N.; Alaqeel, Mody; Siddiq, Salma S.; Alsaab, Hanan; Sakr, Ezzeldin A.; Alyahya, Hamed A.; Alandonisi, Munzir M.; Subedar, Alaa T.; Aloudah, Nouf M.; Baharoon, Salim; Alsalamah, Majid A.; Al Johani, Sameera; Alghamdi, Mohammed G. title: Early identification of pneumonia patients at increased risk of Middle East respiratory syndrome coronavirus infection in Saudi Arabia date: 2018-03-14 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2018.03.005 sha: doc_id: 318181 cord_uid: xxc7vdnt BACKGROUND: The rapid and accurate identification of individuals who are at high risk of Middle East respiratory syndrome coronavirus (MERS-CoV) infection remains a major challenge for the medical and scientific communities.


id: cord-277640-vy7ex5lv
author: Calderaro, Adriana
date: 2020-05-14
extension: .txt
mime: text/plain
words: 1177
sentence: 36
flesch: 38
cache: cache/cord-277640-vy7ex5lv.txt
txt: txt/cord-277640-vy7ex5lv.txt
title:
  SARS-CoV-2 infection diagnosed only by cell culture isolation before the local outbreak in an Italian seven-week-old suckling baby

summary:
  To the best of our knowledge, no literature evidence of SARS-CoV-2 virus infection diagnosed including virus isolation is present for suckling babies and very little evidence for new-borns (Lu and Shi, 2020, Wang et al., 2020); in these reported cases, laboratory diagnosis was only done by molecular methods. To the best of our knowledge, in the international literature at the time of the manuscript submission, no other reports of infants of this age describing the laboratory diagnosis of SARS-CoV-2 infection including virus isolation together with RNA detection were present.


id: cord-300774-5mrkmctl
author: Hernández-Mora, Miguel Górgolas
title: Compassionate Use of Tocilizumab in Severe SARS-CoV2 Pneumonia
date: 2020-10-25
extension: .txt
mime: text/plain
words: 4339
sentence: 166
flesch: 42
cache: cache/cord-300774-5mrkmctl.txt
txt: txt/cord-300774-5mrkmctl.txt
summary:
  We provided tocilizumab on a compassionate-use basis to patients with SSP hospitalized (excluding intensive care and intubated cases) who required oxygen support to have a saturation >93%. Patients received at least one dose of 400 mg intravenous tocilizumab during March 8-2020, through April 20-2020.


id: cord-344478-5gp7v1uh
author: Rosenberg, Eli S.
date: 2020-07-29
extension: .txt
mime: text/plain
words: 762
sentence: 31
flesch: 42
cache: cache/cord-344478-5gp7v1uh.txt
txt: txt/cord-344478-5gp7v1uh.txt
title:
  Clarifying the record on hydroxychloroquine for the treatment of patients hospitalized with COVID-19

summary:
  Arshad et al study [7] . June 15 decision to revoke hydroxychloroquine's Emergency Use Authorization (EUA) for COVID-19 treatment


id: cord-317500-ufo2qgj4
author: Scialpi, Michele
title: Pulmonary thromboembolism in criticall ill COVID-19 patients
date: 2020-04-24
extension: .txt
mime: text/plain
words: 431
sentence: 9
flesch: 11
cache: cache/cord-317500-ufo2qgj4.txt
txt: txt/cord-317500-ufo2qgj4.txt
summary:
  Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT 2019-novel Coronavirus severe adult respiratory distress syndrome in two cases in Italy: An uncommon radiological presentation Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Acute pulmonary embolism and COVID-19 pneumonia: a random association? COVID-19 Complicated by Acute Pulmonary Embolism Radiology: TH Open Management strategy of novel coronavirus (COVID-19) pneumonia in the radiology department: a Chinese experience The Authors declare no conflicts of interest associated for the manuscript entiltled Pulmonary thromboembolism in criticall ill COVID-19 patients


id: cord-317910-rwhwo55z
author: Aziz, Asma B.
title: Integrated control of COVID-19 in resource poor countries
date: 2020-09-09
extension: .txt
mime: text/plain
words: 2436
sentence: 94
flesch: 41
cache: cache/cord-317910-rwhwo55z.txt
txt: txt/cord-317910-rwhwo55z.txt
summary:
  COVID-19 vaccine trials should seek worthwhile efficacy A win-win solution? Oxford team begins vaccine trials in Brazil and South Africa to determine efficacy World Health Organization Solidarity Vaccines Trial Expert Group.


id: cord-308114-68cgub5o
author: Afrin, Lawrence B.
title: Covid-19 Hyperinflammation and Post-Covid-19 Illness May Be Rooted in Mast Cell Activation Syndrome
date: 2020-09-10
extension: .txt
mime: text/plain
words: 3459
sentence: 90
flesch: 25
cache: cache/cord-308114-68cgub5o.txt
txt: txt/cord-308114-68cgub5o.txt
summary:
  r o o f summarize the evidence suggesting that mast cell activation disease, the majority of which is constituted by the prevalent, but only recently recognized, mast cell activation syndrome (MCAS), fits very well with these enigmatic findings. J o u r n a l P r e -p r o o f Mast cell-orchestrated immunity to pathogens A concise, practical guide to diagnostic assessment for mast cell activation disease Mast cell activation disease: An underappreciated cause of neurologic and psychiatric symptoms and diseases Often seen, rarely recognized: mast cell activation disease -a guide to diagnosis and therapeutic options Mast cell activation disease and the modern epidemic of chronic inflammatory disease Mast Cell Regulatory Gene Variants Are Common in Mast Cell Activation Syndrome Characterization of Mast Cell Activation Syndrome Diagnosis of mast cell activation syndrome: a global consensus-2 The biology of Kit in disease and the application of pharmacogenetics The association between obesity and poor outcome after COVID-19 indicates a potential therapeutic role for montelukast Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Epidemiology of COVID-19 Clinical characteristics of 113 deceased patients with coronavirus disease 2019:


id: cord-320902-1hfxju5f
author: Filocamo, Giovanni
title: Use of anakinra in severe COVID-19: a case report
date: 2020-05-11
extension: .txt
mime: text/plain
words: 1442
sentence: 51
flesch: 34
cache: cache/cord-320902-1hfxju5f.txt
txt: txt/cord-320902-1hfxju5f.txt
summary:
  While the former accounts for 80% of cases, severe disease with acute respiratory distress syndrome (ARDS) and critical disease with respiratory failure and/or multiple organ dysfunction are diagnosed in 15-30% and 5% of COVID-19 patients, respectively (1). To date, May the 5th 2020, 12 clinical trials on anakinra in COVID-19 patients are registered on ClinicalTrials.gov, 7 of them recruiting patients.


id: cord-328459-nmd81sue
author: Dioscoridi, Lorenzo
title: Covid-19 exposure risk for family members of healthcare workers: an observational study
date: 2020-07-04
extension: .txt
mime: text/plain
words: 1244
sentence: 58
flesch: 54
cache: cache/cord-328459-nmd81sue.txt
txt: txt/cord-328459-nmd81sue.txt
summary:
  All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Study population derived from a high-volume COVID-19 hospital of Milan, Italy.


id: cord-325325-xw7627x9
author: Skeik, Nedaa
title: Influenza viruses and the evolution of avian influenza virus H5N1
date: 2007-10-02
extension: .txt
mime: text/plain
words: 4082
sentence: 184
flesch: 45
cache: cache/cord-325325-xw7627x9.txt
txt: txt/cord-325325-xw7627x9.txt
summary:
  Although the risk of transmission from person Influenza viruses and the evolution of avian influenza virus H5N1 to person appears low, quarantining of close contacts to patients for a week after last exposure and monitoring for symptoms may help to reduce transmission rates. Despite the high level of technology and ongoing research, at the present time there is no highly effective vaccine against avian influenza H5N1 virus that can be manufactured commercially on a large scale for use at low doses.


id: cord-330692-rqwkkfp0
author: He, Daihai
title: Comparing COVID-19 and the 1918–19 influenza pandemics in United Kingdom
date: 2020-06-26
extension: .txt
mime: text/plain
words: 728
sentence: 29
flesch: 46
cache: cache/cord-330692-rqwkkfp0.txt
txt: txt/cord-330692-rqwkkfp0.txt
summary:
  In particular, COVID-19 may have a similar latent period as that of influenza;  Years of Life lost due to pneumonia and influenza between 1911 and 1921 in London, UK SARS-CoV-2 viral load in upper respiratory specimens of infected patients Virological assessment of hospitalized patients with COVID-2019 Superspreading and the effect of individual variation on disease emergence Influenza transmission in households during the 1918 pandemic Clustering and superspreading potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in Hong Kong Mechanistic modelling of the three waves of the 1918 influenza pandemic Prioritization of influenza pandemic vaccination to minimize years of life lost Assessment of Deaths From COVID-19 and From Seasonal Influenza Reconstruction of Transmission Pairs for novel Coronavirus Disease 2019 (COVID-19) in mainland China: Estimation of Super-spreading Events, Serial Interval, and Hazard of Infection The effect of public health measures on the 1918 influenza pandemic in US cities Inferring the causes of the three waves of the 1918 influenza pandemic in England and Wales Acknowledgements DH thanks Jonathan Dushoff, Lewi Stone and David Earn for insightful discussion.


id: cord-286743-z0e5arlm
author: Langer-Gould, Annette
title: Early Identification of COVID-19 Cytokine Storm and Treatment with Anakinra or Tocilizumab
date: 2020-08-06
extension: .txt
mime: text/plain
words: 4303
sentence: 154
flesch: 36
cache: cache/cord-286743-z0e5arlm.txt
txt: txt/cord-286743-z0e5arlm.txt
summary:
  Anakinra, a short-acting IL-1 receptor antagonist is the preferred treatment for severe forms of cytokine storm for patients with underlying conditions other than COVID-19, but its use was not reported for COVID-19 patients in China. In many clinical settings, tocilizumab and, to a lesser extent anakinra, are being used to treat COVID-19 patients with very little information to guide patient selection, dosing or monitoring of treatment response.


id: cord-318808-1cfwj5uq
author: Li, Ying
date: 2020-06-12
extension: .txt
mime: text/plain
words: 1656
sentence: 69
flesch: 45
cache: cache/cord-318808-1cfwj5uq.txt
txt: txt/cord-318808-1cfwj5uq.txt
title:
  Comparison of Hospitalized Patients with pneumonia caused by COVID-19 and influenza A in children under 5 years

summary:
  Two group of COVID-19 patients (n=57) and influenza A patients (n=59) were enrolled. Results The proportions of cough (70.2%), fever (54.4%) and gastrointestinal symptoms (14.1%) in COVID-19 patients were lower than those of influenza A patients (98.3%, P<0.001; 84.7%, P<0.001; and 35.6%, P=0.007; respectively).


id: cord-343789-6tq0kcfd
author: Al-Tawfiq, Jaffar A.
date: 2014-01-06
extension: .txt
mime: text/plain
words: 2633
sentence: 126
flesch: 55
cache: cache/cord-343789-6tq0kcfd.txt
txt: txt/cord-343789-6tq0kcfd.txt
title:
  Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study

summary:
  Taking stock of the first 133 MERS coronavirus cases globally-is the epidemic changing? Middle East respiratory syndrome coronavirus (MERS-CoV)-update Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia A family cluster of Middle East respiratory syndrome coronavirus infections related to a likely unrecognized asymptomatic or mild case Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study KSA MERS-CoV Investigation Team. Hospital outbreak of Middle East respiratory syndrome coronavirus Family cluster of Middle East respiratory syndrome coronavirus infections Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)-possible lessons from a systematic review of SARS-CoV therapy Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak Investigational use of ribavirin in the treatment of severe acute respiratory syndrome Identification of severe acute respiratory syndrome in Canada A cluster of cases of severe acute respiratory syndrome in Hong Kong Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China Effectiveness of antiviral treatment in human influenza A(H5N1) infections: analysis of a global patient registry Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus Inhibition of novel b coronavirus replication by a combination of interferon-a2b and ribavirin Treatment with interferon-a2b and ribavirin improves outcome in MERS-CoVinfected rhesus macaques Product Information: REBETOL (R) oral capsules solution, ribavirin oral capsules solution The authors (JAT, HM, and JD) wish to acknowledge the use of the Saudi Aramco Medical Services Organization (SAMSO) facilities for the data and study, which resulted in this paper.


id: cord-283891-m36un1y2
author: Hu, Bisong
date: 2020-05-17
extension: .txt
mime: text/plain
words: 4664
sentence: 175
flesch: 41
cache: cache/cord-283891-m36un1y2.txt
txt: txt/cord-283891-m36un1y2.txt
title:
  First, second and potential third generation spreads of the COVID-19 epidemic in mainland China: an early exploratory study incorporating location-based service data of mobile devices

summary:
  Conclusions The findings provide important foundations to quantify the effect of human movement on epidemic spread and inform ongoing control strategies. The results indicate the spatiotemporal characteristics of the epidemic spread associated to human movements from epidemic sources and the potential spatiotemporal risks at the early stage of the outbreak.


id: cord-340410-s9haq8y1
author: Fukumoto, Tatsuya
title: Efficacy of a novel SARS-CoV-2 detection kit without RNA extraction and purification
date: 2020-06-26
extension: .txt
mime: text/plain
words: 1073
sentence: 43
flesch: 56
cache: cache/cord-340410-s9haq8y1.txt
txt: txt/cord-340410-s9haq8y1.txt
summary:
  However, it remained to be elucidated whether saliva samples could be applied to the nCoV-DK, since saliva has high RNase (Pandit et al., 2013) . The 2019 Novel Coronavirus Detection Kit (nCoV-DK, Shimadzu Corporation, Kyoto, Japan) eliminates the steps of RNA extraction and purification by using the Ampdirect TM technology (Nishimura et al., 2010) , thus significantly reducing the time required for sample preparation and PCR detection from more than 2 hours to about 1 hour.


id: cord-332348-yi85sfks
author: Liang, Yujie
title: Neurosensory dysfunction: a diagnostic marker of early COVID-19
date: 2020-06-29
extension: .txt
mime: text/plain
words: 2751
sentence: 139
flesch: 52
cache: cache/cord-332348-yi85sfks.txt
txt: txt/cord-332348-yi85sfks.txt
summary:
  However, no difference was noted in viral load between patients with and without neurosensory dysfunction, suggesting that the effect of viral load on the development of neurosensory dysfunction varies. key: cord-332348-yi85sfks authors: Liang, Yujie; Xu, Jiabin; Chu, Mei; Mai, Jianbo; Lai, Niangmei; Tang, Wen; Yang, Tuanjie; Zhang, Sien; Guan, Chenyu; Zhong, Fan; Yang, Liuping; Liao, Guiqing title: Neurosensory dysfunction: a diagnostic marker of early COVID-19 date: 2020-06-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.06.086 sha: doc_id: 332348 cord_uid: yi85sfks Abstract Objectives To detailly described the neurosensory dysfunction, including hyposmia, hypogeusia and tinnitus, in patients with COVID-19.


id: cord-340992-88t1c0zs
author: Nikolai, Lea A
title: Asymptomatic SARS Coronavirus 2 infection: Invisible yet invincible
date: 2020-09-03
extension: .txt
mime: text/plain
words: 3092
sentence: 116
flesch: 33
cache: cache/cord-340992-88t1c0zs.txt
txt: txt/cord-340992-88t1c0zs.txt
summary:
  When assessing public health risks raised by asymptomatic COVID-19 cases it is important to determine whether the infectivity varies between asymptomatic, presymptomatic and symptomatic individuals. The estimated proportion of asymptomatic infections ranges from 18% to 81%.


id: cord-351740-779g8tr1
author: Khaba, Moshawa Calvin
title: COVID-19 in an HIV-infected patient. Lessons learned from an autopsy case
date: 2020-09-25
extension: .txt
mime: text/plain
words: 1830
sentence: 98
flesch: 51
cache: cache/cord-351740-779g8tr1.txt
txt: txt/cord-351740-779g8tr1.txt
summary:
  J o u r n a l P r e -p r o o f Articles Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy : a two-centre descriptive study Clinical Characteristics and Outcomes in People Living With Human Immunodeficiency Virus Hospitalized for Coronavirus Disease Articles Pulmonary and cardiac pathology in African American patients with COVID-19 : an autopsy series from New Orleans Articles Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State : a case series Hematologic parameters in patients with COVID-19 infection Clinical features and outcomes of HIV patients with coronavirus disease 2019 COVID -19 in people living with human immunodeficiency virus : a case series of 33 patients Outcomes Among HIV-Positive Patients Hospitalized With COVID-19 The final cause of death was SARS-CoV-2 (COVID-19) infection in HIV infected patient.


id: cord-330136-o8df8szx
author: Fan, Hua
title: Cardiac injuries in patients with coronavirus disease 2019: Not to be ignored
date: 2020-05-11
extension: .txt
mime: text/plain
words: 2170
sentence: 104
flesch: 49
cache: cache/cord-330136-o8df8szx.txt
txt: txt/cord-330136-o8df8szx.txt
summary:
  Therefore, it is of great clinical significance to explore the clinical features and factors influencing prognosis of COVID-19 patients. This study enrolled COVID-19 patients, including 47 non-survivors and 26 survivors, admitted to the ICU.


id: cord-338576-gh1plurq
author: Regen, Francesca
title: A Simple Approach to Optimum Pool Size for Pooled SARS-CoV-2 Testing
date: 2020-08-28
extension: .txt
mime: text/plain
words: 1203
sentence: 37
flesch: 39
cache: cache/cord-338576-gh1plurq.txt
txt: txt/cord-338576-gh1plurq.txt
summary:
  While the probability Pn of a pool of size ps being negative at target prevalence (p) can be described as = (1 − ) , the probability of a pool being positive (Pp) can be described as This simplifies as The optimum pool size for a given frequency is defined by the local minima of the isolines in figure 1A and can be more precisely determined by the first derivative of equation 1 Results from our analysis clearly demonstrate the relation between target prevalence rates and optimum pool sizes in a two staged pooling strategy. Local minima suggest optimum pool sizes at the respective target prevalence rate (isolines; A).


id: cord-323455-26xi2lqf
author: AlBarrak, Ali
date: 2018-02-21
extension: .txt
mime: text/plain
words: 4240
sentence: 149
flesch: 41
cache: cache/cord-323455-26xi2lqf.txt
txt: txt/cord-323455-26xi2lqf.txt
title:
  Proportion of adult community-acquired pneumonia cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016

summary:
  A proportion of CAP cases among Hajj pilgrims were attributable to S. pneumoniae, a pathogen for which vaccines are available. Patients were enrolled from all general hospitals (excluding specialty hospitals such as obstetrics and gynecology hospitals and pediatric hospitals) designated to treat Hajj pilgrims.


id: cord-339576-0d6sa9pe
author: Guallar, María Pilar
title: Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
date: 2020-06-14
extension: .txt
mime: text/plain
words: 1381
sentence: 55
flesch: 48
cache: cache/cord-339576-0d6sa9pe.txt
txt: txt/cord-339576-0d6sa9pe.txt
summary:
  For COVID-19, high viral loads either in saliva, respiratory secretions or blood have been associated with more severe illness [3, 4] . A relationship between the infecting dose and the risk of disease severity has been demonstrated for several viral infections, including influenza and SARS [1, 2] .


id: cord-319814-tyqb473m
author: Zhang, Dingmei
date: 2014-06-11
extension: .txt
mime: text/plain
words: 3483
sentence: 150
flesch: 44
cache: cache/cord-319814-tyqb473m.txt
txt: txt/cord-319814-tyqb473m.txt
title:
  Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in southern China

summary:
  Implications for design of vaccine trials Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis Epidemiology of respiratory viral infections in two long-term refugee camps in Kenya Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing Parainfluenza virus infection of young children: estimates of the populationbased burden of hospitalization Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays Epidemiology of respiratory virus infections among infants and young children admitted to hospital in Oman Novel human bocavirus in children with acute respiratory tract infection Epidemiology of human metapneumovirus Respiratory syncytial virus and parainfluenza virus Mortality attributable to 9 common infections: significant effect of influenza A, respiratory syncytial virus, influenza B, norovirus, and parainfluenza in elderly persons Characterization of a novel coronavirus associated with severe acute respiratory syndrome The 1918 'Spanish' flu: pearls from swine Human respiratory syncytial virus in children with acute respiratory tract infections in China Genetic variability of respiratory syncytial viruses (RSV) prevalent in southwestern China from 2006 to 2009: emergence of subgroup B and A RSV as dominant strains Molecular monitoring of causative viruses in child acute respiratory infection in endemo-epidemic situations in Shanghai Simultaneous detection of influenza A, B, and C viruses, respiratory syncytial virus, and adenoviruses in clinical samples by multiplex reverse transcription nested-PCR assay Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia Detection of adenoviruses in stools from healthy persons and patients with diarrhea by two-step polymerase chain reaction Bocavirus infection in hospitalized children WHO estimates of the causes of death in children Seasonal influenza vaccines The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines Current status of vaccines for parainfluenza virus infections Parainfluenza viruses Parainfluenza virus type 3: seasonality and risk of infection and reinfection in young children Molecular characterization and phylogenetic analysis of human parainfluenza virus type 3 isolated from Saudi Arabia Cloning of a human parvovirus by molecular screening of respiratory tract samples Human bocavirus infection in young children in the United States: molecular epidemiological profile and clinical characteristics of a newly emerging respiratory virus Human bocavirus: a novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in Thailand Human bocavirus in Italian patients with respiratory diseases Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections Human bocavirus infection in children with acute gastroenteritis in Japan and Thailand Human bocavirus 1 and 3 infection in children with acute gastroenteritis in Brazil Respiratory syncytial virus infection in tropical and developing countries Evaluation of viral co-infections in hospitalized and non-hospitalized children with respiratory infections using microarrays Multipathogen infections in hospitalized children with acute respiratory infections Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children The detection of the specific viral causes of infection provides a useful starting point for an understanding of illness attributable to respiratory infection, and might also provide data relevant to the development of prevention strategies. of risk factors is critical to the successful implementation of a prevention and control program.


id: cord-317399-693q80xo
author: Al Wahaibi, Adil
date: 2020-08-20
extension: .txt
mime: text/plain
words: 3650
sentence: 146
flesch: 50
cache: cache/cord-317399-693q80xo.txt
txt: txt/cord-317399-693q80xo.txt
title:
  COVID-19 epidemic monitoring after non-pharmaceutical interventions: the use of time-varying reproduction number in a country with a large migrant population

summary:
  With the increasing numbers of COVID-19 cases in Oman, our study showed the feasibility of using the time-varying Rt to assess and explain transmissibility dynamics and epidemic progression. Allowing 50% of governmental employees to return to work (May 31st) Opening of Muscat Governorate (May 29th) Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study Effect of non-pharmaceutical interventions for containing the COVID-19 outbreak in China.


id: cord-355480-mx9dbm73
author: Bajunirwe, Francis
title: Long distance truck drivers and the increasing risk of COVID-19 spread in Uganda
date: 2020-06-29
extension: .txt
mime: text/plain
words: 1706
sentence: 67
flesch: 56
cache: cache/cord-355480-mx9dbm73.txt
txt: txt/cord-355480-mx9dbm73.txt
summary:
  In this paper, we track the reports of new COVID-19 cases reported by the MoH and trace the emerging patterns of the new cases reported and identify the categories of persons at high risk for COVID-19 in Uganda. We reviewed MoH reports and press releases for new COVID-19 cases detected in Uganda as they were made public on a regular basis.


id: cord-354780-yzyixucr
author: Lin, Chih-Yen
title: Importation of SARS-CoV-2 infection leads to major COVID-19 epidemic in Taiwan
date: 2020-06-13
extension: .txt
mime: text/plain
words: 1762
sentence: 81
flesch: 53
cache: cache/cord-354780-yzyixucr.txt
txt: txt/cord-354780-yzyixucr.txt
summary:
  To reduce the effects of COVID-19 importation to Taiwan, Taiwan CDC has implemented relevant prevention strategies. Before the mid of March, the incidence of COVID-19 importation was 0.58 average per day.


id: cord-305763-160heazx
author: Lai, Chih-Cheng
title: Population-based seroprevalence surveys of anti-SARS-CoV-2 antibody: An up-to-date review
date: 2020-10-09
extension: .txt
mime: text/plain
words: 4262
sentence: 110
flesch: 38
cache: cache/cord-305763-160heazx.txt
txt: txt/cord-305763-160heazx.txt
summary:
  In Denmark, a total of 20,640 blood donations were given by 17-69-year-old donors from April 6 to May 3, 2020, which were then subjected to a plasma or whole blood lateral flow test according to the manufacturer's recommendations (IgM/IgG Antibody to SARS-CoV-2 lateral flow test; Livzon Diagnostics Inc., Zhuhai, Guangdong, China) (Erikstrup et al et al., 2020) . The overall unadjusted seroprevalence was 2.0% (95% CI, 1.8-2.2), and after adjusting for assay sensitivity and specificity (including their CI), the overall seroprevalence was 1.9% (95% CI, 0.8-2.3) (Erikstrup et al et al., 2020) .


id: cord-330819-vfagxsdz
author: Althouse, Benjamin M
date: 2018-08-14
extension: .txt
mime: text/plain
words: 4665
sentence: 148
flesch: 32
cache: cache/cord-330819-vfagxsdz.txt
txt: txt/cord-330819-vfagxsdz.txt
title:
  Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam

summary:
  Seminars in respiratory and critical care medicine Wavelet analysis of ecological time series Epidemiology of respiratory syncytial virus infection among paediatric patients in hong kong: seasonality and disease impact Seasonal variation in respiratory syncytial virus chest infection in the tropics Climate cycles and forecasts of cutaneous leishmaniasis, a nonstationary vector-borne disease Seasonal trends of viral respiratory tract infections in the tropics Modified recommendations for use of palivizumab for prevention of respiratory syncytial virus infections Global seasonality of rotavirus infections Viral etiologies of acute respiratory infections among hospitalized vietnamese children in ho chi minh city Seasonal patterns of invasive pneumococcal disease Dynamical resonance can account for seasonality of influenza epidemics Measles in england and wales-i: an analysis of factors underlying seasonal patterns Early indication for a reduced burden of radiologically confirmed pneumonia in children following the introduction of routine vaccination against haemophilus influenzae type b in nha trang, vietnam Seasonal trends of human parainfluenza viral infections: United states Application of the cross wavelet transform and wavelet coherence to geophysical time series Respiratory syncytial virus and parainfluenza virus Viral etiology and epidemiology of acute respiratory infections in children in nairobi, kenya Complex dynamics of synergistic coinfections on realistically clustered networks Pathogen mutation modeled by competition between site and bond percolation Subgrouping of respiratory syncytial virus strains from australia and papua new guinea by biological and antigenic characteristics Epidemiology of respiratory syncytial virus infection among paediatric inpatients in northern taiwan Epidemiology and seasonality of respiratory viral infections in hospitalized children in kuala lumpur, malaysia: a retrospective study of 27 years Considerations of strategies to provide influenza vaccine year round Extending the cure: policy responses to the growing threat of antibiotic resistance Antibiotic resistance-the need for global solutions Access to effective antimicrobials: a worldwide challenge Circulation of influenza b lineages in northern viet nam Incubation periods of acute respiratory viral infections: a systematic review A simultaneous outbreak of respiratory syncytial virus and parainfluenza virus type 3 in a newborn nursery Impact of birth rate, seasonality and transmission rate on minimum levels of coverage needed for rubella vaccination Aerosol stability of three acute respiratory disease viruses Global summary of the day (GSOD) global summary of the day (GSOD Epidemiology of influenza in hanoi, vietnam Climatic, temporal, and geographic characteristics of respiratory syncytial virus disease in a tropical island population Environmental factors affecting the transmission of respiratory viruses Respiratory syncytial virus infection and prevalence of subgroups a and b in hawaii Influenza seasonality and vaccination timing in tropical and subtropical areas of southern and south-eastern asia Epidemiology and seasonality of respiratory tract virus infections in the tropics Viral etiology of acute respiratory infections among children in porto alegre, rs, brazil Timing of antimicrobial use influences the evolution of antimicrobial resistance during disease epidemics Correlations between climate factors and incidence-a contributor to rsv seasonality Seasonality of absolute humidity explains seasonality of influenza-like illness in vietnam Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data Antibiotic use and resistance in emerging economies: a situation analysis for viet nam Global burden of childhood pneumonia and diarrhoea Pneumonia: the leading killer of children The clinical spectrum of respiratory syncytial virus disease in the gambia Viral pathogens associated with acute respiratory infections in central vietnamese children Population based cohort study for pediatric infectious diseases research in vietnam key: cord-330819-vfagxsdz authors: Althouse, Benjamin M; Flasche, Stefan; Minh, Le Nhat; Thiem, Vu Dinh; Hashizume, Masahiro; Ariyoshi, Koya; Anh, Dang Duc; Rodgers, Gail L.; Klugman, Keith P.; Hu, Hao; Yoshida, Lay-Myint title: Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam date: 2018-08-14 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2018.08.001 sha: doc_id: 330819 cord_uid: vfagxsdz BACKGROUND: Acute respiratory infections (ARIs) are the most common causes of death in children under 5 years of age.


id: cord-346461-eqyte6ko
author: Scialpi, Michele
title: Pneumonia misinterpretation in COVID-19: revisitation and update
date: 2020-08-28
extension: .txt
mime: text/plain
words: 507
sentence: 17
flesch: 23
cache: cache/cord-346461-eqyte6ko.txt
txt: txt/cord-346461-eqyte6ko.txt
summary:
  The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Emerging 2019 novel coronavirus (2019-nCoV) pneumonia Chest CT features of COVID-19 in Rome Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Time course of lung changes on chest CT during recovery from The progression of computed tomographic (CT) images in patients with coronavirus disease (COVID-19) pneumonia: the CT progression of COVID-19 pneumonia Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The experience of clinical immunologists from China Comorbidities and multi-organ injuries in the treatment of COVID Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study Acute pulmonary embolism: Lung histopatologic fetures are mainly related to ADA and/or associated with PE and a conseguent respiratory failure causing death in COVID-19 patients.


id: cord-284652-7npya3yx
author: Shim, Eunha
date: 2020-10-08
extension: .txt
mime: text/plain
words: 3738
sentence: 122
flesch: 46
cache: cache/cord-284652-7npya3yx.txt
txt: txt/cord-284652-7npya3yx.txt
title:
  Spatial variability in reproduction number and doubling time across two waves of the COVID-19 pandemic in South Korea, February to July 2020

summary:
  South China Morning Post2020 Surge in South Korea virus cases linked to church 'super-spreader'. As the number of COVID-19 cases continued to increase, Korean public health authorities set the alert to the highest level (Level 4) on 23 February and mandated the population to report any symptoms related to for further screening and testing.


id: cord-324231-nik7xizn
author: Aitsi-Selmi, Amina
date: 2016-04-07
extension: .txt
mime: text/plain
words: 2883
sentence: 83
flesch: 27
cache: cache/cord-324231-nik7xizn.txt
txt: txt/cord-324231-nik7xizn.txt
title:
  Reducing risks to health and wellbeing at mass gatherings: the role of the Sendai Framework for Disaster Risk Reduction

summary:
  There is global agreement that disasters are not natural events and that disaster risk arises as the result of the interaction between hazards (natural hazards such as earthquakes or human-made hazards such as anthropogenic climate change) and predisposing vulnerabilities and exposures. The Sendai Framework outcome for the next 15 years is to achieve ''The substantial reduction of disaster risk and losses in lives, livelihoods and health and in the economic, physical, social, cultural and environmental assets of persons, businesses, communities and countries''.


id: cord-355343-dtdsd8j2
author: Buonsenso, Danilo
title: Social consequences of COVID-19 in a low resource setting in Sierra Leone, West Africa
date: 2020-06-01
extension: .txt
mime: text/plain
words: 1272
sentence: 37
flesch: 45
cache: cache/cord-355343-dtdsd8j2.txt
txt: txt/cord-355343-dtdsd8j2.txt
summary:
  We drafted a survey in order to urgently address the social impact of COVID-19 lockdown on the rural village of Bureh Town, Sierra Leone, West Africa (figure 1) and quickly implement corrective measures. key: cord-355343-dtdsd8j2 authors: Buonsenso, Danilo; Cinicola, Bianca; Raffaelli, Francesca; Sollena, Pietro; Iodice, Francesco title: Social consequences of COVID-19 in a low resource setting in Sierra Leone, West Africa date: 2020-06-01 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.05.104 sha: doc_id: 355343 cord_uid: dtdsd8j2 Economical and psychological consequences of the lockdown in low-resource setting in rural Africa are unknown.


id: cord-347349-caz5fwl1
author: Yu, Xinhua
date: 2020-07-02
extension: .txt
mime: text/plain
words: 3803
sentence: 140
flesch: 49
cache: cache/cord-347349-caz5fwl1.txt
txt: txt/cord-347349-caz5fwl1.txt
title:
  Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea

summary:
  In summary, in South Korea, and likely in other countries, COVID-19 epidemic processes had distinctive dynamic patterns among age and gender groups. key: cord-347349-caz5fwl1 authors: Yu, Xinhua; Duan, Jiasong; Jiang, Yu; Zhang, Hongmei title: Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea date: 2020-07-02 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.06.101 sha: doc_id: 347349 cord_uid: caz5fwl1 OBJECTIVES:


id: cord-321412-6g3obmzc
author: Khamis, Faryal
title: Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection
date: 2020-06-23
extension: .txt
mime: text/plain
words: 3143
sentence: 112
flesch: 45
cache: cache/cord-321412-6g3obmzc.txt
txt: txt/cord-321412-6g3obmzc.txt
summary:
  The use of TPE in severe COVID-19 patients has been associated with improved outcomes, however, randomized controlled clinical trials are warranted to draw final conclusive findings. The declare no conflict of interest J o u r n a l P r e -p r o o f J o u r n a l P r e -p r o o f COVID-19 pandemic by country and territory A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 Available at Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease Effective treatment of severe COVID-19 patients with tocilizumab Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis Use of therapeutic plasma exchange as a rescue therapy in 2009 pH1N1 influenza A--an associated respiratory failure and hemodynamic shock The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single center retrospective review Successful treatment of plasma exchange followed by intravenous immunogloblin in a critically ill patient with 2019 novel coronavirus infection Efficacy of therapeutic plasma exchange in severe COVID-19 patients Acute respiratory distress syndrome: the Berlin Definition Human infection with novel corona virus (COVID-19)-7.


id: cord-341775-mucatzaa
author: Shafi, Shuja
date: 2016-06-22
extension: .txt
mime: text/plain
words: 2254
sentence: 81
flesch: 41
cache: cache/cord-341775-mucatzaa.txt
txt: txt/cord-341775-mucatzaa.txt
title:
  The annual Hajj pilgrimage—minimizing the risk of ill health in pilgrims from Europe and opportunity for driving the best prevention and health promotion guidelines

summary:
  However, there is conflicting evidence about the efficacy of influenza vaccine in protecting Hajj pilgrims. [24] [25] [26] Meningococcal vaccine is a prerequisite for all pilgrims; Hajj visas cannot be issued without proof of meningococcal vaccination.


id: cord-323332-vu2cre8k
author: Luo, Yang
title: Factors impacting compliance with standard precautions in nursing, China
date: 2010-11-10
extension: .txt
mime: text/plain
words: 3985
sentence: 166
flesch: 43
cache: cache/cord-323332-vu2cre8k.txt
txt: txt/cord-323332-vu2cre8k.txt
summary:
  These consisted of four parts and included (1) standard questions to gather participant information, (2) questions pertaining to standard precautions knowledge, (3) questions on compliance with standard precautions, and (4) a general self-efficacy scale. Pearson's correlation was used in the analysis of standard precautions knowledge, compliance with standard precautions, and general self-efficacy.


id: cord-347499-7q47jh14
author: Burrel, Sonia
date: 2020-10-25
extension: .txt
mime: text/plain
words: 1356
sentence: 41
flesch: 36
cache: cache/cord-347499-7q47jh14.txt
txt: txt/cord-347499-7q47jh14.txt
title:
  Co-infection of SARS-CoV-2 with other respiratory viruses and performance of lower respiratory tract samples for the diagnosis of COVID-19

summary:
  We performed a study during the early outbreak period of coronavirus disease 2019 (COVID-19) and the seasonal epidemics of other respiratory viral infections in order to describe the extent of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with other respiratory viruses. In conclusion, the detection of other respiratory viruses in patients during epidemic period cannot rule out SARS-CoV-2 co-infection, and LRT samples increases the accuracy of diagnosis of viral respiratory infections, including COVID-19.


id: cord-324295-9c1zxjng
author: Bonilla-Aldana, D. Katterine
date: 2020-08-20
extension: .txt
mime: text/plain
words: 3771
sentence: 134
flesch: 40
cache: cache/cord-324295-9c1zxjng.txt
txt: txt/cord-324295-9c1zxjng.txt
title:
  Bats in Ecosystems and their Wide Spectrum of Viral Infectious Threats: SARS-CoV-2 and other emerging viruses

summary:
  A study detected a high seroprevalence of antibodies against Marburg virus in fruit bats in South Africa, with a 19.1% seroconversion rate in recaptured bats 24 ; Another study detected MARV genome in bats captured in Zambia 25 ; and a posterior serosurvey identified filovirus-specific immunoglobulin G antibodies in 71 out of 748 serum samples collected from migratory fruit bats 26 . Multiple studies point at bats of the genus Myotis as the main reservoir for Ebola virus given that these bats carry a copy of viral gene VP35 (Table 3) Studies in Africa analyzed 4,022 blood samples from bats, detecting antibodies against Ebola virus in one genus of insectivorous bats and six species of fruit bats 29 .


id: cord-345275-h0hvaxgx
author: Sun, Mengyao
date: 2020-07-04
extension: .txt
mime: text/plain
words: 5313
sentence: 239
flesch: 53
cache: cache/cord-345275-h0hvaxgx.txt
txt: txt/cord-345275-h0hvaxgx.txt
title:
  Potential effective treatment for COVID-19: systematic review and meta-analysis of the severe infectious disease with convalescent plasma therapy

summary:
  CP therapy is a form of passive immunisation in which antibody-rich blood is collected from recovered patients and then processed to transfuse into other patients. CP therapy has been effective for treating diphtheria and tetanus since the late 19th century, but the earliest complete record dates back to the outbreak of the Spanish influenza pandemic in 1918.


id: cord-349418-98sgr5iv
author: Bo, Yacong
date: 2020-10-29
extension: .txt
mime: text/plain
words: 4194
sentence: 140
flesch: 43
cache: cache/cord-349418-98sgr5iv.txt
txt: txt/cord-349418-98sgr5iv.txt
title:
  Effectiveness of non-pharmaceutical interventions on COVID-19 transmission in 190 countries from 23 January to 13 April 2020

summary:
  Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2 The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis A new framework and software to estimate time-varying reproduction numbers during epidemics Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study Effects of nonpharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study An interactive web-based dashboard to track COVID-19 in real time Serial Interval of COVID-19 among Publicly Reported Confirmed Cases To mask or not to mask: If any NPI of a type was deemed officially announced as being in force at a site on any day of the study period, that NPI type was treated as 'on' for that site on that day in our data J o u r n a l P r e -p r o o f analysis.


id: cord-349645-6o8773c5
author: Li, He
title: Air Pollution and temperature are associated with increased COVID-19 incidence: a time series study
date: 2020-06-02
extension: .txt
mime: text/plain
words: 3019
sentence: 120
flesch: 42
cache: cache/cord-349645-6o8773c5.txt
txt: txt/cord-349645-6o8773c5.txt
summary:
  As the SARS-CoV-2 has a median incubation period of 4 days in human (Guan et al., 2020) , all independent variables were used to fit daily COVID-19 incidence from 4 days later. Interestingly, all ambient air pollutants showed positive association with daily COVID-19 incidence.


id: cord-356074-kw8c2fgk
author: Oboh, Mary Aigbiremo
date: 2020-08-13
extension: .txt
mime: text/plain
words: 1656
sentence: 62
flesch: 31
cache: cache/cord-356074-kw8c2fgk.txt
txt: txt/cord-356074-kw8c2fgk.txt
title:
  Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks

summary:
  key: cord-356074-kw8c2fgk authors: Oboh, Mary Aigbiremo; Omoleke, Semeeh Akinwale; Ajibola, Olumide; Manneh, Jarra; Kanteh, Abdoulie; Sesay, Abdul-Karim; Amambua-Ngwa, Alfred title: Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks date: 2020-08-13 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.08.027 sha: doc_id: 356074 cord_uid: kw8c2fgk BACKGROUND: Union rolls out Partnership to Accelerate COVID-19 Testing Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases Strengthening Africa ' s ability to ' decode ' the coronavirus The 100,000 Genomes Project Protocol v3 Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study Nanopore sequencing as a rapidly deployable Ebola outbreak tool Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Quagmire of epidemic disease outbreaks reporting in Nigeria Real-time, portable genome sequencing for Ebola surveillance The cost and cost trajectory of whole-genome analysis guiding treatment of patients with advanced cancers WHO ramps up preparedness for novel coronavirus in the African region WHO.


id: cord-347907-0nrejsgr
author: Alqahtani, Amani S.
date: 2016-02-10
extension: .txt
mime: text/plain
words: 4274
sentence: 182
flesch: 49
cache: cache/cord-347907-0nrejsgr.txt
txt: txt/cord-347907-0nrejsgr.txt
title:
  Exploring barriers to and facilitators of preventive measures against infectious diseases among Australian Hajj pilgrims: cross-sectional studies before and after Hajj

summary:
  Parliament of Australia Health Regulations for travelers to Saudi Arabia for Umrah and pilgrimage (Hajj) Australian Government Department of Foreign Affairs and Trade Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers Knowledge, attitude and practice (KAP) survey concerning antimicrobial use among Australian Hajj pilgrims The inevitable Hajj cough: surveillance data in French pilgrims Changes in the prevalence of influenza-like illness and influenza vaccine uptake among Hajj pilgrims: a 10-year retrospective analysis of data Pneumococcal vaccine uptake among Australian Hajj pilgrims in 2011-13 Prevention of pneumococcal infections during mass gathering Etiology of severe community-acquired pneumonia during the 2013 Hajj-part of the MERS-CoV surveillance program Pneumococcal infections at Hajj: current knowledge gaps Australian Hajj pilgrims' knowledge about MERS-CoV and other respiratory infections French Hajj pilgrims' experience with pneumococcal infection and vaccination: a knowledge, attitudes and practice (KAP) evaluation Health conditions for travellers to Saudi Arabia for the Umra and pilgrimage to Mecca (Hajj)-2014 Pilgrims from Marseille, France, to Mecca: demographics and vaccination status Pattern of diseases and preventive measures among domestic Hajjis from Riyadh, 1431 H Hazards of hepatitis at the Hajj Global perspectives for prevention of infectious diseases associated with mass gatherings Epidemiological pattern of diseases and risk behaviors of pilgrims attending Mina hospitals, Hajj 1427 h (2007 g) Pre-Hajj health-related advice Determinants of tetanus, diphtheria and poliomyelitis vaccinations among Hajj pilgrims, Marseille, France Prevalence of MERS-CoV nasal carriage and compliance with the Saudi Health recommendations among pilgrims attending the 2013 Hajj Behavioral risk factors for diseases during Hajj 1422 H Detection of respiratory viruses among pilgrims in Saudi Arabia during the time of a declared influenza A (H1N1) pandemic Predictors for the uptake of recommended vaccinations in Mecca travelers who visited the Public Health Service Amsterdam for mandatory meningitis vaccination Predictors of protective behaviors among American travelers to the 2009 Hajj Respiratory viruses and bacteria among pilgrims during the 2013 Hajj The use of facemasks to prevent respiratory infection: a literature review in the context of the Health Belief Model Air quality in Mecca and surrounding holy places in Saudi Arabia during Hajj: initial survey Incidence of Hajj-related acute respiratory infection among Hajjis from Riyadh Hajj-associated acute respiratory infection among Hajjis from Riyadh Sources of health education for international Arab pilgrims and the effect of this education on their practices towards health hazards in Hajj Time for patient leaflets on the Hajj There is currently no formal guidance from the Saudi MoH on the use of pneumococcal vaccine for Hajj pilgrims, which may partly explain this apparent lack of awareness (Table 1) .


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