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Histopathology Images 

 

Melanoma 

  
Figure 1: Gross appearance of Melanoma. Skin with 
large protruded pigmented lesion measuring 
approximately 2cm in high. 
 

Figure 2: Microscopic view of melanoma cell nest with 
abundant melanin. The cells appear markedly 
pleomorphic (H&E 400). 
 

  
Figure 3: Nest of Melanotic cells with melanin. Figure 4: High power microscopic view showing nest of 

melanotic cells with blackish melanin pigmentation. 

 



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Polypoidal Leiomyoma 

  
Figure 1: Cut surface of leiomyoma with myxoid 
degeneration. 

Figure 2: Large polypoid leiomyoma hanging from the 
cervical cavity. 

  
Figure 3: Microscopic view. Fascicles of smooth 
muscles cells with myxoid stroma (H&E 100). 

Figure 4:  Fascicles of smooth muscles with bland 
looking cells and myxoid areas (H&E 100). 

 

Contributed by: 
 

Prof Dr. Saeed Alam, Dr. Javeria Faridi 
Department of Pathology, Islamabad Medical & Dental College