Jurnal Farmasi Sains dan Komunitas Vol. 19, No.2, November 2022 Editor in Chief Florentinus Dika Octa Riswanto Faculty of Pharmacy Universitas Sanata Dharma, Campus III Paingan, Maguwoharjo, Depok, Yogyakarta 55282, Indonesia; Email: dikaocta@usd.ac.id Vice Editor in Chief Dita Maria Virginia, Universitas Sanata Dharma, Indonesia Advisory Editorial Board Enade Perdana Istyastono, Universitas Sanata Dharma, Indonesia Dewi Setyaningsih, Universitas Sanata Dharma, Indonesia Fenty, Universitas Sanata Dharma, Indonesia Yosef Wijoyo, Universitas Sanata Dharma, Indonesia Phebe Hendra, Universitas Sanata Dharma, Indonesia Editorial Board Bandana Saini, University of Sydney, Australia P.T. Thomas, Taylor’s University, Malaysia Phayom Sookaneknun, Mahasarakham University, Thailand Monet M. Loquias, University of the Philippines, Philippines Yashwant Pathak, University of South Florida, USA Rizky Abdulah, Universitas Padjadjaran, Indonesia Aty Widyawaruyanti, Universitas Airlangga, Indonesia Maywan Hariono, Universiti Sains Malaysia, Malaysia Auliya A. Suwantika, Universitas Padjadjaran, Indonesia Irma Melyani Puspitasari, Universitas Padjadjaran, Indonesia Rano K. Sinuraya, Universitas Padjadjaran, Indonesia Aris Widayati, Universitas Muhammadiyah Yogyakarta, Indonesia Sri Hartati Yuliani, Universitas Sanata Dharma, Indonesia Yustina Sri Hartini, Universitas Sanata Dharma, Indonesia Christine Patramurti, Universitas Sanata Dharma, Indonesia Managing Editor Michael Raharja Gani, Universitas Sanata Dharma, Indonesia Dina Christin Ayuning Putri, Universitas Sanata Dharma, Indonesia Zita Dhirani Pramono, Universitas Sanata Dharma, Indonesia Proofreading Center for Journal Publishing, Universitas Sanata Dharma SEKRETARIAT JURNAL FARMASI SAINS DAN KOMUNITAS Faculty of Pharmacy Universitas Sanata Dharma, Campus III Paingan, Maguwoharjo, Depok, Yogyakarta 55282; Phone: +62 (274) 883037, 883968 ext.52328; Fax: +62 (274) 886529; Email: editorial.jpsc@usd.ac.id Website: http://e-journal.usd.ac.id/index.php/JFSK/ All orders for hardcopy of the journal may be sent via email to editorial.jpsc@usd.ac.id with the subject Order Journal. The price of an issue is IDR 100,000.00. The price is not included the packaging and postal delivery fees to the address of the subscribers. Payments should be performed via transfer to CIMB Niaga (Account holder: Lembaga Penelitian Univ. Sanata Dharma, Account Nr. 800077540800). The order will be executed when payment have been performed and the proof of payment has been scanned and sent accordingly. Jurnal Farmasi Sains dan Komunitas Vol. 19, No.2, November 2022 CONTENTS Research Articles High Frequency of CYP2A6*4, CYP2A6*7, and CYP2A6*9 Alleles Detected Among Patients with Type 2 Diabetic: Genetic Study in The Private Hospital in Yogyakarta Christine Patramurti, Dita Maria Virginia, Fenty Fenty, Christianus Heru Setiawan, Jeffry Julianus, Phebe Hendra, Nicholas Adi Perdana Susanto 53-61 Optimization of Nanosilver Synthesis Process with Bioreductor of Binahong Leaf Extract (Anredera cordifolia (Ten.) Steenis) Rini Dwiastuti, Elsa Irnandari, Michael Raharja Gani, Sri Hartati Yuliani, Christofori Maria Ratna Rini Nastiti 62-70 Profile of The Use of Traditional Medicines Among Adolescents in SMK Farmasi Teladan Demak Barnabas Bagus Aditya Abadi, Aris Widayati 71-77 Preparation of a Questionnaire for Clean and Healthy Behavior and Multivitamins to Measure Knowledge, Attitudes and Behavior as Prevention Efforts During the COVID-19 Pandemic Sisilia Christina Ari Widiastuti, Yosef Wijoyo, Nunung Priyatni 78-86 The Effect of Ethanol Extract of Marsilea crenata Presley Leaves on Rotenone-Induced Zebrafish Locomotor Activity Burhan Ma'arif, Faisal Akhmal Muslikh, Destiya Argo Pamuji Fihuda, Husnul Khotimah, Maximus M. Taek, Mangestuti Agil 87-92 Identification Bioactive Compound of Ethanol-Water Fraction of Coleus atropurpureus for Anti-rheumatic Rheumatism in CFA-induced Rats Ipang Djunarko, Nanang Fakhrudin, Arief Nurrochmad, Subagus Wahyuono 93-102 Review Article The Epigenetic Impact of Vegetables-Derived Dietary Compounds in Neurodegenerative Conditions: A Review Vania Amanda Samor, Yurida Ni'ma Annisa, Muthi Ikawati, Nunung Yuniarti 103-112 Jurnal Farmasi Sains dan Komunitas Vol. 19, No.2, November 2022 Cover picture: See Patramurti et al., pp. 53-61 Figure 1. ElectrophoregramePCR product identification of CYP2A6*4 (A), CYP2A6*7 (B), and CYP2A6*9 (C) allele gene among the respondets. M1: Marker DNA Ladder. 1-7: Amplicon obtained among the respondents Figure 2. The HbA1c Distribution among Respondent according to their CPD. o: Outliyer value of HbA1c Levels x: Avarage of HbA1c Levels