i 
 

HISTOPATHOLOGY IMAGES 
 

Endometrial Stromal Sarcoma 
 
 

 
Figure 1: Gross presentation of endometrial stromal 
sarcoma. Intact bicornuate uterus appears heart -
shaped. 
 

 
Figure 3: Microscopic view of endometrial stromal 
sarcoma with marked pleomorphic nuclei and marked  
mitosis (arrow) (H&E, 400x). 

 
Figure 2: Endometrial stromal sarcoma. Cut surface of  
uterus shows large necrotic mass obliterating the 
endometrial cavity and reaching up to isthmus. 
 

 
Figure 4: Microscopic view of high grade endometrial 
stromal sarcoma infiltrating the bundle of myometrium 
(arrow) (H&E, 100x). 

 
 
 
 



ii 
 

Metaplastic Carcinoma of Breast 
 

 

 
Figure 1: Gross appearance of mastectomy specimen  
with large prominent lump. 

 

 
Figure 3: Microscopic examination reveals pure 
squamous cell carcinoma–metaplastic carcinoma of  

breast (H&E, 100x). 

 

 
Figure 2: Cut surface of mastectomy specimen showin g 
large necrotic mass with hemorrhagic areas. 
 

 
Figure 4: Metaplastic carcinoma of breast showing nests 
of squamous cells infiltrating the stroma (H&E, 100x). 

 

 

 

 

 

 

Contributed by: 
 
Department of Pathology 
Dr. Akbar Niazi Teaching Hospital, Islamabad