EDITORIAL Artificial Intelligence in Dentistry: Hype or Hope? Ulfat Bashir, Kanwal Zulfiqar Artificial intelligence is one of the most significant contributions to the fourth industrial revolution, which ushers in a new digital era. It is defined as “the study of intelligent agents, which includes any machine that can comprehend its environment and 1 respond to increase its chances of success.” The term "AI" is used informally when a machine imitates cognitive processes that people often connect with other human minds, such as "learning and problem- 1 solving." Mathematician John McCarthy created the concept of "artificial intelligence" in 1955. McCarthy is widely considered the founder of the field. To explain how machines might be able to perform what can be referred to as "intelligent" activities, he 2 introduced this phrase. Numerous industrial sectors, including robotics, transportation, smart cities, financial analysis, etc., have incorporated AI. As an example, medical and dental imaging diagnostics, decision support, precision and digital medicine, drug discovery, wearable technologies, hospital monitoring, robotic and virtual assistants have all been employed in medicine and dentistry. In many instances, artificial intelligence (AI) can be seen as a helpful tool for physicians and dentists to lessen their labor. AI may learn from various information sources (multi-modal data) to diagnose diseases beyond the capability of humans, in addition to identifying diseases by means of a single information source that 3 is focused on a particular illness. The introduction of AI platforms such as CHAT GPT has completely revolutionized the dynamics of information being available within seconds. Similarly, health professionals are eagerly contemplating its 3 effects in the Medical and Dental Health profession. The dentists all over the world are also rapidly embracing the advancements in AI and machine 4 learning. One of the biggest advantages of AI in dentistry is its ability to diagnose oral diseases with high accuracy and precision. AI algorithms can analyze dental images and detect early signs of oral cancer, periodontitis, and other oral diseases, allowing for early treatment and prevention of 5 further complications. AI has been heavily utilized in periodontology to investigate, comprehend, and build periodontal applications, such as detecting periodontal bone loss, identifying gingivitis inflammation, and evaluating connective tissues and other periodontal 4 cavities. Endodontic treatment planning has been greatly aided by AI in recent years. Different types of AI can aid dentists in the diagnosis and management of endodontic issues while fostering performance and assuring improved and precise patient care. The review's main objectives are to extract and evaluate AI-based methods for disease diagnosis and therapy 4 planning. When teeth exhibit periapical lesions and/or associated symptoms, it may be challenging for doctors to make a diagnosis and formulate a 6 treatment plan. The common disease known as apical periodontitis is responsible for about 75% of 7 cases with radiolucent jaw lesions. Early detection could improve the effectiveness of care, stop it from spreading to other tissues, and lessen potential 8 difficulties. Another benefit of AI in dentistry is its ability to improve the planning and execution of 5 dental procedures. AI algorithms can help dentists plan complex procedures such as implants, orthodontics, and restorations with high accuracy, reducing the risk of complications and ensuring the 4 best possible outcome for the patient. Due to its capacity to improve the efficiency and accuracy of the diagnostic process, artificial intelligence (AI) has become extremely popular in orthodontics in recent years. Since orthodontic treatments are frequently drawn-out processes, more effective planning calls for more effective and efficient solutions. Dentists can make judgments more precisely and quickly in a time-constrained context by using AI-based knowledge to automate disease diagnosis and treatment prognosis processes. Through their capacity to learn and make Correspondence: Prof. Ulfat Bashir Department of Orthodontics Islamic International Dental College, Riphah International University Islamabad E-mail: ulfat.bashir@riphah.edu.pk Received: February 27,2023; Accepted: March 01, 2023 1 Department of Orthodontics Islamic International Dental College, Riphah International University Islamabad https://doi.org/10.57234/jiimc.march23.1666 automobile decisions, AI solutions can further aid in the prevention of human errors. Numerous studies have looked into using AI to diagnose and design 9,10 treatments for orthodontic diseases. In the area of dental education, AI is extensively used. The preclinical virtual patient input to the students has been much enhanced. The interactive interphase develops top-notch learning environments by letting pupils assess their own work and contrast it with the ideal. Numerous studies on the efficiency of these systems have revealed that, in comparison to conventional simulator units, these systems enable students to reach a competency-based skill level 11 more quickly. Artificial intelligence-powered virtual dental assistants can perform a variety of tasks in dental offices with greater accuracy and fewer errors. It is very helpful when discussing the patient's medical history and any habits they may have, such as smoking and drinking, with the dentist. The patient can choose to receive urgent teleassistance in dental crises, particularly if the practitioner is not 12 readily available. In recent years, there has been a noticeable increase in the number of research investigating the 13,14 application of AI in restorative dentistry. Various studies investigated the application of AI in helping caries detection, vertical tooth fracture prediction, and treatment planning. To accurately plan therapy utilizing clinical examples, Lee et al. suggested a machine learning method based on a decision tree to evaluate the tooth prognosis. The model's precision 13 was 84.1%. However, despite the rapid progress made in AI research in dentistry, there are still many challenges that need to be addressed. One of the biggest challenges is the lack of data standardization and interoperability between AI systems and existing dental systems. Also there is lack of understanding and adoption by dental professionals. While some dentists have embraced AI and its benefits, others are still skeptical about the technology and its ability to replace human expertise. Additionally, the high cost of AI technology can also limit its widespread adoption, particularly in resource-limited settings like Pakistan. This can lead to the inability to share data and collaborate on research thus limiting the advancement of the field. Additionally, there is a need for further research on the ethical and legal implications of AI in dentistry, such as data privacy and patient consent. It is still necessary to use appropriate external data gathered from freshly enrolled patients or gathered from other dental facilities to confirm the generalizability and dependability of the offered AI models, even though their results have been 15 encouraging. Administration and exchange of clinical data are two major barriers to the use of AI systems in the healthcare sector. Patients' personal data is needed for both the initial training of AI algorithms as well as for ongoing training, validation, and improvement. The development of AI will also promote data sharing across multiple institutions and, in some circumstances, across international borders. AI must be integrated into healthcare operations while modifying systems that protect 16 patient confidentiality and privacy. Personal data must therefore be anonymized before considering a 17 wider distribution. Even if these protections are technically possible, the medical community has doubts about secure data sharing. Despite these limitations, the future of AI in dentistry looks bright. As AI technology continues to advance and become more accessible, we can expect to see an increased adoption of the technology by dental professionals and patients alike. Furthermore, the development of AI-powered devices and tools will revolutionize the way dentists diagnose and treat oral diseases, leading to improved patient outcomes and a more efficient and effective delivery of dental care. computer learning Researchers will be better able to comprehend some multifactorial diseases with the aid of deep learning, and it will be feasible to increase our collective understanding of oral diseases and conditions that are not yet fully known. Artificial intelligence can undoubtedly be a tool for delivering improved healthcare to patients, but it cannot in any way take the place of human knowledge, skills, and 18 capacity of judgment. Despite the difficulties, there is a good probability that AI will be used in dentistry in the future, and as we adopt these exciting innovations, patient care will only improve. However, for this to happen in the dental sector, new finance resources are required, along with debt and an understanding that open systems lead to innovations that are good for the sector. The possibilities are endless if these problems can be fixed. In conclusion, AI is the next paradigm shift in the healthcare. We as healthcare JIIMC 2023 Vol. 18, No.1 2 Artificial Intelligence in Dentistry https://doi.org/10.57234/jiimc.march23.1666 professionals need to carefully evaluate the challenges we face when moving towards this new age of transformation.AI is not absolute and cannot replace human judgement. It is imperative that we adapt to AI to improve patient care but also be watchful of its limitations. REFERENCES 1. Russel S, Norvig P. Artificial Intelligence: A Modern Approach. 3rd ed. New Jersey: Pearson Education; 2010. Back to cited text no. 2. 2. Rajaraman V. John McCarthy—Father of artificial intelligence. Resonance. 2014 Mar;19:198-207. 3. Poplin R, Varadarajan AV, Blumer K, Liu Y, McConnell MV, Corrado GS, et al. Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning. Nat Biomed Eng. (2018) 2(3):158–64. Doi: 10.1038/s41551- 018-0195-0 PubMed Abstract | CrossRef Full Text | Google Scholar. 4. Fatima A, Shafi I, Afzal H, Díez ID, Lourdes DR, Breñosa J, Espinosa JC, Ashraf I. Advancements in Dentistry with Artificial Intelligence: Current Clinical Applications and Future Perspectives. InHealthcare 2022 Oct 31 (Vol. 10, No. 11, p. 2188). MDPI. 5. Agrawal P, Nikhade P. Artificial Intelligence in Dentistry: P a s t , P r e s e n t , a n d F u t u r e . C u r e u s . 2 0 2 2 J u l 28;14(7):e27405. doi: 10.7759/cureus.27405. PMID: 36046326; PMCID: PMC9418762. 6. Artificial intelligence in endodontics: Current applications and future directions. Aminoshariae A, Kulild J, Nagendrababu V. J Endod. 2021;47:1352–1357. [PubMed] [Google Scholar]. 7. Radiolucent inflammatory jaw lesions: a twenty-year analysis. Becconsall-Ryan K, Tong D, Love RM. Int Endod J. 2010;43:859–865. [PubMed] [Google Scholar]. 8. Periapical lucency around the tooth: radiologic evaluation and differential diagnosis. Chapman MN, Nadgir RN, Akman AS, Saito N, Sekiya K, Kaneda T, Sakai O. Radiographics. 2013;33:0–32. [PubMed] [Google Scholar]. 9. Khalid MA, Zulfiqar K, Bashir U, Shaheen A, Iqbal R, Rizwan Z, Rizwan G, Fraz MM. 'Aariz: A Benchmark Dataset for Automatic Cephalometric Landmark Detection and CVM Stage Classification. arXiv preprint arXiv:2302.07797. 2023 Feb 15. 10. Chen S., Wang L., Li G., Wu T.H., Diachina S., Tejera B., Kwon J.J., Lin F.C., Lee Y.T., Xu T., et al. Machine learning in orthodontics: Introducing a 3D auto-segmentation and auto-landmark finder of CBCT images to assess maxillary constriction in unilateral impacted canine patients. Angle Orthod. 2020;90:77–84. doi: 10.2319/012919-59.1. [PMC free article] [PubMed] [CrossRef] [Google Scholar]. 11. Artificial intelligence: transforming dentistry today. Khanna S S , D h a i m a d e PA . h t t p s : / / w w w. i j b a m r. c o m / assets/images/issues/pdf/June%202017%20161167.pdf.p df Indian J Basic Appl Med Res. 2017;6:161–167. [Google Scholar]. 12. Artificial Intelligence in Dentistry: Current Concepts and a Peep into the Future. Alexander B, John S. Int J Adv Res. 2018;30:1105–1108. [Google Scholar]. 13. Lee S.J., Chung D., Asano A., Sasaki D., Maeno M., Ishida Y., Kobayashi T., Kuwajima Y., Da Silva J.D., Nagai S. Diagnosis of Tooth Prognosis Using Artificial Intelligence. Diagnostics. 2022;12:1422. doi: 10.3390/diagnostics12061422. [PMC free article] [PubMed] [CrossRef] [Google Scholar]. 14. Abdalla-Aslan R., Yeshua T., Kabla D., Leichter I., Nadler C. An artificial intelligence system using machine-learning for automatic detection and classification of dental restorations in panoramic radiography. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2020;130:593–602. doi: 10.1016/j.oooo.2020.05.012. [PubMed] [CrossRef] [Google Scholar]. 15. The use and performance of artificial intelligence applications in dental and maxillofacial radiology: A systematic review. Hung K, Montalvao C, Tanaka R, Kawai T, B o r n s t e i n M M . D e n t o m a x i l l o f a c R a d i o l . 2020;49:20190107. [PMC free article] [PubMed] [Google Scholar]. 16. Char DS, Shah NH, Magnus D. Implementing machine learning in healthcare — addressing ethical challenges. N Eng J Med. 2018;378(11):981-3. 17. He J, Baxter SL, Xu J, Xu J, Zhou X, Zhang K. The practical implementation of artificial intelligence technologies in medicine. Nat Med. 2019 Jan;25(1):30-36. doi: 10.1038/s41591-018-0307-0. Epub 2019 Jan 7. PMID: 30617336; PMCID: PMC6995276. 18. Israni ST, Verghese A. 2019. Humanizing artificial intelligence. JAMA. 321(1):29–30. JIIMC 2023 Vol. 18, No.1 3 Artificial Intelligence in Dentistry CONFLICT OF INTEREST Authors declared no conflicts of Interest. GRANT SUPPORT AND FINANCIAL DISCLOSURE Authors have declared no specific grant for this research from any funding agency in public, commercial or nonprofit sector. DATA SHARING STATMENT The data that support the findings of this study are available from the corresponding author upon request. This is an Open Access article distributed under the terms of the Creative Commons Attribution- Non- Commercial 2.0 Generic License. https://doi.org/10.57234/jiimc.march23.1666