Table 1. Chemotherapy regimens on Turkish Pediatric Oncology Group Neuroblastoma 2003.1

	Chemotherapy
	Drugs
	Schedule

	Induction cycles
A3 – 1 cycle
15-19 July 2019
	
Vincristine
	
1.5 mg/m2/day, D 1 and 5, 
IV push

	
	Ifosfamide
	1.8 g/m2/day,
D 1-5, IV continue infusion

	
	Dacarbazine
	250 mg/m2/day,
D 1-5, IV 30 min

	
	Adriamycin
	20 mg/m2/day,
D 1-3, IV over 4 h

	A5 – 1 cycle
15-19 August 2019
	Cisplatin
	30 mg/m2/day,
D 1-5, IV continue infusion

	
	Cyclophosphamide
	300 mg/m2/day,
D 1-5, IV over 1 h

	
	Etoposide
	150 mg/m2/day,
D 4 and 5, IV 1 h


























Figure 1. (A-F): Coronal and axial views of patients PET in 2014 (A and B); restaging PET showing progressive disease three years later (C). Clinical views after the first radiotherapy, revealing a left-sided neck mass sized 12 cm x 10 cm x 10 cm (D), after two cycles of temozolomide, sized 10 cm x 8 cm x 8cm (E), and after debulking surgery (F).









Figure 2 (A-F). Hematoxylin and eosin (H&E) staining from tissue biopsy (A)100x, (B)200x, and (C)400x, showing clusters and packets of small neoplastic cells forming Homer-Wright rosettes, with fairly dispersed chromatin, inconspicuous nucleoli and indistinct cytoplasm. CD56 (D), chromogranin (E), and synaptophysin (F) IHC stains are positive in this tissue.