28 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 DOI 10.11603/ijmmr.2413-6077.2021.1.12258 RADIATION EXPOSURE IN ACCESSORY PATHWAY ABLATION PROCEDURES IN CARDIAC ELECTROPHYSIOLOGY: A RETROSPECTIVE ANALYSIS *M. Ali1,2, B. Banavalikar1, M.K. Ghadei1, A. Kottayan1, D. Padmanabhan1, J. Shenthar1 1 – DEPARTMENT OF CARDIAC ELECTROPHYSIOLOGY, SRI JAYADEVA INSTITUTE OF CARDIOVASCULAR SCIENCES AND RESEARCH, BANGALORE, INDIA 2 – DEPARTMENT OF CARDIOLOGY, SHER-I-KASHMIR INSTITUTE OF MEDICAL SCIENCES, SRINAGAR, KASHMIR, INDIA Background. Radiofrequency catheter ablation (CA) has been the treatment of choice in patients with accessory pathway (AP)-mediated tachycardias. Most of these procedures are done under fluoroscopic guidance, leading to significant radiation exposure to the patient and the laboratory personnel. In this analysis, we have looked at the amount of radiation exposure in AP CA procedures performed without the support of a three- dimensional electroanatomic mapping system. We have analyzed changes in exposure indices over the study period and the impact of change in fluoroscopy frame rate (FFR). Objectives. The objectives of this study are to quantify radiation exposure in accessory pathway ablation procedures; to analyze the radiation exposure trend over time; and to evaluate the effect of fluoroscopy frame rate reduction on the radiation exposure indices in these procedures. Methods. All the AP ablation procedures performed at our institute from January 2016 to December 2019 were retrospectively analyzed. The collected data were age, sex, location of APs based on successful site of ablation on fluoroscopy, procedure time, fluoroscopy time, and dose-area product (DAP). Effective dose (ED) was estimated from DAP. The data of procedures performed before January 2018 (“pre” group) were compared with those of the procedures performed after that date (“post” group). Pre-group procedures were performed at an FFR of 7.5 frames per second (fps), and post-group procedures – at an FFR of 3.75 fps. Results. The total number of procedures included in the analysis was 635. The mean age of the patients was 39±14 years, and 401 of them (63%) were males. The most common location of the APs was left lateral (38%). Procedure time and radiation indices showed a significant decrease over the study period (p < 0.001). Post group procedures had significantly shorter procedure time and lower radiation exposure than pre group procedures. Conclusions. A decrease in the FFR was associated with a significant reduction in radiation exposure in AP ablation procedures KEYWORDS: accessory pathway; catheter ablation; dose-area product; fluoroscopy time; radiation exposure. Introduction International Journal of Medicine and Medical Research 2021, Volume 7, Issue 1, p. 28-34 copyright © 2021, TNMU, All Rights Reserved *Corresponding author: Dr. Muzaffar Ali, Department of Car- diology, SKIMS, Srinagar, Kashmir, India. Email: dralimuzaf- far@gmail.com The ablation of accessory pathways (AP) using radiofrequency energy was first intro- duced by Borggrefe and colleagues in 1987 when they ablated a right-sided accessory pathway for the first time in humans using radiofrequency energy [1]. Since then, radio- frequency ablation has been the treatment of choice in patients with accessory pathway- mediated tachycardias [2,3]. Although radio- frequency ablation for AP-mediated tachy- cardias is a highly efficacious and safe treatment option, some of the adverse effects of this procedure are not because of the procedure itself but because of the ionizing radiation used to visualize the catheters during the procedure. Ionizing radiation exposure affects the patient and the laboratory personnel because of the fluoroscopic imaging used during cardiac electrophysiology (EP) procedures. The ionizing radiation exposure can cause long-term hazardous effects, including malig- nancy, cataract formation, thyroid dysfunction, dermatitis, germline mutations, etc. This is due to double-strand breaks induced in the DNA backbone brought about by the free radicals M. Ali et al. 29 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 generated due to the exposure of ionizing radiations [4]. The hazard of radiation exposure increases with the higher radiation dose, which in turn increases with the longer duration of EP pro- cedure for the patient and increase in the number of EP procedures for the laboratory staff. Thus, it is essential to evaluate the benefit of the intended EP procedure over the risk of expected exposure to ionizing radiation and minimize the radiation exposure levels to mini- mum achievable levels for both the patients and the laboratory staff to have an overall beneficial outcome of the EP procedure [4]. One way to decrease radiation exposure in cardiac electrophysiology procedures is to use a lower fluoroscopy frame rate. We have pre- viously reported of the impact of fluoroscopy frame rate reduction in complex catheter ablation procedures performed under a three- dimensional electroanatomic mapping system [5]. In this study, we analyzed radiation expo- sure indices in our laboratory’s AP ablation procedures. We have also analyzed the impact of fluoroscopy frame rate reduction on radiation exposure indices during these procedures. The objectives of this study are: to quantify radiation exposure in accessory pathway ab- lation procedures; to analyze the radiation exposure trend over time; and to evaluate the effect of fluoroscopy frame rate reduction on the radiation exposure indices in these pro- cedures. Methods A retrospective analysis of accessory path- way ablation procedures carried out in a tertiary care referral institute in Southern India was performed. The data were collected from January 2016 to December 2019. The data available were age, sex, location of successful ablation, fluoroscopy time, and dose area product (DAP). Procedures without such data were exclu_ ded. Patients with multiple accessory pathways were also excluded from the analysis. The procedure time for catheter ablation procedures was defined as the time from the administration of a local anesthetic agent to removing ca- theters from the patient’s body. Our institute has an ongoing cardiac electrophysiology fellowship program, and the fellows assist in all the catheter ablation procedures performed in our laboratory. Four physicians performed the catheter ablation procedures with an experience of 21, 11, 6, and 4 years in interventional electrophysiology. All the catheter ablation procedures were performed without three- dimensional electroanatomic mapping. The institute has an active EP fellowship program running since 2009, and the fellows assist in all the procedures performed in the laboratory. The laboratory is equipped with the Philips Allura Xper FD 10 system (Philips Healthcare, the Netherlands), and all the procedures were performed using the same system. The fluoroscopy frame rate used in the laboratory was 7.5 fps before February 2018. From the beginning of February 2018, fluo- roscopy at 3.75 fps have been used. The location of the accessory pathways was determined by the location of successful ablation in the left anterior oblique (LAO) projection, as shown in Figure 1. The Effective Dose (ED, mSv) was estimated from DAP provided by the X-ray system by multiplying DAP with the following conversion factors depending on the age of the patient: 5-10 years of age: 1.0; 10-15 years of age: 0.6; 15-20 years of age: 0.4; adult females: 0.28 and adult males: 0.2. Lifetime attributable risk (LAR) of cancer incidence and mortality was derived from the ED by multiplying it with 0.0001/mSv (the standardized BEIR VII conversion factor) [5]. The data were summarized using standard descriptive statistics and presented as the arithmetic means with standard deviation (SD) or median with interquartile range, as appro- priate. Nonparametric statistical tests like the Kruskal-Wallis test and the Mann-Whitney U test were used to analyze the procedure time and radiation exposure parameters over the study period and the effect of fluoroscopy fra- Fig. 1. Location of accessory pathways as seen on a left ante- rior oblique (LAO) projection. HB: His Bundle; LAL: left anterolateral; LL: left lateral; LPL: left posterolateral; LP: left posterior; LPS: left posteroseptal; RPS: right posteroseptal; RP: right posterior; RPL: right posterolat- eral; RL: right lateral; RAL: right anterolateral; RA: right ante- rior; RAS/PH: right anteroseptal/para-Hisian; MS: midseptal. M. Ali et al. 30 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 me rate over various parameters, respectively. The level of significance was fixed at p<0.05. Institutional ethical committee approval was not applied for this retrospective analysis. Informed consent was obtained from all pa- tients before the procedures, which included the clause that their data could be used for scientific purposes in the future. Statistical Package for the Social Sciences (SPSS), version 20, was used to perform sta- tistical analysis. Results Six hundred and thirty-five pathway ablation procedures were included in the analysis. The mean age of the patients was 39±14 years. The mean age of male patients (n=401; 63% of the total) was 39±13 years, and female patients (n=234; 37% of the total) were 40±14 years. The location of the accessory pathways and the associated procedure time and radiation indices are presented in Table 1. The number of the pathways ablated from the left side was 372 (58.6%), and that from the right were 263 (41.4%). The most common location of the ablated pathways was left lateral, which was 38.4 % of all the pathways, and the second most common location was right posteroseptal, which was 27.2% of all the pathways. The least common location of accessory pathways was mid septal (0.3%) followed by right anterolateral (0.5%) and right anterior (0.5%) locations. Trends in various indices over the study period are shown in Table 2. 15% (96) of all the procedures were performed in 2016. In the years 2017, 2018, and 2019 the proportion of the procedures performed was 23% (149), 31% (196), and 31% (194), respectively. Trends in the indices before (pre group) and after (post group) the change in fluoroscopy frame rate are shown in Table 3. 41% of the procedures (n=260) were performed under fluoroscopy frame rate of 7.5 fps, and 59% of the procedures (n=375) were performed under fluoroscopy frame rate of 3.75 fps. Discussion Table 1. Procedure time and radiation indices based on the successful location of ablation on fluoroscopy in left anterior oblique projection Pathways No. (%) ProcedureTime (min) Fluoroscopy Time (min) DAP (cGy/cm2) ED (mSv) LAR, % LAL 18 (2.8) 55 (45-98) 10 (8-14) 538 (313-706) 1.1 (0.8-1.5) 0.01 (0.008-0.02) LL 244 (38.4) 55 (45-75) 11 (8-17) 796 (480-1343) 1.8 (1.1-3.1) 0.02 (0.01-0.03) LPL 34 (5.4) 55 (44-81) 12 (7-17) 787 (483-1884) 1.9 (1.0-4.1) 0.02 (0.01-0.04) LP 22 (3.5) 58 (48-66) 13 (7-19) 1014 (456-1570) 2.3 (1.1-3.5) 0.02 (0.01-0.03) LPS 54 (8.5) 80 (55-106) 20 (10-29) 1637 (795-2384) 3.6 (1.8-5.3) 0.04 (0.02-0.05) RPS 173 (27.2) 60 (43-90) 13 (8-19) 988 (465-1609) 2.1 (1.1-3.6) 0.02 (0.01-0.04) RP 12 (1.9) 60 (36-94) 15 (7-26) 1372 (411-3420) 2.7 (0.8-8.2) 0.03 (0.01-0.08) RPL 24 (3.8) 69 (55-100) 19 (11-26) 1220 (738-2448) 3.5 (1.8-5.5) 0.04 (0.02-0.06) RL 27 (4.3) 90 (70-120) 27 (15-43) 1534 (848-2529) 3.6 (1.7-7.5) 0.04 (0.02-0.08) RAL 3 (0.5) 105 (45-105) 17 (11-17) 701 (288-701) 2.8 (0.6-2.8) 0.03 (0.005-0.3) RA 3 (0.5) 65 (60-65) 21 (18-21) 1596 (723-1596) 4.4 (1.5-4.4) 0.04 (0.01-0.4) AS/PH 19 (3.0) 65 (46-80) 15 (7-18) 555 (441-862) 1.2 (0.9-2.3) 0.01 (0.01-0.02) MS 2 (0.3) 100 (45-100) 21 (7-21) 1549 (377-1549) 3.1 (0.8-3.1) 0.01 (0.007-0.01 Total 635 (100.0) 60 (45-90) 13 (8-19) 889 (488-1660) 2.1 (1.1-3.7) 0.02 (0.01-0.04) Notes: LAL: left anterolateral; LL: left lateral; LPL: left posterolateral; LP: left posterior; LPS: left posteroseptal; RPS: right pos- teroseptal; RP: right posterior; RPL: right posterolateral; RL: right lateral; RAL: right anterolateral; RA: right anterior; RAS/PH: right anteroseptal/para-Hisian; HB: His bundle; MS: midseptal. Table 2. Change in procedure time and radiation indices over the study period Year Number Procedure time (mins) Fluoroscopy time (mins) DAP (cGy/cm 2) ED (mSv) LAR, % 2016 96 75 (51-94) 19 (11-25) 1254 (751-2527) 3.1 (1.6-5.8) 0.03 (0.02-0.06) 2017 149 75 (60-110) 17 (12-30) 1604 (789-2713) 3.5 (1.8-5.7) 0.04 (0.02-0.06) 2018 196 60 (45-80) 12 (9-17) 798 (445-1284) 1.8 (1.0-3.1) 0.02 (0.01-0.03) 2019 194 50 (40-65) 9 (6-12) 596 (335-1079) 1.4 (0.8-2.4) 0.01 (0.008-0.02) p-value <0.001 <0.001 <0.001 <0.001 <0.001 M. Ali et al. 31 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 The main findings of our study are: a. There was a significant increase in the number of catheter ablation procedures performed in our laboratory over the study period. b. The procedure time and the radiation indices (fluoroscopy time, DAP, ED, and LAR) significantly decreased over the study period (p<0.001 for all the parameters). c. The trend of a significant decrease in pro- cedure time and radiation exposure continued when the data were divided into two groups based on the fluoroscopy frame rate (p<0.001 for all the parameters). The radiation indices reported in different studies of catheter ablation procedures are pre- sented in Table 4. The radiation indices re ported are comparable to that of the published data. Injury caused by exposure to ionizing ra- diation can be classified into two groups: a) the deterministic effects and b) the stochastic effects. Deterministic effects are dose-de pen- dent (e.g., cataracts and skin injuries). A threshold radiation dose is a radiation dose below which the deterministic effects are not produced. On the other hand, even a tiny radiation dose involves an increased risk of stochastic effects (e.g., cancer), and the chances of suffering that effect are directly proportional to the radiation dose. As no radiation dose is safe, the policy of maintaining radiation exposure level is depen- dent on the “as low as reasonably achievable” (ALARA) principle. [4] Some of the factors that influence the extent of ionizing radiation exposure in a cardiac EP laboratory are: 1) Operator dependent: a) experience of the operators, b) training of operators with simulators, c) radiation awareness of the staff, d) C-arm projection used during the procedure, e) fluoroscopy frame rate, f) cine duration, g) cine substitution by stored fluoroscopy, h) fluoroscopy use during catheter removal from the body, i) collimation of the X-ray system, j) pelvic radiation, k) written report of the patient’s radiation exposure during the procedure. Table 3. Impact of fluoroscopy frame rate change on procedure time and radiation indices. Pre-group: procedures performed at 7.5 fps; post-group: procedures performed at 3.75 fps Number Procedure time (mins) Fluoroscopy time (mins) DAP (cGy/cm2) ED (mSv) LAR, % Pre 260 75 (55-104) 18 (12-27) 1432 (780-2564) 3.2 (1.8-5.7) 0.03 (0.02-0.06) Post 375 55 (40-75) 10 (7-15) 698 (392-1176) 1.6 (0.9-2.7) 0.02 (0.01-0.03) p-value <0.001 <0.001 <0.001 <0.001 <0.001 Table 4. Reported radiation exposure in catheter ablation of supraventricular tachycardias (SVT). Adapted from [9] Study Type of study Number of patients Fluoroscopy time (mins) DAP (cGy/cm 2) Effective Dose (mSv) Smith IR et al. [10] Retrospective AVNRT 270 AVRT 135 2.1 (1.3-4.5) 23.8 (13.4-45.3) 260 (170-610) 2690 (1600-5410) – Rogers DP et al. [7] Observational Pre DRM 147 (AVNRT/AVRT) Post DRM 257 (AVNRT/AVRT) – 2040±2690 800±1030 3.3 1.24 Heidbuchel H et al. [4] EHRA practical guide – – – 4.4 (1.6-25) Casella M et al. [6] Multicentre randomized Pre DRM 128 Post DRM 134 14.32 (9.08- 22.43) 0 (0-0.2) 2036 (54–5297) 278 (80–791) 8.87 (3.67–22.01) 0 (0–0.08) See J et al. [11] Observational Pre DRM AVRT 55 Post DRM AVRT 44 49.0 ± 36.3 14.1 ± 13.4 3292 ± 3282.7 654.4 ± 645.5 – Casella M et al. [9] Retrospective 979 (SVT) 13(6-21) 1721(727-3884) 4.1(1.8-9.1) Our data Retrospective Pre 260 Post 375 18 (12-27) 10 (7-15) 1432 (780-2564) 698 (392-1176) 3.2 (1.8-5.7) 1.6 (0.9-2.7) M. Ali et al. 32 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 2) Patient dependent: a) body habitus of the patient, b) arrhythmic lesion to be ablated. 3) Technology dependent: a) X-ray system, b) combination with computed tomography (CT), c) three-dimensional electroanatomic mapping systems, d) shielding of the laboratory personnel. [4] The factors that lead to decreased radiation exposure in the cardiac EP laboratory are: 1) Operator dependent: a) expert operators, b) operators who have been trained with simulators, c) radiation aware staff, d) predo- minant usage of right anterior oblique C-arm projection than an anteroposterior of left anterior oblique projection, e) low frame rate of fluoroscopy (<6 fps), f) short cine duration, g) frequent cine substitution by stored fluo- roscopy, h) catheter withdrawal from the body without using fluoroscopy, i) optimized and adapted collimation, j) avoidance of pelvic radiation, k) a written report of the patient’s radiation exposure that includes air kerma or dose area product received during the pro- cedure. 2) Patient dependent: lean body habitus of the patients, supraventricular tachycardia ablation than atrial fibrillation ablation or ventricular tachycardia ablation, 3) Technology dependent: cardiac EP tuned X-ray system which has been adequately maintained and inspected for quality control, no preprocedural or rotational computed tomography, the predominant use of three- dimensional electroanatomic mapping systems, proper shielding which includes above and below the table or cabin shielding [4]. One of the most efficient ways to decrease radiation exposure during the ablation of accessory pathways is to perform these procedures with the help of three-dimensional electroanatomic mapping, which has been shown to decrease radiation exposure in such procedures significantly. No-Party trial was the first multicentre, prospective, randomized trial that compared conventional fluoroscopy-guided catheter ablation procedures with procedures performed using the three-dimensional electroanatomic mapping system in the patients undergoing EP study for supraventricular tachycardias, 36% of whom were AP ablation procedures [6]. In this trial, three-dimensional electroanatomic mapping significantly reduced fluoroscopy time and ED (0 seconds and 0 mSv) when compared to the procedures performed under fluoroscopic guidance (859 seconds and 8.87 mSv) (p<0.00001). But the use of three-dimensional electro- anatomic mapping systems is restricted due to various logistic reasons (availability, lack of expertise); we need to find alternative ways to decrease radiation exposure during catheter ablation procedures [4]. Rogers A J et al. conducted a study to evaluate the effect of radiation dose-reduction maneuver on the radiation exposure in EP laboratory. Atrioventricular nodal reentrant and AP-mediated tachycardia was 64% of catheter ablation procedures. They showed that with the simple maneuver of removing a secondary radiation grid to improve image quality and reducing the fluoroscopy pulse rate from 12.5 to 6.25 pulses/second, a radiation dose reduced from 20.4 to 8.0 Gycm2. Additionally, the risk of radiation-related fatal malignancy was reduced by 63 due to the implementation of the maneuver. This study showed the importance of selecting electrophysiology laboratory parameters in reducing radiation exposure during catheter ablation procedures [7]. Voskoboinik A et al. conducted a prospective study to analyze the trends in radiation exposure during AF ablation at a single center over 12 years. A significant and progressive decrease in the fluoroscopy time and ED was observed over time. The significant decrease in the patient and operator radiation exposure was attributed to increased operator experience, higher annual case volume, technology evolution over time, and recent use of contact force-sensing catheters. [8] More recently, Casella M et al. have reported fluoroscopy data from their retrospective analysis of various EP and device implantation procedures at a large volume laboratory over 7 years. Fluoroscopy time, DAP, and ED showed a statistically significant reduction trend for all EP procedures. Based on the obtained results, it was proposed that a combination of operator awareness about the fluoroscopy-associated risk and technological advancement can be used for optimizing the use of fluoroscopy in EP procedures [9]. One of the significant limitations of this study, other than being a retrospective analysis, is that one can argue that a significant decrease in the procedure duration can solely explain the changes in the radiation exposure in the procedure time, which is also reflected in the decrease in the fluoroscopy time. If there is a significant decrease in the procedure time, the radiation exposure will automatically decrease. M. Ali et al. 33 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 Some of the other limitations of this study are that data regarding some of the other factors that influence radiation exposure during procedures (e.g., body mass index of the patients, cine exposure duration during the procedures) performed under fluoroscopy was not available. This study is based on retrospective data collected from a single center, and the results cannot be generalized to other centers. As already alluded to, radiation exposure also depends on the individual expertise of operators, but data regarding the radiation exposure of individual operators was not available. We propose that in our study, the decrease in the radiation indices is not solely because of the reduction in fluoroscopy frame rate but because of other factors, too, one being a more than 200% increase in the yearly number of ablation procedures performed over the study period. Any modern electrophysiology labo- ratory will face the same scenario. Conclusions A reduction in the fluoroscopy frame rate and improvement in the electrophysiology laboratory workflow leads to a significant decrease in the radiation exposure during catheter ablation procedures of accessory pathway-mediated tachycardias. Conflict of interest The authors declare no conflict of interest. Authors’ contributions Muzaffar Ali: formal analysis, writing – original draft, investigation, formal analysis. Bharatraj Banavalikar: writing – reviewing and editing, investigation, formal analysis. Milan Kumar Ghadei: formal analysis, writing – original draft, investigation, formal analysis. Anju Kottayan: formal analysis, writing – original draft, investigation, formal analysis. Deepak Padmanabhan: writing – reviewing and editing, investigation, formal analysis. Jayaprakash Shenthar: conceptualization, methodology, writing – reviewing and editing ІОНІЗУюЧЕ ОПРОМІНЕННЯ ПРИ РАДІОЧАСТОТНІй АБЛЯЦІЇ ДОДАТКОВИХ шЛЯХІВ ПРОВЕДЕННЯ У ЕЛЕКТРОфІЗІОЛОГІЇ СЕРЦЯ: РЕТРОСПЕКТИВНИй АНАЛІЗ *M. Ali1,2, B. Banavalikar1, M.K. Ghadei1, A. Kottayan1, D. Padmanabhan1, J. Shenthar1 1 – DEPARTMENT OF CARDIAC ELECTROPHYSIOLOGY, SRI JAYADEVA INSTITUTE OF CARDIOVASCULAR SCIENCES AND RESEARCH, BANGALORE, INDIA 2 – DEPARTMENT OF CARDIOLOGY, SHER-I-KASHMIR INSTITUTE OF MEDICAL SCIENCES, SRINAGAR, KASHMIR, INDIA Вступ. Радіочастотна катетерна абляція (КА) метод вибору лікування у пацієнтів з тахікардією, додатковими шляхами (ДШ). Більшість таких процедур проводиться під флюо роскопічним наглядом, що призводить до значного опромінення пацієнта та персоналу лабораторії. У цьому аналізі ми розглянули радіаційне опромінення в процедурах КАДШ, виконаних без підтримки тривимірної системи електроанатомічного відображення. Ми проаналізували зміни показників експозиції за період дослідження та вплив зміни частоти кадрів флюороскопії (FFR). Мета. Метою цього дослідження є (1) кількісна оцінка радіаційного опромінення в процедурах абляції додаткових шляхів, (2) аналіз тенденції радіаційного опромінення з часом та (3) оцінка впливу зменшення частоти кадрів флюороскопії на показники радіаційного опромінення під час цієї процедури. Методи. Ми ретроспективно проаналізували всі процедури абляції ДШ, проведені в нашому інституті з січня 2016 року по грудень 2019 року. Зібрані дані: вік, стать, місце розташування ДШ на основі успішного місця абляції на флюороскопії, час процедури, час флюороскопії та індекс доза опро- мінення відносно площі (DAP). Ефективну дозу (ЕД) оцінювали за DAP. Дані процедур, проведених до січня 2018 р. (група “До”), порівнювались із даними процедур, проведених після цієї дати (група “Після”). Процедури групи “До” виконувались із частотою FFR 7,5 кадрів в секунду (fps), а процедури групи “Після” – з частотою FFR 3,75 fps. Результати. Загальна кількість процедур, включених до аналізу, становила 635. Середній вік пацієнтів становив 39±14 років, і 401 з них (63%) були чоловіками. Найчастіше зустрічалися ліво- латеральні ДШ (38%). Показники тривалості процедури та опромінення зменшилися протягом періоду дослідження (р<0,001). Процедури групи “Після” мали значно коротший час проведення КА та менший радіаційний вплив, ніж процедури групи “До”. Висновки. Зменшення FFR було пов'язане зі значним зменшенням радіаційного опромінення в процедурах абляції ДШ. КЛЮЧОВІ СЛОВА: додаткові шляхи проведення; катетерна абляція; дозування опромінення; час флюороскопії; радіаційне опромінення. M. Ali et al. 34 IN T E R N A L m E d Ic IN E ISSN 2413-6077. IJmmR 2021 Vol. 7 Issue 1 Information about the authors Muzaffar Ali MD, DM: Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. ORCID 0000-0002-3489-5864, email: dralmuzaffar@gmail.com Bharatraj Banavalikar MD, DM: Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. ORCID 0000-0003-1116-3967, email: bharatrajnb@gmail.com Milan Kumar Ghadei MD, DM: Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. dr.milan80@gmail.com Anju Kottayan BSc: Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. anjukottayan@gmail.com Deepak Padmanabhan MD, DM: Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. ORCID 0000-0002-9127-9275, email: deepak.padmanabhan@gmail.com Jayaprakash Shenthar MD, DM, FACC, FRCP (Lond): Department of Cardiac Electrophysiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. ORCID 0000-0003-4509-7515, email: jpsbhat@gmail.com References 1. Borggrefe M, Budde T, Podczeck A, Breithardt G. High frequency alternating current ablation of an accessory pathway in humans. 10:7. DOI: 10.1016/ s0735-1097(87)80200-0 2. Page RL, Jogler JA, Caldwell MA. 2015 ACC/AHA/ HRS guideline for the management of adult patients with supraventricular tachycardia. Heart Rhythm. 2015;13(4):86. DOI: 10.1016/j.hrthm.2015.09.019 3. Katritsis DG, Arbelo E, Arribas F. The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC). Eur Heart J. 41(2020):655–720. DOI: 10.1093/ eurheartj/ehz467 4. Heidbuchel H, Wittkampf FHM, Vano E, Ernst S, Schilling R, Picano E, et al. 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