key: cord-282177-8l7zukg4
authors: Lin, Yi-Chun; Cheng, Chien-Yu; Cheng-Pin, Chen; Cheng, Shu-Hsing; Chang, Sui-Yuan; Hsueh, Po-Ren
title: A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
date: 2020-05-26
journal: Int J Infect Dis
DOI: 10.1016/j.ijid.2020.05.070
sha: 
doc_id: 282177
cord_uid: 8l7zukg4

ABSTRACT We report a patient who had travelled to Japan presented mild respiratory symptom during the COVID-19 infection outbreak period. There was transient existence of SARS-CoV-2 RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. Anti-SARS-CoV-2 antibody response in the acute and convalescent sera were absent. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus.

Early diagnosis of COVID-19 is essential for containing and mitigating SARS- 

A 30-year-old man, an engineer, presented to our hospital on February 27, 2020, with a mild cough since February 24, 2020 (day 1 of illness 

Informed consent was obtained from the patient for publication of this case report.

No specific funding was received for this work.

The authors declare no competing interests

☒ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. 

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