item: #1 of 284 id: jovr-10163 author: Dalvin, Lauren A title: Editorial – Thiolated Chitosan-carboxymethyl Dextran Nanoparticles: Improving Intravitreal Drug Bioavailability for Retinoblastoma date: 2022-01-21 words: 1731 flesch: 38 summary: With current standard of care therapy, globe salvage can be achieved even for the most advanced group E eyes in about 50% of cases.[5] Delrish et al describe what may be the next frontier in intravitreal chemotherapy delivery, with improved drug bioavailability using thiolated chitosan-carboxymethyl dextran nanoparticles (CMD-TCs-NPs). Although this was a small study with 10 rats, Delrish et al concluded that surface charge is a key factor determining vitreous diffusion and retinal penetration for chitosan-derived intraocular drug-delivery mechanisms, and they propose future use of thiolated chitosan derivatives for intravitreal chemotherapy delivery aimed at retinoblastoma treatment.[1] keywords: chitosan; delivery; drug; nanoparticles; retinoblastoma; vitreous cache: jovr-10163.pdf plain text: jovr-10163.txt item: #2 of 284 id: jovr-10164 author: Jha, Ashok; Simba, Abhay title: Conjunctival Autograft versus Combined Amniotic Membrane and Mini-Simple Limbal Epithelial Transplant for Primary Pterygium Excision date: 2022-01-21 words: 4728 flesch: 57 summary: A total of 264 consecutive eyes of 264 patients were enrolled in the study, of which 31 eyes (15 in CAG and 16 in mini-SLET groups) were ruled out due to inadequate follow-up. The mean operative time for mini-SLET group (20.33 ± 1.28 min) was significantly higher (P < 0.001) than the CAG group (12.01 ± 1.26 min). keywords: cag; day; excision; group; limbal; mini; patients; pterygium; recurrence; slet cache: jovr-10164.pdf plain text: jovr-10164.txt item: #3 of 284 id: jovr-10165 author: Salouti, Ramin; Khosravi, Amir; Fardaei, Majid; Zamani, Mohammad; Nejabat, Mahmoud; Ghoreyshi, Maryam; Salouti, Kia; Nowroozzadeh, M. Hossein title: Inferior Spear-like Lens Opacity as a Sign of Keratoconus date: 2022-01-21 words: 3639 flesch: 52 summary: Results: Overall, 2122 out of 33,368 cases (6.4%) without lens opacity had keratoconus, while 20 out of 21 patients (95.2%) with peculiar lens opacity had definite keratoconus (P < 0.001). Lens opacity was bilateral in 5 cases (24%), and keratoconus was bilateral in all 20 patients with lens opacity. keywords: feather; keratoconus; lens; lens opacity; opacity; patients; shape cache: jovr-10165.pdf plain text: jovr-10165.txt item: #4 of 284 id: jovr-10166 author: Bamdad, Shahram; Razavizadegan, Seyyed Ahmad; Farvardin, Mohsen; Mohaghegh, Sahar title: Vision-related Quality of Life after Bilateral Implantation of Monofocal and Multifocal Intraocular Lenses date: 2022-01-21 words: 4765 flesch: 48 summary: However, if the traditional group were served by PanOptix, this resultant satisfaction may not be obtained, as PanOptix intraocular lens requires making an adjustment for the near vison which easygoing patients may find inconvenient. Keratometry and axial length measurements with intraocular lens Master 500 (Carl Zeiss Meditec, Germany) was performed prior to the surgery for all patients. keywords: cataract; intraocular; lens; lenses; life; panoptix; patients; quality; surgery; vision; visual cache: jovr-10166.pdf plain text: jovr-10166.txt item: #5 of 284 id: jovr-10167 author: Nicolela Susanna, Carolina; Nicolela Susanna, Bianca; Nicolela Susanna, Fernanda; Susanna Jr, Remo title: Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity date: 2022-01-21 words: 3408 flesch: 58 summary: Distribution of number of eyes, mean MD, and mean IOP peak value of eyes according to the time of IOP peak in the WDT Time of IOP peak Number of eyes MD value (dB)† IOP peak (mmHg)† 15 20 (20.4%) –4.36 ± 5.51 17 ± 4 30 42 (42.9%) –9.35 ± 7.98 19 ± 3 45 36 (36.7%) –9.13 ± 8.56 19 ± 5 †Presented as mean ± standard deviation, calculated using summary statistics. Results of the mixed model evaluating the association between the MD and time of IOP peak, IOP peak value, and number of medications. keywords: drinking; glaucoma; iop; patients; peak; susanna; test; time; water; wdt cache: jovr-10167.pdf plain text: jovr-10167.txt item: #6 of 284 id: jovr-10168 author: Shetty, Vijay; Sankhe, Prachi; Haldipurkar, Suhas S; Haldipurkar, Tanvi; Dhamankar, Rita; Kashelkar, Priyanka; Shah, Dhruven; Mhatre, Paresh; Singh Setia, Maninder title: Diagnostic Performance of the PalmScan VF2000 Virtual Reality Visual Field Analyzer for Identification and Classification of Glaucoma date: 2022-01-21 words: 4362 flesch: 58 summary: The Palm Scan VF 2000® VR Visual Field Analyzer (MMD/USA) has an occluder within the system. Thus, the sensitivity and specificity for Palm Scan VF 2000® VR Visual Field Analyzer for classifying individuals as glaucoma/non-glaucoma was 100%. keywords: analyzer; field; glaucoma; hfa; palm; reality; scan; usa cache: jovr-10168.pdf plain text: jovr-10168.txt item: #7 of 284 id: jovr-10169 author: Venkatesh, Ramesh; Pereira, Arpitha; Jain, Kushagra; Kumar Yadav, Naresh title: Structural and Functional Outcomes of Surgery for Lamellar Macular Holes with or without Epimacular Proliferations date: 2022-01-21 words: 5258 flesch: 53 summary: Ramesh Venkatesh: https://orcid.org/0000-0002-4479-9390 Abstract Purpose: To compare the clinical, optical coherence tomography (OCT) features, and surgical outcomes of lamellar macular hole (LMH) depending on the presence of epimacular membrane proliferation (EMPF). Results: Lamellar macular hole without and with EMPF was noted in 62 (55%) and 50 (45%) eyes, respectively. keywords: acuity; empf; epiretinal; erm; eyes; hole; lamellar; lmh; oct; presence; study; surgery cache: jovr-10169.pdf plain text: jovr-10169.txt item: #8 of 284 id: jovr-10170 author: Darbari, Ensieh; Ahmadieh, Hamid; Rezaei Kanavi, Mozhgan ; Suri, Fatemeh; Elahi, Elahe title: Mutation Screening of Six Exons of ABCA4 in Iranian Stargardt Disease Patients date: 2022-01-21 words: 4173 flesch: 58 summary: Correlating the expression and functional activity of ABCA4 disease variants with the phenotype of patients with Stargardt disease. ABCA4 mutations are the usual cause of STGD1. keywords: abca4; disease; exons; gene; mutations; patients; research; stargardt cache: jovr-10170.pdf plain text: jovr-10170.txt item: #9 of 284 id: jovr-10171 author: Delrish, Elham; Ghassemi, Fariba; Jabbarvand, Mahmoud; Lashay, Alireza; Atyabi, Fatemeh; Soleimani, Masoud; Dinarvand, Rassoul title: Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma date: 2022-01-21 words: 5872 flesch: 53 summary: Our study has revealed that appropriate surface charges (preferably +11 ± 2.27 mV) on the surface of nanoparticles NPs that were manufactured with different chitosan derivatives may boost their diffusion after IVT injection. TCs could self-assemble into 34 nm NPs and with +11mV surface charges, while TMC NPs assembled into 42 nm NPs with a +29 mV zeta potential. keywords: cells; chitosan; cmd; cy5; delivery; drug; eye; figure; injection; nanoparticles; nps; research; retinoblastoma; surface; tcs; tmc; vitreous cache: jovr-10171.pdf plain text: jovr-10171.txt item: #10 of 284 id: jovr-10172 author: Fernandes Costa, Marcelo ; Dutra Henriques, Leonardo ; Côrrea Pinho, Otávio title: Development of a Spatio-temporal Contrast Sensitivity Test for Clinical Use date: 2022-01-21 words: 5179 flesch: 57 summary: Conclusion: We developed an approach to investigate the spatiotemporal integration of contrast sensitivity designed for clinical purposes. Tolerance limits of contrast sensitivity for normality ranges Spatial frequency Tolerance limits 0.5 cps 7.5 cps 15 cps 0.5 cpd Upper 240.3 492.2 239.1 Lower 108.2 173 87.3 10 cpd Upper 202.5 127.9 50.5 Lower 24.8 24.6 18.8 cpd, cyle per degree; cps, cycle per second Figure 2. keywords: clinical; contrast; costa; cpd; cps; frequencies; frequency; res; second; sensitivity; test; vision; visual cache: jovr-10172.pdf plain text: jovr-10172.txt item: #11 of 284 id: jovr-10173 author: Mohammadi, Seyed Farzad; Farzadfar, Farshad; Mehdi Pour, Parinaz ; Ashrafi, Elham; Lashay, Alireza; Mohajer, Bahram; Asadi Lari, Mohsen title: Prevalence and Burden of Refractive Errors at National and Sub-national Levels in Iran date: 2022-01-21 words: 4275 flesch: 50 summary: The Burden of Refractive Errors (Per 100,000) Refractive errors contributed to 441.41 and 348.38 YLDs in men and women, respectively. Refractive errors prevalence at national level by sex and age group from 1990 to 2018. and hyperopia conditions fluctuates to a higher level during the middle aged category of the population which is clearly reflected in the study diagrams. keywords: age; burden; data; errors; iran; myopia; national; prevalence; research; study; years cache: jovr-10173.pdf plain text: jovr-10173.txt item: #12 of 284 id: jovr-10175 author: Arabi, Amir; Tadayoni, Ramin; Ahmadieh, Hamid; Shahraki, Toktam; Nikkhah, Homayoun title: Update on Management of Non-proliferative Diabetic Retinopathy without Diabetic Macular Edema; Is There a Paradigm Shift? date: 2022-01-21 words: 6589 flesch: 47 summary: Furthermore, the incidences of sustained blindness in severe NPDR patients were reduced with anti- VEGF therapy by 57.7% over a 10-year follow-up period.[54] The phase-2 BOULEVARD trial compared the efficacy of Faricimab, a bispecific antibody, inhibiting both VEGF-A and angiopoietin-2, with ranibizumab in the treatment of patients with DME.[55] At the six-month follow-up period, among the patients who were treatment-naïve, 2-steps or greater improvement in the DRSS was achieved in 12.2%, 27.7%, and 38.6% of eyes in the 0.3 mg ranibizumab, 1.5 mg Faricimab, and 6 mg Faricimab groups, respectively.[55] DISCUSSION Conventional management of NPDR without DME included observation along with controlling the systemic condition. While approaches to the patients with PDR or DME is straightforward, the therapeutic approach to NPDR patients with no DME has not been well established. keywords: aflibercept; anti; complications; diabetes; diabetic; dme; eyes; intravitreal; npdr; patients; photocoagulation; progression; retinopathy; risk; study; treatment; vegf; vision cache: jovr-10175.pdf plain text: jovr-10175.txt item: #13 of 284 id: jovr-10176 author: Gonzalez Barlatay, J ; Pagano Boza, C ; Hernandez Gauna, GV ; Premoli, JE title: Orbital Inflammation Caused by Aminobisphosphonates date: 2022-01-21 words: 2888 flesch: 46 summary: Review Article Orbital Inflammation Caused by Aminobisphosphonates J Gonzalez Barlatay, MD; C Pagano Boza, MD; GV Hernandez Gauna, MD; JE Premoli, MD Division of Orbital and Ophthalmic Plastic Surgery, Hospital Italiano de Buenos Aires, Argentina ORCID: J Gonzalez Barlatay: http://orcid.org/0000-0002-3412-359X Abstract The aim of this review was to describe orbital inflammation secondary to aminobisphosphonates by analyzing demographic data, clinical presentation, and treatment of the disease. We found 43 cases of orbital inflammation due to aminobisphosphonates. keywords: acid; aminobisphosphonates; disease; inflammation; patients; treatment; zoledronate; zoledronic cache: jovr-10176.pdf plain text: jovr-10176.txt item: #14 of 284 id: jovr-10179 author: Behboudi, Hassan; Zayeni, Habib; Haji-Abbasi, Asghar ; Azaripour, Ebrahim; Alizadeh, Yousef; Soltani-Moghadam, Reza title: Coats’-like Response Associated with Linear Scleroderma date: 2022-01-21 words: 2060 flesch: 47 summary: Case Report Coats’-like Response Associated with Linear Scleroderma Hassan Behboudi1, MD; Habib Zayeni2, MD; Asghar Haji-Abbasi2, MD; Zahra Moravvej1, MD Ebrahim Azaripour1, MD; Yousef Alizadeh1, MD; Reza Soltani-Moghadam1, MD 1Eye Research Center, Department of Eye, Amiralmomenin Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran 2Rheumatology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran ORCID: Hassan Behboudi: https://orcid.org/0000-0001-9149-9270 Abstract Purpose: To present a case of linear scleroderma known as “en coup de sabre” associated with Coats’- like response. Intracranial vascular abnormalities have also been reported in patients with linear scleroderma. keywords: coats’-like; coup; linear; response; sabre; scleroderma cache: jovr-10179.pdf plain text: jovr-10179.txt item: #15 of 284 id: jovr-10180 author: Hassanpour, Kiana; Mohammadi, Negin; Sabbaghi, Hamideh; Pakravan, Mohammad title: Peripapillary Capillary Network in Methanol Induced Optic Neuropathy date: 2022-01-21 words: 2691 flesch: 46 summary: Moreover, the edema subsequent to RNFL damage may cause a compartment syndrome.[6] Various studies investigating OCT-A in different optic neuropathies reported a reduction of peripapillary vessel density, for example, in non-arteritic anterior ischemic optic neuropathy (NAION),[7] optic neuritis,[8] optic atrophy secondary to retinal dystrophies,[9] thyroid eye disease,[10] vitamin deficiency,[11] or Leber hereditary optic neuropathy (LHON).[12] Two possible mechanisms may explain peripapillary vessel density reduction in different optic neuropathies. Pakravan M, Sanjari N. Erythropoietin treatment for methanol optic neuropathy. keywords: density; methanol; mton; neuropathy; oct; optic; patient; peripapillary; vessel cache: jovr-10180.pdf plain text: jovr-10180.txt item: #16 of 284 id: jovr-10181 author: Bhattacharya, Shruti; Raina, Usha K; Gupta, Shantanu K; Mishra, Manisha; Saini, Varun; Kumar, Brajesh title: Tubercular Osteomyelitis of the Orbit Presenting as Periorbital Cellulitis date: 2022-01-21 words: 2357 flesch: 46 summary: Orbital TB can be diagnosed using the following criteria: (1) JOURNAL OF OPHTHALMIC AND VISION RESEARCH Volume 17, Issue 1, January-March 2021 147 Tubercular Orbital Osteomyelitis ; Bhattacharya et al clinical/radiological or histological evidence of TB from the orbital lesion associated with evidence of TB elsewhere, (2) demonstration of AFB in the orbital lesion, (3) isolation of mycobacteria in culture from biopsied tissue, and (4) demonstration of mycobacterial infection by doing a PCR on the biopsied tissue.[5] Orbital TB has been clinically classified into five categories: classical periostitis, orbital tuberculoma with no bony destruction, orbital TB with evidence of bony destruction (not classified as classical periostitis), orbital TB as a result of spread from paranasal sinuses and dacryoadenitis. However, uveal involvement is more common because of its high blood supply.[2, 3] Orbital TB is more commonly seen in children with a female predisposition. keywords: cellulitis; orbit; osteomyelitis; swelling; test; tuberculosis cache: jovr-10181.pdf plain text: jovr-10181.txt item: #17 of 284 id: jovr-10182 author: Commiskey, Patrick W; Kalra, Gagan; Chhablani, Jay title: Iatrogenic PVD Following Dilated Fundus Examination: A New Diagnosis or Fluke? date: 2022-01-21 words: 812 flesch: 44 summary: There is a known anatomical relationship between ciliary body contraction and anterior movement of anterior vitreous body and zonules.[2, 3] Anterior zonule movement results in adjacent anterior movement of the vitreous parallel to the sclera at the ora serrata.[4] While it is unclear if this force would translate to posterior vitreous movement, there is an interesting case report of vitreo-macular traction (VMT) following pilocarpine-induced miosis Axially, it is during the relaxation of accommodation that the posterior lens capsule moves anteriorly followed by subsequent anterior movement of posterior vitreous causing shearing at the retinal vitreous attachments.[6] keywords: accommodation; eye; pvd; vitreous cache: jovr-10182.pdf plain text: jovr-10182.txt item: #18 of 284 id: jovr-10183 author: Starr, Matthew R.; Bakri, Sophie J. title: Pigmentary Retinopathy and Chronic Subretinal Fluid Associated with Pseudoxanthoma Elasticum and Angioid Streaks date: 2022-01-21 words: 704 flesch: 45 summary: Following our patient for 10 years (5 years with spectral domain OCT), she has never had any evidence of a choroidal neovascular complex on fluorescein angiography and thus it was concluded that the subretinal fluid was the result of malfunctioning retinal pigment epithelium due to the pigmentary changes at the posterior pole, a rare finding first described by Zweifel and colleagues in 2011, who concluded the fluid was due to a similar pathophysiology as pattern dystrophy.[3] Clinicians should be aware of the ophthalmic manifestations of pseudoxanthoma elasticum which include angioid streaks which can lead to choroidal neovascularization and severe vision loss but also pigmentary changes at the posterior pole that can lead to chronic subretinal fluid and a milder effect on visual acuity. On OCT (C-F), there is evidence of bilateral subretinal fluid (red arrows) consistent with chronic RPE damage that are stable over five years (C & D images taken five years before E & F images). keywords: angioid; fluid; streaks cache: jovr-10183.pdf plain text: jovr-10183.txt item: #19 of 284 id: jovr-10184 author: Amigó, Alfredo; Martinez-Sorribes, Paula title: Toxic Intraocular Syndrome date: 2022-01-21 words: 917 flesch: 45 summary: Letter Toxic Intraocular Syndrome Alfredo Amigó, MD, PhD; Paula Martinez-Sorribes MS Instituto Oftalmológico Amigó, Santa Cruz de Tenerife, Spain J Ophthalmic Vis Res 2022; 17 (1): 155–156 Over the last three decades, several noninfectious postoperative inflammatory syndromes have been described: toxic anterior segment syndrome (TASS),[1] fibrin syndrome, sterile endophthalmitis, and toxic posterior segment syndrome (TPSS).[2, 3] All have a common toxic origin but none describe all the clinical forms in which toxicity can occur and there are cases of toxicity that do not fit into any of these syndromes. Andonegui J, Jimenez-Lasanta L, Aliseda D, Lameiro F. Outbreak of toxic anterior segment syndrome after vitreous surgery. keywords: segment; syndrome; tios; toxic cache: jovr-10184.pdf plain text: jovr-10184.txt item: #20 of 284 id: jovr-10185 author: Motevasseli, Tahmineh; Mohammadi, Saeed; Abdi, Fatemeh; Freeman, William R. title: Erratum to: Side Effects of Brolucizumab date: 2022-01-21 words: 95 flesch: 46 summary: Erratum Erratum: Side Effects of Brolucizumab J Ophthalmic Vis Res 2022; 17 (1): 157–157 In the article titled “Side Effects of Brolucizumab,” published on pages 670–675, Issue 4, Volume 16 of Journal of Ophthalmic and Vision Research,[1] the name of the second author is written incorrectly as “Saeed Mohammadi” instead of “S. Saeed Mohammadi.” J Ophthalmic Vis Res 2021;16:670–675. keywords: effects cache: jovr-10185.pdf plain text: jovr-10185.txt item: #21 of 284 id: jovr-10785 author: Nouri-Mahdavi, Kouros title: Editorial – An Alternate Technique for Goniotomy date: 2022-04-29 words: 988 flesch: 46 summary: Al Habash A, Albuainain A. Long term outcome of combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade in different subtypes of glaucoma. The average preoperative IOP was 17.4 (± 4.1) mmHg on 1.1 (± 1.4) topical glaucoma medications, which decreased to 13.3 (± 2.5 mmHg) at month six after the intervention; it must be noted that only 16 out of 22 eyes were receiving eye drops for IOP reduction before surgery. keywords: glaucoma; goniotomy; iop; trabeculotomy cache: jovr-10785.pdf plain text: jovr-10785.txt item: #22 of 284 id: jovr-10786 author: Dhiman, Richa; Lakshmipathy, Meena; Lakshmipathy, Dhanurekha; Lily, Therese K. title: Clinico-microbiological Profile of Nontuberculous Mycobacterial Keratitis date: 2022-04-29 words: 4716 flesch: 44 summary: Since 87.5% were speciated to M. abscessus in our study, we infer that the most effective agents against M. abscessus are AMK, CLR, and AZM which is in agreement to a study by Elliot et al.[19] Among fluoroquinolones, CIP and GAT were found to be resistant in 57.2% of M. abscessus isolates while MOX was resistant in 64.3% of M. abscessus isolates. Hence, based on our study sensitivity pattern, we suggest that topical AMK (2.5%) can be used either alone or in combination with oral CLR (500 mg) or AZM (500 mg) for NTM keratitis specifically for M. abscessus. keywords: abscessus; chelonae; keratitis; months; ntm; patients; pcr; study; success; total cache: jovr-10786.pdf plain text: jovr-10786.txt item: #23 of 284 id: jovr-10788 author: Ghaffari, Reza; Abdi, Parisa; Moghaddasi, Alireza; Heidarzadeh, Somayeh; Ghahvhechian, Hossein; Kasiri, Maryam title: Ray Tracing versus Thin-Lens Formulas for IOL Power Calculation Using Swept-Source Optical Coherence Tomography Biometry date: 2022-04-29 words: 5079 flesch: 49 summary: However, choosing the best method for IOL power calculation is still a challenging issue.[1, 2] Since 1999, with the introduction of IOL Master, optical biometry has established itself as the standard for axial length (AL) measurement. As a result, in order to design lenses and optical systems, the ray tracing method has now become the standard technique.[14] In this investigation, the OKULIX ray-tracing program was used to assess the accuracy of IOL power calculation, which combines corneal topography data for IOL power calculation, in comparison with the second- and third-generation formulas and the fourth-generation Haigis formula using an SS-OCT biometer (OA- 2000). keywords: error; formulas; iol; lens; okulix; power; prediction; ray; tracing cache: jovr-10788.pdf plain text: jovr-10788.txt item: #24 of 284 id: jovr-10789 author: Loukovaara, Sirpa; Haukka, JJari title: Association between NSAID and Statin Therapy and the Incidence of Intravitreal Anti-vascular Endothelial Growth Factor Injections and Nd:YAG Laser Treatment after Cataract Surgery in Finland date: 2022-04-29 words: 5326 flesch: 48 summary: Sirpa Loukovaara: https://orcid.org/0000-0002-2506-3900 Abstract Purpose: To examine the association between the use of topical non-steroidal anti- inflammatory (NSAID) medication, systemic statin therapy, and the incidence rate of two of the most common postsurgical procedures in adult patients undergoing cataract surgery in Finland between January 1, 2010 and December 31, 2016. In our registry cohort, patients with a prescription of topical NSAID (ketorolac) at the time of cataract surgery were less likely treated with intravitreal anti-VEGF injections after surgery (adjusted Poisson regression model IRR 0.3; 95% CI: 0.15–0.60, P = 0.0007), and also had reduced incidence of Nd:YAG laser (0.59, CI: 0.43–0.81, P = 0.0011) treatments. keywords: anti; cataract; incidence; intravitreal; laser; nsaid; statin; study; surgery; use; vegf; yag cache: jovr-10789.pdf plain text: jovr-10789.txt item: #25 of 284 id: jovr-10791 author: Ghasempour, Monireh; Khorrami-Nejad, Masoud ; Safvati, Aidin; Masoomian, Babak title: Interocular Axial Length Difference and Treatment Outcomes of Anisometropic Amblyopia date: 2022-04-29 words: 3655 flesch: 53 summary: The comparison of the pretreatment of corrected distance visual acuity (LogMAR) between children and adult groups, based on amblyopia treatment outcomes in anisometropic amblyopic patients. Comparison of the mean of the interocular axial length difference (mm) between the children and adult group based on amblyopia treatment outcomes. keywords: amblyopia; anisometropic; children; difference; group; mean; patients; treatment cache: jovr-10791.pdf plain text: jovr-10791.txt item: #26 of 284 id: jovr-10792 author: Asharlous, Amir; Doostdar, Asgar; Ghaemi, Vahid; Farzi, Mina; Yekta, Abbasali; Mortazavi, Abolghasem; Ostadimoghaddam, Hadi; Khabazkhoob, Mehdi title: Binocular Function in Different Gaze Positions date: 2022-04-29 words: 4599 flesch: 49 summary: This study compared multiple functions of binocular vision among different gaze positions. How to adjust angles and distances for measurements at different gaze positions. keywords: accommodation; amplitude; binocular; convergence; gaze; gaze positions; primary; study cache: jovr-10792.pdf plain text: jovr-10792.txt item: #27 of 284 id: jovr-10793 author: Chen, Ai-Hong; Muhamad, Nurulain title: Impact of Color and Polarity on Visual Resolution with Varying Contrast Ratios and Different Text Backgrounds date: 2022-04-29 words: 3922 flesch: 55 summary: Comparing color contrast and luminance contrast. Buchner A, Baumgartner N. Text – background polarity affects performance irrespective of ambient illumination and color contrast. keywords: acuity; background; color; contrast; luminance; polarity; ratio; resolution; study; text; vision; visual cache: jovr-10793.pdf plain text: jovr-10793.txt item: #28 of 284 id: jovr-10794 author: Eunice Amador Rosa, Mariel ; Lozano Bustillo, Alejandra ; Espinoza Salvadó, Iván ; Sierra, Manuel; Rivera, Belinda title: Prevalence and Causes of Avoidable Blindness in Subjects Over 50 Years of Age in Honduras date: 2022-04-29 words: 3933 flesch: 53 summary: These initiatives are already conditions outlined to achieve the basic global goal established by the WHO, which accounts for a 25% reduction in the prevalence of avoidable blindness and visual impairment by the year of 2020. National survey of avoidable blindness and visual impairment in Honduras. keywords: blindness; causes; honduras; impairment; prevalence; study; visual; years cache: jovr-10794.pdf plain text: jovr-10794.txt item: #29 of 284 id: jovr-10795 author: Kalantarion, Masomeh; Rajavi, Zhale; Sabbaghi, Hamideh; Kheiri, Bahareh; Hasan Shahriari, Mohammad ; Fatahi Mozafar, Farinaz title: Psychological Impact of COVID- 19 on the Ophthalmologists in Iran date: 2022-04-29 words: 4861 flesch: 44 summary: Depression in Regions with Different levels of Risk of Coronavirus Disease All ophthalmologists located in the low-risk regions had moderate depression and most of the JOURNAL OF OPHTHALMIC AND VISION RESEARCH Volume 17, Issue 2, April-June 2022 239 Psychological Impact of COVID- 19 on Ophthalmologists; Kalantarion et al participants (47.1%) located in the moderate-risk region had mild depression. An organized classification regarding the assessment of different depression severities identified as no (0–4), mild (5–9), moderate (10–14), or severe (15–21) was then considered for data analysis. keywords: coronavirus; covid-19; depression; health; impact; iran; ophthalmic; ophthalmologists; research; study; training cache: jovr-10795.pdf plain text: jovr-10795.txt item: #30 of 284 id: jovr-10796 author: Ghavidel, Leila Alizadeh; Bagheri, Masood; Mousavi, Farideh; Rezaei, Leila; Hazeri, Somayyeh; Hashemi, Hesam-Sadat title: Pattern and Visual Prognostic Factors of Behcet’s Uveitis in Northwest Iran date: 2022-04-29 words: 4897 flesch: 45 summary: Uvei�s Pan-Uvei�s Figure 2. Frequency of uveitis type in study patients at first (left chart) and last (right chart) ophthalmic visits. In addition, an epidemiologic study conducted over a period of 44 years from 1968 to 2011 by Accorinti et al demonstrated that the incidence of ocular BD is increasing in females.[17] keywords: eyes; follow; involvement; iran; ocular; patients; uveitis cache: jovr-10796.pdf plain text: jovr-10796.txt item: #31 of 284 id: jovr-10797 author: Hassanpour, Kiana; ElSheikh, Reem H.; Arabi, Amir; Frank, Charles R.; Elhusseiny, Abdelrahman M.; Eleiwa, Taher K.; Arami, Shiva; Djalilian, Ali R.; Kheirkhah, Ahmad title: Peripheral Ulcerative Keratitis: A Review date: 2022-04-29 words: 15482 flesch: 40 summary: In noninfectious PUK, local treatment is a cornerstone of symptom management and slowing the progression of corneal disease in PUK. Tear film MMP accumulation and corneal disease. keywords: agents; antibodies; april; arthritis; autoimmune; cases; cells; corneal; disease; et al; eye; hassanpour; immune; inflammation; inflammatory; issue; journal; june; keratitis; mooren; ocular; ophthalmol; ophthalmology; patients; perforation; peripheral; puk; research; rheumatoid; scleritis; severe; stromal; systemic; therapy; thinning; topical; treatment; ulcerative; ulcers; update; vasculitis; vision; volume cache: jovr-10797.pdf plain text: jovr-10797.txt item: #32 of 284 id: jovr-10804 author: Mehta, Neesurg S.; Emami-Naeini, Parisa title: A Review of Systemic Biologics and Local Immunosuppressive Medications in Uveitis date: 2022-04-29 words: 9684 flesch: 44 summary: Although rapid control of BD-related uveitis was noted in the pilot and phase-2 studies,[70, 71] the phase-3 EYEGUARD-B trial failed to meet its primary endpoint and the medicine did not significantly alter the risk of flares.[72] Anti-interleukin-2 Daclizumab Daclizumab (Zinbryta®) is a humanized monoclonal antibody that inactivates T lymphocytes by binding to the CD25 portion of the IL-2 receptor and is administered subcutaneously.[74] Nussenblatt et al. reported that patients with NIU treated with Daclizumab needed less concomitant immunosuppression while maintaining baseline vision at 26 weeks.[75] However, the medicine was withdrawn from the market in 2018 following cases of hepatic injury and meningoencephalitis.[76] Anti-IL-interleukin-6 Tocilizumab Tocilizumab (Actemra®) is a recombinant humanized monoclonal antibody against the IL-6 receptors and is most commonly administered subcutaneously (162 mg every two weeks).[79] An intravenous form is also available. 4. Kempen JH, Daniel E, Dunn JP, Foster CS, Gangaputra S, Hanish A, et al. keywords: adalimumab; anti; arthritis; behçet; disease; edema; efficacy; emami; et al; group; inflamm; inflammation; infliximab; intravitreal; macular; naeini; ophthalmol; patients; refractory; rheumatol; rituximab; safety; study; term; therapy; treatment; trial; uveitis; vision cache: jovr-10804.pdf plain text: jovr-10804.txt item: #33 of 284 id: jovr-10805 author: Gaur, Aman; Sarkar, Prathama title: Eye: The Hard-hit Victim of the COVID-19 Pandemic date: 2022-04-29 words: 3964 flesch: 51 summary: COVID-19 patients with an odds ratio of 3.4.[18] However, a systematic review which included 11 published articles analyzing 252 SARS-CoV- 2 patients infected globally reported a variable prevalence of conjunctivitis ranging between 0 and 32%, although no meta-analysis was performed. The Ct (cycle threshold) value for detection of SARS-CoV-2 in tear RT-PCR however showed a rising trend with progression in duration of illness, indicating a decrease in tear viral load.[15] The first case of hemorrhagic conjunctivitis with pseudo membrane in COVID-19 patient was reported from France, where ocular manifestations like conjunctival congestion and watery discharge were first noted at day 17 of systemic illness.[16] Direct microscopy/culture of conjunctival swabs and scrapings were done which ruled out any bacterial, chlamydial, and other viral etiology (like Herpes and adenovirus). keywords: computer; conjunctival; conjunctivitis; cov-2; covid-19; eye; eyes; health; pandemic; patients; sars; screen; use; vision cache: jovr-10805.pdf plain text: jovr-10805.txt item: #34 of 284 id: jovr-10809 author: Heshmati, Ali; Taghizadeh, Peyman; Ahmadieh, Hamid; Yaseri, Mehdi; Suri, Fatemeh; Alizadeh, Mahsa; Dadashzadeh, Marjan; Khatami, Hajar; Moradkhah Navi, Monireh ; Zamanparvar, Parisa; Behboudi, Hassan; Elahi, Elahe title: Erratum – Carrier Status for p.Gly61Glu and p.Arg368His CYP1B1 Mutations Causing Primary Congenital Glaucoma in Iran date: 2022-04-29 words: 355 flesch: 48 summary: No. individuals screened No. mutation carriers Frequency of carriers* 95% Confidence interval of mutation carriers Total 1036 9 0.86% 0.45% - 1.64% Urban 584 5 0.85% 0.37% - 1.99% Rural 452 4 0.88% 0.34% - 2.25% *The difference in frequency of carriers in urban and rural regions was not statistically significant. No. individuals screened No. mutation carriers Frequency of carriers* 95% Confidence interval of mutation carriers All of east of Total 3029 73 2.41% 1.91% - 3.04% Gilan Urban 2160 51 2.36% 1.08% - 3.09% Rural 869 22 2.53% 1.68% - 3.8% Bandar Anzali Total 389 11 2.82% 1.57% - 4.99% Urban 336 8 2.38% 1.21% - 4.63% Rural 53 3 5.66% 1.94% - 15.37% Lahijan Total 376 5 1.32% 0.58% - 3.15% Urban 226 4 1.77% 0.69% - 4.46% Rural 150 1 0.67% 0.12% - 3.68% Rasht Total 2095 54 2.58% 1.98% - 3.35% Urban 1481 37 2.50% 1.82% - 3.42% Rural 614 17 2.77% 1.74% - 4.39% Astaneh Ashrafieh Total 169 3 1.78% 0.61% - 5.09% Urban 117 2 1.71% 0.47% - 6.02% Rural 52 1 1.92% 0.34% - 10.12% *Differences in frequencies among the cities and between the urban and rural regions of each of the cities were not statistically significant. keywords: carriers cache: jovr-10809.pdf plain text: jovr-10809.txt item: #35 of 284 id: jovr-10825 author: Manafi, Navid; Abri Aghdam, Kaveh title: Letter – Authors’ Reply date: 2022-04-29 words: 1096 flesch: 49 summary: J Ophthalmic Vis Res 2021;16:77–83. 5. Dinkin M, Johnson E. One giant step for giant cell arteritis: Updates in diagnosis and treatment. We found that the majority of temporal artery biopsies (TABs) led to negative results and giant cell arteritis (GCA) could be diagnosed based on clinical grounds rather than relying just on TAB. keywords: arteritis; cell; diagnosis; tab cache: jovr-10825.pdf plain text: jovr-10825.txt item: #36 of 284 id: jovr-10826 author: Delrish, Elham; Ghassemi, Fariba; Jabbarvand, Mahmoud; Lashay, Alireza; Atyabi, Fatemeh; Soleimani, Masoud; Dinarvand, Rassoul title: Erratum – Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma date: 2022-04-29 words: 232 flesch: 43 summary: Delrish E, Ghassemi F, Jabbarvand M, Lashay A, Atyabi F, Soleimani M, et al. J Ophthalmic Vis Res 2022;17:58–68. keywords: phd cache: jovr-10826.pdf plain text: jovr-10826.txt item: #37 of 284 id: jovr-11567 author: Banaee, Touka title: Editorial – Optical Coherence Tomography Angiography: Considerations Regarding Diagnostic Parameters date: 2022-08-09 words: 2219 flesch: 48 summary: Changes in retinal blood flow in response to an experimental increase in IOP in healthy participants as assessed with doppler optical coherence tomography. Also, the degree of blood pressure rise may differ based on age and presence of diabetes. keywords: acute; blood; changes; flow; iop; octa; pressure cache: jovr-11567.pdf plain text: jovr-11567.txt item: #38 of 284 id: jovr-11568 author: Franco, Fabrizio; Branchetti, Marco; Vicchio, Lidia; Serino, Federica; Piergentili, Marco; Spagnuolo, Vito; Santoro, Francesca; Virgili, Gianni; Giansanti, Fabrizio title: Implantation of a Small Aperture Intraocular Lens in Eyes with Irregular Corneas and Higher Order Aberrations date: 2022-08-09 words: 3581 flesch: 52 summary: Visual acuity study. Small aperture IOL specifications: optic and mask design (right). keywords: aperture; cataract; corneal; hoas; ic-8; iol; lens; patients; study cache: jovr-11568.pdf plain text: jovr-11568.txt item: #39 of 284 id: jovr-11569 author: Mohamadmehdi Moshtaghion, Seyed ; Abolhosseini, Mohammad; Kheiri, Bahareh; Ali Javadi, Mohammad ; Ziaee Ardakani, Leila ; Rezaei Kanavi, Mozhgan title: Eye Bank Records on Pediatric Keratoplasty date: 2022-08-09 words: 7561 flesch: 60 summary: 8/ 8/ N /S (15 .7 % /8 % ) 29 (5 6. 9% ) 5 (9 .8 % ) N /S 51 (10 0 % ) % ) 30 (19 .2 % ) keywords: 0.001; age; bank; corneal; eye; eyes; group; indications; iran; keratoconus; keratoplasty; trend; years cache: jovr-11569.pdf plain text: jovr-11569.txt item: #40 of 284 id: jovr-11570 author: Mirzaie, Mohammad; Bahremani, Erfan; Taheri, Nazli; Khamnian, Zhila; Kharrazi Ghadim, Banafshe title: Cataract Grading in Pure Senile Cataracts: Pentacam versus LOCS III date: 2022-08-09 words: 4238 flesch: 52 summary: They reported their results following a variety of variables they studied and found a positive linear correlation between LOCS III grading and the peak value of lens density measured using Pentacam in pure nuclear cataract patients. PNS Grading Score based on LOCS Ill classification. LOCS III PNS Grading Frequency Percentage (%) Median (PNS Grading Score) keywords: age; cataract; correlation; grading; iii; lens; locs; patients; pentacam; pns; system cache: jovr-11570.pdf plain text: jovr-11570.txt item: #41 of 284 id: jovr-11571 author: Jiang, Cynthia; Hodson, Noah; Johnson, Daniel; Kheirkhah, Ahmad title: Accuracy of IOL Power Calculation Formulas for AcrySof SN60WF versus Tecnis ZCB00 Intraocular Lenses date: 2022-08-09 words: 5977 flesch: 58 summary: To evaluate the possible effects of the IOL type on the accuracy of IOL power formulas, in this study we compared this accuracy for two different models of IOL. For ZCB00 lenses, however, this benchmark was met for all formulas only for short and medium eyes, but not for any formula in long eyes, showing the effects of IOL model on the accuracy of IOL power formulas. keywords: accuracy; eyes; formulas; iol; lenses; mae; power; sn60wf; zcb00; ±0.5 cache: jovr-11571.pdf plain text: jovr-11571.txt item: #42 of 284 id: jovr-11572 author: Barzanouni, Ehsan; Idani, Diba; Sharifipour, Farideh title: In Vivo Intraocular Lens Thickness Measurement and Power Estimation Using Optical Coherence Tomography date: 2022-08-09 words: 2866 flesch: 51 summary: IOL thickness correlated significantly with labelled IOL power (R2 = 0.985, P < 0.001). Plot of IOL thickness (microns) against labelled IOL power (D). keywords: iol; lens; measurements; oct; power; thickness cache: jovr-11572.pdf plain text: jovr-11572.txt item: #43 of 284 id: jovr-11573 author: Ashraf Khorasani, Maryam ; Garcia, Giancarlo; Anvari, Pasha; Habibi, Abbas; Ghasemizadeh, Shahriar; Ghasemi Falavarjani, Khalil title: Optical Coherence Tomography Angiography Findings after Acute Intraocular Pressure Elevation in Patients with Diabetes Mellitus versus Healthy Subjects date: 2022-08-09 words: 4940 flesch: 52 summary: Higher levels of IOP changes may affect the microvascular network differently. In addition, LPI might have adversely affected the image quality and therefore subsequent vessel density measurements.[35] Wen et al[36] investigated optic disc perfusion immediately after the administration of intravitreal anti-VEGF injections and found a significant reduction in optic disc vessel density. keywords: acute; changes; dcp; density; disc; elevation; eyes; glaucoma; iop; vessel; vessel density cache: jovr-11573.pdf plain text: jovr-11573.txt item: #44 of 284 id: jovr-11574 author: Kim, Diana; Bautista, Sana; Meer, Elana; McGeehan, Brendan; Maguire, Maureen; Briceño, César title: Changes in Intraocular Pressure with Use of Periocular Triamcinolone Cream date: 2022-08-09 words: 4219 flesch: 54 summary: Conclusion: In patients taking periocular triamcinolone cream, there was no clinically meaningful change in mean IOP between baseline and follow-up visits, and IOP measurements were not related to variances in prescription strength or duration of therapy. Demographic data including age, sex, triamcinolone dose, IOP measurements, method of measurements, and time of measurements were recorded for baseline (pretreatment) and at follow-up visits for those patients who remained This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. keywords: baseline; follow; iop; patients; topical; triamcinolone; use; visit cache: jovr-11574.pdf plain text: jovr-11574.txt item: #45 of 284 id: jovr-11575 author: Karimi, Saeed; Parvizi, Farhad; Arabi, Amir; Shahraki, Toktam; Safi, Sare title: Oral Vitamin D Supplementation and Clinical Outcomes of Intravitreal Bevacizumab Injection for Macular Edema Secondary to Retinal Vein Occlusions date: 2022-08-09 words: 4030 flesch: 51 summary: The correlation between vitamin D levels, BCVA and CMT. Baseline BCVA in BRVO eyes Baseline BCVA in CRVO eyes Baseline CMT in BRVO eyes Baseline CMT in CRVO eyes Vitamin D serum level Pearson’s correlation –0.042 0.083 0.101 –0.022 P-value 0.715 0.685 0.541 0.741 BCVA, best-corrected visual acuity; CMT, central retinal thickness; CRVO, central retinal vein occlusion; BRVO, branch retinal vein occlusion. Macular edema and macular ischemia are the main causes of visual impairment in RVO, which are more frequent and less responsive to treatment in CRVO.[1] Vitamin D is a nutritional supplement which plays an important role in various pathways in the body through the presence of its receptor in several tissues, including the bones, vascular myocytes, cardiac cells, hepatocytes, and immune cells. keywords: bcva; brvo; cmt; crvo; ivb; patients; retinal; vitamin cache: jovr-11575.pdf plain text: jovr-11575.txt item: #46 of 284 id: jovr-11576 author: Farvardin, Majid; Kalantari, Zahra; Talebnejad, Mohammadreza; Norouzpour, Amir title: Long-term Visual and Refractive Outcomes of Argon Laser-treated Retinopathy of Prematurity date: 2022-08-09 words: 4074 flesch: 56 summary: Long term visual outcomes in laser treated threshold retinopathy of prematurity in Central Saudi Arabia. Unilateral myopia resulted in anisometropia in treated cases in the current study. keywords: argon; cases; eyes; group; laser; rop cache: jovr-11576.pdf plain text: jovr-11576.txt item: #47 of 284 id: jovr-11577 author: Esposti, Giulia; Luigi Esposti, Pier ; Costantino, Francesco; Zappalà, Dario; Pinna, Antonio; Fruschelli, Mario title: Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery date: 2022-08-09 words: 3846 flesch: 52 summary: Dorin G. Evolution of retinal laser therapy: Minimum intensity photocoagulation (MIP). Photostimulation reactivates RPE cellular activity,[19, 20] with up- and downregulation of various RPE factors stimulating fluid resorption,[21, 22] such as overexpression of stromal cell-derived factor 1 (SDF1), which attracts stem cells and restores the normal function of RPE by renewing dead epithelial and endothelial cells.[23, 24] Photothermal stimulation induces the expression of heat shock protein (HSP), which normalizes the levels of cytokines and reduces chronic inflammation.[19] PSF after retinal surgery for RRD is a relatively uncommon and self-limiting condition, which can occasionally cause major visual loss. keywords: detachment; fluid; laser; micropulse; ophthalmol; photostimulation; rrd; surgery cache: jovr-11577.pdf plain text: jovr-11577.txt item: #48 of 284 id: jovr-11578 author: Salehi Fadardi, Marzieh ; Salehi Fadardi, Javad ; Mahjoob, Monireh; Doosti, Hassan title: Post-saccadic Eye Movement Indices Under Cognitive Load: A Path Analysis to Determine Visual Performance date: 2022-08-09 words: 4720 flesch: 45 summary: During the next step, path analysis (standardized regression coefficients and correlation between variables) was used to develop a model to assess how the changes in load indicators affected visual task performance through possible alterations in saccades and/or fixation eye movements. Despite changes in the occurrence of secondary saccades with the high load, we did not find any effect of secondary saccades on visual task performance. keywords: changes; eye; fixation; latency; load; participants; performance; saccade; target; task; time; visual cache: jovr-11578.pdf plain text: jovr-11578.txt item: #49 of 284 id: jovr-11580 author: Rezaei, Leila; Hawasi, Ehsan; Salari, Nader; Mohammadi, Masoud title: Prevalence of Color Blindness in Iranian Students: A Meta-analysis date: 2022-08-09 words: 4445 flesch: 57 summary: This study aims to examine the prevalence of color blindness in Iranian students through a meta-analysis. Articles related to color blindness published between January 1990 and December 2020 were searched in Scopus, Cochrane Library, Web of Science (WoS), Science Direct, Embase, SID, MagIran, IranDoc, Medline, and Google Scholar databases. keywords: blindness; color; color blindness; figure; prevalence; red; research; students; studies; study; vision cache: jovr-11580.pdf plain text: jovr-11580.txt item: #50 of 284 id: jovr-11582 author: Pakdel, Farzad; Zand, Amin; Sharifi, Ali; Asadi, Masih; Abri Aghdam, Kaveh title: Challenges and Pitfalls in the Management of Rhino-Orbital Mucormycosis in Ophthalmology: A Highlighted Problem in the COVID-19 Era date: 2022-08-09 words: 5196 flesch: 36 summary: When Is the Retrobulbar Injection of Amphotericin B Indicated? Retrobulbar injection of amphotericin B may facilitate improvement of orbital mucormycosis, in combination with systemic antifungal drugs, and reduce the rate of aggressive interventions including orbital tissues debridement or exenteration. Retrobulbar Injection of amphotericin B for orbital mucormycosis. keywords: administration; amphotericin; cases; challenges; covid-19; disease; drug; exenteration; management; mucormycosis; ophthalmology; orbital; patients; rhino; treatment cache: jovr-11582.pdf plain text: jovr-11582.txt item: #51 of 284 id: jovr-11585 author: Abri Aghdam, Kaveh ; Aghajani, Ali; Khakpour, Mehdi; Soltan Sanjari, Mostafa title: Bilateral Anterior Ischemic Optic Neuropathy Accompanied with Unilateral Central Retinal Artery Occlusion in a Biopsy-proven Case of Giant Cell Arteritis date: 2022-08-09 words: 1180 flesch: 43 summary: The patient was admitted and pulse corticosteroid therapy was commenced with the diagnosis of giant cell arteritis (GCA). The overall findings are compatible with the diagnosis of giant cell arteritis (hematoxylin and eosin staining, 40X magnification) (C). keywords: cell; eye; filling; optic; vision cache: jovr-11585.pdf plain text: jovr-11585.txt item: #52 of 284 id: jovr-11586 author: Saber Sahih Alnasab, Seyed ; Asharlous, Amir; Doostdar, Asgar; Nabovati, Payam; Yekta, Abbasali; Khabazkhoob, Mehdi title: Epidemiology of Dry Eye and Its Determinants Among University Students date: 2022-08-09 words: 1084 flesch: 47 summary: Letter Epidemiology of Dry Eye and Its Determinants Among University Students Seyed Saber Sahih Alnasab1, MS; Amir Asharlous2, PhD; Asgar Doostdar2, MS; Payam Nabovati2, PhD, Abbasali Yekta3, PhD, MS; Mehdi Khabazkhoob4, PhD 1Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran 2Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran 3Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran 4Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran ORCID: Seyed Saber Sahih Alnasab: https://orcid.org/0000-0001-5068-7371 J Ophthalmic Vis Res 2022; 17 (3): 447–448 Dear Editor, Dry eye syndrome (DES) is defined as a multifactorial disease of the tears and ocular surface which is associated with symptoms of discomfort and visual disturbance, with potential damage to the ocular surface.[1] Dry eye may cause several ocular and visual symptoms (including stinging or burning, excessive tearing, gritty sensation, episodes of blurred vision, and redness) negatively impacting the quality of life due to its extensive ocular consequences.[1] About 60% of the patients complain about decreased quality of life in their daily and leisurely activities.[2] University students comprise a young population that spends a significant amount of time on reading and working with the computer. The prevalence of DES was higher in Iranian students compared to other similar studies, which could be due to geographical, lifestyle, climatic, and even ethnic differences.[3] While some studies[4,5] reported a direct correlation between the prevalence of dry eye and age, this study found no significant relationship between DES prevalence and age, which could be due to the limited age range of the subjects. keywords: des; eye; prevalence; sciences; university cache: jovr-11586.pdf plain text: jovr-11586.txt item: #53 of 284 id: jovr-12294 author: Sheibani, Nader title: Editorial – Connective Tissue Growth Factor: A Key Factor Among Mediators of Tissue Fibrosis date: 2022-11-24 words: 2834 flesch: 49 summary: Connective tissue growth factor as a mediator of intraocular fibrosis. Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork. keywords: cells; ctgf; factor; fibrosis; growth; growth factor; ophthalmol; tissue; tissue growth cache: jovr-12294.pdf plain text: jovr-12294.txt item: #54 of 284 id: jovr-12296 author: Kuzman, Tomislav; Meter, Ana; Kalauz, Miro; Masnec, Sanja; Škegro, Ivan; Jonjić, Ivana title: Influence of Donor Thickness on Visual Acuity in Descemet’s Stripping Automated Endothelial Keratoplasty date: 2022-11-24 words: 5108 flesch: 50 summary: Tourabaly et al in recent papers suggest that there were no significant differences in final visual acuity regardless of lamellar thickness from 15 to 250 μm.[20] It can be concluded that there are studies that confirm our research, while those that reflect the opposite are usually comparing preoperative lamella thickness with postoperative visual acuity. Patients had no other comorbidities that could affect visual acuity. keywords: acuity; cornea; descemet; donor; dsaek; endothelial; keratoplasty; lamella; postoperative; stripping; study; thickness; visual cache: jovr-12296.pdf plain text: jovr-12296.txt item: #55 of 284 id: jovr-12298 author: Ahmadpour, Farnaz; Nahidi, Yalda; Daneshvar, Ramin title: Dermatological Findings in Glaucoma Patients: Comparison Between Pseudoexfoliative and Primary Open-angle Glaucoma date: 2022-11-24 words: 4158 flesch: 47 summary: For example, twice higher frequency of dry skin in PEXG patients than in POAG patients did not reach statistical significance; on the other hand, although PEXG patients were almost a decade older than POAG patients, we did not find any effect of age on the frequency of skin manifestations. Conclusion: Integumentary system disorders are pervasive in glaucoma patients, and dermatologic evaluation in glaucoma patients should be considered for diagnostic and therapeutic purposes. keywords: dermatitis; eye; glaucoma; manifestations; patients; pexg; poag; pseudoexfoliation; seborrheic; skin; study; syndrome cache: jovr-12298.pdf plain text: jovr-12298.txt item: #56 of 284 id: jovr-12303 author: Shah, Dhruven; Dhamankar, Rita; Shetty, Vijay; Haldipurkar, Suhas; Chipade, Prakash; Tanwar, Shabnam; Sankhe, Prachi; Venkatramani, Devendra; Mhatre, Paresh; Setia, Maninder Singh title: Individual and Combined Effects of Diabetes and Glaucoma on Total Macular Thickness and Ganglion Cell Complex Thickness: A Cross-sectional Analysis date: 2022-11-24 words: 6523 flesch: 57 summary: Correlation among retinal thickness, optic disc, and visual field in glaucoma patients and suspects: A pilot study. Presence of diabetes in glaucoma patients may influence findings while documenting the progression of glaucoma. keywords: diabetes; diabetes group; diabetic; gcc; glaucoma; glaucoma group; group; macular; parameters; patients; rnfl; study; thickness; values; volume cache: jovr-12303.pdf plain text: jovr-12303.txt item: #57 of 284 id: jovr-12306 author: Hashemi, Hassan; Nabovati, Payam; Yekta, Abbasali; Borojerdi, Ali; Fallahkohan, Hamidreza; Rezvan, Farhad; Khabazkhoob, Mehdi title: Abnormal Visual Function: An Under-recognized Risk Factor of Road Traffic Injuries date: 2022-11-24 words: 4448 flesch: 55 summary: Original Article Abnormal Visual Function: An Under-recognized Risk Factor of Road Traffic Injuries Hassan Hashemi1, MD; Payam Nabovati2, PhD; Abbasali Yekta3, PhD; Ali Borojerdi4, MS; Hamidreza Fallahkohan4, MS; Farhad Rezvan5, MD; Mehdi Khabazkhoob6, PhD 1Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran 2Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran 3Department of Optometry, Mashhad University of Medical Sciences, Mashhad, Iran 4Budget and Planning Office of Road Maintenance and Transportation Organization, Tehran, Iran 5Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran 6Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran ORCID: Hassan Hashemi: https://orcid.org/0000-0002-6086-1537 Abstract Purpose: To determine the relationship between road accidents with visual acuity, refractive errors, visual field, and contrast sensitivity. Moreover, 16.2% of the cases and 8.3% of the controls had visual field defects in both eyes (cOR = 2.13, 95% CI: 1.17–3.86; P =. 0.012); this significant relationship was still observed after adjusting for the effects of age and visual acuity (aOR = 1.90, 95% CI: 1.04– 3.49; P = 0.037). keywords: accidents; case; contrast; control; group; risk; road; sensitivity; study; visual cache: jovr-12306.pdf plain text: jovr-12306.txt item: #58 of 284 id: jovr-12314 author: Perumal, Selvamani; Venkatramanan, Surya; RJ, Venkatramanan; T, Jayanthi; Adithya, Jai; Abraham, Anjaly; Cheria, Henna title: Clinical Evaluation of the 3nethra Aberro Handheld Autorefractometer date: 2022-11-24 words: 2934 flesch: 54 summary: Agreement of the AHAR with SR power vector errors in both eyes. Agreement of the AHAR with SR errors in both eyes (compound representation). keywords: aberro; agreement; ahar; autorefractometer; errors; eye; eyes; measurements cache: jovr-12314.pdf plain text: jovr-12314.txt item: #59 of 284 id: jovr-12315 author: Sabbaghi, Hamideh; Kalantarion, Masomeh; Yaseri, Mehdi; Kheiri, Bahareh; Rajavi, Zhale; Safi, Sare title: Job Satisfaction among Ophthalmologists in Iran date: 2022-11-24 words: 4150 flesch: 47 summary: Our literature review shows that although most studies investigated job satisfaction among medical professionals, especially nurses,[25–27] few studies focused on ophthalmologists.[28, 29] In this regard, the discoveries of a study conducted by Nair et al to investigate the job satisfaction among Indian ophthalmologists can be used for comparison with the study on Iranian ophthalmologists.[28] Overall, the present study showed an acceptable level of job satisfaction (63.5%) among Iranian ophthalmologists, which is consistent with the results reported among Indian and Nigerian ophthalmologists with job satisfaction levels of 54.21% and 78.5%, respectively.[28, 29] Highest job satisfaction levels were positively related to the following factors: freedom to choose how to work (98.3%); variety of work (93.2%); level of responsibility (88.1%); and feelings of satisfaction (88.1%). keywords: iran; job; job satisfaction; levels; medical; ophthalmologists; questionnaire; research; satisfaction; study; tehran; work cache: jovr-12315.pdf plain text: jovr-12315.txt item: #60 of 284 id: jovr-12325 author: Zartasht Khan, Ayyad ; Utheim, Tor Paaske; Eidet, Jon Roger title: Retinal Pigment Epithelium Transplantation: Past, Present, and Future date: 2022-11-24 words: 3554 flesch: 42 summary: The first proof-of-concept study of RPE transplantation was performed in 1984 by Gouras et al in monkeys.[11] Four years later, Li and Turner published a report demonstrating that subretinal injection of RPE cells prevented photoreceptor degeneration in rats.[12] The field has subsequently matured at a rapid pace with not only animal studies,[13–15] but also human trials, using RPE of fetal,[16, 17] post-mortem adult,[18–20] autologous,[21–23] induced pluripotent stem cell (iPSC)-derived[24] and embryonic stem cell (ESC)-derived origin.[25–27] The introduction of IPSC- and ESC-derived RPE have been critical for the advancement of clinical RPE research during the recent years, and has, to a large extent, solved the issue of sourcing RPE donor tissue. RPE cells can easily be visualized in vivo, sustainable in vitro, and differentiated from stem cells with a relatively straightforward protocol. keywords: age; cell; degeneration; epithelium; human; ophthalmol; patients; phase; pigment; retinal; rpe; stem; study; transplantation cache: jovr-12325.pdf plain text: jovr-12325.txt item: #61 of 284 id: jovr-12342 author: Dada, Tanuj; Shakrawal, Jyoti; Ramesh, Priyanka; Sethi, Anin title: Trabeculectomy Augmented with Limited Deep Sclerectomy and Cyclodialysis with Use of Scleral Tissue as a Spacer date: 2022-11-24 words: 2342 flesch: 45 summary: Dev Ophthalmol 2017;59:36–42. 4. Cantor LB, Mantravadi A, WuDunn D, Swamynathan K, Cortes A. Morphologic classification of filtering blebs after glaucoma filtration surgery: The Indiana Bleb Appearance Grading Scale. Considering the higher failure rate of conventional trabeculectomy with mitomycin-C (MMC) in post VR surgery glaucoma, presence of 360 encircling band, and non-affordability precluding the use of glaucoma drainage devices, we planned to augment the conventional trabeculectomy surgery with deep sclerectomy and cyclodialysis. keywords: cleft; cyclodialysis; deep; glaucoma; sclerectomy; surgery; trabeculectomy cache: jovr-12342.pdf plain text: jovr-12342.txt item: #62 of 284 id: jovr-12343 author: Fleischman, David; Killer, Hanspeter title: Unvalidated Cerebrospinal Fluid Pressure Equations Should Not Be Used For Research date: 2022-11-24 words: 546 flesch: 39 summary: Letter Unvalidated Cerebrospinal Fluid Pressure Equations Should not Be Used for Research David Fleischman1, MD; Hanspeter E. Killer2, MD 1Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 2Kantonsspital Aarau, Department of Ophthalmology, Aarau, Switzerland ORCID: David Fleischman: https://orcid.org/0000-0002-1043-2021 J Ophthalmic Vis Res 2022; 17 (4): 601–602 Dear Editor, We have found an unsettling trend of articles being published with the use of an unvalidated formula for estimating cerebrospinal fluid pressure. Flawed approximation of CSF pressure is in no way helpful in advancing the science in glaucoma research. keywords: fluid; pressure cache: jovr-12343.pdf plain text: jovr-12343.txt item: #63 of 284 id: jovr-12344 author: Cruz, Natasha; Santos, Katia; Matuoka, Mateus; Kasahara, Niro title: Authors' Reply to Unvalidated Cerebrospinal Fluid Pressure Equations Should Not Be Used For Research date: 2022-11-24 words: 973 flesch: 60 summary: E-mail: niro.kasahara@fcmsantacasasp.edu.br Received: 23-08-2022 Accepted: 07-09-2022 Access this article online Website: https://knepublishing.com/index.php/JOVR DOI: 10.18502/jovr.v17i4.12344 Performing a multivariate analysis in the training group with the lumbar CSFP measurements as dependent variable and age, BMI and blood pressure as independent variables revealed that estimated CSFP was best described by the formula of Estimated CSFP The authors included 72 neurology patients who underwent CSFP measurement by lumbar puncture and 3.0-Tesla orbital magnetic resonance imaging for different clinical reasons. keywords: csfp; pressure cache: jovr-12344.pdf plain text: jovr-12344.txt item: #64 of 284 id: jovr-12345 author: Dehghan, Mahmoud; Nourinia, Ramin; Fekri, Sahba; Abtahi, Seyed-Hossein title: Torpedo Retinopathy or Chorioretinopathy? date: 2022-11-24 words: 682 flesch: 43 summary: Letter Torpedo Retinopathy or Chorioretinopathy? Mahmoud Dehghan1,2, MD; Ramin Nourinia1,2, MD; Sahba Fekri1,2, MD; Seyed-Hossein Abtahi1,2, MD 1Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2Department of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ORCID: Mahmoud Dehghan: https://orcid.org/0000-0001-5102-1109 Seyed-Hossein Abtahi: https://orcid.org/0000-0002-1459-6752 J Ophthalmic Vis Res 2022; 17 (4): 605–606 Dear Editor, We read with great interest the recent case series by Venkatesh and colleagues about the spectrum and features of Torpedo lesions described in nine subjects.[1] As far as we are aware, the Journal of Ophthalmic and Vision Research has recently published another report on the same topic,[2] and we have encountered such rare cases in our daily practice at Labbafinejad Medical Center as one of the main tertiary centers for retinal diseases. Herein, we would like to draw the kind attention of readers toward some pathophysiologic issues about the origin of Torpedo lesions. keywords: lesions; ophthalmic; torpedo cache: jovr-12345.pdf plain text: jovr-12345.txt item: #65 of 284 id: jovr-12346 author: Venkatesh, Ramesh; Jain, Kushagra; Pereira, Arpitha; Thirumalesh, MB; Yadav, Naresh Kumar title: Authors' Reply to Torpedo Retinopathy or Chorioretinopathy? date: 2022-11-24 words: 524 flesch: 50 summary: J Ophthalmic Vis Res 2020;15:187– 194. Ramesh Venkatesh: https://orcid.org/0000-0002-4479-9390 J Ophthalmic Vis Res 2022; 17 (4): 607–607 Dear Editor, We thank the author for showing interest in our article titled “Torpedo Retinopathy” and for providing important comments on it.[1] keywords: torpedo; venkatesh cache: jovr-12346.pdf plain text: jovr-12346.txt item: #66 of 284 id: jovr-12349 author: Juliane, Mehlan; Anne-Isabel, Lehman ; Myriam, Cichocki; Vasyl, Druchkiv; Toam, Katz; Linke, Stephan title: Biometry and Intraocular Lens Power Calculation by Combined Scheimpflug-Placido Disc versus Optical Interferometry Devices date: 2022-11-24 words: 4662 flesch: 50 summary: A widespread device for IOL power calculation is IOL Master 500 (Zeiss, Germany) which uses partial coherence interferometry for the axial length and lens thickness and placido and Scheimpflug technology for the k values and calculates the IOL-power using the established formulas such as Haigis, SRK/T, etc. All of these differences (between Galileo and IOL Master measurements) were statistically significant (P < 0.001). keywords: calculation; difference; galilei; galilei g6; iol; iol master; refraction cache: jovr-12349.pdf plain text: jovr-12349.txt item: #67 of 284 id: jovr-12350 author: Pakravan, Mohammad; Samaeili, Azadeh; Esfandiari, Hamed; Hassanpour, Kiana; Hooshmandi, Sadid; Yazdani, Shahin; Sharifipour, Farideh; Doozandeh, Azadeh; Einollahi, Bahram; Pakravan, Parastou; Shahriari, Mohammad Hasan; Kheiri, Bahareh title: Influence of Near Vision Tasks on Intraocular Pressure in Normal Subjects and Glaucoma Patients date: 2022-11-24 words: 4501 flesch: 55 summary: The mean baseline IOP ± SD was 14.43 ± 3.96, 14.11 ± 3.99, 13.62 ± 4.57, and 14.27 ± 3.98 mmHg in groups 1 to 4, respectively (P = 0.807). This study aims to investigate the magnitude of IOP changes induced by continuous or static accommodation during near vision work in glaucomatous and normal eyes. keywords: accommodation; angle; eyes; glaucoma; groups; intraocular; iop; min; pressure; reduction; study; vision cache: jovr-12350.pdf plain text: jovr-12350.txt item: #68 of 284 id: jovr-12415 author: Editorial Board, JOVR title: Acknowledgement to Reviewers 2022 date: 2022-11-29 words: 392 flesch: 11 summary: Abolfazl Karimiyan Mansooreh Jamshidian Abouzar Bagheri Mantapond Ittarat Abrishami Mojtaba Maryam Aletaha Acieh Es'haghi Maryam Yadgari Afagh Alavi Masomeh Kalantarion Afshin Lotfi-Sedigh Masood Naseripour Ahad Sedaghat Masoud Mirghorbani Ahmad Kheirkhah Masoumeh Masoompour Aidin Meshksar Mehdi Khabbazkhoob Aliakbar Sabermoghaddam Ranjbar Mehdi Moddareszadeh Alireza Esmaeili Mehdi Mazloumi Alireza Hedayatfar Mehran Zarei-Ghanavati Alireza Khodabandeh Mehrdad Mohammadpour Alireza Peyman Mehrnaz Atighehchian Alireza Ramezani Mehrnaz Geranmayeh Amir Faramarzi Mohadeseh Feizi Amir Norouzpour Mohammad Soleimani Amir Azharlous Mohammad Banifatemi Amirreza Veisi Mohammad Hasan Alemzadeh-Ansari Arash Mirmohammadsadeghi Mohammad Hossein Nowroozzadeh Arezoo Miraftabi Mohammad Reza Niyousha Arezoo Miraftabi Mohammad Reza Peyman Asieh Heirani-Tabasi Mohammad Taher Rajabi Azadeh Doozandeh Mohammad-Nasser Hashemian Bagher Hoseini Mohammad-Reza Sedaghat Bahareh Kheiri Mohammadmehdi Hatami Bahman Zeynali Mohammadreza Akbari-Baghbani Bahram Eshraghi Mohammadreza Jafarinasab Batoul Mousavi Mohsen Azarmina Behzad Fallahi-Motlagh Mojdeh Mohseni Microsoft Word - JOVR – ready.docx © keywords: alireza; amir; hamid; hossein; mohammad; seyed; zahra cache: jovr-12415.pdf plain text: jovr-12415.txt item: #69 of 284 id: jovr-12719 author: Christopher, Mark title: Editorial – Application of Artificial Intelligence to Improve Imaging in Ophthalmology date: 2023-02-13 words: 1049 flesch: 28 summary: BY KNOWLEDGE E 1 http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v18i1.12719&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR Editorial; Christopher set, they have reported performances comparable to previous studies in terms of DICE (a commonly used metric for image segmentation) and even exceeding prior results in terms of R2when comparing mean RNFL thickness to manual segmentation-based RNFL thickness values. Ronneberger O, Fischer P, Brox T. U-net: Convolutional networks for biomedical image segmentation. keywords: learning; segmentation cache: jovr-12719.pdf plain text: jovr-12719.txt item: #70 of 284 id: jovr-12720 author: Steinberg, Johannes ; Mehlan, Juliane ; Mudarisov, Bulat ; Katz, Toam ; Druchkiv, Vasyl ; J Linke, Stephan; Frings, Andreas title: Safety and Precision of Two Different Flap-morphologies Created During Low Energy Femtosecond Laser-assisted LASIK date: 2023-02-13 words: 6196 flesch: 56 summary: When comparing these subgroups, we couldn’t demonstrate any statistical relevant differences among the four subgroups for either 3D or 2D flaps, neither when comparing the totals of the four subgroups of 3D with the totals of the four subgroups of 2D (all P > 0.05). No OBL was found in nine eyes that received 2D flaps (81.8%) or six eyes that received 3D flaps (54.5%), respectively (P = 0.453). keywords: eyes; femto; flap; geometry; laser; lasik; mean; study cache: jovr-12720.pdf plain text: jovr-12720.txt item: #71 of 284 id: jovr-12721 author: Sabbaghi, Hamideh ; Mohammad-Rabei, Hossein ; Karimian, Farid ; Kheiri, Bahareh ; Ali Javadi, Mohammad title: Risk Factors Associated with Keratoconus in an Iranian Population date: 2023-02-13 words: 5073 flesch: 56 summary: KCN patients were all registered at the Iranian National Registry of Keratoconus (KCNReg®). Furthermore, we observed that KCN patients had higher percentages of parental consanguinity, which is in line with previous studies reporting a high prevalence of KCN among populations of Pakistan, Western Mediterranean countries, and India who have a high percentage of consanguine marriages.[10, 15, 33, 34] Due to the 20 JOURNAL OF OPHTHALMIC AND VISION RESEARCH Volume 18, Issue 1, January-March 2023 Risk Factors for Keratoconus; Mohammad-Rabei et al Table 4. keywords: control; eye; factors; kcn; keratoconus; patients; research; risk; study cache: jovr-12721.pdf plain text: jovr-12721.txt item: #72 of 284 id: jovr-12723 author: Jafarinasab, Mohammad-Reza ; Hassanpour, Kiana ; Khosravi, Behrooz ; Esfandiari, Hamed ; Hooshmandi, Sadid title: A Modified Formula for Intraocular Lens Power Calculation Based on Aphakic Refraction in a Pediatric Population date: 2023-02-13 words: 3593 flesch: 50 summary: Intraocular lens (IOL) power calculation remains a challenging issue in the pediatric population.[1] There are two methods of IOL power calculation that are most commonly used in aphakic children including the use of either biometric formulas or refractive vergence formulas. The refractive vergence formulas that use AR instead of AL and keratometry could be used in assessing IOL power calculations for aphakic children. keywords: aphakic; formula; iol; power; refraction cache: jovr-12723.pdf plain text: jovr-12723.txt item: #73 of 284 id: jovr-12724 author: Hejazi, Marjaneh ; Razaghi, Ghazale ; Aghsaei Fard, Masoud title: Correction of Retinal Nerve Fiber Layer Thickness Measurement on Spectral-Domain Optical Coherence Tomographic Images Using U-net Architecture date: 2023-02-13 words: 4599 flesch: 51 summary: Retinal layers segmentation using fully convolutional network in OCT images. However, despite improvements in SD-OCT hardware and software, RNFL segmentation errors are still rather common. keywords: algorithm; figure; images; layer; measurement; net; oct; rnfl; segmentation; test; thickness cache: jovr-12724.pdf plain text: jovr-12724.txt item: #74 of 284 id: jovr-12725 author: Goebel, Collin P.; Sheibani, Nader ; Song, Yong-Seok ; S. Zaitoun, Ismail; Wang, Shoujian ; A. D. Potter, Heather; M. Sorenson, Christine title: Adenosine Receptors Expression in Human Retina and Choroid with Age-related Macular Degeneration date: 2023-02-13 words: 4937 flesch: 48 summary: Slides were incubated at room temperature for 4 h allowing the visualization of collagen in the vasculature and adenosine receptor expression. Eyes with dry AMD lost expression of A3 in the photoreceptor outer segments compared with eyes from control or wet AMD. Conclusion: The ocular presence of adenosine receptors is consistent with their proposed role in modulation of inflammation in both the retina and choroid, and their potential targeting for AMD treatment. keywords: a2a; adenosine; adenosine receptors; amd; choroid; dry; expression; eyes; human; receptors; retina; sections; staining; wet cache: jovr-12725.pdf plain text: jovr-12725.txt item: #75 of 284 id: jovr-12728 author: Ittarat, Mantapond ; Chansaengpetch, Supakorn ; Chansangpetch, Sunee title: Incidence and Risk Factors for Retinopathy of Prematurity at a Rural Tertiary Hospital in Thailand date: 2023-02-13 words: 4066 flesch: 52 summary: No antenatal factor was identified as a predictor or risk factor of ROP development. Using stepwise multivariable logistic regression [Table 2], the following were significant risk factors for ROP development: lighter BW (OR 0.997, 95% CI 0.994–0.999, P = 0.005), male gender (OR 4.907, 95% CI 1.079–22.325, P = 0.040), and BPD (OR 17.047, 95% CI 1.453–199.946, P = 0.024). keywords: factors; incidence; infants; prematurity; retinopathy; risk; rop; study; thailand cache: jovr-12728.pdf plain text: jovr-12728.txt item: #76 of 284 id: jovr-12729 author: Sadeghi, Elham ; Azimi, Ali ; Abdollahi, Fardad ; Moshksar, Shadi ; Nadi, Maryam ; Reza Farsiani, Amir title: Epidemiological and Clinical Features of Pediatric Open Globe Injuries: A Report from Southern Iran date: 2023-02-13 words: 5205 flesch: 58 summary: Pediatric ocular trauma is the most leading cause of acquired unilateral vision loss in childhood, especially in developing countries.[2] Despite all that has been done to reduce the risk of trauma in children, it remains common worldwide.[3] Ocular injuries are divided into two main groups: closed globe injuries and open globe injuries (OGIs). Prior studies have revealed that ocular injuries most frequently occur at home.[4, 12, 23] keywords: age; cases; children; eye; globe; injuries; injury; ogi; open; pediatric; study; trauma; years cache: jovr-12729.pdf plain text: jovr-12729.txt item: #77 of 284 id: jovr-12731 author: Feizi, Mohadeseh ; R. Isen, Danielle ; Tavakoli, Mehdi title: Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 and Its Vaccination: A Narrative Review date: 2023-02-13 words: 6449 flesch: 47 summary: Dinkin M, Gao V, Kahan J, Bobker S, Simonetto M, Wechsler P, et al. COVID-19 presenting with ophthalmoparesis from cranial nerve palsy. Dreyer-Alster S, Menascu S, Mandel M, Shirbint E, Magalashvili D, Dolev M, et al. COVID-19 vaccination in patients with multiple sclerosis: Safety and humoral efficacy of the third booster dose. keywords: acute; case; coronavirus; cov-2; covid-19; disease; et al; infection; manifestations; nerve; neuritis; neuro; ophthalmic; optic; palsy; patients; pupil; report; sars; syndrome; tonic; vaccination; vision cache: jovr-12731.pdf plain text: jovr-12731.txt item: #78 of 284 id: jovr-12732 author: Sharma, Ashok ; Sharma, Rajan ; S. Nirankari, Verinder title: Retrocorneal Scleral Patch Supported Glue: A Technique for Management of Corneal Perforation and Corneoscleral Melt following Pterygium Surgery date: 2023-02-09 words: 2631 flesch: 46 summary: (c) Healed corneal perforation (sclera patch in place) and pseudo-pterygium at 12 weeks’ follow-up. Diagramatic presentation of retrocorneal sclera patch supported cyanoacrylate tissue adhesive application: (a) Corneal perforation (3.5×3.5 mm), corneal, limbal and sclera melt; (b) Punching of sclera patch (4.5×4.5 mm) using a skin bopsy punch; (c) Placing the thinned sclera patch behind the corneal perforation; (d) Application of minimum quantity of cyanoacrylate tissue adhesive at the margin of perforation on the sclera patch; (e) Injecting an air bubble in the anterior chamber; (f) keywords: adhesive; corneal; cyanoacrylate; patch; perforation; pterygium; scleral cache: jovr-12732.pdf plain text: jovr-12732.txt item: #79 of 284 id: jovr-12734 author: Piri, Niloofar ; P. Kung, George; D. Clark, Jeremy ; Gerber, Austin title: Tantalum Surgical Clip Presenting As an Intraorbital Foreign Body date: 2023-02-13 words: 928 flesch: 52 summary: Metallic foreign body was revealed to be a tantalum surgical clip. (A) Intraoperative X-ray demonstrating metallic foreign body in left orbit to be symmetric surgical clip. keywords: body; clip; left; tantalum cache: jovr-12734.pdf plain text: jovr-12734.txt item: #80 of 284 id: jovr-12735 author: Tzamalis, Argyrios ; D. Christou, Chrysanthos; Prousali, Efthymia ; Ziakas, Nikolaos title: What is the Real Cost of Intraoperative Floppy Iris Syndrome in Cataract Surgery? date: 2023-02-13 words: 1489 flesch: 49 summary: Average cost of surgical consumables and surgical duration in uneventful cataract surgeries along with respective comparison between cases with or without IFIS. Extra cost from surgical consumables per case (Euros - €) 60.3 Extra cost from prolonged surgical time per case (Euros - €) 41.04 Total extra cost per case (Euros - €) 101.34 ∗Assessed with Student’s t-test. keywords: cases; cataract; cost; ifis; surgery cache: jovr-12735.pdf plain text: jovr-12735.txt item: #81 of 284 id: jovr-13178 author: Mashayekhi, Arman title: Editorial – Surgically Managed Orbital Tumors: A Case Series from a Referral Center in Iran date: 2023-04-19 words: 1260 flesch: 44 summary: For example, in a study on pediatric orbital tumors from Turkey, secondary orbital retinoblastoma accounted for 33% of cases, a rate much higher than that reported from more economically developed countries.[1] The selection criteria of the study affect the reported incidence of orbital tumors in many ways. Editorial Surgically Managed Orbital Tumors: A Case Series from a Referral Center in Iran Arman Mashayekhi, MD Ophthalmology Department, Mayo Clinic, Jacksonville, FL, USA ORCID: Arman Mashyekhi: https://orcid.org/0000-0002-1739-1322 J Ophthalmic Vis Res 2023; 18 (2): 141–142 The spectrum of orbital tumors is wide, including a variety of benign and malignant neoplasms. keywords: center; patients; study; tumors cache: jovr-13178.pdf plain text: jovr-13178.txt item: #82 of 284 id: jovr-13180 author: Shamseldin Shalaby, Wesam ; Patel, Sonali; Lam, Sophia; Ganjei, Allen; Garg Shukla, Aakriti ; Kolomeyer, Natasha; Lee, Daniel; Katz, L. Jay; Moster, Marlene; Myers, Jonathan; Razeghinejad, Reza title: Effect of Phacoemulsification on Intraocular Pressure in Eyes with Functioning Tube Shunts date: 2023-04-19 words: 3655 flesch: 54 summary: Yasutani H, Hayashi K, Hayashi H, Hayashi F. Intraocular pressure rise after phacoemulsification surgery in glaucoma patients. BY KNOWLEDGE E http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v18i2.13180&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR Phacoemulsification after Tube Shunts; Shalaby et al INTRODUCTION Cataract surgery in patients with preexisting glaucoma or glaucoma surgery is challenging considering the potential impairment of postoperative intraocular pressure (IOP) control. keywords: cataract; eyes; failure; glaucoma; iop; patients; phacoemulsification; surgery; tube cache: jovr-13180.pdf plain text: jovr-13180.txt item: #83 of 284 id: jovr-13181 author: Yang, Michael; Yang, Christopher; Lin, Ken title: How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study date: 2023-04-19 words: 3795 flesch: 49 summary: Tube fenestrations were created using a spatulated suture needle (Ethicon, 7-0 Vicryl, TG140-8 needle) by entering perpendicularly to the center of and passing through the front and far side of the tubing. Future experiments can be performed to expand on our study by conducting experiments between the 10 mmHg intervals, determining the effect of interfenestration distance on opening pressure, studying the effect of fenestration numbers greater than two, and quantifying the microarchitecture of manually created fenestrations. keywords: egress; fenestrations; fluid; glaucoma; iop; mmhg; pressure; silicone; tube cache: jovr-13181.pdf plain text: jovr-13181.txt item: #84 of 284 id: jovr-13182 author: Moradian, Siamak; Soheilian, Masoud; Asadi, Mahsan; Baghi, Abdolreza; Safi, Hamid; Abtahi, Seyed-Hossein title: Ziv-aflibercept in Diabetic Macular Edema: Relation of Subfoveal Choroidal Thickness with Visual and Anatomical Outcomes date: 2023-04-19 words: 3339 flesch: 51 summary: Correlation between central macular thickness changes, best corrected visual acuity changes, and subfoveal choroidal thickness changes at one, two, and three months after monthly injection of intravitreal ziv-aflibercept. Sarda V, Eymard P, Hrarat L, Fajnkuchen F, Giocanti- Aurégan A. Comparison of the effect of ranibizumab and aflibercept on changes in macular choroidal thickness in patients treated for diabetic macular edema. keywords: aflibercept; changes; dme; intravitreal; ivz; patients; sct; thickness; ziv cache: jovr-13182.pdf plain text: jovr-13182.txt item: #85 of 284 id: jovr-13183 author: Ebrahimiadib, Nazanin; Hadavand Mirzaei, Shaghayegh ; Riazi-Esfahani, Hamid ; Amini, Manouchehr title: Renal Function following Fluorescein Angiography in Diabetic Patients with Chronic Kidney Disease date: 2023-04-19 words: 2735 flesch: 55 summary: Methods: Diabetic patients with retinopathy who were candidate for fundus fluorescein angiography (FA) were evaluated for serum creatinine and urea levels within five days prior to performing the FA. In this study, we are going to determine whether the fluorescein can cause contrast-induced AKI in diabetic patients with CKD who are candidates for fundus FA. keywords: ckd; creatinine; fluorescein; kidney; patients; study cache: jovr-13183.pdf plain text: jovr-13183.txt item: #86 of 284 id: jovr-13184 author: Mirzaee Saba, Leila ; Hashemi, Hassan; Jafarzadehpour, Ebrahim; Mirzajani, Ali; Yekta, Abbasali; Jafarzadehpour, Abolfazl; Zarei, Arghavan; Nabovati, Payam; Khabazkhoob, Mehdi title: P100 Wave Latency and Amplitude in Visual Evoked Potential Records in Different Visual Quadrants of Normal Individuals date: 2023-04-19 words: 4070 flesch: 52 summary: In this study, the mean P100 amplitude and latency were assessed in different visual field areas of 80 eyes of 40 patients with a mean age of 23.25 ± 3.44 years. Assessment of the pattern visual evoked potential (PVEP) responses in different areas of visual fields in individuals with normal vision. keywords: amplitude; areas; field; inferior; latency; nasal; p100; pvep; study; temporal; visual cache: jovr-13184.pdf plain text: jovr-13184.txt item: #87 of 284 id: jovr-13185 author: Bhardwaj, Amit; Vashist, Praveen; Singh Senjam, Suraj ; Gupta, Vivek; Gupta, Noopur; Manna, Souvik title: Rapid Assessment of Avoidable Visual Impairment in Two Coastal Districts of Eastern India for Determining Effective Coverage: A Cross-Sectional Study date: 2023-04-19 words: 5501 flesch: 61 summary: Combined % (95% CI) Unstandardized prevalence (%) Standardized prevalence (%) Definition Male (N = 1677) Female (N = 2068) The impact of REs is manifold and includes loss of livelihood, schooling, and financial resources.[23] Estimates of global economic burden of distant VI due to URE is huge (US$ 202 billion).[24] Globally, nearly 800 million people suffer from distance VI (i.e., myopia and hypermetropia) or near VI (i.e., presbyopia) who need just a pair of spectacles, while another 100 million persons have moderate-to-severe distance VI or blindness that is amenable by cataract surgery.[25] keywords: blindness; cataract; districts; impairment; india; odisha; population; prevalence; study; vision; visual cache: jovr-13185.pdf plain text: jovr-13185.txt item: #88 of 284 id: jovr-13186 author: Alsaqr, Ali title: Eye Care in Young Children: A Parents’ Perspective of Access and Barriers date: 2023-04-19 words: 6068 flesch: 58 summary: Knowledge and practices of parents about child eye health care in the public sector in Swaziland. The perception, awareness, and level of accepted responsibilities of these individuals could play a crucial role in the efficacy of child vision screening programs and the development of policies for school and preschool-age children.[24, 29–31] A study conducted in England reported that approximately 30% of children did not attend follow-up visits after failing screening tests at schools’ entry year.[9] Several studies have emphasized the importance of parents’ awareness in combating children’s visual problems.[29–32] keywords: care; children; eye; eye care; parents; responses; saudi; screening; services; study; test; vision; year cache: jovr-13186.pdf plain text: jovr-13186.txt item: #89 of 284 id: jovr-13187 author: Bagheri, Abbas; Ashtar-nakhaie, Parisa ; Aletaha, Maryam; Kheiri, Bahareh; Veisi, Amirreza title: A Survey on Orbital Space-occupying Lesions during a Twelve-year Period from a Referral Center in Iran date: 2023-04-19 words: 4592 flesch: 53 summary: In our series, benign orbital lesions outnumbered malignant lesions by 4.7 times which is comparable to the report by Kodsi et al,[11] however, in some of the other studies this predominance of benign lesions was less significant,[2, 6, 8, 12] which may be due to the younger age of our study population. Orbital lesions ≤18 years 19–59 years ≥60 years Benign (numbers) Dermoid cyst (113) 73 39 1 Cavernous hemangioma (66) 4 56 6 Pseudotumor (17) 3 13 1 Pleomorphic adenoma (11) 1 6 4 Lymphangioma (13) 10 3 0 Schwannoma (9) 2 7 0 Others (80) 19 54 7 309 (82.4% of total) 112 (36.2% of benign) 178 (57.6% of benign) 19 (6.2% of benign) keywords: age; benign; lesions; malignant; ophthalmic; orbital; patients; space; study; total; tumors cache: jovr-13187.pdf plain text: jovr-13187.txt item: #90 of 284 id: jovr-13771 author: Riazi, Mohammad title: The Impact of COVID-19 on Ophthalmology Practice: Changes and Controversies in Endophthalmitis Risk date: 2023-07-23 words: 1377 flesch: 40 summary: Tight-fitting face masks used without adhesive tapes resulted in the highest amount of bacterial growth around the subject’s eye.[1] Sakamoto et al reported an increased rate of post-vitrectomy endophthalmitis in the COVID era, with more germs originating from the oral cavity.[2] Several case reports have shown a link between COVID-19 and ocular disorders, including conjunctivitis, keratitis, uveitis, and retinal vascular occlusions. These authors compared 28,085 injections in the pre-COVID era with 10,717 injections during the COVID era and found no significant differences in the rate of endophthalmitis after injections (0.032% in pre-COVID era vs 0.037% in COVID era). keywords: covid-19; endophthalmitis; era; ophthalmic; pandemic cache: jovr-13771.pdf plain text: jovr-13771.txt item: #91 of 284 id: jovr-13773 author: Beheshtnejad, Amir-Hooshang ; Ghassemi, Hamed ; Abdolkhalegh, Hossein ; Atighehchian, Mehrnaz title: Clinical and Autofluorescence Findings in Eyes with Pinguecula and Pterygium date: 2023-07-23 words: 3453 flesch: 48 summary: So, the mean size of the autofluorescence area displayed in AS- AF imaging was 9.19 mm2 larger than the mean size of the pinguecula displayed in slit-lamp photography (P = 0.001). AF imaging can reveal any changes in various retinal diseases based on RPE lipofuscin deposits.[10] These lipofuscin granules contain specified fluorophores that are responsible for creating FAF imaging.[5, 7] keywords: autofluorescence; imaging; lamp; patients; photography; pinguecula; pterygium; size; slit cache: jovr-13773.pdf plain text: jovr-13773.txt item: #92 of 284 id: jovr-13774 author: Monteiro, Catarina ; Vivas, Maria ; Almeida, Júlio ; Ramalho, Mário ; Mota, Mafalda ; Teixeira, Susana ; Prieto, Isabel title: Intraocular Pressure Values using Icare® Rebound Tonometer and Correlation with Postconceptional Age in Premature Infants date: 2023-07-23 words: 2590 flesch: 55 summary: The evaluated outcomes were mean IOP values and their correlation with PCA. Box and whisker plot of IOP values. keywords: infants; iop; mmhg; pca; study; values; weeks cache: jovr-13774.pdf plain text: jovr-13774.txt item: #93 of 284 id: jovr-13776 author: Karimi, Saeed ; Nikkhah, Homayoun ; Mohammadzadeh, Amir ; Ramezani, Alireza ; Ansari, Iman ; Nouri, Hosein ; Abtahi, Seyed-Hossein title: Intravitreal Injections and Face Masks: Endophthalmitis Risk Before and During the COVID-19 Pandemic date: 2023-07-23 words: 3691 flesch: 44 summary: While some have suggested an additional risk of endophthalmitis with patients wearing masks during the sessions— theoretically, through an upward direction of exhaled vapors toward the periocular area, increasing the risk of infectious complications,[10] others have found no increase in the overall risk of endophthalmitis, attributable to using face.[11] In the present study, we investigated the effect of these changes in health protocols during the COVID pandemic on the incidence of post-intravitreal injections endophthalmitis and compared the endophthalmitis rate during the COVID pandemic with the rate at which it occurred during the pre-COVID era. The importance of intravitreal injections, especially intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections, has increased in recent years due to their widespread use in managing retinal diseases such as diabetic macular edema (DME) and neovascular age- related macular degeneration (nAMD).[1] Along with its therapeutic benefits, the intravitreal delivery route carries the risk of some side effects and complications, including subconjunctival hemorrhage, uveitis, retinal tear or detachment, and endophthalmitis.[2, 3] Endophthalmitis is a severe, sight-threatening complication of intravitreal injections; among its known risk factors are diabetes mellitus (DM), blebs, blepharitis, etc.[3, 4] Adherence to standard injection protocol can significantly limit the incidence of post-intravitreal injection endophthalmitis.[3, 5] Alterations in the former may give rise to changes in the latter. keywords: covid; endophthalmitis; era; face; injections; intravitreal; ivb; patients; pre; risk cache: jovr-13776.pdf plain text: jovr-13776.txt item: #94 of 284 id: jovr-13777 author: H Fortes, Blake ; D Tailor, Prashant; T Xu, Timothy ; A Churchill, Robert ; R Starr, Matthew title: Clinical Characteristics and Outcomes of Endophthalmitis Before and During the COVID-19 Pandemic date: 2023-07-23 words: 4395 flesch: 46 summary: Wong RLM, Ting DSW, Wan KH, Lai KHW, Ko CH, Ruamviboonsuk P, et al. COVID-19: [Snellen VA: 20/96] vs. COVID-19 LogMAR VA: 0.41 keywords: covid-19; covid-19 pandemic; endophthalmitis; injection; outcomes; pandemic; patients; post; presentation; study cache: jovr-13777.pdf plain text: jovr-13777.txt item: #95 of 284 id: jovr-13779 author: Kegne Assaye, Aragaw ; Temeselew Tegegn, Melkamu ; Tilahun Belete, Gizachew title: Eye Care Utilization among Older Subjects with Visual Impairment in Northwest Ethiopia date: 2023-07-23 words: 6770 flesch: 61 summary: The utilization of eye care services within the past two years prior to the study was 21.1% (95 % CI: 18.2–23.9). Conclusion: In this study, utilization of eye care services was low. keywords: care services; distance; ethiopia; eye care; health; impairment; ophthalmic; participants; services; study; utilization; vision; years cache: jovr-13779.pdf plain text: jovr-13779.txt item: #96 of 284 id: jovr-13780 author: Moghadam Fard, Atousa ; Mirshahi, Reza ; Naseripour, Masood ; Ghasemi Falavarjani, Khalil title: Stem Cell Therapy in Stargardt Disease: A Systematic Review date: 2023-07-23 words: 6676 flesch: 48 summary: Retinal detachment after subretinal stem cell transplantation. Stem cells are able to differentiate into various kinds of cell types to replace lost or damaged cells.[12] Several studies have been conducted to determine the safety and efficacy of stem cell therapy for Stargardt disease.[13–25] keywords: acuity; cell therapy; cells; disease; et al; eyes; hesc; human; macular; patients; rpe; stargardt; stargardt disease; stem; stem cell; studies; study; subretinal; therapy; transplantation; visual cache: jovr-13780.pdf plain text: jovr-13780.txt item: #97 of 284 id: jovr-13783 author: Kerley, Madison ; Piri, Niloofar ; Ramasubramanian, Aparna title: Diffuse Pigment Release in a Patient Undergoing Tumor-Infiltrating Lymphocyte Immunotherapy for Acral Malignant Melanoma date: 2023-07-23 words: 905 flesch: 40 summary: Although TIL has proven to be a powerful treatment for metastatic melanoma, it can lead to melanocyte-reactive T cells in other melanocyte containing regions.[3] Herein, we present a unique case of acral metastatic melanoma, treated by adoptive cell transfer leading to asymptomatic intraocular pigmentary changes. Symptoms often parallel those of VKH disease, which demonstrates a heightened immune response to tyrosinase450−462 and gp10044−59, two melanocyte antigens found in the ears, skin, hair, meninges, and eyes.[4] Our patient did not demonstrate dermatologic manifestations such as vitiligo and poliosis in contrast to Yeh et al’s 2009 case.[4] keywords: kerley; melanoma; pigment; tumor cache: jovr-13783.pdf plain text: jovr-13783.txt item: #98 of 284 id: jovr-4778 author: Foroozan, Rod title: Editorial: Erythropoietin for Optic Neuritis date: 2019-07-18 words: 1513 flesch: 48 summary: This is the type of optic neuropathy most commonly referred to as “optic neuritis.” Given the persistent deficits that remain after a bout of optic neuritis, there remains an unmet need for neuroprotective therapy. keywords: erythropoietin; neuritis; neuropathy; optic; treatment cache: jovr-4778.pdf plain text: jovr-4778.txt item: #99 of 284 id: jovr-4780 author: Mirshahi, Alireza; A. Ponto, Katharina title: Changes in Pupil Area During Low-energy Femtosecond Laser Assisted Cataract Surgery date: 2019-07-18 words: 3845 flesch: 52 summary: Another possible explanation for our obser- vation of unchanged pupil area could be the time lapse between the femtosecond laser pretreatment and other surgical parts: When using the Ziemer Z8 laser, the surgery can be continued immediately after the completion of laser pretreatment, while in other lasers, the patient must be transferred to another surgical table or theatre. We measured the pupil diameters as part of the images taken preoperatively and at the completion of laser pretreatment (after releasing the suction). keywords: area; cataract; energy; eyes; femtosecond; flacs; laser; pupil; study; surgery cache: jovr-4780.pdf plain text: jovr-4780.txt item: #100 of 284 id: jovr-4781 author: Bawankar, Pritam; Bhattacharjee, Harsha; Barman, Manabjyoti; Soibam, Ronel; Deka, Hemalata; Chandra Kuri, Ganesh ; Medhi, Jnanankar title: Outbreak of Multidrug-resistant Pseudomonas Aeruginosa Endophthalmitis Due to Contaminated Trypan Blue Solution date: 2019-07-18 words: 7192 flesch: 54 summary: Pseudomonas aeruginosa endophthalmitis after cataract surgery in 13 patients and determine the importance of associated risk factors, clinical profile, microbiological analysis, early diagnosis, and therapy. In a recent study by Eifrig et al,[13] 18 of 28 eyes with Pseudomonas aeruginosa endophthalmitis either developed phthisis bulbi or were eviscerated, and none of the remaining nine patients achieved a final visual acuity of 5/200 or better. keywords: aeruginosa; cataract; e n; endophthalmitis; outbreak; patients; pseudomonas; pseudomonas aeruginosa; surgery cache: jovr-4781.pdf plain text: jovr-4781.txt item: #101 of 284 id: jovr-4782 author: Razeghinejad, Reza; Hossein Nowroozzadeh, M. title: Water-drinking Test and Pharmacologic Mydriasis as Provocative Tests in Primary Angle Closure Suspects date: 2019-07-18 words: 4784 flesch: 53 summary: In a study on patients with PACS, PAC, and PACG, the positive dark room and mydriasis tests were defined as an increase in IOP of 6 mmHg. Intraocular pressure fluctuation after water drinking test in primary angle-closure glaucoma and primary open-angle glau- coma. keywords: angle; closure; drinking; iop; lpi; mydriasis; ophthalmol; pacs; patients; test; water; wdt cache: jovr-4782.pdf plain text: jovr-4782.txt item: #102 of 284 id: jovr-4783 author: Y. Lin, Ken ; Mosaed, Sameh title: Ab Externo Imaging of Human Episcleral Vessels Using Fiberoptic Confocal Laser Endomicroscopy date: 2019-07-18 words: 5079 flesch: 52 summary: Episcleral vessel diameter distribution along the limbal perimeter in human eyes. How to cite this article: Lin KY, Mosaed S. Ab externo imaging of human episcleral vessels using fiberoptic confocal laser endomicroscopy. keywords: eyes; figure; fluorescein; human; image; imaging; laser; microendoscope; study; time; vessels cache: jovr-4783.pdf plain text: jovr-4783.txt item: #103 of 284 id: jovr-4784 author: Torabi, Hamidreza; Saberi Isfeedvajani, Mohsen ; Ramezani, Majid; Daryabari, Seyed-Hashem title: Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus date: 2019-07-18 words: 3836 flesch: 55 summary: In this study, we found that the choroidal thick- ness in non-diabetic patients was significantly greater than in diabetic patients. Conclusion: HbA1c values have a significant correlation with choroidal thickness in diabetic patients, and better glycemic control with HbA1c ≤ 7% may prevent choroidal thinning. keywords: control; diabetic; eyes; group; hba1c; non; patients; study; thickness; 𝑃 = cache: jovr-4784.pdf plain text: jovr-4784.txt item: #104 of 284 id: jovr-4785 author: Zarei, Mohammad; Bazvand, Fatemeh; Ebrahimiadib, Nazanin; Roohipoor, Ramak; Karkhaneh, Reza; Farahani Dastjani, Afsar ; Imani Fouladi, Marjan ; Riazi Esfahani, Mohammad ; Khodabande, Alireza; Davoudi, Samaneh; Ghasemi, Hamed; S Modjtahedi, Bobeck title: Prevalence and Risk Factors of Retinopathy of Prematurity in Iran date: 2019-07-18 words: 4671 flesch: 54 summary: The rate of development of ROP and significant risk factors in some studies Study Sample size Rate of ROP Risk factors Liu et al[13] 1,846 12.8% Birth weight, gestational age, days of oxygen supplementation, and myocardial injury after birth Chen et al[12] 472 12.7% Gestational age, birth weight, preeclampsia, and maternal oxygen supplement before or at the time of delivery Port et al[6] 1,354 38.8% Birth weight, gestational age, bronchopulmonary dysplasia, multiple gestation (MG), necrotizing enterocolitis, race and ethnicity Mohamed et al[17] 582 29% Univariate analysis: birth weight, gestational age, patent ductus arteriosus, sepsis, intraventricular hemorrhage (IVH), lung disease, days of hyperglycemia, and prescription of postnatal steroids Multivariate analysis: gestational age, days of hyperglycemia, and days of mechanical ventilation Bossi et al[9] 639 11.4% Frequency, outcomes, and risk factor analysis. keywords: age; birth; factors; infants; patients; prematurity; retinopathy; risk; risk factors; rop; weight cache: jovr-4785.pdf plain text: jovr-4785.txt item: #105 of 284 id: jovr-4786 author: Soltan Sanjari, Mostafa ; Pakdel, Farzad; Moosavi, Fatemeh; Pirmarzdashti, Niloofar; Nojomi, Marzieh; Haghighi, Anoosheh; Hashemi, Masih; Bahmani Kashkouli, Mohsen title: Visual Outcomes of Adding Erythropoietin to Methylprednisolone for Treatment of Retrobulbar Optic Neuritis date: 2019-07-18 words: 4176 flesch: 48 summary: In the future, randomized clinical trials with larger sample size may reveal statistically significant differences in the visual outcome after erythropoietin treatment. Fishbane S, Besarab A. Mechanism of increased mortality risk with erythropoietin treatment to higher hemoglobin targets. keywords: acuity; days; erythropoietin; group-2; methylprednisolone; neuritis; optic; patients; study; treatment; visual cache: jovr-4786.pdf plain text: jovr-4786.txt item: #106 of 284 id: jovr-4787 author: Hashemi, Hassan; Pakbin, Mojgan; Ali, Babak; Yekta, Abbasali; Ostadimoghaddam, Hadi; Asharlous, Amir; Aghamirsalim, Mohammadreza; Khabazkhoob, Mehdi title: Near Points of Convergence and Accommodation in a Population of University Students in Iran date: 2019-07-18 words: 5079 flesch: 57 summary: Some studies reported a relationship between heterophoria and refractive error,[16, 17] while another claimed that the NPC was not related to refractive error.[15] Accurate interpretation of NPC measurements requires their comparison with normal values, which may vary from one population to another. To increase measurement accuracy, NPC measurements were performed three times for each individual, and the average of the three measurements was recorded as the final NPC. keywords: accommodation; age; convergence; npa; npc; point; students; study; university; years cache: jovr-4787.pdf plain text: jovr-4787.txt item: #107 of 284 id: jovr-4789 author: Ekici Gok, Zarife ; Gunduz, Abuzer; Cankaya, Cem title: Effect of Fasting on Contrast Sensitivity in Healthy Males date: 2019-07-18 words: 2875 flesch: 57 summary: The comparison of contrast sensitivity measurements conducted in the Ramadan 1st and 4th week Spatial frequency (cpd) Ramadan first week measurement (mean ± SD) Ramadan fourth week measurement (mean ± SD) P-value A (1.5) 71.78 ± 21.58 75.75 ± 21.88 0.10 B (3) 128.52 ± 24.25 128.84 ± 24.42 0.91 C (6) 123.02 ± 31.40 128.40 ± 26.18 0.47 D (12) 71.89 ± 26.22 76.35 ± 27.61 0.83 E (18) 25.91 ± 14.43 25.95 ± 13.20 0.76 cpd, cycles per degree; SD, standard deviation When considering CS function in the human eye from very low spatial frequencies to very high spatial frequencies, in general, we observe a continuous decrease. The comparison of contrast sensitivity measurements conducted before the Ramadan and at the fourth week of Ramadan Spatial frequency (cpd) Measurement before Ramadan (mean ± SD) Ramadan fourth week measurement (mean ± SD) P-value A (1.5) 70.87 ± 22.52 75.75 ± 21.88 0.17 B (3) 118.45 ± 22.22 128.84 ± 24.42 0.01* C (6) 122.82 ± 30.38 128.40 ± 26.18 0.49 D (12) 65.85 ± 25.55 76.35 ± 27.61 0.01* E (18) 23.57 ± 1.42 25.95 ± 13.20 0.13 cpd, cycles per degree; SD, standard deviation Table 4. keywords: contrast; cpd; fasting; ramadan; sensitivity; week cache: jovr-4789.pdf plain text: jovr-4789.txt item: #108 of 284 id: jovr-4790 author: Sadat Mahmoudi Nezhad, Golnoush ; Razeghinejad, Reza ; Janghorbani, Mohsen; Mohamadian, Alireza; Hassan Jalalpour, Mohammad ; Bazdar, Somaye; Salehi, Alireza; Molavi Vardanjani, Hossein title: Prevalence, Incidence and Ecological Determinants of Diabetic Retinopathy in Iran: Systematic Review and Meta-analysis date: 2019-07-18 words: 9483 flesch: 57 summary: Type of diabetes was not a sig- nificant determinant of heterogeneity for individual estimates of DR prevalence (𝑃 = 0.10). The pooled estimate of DR prevalence was 48.8% (95% CI: 42.7, 55.0) in studies including only type II diabetics and 64.6% (95% CI: 62.2, 67.0) in studies including both types of diabetes. keywords: clinics; diabetes; diabetic; dr prevalence; estimates; et al; eye; incidence; iran; lin; m c; number; patients; population; prevalence; retinopathy; studies; study; type cache: jovr-4790.pdf plain text: jovr-4790.txt item: #109 of 284 id: jovr-4791 author: Lashay, Alireza; Riazi-Esfahani, Hamid ; Mirghorbani, Masoud; Yaseri, Mehdi title: Intravitreal Medications for Retinal Vein Occlusion: Systematic Review and Meta-analysis date: 2019-07-18 words: 25288 flesch: 65 summary: Scott IU, VanVeldhuisen PC, Ip MS, Blodi BA, Oden NL, Awh CC, et al. Effect of bevacizumab vs aflibercept on visual acuity among patients with macular edema due to central retinal vein occlusion: the SCORE2 randomized clinical trial. A total of 149 patients, with ME sec- ondary to RVO, were enrolled in three studies (Ramezani et al,[21] Ding et al,[22] and Cekic[66] et al). keywords: c m; co m; e g; e m; e n; ea n; g gr; g s; gr ou; io n; ix m; m ea; m g; m m; m t; n d; n o; r e; r gr; study; th e; th s cache: jovr-4791.pdf plain text: jovr-4791.txt item: #110 of 284 id: jovr-4792 author: Subhash Joshi, Rajesh title: Corneal Toxicity due to Datura Inoxia date: 2019-07-18 words: 2053 flesch: 63 summary: However, to the best of our knowledge, there are no reports of datura corneal toxicity. Datura Inoxia Rajesh Subhash Joshi, DNB, MS (Ophth) Department of Ophthalmology, Shri Vasantrao Naik Government Medical College, Yavatmal, India ORCID: Rajesh Subhash Joshi: https://orcid.org/0000-0001-5646 Abstract Purpose: To report corneal toxicity following intentional inoculation of the juice of crushed leaves of datura (Datura Inoxia). keywords: corneal; datura; eye; juice; leaves; patient; toxicity cache: jovr-4792.pdf plain text: jovr-4792.txt item: #111 of 284 id: jovr-4793 author: Hatami, Mohammadmehdi; Doozandeh, Azadeh; Feizi, Mohadeseh title: Glaucoma in Ectropion Uveae Syndrome: a Case Report and Literature Review date: 2019-07-18 words: 2189 flesch: 54 summary: After starting glaucoma medication, IOP decreased to 21 mmHg. Slit lamp view shows ectropion uvea in left eye. keywords: ceu; ectropion; eye; figure; glaucoma; iris; syndrome cache: jovr-4793.pdf plain text: jovr-4793.txt item: #112 of 284 id: jovr-4794 author: Karimi, Saeed; Pahlevani, Pouyan title: Tapioca Melanoma of the Iris: a Case Report date: 2019-07-18 words: 2288 flesch: 55 summary: Therefore, diagnosis of atypical iris melanomas may be difficult and challenging.[2, 7] Early diagnosis and treatment of atypical iris melanomas are essential for preventing the progression of the disease and saving the patients’ eyesight and life.[8, 9] CASE REPORT A 50-year-old male patient presented with ocu- lar pain and redness in the right eye for two weeks. The mean age of surgery in tapioca melanoma patients was 30 years, whereas in other types of iris melanoma it was 46.[3] keywords: case; figure; iop; iris; melanoma; ophthalmol; tapioca; tumor cache: jovr-4794.pdf plain text: jovr-4794.txt item: #113 of 284 id: jovr-4796 author: Bhattacharjee, Kasturi; Singh, Manpreet; Das, Dipankar; Bhattacharjee, Harsha title: Subconjunctival and Orbital (Twin) Cysticercosis in a Child date: 2019-07-18 words: 1260 flesch: 47 summary: 2. Bhatia K, Sengupta S, Sharma S. Spontaneous extrusion of subconjunctival cysticercosis cyst. 3. Obedulla H, Pujari A, Gupta Y, Basheer S. Spontaneous extrusion of subconjunctival cysticercosis cyst. keywords: cyst; cysticercosis; figure; right cache: jovr-4796.pdf plain text: jovr-4796.txt item: #114 of 284 id: jovr-5435 author: Ghasemi, Hamed; Djalilian, Ali title: Topical Calcineurin Inhibitors: Expanding Indications for Corneal and Ocular Surface Inflammation date: 2019-10-24 words: 1016 flesch: 41 summary: Inflammation and hyperactivity of the immune system play a central role in the pathophysiology of many ocular diseases such as vernal keratoconjunctivitis (VKC), dry eye disease, stromal keratitis, etc. As mentioned earlier, one of the main limitations of both topical cyclosporin and topical tacrolimus is their tolerability which appears to be concentration dependent. keywords: eye; inflammation; tacrolimus; topical cache: jovr-5435.pdf plain text: jovr-5435.txt item: #115 of 284 id: jovr-5439 author: Chatterjee, Arkendu; Bandyopadhyay, Sabyasachi; Kumar Bandyopadhyay, Samir title: Efficacy, Safety and Steroid-sparing Effect of Topical Cyclosporine A 0.05% for Vernal Keratoconjunctivitis in Indian Children date: 2019-10-24 words: 3756 flesch: 52 summary: Patients in the Cs A group were treated with aqueous ophthalmic solution of topical Cs A 0.05% (Hydroeyes 0.05% w/v®; Lupin Ltd., Mumbai, India) in either eye with one drop four times/day, and those in the placebo group were treated with topi- cal carboxymethyl cellulose 0.5% (Refresh tears®; Allergan Inc., Irvine, CA, USA) in either eye with one drop four times/day. In a recent study with 30 VKC patients, Ozlem et al observed that Cs A 0.05% can help in reducing corticosteroid usage and is a safe and effective alternative for the treatment of resistant VKC.[4] Baiza-Duran et al compared 0.1% and 0.05% aqueous formulation of Cs A in 112 Mexican children with VKC and found that both concentrations were safe, effective, and equally well-tolerated.[16] Keklikci et al studied the efficacy of topical Cs A 0.05% in patients with severe VKC and noted significant clinical improvement as well as decreased density of inflammatory cells in conjunctival impression cytology specimens.[20] Akpek et al performed a randomized trial with topical keywords: day; group; keratoconjunctivitis; patients; placebo; steroid; topical; vkc cache: jovr-5439.pdf plain text: jovr-5439.txt item: #116 of 284 id: jovr-5441 author: Gutiérrez, María A; Giuliani, Daniela; Porta, Atilio A; Andrinolo, Darío title: Relationship between Ocular Surface Alterations and Concentrations of Aerial Particulate Matter date: 2019-10-24 words: 5206 flesch: 53 summary: This can lead to various forms of corneal and conjunctival dysfunction such as increasing order of severity, pain and itching,[3] mild corneal abrasion to severe loss of stem cells, decreased vision,[4] and blindness.[5] Ocular surface disorders occur in patients with various conditions including limbal stem-cell defi- ciency and ocular surface disease (OSD) due to systemic diseases.[1] https://orcid.org/0000-0002-3491-6151 Abstract Purpose: To evaluate ocular surface alterations in two populations at different exposure levels to particulate matter (PM) in their living and work environments. keywords: air; dry; eye; film; levels; matter; particulate; pollution; staining; study; surface; tear; values; variables cache: jovr-5441.pdf plain text: jovr-5441.txt item: #117 of 284 id: jovr-5443 author: Khorrami-Nejad, Masoud ; Aghili, Ozra; Hashemian, Hesam; Aghazadeh-Amiri, Mohamad ; Khosravi, Bahram title: Changes in Corneal Asphericity after MyoRing Implantation in Moderate and Severe Keratoconus date: 2019-10-24 words: 4544 flesch: 53 summary: Methods: This cross-sectional observational study comprised 32 eyes of 28 patients with KCN, who had femtosecond-assisted MyoRing corneal implantation. Original Article Changes in Corneal Asphericity after MyoRing Implantation in Moderate and Severe Keratoconus Masoud Khorrami-Nejad1, MS; Ozra Aghili1, MS; Hesam Hashemian2, MD; Mohamad Aghazadeh-Amiri1, OD Farshid Karimi1, MS 1Department of Optometry, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2Eye Research center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran ORCID: Masoud Khorrami-Nejad: https://orcid.org/0000-0002-8270-9704 Hasan Hashemian: https://orcid.org/0000-0003-0836-8937 Abstract Purpose: To evaluate the effect of MyoRing implantation on corneal asphericity in moderate and severe keratoconus (KCN). keywords: asphericity; corneal; implantation; keratoconus; mean; myoring; study; surgery cache: jovr-5443.pdf plain text: jovr-5443.txt item: #118 of 284 id: jovr-5445 author: Moshirfar, Majid; Wagner, William D.; Linn, Steven H.; Brown, Tanner W.; Goldberg, Jackson L.; Gomez, Aaron T.; Ronquillo, Yasmyne C.; Hoopes, Jr., Phillip C. title: Corneal Refractive Surgery in Patients with History of Optic Neuritis date: 2019-10-24 words: 3300 flesch: 54 summary: Majid Moshirfar: https://orcid.org/0000-0003-1024-6250 Abstract Purpose: The purpose of this study was to evaluate the risk of recurrence of optic neuritis after corneal refractive surgery in patients with a history of optic neuritis and to examine the safety and efficacy of the procedure in this population. Methods: This was a retrospective chart review of patients with a history of optic neuritis who underwent laser-assisted in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) at a single tertiary center from June 1996 to December 2014. keywords: 20/20; lasik; neuritis; optic; patients; prk; recurrence; study; surgery cache: jovr-5445.pdf plain text: jovr-5445.txt item: #119 of 284 id: jovr-5447 author: Prakash Guliani, Brahm ; Agarwal, Isha; Naik, Mayuresh P. title: Effect of Uncomplicated Cataract Surgery on Central Macular Thickness in Diabetic and Non-diabetic Subjects date: 2019-10-24 words: 3487 flesch: 48 summary: While others have reported that the development of postoperative macular edema does not need pre-existing DME,[11] these were published before the availability of optical coher- ence tomography (OCT) technology. In a case-control study conducted on around 4,500 diabetics without preoperative macular edema, the incidence of postoperative macular edema was 4%, which was higher than that in the population JOURNAL OF OPHTHALMIC AND VISION RESEARCH Volume 14, Issue 4, October-December 2019 445 Cataract Surgery and CMT; Guliani et al without diabetes (P < keywords: cataract; cmt; diabetic; edema; group; macular; postoperative; study; surgery cache: jovr-5447.pdf plain text: jovr-5447.txt item: #120 of 284 id: jovr-5451 author: Farvardin, Majid; Reza Khalili, Mohammad ; Behnia, Mehdi title: Levodopa Plus Occlusion Therapy versus Occlusion Therapy Alone for Children with Anisometropic Amblyopia date: 2019-10-24 words: 4421 flesch: 52 summary: Many patients with successfully treated amblyopia are known to exhibit a regression of visual acuity once stan- dard occlusion therapy is terminated.[2] Long-term follow-up of levodopa treatment in children with amblyopia has shown that the regression of visual acuity in patients receiving levodopa therapy alone was more (2.1 lines) than that in those receiving levodopa plus occlusion (1.4 lines).[11] Visual acuities of patients in the placebo and levodopa groups at each examination Group Baseline mean ± SD logMAR VA Three-week mean ± SD logMAR VA Fifteen-week mean ± SD logMAR VA Placebo group 0.425 ± 0.231 0.234 ± 0.096 0.271 keywords: amblyopia; anisometropic; children; groups; levodopa; occlusion; patients; study; therapy; treatment; visual cache: jovr-5451.pdf plain text: jovr-5451.txt item: #121 of 284 id: jovr-5453 author: Rajavi, Zhale; Feizi, Mohadeseh; Aliasghar Nabavi, Sayed ; Sabbaghi, Hamideh; Behradfar, Narges; Yaseri, Mehdi; Faghihi, Mohammad; Abdi, Saeid title: Slanted versus Augmented Recession for Horizontal Strabismus date: 2019-10-24 words: 5358 flesch: 54 summary: The mean slant for the esotropia, exotropia, and augmented recession groups was 2.38 ± 1.33 mm, 1.48 ± 0.79 mm, and 1.00–1.50 mm, respectively. Patients were randomly assigned into the slanted (n = 26 in ET and n = 24 in XT group) and augmented recession groups (n = 25 in ET and n = 25 in XT group). keywords: deviation; difference; distance; patients; recession; slanted cache: jovr-5453.pdf plain text: jovr-5453.txt item: #122 of 284 id: jovr-5455 author: Hashemi, Hassan; Saatchi, Mohammad; Yekta, Abbasali; Ali, Babak; Ostadimoghaddam, Hadi; Nabovati, Payam; Aghamirsalim, Mohamadreza; Khabazkhoob, Mehdi title: High Prevalence of Asthenopia among a Population of University Students date: 2019-10-24 words: 4624 flesch: 49 summary: Kotegawa Y, Hara N, Ono K, Arimoto A, Mukuno K. [Influ- ence of accommodative response and visual symptoms on visual display terminal adult operators with asthenopia through adequately corrected refractive errors]. Demographic factors and visual system disorders are important risk factors and timely correction of conditions may lead to decreased asthenopia. keywords: age; asthenopia; eye; prevalence; students; studies; study; symptoms; university; vision; years cache: jovr-5455.pdf plain text: jovr-5455.txt item: #123 of 284 id: jovr-5457 author: Hassanzadeh, Samira; Karimi Moonaghi, Hossein ; Derakhshan, Akbar; Masoud Hosseini, Seyed ; Taghipour, Ali title: Preferred Learning Styles among Ophthalmology Residents: An Iranian Sample date: 2019-10-24 words: 4223 flesch: 52 summary: Distribution of Kolb’s learning styles (in %) according to the year of residency Assimilative Convergent Accommodative Divergent 1st year 50.0 20.0 20.0 10.0 2nd year 61.5 38.5 0.0 0.0 3th year 50.0 50.0 0.0 0.0 4th year 41.7 41.7 8.3 8.3 486 JOURNAL OF OPHTHALMIC AND VISION RESEARCH Volume 14, Issue 4, October-December 2019 Learning Styles among Ophthalmology Residents; Hassanzadeh et al Figure 3. Distribution of VARK learning styles (in %) according to the year of residency Auditory Multimodal Visual Read & Write Kinesthetic 1st year 50.0 30.0 0.0 10.0 10.0 2nd year 23.0 38.5 15.4 15.4 7.7 3th year 37.5 12.5 37.5 0.0 12.5 4th year 33.3 33.3 25.0 8.4 0.0 the questionnaire has been examined in a few Western societies.[12] A review study carried out by Hashemi and his colleagues in 2014 showed a higher cataract surgery complication rate by Iranian ophthalmol- ogy residents as compared to their counterparts from other countries.[38] Phacoemulsification is one of the most common cataract procedures per- formed by ophthalmology residents. keywords: kolb; learners; learning; learning styles; mashhad; medical; ophthalmology; residents; sciences; students; styles; vark cache: jovr-5457.pdf plain text: jovr-5457.txt item: #124 of 284 id: jovr-5459 author: Amir Mishan, Mohammad ; Rezaei Kanavi, Mozhgan ; Shahpasand, Koorosh; Ahmadieh, Hamid title: Pathogenic Tau Protein Species: Promising Therapeutic Targets for Ocular Neurodegenerative Diseases date: 2019-10-24 words: 11204 flesch: 55 summary: AT8 tau protein was also detected with Aβ depositions in various retinal layers including the RGC layer, IPL, INL, outer plexiform layer (OPL), and outer nuclear layer (ONL) in Tg2576 mice.[154] Photoreceptor cells have high energy demands and are significantly affected by ageing.[155, 156] Although phosphorylation is an essential tau modifier under physiological conditions,[1] abnormal phosphoryla- tion or hyperphosphorylation are other modifiers by which tau gets prone to aggregation.[42, 43] For instance, hyperphosphorylated tau forms the oligomers and neurofibrillary tangles (NFTs) that exert toxic effects on neuronal function and AD progression.[44] Although 15–30 phosphorylation sites, that mostly corresponded to proline-directed sites in the proline-rich domain of tau were discov- ered in tau protein,[45] increased phosphorylation, especially at the MT-binding domains, has also been demonstrated in association with increased MT dynamicity and reduced levels of neuronal excitability in the early stages of AD.[46] Threonine175 (Thr175) is one of the important phosphorylation sites in tau protein that was first identified in AD[47] and then in amyotrophic lateral sclerosis (ALS) with cognitive impairment (ALSci).[48–52] keywords: aggregation; alzheimer; binding; biol; brain; cell; disease; domain; et al; human; isoforms; mice; microtubule; mishan; neurodegeneration; neuronal; neurosci; ocular; oligomers; ophthalmic; pathogenic; patients; phosphorylation; research; retina; role; tau; tau aggregation; tau isoforms; tau protein; tauopathy; transgenic; vision cache: jovr-5459.pdf plain text: jovr-5459.txt item: #125 of 284 id: jovr-5461 author: Yangzes, Sonam; Chawla Gupta, Parul ; Jha, Vivek; Ram, Jagat title: Pigmented Corneal Ulcer date: 2019-10-24 words: 1178 flesch: 49 summary: Vivek Jha, MS; Jagat Ram, MS, FAMS Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India ORCID: Sonam Yangzes: https://orcid.org/0000-0002-1862-0254 Jagat Ram: https://orcid.org/0000-00016251-2800 Abstract Purpose: To report the clinical characteristics, laboratory findings, and treatment of a rare case of keratitis caused by pigmented fungi Bipolaris hawaiiensis. 7. Anandi V, Suryawanshi NB, Koshi G, Padhye AA, Ajello L. Corneal ulcer caused by Bipolaris hawaiiensis. keywords: bipolaris; case; fungal; keratitis; ulcer cache: jovr-5461.pdf plain text: jovr-5461.txt item: #126 of 284 id: jovr-5463 author: Reena, Sharma; Mani, Krishna; Brahma Deo, Sharma ; Asma, Khan title: Ulcerative Squamous Eyelid Papilloma: A Rare Presentation date: 2019-10-24 words: 1390 flesch: 48 summary: The patient was diagnosed with squamous cell papilloma. Squa- mous cell papilloma is the most common benign lesion of the eyelid, constituting 13–19.5% of benign eyelid tumors.[3, 4] For squamous cell papilloma, having surface ulceration and indurated margins is not unusual. keywords: case; cell; eyelid; papilloma; patient cache: jovr-5463.pdf plain text: jovr-5463.txt item: #127 of 284 id: jovr-5471 author: Madanagopalan, V G; Velis, Girish title: A Unique Case of Bilateral Valsalva Retinopathy date: 2019-10-24 words: 885 flesch: 49 summary: Nd:YAG laser treatment for Valsalva premacular hemorrhages: 6 month follow up: alternative management options for preretinal premacular hemorrhages in Valsalva retinopathy. Turco CD, La Spina C, Mantovani E, Gagliardi M, Lattanzio R, Pierro L. Natural history of premacular hemorrhage due to severe acute anemia: clinical and anatomical features in two untreated patients. keywords: eye; hemorrhages; retinopathy; valsalva cache: jovr-5471.pdf plain text: jovr-5471.txt item: #128 of 284 id: jovr-5473 author: Shah, Tirth J.; Moshirfar, Majid; Hoopes, Phillip C. title: Safety of the Excimer Laser in LASIK and PRK for Patients with Implantable Cardiac Devices: Our Clinical Experience in the Past Two Decades date: 2019-10-24 words: 1111 flesch: 44 summary: Letter Safety of the Excimer Laser in LASIK and PRK for Patients with Implantable Cardiac Devices: Our Clinical Experience in the Past Two Decades Tirth J. Shah1,2, MD; Majid Moshirfar3,4,5, MD, FACS; Phillip C. Hoopes, Sr3,4, MD 1College of Medicine, University of Arizona, Phoenix, Arizona, USA 2Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, Iowa 3John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA 4HDR Research Center, Hoopes Vision, Draper, UT, USA 5Utah Lions Eye Bank, Murray, UT, USA ORCID: Tirth J. Shah: https://orcid.org/0000-0001-7924-8444 J Ophthalmic Vis Res 2019; 14 (4): 530–531 Sir, Continued high prevalence in cardiac morbidity in the US has led to more refractive surgical candi- dates with cardiac implantable electronic devices (CIED), although the Food and Drug Adminis- tration (FDA) studies have consistently excluded such populations during laser-assisted in situ ker- atomileusis (LASIK) or photorefractive keratectomy (PRK) evaluations. 4. Sher AN, Golben MP, Kresge K, Selznick L, Adabag S. An in vitro evaluation of electromagnetic interference between implantable cardiac devices and ophthalmic laser systems. keywords: devices; interference; laser; patients; surgery cache: jovr-5473.pdf plain text: jovr-5473.txt item: #129 of 284 id: jovr-5475 author: Aghsaei Fard, Masoud title: Idiopathic Intracranial Hypertension with Normal Cerebrospinal Fluid Pressure date: 2019-10-24 words: 728 flesch: 48 summary: 5. SAJJADI F, MH Khoshnevisan, JF Doane, Sajjadi H. New predictive value of optical coherence tomography analysis in the diagnosis of idiopathic intracranial hypertension. Another study also considered cerebrospinal fluid measures ≤ 28 cm H2O as ”normal” for most children.[3] The two case reports that the authors cited with normal cerebrospinal fluid pressure had other features of idiopathic intracranial hyperten- sion such as papilledema, headache, and pulsatile tinnitus.[4] 2. keywords: hypertension; pressure cache: jovr-5475.pdf plain text: jovr-5475.txt item: #130 of 284 id: jovr-5477 author: Sajjadi, Hamid; Poorsalman, Hossein title: Author’s Reply date: 2019-10-24 words: 754 flesch: 60 summary: There are lots of cases of optic atrophy with unknown cause and there should be a way to explain their origin. The ICP that was measured in our case was 18 cmH2O in lateral decubitus position which used to be high before 2016; however, it has been challenged in recent articles that in children it can be up to 26 cmH2O. keywords: optic; patient; sajjadi cache: jovr-5477.pdf plain text: jovr-5477.txt item: #131 of 284 id: jovr-5479 author: Dhahir Al-Mendalawi, Mahmood title: Primary Atypical Lipomatous Tumor of the Orbit date: 2019-10-24 words: 523 flesch: 53 summary: Among these tumors, liposarcomas have been reported in HIV-positive patients.[3, 4] To my knowledge, HIV infection is a distressing health threat in the United States of America (USA). According to the available data, an estimated 1.1 million people aged ≥ 13 years were living with HIV infection in the USA at the end of 2015, including an estimated 162,500 (15%) persons with undiagnosed infections.[5] keywords: hiv; infection cache: jovr-5479.pdf plain text: jovr-5479.txt item: #132 of 284 id: jovr-5930 author: Elahi, Elahe title: Genetic Basis of Primary Angle Closure Glaucoma: The Role of Collagens and Extracellular Matrix date: 2020-02-03 words: 2068 flesch: 62 summary: ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. Khor CC, Do T, Jia H, Nakano M, George R, Abu-Amero K, et al. Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. keywords: angle; closure; gene; glaucoma; mol; pacg cache: jovr-5930.pdf plain text: jovr-5930.txt item: #133 of 284 id: jovr-5934 author: Mohammad Salar Zaheryani, Seyed ; Bamdad, Shahram; Mohaghegh, Sahar; Shirvani, Mohammad title: Fourier Analysis of Keratometric Data in Epithelium Removal versus Epithelial Disruption Corneal Cross-linking date: 2020-02-03 words: 4676 flesch: 41 summary: Our findings revealed that although epithelium removal CXL is more aggressive, it does not lead to better short- term follow-up results. We made a comparison between our results and those of previous studies that had compared epithelium removal CXL with other CXL modifications [Table 3]. keywords: analysis; corneal; cxl; disruption; epithelium; fourier; keratoconus; removal; results cache: jovr-5934.pdf plain text: jovr-5934.txt item: #134 of 284 id: jovr-5936 author: Salouti, Ramin; Bagheri, Mansoureh; Shamsi, Anis; Zamani, Mohammad; Ghoreyshi, Maryam; Nowroozzadeh, M. Hossein title: Corneal Parameters in Healthy Subjects Assessed by Corvis ST date: 2020-02-03 words: 3987 flesch: 50 summary: To accomplish this, Corvis ST cap- tures a series of horizontal Scheimpflug images using a high-speed camera that gathers 4,300 frames per sec within a 100 milliseconds (ms) period.[1, 5] Currently, there are few reports regarding the normal distribution of Corvis ST parameters from different populations.[1, 6–10] Table 6 presents the normal values of Corvis ST parameters, stratified based on the corresponding IOP. keywords: applanation; corneal; corvis; eyes; iop; mean; parameters cache: jovr-5936.pdf plain text: jovr-5936.txt item: #135 of 284 id: jovr-5938 author: Singh Parmar, Gautam ; Ghodke, Bhushan; Kumar Meena, Ashok title: Releasable Suture versus Autologous Blood for Pterygium Surgery using Conjunctival Autografts date: 2020-02-03 words: 3485 flesch: 60 summary: Conclusion: RS, by augmenting the autologous blood mechanism, may offer an easy to learn option for pterygium surgery with good stability even in large sized CAGs. Both techniques were equally effective in lowering the recurrence rate after pterygium surgery. keywords: cag; conjunctival; graft; group; patients; pterygium; surgery; suture cache: jovr-5938.pdf plain text: jovr-5938.txt item: #136 of 284 id: jovr-5940 author: Yaghoobi, Ghalam-Hosein; Shokoohi-Rad, Saeed ; Jafarzadeh, Hamid; Abodollahi, Elham title: Serum Fibroblast Growth Factor 21 in Patients with and without Pterygia date: 2020-02-03 words: 4060 flesch: 56 summary: Moreover, regarding the comparison of serum FGF21 in pterygium patients in terms of gender, 40 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 1, JANUARY-MARCH 2020 Serum FGF 21 Levels in Patients with Pterygia; Yaghoobi et al Table 3. This study took into account the probability of such metabolic changes in pterygium patients. keywords: diabetes; factor; fgf21; levels; patients; pterygium; serum; study; type cache: jovr-5940.pdf plain text: jovr-5940.txt item: #137 of 284 id: jovr-5942 author: Yousefian, Ali; Shokoohi-Rad, Saeed ; Reza Abbaszadegan, Mohammad ; Morshedi Rad, Dorsa ; Zargari, Selma; Milanizadeh, Saman; Morovatdar, Negar; Daneshvar, Ramin title: Primary Angle Closure Glaucoma-associated Genetic Polymorphisms in Northeast Iran date: 2020-02-03 words: 3713 flesch: 51 summary: BY KNOWLEDGE E 45 http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v15i1.5942&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR PACG Genetic Polymorphisms; Yousefian et al are affected and it is predicted that by 2020, this number will rise to around 79.6 million – – rs3739821 0.42 T/T Male 12(23) 5(10) Reference Reference T/C 28(53) 31(61) 0.4(0.1–1.5) 0.19 C/C 13(24) 15(29) 0.3(0.1–1.3) 0.11 T/T Female 16(21) 18(23) Reference Reference T/C 15(66) 45(57) 1(0.4–2.6) 0.83 C/C 10(13) 16(20) 0.7(0.2–2.4) 0.66 rs7494379 < 0.001 C/C Male 16(31) 32(63) Reference Reference C/T 22(41) 14(27) 2.6(0.9–7.4) 0.063 T/T 15(75) 5(10) 8.4(2.2–32.1) 0.002 C/C Female 32(42) 48(61) Reference Reference C/T 28(36) 23(29) 1.6(0.7–3.5) 0.2 T/T 17(22) 7(10) 3(1–8.8) 0.04 50 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 1, JANUARY-MARCH 2020 PACG Genetic Polymorphisms; Yousefian et al into risk categories would allow tailored screening, prognosis, and treatment programs according to the risk of each individual. keywords: angle; association; closure; gene; genotype; glaucoma; pacg; polymorphisms; reference; reference reference cache: jovr-5942.pdf plain text: jovr-5942.txt item: #138 of 284 id: jovr-5944 author: Hedayatfar, Alireza; Ashraf Khorasani, Maryam ; Behnia, Mehdi; Sed-aghat, Ahad title: Seasonality of Acute Retinal Necrosis date: 2020-02-03 words: 3065 flesch: 56 summary: Demographics, causative viral agent(s), and date of disease onset in ARN cases Patient # PCR result Gender Age at onset (years) The patient with bilateral ARN did not consent for bilateral sampling, therefore, only the eye with more extensive involvement was sampled (positive 54 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 1, JANUARY-MARCH 2020 WorldWeatherOnline.com Seasonality of ARN; Hedayatfar et al Table 1. keywords: acute; arn; incidence; necrosis; ophthalmol; patients; study; temperature; vzv cache: jovr-5944.pdf plain text: jovr-5944.txt item: #139 of 284 id: jovr-5946 author: Nikkhah, Homayoun; Feizi, Mohadeseh; Abedi, Naser; Karimi, Saeed; Yaseri, Mehdi; Esfandiari, Hamed title: Choroidal Thickness in Acute Non-arteritic Anterior Ischemic Optic Neuropathy date: 2020-02-03 words: 5681 flesch: 55 summary: Diff (1 vs 3) P2* Diff (2 vs 3) P3* Mean ± SD Mean ± SD Mean ± SD PCT S 1000 173.2 ± 59.4 164.9 ± 47.4 135.7 ± 57.3 8.2 1.000 37.4 0.007 29.2 0.065 PCT I 1000 151.2 ± 62.4 131.5 ± 47.5 112.2 ± 51.7 19.7 0.076 39.0 0.012 19.3 0.112 PCT T 1000 181.5 ± 69.9 167.9 ± 53.9 131.8 ± 58.7 13.7 0.429 49.7 0.001 36.1 0.043 PCT N 1000 172.8 ± 61.9 153.5 ± 52.2 131.2 ± 54.9 19.3 0.027 41.6 0.005 22.3 0.221 Mean PCT 1000 169.7 ± 47 154.4 ± 42.1 127.7 ± 49.9 15.2 0.027 41.9 < 0.001 26.7 0.042 PCT S 1500 175.3 ± 69.6 165.5 ± 51.3 141.2 ± 69.4 9.8 1.000 34.0 0.054 24.3 0.287 PCT I 1500 155.5 ± 71.4 132.7 ± 47.4 113.8 ± 62.5 22.8 0.059 41.7 0.015 18.9 0.395 PCT T 1500 208.7 ± 80.6 190.5 ± 67.7 144.9 ± 64.7 18.3 0.301 63.9 < 0.001 45.6 0.012 PCT N 1500 172.7 ± 64.1 161.7 ± 55.6 140.5 ± 64 11.0 0.314 32.2 0.073 21.2 0.442 Mean PCT 1500 178.6 ± 52.8 162.6 ± 46.1 135.1 ± 59 16.0 0.035 43.5 0.007 27.5 0.048 PCT, peri-papillary choroidal thickness; NAION, non-arteritic anterior ischemic optic neuropathy; S, superior; I, inferior; T, temporal; N, nasal; 1000, at 1000micron from Bruch’s membrane opening; 1500, at 1500micron from Bruch’s membrane opening; SD, standard deviation; Diff, difference * P-for pairwise comparison, based on post hoc analysis of GEE, adjusted for the multiple comparison by Bonferroni method Table 4. Measurements of GC-IPL, RFNL, SFCT and CMT in different areas in study groups (NAION, uninvolved, and control eyes) NAION eyes Uninvolved eyes Control eyes Diff (NAION vs Uninvolved eyes) Choroidal thickness among NAION eyes, uninvolved fellow eyes, and control eyes were compared. keywords: control; control eyes; eyes; fellow; ischemic; mean; naion; neuropathy; optic; pct; thickness cache: jovr-5946.pdf plain text: jovr-5946.txt item: #140 of 284 id: jovr-5950 author: Karimi, Saeed; Arabi, Amir; Shahraki, Toktam; Safi, Sare title: Von Hippel-Lindau Disease and the Eye date: 2020-02-03 words: 11624 flesch: 49 summary: However, it is now believed that partial deletion, missense, and nonsense mutations are correlated with higher prevalence of RHs and worse visual prognosis, unlike complete deletion of the VHL gene.[35, 36] Additionally, the location of a missense mutation in VHL correlates with the phenotype of ocular VHL disease, and mutations 80 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 1, JANUARY-MARCH 2020 However, to justify the burden of the disease, it was reported that approximately 20% of all patients with ocular VHL disease had at least some degree of unilateral visual impairment. keywords: cases; diagnosis; disease; et al; eyes; gene; growth; hemangioma; juxtapapillary; laser; lesions; lindau disease; ophthalmol; patients; photocoagulation; research; retina; rhs; study; therapy; treatment; tumor; vascular; vhl; vhl disease; vision; von hippel cache: jovr-5950.pdf plain text: jovr-5950.txt item: #141 of 284 id: jovr-5952 author: Farvardin, Majid; Bolkheir, Alireza title: Unilateral Duane Retraction Syndrome Associated with Unilateral Congenital Cataract date: 2020-02-03 words: 1932 flesch: 43 summary: She was finally diagnosed as having Duane retraction syndrome in the same eye. Conclusion: Duane retraction syndrome can be associated with congenital cataract due to the matching time of gestational development of the lens to that of ocular and non- ocular anomalies associated with Duane syndrome. keywords: cataract; duane; eye; retraction; syndrome cache: jovr-5952.pdf plain text: jovr-5952.txt item: #142 of 284 id: jovr-5962 author: A. Rezaei, Kasra ; Vangipuarm, Gautam; S. Saraf, Steven ; Zhang, Qinqin; Wang, Ruikang title: Profound Presentation of Retinopathy in a Patient with Sickle Cell trait and Diabetes Mellitus date: 2020-02-03 words: 749 flesch: 41 summary: A broad differential must be maintained in patients with presumed diabetic retinopathy, especially those with uncharacteristic imaging findings.[1–5] Financial Support and Sponsorship This study was supported by the Department of Ophthalmology, University of Washington. 5. Nagpal KC, Asdourian GK, Patrianakos D, Goldberg MF, Rabb MF, Goldbaum M. Proliferative retinopathy in SCT. keywords: negative; retinopathy cache: jovr-5962.pdf plain text: jovr-5962.txt item: #143 of 284 id: jovr-5963 author: Srirampur, Arjun; Balijepalli, Pasyanthi title: Multiple Pit Defects in a Foldable Hydrophobic Intraocular Lens date: 2020-02-03 words: 610 flesch: 36 summary: Prolonged breakdown of the blood-aqueous barrier has been suggested as a contributory factor in IOL pit formation. 4. Dhittal A, Spalton DJ, Goyal S, Werner L. Calcification in hydrophilic intraocular lenses associated with injection of intraocular gas. keywords: lens; pit cache: jovr-5963.pdf plain text: jovr-5963.txt item: #144 of 284 id: jovr-5964 author: Gatzioufas, Zisis; Elalfy, Mohamed; Hamada, Samer title: Author's Reply to Multiple Pit Defects in a Foldable Hydrophobic Intraocular Lens date: 2020-02-03 words: 275 flesch: 45 summary: Correspondence to: Zisis Gatzioufas MD, PhD. Corneo-Plastic Unit, Queen Victoria Hospital, Holtye Rd, East Grinstead RH19 3DZ, United Kingdom. However, we reported a case of hydropho- bic intraocular lens opacification after penetrating keratoplasty, and to the best of our knowledge, this was the first time that this type of intraoc- ular lens opacification occurred. keywords: lens cache: jovr-5964.pdf plain text: jovr-5964.txt item: #145 of 284 id: jovr-5965 author: Dhahir Al-Mendalawi, Mahmood title: Optic Nerve Cysticercosis at the Orbital Apex date: 2020-02-03 words: 516 flesch: 48 summary: Among parasitic infections, cysticercosis has been reported among HIV-positive patients.[2] To my knowledge, HIV infection is a distressing health issue in India. Accordingly, planning for the diagnostic battery of blood CD4 count and viral overload measurements for HIV infection was envisaged. keywords: cysticercosis; hiv cache: jovr-5965.pdf plain text: jovr-5965.txt item: #146 of 284 id: jovr-5967 author: Goel, Neha title: Author's Reply to Optic Nerve Cysticercosis at the Orbital Apex date: 2020-02-03 words: 151 flesch: 49 summary: J Ophthalmic Vis Res 2020;15:122–122. Letter Author’s Reply Neha Goel, MS, DNB, FRCS (Glasg) ICARE Eye Hospital and Postgraduate Institute, Noida, Uttar Pradesh, India ORCID: Neha Goel: https://orcid.org/xxx J Ophthalmic Vis Res 2020; 15 (1): 122–122 I thank Dr. Mahmood Dhahir Al-Mendalawi for his interest in our article and his comments. keywords: goel cache: jovr-5967.pdf plain text: jovr-5967.txt item: #147 of 284 id: jovr-5968 author: Gharebaghi, Reza; Heidary, Fatemeh title: Prevalence of Visual Impairment in School Children date: 2020-02-03 words: 715 flesch: 48 summary: Firstly, we included 262 eyes of Iranian primary school children in Shiraz between 6 and 13 years of age and found that intraocular pressure (IOP) and central corneal thickness (CCT) in healthy school children were positively correlated.[2] The Shiraz Pediatric Eye Study; a population based survey of school age children: rationale, design and base- line characteristics. keywords: children; ophthalmic; school cache: jovr-5968.pdf plain text: jovr-5968.txt item: #148 of 284 id: jovr-5970 author: Reza Talebnejad, Mohammad ; Hossein Nowroozzadeh, Mohammad ; Mahdaviazad, Hamideh title: Author’s Reply to Prevalence of Visual Impairment in School Children date: 2020-02-03 words: 460 flesch: 45 summary: Letter Author’s Reply Mohammad Reza Talebnejad1, MD; M. Hossein Nowroozzadeh1, MD; Hamideh Mahdaviazad1,2, MD 1Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 2Department of Family Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ORCID: The Shiraz Pediatric Eye Study; a population based survey of school age children: rationale, design and baseline characteristics. keywords: shiraz; study cache: jovr-5970.pdf plain text: jovr-5970.txt item: #149 of 284 id: jovr-5971 author: Tadayoni, Ramin title: Time to Call into Question the Fundus-based Evaluation of Diabetic Retinopathy after Intravitreal Injections date: 2020-02-03 words: 1668 flesch: 50 summary: Data on DR evolution after anti-VEGF treatment are limited but the reported series tend to sug- gest that anti-VEGF intravitreal injections clear the fundus from hemorrhages and signs of vessel impregnation with VEGF without eliminating the risks of neovascularization shortly after treatment discontinuation.[5] In the second study, using a similar method but based on wide-field OCT angiography, we found that despite a rapid DRSS score improvement after anti-VEGF treatment, no reperfusion occurred, including at the capillary level.[7] keywords: fundus; retinopathy; vegf cache: jovr-5971.pdf plain text: jovr-5971.txt item: #150 of 284 id: jovr-6728 author: Farazdaghi, Mahmood title: World’s Largest Eye Bank has Served a Nation for Three Decades date: 2020-04-06 words: 1068 flesch: 49 summary: During 2018, US eye banks provided 85,441 transplantable corneas, out of which 51,294 were distributed domestically and 27,913 internationally.[2] With US population of 327.2 million per capita, the availability of transplant is 261 while per capita transplant is 156.8. Thus, providing a trans- plantable rate of 83.5%, which is again by far the highest amongst other eye banks. keywords: bank; corneas; eye; transplant cache: jovr-6728.pdf plain text: jovr-6728.txt item: #151 of 284 id: jovr-6729 author: Puig, Madeleine; Weiss, Menachem; Salinas, Ricardo; A Johnson, Daniel ; Kheirkhah, Ahmad title: Etiology and Risk Factors for Infectious Keratitis in South Texas date: 2020-04-06 words: 5425 flesch: 52 summary: Rate of infectious keratitis in South Texas compared with other locations % of culture-proven cases % of bacterial cases from total positive cultures % of fungal cases from total positive cultures % of Acanthamoeba cases from total positive cultures South Texas 53.6% 95.1% 6.9% 1.6% DEI-LA[17] 63% 89.8% 9.8% 0.4% LAC + Spectrum of bacterial isolates observed in cases with bacterial keratitis in South Texas Bacteria Number of cases Percentage of Bacterial Isolates Coagulase-negative Staphylococcus 56 25.7% Pseudomonas aeruginosa 51 23.4% Staphylococcus aureus 24 11.0% Moraxella species 17 7.8% Propionibacterium acnes 9 4.1% Streptococcus viridans 8 3.7% Diphtheroids 8 3.7% Bacillus species 6 2.8% Streptococcus pneumoniae 6 2.8% keywords: bacterial; cases; contact; factors; fungal; keratitis; lens; patients; risk; south; study; texas; years cache: jovr-6729.pdf plain text: jovr-6729.txt item: #152 of 284 id: jovr-6731 author: Ali Javadi, Mohammad ; Rezaei Kanavi, Mozhgan ; Safi, Sare title: A 27-Year Report from the Central Eye Bank of Iran: A complete translation from Farsi date: 2020-04-06 words: 6010 flesch: 55 summary: This probably reflects the CEBI’s ability to immediately supply corneal tissues according to the nation’s demands. There has been an increasing trend for new transplantation techniques such as KLAL, GSC using corneal tissue, and DMEK since their intro- duction in Iran. keywords: bank; corneal; endothelial; eye; graft; indications; iran; keratoplasty; rate; report; transplantation; trend; years cache: jovr-6731.pdf plain text: jovr-6731.txt item: #153 of 284 id: jovr-6732 author: Moradian, Siamak; Ebrahimi, Marzieh; Kanaani, Azade; Faramarzi, Amir; Safi, Sare title: Topical Umbilical Cord Serum for Corneal Epithelial Defects after Diabetic Vitrectomy date: 2020-04-06 words: 3424 flesch: 55 summary: https://orcid.org/0000-0002-5328-7565 Abstract Purpose: To evaluate the role of topical umbilical cord serum (TUCS) therapy in treating corneal epithelial defects (CEDs) after diabetic vitrectomy. CED, corneal epithelial defect; F, female; M, male; SD, standard deviation Table 2. keywords: ced; cord; corneal; epithelial; eye; ophthalmol; patients; serum; tucs; vitrectomy cache: jovr-6732.pdf plain text: jovr-6732.txt item: #154 of 284 id: jovr-6733 author: Akhlaghi, Mohammadreza; Zarei, Masoomeh; Ziaei, Majid; Pourazizi, Mohsen title: Sensitivity, Specificity and Accuracy of Color Doppler Ultrasonography for Diagnosis of Retinal Detachment date: 2020-04-06 words: 2860 flesch: 49 summary: In their study, all patients with blood flow on CDUS were confirmed to have RD during surgery.[10] In the study by Han et al, CDUS showed a color signal in approximately 60% of RD cases.[8] Wong et al reported the sensitivity of CDUS to be 100%.[17] The sensitivity and specificity of ocular CDUS were both approximately 90% in our study. Methods: In this prospective, observational clinical study, 65 eyes of 65 consecutive patients with suspected RD with opaque media were included. keywords: cdus; color; diagnosis; doppler; patients; study; ultrasonography cache: jovr-6733.pdf plain text: jovr-6733.txt item: #155 of 284 id: jovr-6734 author: Afarid, Mehrdad; Ghattavi, Naghme; Karim Johari, Mohammad title: Serum Levels of Vitamin D in Diabetic Patients With and Without Retinopathy date: 2020-04-06 words: 3509 flesch: 57 summary: On the contrary, some studies found no differences in serum vitamin D levels between diabetic patients with and without retinopathy.[16, 18] Evidence shows that vitamin D may affect the pathogenesis of DR via its effects on angio- genesis by changing the presence of hypoxia- inducible products, such as vascular endothelial growth factor (VEGF).[9] Ben-Shoshan et al found that 1, 25 (OH)2D3 decreases the protein expres- sion of both regulated hypoxia-inducible factor (HIF)-1α subunit and the VEGF in human cancer cells.[21] Vitamin D reduces inflammatory prod- ucts by decreasing the lymphocyte proliferation and cytokine production.[22] Vitamin D deficiency was defined as a serum 25 (OH) keywords: diabetes; levels; mean; patients; retinopathy; serum; study; vitamin; vitamin d cache: jovr-6734.pdf plain text: jovr-6734.txt item: #156 of 284 id: jovr-6735 author: M. Zereid, Feryal ; L. Osuagwu, Uchechukwu title: Myopia and Regional Variations in Retinal Thickness in Healthy Eyes date: 2020-04-06 words: 5229 flesch: 51 summary: The enlarged globe and the elongated axial length of the myopic eyes lead to an ocular dimension that is stretched beyond its normal limit, which may lead to retinal thinning.[12, 13] Ocular conditions such as glaucoma, which are prevalent among individuals with highly myopic eyes, may also significantly affect the thickness of the inner retinal layers.[12, 13] Optical coherence tomography (OCT) offers a modern technique for in vivo measurements of reti- nal thickness and enables the assessment of the relationship between myopia and retinal thickness. Although studies have investigated the changes in retinal thickness in other populations,[17–28] they have considered only the central retinal region or recruited individuals with high or pathologic myopia,[17, 27] and the results have been inconclusive[17–28] due to the different methodologies used in the studies.[17–29] Retinal thickness measurements by OCT vary according to the population being studied;[30] thus, knowledge of such population-based differences in retinal thickness distribution is important in the evaluation, treatment, and follow-up of patients in a particular population and/or with various ocular pathologies.[17, 31] keywords: coherence; eyes; groups; locations; measurements; myopia; non; participants; refractive; study; thickness; tomography cache: jovr-6735.pdf plain text: jovr-6735.txt item: #157 of 284 id: jovr-6736 author: Venkatesh, Ramesh; Jain, Kushagra; Pereira, Arpitha; ., Thirumalesh; Kumar Yadav, Naresh title: Torpedo Retinopathy date: 2020-04-06 words: 4412 flesch: 60 summary: The differentials for torpedo lesions lying outside the retinal arcade were CHRPE and RPE lesions, observed in systemic disorders such as Gardner syndrome and JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 2, APRIL-JUNE 2020 189 Torpedo Retinopathy; Venkatesh et al Figure 2. Ramesh Venkatesh: https://orcid.org/0000-0002-4479-9390 Abstract Purpose: Torpedo lesions in the retina are rare. keywords: lesions; ni ng; torpedo cache: jovr-6736.pdf plain text: jovr-6736.txt item: #158 of 284 id: jovr-6737 author: Atum, Mahmut; Alagöz, Gürsoy title: Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Patients with RetinalArtery Occlusion date: 2020-04-06 words: 3382 flesch: 58 summary: Patients with high NLR levels are 3.8 times more likely to have RAO than patients with low NLR levels. Azab et al identified a relationship between increased PLR and long-term mortality in 198 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 2, APRIL-JUNE 2020 Blood Cell Ratios in Patients with RAO; Atum and Alagöz patients with myocardial infarction,[11] while Ferroni et al reported a relationship between increased PLR and the risk of venous thromboembolism.[22] In their review, Balta et al demonstrated that a high PLR level is associated with inflamma- tion, atherosclerosis, and activated platelets.[23] Our study showed that patients with RAO had higher PLRs than control subjects; however, logistic regression analysis showed that PLR cannot be used as an indicator of RAO. Şahin et al reported that MPV values were significantly higher in patients with RAO than in control subjects,[13] but we were unable to replicate this finding. keywords: control; lymphocyte; neutrophil; nlr; patients; platelet; plr; rao; ratio; subjects cache: jovr-6737.pdf plain text: jovr-6737.txt item: #159 of 284 id: jovr-6739 author: Singh, Kirti; Bhattacharyya, Mainak; Goel, Abhishek; Arora, Ritu; Gotmare, Nikhil; Aggarwal, Himshikha title: Orthokeratology in Moderate Myopia: A Study of Predictability and Safety date: 2020-04-06 words: 4417 flesch: 61 summary: The reversibility of the procedure within two to four weeks of discon- tinuation of OK lens wear is a consequence of regression of corneal parameters.[10] Common issues of concern with OK lens use include the unpredictability of visual gain due to issues of inadequate lens centration, poor con- trast with persistent use, and increase in higher- order aberrations (HOA) and safety because of the inherent risk of microbial keratitis.[11] In the OK group, cornea showed a flattening of 0.8 D (mean keratometry) after single overnight usage of OK lens and overall flattening of 1.2 D compared to baseline, at the end of four months. keywords: corneal; group; lens; lenses; myopia; orthokeratology; study; wear cache: jovr-6739.pdf plain text: jovr-6739.txt item: #160 of 284 id: jovr-6742 author: Takkar, Brijesh; Rathi, Anubha; Venkatesh, Pradeep; Kumar, Atul title: Giant Idiopathic Angioid Streaks date: 2020-04-06 words: 2463 flesch: 53 summary: Additionally, right eye has an area with peripheral retinal hemorrhages bounded by two peripheral streaks (encircled). Case Report: A young male presented with macular choroidal neovascular membrane (CNVM) and peripheral retinal hemorrhages secondary to angioid streaks. keywords: angioid; eye; figure; membrane; patient; peripheral; right; streaks cache: jovr-6742.pdf plain text: jovr-6742.txt item: #161 of 284 id: jovr-6744 author: K. Ndulue, Jideofor; Mashayekhi, Arman; L. Shields, Carol title: Ciliary Body Seeding after Pars Plana Transvitreal Fine-Needle Aspiration Biopsy of Choroidal Melanoma date: 2020-04-06 words: 2114 flesch: 52 summary: Based on these find- ings, a clinical diagnosis of ciliary body melanoma with anterior chamber invasion, angle seeding, and early extraocular extension was made. A serious potential complication of FNAB is extraocular tumor extension. keywords: body; ciliary; fnab; melanoma; needle; seeding; tumor cache: jovr-6744.pdf plain text: jovr-6744.txt item: #162 of 284 id: jovr-6745 author: Hassanpour, Kiana; Nourinia, Ramin; Behnaz, Nazanin; Azarmina, Mohsen; Jalali, Setareh; Roshandel, Danial title: Bilateral Keratoconus in a Patient with Isolated Foveal Hypoplasia date: 2020-04-06 words: 976 flesch: 47 summary: The manifest refraction was –3.00 –9.5 × 20° and –2.5 –9.00 × 150° in her right and left eyes, respectively. Spectral-domain optical coherence tomographic section through the center of the macular area of the right (A) and left (B) eyes. keywords: eyes; foveal; macular cache: jovr-6745.pdf plain text: jovr-6745.txt item: #163 of 284 id: jovr-6746 author: Murugan, Bala; Chawla Gupta, Parul ; Prakash Sharma, Surya ; Rana, Neeti; Ram, Jagat title: Microsporidial Keratoconjunctivitis date: 2020-04-06 words: 609 flesch: 42 summary: It has recently been observed to cause multifocal coarse punctate epithelial keratitis in immunocompromised individuals, In addition to the use of contact lenses, another risk factor for microsporidial keratoconjunctivitis that may be less recognized because of the lack of awareness among ophthalmologists is the exposure to muddy water[2, 3] predominantly observed during the rainy season[4] in developing countries. We report microsporidial keratoconjunctivitis in a young male exposed to muddy water while repair- ing a water distribution pipe successfully treated with topical voriconazole. keywords: figure; keratoconjunctivitis; microsporidial cache: jovr-6746.pdf plain text: jovr-6746.txt item: #164 of 284 id: jovr-6747 author: S. Nakatsuka, Austin ; Banaee, Touka; Loucks, Emma; El-Annan, Jaafar title: Simple Congenital Hamartoma of the Retinal Pigment Epithelium date: 2020-04-06 words: 904 flesch: 43 summary: Shukla D, Ambatkar S, Jethani J, Kim R. Optical coher- ence tomography in presumed congenital simple hamar- toma of retinal pigment epithelium. The absence of a history of trauma, retinal traction, time-related growth features, and the typical fun- duscopic features of the lesion can help differenti- ate between these diagnoses. keywords: hamartoma; rpe; texas cache: jovr-6747.pdf plain text: jovr-6747.txt item: #165 of 284 id: jovr-6749 author: Mimura, Tatsuya; Iida, Michiko; Noma, Hidetaka; Kondo, Aki; Yoshida, Maiko; Oguri, Manami; Tanaka, Yuka; Mizota, Atsushi title: Does Clear Cornea Cataract Surgery Influence Conjunctivochalasis? date: 2020-04-06 words: 1061 flesch: 46 summary: Letter to Editor Does Clear Corneal Cataract Surgery Influence Conjunctivochalasis? Tatsuya Mimura1,2,3, MD, PhD; Michiko Iida2, MD; Hidetaka Noma4, MD, PhD; Yuko Kamei2, MD Aki Kondo2,3, MD, PhD; Maiko Yoshida2,3, MD; Manami Oguri2, MD; Yuka Tanaka2, MD Atsushi Mizota1, MD, PhD 1Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan 2Department of Ophthalmology, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan 3Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan 4Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan ORCID: Tatsuya Mimura: https://orcid.org/0000-0001-5593-5338 J Ophthalmic Vis Res 2020; 15 (2): 270–272 Dear Editor, Conjunctivochalasis is a common ocular condition characterized by excess conjunctival folds and is associated with aging.[1–4] We previously demon- strated that the progression of conjunctivochalasis after sclerocorneal tunnel incisions was associated with the axial length of the eyeball and placement of conjunctival sutures.[4] Conjunctival chemosis occurs more frequently in cases of sclerocorneal tunnel incisions than in cases of corneal incisions.[5] Therefore, we evaluated the influence of clear corneal incision in cataract surgery on the severity of conjunctivochalasis based on a previously reported grading scale.[1] keywords: conjunctivochalasis; mimura; tokyo cache: jovr-6749.pdf plain text: jovr-6749.txt item: #166 of 284 id: jovr-7444 author: Zarbin, Marco title: The Development Pathway for Biosimilar Biotherapeutics date: 2020-07-29 words: 1240 flesch: 40 summary: Switching studies demonstrating interchangeability of biosimilars and reference products have not been required for marketing approval by the European Medicine Agency,[6] In contrast to generic drugs, biosimilars tend to have complex structures and may differ from the reference product in their primary amino acid sequence and other features such as glycosylation and PEGylation that alter their tertiary structure (i.e., protein folding) as well as their immunogenicity.[2] These differences arise from the manufacturing process, which tends to be much more complex than that of generic drugs. keywords: biosimilars; generic; product; reference cache: jovr-7444.pdf plain text: jovr-7444.txt item: #167 of 284 id: jovr-7445 author: Shahraz, Saeid; Farzad Mohammadi, Seyed ; Safi, Sare title: The role of Guidance and Planning on Safety of Ophthalmic Practice during the COVID-19 Pandemic date: 2020-07-29 words: 1857 flesch: 23 summary: We have to consciously monitor the pandemic status, public health developments, and the evidence which emerges to tailor and update our control measures and eye care strategies. The nasopharyngeal RT-PCR results were indicative of the presence of the virus in all patients with positive tear RT-PCR results, which comprised a case with clinical conjunctivitis.[11] Although the rate of ocular manifestations is low, protecting against viral transmission is vital in ophthalmology practice due to the proximity between the examiner and patients, the lengthy period of exposure during examinations, and direct contact with patient’s eye secretions.[12] Many non-urgent ophthalmic services were ceased at the ophthalmology centers in Iran, similar to other countries, during the early months of the pandemic to tackle the spread of COVID- 19. Government agencies, ophthalmology societies, and eye health centers have developed guidance and policy statements to reduce the risk of transmission on one hand and maintain continuity of eye care on the other.[13–19] keywords: care; covid-19; eye; guidance; health; ophthalmic; ophthalmology; pandemic cache: jovr-7445.pdf plain text: jovr-7445.txt item: #168 of 284 id: jovr-7446 author: Rodriguez-Garcia, Alejandro ; Alfaro-Rangel, Raul ; Bustamante-Arias, Andres ; C. Hernandez-Camarena , Julio title: In Vivo Corneal Microstructural Changes in Herpetic Stromal Keratitis: A Spectral-Domain Optical Coherence Tomography Analysis date: 2020-07-29 words: 5538 flesch: 45 summary: SD-OCT (RTVue-100®, Optovue, Inc., Fremont, CA, USA) analysis was performed by the same technician (SIS) to each eye using a corneal module adaptor (CAM) L-lens (15 µm) and S-lens (10 µm), depending on whether the full extent or the details of corneal lesions, respectively, were analyzed as requested in a drawing scheme. Corneal lesions consisting of inflammatory infiltrates and stromal edema from eyes with active keratitis and scars or leukomas from eyes with inactive disease were studied. keywords: analysis; corneal; edema; eyes; herpetic; hsk; inflammatory; keratitis; necrotizing; oct; stromal; stromal keratitis cache: jovr-7446.pdf plain text: jovr-7446.txt item: #169 of 284 id: jovr-7448 author: Yari, Davood; Ehsanbakhsh, Zohreh; Validad, Mohammad-Hosein; Hasanian Langroudi, Farzaneh title: Association of TIMP-1 and COL4A4 Gene Polymorphisms with Keratoconus in an Iranian Population date: 2020-07-29 words: 5498 flesch: 54 summary: We used modified methods of Nested-PCR and ARMS-PCR in combination (Nested- ARMS-PCR) and confirmed their validity with RFLP–PCR. Results: Significant differences were noticed between KC patients and healthy individuals regarding the genotype TY or T allele frequencies of rs4898 in the male subjects (OR = 0.43, 95%CI: 0.20–0.92, P = 0.03), whereas no significant differences were identified in the female subjects (OR = 1.07, 95%CI: 0.52–2.20, P = 0.85). Central corneal thickness (CCT) is lower in KC patients by 75 µm as compared to normal controls.[4, 5] The incidence of KC is approximately 1 per 2,000, and its prevalence is 54.5 per 100,000. keywords: allele; association; col4a4; gene; keratoconus; patients; pcr; polymorphisms; rs2228557; rs4898; timp-1 cache: jovr-7448.pdf plain text: jovr-7448.txt item: #170 of 284 id: jovr-7449 author: Tzamalis, Argyrios; Kynigopoulos, Myron; Pallas, Grigoris; Tsinopoulos, Ioannis; Ziakas, Nikolaos title: Influence of Intraocular Lens Asphericity and Blue Light Filtering on Visual Outcome, Contrast Sensitivity, and Aberrometry after Uneventful Cataract Extraction date: 2020-07-29 words: 5405 flesch: 45 summary: The yellow tint of BLF IOLs replicates the spectral transmission properties of the aged human crystalline lens in a much closer manner than the UV light-filtering IOLs do.[13] While the possible visual benefits of BLF IOLs are still under debate, controversy has been raised whether a yellow-tinted IOL could modify the visual performance of patients, specifically regarding the postoperative best-corrected visual acuity (BCVA), contrast sensitivity, color vision, and glare. Theoretically, BLF IOLs may induce a reduction in mesopic and scotopic visual performance attributed to the Purkinje shift, where differing peaks of spectral sensitivity for scotopic and photopic vision are identified.[1, 3] Violet and blue lights are much more important for vision in dim-light environments than in bright- light environments, providing 45% of rod-mediated aphakic scotopic sensitivity but only 7% of photopic sensitivity for an iso-illuminance light source.[1, 2] However, the results reported in the literature are controversial regarding postoperative contrast sensitivity after the BLF-IOL implantation and do not indicate a significant decrease in the mesopic and scotopic visual function. keywords: aspheric; blf; blue; cataract; contrast; intraocular; iol; iols; light; sensitivity; vision cache: jovr-7449.pdf plain text: jovr-7449.txt item: #171 of 284 id: jovr-7450 author: Razeghinejad, Reza; Tajbakhsh, Zahra; Beigom Masoumpour, Masoumeh ; Nowroozzadeh, M. Hossein title: Intraocular Pressure Changes after Water Drinking Test in Surgically Treated Primary Congenital Glaucoma date: 2020-07-29 words: 4642 flesch: 54 summary: The following parameters were assessed: IOP trough (lowest IOP after drinking water), IOP peak (highest IOP after drinking water), IOP mean (the mean of the four IOPs after drinking water), IOP fluctuation (difference between peak IOP and baseline), IOP range (difference between peak IOP and lowest IOP reading after drinking water), and end-pressure difference (IOP at 60 min versus baseline). However, the IOP fluctuation in our GDD group (2.5 mmHg) was lower than the value in POAG patients with GDD (3.6 mmHg).[11] Several studies have suggested that IOP fluctuation is an important contributor to the risk of glaucoma progression.[8, 17] The Early Manifest Glaucoma Trial showed that even a 1 mmHg increase in IOP was associated with an 11% increase in the hazard ratio for glaucoma progression.[18] The Advanced Glaucoma Intervention Study Group suggested that IOP peaks should be below 18 mmHg to prevent visual- field deterioration in patients with moderate- or advanced-stage glaucoma.[19] As glaucoma progression is correlated with IOP peaks and fluctuations,[20] accurate identification of at-risk patients has become imperative as the first step JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 3, JULY-SEPTEMBER 2020 321 Water Drinking Test in Congenital Glaucoma; Razeghinejad et al Table 3. keywords: baseline; drinking; gdd; glaucoma; iop; mean; min; patients; test; water; wdt cache: jovr-7450.pdf plain text: jovr-7450.txt item: #172 of 284 id: jovr-7451 author: Esfandiari, Hamed; Prager, Alisa; Hassanpour, Kiana; P. Kurup, Sudhi ; Mets-Halgrimson, Rebecca ; Yoon, Hawke; Lasky Zeid, Janice ; B. Mets, Marilyn ; Rahmani, Bahram title: The Long-term Visual Outcomes of Primary Congenital Glaucoma date: 2020-07-29 words: 3092 flesch: 53 summary: We did not find any association between the age at diagnosis and final visual acuity. Visual acuity outcomes in pediatric glaucomas. keywords: glaucoma; iop; outcomes; patients; pcg; study; vision; visual cache: jovr-7451.pdf plain text: jovr-7451.txt item: #173 of 284 id: jovr-7452 author: Lee, Andy; G Garg, Pooja ; T Lyon, Alice ; Mirza, Rukhsana; K Gill, Manjot title: Long-term Outcomes of Treat and Extend Regimen of Anti-vascular Endothelial Growth Factor in Neovascular Age-related Macular Degeneration date: 2020-07-29 words: 5590 flesch: 56 summary: Since then, several other retrospective studies have proposed using a TAE approach as an alternate to monthly or PRN dosing to reduce treatment burden while maintaining or improving visual outcome.[10–12] Despite the multitude of trials demonstrating the safety and efficacy of anti-VEGF drug therapy, there have been limited studies describing the long-term follow-up of anti-VEGF treatment. Of the treated patients, 61.2% received monotherapy with no difference in visual acuity outcomes or number of injections between the agents used. keywords: acuity; age; anti; eyes; injections; macular; patients; study; treatment; vegf; year cache: jovr-7452.pdf plain text: jovr-7452.txt item: #174 of 284 id: jovr-7454 author: Sabbaghi, Hamideh; Ahmadieh, Hamid; Jalili, Jalil; Behnaz, Nazanin; Fakhri, Maryam; Suri, Fatemeh; Rajabpour, Mojtaba; Entezari, Morteza; Daftarian, Narsis title: Choroidal Thickness in Different Types of Inherited Retinal Dystrophies date: 2020-07-29 words: 6475 flesch: 56 summary: However, no significant reduction in choroidal thickness was reported in RP patients in the study by Chhablani et al.[19] The mean subfoveal choroidal thickness in healthy controls (336.79 ± 82.75 µm) was greater than that in RP patients (P < 0.001), but did not differ significantly from mean subfoveal choroidal thickness in other IRDs including Usher syndrome, cone-rod dystrophy, and Stargardt disease. keywords: disease; dystrophy; eyes; patients; research; stargardt; study; thickness cache: jovr-7454.pdf plain text: jovr-7454.txt item: #175 of 284 id: jovr-7455 author: Hassankarimi, Homa; Jafarzadehpur, Ebrahim; Mohammadi, Alireza; Mohammad Reza Noori, Seyed title: Low-contrast Pattern-reversal Visual Evoked Potential in Different Spatial Frequencies date: 2020-07-29 words: 4987 flesch: 55 summary: Gaussian wavelet transform and classifier to reliably estimate latency of multifocal visual evoked potentials (mfVEP). Studies of human visual physiopathology with visual evoked potentials. keywords: analysis; coefficients; contrast; cpd; detail; frequencies; frequency; level; pattern; potentials; reversal; time; transform; vep; wavelet cache: jovr-7455.pdf plain text: jovr-7455.txt item: #176 of 284 id: jovr-7456 author: A. Azari, Amir ; Arabi, Amir title: Conjunctivitis: A Systematic Review date: 2020-07-29 words: 13416 flesch: 43 summary: hydrogen peroxide.[44] The American Academy of Ophthalmology recommends using a 1:10 dilute bleach solution (sodium hypochlorite) to disinfect the office equipment and instruments against common infectious agents encountered in eye care clinics including the adenoviruses.[45] Due to the highly contagious nature of viral conjunctivitis, frequent hand washing, meticulous disinfection of medical instruments, and isolation of conjunctivitis patients from the rest in the healthcare provider’s office has been recommended.[46] The incubation period for the adenovirus is approximately 5–12 days, while the infected individuals can transmit the disease for up to 14 days from the time they are infected.[41] There is no single effective treatment modality for viral conjunctivitis; however, use of frequent artificial tears, antihistamines containing eye drops, or cold-compresses seem to alleviate many of the clinical symptoms that are associated with this condition.[47, 48] Topical and oral antiviral medications do not appear to be useful.[47, 48] Kam KY, Ong HS, Bunce C, Ogunbowale L, Verma S. Sensitivity and specificity of the AdenoPlus point-of-care system in detecting adenovirus in conjunctivitis patients at an ophthalmic emergency department: a diagnostic accuracy study. keywords: acute; adenoviral; allergy; arabi; azari; bacterial; cases; chronic; clin; condition; conjunctival; conjunctivitis; contact; corneal; diagnosis; discharge; disease; drops; eye; history; involvement; issue; journal; july; keratoconjunctivitis; ocular; ophthalmic; ophthalmology; patients; research; review; september; signs; study; surface; symptoms; topical; treatment; vernal; vision; vkc; volume cache: jovr-7456.pdf plain text: jovr-7456.txt item: #177 of 284 id: jovr-7457 author: A. Casey, Geoffrey ; M. Papp, Kimberly ; M. MacDonald, Ian title: Ocular Gene Therapy with Adeno-associated Virus Vectors: Current Outlook for Patients and Researchers date: 2020-07-29 words: 2062 flesch: 42 summary: Researchers studying ocular gene therapies and clinicians enrolling patients in clinical trials must recognize the current limitations of these therapies to properly manage expectations and avoid disappointment, but we believe that gene therapies are well on their way to successful, widespread utilization to treat heritable ocular disorders. https://orcid.org/0000-0001-7472-8385 Abstract In this “Perspective”, we discuss ocular gene therapy – the patient’s perspective, the various strategies of gene replacement and gene editing, the place of adeno- associated virus vectors, routes of delivery to the eye and the remaining question - “why does immunity continue to limit efficacy?” keywords: aav; cells; gene; patients; therapy; trial; vector cache: jovr-7457.pdf plain text: jovr-7457.txt item: #178 of 284 id: jovr-7458 author: Naveed, Hasan; Leung, Victor; Zarei-Ghanavati, Mehran ; Leak, Christopher; Liu, Christopher title: Ophthalmic Workplace Modifications for the Post-COVID Era date: 2020-07-29 words: 5019 flesch: 41 summary: Such patients can then be booked into designated face-to-face clinics. In a century’s time, we want future ophthalmologists to be able to look back and say their forebears had done well in the year 2020 protecting ophthalmology patients and staff and laid foundations for new pathways and new ways of delivering safe ophthalmic care, thus transforming ophthalmology despite the challenge of high volume and high risk. keywords: clinics; control; covid-19; eye; face; healthcare; masks; microns; ophthalmic; pandemic; patients; respiratory; risk; sars; staff; workplace cache: jovr-7458.pdf plain text: jovr-7458.txt item: #179 of 284 id: jovr-7460 author: X. Zheng, Cindy ; H. Uhr, Joshua ; D. Deaner, Jordan ; M. Lin, Michael ; J. Moster, Stephen ; Razeghinejad, Reza title: Orbital Cellulitis Following Uncomplicated Glaucoma Drainage Device Surgery: Case Report and Review of Literature date: 2020-07-29 words: 4600 flesch: 58 summary: 0 N R N on e N A 9 6 m on th s H an d m ot io ns 12 N on e C yc lo ph ot oc oa gu la tio n at sa m e tim e as G D D ex pl an ta tio n 10 2 m on th s 20 /3 2 28 El ev at ed in tr ao cu la rp re ss ur e C yc lo ph ot oc oa gu la tio n 11 N R C ou nt fin ge rs N R N on e N A N R ,n ot re po rt ed ;N A ,n ot ap pl ic ab le ;G D D ,g la uc om a dr ai na ge de vi ce JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 3, JULY-SEPTEMBER 2020 417 Orbital Cellulitis Following Uncomplicated GDD Surgery; Zheng et al Blood cultures were negative in all tested cases.[1, 3–5, 7] Presumably, the infection remained localized to the orbit. Previous studies have shown that steroids can help reduce the cytokine load and improve outcomes in bacterial OC.[12, 13] 414 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 15, ISSUE 3, JULY-SEPTEMBER 2020 Orbital Cellulitis Following Uncomplicated GDD Surgery; Zheng et al Ta b le 1. D em og ra ph ic s, ba se lin e cl in ic al ch ar ac te ris tic s, an d in iti al pr es en ta tio n of or bi ta lc el lu lit is af te rg la uc om a dr ai na ge de vi ce im pl an ta tio n C a se N o . keywords: gdd; n n; n r cache: jovr-7460.pdf plain text: jovr-7460.txt item: #180 of 284 id: jovr-7461 author: Azimizadeh, Mahdieh; Maryam Hosseini, Seyedeh ; Babaei, Esmaeil title: Focal Choroidal Excavation in a Case of Choroidal Osteoma Associated with Choroidal Neovascularization date: 2020-07-29 words: 1845 flesch: 43 summary: Initially, FCE was defined as choroidal excavation in the submacular area without posterior staphyloma, any positive history of trauma, or any chorioretinal disease; however, some chorioretinal disorders such as CSC, PCV, CNV, and choroidal osteoma have been reported in association with FCE.[7] Mahdieh Azimizadeh: https://orcid.org/0000-0001-9467-4249 Esmaeil Babaei: https://orcid.org/0000-0001-8490-3589 Abstract Purpose: To report a case of choroidal osteoma associated with reactivation of choroidal neovascularization (CNV) and development of focal choroidal excavation (FCE). keywords: cnv; excavation; eye; fce; oct; osteoma cache: jovr-7461.pdf plain text: jovr-7461.txt item: #181 of 284 id: jovr-7463 author: Patel, Shyam; Robin, Alexander title: Cytomegalovirus Retinitis in a Patient on Long-term Mycophenolate Mofetil Treatment for Myasthenia Gravis date: 2020-07-29 words: 1035 flesch: 43 summary: The prevalence of CMV retinitis in HIV patients has decreased since the advent of highly active antiretroviral therapy (HAART).[2] However, the rate of CMV retinitis in non-HIV patients is increasing, likely due to the use of aggressive immunosuppressive agents.[1] CMV retinitis treatment in HIV patients involves HAART and antiviral therapy.[1] keywords: cmv; hiv; patients; retinitis cache: jovr-7463.pdf plain text: jovr-7463.txt item: #182 of 284 id: jovr-7464 author: Salimi, Ali; Ing, Edsel; Nianiaris, Nicholas title: Suicide and Laser Refractive Surgery date: 2020-07-29 words: 1323 flesch: 40 summary: The possible sequelae of LRS include dry eye syndrome, blurred vision, glare, and night vision disturbance that are usually transient, but sometimes persist.[1] Psychiatric complications such as psychosis, depression, suicidal ideation, attempted suicide or completed suicide (PDS) following LRS are rare,[2] but generate marked media attention.[3, 4] Given the tragedy of suicide after LRS, we reviewed the PubMed, Embase, PsycINFO, and Google Scholar databases from inception to October 2019 using keywords and MeSH terms “laser refractive surgery” and “suicide”. Given that, the incidence rate of completed suicide and PDS in the US is estimated to be 7 per 100,000,000 individuals and 4 per 10,000,000 individuals undergoing LRS per annum, respectively. keywords: eye; laser; lasik; lrs; suicide; surgery cache: jovr-7464.pdf plain text: jovr-7464.txt item: #183 of 284 id: jovr-7465 author: Rahmani, Saeed; Nazari, Mohammadreza; Akbarzadeh Baghban, Alireza ; Ghassemi-Broumand, Mohammad title: How Much of Hazardous Blue Light is Transmitted By Spectacle Lenses? date: 2020-07-29 words: 919 flesch: 55 summary: Saeed Rahmani: https://orcid.org/0000-0001-6330-4405 J Ophthalmic Vis Res 2020; 15 (3): 435–437 Dear Editor, The first region of the visible light spectrum is called blue light. Blue light is beneficial to humans in color vision, night vision, and circadian rhythms.[1, 2] However, this type of light raises concerns as it carries high energy and can cause ocular damages, such as photic retinopathy. keywords: lenses; light; spectacle cache: jovr-7465.pdf plain text: jovr-7465.txt item: #184 of 284 id: jovr-7466 author: Rajavi, Zhale; Safi, Sare; Mohammadzadeh, Maryam title: Guidance for Ophthalmologists and Ophthalmology Centers during the COVID-19 Pandemic date: 2020-07-29 words: 1982 flesch: 34 summary: The patients should be examined alone (without companions) and if needed only one person can accompany elderly patients and children.[6] • Avoid crowding in the waiting room while maintaining at least 3 m distance between patients. Ophthalmologists are at high risk for being infected or transmitting the virus due to the following reasons: examining patients with conjunctivitis or asymptomatic carriers from a short distance (usually < 20 cm), the long duration of eye examinations/procedures (> 15 min), touching patients’ eyelids during slit- lamp examination, and the possibility of viral shedding and transmission in contact with ocular secretions. keywords: covid-19; march; ophthalmologists; patients; research; vision cache: jovr-7466.pdf plain text: jovr-7466.txt item: #185 of 284 id: jovr-7777 author: Luong Hien, Doan title: How Do We Manage HLA-B27-associated Ocular Inflammation Refractory or Intolerant to Conventional Immunomodulatory Therapy? date: 2020-10-25 words: 2403 flesch: 47 summary: 7. Rathinam SR, Gonzales JA, Thundikandy R, Kanakath A, Murugan SB, Vedhanayaki R, et al. Effect of corticosteroid-sparing treatment with mycophenolate mofetil vs methotrexate on inflammation in patients with uveitis: a randomized clinical trial. Biester S, Deuter C, Michels H, Haefner R, Kuemmerle-Deschner J, Doycheva D, et al. Adalimumab in the therapy of uveitis in childhood. keywords: inflammation; infliximab; patients; study; therapy; treatment; uveitis cache: jovr-7777.pdf plain text: jovr-7777.txt item: #186 of 284 id: jovr-7778 author: Demirci, Hakan; Wang, Yichun; Li, Qiaochu; Lin, Cheng-mao; Kotov, Nicholas A; Diniz Grisolia, Anna Beatriz ; Guo, Jay L title: Penetration of Carbon Nanotubes into the Retinoblastoma Tumor after Intravitreal Injection in LHBETATAG Transgenic Mice Reti-noblastoma Model date: 2020-10-25 words: 4174 flesch: 54 summary: Eye tumors in the LHBETATAG transgenic mouse model showed the histological features of human retinoblastoma with endophytic and exophytic growth with invasion of the retina, choroid, and optic nerve.[20] This animal model has been extensively characterized and develops bilateral multifocal retinal tumors that are stable and grow at the predictable rate.[20] Examination of each mice was performed and it was confirmed that retinoblastoma tumor fills about 50% of the globe. keywords: bio; carbon; cnt; cnts; control; eyes; fitc; intensity; mice; penetration; retinoblastoma; tumor cache: jovr-7778.pdf plain text: jovr-7778.txt item: #187 of 284 id: jovr-7779 author: Moniritilaki, Mohammadreza; Badakhsh, Maryam; Ehsaei, Asieh; Daneshvar, Ramin title: The Effect of Contact Lens–spectacle Reversed Galilean Telescope on the Visual Field of Patients with Open-angle Glaucoma date: 2020-10-25 words: 3474 flesch: 54 summary: Although patients with the restricted visual field have high demands and motivations to use visual field expanding instruments, few devices are available.[7] Visual field index (VFI) improved from a basic value of 44.38 ± 26.96 to 49.30 ± 29.83 percent by using the reversed telescope (P < 0.001). keywords: field; galilean; galilean telescope; glaucoma; lens; patients; telescope; visual cache: jovr-7779.pdf plain text: jovr-7779.txt item: #188 of 284 id: jovr-7780 author: Liu, Lei; Yu, Ying; Peng, Qiuyue; Porsborg, Simone R; Nielsen, Frederik M; Jørgensen, Annemette; Grove, Anni; Bath, Chris; Hjortdal, Jesper; Christiansen, Ole B; Fink, Trine; Zachar, Vladimir title: Distribution of Stromal Cell Subsets in Cultures from Distinct Ocular Surface Compartments date: 2020-10-25 words: 4463 flesch: 51 summary: CSCs, corneal stromal cells; LSCs, limbal stromal cells; SSCs, scleral stromal cells; ASCs, adipose-derived stem cells; EMSCs, endometrial mesenchymal stem cells; HFFs, human foreskin fibroblasts. 4A). CSCs, corneal stromal cells; LSCs, limbal stromal cells; SSCs, scleral stromal cells. keywords: cd146; cd34; cells; compartments; corneal; expression; limbal; mesenchymal; stem; stem cells; stromal; stromal cells; surface cache: jovr-7780.pdf plain text: jovr-7780.txt item: #189 of 284 id: jovr-7781 author: Neekhra, Aneesh; Tran, Julia; Pham, Khoa; Sharma, Ashish; Chwa, Marilyn; Luthra, Saurabh; a, Ana L. Grmajo; Mansoor, Saffar; Kuppermann, Baruch D.; Kenney, Cristina title: Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro date: 2020-10-25 words: 6711 flesch: 53 summary: In contrast, R28 cells exposed to 7kCh continued to have elevated caspase- 3/7, -8, and -12 activities (between 25.7% decrease and 17.5% increase in msi, P > 0.05) regardless of the pretreatment. Our results show that these drugs are effective in ARPE-19 cells but not in R28 cells, implicating the need for a multidrug approach or novel therapies to inhibit 7kCh in various cell types. keywords: 7kch; activity; apoptosis; arpe-19; caspase-3/7; cells; et al; figure; fmk; memantine; msi; r28; r28 cells; simvastatin cache: jovr-7781.pdf plain text: jovr-7781.txt item: #190 of 284 id: jovr-7785 author: Maleki, Arash; Stephenson, Andrew Phillips; Hajizadeh, Fedra title: Topical Interferon Alpha 2b in the Treatment of Refractory Diabetic Macular Edema date: 2020-10-25 words: 2924 flesch: 49 summary: Methods: In this retrospective interventional case series, five eyes of three individuals with diabetic macular edema resistant to multiple intravitreal injections of anti-vascular endothelial growth factor drugs and macular photocoagulation were included. Two eyes had undergone pars plana vitrectomy, one for diabetic macular edema and the other for rhegmatogenous retinal detachment. keywords: alpha; diabetic; dme; interferon; macular; month; topical; treatment cache: jovr-7785.pdf plain text: jovr-7785.txt item: #191 of 284 id: jovr-7786 author: Bajwa, Asima; Maleki, Arash; Payal, Abhishek R; Fandiño, Adriana; Padrón, María Inés Menéndez; Walsh, Marisa; Foster, Charles Stephen title: Efficacy and Safety of Infliximab in HLA-B27-associated Ocular Inflammation Refractory or Intolerant to Conventional Immunomodulatory Therapy date: 2020-10-25 words: 5774 flesch: 47 summary: (%) 17 (70.8) AS 9 (37.5) AS and RA 2 (8.3) AS and IBD 1 (4.1) PA 2 (8.3) NSA 2 (8.3) JIA 1 (4.2) Conventional therapy Before infliximab patients (n = 24) (%) After infliximab patients (n = 24) (%) https://orcid.org/0000-0002-5823-3312 Arash Maleki: https://orcid.org/0000-0001-5533-9798 Charles Stephen Foster: https://orcid.org/0000-0003-4760-8390 Abstract Purpose: To determine the efficacy and safety of infliximab therapy in patients with HLA B-27-associated ocular inflammation resistant or intolerant to conventional immunomodulatory therapy. keywords: b27; dose; eyes; hla; inflammation; infliximab; infliximab therapy; months; patients; remission; study; therapy; treatment; uveitis cache: jovr-7786.pdf plain text: jovr-7786.txt item: #192 of 284 id: jovr-7787 author: Furino, Claudio; Niro, Alfredo; Reibaldi, Michele; Grassi, Maria Oliva; Boscia, Francesco; Alessio, Giovanni title: Efficacy of Intravitreal Dexamethasone Implant in Different Patterns of Diabetic Macular Edema date: 2020-10-25 words: 4828 flesch: 52 summary: Original Article Efficacy of Intravitreal Dexamethasone Implant in Different Patterns of Diabetic Macular Edema Claudio Furino, MD, PHD1; Alfredo Niro, MD, PHD2; Michele Reibaldi, MD, PHD3 Francesco Boscia, MD4; Giovanni Alessio, MD1 1Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari, Bari, Italy 2Eye Clinic, Hospital “S. G. MOSCATI”, ASL TA, Taranto, Italy 3Eye Clinic, University of Catania, Catania, Italy 4Department of Surgical, Microsurgical and Medical Sciences, Eye Clinic, University of Sassari, Sassari, Italy ORCID: Claudio Furino: https://orcid.org/0000-0003-0254-7432 Abstract Purpose: Different patterns of diabetic macular edema (DME) suggest different pathogenesis and drug response. Optical coherence tomographic patterns of diabetic macular edema. keywords: crt; crv; diabetic; edema; group; implant; macular; mean; months cache: jovr-7787.pdf plain text: jovr-7787.txt item: #193 of 284 id: jovr-7788 author: Mohamadpour, Mehrdad; Khorrami-Nejad, Masoud ; Kiarudi, Mohammad Yaser; Khosravi, Keivan title: Evaluating the Ectasia Risk Score System in Cancelled Laser In Situ Keratomileusis Candidates date: 2020-10-25 words: 2878 flesch: 50 summary: Analysis of ectasia after laser in situ keratomileusis: risk factors. Risk scores of 5 or more, 4 or more, and 3 or more were found in 35 (2.1%), 92 (5.4%), and 208 (12.2%) eyes with a normal topography, respectively. keywords: ectasia; eyes; lasik; risk; score; system; thickness cache: jovr-7788.pdf plain text: jovr-7788.txt item: #194 of 284 id: jovr-7789 author: Esfandiari, Hamed; Hassanpour, Kiana; Knowlton, Peter; Shazly, Tarek; Yaseri, Mehdi; Loewen, Nils A. title: Combining Baerveldt Implant with Trabectome Negates Tube Fenestration: A Coarsened-matched Comparison date: 2020-10-25 words: 5178 flesch: 56 summary: Thirty patients (59%) underwent phacoemulsification at the time of glaucoma surgery in each group (P =1.00). (B) survival plots of the BT and B for subgroup analysis separated by (B) glaucoma surgery alone and (C) same-session phacoemulsification (lower right). keywords: baerveldt; bt group; glaucoma; group; implant; iop; phacoemulsification; surgery; trabectome; tube cache: jovr-7789.pdf plain text: jovr-7789.txt item: #195 of 284 id: jovr-7790 author: Mohammadpour, Mehrdad; Masoumi, Ahmad; Dehghan, Mahmoud; Hashemian, Mohammad Nasser; Karami, Shahab Addin; Mahmoudi, Alireza title: MyoRing Implantation with and without Corneal Collagen Crosslinking for the Management of Keratoconus date: 2020-10-25 words: 4222 flesch: 50 summary: Results: Data of 47 patients were available at the end of the study; 28 in the MyoRing group and 19 in the MyoRing + CXL group. logMAR (P < 0.05) in the MyoRing + CXL group and from 0.65 ± 0.38 keywords: collagen; corneal; cxl; group; implantation; keratoconus; logmar; myoring cache: jovr-7790.pdf plain text: jovr-7790.txt item: #196 of 284 id: jovr-7791 author: Anvari, Pasha; Najafi, Amin; Mirshahi, Reza; Sardarinia, Mahsa; Ashrafkhorasani, Maryam; Kazemi, Pegah; Aghai, Gholamhoseyn; Habibi, Abbas; Falavarjani, Khalil Ghasemi title: Comparison of Superficial and Deep Foveal Avascular Zone Area in Healthy Subjects Using Two Spectral Domain Optical Coherence Tomography Angiography Devices date: 2020-10-25 words: 3630 flesch: 47 summary: The Bland-Altman plots showing lack of agreement between Spectralis and Optovue devices in measuring FAZ area at A) superficial, B) deep and C) full retinal slabs. In conclusion, OCTA measurements are reliable for evaluation of FAZ area in various retinal slabs, however, commercially available devices may yield different values depending on their segmentation algorithms. keywords: angiography; area; coherence; devices; faz; octa; optovue; spectralis; tomography; zone cache: jovr-7791.pdf plain text: jovr-7791.txt item: #197 of 284 id: jovr-7792 author: Gillmann, Kevin; Mansouri, Kaweh title: Minimally Invasive Surgery, Implantable Sensors, and Personalized Therapies date: 2020-10-25 words: 7789 flesch: 48 summary: This is particularly problematic in glaucoma patients when inflammation is exacerbated through four mechanisms: (1) the predisposition of patients to conjunctival fibrosis through long-term use of topical prostaglandins or toxic preservative, both of which were associated with local inflammation,[28, 29] (2) the surgical procedure itself, (3) subconjunctival flow, by itself, constitutes a persistent mechanical stress to local tissue, which was shown to translate into pro-inflammatory biochemical signals,[39–41] and (4) the mere presence of aqueous humor in the subconjunctival space, where it is not naturally present, was shown to promote tissue fibrosis. Aqueous angiographic outflow improvement after trabecular microbypass in glaucoma patients. keywords: aqueous; canal; gillmann; glaucoma; innovations; intraocular; iop; issue; journal; migs; ophthalmol; outflow; patients; pressure; research; schlemm; subconjunctival; surgery; topical; treatment; vision; volume cache: jovr-7792.pdf plain text: jovr-7792.txt item: #198 of 284 id: jovr-7793 author: Mazloumi, Mehdi; Dalvin, Lauren A; Abtahi, Seyed-Hossein; Yavari, Negin; Yaghy, Antonio; Mashayekhi, Arman; Shields, Jerry A; Shields, Carol L title: Photodynamic Therapy in Ocular Oncology date: 2020-10-25 words: 7129 flesch: 47 summary: Retinal vasoproliferative tumors: comparative clinical features of primary vs secondary tumors in 334 cases. Retinal vasoproliferative tumor - a proposal for classification. keywords: cases; choroidal; et al; hemangioma; melanoma; ophthalmol; patients; pdt; photodynamic; regression; retina; shields; shields cl; therapy; treatment; tumor cache: jovr-7793.pdf plain text: jovr-7793.txt item: #199 of 284 id: jovr-7794 author: Cruzado-Sánchez, Deivy ; Saavedra-Mejía, Luis A. ; Tellez, Walter A.; Maquera-Torres, Grissnery ; Serpa-Frias, Solon title: Metastatic Intraocular Tumor Due to Colorectal Adenocarcinoma: Case Report and Literature Review date: 2020-10-25 words: 3091 flesch: 53 summary: Characteristics of previous intraocular metastasis cases due to colorectal adenocarcinoma reported in the literature Author Year of publication Sex Age Colorectal cancer Intraocular metastasis Other sites of metastasis Survival time (months) Primary lesion TNM or stage Intraocular site Time to diagnosis (months) Symptom Treatment Kennedy[24] 1958 M 51 Rectosigmoid NS Retina S Blurred vision Enucleation None 9 Howard[27]∗ 1968 M 63 Colon NS Retina, choroid 36 Visual disturbance Enucleation Orbit 16 Cole[7]∗ 1985 F 48 Rectum T4a Choroid 23 BY KNOWLEDGE E 565 http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v15i4.7794&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR Ocular Metastasis from Colorectal Adenocarcinoma; Cruzado-Sánchez et al The aim of this report is to describe the clinical and histopathological findings of a case of intraocular metastasis from colorectal adenocarcinoma and to carry out a literature review. keywords: adenocarcinoma; cancer; case; choroid; choroidal; colon; colorectal; intraocular; metastasis; tumor; vision cache: jovr-7794.pdf plain text: jovr-7794.txt item: #200 of 284 id: jovr-7795 author: Zarei-Ghanavati, Mehran ; Davoodabadi, Mahmood; Shahbazi, Ahad title: Amniotic Membrane Patch Graft in Management of Double Chamber after Deep Anterior Lamellar Keratoplasty date: 2020-10-25 words: 1639 flesch: 55 summary: We decided to patch DM perforation site with AM graft. The incidence of DM perforation during DALK was reported up to 39%.[2] DM perforation may cause double anterior chamber between donor stroma and recipient DM. keywords: chamber; graft; membrane; patch; perforation cache: jovr-7795.pdf plain text: jovr-7795.txt item: #201 of 284 id: jovr-7797 author: Mohammad-Rabei, Hossein ; Azari, Amir A.; Arabi, Amir title: Traumatic Endothelial Corneal Rings date: 2020-10-25 words: 686 flesch: 48 summary: Sung Jin Kim et al reported that the mean duration for the presence of rings was 4.6 days on average.[2] When the total number of endothelial cells lost is small, as evident when only a few corneal endothelial rings are present, one should expect an unremarkable clinical course; however, with more severe and extensive injuries, ophthalmologists should be wary of potential corneal decompensation if further endothelial cell loss is anticipated form future intraocular surgeries and procedures.[4] In our case, traumatic corneal endothelial rings were clinically visible immediately after the injury, and resolved completely within one week without any specific treatment. Ultrastructure of traumatic corneal endothelial rings. keywords: corneal; endothelial; rings cache: jovr-7797.pdf plain text: jovr-7797.txt item: #202 of 284 id: jovr-7798 author: Goel, Neha; Mehta, Aanchal; Batra, Jyoti; Choudhry, Reena title: Anterior Chamber Migration of Intravitreal Dexamethasone Implant in an Eye with Scleral-fixated Intraocular Lens date: 2020-10-25 words: 1163 flesch: 45 summary: Due to the recent anterior migration of DEX implant, three monthly doses of intravitreal ranibizumab were administered. Suboptimal visual and anatomical results led us to inject DEX implant again, with care taken not to dilate the pupil fully at any time. keywords: anterior; chamber; dex; implant; migration cache: jovr-7798.pdf plain text: jovr-7798.txt item: #203 of 284 id: jovr-7801 author: Srirampur, Arjun; Balijepalli, Pasyanthi title: Black Diaphragm Intraocular Lens in Patients with Aniridia date: 2020-10-25 words: 547 flesch: 52 summary: Black diaphragm intraocular lens implantation in patients with aniridia. 3. Dong X, Xu H, Yu B, Ying L, Xie L. Long-term outcome of black diaphragm intraocular lens implantation in traumatic aniridia. keywords: aniridia; diaphragm cache: jovr-7801.pdf plain text: jovr-7801.txt item: #204 of 284 id: jovr-7802 author: Karimi, Saeed; Arabi, Amir; Shahraki, Toktam; Safi, Sare title: Central Serous Chorioretinopathy in a Case of Regressed Familial Retinoblastoma date: 2020-10-25 words: 2177 flesch: 43 summary: As there was no sign of retinoblastoma recurrence or secondary malignancy and the clinical findings did not reflect late-onset retinopathy related to prior treatment, a close follow-up was planned. Although some conditions with choroidal origin such as radiation choroidopathy and choroidal neovascularization have been reported after treatment of retinoblastoma,[23] in case of subretinal exudation in an eye with regressed retinoblastoma, retinoblastoma recurrence or secondary malignant tumors are considered prior to choroidal conditions. keywords: case; chorioretinopathy; eye; ophthalmol; recurrence; retinoblastoma; serous; vision cache: jovr-7802.pdf plain text: jovr-7802.txt item: #205 of 284 id: jovr-8242 author: Soheili, Zahra-Soheila title: Editorial — Systems Biology Approach for Identification of Essential Growth Factors in Retinal Regeneration date: 2021-01-20 words: 985 flesch: 37 summary: Growth factors play a fundamental role in a variety of cellular processes such as proliferation, migration, differentiation, and multicellular morphogenesis.[1] Growth factors expedite tissue growth/regeneration by providing the right signals to the cells.[2] Systems biology- related approaches help us understand the mechanisms underlying retinal tissue engineering and investigate the effect of growth factors through protein–protein interaction network analyses. Network centrality analysis using different criteria has the potential to reveal growth factors important for retinal regeneration. keywords: centrality; factors; growth; network; proteins cache: jovr-8242.pdf plain text: jovr-8242.txt item: #206 of 284 id: jovr-8243 author: Nishat H, Ahmed ; Satpathy, Gita; Chawla, Rohan; Tandon, Radhika title: Multiplex PCR for Detection of Herpes Simplex Viruses Type-1 and Type-2, Cytomegalovirus, Varicella-zoster Virus, and Adenovirus in Ocular Viral Infections date: 2021-01-20 words: 4110 flesch: 44 summary: (a) Multiplex PCR simultaneously detecting all five viruses, (b) Ocular specimens positive for HSV-2 and VZV by multiplex PCR, and (c) Ocular specimens positive for CMV, VZV, HSV-1, and Adenovirus by multiplex PCR. of ocular specimens, showing viral detection in 24.2% of tear samples received. The conventional methods used for diagnosing ocular viral infections are either less sensitive and/or specific, require sophisticated equipment and infrastructure and/or explicit expertise, or have a long turnaround time. keywords: adenovirus; cmv; infections; multiplex; pcr; pcrs; reaction; samples; uniplex; viruses; vzv cache: jovr-8243.pdf plain text: jovr-8243.txt item: #207 of 284 id: jovr-8244 author: Karjou, Zahra; Jafarinasab, Mohammad-Reza; Seifi, Mohammad-Hassan; Hassanpour, Kiana; Kheiri, Bahareh title: Secondary Piggyback Intraocular Lens for Management of Residual Ametropia after Cataract Surgery date: 2021-01-20 words: 4460 flesch: 46 summary: Furthermore, this procedure achieves the best results when performed soon before the formation of capsular adhesions, which is not feasible in all patients.[4, 7, 10] Recently, secondary piggyback IOL implantation has received more attention due to its promising safety profile and easier surgical techniques.[6, 15–18] Additionally, there are many studies reporting predictable refractive outcomes with the application of power calculation of the second IOL, which is not very complicated.[19] Another advantage of a secondary piggyback IOL over IOL exchange is that the implantation of a secondary IOL is a reversible procedure, and if complications such as ILO, pupillary optic capture, pigment dispersion syndrome, or pigmentary glaucoma occur, the removal of piggyback IOL can be considered.[13] The present findings are in line with other studies reporting piggyback IOL implantation. Methods: In this prospective interventional case series, patients who had residual refractive error after cataract surgery and were candidates for secondary piggyback IOL implantation between June 2015 and September 2018 were included. keywords: ametropia; cataract; error; implantation; intraocular; iol; journal; lens; patients; piggyback; surgery cache: jovr-8244.pdf plain text: jovr-8244.txt item: #208 of 284 id: jovr-8245 author: Lin, Jonathan B.; Sheybani, Arsham; Santeford, Andrea; Apte, Rajendra S. title: Longitudinal Growth Differentiation Factor 15 (GDF15) and Long-term Intraocular Pressure Fluctuation in Glaucoma: A Pilot Study date: 2021-01-20 words: 3592 flesch: 51 summary: Methods: Here, we performed a prospective, longitudinal pilot study in nine patients to determine whether changes in AH GDF15 levels from surgery to post-surgery follow-up were associated with IOP fluctuation. GDF15 levels over the follow-up interval, while three had decreased AH GDF15 levels at follow-up approximately six months later [Figure 1]. keywords: fluctuation; gdf15; glaucoma; iop; patients; study; surgery cache: jovr-8245.pdf plain text: jovr-8245.txt item: #209 of 284 id: jovr-8248 author: Mirshahi, Ahmad; Lashay, Alireza; Riazi-Esfahani, Hamid ; Ebrahimiadib, Nazanin; Khojasteh, Hassan; Ghassemi, Fariba; Bazvand, Fatemeh; Khodabande, Alireza; Roohipour, Ramak; Khalili Pour, Elias ; Faghihi, Hooshang title: Intraocular Injection of Stivant® (A Biosimilar to Bevacizumab): A Case Series date: 2021-01-20 words: 3221 flesch: 45 summary: After the application of povidone iodine 5% into the conjunctival sac for about 3 min, intravitreal injection of 1.25 mg/ 0.05 ml Stivant® was performed with a 29-gauge needle (1 ml tuberculin syringes; DispoVan) through the pars JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 1, JANUARY-MARCH 2021 29 A Case Series of Stivant® Intraocular Injection; Mirshahi et al plana 4 mm and 3.5 mm posterior to the limbus in phakic and pseudophakic eyes, respectively. Intravitreal injection of Stivant® from separate glass vials was performed in both eyes of 34 patients with bilateral DME. keywords: eyes; group; injection; patients; reference; stivant cache: jovr-8248.pdf plain text: jovr-8248.txt item: #210 of 284 id: jovr-8249 author: Karimi, Saeed; Movafaghi, Vahid; Arabi, Amir; Shahraki, Toktam; Safi, Sare title: Effects of Oral Vitamin D Supplement Therapy on Clinical Outcomes of Intravitreal Bevacizumab in Diabetic Macular Edema date: 2021-01-20 words: 4041 flesch: 51 summary: Four patients were excluded due to urgent need for supplement therapy (vitamin D level < 10 ng/ml). The mean HbA1c (a) and vitamin D levels (b) in different study groups. keywords: 25(oh)d; control; group; ivb; levels; patients; study; treatment; vitamin; vitamin d cache: jovr-8249.pdf plain text: jovr-8249.txt item: #211 of 284 id: jovr-8250 author: Joondeph, Brian C.; Willems, Paul; Raber, Thomas; Duchateau, Luc; Markoff, Joseph title: Prognostic Factors Associated with Ocriplasmin Efficacy for the Treatment of Symptomatic Vitreomacular Adhesion and Full-thickness Macular Hole: Analysis from Four Studies date: 2021-01-20 words: 8181 flesch: 54 summary: Although our finding that VMA resolution showed a positive correlation with FTMH closure is notable, beyond initial hole size, baseline characteristics predictive of macular hole closure prior to treatment have remained elusive. Duration of vitrectomy and postoperative cataract in the vitrectomy for macular hole study. keywords: baseline; characteristics; closure; ftmh; hole; macular; ocriplasmin; patients; resolution; status; study; treatment; vitreomacular; vma; vma resolution cache: jovr-8250.pdf plain text: jovr-8250.txt item: #212 of 284 id: jovr-8251 author: Beheshtizadeh, Nima; Baradaran-Rafii, Alireza ; Sharifi Sistani, Maryam ; Azami, Mahmoud title: An In-Silico Study on the Most Effective Growth Factors in Retinal Regeneration Utilizing Tissue Engineering Concepts date: 2021-01-20 words: 5991 flesch: 46 summary: Retinal cell regeneration using tissue engineered polymeric scaffolds. Osakada F, Ikeda H, Sasai Y, Takahashi M. Stepwise differentiation of pluripotent stem cells into retinal cells. keywords: analysis; cell; development; engineering; eye; factors; growth; network; process; proteins; regeneration; retina; shh; stat3; stem; study; tissue; tissue engineering cache: jovr-8251.pdf plain text: jovr-8251.txt item: #213 of 284 id: jovr-8253 author: Ali-Akbar Navahi, Roshanak ; Chaibakhsh, Samira; Amirpooya Alemzadeh, Sayyed ; Abri Aghdam, Kaveh title: The Adequate Number of Histopathology Cross-sections of Temporal Artery Biopsy in Establishing the Diagnosis of Giant Cell Arteritis date: 2021-01-20 words: 4098 flesch: 51 summary: Original Article The Adequate Number of Histopathology Cross-sections of Temporal Artery Biopsy in Establishing the Diagnosis of Giant Cell Arteritis Roshanak Ali-Akbar Navahi, MD; Samira Chaibakhsh, PhD; Sayyed Amirpooya Alemzadeh, MD Kaveh Abri Aghdam, MD, PhD Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran ORCID: Roshanak Ali-Akbar Navahi: https://orcid.org/0000-0002-8497-5053 Kaveh Abri Aghdam: https://orcid.org/0000-0001-7568-6455 Abstract Purpose: To determine the appropriate number of histopathological cross-sections that are required for a conclusive diagnosis of giant cell arteritis (GCA). Giant cell arteritis (GCA) is characterized by granulomatous vasculitis of large and medium- sized vessels, and its worldwide annual This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. keywords: arteritis; artery; biopsy; cell; cross; gca; giant; number; sections; specimen; tabs cache: jovr-8253.pdf plain text: jovr-8253.txt item: #214 of 284 id: jovr-8255 author: Bagheri, Masood; Ahoor, Mohammad-Hosein; Jafari, Ahad; Sadat Hashemi, Hesam ; Mohammadkhani, Mehdi title: Pattern of Uveitis in Iran: A Systematic Review date: 2021-01-20 words: 6532 flesch: 52 summary: VKH (5.2) Soheilian M, et al (2004)[30] Idiopathic (52.1) > [25] 0.370 0.311 0.434 Alizadeh L, et al (2017) keywords: behcet; center; disease; et al; iran; ophthalmology; patients; pattern; referral; studies; study; syndrome; uveitis cache: jovr-8255.pdf plain text: jovr-8255.txt item: #215 of 284 id: jovr-8256 author: Nasiri, Naser; Sharifi, Hamid; Bazrafshan, Azam; Noori, Atefeh; Karamouzian, Mohammad; Sharifi, Ali title: Ocular Manifestations of COVID-19: A Systematic Review and Meta-Analysis date: 2021-01-20 words: 5519 flesch: 53 summary: Moreover, Ulhaq et al in a systematic review study up to April 4, 2020 reported that ocular manifestations in COVID-19 patients were 5.5%.[52] They observed the eyelids were irritated by numerous sticky secretions accumulating around the eyelashes, and described mucous filaments, tarsal pseudomembranous, and superficial punctuate keratitis.[39] Assessing and observing the symptoms and ocular manifestations of COVID-19 patients could improve clinicians’ diagnosis of the disease. keywords: conjunctivitis; coronavirus; covid-19; covid-19 patients; disease; et al; eye; manifestations; ophthalmol; patients; review; sars; studies; study; symptoms cache: jovr-8256.pdf plain text: jovr-8256.txt item: #216 of 284 id: jovr-8257 author: Persaud-Sharma, Vishwani ; Hooshmand, Mary A. title: Need for Nurse Practitioner Fellowships in Ophthalmology in the USA date: 2021-01-20 words: 5454 flesch: 31 summary: The primary objective of specialized postgraduate ophthalmic NP fellowships would be to educate and train NPs to be fast, logical thinkers under pressure and during emergent situations; decisions should compile assessment and utilization of prior studied information for accurate situation evaluation, all while rationalizing best patient outcomes, just as US physicians undergo in post-medical school residencies.[35] As Martsolf et al[28] describes, the need to establish NP ophthalmology fellowships coincides with the Institute of Medicine’s seminal report that urges the state boards of nursing, accrediting bodies, the federal government, and healthcare organizations to enact methods that support nurses’ completion of a transition-to-practice program, such as a residency or fellowship, after completing prelicensure, advanced practice degrees, or when transitioning into new clinical practice areas. Physician- nurse practitioner teamwork in primary care practices in New York: a cross-sectional survey. keywords: care; fellowships; medical; need; nps; nurse; ophthalmic; ophthalmology; patient; physician; practice; practitioner; shortage; training cache: jovr-8257.pdf plain text: jovr-8257.txt item: #217 of 284 id: jovr-8259 author: Menezes Palácios, Renato ; Vieira Kayat, Kim ; Eid Farah, Michel ; Devin, François title: Heads-up Digitally Assisted Surgical Viewing with Intraoperative Optical Coherence Tomography for Myopic Schisis Repair date: 2021-01-20 words: 1460 flesch: 42 summary: [Figure 1], without gas tamponade, using intraoperative optical coherence tomography (I-OCT) and digitally-assisted vitreoretinal three- dimensional (3-D) viewing. Surgery was performed using the NGENUITY® system for surgical viewing, and foveal-sparing internal limiting membrane (fs-ILM) peeling was performed without gas tamponade, after confirming the absence of iatrogenic macular hole with I-OCT. keywords: ilm; oct; peeling; viewing cache: jovr-8259.pdf plain text: jovr-8259.txt item: #218 of 284 id: jovr-8260 author: BenAbderrahim, Kais title: Optical Coherence Tomography Findings in Nodular Anterior Scleritis due to Post-Streptococcal Syndrome date: 2021-01-20 words: 1900 flesch: 42 summary: Conclusions: Poststreptococcal syndrome should be considered in the etiology of non- necrotizing anterior scleritis. Anterior scleritis is divided into nodular, diffuse, and necrotizing scleritis. keywords: coherence; poststreptococcal; pss; scleritis; syndrome; tomography cache: jovr-8260.pdf plain text: jovr-8260.txt item: #219 of 284 id: jovr-8261 author: Tsatsos, Michael; Athanasiadis, Ioannis; Gizzi, Corrado; Moschos, Marilita; Sharma, Anant title: Crystalline Lens Staining with Intracameral Phenylephrine During Cataract Surgery date: 2021-01-20 words: 752 flesch: 40 summary: Although Lockington et al reported the possibility of toxicity associated with the presence of free radicals in intracameral phenylephrine formulations, we report no relevant deviations from routine practice in our patients.[3] Lens staining was consistent in all cases where the intracameral phenylephrine formulation was used. The formulation of intracameral phenylephrine (Minims® Phenylephrine Hydrochloride, Bausch & Lomb UK Ltd.) that is routinely used in our practice consists of 0.5 ml of 10% phenylephrine preservative free minims mixed with 0.5 ml of 2% lidocaine and 1 ml of Balanced Salt Solution with adrenaline. keywords: lens; phenylephrine; staining cache: jovr-8261.pdf plain text: jovr-8261.txt item: #220 of 284 id: jovr-8262 author: Mirshahi, Ahmad; Hassanpoor, Narges; Khojasteh, Hassan; Reza Baradaran, Mohammad ; Faghihi, Hooshang; Lashay, Alireza title: Oguchi Disease Associated with Keratoconus date: 2021-01-20 words: 1096 flesch: 53 summary: Prolonged dark adaptation can recover rhodopsin and re-normalize fundus color (Mizuo-Nakamura phenomenon).[2–4] Oguchi disease has been reported in association with retinitis pigmentosa[4] and diabetic retinopathy,[1] but there is no report of its association with keratoconus or any other corneal abnormality up till now. Another case of Oguchi disease was reported by Francois et al with absent scotopic waves in 1956.[1] In conclusion, Oguchi disease can be seen with keratoconus. keywords: dark; disease; eyes; keratoconus; oguchi cache: jovr-8262.pdf plain text: jovr-8262.txt item: #221 of 284 id: jovr-8263 author: Can Ipek, Sefik ; Uslu, Sadettin; Can, Gercek; Ozbagcivan, Ozlem; Cakar Ozdal, Pinar ; Osman Saatci, Ali title: An Unusual Presentation of Vogt–Koyanagi–Harada date: 2021-01-20 words: 1563 flesch: 47 summary: In a recent study, alopecia was present in 38 of the 261 VKH patients (13.9%) in the early disease stages, whereas in 187 of the 373 VKH patients (49.6%) it occurred in the late stages.[4] The presence of serous retinal detachment can be considered as a hallmark of VKH disease. Remarkably, serous retinal detachment was not detected in any visits during the disease course in our case and we believe that this is very unusual in VKH disease. keywords: alopecia; disease; eye; right; vkh cache: jovr-8263.pdf plain text: jovr-8263.txt item: #222 of 284 id: jovr-8264 author: Srirampur, Arjun title: Topical Umbilical Cord Serum for Corneal Epithelial Defects after Diabetic Vitrectomy date: 2021-01-20 words: 820 flesch: 44 summary: 5. Vajpayee RB, Mukerji N, Tandon R, Sharma N, Pandey RM, Biswas NR, et al. Evaluation of umbilical cord serum therapy for persistent corneal epithelial defects. Thirdly, even though the authors have admitted for the absence of dry eye testing in these eyes, they should have performed simple corneal sensations. keywords: corneal; defects; epithelial cache: jovr-8264.pdf plain text: jovr-8264.txt item: #223 of 284 id: jovr-8265 author: Moradian, Siamak; Ebrahim, Marzieh; Kanaani, Azade; Faramarz, Amir; Safi, Sare title: Author's Reply to Topical Umbilical Cord Serum for Corneal Epithelial Defects after Diabetic Vitrectomy date: 2021-01-20 words: 323 flesch: 34 summary: Letter Authors’ Reply Siamak Moradian1,2, MD; Marzieh Ebrahimi3, PhD; Azade Kanaani1, MD; Amir Faramarzi2, MD; Sare Safi1, PhD 1Ophthalmic Epidemiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3Department of Stem Cells, Cell Science Research Center, Royan Institute, Tehran, Iran ORCID: Siamak Moradian: https://orcid.org/0000-0002-5328-7565 J Ophthalmic Vis Res 2021; 16 (1): 147–147 Dear Editor, We would like to thank Dr Arjun Srirampur for his interest in our work. Department of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Pasdaran Ave., Boostan 9 St., Tehran 16666, Iran. keywords: iran; tehran cache: jovr-8265.pdf plain text: jovr-8265.txt item: #224 of 284 id: jovr-9076 author: Yazdani, Shahin title: Editorial — Glaucomatous Optic Neuropathy: The Dark Side of the Moon date: 2021-04-29 words: 1607 flesch: 53 summary: This may reflect higher susceptibility of larger optic nerves to glaucomatous damage. J Ophthalmic Vis Res 2021;16:148–150. keywords: glaucoma; nerve; ophthalmol; optic; pressure cache: jovr-9076.pdf plain text: jovr-9076.txt item: #225 of 284 id: jovr-9077 author: Derakhshan, Akbar; Heravian, Javad; Abdolahian, Milad; Bamdad, Shahram title: Long-term Outcomes of Collagen Crosslinking for Early Keratoconus date: 2021-04-29 words: 3988 flesch: 53 summary: Treatment options available for increasing the visual acuity or/and halting the progression of keratoconus consist of spectacles, rigid gas permeable contact lenses,[1] collagen crosslinking,[2] intracorneal rings,[3] and keratoplasty.[4, 5] Corneal collagen crosslinking (CXL) has been introduced as a promising method for keratoconus management. Corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. keywords: collagen; corneal; crosslinking; follow; keratoconus; mean cache: jovr-9077.pdf plain text: jovr-9077.txt item: #226 of 284 id: jovr-9078 author: Karadag, Remzi; M. Hammersmith, Kristin ; K. Nagra, Parveen ; J. Rapuano, Christopher title: Anterior Chamber Characteristics, Endothelial Parameters, and Corneal Densitometry After Descemet Stripping Automated Endothelial Keratoplasty in Patients With Fuchs Dystrophy date: 2021-04-29 words: 3300 flesch: 54 summary: Corneal lamellar thickness measurements for DSAEK graft and recipient cornea were obtained using the measurement caliper provided by the software in all eight meridians and centrally. Although there were lower values in the anterior or middle corneal densitometry in DSAEK group, the differences were not statistically significant (P = 0.108 and P = 0.134, respectively) keywords: anterior; chamber; corneal; dsaek; endothelial; eye; group; keratoplasty; parameters cache: jovr-9078.pdf plain text: jovr-9078.txt item: #227 of 284 id: jovr-9079 author: Reza Talebnejad, Mohammad ; Azimi, Ali; Reza Khalili, Mohammad ; Meshksar, Aidin title: The Role of Trace Elements in Pseudoexfoliation Syndrome: A Cross-sectional Study date: 2021-04-29 words: 3617 flesch: 53 summary: BY KNOWLEDGE E 165 http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v16i2.9079&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR Trace Elements and Pseudoexfoliation Syndrome; Talebnejad et al the lens zonules, iris surface, corneal endothelium, trabecular meshwork, anterior hyaloid surface and less frequently on the posterior lens capsule and even intraocular lens.[1, 2] Due to the accumulation of pseudoexfoliative material in different visceral organs, PXF syndrome is known as a systemic disorder.[3] The prevalence of PXF syndrome varies (0.69–23%) with the region and the study design.[1–4] The etiology of PXF syndrome is not exactly known, but a multifactorial complex model including genetic inheritance combined with environmental factors, such as geographic location, UV exposure, and decreased serum and aqueous levels of antioxidants have been suggested as the contributing factors.[5–10] keywords: group; iron; levels; ophthalmol; patients; pseudoexfoliation; pxf; serum; study; syndrome; trace cache: jovr-9079.pdf plain text: jovr-9079.txt item: #228 of 284 id: jovr-9080 author: F. S. Cruz, Natasha ; S. Santos, Katia ; L. Matuoka, Mateus ; Kasahara, Niro title: Translaminar Pressure Difference and Ocular Perfusion Pressure in Glaucomatous Eyes with Different Optic Disc Sizes date: 2021-04-29 words: 4333 flesch: 58 summary: Conclusion: Glaucoma patients with larger optic discs have higher TLPD. There is evidence suggesting that large optic discs may be more susceptible to glaucoma than small discs.[10] Uncertainties regarding whether the TLPD and OPP differ according to the optic disc size and its influence in the glaucoma optic neuropathy exist. keywords: disc; glaucoma; icp; nerve; ophthalmol; opp; optic; patients; pressure; size; study; tlpd cache: jovr-9080.pdf plain text: jovr-9080.txt item: #229 of 284 id: jovr-9081 author: Banaee, Touka; Alwan, Shadan; Kellogg, Clint; Kornblau, Ilyse; El-Annan, Jaafar title: PRN Treatment of Neovascular AMD with Cycles of Three Monthly Injections date: 2021-04-29 words: 6978 flesch: 63 summary: PRN treatment of AMD with anti-VEGF drugs was first examined in the PrONTO study, which was not a controlled study, and reported visual results comparable to the results of MARINA and ANCHOR trials. 2 ± 85 9. 7 30 3 –9 9 7. 8 ± 3. 1 9. 2 33 4 –9 6 13 .6 ± 0. 1 Pr os pe ct iv e *A ll nu m be rs ar e in th e fo rm of M ea n ± SD un le ss st at ed ot he rw is e; † C ha ng es co m pa re d to ba se lin e. A A O ,A m er ic an A ca de m y of O ph th al m ol og y; A fl, afl ib er ce pt ;B ev ,b ev ac iz um ab ;C AT T, co m pa ris on of A M D tr ea tm en tt ria l; C M T, ce nt ra lm ac ul ar th ic kn es s; IQ R ,i nt er qu ar til e ra ng e; IR IS re gi st ry ,I nt el lig en tR es ea rc h in Si gh tr eg is tr y; IV A N ,i nh ib it V EG F in ag e- re la te d ch or oi da l ne ov as cu la riz at io n tr ia l; Pr O N TO ,p ro sp ec tiv e O C T im ag in g of pa tie nt s w ith ne ov as cu la rA M D tr ea te d w ith in tr ao cu la rr an ib iz um ab ;R an ,R an ib iz um ab JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 2, APRIL-JUNE 2021 183 PRN Treatment of Neovascular AMD with Cycles of Three Injections; Banaee et al keywords: age; degeneration; injections; letters; months; neovascular; patients; prn; ranibizumab; results; study; treatment; vision; year cache: jovr-9081.pdf plain text: jovr-9081.txt item: #230 of 284 id: jovr-9082 author: Kumawat, Devesh; K. Padhy, Srikanta ; Kumar, Vinod title: Clinical and Multimodal Imaging Features of Subretinal Drusenoid Deposits date: 2021-04-29 words: 3857 flesch: 55 summary: A case of mixed SDD. Retinal features in eyes with subretinal drusenoid deposits Parameters Number of eyes (%) SDD∗ eyes Fellow eyes (n = 10) Total (n = 35) Nodular type (n = 23) Reticular type (n = 2) Mixed type (n = 10) keywords: deposits; drusenoid; eyes; imaging; reticular; sdd; type cache: jovr-9082.pdf plain text: jovr-9082.txt item: #231 of 284 id: jovr-9083 author: Maryam Hosseini, Seyedeh ; Morrovatdar, Negar; Hemati, Armin; Dolatkhah, Mozghan; Bakhtiari, Elham; Mirfeizi, Zahra; Azimizadeh, Mahdieh title: Evaluation and Comparison of Choroidal Thickness in Patients with Behçet Disease with versus without Ocular Involvement date: 2021-04-29 words: 4089 flesch: 49 summary: Choroidal thickness was significantly increased in BD patients with ocular involvement; therefore, EDI-OCT could be a noninvasive test for evaluation of ocular involvement in patients with BD. In contrast, some studies contradicted our findings.[8] Coskun et al[14] demonstrated that the choroid was significantly thinner in the eyes of Behçet patients with active posterior uveitis compared to patients in remission and control healthy individuals after excluding patients with macular edema. keywords: behçet; disease; fag; involvement; patients; sfct; thickness; uveitis cache: jovr-9083.pdf plain text: jovr-9083.txt item: #232 of 284 id: jovr-9085 author: Abri Aghdam, Kaveh ; Asadi, Reza; Soltan Sanjari, Mostafa ; Sadeghi, Ali; Razavi, Meshkat title: Comparing Two Inferior Oblique Weakening Procedures: Disinsertion versus Myectomy date: 2021-04-29 words: 3939 flesch: 51 summary: However, the IO recession is preferred to disinsertion, myectomy, and myotomy by many surgeons because of the ability to achieve a graded response[3] and the lower risk of unpredictable reattachment of IO muscle to the sclera.[4] Some studies have supported IO disinsertion because of its simplicity, decreased risk of hemorrhage, and a similar success rate to other methods.[5–8] Akbari et al showed that IO disinsertion effectively corrected primary position vertical deviation of unilateral congenital superior oblique palsy patients as IO myectomy when preoperative vertical deviation was ≤15D.[18] keywords: disinsertion; group; iooa; muscle; myectomy; oblique; patients cache: jovr-9085.pdf plain text: jovr-9085.txt item: #233 of 284 id: jovr-9086 author: D. Anesi, Stephen ; Y. Chang, Peter ; Maleki, Arash; Stephenson, Andrew; Montieth, Alyssa; Filipowicz, Artur; Syeda, Sarah; Asgari, Soheila; Walsh, Marisa; Lynne Metzinger, Jamie ; Foster, C. Stephen title: Treatment of Noninfectious Retinal Vasculitis Using Subcutaneous Repository Corticotropin Injection date: 2021-04-29 words: 7737 flesch: 44 summary: Patients who did not show clinical or objective evidence on the assessment of improvement while taking therapy were rescued at 12 weeks; patients who showed worsening or concern for their condition prior to 12 weeks were also rescued with appropriate therapy at the discretion of the investigator. General side effects were minimally seen and tolerated by patients without causation alone for termination of study medication use. keywords: baseline; disease; eyes; patients; ppp; rci; study; therapy; treatment; vasculitis; visit; week cache: jovr-9086.pdf plain text: jovr-9086.txt item: #234 of 284 id: jovr-9087 author: Roshanshad, Amirhossein; Ali Ashraf, Mohammad; Roshanshad, Romina; Kharmandar, Ali; Alireza Zomorodian, Seyed ; Ashraf, Hossein title: Ocular Manifestations of Patients with Coronavirus Disease 2019: A Comprehensive Review date: 2021-04-29 words: 7859 flesch: 49 summary: Postmortem evaluation of COVID-19 patients detected no viral RNA in different anterior and posterior segments of the eyes. The inclusion criteria were original articles about the ocular manifestations of COVID-19 patients. keywords: april; case; conjunctival; conjunctivitis; coronavirus; cov-2; covid-19; covid-19 patients; disease; et al; eye; findings; infection; june; manifestations; nerve; ophthalmic; optic; palsy; patients; research; sars; studies; study; syndrome; vision cache: jovr-9087.pdf plain text: jovr-9087.txt item: #235 of 284 id: jovr-9088 author: Barroso, Francisco; Crispim Ribeiro, João ; P. Miranda, Eduardo title: Phosphodiesterase Type 5 Inhibitors and Visual Side Effects: A Narrative Review date: 2021-04-29 words: 5927 flesch: 52 summary: The patients had no other risk factors for dry eye, suggesting that SC use was possibly the main cause of keratitis in these patients.[8] Final statement recommendation Patients who will start chronic PDE5i use and have complaints of dry eye or who use contact lenses should be counseled about an increased risk of keratitis. Moreover, in a double-blind, randomized, placebo-controlled, crossover study, Grunwald et al[16] reported no significant acute changes on IOP after a single oral dose of SC l 100 mg in 15 subjects aged 63 ± 14 years with bilateral chronic open-angle glaucoma.[16] Dündar et al[26] also showed no change in IOP after the administration of a single oral dose of 50 mg SC to 14 healthy male volunteers tested immediately before and 1 hr after SC administration.[26] 254 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 2, APRIL-JUNE 2021 PDE5i and Ocular Side Effects; Barroso et al Final statement recommendation There is a lack of prospective randomized trials to determine whether there is a true causal association between PDE5i use and elevation of IOP leading to glaucoma development or deterioration. keywords: case; effects; eye; naion; neuropathy; occlusion; optic; patients; pde5i; pressure; review; sildenafil; use; vision cache: jovr-9088.pdf plain text: jovr-9088.txt item: #236 of 284 id: jovr-9089 author: Karimi, Saeed; Arabi, Amir; Shahraki, Toktam title: Alcohol and the Eye date: 2021-04-29 words: 6920 flesch: 50 summary: Types of alcohol consumptions according to “drinking patterns and their definitions alcohol research: current reviews”[1] Type of alcohol consumption Definition Low-risk drinking and alcohol use disorder No more than 3–4 drinks on any single day and no more than 7–14 drinks per week Moderate alcohol consumption Up to 1–2 drinks per day Binge drinking 4–5 drinks in a 2-hr time frame Heavy drinking Binge drinking on each of 5 or more days in the past 30 days manifested by blurry vision, visual hallucination, dense central scotoma, and decreased visual acuity. Saeed Karimi: http://orcid.org/0000-0002-3231-8414 Amir Arabi: http://orcid.org/0000-0002-6523-7733 Abstract In this article, we present a review of ocular conditions related to alcohol consumption. keywords: acute; alcohol; alcohol consumption; case; consumption; day; days; disease; drinking; effects; eye; glaucoma; klein; methanol; neuropathy; ocular; ophthalmol; optic; research; risk; studies; study; syndrome; vision; visual cache: jovr-9089.pdf plain text: jovr-9089.txt item: #237 of 284 id: jovr-9091 author: Anvari, Pasha; Ashrafkhorasani, Maryam; Habibi, Abbas; Ghasemi Falavarjani, Khalil title: Artifacts in Optical Coherence Tomography Angiography date: 2021-04-29 words: 7837 flesch: 46 summary: We found that the prevalence of OCTA image artifacts is fairly high. This study aimed to review the literature describing OCTA artifacts. keywords: angiography; anvari; artifacts; coherence; et al; eyes; images; internet; macular; motion; octa; ophthalmol; optical; projection; retinal; segmentation; tomography; tomography angiography; vessels cache: jovr-9091.pdf plain text: jovr-9091.txt item: #238 of 284 id: jovr-9092 author: Beatson, Bradley; Fernando Arevalo, J. title: From the Hypotheses to Clinical Evidence in Retinal Therapy date: 2021-04-29 words: 2430 flesch: 40 summary: Solomon SD, Chew E, Duh EJ, et al. JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 2, APRIL-JUNE 2021 289 Hypotheses to Clinical Evidence in Retinal Therapy; Beatson et al 2. keywords: ivb; pdr; progression; retinopathy; trd; vitrectomy cache: jovr-9092.pdf plain text: jovr-9092.txt item: #239 of 284 id: jovr-9093 author: Hassanpoor, Narges; Mirshahi, Ahmad; Reza Niyousha, Mohammad title: Photopigment Bleaching Phenomenon on Fluorescein Angiography in a Patient with Impending Central Retinal Vein Occlusion date: 2021-04-29 words: 1327 flesch: 41 summary: Narges Hassanpoor: http://orcid.org/0000-0001-8296-0918 Mohammad Reza Niyousha: http://orcid.org/0000-0002-1119-5902 Abstract Purpose: To present the second case of photopigment bleaching phenomenon in fluorescein angiography (FA) and the first case of this phenomenon due to impending central retinal vein occlusion (CRVO). Photopigment bleaching phenomenon was seen in the late-phase FA [Figure 2d]. keywords: bleaching; eye; phenomenon; photopigment; retinal cache: jovr-9093.pdf plain text: jovr-9093.txt item: #240 of 284 id: jovr-9094 author: Papasavvas, Ioannis; Jeannin, Bruno; Pierre Herbort, Carle title: When HIV Immunodeficiency and Heterochromia Confuse the Issue: Recurrent Zoster Uveitis Mistaken for Fuchs’ Uveitis date: 2021-04-29 words: 1984 flesch: 52 summary: The ophthalmologist, in presence of VZV pathology in patients under the age of 50, should function as a whistle blower in order not to miss an early diagnostic opportunity for HIV infection. As we suspected an immune deficiency to varicella- zoster virus or a more general immunodepression, we asked the patient to give us his consent to search for HIV infection. keywords: heterochromia; hiv; iris; patient; uveitis; zoster cache: jovr-9094.pdf plain text: jovr-9094.txt item: #241 of 284 id: jovr-9096 author: Chandra, Parijat; Kumar, Vinod; Takkar, Brijesh; Kumawat, Devesh title: Silicone Oil Opacification after Prolonged Intraocular Retention date: 2021-04-29 words: 865 flesch: 52 summary: Invest Ophthalmol Vis Sci 2013;54:3316. 3. Ciardella AP, Langton K, Chang S. Intra-ocular dispersion of perfluorocarbon liquids in silicone oil. 2. Spitzer M, de Vries JW, Herrmann A, Bartz-Schmidt K- U, Dammeier S. Clouding of intraocular silicone oil in the absence of emulsification. keywords: india; oil; silicone cache: jovr-9096.pdf plain text: jovr-9096.txt item: #242 of 284 id: jovr-9097 author: Deokinandan Nayak Shinkre, Noopur ; P.S. Usgaonkar, Ugam title: Cavernous Hemangioma of the Conjunctiva date: 2021-04-29 words: 817 flesch: 54 summary: How to cite this article: Noopur Deokinandan Nayak Shinkre, Ugam P.S. Usgaonkar. Photo Essay Cavernous Hemangioma of the Conjunctiva Noopur Deokinandan Nayak Shinkre, MD; Ugam P.S. Usgaonkar, MD Department of Ophthalmology, Goa Medical College, Goa, India ORCID: Noopur Deokinandan Nayak Shinkre: http://orcid.org/0000-0001-5503-2710 J Ophthalmic Vis Res 2021; 16 (2): 303–305 PRESENTATION A 23-year-old healthy male presented to our outpatient department with complaint of foreign body sensation and a painless, red mass on the nasal side of his right eye, which he had noticed approximately six months before. keywords: conjunctiva; lesion; shinkre cache: jovr-9097.pdf plain text: jovr-9097.txt item: #243 of 284 id: jovr-9100 author: Sánchez-Tabernero, Sara ; García-Alvarez, Ciro ; García-Lagarto, Elena ; A. Saornil, Maria title: Pigment Epithelium Macroadenoma Mimicking Iris or Ciliary Body Melanoma date: 2021-04-29 words: 569 flesch: 46 summary: Email: s.t.sara.g@gmail.com Received: 08-04-2020 Accepted: 28-09-2020 Access this article online Website: https://knepublishing.com/index.php/JOVR DOI: 10.18502/jovr.v16i2.9100 Histopathology was diagnostic of macroadenoma of iris pigment epithelium, although a ciliary body origin could not be excluded. Histopathology was diagnostic of macroadenoma of iris pigment epithelium, although a ciliary body origin could not be excluded. keywords: epithelium; iris; pigment cache: jovr-9100.pdf plain text: jovr-9100.txt item: #244 of 284 id: jovr-9102 author: Nilforushan, Naveed; Abolfathzadeh, Navid title: The Impact of the COVID-19 Pandemic on Ophthalmology Residency Training date: 2021-04-29 words: 1206 flesch: 38 summary: Attention should also be paid to necessary changes in the national curriculum of ophthalmology residency education, to prepare residents with non-surgical but fundamental skills such as crisis management and teamwork.[5] The impact of COVID-19 related lockdown on ophthalmology training programs in India – outcomes of a survey. keywords: covid-19; iran; ophthalmology; pandemic; training cache: jovr-9102.pdf plain text: jovr-9102.txt item: #245 of 284 id: jovr-9425 author: Hafezi, Farhad title: Editorial – Corneal Cross-linking for Keratoconus: Exploring the Issues Regarding Accelerated Protocols and Thin Corneas date: 2021-07-29 words: 1619 flesch: 44 summary: However, it was clear that thin cornea CXL significantly decreased the specular endothelial cell count by 8%, albeit without signs of endothelial trauma. Jacob S, Kumar DA, Agarwal A, Basu S, Sinha P, Agarwal A. Contact lens-assisted collagen cross-linking (CACXL): a new technique for cross-linking thin corneas. keywords: corneal; cross; cxl; linking; riboflavin cache: jovr-9425.pdf plain text: jovr-9425.txt item: #246 of 284 id: jovr-9427 author: S. Zaitoun, Ismail ; Sheibani, Nader title: Editorial – Hypoxic-Ischemic Encephalopathy: Impact on Retinal Neurovascular Integrity and Function date: 2021-07-29 words: 2088 flesch: 52 summary: These findings support the notion that the retina is a prime target of HI insult, and the severity of retinal damage is independent of the severity of brain damage. Of note, we found retinal damage after exposure to HI vary among individuals; some show mild to no damage, some show moderate injuries, and others show severe injuries. keywords: blood; brain; damage; exposure; hie; hypoxic; ischemic; neonatal; retina cache: jovr-9427.pdf plain text: jovr-9427.txt item: #247 of 284 id: jovr-9428 author: Galvão Bezerra, Raquel ; Lílian Fernandes de Sousa Meneghim, Roberta ; Roberto Padovani, Carlos ; Artioli Schellini, Silvana title: Diode Green Laser in the Lid Trichiasis Treatment date: 2021-07-29 words: 3336 flesch: 53 summary: Argon laser treatment for trichiasis. Argon laser treatment of trichiasis. keywords: argon; diode; laser; lashes; patients; rate; study; success; treatment; trichiasis cache: jovr-9428.pdf plain text: jovr-9428.txt item: #248 of 284 id: jovr-9430 author: M Salman, Abdelrahman ; R Darwish, Taym ; H Haddad, Yusra ; H Shabaan, Rafea ; Z Askar, Mohammad title: Accelerated versus Standard Corneal Cross-linking for Progressive Keratoconus in Syria date: 2021-07-29 words: 5861 flesch: 53 summary: Koch DD, Jenkins RB, Weikert MP, Yeu E, Wang L. Correcting astigmatism with toric intraocular lenses: effect of posterior corneal astigmatism. Aslani F, Khorrami-Nejad M, Aghazadeh Amiri M, Hashemian H, Askarizadeh F, Khosravi B. Characteristics of posterior corneal astigmatism in different stages of keratoconus. keywords: corneal; cxl; cxl group; group; keratoconus; mean; min; values cache: jovr-9430.pdf plain text: jovr-9430.txt item: #249 of 284 id: jovr-9431 author: Amir Mishan, Mohammad ; Balagholi, Sahar; Chamani, Tahereh; Feizi, Sepehr; Soheili, Zahra-Soheila; Rezaei Kanavi, Mozhgan title: Potential Effect of Human Platelet Lysate on in vitro Expansion of Human Corneal Endothelial Cells Compared with Y-27632 ROCK Inhibitor date: 2021-07-29 words: 4663 flesch: 56 summary: In this study, we compared the proliferative effect of human platelet lysate (HPL), as a xeno-free medium supplement, with Y-27632 Rho/rho-associated protein kinase (ROCK) inhibitor, as a well- known proliferative and adhesive agent for CECs, and fetal bovine serum (FBS) as the control, in the culture medium of human corneal endothelial cells (HCECs). Effect of amniotic fluid on the in vitro culture of human corneal endothelial cells. keywords: cells; corneal; endothelial; fbs; hcecs; hpl; human; inhibitor; iran; platelet; proliferation; research; rock; rock inhibitor; y-27632; y-27632 rock cache: jovr-9431.pdf plain text: jovr-9431.txt item: #250 of 284 id: jovr-9432 author: Kalra, Gagan; Ichhpujani, Parul; Thakur, Sahil; Sharma, Urvashi title: Ideal Illumination for Smartphone-based Trabeculectomy Bleb Photography date: 2021-07-29 words: 4723 flesch: 45 summary: Native camera app images: (A) Close, (B) Intermediate, (C) Distant with yellow pen torch; (D) Close, (E) Intermediate, (F) Distant with white pen torch; FiLMiC Pro app images: (G) Close, (H) Intermediate, (I) Distant with yellow pen torch; (J) Close, (K) Intermediate, (L) Distant with white pen torch. This is particularly relevant for bleb morphology assessment as these images may be reliably used for partial IBAGS classification or Wuerzburg classification of bleb morphology.[16–18] SNR measures of native app images in different illumination settings clearly reflect the decreasing illumination as introduction of image noise is evident when illumination distance increases. keywords: app; bleb; camera; close; filmic; illumination; images; intermediate; light; native; photography; smartphone; snr cache: jovr-9432.pdf plain text: jovr-9432.txt item: #251 of 284 id: jovr-9433 author: Power, Barry; Brady, Robert; Connell, Paul title: Analyzing the Carbon Footprint of an Intravitreal Injection date: 2021-07-29 words: 5348 flesch: 41 summary: Results: Carbon emissions associated with a single intravitreal injection, excluding the anti-VEGF agent, were 13.68 kg CO2eq. The omission of items considered dispensable from injection packs would reduce carbon emissions by an estimated 0.56 kg per injection – an annual saving of 3,360 kg CO2eq for our service. keywords: carbon; co2eq; conversion; emissions; footprint; injection; plastic; power; procurement; production; travel; use cache: jovr-9433.pdf plain text: jovr-9433.txt item: #252 of 284 id: jovr-9434 author: R. Starr, Matthew ; H. Ryan, Edwin ; Obeid, Anthony; Ryan, Claire; Gao, Xinxiao; L. Madhava, Malika ; M. Maloney, Sean ; Z. Adika, Adam ; V. Peddada, Krishi ; Sioufi, Kareem; G. Patel, Luv ; J. Ammar, Michael ; J. Forbes, Nora ; Capone Jr., Antonio ; G. Emerson, Geoffrey ; P. Joseph, Daniel ; Eliott, Dean; D. Regillo, Carl ; Hsu, Jason; P. Gupta, Omesh ; Yonekawa, Yoshihiro title: Scleral Buckling for Primary Retinal Detachment: Outcomes of Scleral Tunnels versus Scleral Sutures date: 2021-07-29 words: 4151 flesch: 48 summary: The selection largely depends on surgeon’s preference, and little data is available regarding comparative efficacy and outcomes.[3] Diplopia from strabismus following SB surgery is often temporary, but chronic or permanent strabismus may also occur and is a well-known complication, with a reported incidence between 5% and 25%.[4] Pre- and postoperative variables were evaluated including visual acuity, anatomic success, and postoperative strabismus. keywords: buckle; cohort; eyes; postoperative; scleral; strabismus; surgery; sutures; tunnels cache: jovr-9434.pdf plain text: jovr-9434.txt item: #253 of 284 id: jovr-9436 author: Görkem Çevik, Sadık ; Selim Bağlı, Bekir title: Change in the Foveal Avascular Zone and Macular Capillary Network Density after Hyperbaric Oxygen Therapy in Healthy Retina date: 2021-07-29 words: 3396 flesch: 55 summary: Laser Doppler velocimetry study of the effect of pure oxygen breathing on retinal blood flow. Retinal blood flow response to hyperoxia measured with en face doppler optical coherence tomography. keywords: blood; changes; density; flow; hbo2; mm−1; oxygen; right; therapy cache: jovr-9436.pdf plain text: jovr-9436.txt item: #254 of 284 id: jovr-9437 author: H Narnaware, Shilpi ; K Bawankule, Prashant ; Raje, Dhananjay title: Aggressive Posterior Retinopathy of Prematurity (APROP): LASER as the Primary Modality of Treatment date: 2021-07-29 words: 4253 flesch: 56 summary: Few studies have 404 JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 3, JULY-SEPTEMBER 2021 ROP in the Anti-VEGF Era; Narnaware et al shown delay in growth and pulmonary dysplasia in bevacizumab-treated babies.[29] A study by Morin et al reported that severe neurodevelopmental disabilities (Bayley scores <70) was seen 3.1 times higher with bevacizumab compared to laser.[30] Most recently, hypotension-related reports[31] and histopathologically proven new or reactivation of bronchopulmonary dysplasia have been noted after anti-VEGF administration.[32] Few studies were designed to study specific abnormalities related to anti-VEGF treatment and detected no systemic complications.[29, 33, 34] BY KNOWLEDGE E http://crossmark.crossref.org/dialog/?doi=10.18502/jovr.v16i3.9437&domain=pdf&date_stamp=2019-07-17 https://knepublishing.com/index.php/JOVR ROP in the Anti-VEGF Era; Narnaware et al Many previous studies have shown more unfavorable outcomes in APROP (ranging from 15% to 29%) undergoing laser treatment compared with anti-vascular endothelial growth factor (anti- VEGF) keywords: aprop; babies; bevacizumab; eyes; laser; pma; prematurity; retinopathy; study; treatment; weeks cache: jovr-9437.pdf plain text: jovr-9437.txt item: #255 of 284 id: jovr-9438 author: Hassanpour, Kiana; Nourinia, Ramin; Gerami, Ebrahim; Mahmoudi, Ghavam; Esfandiari, Hamed title: Ocular Manifestations of the Sturge–Weber Syndrome date: 2021-07-29 words: 9893 flesch: 51 summary: The effect of oral propranolol on intraocular pressure in infants with Sturge–Weber syndrome glaucoma. Mobile lens-induced angle closure glaucoma and rubeosis iridis in Sturge Weber syndrome. keywords: angle; diffuse; et al; eyes; glaucoma; hemangioma; iop; mean; months; onset; onset glaucoma; ophthalmol; patients; range; retinal; sturge; sturge weber; success; surgery; sws; sws glaucoma; trabeculectomy; treatment; vascular; weber syndrome; years cache: jovr-9438.pdf plain text: jovr-9438.txt item: #256 of 284 id: jovr-9440 author: Ebrahimiadib, Nazanin; Berijani, Sahar; Ghahari, Mohammadreza; Golsoorat Pahlaviani, Fatemeh title: Ankylosing Spondylitis date: 2021-07-29 words: 4851 flesch: 39 summary: Patients may also present with constitutional symptoms including low grade fever, anorexia, fatigue, and weight loss.[2] Ocular Manifestations Acute anterior uveitis is the most common non- articular manifestation of AS and presents in up to 30% of patients during the course of the disease and may increase to 50% with longer follow-up.[4] Uveitis is most often characterized by recurrent, asymmetric and bilateral iridocyclitis, involving only one eye at a time and is not related to the severity and course of joint involvement.[17] The interval between attacks is highly variable and can range from one month to 35 years, although most commonly they occur between 14 and 25 months.[4] Common forms of anterior uveitis in AS are iritis (with inflammatory cells in the anterior chamber and no involvement of the anterior vitreous), iridocyclitis (primary inflammation of the iris and secondary inflammation of the ciliary body; inflammatory cells present in both the anterior chamber and anterior vitreous), and cyclitis (inflammation of mainly the ciliary body).[2] Patients typically present with sudden ocular pain, redness, photophobia, and decreased vision.[20] The main findings on examination are limbal injection, fine whitish–gray keratic precipitates, moderate to severe amounts of cells which may sometimes cause hypopyon and fibrinous exudate in the anterior chamber.[5] Inflammatory cells in the anterior chamber of patients with AS are more static in nature. keywords: acute; b27; diagnosis; disease; hla; inflammation; joint; patients; spondylitis; spondyloarthropathies; tnf; treatment; uveitis cache: jovr-9440.pdf plain text: jovr-9440.txt item: #257 of 284 id: jovr-9441 author: Bagheri, Abbas; Shahraki, Kourosh; Arabi, Amir; Bahmani Kashkouli, Mohsen title: Normal Exophthalmometry Values in Iranian Population: A Meta-analysis: A complete translation from Farsi date: 2021-07-29 words: 4042 flesch: 56 summary: Normal eye protrusion values from the included studies* Study/age groups (yr) Bagheri et al[13] (2007) Comparison of normal eye protrusion values in different ethnic groups Study Geographic area No. keywords: eye; eye protrusion; iranian; mean; population; protrusion; study; values; women cache: jovr-9441.pdf plain text: jovr-9441.txt item: #258 of 284 id: jovr-9442 author: Kamalipour, Alireza; Moghimi, Sasan title: Macular Optical Coherence Tomography Imaging in Glaucoma date: 2021-07-29 words: 7535 flesch: 51 summary: In addition, macular OCT measurements have shown high reproducibility in advanced disease, good correlation with VF sensitivity measures, and preserved dynamic range at a stage when the reliability of VF tests decline. Based on these findings, they suggested that macular OCT is capable of identifying early glaucomatous damages that may not be apparent on OCT scans of the disc area.[35] Another useful sign for the diagnosis of early glaucoma in macular OCT is the presence of temporal horizontal raphe on GCIPL deviation maps [Figure 1A]. keywords: cell; coherence; detection; eyes; ganglion; gcipl; glaucoma; kim; layer; macular; oct; ophthalmol; patients; progression; sci; thickness; tomography; vis cache: jovr-9442.pdf plain text: jovr-9442.txt item: #259 of 284 id: jovr-9448 author: R. Starr, Matthew ; J. Bakri, Sophie title: The Use of Tutoplast as an Adjunct in Scleral Buckle Procedure in Patients with Extremely Thin Sclera date: 2021-07-29 words: 1382 flesch: 54 summary: All patients had Tutoplast Pericardial Graft placed over the areas of thin sclera which allowed the scleral buckle to be sutured onto the Tutoplast rather than the thin sclera. In all patients, Tutoplast Pericardial Graft was placed over the areas of thin sclera in order to facilitate the placement of the scleral buckle. keywords: buckle; patients; sclera; tutoplast cache: jovr-9448.pdf plain text: jovr-9448.txt item: #260 of 284 id: jovr-9449 author: K. Bober, Natalia ; Kumaran, Neruban; H Williamson, Tom title: Outcomes Following Pars Plana Vitrectomy for Severe Ocular Trauma date: 2021-07-29 words: 4091 flesch: 48 summary: Furthermore, there was a wide variation of one to five surgeries required for patients with ocular trauma in our cohort, with a mean of 1.8 (±1.0) operations similar to other cohorts.[16] Furthermore, we identified that presenting VA (p < 0.01) and type of ocular injury (p = 0.05) as prognostic indicators for final VA again suggesting that those with less severe injuries on presentation have a better prognosis. We identified assault and contusion injuries to be the most common mode and type of ocular injury in our cohort. keywords: acuity; betts; injuries; injury; logmar; patients; trauma; visual cache: jovr-9449.pdf plain text: jovr-9449.txt item: #261 of 284 id: jovr-9450 author: Pigatto, Paolo; Guzzi, Gianpaolo title: Bilateral Optic Disc Edema in a Patient with Lead Poisoning date: 2021-07-29 words: 888 flesch: 52 summary: Fortunately, Pb poisoning is a rare circumstance not commonly encountered by ophthalmologists.[8–11] Consistent with this notion, Pb and other toxic metals (i.e., organic mercury, thallium) are to be considered “neurotoxicants”, primarily due to toxic effects on the optic nerve.[12–14] With regard to the issue of toxic optic neuropathy, over the past two decades, we have noticed only one case in which papilledema was associated with overexposure to nickel salts. E-mail: gianpaolo_guzzi@fastwebnet.it Received: 13-02-2021 Accepted: 13-04-2021 Access this article online Website: https://knepublishing.com/index.php/JOVR DOI: 10.18502/jovr.v16i3.9450 In toxicology, the whole-blood Pb concentrations have been used in conjunction with urinary Pb levels as a primary measure of Pb exposure in humans.[6] Toxicological studies suggest that exposure to Pb during developmental periods may lead to long- term visual deficits both in in vitro and in animal models.[7] Toxic optic neuropathy may be the unique clinically significant alteration in patients with Pb poisoning.[2, 3] keywords: lead; optic; poisoning cache: jovr-9450.pdf plain text: jovr-9450.txt item: #262 of 284 id: jovr-9451 author: Abri Aghdam, Kaveh ; Zand, Amin; Soltan Sanjari, Mostafa title: Authors' Reply to Bilateral Optic Disc Edema in a Patient with Lead Poisoning date: 2021-07-29 words: 503 flesch: 55 summary: 3. Pigatto PD, Ronchi A, Guzzi G. Iron overload, G6PD deficiency, and lead levels on blood smears. Letter Authors’ Reply Kaveh Abri Aghdam, MD, PhD; Amin Zand, MD; Mostafa Soltan Sanjari, MD Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran J Ophthalmic Vis Res 2021; 16 (3): 526–526 Dear Editor, We sincerely thank Dr Guzzi for the interest in our case report[1] and would like to take this opportunity to make some clarifications as follows: The main concern raised by Dr Guzzi was that serum lead level alone does not adequately reflect the total body burden of the lead and the whole-blood lead level in conjugation with its urinary levels is a primary measure of lead exposure in humans.[2–4] We fully agree with Dr Guzzi based on the available literature on this subject. keywords: guzzi; lead cache: jovr-9451.pdf plain text: jovr-9451.txt item: #263 of 284 id: jovr-9740 author: Abtahi, Seyed-Hossein; Nouri, Hosein; Moradian, Siamak; Yazdani, Shahin; Ahmadieh, Hamid title: Editorial – Eye Disorders in the Post-COVID Era date: 2021-10-25 words: 2062 flesch: 46 summary: Multi-center surveys are warranted to determine if such risks are significant enough to be prospectively investigated among hospitalized COVID-19 survivors. The postponement of in-person follow-up visits and replacement with tele/virtual visits may predispose to delayed or wrong diagnoses and lead to insufficient treatment.[8] Most hospitalized COVID-19 patients receive systemic corticosteroids to alleviate systemic inflammation and prevent pulmonary fibrosis; dexamethasone is widely administered and has been shown to reduce mortality in patients receiving oxygen support or mechanical ventilation.[9] keywords: covid-19; glaucoma; ophthalmic; pandemic; patients; research; risk; steroid cache: jovr-9740.pdf plain text: jovr-9740.txt item: #264 of 284 id: jovr-9742 author: Mahjoob, Monireh; Heydarian, Samira title: Effect of Contact Lenses on Contrast Sensitivity under Various Lighting Conditions date: 2021-10-25 words: 3680 flesch: 52 summary: This unchanged glare sensitivity has been noted in colored contact lenses as well.[25] Another study showed that while soft contact lenses do not affect glare disability, they can induce glare effects.[26] Since placing an additional optical surface such as a contact lens can augment the amount of light scattering and absorption, it is plausible to observe a decline in CS under different lighting conditions when contact lenses are worn. The greater corneal edema in colored contact lenses compared to clear lenses was not a possible cause in their study and it was stated that the main reason for this difference was the lower optical quality of colored lenses compared to clear ones.[16] Other studies suggested that the diameter of pigment- free optical zone in colored contact lenses plays a substantial role in aberrations, visual acuity, and CS; aberrations and CS in colored contact lenses with an optical diameter of 6 mm do not differ from those of clear contact lenses. keywords: clear; conditions; contact; contrast; eye; glare; lenses; lighting; sensitivity cache: jovr-9742.pdf plain text: jovr-9742.txt item: #265 of 284 id: jovr-9743 author: Le, Peter B.; Chen, Fang; Myung, David title: A Simple Inner-Stopper Guarded Trephine for Creation of Uniform Keratectomy Wounds in Rodents date: 2021-10-25 words: 4000 flesch: 57 summary: The linear dependence was considered weak when the Pearson’s r value is below 0.2. JOURNAL OF OPHTHALMIC AND VISION RESEARCH VOLUME 16, ISSUE 4, OCTOBER-DECEMBER 2021 549 New Trephine for Rodent Studies; Le et al Figure 4. Comparison of corneal defects created by the inner-stopper guarded trephine by two users with different keratectomy experiences. In situ-forming collagen hydrogel crosslinked via multi-functional PEG as a matrix therapy for corneal defects. keywords: cornea; defect; healing; keratectomy; rat; rats; stopper; studies; trephine; wound cache: jovr-9743.pdf plain text: jovr-9743.txt item: #266 of 284 id: jovr-9744 author: Mehdi Soltan Dallal, Mohammad ; Nikkhahi, Farhad; Mostafa Imeni, Seyed ; Molaei, Saber; Kazem Hosseini, Seyed ; Kalafi, Zohreh; Sharifi Yazdi, Sara ; Molla Agha Mirzaei, Hedroosha title: Amniotic Membrane Transplantation for Persistent Epithelial Defects and Ulceration due to Pseudomonas Keratitis in a Rabbit Model date: 2021-10-25 words: 3529 flesch: 43 summary: Evaluation of amniotic membrane transplantation as an adjunct to medical therapy as compared with medical therapy alone in acute ocular burns. Amniotic membrane transplantation for persistent corneal ulcers and perforations in acute fungal keratitis. keywords: amniotic; amt; average; ciprofloxacin; control; group; infiltration; keratitis; membrane; research; tehran; transplantation cache: jovr-9744.pdf plain text: jovr-9744.txt item: #267 of 284 id: jovr-9745 author: Meteoukki, Wafaa; Fodil, Mostefa; Adda Negaz, Nawel ; Rahmoun, Nesrine; Lardjam Hetraf, Sarah ; Ouhaibi Djellouli, Hadjira ; Djelti Messal, Ahlem ; Abdi, Meriem; Samia Aberkane, Meriem ; Chiali, Abdelillah; Derdour, Amine; Idder, Aicha; Zemani-Fodil, Faouzia title: Association of IL4 rs2070874, FoxP3 rs3761548 Polymorphisms with Keratoconus in Algeria date: 2021-10-25 words: 5245 flesch: 55 summary: The comparison of quantitative variants between KC patients and control group, the frequencies of the allele and genotype were analyzed using the Pearson’s Chi-square (χ2) test. The mean age of KC patients was 30.40 ± 11.33 (range 6–70 years), while the mean age of the healthy group was 30.14 ± 9.29 (range, 19–62 years), there was no statically significant difference in the mean age between the two groups. keywords: algeria; allele; association; controls; eye; foxp3; il4; keratoconus; patients; polymorphisms; risk; rs2070874; rs3761548; study; table cache: jovr-9745.pdf plain text: jovr-9745.txt item: #268 of 284 id: jovr-9746 author: Azaripour, Ebrahim; Khakpour, Yaser; Soltani-Moghadam, Reza ; Moravvej, Zahra; Medghalchi, Abdolreza; Behboudi, Hassan; Alizadeh, Yousef; Soltanipour, Soheil; Kianmehr, Shila title: Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma date: 2021-10-25 words: 4255 flesch: 49 summary: The mean postoperative IOP reduced significantly in both groups, although the mean IOP reduction was significantly greater in PEXG eyes (14.7 ± 8.9 vs 10.1 ± 7.7 mmHg) Owing to its pathophysiology, PEXG eyes are more prone to trabeculectomy-related complications.[17, 18] keywords: eyes; follow; glaucoma; iop; patients; pexg; poag; study; success; viscocanalostomy cache: jovr-9746.pdf plain text: jovr-9746.txt item: #269 of 284 id: jovr-9747 author: Heshmati, Ali; Taghizadeh, Peyman; Ahmadieh, Hamid; Yaseri, Mehdi; Suri, Fatemeh; Alizadeh, Mahsa; Dadashzadeh, Marjan; Khatami, Hajar; Moradkhah Navi, Monireh ; Zamanparvar, Parisa; Behboudi, Hassan; Elahi, Elahe title: Carrier Status for p.Gly61Glu and p.Arg368His CYP1B1 Mutations Causing Primary Congenital Glaucoma in Iran date: 2021-10-25 words: 4702 flesch: 51 summary: Original Article Carrier Status for p.Gly61Glu and p.Arg368His CYP1B1 Mutations Causing Primary Congenital Glaucoma in Iran Ali Heshmati1a, MS; Peyman Taghizadeh1a, MS; Hamid Ahmadieh2, MD; Mehdi Yaseri3, PhD Fatemeh Suri2, PhD; Mahsa Alizadeh4, Marjan Dadashzadeh5, Hajar Khatami6, MSc Monireh Moradkhah Navi7, Parisa Zamanparvar8, Hassan Behboudi9*, MD; Elahe Elahi1*, PhD 1School of Biology, University College of Science, University of Tehran, Tehran, Iran 2Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 4Astaneh Health Center, Astaneh, Guilan, Iran 5Rasht Health Center, Rasht, Guilan, Iran 6Anzali Health Center, Anzali, Guilan, Iran 7Talesh Medical Center, Talesh, Guilan, Iran 8Lahijan Medical Center, Lahijan, Guilan, Iran 9Department of Ophthalmology, Guilan University of Medical Sciences, Rasht, Iran aThese two authors contributed equally ORCID: Elahe Elahi: http://orcid.org/0000-0002-6897-2223 Abstract Purpose: To estimate carrier frequencies of CYP1B1 mutations p.Gly61Glu and p.Arg368His, respectively, in Talesh and the east of Guilan province in Iran with a maximum error of 2%. The need for screening of the p.Gly61Glu and p.Arg368His mutations before marriage in the respective regions should be considered. keywords: carriers; cyp1b1; east; frequency; glaucoma; guilan; individuals; iran; mutation; p.arg368his; p.gly61glu; pcg; talesh cache: jovr-9747.pdf plain text: jovr-9747.txt item: #270 of 284 id: jovr-9748 author: Juliano, Joseph; Patel, Sagar; Ameri, Hossein title: Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid date: 2021-10-25 words: 5840 flesch: 54 summary: Given the characteristic appearance for vitelliform lesion, the lesion was observed without injection. In vitelliform lesions, the pigment is located centrally and surrounded by a hypopigmented halo. keywords: amd; avmd; eye; eyes; follow; lesion; patient; srf; vitelliform cache: jovr-9748.pdf plain text: jovr-9748.txt item: #271 of 284 id: jovr-9749 author: Abrishami, Mojtaba; Daneshvar, Ramin; Emamverdian, Zahra; Shoeibi, Nasser; Sedighi, Shima; Saeidi Rezvani, Talieh ; Saeedian, Neda; Eslami, Saeid title: Optic Nerve Head Optical Coherence Tomography Angiography Findings after Coronavirus Disease date: 2021-10-25 words: 6055 flesch: 51 summary: Comparison of all vessels (AV), including both small and large vessels, vessel density (VD) of COVID-19 patients eyes versus normal eyes COVID-19 patients eyes Mean ±±± SD (Range) Comparison of all vessels (AV), including both small and large vessels, vessel density (VD) of hospitalized versus non- hospitalized/outpatients treated COVID-19 patients Non-hospitalized (n = 16) Mean ±±± SD (Range) Hospitalized (n = 9) Mean ±±± SD (Range) P-value Whole Image – AV VD 48.58 ± 4.83 (33.40–56.30) 47.92 ± 4.28 (41.90–55.30) 0.725 Inside Disc – AV VD 49.54 ± 4.86 (31.90–56.40) 48.12 ± 3.95 (41.80–54.90) 0.444 keywords: covid-19; disc; disease; inferior; octa; onh; patients; peripapillary; study; sv vd cache: jovr-9749.pdf plain text: jovr-9749.txt item: #272 of 284 id: jovr-9750 author: Mirrahimi, Mehraban; Safi, Sare; Mohammadzadeh, Maryam; Doozandeh, Azadeh; Suri, Fatemeh title: Variable Expressivity of Wolfram Syndrome in a Family with Multiple Affected Subjects date: 2021-10-25 words: 3510 flesch: 50 summary: Although the medical findings and clinical examination are imperative for the diagnosis of Wolfram syndrome, genetic testing is useful to confirm the diagnosis, especially in cases with possible reduced penetrance of the characteristic signs. Wolfram syndrome (WFS) also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, deafness) is a progressive neurodegenerative disease affecting multiorgan systems.[1] keywords: figure; gene; loss; ophthalmic; research; syndrome; wfs1; wolfram cache: jovr-9750.pdf plain text: jovr-9750.txt item: #273 of 284 id: jovr-9751 author: Vatankhah, Roya; Emadzadeh, Ali; Nekooei, Sirous; Tafaghodi Yousefi, Bahar ; Khadem Rezaiyan, Majid ; Karimi Moonaghi, Hossein ; Etezad Razavi, Mohammad title: 3D Printed Models for Teaching Orbital Anatomy, Anomalies and Fractures date: 2021-10-25 words: 3876 flesch: 42 summary: The educational booklets were distributed, and various forms of orbital 3D models were printed from orbital computed tomography (CT) scans. The purpose of this study was to determine the impact on learning of ophthalmology residents using 3D printing models from orbital CT scans. keywords: education; group; intervention; learning; mashhad; medical; models; residents; study cache: jovr-9751.pdf plain text: jovr-9751.txt item: #274 of 284 id: jovr-9753 author: Rafaela Moreira Gomes, Jessica ; Maria de Braga Franco, Sandra title: Near Vision Tasks and Optical Quality of the Eye date: 2021-10-25 words: 7762 flesch: 61 summary: Several studies found a transient myopia caused by near vision work, between –0.12 D and – 1.30 D.[13–15] Resolution of symptoms occurs 30/60 min after completing the task in symptomatic subjects.[16, 17] It has been suggested that the eyelid forces, during near vision tasks, causes significant changes in eye aberrations.[18] Buehren et al noted that there was an increase in ocular high-order aberrations (HOA) following a 2-hr reading task which was more significant in myopic subjects and in eyes with large pupil diameters (4 and 5 mm).[19] The changes in ocular aberrations depend also on the requirements of the tasks. The recent study of Jimánez et al found a higher increase in RMS astigmatism when subjects performed a task with higher-cognitive demands which persisted 10 min after completing the task.[20] Previous studies showed that ocular aberrations change significantly with accommodation and the RMS of ocular low-order aberrations (LOA) and keywords: aberrations; changes; computer; corneal; eye; group; ocular; paper; quality; subjects; task; vision cache: jovr-9753.pdf plain text: jovr-9753.txt item: #275 of 284 id: jovr-9754 author: Hardianti Gunardi, Triana ; Paramita Susantono, Diannisa ; Arus Victor, Andi ; Sitompul, Ratna title: Atopobiosis and Dysbiosis in Ocular Diseases: Is Fecal Microbiota Transplant and Probiotics a Promising Solution? date: 2021-10-25 words: 7327 flesch: 34 summary: 3. Kalyana Chakravarthy S, Jayasudha R, Sai Prashanthi G, Ali MH, Sharma S, Tyagi M, et al. Gaboriau-Routhiau V, Rakotobe S, Lécuyer E, Mulder I, Lan A, Bridonneau C, et al. keywords: atopobiosis; bacteria; barrier; cells; diseases; dysbiosis; et al; eye; fecal; fmt; gut; gut microbiome; human; mice; microbiome; numbers; patients; probiotics; role; specific; studies; uveitis cache: jovr-9754.pdf plain text: jovr-9754.txt item: #276 of 284 id: jovr-9755 author: Torabi, Rana; Harris, Alon; Siesky, Brent; Zukerman, Ryan; Oddone, Francesco; Mathew, Sunu; Januleviciene, Ingrida; Verticchio Vercellin, Alice C. title: Prevalence Rates and Risk Factors for Primary Open Angle Glaucoma in the Middle East date: 2021-10-25 words: 7763 flesch: 56 summary: Studies of ME glaucoma risk factors that identify chromosomes, familial trend, age/gender, socioeconomic status, lifestyle, intraocular pressure, vascular influences, optic disc hemorrhage, cup-to-disc ratio, blood pressure, obstructive sleep apnea, and diabetes mellitus were included in this systematic review. At this time, however, there are only isolated studies looking at specific chromosomal factors and their relationship to glaucoma prevalence or its pathogenesis. keywords: angle; angle glaucoma; association; data; disc; east; et al; factors; glaucoma; middle; ophthalmol; patients; poag; population; prevalence; primary; rates; risk; saudi; studies; study cache: jovr-9755.pdf plain text: jovr-9755.txt item: #277 of 284 id: jovr-9756 author: Abdi, Fatemeh; Mohammadi, S. Saeed; Ghasemi Falavarjani, Khalil title: Intravitreal Methotrexate date: 2021-10-25 words: 9291 flesch: 42 summary: Benner et al[74] treated five eyes with severe PVR and recurrent retinal detachment using relaxing retinectomy, extended perfluorocarbon liquid tamponade for four weeks, and a series of intravitreal MTX injections (100– 200 μg) every two weeks. Progression of preexisting cataract is also noted as a side effect of intravitreal MTX injection, however, the majority of evaluated patients were vitrectomized that predisposed the eyes to the progression of cataract.[39] Band keratopathy and iris and anterior chamber angle neovascularization with subsequent neovascular glaucoma were also reported as a rare complications of intravitreal injection of MTX.[29] Choudhury et al reported two patients, one having idiopathic retinal vasculitis and the other having pars planitis in association with CME who received intravitreal injection of MTX. keywords: acuity; cell; detachment; effect; eyes; inflammation; injection; intraocular; intravitreal; lymphoma; macular; methotrexate; months; mtx; ophthalmol; patients; proliferative; pvr; research; study; systemic; treatment; uveitis; vision; vitreous; weeks; µg mtx cache: jovr-9756.pdf plain text: jovr-9756.txt item: #278 of 284 id: jovr-9757 author: Motevasseli, Tahmineh; Mohammadi, Saeed; Abdi, Fatemeh; Freeman, William R. title: Side Effects of Brolucizumab date: 2021-10-25 words: 3852 flesch: 37 summary: Unlike the HAWK and HARRIER studies which reported the incidence of retinal vasculitis with retinal vascular occlusion 2.1%, it was recently reported to be 4.6 per 10,000 injections in the post-marketing surveillance.[28] This difference might be due to difference in recruited population who were treatment naïve in the phase-III clinical trial, since patients who were previously treated with anti-VEGF drugs were more susceptible to IOI. Cox JT, Eliott D, Sobrin L. Inflammatory complications of intravitreal anti-VEGF injections. keywords: brolucizumab; effects; eye; injection; intravitreal; ioi; patients; vasculitis; vegf; vision cache: jovr-9757.pdf plain text: jovr-9757.txt item: #279 of 284 id: jovr-9758 author: Pramil, Varsha; Moult, Eric M.; Fujimoto, James G.; Waheed, Nadia K. title: OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age Related Macular Degeneration date: 2021-10-25 words: 3963 flesch: 44 summary: Artifacts in OCTA choriocapillaris imaging can also arise through processing and analysis steps. Additionally, choriocapillaris flow impairment have also been reported to be larger throughout the macula in patients with neovascular AMD compared to age- matched controls.[18, 19] More recently, researchers have used OCTA to quantitatively analyze the spatial distribution of choriocapillaris impairment surrounding CNV lesions. keywords: age; amd; angiography; choriocapillaris; coherence; degeneration; flow; imaging; neovascular; octa; ophthalmol; optical cache: jovr-9758.pdf plain text: jovr-9758.txt item: #280 of 284 id: jovr-9759 author: Taher Rajabi, Mohammad ; Cheraqpour, Kasra; Mohammadi, S. Saeed; Veshagh, Mohammad; Zahra Poursayed Lazarjani, Seyedeh ; Hosseinzadeh, Farideh; Asadi Amoli, Fahimeh ; Hosseini, Simindokht title: Isolated Intraconal Meningioma date: 2021-10-25 words: 2755 flesch: 37 summary: Conclusion: Ectopic orbital meningiomas are rare tumors that are not easily diagnosed without postoperative histopathology. The last rare group is ectopic meningiomas which are free from any connections to the optic nerve or intracranial meninges (<1%).[2–9] Ectopic orbital meningioma is usually located on the medial part of the orbit.[10] This uncommon entity of meningiomas usually reveals as a well-circumscribed mass but an ill-defined border does not rule out this type of tumor.[10] Herein, we report a rare case of ectopic (isolated) intraconal meningioma. keywords: ectopic; images; mass; meningioma; months; mri; proptosis; signals cache: jovr-9759.pdf plain text: jovr-9759.txt item: #281 of 284 id: jovr-9760 author: Singh, Manpreet; Singh Jassi, Amandeep ; Kaur, Manpreet; Gupta, Pankaj title: Complete Traumatic Luxation of the Eyeball date: 2021-10-25 words: 1309 flesch: 44 summary: (a) Axial scan illustrates left orbital fractures, pneumo-orbit, lost eyeball with transected medial rectus (yellow arrow), and optic nerve (black arrow). The joint management of luxated eyeball cases by ophthalmologists, maxillo-facial surgeons, and neurosurgeons provides a holistic approach in achieving the best possible cosmetic and functional outcomes. keywords: eyeball; luxation; muscle; ophthalmic cache: jovr-9760.pdf plain text: jovr-9760.txt item: #282 of 284 id: jovr-9761 author: Jafarinasab, Mohammad-Reza; Hadi, Yasaman; Espandar, Goldis title: Femtosecond Laser-assisted Allogenic Additive Stromal Keratoplasty with or without Excimer Laser Donor Keratomileusis for Management of Keratoconus date: 2021-10-25 words: 3707 flesch: 50 summary: Corneal lenticule allotransplantation after femtosecond laser small incision lenticule extraction in rabbits. Clinically, we noted no significant difference in terms of patient satisfaction regarding corrected visual acuity between subjects who received refractive corrected lenticules and those who received a non-modified lenticule [Table 2]. Biological inlays, proposed in the current pilot study, theoretically offer superior permeability and biocompatibility as compared to synthetic inlays. keywords: allogenic; corneal; donor; eye; fask; keratoconus; laser; lenticule; patients; pocket; stromal cache: jovr-9761.pdf plain text: jovr-9761.txt item: #283 of 284 id: jovr-9762 author: Sadoughi, Mohammad-Mehdi; Ahmady, Soleiman; Kalantarion, Masomeh; Khajeali, Nasrin title: Transforming Ophthalmology Training via Mobile Learning during the COVID-19 Pandemic date: 2021-10-25 words: 1004 flesch: 38 summary: One of the pioneering strategies that played a vital role during this pandemic is mobile learning. Other inherent advantages of mobile learning are that it is ubiquitous, portable, hybrid, interactive, and coordinative. keywords: education; learning; medical; mobile; ophthalmology cache: jovr-9762.pdf plain text: jovr-9762.txt item: #284 of 284 id: jovr-9763 author: Mohammadi, Seyed-Farzad; Ashrafi, Elham; Mohazzab-Torabi, Saman ; Delshad-Aghdam, Hanieh ; Katibeh, Marzieh title: Cataract Surgical Coverage in Kurdistan, Iran date: 2021-10-25 words: 1035 flesch: 54 summary: Profile of cataract surgery in Varamin Iran: a population-based study. Cataract surgery coverage was 90% in males and 89% in females (P = 0.91). keywords: cataract; coverage; iran; surgery cache: jovr-9763.pdf plain text: jovr-9763.txt