








key: cord-282499-baia5prj
authors: Lei, Pinggui; Fan, Bing; Yuan, Yingnan
title: The evolution of CT characteristics in the patients with COVID-19 pneumonia
date: 2020-03-19
journal: J Infect
DOI: 10.1016/j.jinf.2020.03.014
sha: 
doc_id: 282499
cord_uid: baia5prj

nan

In that study, significant statistical differences were observed in CT features of peripheral involving central ( P = 0.028), consolidation ( P = 0.009), and thickened interlobular septa ( P = 0.040) between moderate ( n = 28) and sever/critically severe ( n = 13). 1 We would like to share our opinions about the evolution of radiological features in the patients with COVID-19 infection. Actually, the CT features are various at different stages in the patients with COVID-19 infection.

Currently, the "gold standard" is real-time reverse transcriptase polymerase chain reaction (RT-PCR) amplification of the viral DNA for diagnosis of COVID-19 infection. However, Medical imaging is of great significance in the detection and surveillance of COVID-19 infection. Recently, the studies demonstrated that the CT findings were typical signs for diagnosis at different stages of COVID-19 pneumonia. 3 , 4 Particularly, ground glass opacities (GGO) and consolidation were the principal manifestation in the CT images (CT scans before onset of symptoms or CT scans done ≤ 1 week after symptom onset), and GGO was decreased with increasing the stages of COVID-19 pneumonia. However, the consolidation or GGO mixed consolidation increased, and reticular was also observed in the later stages (scan > 1 week after symptom onset). Pleural effusion or lymphadenopathy was rarely seen. 4 CT features were distributed primarily in the lower lobes and subpleural (especially in the right lower lobe), 4 , 5 with rapid evolution from focal unilateral pulmonary parenchyma to diffuse bilateral GGO or GGO with consolidation within 1-3 weeks. 4 Therefore, knowing the corresponding CT feature of COVID-19 pneumonia at different stages, which could be helpful to precisely diagnose and understand CT characteristics of the novel coronavirus pneumonia beyond the radiological findings itself.

In conclusion, there were some CT characteristics concerning the location of lesion, GGO, consolidation, etc. detected in the patients with COVID-19 pneumonia. However, the evaluation of pri-mary CT findings in COVID-19 pneumonia is various at different stages.

None.

Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2

Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):a multi-center study in Wenzhou city

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Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study

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