id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
jnps-42865	Gupta, Aparajita; Roy, Shuvendu ; Paul, Prateep	Effectiveness of Pyridostigmine and Pyridoxine in Vinca AlkaloidInduced Cranial Neuropathy – A Case Series	2022-12-31	3	.pdf	application/pdf	1789	99	48	The time course of onset of the cranial neuropathies in relation to the initiation of Vinca alkaloid therapy, normal CSF and MRI brain, complete resolution of the symptoms with pyridoxine and pyridostigmine and absence of recurrence of symptoms on withholding further Vinca alkaloid-based therapy lends credence to the diagnosis of a pure drug induced toxic neuropathy in all our cases. However, the use of Vinca alkaloids is restrained by the development of dose related slowly progressive peripheral sensorimotor neuropathy which mandates delay or change in the treatment protocols as well as dose reductions.	cache/jnps-42865.pdf	txt/jnps-42865.txt
